locus-tag class description DIR45_00005 PF08299 Bacterial dnaA protein helix-turn-helix DIR45_00005 PF00308 Bacterial dnaA protein DIR45_00005 PF11638 DnaA N-terminal domain DIR45_00010 PF00712 DNA polymerase III beta subunit, N-terminal domain DIR45_00010 PF02767 DNA polymerase III beta subunit, central domain DIR45_00010 PF02768 DNA polymerase III beta subunit, C-terminal domain DIR45_00020 PF02463 RecF/RecN/SMC N terminal domain DIR45_00025 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_00025 PF00204 DNA gyrase B DIR45_00025 PF01751 Toprim domain DIR45_00025 PF00986 DNA gyrase B subunit, carboxyl terminus DIR45_00030 PF03989 DNA gyrase C-terminal domain, beta-propeller DIR45_00030 PF00521 DNA gyrase/topoisomerase IV, subunit A DIR45_00060 PF14175 YaaC-like Protein DIR45_00065 PF00478 IMP dehydrogenase / GMP reductase domain DIR45_00065 PF00571 CBS domain DIR45_00070 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_00070 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_00075 PF01680 SOR/SNZ family DIR45_00080 PF01174 SNO glutamine amidotransferase family DIR45_00085 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_00085 PF02403 Seryl-tRNA synthetase N-terminal domain DIR45_00100 PF01712 Deoxynucleoside kinase DIR45_00105 PF01712 Deoxynucleoside kinase DIR45_00110 PF00857 Isochorismatase family DIR45_00120 PF14437 MafB19-like deaminase DIR45_00130 PF12169 DNA polymerase III subunits gamma and tau domain III DIR45_00135 PF02575 YbaB/EbfC DNA-binding family DIR45_00140 PF02132 RecR protein DIR45_00140 PF13662 Toprim domain DIR45_00145 PF10704 Protein of unknown function (DUF2508) DIR45_00150 PF07441 SigmaK-factor processing regulatory protein BofA DIR45_00185 PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain DIR45_00185 PF01276 Orn/Lys/Arg decarboxylase, major domain DIR45_00190 PF02223 Thymidylate kinase DIR45_00195 PF09115 DNA polymerase III, delta subunit, C terminal DIR45_00200 PF04468 PSP1 C-terminal conserved region DIR45_00205 PF06156 Initiation control protein YabA DIR45_00210 PF05175 Methyltransferase small domain DIR45_00215 PF01541 GIY-YIG catalytic domain DIR45_00220 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases DIR45_00225 PF18277 AbrB C-terminal domain DIR45_00225 PF04014 Antidote-toxin recognition MazE, bacterial antitoxin DIR45_00230 PF09334 tRNA synthetases class I (M) DIR45_00230 PF01588 Putative tRNA binding domain DIR45_00230 PF08264 Anticodon-binding domain of tRNA DIR45_00235 PF01026 TatD related DNase DIR45_00240 PF13331 Domain of unknown function (DUF4093) DIR45_00240 PF13662 Toprim domain DIR45_00245 PF00398 Ribosomal RNA adenine dimethylase DIR45_00250 PF05582 YabG peptidase U57 DIR45_00255 PF06257 Biofilm formation stimulator VEG DIR45_00260 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_00265 PF00288 GHMP kinases N terminal domain DIR45_00265 PF08544 GHMP kinases C terminal DIR45_00270 PF00156 Phosphoribosyl transferase domain DIR45_00270 PF09182 Bacterial purine repressor, N-terminal DIR45_00280 PF01042 Endoribonuclease L-PSP DIR45_00285 PF04026 SpoVG DIR45_00290 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_00290 PF00483 Nucleotidyl transferase DIR45_00295 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase DIR45_00295 PF14572 Phosphoribosyl synthetase-associated domain DIR45_00300 PF01195 Peptidyl-tRNA hydrolase DIR45_00310 PF02559 CarD-like/TRCF domain DIR45_00310 PF00271 Helicase conserved C-terminal domain DIR45_00310 PF03461 TRCF domain DIR45_00310 PF17757 UvrB interaction domain DIR45_00310 PF00270 DEAD/DEAH box helicase DIR45_00315 PF04014 Antidote-toxin recognition MazE, bacterial antitoxin DIR45_00315 PF15714 Stage V sporulation protein T C-terminal, transcription factor DIR45_00320 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_00320 PF01943 Polysaccharide biosynthesis protein DIR45_00325 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases DIR45_00325 PF03819 MazG nucleotide pyrophosphohydrolase domain DIR45_00330 PF01479 S4 domain DIR45_00335 PF07873 YabP family DIR45_00340 PF09578 Spore cortex protein YabQ (Spore_YabQ) DIR45_00350 PF00575 S1 RNA binding domain DIR45_00365 PF07228 Stage II sporulation protein E (SpoIIE) DIR45_00370 PF11734 TilS substrate C-terminal domain DIR45_00370 PF09179 TilS substrate binding domain DIR45_00370 PF01171 PP-loop family DIR45_00380 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_00380 PF17862 AAA+ lid domain DIR45_00380 PF01434 Peptidase family M41 DIR45_00380 PF06480 FtsH Extracellular DIR45_00385 PF03309 Type III pantothenate kinase DIR45_00390 PF01430 Hsp33 protein DIR45_00395 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_00400 PF00425 chorismate binding enzyme DIR45_00400 PF04715 Anthranilate synthase component I, N terminal region DIR45_00405 PF00117 Glutamine amidotransferase class-I DIR45_00410 PF01063 Amino-transferase class IV DIR45_00415 PF00809 Pterin binding enzyme DIR45_00420 PF02152 Dihydroneopterin aldolase DIR45_00425 PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DIR45_00430 PF01381 Helix-turn-helix DIR45_00435 PF01207 Dihydrouridine synthase (Dus) DIR45_00440 PF01336 OB-fold nucleic acid binding domain DIR45_00440 PF00152 tRNA synthetases class II (D, K and N) DIR45_00460 PF05848 CtsR N-terminal HTH domain DIR45_00460 PF17727 CtsR C-terminal dimerization domain DIR45_00465 PF02151 UvrB/uvrC motif DIR45_00470 PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain DIR45_00475 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_00475 PF07724 AAA domain (Cdc48 subfamily) DIR45_00475 PF17871 AAA lid domain DIR45_00475 PF02861 Clp amino terminal domain, pathogenicity island component DIR45_00475 PF10431 C-terminal, D2-small domain, of ClpB protein DIR45_00480 PF18073 Rubredoxin metal binding domain DIR45_00485 PF02457 DisA bacterial checkpoint controller nucleotide-binding DIR45_00485 PF10635 DisA bacterial checkpoint controller linker region DIR45_00495 PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DIR45_00500 PF02542 YgbB family DIR45_00505 PF00749 tRNA synthetases class I (E and Q), catalytic domain DIR45_00510 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_00510 PF06426 Serine acetyltransferase, N-terminal DIR45_00515 PF01406 tRNA synthetases class I (C) catalytic domain DIR45_00515 PF09190 DALR domain DIR45_00520 PF00636 Ribonuclease III domain DIR45_00525 PF00588 SpoU rRNA Methylase family DIR45_00525 PF08032 RNA 2'-O ribose methyltransferase substrate binding DIR45_00530 PF05991 YacP-like NYN domain DIR45_00535 PF04542 Sigma-70 region 2 DIR45_00535 PF08281 Sigma-70, region 4 DIR45_00540 PF00471 Ribosomal protein L33 DIR45_00545 PF00584 SecE/Sec61-gamma subunits of protein translocation complex DIR45_00550 PF00467 KOW motif DIR45_00550 PF02357 Transcription termination factor nusG DIR45_00555 PF00298 Ribosomal protein L11, RNA binding domain DIR45_00555 PF03946 Ribosomal protein L11, N-terminal domain DIR45_00560 PF00687 Ribosomal protein L1p/L10e family DIR45_00565 PF00466 Ribosomal protein L10 DIR45_00570 PF00542 Ribosomal protein L7/L12 C-terminal domain DIR45_00570 PF16320 Ribosomal protein L7/L12 dimerisation domain DIR45_00575 PF05175 Methyltransferase small domain DIR45_00580 PF00562 RNA polymerase Rpb2, domain 6 DIR45_00580 PF04565 RNA polymerase Rpb2, domain 3 DIR45_00580 PF04561 RNA polymerase Rpb2, domain 2 DIR45_00580 PF04563 RNA polymerase beta subunit DIR45_00580 PF10385 RNA polymerase beta subunit external 1 domain DIR45_00580 PF04560 RNA polymerase Rpb2, domain 7 DIR45_00585 PF04998 RNA polymerase Rpb1, domain 5 DIR45_00585 PF05000 RNA polymerase Rpb1, domain 4 DIR45_00585 PF04997 RNA polymerase Rpb1, domain 1 DIR45_00585 PF00623 RNA polymerase Rpb1, domain 2 DIR45_00585 PF04983 RNA polymerase Rpb1, domain 3 DIR45_00590 PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DIR45_00595 PF00164 Ribosomal protein S12/S23 DIR45_00600 PF00177 Ribosomal protein S7p/S5e DIR45_00605 PF03764 Elongation factor G, domain IV DIR45_00605 PF00679 Elongation factor G C-terminus DIR45_00605 PF03144 Elongation factor Tu domain 2 DIR45_00605 PF00009 Elongation factor Tu GTP binding domain DIR45_00605 PF14492 Elongation Factor G, domain II DIR45_00610 PF03143 Elongation factor Tu C-terminal domain DIR45_00610 PF00009 Elongation factor Tu GTP binding domain DIR45_00610 PF03144 Elongation factor Tu domain 2 DIR45_00615 PF00338 Ribosomal protein S10p/S20e DIR45_00620 PF00297 Ribosomal protein L3 DIR45_00625 PF00573 Ribosomal protein L4/L1 family DIR45_00630 PF00276 Ribosomal protein L23 DIR45_00635 PF00181 Ribosomal Proteins L2, RNA binding domain DIR45_00635 PF03947 Ribosomal Proteins L2, C-terminal domain DIR45_00640 PF00203 Ribosomal protein S19 DIR45_00645 PF00237 Ribosomal protein L22p/L17e DIR45_00650 PF00189 Ribosomal protein S3, C-terminal domain DIR45_00650 PF07650 KH domain DIR45_00655 PF00252 Ribosomal protein L16p/L10e DIR45_00660 PF00831 Ribosomal L29 protein DIR45_00665 PF00366 Ribosomal protein S17 DIR45_00670 PF00238 Ribosomal protein L14p/L23e DIR45_00675 PF00467 KOW motif DIR45_00675 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 DIR45_00680 PF00673 ribosomal L5P family C-terminus DIR45_00680 PF00281 Ribosomal protein L5 DIR45_00685 PF00253 Ribosomal protein S14p/S29e DIR45_00690 PF00410 Ribosomal protein S8 DIR45_00695 PF00347 Ribosomal protein L6 DIR45_00700 PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DIR45_00705 PF03719 Ribosomal protein S5, C-terminal domain DIR45_00705 PF00333 Ribosomal protein S5, N-terminal domain DIR45_00710 PF00327 Ribosomal protein L30p/L7e DIR45_00715 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DIR45_00720 PF00344 SecY translocase DIR45_00725 PF05191 Adenylate kinase, active site lid DIR45_00730 PF00557 Metallopeptidase family M24 DIR45_00735 PF01176 Translation initiation factor 1A / IF-1 DIR45_00740 PF00444 Ribosomal protein L36 DIR45_00745 PF00416 Ribosomal protein S13/S18 DIR45_00750 PF00411 Ribosomal protein S11 DIR45_00755 PF01000 RNA polymerase Rpb3/RpoA insert domain DIR45_00755 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain DIR45_00755 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain DIR45_00760 PF01196 Ribosomal protein L17 DIR45_00765 PF00005 ABC transporter DIR45_00770 PF00005 ABC transporter DIR45_00775 PF02361 Cobalt transport protein DIR45_00780 PF01416 tRNA pseudouridine synthase DIR45_00785 PF00572 Ribosomal protein L13 DIR45_00790 PF00380 Ribosomal protein S9/S16 DIR45_00800 PF01520 N-acetylmuramoyl-L-alanine amidase DIR45_00805 PF10609 NUBPL iron-transfer P-loop NTPase DIR45_00810 PF17898 Spore germination GerD central core domain DIR45_00815 PF14089 KinB-signalling pathway activation in sporulation DIR45_00820 PF01522 Polysaccharide deacetylase DIR45_00900 PF00491 Arginase family DIR45_00905 PF02457 DisA bacterial checkpoint controller nucleotide-binding DIR45_00910 PF07949 YbbR-like protein DIR45_00915 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DIR45_00915 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain DIR45_00915 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DIR45_00915 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DIR45_00925 PF01380 SIS domain DIR45_00930 PF00561 alpha/beta hydrolase fold DIR45_00935 PF07729 FCD domain DIR45_00935 PF00392 Bacterial regulatory proteins, gntR family DIR45_00940 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_00940 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_00945 PF02447 GntP family permease DIR45_00950 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase DIR45_00950 PF00393 6-phosphogluconate dehydrogenase, C-terminal domain DIR45_00960 PF07676 WD40-like Beta Propeller Repeat DIR45_00960 PF00326 Prolyl oligopeptidase family DIR45_00995 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01000 PF00005 ABC transporter DIR45_01000 PF09383 NIL domain DIR45_01005 PF03180 NLPA lipoprotein DIR45_01025 PF07690 Major Facilitator Superfamily DIR45_01035 PF07690 Major Facilitator Superfamily DIR45_01050 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01055 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01055 PF12911 N-terminal TM domain of oligopeptide transport permease C DIR45_01060 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_01060 PF00005 ABC transporter DIR45_01065 PF00005 ABC transporter DIR45_01065 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_01070 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_01080 PF12833 Helix-turn-helix domain DIR45_01095 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_01100 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_01105 PF00248 Aldo/keto reductase family DIR45_01110 PF14748 Pyrroline-5-carboxylate reductase dimerisation DIR45_01110 PF03807 NADP oxidoreductase coenzyme F420-dependent DIR45_01120 PF04973 Nicotinamide mononucleotide transporter DIR45_01125 PF06800 Sugar transport protein DIR45_01130 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01140 PF12727 PBP superfamily domain DIR45_01140 PF12728 Helix-turn-helix domain DIR45_01155 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_01155 PF03466 LysR substrate binding domain DIR45_01160 PF00892 EamA-like transporter family DIR45_01165 PF14142 YrzO-like protein DIR45_01175 PF01553 Acyltransferase DIR45_01190 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family DIR45_01190 PF00356 Bacterial regulatory proteins, lacI family DIR45_01200 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_01200 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_01215 PF01026 TatD related DNase DIR45_01220 PF10096 Uncharacterized protein conserved in bacteria (DUF2334) DIR45_01245 PF16326 ABC transporter C-terminal domain DIR45_01245 PF12848 ABC transporter DIR45_01245 PF00005 ABC transporter DIR45_01260 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_01265 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01275 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_01275 PF00005 ABC transporter DIR45_01280 PF00005 ABC transporter DIR45_01280 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_01315 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_01320 PF01557 Fumarylacetoacetate (FAA) hydrolase family DIR45_01335 PF07690 Major Facilitator Superfamily DIR45_01345 PF01225 Mur ligase family, catalytic domain DIR45_01345 PF08245 Mur ligase middle domain DIR45_01345 PF02875 Mur ligase family, glutamate ligase domain DIR45_01350 PF00271 Helicase conserved C-terminal domain DIR45_01350 PF00270 DEAD/DEAH box helicase DIR45_01355 PF03851 UV-endonuclease UvdE DIR45_01360 PF01694 Rhomboid family DIR45_01365 PF01648 4'-phosphopantetheinyl transferase superfamily DIR45_01375 PF01168 Alanine racemase, N-terminal domain DIR45_01375 PF00842 Alanine racemase, C-terminal domain DIR45_01380 PF01402 Ribbon-helix-helix protein, copG family DIR45_01385 PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system DIR45_01390 PF16921 Tex protein YqgF-like domain DIR45_01390 PF09371 Tex-like protein N-terminal domain DIR45_01390 PF00575 S1 RNA binding domain DIR45_01390 PF17674 HHH domain DIR45_01400 PF17283 SprT-like zinc ribbon domain DIR45_01400 PF10263 SprT-like family DIR45_01485 PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE DIR45_01490 PF00814 Glycoprotease family DIR45_01495 PF00583 Acetyltransferase (GNAT) family DIR45_01500 PF00814 Glycoprotease family DIR45_01505 PF12848 ABC transporter DIR45_01505 PF16326 ABC transporter C-terminal domain DIR45_01505 PF00005 ABC transporter DIR45_01510 PF06971 Putative DNA-binding protein N-terminus DIR45_01510 PF02629 CoA binding domain DIR45_01520 PF02517 CPBP intramembrane metalloprotease DIR45_01525 PF00166 Chaperonin 10 Kd subunit DIR45_01530 PF00118 TCP-1/cpn60 chaperonin family DIR45_01535 PF02540 NAD synthase DIR45_01535 PF00117 Glutamine amidotransferase class-I DIR45_01535 PF00958 GMP synthase C terminal domain DIR45_01540 PF00860 Permease family DIR45_01545 PF00486 Transcriptional regulatory protein, C terminal DIR45_01545 PF00072 Response regulator receiver domain DIR45_01550 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_01550 PF00512 His Kinase A (phospho-acceptor) domain DIR45_01550 PF00989 PAS fold DIR45_01550 PF16736 Single Cache-like DIR45_01575 PF02673 Bacitracin resistance protein BacA DIR45_01585 PF00005 ABC transporter DIR45_01590 PF00512 His Kinase A (phospho-acceptor) domain DIR45_01590 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_01595 PF00486 Transcriptional regulatory protein, C terminal DIR45_01595 PF00072 Response regulator receiver domain DIR45_01620 PF00731 AIR carboxylase DIR45_01625 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain DIR45_01625 PF02222 ATP-grasp domain DIR45_01630 PF00206 Lyase DIR45_01630 PF10397 Adenylosuccinate lyase C-terminus DIR45_01635 PF01259 SAICAR synthetase DIR45_01640 PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase DIR45_01650 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain DIR45_01650 PF02769 AIR synthase related protein, C-terminal domain DIR45_01650 PF00586 AIR synthase related protein, N-terminal domain DIR45_01655 PF00156 Phosphoribosyl transferase domain DIR45_01660 PF02769 AIR synthase related protein, C-terminal domain DIR45_01660 PF00586 AIR synthase related protein, N-terminal domain DIR45_01665 PF00551 Formyl transferase DIR45_01670 PF01808 AICARFT/IMPCHase bienzyme DIR45_01670 PF02142 MGS-like domain DIR45_01675 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DIR45_01675 PF02844 Phosphoribosylglycinamide synthetase, N domain DIR45_01675 PF02843 Phosphoribosylglycinamide synthetase, C domain DIR45_01700 PF01884 PcrB family DIR45_01705 PF13361 UvrD-like helicase C-terminal domain DIR45_01705 PF00580 UvrD/REP helicase N-terminal domain DIR45_01710 PF03119 NAD-dependent DNA ligase C4 zinc finger domain DIR45_01710 PF12826 Helix-hairpin-helix motif DIR45_01710 PF03120 NAD-dependent DNA ligase OB-fold domain DIR45_01710 PF01653 NAD-dependent DNA ligase adenylation domain DIR45_01710 PF00533 BRCA1 C Terminus (BRCT) domain DIR45_01715 PF07537 CamS sex pheromone cAM373 precursor DIR45_01720 PF01925 Sulfite exporter TauE/SafE DIR45_01725 PF00171 Aldehyde dehydrogenase family DIR45_01735 PF00857 Isochorismatase family DIR45_01745 PF09383 NIL domain DIR45_01745 PF00005 ABC transporter DIR45_01750 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_01755 PF03180 NLPA lipoprotein DIR45_01775 PF01047 MarR family DIR45_01785 PF02686 Glu-tRNAGln amidotransferase C subunit DIR45_01790 PF01425 Amidase DIR45_01795 PF02934 GatB/GatE catalytic domain DIR45_01795 PF02637 GatB domain DIR45_01800 PF00781 Diacylglycerol kinase catalytic domain DIR45_01805 PF13419 Haloacid dehalogenase-like hydrolase DIR45_01810 PF00202 Aminotransferase class-III DIR45_01815 PF00158 Sigma-54 interaction domain DIR45_01820 PF00171 Aldehyde dehydrogenase family DIR45_01825 PF00893 Small Multidrug Resistance protein DIR45_01830 PF02073 Thermophilic metalloprotease (M29) DIR45_01845 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_01845 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_01845 PF07670 Nucleoside recognition DIR45_01850 PF02475 Met-10+ like-protein DIR45_01850 PF01938 TRAM domain DIR45_01850 PF05958 tRNA (Uracil-5-)-methyltransferase DIR45_01855 PF01207 Dihydrouridine synthase (Dus) DIR45_01865 PF07308 Protein of unknown function (DUF1456) DIR45_01880 PF13378 Enolase C-terminal domain-like DIR45_01880 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DIR45_01895 PF01546 Peptidase family M20/M25/M40 DIR45_01895 PF07687 Peptidase dimerisation domain DIR45_01905 PF13192 Thioredoxin domain DIR45_01905 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_01910 PF00578 AhpC/TSA family DIR45_01915 PF01636 Phosphotransferase enzyme family DIR45_01925 PF00596 Class II Aldolase and Adducin N-terminal domain DIR45_01930 PF01032 FecCD transport family DIR45_01935 PF01032 FecCD transport family DIR45_01940 PF01497 Periplasmic binding protein DIR45_01950 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_01965 PF12728 Helix-turn-helix domain DIR45_02010 PF13188 PAS domain DIR45_02010 PF00512 His Kinase A (phospho-acceptor) domain DIR45_02010 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_02010 PF13426 PAS domain DIR45_02010 PF00989 PAS fold DIR45_02030 PF10127 RNA repair pathway DNA polymerase beta family DIR45_02035 PF07690 Major Facilitator Superfamily DIR45_02040 PF01266 FAD dependent oxidoreductase DIR45_02040 PF00355 Rieske [2Fe-2S] domain DIR45_02050 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_02055 PF00497 Bacterial extracellular solute-binding proteins, family 3 DIR45_02060 PF00005 ABC transporter DIR45_02070 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_02070 PF00672 HAMP domain DIR45_02070 PF12729 Four helix bundle sensory module for signal transduction DIR45_02075 PF12729 Four helix bundle sensory module for signal transduction DIR45_02075 PF00672 HAMP domain DIR45_02075 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_02080 PF16657 Maltogenic Amylase, C-terminal domain DIR45_02080 PF00128 Alpha amylase, catalytic domain DIR45_02085 PF00367 phosphotransferase system, EIIB DIR45_02085 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DIR45_02085 PF02378 Phosphotransferase system, EIIC DIR45_02090 PF03372 Endonuclease/Exonuclease/phosphatase family DIR45_02095 PF01061 ABC-2 type transporter DIR45_02100 PF01131 DNA topoisomerase DIR45_02100 PF01751 Toprim domain DIR45_02105 PF02110 Hydroxyethylthiazole kinase family DIR45_02110 PF02581 Thiamine monophosphate synthase DIR45_02115 PF03605 Anaerobic c4-dicarboxylate membrane transporter DIR45_02120 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_02120 PF00672 HAMP domain DIR45_02125 PF01910 Thiamine-binding protein DIR45_02130 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_02140 PF00005 ABC transporter DIR45_02145 PF00005 ABC transporter DIR45_02145 PF12848 ABC transporter DIR45_02170 PF00440 Bacterial regulatory proteins, tetR family DIR45_02170 PF08360 QacR-like protein, C-terminal region DIR45_02190 PF11700 Vacuole effluxer Atg22 like DIR45_02205 PF03129 Anticodon binding domain DIR45_02205 PF09180 Prolyl-tRNA synthetase, C-terminal DIR45_02205 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_02215 PF00480 ROK family DIR45_02220 PF02342 TerD domain DIR45_02225 PF02342 TerD domain DIR45_02230 PF02342 TerD domain DIR45_02235 PF03741 Integral membrane protein TerC family DIR45_02240 PF14266 Putative component of 'biosynthetic module' DIR45_02245 PF05816 Toxic anion resistance protein (TelA) DIR45_02250 PF00690 Cation transporter/ATPase, N-terminus DIR45_02250 PF00689 Cation transporting ATPase, C-terminus DIR45_02255 PF06569 Protein of unknown function (DUF1128) DIR45_02260 PF01451 Low molecular weight phosphotyrosine protein phosphatase DIR45_02270 PF03631 Virulence factor BrkB DIR45_02285 PF00892 EamA-like transporter family DIR45_02295 PF10502 Signal peptidase, peptidase S26 DIR45_02305 PF09335 SNARE associated Golgi protein DIR45_02320 PF16242 Pyridoxamine 5'-phosphate oxidase like DIR45_02325 PF01699 Sodium/calcium exchanger protein DIR45_02330 PF14167 YfkD-like protein DIR45_02335 PF04055 Radical SAM superfamily DIR45_02335 PF08756 YfkB-like domain DIR45_02345 PF05681 Fumarate hydratase (Fumerase) DIR45_02345 PF05683 Fumarase C-terminus DIR45_02350 PF01522 Polysaccharide deacetylase DIR45_02360 PF00730 HhH-GPD superfamily base excision DNA repair protein DIR45_02365 PF01938 TRAM domain DIR45_02365 PF05958 tRNA (Uracil-5-)-methyltransferase DIR45_02370 PF00589 Phage integrase family DIR45_02370 PF14659 Phage integrase, N-terminal SAM-like domain DIR45_02375 PF01381 Helix-turn-helix DIR45_02395 PF01381 Helix-turn-helix DIR45_02430 PF07319 Primosomal protein DnaI N-terminus DIR45_02430 PF01695 IstB-like ATP binding protein DIR45_02535 PF00589 Phage integrase family DIR45_02540 PF00589 Phage integrase family DIR45_02675 PF01183 Glycosyl hydrolases family 25 DIR45_02685 PF01416 tRNA pseudouridine synthase DIR45_02695 PF02954 Bacterial regulatory protein, Fis family DIR45_02695 PF13426 PAS domain DIR45_02695 PF00158 Sigma-54 interaction domain DIR45_02705 PF00324 Amino acid permease DIR45_02710 PF01546 Peptidase family M20/M25/M40 DIR45_02710 PF07687 Peptidase dimerisation domain DIR45_02740 PF04960 Glutaminase DIR45_02750 PF02378 Phosphotransferase system, EIIC DIR45_02750 PF00367 phosphotransferase system, EIIB DIR45_02755 PF00144 Beta-lactamase DIR45_02770 PF00535 Glycosyl transferase family 2 DIR45_02775 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DIR45_02775 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIR45_02775 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain DIR45_02780 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIR45_02780 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain DIR45_02780 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DIR45_02785 PF00551 Formyl transferase DIR45_02785 PF02911 Formyl transferase, C-terminal domain DIR45_02785 PF01370 NAD dependent epimerase/dehydratase family DIR45_02790 PF00535 Glycosyl transferase family 2 DIR45_02800 PF01228 Glycine radical DIR45_02800 PF02901 Pyruvate formate lyase-like DIR45_02805 PF04055 Radical SAM superfamily DIR45_02810 PF04101 Glycosyltransferase family 28 C-terminal domain DIR45_02810 PF06925 Monogalactosyldiacylglycerol (MGDG) synthase DIR45_02825 PF01979 Amidohydrolase family DIR45_02830 PF01370 NAD dependent epimerase/dehydratase family DIR45_02830 PF08338 Domain of unknown function (DUF1731) DIR45_02835 PF02631 RecX family DIR45_02850 PF08176 Small acid-soluble spore protein K family DIR45_02855 PF14043 WVELL protein DIR45_02860 PF04307 LexA-binding, inner membrane-associated putative hydrolase DIR45_02865 PF14815 NUDIX domain DIR45_02865 PF00730 HhH-GPD superfamily base excision DNA repair protein DIR45_02875 PF04259 Small, acid-soluble spore protein, gamma-type DIR45_02880 PF14182 YgaB-like protein DIR45_02885 PF04167 Protein of unknown function (DUF402) DIR45_02890 PF00005 ABC transporter DIR45_02890 PF00664 ABC transporter transmembrane region DIR45_02895 PF06081 Aromatic acid exporter family member 1 DIR45_02900 PF01645 Conserved region in glutamate synthase DIR45_02900 PF04898 Glutamate synthase central domain DIR45_02900 PF00310 Glutamine amidotransferases class-II DIR45_02900 PF01493 GXGXG motif DIR45_02905 PF00202 Aminotransferase class-III DIR45_02910 PF00005 ABC transporter DIR45_02925 PF07885 Ion channel DIR45_02930 PF00578 AhpC/TSA family DIR45_02935 PF01475 Ferric uptake regulator family DIR45_02940 PF11023 Zinc-ribbon containing domain DIR45_03045 PF01709 Transcriptional regulator DIR45_03050 PF00293 NUDIX domain DIR45_03050 PF13344 Haloacid dehalogenase-like hydrolase DIR45_03055 PF00912 Transglycosylase DIR45_03055 PF00905 Penicillin binding protein transpeptidase domain DIR45_03060 PF13462 Thioredoxin DIR45_03070 PF08331 Domain of unknown function (DUF1730) DIR45_03075 PF12671 Putative amidase domain DIR45_03080 PF00588 SpoU rRNA Methylase family DIR45_03085 PF03707 Bacterial signalling protein N terminal repeat DIR45_03085 PF00563 EAL domain DIR45_03085 PF00990 Diguanylate cyclase, GGDEF domain DIR45_03095 PF08298 PrkA AAA domain DIR45_03095 PF06798 PrkA serine protein kinase C-terminal domain DIR45_03110 PF04285 Protein of unknown function (DUF444) DIR45_03125 PF02028 BCCT, betaine/carnitine/choline family transporter DIR45_03130 PF18496 Collagenase G catalytic helper subdomain DIR45_03130 PF08453 Peptidase family M9 N-terminal DIR45_03130 PF01752 Collagenase DIR45_03140 PF01145 SPFH domain / Band 7 family DIR45_03140 PF15975 Flotillin DIR45_03145 PF00672 HAMP domain DIR45_03145 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_03145 PF02743 Cache domain DIR45_03150 PF00989 PAS fold DIR45_03150 PF17203 Single cache domain 3 DIR45_03150 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain DIR45_03150 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_03155 PF00072 Response regulator receiver domain DIR45_03155 PF08279 HTH domain DIR45_03155 PF12431 Transcriptional regulator DIR45_03160 PF03600 Citrate transporter DIR45_03185 PF04309 Glycerol-3-phosphate responsive antiterminator DIR45_03190 PF17912 MalK OB fold domain DIR45_03190 PF00005 ABC transporter DIR45_03195 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03200 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03205 PF13416 Bacterial extracellular solute-binding protein DIR45_03210 PF00149 Calcineurin-like phosphoesterase DIR45_03215 PF00072 Response regulator receiver domain DIR45_03215 PF00486 Transcriptional regulatory protein, C terminal DIR45_03220 PF00512 His Kinase A (phospho-acceptor) domain DIR45_03220 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_03230 PF13529 Peptidase_C39 like family DIR45_03235 PF00672 HAMP domain DIR45_03235 PF02743 Cache domain DIR45_03235 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_03240 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain DIR45_03240 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_03240 PF00989 PAS fold DIR45_03240 PF17203 Single cache domain 3 DIR45_03245 PF00072 Response regulator receiver domain DIR45_03250 PF03390 2-hydroxycarboxylate transporter family DIR45_03255 PF00390 Malic enzyme, N-terminal domain DIR45_03255 PF03949 Malic enzyme, NAD binding domain DIR45_03265 PF00892 EamA-like transporter family DIR45_03270 PF00155 Aminotransferase class I and II DIR45_03270 PF00392 Bacterial regulatory proteins, gntR family DIR45_03280 PF00989 PAS fold DIR45_03280 PF18698 Histidine kinase sensor domain DIR45_03280 PF00672 HAMP domain DIR45_03280 PF00512 His Kinase A (phospho-acceptor) domain DIR45_03280 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_03285 PF00486 Transcriptional regulatory protein, C terminal DIR45_03285 PF00072 Response regulator receiver domain DIR45_03295 PF13508 Acetyltransferase (GNAT) domain DIR45_03295 PF00583 Acetyltransferase (GNAT) family DIR45_03300 PF02634 FdhD/NarQ family DIR45_03305 PF00037 4Fe-4S binding domain DIR45_03305 PF04879 Molybdopterin oxidoreductase Fe4S4 domain DIR45_03305 PF00384 Molybdopterin oxidoreductase DIR45_03305 PF01568 Molydopterin dinucleotide binding domain DIR45_03305 PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DIR45_03310 PF07849 Protein of unknown function (DUF1641) DIR45_03320 PF01262 Alanine dehydrogenase/PNT, C-terminal domain DIR45_03320 PF05222 Alanine dehydrogenase/PNT, N-terminal domain DIR45_03325 PF13520 Amino acid permease DIR45_03335 PF01022 Bacterial regulatory protein, arsR family DIR45_03340 PF00403 Heavy-metal-associated domain DIR45_03345 PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family DIR45_03345 PF17767 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DIR45_03345 PF17956 Nicotinate phosphoribosyltransferase C-terminal domain DIR45_03360 PF02868 Thermolysin metallopeptidase, alpha-helical domain DIR45_03360 PF01447 Thermolysin metallopeptidase, catalytic domain DIR45_03360 PF03413 Peptidase propeptide and YPEB domain DIR45_03360 PF07504 Fungalysin/Thermolysin Propeptide Motif DIR45_03380 PF04294 VanW like protein DIR45_03385 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_03390 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_03390 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_03395 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_03400 PF01595 Cyclin M transmembrane N-terminal domain DIR45_03400 PF03471 Transporter associated domain DIR45_03400 PF00571 CBS domain DIR45_03405 PF10415 Fumarase C C-terminus DIR45_03405 PF00206 Lyase DIR45_03410 PF02652 L-lactate permease DIR45_03415 PF01022 Bacterial regulatory protein, arsR family DIR45_03420 PF08141 Small acid-soluble spore protein H family DIR45_03425 PF00854 POT family DIR45_03430 PF01497 Periplasmic binding protein DIR45_03435 PF01032 FecCD transport family DIR45_03440 PF01032 FecCD transport family DIR45_03445 PF00005 ABC transporter DIR45_03450 PF08241 Methyltransferase domain DIR45_03455 PF00155 Aminotransferase class I and II DIR45_03460 PF01370 NAD dependent epimerase/dehydratase family DIR45_03465 PF00293 NUDIX domain DIR45_03465 PF13344 Haloacid dehalogenase-like hydrolase DIR45_03470 PF00092 von Willebrand factor type A domain DIR45_03475 PF07728 AAA domain (dynein-related subfamily) DIR45_03480 PF13396 Phospholipase_D-nuclease N-terminal DIR45_03480 PF13091 PLD-like domain DIR45_03495 PF00563 EAL domain DIR45_03495 PF00990 Diguanylate cyclase, GGDEF domain DIR45_03495 PF03707 Bacterial signalling protein N terminal repeat DIR45_03500 PF13520 Amino acid permease DIR45_03505 PF07702 UTRA domain DIR45_03505 PF00392 Bacterial regulatory proteins, gntR family DIR45_03510 PF00367 phosphotransferase system, EIIB DIR45_03510 PF02378 Phosphotransferase system, EIIC DIR45_03515 PF00128 Alpha amylase, catalytic domain DIR45_03515 PF16657 Maltogenic Amylase, C-terminal domain DIR45_03530 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_03540 PF01636 Phosphotransferase enzyme family DIR45_03545 PF01235 Sodium:alanine symporter family DIR45_03550 PF00005 ABC transporter DIR45_03555 PF00497 Bacterial extracellular solute-binding proteins, family 3 DIR45_03560 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03565 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03570 PF00324 Amino acid permease DIR45_03595 PF13280 WYL domain DIR45_03595 PF08279 HTH domain DIR45_03600 PF01872 RibD C-terminal domain DIR45_03605 PF00989 PAS fold DIR45_03605 PF00512 His Kinase A (phospho-acceptor) domain DIR45_03605 PF18698 Histidine kinase sensor domain DIR45_03605 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_03605 PF00672 HAMP domain DIR45_03610 PF00486 Transcriptional regulatory protein, C terminal DIR45_03610 PF00072 Response regulator receiver domain DIR45_03620 PF01740 STAS domain DIR45_03620 PF00916 Sulfate permease family DIR45_03625 PF00582 Universal stress protein family DIR45_03635 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_03640 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03645 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03650 PF00005 ABC transporter DIR45_03650 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_03655 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_03655 PF00005 ABC transporter DIR45_03660 PF07690 Major Facilitator Superfamily DIR45_03665 PF01047 MarR family DIR45_03675 PF00356 Bacterial regulatory proteins, lacI family DIR45_03680 PF00294 pfkB family carbohydrate kinase DIR45_03685 PF05025 RbsD / FucU transport protein family DIR45_03690 PF00005 ABC transporter DIR45_03695 PF02653 Branched-chain amino acid transport system / permease component DIR45_03700 PF13407 Periplasmic binding protein domain DIR45_03705 PF00923 Transaldolase/Fructose-6-phosphate aldolase DIR45_03710 PF05547 Immune inhibitor A peptidase M6 DIR45_03725 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_03725 PF00107 Zinc-binding dehydrogenase DIR45_03735 PF00882 Zinc dependent phospholipase C DIR45_03740 PF03372 Endonuclease/Exonuclease/phosphatase family DIR45_03765 PF02673 Bacitracin resistance protein BacA DIR45_03770 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_03770 PF00672 HAMP domain DIR45_03770 PF02743 Cache domain DIR45_03775 PF01476 LysM domain DIR45_03775 PF06725 3D domain DIR45_03780 PF01381 Helix-turn-helix DIR45_03790 PF04203 Sortase domain DIR45_03795 PF00854 POT family DIR45_03800 PF05525 Branched-chain amino acid transport protein DIR45_03815 PF00324 Amino acid permease DIR45_03820 PF00860 Permease family DIR45_03845 PF00999 Sodium/hydrogen exchanger family DIR45_03845 PF02080 TrkA-C domain DIR45_03845 PF02254 TrkA-N domain DIR45_03855 PF00510 Cytochrome c oxidase subunit III DIR45_03860 PF00115 Cytochrome C and Quinol oxidase polypeptide I DIR45_03865 PF02790 Cytochrome C oxidase subunit II, transmembrane domain DIR45_03870 PF00324 Amino acid permease DIR45_03875 PF13529 Peptidase_C39 like family DIR45_03880 PF07687 Peptidase dimerisation domain DIR45_03880 PF01546 Peptidase family M20/M25/M40 DIR45_03885 PF11755 Protein of unknown function (DUF3311) DIR45_03890 PF00474 Sodium:solute symporter family DIR45_03895 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_03900 PF03845 Spore germination protein DIR45_03915 PF07670 Nucleoside recognition DIR45_03915 PF02421 Ferrous iron transport protein B DIR45_03915 PF17910 FeoB cytosolic helical domain DIR45_03915 PF07664 Ferrous iron transport protein B C terminus DIR45_03920 PF07670 Nucleoside recognition DIR45_03920 PF17910 FeoB cytosolic helical domain DIR45_03920 PF07664 Ferrous iron transport protein B C terminus DIR45_03920 PF02421 Ferrous iron transport protein B DIR45_03925 PF07664 Ferrous iron transport protein B C terminus DIR45_03925 PF17910 FeoB cytosolic helical domain DIR45_03925 PF02421 Ferrous iron transport protein B DIR45_03925 PF04023 FeoA domain DIR45_03925 PF07670 Nucleoside recognition DIR45_03930 PF12849 PBP superfamily domain DIR45_03935 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03940 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_03950 PF00873 AcrB/AcrD/AcrF family DIR45_04070 PF00571 CBS domain DIR45_04090 PF00246 Zinc carboxypeptidase DIR45_04090 PF08239 Bacterial SH3 domain DIR45_04095 PF03070 TENA/THI-4/PQQC family DIR45_04100 PF00005 ABC transporter DIR45_04105 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_04110 PF09084 NMT1/THI5 like DIR45_04115 PF02581 Thiamine monophosphate synthase DIR45_04120 PF01266 FAD dependent oxidoreductase DIR45_04125 PF02597 ThiS family DIR45_04130 PF05690 Thiazole biosynthesis protein ThiG DIR45_04135 PF00899 ThiF family DIR45_04140 PF08543 Phosphomethylpyrimidine kinase DIR45_04170 PF03814 Potassium-transporting ATPase A subunit DIR45_04180 PF02669 K+-transporting ATPase, c chain DIR45_04185 PF02702 Osmosensitive K+ channel His kinase sensor domain DIR45_04190 PF07690 Major Facilitator Superfamily DIR45_04195 PF01047 MarR family DIR45_04210 PF00860 Permease family DIR45_04220 PF03734 L,D-transpeptidase catalytic domain DIR45_04220 PF17969 L,D-transpeptidase C-terminal domain DIR45_04230 PF00294 pfkB family carbohydrate kinase DIR45_04235 PF00251 Glycosyl hydrolases family 32 N-terminal domain DIR45_04235 PF08244 Glycosyl hydrolases family 32 C terminal DIR45_04240 PF02378 Phosphotransferase system, EIIC DIR45_04240 PF00367 phosphotransferase system, EIIB DIR45_04245 PF00356 Bacterial regulatory proteins, lacI family DIR45_04245 PF13407 Periplasmic binding protein domain DIR45_04255 PF00085 Thioredoxin DIR45_04260 PF02600 Disulfide bond formation protein DsbB DIR45_04265 PF14148 YhdB-like protein DIR45_04285 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_04295 PF00881 Nitroreductase family DIR45_04300 PF04293 SpoVR like protein DIR45_04330 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_04330 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_04335 PF02583 Metal-sensitive transcriptional repressor DIR45_04340 PF01206 Sulfurtransferase TusA DIR45_04340 PF00581 Rhodanese-like domain DIR45_04345 PF00753 Metallo-beta-lactamase superfamily DIR45_04345 PF00581 Rhodanese-like domain DIR45_04350 PF01206 Sulfurtransferase TusA DIR45_04355 PF00581 Rhodanese-like domain DIR45_04365 PF13686 DsrE/DsrF/DrsH-like family DIR45_04370 PF01925 Sulfite exporter TauE/SafE DIR45_04380 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_04385 PF00107 Zinc-binding dehydrogenase DIR45_04385 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_04390 PF02690 Na+/Pi-cotransporter DIR45_04395 PF07690 Major Facilitator Superfamily DIR45_04405 PF00874 PRD domain DIR45_04405 PF05043 Mga helix-turn-helix domain DIR45_04405 PF08279 HTH domain DIR45_04405 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DIR45_04410 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit DIR45_04415 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit DIR45_04420 PF02378 Phosphotransferase system, EIIC DIR45_04435 PF06725 3D domain DIR45_04435 PF01476 LysM domain DIR45_04440 PF02687 FtsX-like permease family DIR45_04440 PF12704 MacB-like periplasmic core domain DIR45_04445 PF00005 ABC transporter DIR45_04455 PF09529 Integral membrane protein (intg_mem_TP0381) DIR45_04470 PF05525 Branched-chain amino acid transport protein DIR45_04475 PF05067 Manganese containing catalase DIR45_04480 PF12652 CotJB protein DIR45_04485 PF11007 Spore coat associated protein JA (CotJA) DIR45_04500 PF02735 Ku70/Ku80 beta-barrel domain DIR45_04510 PF09335 SNARE associated Golgi protein DIR45_04545 PF13520 Amino acid permease DIR45_04550 PF00999 Sodium/hydrogen exchanger family DIR45_04560 PF01380 SIS domain DIR45_04560 PF01418 Helix-turn-helix domain, rpiR family DIR45_04565 PF01380 SIS domain DIR45_04570 PF00367 phosphotransferase system, EIIB DIR45_04570 PF02378 Phosphotransferase system, EIIC DIR45_04580 PF07681 DoxX DIR45_04595 PF00892 EamA-like transporter family DIR45_04600 PF01037 Lrp/AsnC ligand binding domain DIR45_04610 PF00893 Small Multidrug Resistance protein DIR45_04615 PF00893 Small Multidrug Resistance protein DIR45_04620 PF00440 Bacterial regulatory proteins, tetR family DIR45_04620 PF17934 Tetracyclin repressor-like, C-terminal domain DIR45_04625 PF07690 Major Facilitator Superfamily DIR45_04630 PF01638 HxlR-like helix-turn-helix DIR45_04640 PF02525 Flavodoxin-like fold DIR45_04645 PF12793 Sugar transport-related sRNA regulator N-term DIR45_04645 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_04650 PF07690 Major Facilitator Superfamily DIR45_04660 PF01965 DJ-1/PfpI family DIR45_04665 PF18011 C-terminal domain found in long catalases DIR45_04665 PF06628 Catalase-related immune-responsive DIR45_04665 PF00199 Catalase DIR45_04675 PF13520 Amino acid permease DIR45_04680 PF01177 Asp/Glu/Hydantoin racemase DIR45_04690 PF00171 Aldehyde dehydrogenase family DIR45_04710 PF00005 ABC transporter DIR45_04710 PF00664 ABC transporter transmembrane region DIR45_04725 PF00497 Bacterial extracellular solute-binding proteins, family 3 DIR45_04730 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_04735 PF00005 ABC transporter DIR45_04740 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_04750 PF14398 YheC/D like ATP-grasp DIR45_04760 PF04286 Protein of unknown function (DUF445) DIR45_04765 PF06133 Control of competence regulator ComK, YlbF/YmcA DIR45_04780 PF00205 Thiamine pyrophosphate enzyme, central domain DIR45_04780 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_04780 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_04785 PF03306 Alpha-acetolactate decarboxylase DIR45_04795 PF02245 Methylpurine-DNA glycosylase (MPG) DIR45_04810 PF01476 LysM domain DIR45_04810 PF01510 N-acetylmuramoyl-L-alanine amidase DIR45_04810 PF01471 Putative peptidoglycan binding domain DIR45_04820 PF04055 Radical SAM superfamily DIR45_04825 PF13193 AMP-binding enzyme C-terminal domain DIR45_04825 PF00501 AMP-binding enzyme DIR45_04835 PF01740 STAS domain DIR45_04835 PF00916 Sulfate permease family DIR45_04855 PF07517 SecA DEAD-like domain DIR45_04855 PF07516 SecA Wing and Scaffold domain DIR45_04855 PF01043 SecA preprotein cross-linking domain DIR45_04860 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_04860 PF01943 Polysaccharide biosynthesis protein DIR45_04870 PF02368 Bacterial Ig-like domain (group 2) DIR45_04870 PF13205 Bacterial Ig-like domain DIR45_04870 PF00395 S-layer homology domain DIR45_04875 PF00395 S-layer homology domain DIR45_04885 PF03062 MBOAT, membrane-bound O-acyltransferase family DIR45_04890 PF03062 MBOAT, membrane-bound O-acyltransferase family DIR45_04910 PF00378 Enoyl-CoA hydratase/isomerase DIR45_04930 PF05343 M42 glutamyl aminopeptidase DIR45_04935 PF00395 S-layer homology domain DIR45_04935 PF01520 N-acetylmuramoyl-L-alanine amidase DIR45_04945 PF11121 Protein of unknown function (DUF2639) DIR45_04950 PF05544 Proline racemase DIR45_04955 PF02423 Ornithine cyclodeaminase/mu-crystallin family DIR45_04960 PF18593 CdiI immunity protein DIR45_04980 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_04985 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_04990 PF12911 N-terminal TM domain of oligopeptide transport permease C DIR45_04990 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_05000 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_05000 PF00005 ABC transporter DIR45_05010 PF01541 GIY-YIG catalytic domain DIR45_05045 PF00083 Sugar (and other) transporter DIR45_05050 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_05050 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain DIR45_05055 PF08279 HTH domain DIR45_05055 PF00072 Response regulator receiver domain DIR45_05055 PF12431 Transcriptional regulator DIR45_05060 PF03401 Tripartite tricarboxylate transporter family receptor DIR45_05065 PF02342 TerD domain DIR45_05090 PF06445 GyrI-like small molecule binding domain DIR45_05090 PF13411 MerR HTH family regulatory protein DIR45_05105 PF00772 DnaB-like helicase N terminal domain DIR45_05105 PF03796 DnaB-like helicase C terminal domain DIR45_05135 PF01925 Sulfite exporter TauE/SafE DIR45_05155 PF07690 Major Facilitator Superfamily DIR45_05210 PF18665 Tetracyclin repressor-like, C-terminal domain DIR45_05210 PF00440 Bacterial regulatory proteins, tetR family DIR45_05230 PF01066 CDP-alcohol phosphatidyltransferase DIR45_05255 PF02733 Dak1 domain DIR45_05270 PF02733 Dak1 domain DIR45_05275 PF02525 Flavodoxin-like fold DIR45_05280 PF02082 Transcriptional regulator DIR45_05315 PF00672 HAMP domain DIR45_05315 PF01966 HD domain DIR45_05350 PF00395 S-layer homology domain DIR45_05375 PF11181 Heat induced stress protein YflT DIR45_05380 PF05532 CsbD-like DIR45_05395 PF01740 STAS domain DIR45_05400 PF13581 Histidine kinase-like ATPase domain DIR45_05405 PF04545 Sigma-70, region 4 DIR45_05405 PF04542 Sigma-70 region 2 DIR45_05405 PF04539 Sigma-70 region 3 DIR45_05415 PF07228 Stage II sporulation protein E (SpoIIE) DIR45_05415 PF13426 PAS domain DIR45_05420 PF01739 CheR methyltransferase, SAM binding domain DIR45_05420 PF03705 CheR methyltransferase, all-alpha domain DIR45_05425 PF00497 Bacterial extracellular solute-binding proteins, family 3 DIR45_05425 PF00072 Response regulator receiver domain DIR45_05425 PF01627 Hpt domain DIR45_05425 PF00512 His Kinase A (phospho-acceptor) domain DIR45_05425 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_05450 PF01906 Putative heavy-metal-binding DIR45_05465 PF00107 Zinc-binding dehydrogenase DIR45_05465 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_05470 PF11121 Protein of unknown function (DUF2639) DIR45_05485 PF00149 Calcineurin-like phosphoesterase DIR45_05490 PF13514 AAA domain DIR45_05495 PF07282 Putative transposase DNA-binding domain DIR45_05495 PF01385 Probable transposase DIR45_05495 PF12323 Helix-turn-helix domain DIR45_05505 PF01966 HD domain DIR45_05505 PF01336 OB-fold nucleic acid binding domain DIR45_05510 PF00440 Bacterial regulatory proteins, tetR family DIR45_05515 PF07690 Major Facilitator Superfamily DIR45_05520 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_05525 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_05530 PF18801 response regulator aspartate phosphatase H, N terminal DIR45_05540 PF00561 alpha/beta hydrolase fold DIR45_05540 PF08386 TAP-like protein DIR45_05560 PF04309 Glycerol-3-phosphate responsive antiterminator DIR45_05565 PF00230 Major intrinsic protein DIR45_05570 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_05570 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_05575 PF16901 C-terminal domain of alpha-glycerophosphate oxidase DIR45_05575 PF01266 FAD dependent oxidoreductase DIR45_05595 PF04542 Sigma-70 region 2 DIR45_05595 PF08281 Sigma-70, region 4 DIR45_05620 PF07690 Major Facilitator Superfamily DIR45_05625 PF07690 Major Facilitator Superfamily DIR45_05635 PF13538 UvrD-like helicase C-terminal domain DIR45_05660 PF01047 MarR family DIR45_05665 PF12732 YtxH-like protein DIR45_05670 PF01230 HIT domain DIR45_05680 PF00005 ABC transporter DIR45_05685 PF05975 Bacterial ABC transporter protein EcsB DIR45_05690 PF12787 EcsC protein family DIR45_05700 PF17934 Tetracyclin repressor-like, C-terminal domain DIR45_05700 PF00440 Bacterial regulatory proteins, tetR family DIR45_05710 PF03703 Bacterial PH domain DIR45_05760 PF03703 Bacterial PH domain DIR45_05765 PF03703 Bacterial PH domain DIR45_05770 PF03992 Antibiotic biosynthesis monooxygenase DIR45_05775 PF00905 Penicillin binding protein transpeptidase domain DIR45_05775 PF00912 Transglycosylase DIR45_05780 PF01208 Uroporphyrinogen decarboxylase (URO-D) DIR45_05815 PF03965 Penicillinase repressor DIR45_05825 PF17932 Tetracyclin repressor-like, C-terminal domain DIR45_05825 PF00440 Bacterial regulatory proteins, tetR family DIR45_05855 PF00356 Bacterial regulatory proteins, lacI family DIR45_05860 PF14149 YhfH-like protein DIR45_05865 PF12706 Beta-lactamase superfamily domain DIR45_05870 PF10437 Bacterial lipoate protein ligase C-terminus DIR45_05870 PF03099 Biotin/lipoate A/B protein ligase family DIR45_05880 PF00501 AMP-binding enzyme DIR45_05880 PF13193 AMP-binding enzyme C-terminal domain DIR45_05890 PF01520 N-acetylmuramoyl-L-alanine amidase DIR45_05890 PF00395 S-layer homology domain DIR45_05895 PF05593 RHS Repeat DIR45_05910 PF05593 RHS Repeat DIR45_05945 PF02129 X-Pro dipeptidyl-peptidase (S15 family) DIR45_05955 PF00149 Calcineurin-like phosphoesterase DIR45_05960 PF01966 HD domain DIR45_05970 PF04542 Sigma-70 region 2 DIR45_05970 PF08281 Sigma-70, region 4 DIR45_05975 PF12833 Helix-turn-helix domain DIR45_05975 PF06445 GyrI-like small molecule binding domain DIR45_05990 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_05990 PF00512 His Kinase A (phospho-acceptor) domain DIR45_05995 PF00072 Response regulator receiver domain DIR45_05995 PF00486 Transcriptional regulatory protein, C terminal DIR45_06020 PF01435 Peptidase family M48 DIR45_06020 PF16491 CAAX prenyl protease N-terminal, five membrane helices DIR45_06025 PF02743 Cache domain DIR45_06025 PF00672 HAMP domain DIR45_06025 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_06030 PF00892 EamA-like transporter family DIR45_06035 PF03424 Carbohydrate binding domain (family 17/28) DIR45_06035 PF00150 Cellulase (glycosyl hydrolase family 5) DIR45_06035 PF00395 S-layer homology domain DIR45_06045 PF00395 S-layer homology domain DIR45_06050 PF01274 Malate synthase DIR45_06055 PF00463 Isocitrate lyase family DIR45_06065 PF00313 'Cold-shock' DNA-binding domain DIR45_06080 PF06338 ComK protein DIR45_06085 PF09335 SNARE associated Golgi protein DIR45_06090 PF10502 Signal peptidase, peptidase S26 DIR45_06095 PF12705 PD-(D/E)XK nuclease superfamily DIR45_06095 PF13361 UvrD-like helicase C-terminal domain DIR45_06100 PF12705 PD-(D/E)XK nuclease superfamily DIR45_06100 PF00580 UvrD/REP helicase N-terminal domain DIR45_06100 PF13361 UvrD-like helicase C-terminal domain DIR45_06110 PF10676 Spore germination protein gerPA/gerPF DIR45_06115 PF10970 Spore germination protein GerPE DIR45_06125 PF10737 Spore germination protein GerPC DIR45_06130 PF10803 Spore germination GerPB DIR45_06135 PF10676 Spore germination protein gerPA/gerPF DIR45_06145 PF01557 Fumarylacetoacetate (FAA) hydrolase family DIR45_06155 PF00202 Aminotransferase class-III DIR45_06160 PF07457 Protein of unknown function (DUF1516) DIR45_06170 PF00733 Asparagine synthase DIR45_06170 PF13537 Glutamine amidotransferase domain DIR45_06180 PF00199 Catalase DIR45_06180 PF06628 Catalase-related immune-responsive DIR45_06185 PF00909 Ammonium Transporter Family DIR45_06195 PF00128 Alpha amylase, catalytic domain DIR45_06205 PF04461 Protein of unknown function (DUF520) DIR45_06210 PF17783 CvfB-like winged helix domain DIR45_06210 PF13509 S1 domain DIR45_06220 PF00639 PPIC-type PPIASE domain DIR45_06230 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_06230 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_06235 PF12758 Protein of unknown function (DUF3813) DIR45_06255 PF14168 YjzC-like protein DIR45_06260 PF02861 Clp amino terminal domain, pathogenicity island component DIR45_06260 PF17871 AAA lid domain DIR45_06260 PF07724 AAA domain (Cdc48 subfamily) DIR45_06260 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_06260 PF10431 C-terminal, D2-small domain, of ClpB protein DIR45_06280 PF10815 ComZ DIR45_06290 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DIR45_06290 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DIR45_06295 PF00109 Beta-ketoacyl synthase, N-terminal domain DIR45_06295 PF02801 Beta-ketoacyl synthase, C-terminal domain DIR45_06300 PF10026 Predicted Zn-dependent protease (DUF2268) DIR45_06305 PF12227 Protein of unknown function (DUF3603) DIR45_06315 PF00579 tRNA synthetases class I (W and Y) DIR45_06330 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_06335 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_06340 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_06340 PF12911 N-terminal TM domain of oligopeptide transport permease C DIR45_06345 PF00005 ABC transporter DIR45_06345 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_06350 PF00005 ABC transporter DIR45_06350 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_06355 PF01554 MatE DIR45_06360 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_06375 PF03960 ArsC family DIR45_06380 PF03741 Integral membrane protein TerC family DIR45_06385 PF05389 Negative regulator of genetic competence (MecA) DIR45_06390 PF13396 Phospholipase_D-nuclease N-terminal DIR45_06390 PF13091 PLD-like domain DIR45_06400 PF08439 Oligopeptidase F DIR45_06400 PF01432 Peptidase family M3 DIR45_06415 PF01152 Bacterial-like globin DIR45_06420 PF01928 CYTH domain DIR45_06430 PF04607 Region found in RelA / SpoT proteins DIR45_06435 PF01513 ATP-NAD kinase DIR45_06440 PF00849 RNA pseudouridylate synthase DIR45_06450 PF00149 Calcineurin-like phosphoesterase DIR45_06460 PF00535 Glycosyl transferase family 2 DIR45_06465 PF08241 Methyltransferase domain DIR45_06470 PF05711 Macrocin-O-methyltransferase (TylF) DIR45_06500 PF00483 Nucleotidyl transferase DIR45_06505 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase DIR45_06510 PF16363 GDP-mannose 4,6 dehydratase DIR45_06515 PF04321 RmlD substrate binding domain DIR45_06535 PF07098 Protein of unknown function (DUF1360) DIR45_06555 PF00580 UvrD/REP helicase N-terminal domain DIR45_06555 PF13361 UvrD-like helicase C-terminal domain DIR45_06560 PF13673 Acetyltransferase (GNAT) domain DIR45_06570 PF00756 Putative esterase DIR45_06585 PF02368 Bacterial Ig-like domain (group 2) DIR45_06590 PF00474 Sodium:solute symporter family DIR45_06605 PF00591 Glycosyl transferase family, a/b domain DIR45_06605 PF00117 Glutamine amidotransferase class-I DIR45_06605 PF02885 Glycosyl transferase family, helical bundle domain DIR45_06610 PF00591 Glycosyl transferase family, a/b domain DIR45_06610 PF02885 Glycosyl transferase family, helical bundle domain DIR45_06615 PF00218 Indole-3-glycerol phosphate synthase DIR45_06620 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DIR45_06625 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_06640 PF02652 L-lactate permease DIR45_06645 PF10042 Uncharacterized conserved protein (DUF2278) DIR45_06675 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_06675 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_06705 PF02817 e3 binding domain DIR45_06705 PF00364 Biotin-requiring enzyme DIR45_06705 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DIR45_06710 PF00676 Dehydrogenase E1 component DIR45_06710 PF16870 2-oxoglutarate dehydrogenase C-terminal DIR45_06710 PF02779 Transketolase, pyrimidine binding domain DIR45_06715 PF01381 Helix-turn-helix DIR45_06775 PF13649 Methyltransferase domain DIR45_06790 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_06790 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_06800 PF12389 Camelysin metallo-endopeptidase DIR45_06810 PF12389 Camelysin metallo-endopeptidase DIR45_06815 PF08671 Anti-repressor SinI DIR45_06815 PF01381 Helix-turn-helix DIR45_06825 PF05547 Immune inhibitor A peptidase M6 DIR45_06830 PF00171 Aldehyde dehydrogenase family DIR45_06835 PF08402 TOBE domain DIR45_06835 PF00005 ABC transporter DIR45_06840 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_06845 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_06850 PF13416 Bacterial extracellular solute-binding protein DIR45_06860 PF03176 MMPL family DIR45_06870 PF00849 RNA pseudouridylate synthase DIR45_06870 PF01479 S4 domain DIR45_06880 PF00188 Cysteine-rich secretory protein family DIR45_06885 PF13183 4Fe-4S dicluster domain DIR45_06885 PF02754 Cysteine-rich domain DIR45_06890 PF02913 FAD linked oxidases, C-terminal domain DIR45_06890 PF01565 FAD binding domain DIR45_06895 PF05651 Putative sugar diacid recognition DIR45_06895 PF17853 GGDEF-like domain DIR45_06895 PF13556 PucR C-terminal helix-turn-helix domain DIR45_06905 PF00072 Response regulator receiver domain DIR45_06905 PF00486 Transcriptional regulatory protein, C terminal DIR45_06910 PF00672 HAMP domain DIR45_06910 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_06910 PF18698 Histidine kinase sensor domain DIR45_06910 PF00512 His Kinase A (phospho-acceptor) domain DIR45_06910 PF00989 PAS fold DIR45_06915 PF07729 FCD domain DIR45_06915 PF00392 Bacterial regulatory proteins, gntR family DIR45_06920 PF02754 Cysteine-rich domain DIR45_06925 PF02589 LUD domain DIR45_06925 PF11870 Domain of unknown function (DUF3390) DIR45_06925 PF13183 4Fe-4S dicluster domain DIR45_06930 PF02589 LUD domain DIR45_06935 PF01478 Type IV leader peptidase family DIR45_06935 PF06750 Bacterial Peptidase A24 N-terminal domain DIR45_06945 PF01226 Formate/nitrite transporter DIR45_06950 PF03741 Integral membrane protein TerC family DIR45_06960 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_06965 PF01575 MaoC like domain DIR45_06990 PF00561 alpha/beta hydrolase fold DIR45_07000 PF02386 Cation transport protein DIR45_07035 PF13419 Haloacid dehalogenase-like hydrolase DIR45_07040 PF00266 Aminotransferase class-V DIR45_07050 PF00455 DeoR C terminal sensor domain DIR45_07050 PF08220 DeoR-like helix-turn-helix domain DIR45_07070 PF04748 Divergent polysaccharide deacetylase DIR45_07075 PF09388 Spo0E like sporulation regulatory protein DIR45_07080 PF00512 His Kinase A (phospho-acceptor) domain DIR45_07080 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_07080 PF02743 Cache domain DIR45_07085 PF01047 MarR family DIR45_07095 PF12867 DinB superfamily DIR45_07105 PF00512 His Kinase A (phospho-acceptor) domain DIR45_07105 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_07105 PF13426 PAS domain DIR45_07105 PF00989 PAS fold DIR45_07105 PF13188 PAS domain DIR45_07110 PF06508 Queuosine biosynthesis protein QueC DIR45_07115 PF01242 6-pyruvoyl tetrahydropterin synthase DIR45_07120 PF04055 Radical SAM superfamily DIR45_07125 PF14489 QueF-like protein DIR45_07130 PF09953 Uncharacterized protein conserved in bacteria (DUF2187) DIR45_07165 PF07972 NrdI Flavodoxin like DIR45_07185 PF00268 Ribonucleotide reductase, small chain DIR45_07190 PF00392 Bacterial regulatory proteins, gntR family DIR45_07195 PF00005 ABC transporter DIR45_07205 PF00005 ABC transporter DIR45_07225 PF01037 Lrp/AsnC ligand binding domain DIR45_07235 PF00857 Isochorismatase family DIR45_07245 PF02016 LD-carboxypeptidase N-terminal domain DIR45_07245 PF17676 LD-carboxypeptidase C-terminal domain DIR45_07250 PF03060 Nitronate monooxygenase DIR45_07255 PF04914 DltD protein DIR45_07260 PF00550 Phosphopantetheine attachment site DIR45_07265 PF03062 MBOAT, membrane-bound O-acyltransferase family DIR45_07270 PF13193 AMP-binding enzyme C-terminal domain DIR45_07270 PF00501 AMP-binding enzyme DIR45_07280 PF07687 Peptidase dimerisation domain DIR45_07280 PF01546 Peptidase family M20/M25/M40 DIR45_07290 PF00258 Flavodoxin DIR45_07305 PF01636 Phosphotransferase enzyme family DIR45_07330 PF01554 MatE DIR45_07335 PF02673 Bacitracin resistance protein BacA DIR45_07350 PF01047 MarR family DIR45_07360 PF00375 Sodium:dicarboxylate symporter family DIR45_07365 PF02386 Cation transport protein DIR45_07375 PF09579 Sporulation protein YtfJ (Spore_YtfJ) DIR45_07390 PF03698 Uncharacterised protein family (UPF0180) DIR45_07405 PF01063 Amino-transferase class IV DIR45_07410 PF00205 Thiamine pyrophosphate enzyme, central domain DIR45_07410 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_07410 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_07415 PF10369 Small subunit of acetolactate synthase DIR45_07415 PF01842 ACT domain DIR45_07420 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain DIR45_07420 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain DIR45_07425 PF00682 HMGL-like DIR45_07425 PF08502 LeuA allosteric (dimerisation) domain DIR45_07430 PF00180 Isocitrate/isopropylmalate dehydrogenase DIR45_07435 PF00330 Aconitase family (aconitate hydratase) DIR45_07440 PF00694 Aconitase C-terminal domain DIR45_07445 PF13393 Histidyl-tRNA synthetase DIR45_07450 PF01634 ATP phosphoribosyltransferase DIR45_07455 PF00815 Histidinol dehydrogenase DIR45_07460 PF00475 Imidazoleglycerol-phosphate dehydratase DIR45_07465 PF00117 Glutamine amidotransferase class-I DIR45_07470 PF00977 Histidine biosynthesis protein DIR45_07475 PF00977 Histidine biosynthesis protein DIR45_07480 PF01502 Phosphoribosyl-AMP cyclohydrolase DIR45_07485 PF01503 Phosphoribosyl-ATP pyrophosphohydrolase DIR45_07490 PF02811 PHP domain DIR45_07500 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DIR45_07500 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DIR45_07505 PF01066 CDP-alcohol phosphatidyltransferase DIR45_07510 PF00884 Sulfatase DIR45_07520 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DIR45_07520 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DIR45_07530 PF01507 Phosphoadenosine phosphosulfate reductase family DIR45_07535 PF01747 ATP-sulfurylase DIR45_07535 PF14306 PUA-like domain DIR45_07545 PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain DIR45_07545 PF01077 Nitrite and sulphite reductase 4Fe-4S domain DIR45_07555 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases DIR45_07560 PF01903 CbiX DIR45_07575 PF00209 Sodium:neurotransmitter symporter family DIR45_07585 PF00375 Sodium:dicarboxylate symporter family DIR45_07595 PF03553 Na+/H+ antiporter family DIR45_07610 PF09922 Cell wall-active antibiotics response 4TMS YvqF DIR45_07615 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_07615 PF00672 HAMP domain DIR45_07615 PF07730 Histidine kinase DIR45_07620 PF00196 Bacterial regulatory proteins, luxR family DIR45_07620 PF00072 Response regulator receiver domain DIR45_07630 PF05525 Branched-chain amino acid transport protein DIR45_07640 PF08241 Methyltransferase domain DIR45_07665 PF00175 Oxidoreductase NAD-binding domain DIR45_07665 PF00970 Oxidoreductase FAD-binding domain DIR45_07665 PF00042 Globin DIR45_07685 PF01925 Sulfite exporter TauE/SafE DIR45_07690 PF01384 Phosphate transporter family DIR45_07695 PF01865 Protein of unknown function DUF47 DIR45_07700 PF00905 Penicillin binding protein transpeptidase domain DIR45_07700 PF00912 Transglycosylase DIR45_07720 PF01904 Protein of unknown function DUF72 DIR45_07730 PF00589 Phage integrase family DIR45_07735 PF00512 His Kinase A (phospho-acceptor) domain DIR45_07735 PF00989 PAS fold DIR45_07735 PF16736 Single Cache-like DIR45_07735 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_07740 PF01048 Phosphorylase superfamily DIR45_07765 PF09924 Uncharacterised conserved protein (DUF2156) DIR45_07765 PF03706 Lysylphosphatidylglycerol synthase TM region DIR45_07780 PF02777 Iron/manganese superoxide dismutases, C-terminal domain DIR45_07780 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain DIR45_07785 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_07785 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_07790 PF07670 Nucleoside recognition DIR45_07795 PF07670 Nucleoside recognition DIR45_07800 PF00849 RNA pseudouridylate synthase DIR45_07800 PF01479 S4 domain DIR45_07805 PF00578 AhpC/TSA family DIR45_07810 PF05140 ResB-like family DIR45_07815 PF01578 Cytochrome C assembly protein DIR45_07820 PF00486 Transcriptional regulatory protein, C terminal DIR45_07820 PF00072 Response regulator receiver domain DIR45_07825 PF00989 PAS fold DIR45_07825 PF18698 Histidine kinase sensor domain DIR45_07825 PF00512 His Kinase A (phospho-acceptor) domain DIR45_07825 PF00672 HAMP domain DIR45_07825 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_07830 PF01923 Cobalamin adenosyltransferase DIR45_07845 PF12822 ECF transporter, substrate-specific component DIR45_07855 PF14493 Helix-turn-helix domain DIR45_07860 PF00270 DEAD/DEAH box helicase DIR45_07860 PF00271 Helicase conserved C-terminal domain DIR45_07865 PF02517 CPBP intramembrane metalloprotease DIR45_07880 PF02310 B12 binding domain DIR45_07880 PF13411 MerR HTH family regulatory protein DIR45_07880 PF02607 B12 binding domain DIR45_07885 PF05389 Negative regulator of genetic competence (MecA) DIR45_07890 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DIR45_07890 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DIR45_07915 PF17763 Glutaminase/Asparaginase C-terminal domain DIR45_07915 PF00710 Asparaginase, N-terminal DIR45_07925 PF02224 Cytidylate kinase DIR45_07930 PF00575 S1 RNA binding domain DIR45_07935 PF01070 FMN-dependent dehydrogenase DIR45_07940 PF14140 YpzI-like protein DIR45_07950 PF14045 YIEGIA protein DIR45_07960 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal DIR45_07960 PF01926 50S ribosome-binding GTPase DIR45_07965 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DIR45_07965 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DIR45_07975 PF10966 Protein of unknown function (DUF2768) DIR45_07985 PF09547 Stage IV sporulation protein A (spore_IV_A) DIR45_07990 PF00216 Bacterial DNA-binding protein DIR45_07995 PF01227 GTP cyclohydrolase I DIR45_08000 PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DIR45_08005 PF01209 ubiE/COQ5 methyltransferase family DIR45_08010 PF00348 Polyprenyl synthetase DIR45_08015 PF00334 Nucleoside diphosphate kinase DIR45_08020 PF01264 Chorismate synthase DIR45_08025 PF01761 3-dehydroquinate synthase DIR45_08030 PF00155 Aminotransferase class I and II DIR45_08040 PF08864 UPF0302 domain DIR45_08040 PF08858 IDEAL domain DIR45_08045 PF10673 Protein of unknown function (DUF2487) DIR45_08050 PF00355 Rieske [2Fe-2S] domain DIR45_08055 PF00033 Cytochrome b/b6/petB DIR45_08060 PF13442 Cytochrome C oxidase, cbb3-type, subunit III DIR45_08060 PF00032 Cytochrome b(C-terminal)/b6/petD DIR45_08070 PF07187 Protein of unknown function (DUF1405) DIR45_08080 PF09577 Sporulation protein YpjB (SpoYpjB) DIR45_08085 PF04298 Putative neutral zinc metallopeptidase DIR45_08095 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_08095 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_08105 PF03819 MazG nucleotide pyrophosphohydrolase domain DIR45_08110 PF05173 Dihydrodipicolinate reductase, C-terminus DIR45_08110 PF01113 Dihydrodipicolinate reductase, N-terminus DIR45_08115 PF02142 MGS-like domain DIR45_08120 PF02585 GlcNAc-PI de-N-acetylase DIR45_08125 PF13439 Glycosyltransferase Family 4 DIR45_08125 PF00534 Glycosyl transferases group 1 DIR45_08130 PF13735 tRNA nucleotidyltransferase domain 2 putative DIR45_08130 PF01743 Poly A polymerase head domain DIR45_08130 PF12627 Probable RNA and SrmB- binding site of polymerase A DIR45_08135 PF02237 Biotin protein ligase C terminal domain DIR45_08135 PF03099 Biotin/lipoate A/B protein ligase family DIR45_08135 PF08279 HTH domain DIR45_08150 PF02548 Ketopantoate hydroxymethyltransferase DIR45_08155 PF02569 Pantoate-beta-alanine ligase DIR45_08160 PF02261 Aspartate decarboxylase DIR45_08170 PF14084 Protein of unknown function (DUF4264) DIR45_08180 PF00155 Aminotransferase class I and II DIR45_08185 PF07261 Replication initiation and membrane attachment DIR45_08190 PF00730 HhH-GPD superfamily base excision DNA repair protein DIR45_08190 PF00633 Helix-hairpin-helix motif DIR45_08190 PF10576 Iron-sulfur binding domain of endonuclease III DIR45_08200 PF00905 Penicillin binding protein transpeptidase domain DIR45_08200 PF00912 Transglycosylase DIR45_08205 PF03838 Recombination protein U DIR45_08210 PF10720 Protein of unknown function (DUF2515) DIR45_08245 PF06908 YspA SLOG family DIR45_08250 PF05103 DivIVA protein DIR45_08260 PF01170 Putative RNA methylase family UPF0020 DIR45_08260 PF02926 THUMP domain DIR45_08270 PF13307 Helicase C-terminal domain DIR45_08275 PF02074 Carboxypeptidase Taq (M32) metallopeptidase DIR45_08285 PF01636 Phosphotransferase enzyme family DIR45_08290 PF00557 Metallopeptidase family M24 DIR45_08295 PF00156 Phosphoribosyl transferase domain DIR45_08300 PF00860 Permease family DIR45_08305 PF04235 Protein of unknown function (DUF418) DIR45_08315 PF00350 Dynamin family DIR45_08325 PF00583 Acetyltransferase (GNAT) family DIR45_08330 PF10752 Protein of unknown function (DUF2533) DIR45_08335 PF00581 Rhodanese-like domain DIR45_08360 PF03738 Glutathionylspermidine synthase preATP-grasp DIR45_08370 PF00689 Cation transporting ATPase, C-terminus DIR45_08370 PF00690 Cation transporter/ATPase, N-terminus DIR45_08375 PF01367 5'-3' exonuclease, C-terminal SAM fold DIR45_08375 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain DIR45_08405 PF02397 Bacterial sugar transferase DIR45_08420 PF00535 Glycosyl transferase family 2 DIR45_08440 PF13673 Acetyltransferase (GNAT) domain DIR45_08440 PF18014 Acetyltransferase (GNAT) domain DIR45_08460 PF13456 Reverse transcriptase-like DIR45_08465 PF01263 Aldose 1-epimerase DIR45_08490 PF00313 'Cold-shock' DNA-binding domain DIR45_08500 PF01810 LysE type translocator DIR45_08515 PF04341 Protein of unknown function, DUF485 DIR45_08520 PF00474 Sodium:solute symporter family DIR45_08525 PF00202 Aminotransferase class-III DIR45_08540 PF00999 Sodium/hydrogen exchanger family DIR45_08545 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain DIR45_08545 PF17770 Ribonuclease J C-terminal domain DIR45_08545 PF00753 Metallo-beta-lactamase superfamily DIR45_08550 PF06445 GyrI-like small molecule binding domain DIR45_08550 PF13411 MerR HTH family regulatory protein DIR45_08560 PF04239 Protein of unknown function (DUF421) DIR45_08565 PF02698 DUF218 domain DIR45_08575 PF00881 Nitroreductase family DIR45_08620 PF17209 Hfq protein DIR45_08630 PF01618 MotA/TolQ/ExbB proton channel family DIR45_08635 PF00691 OmpA family DIR45_08635 PF13677 Membrane MotB of proton-channel complex MotA/MotB DIR45_08640 PF00072 Response regulator receiver domain DIR45_08650 PF01052 Type III flagellar switch regulator (C-ring) FliN C-term DIR45_08650 PF04509 CheC-like family DIR45_08665 PF01739 CheR methyltransferase, SAM binding domain DIR45_08665 PF03705 CheR methyltransferase, all-alpha domain DIR45_08685 PF00460 Flagella basal body rod protein DIR45_08685 PF06429 Flagellar basal body rod FlgEFG protein C-terminal DIR45_08710 PF00460 Flagella basal body rod protein DIR45_08715 PF06429 Flagellar basal body rod FlgEFG protein C-terminal DIR45_08715 PF00460 Flagella basal body rod protein DIR45_08720 PF02049 Flagellar hook-basal body complex protein FliE DIR45_08730 PF14842 FliG N-terminal domain DIR45_08730 PF14841 FliG middle domain DIR45_08730 PF01706 FliG C-terminal domain DIR45_08740 PF18269 T3SS EscN ATPase C-terminal domain DIR45_08740 PF02874 ATP synthase alpha/beta family, beta-barrel domain DIR45_08740 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain DIR45_08765 PF06429 Flagellar basal body rod FlgEFG protein C-terminal DIR45_08765 PF00460 Flagella basal body rod protein DIR45_08765 PF07559 Flagellar basal body protein FlaE DIR45_08785 PF01584 CheW-like domain DIR45_08785 PF00072 Response regulator receiver domain DIR45_08790 PF12181 DNA binding domain of the motility gene repressor (MogR) DIR45_08795 PF00535 Glycosyl transferase family 2 DIR45_08835 PF13181 Tetratricopeptide repeat DIR45_08835 PF00535 Glycosyl transferase family 2 DIR45_08850 PF00700 Bacterial flagellin C-terminal helical region DIR45_08850 PF00669 Bacterial flagellin N-terminal helical region DIR45_08855 PF01464 Transglycosylase SLT domain DIR45_08870 PF01052 Type III flagellar switch regulator (C-ring) FliN C-term DIR45_08870 PF04509 CheC-like family DIR45_08880 PF00813 FliP family DIR45_08885 PF01313 Bacterial export proteins, family 3 DIR45_08895 PF01312 FlhB HrpN YscU SpaS Family DIR45_08900 PF00771 FHIPEP family DIR45_08905 PF00448 SRP54-type protein, GTPase domain DIR45_08910 PF06429 Flagellar basal body rod FlgEFG protein C-terminal DIR45_08910 PF00460 Flagella basal body rod protein DIR45_08915 PF01411 tRNA synthetases class II (A) DIR45_08915 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain DIR45_08915 PF02272 DHHA1 domain DIR45_08940 PF17932 Tetracyclin repressor-like, C-terminal domain DIR45_08940 PF00440 Bacterial regulatory proteins, tetR family DIR45_08945 PF17329 Family of unknown function (DUF5367) DIR45_08960 PF03992 Antibiotic biosynthesis monooxygenase DIR45_08965 PF08141 Small acid-soluble spore protein H family DIR45_08990 PF08402 TOBE domain DIR45_08990 PF00005 ABC transporter DIR45_09000 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_09005 PF00753 Metallo-beta-lactamase superfamily DIR45_09005 PF12706 Beta-lactamase superfamily domain DIR45_09015 PF10787 Uncharacterised protein from bacillus cereus group DIR45_09035 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_09035 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_09045 PF00300 Histidine phosphatase superfamily (branch 1) DIR45_09075 PF00733 Asparagine synthase DIR45_09075 PF13537 Glutamine amidotransferase domain DIR45_09095 PF01545 Cation efflux family DIR45_09095 PF16916 Dimerisation domain of Zinc Transporter DIR45_09105 PF00392 Bacterial regulatory proteins, gntR family DIR45_09105 PF07729 FCD domain DIR45_09110 PF00892 EamA-like transporter family DIR45_09115 PF02492 CobW/HypB/UreG, nucleotide-binding domain DIR45_09115 PF07683 Cobalamin synthesis protein cobW C-terminal domain DIR45_09125 PF03773 Predicted permease DIR45_09135 PF00535 Glycosyl transferase family 2 DIR45_09140 PF03553 Na+/H+ antiporter family DIR45_09145 PF10415 Fumarase C C-terminus DIR45_09145 PF00206 Lyase DIR45_09175 PF03575 Peptidase family S51 DIR45_09195 PF02683 Cytochrome C biogenesis protein transmembrane region DIR45_09200 PF00578 AhpC/TSA family DIR45_09225 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_09230 PF04286 Protein of unknown function (DUF445) DIR45_09260 PF00196 Bacterial regulatory proteins, luxR family DIR45_09260 PF00072 Response regulator receiver domain DIR45_09265 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_09265 PF07730 Histidine kinase DIR45_09265 PF13185 GAF domain DIR45_09265 PF13492 GAF domain DIR45_09270 PF00005 ABC transporter DIR45_09285 PF13091 PLD-like domain DIR45_09290 PF00696 Amino acid kinase family DIR45_09295 PF00375 Sodium:dicarboxylate symporter family DIR45_09300 PF10415 Fumarase C C-terminus DIR45_09300 PF00206 Lyase DIR45_09305 PF03949 Malic enzyme, NAD binding domain DIR45_09305 PF00390 Malic enzyme, N-terminal domain DIR45_09310 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_09315 PF00072 Response regulator receiver domain DIR45_09315 PF08664 YcbB domain DIR45_09320 PF00271 Helicase conserved C-terminal domain DIR45_09320 PF00176 SNF2 family N-terminal domain DIR45_09320 PF04434 SWIM zinc finger DIR45_09340 PF03590 Aspartate-ammonia ligase DIR45_09360 PF00696 Amino acid kinase family DIR45_09360 PF13840 ACT domain DIR45_09375 PF13761 Domain of unknown function (DUF4166) DIR45_09380 PF14158 YndJ-like protein DIR45_09390 PF13205 Bacterial Ig-like domain DIR45_09390 PF00395 S-layer homology domain DIR45_09390 PF02368 Bacterial Ig-like domain (group 2) DIR45_09400 PF07690 Major Facilitator Superfamily DIR45_09415 PF02554 Carbon starvation protein CstA DIR45_09420 PF03976 Polyphosphate kinase 2 (PPK2) DIR45_09430 PF07690 Major Facilitator Superfamily DIR45_09435 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DIR45_09435 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DIR45_09445 PF01926 50S ribosome-binding GTPase DIR45_09445 PF13167 GTP-binding GTPase N-terminal DIR45_09445 PF16360 GTP-binding GTPase Middle Region DIR45_09460 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_09475 PF01943 Polysaccharide biosynthesis protein DIR45_09475 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_09480 PF00209 Sodium:neurotransmitter symporter family DIR45_09485 PF03422 Carbohydrate binding module (family 6) DIR45_09485 PF00457 Glycosyl hydrolases family 11 DIR45_09485 PF01522 Polysaccharide deacetylase DIR45_09495 PF04239 Protein of unknown function (DUF421) DIR45_09515 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase DIR45_09515 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DIR45_09535 PF01625 Peptide methionine sulfoxide reductase DIR45_09545 PF01063 Amino-transferase class IV DIR45_09550 PF00205 Thiamine pyrophosphate enzyme, central domain DIR45_09550 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_09550 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_09555 PF10369 Small subunit of acetolactate synthase DIR45_09560 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain DIR45_09560 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain DIR45_09565 PF00920 Dehydratase family DIR45_09570 PF00585 C-terminal regulatory domain of Threonine dehydratase DIR45_09570 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_09600 PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase DIR45_09610 PF00072 Response regulator receiver domain DIR45_09610 PF04397 LytTr DNA-binding domain DIR45_09615 PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain DIR45_09615 PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain DIR45_09630 PF01979 Amidohydrolase family DIR45_09635 PF13026 Protein of unknown function (DUF3887) DIR45_09635 PF12146 Serine aminopeptidase, S33 DIR45_09640 PF00005 ABC transporter DIR45_09645 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_09680 PF13186 Iron-sulfur cluster-binding domain DIR45_09680 PF04055 Radical SAM superfamily DIR45_09685 PF13302 Acetyltransferase (GNAT) domain DIR45_09690 PF00072 Response regulator receiver domain DIR45_09690 PF00486 Transcriptional regulatory protein, C terminal DIR45_09695 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_09695 PF00512 His Kinase A (phospho-acceptor) domain DIR45_09705 PF01566 Natural resistance-associated macrophage protein DIR45_09720 PF02558 Ketopantoate reductase PanE/ApbA DIR45_09720 PF08546 Ketopantoate reductase PanE/ApbA C terminal DIR45_09740 PF05791 Bacillus haemolytic enterotoxin (HBL) DIR45_09745 PF05791 Bacillus haemolytic enterotoxin (HBL) DIR45_09755 PF04198 Putative sugar-binding domain DIR45_09760 PF01791 DeoC/LacD family aldolase DIR45_09765 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_09765 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_09770 PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain DIR45_09770 PF00591 Glycosyl transferase family, a/b domain DIR45_09770 PF02885 Glycosyl transferase family, helical bundle domain DIR45_09775 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region DIR45_09785 PF05979 Bacterial protein of unknown function (DUF896) DIR45_09805 PF00557 Metallopeptidase family M24 DIR45_09805 PF05195 Aminopeptidase P, N-terminal domain DIR45_09810 PF07731 Multicopper oxidase DIR45_09810 PF07732 Multicopper oxidase DIR45_09815 PF01551 Peptidase family M23 DIR45_09840 PF02525 Flavodoxin-like fold DIR45_09855 PF05425 Copper resistance protein D DIR45_09855 PF13115 YtkA-like DIR45_09855 PF04234 CopC domain DIR45_09860 PF07987 Domain of unkown function (DUF1775) DIR45_09870 PF00892 EamA-like transporter family DIR45_09875 PF03466 LysR substrate binding domain DIR45_09875 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_09880 PF02082 Transcriptional regulator DIR45_09885 PF01323 DSBA-like thioredoxin domain DIR45_09890 PF00881 Nitroreductase family DIR45_09900 PF01425 Amidase DIR45_09905 PF01594 AI-2E family transporter DIR45_09910 PF00056 lactate/malate dehydrogenase, NAD binding domain DIR45_09910 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain DIR45_09915 PF01593 Flavin containing amine oxidoreductase DIR45_09920 PF07683 Cobalamin synthesis protein cobW C-terminal domain DIR45_09920 PF02492 CobW/HypB/UreG, nucleotide-binding domain DIR45_09935 PF00501 AMP-binding enzyme DIR45_09935 PF13193 AMP-binding enzyme C-terminal domain DIR45_09940 PF01575 MaoC like domain DIR45_09945 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DIR45_09945 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DIR45_09960 PF12399 Branched-chain amino acid ATP-binding cassette transporter DIR45_09960 PF00005 ABC transporter DIR45_09965 PF00005 ABC transporter DIR45_09970 PF02653 Branched-chain amino acid transport system / permease component DIR45_09980 PF03466 LysR substrate binding domain DIR45_09980 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_09990 PF14552 Tautomerase enzyme DIR45_10000 PF01047 MarR family DIR45_10010 PF01654 Cytochrome bd terminal oxidase subunit I DIR45_10015 PF02322 Cytochrome bd terminal oxidase subunit II DIR45_10020 PF00005 ABC transporter DIR45_10020 PF00664 ABC transporter transmembrane region DIR45_10025 PF00664 ABC transporter transmembrane region DIR45_10025 PF00005 ABC transporter DIR45_10040 PF02016 LD-carboxypeptidase N-terminal domain DIR45_10040 PF17676 LD-carboxypeptidase C-terminal domain DIR45_10045 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_10045 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_10060 PF01476 LysM domain DIR45_10060 PF00877 NlpC/P60 family DIR45_10075 PF00072 Response regulator receiver domain DIR45_10075 PF00486 Transcriptional regulatory protein, C terminal DIR45_10090 PF00106 short chain dehydrogenase DIR45_10100 PF04439 Streptomycin adenylyltransferase DIR45_10105 PF01522 Polysaccharide deacetylase DIR45_10105 PF18627 Peptidoglycan GlcNAc deacetylase N-terminal domain DIR45_10130 PF01842 ACT domain DIR45_10130 PF00742 Homoserine dehydrogenase DIR45_10130 PF03447 Homoserine dehydrogenase, NAD binding domain DIR45_10135 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_10140 PF08544 GHMP kinases C terminal DIR45_10140 PF00288 GHMP kinases N terminal domain DIR45_10155 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_10165 PF00072 Response regulator receiver domain DIR45_10165 PF00486 Transcriptional regulatory protein, C terminal DIR45_10170 PF16736 Single Cache-like DIR45_10170 PF00989 PAS fold DIR45_10170 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_10170 PF00512 His Kinase A (phospho-acceptor) domain DIR45_10175 PF01522 Polysaccharide deacetylase DIR45_10185 PF02308 MgtC family DIR45_10190 PF00583 Acetyltransferase (GNAT) family DIR45_10195 PF04183 IucA / IucC family DIR45_10195 PF06276 Ferric iron reductase FhuF-like transporter DIR45_10200 PF06276 Ferric iron reductase FhuF-like transporter DIR45_10200 PF04183 IucA / IucC family DIR45_10205 PF13193 AMP-binding enzyme C-terminal domain DIR45_10205 PF00501 AMP-binding enzyme DIR45_10220 PF01261 Xylose isomerase-like TIM barrel DIR45_10225 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_10230 PF07690 Major Facilitator Superfamily DIR45_10235 PF01810 LysE type translocator DIR45_10250 PF01734 Patatin-like phospholipase DIR45_10275 PF13344 Haloacid dehalogenase-like hydrolase DIR45_10275 PF00293 NUDIX domain DIR45_10280 PF02540 NAD synthase DIR45_10285 PF02687 FtsX-like permease family DIR45_10290 PF18277 AbrB C-terminal domain DIR45_10290 PF04014 Antidote-toxin recognition MazE, bacterial antitoxin DIR45_10295 PF00082 Subtilase family DIR45_10300 PF01022 Bacterial regulatory protein, arsR family DIR45_10305 PF00248 Aldo/keto reductase family DIR45_10335 PF03193 RsgA GTPase DIR45_10340 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_10340 PF00672 HAMP domain DIR45_10340 PF02743 Cache domain DIR45_10365 PF00210 Ferritin-like domain DIR45_10380 PF00296 Luciferase-like monooxygenase DIR45_10390 PF01593 Flavin containing amine oxidoreductase DIR45_10400 PF00248 Aldo/keto reductase family DIR45_10405 PF02492 CobW/HypB/UreG, nucleotide-binding domain DIR45_10405 PF07683 Cobalamin synthesis protein cobW C-terminal domain DIR45_10410 PF00583 Acetyltransferase (GNAT) family DIR45_10490 PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DIR45_10490 PF01297 Zinc-uptake complex component A periplasmic DIR45_10500 PF13460 NAD(P)H-binding DIR45_10505 PF00724 NADH:flavin oxidoreductase / NADH oxidase family DIR45_10510 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain DIR45_10510 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DIR45_10520 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_10525 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_10535 PF00300 Histidine phosphatase superfamily (branch 1) DIR45_10545 PF08757 CotH kinase protein DIR45_10550 PF00293 NUDIX domain DIR45_10555 PF09335 SNARE associated Golgi protein DIR45_10560 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_10560 PF01943 Polysaccharide biosynthesis protein DIR45_10570 PF03773 Predicted permease DIR45_10575 PF09323 Domain of unknown function (DUF1980) DIR45_10580 PF03061 Thioesterase superfamily DIR45_10590 PF13091 PLD-like domain DIR45_10590 PF13396 Phospholipase_D-nuclease N-terminal DIR45_10605 PF13460 NAD(P)H-binding DIR45_10610 PF04306 Protein of unknown function (DUF456) DIR45_10615 PF00571 CBS domain DIR45_10615 PF03471 Transporter associated domain DIR45_10615 PF01595 Cyclin M transmembrane N-terminal domain DIR45_10630 PF05525 Branched-chain amino acid transport protein DIR45_10635 PF01588 Putative tRNA binding domain DIR45_10655 PF07454 Stage II sporulation protein P (SpoIIP) DIR45_10665 PF02557 D-alanyl-D-alanine carboxypeptidase DIR45_10675 PF01425 Amidase DIR45_10680 PF07690 Major Facilitator Superfamily DIR45_10690 PF01145 SPFH domain / Band 7 family DIR45_10695 PF00300 Histidine phosphatase superfamily (branch 1) DIR45_10710 PF00842 Alanine racemase, C-terminal domain DIR45_10710 PF01168 Alanine racemase, N-terminal domain DIR45_10730 PF00201 UDP-glucoronosyl and UDP-glucosyl transferase DIR45_10735 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_10735 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_10740 PF00155 Aminotransferase class I and II DIR45_10740 PF00392 Bacterial regulatory proteins, gntR family DIR45_10770 PF00583 Acetyltransferase (GNAT) family DIR45_10830 PF09579 Sporulation protein YtfJ (Spore_YtfJ) DIR45_10855 PF01209 ubiE/COQ5 methyltransferase family DIR45_10860 PF01268 Formate--tetrahydrofolate ligase DIR45_10870 PF00271 Helicase conserved C-terminal domain DIR45_10870 PF00270 DEAD/DEAH box helicase DIR45_10875 PF01261 Xylose isomerase-like TIM barrel DIR45_10880 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_10890 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_10890 PF00107 Zinc-binding dehydrogenase DIR45_10895 PF08281 Sigma-70, region 4 DIR45_10895 PF04542 Sigma-70 region 2 DIR45_10920 PF00255 Glutathione peroxidase DIR45_10925 PF13559 Domain of unknown function (DUF4129) DIR45_10925 PF11992 Domain of unknown function (DUF3488) DIR45_10925 PF01841 Transglutaminase-like superfamily DIR45_10930 PF01882 Protein of unknown function DUF58 DIR45_10935 PF17863 AAA lid domain DIR45_10935 PF07726 ATPase family associated with various cellular activities (AAA) DIR45_10950 PF00384 Molybdopterin oxidoreductase DIR45_10950 PF14710 Respiratory nitrate reductase alpha N-terminal DIR45_10950 PF01568 Molydopterin dinucleotide binding domain DIR45_10955 PF13247 4Fe-4S dicluster domain DIR45_10955 PF14711 Respiratory nitrate reductase beta C-terminal DIR45_10960 PF02613 Nitrate reductase delta subunit DIR45_10965 PF02665 Nitrate reductase gamma subunit DIR45_10970 PF00392 Bacterial regulatory proteins, gntR family DIR45_10970 PF00155 Aminotransferase class I and II DIR45_10975 PF00005 ABC transporter DIR45_10985 PF00325 Bacterial regulatory proteins, crp family DIR45_10985 PF00027 Cyclic nucleotide-binding domain DIR45_10990 PF06463 Molybdenum Cofactor Synthesis C DIR45_10990 PF04055 Radical SAM superfamily DIR45_10995 PF00899 ThiF family DIR45_11000 PF00994 Probable molybdopterin binding domain DIR45_11000 PF03454 MoeA C-terminal region (domain IV) DIR45_11000 PF03453 MoeA N-terminal region (domain I and II) DIR45_11005 PF02391 MoaE protein DIR45_11015 PF07690 Major Facilitator Superfamily DIR45_11040 PF01903 CbiX DIR45_11045 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases DIR45_11050 PF00355 Rieske [2Fe-2S] domain DIR45_11055 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_11055 PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain DIR45_11055 PF04324 BFD-like [2Fe-2S] binding domain DIR45_11055 PF18267 Rubredoxin NAD+ reductase C-terminal domain DIR45_11055 PF01077 Nitrite and sulphite reductase 4Fe-4S domain DIR45_11060 PF01814 Hemerythrin HHE cation binding domain DIR45_11060 PF04405 Domain of Unknown function (DUF542) DIR45_11095 PF04232 Stage V sporulation protein S (SpoVS) DIR45_11115 PF01510 N-acetylmuramoyl-L-alanine amidase DIR45_11130 PF01966 HD domain DIR45_11135 PF12848 ABC transporter DIR45_11135 PF16326 ABC transporter C-terminal domain DIR45_11135 PF00005 ABC transporter DIR45_11150 PF00436 Single-strand binding protein family DIR45_11155 PF00440 Bacterial regulatory proteins, tetR family DIR45_11165 PF13769 Virulence factor DIR45_11165 PF08712 Scaffold protein Nfu/NifU N terminal DIR45_11175 PF06491 Disulphide isomerase DIR45_11180 PF04445 Putative SAM-dependent methyltransferase DIR45_11185 PF00750 tRNA synthetases class I (R) DIR45_11185 PF05746 DALR anticodon binding domain DIR45_11185 PF03485 Arginyl tRNA synthetase N terminal domain DIR45_11215 PF00133 tRNA synthetases class I (I, L, M and V) DIR45_11215 PF08264 Anticodon-binding domain of tRNA DIR45_11235 PF01225 Mur ligase family, catalytic domain DIR45_11235 PF02875 Mur ligase family, glutamate ligase domain DIR45_11235 PF08245 Mur ligase middle domain DIR45_11240 PF01336 OB-fold nucleic acid binding domain DIR45_11240 PF00152 tRNA synthetases class II (D, K and N) DIR45_11355 PF02595 Glycerate kinase family DIR45_11360 PF00939 Sodium:sulfate symporter transmembrane region DIR45_11365 PF00072 Response regulator receiver domain DIR45_11365 PF00486 Transcriptional regulatory protein, C terminal DIR45_11370 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_11370 PF00512 His Kinase A (phospho-acceptor) domain DIR45_11370 PF00672 HAMP domain DIR45_11385 PF00209 Sodium:neurotransmitter symporter family DIR45_11400 PF10997 Alternate to MurJ DIR45_11405 PF13419 Haloacid dehalogenase-like hydrolase DIR45_11415 PF00465 Iron-containing alcohol dehydrogenase DIR45_11420 PF01177 Asp/Glu/Hydantoin racemase DIR45_11425 PF01980 tRNA-methyltransferase O DIR45_11430 PF00583 Acetyltransferase (GNAT) family DIR45_11445 PF00005 ABC transporter DIR45_11455 PF14005 YpjP-like protein DIR45_11460 PF13419 Haloacid dehalogenase-like hydrolase DIR45_11480 PF00144 Beta-lactamase DIR45_11480 PF07930 D-aminopeptidase, domain B DIR45_11485 PF00303 Thymidylate synthase DIR45_11490 PF00186 Dihydrofolate reductase DIR45_11495 PF00905 Penicillin binding protein transpeptidase domain DIR45_11495 PF05223 NTF2-like N-terminal transpeptidase domain DIR45_11495 PF03717 Penicillin-binding Protein dimerisation domain DIR45_11500 PF02525 Flavodoxin-like fold DIR45_11505 PF01553 Acyltransferase DIR45_11510 PF03006 Haemolysin-III related DIR45_11515 PF02416 mttA/Hcf106 family DIR45_11520 PF00902 Sec-independent protein translocase protein (TatC) DIR45_11535 PF02645 Uncharacterised protein, DegV family COG1307 DIR45_11545 PF02630 SCO1/SenC DIR45_11550 PF00011 Hsp20/alpha crystallin family DIR45_11555 PF13537 Glutamine amidotransferase domain DIR45_11555 PF00733 Asparagine synthase DIR45_11575 PF01497 Periplasmic binding protein DIR45_11580 PF01063 Amino-transferase class IV DIR45_11585 PF00881 Nitroreductase family DIR45_11605 PF00293 NUDIX domain DIR45_11610 PF00011 Hsp20/alpha crystallin family DIR45_11615 PF00924 Mechanosensitive ion channel DIR45_11620 PF07730 Histidine kinase DIR45_11620 PF13185 GAF domain DIR45_11625 PF00196 Bacterial regulatory proteins, luxR family DIR45_11625 PF00072 Response regulator receiver domain DIR45_11635 PF00107 Zinc-binding dehydrogenase DIR45_11635 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_11650 PF00144 Beta-lactamase DIR45_11665 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_11665 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_11670 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_11670 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_11685 PF03358 NADPH-dependent FMN reductase DIR45_11700 PF00005 ABC transporter DIR45_11700 PF00571 CBS domain DIR45_11705 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_11710 PF13520 Amino acid permease DIR45_11740 PF00571 CBS domain DIR45_11740 PF01595 Cyclin M transmembrane N-terminal domain DIR45_11740 PF03471 Transporter associated domain DIR45_11745 PF00171 Aldehyde dehydrogenase family DIR45_11750 PF07997 Protein of unknown function (DUF1694) DIR45_11755 PF09385 Histidine kinase N terminal DIR45_11770 PF00202 Aminotransferase class-III DIR45_11775 PF01144 Coenzyme A transferase DIR45_11780 PF01144 Coenzyme A transferase DIR45_11785 PF07687 Peptidase dimerisation domain DIR45_11785 PF01546 Peptidase family M20/M25/M40 DIR45_11790 PF00583 Acetyltransferase (GNAT) family DIR45_11795 PF02954 Bacterial regulatory protein, Fis family DIR45_11795 PF13426 PAS domain DIR45_11795 PF00158 Sigma-54 interaction domain DIR45_11805 PF12544 Lysine-2,3-aminomutase DIR45_11810 PF14122 YokU-like protein, putative antitoxin DIR45_11815 PF06855 YozE SAM-like fold DIR45_11830 PF14162 YozD-like protein DIR45_11845 PF07070 SpoOM protein DIR45_11850 PF01569 PAP2 superfamily DIR45_11855 PF01545 Cation efflux family DIR45_11855 PF16916 Dimerisation domain of Zinc Transporter DIR45_11860 PF00085 Thioredoxin DIR45_11875 PF04740 LXG domain of WXG superfamily DIR45_11875 PF14436 Bacterial EndoU nuclease DIR45_11880 PF03424 Carbohydrate binding domain (family 17/28) DIR45_11880 PF00395 S-layer homology domain DIR45_11880 PF00150 Cellulase (glycosyl hydrolase family 5) DIR45_11890 PF04471 Restriction endonuclease DIR45_12030 PF10676 Spore germination protein gerPA/gerPF DIR45_12050 PF00912 Transglycosylase DIR45_12050 PF00905 Penicillin binding protein transpeptidase domain DIR45_12055 PF07690 Major Facilitator Superfamily DIR45_12060 PF01521 Iron-sulphur cluster biosynthesis DIR45_12065 PF00285 Citrate synthase, C-terminal domain DIR45_12070 PF03972 MmgE/PrpD family DIR45_12080 PF00441 Acyl-CoA dehydrogenase, C-terminal domain DIR45_12080 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_12080 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_12085 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase DIR45_12085 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DIR45_12090 PF00171 Aldehyde dehydrogenase family DIR45_12095 PF01810 LysE type translocator DIR45_12100 PF00378 Enoyl-CoA hydratase/isomerase DIR45_12110 PF10763 Protein of unknown function (DUF2584) DIR45_12115 PF00149 Calcineurin-like phosphoesterase DIR45_12115 PF12320 Type 5 capsule protein repressor C-terminal domain DIR45_12120 PF13476 AAA domain DIR45_12135 PF01022 Bacterial regulatory protein, arsR family DIR45_12155 PF07690 Major Facilitator Superfamily DIR45_12165 PF00106 short chain dehydrogenase DIR45_12170 PF00425 chorismate binding enzyme DIR45_12175 PF00501 AMP-binding enzyme DIR45_12175 PF13193 AMP-binding enzyme C-terminal domain DIR45_12180 PF00550 Phosphopantetheine attachment site DIR45_12180 PF00857 Isochorismatase family DIR45_12190 PF03621 MbtH-like protein DIR45_12195 PF07690 Major Facilitator Superfamily DIR45_12210 PF00216 Bacterial DNA-binding protein DIR45_12220 PF05163 DinB family DIR45_12225 PF00082 Subtilase family DIR45_12245 PF16291 Domain of unknown function (DUF4937 DIR45_12250 PF01479 S4 domain DIR45_12250 PF00849 RNA pseudouridylate synthase DIR45_12255 PF02824 TGS domain DIR45_12255 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_12255 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain DIR45_12255 PF03129 Anticodon binding domain DIR45_12275 PF12146 Serine aminopeptidase, S33 DIR45_12280 PF07690 Major Facilitator Superfamily DIR45_12300 PF13649 Methyltransferase domain DIR45_12345 PF00753 Metallo-beta-lactamase superfamily DIR45_12345 PF16123 Hydroxyacylglutathione hydrolase C-terminus DIR45_12355 PF03176 MMPL family DIR45_12365 PF00302 Chloramphenicol acetyltransferase DIR45_12380 PF00583 Acetyltransferase (GNAT) family DIR45_12420 PF13302 Acetyltransferase (GNAT) domain DIR45_12430 PF00313 'Cold-shock' DNA-binding domain DIR45_12500 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_12500 PF03466 LysR substrate binding domain DIR45_12505 PF02774 Semialdehyde dehydrogenase, dimerisation domain DIR45_12505 PF01118 Semialdehyde dehydrogenase, NAD binding domain DIR45_12520 PF03466 LysR substrate binding domain DIR45_12520 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_12525 PF03473 MOSC domain DIR45_12525 PF03475 3-alpha domain DIR45_12540 PF00005 ABC transporter DIR45_12540 PF00664 ABC transporter transmembrane region DIR45_12545 PF00664 ABC transporter transmembrane region DIR45_12545 PF00005 ABC transporter DIR45_12560 PF01810 LysE type translocator DIR45_12565 PF07883 Cupin domain DIR45_12565 PF01381 Helix-turn-helix DIR45_12590 PF00890 FAD binding domain DIR45_12595 PF04542 Sigma-70 region 2 DIR45_12595 PF12680 SnoaL-like domain DIR45_12595 PF08281 Sigma-70, region 4 DIR45_12625 PF02638 Glycosyl hydrolase-like 10 DIR45_12640 PF02378 Phosphotransferase system, EIIC DIR45_12650 PF03702 Anhydro-N-acetylmuramic acid kinase DIR45_12655 PF01869 BadF/BadG/BcrA/BcrD ATPase family DIR45_12660 PF02660 Glycerol-3-phosphate acyltransferase DIR45_12665 PF00266 Aminotransferase class-V DIR45_12670 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_12695 PF16123 Hydroxyacylglutathione hydrolase C-terminus DIR45_12695 PF00753 Metallo-beta-lactamase superfamily DIR45_12710 PF00271 Helicase conserved C-terminal domain DIR45_12710 PF00270 DEAD/DEAH box helicase DIR45_12725 PF00440 Bacterial regulatory proteins, tetR family DIR45_12725 PF17932 Tetracyclin repressor-like, C-terminal domain DIR45_12740 PF00005 ABC transporter DIR45_12740 PF02687 FtsX-like permease family DIR45_12740 PF12704 MacB-like periplasmic core domain DIR45_12745 PF03848 Tellurite resistance protein TehB DIR45_12745 PF09313 Domain of unknown function (DUF1971) DIR45_12755 PF08241 Methyltransferase domain DIR45_12760 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_12760 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_12760 PF00205 Thiamine pyrophosphate enzyme, central domain DIR45_12765 PF12802 MarR family DIR45_12770 PF00300 Histidine phosphatase superfamily (branch 1) DIR45_12780 PF14171 Toxin SpoIISA, type II toxin-antitoxin system DIR45_12815 PF07687 Peptidase dimerisation domain DIR45_12815 PF01546 Peptidase family M20/M25/M40 DIR45_12835 PF04542 Sigma-70 region 2 DIR45_12835 PF08281 Sigma-70, region 4 DIR45_12845 PF03717 Penicillin-binding Protein dimerisation domain DIR45_12845 PF00905 Penicillin binding protein transpeptidase domain DIR45_12865 PF00356 Bacterial regulatory proteins, lacI family DIR45_12875 PF01408 Oxidoreductase family, NAD-binding Rossmann fold DIR45_12875 PF02894 Oxidoreductase family, C-terminal alpha/beta domain DIR45_12880 PF00294 pfkB family carbohydrate kinase DIR45_12885 PF00171 Aldehyde dehydrogenase family DIR45_12890 PF00205 Thiamine pyrophosphate enzyme, central domain DIR45_12890 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_12890 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_12895 PF01261 Xylose isomerase-like TIM barrel DIR45_12900 PF01116 Fructose-bisphosphate aldolase class-II DIR45_12920 PF02872 5'-nucleotidase, C-terminal domain DIR45_12920 PF00149 Calcineurin-like phosphoesterase DIR45_12930 PF18801 response regulator aspartate phosphatase H, N terminal DIR45_12935 PF01381 Helix-turn-helix DIR45_12950 PF02557 D-alanyl-D-alanine carboxypeptidase DIR45_12960 PF00395 S-layer homology domain DIR45_12960 PF01520 N-acetylmuramoyl-L-alanine amidase DIR45_12970 PF00440 Bacterial regulatory proteins, tetR family DIR45_12985 PF03707 Bacterial signalling protein N terminal repeat DIR45_12985 PF00563 EAL domain DIR45_12985 PF00990 Diguanylate cyclase, GGDEF domain DIR45_12990 PF13302 Acetyltransferase (GNAT) domain DIR45_13010 PF00581 Rhodanese-like domain DIR45_13025 PF00005 ABC transporter DIR45_13035 PF00440 Bacterial regulatory proteins, tetR family DIR45_13035 PF08359 YsiA-like protein, C-terminal region DIR45_13055 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_13055 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_13055 PF00441 Acyl-CoA dehydrogenase, C-terminal domain DIR45_13060 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain DIR45_13060 PF00289 Biotin carboxylase, N-terminal domain DIR45_13060 PF02785 Biotin carboxylase C-terminal domain DIR45_13065 PF00364 Biotin-requiring enzyme DIR45_13070 PF00682 HMGL-like DIR45_13075 PF00378 Enoyl-CoA hydratase/isomerase DIR45_13080 PF01039 Carboxyl transferase domain DIR45_13085 PF00501 AMP-binding enzyme DIR45_13085 PF13193 AMP-binding enzyme C-terminal domain DIR45_13085 PF16177 Acetyl-coenzyme A synthetase N-terminus DIR45_13095 PF00583 Acetyltransferase (GNAT) family DIR45_13100 PF00485 Phosphoribulokinase / Uridine kinase family DIR45_13110 PF05163 DinB family DIR45_13115 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_13115 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_13120 PF00512 His Kinase A (phospho-acceptor) domain DIR45_13120 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_13125 PF00486 Transcriptional regulatory protein, C terminal DIR45_13125 PF00072 Response regulator receiver domain DIR45_13130 PF01966 HD domain DIR45_13135 PF13021 Domain of unknown function (DUF3885) DIR45_13140 PF01048 Phosphorylase superfamily DIR45_13180 PF17755 UvrA DNA-binding domain DIR45_13180 PF17755 UvrA DNA-binding domain DIR45_13180 PF17760 UvrA interaction domain DIR45_13180 PF17760 UvrA interaction domain DIR45_13195 PF00144 Beta-lactamase DIR45_13200 PF09278 MerR, DNA binding DIR45_13200 PF00376 MerR family regulatory protein DIR45_13205 PF07690 Major Facilitator Superfamily DIR45_13225 PF01636 Phosphotransferase enzyme family DIR45_13230 PF12833 Helix-turn-helix domain DIR45_13245 PF00155 Aminotransferase class I and II DIR45_13245 PF00392 Bacterial regulatory proteins, gntR family DIR45_13260 PF00107 Zinc-binding dehydrogenase DIR45_13260 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_13290 PF07486 Cell Wall Hydrolase DIR45_13305 PF00072 Response regulator receiver domain DIR45_13305 PF00486 Transcriptional regulatory protein, C terminal DIR45_13335 PF00005 ABC transporter DIR45_13360 PF00742 Homoserine dehydrogenase DIR45_13360 PF01842 ACT domain DIR45_13360 PF03447 Homoserine dehydrogenase, NAD binding domain DIR45_13365 PF00392 Bacterial regulatory proteins, gntR family DIR45_13365 PF00155 Aminotransferase class I and II DIR45_13370 PF07478 D-ala D-ala ligase C-terminus DIR45_13370 PF01820 D-ala D-ala ligase N-terminus DIR45_13375 PF03070 TENA/THI-4/PQQC family DIR45_13470 PF00067 Cytochrome P450 DIR45_13480 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_13485 PF07561 Domain of Unknown Function (DUF1540) DIR45_13495 PF00067 Cytochrome P450 DIR45_13515 PF13426 PAS domain DIR45_13515 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_13515 PF00989 PAS fold DIR45_13515 PF13188 PAS domain DIR45_13515 PF00512 His Kinase A (phospho-acceptor) domain DIR45_13525 PF00201 UDP-glucoronosyl and UDP-glucosyl transferase DIR45_13530 PF01177 Asp/Glu/Hydantoin racemase DIR45_13535 PF07155 ECF-type riboflavin transporter, S component DIR45_13540 PF00005 ABC transporter DIR45_13540 PF12558 ATP-binding cassette cobalt transporter DIR45_13555 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_13555 PF00512 His Kinase A (phospho-acceptor) domain DIR45_13570 PF00107 Zinc-binding dehydrogenase DIR45_13570 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_13585 PF11954 Domain of unknown function (DUF3471) DIR45_13585 PF00144 Beta-lactamase DIR45_13620 PF01965 DJ-1/PfpI family DIR45_13640 PF00144 Beta-lactamase DIR45_13655 PF07690 Major Facilitator Superfamily DIR45_13675 PF03009 Glycerophosphoryl diester phosphodiesterase family DIR45_13700 PF01270 Glycosyl hydrolases family 8 DIR45_13715 PF00293 NUDIX domain DIR45_13715 PF13344 Haloacid dehalogenase-like hydrolase DIR45_13735 PF07690 Major Facilitator Superfamily DIR45_13750 PF09297 NADH pyrophosphatase zinc ribbon domain DIR45_13750 PF00293 NUDIX domain DIR45_13755 PF00712 DNA polymerase III beta subunit, N-terminal domain DIR45_13755 PF02767 DNA polymerase III beta subunit, central domain DIR45_13755 PF02768 DNA polymerase III beta subunit, C-terminal domain DIR45_13760 PF00293 NUDIX domain DIR45_13775 PF12706 Beta-lactamase superfamily domain DIR45_13795 PF09234 Domain of unknown function (DUF1963) DIR45_13830 PF08000 Bacterial PH domain DIR45_13840 PF12867 DinB superfamily DIR45_13865 PF01541 GIY-YIG catalytic domain DIR45_13910 PF01266 FAD dependent oxidoreductase DIR45_13935 PF13419 Haloacid dehalogenase-like hydrolase DIR45_13950 PF07859 alpha/beta hydrolase fold DIR45_13955 PF00282 Pyridoxal-dependent decarboxylase conserved domain DIR45_13960 PF13193 AMP-binding enzyme C-terminal domain DIR45_13960 PF00501 AMP-binding enzyme DIR45_13960 PF00668 Condensation domain DIR45_13960 PF00550 Phosphopantetheine attachment site DIR45_13970 PF00128 Alpha amylase, catalytic domain DIR45_13970 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DIR45_13970 PF03714 Bacterial pullanase-associated domain DIR45_13975 PF07504 Fungalysin/Thermolysin Propeptide Motif DIR45_13975 PF01447 Thermolysin metallopeptidase, catalytic domain DIR45_13975 PF03413 Peptidase propeptide and YPEB domain DIR45_13975 PF02868 Thermolysin metallopeptidase, alpha-helical domain DIR45_13995 PF00344 SecY translocase DIR45_14000 PF00308 Bacterial dnaA protein DIR45_14000 PF08299 Bacterial dnaA protein helix-turn-helix DIR45_14000 PF11638 DnaA N-terminal domain DIR45_14005 PF00892 EamA-like transporter family DIR45_14010 PF00155 Aminotransferase class I and II DIR45_14010 PF00392 Bacterial regulatory proteins, gntR family DIR45_14015 PF00561 alpha/beta hydrolase fold DIR45_14040 PF06081 Aromatic acid exporter family member 1 DIR45_14055 PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DIR45_14060 PF03413 Peptidase propeptide and YPEB domain DIR45_14060 PF14620 YpeB sporulation DIR45_14065 PF07486 Cell Wall Hydrolase DIR45_14065 PF01471 Putative peptidoglycan binding domain DIR45_14080 PF03301 Tryptophan 2,3-dioxygenase DIR45_14085 PF04199 Putative cyclase DIR45_14090 PF00266 Aminotransferase class-V DIR45_14095 PF00440 Bacterial regulatory proteins, tetR family DIR45_14095 PF08359 YsiA-like protein, C-terminal region DIR45_14100 PF13344 Haloacid dehalogenase-like hydrolase DIR45_14100 PF00293 NUDIX domain DIR45_14130 PF01590 GAF domain DIR45_14130 PF02954 Bacterial regulatory protein, Fis family DIR45_14130 PF00158 Sigma-54 interaction domain DIR45_14145 PF13302 Acetyltransferase (GNAT) domain DIR45_14150 PF08220 DeoR-like helix-turn-helix domain DIR45_14150 PF00455 DeoR C terminal sensor domain DIR45_14165 PF00403 Heavy-metal-associated domain DIR45_14165 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_14165 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_14170 PF02082 Transcriptional regulator DIR45_14190 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_14190 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_14195 PF00364 Biotin-requiring enzyme DIR45_14195 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DIR45_14195 PF02817 e3 binding domain DIR45_14200 PF02779 Transketolase, pyrimidine binding domain DIR45_14200 PF02780 Transketolase, C-terminal domain DIR45_14205 PF00676 Dehydrogenase E1 component DIR45_14215 PF00106 short chain dehydrogenase DIR45_14220 PF13673 Acetyltransferase (GNAT) domain DIR45_14220 PF04229 GrpB protein DIR45_14255 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_14260 PF00571 CBS domain DIR45_14260 PF00005 ABC transporter DIR45_14265 PF04069 Substrate binding domain of ABC-type glycine betaine transport system DIR45_14270 PF00574 Clp protease DIR45_14285 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DIR45_14290 PF13673 Acetyltransferase (GNAT) domain DIR45_14295 PF18416 N-acetylglucosamine binding protein domain 2 DIR45_14295 PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading DIR45_14310 PF10990 Protein of unknown function (DUF2809) DIR45_14340 PF13567 Domain of unknown function (DUF4131) DIR45_14340 PF00753 Metallo-beta-lactamase superfamily DIR45_14340 PF03772 Competence protein DIR45_14390 PF13538 UvrD-like helicase C-terminal domain DIR45_14405 PF06094 Gamma-glutamyl cyclotransferase, AIG2-like DIR45_14410 PF16124 RecQ zinc-binding DIR45_14410 PF00270 DEAD/DEAH box helicase DIR45_14410 PF00570 HRDC domain DIR45_14410 PF09382 RQC domain DIR45_14410 PF00271 Helicase conserved C-terminal domain DIR45_14460 PF02833 DHHA2 domain DIR45_14460 PF01368 DHH family DIR45_14465 PF18416 N-acetylglucosamine binding protein domain 2 DIR45_14465 PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading DIR45_14480 PF02627 Carboxymuconolactone decarboxylase family DIR45_14485 PF01235 Sodium:alanine symporter family DIR45_14490 PF00171 Aldehyde dehydrogenase family DIR45_14495 PF00701 Dihydrodipicolinate synthetase family DIR45_14500 PF05544 Proline racemase DIR45_14505 PF05544 Proline racemase DIR45_14510 PF01266 FAD dependent oxidoreductase DIR45_14515 PF02954 Bacterial regulatory protein, Fis family DIR45_14515 PF13188 PAS domain DIR45_14515 PF00158 Sigma-54 interaction domain DIR45_14530 PF04324 BFD-like [2Fe-2S] binding domain DIR45_14530 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_14545 PF08876 Domain of unknown function (DUF1836) DIR45_14550 PF09335 SNARE associated Golgi protein DIR45_14565 PF04914 DltD protein DIR45_14570 PF13302 Acetyltransferase (GNAT) domain DIR45_14570 PF13673 Acetyltransferase (GNAT) domain DIR45_14570 PF00117 Glutamine amidotransferase class-I DIR45_14570 PF03352 Methyladenine glycosylase DIR45_14570 PF00958 GMP synthase C terminal domain DIR45_14575 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_14580 PF00877 NlpC/P60 family DIR45_14580 PF18348 Bacterial dipeptidyl-peptidase Sh3 domain DIR45_14585 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DIR45_14585 PF13378 Enolase C-terminal domain-like DIR45_14605 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region DIR45_14635 PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DIR45_14635 PF02129 X-Pro dipeptidyl-peptidase (S15 family) DIR45_14640 PF16736 Single Cache-like DIR45_14640 PF00989 PAS fold DIR45_14640 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_14640 PF00512 His Kinase A (phospho-acceptor) domain DIR45_14645 PF00072 Response regulator receiver domain DIR45_14645 PF00486 Transcriptional regulatory protein, C terminal DIR45_14665 PF01048 Phosphorylase superfamily DIR45_14675 PF03808 Glycosyl transferase WecB/TagA/CpsF family DIR45_14680 PF08439 Oligopeptidase F DIR45_14680 PF01432 Peptidase family M3 DIR45_14695 PF02645 Uncharacterised protein, DegV family COG1307 DIR45_14720 PF07690 Major Facilitator Superfamily DIR45_14730 PF04519 Polymer-forming cytoskeletal DIR45_14735 PF13171 Protein of unknown function (DUF4004) DIR45_14740 PF12793 Sugar transport-related sRNA regulator N-term DIR45_14740 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_14745 PF07690 Major Facilitator Superfamily DIR45_14765 PF04226 Transglycosylase associated protein DIR45_14770 PF01156 Inosine-uridine preferring nucleoside hydrolase DIR45_14780 PF08241 Methyltransferase domain DIR45_14820 PF00155 Aminotransferase class I and II DIR45_14825 PF07977 FabA-like domain DIR45_14830 PF03630 Fumble DIR45_14850 PF00005 ABC transporter DIR45_14900 PF01594 AI-2E family transporter DIR45_14915 PF00296 Luciferase-like monooxygenase DIR45_14920 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_14925 PF09084 NMT1/THI5 like DIR45_14930 PF00005 ABC transporter DIR45_14970 PF02522 Aminoglycoside 3-N-acetyltransferase DIR45_15000 PF13536 Putative multidrug resistance efflux transporter DIR45_15005 PF12867 DinB superfamily DIR45_15025 PF08713 DNA alkylation repair enzyme DIR45_15040 PF01522 Polysaccharide deacetylase DIR45_15050 PF03741 Integral membrane protein TerC family DIR45_15055 PF00884 Sulfatase DIR45_15065 PF00005 ABC transporter DIR45_15065 PF12848 ABC transporter DIR45_15080 PF16295 Tetracyclin repressor-like, C-terminal domain DIR45_15080 PF00440 Bacterial regulatory proteins, tetR family DIR45_15090 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DIR45_15095 PF02153 Prephenate dehydrogenase DIR45_15095 PF01842 ACT domain DIR45_15100 PF00155 Aminotransferase class I and II DIR45_15105 PF01264 Chorismate synthase DIR45_15115 PF00793 DAHP synthetase I family DIR45_15115 PF01817 Chorismate mutase type II DIR45_15140 PF01636 Phosphotransferase enzyme family DIR45_15155 PF06725 3D domain DIR45_15155 PF01476 LysM domain DIR45_15170 PF08281 Sigma-70, region 4 DIR45_15170 PF04542 Sigma-70 region 2 DIR45_15190 PF06039 Malate:quinone oxidoreductase (Mqo) DIR45_15195 PF13407 Periplasmic binding protein domain DIR45_15200 PF02653 Branched-chain amino acid transport system / permease component DIR45_15205 PF02653 Branched-chain amino acid transport system / permease component DIR45_15210 PF00005 ABC transporter DIR45_15215 PF00325 Bacterial regulatory proteins, crp family DIR45_15215 PF04198 Putative sugar-binding domain DIR45_15220 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_15220 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_15230 PF01791 DeoC/LacD family aldolase DIR45_15250 PF03992 Antibiotic biosynthesis monooxygenase DIR45_15270 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_15270 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_15275 PF00171 Aldehyde dehydrogenase family DIR45_15280 PF01472 PUA domain DIR45_15280 PF00696 Amino acid kinase family DIR45_15290 PF03807 NADP oxidoreductase coenzyme F420-dependent DIR45_15290 PF14748 Pyrroline-5-carboxylate reductase dimerisation DIR45_15295 PF01546 Peptidase family M20/M25/M40 DIR45_15300 PF09339 IclR helix-turn-helix domain DIR45_15300 PF01614 Bacterial transcriptional regulator DIR45_15310 PF00324 Amino acid permease DIR45_15315 PF01139 tRNA-splicing ligase RtcB DIR45_15320 PF00487 Fatty acid desaturase DIR45_15325 PF00245 Alkaline phosphatase DIR45_15330 PF11188 Protein of unknown function (DUF2975) DIR45_15335 PF13443 Cro/C1-type HTH DNA-binding domain DIR45_15350 PF10086 YhfC intramembrane metalloprotease DIR45_15360 PF00072 Response regulator receiver domain DIR45_15360 PF04397 LytTr DNA-binding domain DIR45_15370 PF13302 Acetyltransferase (GNAT) domain DIR45_15375 PF12681 Glyoxalase-like domain DIR45_15395 PF07726 ATPase family associated with various cellular activities (AAA) DIR45_15395 PF17863 AAA lid domain DIR45_15410 PF07690 Major Facilitator Superfamily DIR45_15420 PF00535 Glycosyl transferase family 2 DIR45_15435 PF00535 Glycosyl transferase family 2 DIR45_15445 PF00535 Glycosyl transferase family 2 DIR45_15455 PF00202 Aminotransferase class-III DIR45_15460 PF00199 Catalase DIR45_15460 PF06628 Catalase-related immune-responsive DIR45_15470 PF01979 Amidohydrolase family DIR45_15470 PF13382 Adenine deaminase C-terminal domain DIR45_15475 PF00144 Beta-lactamase DIR45_15495 PF17863 AAA lid domain DIR45_15495 PF07726 ATPase family associated with various cellular activities (AAA) DIR45_15505 PF00881 Nitroreductase family DIR45_15510 PF01047 MarR family DIR45_15520 PF03764 Elongation factor G, domain IV DIR45_15520 PF00679 Elongation factor G C-terminus DIR45_15520 PF14492 Elongation Factor G, domain II DIR45_15520 PF00009 Elongation factor Tu GTP binding domain DIR45_15530 PF00293 NUDIX domain DIR45_15545 PF00005 ABC transporter DIR45_15550 PF00392 Bacterial regulatory proteins, gntR family DIR45_15565 PF00005 ABC transporter DIR45_15565 PF12704 MacB-like periplasmic core domain DIR45_15565 PF02687 FtsX-like permease family DIR45_15590 PF12833 Helix-turn-helix domain DIR45_15595 PF00583 Acetyltransferase (GNAT) family DIR45_15610 PF00892 EamA-like transporter family DIR45_15615 PF00392 Bacterial regulatory proteins, gntR family DIR45_15615 PF00155 Aminotransferase class I and II DIR45_15620 PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 DIR45_15625 PF13031 Protein of unknown function (DUF3892) DIR45_15635 PF00672 HAMP domain DIR45_15635 PF00512 His Kinase A (phospho-acceptor) domain DIR45_15640 PF00072 Response regulator receiver domain DIR45_15640 PF00486 Transcriptional regulatory protein, C terminal DIR45_15645 PF00561 alpha/beta hydrolase fold DIR45_15675 PF01925 Sulfite exporter TauE/SafE DIR45_15680 PF13302 Acetyltransferase (GNAT) domain DIR45_15685 PF00324 Amino acid permease DIR45_15695 PF08713 DNA alkylation repair enzyme DIR45_15700 PF10898 Protein of unknown function (DUF2716) DIR45_15720 PF00293 NUDIX domain DIR45_15730 PF10502 Signal peptidase, peptidase S26 DIR45_15745 PF02146 Sir2 family DIR45_15770 PF03746 LamB/YcsF family DIR45_15780 PF02682 Carboxyltransferase domain, subdomain C and D DIR45_15785 PF09339 IclR helix-turn-helix domain DIR45_15785 PF01614 Bacterial transcriptional regulator DIR45_15790 PF10502 Signal peptidase, peptidase S26 DIR45_15795 PF03932 CutC family DIR45_15800 PF07454 Stage II sporulation protein P (SpoIIP) DIR45_15815 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_15815 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_15815 PF08028 Acyl-CoA dehydrogenase, C-terminal domain DIR45_15850 PF02915 Rubrerythrin DIR45_15860 PF00440 Bacterial regulatory proteins, tetR family DIR45_15865 PF00391 PEP-utilising enzyme, mobile domain DIR45_15865 PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DIR45_15875 PF00753 Metallo-beta-lactamase superfamily DIR45_15890 PF07875 Coat F domain DIR45_15900 PF08892 YqcI/YcgG family DIR45_15905 PF01810 LysE type translocator DIR45_15920 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_15925 PF10710 Protein of unknown function (DUF2512) DIR45_15930 PF11553 Protein of unknown function (DUF3231) DIR45_15935 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_15940 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_15940 PF00107 Zinc-binding dehydrogenase DIR45_15940 PF13823 Alcohol dehydrogenase GroES-associated DIR45_15955 PF00206 Lyase DIR45_15955 PF10415 Fumarase C C-terminus DIR45_15960 PF00710 Asparaginase, N-terminal DIR45_15960 PF17763 Glutaminase/Asparaginase C-terminal domain DIR45_15965 PF01381 Helix-turn-helix DIR45_15975 PF02151 UvrB/uvrC motif DIR45_15975 PF08459 UvrC Helix-hairpin-helix N-terminal DIR45_15975 PF01541 GIY-YIG catalytic domain DIR45_15975 PF12826 Helix-hairpin-helix motif DIR45_15980 PF13520 Amino acid permease DIR45_15985 PF05525 Branched-chain amino acid transport protein DIR45_15990 PF14748 Pyrroline-5-carboxylate reductase dimerisation DIR45_15990 PF03807 NADP oxidoreductase coenzyme F420-dependent DIR45_15995 PF13564 DoxX-like family DIR45_16000 PF00390 Malic enzyme, N-terminal domain DIR45_16000 PF03949 Malic enzyme, NAD binding domain DIR45_16015 PF03845 Spore germination protein DIR45_16030 PF00072 Response regulator receiver domain DIR45_16030 PF08664 YcbB domain DIR45_16040 PF04960 Glutaminase DIR45_16045 PF01235 Sodium:alanine symporter family DIR45_16075 PF17936 Bacterial Ig domain DIR45_16075 PF02872 5'-nucleotidase, C-terminal domain DIR45_16075 PF00149 Calcineurin-like phosphoesterase DIR45_16080 PF00199 Catalase DIR45_16080 PF06628 Catalase-related immune-responsive DIR45_16085 PF00561 alpha/beta hydrolase fold DIR45_16090 PF00857 Isochorismatase family DIR45_16105 PF01979 Amidohydrolase family DIR45_16110 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_16110 PF03466 LysR substrate binding domain DIR45_16120 PF01047 MarR family DIR45_16125 PF01544 CorA-like Mg2+ transporter protein DIR45_16140 PF11181 Heat induced stress protein YflT DIR45_16160 PF03073 TspO/MBR family DIR45_16165 PF00875 DNA photolyase DIR45_16165 PF03441 FAD binding domain of DNA photolyase DIR45_16175 PF10070 Uncharacterized protein conserved in bacteria (DUF2309) DIR45_16180 PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DIR45_16180 PF00361 Proton-conducting membrane transporter DIR45_16185 PF10057 Uncharacterized conserved protein (DUF2294) DIR45_16200 PF01040 UbiA prenyltransferase family DIR45_16205 PF00561 alpha/beta hydrolase fold DIR45_16215 PF01297 Zinc-uptake complex component A periplasmic DIR45_16220 PF00950 ABC 3 transport family DIR45_16225 PF00005 ABC transporter DIR45_16250 PF01451 Low molecular weight phosphotyrosine protein phosphatase DIR45_16255 PF01758 Sodium Bile acid symporter family DIR45_16260 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_16265 PF01022 Bacterial regulatory protein, arsR family DIR45_16280 PF00012 Hsp70 protein DIR45_16300 PF01037 Lrp/AsnC ligand binding domain DIR45_16320 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_16330 PF01609 Transposase DDE domain DIR45_16340 PF12833 Helix-turn-helix domain DIR45_16340 PF02805 Metal binding domain of Ada DIR45_16350 PF00144 Beta-lactamase DIR45_16375 PF12802 MarR family DIR45_16380 PF00067 Cytochrome P450 DIR45_16380 PF00258 Flavodoxin DIR45_16380 PF00667 FAD binding domain DIR45_16380 PF00175 Oxidoreductase NAD-binding domain DIR45_16390 PF07690 Major Facilitator Superfamily DIR45_16420 PF00072 Response regulator receiver domain DIR45_16420 PF00486 Transcriptional regulatory protein, C terminal DIR45_16425 PF00672 HAMP domain DIR45_16425 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_16425 PF00512 His Kinase A (phospho-acceptor) domain DIR45_16460 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_16490 PF01381 Helix-turn-helix DIR45_16505 PF00753 Metallo-beta-lactamase superfamily DIR45_16510 PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family DIR45_16520 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DIR45_16520 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DIR45_16525 PF04072 Leucine carboxyl methyltransferase DIR45_16540 PF00005 ABC transporter DIR45_16545 PF02687 FtsX-like permease family DIR45_16560 PF00512 His Kinase A (phospho-acceptor) domain DIR45_16560 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_16560 PF00672 HAMP domain DIR45_16565 PF00072 Response regulator receiver domain DIR45_16565 PF00486 Transcriptional regulatory protein, C terminal DIR45_16575 PF01047 MarR family DIR45_16585 PF04299 Putative FMN-binding domain DIR45_16590 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_16590 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_16595 PF07690 Major Facilitator Superfamily DIR45_16600 PF02589 LUD domain DIR45_16605 PF13183 4Fe-4S dicluster domain DIR45_16605 PF02589 LUD domain DIR45_16605 PF11870 Domain of unknown function (DUF3390) DIR45_16610 PF02754 Cysteine-rich domain DIR45_16615 PF03466 LysR substrate binding domain DIR45_16615 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_16625 PF17676 LD-carboxypeptidase C-terminal domain DIR45_16625 PF02016 LD-carboxypeptidase N-terminal domain DIR45_16660 PF02894 Oxidoreductase family, C-terminal alpha/beta domain DIR45_16660 PF01408 Oxidoreductase family, NAD-binding Rossmann fold DIR45_16665 PF05116 Sucrose-6F-phosphate phosphohydrolase DIR45_16675 PF00356 Bacterial regulatory proteins, lacI family DIR45_16680 PF18801 response regulator aspartate phosphatase H, N terminal DIR45_16700 PF00817 impB/mucB/samB family DIR45_16700 PF11799 impB/mucB/samB family C-terminal domain DIR45_16700 PF11798 IMS family HHH motif DIR45_16715 PF02743 Cache domain DIR45_16715 PF00672 HAMP domain DIR45_16715 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_16730 PF01554 MatE DIR45_16745 PF08453 Peptidase family M9 N-terminal DIR45_16745 PF01752 Collagenase DIR45_16745 PF18496 Collagenase G catalytic helper subdomain DIR45_16750 PF02661 Fic/DOC family DIR45_16755 PF07690 Major Facilitator Superfamily DIR45_16760 PF00440 Bacterial regulatory proteins, tetR family DIR45_16760 PF16859 Tetracyclin repressor-like, C-terminal domain DIR45_16770 PF01022 Bacterial regulatory protein, arsR family DIR45_16780 PF03313 Serine dehydratase alpha chain DIR45_16800 PF00202 Aminotransferase class-III DIR45_16805 PF00708 Acylphosphatase DIR45_16805 PF17788 HypF Kae1-like domain DIR45_16805 PF01300 Telomere recombination DIR45_16805 PF07503 HypF finger DIR45_16810 PF00586 AIR synthase related protein, N-terminal domain DIR45_16810 PF02769 AIR synthase related protein, C-terminal domain DIR45_16820 PF01037 Lrp/AsnC ligand binding domain DIR45_16825 PF13520 Amino acid permease DIR45_16845 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DIR45_16845 PF01842 ACT domain DIR45_16845 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DIR45_16850 PF00266 Aminotransferase class-V DIR45_16865 PF04542 Sigma-70 region 2 DIR45_16865 PF08281 Sigma-70, region 4 DIR45_16880 PF07883 Cupin domain DIR45_16890 PF01497 Periplasmic binding protein DIR45_16890 PF12833 Helix-turn-helix domain DIR45_16900 PF01804 Penicillin amidase DIR45_16940 PF14044 NETI protein DIR45_16945 PF07690 Major Facilitator Superfamily DIR45_16950 PF12697 Alpha/beta hydrolase family DIR45_16955 PF01047 MarR family DIR45_16960 PF07690 Major Facilitator Superfamily DIR45_16975 PF12679 ABC-2 family transporter protein DIR45_16980 PF00005 ABC transporter DIR45_16980 PF13732 Domain of unknown function (DUF4162) DIR45_16985 PF13396 Phospholipase_D-nuclease N-terminal DIR45_16995 PF17314 Family of unknown function (DUF5360) DIR45_17000 PF00893 Small Multidrug Resistance protein DIR45_17005 PF00440 Bacterial regulatory proteins, tetR family DIR45_17010 PF17440 Thiol-activated cytolysin beta sandwich domain DIR45_17010 PF01289 Thiol-activated cytolysin DIR45_17015 PF02667 Short chain fatty acid transporter DIR45_17025 PF02525 Flavodoxin-like fold DIR45_17055 PF00005 ABC transporter DIR45_17060 PF02361 Cobalt transport protein DIR45_17075 PF03737 Aldolase/RraA DIR45_17080 PF03606 C4-dicarboxylate anaerobic carrier DIR45_17085 PF04231 Endonuclease I DIR45_17100 PF01381 Helix-turn-helix DIR45_17105 PF02660 Glycerol-3-phosphate acyltransferase DIR45_17110 PF04073 Aminoacyl-tRNA editing domain DIR45_17115 PF03129 Anticodon binding domain DIR45_17115 PF13393 Histidyl-tRNA synthetase DIR45_17130 PF01638 HxlR-like helix-turn-helix DIR45_17135 PF00881 Nitroreductase family DIR45_17145 PF00224 Pyruvate kinase, barrel domain DIR45_17145 PF00391 PEP-utilising enzyme, mobile domain DIR45_17145 PF02887 Pyruvate kinase, alpha/beta domain DIR45_17170 PF00005 ABC transporter DIR45_17195 PF13419 Haloacid dehalogenase-like hydrolase DIR45_17230 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_17235 PF00480 ROK family DIR45_17240 PF07690 Major Facilitator Superfamily DIR45_17245 PF12464 Maltose acetyltransferase DIR45_17245 PF14602 Hexapeptide repeat of succinyl-transferase DIR45_17255 PF00005 ABC transporter DIR45_17265 PF00579 tRNA synthetases class I (W and Y) DIR45_17270 PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase DIR45_17270 PF13288 DXP reductoisomerase C-terminal domain DIR45_17270 PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DIR45_17275 PF01594 AI-2E family transporter DIR45_17295 PF08241 Methyltransferase domain DIR45_17305 PF07690 Major Facilitator Superfamily DIR45_17325 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_17335 PF00571 CBS domain DIR45_17335 PF01595 Cyclin M transmembrane N-terminal domain DIR45_17335 PF03471 Transporter associated domain DIR45_17340 PF13411 MerR HTH family regulatory protein DIR45_17345 PF00892 EamA-like transporter family DIR45_17350 PF00805 Pentapeptide repeats (8 copies) DIR45_17355 PF06906 Protein of unknown function (DUF1272) DIR45_17365 PF10282 Lactonase, 7-bladed beta-propeller DIR45_17370 PF02782 FGGY family of carbohydrate kinases, C-terminal domain DIR45_17370 PF00370 FGGY family of carbohydrate kinases, N-terminal domain DIR45_17375 PF02447 GntP family permease DIR45_17380 PF00923 Transaldolase/Fructose-6-phosphate aldolase DIR45_17385 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase DIR45_17385 PF00393 6-phosphogluconate dehydrogenase, C-terminal domain DIR45_17390 PF02780 Transketolase, C-terminal domain DIR45_17390 PF00456 Transketolase, thiamine diphosphate binding domain DIR45_17390 PF02779 Transketolase, pyrimidine binding domain DIR45_17395 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain DIR45_17395 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain DIR45_17400 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain DIR45_17400 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain DIR45_17405 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_17405 PF00107 Zinc-binding dehydrogenase DIR45_17410 PF00296 Luciferase-like monooxygenase DIR45_17420 PF08659 KR domain DIR45_17420 PF02801 Beta-ketoacyl synthase, C-terminal domain DIR45_17420 PF00109 Beta-ketoacyl synthase, N-terminal domain DIR45_17420 PF16197 Ketoacyl-synthetase C-terminal extension DIR45_17420 PF00107 Zinc-binding dehydrogenase DIR45_17420 PF00550 Phosphopantetheine attachment site DIR45_17420 PF14765 Polyketide synthase dehydratase DIR45_17420 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_17420 PF00698 Acyl transferase domain DIR45_17430 PF00106 short chain dehydrogenase DIR45_17435 PF03413 Peptidase propeptide and YPEB domain DIR45_17435 PF07504 Fungalysin/Thermolysin Propeptide Motif DIR45_17435 PF01447 Thermolysin metallopeptidase, catalytic domain DIR45_17435 PF02868 Thermolysin metallopeptidase, alpha-helical domain DIR45_17455 PF00248 Aldo/keto reductase family DIR45_17460 PF07690 Major Facilitator Superfamily DIR45_17475 PF03928 Haem-degrading DIR45_17480 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_17510 PF03960 ArsC family DIR45_17520 PF01638 HxlR-like helix-turn-helix DIR45_17525 PF07702 UTRA domain DIR45_17525 PF00392 Bacterial regulatory proteins, gntR family DIR45_17530 PF02894 Oxidoreductase family, C-terminal alpha/beta domain DIR45_17530 PF01408 Oxidoreductase family, NAD-binding Rossmann fold DIR45_17540 PF01638 HxlR-like helix-turn-helix DIR45_17545 PF01638 HxlR-like helix-turn-helix DIR45_17550 PF00248 Aldo/keto reductase family DIR45_17580 PF02567 Phenazine biosynthesis-like protein DIR45_17600 PF00501 AMP-binding enzyme DIR45_17600 PF13193 AMP-binding enzyme C-terminal domain DIR45_17610 PF01638 HxlR-like helix-turn-helix DIR45_17630 PF01022 Bacterial regulatory protein, arsR family DIR45_17640 PF12791 Anti-sigma factor N-terminus DIR45_17645 PF04542 Sigma-70 region 2 DIR45_17650 PF18674 TarS beta-glycosyltransferase C-terminal domain 1 DIR45_17650 PF00535 Glycosyl transferase family 2 DIR45_17660 PF00440 Bacterial regulatory proteins, tetR family DIR45_17680 PF05656 Protein of unknown function (DUF805) DIR45_17685 PF01061 ABC-2 type transporter DIR45_17690 PF00005 ABC transporter DIR45_17690 PF13732 Domain of unknown function (DUF4162) DIR45_17710 PF03063 Prismane/CO dehydrogenase family DIR45_17725 PF00753 Metallo-beta-lactamase superfamily DIR45_17730 PF01471 Putative peptidoglycan binding domain DIR45_17730 PF01183 Glycosyl hydrolases family 25 DIR45_17755 PF00144 Beta-lactamase DIR45_17795 PF00753 Metallo-beta-lactamase superfamily DIR45_17800 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_17800 PF00107 Zinc-binding dehydrogenase DIR45_17805 PF00324 Amino acid permease DIR45_17810 PF07690 Major Facilitator Superfamily DIR45_17840 PF02585 GlcNAc-PI de-N-acetylase DIR45_17845 PF08830 Protein of unknown function (DUF1806) DIR45_17850 PF03600 Citrate transporter DIR45_17880 PF01032 FecCD transport family DIR45_17885 PF01032 FecCD transport family DIR45_17890 PF05675 Protein of unknown function (DUF817) DIR45_17895 PF02567 Phenazine biosynthesis-like protein DIR45_17900 PF13170 Protein of unknown function (DUF4003) DIR45_17915 PF10901 Protein of unknown function (DUF2690) DIR45_17925 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_17925 PF03466 LysR substrate binding domain DIR45_17930 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_17930 PF00107 Zinc-binding dehydrogenase DIR45_17945 PF00488 MutS domain V DIR45_17945 PF01713 Smr domain DIR45_17960 PF00797 N-acetyltransferase DIR45_17965 PF01432 Peptidase family M3 DIR45_17965 PF08439 Oligopeptidase F DIR45_17970 PF00144 Beta-lactamase DIR45_17985 PF03466 LysR substrate binding domain DIR45_17985 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_18000 PF03009 Glycerophosphoryl diester phosphodiesterase family DIR45_18020 PF01494 FAD binding domain DIR45_18025 PF01022 Bacterial regulatory protein, arsR family DIR45_18030 PF00107 Zinc-binding dehydrogenase DIR45_18030 PF08240 Alcohol dehydrogenase GroES-like domain DIR45_18035 PF02696 Uncharacterized ACR, YdiU/UPF0061 family DIR45_18050 PF04299 Putative FMN-binding domain DIR45_18065 PF01758 Sodium Bile acid symporter family DIR45_18070 PF01565 FAD binding domain DIR45_18070 PF02913 FAD linked oxidases, C-terminal domain DIR45_18100 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_18105 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family DIR45_18110 PF00535 Glycosyl transferase family 2 DIR45_18115 PF00378 Enoyl-CoA hydratase/isomerase DIR45_18120 PF01752 Collagenase DIR45_18120 PF08453 Peptidase family M9 N-terminal DIR45_18120 PF18496 Collagenase G catalytic helper subdomain DIR45_18125 PF02308 MgtC family DIR45_18140 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_18145 PF04294 VanW like protein DIR45_18155 PF13039 Protein of unknown function (DUF3900) DIR45_18155 PF13037 Domain of unknown function (DUF3898) DIR45_18175 PF00313 'Cold-shock' DNA-binding domain DIR45_18185 PF00258 Flavodoxin DIR45_18195 PF00293 NUDIX domain DIR45_18205 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_18215 PF00106 short chain dehydrogenase DIR45_18235 PF01156 Inosine-uridine preferring nucleoside hydrolase DIR45_18240 PF00474 Sodium:solute symporter family DIR45_18250 PF00171 Aldehyde dehydrogenase family DIR45_18265 PF13249 Squalene-hopene cyclase N-terminal domain DIR45_18265 PF13243 Squalene-hopene cyclase C-terminal domain DIR45_18270 PF02681 Divergent PAP2 family DIR45_18275 PF00892 EamA-like transporter family DIR45_18280 PF06961 Protein of unknown function (DUF1294) DIR45_18295 PF10609 NUBPL iron-transfer P-loop NTPase DIR45_18305 PF02391 MoaE protein DIR45_18310 PF03453 MoeA N-terminal region (domain I and II) DIR45_18310 PF03454 MoeA C-terminal region (domain IV) DIR45_18310 PF00994 Probable molybdopterin binding domain DIR45_18315 PF00899 ThiF family DIR45_18320 PF01226 Formate/nitrite transporter DIR45_18330 PF04055 Radical SAM superfamily DIR45_18330 PF06463 Molybdenum Cofactor Synthesis C DIR45_18335 PF02634 FdhD/NarQ family DIR45_18340 PF10057 Uncharacterized conserved protein (DUF2294) DIR45_18345 PF07849 Protein of unknown function (DUF1641) DIR45_18350 PF00037 4Fe-4S binding domain DIR45_18350 PF04879 Molybdopterin oxidoreductase Fe4S4 domain DIR45_18350 PF00384 Molybdopterin oxidoreductase DIR45_18350 PF01568 Molydopterin dinucleotide binding domain DIR45_18350 PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DIR45_18360 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_18400 PF08241 Methyltransferase domain DIR45_18405 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_18410 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_18415 PF00375 Sodium:dicarboxylate symporter family DIR45_18420 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_18430 PF04542 Sigma-70 region 2 DIR45_18430 PF08281 Sigma-70, region 4 DIR45_18450 PF13732 Domain of unknown function (DUF4162) DIR45_18450 PF00005 ABC transporter DIR45_18460 PF02894 Oxidoreductase family, C-terminal alpha/beta domain DIR45_18460 PF01408 Oxidoreductase family, NAD-binding Rossmann fold DIR45_18465 PF00521 DNA gyrase/topoisomerase IV, subunit A DIR45_18465 PF03989 DNA gyrase C-terminal domain, beta-propeller DIR45_18470 PF00204 DNA gyrase B DIR45_18470 PF01751 Toprim domain DIR45_18470 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_18470 PF00986 DNA gyrase B subunit, carboxyl terminus DIR45_18480 PF13380 CoA binding domain DIR45_18485 PF13180 PDZ domain DIR45_18490 PF00486 Transcriptional regulatory protein, C terminal DIR45_18490 PF00072 Response regulator receiver domain DIR45_18500 PF13597 Anaerobic ribonucleoside-triphosphate reductase DIR45_18500 PF03477 ATP cone domain DIR45_18505 PF02660 Glycerol-3-phosphate acyltransferase DIR45_18510 PF01521 Iron-sulphur cluster biosynthesis DIR45_18515 PF03061 Thioesterase superfamily DIR45_18520 PF00704 Glycosyl hydrolases family 18 DIR45_18520 PF01476 LysM domain DIR45_18530 PF08177 Small acid-soluble spore protein N family DIR45_18535 PF13040 Fur-regulated basic protein B DIR45_18540 PF17657 Bacterial DNA polymerase III alpha subunit finger domain DIR45_18540 PF07733 Bacterial DNA polymerase III alpha NTPase domain DIR45_18540 PF01336 OB-fold nucleic acid binding domain DIR45_18540 PF00929 Exonuclease DIR45_18540 PF02811 PHP domain DIR45_18540 PF14579 Helix-hairpin-helix motif DIR45_18540 PF11490 DNA polymerase III polC-type N-terminus II DIR45_18550 PF00578 AhpC/TSA family DIR45_18560 PF00005 ABC transporter DIR45_18560 PF03412 Peptidase C39 family DIR45_18560 PF00664 ABC transporter transmembrane region DIR45_18565 PF00694 Aconitase C-terminal domain DIR45_18565 PF00330 Aconitase family (aconitate hydratase) DIR45_18575 PF01522 Polysaccharide deacetylase DIR45_18605 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain DIR45_18605 PF01411 tRNA synthetases class II (A) DIR45_18605 PF02272 DHHA1 domain DIR45_18610 PF13344 Haloacid dehalogenase-like hydrolase DIR45_18610 PF00293 NUDIX domain DIR45_18620 PF02803 Thiolase, C-terminal domain DIR45_18620 PF00108 Thiolase, N-terminal domain DIR45_18625 PF00501 AMP-binding enzyme DIR45_18625 PF13193 AMP-binding enzyme C-terminal domain DIR45_18630 PF02632 BioY family DIR45_18635 PF00501 AMP-binding enzyme DIR45_18635 PF13193 AMP-binding enzyme C-terminal domain DIR45_18660 PF05532 CsbD-like DIR45_18690 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_18690 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_18705 PF00989 PAS fold DIR45_18705 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_18705 PF13426 PAS domain DIR45_18705 PF00512 His Kinase A (phospho-acceptor) domain DIR45_18705 PF13188 PAS domain DIR45_18710 PF01738 Dienelactone hydrolase family DIR45_18715 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_18720 PF00474 Sodium:solute symporter family DIR45_18725 PF01645 Conserved region in glutamate synthase DIR45_18730 PF00724 NADH:flavin oxidoreductase / NADH oxidase family DIR45_18735 PF02559 CarD-like/TRCF domain DIR45_18740 PF00491 Arginase family DIR45_18745 PF01979 Amidohydrolase family DIR45_18750 PF17391 Urocanase N-terminal domain DIR45_18750 PF01175 Urocanase Rossmann-like domain DIR45_18750 PF17392 Urocanase C-terminal domain DIR45_18755 PF00221 Aromatic amino acid lyase DIR45_18760 PF09021 HutP DIR45_18765 PF01209 ubiE/COQ5 methyltransferase family DIR45_18790 PF11084 Protein of unknown function (DUF2621) DIR45_18825 PF07301 Protein of unknown function (DUF1453) DIR45_18830 PF02683 Cytochrome C biogenesis protein transmembrane region DIR45_18845 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_18845 PF03466 LysR substrate binding domain DIR45_18850 PF03788 LrgA family DIR45_18855 PF04172 LrgB-like family DIR45_18880 PF01471 Putative peptidoglycan binding domain DIR45_18880 PF01510 N-acetylmuramoyl-L-alanine amidase DIR45_18895 PF00664 ABC transporter transmembrane region DIR45_18895 PF00005 ABC transporter DIR45_18900 PF00664 ABC transporter transmembrane region DIR45_18900 PF00005 ABC transporter DIR45_18905 PF03672 Uncharacterised protein family (UPF0154) DIR45_18910 PF10747 Sporulation inhibitor of replication protein SirA DIR45_18915 PF02780 Transketolase, C-terminal domain DIR45_18915 PF00456 Transketolase, thiamine diphosphate binding domain DIR45_18915 PF02779 Transketolase, pyrimidine binding domain DIR45_18925 PF07282 Putative transposase DNA-binding domain DIR45_18925 PF12323 Helix-turn-helix domain DIR45_18925 PF01385 Probable transposase DIR45_18935 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_18940 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_18945 PF00005 ABC transporter DIR45_18960 PF05979 Bacterial protein of unknown function (DUF896) DIR45_18965 PF00239 Resolvase, N terminal domain DIR45_18970 PF00717 Peptidase S24-like DIR45_18970 PF01726 LexA DNA binding domain DIR45_18985 PF03551 Transcriptional regulator PadR-like family DIR45_19030 PF01510 N-acetylmuramoyl-L-alanine amidase DIR45_19030 PF01476 LysM domain DIR45_19030 PF01471 Putative peptidoglycan binding domain DIR45_19035 PF05105 Bacteriophage holin family DIR45_19185 PF08281 Sigma-70, region 4 DIR45_19230 PF02511 Thymidylate synthase complementing protein DIR45_19240 PF00145 C-5 cytosine-specific DNA methylase DIR45_19320 PF01381 Helix-turn-helix DIR45_19340 PF02899 Phage integrase, N-terminal SAM-like domain DIR45_19340 PF00589 Phage integrase family DIR45_19345 PF03951 Glutamine synthetase, beta-Grasp domain DIR45_19345 PF00120 Glutamine synthetase, catalytic domain DIR45_19350 PF13411 MerR HTH family regulatory protein DIR45_19355 PF06838 Methionine gamma-lyase DIR45_19360 PF01926 50S ribosome-binding GTPase DIR45_19360 PF13167 GTP-binding GTPase N-terminal DIR45_19360 PF16360 GTP-binding GTPase Middle Region DIR45_19365 PF03458 UPF0126 domain DIR45_19370 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_19370 PF17866 AAA lid domain DIR45_19385 PF17209 Hfq protein DIR45_19400 PF01476 LysM domain DIR45_19400 PF06725 3D domain DIR45_19410 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DIR45_19410 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit DIR45_19415 PF00294 pfkB family carbohydrate kinase DIR45_19420 PF00455 DeoR C terminal sensor domain DIR45_19420 PF08220 DeoR-like helix-turn-helix domain DIR45_19430 PF04238 Protein of unknown function (DUF420) DIR45_19445 PF00324 Amino acid permease DIR45_19455 PF00041 Fibronectin type III domain DIR45_19455 PF00704 Glycosyl hydrolases family 18 DIR45_19465 PF00149 Calcineurin-like phosphoesterase DIR45_19465 PF10518 TAT (twin-arginine translocation) pathway signal sequence DIR45_19470 PF01226 Formate/nitrite transporter DIR45_19475 PF00216 Bacterial DNA-binding protein DIR45_19485 PF00403 Heavy-metal-associated domain DIR45_19490 PF00403 Heavy-metal-associated domain DIR45_19495 PF02583 Metal-sensitive transcriptional repressor DIR45_19505 PF00756 Putative esterase DIR45_19510 PF00005 ABC transporter DIR45_19515 PF01032 FecCD transport family DIR45_19520 PF01032 FecCD transport family DIR45_19535 PF12833 Helix-turn-helix domain DIR45_19535 PF02805 Metal binding domain of Ada DIR45_19540 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain DIR45_19540 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DIR45_19545 PF07934 8-oxoguanine DNA glycosylase, N-terminal domain DIR45_19545 PF00730 HhH-GPD superfamily base excision DNA repair protein DIR45_19550 PF01546 Peptidase family M20/M25/M40 DIR45_19550 PF07687 Peptidase dimerisation domain DIR45_19575 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_19580 PF00563 EAL domain DIR45_19580 PF00990 Diguanylate cyclase, GGDEF domain DIR45_19580 PF03707 Bacterial signalling protein N terminal repeat DIR45_19595 PF10787 Uncharacterised protein from bacillus cereus group DIR45_19600 PF04172 LrgB-like family DIR45_19605 PF03788 LrgA family DIR45_19610 PF00155 Aminotransferase class I and II DIR45_19610 PF00392 Bacterial regulatory proteins, gntR family DIR45_19615 PF00364 Biotin-requiring enzyme DIR45_19615 PF00561 alpha/beta hydrolase fold DIR45_19620 PF02585 GlcNAc-PI de-N-acetylase DIR45_19635 PF00388 Phosphatidylinositol-specific phospholipase C, X domain DIR45_19640 PF00082 Subtilase family DIR45_19645 PF07486 Cell Wall Hydrolase DIR45_19650 PF03275 UDP-galactopyranose mutase DIR45_19655 PF00884 Sulfatase DIR45_19660 PF00350 Dynamin family DIR45_19670 PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family DIR45_19675 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_19675 PF00512 His Kinase A (phospho-acceptor) domain DIR45_19680 PF00486 Transcriptional regulatory protein, C terminal DIR45_19680 PF00072 Response regulator receiver domain DIR45_19695 PF00005 ABC transporter DIR45_19700 PF01119 DNA mismatch repair protein, C-terminal domain DIR45_19700 PF08676 MutL C terminal dimerisation domain DIR45_19705 PF01624 MutS domain I DIR45_19705 PF00488 MutS domain V DIR45_19705 PF05190 MutS family domain IV DIR45_19705 PF05188 MutS domain II DIR45_19705 PF05192 MutS domain III DIR45_19710 PF10628 Outer spore coat protein E (CotE) DIR45_19715 PF06133 Control of competence regulator ComK, YlbF/YmcA DIR45_19720 PF01938 TRAM domain DIR45_19720 PF00919 Uncharacterized protein family UPF0004 DIR45_19720 PF04055 Radical SAM superfamily DIR45_19725 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_19730 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II DIR45_19730 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DIR45_19730 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase DIR45_19735 PF01244 Membrane dipeptidase (Peptidase family M19) DIR45_19740 PF04232 Stage V sporulation protein S (SpoVS) DIR45_19745 PF13277 YmdB-like protein DIR45_19750 PF01966 HD domain DIR45_19750 PF12072 Domain of unknown function (DUF3552) DIR45_19750 PF00013 KH domain DIR45_19755 PF00154 recA bacterial DNA recombination protein DIR45_19765 PF00994 Probable molybdopterin binding domain DIR45_19765 PF18146 Damage-inducible protein CinA KH domain DIR45_19765 PF02464 Competence-damaged protein DIR45_19770 PF01066 CDP-alcohol phosphatidyltransferase DIR45_19775 PF13464 Domain of unknown function (DUF4115) DIR45_19780 PF11868 Protein of unknown function (DUF3388) DIR45_19785 PF11588 Protein of unknown function (DUF3243) DIR45_19795 PF00675 Insulinase (Peptidase family M16) DIR45_19795 PF05193 Peptidase M16 inactive domain DIR45_19800 PF05193 Peptidase M16 inactive domain DIR45_19825 PF00392 Bacterial regulatory proteins, gntR family DIR45_19825 PF07702 UTRA domain DIR45_19830 PF17854 FtsK alpha domain DIR45_19830 PF01580 FtsK/SpoIIIE family DIR45_19830 PF09397 Ftsk gamma domain DIR45_19835 PF14035 YlzJ-like protein DIR45_19840 PF00574 Clp protease DIR45_19845 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain DIR45_19845 PF17770 Ribonuclease J C-terminal domain DIR45_19845 PF00753 Metallo-beta-lactamase superfamily DIR45_19855 PF00701 Dihydrodipicolinate synthetase family DIR45_19860 PF00696 Amino acid kinase family DIR45_19860 PF13840 ACT domain DIR45_19865 PF02774 Semialdehyde dehydrogenase, dimerisation domain DIR45_19865 PF01118 Semialdehyde dehydrogenase, NAD binding domain DIR45_19870 PF02441 Flavoprotein DIR45_19875 PF01262 Alanine dehydrogenase/PNT, C-terminal domain DIR45_19875 PF16924 Dipicolinate synthase subunit A N-terminal domain DIR45_19885 PF05239 PRC-barrel domain DIR45_19890 PF05193 Peptidase M16 inactive domain DIR45_19890 PF00675 Insulinase (Peptidase family M16) DIR45_19895 PF01522 Polysaccharide deacetylase DIR45_19900 PF00013 KH domain DIR45_19900 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain DIR45_19900 PF01138 3' exoribonuclease family, domain 1 DIR45_19900 PF03725 3' exoribonuclease family, domain 2 DIR45_19900 PF00575 S1 RNA binding domain DIR45_19905 PF00312 Ribosomal protein S15 DIR45_19910 PF01687 Riboflavin kinase DIR45_19910 PF06574 FAD synthetase DIR45_19915 PF01509 TruB family pseudouridylate synthase (N terminal domain) DIR45_19915 PF16198 tRNA pseudouridylate synthase B C-terminal domain DIR45_19920 PF02033 Ribosome-binding factor A DIR45_19925 PF04456 Protein of unknown function (DUF503) DIR45_19930 PF00009 Elongation factor Tu GTP binding domain DIR45_19930 PF04760 Translation initiation factor IF-2, N-terminal region DIR45_19930 PF11987 Translation-initiation factor 2 DIR45_19935 PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DIR45_19940 PF04296 Protein of unknown function (DUF448) DIR45_19945 PF00575 S1 RNA binding domain DIR45_19945 PF08529 NusA N-terminal domain DIR45_19945 PF13184 NusA-like KH domain DIR45_19950 PF02576 RimP N-terminal domain DIR45_19950 PF17384 RimP C-terminal SH3 domain DIR45_19955 PF00929 Exonuclease DIR45_19955 PF02811 PHP domain DIR45_19955 PF14579 Helix-hairpin-helix motif DIR45_19955 PF17657 Bacterial DNA polymerase III alpha subunit finger domain DIR45_19955 PF07733 Bacterial DNA polymerase III alpha NTPase domain DIR45_19955 PF11490 DNA polymerase III polC-type N-terminus II DIR45_19955 PF14480 DNA polymerase III polC-type N-terminus I DIR45_19965 PF04073 Aminoacyl-tRNA editing domain DIR45_19965 PF03129 Anticodon binding domain DIR45_19965 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_19970 PF17820 PDZ domain DIR45_19970 PF02163 Peptidase family M50 DIR45_19975 PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DIR45_19975 PF13288 DXP reductoisomerase C-terminal domain DIR45_19975 PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase DIR45_19985 PF01255 Putative undecaprenyl diphosphate synthase DIR45_19990 PF01765 Ribosome recycling factor DIR45_19995 PF00696 Amino acid kinase family DIR45_20000 PF00889 Elongation factor TS DIR45_20005 PF00318 Ribosomal protein S2 DIR45_20010 PF08222 CodY helix-turn-helix domain DIR45_20010 PF06018 CodY GAF-like domain DIR45_20015 PF07724 AAA domain (Cdc48 subfamily) DIR45_20015 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_20015 PF10431 C-terminal, D2-small domain, of ClpB protein DIR45_20020 PF00227 Proteasome subunit DIR45_20025 PF00589 Phage integrase family DIR45_20025 PF02899 Phage integrase, N-terminal SAM-like domain DIR45_20030 PF01134 Glucose inhibited division protein A DIR45_20035 PF01131 DNA topoisomerase DIR45_20035 PF01751 Toprim domain DIR45_20035 PF01396 Topoisomerase DNA binding C4 zinc finger DIR45_20045 PF02629 CoA binding domain DIR45_20045 PF00549 CoA-ligase DIR45_20050 PF00549 CoA-ligase DIR45_20050 PF08442 ATP-grasp domain DIR45_20055 PF01351 Ribonuclease HII DIR45_20060 PF01926 50S ribosome-binding GTPase DIR45_20065 PF10502 Signal peptidase, peptidase S26 DIR45_20070 PF01245 Ribosomal protein L19 DIR45_20075 PF01746 tRNA (Guanine-1)-methyltransferase DIR45_20080 PF05239 PRC-barrel domain DIR45_20080 PF01782 RimM N-terminal domain DIR45_20090 PF00886 Ribosomal protein S16 DIR45_20095 PF02881 SRP54-type protein, helical bundle domain DIR45_20095 PF02978 Signal peptide binding domain DIR45_20095 PF00448 SRP54-type protein, GTPase domain DIR45_20100 PF04297 Putative helix-turn-helix protein, YlxM / p13 like DIR45_20105 PF02881 SRP54-type protein, helical bundle domain DIR45_20105 PF00448 SRP54-type protein, GTPase domain DIR45_20110 PF06470 SMC proteins Flexible Hinge Domain DIR45_20110 PF02463 RecF/RecN/SMC N terminal domain DIR45_20115 PF14622 Ribonuclease-III-like DIR45_20115 PF00035 Double-stranded RNA binding motif DIR45_20120 PF00550 Phosphopantetheine attachment site DIR45_20130 PF00698 Acyl transferase domain DIR45_20135 PF02504 Fatty acid synthesis protein DIR45_20140 PF03061 Thioesterase superfamily DIR45_20145 PF00270 DEAD/DEAH box helicase DIR45_20145 PF17191 RecG wedge domain DIR45_20145 PF00271 Helicase conserved C-terminal domain DIR45_20150 PF13684 Dihydroxyacetone kinase family DIR45_20150 PF02734 DAK2 domain DIR45_20155 PF03780 Asp23 family, cell envelope-related function DIR45_20160 PF00830 Ribosomal L28 family DIR45_20165 PF08183 Stage V sporulation protein family DIR45_20170 PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain DIR45_20170 PF04263 Thiamin pyrophosphokinase, catalytic domain DIR45_20175 PF00834 Ribulose-phosphate 3 epimerase family DIR45_20180 PF03193 RsgA GTPase DIR45_20180 PF16745 RsgA N-terminal domain DIR45_20185 PF00069 Protein kinase domain DIR45_20185 PF03793 PASTA domain DIR45_20195 PF04055 Radical SAM superfamily DIR45_20200 PF01029 NusB family DIR45_20200 PF01189 16S rRNA methyltransferase RsmB/F DIR45_20205 PF00551 Formyl transferase DIR45_20205 PF02911 Formyl transferase, C-terminal domain DIR45_20210 PF01327 Polypeptide deformylase DIR45_20215 PF17764 3′ DNA-binding domain (3′BD) DIR45_20215 PF04851 Type III restriction enzyme, res subunit DIR45_20215 PF18319 PriA DNA helicase Cys-rich region (CRR) domain DIR45_20215 PF18074 Primosomal protein N C-terminal domain DIR45_20215 PF00271 Helicase conserved C-terminal domain DIR45_20220 PF04127 DNA / pantothenate metabolism flavoprotein DIR45_20220 PF02441 Flavoprotein DIR45_20225 PF01192 RNA polymerase Rpb6 DIR45_20230 PF00625 Guanylate kinase DIR45_20235 PF04025 Domain of unknown function (DUF370) DIR45_20240 PF03755 YicC-like family, N-terminal region DIR45_20240 PF08340 Domain of unknown function (DUF1732) DIR45_20245 PF00689 Cation transporting ATPase, C-terminus DIR45_20245 PF00690 Cation transporter/ATPase, N-terminus DIR45_20255 PF00557 Metallopeptidase family M24 DIR45_20255 PF01321 Creatinase/Prolidase N-terminal domain DIR45_20290 PF00156 Phosphoribosyl transferase domain DIR45_20295 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family DIR45_20300 PF01180 Dihydroorotate dehydrogenase DIR45_20305 PF00175 Oxidoreductase NAD-binding domain DIR45_20305 PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DIR45_20310 PF02142 MGS-like domain DIR45_20310 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DIR45_20310 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain DIR45_20315 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain DIR45_20315 PF00117 Glutamine amidotransferase class-I DIR45_20320 PF01979 Amidohydrolase family DIR45_20325 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DIR45_20325 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DIR45_20330 PF00860 Permease family DIR45_20335 PF00156 Phosphoribosyl transferase domain DIR45_20340 PF01479 S4 domain DIR45_20340 PF00849 RNA pseudouridylate synthase DIR45_20345 PF01252 Signal peptidase (SPase) II DIR45_20355 PF06827 Zinc finger found in FPG and IleRS DIR45_20355 PF00133 tRNA synthetases class I (I, L, M and V) DIR45_20355 PF08264 Anticodon-binding domain of tRNA DIR45_20360 PF05103 DivIVA protein DIR45_20365 PF17774 Putative RNA-binding domain in YlmH DIR45_20365 PF01479 S4 domain DIR45_20370 PF02325 YGGT family DIR45_20375 PF04472 Cell division protein SepF DIR45_20380 PF01168 Alanine racemase, N-terminal domain DIR45_20390 PF05239 PRC-barrel domain DIR45_20395 PF04545 Sigma-70, region 4 DIR45_20395 PF04539 Sigma-70 region 3 DIR45_20395 PF04542 Sigma-70 region 2 DIR45_20400 PF04542 Sigma-70 region 2 DIR45_20400 PF04545 Sigma-70, region 4 DIR45_20405 PF03419 Sporulation factor SpoIIGA DIR45_20410 PF00091 Tubulin/FtsZ family, GTPase domain DIR45_20410 PF12327 FtsZ family, C-terminal domain DIR45_20415 PF02491 SHS2 domain inserted in FTSA DIR45_20420 PF08478 POTRA domain, FtsQ-type DIR45_20420 PF03799 Cell division protein FtsQ DIR45_20425 PF01565 FAD binding domain DIR45_20425 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DIR45_20430 PF03033 Glycosyltransferase family 28 N-terminal domain DIR45_20430 PF04101 Glycosyltransferase family 28 C-terminal domain DIR45_20435 PF01098 Cell cycle protein DIR45_20440 PF08245 Mur ligase middle domain DIR45_20440 PF02875 Mur ligase family, glutamate ligase domain DIR45_20445 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DIR45_20445 PF00953 Glycosyl transferase family 4 DIR45_20450 PF01225 Mur ligase family, catalytic domain DIR45_20450 PF08245 Mur ligase middle domain DIR45_20450 PF02875 Mur ligase family, glutamate ligase domain DIR45_20455 PF03793 PASTA domain DIR45_20455 PF00905 Penicillin binding protein transpeptidase domain DIR45_20455 PF03717 Penicillin-binding Protein dimerisation domain DIR45_20465 PF04977 Septum formation initiator DIR45_20470 PF01795 MraW methylase family DIR45_20475 PF10079 Bacillithiol biosynthesis BshC DIR45_20480 PF08546 Ketopantoate reductase PanE/ApbA C terminal DIR45_20480 PF02558 Ketopantoate reductase PanE/ApbA DIR45_20485 PF00583 Acetyltransferase (GNAT) family DIR45_20495 PF01783 Ribosomal L32p protein family DIR45_20500 PF02620 Large ribosomal RNA subunit accumulation protein YceD DIR45_20545 PF12123 N-acetylmuramoyl-l-alanine amidase DIR45_20545 PF01510 N-acetylmuramoyl-L-alanine amidase DIR45_20550 PF05105 Bacteriophage holin family DIR45_20630 PF00574 Clp protease DIR45_20640 PF03354 Phage Terminase DIR45_20660 PF10137 Predicted nucleotide-binding protein containing TIR-like domain DIR45_20665 PF00589 Phage integrase family DIR45_20755 PF04542 Sigma-70 region 2 DIR45_20755 PF04539 Sigma-70 region 3 DIR45_20755 PF04545 Sigma-70, region 4 DIR45_20780 PF01695 IstB-like ATP binding protein DIR45_20780 PF07319 Primosomal protein DnaI N-terminus DIR45_20810 PF01381 Helix-turn-helix DIR45_20830 PF01381 Helix-turn-helix DIR45_20850 PF00589 Phage integrase family DIR45_20850 PF14659 Phage integrase, N-terminal SAM-like domain DIR45_20855 PF05636 HIGH Nucleotidyl Transferase DIR45_20860 PF13180 PDZ domain DIR45_20860 PF05362 Lon protease (S16) C-terminal proteolytic domain DIR45_20865 PF01734 Patatin-like phospholipase DIR45_20870 PF07670 Nucleoside recognition DIR45_20875 PF01467 Cytidylyltransferase-like DIR45_20890 PF09902 Uncharacterized protein conserved in bacteria (DUF2129) DIR45_20895 PF06133 Control of competence regulator ComK, YlbF/YmcA DIR45_20900 PF00300 Histidine phosphatase superfamily (branch 1) DIR45_20905 PF14003 YlbE-like protein DIR45_20910 PF14071 Putative coat protein DIR45_20915 PF14504 CAP-associated N-terminal DIR45_20915 PF00188 Cysteine-rich secretory protein family DIR45_20920 PF08868 YugN-like family DIR45_20925 PF00795 Carbon-nitrogen hydrolase DIR45_20930 PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DIR45_20935 PF03626 Prokaryotic Cytochrome C oxidase subunit IV DIR45_20940 PF00510 Cytochrome c oxidase subunit III DIR45_20945 PF00115 Cytochrome C and Quinol oxidase polypeptide I DIR45_20950 PF02790 Cytochrome C oxidase subunit II, transmembrane domain DIR45_20950 PF00116 Cytochrome C oxidase subunit II, periplasmic domain DIR45_20950 PF00034 Cytochrome c DIR45_20955 PF01040 UbiA prenyltransferase family DIR45_20960 PF02628 Cytochrome oxidase assembly protein DIR45_20965 PF02785 Biotin carboxylase C-terminal domain DIR45_20965 PF00364 Biotin-requiring enzyme DIR45_20965 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain DIR45_20965 PF00682 HMGL-like DIR45_20965 PF00289 Biotin carboxylase, N-terminal domain DIR45_20965 PF02436 Conserved carboxylase domain DIR45_20975 PF01098 Cell cycle protein DIR45_20980 PF07408 Protein of unknown function (DUF1507) DIR45_20990 PF13638 PIN domain DIR45_20990 PF02562 PhoH-like protein DIR45_21000 PF09963 Uncharacterized protein conserved in bacteria (DUF2197) DIR45_21010 PF14036 YlaH-like protein DIR45_21025 PF00459 Inositol monophosphatase family DIR45_21035 PF06335 Protein of unknown function (DUF1054) DIR45_21040 PF05256 Uncharacterised protein family (UPF0223) DIR45_21045 PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain DIR45_21045 PF01276 Orn/Lys/Arg decarboxylase, major domain DIR45_21085 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_21085 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_21090 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DIR45_21090 PF00364 Biotin-requiring enzyme DIR45_21090 PF02817 e3 binding domain DIR45_21095 PF02780 Transketolase, C-terminal domain DIR45_21095 PF02779 Transketolase, pyrimidine binding domain DIR45_21100 PF00676 Dehydrogenase E1 component DIR45_21110 PF01327 Polypeptide deformylase DIR45_21130 PF00753 Metallo-beta-lactamase superfamily DIR45_21130 PF17770 Ribonuclease J C-terminal domain DIR45_21130 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain DIR45_21135 PF02080 TrkA-C domain DIR45_21135 PF02254 TrkA-N domain DIR45_21145 PF01546 Peptidase family M20/M25/M40 DIR45_21145 PF07687 Peptidase dimerisation domain DIR45_21150 PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal DIR45_21150 PF14602 Hexapeptide repeat of succinyl-transferase DIR45_21150 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_21155 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_21155 PF03466 LysR substrate binding domain DIR45_21170 PF04308 Ribonuclease H-like DIR45_21180 PF08796 Protein of unknown function (DUF1797) DIR45_21195 PF10388 EAL-domain associated signalling protein domain DIR45_21195 PF00563 EAL domain DIR45_21205 PF10518 TAT (twin-arginine translocation) pathway signal sequence DIR45_21205 PF00149 Calcineurin-like phosphoesterase DIR45_21225 PF02541 Ppx/GppA phosphatase family DIR45_21230 PF14177 YkyB-like protein DIR45_21260 PF07690 Major Facilitator Superfamily DIR45_21270 PF08267 Cobalamin-independent synthase, N-terminal domain DIR45_21270 PF01717 Cobalamin-independent synthase, Catalytic domain DIR45_21280 PF14040 Deoxyribonuclease NucA/NucB DIR45_21295 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_21295 PF00512 His Kinase A (phospho-acceptor) domain DIR45_21305 PF00155 Aminotransferase class I and II DIR45_21310 PF00356 Bacterial regulatory proteins, lacI family DIR45_21310 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family DIR45_21315 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_21320 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_21325 PF13416 Bacterial extracellular solute-binding protein DIR45_21330 PF00128 Alpha amylase, catalytic domain DIR45_21330 PF02903 Alpha amylase, N-terminal ig-like domain DIR45_21330 PF16657 Maltogenic Amylase, C-terminal domain DIR45_21335 PF16657 Maltogenic Amylase, C-terminal domain DIR45_21335 PF00128 Alpha amylase, catalytic domain DIR45_21340 PF03459 TOBE domain DIR45_21340 PF17912 MalK OB fold domain DIR45_21340 PF00005 ABC transporter DIR45_21380 PF02803 Thiolase, C-terminal domain DIR45_21380 PF00108 Thiolase, N-terminal domain DIR45_21385 PF00293 NUDIX domain DIR45_21420 PF03551 Transcriptional regulator PadR-like family DIR45_21440 PF01636 Phosphotransferase enzyme family DIR45_21445 PF00795 Carbon-nitrogen hydrolase DIR45_21450 PF00155 Aminotransferase class I and II DIR45_21455 PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain DIR45_21455 PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain DIR45_21465 PF00596 Class II Aldolase and Adducin N-terminal domain DIR45_21470 PF03079 ARD/ARD' family DIR45_21495 PF00990 Diguanylate cyclase, GGDEF domain DIR45_21500 PF00881 Nitroreductase family DIR45_21515 PF02896 PEP-utilising enzyme, TIM barrel domain DIR45_21515 PF00391 PEP-utilising enzyme, mobile domain DIR45_21515 PF05524 PEP-utilising enzyme, N-terminal DIR45_21520 PF00381 PTS HPr component phosphorylation site DIR45_21525 PF02378 Phosphotransferase system, EIIC DIR45_21525 PF00367 phosphotransferase system, EIIB DIR45_21525 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DIR45_21530 PF03123 CAT RNA binding domain DIR45_21530 PF00874 PRD domain DIR45_21545 PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DIR45_21550 PF01979 Amidohydrolase family DIR45_21560 PF04079 Segregation and condensation complex subunit ScpB DIR45_21570 PF02616 Segregation and condensation protein ScpA DIR45_21580 PF03745 Domain of unknown function (DUF309) DIR45_21585 PF00583 Acetyltransferase (GNAT) family DIR45_21595 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIR45_21600 PF06207 Protein of unknown function (DUF1002) DIR45_21610 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_21615 PF14097 Stage V sporulation protein AE1 DIR45_21620 PF03862 SpoVAC/SpoVAEB sporulation membrane protein DIR45_21625 PF07451 Stage V sporulation protein AD (SpoVAD) DIR45_21630 PF03862 SpoVAC/SpoVAEB sporulation membrane protein DIR45_21635 PF13782 Stage V sporulation protein AB DIR45_21640 PF12164 Stage V sporulation protein AA DIR45_21650 PF00209 Sodium:neurotransmitter symporter family DIR45_21655 PF04542 Sigma-70 region 2 DIR45_21655 PF04539 Sigma-70 region 3 DIR45_21655 PF04545 Sigma-70, region 4 DIR45_21660 PF13581 Histidine kinase-like ATPase domain DIR45_21665 PF01740 STAS domain DIR45_21670 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_21670 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_21680 PF00392 Bacterial regulatory proteins, gntR family DIR45_21685 PF00005 ABC transporter DIR45_21705 PF01047 MarR family DIR45_21715 PF00860 Permease family DIR45_21720 PF01544 CorA-like Mg2+ transporter protein DIR45_21725 PF02885 Glycosyl transferase family, helical bundle domain DIR45_21725 PF00591 Glycosyl transferase family, a/b domain DIR45_21725 PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain DIR45_21730 PF01048 Phosphorylase superfamily DIR45_21735 PF01676 Metalloenzyme superfamily DIR45_21745 PF02899 Phage integrase, N-terminal SAM-like domain DIR45_21745 PF00589 Phage integrase family DIR45_21750 PF14004 Protein of unknown function (DUF4227) DIR45_21755 PF01475 Ferric uptake regulator family DIR45_21760 PF01944 Stage II sporulation protein M DIR45_21770 PF00293 NUDIX domain DIR45_21775 PF13072 Mother cell inhibitor of FtsZ DIR45_21780 PF00248 Aldo/keto reductase family DIR45_21785 PF00248 Aldo/keto reductase family DIR45_21790 PF13673 Acetyltransferase (GNAT) domain DIR45_21790 PF04229 GrpB protein DIR45_21800 PF00565 Staphylococcal nuclease homologue DIR45_21800 PF00149 Calcineurin-like phosphoesterase DIR45_21800 PF00746 LPXTG cell wall anchor motif DIR45_21800 PF02872 5'-nucleotidase, C-terminal domain DIR45_21810 PF12146 Serine aminopeptidase, S33 DIR45_21815 PF03553 Na+/H+ antiporter family DIR45_21815 PF13726 Na+-H+ antiporter family DIR45_21825 PF00583 Acetyltransferase (GNAT) family DIR45_21830 PF12146 Serine aminopeptidase, S33 DIR45_21835 PF10827 Protein of unknown function (DUF2552) DIR45_21845 PF01872 RibD C-terminal domain DIR45_21845 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region DIR45_21850 PF00677 Lumazine binding domain DIR45_21855 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase DIR45_21855 PF00925 GTP cyclohydrolase II DIR45_21860 PF00885 6,7-dimethyl-8-ribityllumazine synthase DIR45_21870 PF06968 Biotin and Thiamin Synthesis associated domain DIR45_21870 PF04055 Radical SAM superfamily DIR45_21875 PF13847 Methyltransferase domain DIR45_21880 PF12697 Alpha/beta hydrolase family DIR45_21880 PF08241 Methyltransferase domain DIR45_21885 PF00155 Aminotransferase class I and II DIR45_21895 PF00202 Aminotransferase class-III DIR45_21915 PF02872 5'-nucleotidase, C-terminal domain DIR45_21915 PF00149 Calcineurin-like phosphoesterase DIR45_21925 PF01037 Lrp/AsnC ligand binding domain DIR45_21925 PF13404 AsnC-type helix-turn-helix domain DIR45_21940 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DIR45_21940 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DIR45_21945 PF00202 Aminotransferase class-III DIR45_21950 PF00696 Amino acid kinase family DIR45_21955 PF01960 ArgJ family DIR45_21960 PF02774 Semialdehyde dehydrogenase, dimerisation domain DIR45_21960 PF01118 Semialdehyde dehydrogenase, NAD binding domain DIR45_21970 PF00106 short chain dehydrogenase DIR45_21975 PF00753 Metallo-beta-lactamase superfamily DIR45_21980 PF14748 Pyrroline-5-carboxylate reductase dimerisation DIR45_21980 PF03807 NADP oxidoreductase coenzyme F420-dependent DIR45_21985 PF03313 Serine dehydratase alpha chain DIR45_21990 PF01842 ACT domain DIR45_21990 PF03315 Serine dehydratase beta chain DIR45_22000 PF12706 Beta-lactamase superfamily domain DIR45_22000 PF00753 Metallo-beta-lactamase superfamily DIR45_22015 PF11798 IMS family HHH motif DIR45_22015 PF11799 impB/mucB/samB family C-terminal domain DIR45_22015 PF00817 impB/mucB/samB family DIR45_22025 PF01546 Peptidase family M20/M25/M40 DIR45_22025 PF07687 Peptidase dimerisation domain DIR45_22030 PF13302 Acetyltransferase (GNAT) domain DIR45_22045 PF03734 L,D-transpeptidase catalytic domain DIR45_22050 PF11728 Putative aromatic acid exporter C-terminal domain DIR45_22050 PF06081 Aromatic acid exporter family member 1 DIR45_22055 PF00005 ABC transporter DIR45_22060 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_22065 PF00497 Bacterial extracellular solute-binding proteins, family 3 DIR45_22075 PF06491 Disulphide isomerase DIR45_22080 PF11208 Protein of unknown function (DUF2992) DIR45_22085 PF00293 NUDIX domain DIR45_22085 PF09297 NADH pyrophosphatase zinc ribbon domain DIR45_22090 PF01098 Cell cycle protein DIR45_22100 PF00364 Biotin-requiring enzyme DIR45_22100 PF02817 e3 binding domain DIR45_22100 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DIR45_22105 PF02780 Transketolase, C-terminal domain DIR45_22105 PF02779 Transketolase, pyrimidine binding domain DIR45_22110 PF00676 Dehydrogenase E1 component DIR45_22115 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_22115 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DIR45_22120 PF00871 Acetokinase family DIR45_22125 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DIR45_22125 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DIR45_22130 PF01515 Phosphate acetyl/butaryl transferase DIR45_22140 PF00158 Sigma-54 interaction domain DIR45_22140 PF02954 Bacterial regulatory protein, Fis family DIR45_22140 PF00989 PAS fold DIR45_22150 PF03009 Glycerophosphoryl diester phosphodiesterase family DIR45_22155 PF14174 YycC-like protein DIR45_22165 PF00072 Response regulator receiver domain DIR45_22165 PF08769 Sporulation initiation factor Spo0A C terminal DIR45_22175 PF17820 PDZ domain DIR45_22175 PF05580 SpoIVB peptidase S55 DIR45_22180 PF13476 AAA domain DIR45_22185 PF01316 Arginine repressor, DNA binding domain DIR45_22185 PF02863 Arginine repressor, C-terminal domain DIR45_22190 PF01479 S4 domain DIR45_22190 PF01728 FtsJ-like methyltransferase DIR45_22195 PF02779 Transketolase, pyrimidine binding domain DIR45_22195 PF02780 Transketolase, C-terminal domain DIR45_22195 PF13292 1-deoxy-D-xylulose-5-phosphate synthase DIR45_22200 PF00348 Polyprenyl synthetase DIR45_22205 PF02609 Exonuclease VII small subunit DIR45_22210 PF13742 OB-fold nucleic acid binding domain DIR45_22210 PF02601 Exonuclease VII, large subunit DIR45_22215 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DIR45_22215 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DIR45_22220 PF01029 NusB family DIR45_22225 PF03780 Asp23 family, cell envelope-related function DIR45_22230 PF02785 Biotin carboxylase C-terminal domain DIR45_22230 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain DIR45_22230 PF00289 Biotin carboxylase, N-terminal domain DIR45_22235 PF00364 Biotin-requiring enzyme DIR45_22245 PF12685 SpoIIIAH-like protein DIR45_22255 PF09581 Stage III sporulation protein AF (Spore_III_AF) DIR45_22260 PF09546 Stage III sporulation protein AE (spore_III_AE) DIR45_22265 PF06686 Stage III sporulation protein AC/AD protein family DIR45_22270 PF06686 Stage III sporulation protein AC/AD protein family DIR45_22275 PF09548 Stage III sporulation protein AB (spore_III_AB) DIR45_22300 PF01132 Elongation factor P (EF-P) OB domain DIR45_22300 PF08207 Elongation factor P (EF-P) KOW-like domain DIR45_22300 PF09285 Elongation factor P, C-terminal DIR45_22305 PF00557 Metallopeptidase family M24 DIR45_22305 PF01321 Creatinase/Prolidase N-terminal domain DIR45_22310 PF01220 Dehydroquinase class II DIR45_22315 PF11085 Conserved membrane protein YqhR DIR45_22320 PF07136 Protein of unknown function (DUF1385) DIR45_22330 PF13419 Haloacid dehalogenase-like hydrolase DIR45_22335 PF02742 Iron dependent repressor, metal binding and dimerisation domain DIR45_22335 PF01325 Iron dependent repressor, N-terminal DNA binding domain DIR45_22350 PF03099 Biotin/lipoate A/B protein ligase family DIR45_22355 PF00581 Rhodanese-like domain DIR45_22360 PF00356 Bacterial regulatory proteins, lacI family DIR45_22360 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family DIR45_22370 PF00893 Small Multidrug Resistance protein DIR45_22375 PF00893 Small Multidrug Resistance protein DIR45_22415 PF00005 ABC transporter DIR45_22420 PF00392 Bacterial regulatory proteins, gntR family DIR45_22440 PF02347 Glycine cleavage system P-protein DIR45_22445 PF02347 Glycine cleavage system P-protein DIR45_22450 PF01571 Aminomethyltransferase folate-binding domain DIR45_22450 PF08669 Glycine cleavage T-protein C-terminal barrel domain DIR45_22455 PF00176 SNF2 family N-terminal domain DIR45_22455 PF00271 Helicase conserved C-terminal domain DIR45_22460 PF11079 Bacterial protein YqhG of unknown function DIR45_22485 PF14038 YqzE-like protein DIR45_22490 PF01202 Shikimate kinase DIR45_22515 PF07963 Prokaryotic N-terminal methylation motif DIR45_22525 PF00482 Type II secretion system (T2SS), protein F DIR45_22530 PF00437 Type II/IV secretion system protein DIR45_22540 PF11117 Protein of unknown function (DUF2626) DIR45_22545 PF00375 Sodium:dicarboxylate symporter family DIR45_22580 PF04101 Glycosyltransferase family 28 C-terminal domain DIR45_22580 PF03033 Glycosyltransferase family 28 N-terminal domain DIR45_22590 PF02219 Methylenetetrahydrofolate reductase DIR45_22590 PF02574 Homocysteine S-methyltransferase DIR45_22595 PF01053 Cys/Met metabolism PLP-dependent enzyme DIR45_22600 PF01053 Cys/Met metabolism PLP-dependent enzyme DIR45_22610 PF01022 Bacterial regulatory protein, arsR family DIR45_22620 PF00753 Metallo-beta-lactamase superfamily DIR45_22625 PF10958 Protein of unknown function (DUF2759) DIR45_22630 PF00480 ROK family DIR45_22635 PF06014 Bacterial protein of unknown function (DUF910) DIR45_22640 PF01812 5-formyltetrahydrofolate cyclo-ligase family DIR45_22645 PF00471 Ribosomal protein L33 DIR45_22650 PF00483 Nucleotidyl transferase DIR45_22655 PF01895 PhoU domain DIR45_22660 PF00005 ABC transporter DIR45_22665 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_22670 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_22675 PF12849 PBP superfamily domain DIR45_22685 PF07690 Major Facilitator Superfamily DIR45_22690 PF02777 Iron/manganese superoxide dismutases, C-terminal domain DIR45_22690 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain DIR45_22710 PF04551 GcpE protein DIR45_22715 PF01475 Ferric uptake regulator family DIR45_22720 PF00950 ABC 3 transport family DIR45_22725 PF00005 ABC transporter DIR45_22730 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_22730 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_22735 PF11116 Protein of unknown function (DUF2624) DIR45_22740 PF01261 Xylose isomerase-like TIM barrel DIR45_22745 PF00271 Helicase conserved C-terminal domain DIR45_22745 PF00270 DEAD/DEAH box helicase DIR45_22755 PF02401 LytB protein DIR45_22760 PF01784 NIF3 (NGG1p interacting factor 3) DIR45_22765 PF04816 tRNA (adenine(22)-N(1))-methyltransferase DIR45_22770 PF13442 Cytochrome C oxidase, cbb3-type, subunit III DIR45_22775 PF04545 Sigma-70, region 4 DIR45_22775 PF03979 Sigma-70 factor, region 1.1 DIR45_22775 PF04539 Sigma-70 region 3 DIR45_22775 PF04542 Sigma-70 region 2 DIR45_22775 PF00140 Sigma-70 factor, region 1.2 DIR45_22780 PF08275 DNA primase catalytic core, N-terminal domain DIR45_22780 PF10410 DnaB-helicase binding domain of primase DIR45_22780 PF01807 CHC2 zinc finger DIR45_22795 PF03618 Kinase/pyrophosphorylase DIR45_22800 PF00571 CBS domain DIR45_22800 PF08279 HTH domain DIR45_22805 PF11967 Recombination protein O N terminal DIR45_22805 PF02565 Recombination protein O C terminal DIR45_22815 PF01926 50S ribosome-binding GTPase DIR45_22815 PF07650 KH domain DIR45_22820 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region DIR45_22825 PF01219 Prokaryotic diacylglycerol kinase DIR45_22830 PF02130 Uncharacterized protein family UPF0054 DIR45_22835 PF07698 7TM receptor with intracellular HD hydrolase DIR45_22835 PF01966 HD domain DIR45_22835 PF07697 7TM-HD extracellular DIR45_22840 PF02562 PhoH-like protein DIR45_22845 PF06898 Putative stage IV sporulation protein YqfD DIR45_22855 PF07873 YabP family DIR45_22860 PF09424 Yqey-like protein DIR45_22865 PF01165 Ribosomal protein S21 DIR45_22875 PF04055 Radical SAM superfamily DIR45_22875 PF01938 TRAM domain DIR45_22875 PF00919 Uncharacterized protein family UPF0004 DIR45_22880 PF04452 RNA methyltransferase DIR45_22890 PF00684 DnaJ central domain DIR45_22890 PF01556 DnaJ C terminal domain DIR45_22890 PF00226 DnaJ domain DIR45_22895 PF00012 Hsp70 protein DIR45_22900 PF01025 GrpE DIR45_22905 PF01628 HrcA protein C terminal domain DIR45_22910 PF04055 Radical SAM superfamily DIR45_22910 PF06969 HemN C-terminal domain DIR45_22915 PF01638 HxlR-like helix-turn-helix DIR45_22920 PF03144 Elongation factor Tu domain 2 DIR45_22920 PF00679 Elongation factor G C-terminus DIR45_22920 PF06421 GTP-binding protein LepA C-terminus DIR45_22920 PF00009 Elongation factor Tu GTP binding domain DIR45_22930 PF03418 Germination protease DIR45_22935 PF01649 Ribosomal protein S20 DIR45_22940 PF06144 DNA polymerase III, delta subunit DIR45_22945 PF14141 YqzM-like protein DIR45_22950 PF03772 Competence protein DIR45_22950 PF00753 Metallo-beta-lactamase superfamily DIR45_22950 PF13567 Domain of unknown function (DUF4131) DIR45_22955 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region DIR45_22960 PF10531 SLBB domain DIR45_22965 PF14748 Pyrroline-5-carboxylate reductase dimerisation DIR45_22965 PF03807 NADP oxidoreductase coenzyme F420-dependent DIR45_22970 PF13649 Methyltransferase domain DIR45_22980 PF01966 HD domain DIR45_22985 PF01467 Cytidylyltransferase-like DIR45_22990 PF01985 CRS1 / YhbY (CRM) domain DIR45_22995 PF08501 Shikimate dehydrogenase substrate binding domain DIR45_22995 PF01488 Shikimate / quinate 5-dehydrogenase DIR45_22995 PF18317 Shikimate 5'-dehydrogenase C-terminal domain DIR45_23000 PF01926 50S ribosome-binding GTPase DIR45_23015 PF02666 Phosphatidylserine decarboxylase DIR45_23020 PF04545 Sigma-70, region 4 DIR45_23020 PF04542 Sigma-70 region 2 DIR45_23030 PF16244 Domain of unknown function (DUF4901) DIR45_23035 PF00471 Ribosomal protein L33 DIR45_23040 PF00881 Nitroreductase family DIR45_23045 PF04607 Region found in RelA / SpoT proteins DIR45_23055 PF00245 Alkaline phosphatase DIR45_23065 PF08386 TAP-like protein DIR45_23065 PF00561 alpha/beta hydrolase fold DIR45_23100 PF13860 FlgD Ig-like domain DIR45_23100 PF05922 Peptidase inhibitor I9 DIR45_23100 PF02225 PA domain DIR45_23100 PF00082 Subtilase family DIR45_23105 PF00351 Biopterin-dependent aromatic amino acid hydroxylase DIR45_23115 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_23120 PF07681 DoxX DIR45_23150 PF00005 ABC transporter DIR45_23155 PF01032 FecCD transport family DIR45_23160 PF01497 Periplasmic binding protein DIR45_23165 PF14143 YrhC-like protein DIR45_23170 PF00465 Iron-containing alcohol dehydrogenase DIR45_23170 PF00171 Aldehyde dehydrogenase family DIR45_23175 PF01053 Cys/Met metabolism PLP-dependent enzyme DIR45_23180 PF00291 Pyridoxal-phosphate dependent enzyme DIR45_23185 PF01048 Phosphorylase superfamily DIR45_23190 PF08241 Methyltransferase domain DIR45_23205 PF03717 Penicillin-binding Protein dimerisation domain DIR45_23205 PF00905 Penicillin binding protein transpeptidase domain DIR45_23210 PF03449 Transcription elongation factor, N-terminal DIR45_23210 PF01272 Transcription elongation factor, GreA/GreB, C-term DIR45_23215 PF00485 Phosphoribulokinase / Uridine kinase family DIR45_23235 PF02618 YceG-like family DIR45_23240 PF06949 Protein of unknown function (DUF1292) DIR45_23245 PF03652 Holliday junction resolvase DIR45_23250 PF06135 IreB regulatory phosphoprotein DIR45_23255 PF01411 tRNA synthetases class II (A) DIR45_23255 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain DIR45_23255 PF02272 DHHA1 domain DIR45_23265 PF01594 AI-2E family transporter DIR45_23285 PF18335 ATP-dependent RecD-like DNA helicase SH3 domain DIR45_23285 PF13538 UvrD-like helicase C-terminal domain DIR45_23285 PF14490 Helix-hairpin-helix containing domain DIR45_23300 PF00266 Aminotransferase class-V DIR45_23305 PF02082 Transcriptional regulator DIR45_23310 PF12002 MgsA AAA+ ATPase C terminal DIR45_23310 PF05496 Holliday junction DNA helicase RuvB P-loop domain DIR45_23310 PF16193 AAA C-terminal domain DIR45_23320 PF00899 ThiF family DIR45_23325 PF01336 OB-fold nucleic acid binding domain DIR45_23325 PF02938 GAD domain DIR45_23325 PF00152 tRNA synthetases class II (D, K and N) DIR45_23330 PF03129 Anticodon binding domain DIR45_23330 PF13393 Histidyl-tRNA synthetase DIR45_23345 PF02580 D-Tyr-tRNA(Tyr) deacylase DIR45_23350 PF02824 TGS domain DIR45_23350 PF04607 Region found in RelA / SpoT proteins DIR45_23350 PF13291 ACT domain DIR45_23355 PF00156 Phosphoribosyl transferase domain DIR45_23360 PF17768 RecJ OB domain DIR45_23360 PF01368 DHH family DIR45_23360 PF02272 DHHA1 domain DIR45_23360 PF10141 Single-strand DNA-specific exonuclease, C terminal domain DIR45_23370 PF02355 Protein export membrane protein DIR45_23370 PF07549 SecD/SecF GG Motif DIR45_23375 PF13797 Post-transcriptional regulator DIR45_23380 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_23380 PF01943 Polysaccharide biosynthesis protein DIR45_23385 PF04239 Protein of unknown function (DUF421) DIR45_23395 PF02699 Preprotein translocase subunit DIR45_23400 PF01702 Queuine tRNA-ribosyltransferase DIR45_23405 PF02547 Queuosine biosynthesis protein DIR45_23410 PF11146 Protein of unknown function (DUF2905) DIR45_23415 PF05496 Holliday junction DNA helicase RuvB P-loop domain DIR45_23415 PF05491 RuvB C-terminal winged helix domain DIR45_23415 PF17864 RuvB AAA lid domain DIR45_23420 PF01330 RuvA N terminal domain DIR45_23420 PF07499 RuvA, C-terminal domain DIR45_23425 PF01497 Periplasmic binding protein DIR45_23435 PF00892 EamA-like transporter family DIR45_23440 PF00892 EamA-like transporter family DIR45_23445 PF01022 Bacterial regulatory protein, arsR family DIR45_23460 PF01476 LysM domain DIR45_23465 PF02445 Quinolinate synthetase A protein DIR45_23470 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain DIR45_23470 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain DIR45_23475 PF02910 Fumarate reductase flavoprotein C-term DIR45_23475 PF00890 FAD binding domain DIR45_23480 PF00266 Aminotransferase class-V DIR45_23485 PF08279 HTH domain DIR45_23485 PF02829 3H domain DIR45_23490 PF03473 MOSC domain DIR45_23490 PF03475 3-alpha domain DIR45_23495 PF00800 Prephenate dehydratase DIR45_23495 PF01842 ACT domain DIR45_23500 PF02687 FtsX-like permease family DIR45_23505 PF02687 FtsX-like permease family DIR45_23510 PF00005 ABC transporter DIR45_23520 PF00072 Response regulator receiver domain DIR45_23520 PF00486 Transcriptional regulatory protein, C terminal DIR45_23525 PF09269 Domain of unknown function (DUF1967) DIR45_23525 PF01926 50S ribosome-binding GTPase DIR45_23525 PF01018 GTP1/OBG DIR45_23530 PF14682 Sporulation initiation phospho-transferase B, C-terminal DIR45_23530 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain DIR45_23535 PF01016 Ribosomal L27 protein DIR45_23540 PF04327 Cysteine protease Prp DIR45_23545 PF00829 Ribosomal prokaryotic L21 protein DIR45_23550 PF10150 Ribonuclease E/G family DIR45_23550 PF00575 S1 RNA binding domain DIR45_23555 PF02163 Peptidase family M50 DIR45_23560 PF01551 Peptidase family M23 DIR45_23565 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain DIR45_23570 PF03775 Septum formation inhibitor MinC, C-terminal domain DIR45_23580 PF04085 rod shape-determining protein MreC DIR45_23590 PF04002 RadC-like JAB domain DIR45_23595 PF02545 Maf-like protein DIR45_23610 PF02875 Mur ligase family, glutamate ligase domain DIR45_23610 PF08245 Mur ligase middle domain DIR45_23615 PF08264 Anticodon-binding domain of tRNA DIR45_23615 PF00133 tRNA synthetases class I (I, L, M and V) DIR45_23615 PF10458 Valyl tRNA synthetase tRNA binding arm DIR45_23625 PF01476 LysM domain DIR45_23630 PF00202 Aminotransferase class-III DIR45_23635 PF00490 Delta-aminolevulinic acid dehydratase DIR45_23640 PF02602 Uroporphyrinogen-III synthase HemD DIR45_23645 PF03900 Porphobilinogen deaminase, C-terminal domain DIR45_23645 PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain DIR45_23650 PF01578 Cytochrome C assembly protein DIR45_23655 PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain DIR45_23655 PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain DIR45_23655 PF01488 Shikimate / quinate 5-dehydrogenase DIR45_23660 PF01047 MarR family DIR45_23665 PF02566 OsmC-like protein DIR45_23670 PF01926 50S ribosome-binding GTPase DIR45_23675 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_23675 PF02190 ATP-dependent protease La (LON) substrate-binding domain DIR45_23675 PF05362 Lon protease (S16) C-terminal proteolytic domain DIR45_23680 PF00004 ATPase family associated with various cellular activities (AAA) DIR45_23680 PF05362 Lon protease (S16) C-terminal proteolytic domain DIR45_23685 PF07724 AAA domain (Cdc48 subfamily) DIR45_23685 PF10431 C-terminal, D2-small domain, of ClpB protein DIR45_23685 PF06689 ClpX C4-type zinc finger DIR45_23690 PF05698 Bacterial trigger factor protein (TF) C-terminus DIR45_23690 PF05697 Bacterial trigger factor protein (TF) DIR45_23690 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase DIR45_23710 PF08000 Bacterial PH domain DIR45_23710 PF11724 YvbH-like oligomerisation region DIR45_23735 PF12850 Calcineurin-like phosphoesterase superfamily domain DIR45_23740 PF01725 Ham1 family DIR45_23745 PF03725 3' exoribonuclease family, domain 2 DIR45_23745 PF01138 3' exoribonuclease family, domain 1 DIR45_23750 PF10646 Sporulation and spore germination DIR45_23755 PF01177 Asp/Glu/Hydantoin racemase DIR45_23760 PF07690 Major Facilitator Superfamily DIR45_23770 PF00440 Bacterial regulatory proteins, tetR family DIR45_23785 PF00196 Bacterial regulatory proteins, luxR family DIR45_23790 PF00860 Permease family DIR45_23800 PF07969 Amidohydrolase family DIR45_23805 PF07969 Amidohydrolase family DIR45_23810 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_23820 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_23825 PF00005 ABC transporter DIR45_23825 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_23830 PF08352 Oligopeptide/dipeptide transporter, C-terminal region DIR45_23830 PF00005 ABC transporter DIR45_23840 PF04397 LytTr DNA-binding domain DIR45_23840 PF00072 Response regulator receiver domain DIR45_23855 PF04024 PspC domain DIR45_23860 PF07883 Cupin domain DIR45_23860 PF01381 Helix-turn-helix DIR45_23865 PF13536 Putative multidrug resistance efflux transporter DIR45_23870 PF00230 Major intrinsic protein DIR45_23875 PF02082 Transcriptional regulator DIR45_23885 PF00005 ABC transporter DIR45_23885 PF13732 Domain of unknown function (DUF4162) DIR45_23890 PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) DIR45_23900 PF01618 MotA/TolQ/ExbB proton channel family DIR45_23905 PF02557 D-alanyl-D-alanine carboxypeptidase DIR45_23910 PF03061 Thioesterase superfamily DIR45_23915 PF13183 4Fe-4S dicluster domain DIR45_23915 PF13085 2Fe-2S iron-sulfur cluster binding domain DIR45_23920 PF00890 FAD binding domain DIR45_23920 PF02910 Fumarate reductase flavoprotein C-term DIR45_23925 PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DIR45_23930 PF10702 Protein of unknown function (DUF2507) DIR45_23935 PF02151 UvrB/uvrC motif DIR45_23935 PF08459 UvrC Helix-hairpin-helix N-terminal DIR45_23935 PF01541 GIY-YIG catalytic domain DIR45_23940 PF00085 Thioredoxin DIR45_23945 PF01012 Electron transfer flavoprotein domain DIR45_23945 PF00766 Electron transfer flavoprotein FAD-binding domain DIR45_23950 PF01012 Electron transfer flavoprotein domain DIR45_23955 PF00378 Enoyl-CoA hydratase/isomerase DIR45_23960 PF08359 YsiA-like protein, C-terminal region DIR45_23960 PF00440 Bacterial regulatory proteins, tetR family DIR45_23965 PF13193 AMP-binding enzyme C-terminal domain DIR45_23965 PF00501 AMP-binding enzyme DIR45_23980 PF01497 Periplasmic binding protein DIR45_23985 PF01032 FecCD transport family DIR45_23990 PF05163 DinB family DIR45_24020 PF00005 ABC transporter DIR45_24025 PF00512 His Kinase A (phospho-acceptor) domain DIR45_24025 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_24030 PF00486 Transcriptional regulatory protein, C terminal DIR45_24030 PF00072 Response regulator receiver domain DIR45_24040 PF09962 Uncharacterized conserved protein (DUF2196) DIR45_24045 PF17785 PUA-like domain DIR45_24045 PF10672 S-adenosylmethionine-dependent methyltransferase DIR45_24055 PF03992 Antibiotic biosynthesis monooxygenase DIR45_24060 PF04203 Sortase domain DIR45_24065 PF00005 ABC transporter DIR45_24070 PF01032 FecCD transport family DIR45_24075 PF01497 Periplasmic binding protein DIR45_24080 PF05031 Iron Transport-associated domain DIR45_24090 PF05031 Iron Transport-associated domain DIR45_24095 PF05525 Branched-chain amino acid transport protein DIR45_24100 PF01479 S4 domain DIR45_24100 PF00849 RNA pseudouridylate synthase DIR45_24110 PF01713 Smr domain DIR45_24110 PF00488 MutS domain V DIR45_24115 PF14791 DNA polymerase beta thumb DIR45_24115 PF02811 PHP domain DIR45_24115 PF14716 Helix-hairpin-helix domain DIR45_24120 PF02674 Colicin V production protein DIR45_24125 PF05164 Cell division protein ZapA DIR45_24130 PF01351 Ribonuclease HII DIR45_24130 PF11858 Domain of unknown function (DUF3378) DIR45_24150 PF00152 tRNA synthetases class II (D, K and N) DIR45_24150 PF01336 OB-fold nucleic acid binding domain DIR45_24155 PF03484 tRNA synthetase B5 domain DIR45_24155 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain DIR45_24155 PF01588 Putative tRNA binding domain DIR45_24155 PF03147 Ferredoxin-fold anticodon binding domain DIR45_24155 PF03483 B3/4 domain DIR45_24160 PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain DIR45_24160 PF01409 tRNA synthetases class II core domain (F) DIR45_24165 PF00588 SpoU rRNA Methylase family DIR45_24165 PF08032 RNA 2'-O ribose methyltransferase substrate binding DIR45_24170 PF14098 Small, acid-soluble spore protein I DIR45_24175 PF01966 HD domain DIR45_24200 PF07690 Major Facilitator Superfamily DIR45_24210 PF00440 Bacterial regulatory proteins, tetR family DIR45_24210 PF16859 Tetracyclin repressor-like, C-terminal domain DIR45_24215 PF05343 M42 glutamyl aminopeptidase DIR45_24225 PF00453 Ribosomal protein L20 DIR45_24230 PF01632 Ribosomal protein L35 DIR45_24235 PF05198 Translation initiation factor IF-3, N-terminal domain DIR45_24235 PF00707 Translation initiation factor IF-3, C-terminal domain DIR45_24240 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain DIR45_24240 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_24240 PF02824 TGS domain DIR45_24240 PF03129 Anticodon binding domain DIR45_24245 PF08812 YtxC-like family DIR45_24250 PF01695 IstB-like ATP binding protein DIR45_24250 PF07319 Primosomal protein DnaI N-terminus DIR45_24255 PF07261 Replication initiation and membrane attachment DIR45_24260 PF03477 ATP cone domain DIR45_24265 PF02675 S-adenosylmethionine decarboxylase DIR45_24275 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DIR45_24275 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DIR45_24280 PF01121 Dephospho-CoA kinase DIR45_24285 PF02659 Putative manganese efflux pump DIR45_24290 PF06827 Zinc finger found in FPG and IleRS DIR45_24290 PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain DIR45_24290 PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain DIR45_24295 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain DIR45_24295 PF01367 5'-3' exonuclease, C-terminal SAM fold DIR45_24295 PF00476 DNA polymerase family A DIR45_24300 PF16736 Single Cache-like DIR45_24300 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_24300 PF00512 His Kinase A (phospho-acceptor) domain DIR45_24300 PF00989 PAS fold DIR45_24305 PF00486 Transcriptional regulatory protein, C terminal DIR45_24305 PF00072 Response regulator receiver domain DIR45_24325 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain DIR45_24325 PF00056 lactate/malate dehydrogenase, NAD binding domain DIR45_24330 PF00180 Isocitrate/isopropylmalate dehydrogenase DIR45_24335 PF00285 Citrate synthase, C-terminal domain DIR45_24345 PF04284 Protein of unknown function (DUF441) DIR45_24350 PF01594 AI-2E family transporter DIR45_24355 PF04186 FxsA cytoplasmic membrane protein DIR45_24360 PF02887 Pyruvate kinase, alpha/beta domain DIR45_24360 PF00224 Pyruvate kinase, barrel domain DIR45_24360 PF00391 PEP-utilising enzyme, mobile domain DIR45_24365 PF00365 Phosphofructokinase DIR45_24370 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DIR45_24375 PF01039 Carboxyl transferase domain DIR45_24375 PF17848 Acetyl-coA carboxylase zinc finger domain DIR45_24380 PF00392 Bacterial regulatory proteins, gntR family DIR45_24385 PF00390 Malic enzyme, N-terminal domain DIR45_24385 PF03949 Malic enzyme, NAD binding domain DIR45_24390 PF02811 PHP domain DIR45_24390 PF01336 OB-fold nucleic acid binding domain DIR45_24390 PF14579 Helix-hairpin-helix motif DIR45_24390 PF17657 Bacterial DNA polymerase III alpha subunit finger domain DIR45_24390 PF07733 Bacterial DNA polymerase III alpha NTPase domain DIR45_24395 PF14034 Sporulation protein YtrH DIR45_24405 PF02272 DHHA1 domain DIR45_24405 PF01368 DHH family DIR45_24415 PF14007 YtpI-like protein DIR45_24430 PF00571 CBS domain DIR45_24430 PF07085 DRTGG domain DIR45_24430 PF03061 Thioesterase superfamily DIR45_24430 PF00392 Bacterial regulatory proteins, gntR family DIR45_24445 PF01321 Creatinase/Prolidase N-terminal domain DIR45_24445 PF00557 Metallopeptidase family M24 DIR45_24450 PF11518 Protein of unknown function (DUF3221) DIR45_24485 PF12746 GNAT acetyltransferase DIR45_24490 PF07883 Cupin domain DIR45_24500 PF01381 Helix-turn-helix DIR45_24510 PF05222 Alanine dehydrogenase/PNT, N-terminal domain DIR45_24510 PF01262 Alanine dehydrogenase/PNT, C-terminal domain DIR45_24520 PF00582 Universal stress protein family DIR45_24540 PF00206 Lyase DIR45_24540 PF14698 Argininosuccinate lyase C-terminal DIR45_24545 PF00764 Arginosuccinate synthase DIR45_24570 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_24570 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_24575 PF12787 EcsC protein family DIR45_24590 PF00871 Acetokinase family DIR45_24595 PF02384 N-6 DNA Methylase DIR45_24600 PF08534 Redoxin DIR45_24605 PF09579 Sporulation protein YtfJ (Spore_YtfJ) DIR45_24615 PF01513 ATP-NAD kinase DIR45_24620 PF07969 Amidohydrolase family DIR45_24630 PF00501 AMP-binding enzyme DIR45_24630 PF13193 AMP-binding enzyme C-terminal domain DIR45_24635 PF00269 Small, acid-soluble spore proteins, alpha/beta type DIR45_24640 PF02926 THUMP domain DIR45_24640 PF02568 Thiamine biosynthesis protein (ThiI) DIR45_24645 PF00266 Aminotransferase class-V DIR45_24650 PF06160 Septation ring formation regulator, EzrA DIR45_24655 PF03466 LysR substrate binding domain DIR45_24655 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_24660 PF00892 EamA-like transporter family DIR45_24670 PF13185 GAF domain DIR45_24675 PF01053 Cys/Met metabolism PLP-dependent enzyme DIR45_24685 PF01479 S4 domain DIR45_24685 PF00163 Ribosomal protein S4/S9 N-terminal domain DIR45_24700 PF01479 S4 domain DIR45_24700 PF00579 tRNA synthetases class I (W and Y) DIR45_24710 PF08281 Sigma-70, region 4 DIR45_24710 PF04542 Sigma-70 region 2 DIR45_24725 PF13193 AMP-binding enzyme C-terminal domain DIR45_24725 PF00501 AMP-binding enzyme DIR45_24730 PF00583 Acetyltransferase (GNAT) family DIR45_24735 PF00571 CBS domain DIR45_24740 PF00850 Histone deacetylase domain DIR45_24750 PF00072 Response regulator receiver domain DIR45_24750 PF00486 Transcriptional regulatory protein, C terminal DIR45_24755 PF13426 PAS domain DIR45_24755 PF00512 His Kinase A (phospho-acceptor) domain DIR45_24755 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_24755 PF00672 HAMP domain DIR45_24760 PF12796 Ankyrin repeats (3 copies) DIR45_24765 PF01408 Oxidoreductase family, NAD-binding Rossmann fold DIR45_24770 PF01741 Large-conductance mechanosensitive channel, MscL DIR45_24795 PF00356 Bacterial regulatory proteins, lacI family DIR45_24805 PF07537 CamS sex pheromone cAM373 precursor DIR45_24810 PF11009 Protein of unknown function (DUF2847) DIR45_24820 PF02073 Thermophilic metalloprotease (M29) DIR45_24840 PF13302 Acetyltransferase (GNAT) domain DIR45_24845 PF01225 Mur ligase family, catalytic domain DIR45_24845 PF08245 Mur ligase middle domain DIR45_24845 PF02875 Mur ligase family, glutamate ligase domain DIR45_24855 PF01580 FtsK/SpoIIIE family DIR45_24855 PF17854 FtsK alpha domain DIR45_24855 PF09397 Ftsk gamma domain DIR45_24865 PF14794 Domain of unknown function (DUF4479) DIR45_24865 PF01588 Putative tRNA binding domain DIR45_24870 PF07285 Protein of unknown function (DUF1444) DIR45_24875 PF00085 Thioredoxin DIR45_24880 PF01931 Protein of unknown function DUF84 DIR45_24885 PF05343 M42 glutamyl aminopeptidase DIR45_24895 PF00753 Metallo-beta-lactamase superfamily DIR45_24900 PF02390 Putative methyltransferase DIR45_24905 PF14165 YtzH-like protein DIR45_24910 PF01636 Phosphotransferase enzyme family DIR45_24915 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DIR45_24915 PF00128 Alpha amylase, catalytic domain DIR45_24915 PF17999 Pullulanase N1-terminal domain DIR45_24925 PF02834 LigT like Phosphoesterase DIR45_24930 PF01546 Peptidase family M20/M25/M40 DIR45_24935 PF08220 DeoR-like helix-turn-helix domain DIR45_24940 PF00849 RNA pseudouridylate synthase DIR45_24940 PF01479 S4 domain DIR45_24945 PF14667 Polysaccharide biosynthesis C-terminal domain DIR45_24945 PF01943 Polysaccharide biosynthesis protein DIR45_24955 PF07690 Major Facilitator Superfamily DIR45_24960 PF01022 Bacterial regulatory protein, arsR family DIR45_24965 PF08327 Activator of Hsp90 ATPase homolog 1-like protein DIR45_24980 PF10957 Sporulation protein Cse60 DIR45_24990 PF02559 CarD-like/TRCF domain DIR45_25000 PF06800 Sugar transport protein DIR45_25015 PF02391 MoaE protein DIR45_25020 PF03205 Molybdopterin guanine dinucleotide synthesis protein B DIR45_25025 PF03453 MoeA N-terminal region (domain I and II) DIR45_25025 PF00994 Probable molybdopterin binding domain DIR45_25025 PF03454 MoeA C-terminal region (domain IV) DIR45_25030 PF01967 MoaC family DIR45_25035 PF00899 ThiF family DIR45_25040 PF06463 Molybdenum Cofactor Synthesis C DIR45_25040 PF04055 Radical SAM superfamily DIR45_25060 PF00581 Rhodanese-like domain DIR45_25070 PF00561 alpha/beta hydrolase fold DIR45_25075 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_25080 PF03845 Spore germination protein DIR45_25110 PF13603 Leucyl-tRNA synthetase, Domain 2 DIR45_25110 PF09334 tRNA synthetases class I (M) DIR45_25110 PF08264 Anticodon-binding domain of tRNA DIR45_25110 PF00133 tRNA synthetases class I (I, L, M and V) DIR45_25115 PF07690 Major Facilitator Superfamily DIR45_25120 PF00999 Sodium/hydrogen exchanger family DIR45_25125 PF02080 TrkA-C domain DIR45_25130 PF00589 Phage integrase family DIR45_25140 PF00005 ABC transporter DIR45_25145 PF07786 Protein of unknown function (DUF1624) DIR45_25145 PF04235 Protein of unknown function (DUF418) DIR45_25155 PF10732 Protein of unknown function (DUF2524) DIR45_25160 PF04055 Radical SAM superfamily DIR45_25160 PF16199 Radical_SAM C-terminal domain DIR45_25165 PF06962 Putative rRNA methylase DIR45_25175 PF13732 Domain of unknown function (DUF4162) DIR45_25175 PF00005 ABC transporter DIR45_25185 PF01177 Asp/Glu/Hydantoin racemase DIR45_25205 PF10776 Protein of unknown function (DUF2600) DIR45_25210 PF12146 Serine aminopeptidase, S33 DIR45_25215 PF00132 Bacterial transferase hexapeptide (six repeats) DIR45_25220 PF01569 PAP2 superfamily DIR45_25225 PF00534 Glycosyl transferases group 1 DIR45_25225 PF13439 Glycosyltransferase Family 4 DIR45_25230 PF12804 MobA-like NTP transferase domain DIR45_25235 PF00994 Probable molybdopterin binding domain DIR45_25250 PF02772 S-adenosylmethionine synthetase, central domain DIR45_25250 PF02773 S-adenosylmethionine synthetase, C-terminal domain DIR45_25250 PF00438 S-adenosylmethionine synthetase, N-terminal domain DIR45_25260 PF01293 Phosphoenolpyruvate carboxykinase DIR45_25295 PF01784 NIF3 (NGG1p interacting factor 3) DIR45_25300 PF00989 PAS fold DIR45_25300 PF13188 PAS domain DIR45_25300 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_25300 PF13426 PAS domain DIR45_25300 PF00512 His Kinase A (phospho-acceptor) domain DIR45_25305 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_25305 PF08447 PAS fold DIR45_25305 PF00989 PAS fold DIR45_25305 PF00512 His Kinase A (phospho-acceptor) domain DIR45_25310 PF08386 TAP-like protein DIR45_25310 PF00561 alpha/beta hydrolase fold DIR45_25315 PF00884 Sulfatase DIR45_25340 PF00005 ABC transporter DIR45_25345 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_25370 PF00293 NUDIX domain DIR45_25395 PF02664 S-Ribosylhomocysteinase (LuxS) DIR45_25400 PF01809 Putative membrane protein insertion efficiency factor DIR45_25405 PF00484 Carbonic anhydrase DIR45_25410 PF01654 Cytochrome bd terminal oxidase subunit I DIR45_25415 PF02322 Cytochrome bd terminal oxidase subunit II DIR45_25420 PF10676 Spore germination protein gerPA/gerPF DIR45_25440 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_25440 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_25465 PF04012 PspA/IM30 family DIR45_25485 PF07664 Ferrous iron transport protein B C terminus DIR45_25485 PF17910 FeoB cytosolic helical domain DIR45_25485 PF02421 Ferrous iron transport protein B DIR45_25485 PF07670 Nucleoside recognition DIR45_25495 PF09515 Thiamine transporter protein (Thia_YuaJ) DIR45_25500 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_25500 PF00672 HAMP domain DIR45_25500 PF00512 His Kinase A (phospho-acceptor) domain DIR45_25505 PF00486 Transcriptional regulatory protein, C terminal DIR45_25505 PF00072 Response regulator receiver domain DIR45_25535 PF00781 Diacylglycerol kinase catalytic domain DIR45_25555 PF00248 Aldo/keto reductase family DIR45_25570 PF09335 SNARE associated Golgi protein DIR45_25575 PF00398 Ribosomal RNA adenine dimethylase DIR45_25580 PF02687 FtsX-like permease family DIR45_25585 PF00005 ABC transporter DIR45_25590 PF06445 GyrI-like small molecule binding domain DIR45_25590 PF12833 Helix-turn-helix domain DIR45_25595 PF00486 Transcriptional regulatory protein, C terminal DIR45_25595 PF00072 Response regulator receiver domain DIR45_25600 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_25605 PF02687 FtsX-like permease family DIR45_25610 PF02687 FtsX-like permease family DIR45_25615 PF00005 ABC transporter DIR45_25630 PF02447 GntP family permease DIR45_25645 PF07071 KDGP aldolase DIR45_25650 PF03841 L-seryl-tRNA selenium transferase DIR45_25655 PF01979 Amidohydrolase family DIR45_25670 PF02557 D-alanyl-D-alanine carboxypeptidase DIR45_25675 PF00512 His Kinase A (phospho-acceptor) domain DIR45_25675 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_25680 PF00072 Response regulator receiver domain DIR45_25680 PF00486 Transcriptional regulatory protein, C terminal DIR45_25685 PF13378 Enolase C-terminal domain-like DIR45_25685 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DIR45_25690 PF00501 AMP-binding enzyme DIR45_25690 PF13193 AMP-binding enzyme C-terminal domain DIR45_25695 PF00378 Enoyl-CoA hydratase/isomerase DIR45_25700 PF00561 alpha/beta hydrolase fold DIR45_25705 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DIR45_25705 PF16582 Middle domain of thiamine pyrophosphate DIR45_25705 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DIR45_25710 PF00425 chorismate binding enzyme DIR45_25715 PF01040 UbiA prenyltransferase family DIR45_25720 PF01258 Prokaryotic dksA/traR C4-type zinc finger DIR45_25725 PF00313 'Cold-shock' DNA-binding domain DIR45_25745 PF00343 Carbohydrate phosphorylase DIR45_25750 PF00534 Glycosyl transferases group 1 DIR45_25750 PF08323 Starch synthase catalytic domain DIR45_25755 PF00483 Nucleotidyl transferase DIR45_25760 PF00483 Nucleotidyl transferase DIR45_25765 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DIR45_25765 PF02806 Alpha amylase, C-terminal all-beta domain DIR45_25765 PF00128 Alpha amylase, catalytic domain DIR45_25785 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain DIR45_25785 PF00056 lactate/malate dehydrogenase, NAD binding domain DIR45_25885 PF05697 Bacterial trigger factor protein (TF) DIR45_25885 PF05698 Bacterial trigger factor protein (TF) C-terminus DIR45_25930 PF02308 MgtC family DIR45_25935 PF07885 Ion channel DIR45_25935 PF02254 TrkA-N domain DIR45_25940 PF08868 YugN-like family DIR45_25945 PF00342 Phosphoglucose isomerase DIR45_25955 PF04070 Domain of unknown function (DUF378) DIR45_25960 PF00575 S1 RNA binding domain DIR45_25965 PF00155 Aminotransferase class I and II DIR45_25970 PF01037 Lrp/AsnC ligand binding domain DIR45_25975 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DIR45_25975 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DIR45_25980 PF08386 TAP-like protein DIR45_25980 PF00561 alpha/beta hydrolase fold DIR45_25990 PF00155 Aminotransferase class I and II DIR45_26000 PF08810 Kinase associated protein B DIR45_26005 PF00929 Exonuclease DIR45_26010 PF03600 Citrate transporter DIR45_26030 PF03129 Anticodon binding domain DIR45_26030 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) DIR45_26035 PF03061 Thioesterase superfamily DIR45_26045 PF02632 BioY family DIR45_26055 PF00483 Nucleotidyl transferase DIR45_26060 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DIR45_26060 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain DIR45_26060 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DIR45_26060 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DIR45_26065 PF10372 Bacterial membrane-spanning protein N-terminus DIR45_26065 PF02457 DisA bacterial checkpoint controller nucleotide-binding DIR45_26070 PF00883 Cytosol aminopeptidase family, catalytic domain DIR45_26070 PF02789 Cytosol aminopeptidase family, N-terminal domain DIR45_26075 PF06725 3D domain DIR45_26085 PF00293 NUDIX domain DIR45_26085 PF13344 Haloacid dehalogenase-like hydrolase DIR45_26090 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_26095 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_26105 PF06445 GyrI-like small molecule binding domain DIR45_26120 PF04463 Protein of unknown function (DUF523) DIR45_26140 PF01521 Iron-sulphur cluster biosynthesis DIR45_26145 PF01678 Diaminopimelate epimerase DIR45_26150 PF07293 Protein of unknown function (DUF1450) DIR45_26155 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_26165 PF00664 ABC transporter transmembrane region DIR45_26165 PF00005 ABC transporter DIR45_26165 PF03412 Peptidase C39 family DIR45_26170 PF03649 Uncharacterised protein family (UPF0014) DIR45_26175 PF03831 PhnA domain DIR45_26175 PF08274 PhnA Zinc-Ribbon DIR45_26215 PF07315 Protein of unknown function (DUF1462) DIR45_26220 PF01106 NifU-like domain DIR45_26240 PF04608 Phosphatidylglycerophosphatase A DIR45_26250 PF02525 Flavodoxin-like fold DIR45_26255 PF13344 Haloacid dehalogenase-like hydrolase DIR45_26265 PF01934 Protein of unknown function DUF86 DIR45_26270 PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DIR45_26290 PF06265 Protein of unknown function (DUF1027) DIR45_26295 PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DIR45_26300 PF13411 MerR HTH family regulatory protein DIR45_26300 PF07739 TipAS antibiotic-recognition domain DIR45_26305 PF10086 YhfC intramembrane metalloprotease DIR45_26325 PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family DIR45_26325 PF04055 Radical SAM superfamily DIR45_26330 PF01551 Peptidase family M23 DIR45_26340 PF08827 Domain of unknown function (DUF1805) DIR45_26345 PF02872 5'-nucleotidase, C-terminal domain DIR45_26360 PF03551 Transcriptional regulator PadR-like family DIR45_26365 PF04892 VanZ like family DIR45_26375 PF01458 Uncharacterized protein family (UPF0051) DIR45_26380 PF01592 NifU-like N terminal domain DIR45_26385 PF00266 Aminotransferase class-V DIR45_26390 PF01458 Uncharacterized protein family (UPF0051) DIR45_26395 PF00005 ABC transporter DIR45_26400 PF03180 NLPA lipoprotein DIR45_26405 PF03180 NLPA lipoprotein DIR45_26410 PF00528 Binding-protein-dependent transport system inner membrane component DIR45_26415 PF09383 NIL domain DIR45_26415 PF00005 ABC transporter DIR45_26425 PF00085 Thioredoxin DIR45_26430 PF01751 Toprim domain DIR45_26445 PF01597 Glycine cleavage H-protein DIR45_26450 PF03960 ArsC family DIR45_26505 PF00056 lactate/malate dehydrogenase, NAD binding domain DIR45_26505 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain DIR45_26530 PF00440 Bacterial regulatory proteins, tetR family DIR45_26530 PF13305 Tetracyclin repressor-like, C-terminal domain DIR45_26535 PF00753 Metallo-beta-lactamase superfamily DIR45_26540 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_26540 PF00441 Acyl-CoA dehydrogenase, C-terminal domain DIR45_26540 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_26550 PF00108 Thiolase, N-terminal domain DIR45_26550 PF02803 Thiolase, C-terminal domain DIR45_26555 PF00378 Enoyl-CoA hydratase/isomerase DIR45_26555 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DIR45_26555 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DIR45_26565 PF14115 YuzL-like protein DIR45_26570 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_26570 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_26575 PF01619 Proline dehydrogenase DIR45_26580 PF10835 Protein of unknown function (DUF2573) DIR45_26585 PF01910 Thiamine-binding protein DIR45_26590 PF00672 HAMP domain DIR45_26590 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_26590 PF02743 Cache domain DIR45_26610 PF07690 Major Facilitator Superfamily DIR45_26615 PF13520 Amino acid permease DIR45_26625 PF02096 60Kd inner membrane protein DIR45_26635 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DIR45_26635 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) DIR45_26675 PF09335 SNARE associated Golgi protein DIR45_26685 PF17969 L,D-transpeptidase C-terminal domain DIR45_26685 PF03734 L,D-transpeptidase catalytic domain DIR45_26690 PF00072 Response regulator receiver domain DIR45_26690 PF00486 Transcriptional regulatory protein, C terminal DIR45_26695 PF16736 Single Cache-like DIR45_26695 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_26695 PF00512 His Kinase A (phospho-acceptor) domain DIR45_26695 PF00989 PAS fold DIR45_26705 PF08264 Anticodon-binding domain of tRNA DIR45_26705 PF09334 tRNA synthetases class I (M) DIR45_26715 PF02743 Cache domain DIR45_26715 PF00672 HAMP domain DIR45_26715 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_26720 PF01883 Iron-sulfur cluster assembly protein DIR45_26725 PF02868 Thermolysin metallopeptidase, alpha-helical domain DIR45_26725 PF07504 Fungalysin/Thermolysin Propeptide Motif DIR45_26725 PF03413 Peptidase propeptide and YPEB domain DIR45_26725 PF01447 Thermolysin metallopeptidase, catalytic domain DIR45_26730 PF17954 Quercetinase C-terminal cupin domain DIR45_26730 PF02678 Pirin DIR45_26735 PF01047 MarR family DIR45_26745 PF00999 Sodium/hydrogen exchanger family DIR45_26750 PF02080 TrkA-C domain DIR45_26760 PF01235 Sodium:alanine symporter family DIR45_26765 PF00210 Ferritin-like domain DIR45_26780 PF03641 Possible lysine decarboxylase DIR45_26790 PF00210 Ferritin-like domain DIR45_26800 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_26800 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_26805 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_26805 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_26810 PF01235 Sodium:alanine symporter family DIR45_26815 PF01235 Sodium:alanine symporter family DIR45_26820 PF13460 NAD(P)H-binding DIR45_26850 PF00248 Aldo/keto reductase family DIR45_26855 PF07690 Major Facilitator Superfamily DIR45_26860 PF01638 HxlR-like helix-turn-helix DIR45_26865 PF07849 Protein of unknown function (DUF1641) DIR45_26870 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_26875 PF00579 tRNA synthetases class I (W and Y) DIR45_26875 PF01479 S4 domain DIR45_26880 PF01565 FAD binding domain DIR45_26880 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DIR45_26890 PF17202 Single cache domain 3 DIR45_26890 PF00672 HAMP domain DIR45_26890 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_26900 PF02537 CrcB-like protein, Camphor Resistance (CrcB) DIR45_26905 PF02537 CrcB-like protein, Camphor Resistance (CrcB) DIR45_26920 PF13302 Acetyltransferase (GNAT) domain DIR45_26925 PF06146 Phosphate-starvation-inducible E DIR45_26945 PF00005 ABC transporter DIR45_26950 PF01032 FecCD transport family DIR45_26955 PF01032 FecCD transport family DIR45_26965 PF00072 Response regulator receiver domain DIR45_26965 PF00486 Transcriptional regulatory protein, C terminal DIR45_26975 PF01668 SmpB protein DIR45_26985 PF00773 RNB domain DIR45_26985 PF08206 Ribonuclease B OB domain DIR45_26985 PF17876 Cold shock domain DIR45_26985 PF00575 S1 RNA binding domain DIR45_26990 PF12146 Serine aminopeptidase, S33 DIR45_26995 PF03840 Preprotein translocase SecG subunit DIR45_27000 PF04172 LrgB-like family DIR45_27005 PF03788 LrgA family DIR45_27010 PF01156 Inosine-uridine preferring nucleoside hydrolase DIR45_27110 PF04860 Phage portal protein DIR45_27130 PF02899 Phage integrase, N-terminal SAM-like domain DIR45_27130 PF00589 Phage integrase family DIR45_27135 PF03952 Enolase, N-terminal domain DIR45_27135 PF00113 Enolase, C-terminal TIM barrel domain DIR45_27140 PF06415 BPG-independent PGAM N-terminus (iPGM_N) DIR45_27140 PF01676 Metalloenzyme superfamily DIR45_27145 PF00121 Triosephosphate isomerase DIR45_27150 PF00162 Phosphoglycerate kinase DIR45_27155 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DIR45_27155 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DIR45_27160 PF04198 Putative sugar-binding domain DIR45_27170 PF04963 Sigma-54 factor, core binding domain DIR45_27170 PF04552 Sigma-54, DNA binding domain DIR45_27170 PF00309 Sigma-54 factor, Activator interacting domain (AID) DIR45_27190 PF03862 SpoVAC/SpoVAEB sporulation membrane protein DIR45_27195 PF07451 Stage V sporulation protein AD (SpoVAD) DIR45_27200 PF03862 SpoVAC/SpoVAEB sporulation membrane protein DIR45_27210 PF04239 Protein of unknown function (DUF421) DIR45_27215 PF00574 Clp protease DIR45_27225 PF00381 PTS HPr component phosphorylation site DIR45_27230 PF10298 WhiA N-terminal LAGLIDADG-like domain DIR45_27230 PF14527 WhiA LAGLIDADG-like domain DIR45_27230 PF02650 WhiA C-terminal HTH domain DIR45_27235 PF01933 Uncharacterised protein family UPF0052 DIR45_27240 PF03668 P-loop ATPase protein family DIR45_27245 PF00293 NUDIX domain DIR45_27255 PF07992 Pyridine nucleotide-disulphide oxidoreductase DIR45_27265 PF14602 Hexapeptide repeat of succinyl-transferase DIR45_27270 PF13419 Haloacid dehalogenase-like hydrolase DIR45_27275 PF01790 Prolipoprotein diacylglyceryl transferase DIR45_27280 PF02603 HPr Serine kinase N terminus DIR45_27280 PF07475 HPr Serine kinase C-terminal domain DIR45_27285 PF04020 Mycobacterial 4 TMS phage holin, superfamily IV DIR45_27295 PF00005 ABC transporter DIR45_27295 PF17760 UvrA interaction domain DIR45_27295 PF17755 UvrA DNA-binding domain DIR45_27300 PF12344 Ultra-violet resistance protein B DIR45_27300 PF17757 UvrB interaction domain DIR45_27300 PF00271 Helicase conserved C-terminal domain DIR45_27300 PF04851 Type III restriction enzyme, res subunit DIR45_27300 PF02151 UvrB/uvrC motif DIR45_27305 PF07282 Putative transposase DNA-binding domain DIR45_27305 PF12323 Helix-turn-helix domain DIR45_27305 PF01385 Probable transposase DIR45_27320 PF07739 TipAS antibiotic-recognition domain DIR45_27320 PF13411 MerR HTH family regulatory protein DIR45_27350 PF03601 Conserved hypothetical protein 698 DIR45_27355 PF03466 LysR substrate binding domain DIR45_27355 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_27360 PF09278 MerR, DNA binding DIR45_27360 PF00376 MerR family regulatory protein DIR45_27365 PF03358 NADPH-dependent FMN reductase DIR45_27375 PF01906 Putative heavy-metal-binding DIR45_27380 PF00664 ABC transporter transmembrane region DIR45_27380 PF00005 ABC transporter DIR45_27385 PF17820 PDZ domain DIR45_27390 PF01471 Putative peptidoglycan binding domain DIR45_27390 PF03572 Peptidase family S41 DIR45_27390 PF17820 PDZ domain DIR45_27395 PF18075 FtsX extracellular domain DIR45_27395 PF02687 FtsX-like permease family DIR45_27400 PF00005 ABC transporter DIR45_27405 PF13442 Cytochrome C oxidase, cbb3-type, subunit III DIR45_27420 PF01043 SecA preprotein cross-linking domain DIR45_27420 PF07516 SecA Wing and Scaffold domain DIR45_27420 PF02810 SEC-C motif DIR45_27420 PF07517 SecA DEAD-like domain DIR45_27425 PF02482 Sigma 54 modulation protein / S30EA ribosomal protein DIR45_27425 PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus DIR45_27430 PF00313 'Cold-shock' DNA-binding domain DIR45_27440 PF04851 Type III restriction enzyme, res subunit DIR45_27440 PF00271 Helicase conserved C-terminal domain DIR45_27445 PF00877 NlpC/P60 family DIR45_27445 PF01476 LysM domain DIR45_27450 PF01638 HxlR-like helix-turn-helix DIR45_27460 PF02645 Uncharacterised protein, DegV family COG1307 DIR45_27465 PF01205 Uncharacterized protein family UPF0029 DIR45_27465 PF09186 Domain of unknown function (DUF1949) DIR45_27470 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_27475 PF02350 UDP-N-acetylglucosamine 2-epimerase DIR45_27480 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DIR45_27480 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIR45_27480 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain DIR45_27485 PF00953 Glycosyl transferase family 4 DIR45_27495 PF00874 PRD domain DIR45_27495 PF03610 PTS system fructose IIA component DIR45_27495 PF00158 Sigma-54 interaction domain DIR45_27505 PF02417 Chromate transporter DIR45_27510 PF04794 YdjC-like protein DIR45_27515 PF02056 Family 4 glycosyl hydrolase DIR45_27515 PF11975 Family 4 glycosyl hydrolase C-terminal domain DIR45_27520 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit DIR45_27525 PF02378 Phosphotransferase system, EIIC DIR45_27530 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit DIR45_27540 PF02675 S-adenosylmethionine decarboxylase DIR45_27545 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit DIR45_27550 PF02378 Phosphotransferase system, EIIC DIR45_27555 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit DIR45_27560 PF00375 Sodium:dicarboxylate symporter family DIR45_27570 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DIR45_27580 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family DIR45_27580 PF03466 LysR substrate binding domain DIR45_27600 PF01654 Cytochrome bd terminal oxidase subunit I DIR45_27605 PF02322 Cytochrome bd terminal oxidase subunit II DIR45_27610 PF02040 Arsenical pump membrane protein DIR45_27615 PF13667 ThiC-associated domain DIR45_27615 PF01964 Radical SAM ThiC family DIR45_27620 PF02652 L-lactate permease DIR45_27630 PF09988 Uncharacterized metal-binding protein (DUF2227) DIR45_27645 PF00884 Sulfatase DIR45_27655 PF01063 Amino-transferase class IV DIR45_27665 PF01773 Na+ dependent nucleoside transporter N-terminus DIR45_27665 PF07662 Na+ dependent nucleoside transporter C-terminus DIR45_27685 PF02028 BCCT, betaine/carnitine/choline family transporter DIR45_27695 PF01476 LysM domain DIR45_27695 PF06725 3D domain DIR45_27720 PF04434 SWIM zinc finger DIR45_27725 PF00176 SNF2 family N-terminal domain DIR45_27725 PF00271 Helicase conserved C-terminal domain DIR45_27725 PF12419 SNF2 Helicase protein DIR45_27755 PF04545 Sigma-70, region 4 DIR45_27755 PF04542 Sigma-70 region 2 DIR45_27760 PF04893 Yip1 domain DIR45_27765 PF12704 MacB-like periplasmic core domain DIR45_27765 PF02687 FtsX-like permease family DIR45_27770 PF00005 ABC transporter DIR45_27790 PF07690 Major Facilitator Superfamily DIR45_27805 PF16736 Single Cache-like DIR45_27805 PF00512 His Kinase A (phospho-acceptor) domain DIR45_27805 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_27805 PF00989 PAS fold DIR45_27810 PF00486 Transcriptional regulatory protein, C terminal DIR45_27810 PF00072 Response regulator receiver domain DIR45_27815 PF16363 GDP-mannose 4,6 dehydratase DIR45_27820 PF03816 Cell envelope-related transcriptional attenuator domain DIR45_27830 PF07977 FabA-like domain DIR45_27835 PF02350 UDP-N-acetylglucosamine 2-epimerase DIR45_27840 PF08239 Bacterial SH3 domain DIR45_27840 PF00005 ABC transporter DIR45_27845 PF01061 ABC-2 type transporter DIR45_27850 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIR45_27850 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DIR45_27850 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain DIR45_27895 PF12116 Stage III sporulation protein D DIR45_27910 PF01551 Peptidase family M23 DIR45_27920 PF00005 ABC transporter DIR45_27930 PF08486 Stage II sporulation protein DIR45_27935 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DIR45_27945 PF06612 Protein of unknown function (DUF1146) DIR45_27955 PF00361 Proton-conducting membrane transporter DIR45_27960 PF00361 Proton-conducting membrane transporter DIR45_27965 PF00361 Proton-conducting membrane transporter DIR45_27965 PF01010 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DIR45_27965 PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DIR45_27970 PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DIR45_27975 PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DIR45_27985 PF00146 NADH dehydrogenase DIR45_27990 PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DIR45_27995 PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DIR45_28000 PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit DIR45_28005 PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DIR45_28010 PF00563 EAL domain DIR45_28010 PF00990 Diguanylate cyclase, GGDEF domain DIR45_28010 PF03707 Bacterial signalling protein N terminal repeat DIR45_28025 PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DIR45_28025 PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DIR45_28030 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain DIR45_28030 PF02874 ATP synthase alpha/beta family, beta-barrel domain DIR45_28035 PF00231 ATP synthase DIR45_28040 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain DIR45_28040 PF00306 ATP synthase alpha/beta chain, C terminal domain DIR45_28040 PF02874 ATP synthase alpha/beta family, beta-barrel domain DIR45_28045 PF00213 ATP synthase delta (OSCP) subunit DIR45_28050 PF00430 ATP synthase B/B' CF(0) DIR45_28055 PF00137 ATP synthase subunit C DIR45_28060 PF00119 ATP synthase A chain DIR45_28065 PF03899 ATP synthase I chain DIR45_28085 PF00464 Serine hydroxymethyltransferase DIR45_28090 PF04260 Protein of unknown function (DUF436) DIR45_28095 PF02502 Ribose/Galactose Isomerase DIR45_28100 PF01451 Low molecular weight phosphotyrosine protein phosphatase DIR45_28110 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DIR45_28115 PF07681 DoxX DIR45_28120 PF01613 Flavin reductase like domain DIR45_28135 PF02659 Putative manganese efflux pump DIR45_28140 PF01300 Telomere recombination DIR45_28140 PF03481 Putative GTP-binding controlling metal-binding DIR45_28150 PF09551 Stage II sporulation protein R (spore_II_R) DIR45_28155 PF17827 PrmC N-terminal domain DIR45_28155 PF13847 Methyltransferase domain DIR45_28160 PF00472 RF-1 domain DIR45_28160 PF03462 PCRF domain DIR45_28165 PF00265 Thymidine kinase DIR45_28170 PF01197 Ribosomal protein L31 DIR45_28175 PF07497 Rho termination factor, RNA-binding domain DIR45_28175 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain DIR45_28175 PF07498 Rho termination factor, N-terminal domain DIR45_28180 PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DIR45_28190 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DIR45_28195 PF01116 Fructose-bisphosphate aldolase class-II DIR45_28200 PF00072 Response regulator receiver domain DIR45_28205 PF10740 Domain of unknown function (DUF2529) DIR45_28210 PF00117 Glutamine amidotransferase class-I DIR45_28210 PF06418 CTP synthase N-terminus DIR45_28215 PF05066 HB1, ASXL, restriction endonuclease HTH domain DIR45_28225 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_28225 PF00441 Acyl-CoA dehydrogenase, C-terminal domain DIR45_28225 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_28230 PF00441 Acyl-CoA dehydrogenase, C-terminal domain DIR45_28230 PF02771 Acyl-CoA dehydrogenase, N-terminal domain DIR45_28230 PF02770 Acyl-CoA dehydrogenase, middle domain DIR45_28235 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DIR45_28235 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DIR45_28240 PF02803 Thiolase, C-terminal domain DIR45_28240 PF00108 Thiolase, N-terminal domain DIR45_28245 PF13183 4Fe-4S dicluster domain DIR45_28245 PF02754 Cysteine-rich domain DIR45_28250 PF13091 PLD-like domain DIR45_28255 PF03851 UV-endonuclease UvdE DIR45_28260 PF00990 Diguanylate cyclase, GGDEF domain DIR45_28260 PF00563 EAL domain DIR45_28260 PF03707 Bacterial signalling protein N terminal repeat DIR45_28280 PF00072 Response regulator receiver domain DIR45_28280 PF00196 Bacterial regulatory proteins, luxR family DIR45_28285 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_28285 PF07730 Histidine kinase DIR45_28295 PF00005 ABC transporter DIR45_28300 PF00557 Metallopeptidase family M24 DIR45_28310 PF01473 Putative cell wall binding repeat DIR45_28310 PF02324 Glycosyl hydrolase family 70 DIR45_28320 PF02225 PA domain DIR45_28320 PF04389 Peptidase family M28 DIR45_28340 PF04542 Sigma-70 region 2 DIR45_28340 PF08281 Sigma-70, region 4 DIR45_28345 PF03485 Arginyl tRNA synthetase N terminal domain DIR45_28345 PF05746 DALR anticodon binding domain DIR45_28345 PF00750 tRNA synthetases class I (R) DIR45_28350 PF09148 Domain of unknown function (DUF1934) DIR45_28355 PF02016 LD-carboxypeptidase N-terminal domain DIR45_28355 PF17676 LD-carboxypeptidase C-terminal domain DIR45_28375 PF00491 Arginase family DIR45_28380 PF17284 Spermidine synthase tetramerisation domain DIR45_28385 PF07690 Major Facilitator Superfamily DIR45_28390 PF13411 MerR HTH family regulatory protein DIR45_28395 PF03009 Glycerophosphoryl diester phosphodiesterase family DIR45_28400 PF00905 Penicillin binding protein transpeptidase domain DIR45_28400 PF00912 Transglycosylase DIR45_28410 PF08741 YwhD family DIR45_28415 PF02163 Peptidase family M50 DIR45_28420 PF01361 Tautomerase enzyme DIR45_28425 PF01966 HD domain DIR45_28430 PF01497 Periplasmic binding protein DIR45_28435 PF00005 ABC transporter DIR45_28440 PF01032 FecCD transport family DIR45_28445 PF01032 FecCD transport family DIR45_28450 PF07293 Protein of unknown function (DUF1450) DIR45_28465 PF03099 Biotin/lipoate A/B protein ligase family DIR45_28470 PF01515 Phosphate acetyl/butaryl transferase DIR45_28480 PF00768 D-alanyl-D-alanine carboxypeptidase DIR45_28480 PF07943 Penicillin-binding protein 5, C-terminal domain DIR45_28485 PF07486 Cell Wall Hydrolase DIR45_28490 PF09671 Spore coat protein (Spore_GerQ) DIR45_28495 PF04241 Protein of unknown function (DUF423) DIR45_28505 PF02254 TrkA-N domain DIR45_28505 PF07885 Ion channel DIR45_28510 PF00860 Permease family DIR45_28520 PF12823 Domain of unknown function (DUF3817) DIR45_28525 PF03167 Uracil DNA glycosylase superfamily DIR45_28530 PF12679 ABC-2 family transporter protein DIR45_28535 PF00005 ABC transporter DIR45_28540 PF13472 GDSL-like Lipase/Acylhydrolase family DIR45_28545 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family DIR45_28545 PF00356 Bacterial regulatory proteins, lacI family DIR45_28555 PF03447 Homoserine dehydrogenase, NAD binding domain DIR45_28555 PF00742 Homoserine dehydrogenase DIR45_28555 PF01842 ACT domain DIR45_28560 PF04204 Homoserine O-succinyltransferase DIR45_28565 PF01053 Cys/Met metabolism PLP-dependent enzyme DIR45_28575 PF13419 Haloacid dehalogenase-like hydrolase DIR45_28580 PF00027 Cyclic nucleotide-binding domain DIR45_28585 PF02525 Flavodoxin-like fold DIR45_28590 PF00196 Bacterial regulatory proteins, luxR family DIR45_28590 PF00072 Response regulator receiver domain DIR45_28600 PF08543 Phosphomethylpyrimidine kinase DIR45_28605 PF07694 5TMR of 5TMR-LYT DIR45_28605 PF00990 Diguanylate cyclase, GGDEF domain DIR45_28610 PF04328 Selenoprotein, putative DIR45_28615 PF02554 Carbon starvation protein CstA DIR45_28615 PF13722 5TM C-terminal transporter carbon starvation CstA DIR45_28620 PF04397 LytTr DNA-binding domain DIR45_28620 PF00072 Response regulator receiver domain DIR45_28625 PF07690 Major Facilitator Superfamily DIR45_28630 PF03808 Glycosyl transferase WecB/TagA/CpsF family DIR45_28645 PF03458 UPF0126 domain DIR45_28650 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain DIR45_28660 PF03061 Thioesterase superfamily DIR45_28670 PF00535 Glycosyl transferase family 2 DIR45_28675 PF12848 ABC transporter DIR45_28675 PF00005 ABC transporter DIR45_28705 PF00535 Glycosyl transferase family 2 DIR45_28710 PF00440 Bacterial regulatory proteins, tetR family DIR45_28715 PF00873 AcrB/AcrD/AcrF family DIR45_28720 PF01625 Peptide methionine sulfoxide reductase DIR45_28720 PF01641 SelR domain DIR45_28725 PF01594 AI-2E family transporter DIR45_28730 PF04172 LrgB-like family DIR45_28735 PF03788 LrgA family DIR45_28740 PF00072 Response regulator receiver domain DIR45_28740 PF04397 LytTr DNA-binding domain DIR45_28745 PF13492 GAF domain DIR45_28745 PF07694 5TMR of 5TMR-LYT DIR45_28745 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_28745 PF06580 Histidine kinase DIR45_28750 PF07690 Major Facilitator Superfamily DIR45_28755 PF02028 BCCT, betaine/carnitine/choline family transporter DIR45_28760 PF02898 Nitric oxide synthase, oxygenase domain DIR45_28770 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain DIR45_28770 PF02777 Iron/manganese superoxide dismutases, C-terminal domain DIR45_28780 PF02293 AmiS/UreI family transporter DIR45_28790 PF16363 GDP-mannose 4,6 dehydratase DIR45_28795 PF03006 Haemolysin-III related DIR45_28805 PF00271 Helicase conserved C-terminal domain DIR45_28805 PF00270 DEAD/DEAH box helicase DIR45_28805 PF03880 DbpA RNA binding domain DIR45_28815 PF00478 IMP dehydrogenase / GMP reductase domain DIR45_28820 PF08439 Oligopeptidase F DIR45_28820 PF01432 Peptidase family M3 DIR45_28830 PF02590 Predicted SPOUT methyltransferase DIR45_28840 PF13180 PDZ domain DIR45_28845 PF00753 Metallo-beta-lactamase superfamily DIR45_28855 PF07435 YycH protein DIR45_28860 PF00672 HAMP domain DIR45_28860 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIR45_28860 PF13426 PAS domain DIR45_28860 PF00512 His Kinase A (phospho-acceptor) domain DIR45_28865 PF00486 Transcriptional regulatory protein, C terminal DIR45_28865 PF00072 Response regulator receiver domain DIR45_28890 PF00709 Adenylosuccinate synthetase DIR45_28895 PF00772 DnaB-like helicase N terminal domain DIR45_28895 PF03796 DnaB-like helicase C terminal domain DIR45_28900 PF03948 Ribosomal protein L9, C-terminal domain DIR45_28900 PF01281 Ribosomal protein L9, N-terminal domain DIR45_28905 PF02272 DHHA1 domain DIR45_28905 PF01368 DHH family DIR45_28910 PF09991 Predicted membrane protein (DUF2232) DIR45_28915 PF01084 Ribosomal protein S18 DIR45_28920 PF00436 Single-strand binding protein family DIR45_28925 PF01250 Ribosomal protein S6 DIR45_28930 PF06071 Protein of unknown function (DUF933) DIR45_28930 PF01926 50S ribosome-binding GTPase DIR45_28935 PF06107 Bacterial protein of unknown function (DUF951) DIR45_28940 PF00924 Mechanosensitive ion channel DIR45_28945 PF06866 Protein of unknown function (DUF1256) DIR45_28950 PF17762 HTH domain found in ParB protein DIR45_28950 PF02195 ParB-like nuclease domain DIR45_28955 PF13614 AAA domain DIR45_28960 PF02195 ParB-like nuclease domain DIR45_28960 PF17762 HTH domain found in ParB protein DIR45_28965 PF02527 rRNA small subunit methyltransferase G DIR45_28970 PF01134 Glucose inhibited division protein A DIR45_28970 PF13932 GidA associated domain DIR45_28975 PF12631 MnmE helical domain DIR45_28975 PF01926 50S ribosome-binding GTPase DIR45_28975 PF10396 GTP-binding protein TrmE N-terminus DIR45_28980 PF01424 R3H domain DIR45_28980 PF14804 Jag N-terminus DIR45_28985 PF02096 60Kd inner membrane protein DIR45_28990 PF00825 Ribonuclease P DIR45_28995 PF00468 Ribosomal protein L34 DIR45_29075 PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) DIR45_29170 PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) DIR45_29210 PF08378 Nuclease-related domain DIR45_29230 PF13342 C-terminal repeat of topoisomerase DIR45_29230 PF01751 Toprim domain DIR45_29230 PF01131 DNA topoisomerase DIR45_29240 PF00565 Staphylococcal nuclease homologue DIR45_29255 PF02600 Disulfide bond formation protein DsbB DIR45_29260 PF01022 Bacterial regulatory protein, arsR family DIR45_29265 PF17209 Hfq protein DIR45_29270 PF18801 response regulator aspartate phosphatase H, N terminal DIR45_29295 PF00589 Phage integrase family DIR45_29310 PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DIR45_29335 PF04740 LXG domain of WXG superfamily DIR45_29335 PF14436 Bacterial EndoU nuclease DIR45_29365 PF00589 Phage integrase family DIR45_29365 PF02899 Phage integrase, N-terminal SAM-like domain DIR45_29395 PF07737 Anthrax toxin lethal factor, N- and C-terminal domain DIR45_29395 PF09156 Anthrax toxin lethal factor, middle domain DIR45_29420 PF01022 Bacterial regulatory protein, arsR family DIR45_29425 PF07691 PA14 domain DIR45_29425 PF17476 Clostridial binary toxin B/anthrax toxin PA domain 3 DIR45_29425 PF03495 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DIR45_29425 PF17475 Clostridial binary toxin B/anthrax toxin PA domain 2 DIR45_29445 PF03323 Bacillus/Clostridium GerA spore germination protein DIR45_29450 PF03845 Spore germination protein DIR45_29455 PF00239 Resolvase, N terminal domain DIR45_29455 PF02796 Helix-turn-helix domain of resolvase DIR45_29485 PF00874 PRD domain DIR45_29485 PF05043 Mga helix-turn-helix domain DIR45_29485 PF08279 HTH domain DIR45_29490 PF02660 Glycerol-3-phosphate acyltransferase DIR45_29500 PF00156 Phosphoribosyl transferase domain DIR45_29505 PF00156 Phosphoribosyl transferase domain DIR45_29510 PF07737 Anthrax toxin lethal factor, N- and C-terminal domain DIR45_29510 PF03497 Anthrax toxin LF subunit DIR45_29560 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DIR45_29560 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain DIR45_29560 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIR45_29565 PF00483 Nucleotidyl transferase DIR45_29570 PF00535 Glycosyl transferase family 2 DIR45_29595 PF01569 PAP2 superfamily DIR45_29600 PF00395 S-layer homology domain DIR45_29620 PF04235 Protein of unknown function (DUF418) DIR45_29635 PF10087 Uncharacterized protein conserved in bacteria (DUF2325) DIR45_29760 PF00437 Type II/IV secretion system protein DIR45_29850 PF01580 FtsK/SpoIIIE family DIR45_29850 PF09397 Ftsk gamma domain DIR45_29850 PF17854 FtsK alpha domain DIR45_29850 PF13491 4TM region of DNA translocase FtsK/SpoIIIE DIR45_29875 PF01609 Transposase DDE domain DIR45_29880 PF01609 Transposase DDE domain DIR45_29925 PF04956 TrbC/VIRB2 family DIR45_29950 PF00437 Type II/IV secretion system protein DIR45_29990 PF17631 Family of unknown function (DUF5512) DIR45_30005 PF17362 Family of unknown function DIR45_30025 PF08708 Primase C terminal 1 (PriCT-1) DIR45_30035 PF13614 AAA domain DIR45_30050 PF01520 N-acetylmuramoyl-L-alanine amidase DIR45_30050 PF00395 S-layer homology domain DIR45_30080 PF01906 Putative heavy-metal-binding DIR45_30085 PF02517 CPBP intramembrane metalloprotease DIR45_30090 PF04463 Protein of unknown function (DUF523) DIR45_30095 PF00440 Bacterial regulatory proteins, tetR family DIR45_30105 PF01569 PAP2 superfamily DIR45_30110 PF01569 PAP2 superfamily DIR45_30120 PF05043 Mga helix-turn-helix domain DIR45_30120 PF08280 M protein trans-acting positive regulator (MGA) HTH domain DIR45_30135 PF09587 Bacterial capsule synthesis protein PGA_cap DIR45_30140 PF14102 Capsule biosynthesis CapC DIR45_30145 PF08245 Mur ligase middle domain DIR45_30160 PF01022 Bacterial regulatory protein, arsR family DIR45_30175 PF10502 Signal peptidase, peptidase S26 DIR45_30185 PF09385 Histidine kinase N terminal DIR45_30190 PF00874 PRD domain DIR45_30190 PF08279 HTH domain DIR45_30190 PF05043 Mga helix-turn-helix domain DIR45_30195 PF08279 HTH domain DIR45_30195 PF05043 Mga helix-turn-helix domain DIR45_30195 PF00874 PRD domain DIR45_30205 PF01810 LysE type translocator DIR45_30215 PF08280 M protein trans-acting positive regulator (MGA) HTH domain DIR45_30215 PF05043 Mga helix-turn-helix domain DIR45_30215 PF00874 PRD domain DIR45_30245 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle DIR45_30255 PF13152 Protein of unknown function (DUF3967) DIR45_30255 PF13411 MerR HTH family regulatory protein DIR45_30260 PF11799 impB/mucB/samB family C-terminal domain DIR45_30260 PF11798 IMS family HHH motif DIR45_30260 PF00817 impB/mucB/samB family DIR45_30280 PF17443 Uncharacterized protein pXO2-72 DIR45_30320 PF13154 Protein of unknown function (DUF3991) DIR45_30335 PF18840 Large polyvalent protein associated domain 25 DIR45_30340 PF17630 Family of unknown function (DUF5511) DIR45_30345 PF17633 Family of unknown function (DUF5514) DIR45_30370 PF17632 Family of unknown function (DUF5513) DIR45_30415 PF12696 TraM recognition site of TraD and TraG