locus-tag	class	description
BF27_1	COG0531	amino acid
BF27_100	COG0785	Cytochrome C biogenesis protein
BF27_1002	COG4978	Transcriptional regulator
BF27_1002	COG0789	Transcriptional regulator
BF27_1007	COG3181	Tripartite tricarboxylate transporter family receptor
BF27_1008	COG4565	transcriptional regulatory protein
BF27_1009	COG3290	protein histidine kinase activity
BF27_1010	COG0477	Major facilitator Superfamily
BF27_1016	COG4608	Belongs to the ABC transporter superfamily
BF27_1017	COG0444	Belongs to the ABC transporter superfamily
BF27_1018	COG0444	Belongs to the ABC transporter superfamily
BF27_1019	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF27_1020	COG0601	transmembrane transport
BF27_1027	COG3938	Belongs to the proline racemase family
BF27_1031	COG1363	Peptidase, m42
BF27_1035	COG1024	Enoyl-CoA hydratase
BF27_1038	COG1696	Membrane protein involved in D-alanine export
BF27_104	COG3340	Belongs to the peptidase S51 family
BF27_1041	COG4196	transglutaminase domain protein
BF27_1042	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF27_1044	COG2244	polysaccharide biosynthetic process
BF27_1045	COG0653	protein targeting
BF27_1049	COG0659	secondary active sulfate transmembrane transporter activity
BF27_105	COG0534	Mate efflux family protein
BF27_1052	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF27_1054	COG3409	Peptidoglycan-binding domain 1 protein
BF27_1054	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF27_1056	COG0561	phosphatase activity
BF27_1059	COG3527	Alpha-acetolactate decarboxylase
BF27_1060	COG0028	Belongs to the TPP enzyme family
BF27_1066	COG0189	ligase activity
BF27_1069	COG1126	abc transporter atp-binding protein
BF27_1070	COG0765	amino acid transport
BF27_1071	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF27_1072	COG1132	(ABC) transporter
BF27_1073	COG1132	(ABC) transporter
BF27_1074	COG1132	(ABC) transporter
BF27_1075	COG1012	belongs to the aldehyde dehydrogenase family
BF27_1077	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF27_1078	COG0531	amino acid
BF27_1080	COG0693	protein deglycase activity
BF27_1080	COG0753	catalase activity
BF27_1081	COG0693	protein deglycase activity
BF27_1083	COG2211	Major facilitator Superfamily
BF27_1084	COG4533	DNA binding
BF27_1085	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF27_1087	COG1733	regulation of RNA biosynthetic process
BF27_1088	COG2814	Major facilitator Superfamily
BF27_1089	COG1309	transcriptional regulator
BF27_109	COG0114	fumarate hydratase activity
BF27_1090	COG2076	Multidrug Resistance protein
BF27_1091	COG2076	Multidrug Resistance protein
BF27_1093	COG1522	sequence-specific DNA binding
BF27_1094	COG0697	spore germination
BF27_1097	COG2259	Doxx family
BF27_1099	COG1263	PTS System
BF27_1099	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_11	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_110	COG1757	Na H antiporter
BF27_1101	COG1737	Transcriptional regulator
BF27_1103	COG0475	glutathione-regulated potassium exporter activity
BF27_1104	COG0531	amino acid
BF27_111	COG1216	Glycosyl transferase, family 2
BF27_111	COG0438	transferase activity, transferring glycosyl groups
BF27_1111	COG0586	Pfam SNARE associated Golgi protein
BF27_1118	COG3546	catalase activity
BF27_1119	COG1114	Component of the transport system for branched-chain amino acids
BF27_1122	COG5522	Integral membrane protein (intg_mem_TP0381)
BF27_1124	COG1136	(ABC) transporter
BF27_1125	COG0577	efflux transmembrane transporter activity
BF27_1126	COG1388	LysM domain
BF27_1126	COG3584	3D domain protein
BF27_113	COG0701	Predicted permease
BF27_1130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF27_1131	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF27_1132	COG3711	transcriptional antiterminator
BF27_1132	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF27_1135	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF27_1136	COG0604	alcohol dehydrogenase
BF27_1137	COG1316	TRANSCRIPTIONal
BF27_1139	COG0730	response to heat
BF27_114	COG0523	cobalamin synthesis protein
BF27_1140	COG2210	Belongs to the sulfur carrier protein TusA family
BF27_1142	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_1144	COG0425	Belongs to the sulfur carrier protein TusA family
BF27_1145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_1145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_1146	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_1146	COG0425	Belongs to the sulfur carrier protein TusA family
BF27_1147	COG1937	Protein conserved in bacteria
BF27_1148	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF27_115	COG0697	spore germination
BF27_1153	COG2719	SpoVR family
BF27_1154	COG0778	Nitroreductase
BF27_116	COG1802	Transcriptional regulator
BF27_1161	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF27_1162	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF27_1164	COG1609	Transcriptional regulator
BF27_1165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_1165	COG1263	PTS System
BF27_1166	COG1621	beta-fructofuranosidase activity
BF27_1167	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF27_1169	COG1376	ErfK ybiS ycfS ynhG family protein
BF27_1170	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_1171	COG2252	PERMEase
BF27_1174	COG1846	Transcriptional regulator
BF27_1175	COG2814	Major facilitator Superfamily
BF27_1176	COG2205	protein histidine kinase activity
BF27_1183	COG0351	phosphomethylpyrimidine kinase
BF27_1184	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF27_1186	COG2104	thiamine diphosphate biosynthetic process
BF27_1187	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF27_1188	COG0352	thiamine-phosphate diphosphorylase activity
BF27_1189	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF27_1190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF27_1191	COG1116	anion transmembrane transporter activity
BF27_1192	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF27_1196	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF27_1219	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF27_122	COG0367	asparagine synthase
BF27_1221	COG0581	inorganic phosphate transmembrane transporter activity
BF27_1222	COG0573	inorganic phosphate transmembrane transporter activity
BF27_1223	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF27_1224	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF27_1224	COG1918	ferrous iron import across plasma membrane
BF27_1225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF27_1226	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF27_1228	COG0531	amino acid
BF27_1229	COG0697	spore germination
BF27_1230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF27_1234	COG4990	cell redox homeostasis
BF27_1235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF27_1236	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF27_1239	COG0569	domain protein
BF27_1239	COG0475	glutathione-regulated potassium exporter activity
BF27_124	COG1846	Transcriptional regulator
BF27_1244	COG2252	PERMEase
BF27_1245	COG1113	amino acid transport
BF27_1249	COG1114	Component of the transport system for branched-chain amino acids
BF27_1250	COG3104	oligopeptide transport
BF27_1253	COG1476	TRANSCRIPTIONal
BF27_1254	COG3584	3D domain protein
BF27_1254	COG1388	LysM domain
BF27_1255	COG0840	transmembrane signaling receptor activity
BF27_1256	COG1968	undecaprenyl-diphosphatase activity
BF27_1261	COG3568	Endonuclease Exonuclease Phosphatase
BF27_1264	COG1063	alcohol dehydrogenase
BF27_1268	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF27_1269	COG1879	ABC-type sugar transport system periplasmic component
BF27_1270	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF27_1271	COG1129	ABC transporter
BF27_1273	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF27_1274	COG1609	Transcriptional regulator
BF27_1275	COG0477	Major facilitator Superfamily
BF27_1276	COG0477	Major facilitator Superfamily
BF27_1277	COG1846	Transcriptional regulator
BF27_1278	COG2271	Major facilitator Superfamily
BF27_128	COG0406	alpha-ribazole phosphatase activity
BF27_1280	COG4608	Belongs to the ABC transporter superfamily
BF27_1281	COG0601	transmembrane transport
BF27_1283	COG0747	negative chemotaxis
BF27_1286	COG0659	secondary active sulfate transmembrane transporter activity
BF27_1289	COG5002	protein histidine kinase activity
BF27_1290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF27_1291	COG2378	regulation of single-species biofilm formation
BF27_1296	COG0833	amino acid
BF27_1297	COG0765	amino acid transport
BF27_1298	COG0765	amino acid transport
BF27_1299	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF27_130	COG1686	Belongs to the peptidase S11 family
BF27_1300	COG1126	abc transporter atp-binding protein
BF27_1301	COG1115	amino acid carrier protein
BF27_1302	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF27_1304	COG0697	spore germination
BF27_1307	COG0366	Alpha amylase catalytic
BF27_1308	COG1263	PTS System
BF27_1308	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_1309	COG2188	Transcriptional regulator
BF27_1310	COG0531	amino acid
BF27_1314	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF27_1315	COG0714	Associated with various cellular activities
BF27_1316	COG4548	von Willebrand factor, type A
BF27_1318	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF27_1319	COG0156	8-amino-7-oxononanoate synthase activity
BF27_1320	COG2226	methyltransferase
BF27_1322	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_1323	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_1324	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_1325	COG3104	oligopeptide transport
BF27_1328	COG1620	l-lactate permease
BF27_1329	COG1027	Aspartate ammonia-lyase
BF27_1330	COG1253	flavin adenine dinucleotide binding
BF27_1331	COG0346	lactoylglutathione lyase activity
BF27_1332	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_1333	COG1316	TRANSCRIPTIONal
BF27_1334	COG2720	vancomycin resistance protein
BF27_1338	COG3227	Zinc metalloprotease (Elastase)
BF27_1341	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF27_1342	COG2217	Heavy metal translocating P-type atpase
BF27_1343	COG0640	Transcriptional regulator
BF27_1344	COG0531	amino acid
BF27_1347	COG2427	Protein of unknown function (DUF1641)
BF27_1348	COG3383	formate dehydrogenase (NAD+) activity
BF27_1349	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF27_135	COG1234	tRNA 3'-trailer cleavage
BF27_1350	COG0454	-acetyltransferase
BF27_1350	COG0456	acetyltransferase
BF27_1352	COG0745	RESPONSE REGULATOR receiver
BF27_1353	COG5002	protein histidine kinase activity
BF27_1355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_1358	COG0281	malic enzyme
BF27_1359	COG3493	citrate carrier protein
BF27_136	COG1177	transmembrane transport
BF27_1360	COG4565	transcriptional regulatory protein
BF27_1361	COG3290	protein histidine kinase activity
BF27_1363	COG4990	cell redox homeostasis
BF27_1365	COG5002	protein histidine kinase activity
BF27_1366	COG0745	RESPONSE REGULATOR receiver
BF27_1367	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF27_1369	COG0395	ABC-type sugar transport system, permease component
BF27_137	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF27_1370	COG1175	transmembrane transport
BF27_1371	COG3842	ATPase activity
BF27_1372	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF27_1376	COG2851	Citrate transporter
BF27_1377	COG4565	transcriptional regulatory protein
BF27_1378	COG3290	protein histidine kinase activity
BF27_138	COG3842	ATPase activity
BF27_1381	COG2268	Band 7 protein
BF27_1382	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF27_1384	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF27_1388	COG2766	serine protein kinase
BF27_1391	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF27_1393	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF27_1395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF27_1417	COG0735	belongs to the Fur family
BF27_1418	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF27_1422	COG4555	ABC transporter
BF27_1424	COG0070	glutamate synthase
BF27_1424	COG0067	glutamate synthase
BF27_1424	COG0069	glutamate synthase activity
BF27_1425	COG4129	membrane
BF27_1426	COG1132	(ABC) transporter
BF27_1431	COG1194	a g-specific adenine glycosylase
BF27_1432	COG1988	membrane-bound metal-dependent
BF27_1438	COG1090	epimerase
BF27_1439	COG1228	amidohydrolase
BF27_1443	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF27_1446	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF27_1446	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF27_1449	COG0463	Glycosyl transferase, family 2
BF27_145	COG2329	Antibiotic biosynthesis monooxygenase
BF27_1452	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF27_1453	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_1453	COG1263	PTS System
BF27_1454	COG2066	Belongs to the glutaminase family
BF27_1459	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF27_1460	COG0833	amino acid
BF27_1462	COG3829	transcription factor binding
BF27_1464	COG0101	tRNA pseudouridine synthase activity
BF27_149	COG1309	transcriptional regulator
BF27_1490	COG0582	viral genome integration into host DNA
BF27_1511	COG1484	DNA-dependent DNA replication
BF27_1519	COG1396	sequence-specific DNA binding
BF27_1524	COG0582	viral genome integration into host DNA
BF27_1525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF27_1526	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF27_1531	COG0535	radical SAM domain protein
BF27_1533	COG0387	Pfam Sodium calcium exchanger
BF27_1534	COG3871	stress protein (general stress protein 26)
BF27_1537	COG0586	Pfam SNARE associated Golgi protein
BF27_154	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF27_1541	COG0697	spore germination
BF27_1542	COG2217	Heavy metal translocating P-type atpase
BF27_1543	COG1295	ribonuclease BN
BF27_1545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF27_1548	COG3853	Toxic anion resistance protein (TelA)
BF27_155	COG4786	Flagellar basal body rod
BF27_1551	COG0861	Integral membrane protein TerC family
BF27_1552	COG2310	stress, protein
BF27_1553	COG2310	stress, protein
BF27_1554	COG2310	stress, protein
BF27_1557	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF27_156	COG1419	protein localization to endoplasmic reticulum
BF27_1561	COG2270	Major facilitator Superfamily
BF27_157	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF27_1570	COG0488	(ABC) transporter
BF27_1571	COG1116	anion transmembrane transporter activity
BF27_1574	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF27_1577	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF27_158	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF27_1583	COG2190	(PTS) system
BF27_1583	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_1583	COG1263	PTS System
BF27_1584	COG0366	Alpha amylase catalytic
BF27_1585	COG0840	transmembrane signaling receptor activity
BF27_1586	COG0840	transmembrane signaling receptor activity
BF27_1588	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF27_1589	COG0765	amino acid transport
BF27_1591	COG0723	plastoquinol--plastocyanin reductase activity
BF27_1591	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF27_1592	COG2814	Major facilitator Superfamily
BF27_1593	COG3541	Predicted nucleotidyltransferase
BF27_1597	COG5002	protein histidine kinase activity
BF27_16	COG4166	transmembrane transport
BF27_160	COG1987	bacterial-type flagellum assembly
BF27_1603	COG0166	Belongs to the GPI family
BF27_1606	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_1607	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_1608	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_1609	COG0235	Class ii aldolase
BF27_161	COG1338	Plays a role in the flagellum-specific transport system
BF27_1611	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF27_1612	COG0450	alkyl hydroperoxide reductase
BF27_1615	COG1473	amidohydrolase
BF27_1621	COG4807	Protein conserved in bacteria
BF27_1623	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF27_1624	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF27_1625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_1628	COG2309	aminopeptidase activity
BF27_1629	COG2076	Multidrug Resistance protein
BF27_163	COG1776	CheC inhibitor of MCP methylation
BF27_163	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF27_1630	COG1012	belongs to the aldehyde dehydrogenase family
BF27_1632	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF27_1633	COG0546	phosphoglycolate phosphatase activity
BF27_1634	COG1597	lipid kinase activity
BF27_1638	COG4682	membrane
BF27_1639	COG1846	Transcriptional regulator
BF27_164	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF27_1640	COG0003	Pfam Anion-transporting ATPase
BF27_1643	COG1464	Belongs to the NlpA lipoprotein family
BF27_1644	COG2011	ABC-type metal ion transport system permease component
BF27_1645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF27_1646	COG1335	isochorismatase
BF27_1650	COG4851	CamS sex pheromone cAM373 precursor
BF27_1652	COG0210	DNA helicase
BF27_1657	COG0151	Belongs to the GarS family
BF27_1659	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF27_1661	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF27_1664	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF27_1666	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF27_1667	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF27_1668	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF27_167	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF27_1671	COG0745	RESPONSE REGULATOR receiver
BF27_1672	COG2205	protein histidine kinase activity
BF27_1675	COG1968	undecaprenyl-diphosphatase activity
BF27_1680	COG1215	transferase activity, transferring glycosyl groups
BF27_1685	COG2226	methyltransferase
BF27_1691	COG5002	protein histidine kinase activity
BF27_1693	COG2252	PERMEase
BF27_1697	COG1266	CAAX protease self-immunity
BF27_17	COG1073	alpha beta
BF27_1700	COG0488	(ABC) transporter
BF27_1701	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF27_1702	COG0456	acetyltransferase
BF27_1703	COG1214	PFAM Peptidase M22, glycoprotease
BF27_1704	COG0802	atpase or kinase
BF27_172	COG0457	Tetratricopeptide repeat
BF27_172	COG0463	Glycosyl transferase, family 2
BF27_1745	COG2183	response to ionizing radiation
BF27_1746	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF27_1747	COG0864	Transcriptional regulator
BF27_1748	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF27_1749	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF27_1751	COG4294	response to UV
BF27_1752	COG0457	Tetratricopeptide repeat
BF27_1752	COG0705	Rhomboid family
BF27_1754	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF27_1756	COG2814	Major facilitator Superfamily
BF27_1758	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF27_1759	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF27_1765	COG0561	phosphatase activity
BF27_1766	COG4608	Belongs to the ABC transporter superfamily
BF27_1767	COG0444	Belongs to the ABC transporter superfamily
BF27_1768	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF27_1769	COG0601	transmembrane transport
BF27_1770	COG0747	negative chemotaxis
BF27_1773	COG0488	(ABC) transporter
BF27_1777	COG5298	Protein conserved in bacteria
BF27_1778	COG0084	hydrolase, TatD family'
BF27_178	COG0463	Glycosyl transferase, family 2
BF27_1781	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_1783	COG1609	Transcriptional regulator
BF27_1785	COG0204	Acyl-transferase
BF27_1788	COG0697	spore germination
BF27_1792	COG1910	domain protein
BF27_1793	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF27_1794	COG4149	molybdate abc transporter
BF27_1797	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF27_1798	COG0656	L-ascorbic acid biosynthetic process
BF27_1799	COG4166	transmembrane transport
BF27_180	COG0784	Response regulator, receiver
BF27_180	COG0835	chemotaxis
BF27_1800	COG4166	transmembrane transport
BF27_1803	COG2207	Transcriptional regulator
BF27_1805	COG4166	transmembrane transport
BF27_1806	COG4608	Belongs to the ABC transporter superfamily
BF27_1807	COG0444	Belongs to the ABC transporter superfamily
BF27_1808	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF27_1809	COG0601	transmembrane transport
BF27_1812	COG2814	Major facilitator Superfamily
BF27_1814	COG2271	Major facilitator Superfamily
BF27_1815	COG0277	FAD linked oxidase domain protein
BF27_1818	COG1464	Belongs to the NlpA lipoprotein family
BF27_1819	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF27_1820	COG2011	ABC-type metal ion transport system permease component
BF27_1821	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_1827	COG4946	Tricorn protease homolog
BF27_1827	COG0823	Involved in the tonB-independent uptake of proteins
BF27_1827	COG1506	peptidase
BF27_1828	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF27_1832	COG0596	Alpha beta hydrolase
BF27_1833	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF27_1835	COG4856	YbbR-like protein
BF27_1836	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF27_1854	COG0726	polysaccharide deacetylase
BF27_1855	COG2194	sulfuric ester hydrolase activity
BF27_1857	COG0489	protein tyrosine kinase activity
BF27_1858	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF27_1862	COG0101	tRNA pseudouridine synthase activity
BF27_1863	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF27_1864	COG1122	ATPase activity
BF27_187	COG1157	protein secretion by the type III secretion system
BF27_1870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF27_1872	COG0024	Methionine aminopeptidase
BF27_1874	COG0201	protein transport
BF27_1879	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF27_189	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF27_190	COG1766	The M ring may be actively involved in energy transduction
BF27_1900	COG1358	cellular component organization or biogenesis
BF27_1901	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF27_1903	COG2813	Specifically methylates the guanine in position
BF27_1908	COG0250	Participates in transcription elongation, termination and antitermination
BF27_1909	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF27_191	COG1677	Flagellar hook-basal body complex protein FliE
BF27_1911	COG3688	RNA-binding protein containing a PIN domain
BF27_1912	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF27_1915	COG1045	serine acetyltransferase
BF27_1919	COG4956	integral membrane protein (PIN domain superfamily)
BF27_192	COG1558	bacterial-type flagellum-dependent cell motility
BF27_1921	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF27_1922	COG0542	response to heat
BF27_1924	COG3880	PFAM UvrB UvrC protein
BF27_193	COG1815	bacterial-type flagellum-dependent cell motility
BF27_1931	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF27_1932	COG1396	sequence-specific DNA binding
BF27_1933	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF27_1934	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF27_1935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF27_1936	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF27_1937	COG0512	Glutamine amidotransferase of anthranilate synthase
BF27_1938	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF27_1939	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF27_1942	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF27_1944	COG0037	tRNA processing
BF27_1945	COG2208	phosphoserine phosphatase activity
BF27_1948	COG1098	S1 RNA binding domain
BF27_1952	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF27_1953	COG3956	TIGRFAM MazG family protein
BF27_1954	COG2244	polysaccharide biosynthetic process
BF27_1955	COG2002	toxin-antitoxin pair type II binding
BF27_1956	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF27_1957	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF27_1959	COG0193	aminoacyl-tRNA hydrolase activity
BF27_1960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF27_1963	COG0251	oxidation-reduction process
BF27_1964	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF27_1967	COG4466	Protein conserved in bacteria
BF27_197	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF27_1970	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF27_1971	COG0084	hydrolase, TatD family'
BF27_1972	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_1972	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_1973	COG2002	toxin-antitoxin pair type II binding
BF27_1974	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF27_1976	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF27_1978	COG1774	PSP1 C-terminal conserved region
BF27_1979	COG0470	DNA polymerase III
BF27_198	COG1256	bacterial-type flagellum assembly
BF27_1981	COG1982	Orn Lys Arg decarboxylase major
BF27_1993	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF27_1994	COG0590	tRNA wobble adenosine to inosine editing
BF27_1995	COG1335	isochorismatase
BF27_1996	COG1428	Deoxynucleoside kinase
BF27_1997	COG1428	Deoxynucleoside kinase
BF27_2	COG0531	amino acid
BF27_2003	COG1686	Belongs to the peptidase S11 family
BF27_2004	COG0516	GMP reductase activity
BF27_2004	COG0517	IMP dehydrogenase activity
BF27_2012	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF27_2013	COG0187	DNA topoisomerase II activity
BF27_2015	COG2501	S4 domain
BF27_2016	COG0592	DNA-directed DNA polymerase activity
BF27_202	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF27_2020	COG0706	membrane insertase activity
BF27_2021	COG1847	R3H domain protein
BF27_2022	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF27_2026	COG1192	Involved in chromosome partitioning
BF27_2027	COG1475	DNA binding
BF27_2029	COG0668	transmembrane transport
BF27_2030	COG4481	Protein conserved in bacteria
BF27_2031	COG0012	GTP binding
BF27_2033	COG0629	single-stranded DNA binding
BF27_2035	COG4241	membrane
BF27_2036	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF27_2038	COG0305	Participates in initiation and elongation during chromosome replication
BF27_2044	COG0745	RESPONSE REGULATOR receiver
BF27_2045	COG5002	protein histidine kinase activity
BF27_2046	COG4863	YycH protein
BF27_2047	COG4853	Protein conserved in bacteria
BF27_2048	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF27_2049	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF27_205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF27_205	COG1776	CheC inhibitor of MCP methylation
BF27_2053	COG1164	Oligoendopeptidase f
BF27_2058	COG1272	protein, Hemolysin III
BF27_2059	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF27_206	COG0643	Histidine kinase
BF27_206	COG2198	Histidine kinase
BF27_2063	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF27_2064	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF27_2065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF27_2066	COG2814	Major facilitator Superfamily
BF27_2067	COG3275	phosphorelay sensor kinase activity
BF27_2068	COG3279	Response regulator of the LytR AlgR family
BF27_207	COG2201	protein-glutamate methylesterase activity
BF27_2071	COG0628	permease
BF27_2072	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF27_2072	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF27_2073	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF27_2074	COG1309	transcriptional regulator
BF27_2075	COG0463	Glycosyl transferase, family 2
BF27_208	COG1360	Flagellar Motor Protein
BF27_2080	COG0488	(ABC) transporter
BF27_2083	COG1607	acyl-coa hydrolase
BF27_2085	COG0840	transmembrane signaling receptor activity
BF27_209	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF27_2090	COG0477	Major facilitator Superfamily
BF27_2091	COG3279	Response regulator of the LytR AlgR family
BF27_2092	COG1966	Carbon starvation protein
BF27_2093	COG2879	small protein
BF27_2094	COG3706	GGDEF domain
BF27_2095	COG0351	phosphomethylpyrimidine kinase
BF27_2096	COG2203	Gaf domain
BF27_2096	COG4585	Histidine kinase
BF27_2097	COG4585	Histidine kinase
BF27_2097	COG2203	Gaf domain
BF27_2098	COG2197	response regulator
BF27_21	COG0427	acetyl-CoA hydrolase
BF27_2100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF27_2101	COG1011	Hydrolase
BF27_2105	COG0460	homoserine dehydrogenase
BF27_2107	COG1609	Transcriptional regulator
BF27_2108	COG2755	lipolytic protein G-D-S-L family
BF27_2109	COG1131	(ABC) transporter
BF27_211	COG1923	regulation of RNA biosynthetic process
BF27_2110	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF27_2112	COG2814	Major facilitator Superfamily
BF27_2113	COG0561	phosphatase activity
BF27_2114	COG2233	PERMEase
BF27_2115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF27_2117	COG2363	Small membrane protein
BF27_2119	COG3773	Cell wall hydrolase
BF27_2122	COG0280	phosphate acetyltransferase
BF27_2123	COG0095	Lipoate-protein ligase
BF27_2127	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_2128	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_2129	COG1120	ATPase activity
BF27_2130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_2131	COG1078	dGTPase activity
BF27_2133	COG1994	Peptidase M50
BF27_2135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF27_2136	COG0584	glycerophosphoryl diester phosphodiesterase
BF27_2137	COG0789	Transcriptional regulator
BF27_2138	COG2814	Major facilitator Superfamily
BF27_2139	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF27_2140	COG0010	Belongs to the arginase family
BF27_2143	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF27_2144	COG4506	Protein conserved in bacteria
BF27_2146	COG1595	DNA-templated transcription, initiation
BF27_2150	COG2234	aminopeptidase activity
BF27_2153	COG0024	Methionine aminopeptidase
BF27_2154	COG1131	(ABC) transporter
BF27_2155	COG0842	Transport permease protein
BF27_2156	COG4585	Histidine kinase
BF27_2157	COG2197	response regulator
BF27_2161	COG3300	MHYT domain
BF27_2161	COG5001	Diguanylate cyclase
BF27_2163	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF27_2164	COG0247	lactate metabolic process
BF27_2164	COG2181	nitrate reductase activity
BF27_2165	COG0183	Belongs to the thiolase family
BF27_2166	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF27_2167	COG1960	acyl-CoA dehydrogenase activity
BF27_2168	COG1960	acyl-CoA dehydrogenase activity
BF27_2172	COG4821	SIS domain
BF27_2175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF27_2176	COG1494	fructose-1,6-bisphosphatase
BF27_2177	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF27_2180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF27_2181	COG2890	protein-(glutamine-N5) methyltransferase activity
BF27_2184	COG0009	L-threonylcarbamoyladenylate synthase
BF27_2187	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF27_2188	COG2259	Doxx family
BF27_2189	COG2190	(PTS) system
BF27_2191	COG0698	ribose 5-phosphate isomerase
BF27_2197	COG0356	it plays a direct role in the translocation of protons across the membrane
BF27_22	COG3279	Response regulator of the LytR AlgR family
BF27_2207	COG3300	MHYT domain
BF27_2207	COG5001	Diguanylate cyclase
BF27_2208	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF27_2210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF27_2211	COG0649	NAD binding
BF27_2214	COG0839	Belongs to the complex I subunit 6 family
BF27_2216	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF27_2217	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF27_2218	COG1007	ATP synthesis coupled electron transport
BF27_2219	COG4836	Membrane
BF27_2221	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF27_2222	COG2385	sporulation resulting in formation of a cellular spore
BF27_2223	COG3279	Response regulator of the LytR AlgR family
BF27_2226	COG0739	heme binding
BF27_2228	COG1609	Transcriptional regulator
BF27_223	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF27_2236	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF27_2237	COG1682	transport, permease protein
BF27_2238	COG1134	teichoic acid transport
BF27_2239	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF27_224	COG2323	membrane
BF27_2243	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF27_2244	COG0745	RESPONSE REGULATOR receiver
BF27_2245	COG5002	protein histidine kinase activity
BF27_2252	COG1136	(ABC) transporter
BF27_2253	COG0577	efflux transmembrane transporter activity
BF27_2255	COG1191	sigma factor activity
BF27_226	COG0789	Transcriptional regulator
BF27_226	COG4978	Transcriptional regulator
BF27_2261	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF27_2262	COG4715	Zinc finger, swim domain protein
BF27_2267	COG1388	LysM domain
BF27_2267	COG3584	3D domain protein
BF27_2268	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF27_227	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF27_2270	COG1215	transferase activity, transferring glycosyl groups
BF27_2272	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_2273	COG0791	NLP P60 protein
BF27_2273	COG1388	LysM domain
BF27_2276	COG1368	sulfuric ester hydrolase activity
BF27_2279	COG2389	metal-binding protein
BF27_228	COG0475	glutathione-regulated potassium exporter activity
BF27_2281	COG1620	l-lactate permease
BF27_2283	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF27_2284	COG1294	oxidase, subunit
BF27_2285	COG1271	oxidase subunit
BF27_2288	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF27_2289	COG0583	DNA-binding transcription factor activity
BF27_2290	COG1511	domain protein
BF27_2291	COG0346	lactoylglutathione lyase activity
BF27_2293	COG1301	dicarboxylic acid transport
BF27_2294	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF27_2296	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF27_2297	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF27_2298	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF27_230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF27_2300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF27_2301	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF27_2302	COG1486	melibiose metabolic process
BF27_2303	COG3394	polysaccharide catabolic process
BF27_2306	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF27_2306	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF27_2308	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF27_231	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF27_2311	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF27_2312	COG1316	TRANSCRIPTIONal
BF27_2313	COG1739	Uncharacterized protein family UPF0029
BF27_2314	COG1307	EDD domain protein, DegV family
BF27_2315	COG1733	regulation of RNA biosynthetic process
BF27_2316	COG0791	NLP P60 protein
BF27_2316	COG1388	LysM domain
BF27_2317	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF27_2318	COG1040	competence protein
BF27_2319	COG1278	Cold shock
BF27_232	COG3162	membrane
BF27_2320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF27_2321	COG0653	protein targeting
BF27_2322	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF27_2324	COG2884	Cell division ATP-binding protein ftsE
BF27_2325	COG2177	Part of the ABC transporter FtsEX involved in
BF27_2326	COG0793	Belongs to the peptidase S41A family
BF27_2326	COG3409	Peptidoglycan-binding domain 1 protein
BF27_2327	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF27_2328	COG1132	(ABC) transporter
BF27_2331	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF27_2333	COG0583	DNA-binding transcription factor activity
BF27_2334	COG2855	membrane
BF27_2339	COG0789	Transcriptional regulator
BF27_2343	COG0556	nucleotide-excision repair
BF27_2344	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF27_2346	COG1950	PFAM Membrane protein of
BF27_235	COG1280	lysine exporter protein (LysE YggA)
BF27_2350	COG0110	maltose O-acetyltransferase activity
BF27_2351	COG0457	Tetratricopeptide repeat
BF27_2352	COG0492	ferredoxin-NADP+ reductase activity
BF27_2354	COG1051	belongs to the nudix hydrolase family
BF27_2356	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF27_2358	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF27_2360	COG2323	membrane
BF27_2363	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_2368	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF27_2371	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF27_2373	COG0149	triose-phosphate isomerase activity
BF27_2376	COG4974	Belongs to the 'phage' integrase family
BF27_2380	COG4695	Portal protein
BF27_2399	COG1346	cytolysis
BF27_2400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF27_2401	COG1647	Serine aminopeptidase, S33
BF27_2402	COG0557	exoribonuclease II activity
BF27_2411	COG3223	Belongs to the PsiE family
BF27_2412	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_2415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF27_2416	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF27_2418	COG0840	transmembrane signaling receptor activity
BF27_2418	COG3290	protein histidine kinase activity
BF27_2420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF27_2421	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF27_2422	COG1252	NADH dehydrogenase
BF27_2424	COG1733	regulation of RNA biosynthetic process
BF27_2425	COG2814	Major facilitator Superfamily
BF27_2426	COG0656	L-ascorbic acid biosynthetic process
BF27_243	COG0328	RNA-DNA hybrid ribonuclease activity
BF27_2430	COG2910	NAD(P)H-binding
BF27_2431	COG1115	amino acid carrier protein
BF27_2432	COG1115	amino acid carrier protein
BF27_2433	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_2434	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_2436	COG2311	Membrane
BF27_2439	COG1611	Belongs to the LOG family
BF27_2442	COG0783	Belongs to the Dps family
BF27_2443	COG1115	amino acid carrier protein
BF27_2444	COG0490	domain, Protein
BF27_2445	COG0475	glutathione-regulated potassium exporter activity
BF27_2448	COG1741	Belongs to the pirin family
BF27_2449	COG3227	Zinc metalloprotease (Elastase)
BF27_2450	COG2151	metal-sulfur cluster biosynthetic enzyme
BF27_2453	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_2455	COG5002	protein histidine kinase activity
BF27_2456	COG0745	RESPONSE REGULATOR receiver
BF27_2457	COG1376	ErfK ybiS ycfS ynhG family protein
BF27_2459	COG0586	Pfam SNARE associated Golgi protein
BF27_2466	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_2468	COG0706	membrane insertase activity
BF27_247	COG0454	-acetyltransferase
BF27_2470	COG0531	amino acid
BF27_2471	COG2814	Major facilitator Superfamily
BF27_2476	COG0840	transmembrane signaling receptor activity
BF27_2477	COG0011	TIGRFAM Protein of
BF27_2480	COG1686	Belongs to the peptidase S11 family
BF27_2482	COG1024	Enoyl-CoA hydratase
BF27_2482	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF27_2483	COG0183	Belongs to the thiolase family
BF27_2484	COG1960	acyl-CoA dehydrogenase activity
BF27_2485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_2486	COG1309	transcriptional regulator
BF27_2491	COG0039	L-malate dehydrogenase activity
BF27_2500	COG1393	Belongs to the ArsC family
BF27_2502	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF27_2503	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF27_2505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF27_2506	COG2011	ABC-type metal ion transport system permease component
BF27_2507	COG1464	Belongs to the NlpA lipoprotein family
BF27_2508	COG1464	Belongs to the NlpA lipoprotein family
BF27_2509	COG0396	ATPase activity
BF27_2510	COG0719	Fe-S assembly protein
BF27_2511	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF27_2512	COG0822	iron-sulfur transferase activity
BF27_2513	COG0719	Fe-S assembly protein
BF27_2515	COG1695	Transcriptional regulator
BF27_2516	COG0737	Belongs to the 5'-nucleotidase family
BF27_2517	COG3377	Domain of unknown function (DUF1805)
BF27_2519	COG0739	heme binding
BF27_2524	COG4377	Putative membrane peptidase family (DUF2324)
BF27_2525	COG0789	Transcriptional regulator
BF27_2527	COG4470	Protein conserved in bacteria
BF27_2530	COG1494	fructose-1,6-bisphosphatase
BF27_2531	COG2445	Protein of unknown function DUF86
BF27_2533	COG0647	UMP catabolic process
BF27_2534	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF27_2536	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF27_2537	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF27_2539	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF27_2540	COG4837	Protein of unknown function (DUF1462)
BF27_2548	COG2824	Alkylphosphonate utilization operon protein PhnA
BF27_2549	COG0390	transport system, permease component
BF27_2550	COG2274	protein secretion by the type I secretion system
BF27_2551	COG1252	NADH dehydrogenase
BF27_2554	COG0316	Belongs to the HesB IscA family
BF27_2557	COG1683	Conserved Protein
BF27_2560	COG3708	Transcriptional regulator
BF27_2563	COG1252	NADH dehydrogenase
BF27_2566	COG3584	3D domain protein
BF27_2569	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF27_2570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF27_2572	COG1268	BioY protein
BF27_2574	COG2050	protein possibly involved in aromatic compounds catabolism
BF27_2575	COG0423	glycine-tRNA ligase activity
BF27_2578	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF27_2579	COG5018	Exonuclease
BF27_2583	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF27_2585	COG2267	carboxylic ester hydrolase activity
BF27_2586	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF27_2587	COG1522	sequence-specific DNA binding
BF27_2588	COG0436	Aminotransferase
BF27_2589	COG1098	S1 RNA binding domain
BF27_2590	COG2155	Conserved Protein
BF27_2591	COG0166	Belongs to the GPI family
BF27_2592	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF27_2594	COG1285	pathogenesis
BF27_26	COG2814	Major facilitator Superfamily
BF27_260	COG4824	toxin secretion phage lysis holin
BF27_2602	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF27_2620	COG0039	L-malate dehydrogenase activity
BF27_2622	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF27_2623	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF27_2624	COG0297	glycogen (starch) synthase activity
BF27_2625	COG0058	SHG alpha-glucan phosphorylase activity
BF27_2629	COG1278	Cold shock
BF27_2630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF27_2631	COG1575	Belongs to the MenA family. Type 1 subfamily
BF27_2632	COG1169	isochorismate synthase
BF27_2633	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF27_2634	COG0596	Alpha beta hydrolase
BF27_2635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF27_2637	COG4948	Mandelate Racemase Muconate Lactonizing
BF27_2644	COG3964	amidohydrolase
BF27_2651	COG0577	efflux transmembrane transporter activity
BF27_2652	COG1136	(ABC) transporter
BF27_2653	COG0577	efflux transmembrane transporter activity
BF27_2654	COG0577	efflux transmembrane transporter activity
BF27_2655	COG2205	protein histidine kinase activity
BF27_2656	COG0745	RESPONSE REGULATOR receiver
BF27_2657	COG2207	Transcriptional regulator
BF27_2657	COG3708	Transcriptional regulator
BF27_2658	COG1136	(ABC) transporter
BF27_2659	COG0577	efflux transmembrane transporter activity
BF27_2661	COG0586	Pfam SNARE associated Golgi protein
BF27_2668	COG1597	lipid kinase activity
BF27_2674	COG0745	RESPONSE REGULATOR receiver
BF27_2675	COG5002	protein histidine kinase activity
BF27_2682	COG1842	Phage shock protein A
BF27_2687	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_2691	COG1294	oxidase, subunit
BF27_2692	COG1271	oxidase subunit
BF27_2694	COG0288	reversible hydration of carbon dioxide
BF27_2699	COG0494	nUDIX hydrolase
BF27_2701	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF27_2705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF27_2706	COG1116	anion transmembrane transporter activity
BF27_2707	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF27_2710	COG1368	sulfuric ester hydrolase activity
BF27_2711	COG2267	carboxylic ester hydrolase activity
BF27_2712	COG4191	Histidine kinase
BF27_2713	COG5002	protein histidine kinase activity
BF27_2714	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF27_2724	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF27_2726	COG0438	transferase activity, transferring glycosyl groups
BF27_2727	COG0671	phosphoesterase, PA-phosphatase related
BF27_2728	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF27_2729	COG2267	carboxylic ester hydrolase activity
BF27_2733	COG1794	racemase activity, acting on amino acids and derivatives
BF27_2735	COG1131	(ABC) transporter
BF27_2736	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF27_2737	COG1242	4 iron, 4 sulfur cluster binding
BF27_2741	COG1136	(ABC) transporter
BF27_2743	COG0582	viral genome integration into host DNA
BF27_2744	COG0490	domain, Protein
BF27_2745	COG0475	glutathione-regulated potassium exporter activity
BF27_2746	COG2814	Major facilitator Superfamily
BF27_2754	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF27_2756	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_276	COG1802	Transcriptional regulator
BF27_276	COG4626	Terminase
BF27_2760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF27_2761	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF27_2763	COG0303	'Molybdopterin
BF27_2764	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF27_2765	COG0314	molybdopterin synthase activity
BF27_2770	COG1329	Transcriptional regulator
BF27_2774	COG3832	glyoxalase III activity
BF27_2776	COG2814	Major facilitator Superfamily
BF27_2778	COG2081	HI0933 family
BF27_2779	COG2244	polysaccharide biosynthetic process
BF27_2780	COG1187	pseudouridine synthase activity
BF27_2781	COG1349	DNA-binding transcription factor activity
BF27_2782	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF27_2784	COG1523	belongs to the glycosyl hydrolase 13 family
BF27_2785	COG0510	thiamine kinase activity
BF27_2788	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_2790	COG1363	Peptidase, m42
BF27_2791	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF27_2792	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF27_2793	COG4848	Belongs to the UPF0354 family
BF27_2794	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_2796	COG1674	ftsk spoiiie
BF27_2799	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_2803	COG2309	aminopeptidase activity
BF27_2805	COG3118	belongs to the thioredoxin family
BF27_2806	COG4851	CamS sex pheromone cAM373 precursor
BF27_2807	COG1609	Transcriptional regulator
BF27_2814	COG0666	response to abiotic stimulus
BF27_2816	COG0745	RESPONSE REGULATOR receiver
BF27_2818	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF27_2819	COG0517	IMP dehydrogenase activity
BF27_2820	COG0454	-acetyltransferase
BF27_2821	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF27_2823	COG1595	DNA-templated transcription, initiation
BF27_2825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF27_2829	COG0626	cystathionine gamma-synthase activity
BF27_2830	COG1956	GAF domain-containing protein
BF27_2831	COG1309	transcriptional regulator
BF27_2832	COG0697	spore germination
BF27_2833	COG0583	DNA-binding transcription factor activity
BF27_2835	COG1104	cysteine desulfurase activity
BF27_2838	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF27_2840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF27_2841	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF27_2843	COG3874	Sporulation protein YtfJ
BF27_2844	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF27_2845	COG0827	DNA restriction-modification system
BF27_2846	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF27_2850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_2859	COG0589	response to stress
BF27_2860	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_2863	COG1476	TRANSCRIPTIONal
BF27_2865	COG0662	Cupin 2, conserved barrel domain protein
BF27_2866	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_2873	COG0006	proline dipeptidase activity
BF27_2876	COG4109	DRTGG domain
BF27_2880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF27_2883	COG0587	DNA-directed DNA polymerase activity
BF27_2884	COG0281	malic enzyme
BF27_2885	COG1725	Transcriptional regulator
BF27_2890	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF27_2891	COG0628	permease
BF27_2893	COG0372	Belongs to the citrate synthase family
BF27_2894	COG0538	isocitrate dehydrogenase activity
BF27_2898	COG0745	RESPONSE REGULATOR receiver
BF27_2899	COG5002	protein histidine kinase activity
BF27_2900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF27_2900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF27_2901	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF27_2902	COG1971	Probably functions as a manganese efflux pump
BF27_2903	COG0237	dephospho-CoA kinase activity
BF27_2904	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF27_2905	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF27_2907	COG3611	Membrane attachment protein
BF27_2908	COG1484	DNA-dependent DNA replication
BF27_2910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF27_2911	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF27_2915	COG1363	Peptidase, m42
BF27_2916	COG1309	transcriptional regulator
BF27_2917	COG1566	PFAM secretion protein HlyD family protein
BF27_2918	COG2814	Major facilitator Superfamily
BF27_292	COG0662	Cupin 2, conserved barrel domain protein
BF27_2923	COG1418	mRNA catabolic process
BF27_2925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF27_2927	COG0072	phenylalanine-tRNA ligase activity
BF27_2927	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_2928	COG0017	Asparaginyl-tRNA synthetase
BF27_2934	COG1286	toxin biosynthetic process
BF27_2935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF27_2935	COG1796	DNA polymerase
BF27_2938	COG1187	pseudouridine synthase activity
BF27_2939	COG1114	Component of the transport system for branched-chain amino acids
BF27_2940	COG5386	Cell surface protein
BF27_2942	COG5386	Cell surface protein
BF27_2945	COG1120	ATPase activity
BF27_2946	COG4509	Sortase family
BF27_2949	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF27_2950	COG4895	conserved protein (DUF2196)
BF27_2952	COG0745	RESPONSE REGULATOR receiver
BF27_2953	COG2205	protein histidine kinase activity
BF27_2954	COG1131	(ABC) transporter
BF27_2960	COG2318	DinB family
BF27_2964	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_2965	COG1309	transcriptional regulator
BF27_2966	COG1024	Enoyl-CoA hydratase
BF27_2967	COG2086	electron transfer activity
BF27_2968	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF27_2969	COG3118	belongs to the thioredoxin family
BF27_2971	COG1719	4-vinyl reductase, 4VR
BF27_2972	COG2009	succinate dehydrogenase
BF27_2973	COG1053	succinate dehydrogenase
BF27_2974	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF27_2975	COG0824	Thioesterase
BF27_2976	COG1876	peptidase activity
BF27_2977	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF27_2978	COG1360	Flagellar Motor Protein
BF27_2979	COG1360	Flagellar Motor Protein
BF27_2980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF27_2981	COG4152	abc transporter atp-binding protein
BF27_2982	COG1668	transmembrane transport
BF27_2983	COG1959	2 iron, 2 sulfur cluster binding
BF27_2985	COG0697	spore germination
BF27_2986	COG1396	sequence-specific DNA binding
BF27_2987	COG1983	PspC domain protein
BF27_2989	COG3279	Response regulator of the LytR AlgR family
BF27_2990	COG3275	phosphorelay sensor kinase activity
BF27_2991	COG4608	Belongs to the ABC transporter superfamily
BF27_2992	COG0444	Belongs to the ABC transporter superfamily
BF27_2996	COG0402	S-adenosylhomocysteine deaminase activity
BF27_2997	COG0402	S-adenosylhomocysteine deaminase activity
BF27_2999	COG2233	PERMEase
BF27_30	COG2843	Capsule synthesis protein
BF27_3000	COG2197	response regulator
BF27_3003	COG1309	transcriptional regulator
BF27_3007	COG5401	PFAM Sporulation and spore germination
BF27_3009	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF27_3010	COG0622	Phosphoesterase
BF27_3020	COG0470	DNA polymerase III
BF27_3020	COG1067	ATP-dependent peptidase activity
BF27_3023	COG1764	response to oxidative stress
BF27_3024	COG1846	Transcriptional regulator
BF27_3026	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF27_3028	COG1587	Uroporphyrinogen-III synthase
BF27_3029	COG0113	porphobilinogen synthase activity
BF27_3031	COG1388	LysM domain
BF27_3033	COG0525	valine-tRNA ligase activity
BF27_3034	COG0285	dihydrofolate synthase activity
BF27_3038	COG1077	Cell shape determining protein MreB Mrl
BF27_3039	COG1792	Involved in formation and maintenance of cell shape
BF27_3042	COG2894	cell division
BF27_3043	COG0739	heme binding
BF27_3044	COG1994	Peptidase M50
BF27_3045	COG1530	ribonuclease E activity
BF27_3047	COG2868	ribosomal protein
BF27_3049	COG3290	protein histidine kinase activity
BF27_305	COG1396	sequence-specific DNA binding
BF27_305	COG3800	Transcriptional regulator
BF27_3051	COG0745	RESPONSE REGULATOR receiver
BF27_3053	COG5002	protein histidine kinase activity
BF27_3054	COG1136	(ABC) transporter
BF27_3055	COG0577	efflux transmembrane transporter activity
BF27_3056	COG0577	efflux transmembrane transporter activity
BF27_3057	COG0077	Prephenate dehydratase
BF27_3058	COG2258	MOSC domain
BF27_3059	COG1827	regulation of RNA biosynthetic process
BF27_3060	COG1104	cysteine desulfurase activity
BF27_3061	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF27_3062	COG0157	Belongs to the NadC ModD family
BF27_3067	COG0640	Transcriptional regulator
BF27_3068	COG0697	spore germination
BF27_3069	COG0697	spore germination
BF27_3071	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF27_3077	COG1862	Preprotein translocase
BF27_3079	COG2323	membrane
BF27_3080	COG2244	polysaccharide biosynthetic process
BF27_3082	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF27_3082	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF27_3083	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF27_3084	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF27_3084	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF27_3086	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF27_3089	COG0124	histidyl-tRNA synthetase
BF27_3091	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF27_3093	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF27_3094	COG1959	2 iron, 2 sulfur cluster binding
BF27_3095	COG1104	cysteine desulfurase activity
BF27_3098	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF27_3102	COG0628	permease
BF27_3104	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF27_3108	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF27_3114	COG0768	penicillin binding
BF27_3119	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF27_3120	COG0626	cystathionine gamma-synthase activity
BF27_3121	COG1454	alcohol dehydrogenase
BF27_3121	COG1012	belongs to the aldehyde dehydrogenase family
BF27_3123	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_3131	COG2259	Doxx family
BF27_3132	COG2514	catechol 2,3-dioxygenase activity
BF27_3134	COG3186	Phenylalanine-4-hydroxylase
BF27_3135	COG1404	Belongs to the peptidase S8 family
BF27_3142	COG2267	carboxylic ester hydrolase activity
BF27_3144	COG1785	Belongs to the alkaline phosphatase family
BF27_3147	COG2357	RelA SpoT domain protein
BF27_3149	COG0778	Nitroreductase
BF27_3151	COG1595	DNA-templated transcription, initiation
BF27_3153	COG1191	sigma factor activity
BF27_3155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF27_3156	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF27_3158	COG1534	Rna-binding protein
BF27_3160	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF27_3161	COG0799	negative regulation of ribosome biogenesis
BF27_3162	COG2226	methyltransferase
BF27_3163	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF27_3164	COG1555	photosystem II stabilization
BF27_3164	COG1596	polysaccharide export
BF27_3165	COG2131	deaminase
BF27_3166	COG0658	competence protein
BF27_3166	COG2333	competence protein COMEC
BF27_3168	COG1466	dna polymerase III delta subunit
BF27_3173	COG1733	regulation of RNA biosynthetic process
BF27_3174	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF27_3176	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF27_3180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF27_3181	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF27_3183	COG1610	YqeY-like protein
BF27_3186	COG1702	phosphate starvation-inducible protein PhoH
BF27_3187	COG1480	7TM receptor with intracellular HD hydrolase
BF27_3189	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF27_3190	COG0295	cytidine deaminase activity
BF27_3191	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF27_3194	COG0517	IMP dehydrogenase activity
BF27_3196	COG0358	DNA primase activity
BF27_3197	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF27_3198	COG2010	Cytochrome c
BF27_3199	COG2384	SAM-dependent methyltransferase
BF27_32	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF27_320	COG4824	toxin secretion phage lysis holin
BF27_3200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF27_3206	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_3207	COG1121	(ABC) transporter
BF27_3208	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF27_3209	COG0735	belongs to the Fur family
BF27_3214	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF27_3215	COG0477	Major facilitator Superfamily
BF27_3217	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF27_3218	COG0573	inorganic phosphate transmembrane transporter activity
BF27_3219	COG0581	inorganic phosphate transmembrane transporter activity
BF27_3220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF27_3221	COG0704	Plays a role in the regulation of phosphate uptake
BF27_3222	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF27_3224	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF27_3225	COG4483	Protein conserved in bacteria
BF27_3229	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_3233	COG0626	cystathionine gamma-synthase activity
BF27_3234	COG0626	cystathionine gamma-synthase activity
BF27_3235	COG0646	methionine synthase
BF27_3235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF27_3236	COG1410	methionine synthase
BF27_3236	COG0646	methionine synthase
BF27_3237	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF27_3247	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF27_3248	COG1459	type II secretion system
BF27_3250	COG4970	Tfp pilus assembly protein FimT
BF27_3261	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF27_3267	COG1725	Transcriptional regulator
BF27_3268	COG1131	(ABC) transporter
BF27_3275	COG2076	Multidrug Resistance protein
BF27_3276	COG2076	Multidrug Resistance protein
BF27_3278	COG1609	Transcriptional regulator
BF27_3279	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_3280	COG0095	Lipoate-protein ligase
BF27_3285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF27_3286	COG3872	metal-dependent enzyme
BF27_3289	COG0006	proline dipeptidase activity
BF27_3294	COG3854	ATPases associated with a variety of cellular activities
BF27_3303	COG0511	ligase activity, forming carbon-carbon bonds
BF27_3304	COG0439	Biotin carboxylase
BF27_3305	COG1302	Protein conserved in bacteria
BF27_3310	COG0142	geranyltranstransferase activity
BF27_3312	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF27_3314	COG0497	DNA recombination
BF27_3315	COG0750	zinc metalloprotease
BF27_3316	COG0745	RESPONSE REGULATOR receiver
BF27_3318	COG3093	addiction module antidote protein HigA
BF27_3319	COG0584	glycerophosphoryl diester phosphodiesterase
BF27_3321	COG3290	protein histidine kinase activity
BF27_3321	COG3829	transcription factor binding
BF27_3322	COG0280	phosphate acetyltransferase
BF27_3323	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF27_3325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF27_3326	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF27_3327	COG0022	dehydrogenase e1 component
BF27_3328	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF27_3329	COG0772	Belongs to the SEDS family
BF27_3330	COG2816	NAD+ diphosphatase activity
BF27_3333	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF27_3334	COG0765	amino acid transport
BF27_3335	COG1126	abc transporter atp-binding protein
BF27_3336	COG4129	membrane
BF27_3337	COG1376	ErfK ybiS ycfS ynhG family protein
BF27_3339	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_3340	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF27_3342	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF27_3345	COG1760	l-serine dehydratase
BF27_3346	COG1760	l-serine dehydratase
BF27_3347	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF27_3348	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_3349	COG0300	oxidoreductase activity
BF27_335	COG4626	Terminase
BF27_335	COG1802	Transcriptional regulator
BF27_3352	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF27_3354	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF27_3358	COG1522	sequence-specific DNA binding
BF27_3360	COG0737	Belongs to the 5'-nucleotidase family
BF27_3363	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF27_3365	COG0156	8-amino-7-oxononanoate synthase activity
BF27_3366	COG1073	alpha beta
BF27_3366	COG2226	methyltransferase
BF27_3367	COG4106	trans-aconitate 2-methyltransferase activity
BF27_3368	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF27_3372	COG0307	riboflavin synthase, alpha
BF27_3373	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF27_3373	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF27_3376	COG1073	alpha beta
BF27_3377	COG0456	acetyltransferase
BF27_3378	COG1609	Transcriptional regulator
BF27_3379	COG2056	Na+-H+ antiporter family
BF27_3380	COG0596	Alpha beta hydrolase
BF27_3382	COG1525	nuclease
BF27_3382	COG4085	toxin activity
BF27_3382	COG0737	Belongs to the 5'-nucleotidase family
BF27_3384	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF27_3384	COG0456	acetyltransferase
BF27_3385	COG0656	L-ascorbic acid biosynthetic process
BF27_3386	COG0667	Aldo Keto reductase
BF27_3390	COG1300	Membrane
BF27_3391	COG0735	belongs to the Fur family
BF27_3393	COG4974	Belongs to the 'phage' integrase family
BF27_3398	COG0598	Magnesium transport protein CorA
BF27_34	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF27_3401	COG1846	Transcriptional regulator
BF27_3404	COG1131	(ABC) transporter
BF27_3405	COG1725	Transcriptional regulator
BF27_3406	COG1686	Belongs to the peptidase S11 family
BF27_3410	COG0733	neurotransmitter:sodium symporter activity
BF27_3415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_3418	COG0697	spore germination
BF27_3419	COG0561	phosphatase activity
BF27_3420	COG4086	secreted protein
BF27_3421	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF27_3422	COG0456	acetyltransferase
BF27_3423	COG1547	Domain of unknown function (DUF309)
BF27_3428	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF27_3432	COG3711	transcriptional antiterminator
BF27_3433	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF27_3433	COG1263	PTS System
BF27_3433	COG2190	(PTS) system
BF27_3438	COG0778	Nitroreductase
BF27_3439	COG3706	GGDEF domain
BF27_3448	COG0436	Aminotransferase
BF27_3449	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF27_3453	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_3454	COG1695	Transcriptional regulator
BF27_3461	COG0183	Belongs to the thiolase family
BF27_3469	COG3842	ATPase activity
BF27_3470	COG0366	Alpha amylase catalytic
BF27_3472	COG2182	Extracellular solute-binding protein
BF27_3473	COG1175	transmembrane transport
BF27_3474	COG3833	ABC-type maltose transport systems, permease component
BF27_3475	COG1609	Transcriptional regulator
BF27_3476	COG0436	Aminotransferase
BF27_3478	COG2205	protein histidine kinase activity
BF27_3480	COG3209	COG3209 Rhs family protein
BF27_3484	COG2814	Major facilitator Superfamily
BF27_3491	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF27_3493	COG1408	metallophosphoesterase
BF27_3494	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_3495	COG2200	EAL domain
BF27_3498	COG4703	Protein of unknown function (DUF1797)
BF27_35	COG0440	acetolactate synthase activity
BF27_3500	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF27_3502	COG0517	IMP dehydrogenase activity
BF27_3503	COG0583	DNA-binding transcription factor activity
BF27_3507	COG0569	domain protein
BF27_3508	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF27_351	COG0662	Cupin 2, conserved barrel domain protein
BF27_3510	COG0561	phosphatase activity
BF27_3511	COG0242	peptide deformylase activity
BF27_3513	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF27_3514	COG0022	dehydrogenase e1 component
BF27_3524	COG1982	Orn Lys Arg decarboxylase major
BF27_3528	COG0483	inositol monophosphate 1-phosphatase activity
BF27_3533	COG4896	Protein conserved in bacteria
BF27_3535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF27_3536	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF27_3537	COG4838	Belongs to the UPF0358 family
BF27_3538	COG0772	Belongs to the SEDS family
BF27_3539	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF27_3546	COG3336	cytochrome c oxidase
BF27_3549	COG2340	Cysteine-rich secretory protein family
BF27_3552	COG0406	alpha-ribazole phosphatase activity
BF27_3557	COG0742	ribosomal rna small subunit methyltransferase
BF27_3558	COG3314	Sporulation integral membrane protein YlbJ
BF27_3560	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF27_3561	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF27_3563	COG0582	viral genome integration into host DNA
BF27_3567	COG1396	sequence-specific DNA binding
BF27_3570	COG1396	sequence-specific DNA binding
BF27_3576	COG1484	DNA-dependent DNA replication
BF27_3581	COG1191	sigma factor activity
BF27_3596	COG0582	viral genome integration into host DNA
BF27_36	COG0028	Belongs to the TPP enzyme family
BF27_3601	COG1802	Transcriptional regulator
BF27_3601	COG4626	Terminase
BF27_3618	COG4824	toxin secretion phage lysis holin
BF27_3628	COG1399	metal-binding, possibly nucleic acid-binding protein
BF27_3632	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF27_3635	COG4839	cell division protein FtsL
BF27_3637	COG0768	penicillin binding
BF27_3638	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF27_364	COG3800	Transcriptional regulator
BF27_364	COG1396	sequence-specific DNA binding
BF27_3641	COG0772	Belongs to the SEDS family
BF27_3642	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF27_3643	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF27_3644	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF27_3645	COG0849	cell division
BF27_3646	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF27_3648	COG1191	sigma factor activity
BF27_3649	COG1191	sigma factor activity
BF27_3650	COG1873	PFAM PRC-barrel domain
BF27_3652	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF27_3654	COG0762	integral membrane protein
BF27_3655	COG2302	S4 RNA-binding domain
BF27_3656	COG3599	regulation of cell shape
BF27_3657	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF27_3660	COG0564	pseudouridine synthase activity
BF27_3665	COG0505	Belongs to the CarA family
BF27_3673	COG3069	C4-dicarboxylate transmembrane transporter activity
BF27_3676	COG0006	proline dipeptidase activity
BF27_3678	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF27_3679	COG1561	YicC-like family, N-terminal region
BF27_3681	COG0194	GDP metabolic process
BF27_3683	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF27_3684	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF27_3685	COG0242	peptide deformylase activity
BF27_3687	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF27_3687	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF27_3689	COG0631	protein serine/threonine phosphatase activity
BF27_369	COG0438	transferase activity, transferring glycosyl groups
BF27_3690	COG2815	serine threonine protein kinase
BF27_3690	COG0515	serine threonine protein kinase
BF27_3691	COG1162	GTPase activity
BF27_3692	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF27_3693	COG1564	THIamine pyrophosphokinase
BF27_3695	COG1302	Protein conserved in bacteria
BF27_3696	COG1461	Dihydroxyacetone kinase
BF27_3697	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF27_37	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF27_370	COG1215	transferase activity, transferring glycosyl groups
BF27_3700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF27_3701	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_3704	COG1196	nuclear chromosome segregation
BF27_3705	COG0552	protein localization to endoplasmic reticulum
BF27_3707	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF27_3709	COG1837	Belongs to the UPF0109 family
BF27_3717	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF27_3718	COG0758	DNA mediated transformation
BF27_3719	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF27_3721	COG4974	Belongs to the 'phage' integrase family
BF27_3727	COG0528	UMP kinase activity
BF27_373	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF27_3730	COG4589	Belongs to the CDS family
BF27_3731	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF27_3732	COG0750	zinc metalloprotease
BF27_3736	COG0195	Participates in both transcription termination and antitermination
BF27_3737	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF27_3738	COG1358	cellular component organization or biogenesis
BF27_3740	COG1550	Protein conserved in bacteria
BF27_3742	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF27_3743	COG0196	riboflavin kinase activity
BF27_3746	COG0726	polysaccharide deacetylase
BF27_3747	COG0612	Peptidase, M16
BF27_3748	COG1873	PFAM PRC-barrel domain
BF27_3749	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF27_3750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF27_3751	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF27_3752	COG0527	aspartate kinase activity
BF27_3754	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF27_3755	COG0740	serine-type endopeptidase activity
BF27_3757	COG1674	ftsk spoiiie
BF27_3758	COG2188	Transcriptional regulator
BF27_3764	COG0612	Peptidase, M16
BF27_3765	COG0612	Peptidase, M16
BF27_3766	COG0300	oxidoreductase activity
BF27_3769	COG1426	Protein conserved in bacteria
BF27_377	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF27_3770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF27_3775	COG1692	metallophosphoesterase
BF27_3776	COG2359	stage V sporulation protein S
BF27_3778	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF27_3778	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF27_3779	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF27_3780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF27_3781	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF27_3790	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF27_3792	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF27_3793	COG1368	sulfuric ester hydrolase activity
BF27_3794	COG0562	UDP-galactopyranose mutase
BF27_3795	COG3773	Cell wall hydrolase
BF27_3796	COG1404	Belongs to the peptidase S8 family
BF27_3799	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF27_380	COG0754	glutathionylspermidine amidase activity
BF27_3800	COG0596	Alpha beta hydrolase
BF27_3800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF27_3801	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_3802	COG1380	Effector of murein hydrolase LrgA
BF27_3803	COG1346	cytolysis
BF27_3806	COG5001	Diguanylate cyclase
BF27_3806	COG3300	MHYT domain
BF27_3807	COG0346	lactoylglutathione lyase activity
BF27_3808	COG2267	carboxylic ester hydrolase activity
BF27_3811	COG2364	Membrane
BF27_3813	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF27_3814	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF27_3815	COG2169	Transcriptional regulator
BF27_3816	COG0708	Exodeoxyribonuclease III
BF27_3818	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_3819	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_3820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_3821	COG1120	ATPase activity
BF27_3822	COG2819	hydrolase of the alpha beta superfamily
BF27_3824	COG1937	Protein conserved in bacteria
BF27_3825	COG2608	mercury ion transmembrane transporter activity
BF27_3826	COG2217	Heavy metal translocating P-type atpase
BF27_3828	COG2116	formate transmembrane transporter activity
BF27_3829	COG1408	metallophosphoesterase
BF27_3832	COG1113	amino acid transport
BF27_3835	COG2322	membrane
BF27_3836	COG1979	alcohol dehydrogenase
BF27_3837	COG1979	alcohol dehydrogenase
BF27_3838	COG1349	DNA-binding transcription factor activity
BF27_3839	COG1105	Belongs to the carbohydrate kinase PfkB family
BF27_3842	COG3584	3D domain protein
BF27_3842	COG1388	LysM domain
BF27_3848	COG0464	growth
BF27_385	COG0456	acetyltransferase
BF27_3850	COG2860	membrane
BF27_3851	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF27_3852	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF27_3853	COG0789	Transcriptional regulator
BF27_3854	COG0174	glutamine synthetase
BF27_3858	COG1396	sequence-specific DNA binding
BF27_387	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF27_3874	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF27_3882	COG1595	DNA-templated transcription, initiation
BF27_389	COG2311	Membrane
BF27_39	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF27_390	COG2233	PERMEase
BF27_3912	COG4824	toxin secretion phage lysis holin
BF27_3913	COG3409	Peptidoglycan-binding domain 1 protein
BF27_3913	COG1388	LysM domain
BF27_3913	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF27_392	COG0024	Methionine aminopeptidase
BF27_3921	COG1695	Transcriptional regulator
BF27_3925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF27_3927	COG0737	Belongs to the 5'-nucleotidase family
BF27_393	COG3173	Aminoglycoside phosphotransferase
BF27_3930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF27_3931	COG3639	organic phosphonate transmembrane transporter activity
BF27_3937	COG1132	(ABC) transporter
BF27_3938	COG1132	(ABC) transporter
BF27_3941	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF27_3941	COG3409	Peptidoglycan-binding domain 1 protein
BF27_3943	COG0730	response to heat
BF27_3946	COG1346	cytolysis
BF27_3948	COG0583	DNA-binding transcription factor activity
BF27_395	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF27_3950	COG1131	(ABC) transporter
BF27_3954	COG0785	Cytochrome C biogenesis protein
BF27_3955	COG4846	Membrane protein involved in cytochrome C biogenesis
BF27_396	COG1199	ATP-dependent helicase activity
BF27_3962	COG2226	methyltransferase
BF27_3967	COG0010	Belongs to the arginase family
BF27_3968	COG1329	Transcriptional regulator
BF27_3969	COG1902	pentaerythritol trinitrate reductase activity
BF27_3970	COG0069	glutamate synthase activity
BF27_3971	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF27_3972	COG0346	lactoylglutathione lyase activity
BF27_3973	COG0400	carboxylic ester hydrolase activity
BF27_3974	COG5002	protein histidine kinase activity
BF27_3976	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_398	COG0116	Belongs to the methyltransferase superfamily
BF27_3985	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_3986	COG1268	BioY protein
BF27_3987	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_3988	COG0183	Belongs to the thiolase family
BF27_3991	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF27_3993	COG2211	Major facilitator Superfamily
BF27_3997	COG0726	polysaccharide deacetylase
BF27_3999	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF27_4	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF27_4000	COG2274	protein secretion by the type I secretion system
BF27_4002	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF27_4008	COG0824	Thioesterase
BF27_4009	COG4841	protein insertion into membrane
BF27_4010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF27_4013	COG0745	RESPONSE REGULATOR receiver
BF27_4014	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF27_4015	COG1832	CoA-binding protein
BF27_4016	COG0187	DNA topoisomerase II activity
BF27_4017	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF27_4018	COG0673	inositol 2-dehydrogenase activity
BF27_4020	COG1131	(ABC) transporter
BF27_4023	COG1595	DNA-templated transcription, initiation
BF27_4025	COG1316	TRANSCRIPTIONal
BF27_4026	COG1301	dicarboxylic acid transport
BF27_4027	COG4166	transmembrane transport
BF27_4028	COG4166	transmembrane transport
BF27_4029	COG4166	transmembrane transport
BF27_4030	COG2226	methyltransferase
BF27_4038	COG0697	spore germination
BF27_4040	COG3383	formate dehydrogenase (NAD+) activity
BF27_4041	COG2427	Protein of unknown function (DUF1641)
BF27_4042	COG5609	conserved protein (DUF2294)
BF27_4043	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF27_4045	COG2116	formate transmembrane transporter activity
BF27_4046	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF27_4047	COG0303	'Molybdopterin
BF27_4048	COG0314	molybdopterin synthase activity
BF27_4050	COG0489	protein tyrosine kinase activity
BF27_4053	COG3326	Membrane
BF27_4054	COG2962	Rard protein
BF27_4055	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF27_4056	COG1657	PFAM Prenyltransferase squalene oxidase
BF27_4058	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4059	COG1012	belongs to the aldehyde dehydrogenase family
BF27_4061	COG4145	pantothenate transmembrane transporter activity
BF27_4064	COG0165	Argininosuccinate lyase
BF27_4066	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4074	COG0716	FMN binding
BF27_4076	COG1278	Cold shock
BF27_4082	COG2720	vancomycin resistance protein
BF27_4083	COG2514	catechol 2,3-dioxygenase activity
BF27_4085	COG1285	pathogenesis
BF27_4087	COG1024	Enoyl-CoA hydratase
BF27_4088	COG1216	Glycosyl transferase, family 2
BF27_409	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF27_409	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF27_4094	COG0277	FAD linked oxidase domain protein
BF27_4095	COG0385	Bile acid
BF27_4097	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF27_4098	COG2808	Putative FMN-binding domain
BF27_4100	COG0457	Tetratricopeptide repeat
BF27_4102	COG0604	alcohol dehydrogenase
BF27_4103	COG0640	Transcriptional regulator
BF27_4107	COG0584	glycerophosphoryl diester phosphodiesterase
BF27_411	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF27_4113	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF27_4114	COG1164	Oligoendopeptidase f
BF27_4115	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF27_4118	COG1193	negative regulation of DNA recombination
BF27_412	COG3935	DnaD domain protein
BF27_4122	COG0583	DNA-binding transcription factor activity
BF27_4128	COG0384	phenazine biosynthesis protein PhzF
BF27_4129	COG3739	integral membrane protein
BF27_4130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_4131	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF27_4132	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_4136	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF27_4137	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF27_4143	COG2814	Major facilitator Superfamily
BF27_4144	COG1113	amino acid transport
BF27_4145	COG0604	alcohol dehydrogenase
BF27_4152	COG2072	flavoprotein involved in K transport
BF27_4159	COG3757	hydrolase, family 25
BF27_4159	COG3409	Peptidoglycan-binding domain 1 protein
BF27_416	COG1199	ATP-dependent helicase activity
BF27_416	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF27_4160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_4163	COG1151	hydroxylamine reductase activity
BF27_4168	COG3152	Membrane
BF27_4172	COG1309	transcriptional regulator
BF27_4175	COG1191	sigma factor activity
BF27_4178	COG0726	polysaccharide deacetylase
BF27_4182	COG1733	regulation of RNA biosynthetic process
BF27_4183	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF27_4188	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4190	COG0384	phenazine biosynthesis protein PhzF
BF27_4194	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_4197	COG1733	regulation of RNA biosynthetic process
BF27_4198	COG1733	regulation of RNA biosynthetic process
BF27_4199	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF27_4200	COG0673	inositol 2-dehydrogenase activity
BF27_4201	COG2188	Transcriptional regulator
BF27_4202	COG1733	regulation of RNA biosynthetic process
BF27_4203	COG1393	Belongs to the ArsC family
BF27_4208	COG0814	amino acid
BF27_4209	COG0346	lactoylglutathione lyase activity
BF27_4212	COG2814	Major facilitator Superfamily
BF27_4213	COG0656	L-ascorbic acid biosynthetic process
BF27_4218	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4221	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF27_4222	COG0604	alcohol dehydrogenase
BF27_4223	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF27_4224	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF27_4226	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF27_4227	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF27_4229	COG1070	Carbohydrate kinase
BF27_423	COG0438	transferase activity, transferring glycosyl groups
BF27_4230	COG2706	6-phosphogluconolactonase activity
BF27_4231	COG3813	Protein conserved in bacteria
BF27_4232	COG1357	PFAM Pentapeptide repeats (8 copies)
BF27_4233	COG0697	spore germination
BF27_4234	COG0789	Transcriptional regulator
BF27_4235	COG1253	flavin adenine dinucleotide binding
BF27_424	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF27_4241	COG0477	Major facilitator Superfamily
BF27_4243	COG2226	methyltransferase
BF27_4247	COG0628	permease
BF27_4249	COG0180	Tryptophanyl-tRNA synthetase
BF27_4251	COG1136	(ABC) transporter
BF27_4253	COG0110	maltose O-acetyltransferase activity
BF27_4254	COG0738	Major facilitator superfamily
BF27_4255	COG1940	carbohydrate kinase activity
BF27_4256	COG0346	lactoylglutathione lyase activity
BF27_4263	COG1011	Hydrolase
BF27_4268	COG1131	(ABC) transporter
BF27_427	COG1694	Mazg nucleotide pyrophosphohydrolase
BF27_4270	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4274	COG0778	Nitroreductase
BF27_4275	COG1733	regulation of RNA biosynthetic process
BF27_4278	COG0124	histidyl-tRNA synthetase
BF27_4279	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF27_428	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_4280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF27_4281	COG3620	sequence-specific DNA binding
BF27_4284	COG2356	endonuclease I
BF27_4285	COG1288	antiporter activity
BF27_4286	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF27_4289	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF27_4290	COG1122	ATPase activity
BF27_4296	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF27_4298	COG2031	fatty acid transporter
BF27_43	COG2084	Dehydrogenase
BF27_430	COG2738	Putative neutral zinc metallopeptidase
BF27_4300	COG1309	transcriptional regulator
BF27_4301	COG2076	Multidrug Resistance protein
BF27_4307	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF27_4310	COG2814	Major facilitator Superfamily
BF27_4311	COG1846	Transcriptional regulator
BF27_4313	COG0477	Major facilitator Superfamily
BF27_4320	COG3409	Peptidoglycan-binding domain 1 protein
BF27_4320	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF27_4323	COG2207	Transcriptional regulator
BF27_4323	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_4324	COG0662	Cupin 2, conserved barrel domain protein
BF27_4327	COG1595	DNA-templated transcription, initiation
BF27_433	COG4347	Protein of unknown function (DUF1405)
BF27_4331	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF27_4334	COG0531	amino acid
BF27_4335	COG1522	sequence-specific DNA binding
BF27_4336	COG1335	isochorismatase
BF27_4338	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF27_4339	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF27_4340	COG1760	l-serine dehydratase
BF27_4341	COG1760	l-serine dehydratase
BF27_4342	COG0814	amino acid
BF27_4345	COG1309	transcriptional regulator
BF27_4346	COG2814	Major facilitator Superfamily
BF27_4347	COG2184	nucleotidyltransferase activity
BF27_435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF27_4350	COG0534	Mate efflux family protein
BF27_4357	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF27_4361	COG0457	Tetratricopeptide repeat
BF27_4362	COG1609	Transcriptional regulator
BF27_4363	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF27_4364	COG0561	phosphatase activity
BF27_4365	COG0673	inositol 2-dehydrogenase activity
BF27_4366	COG0738	Major facilitator superfamily
BF27_4370	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF27_4372	COG0583	DNA-binding transcription factor activity
BF27_4374	COG1139	Iron-sulfur cluster binding protein
BF27_4375	COG1556	Lactate utilization protein
BF27_4376	COG2271	Major facilitator Superfamily
BF27_4377	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_4378	COG2808	Putative FMN-binding domain
BF27_4379	COG0456	acetyltransferase
BF27_4380	COG1846	Transcriptional regulator
BF27_4381	COG2364	Membrane
BF27_4383	COG3850	Histidine kinase
BF27_4383	COG5002	protein histidine kinase activity
BF27_4386	COG0577	efflux transmembrane transporter activity
BF27_4387	COG1136	(ABC) transporter
BF27_439	COG0457	Tetratricopeptide repeat
BF27_4390	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF27_4391	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_4393	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF27_4394	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_4397	COG1476	TRANSCRIPTIONal
BF27_440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF27_4402	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF27_4407	COG3850	Histidine kinase
BF27_4407	COG5002	protein histidine kinase activity
BF27_4408	COG0745	RESPONSE REGULATOR receiver
BF27_4413	COG2814	Major facilitator Superfamily
BF27_4420	COG2169	Transcriptional regulator
BF27_4424	COG0346	lactoylglutathione lyase activity
BF27_4427	COG1522	sequence-specific DNA binding
BF27_443	COG0105	UTP biosynthetic process
BF27_4430	COG0443	Heat shock 70 kDa protein
BF27_4434	COG0640	Transcriptional regulator
BF27_4435	COG0346	lactoylglutathione lyase activity
BF27_4436	COG0798	PFAM Bile acid sodium symporter
BF27_444	COG0142	geranyltranstransferase activity
BF27_4442	COG1121	(ABC) transporter
BF27_4443	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF27_4444	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF27_4445	COG2267	carboxylic ester hydrolase activity
BF27_4446	COG1575	Belongs to the MenA family. Type 1 subfamily
BF27_4448	COG5609	conserved protein (DUF2294)
BF27_4449	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF27_4451	COG0288	reversible hydration of carbon dioxide
BF27_4452	COG0415	Belongs to the DNA photolyase family
BF27_4459	COG0598	Magnesium transport protein CorA
BF27_446	COG0142	geranyltranstransferase activity
BF27_4460	COG1846	Transcriptional regulator
BF27_4461	COG0583	DNA-binding transcription factor activity
BF27_4465	COG1335	isochorismatase
BF27_4466	COG2267	carboxylic ester hydrolase activity
BF27_4467	COG0753	catalase activity
BF27_4468	COG0737	Belongs to the 5'-nucleotidase family
BF27_4474	COG1115	amino acid carrier protein
BF27_4476	COG2066	Belongs to the glutaminase family
BF27_4477	COG4191	Histidine kinase
BF27_4478	COG0784	Response regulator, receiver
BF27_4479	COG0697	spore germination
BF27_4480	COG0531	amino acid
BF27_4483	COG0281	malic enzyme
BF27_4485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF27_4486	COG1114	Component of the transport system for branched-chain amino acids
BF27_4489	COG0322	excinuclease ABC activity
BF27_449	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF27_4491	COG1396	sequence-specific DNA binding
BF27_4492	COG0252	asparaginase activity
BF27_4493	COG1027	Aspartate ammonia-lyase
BF27_4496	COG1063	alcohol dehydrogenase
BF27_4502	COG1113	amino acid transport
BF27_4503	COG1113	amino acid transport
BF27_4504	COG1280	lysine exporter protein (LysE YggA)
BF27_4505	COG3403	YqcI/YcgG family
BF27_4507	COG5577	PFAM Coat F domain
BF27_4510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_4511	COG3848	Pyruvate phosphate dikinase
BF27_4511	COG0574	Belongs to the PEP-utilizing enzyme family
BF27_4514	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF27_4521	COG1960	acyl-CoA dehydrogenase activity
BF27_4523	COG0640	Transcriptional regulator
BF27_4524	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF27_4527	COG1414	Transcriptional regulator
BF27_4528	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF27_4529	COG1984	allophanate hydrolase subunit 2
BF27_4535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF27_4537	COG0768	penicillin binding
BF27_4546	COG4335	DNA alkylation repair
BF27_4548	COG0833	amino acid
BF27_4550	COG0730	response to heat
BF27_4556	COG0596	Alpha beta hydrolase
BF27_4557	COG0745	RESPONSE REGULATOR receiver
BF27_4558	COG0642	Histidine kinase
BF27_4562	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_4566	COG0456	acetyltransferase
BF27_4567	COG2207	Transcriptional regulator
BF27_4572	COG0577	efflux transmembrane transporter activity
BF27_4572	COG1136	(ABC) transporter
BF27_4574	COG1725	Transcriptional regulator
BF27_4581	COG1846	Transcriptional regulator
BF27_4582	COG0778	Nitroreductase
BF27_4584	COG0714	Associated with various cellular activities
BF27_4590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF27_4592	COG0753	catalase activity
BF27_4593	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF27_4595	COG0463	Glycosyl transferase, family 2
BF27_4599	COG0463	Glycosyl transferase, family 2
BF27_46	COG2323	membrane
BF27_4604	COG0714	Associated with various cellular activities
BF27_4608	COG0346	lactoylglutathione lyase activity
BF27_4609	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_4611	COG3279	Response regulator of the LytR AlgR family
BF27_4613	COG4377	Putative membrane peptidase family (DUF2324)
BF27_4616	COG3655	Transcriptional regulator
BF27_4618	COG1785	Belongs to the alkaline phosphatase family
BF27_4619	COG3239	Fatty acid desaturase
BF27_4620	COG1690	Belongs to the RtcB family
BF27_4621	COG0833	amino acid
BF27_4622	COG1414	Transcriptional regulator
BF27_4623	COG4187	Peptidase family M20/M25/M40
BF27_4624	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF27_4625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF27_4627	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_463	COG0252	asparaginase activity
BF27_4631	COG2329	Antibiotic biosynthesis monooxygenase
BF27_4637	COG1070	Carbohydrate kinase
BF27_4638	COG2390	Transcriptional regulator
BF27_464	COG0492	ferredoxin-NADP+ reductase activity
BF27_4640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF27_4642	COG1879	ABC-type sugar transport system periplasmic component
BF27_4648	COG1595	DNA-templated transcription, initiation
BF27_4650	COG1388	LysM domain
BF27_4650	COG3584	3D domain protein
BF27_4657	COG1605	Chorismate mutase
BF27_4657	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF27_4658	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF27_4659	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF27_4660	COG0287	Prephenate dehydrogenase
BF27_4664	COG1309	transcriptional regulator
BF27_4665	COG1033	growth of symbiont in host cell
BF27_4665	COG2409	Drug exporters of the RND superfamily
BF27_4667	COG0488	(ABC) transporter
BF27_4668	COG1368	sulfuric ester hydrolase activity
BF27_4669	COG0861	Integral membrane protein TerC family
BF27_4671	COG0726	polysaccharide deacetylase
BF27_4673	COG4912	Dna alkylation repair
BF27_4677	COG2318	DinB family
BF27_4678	COG0697	spore germination
BF27_468	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF27_4683	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF27_469	COG4862	establishment of competence for transformation
BF27_4691	COG1116	anion transmembrane transporter activity
BF27_4692	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF27_4693	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF27_4694	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF27_4696	COG0628	permease
BF27_47	COG5566	PFAM Mor transcription activator
BF27_4704	COG1131	(ABC) transporter
BF27_4708	COG5146	pantothenate kinase activity
BF27_4709	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF27_471	COG1408	metallophosphoesterase
BF27_4710	COG0436	Aminotransferase
BF27_4717	COG2226	methyltransferase
BF27_4720	COG2261	transglycosylase associated protein
BF27_4724	COG0477	Major facilitator Superfamily
BF27_4724	COG2814	Major facilitator Superfamily
BF27_4725	COG4533	DNA binding
BF27_4726	COG0789	Transcriptional regulator
BF27_4727	COG1664	Polymer-forming cytoskeletal
BF27_4729	COG2814	Major facilitator Superfamily
BF27_473	COG1266	CAAX protease self-immunity
BF27_4733	COG1307	EDD domain protein, DegV family
BF27_4735	COG1164	Oligoendopeptidase f
BF27_474	COG0514	ATP-dependent DNA helicase (RecQ)
BF27_4742	COG0745	RESPONSE REGULATOR receiver
BF27_4743	COG5002	protein histidine kinase activity
BF27_4744	COG2936	dipeptidyl-peptidase activity
BF27_4751	COG4948	Mandelate Racemase Muconate Lactonizing
BF27_4753	COG4166	transmembrane transport
BF27_4754	COG0519	Catalyzes the synthesis of GMP from XMP
BF27_4755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF27_4758	COG0586	Pfam SNARE associated Golgi protein
BF27_476	COG1141	Ferredoxin
BF27_4766	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF27_4767	COG3938	Belongs to the proline racemase family
BF27_4769	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF27_477	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF27_4770	COG1012	belongs to the aldehyde dehydrogenase family
BF27_4771	COG1115	amino acid carrier protein
BF27_4772	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF27_4774	COG3397	chitin binding
BF27_4779	COG4637	Psort location Cytoplasmic, score
BF27_4783	COG0514	ATP-dependent DNA helicase (RecQ)
BF27_4784	COG2105	PFAM AIG2 family protein
BF27_4787	COG3973	AAA domain
BF27_4798	COG0658	competence protein
BF27_4798	COG2333	competence protein COMEC
BF27_480	COG2096	Adenosyltransferase
BF27_4803	COG2205	protein histidine kinase activity
BF27_4807	COG3397	chitin binding
BF27_4808	COG2153	protein acetylation
BF27_4809	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF27_481	COG5002	protein histidine kinase activity
BF27_4812	COG0740	serine-type endopeptidase activity
BF27_4814	COG0517	IMP dehydrogenase activity
BF27_4814	COG4175	Glycine betaine
BF27_4815	COG4176	ABC-type proline glycine betaine transport system permease component
BF27_482	COG0745	RESPONSE REGULATOR receiver
BF27_4821	COG0456	acetyltransferase
BF27_4821	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF27_4822	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_4824	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF27_4825	COG0022	dehydrogenase e1 component
BF27_4826	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF27_4827	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF27_483	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF27_4831	COG1959	2 iron, 2 sulfur cluster binding
BF27_4836	COG1349	DNA-binding transcription factor activity
BF27_484	COG1333	cytochrome c biogenesis protein
BF27_4840	COG3284	Transcriptional regulator
BF27_4846	COG1309	transcriptional regulator
BF27_4847	COG3844	kynureninase activity
BF27_4848	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF27_4849	COG3483	tryptophan 2,3-dioxygenase activity
BF27_4852	COG3409	Peptidoglycan-binding domain 1 protein
BF27_4852	COG3773	Cell wall hydrolase
BF27_4853	COG2959	enzyme of heme biosynthesis
BF27_4856	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_4857	COG4129	membrane
BF27_486	COG1187	pseudouridine synthase activity
BF27_4863	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_4864	COG0697	spore germination
BF27_4866	COG0201	protein transport
BF27_487	COG0700	Nucleoside recognition
BF27_4870	COG3227	Zinc metalloprotease (Elastase)
BF27_4871	COG1523	belongs to the glycosyl hydrolase 13 family
BF27_4874	COG0076	glutamate decarboxylase activity
BF27_4878	COG1011	Hydrolase
BF27_488	COG2715	membrane protein required for spore maturation
BF27_4883	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF27_489	COG1686	Belongs to the peptidase S11 family
BF27_4891	COG0322	excinuclease ABC activity
BF27_4894	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF27_4899	COG4667	esterase of the alpha-beta hydrolase superfamily
BF27_49	COG0733	neurotransmitter:sodium symporter activity
BF27_490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF27_4905	COG3878	Protein conserved in bacteria
BF27_4912	COG1051	belongs to the nudix hydrolase family
BF27_4913	COG0592	DNA-directed DNA polymerase activity
BF27_4914	COG2816	NAD+ diphosphatase activity
BF27_4916	COG2223	nitrite transmembrane transporter activity
BF27_4923	COG0697	spore germination
BF27_4924	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_4925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_4928	COG0584	glycerophosphoryl diester phosphodiesterase
BF27_493	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF27_493	COG0392	lysyltransferase activity
BF27_4932	COG2814	Major facilitator Superfamily
BF27_4937	COG0693	protein deglycase activity
BF27_4947	COG0604	alcohol dehydrogenase
BF27_4950	COG2205	protein histidine kinase activity
BF27_4953	COG1122	ATPase activity
BF27_4955	COG1794	racemase activity, acting on amino acids and derivatives
BF27_4956	COG1819	glycosyl
BF27_4958	COG5002	protein histidine kinase activity
BF27_4960	COG0561	phosphatase activity
BF27_4967	COG2124	cytochrome p450
BF27_497	COG5002	protein histidine kinase activity
BF27_498	COG0582	viral genome integration into host DNA
BF27_4983	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF27_4985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_4986	COG0460	homoserine dehydrogenase
BF27_4990	COG0577	efflux transmembrane transporter activity
BF27_4991	COG1136	(ABC) transporter
BF27_4996	COG2205	protein histidine kinase activity
BF27_4998	COG0745	RESPONSE REGULATOR receiver
BF27_50	COG2244	polysaccharide biosynthetic process
BF27_500	COG1801	Protein of unknown function DUF72
BF27_5000	COG3773	Cell wall hydrolase
BF27_5003	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF27_5006	COG1063	alcohol dehydrogenase
BF27_5008	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_501	COG3852	Histidine kinase
BF27_5012	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF27_5016	COG2814	Major facilitator Superfamily
BF27_5018	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF27_5021	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF27_5021	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF27_5026	COG3227	Zinc metalloprotease (Elastase)
BF27_5030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF27_5035	COG1686	Belongs to the peptidase S11 family
BF27_5036	COG2318	DinB family
BF27_5038	COG0572	uridine kinase
BF27_5039	COG1247	-acetyltransferase
BF27_504	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF27_5041	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF27_5042	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF27_5043	COG1024	Enoyl-CoA hydratase
BF27_5044	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF27_5045	COG0511	ligase activity, forming carbon-carbon bonds
BF27_5046	COG0439	Biotin carboxylase
BF27_5047	COG1960	acyl-CoA dehydrogenase activity
BF27_505	COG1392	Phosphate transport regulator
BF27_5050	COG1309	transcriptional regulator
BF27_5052	COG1131	(ABC) transporter
BF27_5055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF27_5056	COG1252	NADH dehydrogenase
BF27_5058	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_506	COG0306	phosphate transporter
BF27_5062	COG1309	transcriptional regulator
BF27_5067	COG1876	peptidase activity
BF27_507	COG0730	response to heat
BF27_5070	COG1476	TRANSCRIPTIONal
BF27_5071	COG0457	Tetratricopeptide repeat
BF27_5073	COG0737	Belongs to the 5'-nucleotidase family
BF27_5076	COG3718	enzyme involved in inositol metabolism
BF27_5082	COG0673	inositol 2-dehydrogenase activity
BF27_5083	COG2814	Major facilitator Superfamily
BF27_5084	COG1609	Transcriptional regulator
BF27_5085	COG2367	Beta-lactamase
BF27_5087	COG0768	penicillin binding
BF27_5089	COG1595	DNA-templated transcription, initiation
BF27_5093	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF27_510	COG1017	nitric oxide dioxygenase activity
BF27_510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF27_5101	COG1846	Transcriptional regulator
BF27_5102	COG3961	Belongs to the TPP enzyme family
BF27_5103	COG2226	methyltransferase
BF27_5105	COG0500	methyltransferase
BF27_5105	COG3615	Tellurite resistance protein tehB
BF27_5106	COG0577	efflux transmembrane transporter activity
BF27_5106	COG1136	(ABC) transporter
BF27_5109	COG1309	transcriptional regulator
BF27_5114	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_5118	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF27_5119	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF27_5120	COG2971	BadF BadG BcrA BcrD
BF27_5125	COG1649	PFAM Uncharacterised BCR, COG1649
BF27_5130	COG1595	DNA-templated transcription, initiation
BF27_5135	COG1396	sequence-specific DNA binding
BF27_5139	COG1132	(ABC) transporter
BF27_5140	COG1132	(ABC) transporter
BF27_5143	COG2258	MOSC domain
BF27_5144	COG0583	DNA-binding transcription factor activity
BF27_5147	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF27_5148	COG0583	DNA-binding transcription factor activity
BF27_515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF27_5156	COG0561	phosphatase activity
BF27_5157	COG0010	Belongs to the arginase family
BF27_5160	COG1278	Cold shock
BF27_5162	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF27_517	COG1114	Component of the transport system for branched-chain amino acids
BF27_5170	COG1247	-acetyltransferase
BF27_5177	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF27_5186	COG2226	methyltransferase
BF27_519	COG2197	response regulator
BF27_5191	COG2814	Major facilitator Superfamily
BF27_5192	COG0596	Alpha beta hydrolase
BF27_5194	COG1136	(ABC) transporter
BF27_5195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF27_5196	COG1187	pseudouridine synthase activity
BF27_5197	COG2329	Antibiotic biosynthesis monooxygenase
BF27_520	COG4585	Histidine kinase
BF27_5200	COG1115	amino acid carrier protein
BF27_5202	COG2318	DinB family
BF27_5204	COG0776	regulation of translation
BF27_5207	COG2814	Major facilitator Superfamily
BF27_5208	COG3251	PFAM MbtH domain protein
BF27_5209	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF27_521	COG4758	membrane
BF27_5210	COG3433	isochorismatase activity
BF27_5210	COG1535	isochorismatase
BF27_5211	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF27_5212	COG1169	isochorismate synthase
BF27_5213	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_5214	COG2223	nitrite transmembrane transporter activity
BF27_5218	COG0419	ATPase involved in DNA repair
BF27_5219	COG0420	3'-5' exonuclease activity
BF27_5222	COG1024	Enoyl-CoA hydratase
BF27_5223	COG1280	lysine exporter protein (LysE YggA)
BF27_5224	COG1012	belongs to the aldehyde dehydrogenase family
BF27_5225	COG2084	Dehydrogenase
BF27_5226	COG1960	acyl-CoA dehydrogenase activity
BF27_5227	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF27_5228	COG2079	MmgE PrpD family protein
BF27_5229	COG0372	Belongs to the citrate synthase family
BF27_5230	COG4841	protein insertion into membrane
BF27_5231	COG2814	Major facilitator Superfamily
BF27_5232	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF27_5232	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF27_524	COG1757	Na H antiporter
BF27_5240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF27_5256	COG1787	Restriction endonuclease
BF27_5256	COG1715	Restriction endonuclease
BF27_5261	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF27_5262	COG0671	phosphoesterase, PA-phosphatase related
BF27_5263	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF27_5264	COG4326	sporulation control protein
BF27_5272	COG1509	lysine 2,3-aminomutase activity
BF27_5273	COG3829	transcription factor binding
BF27_5274	COG0456	acetyltransferase
BF27_5275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF27_5276	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF27_5277	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF27_5278	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF27_528	COG0733	neurotransmitter:sodium symporter activity
BF27_5281	COG5506	Protein of unknown function (DUF1694)
BF27_5282	COG1012	belongs to the aldehyde dehydrogenase family
BF27_5283	COG1253	flavin adenine dinucleotide binding
BF27_529	COG1648	precorrin-2 dehydrogenase activity
BF27_5290	COG1174	glycine betaine transport
BF27_5291	COG1125	glycine betaine transport
BF27_5291	COG0517	IMP dehydrogenase activity
BF27_5298	COG1070	Carbohydrate kinase
BF27_53	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF27_5304	COG1064	alcohol dehydrogenase
BF27_5305	COG1737	Transcriptional regulator
BF27_5307	COG2197	response regulator
BF27_5308	COG4585	Histidine kinase
BF27_5308	COG2203	Gaf domain
BF27_5309	COG0668	transmembrane transport
BF27_5310	COG0071	Belongs to the small heat shock protein (HSP20) family
BF27_5311	COG1051	belongs to the nudix hydrolase family
BF27_5312	COG1335	isochorismatase
BF27_5316	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF27_5317	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF27_5321	COG0367	asparagine synthase
BF27_5322	COG0071	Belongs to the small heat shock protein (HSP20) family
BF27_5323	COG1999	signal sequence binding
BF27_5324	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF27_5325	COG1307	EDD domain protein, DegV family
BF27_5327	COG0805	protein transport
BF27_5329	COG1272	protein, Hemolysin III
BF27_533	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF27_5330	COG0204	Acyl-transferase
BF27_5331	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF27_5332	COG0768	penicillin binding
BF27_5335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF27_5339	COG0546	phosphoglycolate phosphatase activity
BF27_534	COG0529	Catalyzes the synthesis of activated sulfate
BF27_5341	COG4473	ABC transporter
BF27_5342	COG1131	(ABC) transporter
BF27_5344	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF27_5346	COG0456	acetyltransferase
BF27_5348	COG1794	racemase activity, acting on amino acids and derivatives
BF27_5349	COG1454	alcohol dehydrogenase
BF27_5350	COG2610	gluconate transmembrane transporter activity
BF27_5355	COG0733	neurotransmitter:sodium symporter activity
BF27_5358	COG3850	Histidine kinase
BF27_5358	COG5002	protein histidine kinase activity
BF27_5359	COG0745	RESPONSE REGULATOR receiver
BF27_5360	COG0471	metal ion transport
BF27_5361	COG1929	Belongs to the glycerate kinase type-1 family
BF27_5378	COG1674	ftsk spoiiie
BF27_538	COG0019	diaminopimelate decarboxylase activity
BF27_5382	COG0017	Asparaginyl-tRNA synthetase
BF27_5383	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF27_5386	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF27_5392	COG0018	arginyl-trna synthetase
BF27_5393	COG2136	Putative SAM-dependent methyltransferase
BF27_5393	COG2521	methyltransferase
BF27_5396	COG1413	lyase activity
BF27_5397	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF27_54	COG2223	nitrite transmembrane transporter activity
BF27_540	COG1368	sulfuric ester hydrolase activity
BF27_5400	COG0629	single-stranded DNA binding
BF27_5403	COG0488	(ABC) transporter
BF27_5404	COG1418	mRNA catabolic process
BF27_5407	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF27_541	COG1183	phosphatidylcholine synthase activity
BF27_5410	COG2359	stage V sporulation protein S
BF27_5417	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF27_5418	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF27_5419	COG2146	nitrite reductase [NAD(P)H] activity
BF27_5420	COG1587	Uroporphyrinogen-III synthase
BF27_5420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF27_5422	COG1648	precorrin-2 dehydrogenase activity
BF27_5425	COG2223	nitrite transmembrane transporter activity
BF27_5427	COG0314	molybdopterin synthase activity
BF27_5428	COG0303	'Molybdopterin
BF27_5429	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF27_5430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF27_5431	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF27_5433	COG1131	(ABC) transporter
BF27_5435	COG2181	nitrate reductase activity
BF27_5436	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF27_5437	COG1140	nitrate reductase beta subunit
BF27_5438	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF27_544	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF27_5441	COG0714	Associated with various cellular activities
BF27_5442	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF27_5443	COG1305	Transglutaminase-like
BF27_5444	COG0386	Belongs to the glutathione peroxidase family
BF27_5449	COG1595	DNA-templated transcription, initiation
BF27_5450	COG0604	alcohol dehydrogenase
BF27_5452	COG0346	lactoylglutathione lyase activity
BF27_5453	COG1082	Xylose isomerase domain protein TIM barrel
BF27_5457	COG2226	methyltransferase
BF27_5462	COG3874	Sporulation protein YtfJ
BF27_5471	COG0456	acetyltransferase
BF27_5477	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF27_5478	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_5479	COG1819	glycosyl
BF27_5483	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF27_5485	COG0561	phosphatase activity
BF27_5489	COG2211	Major facilitator Superfamily
BF27_5490	COG0154	amidase activity
BF27_5492	COG1876	peptidase activity
BF27_5494	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF27_5498	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF27_5499	COG1114	Component of the transport system for branched-chain amino acids
BF27_55	COG4166	transmembrane transport
BF27_5502	COG1253	flavin adenine dinucleotide binding
BF27_5503	COG2839	Protein conserved in bacteria
BF27_5504	COG0702	epimerase
BF27_5507	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF27_5508	COG1607	acyl-coa hydrolase
BF27_5509	COG3689	TIGRFAM TIGR03943 family protein
BF27_551	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF27_5510	COG0701	Predicted permease
BF27_5512	COG2244	polysaccharide biosynthetic process
BF27_5513	COG0586	Pfam SNARE associated Golgi protein
BF27_5514	COG1051	belongs to the nudix hydrolase family
BF27_5515	COG5337	Spore coat protein CotH
BF27_5517	COG0406	alpha-ribazole phosphatase activity
BF27_5520	COG4166	transmembrane transport
BF27_5522	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF27_5524	COG0702	epimerase
BF27_5526	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF27_5526	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF27_5537	COG0456	acetyltransferase
BF27_5538	COG0523	cobalamin synthesis protein
BF27_5539	COG4989	oxidoreductase activity
BF27_5541	COG1231	oxidoreductase activity
BF27_5543	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF27_5546	COG0783	Belongs to the Dps family
BF27_5547	COG3949	Membrane
BF27_5550	COG0840	transmembrane signaling receptor activity
BF27_5555	COG2814	Major facilitator Superfamily
BF27_5556	COG0667	Aldo Keto reductase
BF27_5557	COG0640	Transcriptional regulator
BF27_5558	COG1404	Belongs to the peptidase S8 family
BF27_5559	COG2002	toxin-antitoxin pair type II binding
BF27_556	COG0473	3-isopropylmalate dehydrogenase activity
BF27_5560	COG0577	efflux transmembrane transporter activity
BF27_5567	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF27_5569	COG1279	arginine transmembrane transporter activity
BF27_5570	COG2814	Major facilitator Superfamily
BF27_5572	COG1082	Xylose isomerase domain protein TIM barrel
BF27_5575	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_5576	COG4264	IucA IucC family
BF27_5578	COG1247	-acetyltransferase
BF27_5579	COG1285	pathogenesis
BF27_558	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF27_5581	COG0726	polysaccharide deacetylase
BF27_5582	COG5002	protein histidine kinase activity
BF27_5583	COG0745	RESPONSE REGULATOR receiver
BF27_5585	COG1316	TRANSCRIPTIONal
BF27_559	COG0440	acetolactate synthase activity
BF27_5590	COG0460	homoserine dehydrogenase
BF27_5594	COG0726	polysaccharide deacetylase
BF27_5596	COG0300	oxidoreductase activity
BF27_5598	COG5002	protein histidine kinase activity
BF27_5599	COG0745	RESPONSE REGULATOR receiver
BF27_56	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF27_560	COG0028	Belongs to the TPP enzyme family
BF27_5600	COG1132	(ABC) transporter
BF27_5602	COG1388	LysM domain
BF27_5602	COG0791	NLP P60 protein
BF27_5604	COG1686	Belongs to the peptidase S11 family
BF27_5608	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF27_5609	COG4988	ABC transporter
BF27_561	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF27_5610	COG1294	oxidase, subunit
BF27_5611	COG1271	oxidase subunit
BF27_5613	COG1846	Transcriptional regulator
BF27_5615	COG1942	4-Oxalocrotonate Tautomerase
BF27_5617	COG0583	DNA-binding transcription factor activity
BF27_5621	COG0411	ABC transporter
BF27_5623	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_5624	COG2030	dehydratase
BF27_5625	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_5628	COG0523	cobalamin synthesis protein
BF27_5629	COG1231	oxidoreductase activity
BF27_5630	COG0039	L-malate dehydrogenase activity
BF27_5631	COG0628	permease
BF27_5635	COG0778	Nitroreductase
BF27_5636	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF27_5637	COG1959	2 iron, 2 sulfur cluster binding
BF27_5638	COG0583	DNA-binding transcription factor activity
BF27_5639	COG0697	spore germination
BF27_5641	COG4549	nuclear export factor GLE1
BF27_5642	COG1276	copper resistance
BF27_5642	COG2372	response to copper ion
BF27_5644	COG1114	Component of the transport system for branched-chain amino acids
BF27_5645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF27_5651	COG2132	Multicopper oxidase
BF27_5652	COG0006	proline dipeptidase activity
BF27_5658	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF27_5659	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF27_566	COG3874	Sporulation protein YtfJ
BF27_5661	COG2390	Transcriptional regulator
BF27_567	COG4709	membrane
BF27_568	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF27_569	COG1301	dicarboxylic acid transport
BF27_571	COG1846	Transcriptional regulator
BF27_5716	COG4962	Type ii secretion system protein e
BF27_574	COG1968	undecaprenyl-diphosphatase activity
BF27_5746	COG2311	Membrane
BF27_575	COG0534	Mate efflux family protein
BF27_5752	COG4196	transglutaminase domain protein
BF27_5753	COG0671	phosphoesterase, PA-phosphatase related
BF27_5755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF27_5760	COG2801	Transposase and inactivated derivatives
BF27_579	COG3173	Aminoglycoside phosphotransferase
BF27_5795	COG2002	toxin-antitoxin pair type II binding
BF27_5798	COG4974	Belongs to the 'phage' integrase family
BF27_58	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_5807	COG2801	Transposase and inactivated derivatives
BF27_5810	COG2801	Transposase and inactivated derivatives
BF27_5814	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF27_5816	COG4974	Belongs to the 'phage' integrase family
BF27_582	COG0716	FMN binding
BF27_5821	COG0457	Tetratricopeptide repeat
BF27_5823	COG1923	regulation of RNA biosynthetic process
BF27_5843	COG3344	reverse transcriptase
BF27_587	COG1696	Membrane protein involved in D-alanine export
BF27_5889	COG1192	Involved in chromosome partitioning
BF27_589	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF27_5895	COG2801	Transposase and inactivated derivatives
BF27_59	COG0477	Major facilitator Superfamily
BF27_590	COG2070	2-Nitropropane dioxygenase
BF27_5901	COG1683	Conserved Protein
BF27_5902	COG1309	transcriptional regulator
BF27_591	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF27_5919	COG0681	Belongs to the peptidase S26 family
BF27_5926	COG1280	lysine exporter protein (LysE YggA)
BF27_593	COG1335	isochorismatase
BF27_5932	COG4166	transmembrane transport
BF27_5935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF27_5946	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF27_5947	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF27_595	COG1522	sequence-specific DNA binding
BF27_5962	COG0791	NLP P60 protein
BF27_5962	COG0741	lytic transglycosylase activity
BF27_598	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF27_599	COG1131	(ABC) transporter
BF27_601	COG1131	(ABC) transporter
BF27_602	COG1725	Transcriptional regulator
BF27_603	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF27_604	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF27_606	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF27_607	COG1780	Probably involved in ribonucleotide reductase function
BF27_61	COG1966	Carbon starvation protein
BF27_613	COG4873	Protein conserved in bacteria
BF27_616	COG0720	synthase
BF27_618	COG2205	protein histidine kinase activity
BF27_619	COG5002	protein histidine kinase activity
BF27_621	COG2318	DinB family
BF27_623	COG1846	Transcriptional regulator
BF27_624	COG3852	Histidine kinase
BF27_626	COG2861	carbohydrate metabolic process
BF27_633	COG1349	DNA-binding transcription factor activity
BF27_636	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF27_639	COG3842	ATPase activity
BF27_640	COG3842	ATPase activity
BF27_642	COG1840	ABC-type Fe3 transport system, periplasmic component
BF27_645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF27_647	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF27_648	COG1028	Short-chain dehydrogenase reductase Sdr
BF27_652	COG2030	dehydratase
BF27_654	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF27_655	COG0861	Integral membrane protein TerC family
BF27_656	COG2116	formate transmembrane transporter activity
BF27_658	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF27_66	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF27_662	COG2186	Transcriptional regulator
BF27_663	COG5002	protein histidine kinase activity
BF27_664	COG0745	RESPONSE REGULATOR receiver
BF27_666	COG3835	regulator
BF27_667	COG0277	FAD linked oxidase domain protein
BF27_668	COG0247	lactate metabolic process
BF27_669	COG2340	Cysteine-rich secretory protein family
BF27_67	COG1051	belongs to the nudix hydrolase family
BF27_671	COG0564	pseudouridine synthase activity
BF27_673	COG2409	Drug exporters of the RND superfamily
BF27_675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF27_676	COG1177	transmembrane transport
BF27_677	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF27_678	COG3842	ATPase activity
BF27_679	COG1012	belongs to the aldehyde dehydrogenase family
BF27_686	COG0681	Belongs to the peptidase S26 family
BF27_687	COG1686	Belongs to the peptidase S11 family
BF27_689	COG2226	methyltransferase
BF27_7	COG1914	H( )-stimulated, divalent metal cation uptake system
BF27_700	COG1476	TRANSCRIPTIONal
BF27_702	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF27_712	COG5634	Uncharacterized conserved protein (DUF2278)
BF27_713	COG1620	l-lactate permease
BF27_720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF27_720	COG0512	Glutamine amidotransferase of anthranilate synthase
BF27_723	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF27_724	COG5492	domain, Protein
BF27_727	COG2382	esterase
BF27_728	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF27_729	COG2153	protein acetylation
BF27_737	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF27_740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF27_749	COG1216	Glycosyl transferase, family 2
BF27_750	COG0772	Belongs to the SEDS family
BF27_753	COG0564	pseudouridine synthase activity
BF27_754	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF27_755	COG2357	RelA SpoT domain protein
BF27_757	COG4116	CYTH
BF27_758	COG2346	COG2346, Truncated hemoglobins
BF27_764	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF27_765	COG4862	establishment of competence for transformation
BF27_766	COG0861	Integral membrane protein TerC family
BF27_767	COG1393	Belongs to the ArsC family
BF27_769	COG4166	transmembrane transport
BF27_77	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF27_770	COG0534	Mate efflux family protein
BF27_771	COG4608	Belongs to the ABC transporter superfamily
BF27_772	COG0444	Belongs to the ABC transporter superfamily
BF27_773	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF27_774	COG0601	transmembrane transport
BF27_775	COG4166	transmembrane transport
BF27_777	COG0180	Tryptophanyl-tRNA synthetase
BF27_779	COG5504	Zn-dependent protease
BF27_78	COG0784	Response regulator, receiver
BF27_780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF27_781	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF27_784	COG2267	carboxylic ester hydrolase activity
BF27_786	COG0542	response to heat
BF27_788	COG0561	phosphatase activity
BF27_79	COG4191	Histidine kinase
BF27_791	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF27_793	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF27_795	COG2996	Protein conserved in bacteria
BF27_799	COG0004	ammonium transporteR
BF27_80	COG0281	malic enzyme
BF27_800	COG0753	catalase activity
BF27_802	COG0367	asparagine synthase
BF27_807	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF27_81	COG1027	Aspartate ammonia-lyase
BF27_816	COG1074	ATP-dependent DNA helicase activity
BF27_817	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF27_819	COG0398	Pfam SNARE associated Golgi protein
BF27_820	COG4903	ComK protein
BF27_823	COG1278	Cold shock
BF27_825	COG2224	Isocitrate lyase
BF27_826	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF27_827	COG0497	DNA recombination
BF27_83	COG0528	UMP kinase activity
BF27_830	COG0697	spore germination
BF27_831	COG0840	transmembrane signaling receptor activity
BF27_832	COG0501	Belongs to the peptidase M48B family
BF27_837	COG0745	RESPONSE REGULATOR receiver
BF27_838	COG2205	protein histidine kinase activity
BF27_84	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF27_840	COG3708	Transcriptional regulator
BF27_840	COG2207	Transcriptional regulator
BF27_841	COG1595	DNA-templated transcription, initiation
BF27_843	COG1078	dGTPase activity
BF27_844	COG1408	metallophosphoesterase
BF27_850	COG3209	COG3209 Rhs family protein
BF27_856	COG0318	PFAM AMP-dependent synthetase and ligase
BF27_858	COG0095	Lipoate-protein ligase
BF27_859	COG1234	tRNA 3'-trailer cleavage
BF27_861	COG1609	Transcriptional regulator
BF27_866	COG1511	domain protein
BF27_867	COG1309	transcriptional regulator
BF27_87	COG1131	(ABC) transporter
BF27_876	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF27_877	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF27_878	COG2329	Antibiotic biosynthesis monooxygenase
BF27_881	COG3402	PFAM membrane-flanked domain
BF27_889	COG3428	Bacterial PH domain
BF27_890	COG3402	PFAM membrane-flanked domain
BF27_892	COG1309	transcriptional regulator
BF27_895	COG4473	ABC transporter
BF27_896	COG1131	(ABC) transporter
BF27_897	COG0537	adenosine 5'-monophosphoramidase activity
BF27_898	COG4980	gas vesicle protein
BF27_902	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF27_903	COG3973	AAA domain
BF27_905	COG0477	Major facilitator Superfamily
BF27_906	COG0477	Major facilitator Superfamily
BF27_914	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF27_916	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF27_917	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF27_918	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF27_922	COG2267	carboxylic ester hydrolase activity
BF27_924	COG0457	Tetratricopeptide repeat
BF27_925	COG0346	lactoylglutathione lyase activity
BF27_926	COG0346	lactoylglutathione lyase activity
BF27_927	COG2814	Major facilitator Superfamily
BF27_928	COG1309	transcriptional regulator
BF27_93	COG2733	membrane
BF27_932	COG4717	serine-type aminopeptidase activity
BF27_933	COG0420	3'-5' exonuclease activity
BF27_939	COG0393	Putative heavy-metal-binding
BF27_944	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF27_944	COG0784	Response regulator, receiver
BF27_944	COG2205	protein histidine kinase activity
BF27_944	COG2198	Histidine kinase
BF27_945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF27_946	COG2208	phosphoserine phosphatase activity
BF27_948	COG1191	sigma factor activity
BF27_953	COG3237	CsbD-like
BF27_963	COG2770	Histidine kinase
BF27_963	COG3437	response regulator, receiver
BF27_968	COG1959	2 iron, 2 sulfur cluster binding
BF27_969	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF27_970	COG2376	Dihydroxyacetone kinase
BF27_972	COG2376	Dihydroxyacetone kinase
BF27_976	COG1183	phosphatidylcholine synthase activity
BF27_981	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF27_981	COG3320	Male sterility
BF27_991	COG0477	Major facilitator Superfamily
BF27_999	COG0305	Participates in initiation and elongation during chromosome replication