locus-tag	class	description
KM390_00010	COG0592	DNA-directed DNA polymerase activity
KM390_00015	COG2501	S4 domain
KM390_00025	COG0187	DNA topoisomerase II activity
KM390_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM390_00065	COG0516	GMP reductase activity
KM390_00065	COG0517	IMP dehydrogenase activity
KM390_00070	COG1686	Belongs to the peptidase S11 family
KM390_00100	COG1428	Deoxynucleoside kinase
KM390_00105	COG1428	Deoxynucleoside kinase
KM390_00110	COG1335	isochorismatase
KM390_00115	COG0590	tRNA wobble adenosine to inosine editing
KM390_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM390_00180	COG1982	Orn Lys Arg decarboxylase major
KM390_00190	COG0470	DNA polymerase III
KM390_00195	COG1774	PSP1 C-terminal conserved region
KM390_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM390_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM390_00220	COG2002	toxin-antitoxin pair type II binding
KM390_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM390_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM390_00230	COG0084	hydrolase, TatD family'
KM390_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM390_00250	COG4466	Protein conserved in bacteria
KM390_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM390_00270	COG0251	oxidation-reduction process
KM390_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM390_00305	COG2002	toxin-antitoxin pair type II binding
KM390_00310	COG2244	polysaccharide biosynthetic process
KM390_00315	COG3956	TIGRFAM MazG family protein
KM390_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM390_00340	COG1098	S1 RNA binding domain
KM390_00355	COG2208	phosphoserine phosphatase activity
KM390_00360	COG0037	tRNA processing
KM390_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM390_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM390_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM390_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM390_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM390_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM390_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM390_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM390_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM390_00420	COG1396	sequence-specific DNA binding
KM390_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM390_00455	COG3880	PFAM UvrB UvrC protein
KM390_00465	COG0542	response to heat
KM390_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM390_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM390_00500	COG1045	serine acetyltransferase
KM390_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM390_00520	COG3688	RNA-binding protein containing a PIN domain
KM390_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM390_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM390_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM390_00565	COG2813	Specifically methylates the guanine in position
KM390_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM390_00580	COG1358	cellular component organization or biogenesis
KM390_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM390_00710	COG0201	protein transport
KM390_00720	COG0024	Methionine aminopeptidase
KM390_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM390_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM390_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM390_00795	COG0489	protein tyrosine kinase activity
KM390_00805	COG2194	sulfuric ester hydrolase activity
KM390_00810	COG0726	polysaccharide deacetylase
KM390_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM390_00895	COG4856	YbbR-like protein
KM390_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM390_00915	COG0596	Alpha beta hydrolase
KM390_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM390_00940	COG1506	peptidase
KM390_00940	COG4946	Tricorn protease homolog
KM390_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM390_00975	COG2011	ABC-type metal ion transport system permease component
KM390_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM390_00985	COG1464	Belongs to the NlpA lipoprotein family
KM390_00990	COG0604	alcohol dehydrogenase
KM390_01000	COG0277	FAD linked oxidase domain protein
KM390_01005	COG2271	Major facilitator Superfamily
KM390_01015	COG2814	Major facilitator Superfamily
KM390_01030	COG0601	transmembrane transport
KM390_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM390_01040	COG0444	Belongs to the ABC transporter superfamily
KM390_01045	COG4608	Belongs to the ABC transporter superfamily
KM390_01050	COG4166	transmembrane transport
KM390_01060	COG2207	Transcriptional regulator
KM390_01075	COG4166	transmembrane transport
KM390_01080	COG4166	transmembrane transport
KM390_01085	COG0656	L-ascorbic acid biosynthetic process
KM390_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM390_01105	COG4149	molybdate abc transporter
KM390_01115	COG1910	domain protein
KM390_01125	COG0583	DNA-binding transcription factor activity
KM390_01130	COG0697	spore germination
KM390_01145	COG0204	Acyl-transferase
KM390_01155	COG1609	Transcriptional regulator
KM390_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_01175	COG0084	hydrolase, TatD family'
KM390_01180	COG5298	Protein conserved in bacteria
KM390_01205	COG0488	(ABC) transporter
KM390_01220	COG0747	negative chemotaxis
KM390_01225	COG0601	transmembrane transport
KM390_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM390_01235	COG0444	Belongs to the ABC transporter superfamily
KM390_01240	COG4608	Belongs to the ABC transporter superfamily
KM390_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM390_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM390_01290	COG2814	Major facilitator Superfamily
KM390_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM390_01310	COG4294	response to UV
KM390_01315	COG0457	Tetratricopeptide repeat
KM390_01315	COG0705	Rhomboid family
KM390_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM390_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM390_01335	COG0864	Transcriptional regulator
KM390_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM390_01345	COG2183	response to ionizing radiation
KM390_01440	COG0802	atpase or kinase
KM390_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM390_01450	COG0456	acetyltransferase
KM390_01460	COG0488	(ABC) transporter
KM390_01475	COG1266	CAAX protease self-immunity
KM390_01495	COG2252	PERMEase
KM390_01505	COG5002	protein histidine kinase activity
KM390_01535	COG2226	methyltransferase
KM390_01575	COG1968	undecaprenyl-diphosphatase activity
KM390_01590	COG2205	protein histidine kinase activity
KM390_01595	COG0745	RESPONSE REGULATOR receiver
KM390_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM390_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM390_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM390_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM390_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM390_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM390_01670	COG0151	Belongs to the GarS family
KM390_01695	COG0210	DNA helicase
KM390_01705	COG4851	CamS sex pheromone cAM373 precursor
KM390_01725	COG1335	isochorismatase
KM390_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM390_01735	COG2011	ABC-type metal ion transport system permease component
KM390_01740	COG1464	Belongs to the NlpA lipoprotein family
KM390_01760	COG1846	Transcriptional regulator
KM390_01785	COG1597	lipid kinase activity
KM390_01790	COG0546	phosphoglycolate phosphatase activity
KM390_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM390_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM390_01810	COG2076	Multidrug Resistance protein
KM390_01815	COG2309	aminopeptidase activity
KM390_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM390_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM390_01850	COG4807	Protein conserved in bacteria
KM390_01875	COG1757	Na H antiporter
KM390_01880	COG1473	amidohydrolase
KM390_01895	COG0450	alkyl hydroperoxide reductase
KM390_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_01940	COG0166	Belongs to the GPI family
KM390_01975	COG5002	protein histidine kinase activity
KM390_01995	COG3541	Predicted nucleotidyltransferase
KM390_02000	COG2814	Major facilitator Superfamily
KM390_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM390_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM390_02015	COG0765	amino acid transport
KM390_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM390_02030	COG0840	transmembrane signaling receptor activity
KM390_02035	COG0840	transmembrane signaling receptor activity
KM390_02040	COG0366	Alpha amylase catalytic
KM390_02045	COG1263	PTS System
KM390_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_02045	COG2190	(PTS) system
KM390_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM390_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM390_02100	COG1116	anion transmembrane transporter activity
KM390_02105	COG0488	(ABC) transporter
KM390_02150	COG2270	Major facilitator Superfamily
KM390_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM390_02180	COG2310	stress, protein
KM390_02185	COG2310	stress, protein
KM390_02190	COG2310	stress, protein
KM390_02195	COG0861	Integral membrane protein TerC family
KM390_02205	COG3853	Toxic anion resistance protein (TelA)
KM390_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM390_02230	COG1295	ribonuclease BN
KM390_02235	COG2217	Heavy metal translocating P-type atpase
KM390_02240	COG0697	spore germination
KM390_02260	COG0586	Pfam SNARE associated Golgi protein
KM390_02275	COG3871	stress protein (general stress protein 26)
KM390_02280	COG0387	Pfam Sodium calcium exchanger
KM390_02290	COG0535	radical SAM domain protein
KM390_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM390_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM390_02325	COG0582	viral genome integration into host DNA
KM390_02335	COG1396	sequence-specific DNA binding
KM390_02350	COG1396	sequence-specific DNA binding
KM390_02385	COG1484	DNA-dependent DNA replication
KM390_02615	COG0101	tRNA pseudouridine synthase activity
KM390_02625	COG3829	transcription factor binding
KM390_02635	COG0833	amino acid
KM390_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM390_02670	COG1263	PTS System
KM390_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM390_02690	COG0463	Glycosyl transferase, family 2
KM390_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM390_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM390_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM390_02745	COG1228	amidohydrolase
KM390_02750	COG1090	epimerase
KM390_02780	COG1988	membrane-bound metal-dependent
KM390_02785	COG1194	a g-specific adenine glycosylase
KM390_02810	COG1132	(ABC) transporter
KM390_02815	COG4129	membrane
KM390_02820	COG0069	glutamate synthase activity
KM390_02820	COG0067	glutamate synthase
KM390_02820	COG0070	glutamate synthase
KM390_02830	COG4555	ABC transporter
KM390_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM390_02855	COG0735	belongs to the Fur family
KM390_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM390_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM390_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM390_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM390_03005	COG2766	serine protein kinase
KM390_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM390_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM390_03040	COG2268	Band 7 protein
KM390_03050	COG3290	protein histidine kinase activity
KM390_03055	COG4565	transcriptional regulatory protein
KM390_03060	COG2851	Citrate transporter
KM390_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM390_03085	COG3842	ATPase activity
KM390_03090	COG1175	transmembrane transport
KM390_03095	COG0395	ABC-type sugar transport system, permease component
KM390_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM390_03110	COG0745	RESPONSE REGULATOR receiver
KM390_03115	COG5002	protein histidine kinase activity
KM390_03125	COG4990	cell redox homeostasis
KM390_03135	COG3290	protein histidine kinase activity
KM390_03140	COG4565	transcriptional regulatory protein
KM390_03145	COG3493	citrate carrier protein
KM390_03150	COG0281	malic enzyme
KM390_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_03175	COG5002	protein histidine kinase activity
KM390_03180	COG0745	RESPONSE REGULATOR receiver
KM390_03185	COG0454	-acetyltransferase
KM390_03185	COG0456	acetyltransferase
KM390_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM390_03195	COG3383	formate dehydrogenase (NAD+) activity
KM390_03200	COG2427	Protein of unknown function (DUF1641)
KM390_03215	COG0531	amino acid
KM390_03220	COG0640	Transcriptional regulator
KM390_03225	COG2217	Heavy metal translocating P-type atpase
KM390_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM390_03245	COG3227	Zinc metalloprotease (Elastase)
KM390_03265	COG2720	vancomycin resistance protein
KM390_03270	COG1316	TRANSCRIPTIONal
KM390_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_03280	COG0346	lactoylglutathione lyase activity
KM390_03285	COG1253	flavin adenine dinucleotide binding
KM390_03290	COG1027	Aspartate ammonia-lyase
KM390_03295	COG1620	l-lactate permease
KM390_03310	COG3104	oligopeptide transport
KM390_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_03335	COG2226	methyltransferase
KM390_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM390_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM390_03355	COG4548	von Willebrand factor, type A
KM390_03360	COG0714	Associated with various cellular activities
KM390_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM390_03385	COG0531	amino acid
KM390_03390	COG2188	Transcriptional regulator
KM390_03395	COG1263	PTS System
KM390_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_03400	COG0366	Alpha amylase catalytic
KM390_03415	COG0697	spore germination
KM390_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM390_03430	COG1115	amino acid carrier protein
KM390_03435	COG1126	abc transporter atp-binding protein
KM390_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM390_03445	COG0765	amino acid transport
KM390_03450	COG0765	amino acid transport
KM390_03455	COG0833	amino acid
KM390_03480	COG2378	regulation of single-species biofilm formation
KM390_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM390_03490	COG5002	protein histidine kinase activity
KM390_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM390_03520	COG0747	negative chemotaxis
KM390_03530	COG0601	transmembrane transport
KM390_03535	COG4608	Belongs to the ABC transporter superfamily
KM390_03545	COG2271	Major facilitator Superfamily
KM390_03550	COG1846	Transcriptional regulator
KM390_03560	COG1609	Transcriptional regulator
KM390_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM390_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM390_03585	COG1879	ABC-type sugar transport system periplasmic component
KM390_03610	COG1063	alcohol dehydrogenase
KM390_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM390_03650	COG1968	undecaprenyl-diphosphatase activity
KM390_03655	COG0840	transmembrane signaling receptor activity
KM390_03660	COG3584	3D domain protein
KM390_03660	COG1388	LysM domain
KM390_03665	COG1476	TRANSCRIPTIONal
KM390_03680	COG3104	oligopeptide transport
KM390_03685	COG1114	Component of the transport system for branched-chain amino acids
KM390_03700	COG1113	amino acid transport
KM390_03705	COG2252	PERMEase
KM390_03730	COG0475	glutathione-regulated potassium exporter activity
KM390_03730	COG0569	domain protein
KM390_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM390_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM390_03755	COG0833	amino acid
KM390_03760	COG4990	cell redox homeostasis
KM390_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM390_03780	COG0697	spore germination
KM390_03785	COG0531	amino acid
KM390_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM390_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM390_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM390_03805	COG1918	ferrous iron import across plasma membrane
KM390_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM390_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM390_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM390_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM390_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM390_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM390_03975	COG1116	anion transmembrane transporter activity
KM390_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM390_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM390_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM390_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM390_04000	COG2104	thiamine diphosphate biosynthetic process
KM390_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM390_04015	COG0351	phosphomethylpyrimidine kinase
KM390_04055	COG2205	protein histidine kinase activity
KM390_04060	COG2814	Major facilitator Superfamily
KM390_04065	COG1846	Transcriptional regulator
KM390_04080	COG2252	PERMEase
KM390_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM390_04105	COG1621	beta-fructofuranosidase activity
KM390_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_04110	COG1263	PTS System
KM390_04115	COG1609	Transcriptional regulator
KM390_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM390_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM390_04165	COG0778	Nitroreductase
KM390_04170	COG2719	SpoVR family
KM390_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM390_04200	COG1937	Protein conserved in bacteria
KM390_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM390_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM390_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM390_04235	COG0730	response to heat
KM390_04245	COG1316	TRANSCRIPTIONal
KM390_04250	COG0604	alcohol dehydrogenase
KM390_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM390_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM390_04270	COG3711	transcriptional antiterminator
KM390_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM390_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM390_04300	COG1388	LysM domain
KM390_04300	COG3584	3D domain protein
KM390_04305	COG0577	efflux transmembrane transporter activity
KM390_04310	COG1136	(ABC) transporter
KM390_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM390_04335	COG1114	Component of the transport system for branched-chain amino acids
KM390_04340	COG3546	catalase activity
KM390_04375	COG0586	Pfam SNARE associated Golgi protein
KM390_04410	COG0531	amino acid
KM390_04415	COG0475	glutathione-regulated potassium exporter activity
KM390_04425	COG1737	Transcriptional regulator
KM390_04435	COG1263	PTS System
KM390_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_04445	COG2259	Doxx family
KM390_04460	COG0697	spore germination
KM390_04465	COG1522	sequence-specific DNA binding
KM390_04480	COG2076	Multidrug Resistance protein
KM390_04485	COG1309	transcriptional regulator
KM390_04490	COG2814	Major facilitator Superfamily
KM390_04495	COG1733	regulation of RNA biosynthetic process
KM390_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM390_04510	COG4533	DNA binding
KM390_04515	COG2211	Major facilitator Superfamily
KM390_04525	COG0693	protein deglycase activity
KM390_04530	COG0693	protein deglycase activity
KM390_04530	COG0753	catalase activity
KM390_04540	COG0531	amino acid
KM390_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM390_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM390_04560	COG1132	(ABC) transporter
KM390_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM390_04575	COG0765	amino acid transport
KM390_04580	COG1126	abc transporter atp-binding protein
KM390_04595	COG0189	ligase activity
KM390_04625	COG0028	Belongs to the TPP enzyme family
KM390_04630	COG3527	Alpha-acetolactate decarboxylase
KM390_04645	COG0561	phosphatase activity
KM390_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM390_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM390_04695	COG0653	protein targeting
KM390_04700	COG2244	polysaccharide biosynthetic process
KM390_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM390_04715	COG4196	transglutaminase domain protein
KM390_04730	COG1696	Membrane protein involved in D-alanine export
KM390_04745	COG1024	Enoyl-CoA hydratase
KM390_04765	COG1363	Peptidase, m42
KM390_04785	COG3938	Belongs to the proline racemase family
KM390_04825	COG0601	transmembrane transport
KM390_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM390_04840	COG4608	Belongs to the ABC transporter superfamily
KM390_04845	COG0322	excinuclease ABC activity
KM390_04875	COG0477	Major facilitator Superfamily
KM390_04880	COG3290	protein histidine kinase activity
KM390_04885	COG4565	transcriptional regulatory protein
KM390_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM390_04920	COG0789	Transcriptional regulator
KM390_04920	COG4978	Transcriptional regulator
KM390_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM390_04975	COG0477	Major facilitator Superfamily
KM390_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM390_05020	COG3320	Male sterility
KM390_05025	COG1309	transcriptional regulator
KM390_05045	COG1183	phosphatidylcholine synthase activity
KM390_05065	COG2376	Dihydroxyacetone kinase
KM390_05075	COG2376	Dihydroxyacetone kinase
KM390_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM390_05085	COG1959	2 iron, 2 sulfur cluster binding
KM390_05115	COG2770	Histidine kinase
KM390_05115	COG3437	response regulator, receiver
KM390_05165	COG3237	CsbD-like
KM390_05190	COG1191	sigma factor activity
KM390_05200	COG2208	phosphoserine phosphatase activity
KM390_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM390_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM390_05210	COG2198	Histidine kinase
KM390_05210	COG0784	Response regulator, receiver
KM390_05210	COG2205	protein histidine kinase activity
KM390_05265	COG0420	3'-5' exonuclease activity
KM390_05270	COG4717	serine-type aminopeptidase activity
KM390_05290	COG1309	transcriptional regulator
KM390_05295	COG2814	Major facilitator Superfamily
KM390_05300	COG0346	lactoylglutathione lyase activity
KM390_05310	COG0346	lactoylglutathione lyase activity
KM390_05315	COG0457	Tetratricopeptide repeat
KM390_05320	COG2267	carboxylic ester hydrolase activity
KM390_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM390_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM390_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM390_05395	COG0477	Major facilitator Superfamily
KM390_05400	COG0477	Major facilitator Superfamily
KM390_05410	COG3973	AAA domain
KM390_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM390_05435	COG4980	gas vesicle protein
KM390_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM390_05445	COG1131	(ABC) transporter
KM390_05450	COG4473	ABC transporter
KM390_05465	COG1309	transcriptional regulator
KM390_05475	COG3402	PFAM membrane-flanked domain
KM390_05525	COG3402	PFAM membrane-flanked domain
KM390_05530	COG3428	Bacterial PH domain
KM390_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM390_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM390_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM390_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM390_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM390_05590	COG1309	transcriptional regulator
KM390_05595	COG1511	domain protein
KM390_05620	COG1609	Transcriptional regulator
KM390_05630	COG1234	tRNA 3'-trailer cleavage
KM390_05635	COG0095	Lipoate-protein ligase
KM390_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_05675	COG3209	COG3209 Rhs family protein
KM390_05715	COG1078	dGTPase activity
KM390_05725	COG1595	DNA-templated transcription, initiation
KM390_05730	COG2207	Transcriptional regulator
KM390_05730	COG3708	Transcriptional regulator
KM390_05745	COG2205	protein histidine kinase activity
KM390_05750	COG0745	RESPONSE REGULATOR receiver
KM390_05775	COG0501	Belongs to the peptidase M48B family
KM390_05780	COG0840	transmembrane signaling receptor activity
KM390_05785	COG0697	spore germination
KM390_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM390_05810	COG2224	Isocitrate lyase
KM390_05835	COG4903	ComK protein
KM390_05840	COG0398	Pfam SNARE associated Golgi protein
KM390_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM390_05855	COG1074	ATP-dependent DNA helicase activity
KM390_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM390_05925	COG0367	asparagine synthase
KM390_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM390_05935	COG0753	catalase activity
KM390_05940	COG0004	ammonium transporteR
KM390_05960	COG2996	Protein conserved in bacteria
KM390_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM390_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_05995	COG0561	phosphatase activity
KM390_06005	COG0542	response to heat
KM390_06015	COG2267	carboxylic ester hydrolase activity
KM390_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM390_06040	COG5504	Zn-dependent protease
KM390_06050	COG0180	Tryptophanyl-tRNA synthetase
KM390_06060	COG4166	transmembrane transport
KM390_06065	COG0601	transmembrane transport
KM390_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM390_06075	COG0444	Belongs to the ABC transporter superfamily
KM390_06080	COG4608	Belongs to the ABC transporter superfamily
KM390_06085	COG0534	Mate efflux family protein
KM390_06090	COG4166	transmembrane transport
KM390_06105	COG0861	Integral membrane protein TerC family
KM390_06110	COG4862	establishment of competence for transformation
KM390_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM390_06125	COG1164	Oligoendopeptidase f
KM390_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM390_06140	COG2346	COG2346, Truncated hemoglobins
KM390_06145	COG4116	CYTH
KM390_06155	COG2357	RelA SpoT domain protein
KM390_06165	COG0564	pseudouridine synthase activity
KM390_06185	COG0463	Glycosyl transferase, family 2
KM390_06185	COG1216	Glycosyl transferase, family 2
KM390_06205	COG0463	Glycosyl transferase, family 2
KM390_06205	COG0457	Tetratricopeptide repeat
KM390_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM390_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM390_06285	COG2153	protein acetylation
KM390_06295	COG2382	esterase
KM390_06310	COG5492	domain, Protein
KM390_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM390_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM390_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM390_06360	COG1620	l-lactate permease
KM390_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM390_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM390_06430	COG1476	TRANSCRIPTIONal
KM390_06490	COG2226	methyltransferase
KM390_06500	COG1686	Belongs to the peptidase S11 family
KM390_06505	COG0681	Belongs to the peptidase S26 family
KM390_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM390_06545	COG3842	ATPase activity
KM390_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM390_06555	COG1177	transmembrane transport
KM390_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM390_06570	COG2409	Drug exporters of the RND superfamily
KM390_06580	COG0564	pseudouridine synthase activity
KM390_06590	COG2340	Cysteine-rich secretory protein family
KM390_06595	COG0247	lactate metabolic process
KM390_06600	COG0277	FAD linked oxidase domain protein
KM390_06605	COG3835	regulator
KM390_06615	COG0745	RESPONSE REGULATOR receiver
KM390_06620	COG5002	protein histidine kinase activity
KM390_06625	COG2186	Transcriptional regulator
KM390_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM390_06660	COG2116	formate transmembrane transporter activity
KM390_06665	COG0861	Integral membrane protein TerC family
KM390_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM390_06680	COG2030	dehydratase
KM390_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM390_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM390_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM390_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM390_06760	COG1349	DNA-binding transcription factor activity
KM390_06780	COG2861	carbohydrate metabolic process
KM390_06790	COG3852	Histidine kinase
KM390_06795	COG1846	Transcriptional regulator
KM390_06805	COG2318	DinB family
KM390_06810	COG5002	protein histidine kinase activity
KM390_06820	COG0720	synthase
KM390_06835	COG4873	Protein conserved in bacteria
KM390_06865	COG1780	Probably involved in ribonucleotide reductase function
KM390_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM390_06890	COG1725	Transcriptional regulator
KM390_06895	COG1131	(ABC) transporter
KM390_06905	COG1131	(ABC) transporter
KM390_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM390_06925	COG1522	sequence-specific DNA binding
KM390_06935	COG1335	isochorismatase
KM390_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM390_06950	COG2070	2-Nitropropane dioxygenase
KM390_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM390_06965	COG1696	Membrane protein involved in D-alanine export
KM390_06990	COG0716	FMN binding
KM390_07005	COG3173	Aminoglycoside phosphotransferase
KM390_07025	COG0534	Mate efflux family protein
KM390_07030	COG1968	undecaprenyl-diphosphatase activity
KM390_07045	COG1846	Transcriptional regulator
KM390_07055	COG1301	dicarboxylic acid transport
KM390_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM390_07065	COG4709	membrane
KM390_07070	COG3874	Sporulation protein YtfJ
KM390_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM390_07100	COG0028	Belongs to the TPP enzyme family
KM390_07105	COG0440	acetolactate synthase activity
KM390_07110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM390_07120	COG0473	3-isopropylmalate dehydrogenase activity
KM390_07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM390_07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM390_07195	COG1183	phosphatidylcholine synthase activity
KM390_07200	COG1368	sulfuric ester hydrolase activity
KM390_07210	COG0019	diaminopimelate decarboxylase activity
KM390_07230	COG0529	Catalyzes the synthesis of activated sulfate
KM390_07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM390_07255	COG1648	precorrin-2 dehydrogenase activity
KM390_07260	COG0733	neurotransmitter:sodium symporter activity
KM390_07280	COG1757	Na H antiporter
KM390_07295	COG4758	membrane
KM390_07300	COG4585	Histidine kinase
KM390_07305	COG2197	response regulator
KM390_07315	COG1114	Component of the transport system for branched-chain amino acids
KM390_07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM390_07350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM390_07350	COG1017	nitric oxide dioxygenase activity
KM390_07365	COG0730	response to heat
KM390_07370	COG0306	phosphate transporter
KM390_07375	COG1392	Phosphate transport regulator
KM390_07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM390_07395	COG3852	Histidine kinase
KM390_07400	COG1801	Protein of unknown function DUF72
KM390_07410	COG0582	viral genome integration into host DNA
KM390_07415	COG5002	protein histidine kinase activity
KM390_07435	COG0392	lysyltransferase activity
KM390_07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM390_07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM390_07455	COG1686	Belongs to the peptidase S11 family
KM390_07460	COG2715	membrane protein required for spore maturation
KM390_07465	COG0700	Nucleoside recognition
KM390_07470	COG1187	pseudouridine synthase activity
KM390_07480	COG1333	cytochrome c biogenesis protein
KM390_07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM390_07490	COG0745	RESPONSE REGULATOR receiver
KM390_07495	COG5002	protein histidine kinase activity
KM390_07500	COG2096	Adenosyltransferase
KM390_07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM390_07520	COG1141	Ferredoxin
KM390_07525	COG4955	Helix-turn-helix domain
KM390_07530	COG0514	ATP-dependent DNA helicase (RecQ)
KM390_07535	COG1266	CAAX protease self-immunity
KM390_07555	COG4862	establishment of competence for transformation
KM390_07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM390_07580	COG0492	ferredoxin-NADP+ reductase activity
KM390_07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM390_07670	COG0142	geranyltranstransferase activity
KM390_07680	COG0142	geranyltranstransferase activity
KM390_07700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM390_07705	COG0457	Tetratricopeptide repeat
KM390_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM390_07735	COG4347	Protein of unknown function (DUF1405)
KM390_07750	COG2738	Putative neutral zinc metallopeptidase
KM390_07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_07765	COG1694	Mazg nucleotide pyrophosphohydrolase
KM390_07780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM390_07785	COG0438	transferase activity, transferring glycosyl groups
KM390_07820	COG1199	ATP-dependent helicase activity
KM390_07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM390_07840	COG3935	DnaD domain protein
KM390_07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM390_07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM390_07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM390_07915	COG0116	Belongs to the methyltransferase superfamily
KM390_07925	COG1199	ATP-dependent helicase activity
KM390_07930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM390_07940	COG3173	Aminoglycoside phosphotransferase
KM390_07945	COG0024	Methionine aminopeptidase
KM390_07955	COG2233	PERMEase
KM390_07960	COG2311	Membrane
KM390_07965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM390_07975	COG0456	acetyltransferase
KM390_08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM390_08050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM390_08065	COG1215	transferase activity, transferring glycosyl groups
KM390_08070	COG0438	transferase activity, transferring glycosyl groups
KM390_08085	COG0454	-acetyltransferase
KM390_08105	COG0328	RNA-DNA hybrid ribonuclease activity
KM390_08145	COG1280	lysine exporter protein (LysE YggA)
KM390_08160	COG3162	membrane
KM390_08165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM390_08170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM390_08180	COG0475	glutathione-regulated potassium exporter activity
KM390_08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM390_08190	COG4978	Transcriptional regulator
KM390_08190	COG0789	Transcriptional regulator
KM390_08200	COG2323	membrane
KM390_08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM390_08260	COG1923	regulation of RNA biosynthetic process
KM390_08270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM390_08275	COG1360	Flagellar Motor Protein
KM390_08280	COG2201	protein-glutamate methylesterase activity
KM390_08285	COG0643	Histidine kinase
KM390_08285	COG2198	Histidine kinase
KM390_08290	COG0643	Histidine kinase
KM390_08290	COG2198	Histidine kinase
KM390_08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM390_08295	COG1776	CheC inhibitor of MCP methylation
KM390_08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM390_08330	COG1256	bacterial-type flagellum assembly
KM390_08355	COG1815	bacterial-type flagellum-dependent cell motility
KM390_08360	COG1558	bacterial-type flagellum-dependent cell motility
KM390_08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM390_08385	COG1157	protein secretion by the type III secretion system
KM390_08425	COG0784	Response regulator, receiver
KM390_08425	COG0835	chemotaxis
KM390_08435	COG0463	Glycosyl transferase, family 2
KM390_08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM390_08475	COG0741	lytic transglycosylase activity
KM390_08490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM390_08490	COG1776	CheC inhibitor of MCP methylation
KM390_08500	COG1338	Plays a role in the flagellum-specific transport system
KM390_08505	COG1987	bacterial-type flagellum assembly
KM390_08515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM390_08520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM390_08525	COG1419	protein localization to endoplasmic reticulum
KM390_08530	COG4786	Flagellar basal body rod
KM390_08535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM390_08560	COG1309	transcriptional regulator
KM390_08580	COG2329	Antibiotic biosynthesis monooxygenase
KM390_08605	COG0583	DNA-binding transcription factor activity
KM390_08610	COG3842	ATPase activity
KM390_08615	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM390_08625	COG1234	tRNA 3'-trailer cleavage
KM390_08650	COG1686	Belongs to the peptidase S11 family
KM390_08660	COG0406	alpha-ribazole phosphatase activity
KM390_08690	COG0367	asparagine synthase
KM390_08720	COG1802	Transcriptional regulator
KM390_08725	COG0697	spore germination
KM390_08730	COG0523	cobalamin synthesis protein
KM390_08735	COG0701	Predicted permease
KM390_08745	COG1216	Glycosyl transferase, family 2
KM390_08745	COG0438	transferase activity, transferring glycosyl groups
KM390_08750	COG1757	Na H antiporter
KM390_08755	COG0114	fumarate hydratase activity
KM390_08780	COG3340	Belongs to the peptidase S51 family
KM390_08800	COG0785	Cytochrome C biogenesis protein
KM390_08830	COG2733	membrane
KM390_08865	COG1131	(ABC) transporter
KM390_08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM390_08885	COG0528	UMP kinase activity
KM390_08895	COG1027	Aspartate ammonia-lyase
KM390_08900	COG0281	malic enzyme
KM390_08905	COG4191	Histidine kinase
KM390_08910	COG0784	Response regulator, receiver
KM390_08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM390_08970	COG1051	belongs to the nudix hydrolase family
KM390_08975	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM390_08985	COG2814	Major facilitator Superfamily
KM390_09000	COG1966	Carbon starvation protein
KM390_09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM390_09035	COG2223	nitrite transmembrane transporter activity
KM390_09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM390_09055	COG2244	polysaccharide biosynthetic process
KM390_09060	COG0733	neurotransmitter:sodium symporter activity
KM390_09070	COG5566	PFAM Mor transcription activator
KM390_09075	COG2323	membrane
KM390_09090	COG2084	Dehydrogenase
KM390_09105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM390_09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM390_09120	COG0028	Belongs to the TPP enzyme family
KM390_09125	COG0440	acetolactate synthase activity
KM390_09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM390_09140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM390_09165	COG2814	Major facilitator Superfamily
KM390_09170	COG3384	dioxygenase
KM390_09180	COG3279	Response regulator of the LytR AlgR family
KM390_09185	COG0427	acetyl-CoA hydrolase
KM390_09205	COG1073	alpha beta
KM390_09235	COG0535	radical SAM domain protein
KM390_09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_09260	COG1914	H( )-stimulated, divalent metal cation uptake system
KM390_09275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM390_09305	COG2390	Transcriptional regulator
KM390_09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM390_09335	COG4224	UPF0291 protein
KM390_09355	COG0006	proline dipeptidase activity
KM390_09360	COG2132	Multicopper oxidase
KM390_09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM390_09390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM390_09405	COG1276	copper resistance
KM390_09405	COG2372	response to copper ion
KM390_09410	COG4549	nuclear export factor GLE1
KM390_09420	COG0697	spore germination
KM390_09425	COG0583	DNA-binding transcription factor activity
KM390_09430	COG1959	2 iron, 2 sulfur cluster binding
KM390_09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM390_09440	COG0778	Nitroreductase
KM390_09450	COG0628	permease
KM390_09460	COG1231	oxidoreductase activity
KM390_09465	COG0523	cobalamin synthesis protein
KM390_09480	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_09485	COG2030	dehydratase
KM390_09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_09500	COG0411	ABC transporter
KM390_09520	COG0583	DNA-binding transcription factor activity
KM390_09530	COG1942	4-Oxalocrotonate Tautomerase
KM390_09540	COG1846	Transcriptional regulator
KM390_09550	COG1271	oxidase subunit
KM390_09555	COG1294	oxidase, subunit
KM390_09560	COG4988	ABC transporter
KM390_09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM390_09585	COG1686	Belongs to the peptidase S11 family
KM390_09600	COG0791	NLP P60 protein
KM390_09600	COG1388	LysM domain
KM390_09615	COG0745	RESPONSE REGULATOR receiver
KM390_09620	COG5002	protein histidine kinase activity
KM390_09630	COG0300	oxidoreductase activity
KM390_09665	COG0460	homoserine dehydrogenase
KM390_09690	COG1316	TRANSCRIPTIONal
KM390_09700	COG0745	RESPONSE REGULATOR receiver
KM390_09705	COG5002	protein histidine kinase activity
KM390_09720	COG1285	pathogenesis
KM390_09725	COG1247	-acetyltransferase
KM390_09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM390_09755	COG1082	Xylose isomerase domain protein TIM barrel
KM390_09770	COG1279	arginine transmembrane transporter activity
KM390_09780	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM390_09820	COG2002	toxin-antitoxin pair type II binding
KM390_09825	COG1404	Belongs to the peptidase S8 family
KM390_09830	COG0640	Transcriptional regulator
KM390_09835	COG0667	Aldo Keto reductase
KM390_09840	COG2814	Major facilitator Superfamily
KM390_09865	COG0840	transmembrane signaling receptor activity
KM390_09880	COG3949	Membrane
KM390_09885	COG0783	Belongs to the Dps family
KM390_09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM390_09910	COG1231	oxidoreductase activity
KM390_09920	COG4989	oxidoreductase activity
KM390_09925	COG0523	cobalamin synthesis protein
KM390_09930	COG0456	acetyltransferase
KM390_09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM390_09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM390_09995	COG0702	epimerase
KM390_10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM390_10015	COG4166	transmembrane transport
KM390_10030	COG0406	alpha-ribazole phosphatase activity
KM390_10040	COG5337	Spore coat protein CotH
KM390_10045	COG1051	belongs to the nudix hydrolase family
KM390_10050	COG0586	Pfam SNARE associated Golgi protein
KM390_10055	COG2244	polysaccharide biosynthetic process
KM390_10065	COG0701	Predicted permease
KM390_10070	COG3689	TIGRFAM TIGR03943 family protein
KM390_10075	COG1607	acyl-coa hydrolase
KM390_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM390_10100	COG0702	epimerase
KM390_10105	COG2839	Protein conserved in bacteria
KM390_10110	COG1253	flavin adenine dinucleotide binding
KM390_10125	COG1114	Component of the transport system for branched-chain amino acids
KM390_10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM390_10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM390_10160	COG1876	peptidase activity
KM390_10170	COG0154	amidase activity
KM390_10175	COG2211	Major facilitator Superfamily
KM390_10195	COG0561	phosphatase activity
KM390_10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM390_10210	COG4106	trans-aconitate 2-methyltransferase activity
KM390_10225	COG1819	glycosyl
KM390_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_10260	COG0456	acetyltransferase
KM390_10310	COG3874	Sporulation protein YtfJ
KM390_10335	COG2226	methyltransferase
KM390_10360	COG0346	lactoylglutathione lyase activity
KM390_10370	COG0604	alcohol dehydrogenase
KM390_10375	COG1595	DNA-templated transcription, initiation
KM390_10400	COG0386	Belongs to the glutathione peroxidase family
KM390_10405	COG1305	Transglutaminase-like
KM390_10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM390_10415	COG0714	Associated with various cellular activities
KM390_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM390_10435	COG1140	nitrate reductase beta subunit
KM390_10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM390_10445	COG2181	nitrate reductase activity
KM390_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM390_10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM390_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM390_10480	COG0303	'Molybdopterin
KM390_10485	COG0314	molybdopterin synthase activity
KM390_10495	COG2223	nitrite transmembrane transporter activity
KM390_10510	COG1648	precorrin-2 dehydrogenase activity
KM390_10520	COG1587	Uroporphyrinogen-III synthase
KM390_10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM390_10525	COG2146	nitrite reductase [NAD(P)H] activity
KM390_10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM390_10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM390_10570	COG2359	stage V sporulation protein S
KM390_10585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM390_10600	COG1418	mRNA catabolic process
KM390_10605	COG0488	(ABC) transporter
KM390_10620	COG0629	single-stranded DNA binding
KM390_10635	COG1413	lyase activity
KM390_10650	COG2136	Putative SAM-dependent methyltransferase
KM390_10650	COG2521	methyltransferase
KM390_10655	COG0018	arginyl-trna synthetase
KM390_10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM390_10700	COG0017	Asparaginyl-tRNA synthetase
KM390_10720	COG1674	ftsk spoiiie
KM390_10790	COG1929	Belongs to the glycerate kinase type-1 family
KM390_10795	COG0471	metal ion transport
KM390_10800	COG0745	RESPONSE REGULATOR receiver
KM390_10805	COG3850	Histidine kinase
KM390_10805	COG5002	protein histidine kinase activity
KM390_10820	COG0733	neurotransmitter:sodium symporter activity
KM390_10845	COG2610	gluconate transmembrane transporter activity
KM390_10850	COG1454	alcohol dehydrogenase
KM390_10855	COG1794	racemase activity, acting on amino acids and derivatives
KM390_10865	COG0456	acetyltransferase
KM390_10880	COG1131	(ABC) transporter
KM390_10895	COG0546	phosphoglycolate phosphatase activity
KM390_10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM390_10930	COG0768	penicillin binding
KM390_10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM390_10940	COG0204	Acyl-transferase
KM390_10945	COG1272	protein, Hemolysin III
KM390_10955	COG0805	protein transport
KM390_10965	COG1307	EDD domain protein, DegV family
KM390_10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM390_10975	COG1999	signal sequence binding
KM390_10980	COG0071	Belongs to the small heat shock protein (HSP20) family
KM390_10985	COG0367	asparagine synthase
KM390_11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM390_11030	COG1051	belongs to the nudix hydrolase family
KM390_11040	COG0668	transmembrane transport
KM390_11045	COG4585	Histidine kinase
KM390_11045	COG2203	Gaf domain
KM390_11050	COG2197	response regulator
KM390_11060	COG1064	alcohol dehydrogenase
KM390_11085	COG1070	Carbohydrate kinase
KM390_11090	COG1070	Carbohydrate kinase
KM390_11120	COG1125	glycine betaine transport
KM390_11120	COG0517	IMP dehydrogenase activity
KM390_11125	COG1174	glycine betaine transport
KM390_11160	COG1253	flavin adenine dinucleotide binding
KM390_11165	COG1012	belongs to the aldehyde dehydrogenase family
KM390_11170	COG5506	Protein of unknown function (DUF1694)
KM390_11185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM390_11190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM390_11195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM390_11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM390_11205	COG0456	acetyltransferase
KM390_11210	COG3829	transcription factor binding
KM390_11215	COG1509	lysine 2,3-aminomutase activity
KM390_11255	COG4326	sporulation control protein
KM390_11260	COG0671	phosphoesterase, PA-phosphatase related
KM390_11265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM390_11270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM390_11300	COG1715	Restriction endonuclease
KM390_11300	COG1787	Restriction endonuclease
KM390_11390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM390_11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM390_11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM390_11435	COG2814	Major facilitator Superfamily
KM390_11440	COG4841	protein insertion into membrane
KM390_11445	COG0372	Belongs to the citrate synthase family
KM390_11450	COG2079	MmgE PrpD family protein
KM390_11455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM390_11460	COG1960	acyl-CoA dehydrogenase activity
KM390_11465	COG2084	Dehydrogenase
KM390_11475	COG1280	lysine exporter protein (LysE YggA)
KM390_11480	COG1024	Enoyl-CoA hydratase
KM390_11495	COG0420	3'-5' exonuclease activity
KM390_11500	COG0419	ATPase involved in DNA repair
KM390_11520	COG2223	nitrite transmembrane transporter activity
KM390_11525	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_11530	COG1169	isochorismate synthase
KM390_11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM390_11540	COG1535	isochorismatase
KM390_11540	COG3433	isochorismatase activity
KM390_11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM390_11550	COG3251	PFAM MbtH domain protein
KM390_11555	COG2814	Major facilitator Superfamily
KM390_11570	COG0776	regulation of translation
KM390_11580	COG2318	DinB family
KM390_11590	COG1115	amino acid carrier protein
KM390_11605	COG2329	Antibiotic biosynthesis monooxygenase
KM390_11610	COG1187	pseudouridine synthase activity
KM390_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM390_11630	COG0596	Alpha beta hydrolase
KM390_11635	COG2814	Major facilitator Superfamily
KM390_11655	COG2226	methyltransferase
KM390_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_11735	COG1247	-acetyltransferase
KM390_11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM390_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_11785	COG1278	Cold shock
KM390_11800	COG0010	Belongs to the arginase family
KM390_11805	COG0561	phosphatase activity
KM390_11850	COG0583	DNA-binding transcription factor activity
KM390_11855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM390_11870	COG0583	DNA-binding transcription factor activity
KM390_11875	COG2258	MOSC domain
KM390_11890	COG1132	(ABC) transporter
KM390_11895	COG1132	(ABC) transporter
KM390_11915	COG1396	sequence-specific DNA binding
KM390_11940	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM390_11945	COG1595	DNA-templated transcription, initiation
KM390_11970	COG1649	PFAM Uncharacterised BCR, COG1649
KM390_11995	COG2971	BadF BadG BcrA BcrD
KM390_12000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM390_12005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM390_12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_12055	COG1309	transcriptional regulator
KM390_12070	COG0577	efflux transmembrane transporter activity
KM390_12070	COG1136	(ABC) transporter
KM390_12075	COG0500	methyltransferase
KM390_12075	COG3615	Tellurite resistance protein tehB
KM390_12085	COG2226	methyltransferase
KM390_12090	COG3961	Belongs to the TPP enzyme family
KM390_12095	COG1846	Transcriptional regulator
KM390_12130	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM390_12145	COG1595	DNA-templated transcription, initiation
KM390_12155	COG0768	penicillin binding
KM390_12165	COG2367	Beta-lactamase
KM390_12170	COG0671	phosphoesterase, PA-phosphatase related
KM390_12175	COG1609	Transcriptional regulator
KM390_12180	COG2814	Major facilitator Superfamily
KM390_12185	COG0673	inositol 2-dehydrogenase activity
KM390_12195	COG1012	belongs to the aldehyde dehydrogenase family
KM390_12210	COG0191	fructose-bisphosphate aldolase activity
KM390_12215	COG3718	enzyme involved in inositol metabolism
KM390_12240	COG0457	Tetratricopeptide repeat
KM390_12245	COG1476	TRANSCRIPTIONal
KM390_12260	COG1876	peptidase activity
KM390_12280	COG1309	transcriptional regulator
KM390_12285	COG0488	(ABC) transporter
KM390_12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_12315	COG1252	NADH dehydrogenase
KM390_12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_12335	COG1131	(ABC) transporter
KM390_12345	COG1309	transcriptional regulator
KM390_12360	COG1960	acyl-CoA dehydrogenase activity
KM390_12365	COG0439	Biotin carboxylase
KM390_12370	COG0511	ligase activity, forming carbon-carbon bonds
KM390_12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM390_12380	COG1024	Enoyl-CoA hydratase
KM390_12385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM390_12390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM390_12400	COG1247	-acetyltransferase
KM390_12405	COG0572	uridine kinase
KM390_12415	COG2318	DinB family
KM390_12420	COG1686	Belongs to the peptidase S11 family
KM390_12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM390_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM390_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM390_12510	COG2814	Major facilitator Superfamily
KM390_12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM390_12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_12565	COG1063	alcohol dehydrogenase
KM390_12595	COG3773	Cell wall hydrolase
KM390_12605	COG0745	RESPONSE REGULATOR receiver
KM390_12620	COG0488	(ABC) transporter
KM390_12635	COG1136	(ABC) transporter
KM390_12660	COG0460	homoserine dehydrogenase
KM390_12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM390_12740	COG2124	cytochrome p450
KM390_12775	COG0561	phosphatase activity
KM390_12785	COG5002	protein histidine kinase activity
KM390_12790	COG0768	penicillin binding
KM390_12795	COG1819	glycosyl
KM390_12800	COG1794	racemase activity, acting on amino acids and derivatives
KM390_12810	COG1122	ATPase activity
KM390_12825	COG2205	protein histidine kinase activity
KM390_12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM390_12840	COG0604	alcohol dehydrogenase
KM390_12845	COG0768	penicillin binding
KM390_12855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM390_12890	COG0693	protein deglycase activity
KM390_12920	COG2814	Major facilitator Superfamily
KM390_12935	COG0584	glycerophosphoryl diester phosphodiesterase
KM390_12955	COG0697	spore germination
KM390_12980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM390_12990	COG2223	nitrite transmembrane transporter activity
KM390_13005	COG2816	NAD+ diphosphatase activity
KM390_13010	COG0592	DNA-directed DNA polymerase activity
KM390_13015	COG1051	belongs to the nudix hydrolase family
KM390_13050	COG3878	Protein conserved in bacteria
KM390_13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM390_13110	COG0322	excinuclease ABC activity
KM390_13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM390_13175	COG1011	Hydrolase
KM390_13195	COG0076	glutamate decarboxylase activity
KM390_13210	COG1523	belongs to the glycosyl hydrolase 13 family
KM390_13215	COG3227	Zinc metalloprotease (Elastase)
KM390_13235	COG0201	protein transport
KM390_13245	COG0697	spore germination
KM390_13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_13280	COG4129	membrane
KM390_13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_13300	COG2959	enzyme of heme biosynthesis
KM390_13320	COG3483	tryptophan 2,3-dioxygenase activity
KM390_13325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM390_13330	COG3844	kynureninase activity
KM390_13335	COG1309	transcriptional regulator
KM390_13365	COG3284	Transcriptional regulator
KM390_13385	COG1349	DNA-binding transcription factor activity
KM390_13405	COG1959	2 iron, 2 sulfur cluster binding
KM390_13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM390_13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM390_13430	COG0022	dehydrogenase e1 component
KM390_13435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM390_13445	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_13450	COG0456	acetyltransferase
KM390_13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM390_13480	COG4176	ABC-type proline glycine betaine transport system permease component
KM390_13485	COG4175	Glycine betaine
KM390_13485	COG0517	IMP dehydrogenase activity
KM390_13510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM390_13515	COG2153	protein acetylation
KM390_13520	COG3397	chitin binding
KM390_13535	COG2205	protein histidine kinase activity
KM390_13560	COG0658	competence protein
KM390_13560	COG2333	competence protein COMEC
KM390_13610	COG3973	AAA domain
KM390_13625	COG2105	PFAM AIG2 family protein
KM390_13630	COG0514	ATP-dependent DNA helicase (RecQ)
KM390_13650	COG4637	Psort location Cytoplasmic, score
KM390_13675	COG3397	chitin binding
KM390_13690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM390_13695	COG1115	amino acid carrier protein
KM390_13700	COG1012	belongs to the aldehyde dehydrogenase family
KM390_13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM390_13715	COG3938	Belongs to the proline racemase family
KM390_13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM390_13760	COG0586	Pfam SNARE associated Golgi protein
KM390_13775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM390_13780	COG0519	Catalyzes the synthesis of GMP from XMP
KM390_13785	COG4166	transmembrane transport
KM390_13795	COG4948	Mandelate Racemase Muconate Lactonizing
KM390_13840	COG2936	dipeptidyl-peptidase activity
KM390_13845	COG5002	protein histidine kinase activity
KM390_13885	COG1164	Oligoendopeptidase f
KM390_13900	COG1307	EDD domain protein, DegV family
KM390_13920	COG2814	Major facilitator Superfamily
KM390_13930	COG1664	Polymer-forming cytoskeletal
KM390_13935	COG0789	Transcriptional regulator
KM390_13940	COG4533	DNA binding
KM390_13945	COG0477	Major facilitator Superfamily
KM390_13945	COG2814	Major facilitator Superfamily
KM390_13965	COG2261	transglycosylase associated protein
KM390_13980	COG2226	methyltransferase
KM390_14015	COG0436	Aminotransferase
KM390_14020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM390_14025	COG5146	pantothenate kinase activity
KM390_14045	COG1131	(ABC) transporter
KM390_14090	COG0628	permease
KM390_14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM390_14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM390_14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM390_14115	COG1116	anion transmembrane transporter activity
KM390_14135	COG2816	NAD+ diphosphatase activity
KM390_14155	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM390_14180	COG0697	spore germination
KM390_14185	COG2318	DinB family
KM390_14205	COG4912	Dna alkylation repair
KM390_14225	COG0861	Integral membrane protein TerC family
KM390_14230	COG1368	sulfuric ester hydrolase activity
KM390_14235	COG0488	(ABC) transporter
KM390_14245	COG1033	growth of symbiont in host cell
KM390_14245	COG2409	Drug exporters of the RND superfamily
KM390_14250	COG1033	growth of symbiont in host cell
KM390_14250	COG2409	Drug exporters of the RND superfamily
KM390_14255	COG1033	growth of symbiont in host cell
KM390_14255	COG2409	Drug exporters of the RND superfamily
KM390_14260	COG1309	transcriptional regulator
KM390_14275	COG0287	Prephenate dehydrogenase
KM390_14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM390_14285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM390_14290	COG1605	Chorismate mutase
KM390_14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM390_14325	COG3584	3D domain protein
KM390_14325	COG1388	LysM domain
KM390_14335	COG1595	DNA-templated transcription, initiation
KM390_14360	COG1879	ABC-type sugar transport system periplasmic component
KM390_14370	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM390_14380	COG2390	Transcriptional regulator
KM390_14415	COG2329	Antibiotic biosynthesis monooxygenase
KM390_14435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_14445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM390_14450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM390_14455	COG4187	Peptidase family M20/M25/M40
KM390_14460	COG1414	Transcriptional regulator
KM390_14465	COG0833	amino acid
KM390_14470	COG1690	Belongs to the RtcB family
KM390_14475	COG3239	Fatty acid desaturase
KM390_14480	COG1785	Belongs to the alkaline phosphatase family
KM390_14490	COG3655	Transcriptional regulator
KM390_14505	COG4377	Putative membrane peptidase family (DUF2324)
KM390_14515	COG3279	Response regulator of the LytR AlgR family
KM390_14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_14530	COG0346	lactoylglutathione lyase activity
KM390_14550	COG0714	Associated with various cellular activities
KM390_14575	COG0463	Glycosyl transferase, family 2
KM390_14600	COG0463	Glycosyl transferase, family 2
KM390_14610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM390_14615	COG0753	catalase activity
KM390_14625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM390_14650	COG0714	Associated with various cellular activities
KM390_14660	COG0778	Nitroreductase
KM390_14665	COG1846	Transcriptional regulator
KM390_14700	COG1725	Transcriptional regulator
KM390_14710	COG0577	efflux transmembrane transporter activity
KM390_14710	COG1136	(ABC) transporter
KM390_14735	COG2207	Transcriptional regulator
KM390_14740	COG0456	acetyltransferase
KM390_14760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_14780	COG0642	Histidine kinase
KM390_14785	COG0745	RESPONSE REGULATOR receiver
KM390_14790	COG0596	Alpha beta hydrolase
KM390_14820	COG0730	response to heat
KM390_14830	COG0833	amino acid
KM390_14840	COG4335	DNA alkylation repair
KM390_14880	COG0768	penicillin binding
KM390_14890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM390_14920	COG1984	allophanate hydrolase subunit 2
KM390_14925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM390_14930	COG1414	Transcriptional regulator
KM390_14945	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM390_14950	COG0640	Transcriptional regulator
KM390_14960	COG1960	acyl-CoA dehydrogenase activity
KM390_14975	COG3314	Sporulation integral membrane protein YlbJ
KM390_14990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM390_15005	COG0574	Belongs to the PEP-utilizing enzyme family
KM390_15005	COG3848	Pyruvate phosphate dikinase
KM390_15010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_15025	COG5577	PFAM Coat F domain
KM390_15030	COG3403	YqcI/YcgG family
KM390_15035	COG1280	lysine exporter protein (LysE YggA)
KM390_15070	COG1063	alcohol dehydrogenase
KM390_15085	COG1027	Aspartate ammonia-lyase
KM390_15090	COG0252	asparaginase activity
KM390_15095	COG1396	sequence-specific DNA binding
KM390_15105	COG0322	excinuclease ABC activity
KM390_15110	COG0531	amino acid
KM390_15115	COG1114	Component of the transport system for branched-chain amino acids
KM390_15120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM390_15130	COG0281	malic enzyme
KM390_15145	COG0531	amino acid
KM390_15155	COG0784	Response regulator, receiver
KM390_15165	COG2066	Belongs to the glutaminase family
KM390_15170	COG1115	amino acid carrier protein
KM390_15200	COG0737	Belongs to the 5'-nucleotidase family
KM390_15205	COG0753	catalase activity
KM390_15210	COG2267	carboxylic ester hydrolase activity
KM390_15215	COG1335	isochorismatase
KM390_15235	COG0583	DNA-binding transcription factor activity
KM390_15240	COG1846	Transcriptional regulator
KM390_15280	COG0415	Belongs to the DNA photolyase family
KM390_15285	COG0288	reversible hydration of carbon dioxide
KM390_15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM390_15300	COG5609	conserved protein (DUF2294)
KM390_15315	COG1575	Belongs to the MenA family. Type 1 subfamily
KM390_15320	COG2267	carboxylic ester hydrolase activity
KM390_15325	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM390_15330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM390_15335	COG1121	(ABC) transporter
KM390_15365	COG0798	PFAM Bile acid sodium symporter
KM390_15370	COG0346	lactoylglutathione lyase activity
KM390_15375	COG0640	Transcriptional regulator
KM390_15390	COG0443	Heat shock 70 kDa protein
KM390_15405	COG1522	sequence-specific DNA binding
KM390_15420	COG0346	lactoylglutathione lyase activity
KM390_15445	COG2169	Transcriptional regulator
KM390_15490	COG2814	Major facilitator Superfamily
KM390_15515	COG0745	RESPONSE REGULATOR receiver
KM390_15520	COG3850	Histidine kinase
KM390_15520	COG5002	protein histidine kinase activity
KM390_15545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM390_15565	COG1476	TRANSCRIPTIONal
KM390_15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_15585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM390_15595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_15600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM390_15615	COG1136	(ABC) transporter
KM390_15620	COG0577	efflux transmembrane transporter activity
KM390_15635	COG3850	Histidine kinase
KM390_15635	COG5002	protein histidine kinase activity
KM390_15645	COG2364	Membrane
KM390_15650	COG1846	Transcriptional regulator
KM390_15660	COG2808	Putative FMN-binding domain
KM390_15665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_15670	COG2271	Major facilitator Superfamily
KM390_15675	COG1556	Lactate utilization protein
KM390_15680	COG1139	Iron-sulfur cluster binding protein
KM390_15690	COG0583	DNA-binding transcription factor activity
KM390_15700	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM390_15720	COG0738	Major facilitator superfamily
KM390_15725	COG0673	inositol 2-dehydrogenase activity
KM390_15730	COG0561	phosphatase activity
KM390_15740	COG1609	Transcriptional regulator
KM390_15745	COG0457	Tetratricopeptide repeat
KM390_15765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM390_15795	COG0534	Mate efflux family protein
KM390_15815	COG2814	Major facilitator Superfamily
KM390_15820	COG1309	transcriptional regulator
KM390_15835	COG0814	amino acid
KM390_15840	COG1760	l-serine dehydratase
KM390_15845	COG1760	l-serine dehydratase
KM390_15855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM390_15860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM390_15870	COG1335	isochorismatase
KM390_15875	COG1522	sequence-specific DNA binding
KM390_15880	COG0531	amino acid
KM390_15895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM390_15915	COG1595	DNA-templated transcription, initiation
KM390_15930	COG0662	Cupin 2, conserved barrel domain protein
KM390_15935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_15935	COG2207	Transcriptional regulator
KM390_15985	COG0477	Major facilitator Superfamily
KM390_15995	COG1846	Transcriptional regulator
KM390_16000	COG2814	Major facilitator Superfamily
KM390_16010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM390_16015	COG1131	(ABC) transporter
KM390_16035	COG2076	Multidrug Resistance protein
KM390_16040	COG1309	transcriptional regulator
KM390_16050	COG2031	fatty acid transporter
KM390_16060	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM390_16090	COG1122	ATPase activity
KM390_16095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM390_16110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM390_16115	COG1288	antiporter activity
KM390_16120	COG2356	endonuclease I
KM390_16135	COG3620	sequence-specific DNA binding
KM390_16140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM390_16145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM390_16150	COG0124	histidyl-tRNA synthetase
KM390_16165	COG1733	regulation of RNA biosynthetic process
KM390_16170	COG0778	Nitroreductase
KM390_16190	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_16200	COG1131	(ABC) transporter
KM390_16225	COG1011	Hydrolase
KM390_16235	COG2365	Tyrosine phosphatase family
KM390_16260	COG0346	lactoylglutathione lyase activity
KM390_16265	COG1940	carbohydrate kinase activity
KM390_16270	COG0738	Major facilitator superfamily
KM390_16275	COG0110	maltose O-acetyltransferase activity
KM390_16285	COG0577	efflux transmembrane transporter activity
KM390_16285	COG1136	(ABC) transporter
KM390_16300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM390_16305	COG0628	permease
KM390_16325	COG2226	methyltransferase
KM390_16335	COG0477	Major facilitator Superfamily
KM390_16365	COG1253	flavin adenine dinucleotide binding
KM390_16370	COG0789	Transcriptional regulator
KM390_16375	COG0697	spore germination
KM390_16380	COG1357	PFAM Pentapeptide repeats (8 copies)
KM390_16385	COG3813	Protein conserved in bacteria
KM390_16390	COG2706	6-phosphogluconolactonase activity
KM390_16395	COG1070	Carbohydrate kinase
KM390_16405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM390_16410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM390_16420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM390_16425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM390_16430	COG0604	alcohol dehydrogenase
KM390_16435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM390_16445	COG0604	alcohol dehydrogenase
KM390_16445	COG3321	synthase
KM390_16450	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_16475	COG0656	L-ascorbic acid biosynthetic process
KM390_16480	COG2814	Major facilitator Superfamily
KM390_16495	COG0346	lactoylglutathione lyase activity
KM390_16500	COG0814	amino acid
KM390_16525	COG1393	Belongs to the ArsC family
KM390_16530	COG1733	regulation of RNA biosynthetic process
KM390_16535	COG2188	Transcriptional regulator
KM390_16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM390_16550	COG1733	regulation of RNA biosynthetic process
KM390_16555	COG1733	regulation of RNA biosynthetic process
KM390_16570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_16590	COG0384	phenazine biosynthesis protein PhzF
KM390_16600	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_16610	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_16620	COG1733	regulation of RNA biosynthetic process
KM390_16655	COG1191	sigma factor activity
KM390_16670	COG1309	transcriptional regulator
KM390_16690	COG3152	Membrane
KM390_16715	COG1151	hydroxylamine reductase activity
KM390_16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_16730	COG3409	Peptidoglycan-binding domain 1 protein
KM390_16730	COG3757	hydrolase, family 25
KM390_16765	COG2072	flavoprotein involved in K transport
KM390_16800	COG0604	alcohol dehydrogenase
KM390_16805	COG1113	amino acid transport
KM390_16810	COG2814	Major facilitator Superfamily
KM390_16840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM390_16845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM390_16865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_16880	COG3739	integral membrane protein
KM390_16885	COG0384	phenazine biosynthesis protein PhzF
KM390_16915	COG0583	DNA-binding transcription factor activity
KM390_16935	COG1193	negative regulation of DNA recombination
KM390_16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM390_16990	COG0584	glycerophosphoryl diester phosphodiesterase
KM390_17015	COG0640	Transcriptional regulator
KM390_17020	COG0604	alcohol dehydrogenase
KM390_17040	COG2808	Putative FMN-binding domain
KM390_17045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM390_17055	COG0385	Bile acid
KM390_17060	COG0277	FAD linked oxidase domain protein
KM390_17090	COG1216	Glycosyl transferase, family 2
KM390_17095	COG1024	Enoyl-CoA hydratase
KM390_17105	COG1285	pathogenesis
KM390_17120	COG2514	catechol 2,3-dioxygenase activity
KM390_17125	COG2720	vancomycin resistance protein
KM390_17165	COG0716	FMN binding
KM390_17195	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_17205	COG0165	Argininosuccinate lyase
KM390_17220	COG4145	pantothenate transmembrane transporter activity
KM390_17230	COG1012	belongs to the aldehyde dehydrogenase family
KM390_17235	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_17245	COG1657	PFAM Prenyltransferase squalene oxidase
KM390_17250	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM390_17255	COG2962	Rard protein
KM390_17260	COG3326	Membrane
KM390_17275	COG0489	protein tyrosine kinase activity
KM390_17285	COG0314	molybdopterin synthase activity
KM390_17290	COG0303	'Molybdopterin
KM390_17295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM390_17300	COG2116	formate transmembrane transporter activity
KM390_17310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM390_17315	COG5609	conserved protein (DUF2294)
KM390_17320	COG2427	Protein of unknown function (DUF1641)
KM390_17325	COG3383	formate dehydrogenase (NAD+) activity
KM390_17330	COG0697	spore germination
KM390_17370	COG2226	methyltransferase
KM390_17375	COG4166	transmembrane transport
KM390_17380	COG4166	transmembrane transport
KM390_17385	COG4166	transmembrane transport
KM390_17390	COG1301	dicarboxylic acid transport
KM390_17395	COG1316	TRANSCRIPTIONal
KM390_17425	COG1131	(ABC) transporter
KM390_17435	COG0673	inositol 2-dehydrogenase activity
KM390_17440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM390_17445	COG0187	DNA topoisomerase II activity
KM390_17450	COG1832	CoA-binding protein
KM390_17455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM390_17460	COG0745	RESPONSE REGULATOR receiver
KM390_17475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM390_17480	COG4841	protein insertion into membrane
KM390_17485	COG0824	Thioesterase
KM390_17515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM390_17525	COG2274	protein secretion by the type I secretion system
KM390_17530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM390_17570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM390_17585	COG0183	Belongs to the thiolase family
KM390_17590	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_17595	COG1268	BioY protein
KM390_17600	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_17650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_17660	COG5002	protein histidine kinase activity
KM390_17665	COG0400	carboxylic ester hydrolase activity
KM390_17670	COG0346	lactoylglutathione lyase activity
KM390_17675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM390_17680	COG0069	glutamate synthase activity
KM390_17685	COG1902	pentaerythritol trinitrate reductase activity
KM390_17690	COG1329	Transcriptional regulator
KM390_17695	COG0010	Belongs to the arginase family
KM390_17720	COG2226	methyltransferase
KM390_17775	COG4846	Membrane protein involved in cytochrome C biogenesis
KM390_17780	COG0785	Cytochrome C biogenesis protein
KM390_17790	COG0583	DNA-binding transcription factor activity
KM390_17795	COG1380	Effector of murein hydrolase LrgA
KM390_17800	COG1346	cytolysis
KM390_17825	COG3409	Peptidoglycan-binding domain 1 protein
KM390_17825	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM390_17840	COG1132	(ABC) transporter
KM390_17845	COG1132	(ABC) transporter
KM390_17875	COG3639	organic phosphonate transmembrane transporter activity
KM390_17880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM390_17900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM390_17920	COG1695	Transcriptional regulator
KM390_17955	COG3409	Peptidoglycan-binding domain 1 protein
KM390_17955	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM390_17955	COG1388	LysM domain
KM390_17960	COG4824	toxin secretion phage lysis holin
KM390_18115	COG1595	DNA-templated transcription, initiation
KM390_18160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM390_18240	COG1396	sequence-specific DNA binding
KM390_18265	COG0174	glutamine synthetase
KM390_18270	COG0789	Transcriptional regulator
KM390_18275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM390_18285	COG2860	membrane
KM390_18295	COG0464	growth
KM390_18325	COG3584	3D domain protein
KM390_18325	COG1388	LysM domain
KM390_18330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM390_18330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM390_18330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM390_18335	COG1105	Belongs to the carbohydrate kinase PfkB family
KM390_18340	COG1349	DNA-binding transcription factor activity
KM390_18350	COG2322	membrane
KM390_18360	COG1113	amino acid transport
KM390_18375	COG1408	metallophosphoesterase
KM390_18380	COG2116	formate transmembrane transporter activity
KM390_18390	COG2217	Heavy metal translocating P-type atpase
KM390_18395	COG2608	mercury ion transmembrane transporter activity
KM390_18400	COG1937	Protein conserved in bacteria
KM390_18410	COG2819	hydrolase of the alpha beta superfamily
KM390_18415	COG1120	ATPase activity
KM390_18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_18435	COG0708	Exodeoxyribonuclease III
KM390_18440	COG2169	Transcriptional regulator
KM390_18445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM390_18450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM390_18460	COG2364	Membrane
KM390_18475	COG2267	carboxylic ester hydrolase activity
KM390_18480	COG0346	lactoylglutathione lyase activity
KM390_18485	COG5001	Diguanylate cyclase
KM390_18485	COG3300	MHYT domain
KM390_18500	COG1346	cytolysis
KM390_18505	COG1380	Effector of murein hydrolase LrgA
KM390_18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM390_18515	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM390_18515	COG0596	Alpha beta hydrolase
KM390_18520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM390_18540	COG1404	Belongs to the peptidase S8 family
KM390_18545	COG3773	Cell wall hydrolase
KM390_18550	COG0562	UDP-galactopyranose mutase
KM390_18555	COG1368	sulfuric ester hydrolase activity
KM390_18560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM390_18570	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM390_18595	COG1131	(ABC) transporter
KM390_18615	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM390_18620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM390_18625	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM390_18630	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM390_18630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM390_18640	COG2359	stage V sporulation protein S
KM390_18645	COG1692	metallophosphoesterase
KM390_18670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM390_18675	COG1426	Protein conserved in bacteria
KM390_18690	COG0300	oxidoreductase activity
KM390_18695	COG0612	Peptidase, M16
KM390_18700	COG0612	Peptidase, M16
KM390_18705	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM390_18715	COG3845	ABC transporter
KM390_18720	COG1744	ABC transporter substrate-binding protein PnrA-like
KM390_18725	COG2188	Transcriptional regulator
KM390_18730	COG1674	ftsk spoiiie
KM390_18740	COG0740	serine-type endopeptidase activity
KM390_18745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM390_18755	COG0527	aspartate kinase activity
KM390_18760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM390_18765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM390_18770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM390_18775	COG1873	PFAM PRC-barrel domain
KM390_18780	COG0612	Peptidase, M16
KM390_18785	COG0726	polysaccharide deacetylase
KM390_18800	COG0196	riboflavin kinase activity
KM390_18805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM390_18815	COG1550	Protein conserved in bacteria
KM390_18825	COG1358	cellular component organization or biogenesis
KM390_18830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM390_18835	COG0195	Participates in both transcription termination and antitermination
KM390_18855	COG0750	zinc metalloprotease
KM390_18865	COG4589	Belongs to the CDS family
KM390_18870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM390_18880	COG0528	UMP kinase activity
KM390_18910	COG4974	Belongs to the 'phage' integrase family
KM390_18920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM390_18930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM390_18970	COG1837	Belongs to the UPF0109 family
KM390_18980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM390_18990	COG0552	protein localization to endoplasmic reticulum
KM390_18995	COG1196	nuclear chromosome segregation
KM390_19005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM390_19010	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_19015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM390_19030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM390_19035	COG1461	Dihydroxyacetone kinase
KM390_19040	COG1302	Protein conserved in bacteria
KM390_19055	COG1564	THIamine pyrophosphokinase
KM390_19060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM390_19065	COG1162	GTPase activity
KM390_19070	COG0515	serine threonine protein kinase
KM390_19070	COG2815	serine threonine protein kinase
KM390_19075	COG0631	protein serine/threonine phosphatase activity
KM390_19085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM390_19085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM390_19095	COG0242	peptide deformylase activity
KM390_19100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM390_19105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM390_19125	COG1561	YicC-like family, N-terminal region
KM390_19130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM390_19140	COG0006	proline dipeptidase activity
KM390_19155	COG3069	C4-dicarboxylate transmembrane transporter activity
KM390_19220	COG0564	pseudouridine synthase activity
KM390_19240	COG3599	regulation of cell shape
KM390_19245	COG2302	S4 RNA-binding domain
KM390_19250	COG0762	integral membrane protein
KM390_19260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM390_19265	COG1496	oxidoreductase activity
KM390_19270	COG1873	PFAM PRC-barrel domain
KM390_19275	COG1191	sigma factor activity
KM390_19280	COG1191	sigma factor activity
KM390_19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM390_19295	COG0849	cell division
KM390_19300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM390_19305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM390_19315	COG0772	Belongs to the SEDS family
KM390_19330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM390_19335	COG0768	penicillin binding
KM390_19340	COG0768	penicillin binding
KM390_19345	COG4839	cell division protein FtsL
KM390_19360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM390_19375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM390_19380	COG1399	metal-binding, possibly nucleic acid-binding protein
KM390_19430	COG4824	toxin secretion phage lysis holin
KM390_19515	COG4626	Terminase
KM390_19515	COG1802	Transcriptional regulator
KM390_19540	COG0582	viral genome integration into host DNA
KM390_19605	COG0756	dUTP diphosphatase activity
KM390_19620	COG1191	sigma factor activity
KM390_19645	COG1484	DNA-dependent DNA replication
KM390_19675	COG1396	sequence-specific DNA binding
KM390_19690	COG1396	sequence-specific DNA binding
KM390_19705	COG0582	viral genome integration into host DNA
KM390_19715	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM390_19720	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM390_19725	COG3314	Sporulation integral membrane protein YlbJ
KM390_19735	COG0742	ribosomal rna small subunit methyltransferase
KM390_19750	COG3679	Belongs to the UPF0342 family
KM390_19755	COG0406	alpha-ribazole phosphatase activity
KM390_19770	COG2340	Cysteine-rich secretory protein family
KM390_19785	COG3336	cytochrome c oxidase
KM390_19820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM390_19825	COG0772	Belongs to the SEDS family
KM390_19835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM390_19840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM390_19850	COG4896	Protein conserved in bacteria
KM390_19865	COG1217	gtp-binding protein TYPA
KM390_19875	COG0483	inositol monophosphate 1-phosphatase activity
KM390_19895	COG1982	Orn Lys Arg decarboxylase major
KM390_19940	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM390_19945	COG0022	dehydrogenase e1 component
KM390_19950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM390_19960	COG0242	peptide deformylase activity
KM390_19965	COG0561	phosphatase activity
KM390_19975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM390_19980	COG0569	domain protein
KM390_20000	COG0583	DNA-binding transcription factor activity
KM390_20005	COG0517	IMP dehydrogenase activity
KM390_20015	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM390_20025	COG4703	Protein of unknown function (DUF1797)
KM390_20040	COG2200	EAL domain
KM390_20045	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_20050	COG1408	metallophosphoesterase
KM390_20060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM390_20095	COG2814	Major facilitator Superfamily
KM390_20115	COG3209	COG3209 Rhs family protein
KM390_20125	COG2205	protein histidine kinase activity
KM390_20135	COG0436	Aminotransferase
KM390_20140	COG1609	Transcriptional regulator
KM390_20145	COG3833	ABC-type maltose transport systems, permease component
KM390_20150	COG1175	transmembrane transport
KM390_20155	COG2182	Extracellular solute-binding protein
KM390_20165	COG0366	Alpha amylase catalytic
KM390_20170	COG3842	ATPase activity
KM390_20210	COG0183	Belongs to the thiolase family
KM390_20245	COG1695	Transcriptional regulator
KM390_20250	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_20260	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM390_20270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM390_20275	COG0436	Aminotransferase
KM390_20295	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM390_20315	COG2199	diguanylate cyclase activity
KM390_20320	COG0778	Nitroreductase
KM390_20345	COG2190	(PTS) system
KM390_20345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM390_20345	COG1263	PTS System
KM390_20350	COG3711	transcriptional antiterminator
KM390_20360	COG2188	Transcriptional regulator
KM390_20370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM390_20395	COG1547	Domain of unknown function (DUF309)
KM390_20400	COG0456	acetyltransferase
KM390_20405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM390_20410	COG4086	secreted protein
KM390_20415	COG0561	phosphatase activity
KM390_20420	COG0697	spore germination
KM390_20435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_20460	COG0733	neurotransmitter:sodium symporter activity
KM390_20480	COG1686	Belongs to the peptidase S11 family
KM390_20485	COG1725	Transcriptional regulator
KM390_20490	COG1131	(ABC) transporter
KM390_20505	COG1846	Transcriptional regulator
KM390_20520	COG0598	Magnesium transport protein CorA
KM390_20545	COG4974	Belongs to the 'phage' integrase family
KM390_20555	COG0735	belongs to the Fur family
KM390_20560	COG1300	Membrane
KM390_20580	COG0667	Aldo Keto reductase
KM390_20585	COG0656	L-ascorbic acid biosynthetic process
KM390_20590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM390_20590	COG0456	acetyltransferase
KM390_20600	COG1525	nuclease
KM390_20600	COG4085	toxin activity
KM390_20600	COG0737	Belongs to the 5'-nucleotidase family
KM390_20610	COG0596	Alpha beta hydrolase
KM390_20615	COG2056	Na+-H+ antiporter family
KM390_20620	COG1609	Transcriptional regulator
KM390_20625	COG0456	acetyltransferase
KM390_20630	COG1073	alpha beta
KM390_20645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM390_20645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM390_20650	COG0307	riboflavin synthase, alpha
KM390_20675	COG4106	trans-aconitate 2-methyltransferase activity
KM390_20680	COG1073	alpha beta
KM390_20680	COG2226	methyltransferase
KM390_20695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM390_20705	COG1757	Na H antiporter
KM390_20710	COG0737	Belongs to the 5'-nucleotidase family
KM390_20720	COG1522	sequence-specific DNA binding
KM390_20740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM390_20750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM390_20765	COG0300	oxidoreductase activity
KM390_20775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM390_20780	COG1760	l-serine dehydratase
KM390_20785	COG1760	l-serine dehydratase
KM390_20805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM390_20815	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM390_20820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_20835	COG1376	ErfK ybiS ycfS ynhG family protein
KM390_20840	COG4129	membrane
KM390_20845	COG1126	abc transporter atp-binding protein
KM390_20850	COG0765	amino acid transport
KM390_20855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM390_20875	COG0772	Belongs to the SEDS family
KM390_20880	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM390_20885	COG0022	dehydrogenase e1 component
KM390_20890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM390_20895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM390_20910	COG0280	phosphate acetyltransferase
KM390_20915	COG3829	transcription factor binding
KM390_20915	COG3290	protein histidine kinase activity
KM390_20925	COG0584	glycerophosphoryl diester phosphodiesterase
KM390_20930	COG3093	addiction module antidote protein HigA
KM390_20940	COG0745	RESPONSE REGULATOR receiver
KM390_20945	COG0750	zinc metalloprotease
KM390_20950	COG0497	DNA recombination
KM390_20960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM390_20970	COG0142	geranyltranstransferase activity
KM390_20995	COG1302	Protein conserved in bacteria
KM390_21000	COG0439	Biotin carboxylase
KM390_21005	COG0511	ligase activity, forming carbon-carbon bonds
KM390_21050	COG3854	ATPases associated with a variety of cellular activities
KM390_21075	COG0006	proline dipeptidase activity
KM390_21090	COG3872	metal-dependent enzyme
KM390_21100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM390_21120	COG0095	Lipoate-protein ligase
KM390_21125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_21130	COG1609	Transcriptional regulator
KM390_21140	COG2076	Multidrug Resistance protein
KM390_21145	COG2076	Multidrug Resistance protein
KM390_21180	COG1131	(ABC) transporter
KM390_21185	COG1725	Transcriptional regulator
KM390_21215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM390_21270	COG4970	Tfp pilus assembly protein FimT
KM390_21280	COG1459	type II secretion system
KM390_21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM390_21335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM390_21340	COG0646	methionine synthase
KM390_21340	COG1410	methionine synthase
KM390_21345	COG0646	methionine synthase
KM390_21345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM390_21350	COG0626	cystathionine gamma-synthase activity
KM390_21355	COG0626	cystathionine gamma-synthase activity
KM390_21375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_21385	COG1940	carbohydrate kinase activity
KM390_21390	COG4483	Protein conserved in bacteria
KM390_21395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM390_21400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM390_21405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM390_21410	COG0704	Plays a role in the regulation of phosphate uptake
KM390_21420	COG0581	inorganic phosphate transmembrane transporter activity
KM390_21425	COG0573	inorganic phosphate transmembrane transporter activity
KM390_21430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM390_21435	COG0768	penicillin binding
KM390_21440	COG0477	Major facilitator Superfamily
KM390_21445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM390_21470	COG0735	belongs to the Fur family
KM390_21475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM390_21480	COG1121	(ABC) transporter
KM390_21485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_21515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM390_21520	COG2384	SAM-dependent methyltransferase
KM390_21525	COG2010	Cytochrome c
KM390_21530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM390_21535	COG0358	DNA primase activity
KM390_21545	COG0517	IMP dehydrogenase activity
KM390_21560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM390_21565	COG0295	cytidine deaminase activity
KM390_21570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM390_21580	COG1480	7TM receptor with intracellular HD hydrolase
KM390_21585	COG1702	phosphate starvation-inducible protein PhoH
KM390_21600	COG1610	YqeY-like protein
KM390_21605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM390_21610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM390_21615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM390_21645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM390_21650	COG1733	regulation of RNA biosynthetic process
KM390_21675	COG1466	dna polymerase III delta subunit
KM390_21685	COG2333	competence protein COMEC
KM390_21685	COG0658	competence protein
KM390_21690	COG2131	deaminase
KM390_21695	COG1596	polysaccharide export
KM390_21695	COG1555	photosystem II stabilization
KM390_21700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM390_21705	COG2226	methyltransferase
KM390_21710	COG0799	negative regulation of ribosome biogenesis
KM390_21715	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM390_21725	COG1534	Rna-binding protein
KM390_21735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM390_21740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM390_21765	COG1595	DNA-templated transcription, initiation
KM390_21775	COG0778	Nitroreductase
KM390_21780	COG2357	RelA SpoT domain protein
KM390_21790	COG1785	Belongs to the alkaline phosphatase family
KM390_21800	COG2267	carboxylic ester hydrolase activity
KM390_21835	COG1404	Belongs to the peptidase S8 family
KM390_21840	COG3186	Phenylalanine-4-hydroxylase
KM390_21855	COG2259	Doxx family
KM390_21895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_21905	COG1454	alcohol dehydrogenase
KM390_21905	COG1012	belongs to the aldehyde dehydrogenase family
KM390_21910	COG0626	cystathionine gamma-synthase activity
KM390_21915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM390_21940	COG0768	penicillin binding
KM390_21955	COG0826	peptidase U32
KM390_21960	COG0826	peptidase U32
KM390_21965	COG4122	O-methyltransferase activity
KM390_21970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM390_21990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM390_22000	COG0628	permease
KM390_22020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM390_22030	COG0482	sulfurtransferase activity
KM390_22035	COG1104	cysteine desulfurase activity
KM390_22040	COG1959	2 iron, 2 sulfur cluster binding
KM390_22045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM390_22055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM390_22080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM390_22090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM390_22090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM390_22095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM390_22100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM390_22100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM390_22110	COG2244	polysaccharide biosynthetic process
KM390_22115	COG2323	membrane
KM390_22125	COG1862	Preprotein translocase
KM390_22155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM390_22165	COG0697	spore germination
KM390_22175	COG0640	Transcriptional regulator
KM390_22200	COG0157	Belongs to the NadC ModD family
KM390_22205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM390_22210	COG1104	cysteine desulfurase activity
KM390_22215	COG1827	regulation of RNA biosynthetic process
KM390_22220	COG2258	MOSC domain
KM390_22225	COG0077	Prephenate dehydratase
KM390_22230	COG0577	efflux transmembrane transporter activity
KM390_22235	COG0577	efflux transmembrane transporter activity
KM390_22240	COG1136	(ABC) transporter
KM390_22250	COG0745	RESPONSE REGULATOR receiver
KM390_22255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM390_22260	COG3290	protein histidine kinase activity
KM390_22270	COG2868	ribosomal protein
KM390_22280	COG1530	ribonuclease E activity
KM390_22285	COG1994	Peptidase M50
KM390_22290	COG0739	heme binding
KM390_22295	COG2894	cell division
KM390_22315	COG1077	Cell shape determining protein MreB Mrl
KM390_22335	COG0285	dihydrofolate synthase activity
KM390_22340	COG0525	valine-tRNA ligase activity
KM390_22350	COG1388	LysM domain
KM390_22360	COG0113	porphobilinogen synthase activity
KM390_22365	COG1587	Uroporphyrinogen-III synthase
KM390_22375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM390_22385	COG1846	Transcriptional regulator
KM390_22390	COG1764	response to oxidative stress
KM390_22405	COG0470	DNA polymerase III
KM390_22405	COG1067	ATP-dependent peptidase activity
KM390_22450	COG0622	Phosphoesterase
KM390_22465	COG5401	PFAM Sporulation and spore germination
KM390_22485	COG1309	transcriptional regulator
KM390_22500	COG2197	response regulator
KM390_22505	COG2233	PERMEase
KM390_22515	COG0402	S-adenosylhomocysteine deaminase activity
KM390_22520	COG0402	S-adenosylhomocysteine deaminase activity
KM390_22530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM390_22540	COG0444	Belongs to the ABC transporter superfamily
KM390_22545	COG4608	Belongs to the ABC transporter superfamily
KM390_22550	COG3275	phosphorelay sensor kinase activity
KM390_22555	COG3279	Response regulator of the LytR AlgR family
KM390_22570	COG1983	PspC domain protein
KM390_22575	COG1396	sequence-specific DNA binding
KM390_22580	COG0697	spore germination
KM390_22590	COG1959	2 iron, 2 sulfur cluster binding
KM390_22595	COG1668	transmembrane transport
KM390_22600	COG4152	abc transporter atp-binding protein
KM390_22605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM390_22615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM390_22620	COG1876	peptidase activity
KM390_22625	COG0824	Thioesterase
KM390_22630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM390_22635	COG1053	succinate dehydrogenase
KM390_22640	COG2009	succinate dehydrogenase
KM390_22645	COG1719	4-vinyl reductase, 4VR
KM390_22655	COG3118	belongs to the thioredoxin family
KM390_22660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM390_22665	COG2086	electron transfer activity
KM390_22670	COG1024	Enoyl-CoA hydratase
KM390_22675	COG1309	transcriptional regulator
KM390_22680	COG0318	PFAM AMP-dependent synthetase and ligase
KM390_22700	COG2318	DinB family
KM390_22730	COG1131	(ABC) transporter
KM390_22735	COG2205	protein histidine kinase activity
KM390_22740	COG0745	RESPONSE REGULATOR receiver
KM390_22750	COG4895	conserved protein (DUF2196)
KM390_22755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM390_22770	COG4509	Sortase family
KM390_22775	COG1120	ATPase activity
KM390_22790	COG5386	Cell surface protein
KM390_22800	COG5386	Cell surface protein
KM390_22805	COG1114	Component of the transport system for branched-chain amino acids
KM390_22810	COG1187	pseudouridine synthase activity
KM390_22820	COG1796	DNA polymerase
KM390_22820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM390_22825	COG1286	toxin biosynthetic process
KM390_22870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM390_22880	COG1418	mRNA catabolic process
KM390_22905	COG2814	Major facilitator Superfamily
KM390_22910	COG1566	PFAM secretion protein HlyD family protein
KM390_22915	COG1309	transcriptional regulator
KM390_22920	COG1363	Peptidase, m42
KM390_22945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM390_22955	COG1484	DNA-dependent DNA replication
KM390_22960	COG3611	Membrane attachment protein
KM390_22970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM390_22975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM390_22980	COG0237	dephospho-CoA kinase activity
KM390_22985	COG1971	Probably functions as a manganese efflux pump
KM390_22995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM390_22995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM390_23000	COG5002	protein histidine kinase activity
KM390_23005	COG0745	RESPONSE REGULATOR receiver
KM390_23025	COG0538	isocitrate dehydrogenase activity
KM390_23030	COG0372	Belongs to the citrate synthase family
KM390_23040	COG0628	permease
KM390_23045	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM390_23070	COG1725	Transcriptional regulator
KM390_23075	COG0281	malic enzyme
KM390_23080	COG0587	DNA-directed DNA polymerase activity
KM390_23095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM390_23115	COG4109	DRTGG domain
KM390_23130	COG0006	proline dipeptidase activity
KM390_23165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_23170	COG0662	Cupin 2, conserved barrel domain protein
KM390_23180	COG1476	TRANSCRIPTIONal
KM390_23195	COG1028	Short-chain dehydrogenase reductase Sdr
KM390_23200	COG0589	response to stress
KM390_23240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_23260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM390_23265	COG0827	DNA restriction-modification system
KM390_23270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM390_23275	COG3874	Sporulation protein YtfJ
KM390_23290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM390_23300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM390_23315	COG1104	cysteine desulfurase activity
KM390_23325	COG0583	DNA-binding transcription factor activity
KM390_23330	COG0697	spore germination
KM390_23340	COG1956	GAF domain-containing protein
KM390_23345	COG0626	cystathionine gamma-synthase activity
KM390_23375	COG1595	DNA-templated transcription, initiation
KM390_23385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM390_23390	COG0454	-acetyltransferase
KM390_23395	COG0517	IMP dehydrogenase activity
KM390_23400	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM390_23410	COG0745	RESPONSE REGULATOR receiver
KM390_23420	COG0666	response to abiotic stimulus
KM390_23455	COG1609	Transcriptional regulator
KM390_23460	COG4851	CamS sex pheromone cAM373 precursor
KM390_23465	COG3118	belongs to the thioredoxin family
KM390_23475	COG2309	aminopeptidase activity
KM390_23495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_23510	COG1674	ftsk spoiiie
KM390_23520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM390_23525	COG4848	Belongs to the UPF0354 family
KM390_23530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM390_23535	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM390_23540	COG1363	Peptidase, m42
KM390_23550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_23565	COG0510	thiamine kinase activity
KM390_23570	COG1523	belongs to the glycosyl hydrolase 13 family
KM390_23585	COG1349	DNA-binding transcription factor activity
KM390_23590	COG1187	pseudouridine synthase activity
KM390_23595	COG2244	polysaccharide biosynthetic process
KM390_23600	COG2081	HI0933 family
KM390_23605	COG2814	Major facilitator Superfamily
KM390_23615	COG3832	glyoxalase III activity
KM390_23635	COG1329	Transcriptional regulator
KM390_23645	COG4975	Glucose uptake
KM390_23660	COG0314	molybdopterin synthase activity
KM390_23665	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM390_23670	COG0303	'Molybdopterin
KM390_23680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM390_23705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM390_23715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM390_23755	COG2814	Major facilitator Superfamily
KM390_23760	COG0475	glutathione-regulated potassium exporter activity
KM390_23765	COG0490	domain, Protein
KM390_23770	COG0582	viral genome integration into host DNA
KM390_23780	COG1136	(ABC) transporter
KM390_23800	COG1242	4 iron, 4 sulfur cluster binding
KM390_23805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM390_23810	COG1131	(ABC) transporter
KM390_23820	COG1794	racemase activity, acting on amino acids and derivatives
KM390_23840	COG2267	carboxylic ester hydrolase activity
KM390_23845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM390_23850	COG0671	phosphoesterase, PA-phosphatase related
KM390_23855	COG0438	transferase activity, transferring glycosyl groups
KM390_23865	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM390_23920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM390_23925	COG5002	protein histidine kinase activity
KM390_23930	COG4191	Histidine kinase
KM390_23935	COG2267	carboxylic ester hydrolase activity
KM390_23955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM390_23960	COG1116	anion transmembrane transporter activity
KM390_23965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM390_23990	COG0494	nUDIX hydrolase
KM390_24020	COG0288	reversible hydration of carbon dioxide
KM390_24025	COG1271	oxidase subunit
KM390_24030	COG1294	oxidase, subunit
KM390_24050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_24075	COG1842	Phage shock protein A
KM390_24105	COG5002	protein histidine kinase activity
KM390_24110	COG0745	RESPONSE REGULATOR receiver
KM390_24140	COG1597	lipid kinase activity
KM390_24175	COG0586	Pfam SNARE associated Golgi protein
KM390_24185	COG0577	efflux transmembrane transporter activity
KM390_24190	COG1136	(ABC) transporter
KM390_24195	COG2207	Transcriptional regulator
KM390_24195	COG3708	Transcriptional regulator
KM390_24200	COG0745	RESPONSE REGULATOR receiver
KM390_24205	COG2205	protein histidine kinase activity
KM390_24210	COG0577	efflux transmembrane transporter activity
KM390_24220	COG0577	efflux transmembrane transporter activity
KM390_24225	COG1136	(ABC) transporter
KM390_24245	COG2188	Transcriptional regulator
KM390_24265	COG3964	amidohydrolase
KM390_24295	COG4948	Mandelate Racemase Muconate Lactonizing
KM390_24305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM390_24310	COG0596	Alpha beta hydrolase
KM390_24315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM390_24320	COG1169	isochorismate synthase
KM390_24325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM390_24330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM390_24350	COG0058	SHG alpha-glucan phosphorylase activity
KM390_24355	COG0297	glycogen (starch) synthase activity
KM390_24360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM390_24480	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM390_24515	COG1285	pathogenesis
KM390_24520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM390_24530	COG0166	Belongs to the GPI family
KM390_24535	COG2155	Conserved Protein
KM390_24540	COG1098	S1 RNA binding domain
KM390_24545	COG0436	Aminotransferase
KM390_24550	COG1522	sequence-specific DNA binding
KM390_24555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM390_24560	COG2267	carboxylic ester hydrolase activity
KM390_24570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM390_24590	COG5018	Exonuclease
KM390_24595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM390_24615	COG2050	protein possibly involved in aromatic compounds catabolism
KM390_24625	COG1268	BioY protein
KM390_24635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM390_24640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM390_24655	COG3584	3D domain protein
KM390_24670	COG1252	NADH dehydrogenase
KM390_24685	COG3708	Transcriptional regulator
KM390_24700	COG1683	Conserved Protein
KM390_24720	COG0316	Belongs to the HesB IscA family
KM390_24735	COG1252	NADH dehydrogenase
KM390_24750	COG0390	transport system, permease component
KM390_24755	COG2824	Alkylphosphonate utilization operon protein PhnA
KM390_24795	COG4837	Protein of unknown function (DUF1462)
KM390_24800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM390_24810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM390_24815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM390_24825	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM390_24830	COG0647	UMP catabolic process
KM390_24840	COG2445	Protein of unknown function DUF86
KM390_24845	COG1494	fructose-1,6-bisphosphatase
KM390_24860	COG4470	Protein conserved in bacteria
KM390_24870	COG0789	Transcriptional regulator
KM390_24875	COG4377	Putative membrane peptidase family (DUF2324)
KM390_24900	COG0739	heme binding
KM390_24910	COG3377	Domain of unknown function (DUF1805)
KM390_24915	COG0737	Belongs to the 5'-nucleotidase family
KM390_24920	COG1695	Transcriptional regulator
KM390_24930	COG0719	Fe-S assembly protein
KM390_24935	COG0822	iron-sulfur transferase activity
KM390_24940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM390_24945	COG0719	Fe-S assembly protein
KM390_24950	COG0396	ATPase activity
KM390_24955	COG1464	Belongs to the NlpA lipoprotein family
KM390_24960	COG1464	Belongs to the NlpA lipoprotein family
KM390_24965	COG2011	ABC-type metal ion transport system permease component
KM390_24970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM390_24980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM390_24985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM390_24995	COG1393	Belongs to the ArsC family
KM390_25040	COG0039	L-malate dehydrogenase activity
KM390_25060	COG1309	transcriptional regulator
KM390_25065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM390_25070	COG1960	acyl-CoA dehydrogenase activity
KM390_25075	COG0183	Belongs to the thiolase family
KM390_25080	COG1024	Enoyl-CoA hydratase
KM390_25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM390_25090	COG1686	Belongs to the peptidase S11 family
KM390_25105	COG0011	TIGRFAM Protein of
KM390_25110	COG0840	transmembrane signaling receptor activity
KM390_25130	COG2814	Major facilitator Superfamily
KM390_25135	COG0531	amino acid
KM390_25145	COG0706	membrane insertase activity
KM390_25155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM390_25190	COG0586	Pfam SNARE associated Golgi protein
KM390_25200	COG1376	ErfK ybiS ycfS ynhG family protein
KM390_25205	COG0745	RESPONSE REGULATOR receiver
KM390_25210	COG5002	protein histidine kinase activity
KM390_25235	COG2151	metal-sulfur cluster biosynthetic enzyme
KM390_25240	COG3227	Zinc metalloprotease (Elastase)
KM390_25245	COG1741	Belongs to the pirin family
KM390_25260	COG0475	glutathione-regulated potassium exporter activity
KM390_25265	COG0490	domain, Protein
KM390_25270	COG1115	amino acid carrier protein
KM390_25275	COG0783	Belongs to the Dps family
KM390_25290	COG1611	Belongs to the LOG family
KM390_25310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_25320	COG1115	amino acid carrier protein
KM390_25325	COG1115	amino acid carrier protein
KM390_25330	COG2910	NAD(P)H-binding
KM390_25345	COG0656	L-ascorbic acid biosynthetic process
KM390_25350	COG2814	Major facilitator Superfamily
KM390_25355	COG1733	regulation of RNA biosynthetic process
KM390_25365	COG1252	NADH dehydrogenase
KM390_25370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM390_25375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM390_25385	COG0840	transmembrane signaling receptor activity
KM390_25385	COG3290	protein histidine kinase activity
KM390_25395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM390_25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM390_25415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM390_25470	COG0557	exoribonuclease II activity
KM390_25475	COG1647	Serine aminopeptidase, S33
KM390_25480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM390_25485	COG1346	cytolysis
KM390_25585	COG4695	Portal protein
KM390_25610	COG4974	Belongs to the 'phage' integrase family
KM390_25620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM390_25625	COG0149	triose-phosphate isomerase activity
KM390_25635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM390_25650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM390_25675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM390_25690	COG2323	membrane
KM390_25695	COG0740	serine-type endopeptidase activity
KM390_25700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM390_25710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM390_25720	COG1051	belongs to the nudix hydrolase family
KM390_25730	COG0492	ferredoxin-NADP+ reductase activity
KM390_25735	COG0457	Tetratricopeptide repeat
KM390_25740	COG0110	maltose O-acetyltransferase activity
KM390_25760	COG1950	PFAM Membrane protein of
KM390_25770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM390_25775	COG0556	nucleotide-excision repair
KM390_25795	COG0789	Transcriptional regulator
KM390_25820	COG2855	membrane
KM390_25825	COG0583	DNA-binding transcription factor activity
KM390_25835	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM390_25840	COG0488	(ABC) transporter
KM390_25850	COG1132	(ABC) transporter
KM390_25855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM390_25860	COG0793	Belongs to the peptidase S41A family
KM390_25860	COG3409	Peptidoglycan-binding domain 1 protein
KM390_25865	COG2177	Part of the ABC transporter FtsEX involved in
KM390_25870	COG2884	Cell division ATP-binding protein ftsE
KM390_25885	COG0653	protein targeting
KM390_25890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM390_25895	COG1278	Cold shock
KM390_25900	COG1040	competence protein
KM390_25905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM390_25910	COG0791	NLP P60 protein
KM390_25910	COG1388	LysM domain
KM390_25915	COG1733	regulation of RNA biosynthetic process
KM390_25920	COG1307	EDD domain protein, DegV family
KM390_25925	COG1739	Uncharacterized protein family UPF0029
KM390_25930	COG1316	TRANSCRIPTIONal
KM390_25935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM390_25940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM390_25945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM390_25955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM390_25955	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM390_25970	COG3394	polysaccharide catabolic process
KM390_25975	COG1486	melibiose metabolic process
KM390_25980	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM390_25985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM390_25995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM390_26000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM390_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM390_26015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM390_26020	COG1301	dicarboxylic acid transport
KM390_26030	COG0346	lactoylglutathione lyase activity
KM390_26035	COG1511	domain protein
KM390_26040	COG0583	DNA-binding transcription factor activity
KM390_26045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM390_26060	COG1271	oxidase subunit
KM390_26065	COG1294	oxidase, subunit
KM390_26070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM390_26090	COG2389	metal-binding protein
KM390_26100	COG1368	sulfuric ester hydrolase activity
KM390_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM390_26125	COG1215	transferase activity, transferring glycosyl groups
KM390_26130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM390_26135	COG3584	3D domain protein
KM390_26135	COG1388	LysM domain
KM390_26160	COG4715	Zinc finger, swim domain protein
KM390_26165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM390_26205	COG0577	efflux transmembrane transporter activity
KM390_26210	COG1136	(ABC) transporter
KM390_26245	COG5002	protein histidine kinase activity
KM390_26250	COG0745	RESPONSE REGULATOR receiver
KM390_26255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM390_26270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM390_26275	COG1134	teichoic acid transport
KM390_26280	COG1682	transport, permease protein
KM390_26285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM390_26330	COG1609	Transcriptional regulator
KM390_26345	COG0739	heme binding
KM390_26365	COG2385	sporulation resulting in formation of a cellular spore
KM390_26380	COG4836	Membrane
KM390_26385	COG1007	ATP synthesis coupled electron transport
KM390_26390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM390_26395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM390_26405	COG0839	Belongs to the complex I subunit 6 family
KM390_26420	COG0649	NAD binding
KM390_26425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM390_26440	COG5001	Diguanylate cyclase
KM390_26440	COG3300	MHYT domain
KM390_26490	COG0356	it plays a direct role in the translocation of protons across the membrane
KM390_26525	COG0698	ribose 5-phosphate isomerase
KM390_26535	COG2190	(PTS) system
KM390_26540	COG2259	Doxx family
KM390_26545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM390_26560	COG0009	L-threonylcarbamoyladenylate synthase
KM390_26575	COG2890	protein-(glutamine-N5) methyltransferase activity
KM390_26595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM390_26600	COG1494	fructose-1,6-bisphosphatase
KM390_26620	COG4821	SIS domain
KM390_26630	COG3343	RNA polymerase activity
KM390_26640	COG1960	acyl-CoA dehydrogenase activity
KM390_26645	COG1960	acyl-CoA dehydrogenase activity
KM390_26650	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM390_26655	COG0183	Belongs to the thiolase family
KM390_26660	COG2181	nitrate reductase activity
KM390_26660	COG0247	lactate metabolic process
KM390_26665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM390_26675	COG5001	Diguanylate cyclase
KM390_26675	COG3300	MHYT domain
KM390_26695	COG2197	response regulator
KM390_26700	COG4585	Histidine kinase
KM390_26705	COG0842	Transport permease protein
KM390_26710	COG1131	(ABC) transporter
KM390_26715	COG0024	Methionine aminopeptidase
KM390_26725	COG2234	aminopeptidase activity
KM390_26745	COG1595	DNA-templated transcription, initiation
KM390_26750	COG0018	arginyl-trna synthetase
KM390_26755	COG4506	Protein conserved in bacteria
KM390_26760	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM390_26775	COG0010	Belongs to the arginase family
KM390_26785	COG2814	Major facilitator Superfamily
KM390_26790	COG0789	Transcriptional regulator
KM390_26795	COG0584	glycerophosphoryl diester phosphodiesterase
KM390_26800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM390_26810	COG1994	Peptidase M50
KM390_26820	COG1078	dGTPase activity
KM390_26825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM390_26830	COG1120	ATPase activity
KM390_26835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM390_26860	COG0095	Lipoate-protein ligase
KM390_26865	COG0280	phosphate acetyltransferase
KM390_26880	COG3773	Cell wall hydrolase
KM390_26890	COG2363	Small membrane protein
KM390_26900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM390_26905	COG2233	PERMEase
KM390_26910	COG0561	phosphatase activity
KM390_26915	COG2814	Major facilitator Superfamily
KM390_26925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM390_26930	COG1131	(ABC) transporter
KM390_26935	COG2755	lipolytic protein G-D-S-L family
KM390_26940	COG1609	Transcriptional regulator
KM390_26950	COG0460	homoserine dehydrogenase
KM390_26960	COG2873	o-acetylhomoserine
KM390_26970	COG1011	Hydrolase
KM390_26975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM390_26985	COG2197	response regulator
KM390_26995	COG0351	phosphomethylpyrimidine kinase
KM390_27000	COG3706	GGDEF domain
KM390_27005	COG2879	small protein
KM390_27010	COG1966	Carbon starvation protein
KM390_27015	COG3279	Response regulator of the LytR AlgR family
KM390_27020	COG0477	Major facilitator Superfamily
KM390_27045	COG0840	transmembrane signaling receptor activity
KM390_27055	COG1607	acyl-coa hydrolase
KM390_27070	COG0488	(ABC) transporter
KM390_27090	COG0463	Glycosyl transferase, family 2
KM390_27095	COG1309	transcriptional regulator
KM390_27100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM390_27105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM390_27105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM390_27110	COG0628	permease
KM390_27125	COG3279	Response regulator of the LytR AlgR family
KM390_27130	COG3275	phosphorelay sensor kinase activity
KM390_27135	COG2814	Major facilitator Superfamily
KM390_27140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM390_27145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM390_27150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM390_27170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM390_27175	COG1272	protein, Hemolysin III
KM390_27195	COG0516	GMP reductase activity
KM390_27200	COG1164	Oligoendopeptidase f
KM390_27220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM390_27225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM390_27230	COG4853	Protein conserved in bacteria
KM390_27235	COG4863	YycH protein
KM390_27240	COG5002	protein histidine kinase activity
KM390_27245	COG0745	RESPONSE REGULATOR receiver
KM390_27275	COG0305	Participates in initiation and elongation during chromosome replication
KM390_27285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM390_27290	COG4241	membrane
KM390_27300	COG0629	single-stranded DNA binding
KM390_27310	COG0012	GTP binding
KM390_27315	COG4481	Protein conserved in bacteria
KM390_27320	COG0668	transmembrane transport
KM390_27330	COG1475	DNA binding
KM390_27335	COG1192	Involved in chromosome partitioning
KM390_27360	COG1847	R3H domain protein
KM390_27365	COG0706	membrane insertase activity
KM390_27375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM390_27425	COG3344	reverse transcriptase
KM390_27505	COG3344	reverse transcriptase
KM390_27695	COG4962	Type ii secretion system protein e
KM390_27830	COG2311	Membrane
KM390_27850	COG4196	transglutaminase domain protein
KM390_27855	COG0671	phosphoesterase, PA-phosphatase related
KM390_27870	COG1215	transferase activity, transferring glycosyl groups
KM390_27875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM390_27880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM390_28040	COG2002	toxin-antitoxin pair type II binding
KM390_28050	COG4974	Belongs to the 'phage' integrase family
KM390_28100	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM390_28110	COG4974	Belongs to the 'phage' integrase family
KM390_28135	COG0457	Tetratricopeptide repeat
KM390_28340	COG0791	NLP P60 protein
KM390_28340	COG0741	lytic transglycosylase activity
KM390_28405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM390_28465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM390_28475	COG4166	transmembrane transport
KM390_28515	COG1280	lysine exporter protein (LysE YggA)
KM390_28540	COG0681	Belongs to the peptidase S26 family
KM390_28615	COG1309	transcriptional regulator
KM390_28620	COG1683	Conserved Protein
KM390_28660	COG1192	Involved in chromosome partitioning