locus-tag	class	description
KM397_00010	COG0592	DNA-directed DNA polymerase activity
KM397_00015	COG2501	S4 domain
KM397_00025	COG0187	DNA topoisomerase II activity
KM397_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM397_00065	COG0516	GMP reductase activity
KM397_00065	COG0517	IMP dehydrogenase activity
KM397_00070	COG1686	Belongs to the peptidase S11 family
KM397_00100	COG1428	Deoxynucleoside kinase
KM397_00105	COG1428	Deoxynucleoside kinase
KM397_00110	COG1335	isochorismatase
KM397_00115	COG0590	tRNA wobble adenosine to inosine editing
KM397_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM397_00180	COG1982	Orn Lys Arg decarboxylase major
KM397_00190	COG0470	DNA polymerase III
KM397_00195	COG1774	PSP1 C-terminal conserved region
KM397_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM397_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM397_00220	COG2002	toxin-antitoxin pair type II binding
KM397_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM397_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM397_00230	COG0084	hydrolase, TatD family'
KM397_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM397_00250	COG4466	Protein conserved in bacteria
KM397_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM397_00270	COG0251	oxidation-reduction process
KM397_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM397_00305	COG2002	toxin-antitoxin pair type II binding
KM397_00310	COG2244	polysaccharide biosynthetic process
KM397_00315	COG3956	TIGRFAM MazG family protein
KM397_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM397_00340	COG1098	S1 RNA binding domain
KM397_00355	COG2208	phosphoserine phosphatase activity
KM397_00360	COG0037	tRNA processing
KM397_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM397_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM397_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM397_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM397_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM397_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM397_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM397_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM397_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM397_00420	COG1396	sequence-specific DNA binding
KM397_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM397_00455	COG3880	PFAM UvrB UvrC protein
KM397_00465	COG0542	response to heat
KM397_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM397_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM397_00500	COG1045	serine acetyltransferase
KM397_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM397_00520	COG3688	RNA-binding protein containing a PIN domain
KM397_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM397_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM397_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM397_00565	COG2813	Specifically methylates the guanine in position
KM397_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM397_00580	COG1358	cellular component organization or biogenesis
KM397_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM397_00710	COG0201	protein transport
KM397_00720	COG0024	Methionine aminopeptidase
KM397_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM397_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM397_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM397_00795	COG0489	protein tyrosine kinase activity
KM397_00805	COG2194	sulfuric ester hydrolase activity
KM397_00810	COG0726	polysaccharide deacetylase
KM397_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM397_00895	COG4856	YbbR-like protein
KM397_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM397_00915	COG0596	Alpha beta hydrolase
KM397_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM397_00940	COG1506	peptidase
KM397_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM397_00940	COG4946	Tricorn protease homolog
KM397_00975	COG2011	ABC-type metal ion transport system permease component
KM397_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM397_00985	COG1464	Belongs to the NlpA lipoprotein family
KM397_00990	COG0604	alcohol dehydrogenase
KM397_01000	COG0277	FAD linked oxidase domain protein
KM397_01005	COG2271	Major facilitator Superfamily
KM397_01015	COG2814	Major facilitator Superfamily
KM397_01030	COG0601	transmembrane transport
KM397_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM397_01040	COG0444	Belongs to the ABC transporter superfamily
KM397_01045	COG4608	Belongs to the ABC transporter superfamily
KM397_01050	COG4166	transmembrane transport
KM397_01060	COG2207	Transcriptional regulator
KM397_01075	COG4166	transmembrane transport
KM397_01080	COG4166	transmembrane transport
KM397_01085	COG0656	L-ascorbic acid biosynthetic process
KM397_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM397_01105	COG4149	molybdate abc transporter
KM397_01115	COG1910	domain protein
KM397_01125	COG0583	DNA-binding transcription factor activity
KM397_01130	COG0697	spore germination
KM397_01145	COG0204	Acyl-transferase
KM397_01155	COG1609	Transcriptional regulator
KM397_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_01175	COG0084	hydrolase, TatD family'
KM397_01180	COG5298	Protein conserved in bacteria
KM397_01205	COG0488	(ABC) transporter
KM397_01220	COG0747	negative chemotaxis
KM397_01225	COG0601	transmembrane transport
KM397_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM397_01235	COG0444	Belongs to the ABC transporter superfamily
KM397_01240	COG4608	Belongs to the ABC transporter superfamily
KM397_01260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM397_01265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM397_01275	COG2814	Major facilitator Superfamily
KM397_01285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM397_01295	COG4294	response to UV
KM397_01300	COG0705	Rhomboid family
KM397_01300	COG0457	Tetratricopeptide repeat
KM397_01310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM397_01315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM397_01320	COG0864	Transcriptional regulator
KM397_01325	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM397_01330	COG2183	response to ionizing radiation
KM397_01425	COG0802	atpase or kinase
KM397_01430	COG1214	PFAM Peptidase M22, glycoprotease
KM397_01435	COG0456	acetyltransferase
KM397_01445	COG0488	(ABC) transporter
KM397_01460	COG1266	CAAX protease self-immunity
KM397_01480	COG2252	PERMEase
KM397_01490	COG5002	protein histidine kinase activity
KM397_01520	COG2226	methyltransferase
KM397_01560	COG1968	undecaprenyl-diphosphatase activity
KM397_01575	COG2205	protein histidine kinase activity
KM397_01580	COG0745	RESPONSE REGULATOR receiver
KM397_01600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM397_01605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM397_01610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM397_01620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM397_01635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM397_01645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM397_01655	COG0151	Belongs to the GarS family
KM397_01680	COG0210	DNA helicase
KM397_01690	COG4851	CamS sex pheromone cAM373 precursor
KM397_01710	COG1335	isochorismatase
KM397_01715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM397_01720	COG2011	ABC-type metal ion transport system permease component
KM397_01725	COG1464	Belongs to the NlpA lipoprotein family
KM397_01745	COG1846	Transcriptional regulator
KM397_01770	COG1597	lipid kinase activity
KM397_01775	COG0546	phosphoglycolate phosphatase activity
KM397_01780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM397_01790	COG1012	belongs to the aldehyde dehydrogenase family
KM397_01795	COG2076	Multidrug Resistance protein
KM397_01800	COG2309	aminopeptidase activity
KM397_01815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_01820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM397_01825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM397_01835	COG4807	Protein conserved in bacteria
KM397_01860	COG1757	Na H antiporter
KM397_01865	COG1473	amidohydrolase
KM397_01880	COG0450	alkyl hydroperoxide reductase
KM397_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_01905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_01910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_01925	COG0166	Belongs to the GPI family
KM397_01960	COG5002	protein histidine kinase activity
KM397_01980	COG3541	Predicted nucleotidyltransferase
KM397_01985	COG2814	Major facilitator Superfamily
KM397_01990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM397_01990	COG0723	plastoquinol--plastocyanin reductase activity
KM397_02000	COG0765	amino acid transport
KM397_02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM397_02015	COG0840	transmembrane signaling receptor activity
KM397_02020	COG0840	transmembrane signaling receptor activity
KM397_02025	COG0366	Alpha amylase catalytic
KM397_02030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_02030	COG1263	PTS System
KM397_02030	COG2190	(PTS) system
KM397_02060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM397_02075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM397_02085	COG1116	anion transmembrane transporter activity
KM397_02090	COG0488	(ABC) transporter
KM397_02135	COG2270	Major facilitator Superfamily
KM397_02150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM397_02165	COG2310	stress, protein
KM397_02170	COG2310	stress, protein
KM397_02175	COG2310	stress, protein
KM397_02180	COG0861	Integral membrane protein TerC family
KM397_02190	COG3853	Toxic anion resistance protein (TelA)
KM397_02205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM397_02215	COG1295	ribonuclease BN
KM397_02220	COG2217	Heavy metal translocating P-type atpase
KM397_02225	COG0697	spore germination
KM397_02245	COG0586	Pfam SNARE associated Golgi protein
KM397_02260	COG3871	stress protein (general stress protein 26)
KM397_02265	COG0387	Pfam Sodium calcium exchanger
KM397_02275	COG0535	radical SAM domain protein
KM397_02300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM397_02305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM397_02310	COG0582	viral genome integration into host DNA
KM397_02320	COG1396	sequence-specific DNA binding
KM397_02335	COG1396	sequence-specific DNA binding
KM397_02370	COG1484	DNA-dependent DNA replication
KM397_02600	COG0101	tRNA pseudouridine synthase activity
KM397_02610	COG3829	transcription factor binding
KM397_02620	COG0833	amino acid
KM397_02625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM397_02655	COG1263	PTS System
KM397_02655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_02660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM397_02675	COG0463	Glycosyl transferase, family 2
KM397_02690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM397_02690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM397_02710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM397_02730	COG1228	amidohydrolase
KM397_02735	COG1090	epimerase
KM397_02765	COG1988	membrane-bound metal-dependent
KM397_02770	COG1194	a g-specific adenine glycosylase
KM397_02795	COG1132	(ABC) transporter
KM397_02800	COG4129	membrane
KM397_02805	COG0070	glutamate synthase
KM397_02805	COG0069	glutamate synthase activity
KM397_02805	COG0067	glutamate synthase
KM397_02815	COG4555	ABC transporter
KM397_02835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM397_02840	COG0735	belongs to the Fur family
KM397_02955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM397_02960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM397_02970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM397_02980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM397_02990	COG2766	serine protein kinase
KM397_03010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM397_03020	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM397_03025	COG2268	Band 7 protein
KM397_03035	COG3290	protein histidine kinase activity
KM397_03045	COG2851	Citrate transporter
KM397_03065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM397_03070	COG3842	ATPase activity
KM397_03075	COG1175	transmembrane transport
KM397_03080	COG0395	ABC-type sugar transport system, permease component
KM397_03090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM397_03095	COG0745	RESPONSE REGULATOR receiver
KM397_03100	COG5002	protein histidine kinase activity
KM397_03110	COG4990	cell redox homeostasis
KM397_03120	COG3290	protein histidine kinase activity
KM397_03125	COG4565	transcriptional regulatory protein
KM397_03130	COG3493	citrate carrier protein
KM397_03135	COG0281	malic enzyme
KM397_03150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_03160	COG5002	protein histidine kinase activity
KM397_03165	COG0745	RESPONSE REGULATOR receiver
KM397_03170	COG0454	-acetyltransferase
KM397_03170	COG0456	acetyltransferase
KM397_03175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM397_03180	COG3383	formate dehydrogenase (NAD+) activity
KM397_03185	COG2427	Protein of unknown function (DUF1641)
KM397_03200	COG0531	amino acid
KM397_03205	COG0640	Transcriptional regulator
KM397_03210	COG2217	Heavy metal translocating P-type atpase
KM397_03215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM397_03230	COG3227	Zinc metalloprotease (Elastase)
KM397_03250	COG2720	vancomycin resistance protein
KM397_03255	COG1316	TRANSCRIPTIONal
KM397_03260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_03265	COG0346	lactoylglutathione lyase activity
KM397_03270	COG1253	flavin adenine dinucleotide binding
KM397_03275	COG1027	Aspartate ammonia-lyase
KM397_03280	COG1620	l-lactate permease
KM397_03295	COG3104	oligopeptide transport
KM397_03300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_03320	COG2226	methyltransferase
KM397_03325	COG0156	8-amino-7-oxononanoate synthase activity
KM397_03330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM397_03340	COG4548	von Willebrand factor, type A
KM397_03345	COG0714	Associated with various cellular activities
KM397_03350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM397_03370	COG0531	amino acid
KM397_03375	COG2188	Transcriptional regulator
KM397_03380	COG1263	PTS System
KM397_03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_03385	COG0366	Alpha amylase catalytic
KM397_03400	COG0697	spore germination
KM397_03410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM397_03415	COG1115	amino acid carrier protein
KM397_03420	COG1126	abc transporter atp-binding protein
KM397_03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM397_03430	COG0765	amino acid transport
KM397_03435	COG0765	amino acid transport
KM397_03440	COG0833	amino acid
KM397_03465	COG2378	regulation of single-species biofilm formation
KM397_03470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM397_03475	COG5002	protein histidine kinase activity
KM397_03490	COG0659	secondary active sulfate transmembrane transporter activity
KM397_03505	COG0747	negative chemotaxis
KM397_03515	COG0601	transmembrane transport
KM397_03520	COG4608	Belongs to the ABC transporter superfamily
KM397_03530	COG2271	Major facilitator Superfamily
KM397_03535	COG1846	Transcriptional regulator
KM397_03545	COG1609	Transcriptional regulator
KM397_03550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM397_03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM397_03570	COG1879	ABC-type sugar transport system periplasmic component
KM397_03595	COG1063	alcohol dehydrogenase
KM397_03610	COG3568	Endonuclease Exonuclease Phosphatase
KM397_03635	COG1968	undecaprenyl-diphosphatase activity
KM397_03640	COG0840	transmembrane signaling receptor activity
KM397_03645	COG1388	LysM domain
KM397_03645	COG3584	3D domain protein
KM397_03650	COG1476	TRANSCRIPTIONal
KM397_03665	COG3104	oligopeptide transport
KM397_03670	COG1114	Component of the transport system for branched-chain amino acids
KM397_03685	COG1113	amino acid transport
KM397_03690	COG2252	PERMEase
KM397_03715	COG0475	glutathione-regulated potassium exporter activity
KM397_03715	COG0569	domain protein
KM397_03730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM397_03735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM397_03740	COG4990	cell redox homeostasis
KM397_03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM397_03760	COG0697	spore germination
KM397_03765	COG0531	amino acid
KM397_03775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM397_03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM397_03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM397_03785	COG1918	ferrous iron import across plasma membrane
KM397_03790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM397_03795	COG0573	inorganic phosphate transmembrane transporter activity
KM397_03800	COG0581	inorganic phosphate transmembrane transporter activity
KM397_03810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM397_03925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM397_03945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM397_03950	COG1116	anion transmembrane transporter activity
KM397_03955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM397_03960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM397_03965	COG0352	thiamine-phosphate diphosphorylase activity
KM397_03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM397_03975	COG2104	thiamine diphosphate biosynthetic process
KM397_03985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM397_03990	COG0351	phosphomethylpyrimidine kinase
KM397_04030	COG2205	protein histidine kinase activity
KM397_04035	COG2814	Major facilitator Superfamily
KM397_04040	COG1846	Transcriptional regulator
KM397_04055	COG2252	PERMEase
KM397_04060	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_04075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM397_04080	COG1621	beta-fructofuranosidase activity
KM397_04085	COG1263	PTS System
KM397_04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_04090	COG1609	Transcriptional regulator
KM397_04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM397_04105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM397_04140	COG0778	Nitroreductase
KM397_04145	COG2719	SpoVR family
KM397_04170	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM397_04175	COG1937	Protein conserved in bacteria
KM397_04180	COG0425	Belongs to the sulfur carrier protein TusA family
KM397_04180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_04185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_04190	COG0425	Belongs to the sulfur carrier protein TusA family
KM397_04195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_04205	COG2210	Belongs to the sulfur carrier protein TusA family
KM397_04210	COG0730	response to heat
KM397_04220	COG1316	TRANSCRIPTIONal
KM397_04225	COG0604	alcohol dehydrogenase
KM397_04230	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM397_04245	COG3711	transcriptional antiterminator
KM397_04245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM397_04250	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM397_04255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM397_04275	COG3584	3D domain protein
KM397_04275	COG1388	LysM domain
KM397_04280	COG0577	efflux transmembrane transporter activity
KM397_04285	COG1136	(ABC) transporter
KM397_04295	COG5522	Integral membrane protein (intg_mem_TP0381)
KM397_04310	COG1114	Component of the transport system for branched-chain amino acids
KM397_04315	COG3546	catalase activity
KM397_04350	COG0586	Pfam SNARE associated Golgi protein
KM397_04385	COG0531	amino acid
KM397_04390	COG0475	glutathione-regulated potassium exporter activity
KM397_04400	COG1737	Transcriptional regulator
KM397_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_04410	COG1263	PTS System
KM397_04420	COG2259	Doxx family
KM397_04435	COG0697	spore germination
KM397_04440	COG1522	sequence-specific DNA binding
KM397_04455	COG2076	Multidrug Resistance protein
KM397_04460	COG1309	transcriptional regulator
KM397_04465	COG2814	Major facilitator Superfamily
KM397_04470	COG1733	regulation of RNA biosynthetic process
KM397_04480	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM397_04485	COG4533	DNA binding
KM397_04490	COG2211	Major facilitator Superfamily
KM397_04500	COG0693	protein deglycase activity
KM397_04505	COG0693	protein deglycase activity
KM397_04505	COG0753	catalase activity
KM397_04515	COG0531	amino acid
KM397_04520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM397_04530	COG1012	belongs to the aldehyde dehydrogenase family
KM397_04535	COG1132	(ABC) transporter
KM397_04545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM397_04550	COG0765	amino acid transport
KM397_04555	COG1126	abc transporter atp-binding protein
KM397_04570	COG0189	ligase activity
KM397_04600	COG0028	Belongs to the TPP enzyme family
KM397_04605	COG3527	Alpha-acetolactate decarboxylase
KM397_04620	COG0561	phosphatase activity
KM397_04635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM397_04650	COG0659	secondary active sulfate transmembrane transporter activity
KM397_04670	COG0653	protein targeting
KM397_04675	COG2244	polysaccharide biosynthetic process
KM397_04685	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM397_04690	COG4196	transglutaminase domain protein
KM397_04705	COG1696	Membrane protein involved in D-alanine export
KM397_04720	COG1024	Enoyl-CoA hydratase
KM397_04740	COG1363	Peptidase, m42
KM397_04760	COG3938	Belongs to the proline racemase family
KM397_04800	COG0601	transmembrane transport
KM397_04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM397_04815	COG4608	Belongs to the ABC transporter superfamily
KM397_04820	COG0322	excinuclease ABC activity
KM397_04850	COG0477	Major facilitator Superfamily
KM397_04855	COG3290	protein histidine kinase activity
KM397_04860	COG4565	transcriptional regulatory protein
KM397_04865	COG3181	Tripartite tricarboxylate transporter family receptor
KM397_04895	COG0789	Transcriptional regulator
KM397_04895	COG4978	Transcriptional regulator
KM397_04910	COG0305	Participates in initiation and elongation during chromosome replication
KM397_04950	COG0477	Major facilitator Superfamily
KM397_04995	COG3320	Male sterility
KM397_04995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM397_05000	COG1309	transcriptional regulator
KM397_05020	COG1183	phosphatidylcholine synthase activity
KM397_05040	COG2376	Dihydroxyacetone kinase
KM397_05050	COG2376	Dihydroxyacetone kinase
KM397_05055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM397_05060	COG1959	2 iron, 2 sulfur cluster binding
KM397_05090	COG2770	Histidine kinase
KM397_05090	COG3437	response regulator, receiver
KM397_05140	COG3237	CsbD-like
KM397_05165	COG1191	sigma factor activity
KM397_05175	COG2208	phosphoserine phosphatase activity
KM397_05180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM397_05185	COG0784	Response regulator, receiver
KM397_05185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM397_05185	COG2198	Histidine kinase
KM397_05185	COG2205	protein histidine kinase activity
KM397_05240	COG0420	3'-5' exonuclease activity
KM397_05245	COG4717	serine-type aminopeptidase activity
KM397_05265	COG1309	transcriptional regulator
KM397_05270	COG2814	Major facilitator Superfamily
KM397_05275	COG0346	lactoylglutathione lyase activity
KM397_05280	COG0346	lactoylglutathione lyase activity
KM397_05285	COG0457	Tetratricopeptide repeat
KM397_05290	COG2267	carboxylic ester hydrolase activity
KM397_05310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM397_05315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM397_05325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM397_05365	COG0477	Major facilitator Superfamily
KM397_05370	COG0477	Major facilitator Superfamily
KM397_05380	COG3973	AAA domain
KM397_05385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM397_05405	COG4980	gas vesicle protein
KM397_05410	COG0537	adenosine 5'-monophosphoramidase activity
KM397_05415	COG1131	(ABC) transporter
KM397_05420	COG4473	ABC transporter
KM397_05435	COG1309	transcriptional regulator
KM397_05445	COG3402	PFAM membrane-flanked domain
KM397_05495	COG3402	PFAM membrane-flanked domain
KM397_05500	COG3428	Bacterial PH domain
KM397_05505	COG2329	Antibiotic biosynthesis monooxygenase
KM397_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM397_05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM397_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM397_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM397_05560	COG1309	transcriptional regulator
KM397_05565	COG1511	domain protein
KM397_05590	COG1609	Transcriptional regulator
KM397_05600	COG1234	tRNA 3'-trailer cleavage
KM397_05605	COG0095	Lipoate-protein ligase
KM397_05615	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_05645	COG3209	COG3209 Rhs family protein
KM397_05685	COG1078	dGTPase activity
KM397_05695	COG1595	DNA-templated transcription, initiation
KM397_05700	COG2207	Transcriptional regulator
KM397_05700	COG3708	Transcriptional regulator
KM397_05715	COG2205	protein histidine kinase activity
KM397_05720	COG0745	RESPONSE REGULATOR receiver
KM397_05745	COG0501	Belongs to the peptidase M48B family
KM397_05750	COG0840	transmembrane signaling receptor activity
KM397_05755	COG0697	spore germination
KM397_05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM397_05780	COG2224	Isocitrate lyase
KM397_05805	COG4903	ComK protein
KM397_05810	COG0398	Pfam SNARE associated Golgi protein
KM397_05820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM397_05825	COG1074	ATP-dependent DNA helicase activity
KM397_05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM397_05895	COG0367	asparagine synthase
KM397_05900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM397_05905	COG0753	catalase activity
KM397_05910	COG0004	ammonium transporteR
KM397_05930	COG2996	Protein conserved in bacteria
KM397_05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM397_05950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_05965	COG0561	phosphatase activity
KM397_05975	COG0542	response to heat
KM397_05985	COG2267	carboxylic ester hydrolase activity
KM397_06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM397_06010	COG5504	Zn-dependent protease
KM397_06020	COG0180	Tryptophanyl-tRNA synthetase
KM397_06030	COG4166	transmembrane transport
KM397_06035	COG0601	transmembrane transport
KM397_06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM397_06045	COG0444	Belongs to the ABC transporter superfamily
KM397_06050	COG4608	Belongs to the ABC transporter superfamily
KM397_06055	COG0534	Mate efflux family protein
KM397_06060	COG4166	transmembrane transport
KM397_06075	COG0861	Integral membrane protein TerC family
KM397_06080	COG4862	establishment of competence for transformation
KM397_06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM397_06095	COG1164	Oligoendopeptidase f
KM397_06105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM397_06110	COG2346	COG2346, Truncated hemoglobins
KM397_06115	COG4116	CYTH
KM397_06125	COG2357	RelA SpoT domain protein
KM397_06135	COG0564	pseudouridine synthase activity
KM397_06155	COG1216	Glycosyl transferase, family 2
KM397_06155	COG0463	Glycosyl transferase, family 2
KM397_06175	COG0463	Glycosyl transferase, family 2
KM397_06175	COG0457	Tetratricopeptide repeat
KM397_06195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM397_06210	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM397_06255	COG2153	protein acetylation
KM397_06265	COG2382	esterase
KM397_06280	COG5492	domain, Protein
KM397_06285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM397_06295	COG0512	Glutamine amidotransferase of anthranilate synthase
KM397_06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM397_06330	COG1620	l-lactate permease
KM397_06335	COG5634	Uncharacterized conserved protein (DUF2278)
KM397_06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM397_06400	COG1476	TRANSCRIPTIONal
KM397_06460	COG2226	methyltransferase
KM397_06470	COG1686	Belongs to the peptidase S11 family
KM397_06475	COG0681	Belongs to the peptidase S26 family
KM397_06510	COG1012	belongs to the aldehyde dehydrogenase family
KM397_06515	COG3842	ATPase activity
KM397_06520	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM397_06525	COG1177	transmembrane transport
KM397_06530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM397_06540	COG2409	Drug exporters of the RND superfamily
KM397_06550	COG0564	pseudouridine synthase activity
KM397_06560	COG2340	Cysteine-rich secretory protein family
KM397_06565	COG0247	lactate metabolic process
KM397_06570	COG0277	FAD linked oxidase domain protein
KM397_06575	COG3835	regulator
KM397_06585	COG0745	RESPONSE REGULATOR receiver
KM397_06590	COG5002	protein histidine kinase activity
KM397_06595	COG2186	Transcriptional regulator
KM397_06615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM397_06630	COG2116	formate transmembrane transporter activity
KM397_06635	COG0861	Integral membrane protein TerC family
KM397_06640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM397_06650	COG2030	dehydratase
KM397_06670	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_06675	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM397_06680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM397_06685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM397_06700	COG1840	ABC-type Fe3 transport system, periplasmic component
KM397_06730	COG1349	DNA-binding transcription factor activity
KM397_06750	COG2861	carbohydrate metabolic process
KM397_06760	COG3852	Histidine kinase
KM397_06765	COG1846	Transcriptional regulator
KM397_06775	COG2318	DinB family
KM397_06780	COG5002	protein histidine kinase activity
KM397_06790	COG0720	synthase
KM397_06805	COG4873	Protein conserved in bacteria
KM397_06835	COG1780	Probably involved in ribonucleotide reductase function
KM397_06855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM397_06860	COG1725	Transcriptional regulator
KM397_06865	COG1131	(ABC) transporter
KM397_06875	COG1131	(ABC) transporter
KM397_06880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM397_06895	COG1522	sequence-specific DNA binding
KM397_06905	COG1335	isochorismatase
KM397_06915	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM397_06920	COG2070	2-Nitropropane dioxygenase
KM397_06925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM397_06935	COG1696	Membrane protein involved in D-alanine export
KM397_06960	COG0716	FMN binding
KM397_06975	COG3173	Aminoglycoside phosphotransferase
KM397_06995	COG0534	Mate efflux family protein
KM397_07000	COG1968	undecaprenyl-diphosphatase activity
KM397_07015	COG1846	Transcriptional regulator
KM397_07025	COG1301	dicarboxylic acid transport
KM397_07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM397_07035	COG4709	membrane
KM397_07040	COG3874	Sporulation protein YtfJ
KM397_07065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM397_07070	COG0028	Belongs to the TPP enzyme family
KM397_07075	COG0440	acetolactate synthase activity
KM397_07080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM397_07090	COG0473	3-isopropylmalate dehydrogenase activity
KM397_07115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM397_07150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM397_07165	COG1183	phosphatidylcholine synthase activity
KM397_07170	COG1368	sulfuric ester hydrolase activity
KM397_07180	COG0019	diaminopimelate decarboxylase activity
KM397_07200	COG0529	Catalyzes the synthesis of activated sulfate
KM397_07205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM397_07225	COG1648	precorrin-2 dehydrogenase activity
KM397_07230	COG0733	neurotransmitter:sodium symporter activity
KM397_07250	COG1757	Na H antiporter
KM397_07265	COG4758	membrane
KM397_07270	COG4585	Histidine kinase
KM397_07275	COG2197	response regulator
KM397_07285	COG1114	Component of the transport system for branched-chain amino acids
KM397_07295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM397_07320	COG1017	nitric oxide dioxygenase activity
KM397_07320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM397_07335	COG0730	response to heat
KM397_07340	COG0306	phosphate transporter
KM397_07345	COG1392	Phosphate transport regulator
KM397_07350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM397_07365	COG3852	Histidine kinase
KM397_07370	COG1801	Protein of unknown function DUF72
KM397_07380	COG0582	viral genome integration into host DNA
KM397_07385	COG5002	protein histidine kinase activity
KM397_07405	COG0392	lysyltransferase activity
KM397_07405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM397_07420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM397_07425	COG1686	Belongs to the peptidase S11 family
KM397_07430	COG2715	membrane protein required for spore maturation
KM397_07435	COG0700	Nucleoside recognition
KM397_07440	COG1187	pseudouridine synthase activity
KM397_07450	COG1333	cytochrome c biogenesis protein
KM397_07455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM397_07460	COG0745	RESPONSE REGULATOR receiver
KM397_07465	COG5002	protein histidine kinase activity
KM397_07470	COG2096	Adenosyltransferase
KM397_07485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM397_07490	COG1141	Ferredoxin
KM397_07495	COG4955	Helix-turn-helix domain
KM397_07500	COG0514	ATP-dependent DNA helicase (RecQ)
KM397_07505	COG1266	CAAX protease self-immunity
KM397_07525	COG4862	establishment of competence for transformation
KM397_07530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM397_07550	COG0492	ferredoxin-NADP+ reductase activity
KM397_07625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM397_07640	COG0142	geranyltranstransferase activity
KM397_07650	COG0142	geranyltranstransferase activity
KM397_07670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM397_07675	COG0457	Tetratricopeptide repeat
KM397_07695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM397_07705	COG4347	Protein of unknown function (DUF1405)
KM397_07720	COG2738	Putative neutral zinc metallopeptidase
KM397_07730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_07735	COG1694	Mazg nucleotide pyrophosphohydrolase
KM397_07750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM397_07755	COG0438	transferase activity, transferring glycosyl groups
KM397_07790	COG1199	ATP-dependent helicase activity
KM397_07790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM397_07810	COG3935	DnaD domain protein
KM397_07815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM397_07825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM397_07825	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM397_07885	COG0116	Belongs to the methyltransferase superfamily
KM397_07895	COG1199	ATP-dependent helicase activity
KM397_07900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM397_07910	COG3173	Aminoglycoside phosphotransferase
KM397_07915	COG0024	Methionine aminopeptidase
KM397_07925	COG2233	PERMEase
KM397_07930	COG2311	Membrane
KM397_07935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM397_07945	COG0456	acetyltransferase
KM397_07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM397_08020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM397_08035	COG1215	transferase activity, transferring glycosyl groups
KM397_08055	COG0454	-acetyltransferase
KM397_08075	COG0328	RNA-DNA hybrid ribonuclease activity
KM397_08115	COG1280	lysine exporter protein (LysE YggA)
KM397_08130	COG3162	membrane
KM397_08135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM397_08140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM397_08150	COG0475	glutathione-regulated potassium exporter activity
KM397_08155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM397_08170	COG2323	membrane
KM397_08175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM397_08230	COG1923	regulation of RNA biosynthetic process
KM397_08240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM397_08245	COG1360	Flagellar Motor Protein
KM397_08250	COG2201	protein-glutamate methylesterase activity
KM397_08255	COG2198	Histidine kinase
KM397_08255	COG0643	Histidine kinase
KM397_08260	COG2198	Histidine kinase
KM397_08260	COG0643	Histidine kinase
KM397_08265	COG1776	CheC inhibitor of MCP methylation
KM397_08265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM397_08280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM397_08300	COG1256	bacterial-type flagellum assembly
KM397_08325	COG1815	bacterial-type flagellum-dependent cell motility
KM397_08330	COG1558	bacterial-type flagellum-dependent cell motility
KM397_08345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM397_08355	COG1157	protein secretion by the type III secretion system
KM397_08395	COG0784	Response regulator, receiver
KM397_08395	COG0835	chemotaxis
KM397_08405	COG0463	Glycosyl transferase, family 2
KM397_08440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM397_08445	COG0741	lytic transglycosylase activity
KM397_08460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM397_08460	COG1776	CheC inhibitor of MCP methylation
KM397_08470	COG1338	Plays a role in the flagellum-specific transport system
KM397_08475	COG1987	bacterial-type flagellum assembly
KM397_08485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM397_08490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM397_08500	COG4786	Flagellar basal body rod
KM397_08505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM397_08530	COG1309	transcriptional regulator
KM397_08550	COG2329	Antibiotic biosynthesis monooxygenase
KM397_08575	COG0583	DNA-binding transcription factor activity
KM397_08580	COG3842	ATPase activity
KM397_08585	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM397_08595	COG1234	tRNA 3'-trailer cleavage
KM397_08620	COG1686	Belongs to the peptidase S11 family
KM397_08630	COG0406	alpha-ribazole phosphatase activity
KM397_08660	COG0367	asparagine synthase
KM397_08690	COG1802	Transcriptional regulator
KM397_08695	COG0697	spore germination
KM397_08700	COG0523	cobalamin synthesis protein
KM397_08705	COG0701	Predicted permease
KM397_08715	COG1216	Glycosyl transferase, family 2
KM397_08715	COG0438	transferase activity, transferring glycosyl groups
KM397_08720	COG1757	Na H antiporter
KM397_08725	COG0114	fumarate hydratase activity
KM397_08750	COG3340	Belongs to the peptidase S51 family
KM397_08770	COG0785	Cytochrome C biogenesis protein
KM397_08800	COG2733	membrane
KM397_08835	COG1131	(ABC) transporter
KM397_08850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM397_08855	COG0528	UMP kinase activity
KM397_08865	COG1027	Aspartate ammonia-lyase
KM397_08870	COG0281	malic enzyme
KM397_08875	COG4191	Histidine kinase
KM397_08880	COG0784	Response regulator, receiver
KM397_08885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM397_08940	COG1051	belongs to the nudix hydrolase family
KM397_08945	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM397_08955	COG2814	Major facilitator Superfamily
KM397_08970	COG1966	Carbon starvation protein
KM397_08985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_08995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM397_09005	COG2223	nitrite transmembrane transporter activity
KM397_09010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM397_09025	COG2244	polysaccharide biosynthetic process
KM397_09030	COG0733	neurotransmitter:sodium symporter activity
KM397_09040	COG5566	PFAM Mor transcription activator
KM397_09045	COG2323	membrane
KM397_09060	COG2084	Dehydrogenase
KM397_09075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM397_09085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM397_09090	COG0028	Belongs to the TPP enzyme family
KM397_09095	COG0440	acetolactate synthase activity
KM397_09100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM397_09110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM397_09135	COG2814	Major facilitator Superfamily
KM397_09140	COG3384	dioxygenase
KM397_09150	COG3279	Response regulator of the LytR AlgR family
KM397_09155	COG0427	acetyl-CoA hydrolase
KM397_09175	COG1073	alpha beta
KM397_09205	COG0535	radical SAM domain protein
KM397_09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_09215	COG0745	RESPONSE REGULATOR receiver
KM397_09230	COG1914	H( )-stimulated, divalent metal cation uptake system
KM397_09245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM397_09275	COG2390	Transcriptional regulator
KM397_09285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_09290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM397_09305	COG4224	UPF0291 protein
KM397_09325	COG0006	proline dipeptidase activity
KM397_09330	COG2132	Multicopper oxidase
KM397_09345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM397_09360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM397_09375	COG2372	response to copper ion
KM397_09375	COG1276	copper resistance
KM397_09380	COG4549	nuclear export factor GLE1
KM397_09390	COG0697	spore germination
KM397_09395	COG0583	DNA-binding transcription factor activity
KM397_09400	COG1959	2 iron, 2 sulfur cluster binding
KM397_09405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM397_09410	COG0778	Nitroreductase
KM397_09420	COG0628	permease
KM397_09430	COG1231	oxidoreductase activity
KM397_09435	COG0523	cobalamin synthesis protein
KM397_09450	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_09455	COG2030	dehydratase
KM397_09460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_09470	COG0411	ABC transporter
KM397_09490	COG0583	DNA-binding transcription factor activity
KM397_09500	COG1942	4-Oxalocrotonate Tautomerase
KM397_09510	COG1846	Transcriptional regulator
KM397_09520	COG1271	oxidase subunit
KM397_09525	COG1294	oxidase, subunit
KM397_09530	COG4988	ABC transporter
KM397_09535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM397_09555	COG1686	Belongs to the peptidase S11 family
KM397_09570	COG1388	LysM domain
KM397_09570	COG0791	NLP P60 protein
KM397_09585	COG0745	RESPONSE REGULATOR receiver
KM397_09590	COG5002	protein histidine kinase activity
KM397_09600	COG0300	oxidoreductase activity
KM397_09635	COG0460	homoserine dehydrogenase
KM397_09660	COG1316	TRANSCRIPTIONal
KM397_09670	COG0745	RESPONSE REGULATOR receiver
KM397_09675	COG5002	protein histidine kinase activity
KM397_09690	COG1285	pathogenesis
KM397_09695	COG1247	-acetyltransferase
KM397_09715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM397_09725	COG1082	Xylose isomerase domain protein TIM barrel
KM397_09740	COG1279	arginine transmembrane transporter activity
KM397_09750	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM397_09790	COG2002	toxin-antitoxin pair type II binding
KM397_09795	COG1404	Belongs to the peptidase S8 family
KM397_09800	COG0640	Transcriptional regulator
KM397_09805	COG0667	Aldo Keto reductase
KM397_09810	COG2814	Major facilitator Superfamily
KM397_09835	COG0840	transmembrane signaling receptor activity
KM397_09850	COG3949	Membrane
KM397_09855	COG0783	Belongs to the Dps family
KM397_09870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM397_09880	COG1231	oxidoreductase activity
KM397_09890	COG4989	oxidoreductase activity
KM397_09895	COG0523	cobalamin synthesis protein
KM397_09900	COG0456	acetyltransferase
KM397_09955	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM397_09955	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM397_09965	COG0702	epimerase
KM397_09975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM397_09985	COG4166	transmembrane transport
KM397_10000	COG0406	alpha-ribazole phosphatase activity
KM397_10010	COG5337	Spore coat protein CotH
KM397_10015	COG1051	belongs to the nudix hydrolase family
KM397_10020	COG0586	Pfam SNARE associated Golgi protein
KM397_10025	COG2244	polysaccharide biosynthetic process
KM397_10035	COG0701	Predicted permease
KM397_10040	COG3689	TIGRFAM TIGR03943 family protein
KM397_10045	COG1607	acyl-coa hydrolase
KM397_10055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM397_10070	COG0702	epimerase
KM397_10075	COG2839	Protein conserved in bacteria
KM397_10080	COG1253	flavin adenine dinucleotide binding
KM397_10095	COG1114	Component of the transport system for branched-chain amino acids
KM397_10100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM397_10120	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM397_10130	COG1876	peptidase activity
KM397_10140	COG0154	amidase activity
KM397_10145	COG2211	Major facilitator Superfamily
KM397_10165	COG0561	phosphatase activity
KM397_10175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM397_10180	COG4106	trans-aconitate 2-methyltransferase activity
KM397_10195	COG1819	glycosyl
KM397_10200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_10205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_10230	COG0456	acetyltransferase
KM397_10280	COG3874	Sporulation protein YtfJ
KM397_10305	COG2226	methyltransferase
KM397_10330	COG0346	lactoylglutathione lyase activity
KM397_10340	COG0604	alcohol dehydrogenase
KM397_10345	COG1595	DNA-templated transcription, initiation
KM397_10370	COG0386	Belongs to the glutathione peroxidase family
KM397_10375	COG1305	Transglutaminase-like
KM397_10380	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM397_10385	COG0714	Associated with various cellular activities
KM397_10400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM397_10405	COG1140	nitrate reductase beta subunit
KM397_10410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM397_10415	COG2181	nitrate reductase activity
KM397_10435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM397_10440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM397_10445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM397_10450	COG0303	'Molybdopterin
KM397_10455	COG0314	molybdopterin synthase activity
KM397_10465	COG2223	nitrite transmembrane transporter activity
KM397_10480	COG1648	precorrin-2 dehydrogenase activity
KM397_10490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM397_10490	COG1587	Uroporphyrinogen-III synthase
KM397_10495	COG2146	nitrite reductase [NAD(P)H] activity
KM397_10500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM397_10505	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM397_10540	COG2359	stage V sporulation protein S
KM397_10555	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM397_10570	COG1418	mRNA catabolic process
KM397_10575	COG0488	(ABC) transporter
KM397_10590	COG0629	single-stranded DNA binding
KM397_10605	COG1413	lyase activity
KM397_10620	COG2521	methyltransferase
KM397_10620	COG2136	Putative SAM-dependent methyltransferase
KM397_10625	COG0018	arginyl-trna synthetase
KM397_10650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM397_10670	COG0017	Asparaginyl-tRNA synthetase
KM397_10690	COG1674	ftsk spoiiie
KM397_10760	COG1929	Belongs to the glycerate kinase type-1 family
KM397_10765	COG0471	metal ion transport
KM397_10770	COG0745	RESPONSE REGULATOR receiver
KM397_10775	COG3850	Histidine kinase
KM397_10775	COG5002	protein histidine kinase activity
KM397_10790	COG0733	neurotransmitter:sodium symporter activity
KM397_10815	COG2610	gluconate transmembrane transporter activity
KM397_10820	COG1454	alcohol dehydrogenase
KM397_10825	COG1794	racemase activity, acting on amino acids and derivatives
KM397_10835	COG0456	acetyltransferase
KM397_10850	COG1131	(ABC) transporter
KM397_10865	COG0546	phosphoglycolate phosphatase activity
KM397_10885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM397_10900	COG0768	penicillin binding
KM397_10905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM397_10910	COG0204	Acyl-transferase
KM397_10915	COG1272	protein, Hemolysin III
KM397_10925	COG0805	protein transport
KM397_10935	COG1307	EDD domain protein, DegV family
KM397_10940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM397_10945	COG1999	signal sequence binding
KM397_10950	COG0071	Belongs to the small heat shock protein (HSP20) family
KM397_10955	COG0367	asparagine synthase
KM397_10970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_10975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM397_11000	COG1051	belongs to the nudix hydrolase family
KM397_11010	COG0668	transmembrane transport
KM397_11015	COG4585	Histidine kinase
KM397_11015	COG2203	Gaf domain
KM397_11020	COG2197	response regulator
KM397_11030	COG1064	alcohol dehydrogenase
KM397_11055	COG1070	Carbohydrate kinase
KM397_11060	COG1070	Carbohydrate kinase
KM397_11090	COG1125	glycine betaine transport
KM397_11090	COG0517	IMP dehydrogenase activity
KM397_11095	COG1174	glycine betaine transport
KM397_11130	COG1253	flavin adenine dinucleotide binding
KM397_11135	COG1012	belongs to the aldehyde dehydrogenase family
KM397_11140	COG5506	Protein of unknown function (DUF1694)
KM397_11155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM397_11160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM397_11165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM397_11170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM397_11175	COG0456	acetyltransferase
KM397_11180	COG3829	transcription factor binding
KM397_11185	COG1509	lysine 2,3-aminomutase activity
KM397_11225	COG4326	sporulation control protein
KM397_11230	COG0671	phosphoesterase, PA-phosphatase related
KM397_11235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM397_11240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM397_11270	COG1715	Restriction endonuclease
KM397_11270	COG1787	Restriction endonuclease
KM397_11360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM397_11400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM397_11400	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM397_11405	COG2814	Major facilitator Superfamily
KM397_11410	COG4841	protein insertion into membrane
KM397_11415	COG0372	Belongs to the citrate synthase family
KM397_11420	COG2079	MmgE PrpD family protein
KM397_11425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM397_11430	COG1960	acyl-CoA dehydrogenase activity
KM397_11435	COG2084	Dehydrogenase
KM397_11445	COG1280	lysine exporter protein (LysE YggA)
KM397_11450	COG1024	Enoyl-CoA hydratase
KM397_11465	COG0420	3'-5' exonuclease activity
KM397_11470	COG0419	ATPase involved in DNA repair
KM397_11490	COG2223	nitrite transmembrane transporter activity
KM397_11495	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_11500	COG1169	isochorismate synthase
KM397_11505	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM397_11510	COG1535	isochorismatase
KM397_11510	COG3433	isochorismatase activity
KM397_11515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM397_11520	COG3251	PFAM MbtH domain protein
KM397_11525	COG2814	Major facilitator Superfamily
KM397_11540	COG0776	regulation of translation
KM397_11550	COG2318	DinB family
KM397_11560	COG1115	amino acid carrier protein
KM397_11575	COG2329	Antibiotic biosynthesis monooxygenase
KM397_11580	COG1187	pseudouridine synthase activity
KM397_11585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM397_11600	COG0596	Alpha beta hydrolase
KM397_11605	COG2814	Major facilitator Superfamily
KM397_11625	COG2226	methyltransferase
KM397_11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_11705	COG1247	-acetyltransferase
KM397_11735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM397_11745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_11755	COG1278	Cold shock
KM397_11770	COG0010	Belongs to the arginase family
KM397_11775	COG0561	phosphatase activity
KM397_11820	COG0583	DNA-binding transcription factor activity
KM397_11825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM397_11840	COG0583	DNA-binding transcription factor activity
KM397_11845	COG2258	MOSC domain
KM397_11860	COG1132	(ABC) transporter
KM397_11865	COG1132	(ABC) transporter
KM397_11885	COG1396	sequence-specific DNA binding
KM397_11915	COG1595	DNA-templated transcription, initiation
KM397_11940	COG1649	PFAM Uncharacterised BCR, COG1649
KM397_11965	COG2971	BadF BadG BcrA BcrD
KM397_11970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM397_11975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM397_11995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_12025	COG1309	transcriptional regulator
KM397_12040	COG0577	efflux transmembrane transporter activity
KM397_12040	COG1136	(ABC) transporter
KM397_12045	COG0500	methyltransferase
KM397_12045	COG3615	Tellurite resistance protein tehB
KM397_12055	COG2226	methyltransferase
KM397_12060	COG3961	Belongs to the TPP enzyme family
KM397_12065	COG1846	Transcriptional regulator
KM397_12105	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM397_12120	COG1595	DNA-templated transcription, initiation
KM397_12130	COG0768	penicillin binding
KM397_12140	COG2367	Beta-lactamase
KM397_12145	COG0671	phosphoesterase, PA-phosphatase related
KM397_12150	COG1609	Transcriptional regulator
KM397_12155	COG2814	Major facilitator Superfamily
KM397_12160	COG0673	inositol 2-dehydrogenase activity
KM397_12170	COG1012	belongs to the aldehyde dehydrogenase family
KM397_12185	COG0191	fructose-bisphosphate aldolase activity
KM397_12190	COG3718	enzyme involved in inositol metabolism
KM397_12215	COG0457	Tetratricopeptide repeat
KM397_12220	COG1476	TRANSCRIPTIONal
KM397_12235	COG1876	peptidase activity
KM397_12255	COG1309	transcriptional regulator
KM397_12260	COG0488	(ABC) transporter
KM397_12275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_12290	COG1252	NADH dehydrogenase
KM397_12295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_12310	COG1131	(ABC) transporter
KM397_12320	COG1309	transcriptional regulator
KM397_12335	COG1960	acyl-CoA dehydrogenase activity
KM397_12340	COG0439	Biotin carboxylase
KM397_12345	COG0511	ligase activity, forming carbon-carbon bonds
KM397_12350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM397_12355	COG1024	Enoyl-CoA hydratase
KM397_12360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM397_12365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM397_12375	COG1247	-acetyltransferase
KM397_12380	COG0572	uridine kinase
KM397_12390	COG2318	DinB family
KM397_12395	COG1686	Belongs to the peptidase S11 family
KM397_12420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM397_12460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM397_12460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM397_12485	COG2814	Major facilitator Superfamily
KM397_12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM397_12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_12540	COG1063	alcohol dehydrogenase
KM397_12570	COG3773	Cell wall hydrolase
KM397_12580	COG0745	RESPONSE REGULATOR receiver
KM397_12610	COG1136	(ABC) transporter
KM397_12635	COG0460	homoserine dehydrogenase
KM397_12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_12650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM397_12715	COG2124	cytochrome p450
KM397_12750	COG0561	phosphatase activity
KM397_12760	COG5002	protein histidine kinase activity
KM397_12765	COG0768	penicillin binding
KM397_12770	COG1819	glycosyl
KM397_12775	COG1794	racemase activity, acting on amino acids and derivatives
KM397_12785	COG1122	ATPase activity
KM397_12810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM397_12815	COG0604	alcohol dehydrogenase
KM397_12820	COG0768	penicillin binding
KM397_12830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM397_12865	COG0693	protein deglycase activity
KM397_12895	COG2814	Major facilitator Superfamily
KM397_12910	COG0584	glycerophosphoryl diester phosphodiesterase
KM397_12930	COG0697	spore germination
KM397_12955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM397_12965	COG2223	nitrite transmembrane transporter activity
KM397_12980	COG2816	NAD+ diphosphatase activity
KM397_12985	COG0592	DNA-directed DNA polymerase activity
KM397_12990	COG1051	belongs to the nudix hydrolase family
KM397_13025	COG3878	Protein conserved in bacteria
KM397_13070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM397_13085	COG0322	excinuclease ABC activity
KM397_13125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM397_13150	COG1011	Hydrolase
KM397_13170	COG0076	glutamate decarboxylase activity
KM397_13190	COG3227	Zinc metalloprotease (Elastase)
KM397_13210	COG0201	protein transport
KM397_13220	COG0697	spore germination
KM397_13225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_13255	COG4129	membrane
KM397_13260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_13275	COG2959	enzyme of heme biosynthesis
KM397_13295	COG3483	tryptophan 2,3-dioxygenase activity
KM397_13300	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM397_13305	COG3844	kynureninase activity
KM397_13310	COG1309	transcriptional regulator
KM397_13340	COG3284	Transcriptional regulator
KM397_13360	COG1349	DNA-binding transcription factor activity
KM397_13380	COG1959	2 iron, 2 sulfur cluster binding
KM397_13395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM397_13400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM397_13405	COG0022	dehydrogenase e1 component
KM397_13410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM397_13420	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_13425	COG0456	acetyltransferase
KM397_13425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM397_13455	COG4176	ABC-type proline glycine betaine transport system permease component
KM397_13460	COG4175	Glycine betaine
KM397_13460	COG0517	IMP dehydrogenase activity
KM397_13485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM397_13490	COG2153	protein acetylation
KM397_13495	COG3397	chitin binding
KM397_13510	COG2205	protein histidine kinase activity
KM397_13535	COG2333	competence protein COMEC
KM397_13535	COG0658	competence protein
KM397_13585	COG3973	AAA domain
KM397_13600	COG2105	PFAM AIG2 family protein
KM397_13605	COG0514	ATP-dependent DNA helicase (RecQ)
KM397_13625	COG4637	Psort location Cytoplasmic, score
KM397_13650	COG3397	chitin binding
KM397_13665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM397_13670	COG1115	amino acid carrier protein
KM397_13675	COG1012	belongs to the aldehyde dehydrogenase family
KM397_13680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM397_13690	COG3938	Belongs to the proline racemase family
KM397_13695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM397_13735	COG0586	Pfam SNARE associated Golgi protein
KM397_13750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM397_13755	COG0519	Catalyzes the synthesis of GMP from XMP
KM397_13760	COG4166	transmembrane transport
KM397_13770	COG4948	Mandelate Racemase Muconate Lactonizing
KM397_13815	COG2936	dipeptidyl-peptidase activity
KM397_13820	COG5002	protein histidine kinase activity
KM397_13860	COG1164	Oligoendopeptidase f
KM397_13875	COG1307	EDD domain protein, DegV family
KM397_13895	COG2814	Major facilitator Superfamily
KM397_13905	COG1664	Polymer-forming cytoskeletal
KM397_13910	COG0789	Transcriptional regulator
KM397_13915	COG4533	DNA binding
KM397_13920	COG0477	Major facilitator Superfamily
KM397_13920	COG2814	Major facilitator Superfamily
KM397_13940	COG2261	transglycosylase associated protein
KM397_13955	COG2226	methyltransferase
KM397_13990	COG0436	Aminotransferase
KM397_13995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM397_14000	COG5146	pantothenate kinase activity
KM397_14065	COG0628	permease
KM397_14075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM397_14080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM397_14085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM397_14090	COG1116	anion transmembrane transporter activity
KM397_14110	COG2816	NAD+ diphosphatase activity
KM397_14130	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM397_14155	COG0697	spore germination
KM397_14160	COG2318	DinB family
KM397_14180	COG4912	Dna alkylation repair
KM397_14200	COG0861	Integral membrane protein TerC family
KM397_14205	COG1368	sulfuric ester hydrolase activity
KM397_14210	COG0488	(ABC) transporter
KM397_14220	COG1033	growth of symbiont in host cell
KM397_14220	COG2409	Drug exporters of the RND superfamily
KM397_14225	COG2409	Drug exporters of the RND superfamily
KM397_14225	COG1033	growth of symbiont in host cell
KM397_14230	COG1033	growth of symbiont in host cell
KM397_14230	COG2409	Drug exporters of the RND superfamily
KM397_14235	COG1309	transcriptional regulator
KM397_14250	COG0287	Prephenate dehydrogenase
KM397_14255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM397_14260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM397_14265	COG1605	Chorismate mutase
KM397_14265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM397_14300	COG3584	3D domain protein
KM397_14300	COG1388	LysM domain
KM397_14310	COG1595	DNA-templated transcription, initiation
KM397_14335	COG1879	ABC-type sugar transport system periplasmic component
KM397_14345	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM397_14355	COG2390	Transcriptional regulator
KM397_14390	COG2329	Antibiotic biosynthesis monooxygenase
KM397_14410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_14420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM397_14425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM397_14430	COG4187	Peptidase family M20/M25/M40
KM397_14435	COG1414	Transcriptional regulator
KM397_14440	COG0833	amino acid
KM397_14445	COG1690	Belongs to the RtcB family
KM397_14450	COG3239	Fatty acid desaturase
KM397_14455	COG1785	Belongs to the alkaline phosphatase family
KM397_14465	COG3655	Transcriptional regulator
KM397_14480	COG4377	Putative membrane peptidase family (DUF2324)
KM397_14490	COG3279	Response regulator of the LytR AlgR family
KM397_14500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_14505	COG0346	lactoylglutathione lyase activity
KM397_14525	COG0714	Associated with various cellular activities
KM397_14550	COG0463	Glycosyl transferase, family 2
KM397_14575	COG0463	Glycosyl transferase, family 2
KM397_14585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM397_14590	COG0753	catalase activity
KM397_14600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM397_14625	COG0714	Associated with various cellular activities
KM397_14635	COG0778	Nitroreductase
KM397_14640	COG1846	Transcriptional regulator
KM397_14675	COG1725	Transcriptional regulator
KM397_14685	COG1136	(ABC) transporter
KM397_14685	COG0577	efflux transmembrane transporter activity
KM397_14710	COG2207	Transcriptional regulator
KM397_14715	COG0456	acetyltransferase
KM397_14735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_14755	COG0642	Histidine kinase
KM397_14760	COG0745	RESPONSE REGULATOR receiver
KM397_14765	COG0596	Alpha beta hydrolase
KM397_14795	COG0730	response to heat
KM397_14805	COG0833	amino acid
KM397_14815	COG4335	DNA alkylation repair
KM397_14855	COG0768	penicillin binding
KM397_14865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM397_14895	COG1984	allophanate hydrolase subunit 2
KM397_14900	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM397_14905	COG1414	Transcriptional regulator
KM397_14920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM397_14925	COG0640	Transcriptional regulator
KM397_14935	COG1960	acyl-CoA dehydrogenase activity
KM397_14950	COG3314	Sporulation integral membrane protein YlbJ
KM397_14965	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM397_14980	COG3848	Pyruvate phosphate dikinase
KM397_14980	COG0574	Belongs to the PEP-utilizing enzyme family
KM397_14985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_15000	COG5577	PFAM Coat F domain
KM397_15005	COG3403	YqcI/YcgG family
KM397_15010	COG1280	lysine exporter protein (LysE YggA)
KM397_15045	COG1063	alcohol dehydrogenase
KM397_15060	COG1027	Aspartate ammonia-lyase
KM397_15065	COG0252	asparaginase activity
KM397_15070	COG1396	sequence-specific DNA binding
KM397_15080	COG0322	excinuclease ABC activity
KM397_15085	COG0531	amino acid
KM397_15090	COG1114	Component of the transport system for branched-chain amino acids
KM397_15095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM397_15105	COG0281	malic enzyme
KM397_15120	COG0531	amino acid
KM397_15130	COG0784	Response regulator, receiver
KM397_15140	COG2066	Belongs to the glutaminase family
KM397_15145	COG1115	amino acid carrier protein
KM397_15175	COG0737	Belongs to the 5'-nucleotidase family
KM397_15180	COG0753	catalase activity
KM397_15185	COG2267	carboxylic ester hydrolase activity
KM397_15190	COG1335	isochorismatase
KM397_15210	COG0583	DNA-binding transcription factor activity
KM397_15215	COG1846	Transcriptional regulator
KM397_15255	COG0415	Belongs to the DNA photolyase family
KM397_15260	COG0288	reversible hydration of carbon dioxide
KM397_15270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM397_15275	COG5609	conserved protein (DUF2294)
KM397_15290	COG1575	Belongs to the MenA family. Type 1 subfamily
KM397_15295	COG2267	carboxylic ester hydrolase activity
KM397_15300	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM397_15305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM397_15310	COG1121	(ABC) transporter
KM397_15340	COG0798	PFAM Bile acid sodium symporter
KM397_15345	COG0346	lactoylglutathione lyase activity
KM397_15350	COG0640	Transcriptional regulator
KM397_15365	COG0443	Heat shock 70 kDa protein
KM397_15380	COG1522	sequence-specific DNA binding
KM397_15395	COG0346	lactoylglutathione lyase activity
KM397_15420	COG2169	Transcriptional regulator
KM397_15465	COG2814	Major facilitator Superfamily
KM397_15490	COG0745	RESPONSE REGULATOR receiver
KM397_15495	COG3850	Histidine kinase
KM397_15495	COG5002	protein histidine kinase activity
KM397_15520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM397_15540	COG1476	TRANSCRIPTIONal
KM397_15555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_15560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM397_15570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_15575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM397_15590	COG1136	(ABC) transporter
KM397_15595	COG0577	efflux transmembrane transporter activity
KM397_15610	COG5002	protein histidine kinase activity
KM397_15610	COG3850	Histidine kinase
KM397_15620	COG2364	Membrane
KM397_15625	COG1846	Transcriptional regulator
KM397_15635	COG2808	Putative FMN-binding domain
KM397_15640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_15645	COG2271	Major facilitator Superfamily
KM397_15650	COG1556	Lactate utilization protein
KM397_15655	COG1139	Iron-sulfur cluster binding protein
KM397_15665	COG0583	DNA-binding transcription factor activity
KM397_15675	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM397_15695	COG0738	Major facilitator superfamily
KM397_15700	COG0673	inositol 2-dehydrogenase activity
KM397_15705	COG0561	phosphatase activity
KM397_15715	COG1609	Transcriptional regulator
KM397_15720	COG0457	Tetratricopeptide repeat
KM397_15740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM397_15770	COG0534	Mate efflux family protein
KM397_15790	COG2814	Major facilitator Superfamily
KM397_15795	COG1309	transcriptional regulator
KM397_15810	COG0814	amino acid
KM397_15815	COG1760	l-serine dehydratase
KM397_15820	COG1760	l-serine dehydratase
KM397_15830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM397_15835	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM397_15845	COG1335	isochorismatase
KM397_15850	COG1522	sequence-specific DNA binding
KM397_15855	COG0531	amino acid
KM397_15870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM397_15890	COG1595	DNA-templated transcription, initiation
KM397_15905	COG0662	Cupin 2, conserved barrel domain protein
KM397_15910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_15910	COG2207	Transcriptional regulator
KM397_15960	COG0477	Major facilitator Superfamily
KM397_15970	COG1846	Transcriptional regulator
KM397_15975	COG2814	Major facilitator Superfamily
KM397_15985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM397_15990	COG1131	(ABC) transporter
KM397_16010	COG2076	Multidrug Resistance protein
KM397_16015	COG1309	transcriptional regulator
KM397_16025	COG2031	fatty acid transporter
KM397_16035	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM397_16065	COG1122	ATPase activity
KM397_16070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM397_16085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM397_16090	COG1288	antiporter activity
KM397_16095	COG2356	endonuclease I
KM397_16110	COG3620	sequence-specific DNA binding
KM397_16115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM397_16120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM397_16125	COG0124	histidyl-tRNA synthetase
KM397_16140	COG1733	regulation of RNA biosynthetic process
KM397_16145	COG0778	Nitroreductase
KM397_16165	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_16175	COG1131	(ABC) transporter
KM397_16200	COG1011	Hydrolase
KM397_16210	COG2365	Tyrosine phosphatase family
KM397_16235	COG0346	lactoylglutathione lyase activity
KM397_16240	COG1940	carbohydrate kinase activity
KM397_16245	COG0738	Major facilitator superfamily
KM397_16250	COG0110	maltose O-acetyltransferase activity
KM397_16260	COG1136	(ABC) transporter
KM397_16260	COG0577	efflux transmembrane transporter activity
KM397_16275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM397_16280	COG0628	permease
KM397_16300	COG2226	methyltransferase
KM397_16310	COG0477	Major facilitator Superfamily
KM397_16340	COG1253	flavin adenine dinucleotide binding
KM397_16345	COG0789	Transcriptional regulator
KM397_16350	COG0697	spore germination
KM397_16355	COG1357	PFAM Pentapeptide repeats (8 copies)
KM397_16360	COG3813	Protein conserved in bacteria
KM397_16365	COG2706	6-phosphogluconolactonase activity
KM397_16370	COG1070	Carbohydrate kinase
KM397_16380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM397_16395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM397_16400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM397_16405	COG0604	alcohol dehydrogenase
KM397_16410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM397_16420	COG0604	alcohol dehydrogenase
KM397_16420	COG3321	synthase
KM397_16425	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_16450	COG0656	L-ascorbic acid biosynthetic process
KM397_16455	COG2814	Major facilitator Superfamily
KM397_16470	COG0346	lactoylglutathione lyase activity
KM397_16475	COG0814	amino acid
KM397_16500	COG1393	Belongs to the ArsC family
KM397_16505	COG1733	regulation of RNA biosynthetic process
KM397_16510	COG2188	Transcriptional regulator
KM397_16520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM397_16525	COG1733	regulation of RNA biosynthetic process
KM397_16530	COG1733	regulation of RNA biosynthetic process
KM397_16545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_16565	COG0384	phenazine biosynthesis protein PhzF
KM397_16575	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_16585	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_16595	COG1733	regulation of RNA biosynthetic process
KM397_16630	COG1191	sigma factor activity
KM397_16645	COG1309	transcriptional regulator
KM397_16665	COG3152	Membrane
KM397_16690	COG1151	hydroxylamine reductase activity
KM397_16700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_16705	COG3757	hydrolase, family 25
KM397_16705	COG3409	Peptidoglycan-binding domain 1 protein
KM397_16740	COG2072	flavoprotein involved in K transport
KM397_16775	COG0604	alcohol dehydrogenase
KM397_16780	COG1113	amino acid transport
KM397_16785	COG2814	Major facilitator Superfamily
KM397_16815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM397_16820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM397_16840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_16845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_16850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_16855	COG3739	integral membrane protein
KM397_16860	COG0384	phenazine biosynthesis protein PhzF
KM397_16890	COG0583	DNA-binding transcription factor activity
KM397_16910	COG1193	negative regulation of DNA recombination
KM397_16930	COG1164	Oligoendopeptidase f
KM397_16935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM397_16965	COG0584	glycerophosphoryl diester phosphodiesterase
KM397_16990	COG0640	Transcriptional regulator
KM397_16995	COG0604	alcohol dehydrogenase
KM397_17015	COG2808	Putative FMN-binding domain
KM397_17020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM397_17030	COG0385	Bile acid
KM397_17035	COG0277	FAD linked oxidase domain protein
KM397_17065	COG1216	Glycosyl transferase, family 2
KM397_17070	COG1024	Enoyl-CoA hydratase
KM397_17080	COG1285	pathogenesis
KM397_17095	COG2514	catechol 2,3-dioxygenase activity
KM397_17100	COG2720	vancomycin resistance protein
KM397_17140	COG0716	FMN binding
KM397_17170	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_17180	COG0165	Argininosuccinate lyase
KM397_17195	COG4145	pantothenate transmembrane transporter activity
KM397_17205	COG1012	belongs to the aldehyde dehydrogenase family
KM397_17210	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_17220	COG1657	PFAM Prenyltransferase squalene oxidase
KM397_17225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM397_17230	COG2962	Rard protein
KM397_17235	COG3326	Membrane
KM397_17250	COG0489	protein tyrosine kinase activity
KM397_17260	COG0314	molybdopterin synthase activity
KM397_17265	COG0303	'Molybdopterin
KM397_17270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM397_17275	COG2116	formate transmembrane transporter activity
KM397_17285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM397_17290	COG5609	conserved protein (DUF2294)
KM397_17295	COG2427	Protein of unknown function (DUF1641)
KM397_17300	COG3383	formate dehydrogenase (NAD+) activity
KM397_17305	COG0697	spore germination
KM397_17345	COG2226	methyltransferase
KM397_17350	COG4166	transmembrane transport
KM397_17355	COG4166	transmembrane transport
KM397_17360	COG4166	transmembrane transport
KM397_17365	COG1301	dicarboxylic acid transport
KM397_17370	COG1316	TRANSCRIPTIONal
KM397_17380	COG1595	DNA-templated transcription, initiation
KM397_17400	COG1131	(ABC) transporter
KM397_17410	COG0673	inositol 2-dehydrogenase activity
KM397_17415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM397_17420	COG0187	DNA topoisomerase II activity
KM397_17425	COG1832	CoA-binding protein
KM397_17430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM397_17435	COG0745	RESPONSE REGULATOR receiver
KM397_17450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM397_17455	COG4841	protein insertion into membrane
KM397_17460	COG0824	Thioesterase
KM397_17490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM397_17500	COG2274	protein secretion by the type I secretion system
KM397_17505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM397_17545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM397_17560	COG0183	Belongs to the thiolase family
KM397_17565	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_17570	COG1268	BioY protein
KM397_17575	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_17625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_17635	COG5002	protein histidine kinase activity
KM397_17640	COG0400	carboxylic ester hydrolase activity
KM397_17645	COG0346	lactoylglutathione lyase activity
KM397_17650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM397_17655	COG0069	glutamate synthase activity
KM397_17660	COG1902	pentaerythritol trinitrate reductase activity
KM397_17665	COG1329	Transcriptional regulator
KM397_17670	COG0010	Belongs to the arginase family
KM397_17695	COG2226	methyltransferase
KM397_17750	COG4846	Membrane protein involved in cytochrome C biogenesis
KM397_17755	COG0785	Cytochrome C biogenesis protein
KM397_17765	COG0583	DNA-binding transcription factor activity
KM397_17770	COG1380	Effector of murein hydrolase LrgA
KM397_17775	COG1346	cytolysis
KM397_17800	COG3409	Peptidoglycan-binding domain 1 protein
KM397_17800	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM397_17815	COG1132	(ABC) transporter
KM397_17820	COG1132	(ABC) transporter
KM397_17850	COG3639	organic phosphonate transmembrane transporter activity
KM397_17855	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM397_17875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM397_17895	COG1695	Transcriptional regulator
KM397_17930	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM397_17930	COG1388	LysM domain
KM397_17930	COG3409	Peptidoglycan-binding domain 1 protein
KM397_17935	COG4824	toxin secretion phage lysis holin
KM397_18090	COG1595	DNA-templated transcription, initiation
KM397_18135	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM397_18215	COG1396	sequence-specific DNA binding
KM397_18240	COG0174	glutamine synthetase
KM397_18245	COG0789	Transcriptional regulator
KM397_18250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM397_18260	COG2860	membrane
KM397_18270	COG0464	growth
KM397_18300	COG1388	LysM domain
KM397_18300	COG3584	3D domain protein
KM397_18305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM397_18305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM397_18305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM397_18310	COG1105	Belongs to the carbohydrate kinase PfkB family
KM397_18315	COG1349	DNA-binding transcription factor activity
KM397_18325	COG2322	membrane
KM397_18335	COG1113	amino acid transport
KM397_18350	COG1408	metallophosphoesterase
KM397_18355	COG2116	formate transmembrane transporter activity
KM397_18365	COG2217	Heavy metal translocating P-type atpase
KM397_18370	COG2608	mercury ion transmembrane transporter activity
KM397_18375	COG1937	Protein conserved in bacteria
KM397_18385	COG2819	hydrolase of the alpha beta superfamily
KM397_18390	COG1120	ATPase activity
KM397_18395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_18410	COG0708	Exodeoxyribonuclease III
KM397_18415	COG2169	Transcriptional regulator
KM397_18420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM397_18425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM397_18435	COG2364	Membrane
KM397_18450	COG2267	carboxylic ester hydrolase activity
KM397_18455	COG0346	lactoylglutathione lyase activity
KM397_18460	COG5001	Diguanylate cyclase
KM397_18460	COG3300	MHYT domain
KM397_18475	COG1346	cytolysis
KM397_18480	COG1380	Effector of murein hydrolase LrgA
KM397_18485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM397_18490	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM397_18490	COG0596	Alpha beta hydrolase
KM397_18495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM397_18515	COG1404	Belongs to the peptidase S8 family
KM397_18520	COG3773	Cell wall hydrolase
KM397_18525	COG0562	UDP-galactopyranose mutase
KM397_18530	COG1368	sulfuric ester hydrolase activity
KM397_18535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM397_18545	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM397_18570	COG1131	(ABC) transporter
KM397_18590	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM397_18595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM397_18600	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM397_18605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM397_18605	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM397_18615	COG2359	stage V sporulation protein S
KM397_18620	COG1692	metallophosphoesterase
KM397_18645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM397_18650	COG1426	Protein conserved in bacteria
KM397_18665	COG0300	oxidoreductase activity
KM397_18670	COG0612	Peptidase, M16
KM397_18675	COG0612	Peptidase, M16
KM397_18680	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM397_18690	COG3845	ABC transporter
KM397_18695	COG1744	ABC transporter substrate-binding protein PnrA-like
KM397_18700	COG2188	Transcriptional regulator
KM397_18705	COG1674	ftsk spoiiie
KM397_18715	COG0740	serine-type endopeptidase activity
KM397_18720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM397_18730	COG0527	aspartate kinase activity
KM397_18735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM397_18740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM397_18745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM397_18750	COG1873	PFAM PRC-barrel domain
KM397_18755	COG0612	Peptidase, M16
KM397_18760	COG0726	polysaccharide deacetylase
KM397_18775	COG0196	riboflavin kinase activity
KM397_18780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM397_18790	COG1550	Protein conserved in bacteria
KM397_18800	COG1358	cellular component organization or biogenesis
KM397_18805	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM397_18810	COG0195	Participates in both transcription termination and antitermination
KM397_18830	COG0750	zinc metalloprotease
KM397_18840	COG4589	Belongs to the CDS family
KM397_18845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM397_18855	COG0528	UMP kinase activity
KM397_18885	COG4974	Belongs to the 'phage' integrase family
KM397_18895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM397_18905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM397_18945	COG1837	Belongs to the UPF0109 family
KM397_18955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM397_18965	COG0552	protein localization to endoplasmic reticulum
KM397_18970	COG1196	nuclear chromosome segregation
KM397_18980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM397_18985	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_18990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM397_19005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM397_19010	COG1461	Dihydroxyacetone kinase
KM397_19015	COG1302	Protein conserved in bacteria
KM397_19030	COG1564	THIamine pyrophosphokinase
KM397_19035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM397_19040	COG1162	GTPase activity
KM397_19045	COG0515	serine threonine protein kinase
KM397_19045	COG2815	serine threonine protein kinase
KM397_19050	COG0631	protein serine/threonine phosphatase activity
KM397_19060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM397_19060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM397_19070	COG0242	peptide deformylase activity
KM397_19075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM397_19080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM397_19100	COG1561	YicC-like family, N-terminal region
KM397_19105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM397_19115	COG0006	proline dipeptidase activity
KM397_19130	COG3069	C4-dicarboxylate transmembrane transporter activity
KM397_19195	COG0564	pseudouridine synthase activity
KM397_19215	COG3599	regulation of cell shape
KM397_19220	COG2302	S4 RNA-binding domain
KM397_19225	COG0762	integral membrane protein
KM397_19235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM397_19240	COG1496	oxidoreductase activity
KM397_19245	COG1873	PFAM PRC-barrel domain
KM397_19250	COG1191	sigma factor activity
KM397_19255	COG1191	sigma factor activity
KM397_19265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM397_19270	COG0849	cell division
KM397_19275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM397_19280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM397_19290	COG0772	Belongs to the SEDS family
KM397_19305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM397_19310	COG0768	penicillin binding
KM397_19315	COG0768	penicillin binding
KM397_19320	COG4839	cell division protein FtsL
KM397_19335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM397_19350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM397_19355	COG1399	metal-binding, possibly nucleic acid-binding protein
KM397_19405	COG4824	toxin secretion phage lysis holin
KM397_19490	COG4626	Terminase
KM397_19490	COG1802	Transcriptional regulator
KM397_19515	COG0582	viral genome integration into host DNA
KM397_19580	COG0756	dUTP diphosphatase activity
KM397_19595	COG1191	sigma factor activity
KM397_19620	COG1484	DNA-dependent DNA replication
KM397_19650	COG1396	sequence-specific DNA binding
KM397_19665	COG1396	sequence-specific DNA binding
KM397_19680	COG0582	viral genome integration into host DNA
KM397_19690	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM397_19695	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM397_19700	COG3314	Sporulation integral membrane protein YlbJ
KM397_19710	COG0742	ribosomal rna small subunit methyltransferase
KM397_19725	COG3679	Belongs to the UPF0342 family
KM397_19730	COG0406	alpha-ribazole phosphatase activity
KM397_19745	COG2340	Cysteine-rich secretory protein family
KM397_19760	COG3336	cytochrome c oxidase
KM397_19795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM397_19800	COG0772	Belongs to the SEDS family
KM397_19810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM397_19815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM397_19825	COG4896	Protein conserved in bacteria
KM397_19840	COG1217	gtp-binding protein TYPA
KM397_19850	COG0483	inositol monophosphate 1-phosphatase activity
KM397_19870	COG1982	Orn Lys Arg decarboxylase major
KM397_19915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM397_19920	COG0022	dehydrogenase e1 component
KM397_19925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM397_19935	COG0242	peptide deformylase activity
KM397_19940	COG0561	phosphatase activity
KM397_19950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM397_19955	COG0569	domain protein
KM397_19975	COG0583	DNA-binding transcription factor activity
KM397_19980	COG0517	IMP dehydrogenase activity
KM397_19990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM397_20000	COG4703	Protein of unknown function (DUF1797)
KM397_20015	COG2200	EAL domain
KM397_20020	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_20025	COG1408	metallophosphoesterase
KM397_20035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM397_20070	COG2814	Major facilitator Superfamily
KM397_20090	COG3209	COG3209 Rhs family protein
KM397_20100	COG2205	protein histidine kinase activity
KM397_20110	COG0436	Aminotransferase
KM397_20115	COG1609	Transcriptional regulator
KM397_20120	COG3833	ABC-type maltose transport systems, permease component
KM397_20125	COG1175	transmembrane transport
KM397_20130	COG2182	Extracellular solute-binding protein
KM397_20140	COG0366	Alpha amylase catalytic
KM397_20145	COG3842	ATPase activity
KM397_20185	COG0183	Belongs to the thiolase family
KM397_20220	COG1695	Transcriptional regulator
KM397_20225	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_20235	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM397_20245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM397_20250	COG0436	Aminotransferase
KM397_20270	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM397_20290	COG2199	diguanylate cyclase activity
KM397_20295	COG0778	Nitroreductase
KM397_20320	COG2190	(PTS) system
KM397_20320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM397_20320	COG1263	PTS System
KM397_20325	COG3711	transcriptional antiterminator
KM397_20335	COG2188	Transcriptional regulator
KM397_20345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM397_20370	COG1547	Domain of unknown function (DUF309)
KM397_20375	COG0456	acetyltransferase
KM397_20380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM397_20385	COG4086	secreted protein
KM397_20395	COG0697	spore germination
KM397_20410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_20435	COG0733	neurotransmitter:sodium symporter activity
KM397_20455	COG1686	Belongs to the peptidase S11 family
KM397_20460	COG1725	Transcriptional regulator
KM397_20465	COG1131	(ABC) transporter
KM397_20480	COG1846	Transcriptional regulator
KM397_20495	COG0598	Magnesium transport protein CorA
KM397_20520	COG4974	Belongs to the 'phage' integrase family
KM397_20530	COG0735	belongs to the Fur family
KM397_20535	COG1300	Membrane
KM397_20555	COG0667	Aldo Keto reductase
KM397_20560	COG0656	L-ascorbic acid biosynthetic process
KM397_20565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM397_20565	COG0456	acetyltransferase
KM397_20575	COG0737	Belongs to the 5'-nucleotidase family
KM397_20575	COG1525	nuclease
KM397_20575	COG4085	toxin activity
KM397_20585	COG0596	Alpha beta hydrolase
KM397_20590	COG2056	Na+-H+ antiporter family
KM397_20595	COG1609	Transcriptional regulator
KM397_20600	COG0456	acetyltransferase
KM397_20605	COG1073	alpha beta
KM397_20620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM397_20620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM397_20625	COG0307	riboflavin synthase, alpha
KM397_20650	COG4106	trans-aconitate 2-methyltransferase activity
KM397_20655	COG1073	alpha beta
KM397_20655	COG2226	methyltransferase
KM397_20670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM397_20680	COG1757	Na H antiporter
KM397_20685	COG0737	Belongs to the 5'-nucleotidase family
KM397_20695	COG1522	sequence-specific DNA binding
KM397_20715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM397_20725	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM397_20740	COG0300	oxidoreductase activity
KM397_20750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM397_20755	COG1760	l-serine dehydratase
KM397_20760	COG1760	l-serine dehydratase
KM397_20780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM397_20790	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM397_20795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_20810	COG1376	ErfK ybiS ycfS ynhG family protein
KM397_20815	COG4129	membrane
KM397_20820	COG1126	abc transporter atp-binding protein
KM397_20825	COG0765	amino acid transport
KM397_20830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM397_20850	COG0772	Belongs to the SEDS family
KM397_20855	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM397_20860	COG0022	dehydrogenase e1 component
KM397_20865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM397_20870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM397_20885	COG0280	phosphate acetyltransferase
KM397_20890	COG3829	transcription factor binding
KM397_20890	COG3290	protein histidine kinase activity
KM397_20900	COG0584	glycerophosphoryl diester phosphodiesterase
KM397_20905	COG3093	addiction module antidote protein HigA
KM397_20915	COG0745	RESPONSE REGULATOR receiver
KM397_20920	COG0750	zinc metalloprotease
KM397_20925	COG0497	DNA recombination
KM397_20935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM397_20945	COG0142	geranyltranstransferase activity
KM397_20970	COG1302	Protein conserved in bacteria
KM397_20975	COG0439	Biotin carboxylase
KM397_20980	COG0511	ligase activity, forming carbon-carbon bonds
KM397_21025	COG3854	ATPases associated with a variety of cellular activities
KM397_21050	COG0006	proline dipeptidase activity
KM397_21065	COG3872	metal-dependent enzyme
KM397_21075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM397_21095	COG0095	Lipoate-protein ligase
KM397_21100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_21105	COG1609	Transcriptional regulator
KM397_21115	COG2076	Multidrug Resistance protein
KM397_21120	COG2076	Multidrug Resistance protein
KM397_21155	COG1131	(ABC) transporter
KM397_21160	COG1725	Transcriptional regulator
KM397_21190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM397_21245	COG4970	Tfp pilus assembly protein FimT
KM397_21255	COG1459	type II secretion system
KM397_21260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM397_21310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM397_21315	COG0646	methionine synthase
KM397_21315	COG1410	methionine synthase
KM397_21320	COG0646	methionine synthase
KM397_21320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM397_21325	COG0626	cystathionine gamma-synthase activity
KM397_21330	COG0626	cystathionine gamma-synthase activity
KM397_21350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_21360	COG1940	carbohydrate kinase activity
KM397_21365	COG4483	Protein conserved in bacteria
KM397_21370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM397_21375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM397_21380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM397_21385	COG0704	Plays a role in the regulation of phosphate uptake
KM397_21395	COG0581	inorganic phosphate transmembrane transporter activity
KM397_21400	COG0573	inorganic phosphate transmembrane transporter activity
KM397_21405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM397_21410	COG0768	penicillin binding
KM397_21415	COG0477	Major facilitator Superfamily
KM397_21420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM397_21445	COG0735	belongs to the Fur family
KM397_21450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM397_21455	COG1121	(ABC) transporter
KM397_21460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_21490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM397_21495	COG2384	SAM-dependent methyltransferase
KM397_21500	COG2010	Cytochrome c
KM397_21505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM397_21510	COG0358	DNA primase activity
KM397_21520	COG0517	IMP dehydrogenase activity
KM397_21535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM397_21540	COG0295	cytidine deaminase activity
KM397_21545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM397_21555	COG1480	7TM receptor with intracellular HD hydrolase
KM397_21560	COG1702	phosphate starvation-inducible protein PhoH
KM397_21575	COG1610	YqeY-like protein
KM397_21580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM397_21585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM397_21590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM397_21620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM397_21625	COG1733	regulation of RNA biosynthetic process
KM397_21650	COG1466	dna polymerase III delta subunit
KM397_21665	COG2131	deaminase
KM397_21670	COG1555	photosystem II stabilization
KM397_21670	COG1596	polysaccharide export
KM397_21675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM397_21680	COG2226	methyltransferase
KM397_21685	COG0799	negative regulation of ribosome biogenesis
KM397_21690	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM397_21700	COG1534	Rna-binding protein
KM397_21710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM397_21715	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM397_21740	COG1595	DNA-templated transcription, initiation
KM397_21750	COG0778	Nitroreductase
KM397_21755	COG2357	RelA SpoT domain protein
KM397_21765	COG1785	Belongs to the alkaline phosphatase family
KM397_21775	COG2267	carboxylic ester hydrolase activity
KM397_21810	COG1404	Belongs to the peptidase S8 family
KM397_21815	COG3186	Phenylalanine-4-hydroxylase
KM397_21830	COG2259	Doxx family
KM397_21870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_21880	COG1012	belongs to the aldehyde dehydrogenase family
KM397_21880	COG1454	alcohol dehydrogenase
KM397_21885	COG0626	cystathionine gamma-synthase activity
KM397_21890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM397_21915	COG0768	penicillin binding
KM397_21930	COG0826	peptidase U32
KM397_21935	COG0826	peptidase U32
KM397_21940	COG4122	O-methyltransferase activity
KM397_21945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM397_21965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM397_21975	COG0628	permease
KM397_21995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM397_22005	COG0482	sulfurtransferase activity
KM397_22010	COG1104	cysteine desulfurase activity
KM397_22015	COG1959	2 iron, 2 sulfur cluster binding
KM397_22020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM397_22030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM397_22055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM397_22065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM397_22065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM397_22070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM397_22075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM397_22075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM397_22085	COG2244	polysaccharide biosynthetic process
KM397_22090	COG2323	membrane
KM397_22100	COG1862	Preprotein translocase
KM397_22130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM397_22140	COG0697	spore germination
KM397_22145	COG0697	spore germination
KM397_22150	COG0640	Transcriptional regulator
KM397_22175	COG0157	Belongs to the NadC ModD family
KM397_22180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM397_22185	COG1104	cysteine desulfurase activity
KM397_22190	COG1827	regulation of RNA biosynthetic process
KM397_22195	COG2258	MOSC domain
KM397_22200	COG0077	Prephenate dehydratase
KM397_22205	COG0577	efflux transmembrane transporter activity
KM397_22210	COG0577	efflux transmembrane transporter activity
KM397_22215	COG1136	(ABC) transporter
KM397_22225	COG0745	RESPONSE REGULATOR receiver
KM397_22230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM397_22235	COG3290	protein histidine kinase activity
KM397_22245	COG2868	ribosomal protein
KM397_22255	COG1530	ribonuclease E activity
KM397_22260	COG1994	Peptidase M50
KM397_22265	COG0739	heme binding
KM397_22270	COG2894	cell division
KM397_22290	COG1077	Cell shape determining protein MreB Mrl
KM397_22310	COG0285	dihydrofolate synthase activity
KM397_22315	COG0525	valine-tRNA ligase activity
KM397_22325	COG1388	LysM domain
KM397_22335	COG0113	porphobilinogen synthase activity
KM397_22340	COG1587	Uroporphyrinogen-III synthase
KM397_22350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM397_22360	COG1846	Transcriptional regulator
KM397_22365	COG1764	response to oxidative stress
KM397_22380	COG1067	ATP-dependent peptidase activity
KM397_22380	COG0470	DNA polymerase III
KM397_22425	COG0622	Phosphoesterase
KM397_22440	COG5401	PFAM Sporulation and spore germination
KM397_22460	COG1309	transcriptional regulator
KM397_22475	COG2197	response regulator
KM397_22480	COG2233	PERMEase
KM397_22490	COG0402	S-adenosylhomocysteine deaminase activity
KM397_22495	COG0402	S-adenosylhomocysteine deaminase activity
KM397_22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM397_22515	COG0444	Belongs to the ABC transporter superfamily
KM397_22520	COG4608	Belongs to the ABC transporter superfamily
KM397_22525	COG3275	phosphorelay sensor kinase activity
KM397_22530	COG3279	Response regulator of the LytR AlgR family
KM397_22545	COG1983	PspC domain protein
KM397_22550	COG1396	sequence-specific DNA binding
KM397_22555	COG0697	spore germination
KM397_22565	COG1959	2 iron, 2 sulfur cluster binding
KM397_22570	COG1668	transmembrane transport
KM397_22575	COG4152	abc transporter atp-binding protein
KM397_22580	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM397_22590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM397_22595	COG1876	peptidase activity
KM397_22600	COG0824	Thioesterase
KM397_22605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM397_22610	COG1053	succinate dehydrogenase
KM397_22615	COG2009	succinate dehydrogenase
KM397_22620	COG1719	4-vinyl reductase, 4VR
KM397_22630	COG3118	belongs to the thioredoxin family
KM397_22635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM397_22640	COG2086	electron transfer activity
KM397_22645	COG1024	Enoyl-CoA hydratase
KM397_22650	COG1309	transcriptional regulator
KM397_22655	COG0318	PFAM AMP-dependent synthetase and ligase
KM397_22675	COG2318	DinB family
KM397_22705	COG1131	(ABC) transporter
KM397_22710	COG2205	protein histidine kinase activity
KM397_22715	COG0745	RESPONSE REGULATOR receiver
KM397_22725	COG4895	conserved protein (DUF2196)
KM397_22730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM397_22745	COG4509	Sortase family
KM397_22750	COG1120	ATPase activity
KM397_22765	COG5386	Cell surface protein
KM397_22775	COG5386	Cell surface protein
KM397_22780	COG1114	Component of the transport system for branched-chain amino acids
KM397_22785	COG1187	pseudouridine synthase activity
KM397_22795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM397_22795	COG1796	DNA polymerase
KM397_22800	COG1286	toxin biosynthetic process
KM397_22845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM397_22855	COG1418	mRNA catabolic process
KM397_22880	COG2814	Major facilitator Superfamily
KM397_22885	COG1566	PFAM secretion protein HlyD family protein
KM397_22890	COG1309	transcriptional regulator
KM397_22895	COG1363	Peptidase, m42
KM397_22920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM397_22930	COG1484	DNA-dependent DNA replication
KM397_22935	COG3611	Membrane attachment protein
KM397_22945	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM397_22950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM397_22955	COG0237	dephospho-CoA kinase activity
KM397_22960	COG1971	Probably functions as a manganese efflux pump
KM397_22970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM397_22970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM397_22975	COG5002	protein histidine kinase activity
KM397_22980	COG0745	RESPONSE REGULATOR receiver
KM397_23000	COG0538	isocitrate dehydrogenase activity
KM397_23005	COG0372	Belongs to the citrate synthase family
KM397_23015	COG0628	permease
KM397_23020	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM397_23045	COG1725	Transcriptional regulator
KM397_23050	COG0281	malic enzyme
KM397_23055	COG0587	DNA-directed DNA polymerase activity
KM397_23070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM397_23090	COG4109	DRTGG domain
KM397_23105	COG0006	proline dipeptidase activity
KM397_23140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_23145	COG0662	Cupin 2, conserved barrel domain protein
KM397_23155	COG1476	TRANSCRIPTIONal
KM397_23170	COG1028	Short-chain dehydrogenase reductase Sdr
KM397_23175	COG0589	response to stress
KM397_23215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_23235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM397_23240	COG0827	DNA restriction-modification system
KM397_23245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM397_23250	COG3874	Sporulation protein YtfJ
KM397_23265	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM397_23290	COG1104	cysteine desulfurase activity
KM397_23300	COG0583	DNA-binding transcription factor activity
KM397_23305	COG0697	spore germination
KM397_23315	COG1956	GAF domain-containing protein
KM397_23320	COG0626	cystathionine gamma-synthase activity
KM397_23350	COG1595	DNA-templated transcription, initiation
KM397_23360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM397_23365	COG0454	-acetyltransferase
KM397_23370	COG0517	IMP dehydrogenase activity
KM397_23375	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM397_23385	COG0745	RESPONSE REGULATOR receiver
KM397_23395	COG0666	response to abiotic stimulus
KM397_23430	COG1609	Transcriptional regulator
KM397_23435	COG4851	CamS sex pheromone cAM373 precursor
KM397_23440	COG3118	belongs to the thioredoxin family
KM397_23450	COG2309	aminopeptidase activity
KM397_23470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_23485	COG1674	ftsk spoiiie
KM397_23495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM397_23500	COG4848	Belongs to the UPF0354 family
KM397_23505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM397_23510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM397_23515	COG1363	Peptidase, m42
KM397_23525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_23540	COG0510	thiamine kinase activity
KM397_23545	COG1523	belongs to the glycosyl hydrolase 13 family
KM397_23560	COG1349	DNA-binding transcription factor activity
KM397_23565	COG1187	pseudouridine synthase activity
KM397_23570	COG2244	polysaccharide biosynthetic process
KM397_23575	COG2081	HI0933 family
KM397_23580	COG2814	Major facilitator Superfamily
KM397_23590	COG3832	glyoxalase III activity
KM397_23610	COG1329	Transcriptional regulator
KM397_23620	COG4975	Glucose uptake
KM397_23635	COG0314	molybdopterin synthase activity
KM397_23640	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM397_23645	COG0303	'Molybdopterin
KM397_23655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM397_23680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM397_23690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM397_23730	COG2814	Major facilitator Superfamily
KM397_23735	COG0475	glutathione-regulated potassium exporter activity
KM397_23740	COG0490	domain, Protein
KM397_23745	COG0582	viral genome integration into host DNA
KM397_23755	COG1136	(ABC) transporter
KM397_23775	COG1242	4 iron, 4 sulfur cluster binding
KM397_23780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM397_23785	COG1131	(ABC) transporter
KM397_23795	COG1794	racemase activity, acting on amino acids and derivatives
KM397_23815	COG2267	carboxylic ester hydrolase activity
KM397_23820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM397_23825	COG0671	phosphoesterase, PA-phosphatase related
KM397_23830	COG0438	transferase activity, transferring glycosyl groups
KM397_23840	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM397_23895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM397_23900	COG5002	protein histidine kinase activity
KM397_23905	COG4191	Histidine kinase
KM397_23910	COG2267	carboxylic ester hydrolase activity
KM397_23930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM397_23935	COG1116	anion transmembrane transporter activity
KM397_23940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM397_23965	COG0494	nUDIX hydrolase
KM397_23995	COG0288	reversible hydration of carbon dioxide
KM397_24000	COG1271	oxidase subunit
KM397_24005	COG1294	oxidase, subunit
KM397_24025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_24050	COG1842	Phage shock protein A
KM397_24080	COG5002	protein histidine kinase activity
KM397_24085	COG0745	RESPONSE REGULATOR receiver
KM397_24115	COG1597	lipid kinase activity
KM397_24150	COG0586	Pfam SNARE associated Golgi protein
KM397_24160	COG0577	efflux transmembrane transporter activity
KM397_24165	COG1136	(ABC) transporter
KM397_24170	COG2207	Transcriptional regulator
KM397_24170	COG3708	Transcriptional regulator
KM397_24175	COG0745	RESPONSE REGULATOR receiver
KM397_24180	COG2205	protein histidine kinase activity
KM397_24190	COG0577	efflux transmembrane transporter activity
KM397_24195	COG1136	(ABC) transporter
KM397_24215	COG2188	Transcriptional regulator
KM397_24235	COG3964	amidohydrolase
KM397_24265	COG4948	Mandelate Racemase Muconate Lactonizing
KM397_24275	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM397_24280	COG0596	Alpha beta hydrolase
KM397_24285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM397_24290	COG1169	isochorismate synthase
KM397_24295	COG1575	Belongs to the MenA family. Type 1 subfamily
KM397_24300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM397_24320	COG0058	SHG alpha-glucan phosphorylase activity
KM397_24325	COG0297	glycogen (starch) synthase activity
KM397_24330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM397_24450	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM397_24485	COG1285	pathogenesis
KM397_24490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM397_24500	COG0166	Belongs to the GPI family
KM397_24505	COG2155	Conserved Protein
KM397_24510	COG1098	S1 RNA binding domain
KM397_24515	COG0436	Aminotransferase
KM397_24520	COG1522	sequence-specific DNA binding
KM397_24525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM397_24530	COG2267	carboxylic ester hydrolase activity
KM397_24540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM397_24560	COG5018	Exonuclease
KM397_24565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM397_24585	COG2050	protein possibly involved in aromatic compounds catabolism
KM397_24595	COG1268	BioY protein
KM397_24605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM397_24610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM397_24625	COG3584	3D domain protein
KM397_24640	COG1252	NADH dehydrogenase
KM397_24655	COG3708	Transcriptional regulator
KM397_24670	COG1683	Conserved Protein
KM397_24690	COG0316	Belongs to the HesB IscA family
KM397_24705	COG1252	NADH dehydrogenase
KM397_24720	COG0390	transport system, permease component
KM397_24725	COG2824	Alkylphosphonate utilization operon protein PhnA
KM397_24765	COG4837	Protein of unknown function (DUF1462)
KM397_24770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM397_24780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM397_24785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM397_24795	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM397_24800	COG0647	UMP catabolic process
KM397_24810	COG2445	Protein of unknown function DUF86
KM397_24815	COG1494	fructose-1,6-bisphosphatase
KM397_24830	COG4470	Protein conserved in bacteria
KM397_24840	COG0789	Transcriptional regulator
KM397_24845	COG4377	Putative membrane peptidase family (DUF2324)
KM397_24870	COG0739	heme binding
KM397_24880	COG3377	Domain of unknown function (DUF1805)
KM397_24885	COG0737	Belongs to the 5'-nucleotidase family
KM397_24890	COG1695	Transcriptional regulator
KM397_24900	COG0719	Fe-S assembly protein
KM397_24905	COG0822	iron-sulfur transferase activity
KM397_24910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM397_24915	COG0719	Fe-S assembly protein
KM397_24920	COG0396	ATPase activity
KM397_24925	COG1464	Belongs to the NlpA lipoprotein family
KM397_24930	COG1464	Belongs to the NlpA lipoprotein family
KM397_24935	COG2011	ABC-type metal ion transport system permease component
KM397_24940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM397_24950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM397_24955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM397_24965	COG1393	Belongs to the ArsC family
KM397_25010	COG0039	L-malate dehydrogenase activity
KM397_25030	COG1309	transcriptional regulator
KM397_25035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM397_25040	COG1960	acyl-CoA dehydrogenase activity
KM397_25045	COG0183	Belongs to the thiolase family
KM397_25050	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM397_25050	COG1024	Enoyl-CoA hydratase
KM397_25060	COG1686	Belongs to the peptidase S11 family
KM397_25075	COG0011	TIGRFAM Protein of
KM397_25080	COG0840	transmembrane signaling receptor activity
KM397_25100	COG2814	Major facilitator Superfamily
KM397_25105	COG0531	amino acid
KM397_25115	COG0706	membrane insertase activity
KM397_25125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM397_25160	COG0586	Pfam SNARE associated Golgi protein
KM397_25170	COG1376	ErfK ybiS ycfS ynhG family protein
KM397_25175	COG0745	RESPONSE REGULATOR receiver
KM397_25180	COG5002	protein histidine kinase activity
KM397_25205	COG2151	metal-sulfur cluster biosynthetic enzyme
KM397_25210	COG3227	Zinc metalloprotease (Elastase)
KM397_25215	COG1741	Belongs to the pirin family
KM397_25230	COG0475	glutathione-regulated potassium exporter activity
KM397_25235	COG0490	domain, Protein
KM397_25240	COG1115	amino acid carrier protein
KM397_25245	COG0783	Belongs to the Dps family
KM397_25260	COG1611	Belongs to the LOG family
KM397_25280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_25285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_25290	COG1115	amino acid carrier protein
KM397_25295	COG1115	amino acid carrier protein
KM397_25300	COG2910	NAD(P)H-binding
KM397_25315	COG0656	L-ascorbic acid biosynthetic process
KM397_25320	COG2814	Major facilitator Superfamily
KM397_25325	COG1733	regulation of RNA biosynthetic process
KM397_25335	COG1252	NADH dehydrogenase
KM397_25340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM397_25345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM397_25355	COG0840	transmembrane signaling receptor activity
KM397_25355	COG3290	protein histidine kinase activity
KM397_25365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM397_25370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM397_25385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM397_25440	COG0557	exoribonuclease II activity
KM397_25445	COG1647	Serine aminopeptidase, S33
KM397_25450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM397_25455	COG1346	cytolysis
KM397_25555	COG4695	Portal protein
KM397_25580	COG4974	Belongs to the 'phage' integrase family
KM397_25590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM397_25595	COG0149	triose-phosphate isomerase activity
KM397_25605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM397_25620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM397_25645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM397_25660	COG2323	membrane
KM397_25665	COG0740	serine-type endopeptidase activity
KM397_25670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM397_25680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM397_25690	COG1051	belongs to the nudix hydrolase family
KM397_25700	COG0492	ferredoxin-NADP+ reductase activity
KM397_25705	COG0457	Tetratricopeptide repeat
KM397_25710	COG0110	maltose O-acetyltransferase activity
KM397_25730	COG1950	PFAM Membrane protein of
KM397_25740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM397_25745	COG0556	nucleotide-excision repair
KM397_25765	COG0789	Transcriptional regulator
KM397_25790	COG2855	membrane
KM397_25795	COG0583	DNA-binding transcription factor activity
KM397_25805	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM397_25810	COG0488	(ABC) transporter
KM397_25820	COG1132	(ABC) transporter
KM397_25825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM397_25830	COG0793	Belongs to the peptidase S41A family
KM397_25830	COG3409	Peptidoglycan-binding domain 1 protein
KM397_25835	COG2177	Part of the ABC transporter FtsEX involved in
KM397_25840	COG2884	Cell division ATP-binding protein ftsE
KM397_25855	COG0653	protein targeting
KM397_25860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM397_25865	COG1278	Cold shock
KM397_25870	COG1040	competence protein
KM397_25875	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM397_25880	COG0791	NLP P60 protein
KM397_25880	COG1388	LysM domain
KM397_25885	COG1733	regulation of RNA biosynthetic process
KM397_25890	COG1307	EDD domain protein, DegV family
KM397_25895	COG1739	Uncharacterized protein family UPF0029
KM397_25900	COG1316	TRANSCRIPTIONal
KM397_25905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM397_25910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM397_25915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM397_25925	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM397_25925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM397_25940	COG3394	polysaccharide catabolic process
KM397_25945	COG1486	melibiose metabolic process
KM397_25950	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM397_25955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM397_25965	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM397_25970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM397_25975	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM397_25985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM397_25990	COG1301	dicarboxylic acid transport
KM397_26000	COG0346	lactoylglutathione lyase activity
KM397_26005	COG1511	domain protein
KM397_26010	COG0583	DNA-binding transcription factor activity
KM397_26015	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM397_26030	COG1271	oxidase subunit
KM397_26035	COG1294	oxidase, subunit
KM397_26040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM397_26050	COG1620	l-lactate permease
KM397_26060	COG2389	metal-binding protein
KM397_26070	COG1368	sulfuric ester hydrolase activity
KM397_26085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM397_26100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM397_26105	COG3584	3D domain protein
KM397_26105	COG1388	LysM domain
KM397_26130	COG4715	Zinc finger, swim domain protein
KM397_26135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM397_26175	COG0577	efflux transmembrane transporter activity
KM397_26180	COG1136	(ABC) transporter
KM397_26215	COG5002	protein histidine kinase activity
KM397_26220	COG0745	RESPONSE REGULATOR receiver
KM397_26225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM397_26240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM397_26245	COG1134	teichoic acid transport
KM397_26250	COG1682	transport, permease protein
KM397_26255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM397_26300	COG1609	Transcriptional regulator
KM397_26315	COG0739	heme binding
KM397_26335	COG2385	sporulation resulting in formation of a cellular spore
KM397_26350	COG4836	Membrane
KM397_26355	COG1007	ATP synthesis coupled electron transport
KM397_26360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM397_26365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM397_26375	COG0839	Belongs to the complex I subunit 6 family
KM397_26390	COG0649	NAD binding
KM397_26395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM397_26410	COG5001	Diguanylate cyclase
KM397_26410	COG3300	MHYT domain
KM397_26460	COG0356	it plays a direct role in the translocation of protons across the membrane
KM397_26495	COG0698	ribose 5-phosphate isomerase
KM397_26505	COG2190	(PTS) system
KM397_26510	COG2259	Doxx family
KM397_26515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM397_26530	COG0009	L-threonylcarbamoyladenylate synthase
KM397_26545	COG2890	protein-(glutamine-N5) methyltransferase activity
KM397_26565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM397_26570	COG1494	fructose-1,6-bisphosphatase
KM397_26590	COG4821	SIS domain
KM397_26600	COG3343	RNA polymerase activity
KM397_26610	COG1960	acyl-CoA dehydrogenase activity
KM397_26615	COG1960	acyl-CoA dehydrogenase activity
KM397_26620	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM397_26625	COG0183	Belongs to the thiolase family
KM397_26630	COG2181	nitrate reductase activity
KM397_26630	COG0247	lactate metabolic process
KM397_26635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM397_26645	COG3300	MHYT domain
KM397_26645	COG5001	Diguanylate cyclase
KM397_26665	COG2197	response regulator
KM397_26670	COG4585	Histidine kinase
KM397_26675	COG0842	Transport permease protein
KM397_26680	COG1131	(ABC) transporter
KM397_26685	COG0024	Methionine aminopeptidase
KM397_26695	COG2234	aminopeptidase activity
KM397_26715	COG1595	DNA-templated transcription, initiation
KM397_26720	COG0018	arginyl-trna synthetase
KM397_26725	COG4506	Protein conserved in bacteria
KM397_26730	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM397_26745	COG0010	Belongs to the arginase family
KM397_26755	COG2814	Major facilitator Superfamily
KM397_26760	COG0789	Transcriptional regulator
KM397_26765	COG0584	glycerophosphoryl diester phosphodiesterase
KM397_26770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM397_26780	COG1994	Peptidase M50
KM397_26790	COG1078	dGTPase activity
KM397_26795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM397_26800	COG1120	ATPase activity
KM397_26805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM397_26830	COG0095	Lipoate-protein ligase
KM397_26835	COG0280	phosphate acetyltransferase
KM397_26850	COG3773	Cell wall hydrolase
KM397_26860	COG2363	Small membrane protein
KM397_26870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM397_26875	COG2233	PERMEase
KM397_26880	COG0561	phosphatase activity
KM397_26885	COG2814	Major facilitator Superfamily
KM397_26895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM397_26900	COG1131	(ABC) transporter
KM397_26905	COG2755	lipolytic protein G-D-S-L family
KM397_26910	COG1609	Transcriptional regulator
KM397_26920	COG0460	homoserine dehydrogenase
KM397_26930	COG2873	o-acetylhomoserine
KM397_26940	COG1011	Hydrolase
KM397_26945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM397_26955	COG2197	response regulator
KM397_26965	COG0351	phosphomethylpyrimidine kinase
KM397_26970	COG3706	GGDEF domain
KM397_26975	COG2879	small protein
KM397_26980	COG1966	Carbon starvation protein
KM397_26985	COG3279	Response regulator of the LytR AlgR family
KM397_26990	COG0477	Major facilitator Superfamily
KM397_27015	COG0840	transmembrane signaling receptor activity
KM397_27025	COG1607	acyl-coa hydrolase
KM397_27040	COG0488	(ABC) transporter
KM397_27060	COG0463	Glycosyl transferase, family 2
KM397_27065	COG1309	transcriptional regulator
KM397_27070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM397_27075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM397_27075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM397_27080	COG0628	permease
KM397_27095	COG3279	Response regulator of the LytR AlgR family
KM397_27100	COG3275	phosphorelay sensor kinase activity
KM397_27105	COG2814	Major facilitator Superfamily
KM397_27110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM397_27115	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM397_27120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM397_27140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM397_27145	COG1272	protein, Hemolysin III
KM397_27165	COG0516	GMP reductase activity
KM397_27170	COG1164	Oligoendopeptidase f
KM397_27190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM397_27195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM397_27200	COG4853	Protein conserved in bacteria
KM397_27205	COG4863	YycH protein
KM397_27210	COG5002	protein histidine kinase activity
KM397_27215	COG0745	RESPONSE REGULATOR receiver
KM397_27245	COG0305	Participates in initiation and elongation during chromosome replication
KM397_27255	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM397_27260	COG4241	membrane
KM397_27270	COG0629	single-stranded DNA binding
KM397_27280	COG0012	GTP binding
KM397_27285	COG4481	Protein conserved in bacteria
KM397_27290	COG0668	transmembrane transport
KM397_27300	COG1475	DNA binding
KM397_27305	COG1192	Involved in chromosome partitioning
KM397_27330	COG1847	R3H domain protein
KM397_27335	COG0706	membrane insertase activity
KM397_27345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM397_27395	COG3344	reverse transcriptase
KM397_27475	COG3344	reverse transcriptase
KM397_27665	COG4962	Type ii secretion system protein e
KM397_27800	COG2311	Membrane
KM397_27820	COG4196	transglutaminase domain protein
KM397_27825	COG0671	phosphoesterase, PA-phosphatase related
KM397_27840	COG1215	transferase activity, transferring glycosyl groups
KM397_27845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM397_27850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM397_28010	COG2002	toxin-antitoxin pair type II binding
KM397_28020	COG4974	Belongs to the 'phage' integrase family
KM397_28075	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM397_28085	COG4974	Belongs to the 'phage' integrase family
KM397_28110	COG0457	Tetratricopeptide repeat
KM397_28315	COG0791	NLP P60 protein
KM397_28315	COG0741	lytic transglycosylase activity
KM397_28380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM397_28440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM397_28450	COG4166	transmembrane transport
KM397_28515	COG0681	Belongs to the peptidase S26 family
KM397_28590	COG1309	transcriptional regulator
KM397_28595	COG1683	Conserved Protein
KM397_28635	COG1192	Involved in chromosome partitioning