locus-tag	class	description
KD35_00020	COG1271	oxidase subunit
KD35_00025	COG1294	oxidase, subunit
KD35_00030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_00040	COG1620	l-lactate permease
KD35_00050	COG2389	metal-binding protein
KD35_00060	COG1368	sulfuric ester hydrolase activity
KD35_00075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_00085	COG1215	transferase activity, transferring glycosyl groups
KD35_00095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_00100	COG1388	LysM domain
KD35_00100	COG3584	3D domain protein
KD35_00125	COG4715	Zinc finger, swim domain protein
KD35_00130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_00160	COG1191	sigma factor activity
KD35_00170	COG0577	efflux transmembrane transporter activity
KD35_00175	COG1136	(ABC) transporter
KD35_00210	COG5002	protein histidine kinase activity
KD35_00215	COG0745	RESPONSE REGULATOR receiver
KD35_00220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KD35_00240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KD35_00245	COG1134	teichoic acid transport
KD35_00250	COG1682	transport, permease protein
KD35_00255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KD35_00300	COG1609	Transcriptional regulator
KD35_00315	COG0739	heme binding
KD35_00330	COG3279	Response regulator of the LytR AlgR family
KD35_00335	COG4555	ABC transporter
KD35_00340	COG2385	sporulation resulting in formation of a cellular spore
KD35_00345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KD35_00355	COG4836	Membrane
KD35_00360	COG1007	ATP synthesis coupled electron transport
KD35_00365	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KD35_00370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KD35_00380	COG0839	Belongs to the complex I subunit 6 family
KD35_00395	COG0649	NAD binding
KD35_00400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KD35_00410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KD35_00415	COG5001	Diguanylate cyclase
KD35_00415	COG3300	MHYT domain
KD35_00465	COG0356	it plays a direct role in the translocation of protons across the membrane
KD35_00500	COG0698	ribose 5-phosphate isomerase
KD35_00510	COG2190	(PTS) system
KD35_00515	COG2259	Doxx family
KD35_00520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KD35_00535	COG0009	L-threonylcarbamoyladenylate synthase
KD35_00550	COG2890	protein-(glutamine-N5) methyltransferase activity
KD35_00555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KD35_00570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KD35_00575	COG1494	fructose-1,6-bisphosphatase
KD35_00580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KD35_00595	COG4821	SIS domain
KD35_00605	COG3343	RNA polymerase activity
KD35_00615	COG1960	acyl-CoA dehydrogenase activity
KD35_00620	COG1960	acyl-CoA dehydrogenase activity
KD35_00625	COG1250	3-hydroxyacyl-CoA dehydrogenase
KD35_00630	COG0183	Belongs to the thiolase family
KD35_00635	COG2181	nitrate reductase activity
KD35_00635	COG0247	lactate metabolic process
KD35_00640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_00650	COG5001	Diguanylate cyclase
KD35_00650	COG3300	MHYT domain
KD35_00665	COG2197	response regulator
KD35_00670	COG4585	Histidine kinase
KD35_00675	COG0842	Transport permease protein
KD35_00680	COG1131	(ABC) transporter
KD35_00685	COG0024	Methionine aminopeptidase
KD35_00705	COG2234	aminopeptidase activity
KD35_00725	COG1595	DNA-templated transcription, initiation
KD35_00730	COG0018	arginyl-trna synthetase
KD35_00735	COG4506	Protein conserved in bacteria
KD35_00740	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_00760	COG0010	Belongs to the arginase family
KD35_00765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KD35_00770	COG2814	Major facilitator Superfamily
KD35_00775	COG0789	Transcriptional regulator
KD35_00780	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_00785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_00795	COG1994	Peptidase M50
KD35_00805	COG1078	dGTPase activity
KD35_00810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_00815	COG1120	ATPase activity
KD35_00820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_00825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_00830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_00850	COG0095	Lipoate-protein ligase
KD35_00855	COG0280	phosphate acetyltransferase
KD35_00870	COG3773	Cell wall hydrolase
KD35_00880	COG2363	Small membrane protein
KD35_00890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KD35_00895	COG2233	PERMEase
KD35_00900	COG0561	phosphatase activity
KD35_00905	COG2814	Major facilitator Superfamily
KD35_00915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_00920	COG1131	(ABC) transporter
KD35_00925	COG2755	lipolytic protein G-D-S-L family
KD35_00930	COG1609	Transcriptional regulator
KD35_00940	COG0460	homoserine dehydrogenase
KD35_00960	COG1011	Hydrolase
KD35_00965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KD35_00975	COG2197	response regulator
KD35_00985	COG0351	phosphomethylpyrimidine kinase
KD35_00990	COG3706	GGDEF domain
KD35_00995	COG2879	small protein
KD35_01000	COG1966	Carbon starvation protein
KD35_01005	COG3279	Response regulator of the LytR AlgR family
KD35_01010	COG0477	Major facilitator Superfamily
KD35_01035	COG0840	transmembrane signaling receptor activity
KD35_01045	COG1607	acyl-coa hydrolase
KD35_01060	COG0488	(ABC) transporter
KD35_01085	COG0463	Glycosyl transferase, family 2
KD35_01090	COG1309	transcriptional regulator
KD35_01095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KD35_01100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_01100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_01105	COG0628	permease
KD35_01120	COG3279	Response regulator of the LytR AlgR family
KD35_01125	COG3275	phosphorelay sensor kinase activity
KD35_01130	COG2814	Major facilitator Superfamily
KD35_01135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_01140	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KD35_01145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_01165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KD35_01170	COG1272	protein, Hemolysin III
KD35_01190	COG0516	GMP reductase activity
KD35_01195	COG1164	Oligoendopeptidase f
KD35_01215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_01220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KD35_01225	COG4853	Protein conserved in bacteria
KD35_01230	COG4863	YycH protein
KD35_01235	COG5002	protein histidine kinase activity
KD35_01240	COG0745	RESPONSE REGULATOR receiver
KD35_01270	COG0305	Participates in initiation and elongation during chromosome replication
KD35_01280	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KD35_01285	COG4241	membrane
KD35_01295	COG0629	single-stranded DNA binding
KD35_01305	COG0012	GTP binding
KD35_01310	COG4481	Protein conserved in bacteria
KD35_01315	COG0668	transmembrane transport
KD35_01325	COG1475	DNA binding
KD35_01330	COG1192	Involved in chromosome partitioning
KD35_01350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KD35_01355	COG1847	R3H domain protein
KD35_01360	COG0706	membrane insertase activity
KD35_01380	COG0592	DNA-directed DNA polymerase activity
KD35_01385	COG2501	S4 domain
KD35_01395	COG0187	DNA topoisomerase II activity
KD35_01400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KD35_01435	COG0516	GMP reductase activity
KD35_01435	COG0517	IMP dehydrogenase activity
KD35_01440	COG1686	Belongs to the peptidase S11 family
KD35_01470	COG1428	Deoxynucleoside kinase
KD35_01475	COG1428	Deoxynucleoside kinase
KD35_01480	COG1335	isochorismatase
KD35_01490	COG0590	tRNA wobble adenosine to inosine editing
KD35_01495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KD35_01550	COG1982	Orn Lys Arg decarboxylase major
KD35_01560	COG0470	DNA polymerase III
KD35_01565	COG1774	PSP1 C-terminal conserved region
KD35_01575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KD35_01585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KD35_01590	COG2002	toxin-antitoxin pair type II binding
KD35_01595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_01595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_01600	COG0084	hydrolase, TatD family'
KD35_01605	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KD35_01620	COG4466	Protein conserved in bacteria
KD35_01635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KD35_01640	COG0251	oxidation-reduction process
KD35_01655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KD35_01660	COG0193	aminoacyl-tRNA hydrolase activity
KD35_01670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KD35_01675	COG2002	toxin-antitoxin pair type II binding
KD35_01680	COG2244	polysaccharide biosynthetic process
KD35_01685	COG3956	TIGRFAM MazG family protein
KD35_01690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KD35_01710	COG1098	S1 RNA binding domain
KD35_01725	COG2208	phosphoserine phosphatase activity
KD35_01730	COG0037	tRNA processing
KD35_01740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KD35_01755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_01760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KD35_01765	COG0512	Glutamine amidotransferase of anthranilate synthase
KD35_01770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_01775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KD35_01780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KD35_01785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KD35_01790	COG1396	sequence-specific DNA binding
KD35_01795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KD35_01825	COG3880	PFAM UvrB UvrC protein
KD35_01835	COG0542	response to heat
KD35_01840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KD35_01850	COG4956	integral membrane protein (PIN domain superfamily)
KD35_01870	COG1045	serine acetyltransferase
KD35_01885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KD35_01890	COG3688	RNA-binding protein containing a PIN domain
KD35_01900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KD35_01905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KD35_01910	COG0250	Participates in transcription elongation, termination and antitermination
KD35_01935	COG2813	Specifically methylates the guanine in position
KD35_01945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KD35_01950	COG1358	cellular component organization or biogenesis
KD35_02055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KD35_02080	COG0201	protein transport
KD35_02090	COG0024	Methionine aminopeptidase
KD35_02100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KD35_02130	COG1122	ATPase activity
KD35_02135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KD35_02140	COG0101	tRNA pseudouridine synthase activity
KD35_02160	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_02165	COG0489	protein tyrosine kinase activity
KD35_02175	COG2194	sulfuric ester hydrolase activity
KD35_02180	COG0726	polysaccharide deacetylase
KD35_02265	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KD35_02270	COG4856	YbbR-like protein
KD35_02285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KD35_02290	COG0596	Alpha beta hydrolase
KD35_02310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KD35_02315	COG1506	peptidase
KD35_02315	COG0823	Involved in the tonB-independent uptake of proteins
KD35_02315	COG4946	Tricorn protease homolog
KD35_02350	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_02355	COG2011	ABC-type metal ion transport system permease component
KD35_02360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_02365	COG1464	Belongs to the NlpA lipoprotein family
KD35_02380	COG0277	FAD linked oxidase domain protein
KD35_02385	COG2271	Major facilitator Superfamily
KD35_02395	COG2814	Major facilitator Superfamily
KD35_02410	COG0601	transmembrane transport
KD35_02415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_02420	COG0444	Belongs to the ABC transporter superfamily
KD35_02425	COG4608	Belongs to the ABC transporter superfamily
KD35_02430	COG4166	transmembrane transport
KD35_02440	COG2207	Transcriptional regulator
KD35_02455	COG4166	transmembrane transport
KD35_02460	COG4166	transmembrane transport
KD35_02465	COG0656	L-ascorbic acid biosynthetic process
KD35_02470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_02490	COG4149	molybdate abc transporter
KD35_02495	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_02500	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_02505	COG1910	domain protein
KD35_02520	COG0583	DNA-binding transcription factor activity
KD35_02525	COG0697	spore germination
KD35_02535	COG0204	Acyl-transferase
KD35_02545	COG1609	Transcriptional regulator
KD35_02555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_02570	COG0084	hydrolase, TatD family'
KD35_02575	COG5298	Protein conserved in bacteria
KD35_02600	COG0488	(ABC) transporter
KD35_02615	COG0747	negative chemotaxis
KD35_02620	COG0601	transmembrane transport
KD35_02630	COG0444	Belongs to the ABC transporter superfamily
KD35_02635	COG4608	Belongs to the ABC transporter superfamily
KD35_02675	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KD35_02680	COG0179	Fumarylacetoacetate (FAA) hydrolase
KD35_02690	COG2814	Major facilitator Superfamily
KD35_02705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KD35_02715	COG4294	response to UV
KD35_02720	COG0457	Tetratricopeptide repeat
KD35_02720	COG0705	Rhomboid family
KD35_02730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KD35_02735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KD35_02740	COG0864	Transcriptional regulator
KD35_02745	COG2337	Toxic component of a toxin-antitoxin (TA) module
KD35_02750	COG2183	response to ionizing radiation
KD35_02845	COG0802	atpase or kinase
KD35_02850	COG1214	PFAM Peptidase M22, glycoprotease
KD35_02855	COG0456	acetyltransferase
KD35_02860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KD35_02865	COG0488	(ABC) transporter
KD35_02880	COG1266	CAAX protease self-immunity
KD35_02900	COG2252	PERMEase
KD35_02910	COG5002	protein histidine kinase activity
KD35_02940	COG2226	methyltransferase
KD35_02980	COG1968	undecaprenyl-diphosphatase activity
KD35_02995	COG2205	protein histidine kinase activity
KD35_03000	COG0745	RESPONSE REGULATOR receiver
KD35_03020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KD35_03025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KD35_03030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KD35_03040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KD35_03055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KD35_03065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KD35_03075	COG0151	Belongs to the GarS family
KD35_03100	COG0210	DNA helicase
KD35_03110	COG4851	CamS sex pheromone cAM373 precursor
KD35_03130	COG1335	isochorismatase
KD35_03135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_03140	COG2011	ABC-type metal ion transport system permease component
KD35_03145	COG1464	Belongs to the NlpA lipoprotein family
KD35_03165	COG1846	Transcriptional regulator
KD35_03190	COG1597	lipid kinase activity
KD35_03195	COG0546	phosphoglycolate phosphatase activity
KD35_03200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KD35_03210	COG1012	belongs to the aldehyde dehydrogenase family
KD35_03215	COG2076	Multidrug Resistance protein
KD35_03220	COG2309	aminopeptidase activity
KD35_03235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_03240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KD35_03245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KD35_03255	COG4807	Protein conserved in bacteria
KD35_03285	COG1473	amidohydrolase
KD35_03300	COG0450	alkyl hydroperoxide reductase
KD35_03305	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KD35_03315	COG0235	Class ii aldolase
KD35_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_03330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_03350	COG0166	Belongs to the GPI family
KD35_03385	COG5002	protein histidine kinase activity
KD35_03405	COG3541	Predicted nucleotidyltransferase
KD35_03410	COG2814	Major facilitator Superfamily
KD35_03415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_03415	COG0723	plastoquinol--plastocyanin reductase activity
KD35_03425	COG0765	amino acid transport
KD35_03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_03445	COG0840	transmembrane signaling receptor activity
KD35_03450	COG0840	transmembrane signaling receptor activity
KD35_03455	COG0366	Alpha amylase catalytic
KD35_03460	COG1263	PTS System
KD35_03460	COG2190	(PTS) system
KD35_03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_03490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KD35_03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_03515	COG1116	anion transmembrane transporter activity
KD35_03520	COG0488	(ABC) transporter
KD35_03565	COG2270	Major facilitator Superfamily
KD35_03580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_03595	COG2310	stress, protein
KD35_03600	COG2310	stress, protein
KD35_03605	COG2310	stress, protein
KD35_03610	COG0861	Integral membrane protein TerC family
KD35_03620	COG3853	Toxic anion resistance protein (TelA)
KD35_03635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KD35_03645	COG1295	ribonuclease BN
KD35_03650	COG2217	Heavy metal translocating P-type atpase
KD35_03655	COG0697	spore germination
KD35_03675	COG0586	Pfam SNARE associated Golgi protein
KD35_03690	COG3871	stress protein (general stress protein 26)
KD35_03695	COG0387	Pfam Sodium calcium exchanger
KD35_03705	COG0535	radical SAM domain protein
KD35_03730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KD35_03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KD35_03740	COG0582	viral genome integration into host DNA
KD35_03745	COG1396	sequence-specific DNA binding
KD35_03760	COG1396	sequence-specific DNA binding
KD35_03795	COG1484	DNA-dependent DNA replication
KD35_03890	COG0582	viral genome integration into host DNA
KD35_03895	COG0582	viral genome integration into host DNA
KD35_04020	COG0101	tRNA pseudouridine synthase activity
KD35_04030	COG3829	transcription factor binding
KD35_04040	COG0833	amino acid
KD35_04045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_04075	COG2066	Belongs to the glutaminase family
KD35_04080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_04080	COG1263	PTS System
KD35_04085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_04100	COG0463	Glycosyl transferase, family 2
KD35_04115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_04115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KD35_04135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KD35_04155	COG1228	amidohydrolase
KD35_04160	COG1090	epimerase
KD35_04190	COG1988	membrane-bound metal-dependent
KD35_04195	COG1194	a g-specific adenine glycosylase
KD35_04220	COG1132	(ABC) transporter
KD35_04225	COG4129	membrane
KD35_04230	COG0069	glutamate synthase activity
KD35_04230	COG0067	glutamate synthase
KD35_04230	COG0070	glutamate synthase
KD35_04240	COG4555	ABC transporter
KD35_04260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KD35_04265	COG0735	belongs to the Fur family
KD35_04380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KD35_04385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KD35_04395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KD35_04405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KD35_04420	COG2766	serine protein kinase
KD35_04445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KD35_04455	COG1585	Membrane protein implicated in regulation of membrane protease activity
KD35_04460	COG2268	Band 7 protein
KD35_04470	COG3290	protein histidine kinase activity
KD35_04475	COG4565	transcriptional regulatory protein
KD35_04480	COG2851	Citrate transporter
KD35_04500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KD35_04505	COG3842	ATPase activity
KD35_04510	COG1175	transmembrane transport
KD35_04515	COG0395	ABC-type sugar transport system, permease component
KD35_04525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KD35_04530	COG0745	RESPONSE REGULATOR receiver
KD35_04535	COG5002	protein histidine kinase activity
KD35_04545	COG4990	cell redox homeostasis
KD35_04555	COG3290	protein histidine kinase activity
KD35_04560	COG4565	transcriptional regulatory protein
KD35_04565	COG3493	citrate carrier protein
KD35_04570	COG0281	malic enzyme
KD35_04585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_04595	COG5002	protein histidine kinase activity
KD35_04600	COG0745	RESPONSE REGULATOR receiver
KD35_04610	COG0454	-acetyltransferase
KD35_04610	COG0456	acetyltransferase
KD35_04615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KD35_04620	COG3383	formate dehydrogenase (NAD+) activity
KD35_04625	COG2427	Protein of unknown function (DUF1641)
KD35_04640	COG0531	amino acid
KD35_04645	COG0640	Transcriptional regulator
KD35_04650	COG2217	Heavy metal translocating P-type atpase
KD35_04655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KD35_04665	COG3227	Zinc metalloprotease (Elastase)
KD35_04685	COG2720	vancomycin resistance protein
KD35_04690	COG1316	TRANSCRIPTIONal
KD35_04695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_04700	COG0346	lactoylglutathione lyase activity
KD35_04705	COG1253	flavin adenine dinucleotide binding
KD35_04710	COG1027	Aspartate ammonia-lyase
KD35_04715	COG1620	l-lactate permease
KD35_04730	COG3104	oligopeptide transport
KD35_04735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_04745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_04755	COG2226	methyltransferase
KD35_04760	COG0156	8-amino-7-oxononanoate synthase activity
KD35_04765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_04775	COG4548	von Willebrand factor, type A
KD35_04780	COG0714	Associated with various cellular activities
KD35_04785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_04805	COG0531	amino acid
KD35_04810	COG2188	Transcriptional regulator
KD35_04815	COG1263	PTS System
KD35_04815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_04820	COG0366	Alpha amylase catalytic
KD35_04835	COG0697	spore germination
KD35_04845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_04850	COG1115	amino acid carrier protein
KD35_04855	COG1126	abc transporter atp-binding protein
KD35_04860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_04865	COG0765	amino acid transport
KD35_04870	COG0765	amino acid transport
KD35_04875	COG0833	amino acid
KD35_04900	COG2378	regulation of single-species biofilm formation
KD35_04905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KD35_04910	COG5002	protein histidine kinase activity
KD35_04925	COG0659	secondary active sulfate transmembrane transporter activity
KD35_04940	COG0747	negative chemotaxis
KD35_04950	COG0601	transmembrane transport
KD35_04955	COG4608	Belongs to the ABC transporter superfamily
KD35_04965	COG2271	Major facilitator Superfamily
KD35_04970	COG1846	Transcriptional regulator
KD35_04975	COG0477	Major facilitator Superfamily
KD35_04980	COG0477	Major facilitator Superfamily
KD35_04985	COG1609	Transcriptional regulator
KD35_04990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KD35_05000	COG1129	ABC transporter
KD35_05005	COG1172	Belongs to the binding-protein-dependent transport system permease family
KD35_05010	COG1879	ABC-type sugar transport system periplasmic component
KD35_05015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KD35_05035	COG1063	alcohol dehydrogenase
KD35_05050	COG3568	Endonuclease Exonuclease Phosphatase
KD35_05075	COG1968	undecaprenyl-diphosphatase activity
KD35_05080	COG0840	transmembrane signaling receptor activity
KD35_05085	COG3584	3D domain protein
KD35_05085	COG1388	LysM domain
KD35_05090	COG1476	TRANSCRIPTIONal
KD35_05105	COG3104	oligopeptide transport
KD35_05110	COG1114	Component of the transport system for branched-chain amino acids
KD35_05125	COG1113	amino acid transport
KD35_05130	COG2252	PERMEase
KD35_05155	COG0475	glutathione-regulated potassium exporter activity
KD35_05155	COG0569	domain protein
KD35_05170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KD35_05175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KD35_05180	COG0833	amino acid
KD35_05185	COG4990	cell redox homeostasis
KD35_05200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_05205	COG0697	spore germination
KD35_05210	COG0531	amino acid
KD35_05225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_05230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_05235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KD35_05235	COG1918	ferrous iron import across plasma membrane
KD35_05240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KD35_05245	COG0573	inorganic phosphate transmembrane transporter activity
KD35_05250	COG0581	inorganic phosphate transmembrane transporter activity
KD35_05260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KD35_05380	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KD35_05405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KD35_05410	COG1116	anion transmembrane transporter activity
KD35_05415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_05420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_05425	COG0352	thiamine-phosphate diphosphorylase activity
KD35_05430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_05435	COG2104	thiamine diphosphate biosynthetic process
KD35_05445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_05450	COG0351	phosphomethylpyrimidine kinase
KD35_05495	COG2205	protein histidine kinase activity
KD35_05500	COG2814	Major facilitator Superfamily
KD35_05505	COG1846	Transcriptional regulator
KD35_05520	COG2252	PERMEase
KD35_05525	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_05540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KD35_05550	COG1263	PTS System
KD35_05550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_05555	COG1609	Transcriptional regulator
KD35_05565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_05570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KD35_05610	COG0778	Nitroreductase
KD35_05615	COG2719	SpoVR family
KD35_05640	COG0446	pyridine nucleotide-disulphide oxidoreductase
KD35_05645	COG1937	Protein conserved in bacteria
KD35_05650	COG0425	Belongs to the sulfur carrier protein TusA family
KD35_05650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_05655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_05655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_05660	COG0425	Belongs to the sulfur carrier protein TusA family
KD35_05665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_05675	COG2210	Belongs to the sulfur carrier protein TusA family
KD35_05680	COG0730	response to heat
KD35_05690	COG1316	TRANSCRIPTIONal
KD35_05695	COG0604	alcohol dehydrogenase
KD35_05700	COG1283	sodium-dependent phosphate transmembrane transporter activity
KD35_05715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_05715	COG3711	transcriptional antiterminator
KD35_05720	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_05725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_05745	COG3584	3D domain protein
KD35_05745	COG1388	LysM domain
KD35_05750	COG0577	efflux transmembrane transporter activity
KD35_05755	COG1136	(ABC) transporter
KD35_05765	COG5522	Integral membrane protein (intg_mem_TP0381)
KD35_05780	COG1114	Component of the transport system for branched-chain amino acids
KD35_05785	COG3546	catalase activity
KD35_05820	COG0586	Pfam SNARE associated Golgi protein
KD35_05855	COG0531	amino acid
KD35_05860	COG0475	glutathione-regulated potassium exporter activity
KD35_05870	COG1737	Transcriptional regulator
KD35_05880	COG1263	PTS System
KD35_05880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_05890	COG2259	Doxx family
KD35_05905	COG0697	spore germination
KD35_05910	COG1522	sequence-specific DNA binding
KD35_05920	COG2076	Multidrug Resistance protein
KD35_05925	COG2076	Multidrug Resistance protein
KD35_05930	COG1309	transcriptional regulator
KD35_05935	COG2814	Major facilitator Superfamily
KD35_05940	COG1733	regulation of RNA biosynthetic process
KD35_05950	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_05955	COG4533	DNA binding
KD35_05960	COG2211	Major facilitator Superfamily
KD35_05970	COG0693	protein deglycase activity
KD35_05975	COG0753	catalase activity
KD35_05975	COG0693	protein deglycase activity
KD35_05985	COG0531	amino acid
KD35_05990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KD35_06000	COG1012	belongs to the aldehyde dehydrogenase family
KD35_06010	COG1132	(ABC) transporter
KD35_06020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_06025	COG0765	amino acid transport
KD35_06030	COG1126	abc transporter atp-binding protein
KD35_06045	COG0189	ligase activity
KD35_06075	COG0028	Belongs to the TPP enzyme family
KD35_06080	COG3527	Alpha-acetolactate decarboxylase
KD35_06095	COG0561	phosphatase activity
KD35_06110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KD35_06125	COG0659	secondary active sulfate transmembrane transporter activity
KD35_06145	COG0653	protein targeting
KD35_06150	COG2244	polysaccharide biosynthetic process
KD35_06160	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_06165	COG4196	transglutaminase domain protein
KD35_06180	COG1696	Membrane protein involved in D-alanine export
KD35_06195	COG1024	Enoyl-CoA hydratase
KD35_06215	COG1363	Peptidase, m42
KD35_06235	COG3938	Belongs to the proline racemase family
KD35_06275	COG0601	transmembrane transport
KD35_06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_06290	COG4608	Belongs to the ABC transporter superfamily
KD35_06320	COG0477	Major facilitator Superfamily
KD35_06325	COG3290	protein histidine kinase activity
KD35_06330	COG4565	transcriptional regulatory protein
KD35_06335	COG3181	Tripartite tricarboxylate transporter family receptor
KD35_06365	COG0789	Transcriptional regulator
KD35_06365	COG4978	Transcriptional regulator
KD35_06380	COG0305	Participates in initiation and elongation during chromosome replication
KD35_06420	COG0477	Major facilitator Superfamily
KD35_06470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KD35_06470	COG3320	Male sterility
KD35_06495	COG1183	phosphatidylcholine synthase activity
KD35_06515	COG2376	Dihydroxyacetone kinase
KD35_06525	COG2376	Dihydroxyacetone kinase
KD35_06530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_06535	COG1959	2 iron, 2 sulfur cluster binding
KD35_06560	COG2770	Histidine kinase
KD35_06560	COG3437	response regulator, receiver
KD35_06610	COG3237	CsbD-like
KD35_06635	COG1191	sigma factor activity
KD35_06645	COG2208	phosphoserine phosphatase activity
KD35_06650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KD35_06655	COG2205	protein histidine kinase activity
KD35_06655	COG0784	Response regulator, receiver
KD35_06655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_06655	COG2198	Histidine kinase
KD35_06680	COG0393	Putative heavy-metal-binding
KD35_06715	COG0420	3'-5' exonuclease activity
KD35_06720	COG4717	serine-type aminopeptidase activity
KD35_06740	COG1309	transcriptional regulator
KD35_06745	COG2814	Major facilitator Superfamily
KD35_06750	COG0346	lactoylglutathione lyase activity
KD35_06755	COG0346	lactoylglutathione lyase activity
KD35_06760	COG0457	Tetratricopeptide repeat
KD35_06765	COG2267	carboxylic ester hydrolase activity
KD35_06785	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KD35_06790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KD35_06800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KD35_06840	COG0477	Major facilitator Superfamily
KD35_06845	COG0477	Major facilitator Superfamily
KD35_06855	COG3973	AAA domain
KD35_06860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_06885	COG4980	gas vesicle protein
KD35_06890	COG0537	adenosine 5'-monophosphoramidase activity
KD35_06895	COG1131	(ABC) transporter
KD35_06900	COG4473	ABC transporter
KD35_06910	COG1309	transcriptional regulator
KD35_06920	COG3402	PFAM membrane-flanked domain
KD35_06930	COG3428	Bacterial PH domain
KD35_06975	COG3402	PFAM membrane-flanked domain
KD35_06980	COG3428	Bacterial PH domain
KD35_06985	COG2329	Antibiotic biosynthesis monooxygenase
KD35_06990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_06995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KD35_07040	COG1309	transcriptional regulator
KD35_07045	COG1511	domain protein
KD35_07070	COG1609	Transcriptional regulator
KD35_07080	COG1234	tRNA 3'-trailer cleavage
KD35_07085	COG0095	Lipoate-protein ligase
KD35_07095	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_07125	COG3209	COG3209 Rhs family protein
KD35_07170	COG1408	metallophosphoesterase
KD35_07175	COG1078	dGTPase activity
KD35_07185	COG1595	DNA-templated transcription, initiation
KD35_07190	COG2207	Transcriptional regulator
KD35_07190	COG3708	Transcriptional regulator
KD35_07205	COG2205	protein histidine kinase activity
KD35_07210	COG0745	RESPONSE REGULATOR receiver
KD35_07235	COG0501	Belongs to the peptidase M48B family
KD35_07240	COG0840	transmembrane signaling receptor activity
KD35_07245	COG0697	spore germination
KD35_07260	COG0497	DNA recombination
KD35_07265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KD35_07270	COG2224	Isocitrate lyase
KD35_07280	COG1278	Cold shock
KD35_07295	COG4903	ComK protein
KD35_07300	COG0398	Pfam SNARE associated Golgi protein
KD35_07310	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KD35_07315	COG1074	ATP-dependent DNA helicase activity
KD35_07360	COG0179	Fumarylacetoacetate (FAA) hydrolase
KD35_07385	COG0367	asparagine synthase
KD35_07395	COG0753	catalase activity
KD35_07400	COG0004	ammonium transporteR
KD35_07425	COG2996	Protein conserved in bacteria
KD35_07435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_07445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_07460	COG0561	phosphatase activity
KD35_07475	COG0542	response to heat
KD35_07485	COG2267	carboxylic ester hydrolase activity
KD35_07500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_07505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KD35_07510	COG5504	Zn-dependent protease
KD35_07520	COG0180	Tryptophanyl-tRNA synthetase
KD35_07530	COG4166	transmembrane transport
KD35_07535	COG0601	transmembrane transport
KD35_07540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KD35_07545	COG0444	Belongs to the ABC transporter superfamily
KD35_07550	COG4608	Belongs to the ABC transporter superfamily
KD35_07555	COG0534	Mate efflux family protein
KD35_07560	COG4166	transmembrane transport
KD35_07575	COG1393	Belongs to the ArsC family
KD35_07580	COG0861	Integral membrane protein TerC family
KD35_07585	COG4862	establishment of competence for transformation
KD35_07590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_07600	COG1164	Oligoendopeptidase f
KD35_07615	COG2346	COG2346, Truncated hemoglobins
KD35_07620	COG4116	CYTH
KD35_07630	COG2357	RelA SpoT domain protein
KD35_07635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KD35_07640	COG0564	pseudouridine synthase activity
KD35_07655	COG0772	Belongs to the SEDS family
KD35_07660	COG1216	Glycosyl transferase, family 2
KD35_07680	COG0457	Tetratricopeptide repeat
KD35_07680	COG0463	Glycosyl transferase, family 2
KD35_07700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KD35_07715	COG1091	dTDP-4-dehydrorhamnose reductase activity
KD35_07760	COG2153	protein acetylation
KD35_07765	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KD35_07770	COG2382	esterase
KD35_07785	COG5492	domain, Protein
KD35_07790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_07805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KD35_07805	COG0512	Glutamine amidotransferase of anthranilate synthase
KD35_07840	COG1620	l-lactate permease
KD35_07845	COG5634	Uncharacterized conserved protein (DUF2278)
KD35_07895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_07905	COG1476	TRANSCRIPTIONal
KD35_07965	COG2226	methyltransferase
KD35_08000	COG1012	belongs to the aldehyde dehydrogenase family
KD35_08005	COG3842	ATPase activity
KD35_08010	COG1176	ABC-type spermidine putrescine transport system, permease component I
KD35_08015	COG1177	transmembrane transport
KD35_08020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KD35_08030	COG2409	Drug exporters of the RND superfamily
KD35_08040	COG0564	pseudouridine synthase activity
KD35_08050	COG2340	Cysteine-rich secretory protein family
KD35_08055	COG0247	lactate metabolic process
KD35_08060	COG0277	FAD linked oxidase domain protein
KD35_08065	COG3835	regulator
KD35_08075	COG0745	RESPONSE REGULATOR receiver
KD35_08080	COG5002	protein histidine kinase activity
KD35_08085	COG2186	Transcriptional regulator
KD35_08105	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KD35_08115	COG2116	formate transmembrane transporter activity
KD35_08120	COG0861	Integral membrane protein TerC family
KD35_08125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_08135	COG2030	dehydratase
KD35_08155	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_08160	COG3243	poly(R)-hydroxyalkanoic acid synthase
KD35_08170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_08185	COG1840	ABC-type Fe3 transport system, periplasmic component
KD35_08200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KD35_08215	COG1349	DNA-binding transcription factor activity
KD35_08240	COG2861	carbohydrate metabolic process
KD35_08250	COG3852	Histidine kinase
KD35_08255	COG1846	Transcriptional regulator
KD35_08265	COG2318	DinB family
KD35_08275	COG5002	protein histidine kinase activity
KD35_08285	COG0720	synthase
KD35_08300	COG4873	Protein conserved in bacteria
KD35_08335	COG1780	Probably involved in ribonucleotide reductase function
KD35_08355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KD35_08360	COG1725	Transcriptional regulator
KD35_08365	COG1131	(ABC) transporter
KD35_08375	COG1131	(ABC) transporter
KD35_08380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_08395	COG1522	sequence-specific DNA binding
KD35_08405	COG1335	isochorismatase
KD35_08415	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_08420	COG2070	2-Nitropropane dioxygenase
KD35_08425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KD35_08435	COG1696	Membrane protein involved in D-alanine export
KD35_08460	COG0716	FMN binding
KD35_08475	COG3173	Aminoglycoside phosphotransferase
KD35_08495	COG0534	Mate efflux family protein
KD35_08500	COG1968	undecaprenyl-diphosphatase activity
KD35_08515	COG1846	Transcriptional regulator
KD35_08525	COG1301	dicarboxylic acid transport
KD35_08530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KD35_08535	COG4709	membrane
KD35_08540	COG3874	Sporulation protein YtfJ
KD35_08570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_08575	COG0028	Belongs to the TPP enzyme family
KD35_08580	COG0440	acetolactate synthase activity
KD35_08585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KD35_08595	COG0473	3-isopropylmalate dehydrogenase activity
KD35_08620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KD35_08655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KD35_08670	COG1183	phosphatidylcholine synthase activity
KD35_08675	COG1368	sulfuric ester hydrolase activity
KD35_08685	COG0019	diaminopimelate decarboxylase activity
KD35_08705	COG0529	Catalyzes the synthesis of activated sulfate
KD35_08710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KD35_08730	COG1648	precorrin-2 dehydrogenase activity
KD35_08740	COG0733	neurotransmitter:sodium symporter activity
KD35_08760	COG1757	Na H antiporter
KD35_08775	COG4758	membrane
KD35_08780	COG4585	Histidine kinase
KD35_08785	COG2197	response regulator
KD35_08795	COG1114	Component of the transport system for branched-chain amino acids
KD35_08805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KD35_08830	COG1017	nitric oxide dioxygenase activity
KD35_08830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KD35_08850	COG0730	response to heat
KD35_08855	COG0306	phosphate transporter
KD35_08860	COG1392	Phosphate transport regulator
KD35_08865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_08880	COG3852	Histidine kinase
KD35_08885	COG1801	Protein of unknown function DUF72
KD35_08895	COG0582	viral genome integration into host DNA
KD35_08900	COG5002	protein histidine kinase activity
KD35_08920	COG0392	lysyltransferase activity
KD35_08920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KD35_08935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_08940	COG1686	Belongs to the peptidase S11 family
KD35_08945	COG2715	membrane protein required for spore maturation
KD35_08950	COG0700	Nucleoside recognition
KD35_08955	COG1187	pseudouridine synthase activity
KD35_08965	COG1333	cytochrome c biogenesis protein
KD35_08970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KD35_08975	COG0745	RESPONSE REGULATOR receiver
KD35_08980	COG5002	protein histidine kinase activity
KD35_08985	COG2096	Adenosyltransferase
KD35_09000	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KD35_09005	COG1141	Ferredoxin
KD35_09010	COG4955	Helix-turn-helix domain
KD35_09015	COG0514	ATP-dependent DNA helicase (RecQ)
KD35_09020	COG1266	CAAX protease self-immunity
KD35_09040	COG4862	establishment of competence for transformation
KD35_09045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KD35_09065	COG0492	ferredoxin-NADP+ reductase activity
KD35_09070	COG0252	asparaginase activity
KD35_09140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_09155	COG0142	geranyltranstransferase activity
KD35_09165	COG0142	geranyltranstransferase activity
KD35_09170	COG0105	UTP biosynthetic process
KD35_09185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KD35_09190	COG0457	Tetratricopeptide repeat
KD35_09210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KD35_09220	COG4347	Protein of unknown function (DUF1405)
KD35_09235	COG2738	Putative neutral zinc metallopeptidase
KD35_09245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_09250	COG1694	Mazg nucleotide pyrophosphohydrolase
KD35_09265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_09270	COG0438	transferase activity, transferring glycosyl groups
KD35_09310	COG1199	ATP-dependent helicase activity
KD35_09310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KD35_09330	COG3935	DnaD domain protein
KD35_09335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KD35_09385	COG4474	Belongs to the UPF0398 family
KD35_09395	COG0116	Belongs to the methyltransferase superfamily
KD35_09405	COG1199	ATP-dependent helicase activity
KD35_09410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KD35_09420	COG3173	Aminoglycoside phosphotransferase
KD35_09425	COG0024	Methionine aminopeptidase
KD35_09435	COG2233	PERMEase
KD35_09440	COG2311	Membrane
KD35_09445	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_09455	COG0456	acetyltransferase
KD35_09480	COG0754	glutathionylspermidine amidase activity
KD35_09495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_09520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KD35_09535	COG1215	transferase activity, transferring glycosyl groups
KD35_09540	COG0438	transferase activity, transferring glycosyl groups
KD35_09555	COG0454	-acetyltransferase
KD35_09575	COG0328	RNA-DNA hybrid ribonuclease activity
KD35_09615	COG1280	lysine exporter protein (LysE YggA)
KD35_09630	COG3162	membrane
KD35_09640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_09650	COG0475	glutathione-regulated potassium exporter activity
KD35_09655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_09660	COG4978	Transcriptional regulator
KD35_09660	COG0789	Transcriptional regulator
KD35_09670	COG2323	membrane
KD35_09675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KD35_09730	COG1923	regulation of RNA biosynthetic process
KD35_09740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KD35_09745	COG1360	Flagellar Motor Protein
KD35_09750	COG2201	protein-glutamate methylesterase activity
KD35_09760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_09760	COG1776	CheC inhibitor of MCP methylation
KD35_09775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KD35_09795	COG1256	bacterial-type flagellum assembly
KD35_09800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KD35_09825	COG1815	bacterial-type flagellum-dependent cell motility
KD35_09830	COG1558	bacterial-type flagellum-dependent cell motility
KD35_09835	COG1677	Flagellar hook-basal body complex protein FliE
KD35_09840	COG1766	The M ring may be actively involved in energy transduction
KD35_09850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_09860	COG1157	protein secretion by the type III secretion system
KD35_09900	COG0784	Response regulator, receiver
KD35_09900	COG0835	chemotaxis
KD35_09910	COG0463	Glycosyl transferase, family 2
KD35_09940	COG0463	Glycosyl transferase, family 2
KD35_09940	COG0457	Tetratricopeptide repeat
KD35_09965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KD35_09970	COG0741	lytic transglycosylase activity
KD35_09985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KD35_09985	COG1776	CheC inhibitor of MCP methylation
KD35_09995	COG1338	Plays a role in the flagellum-specific transport system
KD35_10000	COG1987	bacterial-type flagellum assembly
KD35_10010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KD35_10015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KD35_10020	COG1419	protein localization to endoplasmic reticulum
KD35_10025	COG4786	Flagellar basal body rod
KD35_10030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_10055	COG1309	transcriptional regulator
KD35_10075	COG2329	Antibiotic biosynthesis monooxygenase
KD35_10105	COG3842	ATPase activity
KD35_10110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KD35_10115	COG1177	transmembrane transport
KD35_10120	COG1234	tRNA 3'-trailer cleavage
KD35_10145	COG1686	Belongs to the peptidase S11 family
KD35_10155	COG0406	alpha-ribazole phosphatase activity
KD35_10200	COG2733	membrane
KD35_10235	COG1131	(ABC) transporter
KD35_10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_10255	COG0528	UMP kinase activity
KD35_10265	COG1027	Aspartate ammonia-lyase
KD35_10270	COG0281	malic enzyme
KD35_10275	COG4191	Histidine kinase
KD35_10280	COG0784	Response regulator, receiver
KD35_10285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_10345	COG1051	belongs to the nudix hydrolase family
KD35_10350	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_10375	COG1966	Carbon starvation protein
KD35_10390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_10400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KD35_10410	COG4166	transmembrane transport
KD35_10415	COG2223	nitrite transmembrane transporter activity
KD35_10420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_10435	COG2244	polysaccharide biosynthetic process
KD35_10440	COG0733	neurotransmitter:sodium symporter activity
KD35_10450	COG5566	PFAM Mor transcription activator
KD35_10455	COG2323	membrane
KD35_10470	COG2084	Dehydrogenase
KD35_10485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KD35_10495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_10500	COG0028	Belongs to the TPP enzyme family
KD35_10505	COG0440	acetolactate synthase activity
KD35_10510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KD35_10520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KD35_10545	COG2814	Major facilitator Superfamily
KD35_10550	COG3384	dioxygenase
KD35_10560	COG3279	Response regulator of the LytR AlgR family
KD35_10565	COG0427	acetyl-CoA hydrolase
KD35_10585	COG1073	alpha beta
KD35_10590	COG4166	transmembrane transport
KD35_10620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_10640	COG1914	H( )-stimulated, divalent metal cation uptake system
KD35_10655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KD35_10690	COG2390	Transcriptional regulator
KD35_10700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_10705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KD35_10720	COG4224	UPF0291 protein
KD35_10740	COG0006	proline dipeptidase activity
KD35_10745	COG2132	Multicopper oxidase
KD35_10775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_10790	COG1276	copper resistance
KD35_10790	COG2372	response to copper ion
KD35_10795	COG4549	nuclear export factor GLE1
KD35_10805	COG0697	spore germination
KD35_10810	COG0583	DNA-binding transcription factor activity
KD35_10815	COG1959	2 iron, 2 sulfur cluster binding
KD35_10820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KD35_10825	COG0778	Nitroreductase
KD35_10840	COG0628	permease
KD35_10845	COG0039	L-malate dehydrogenase activity
KD35_10850	COG1231	oxidoreductase activity
KD35_10855	COG0523	cobalamin synthesis protein
KD35_10870	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_10875	COG2030	dehydratase
KD35_10880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_10890	COG0411	ABC transporter
KD35_10910	COG0583	DNA-binding transcription factor activity
KD35_10930	COG1846	Transcriptional regulator
KD35_10940	COG1271	oxidase subunit
KD35_10945	COG1294	oxidase, subunit
KD35_10950	COG4988	ABC transporter
KD35_10955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KD35_10975	COG1686	Belongs to the peptidase S11 family
KD35_10990	COG0791	NLP P60 protein
KD35_10990	COG1388	LysM domain
KD35_11000	COG1132	(ABC) transporter
KD35_11005	COG1132	(ABC) transporter
KD35_11010	COG0745	RESPONSE REGULATOR receiver
KD35_11015	COG5002	protein histidine kinase activity
KD35_11025	COG0300	oxidoreductase activity
KD35_11040	COG0726	polysaccharide deacetylase
KD35_11060	COG0460	homoserine dehydrogenase
KD35_11085	COG1316	TRANSCRIPTIONal
KD35_11095	COG0745	RESPONSE REGULATOR receiver
KD35_11100	COG5002	protein histidine kinase activity
KD35_11105	COG0726	polysaccharide deacetylase
KD35_11115	COG1285	pathogenesis
KD35_11120	COG1247	-acetyltransferase
KD35_11130	COG4264	IucA IucC family
KD35_11135	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_11150	COG1082	Xylose isomerase domain protein TIM barrel
KD35_11165	COG1279	arginine transmembrane transporter activity
KD35_11175	COG1752	Esterase of the alpha-beta hydrolase superfamily
KD35_11215	COG2002	toxin-antitoxin pair type II binding
KD35_11220	COG1404	Belongs to the peptidase S8 family
KD35_11225	COG0640	Transcriptional regulator
KD35_11230	COG0667	Aldo Keto reductase
KD35_11235	COG2814	Major facilitator Superfamily
KD35_11260	COG0840	transmembrane signaling receptor activity
KD35_11280	COG3949	Membrane
KD35_11285	COG0783	Belongs to the Dps family
KD35_11300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_11310	COG1231	oxidoreductase activity
KD35_11320	COG4989	oxidoreductase activity
KD35_11325	COG0523	cobalamin synthesis protein
KD35_11330	COG0456	acetyltransferase
KD35_11395	COG0803	Belongs to the bacterial solute-binding protein 9 family
KD35_11395	COG3443	Belongs to the bacterial solute-binding protein 9 family
KD35_11405	COG0702	epimerase
KD35_11415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KD35_11425	COG4166	transmembrane transport
KD35_11440	COG0406	alpha-ribazole phosphatase activity
KD35_11450	COG5337	Spore coat protein CotH
KD35_11455	COG1051	belongs to the nudix hydrolase family
KD35_11460	COG0586	Pfam SNARE associated Golgi protein
KD35_11465	COG2244	polysaccharide biosynthetic process
KD35_11475	COG0701	Predicted permease
KD35_11480	COG3689	TIGRFAM TIGR03943 family protein
KD35_11485	COG1607	acyl-coa hydrolase
KD35_11490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KD35_11505	COG0702	epimerase
KD35_11510	COG2839	Protein conserved in bacteria
KD35_11515	COG1253	flavin adenine dinucleotide binding
KD35_11530	COG1114	Component of the transport system for branched-chain amino acids
KD35_11535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_11555	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_11565	COG1876	peptidase activity
KD35_11575	COG0154	amidase activity
KD35_11580	COG2211	Major facilitator Superfamily
KD35_11600	COG0561	phosphatase activity
KD35_11610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KD35_11630	COG1819	glycosyl
KD35_11635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_11665	COG0456	acetyltransferase
KD35_11715	COG3874	Sporulation protein YtfJ
KD35_11740	COG2226	methyltransferase
KD35_11760	COG1082	Xylose isomerase domain protein TIM barrel
KD35_11765	COG0346	lactoylglutathione lyase activity
KD35_11775	COG0604	alcohol dehydrogenase
KD35_11780	COG1595	DNA-templated transcription, initiation
KD35_11805	COG0386	Belongs to the glutathione peroxidase family
KD35_11810	COG1305	Transglutaminase-like
KD35_11815	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KD35_11820	COG0714	Associated with various cellular activities
KD35_11835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KD35_11840	COG1140	nitrate reductase beta subunit
KD35_11845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KD35_11850	COG2181	nitrate reductase activity
KD35_11870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KD35_11875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KD35_11880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_11885	COG0303	'Molybdopterin
KD35_11890	COG0314	molybdopterin synthase activity
KD35_11900	COG2223	nitrite transmembrane transporter activity
KD35_11915	COG1648	precorrin-2 dehydrogenase activity
KD35_11925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KD35_11925	COG1587	Uroporphyrinogen-III synthase
KD35_11930	COG2146	nitrite reductase [NAD(P)H] activity
KD35_11935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KD35_11940	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KD35_11975	COG2359	stage V sporulation protein S
KD35_11990	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_12005	COG1418	mRNA catabolic process
KD35_12010	COG0488	(ABC) transporter
KD35_12025	COG0629	single-stranded DNA binding
KD35_12040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KD35_12045	COG1413	lyase activity
KD35_12060	COG2136	Putative SAM-dependent methyltransferase
KD35_12060	COG2521	methyltransferase
KD35_12065	COG0018	arginyl-trna synthetase
KD35_12090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KD35_12105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KD35_12110	COG0017	Asparaginyl-tRNA synthetase
KD35_12130	COG1674	ftsk spoiiie
KD35_12225	COG1929	Belongs to the glycerate kinase type-1 family
KD35_12230	COG0471	metal ion transport
KD35_12235	COG0745	RESPONSE REGULATOR receiver
KD35_12240	COG5002	protein histidine kinase activity
KD35_12240	COG3850	Histidine kinase
KD35_12255	COG0733	neurotransmitter:sodium symporter activity
KD35_12280	COG2610	gluconate transmembrane transporter activity
KD35_12285	COG1454	alcohol dehydrogenase
KD35_12290	COG1794	racemase activity, acting on amino acids and derivatives
KD35_12300	COG0456	acetyltransferase
KD35_12315	COG1131	(ABC) transporter
KD35_12320	COG4473	ABC transporter
KD35_12330	COG0546	phosphoglycolate phosphatase activity
KD35_12350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_12365	COG0768	penicillin binding
KD35_12370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KD35_12375	COG0204	Acyl-transferase
KD35_12380	COG1272	protein, Hemolysin III
KD35_12390	COG0805	protein transport
KD35_12400	COG1307	EDD domain protein, DegV family
KD35_12405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KD35_12410	COG1999	signal sequence binding
KD35_12415	COG0071	Belongs to the small heat shock protein (HSP20) family
KD35_12420	COG0367	asparagine synthase
KD35_12440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_12445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KD35_12480	COG0668	transmembrane transport
KD35_12485	COG4585	Histidine kinase
KD35_12485	COG2203	Gaf domain
KD35_12490	COG2197	response regulator
KD35_12500	COG1737	Transcriptional regulator
KD35_12505	COG1064	alcohol dehydrogenase
KD35_12535	COG1070	Carbohydrate kinase
KD35_12570	COG1125	glycine betaine transport
KD35_12570	COG0517	IMP dehydrogenase activity
KD35_12575	COG1174	glycine betaine transport
KD35_12610	COG1253	flavin adenine dinucleotide binding
KD35_12615	COG1012	belongs to the aldehyde dehydrogenase family
KD35_12620	COG5506	Protein of unknown function (DUF1694)
KD35_12635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_12640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KD35_12645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KD35_12650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_12655	COG0456	acetyltransferase
KD35_12660	COG3829	transcription factor binding
KD35_12665	COG1509	lysine 2,3-aminomutase activity
KD35_12705	COG4326	sporulation control protein
KD35_12710	COG0671	phosphoesterase, PA-phosphatase related
KD35_12715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KD35_12720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_12750	COG1787	Restriction endonuclease
KD35_12750	COG1715	Restriction endonuclease
KD35_12840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KD35_12880	COG4499	WXG100 protein secretion system (Wss), protein YukC
KD35_12880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KD35_12885	COG2814	Major facilitator Superfamily
KD35_12890	COG4841	protein insertion into membrane
KD35_12895	COG0372	Belongs to the citrate synthase family
KD35_12900	COG2079	MmgE PrpD family protein
KD35_12905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KD35_12910	COG1960	acyl-CoA dehydrogenase activity
KD35_12915	COG2084	Dehydrogenase
KD35_12920	COG1012	belongs to the aldehyde dehydrogenase family
KD35_12925	COG1280	lysine exporter protein (LysE YggA)
KD35_12930	COG1024	Enoyl-CoA hydratase
KD35_12945	COG0420	3'-5' exonuclease activity
KD35_12950	COG0419	ATPase involved in DNA repair
KD35_12980	COG2223	nitrite transmembrane transporter activity
KD35_12985	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_12990	COG1169	isochorismate synthase
KD35_12995	COG1021	2,3-dihydroxybenzoate-AMP ligase
KD35_13000	COG3433	isochorismatase activity
KD35_13000	COG1535	isochorismatase
KD35_13005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KD35_13010	COG3251	PFAM MbtH domain protein
KD35_13015	COG2814	Major facilitator Superfamily
KD35_13030	COG0776	regulation of translation
KD35_13040	COG2318	DinB family
KD35_13050	COG1115	amino acid carrier protein
KD35_13070	COG2329	Antibiotic biosynthesis monooxygenase
KD35_13075	COG1187	pseudouridine synthase activity
KD35_13080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_13095	COG0596	Alpha beta hydrolase
KD35_13100	COG2814	Major facilitator Superfamily
KD35_13120	COG2226	methyltransferase
KD35_13165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_13200	COG1247	-acetyltransferase
KD35_13240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_13250	COG1278	Cold shock
KD35_13265	COG0010	Belongs to the arginase family
KD35_13270	COG0561	phosphatase activity
KD35_13315	COG0583	DNA-binding transcription factor activity
KD35_13320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KD35_13335	COG0583	DNA-binding transcription factor activity
KD35_13340	COG2258	MOSC domain
KD35_13355	COG1132	(ABC) transporter
KD35_13360	COG1132	(ABC) transporter
KD35_13380	COG1396	sequence-specific DNA binding
KD35_13410	COG1595	DNA-templated transcription, initiation
KD35_13435	COG1649	PFAM Uncharacterised BCR, COG1649
KD35_13460	COG2971	BadF BadG BcrA BcrD
KD35_13465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_13470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KD35_13490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_13520	COG1309	transcriptional regulator
KD35_13535	COG0577	efflux transmembrane transporter activity
KD35_13535	COG1136	(ABC) transporter
KD35_13540	COG3615	Tellurite resistance protein tehB
KD35_13540	COG0500	methyltransferase
KD35_13550	COG2226	methyltransferase
KD35_13555	COG3961	Belongs to the TPP enzyme family
KD35_13560	COG1846	Transcriptional regulator
KD35_13600	COG2195	Cleaves the N-terminal amino acid of tripeptides
KD35_13615	COG1595	DNA-templated transcription, initiation
KD35_13625	COG0768	penicillin binding
KD35_13635	COG2367	Beta-lactamase
KD35_13640	COG0671	phosphoesterase, PA-phosphatase related
KD35_13645	COG1609	Transcriptional regulator
KD35_13650	COG2814	Major facilitator Superfamily
KD35_13655	COG0673	inositol 2-dehydrogenase activity
KD35_13665	COG1012	belongs to the aldehyde dehydrogenase family
KD35_13685	COG3718	enzyme involved in inositol metabolism
KD35_13700	COG0737	Belongs to the 5'-nucleotidase family
KD35_13715	COG0457	Tetratricopeptide repeat
KD35_13720	COG1476	TRANSCRIPTIONal
KD35_13735	COG1876	peptidase activity
KD35_13755	COG1309	transcriptional regulator
KD35_13775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_13785	COG1252	NADH dehydrogenase
KD35_13790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_13805	COG1131	(ABC) transporter
KD35_13815	COG1309	transcriptional regulator
KD35_13830	COG1960	acyl-CoA dehydrogenase activity
KD35_13835	COG0439	Biotin carboxylase
KD35_13840	COG0511	ligase activity, forming carbon-carbon bonds
KD35_13845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KD35_13850	COG1024	Enoyl-CoA hydratase
KD35_13855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KD35_13860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_13870	COG1247	-acetyltransferase
KD35_13875	COG0572	uridine kinase
KD35_13885	COG2318	DinB family
KD35_13890	COG1686	Belongs to the peptidase S11 family
KD35_13915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KD35_13955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_13955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_13970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_13980	COG2814	Major facilitator Superfamily
KD35_14000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_14020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_14035	COG1063	alcohol dehydrogenase
KD35_14050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_14055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_14070	COG3773	Cell wall hydrolase
KD35_14080	COG0745	RESPONSE REGULATOR receiver
KD35_14110	COG1136	(ABC) transporter
KD35_14135	COG0460	homoserine dehydrogenase
KD35_14140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_14150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KD35_14225	COG2124	cytochrome p450
KD35_14260	COG0561	phosphatase activity
KD35_14270	COG5002	protein histidine kinase activity
KD35_14280	COG1819	glycosyl
KD35_14285	COG1794	racemase activity, acting on amino acids and derivatives
KD35_14295	COG1122	ATPase activity
KD35_14305	COG2205	protein histidine kinase activity
KD35_14320	COG0604	alcohol dehydrogenase
KD35_14335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_14370	COG0693	protein deglycase activity
KD35_14400	COG2814	Major facilitator Superfamily
KD35_14415	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_14435	COG0697	spore germination
KD35_14470	COG2223	nitrite transmembrane transporter activity
KD35_14485	COG2816	NAD+ diphosphatase activity
KD35_14490	COG0592	DNA-directed DNA polymerase activity
KD35_14495	COG1051	belongs to the nudix hydrolase family
KD35_14530	COG3878	Protein conserved in bacteria
KD35_14560	COG4667	esterase of the alpha-beta hydrolase superfamily
KD35_14585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KD35_14600	COG0322	excinuclease ABC activity
KD35_14640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_14665	COG1011	Hydrolase
KD35_14685	COG0076	glutamate decarboxylase activity
KD35_14700	COG1523	belongs to the glycosyl hydrolase 13 family
KD35_14705	COG3227	Zinc metalloprotease (Elastase)
KD35_14725	COG0201	protein transport
KD35_14735	COG0697	spore germination
KD35_14740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_14770	COG4129	membrane
KD35_14775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_14790	COG2959	enzyme of heme biosynthesis
KD35_14795	COG3409	Peptidoglycan-binding domain 1 protein
KD35_14795	COG3773	Cell wall hydrolase
KD35_14810	COG3483	tryptophan 2,3-dioxygenase activity
KD35_14815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KD35_14820	COG3844	kynureninase activity
KD35_14825	COG1309	transcriptional regulator
KD35_14855	COG3284	Transcriptional regulator
KD35_14875	COG1349	DNA-binding transcription factor activity
KD35_14895	COG1959	2 iron, 2 sulfur cluster binding
KD35_14910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KD35_14915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_14920	COG0022	dehydrogenase e1 component
KD35_14925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_14935	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_14940	COG0456	acetyltransferase
KD35_14940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_14975	COG4176	ABC-type proline glycine betaine transport system permease component
KD35_14980	COG0517	IMP dehydrogenase activity
KD35_14980	COG4175	Glycine betaine
KD35_14990	COG0740	serine-type endopeptidase activity
KD35_15005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KD35_15010	COG2153	protein acetylation
KD35_15015	COG3397	chitin binding
KD35_15030	COG2205	protein histidine kinase activity
KD35_15060	COG0658	competence protein
KD35_15060	COG2333	competence protein COMEC
KD35_15110	COG3973	AAA domain
KD35_15125	COG2105	PFAM AIG2 family protein
KD35_15130	COG0514	ATP-dependent DNA helicase (RecQ)
KD35_15160	COG4637	Psort location Cytoplasmic, score
KD35_15185	COG3397	chitin binding
KD35_15195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KD35_15200	COG1115	amino acid carrier protein
KD35_15205	COG1012	belongs to the aldehyde dehydrogenase family
KD35_15210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KD35_15220	COG3938	Belongs to the proline racemase family
KD35_15225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KD35_15265	COG0586	Pfam SNARE associated Golgi protein
KD35_15280	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KD35_15285	COG0519	Catalyzes the synthesis of GMP from XMP
KD35_15290	COG4166	transmembrane transport
KD35_15300	COG4948	Mandelate Racemase Muconate Lactonizing
KD35_15340	COG2936	dipeptidyl-peptidase activity
KD35_15345	COG5002	protein histidine kinase activity
KD35_15350	COG0745	RESPONSE REGULATOR receiver
KD35_15390	COG1307	EDD domain protein, DegV family
KD35_15410	COG2814	Major facilitator Superfamily
KD35_15420	COG1664	Polymer-forming cytoskeletal
KD35_15425	COG0789	Transcriptional regulator
KD35_15430	COG4533	DNA binding
KD35_15435	COG0477	Major facilitator Superfamily
KD35_15435	COG2814	Major facilitator Superfamily
KD35_15455	COG2261	transglycosylase associated protein
KD35_15470	COG2226	methyltransferase
KD35_15505	COG0436	Aminotransferase
KD35_15510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KD35_15515	COG5146	pantothenate kinase activity
KD35_15535	COG1131	(ABC) transporter
KD35_15585	COG0628	permease
KD35_15600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_15605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_15610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_15615	COG1116	anion transmembrane transporter activity
KD35_15655	COG2746	aminoglycoside 3-N-acetyltransferase activity
KD35_15680	COG0697	spore germination
KD35_15685	COG2318	DinB family
KD35_15705	COG4912	Dna alkylation repair
KD35_15715	COG0726	polysaccharide deacetylase
KD35_15725	COG0861	Integral membrane protein TerC family
KD35_15730	COG1368	sulfuric ester hydrolase activity
KD35_15735	COG0488	(ABC) transporter
KD35_15745	COG1033	growth of symbiont in host cell
KD35_15745	COG2409	Drug exporters of the RND superfamily
KD35_15750	COG2409	Drug exporters of the RND superfamily
KD35_15750	COG1033	growth of symbiont in host cell
KD35_15755	COG2409	Drug exporters of the RND superfamily
KD35_15755	COG1033	growth of symbiont in host cell
KD35_15760	COG1309	transcriptional regulator
KD35_15775	COG0287	Prephenate dehydrogenase
KD35_15780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KD35_15785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KD35_15790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KD35_15790	COG1605	Chorismate mutase
KD35_15825	COG3584	3D domain protein
KD35_15825	COG1388	LysM domain
KD35_15835	COG1595	DNA-templated transcription, initiation
KD35_15860	COG1879	ABC-type sugar transport system periplasmic component
KD35_15870	COG1172	Belongs to the binding-protein-dependent transport system permease family
KD35_15880	COG2390	Transcriptional regulator
KD35_15915	COG2329	Antibiotic biosynthesis monooxygenase
KD35_15935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_15945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KD35_15950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_15955	COG4187	Peptidase family M20/M25/M40
KD35_15960	COG1414	Transcriptional regulator
KD35_15965	COG0833	amino acid
KD35_15970	COG1690	Belongs to the RtcB family
KD35_15975	COG3239	Fatty acid desaturase
KD35_15980	COG1785	Belongs to the alkaline phosphatase family
KD35_15990	COG3655	Transcriptional regulator
KD35_16005	COG4377	Putative membrane peptidase family (DUF2324)
KD35_16015	COG3279	Response regulator of the LytR AlgR family
KD35_16025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_16030	COG0346	lactoylglutathione lyase activity
KD35_16050	COG0714	Associated with various cellular activities
KD35_16100	COG0463	Glycosyl transferase, family 2
KD35_16110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KD35_16115	COG0753	catalase activity
KD35_16125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KD35_16150	COG0714	Associated with various cellular activities
KD35_16160	COG0778	Nitroreductase
KD35_16165	COG1846	Transcriptional regulator
KD35_16200	COG1725	Transcriptional regulator
KD35_16210	COG0577	efflux transmembrane transporter activity
KD35_16210	COG1136	(ABC) transporter
KD35_16235	COG2207	Transcriptional regulator
KD35_16240	COG0456	acetyltransferase
KD35_16260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_16280	COG0642	Histidine kinase
KD35_16285	COG0745	RESPONSE REGULATOR receiver
KD35_16290	COG0596	Alpha beta hydrolase
KD35_16320	COG0730	response to heat
KD35_16330	COG0833	amino acid
KD35_16340	COG4335	DNA alkylation repair
KD35_16390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KD35_16425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KD35_16430	COG1414	Transcriptional regulator
KD35_16445	COG0860	N-Acetylmuramoyl-L-alanine amidase
KD35_16450	COG0640	Transcriptional regulator
KD35_16460	COG1960	acyl-CoA dehydrogenase activity
KD35_16495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KD35_16510	COG0574	Belongs to the PEP-utilizing enzyme family
KD35_16510	COG3848	Pyruvate phosphate dikinase
KD35_16515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_16530	COG5577	PFAM Coat F domain
KD35_16535	COG3403	YqcI/YcgG family
KD35_16540	COG1280	lysine exporter protein (LysE YggA)
KD35_16575	COG1063	alcohol dehydrogenase
KD35_16590	COG1027	Aspartate ammonia-lyase
KD35_16595	COG0252	asparaginase activity
KD35_16600	COG1396	sequence-specific DNA binding
KD35_16610	COG0322	excinuclease ABC activity
KD35_16615	COG0531	amino acid
KD35_16620	COG1114	Component of the transport system for branched-chain amino acids
KD35_16625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_16635	COG0281	malic enzyme
KD35_16655	COG0531	amino acid
KD35_16660	COG0697	spore germination
KD35_16665	COG0784	Response regulator, receiver
KD35_16675	COG2066	Belongs to the glutaminase family
KD35_16680	COG1115	amino acid carrier protein
KD35_16705	COG0737	Belongs to the 5'-nucleotidase family
KD35_16710	COG0753	catalase activity
KD35_16715	COG2267	carboxylic ester hydrolase activity
KD35_16720	COG1335	isochorismatase
KD35_16745	COG0583	DNA-binding transcription factor activity
KD35_16790	COG0415	Belongs to the DNA photolyase family
KD35_16795	COG0288	reversible hydration of carbon dioxide
KD35_16805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KD35_16810	COG5609	conserved protein (DUF2294)
KD35_16820	COG1575	Belongs to the MenA family. Type 1 subfamily
KD35_16825	COG2267	carboxylic ester hydrolase activity
KD35_16830	COG0803	Belongs to the bacterial solute-binding protein 9 family
KD35_16835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KD35_16840	COG1121	(ABC) transporter
KD35_16870	COG0798	PFAM Bile acid sodium symporter
KD35_16875	COG0346	lactoylglutathione lyase activity
KD35_16880	COG0640	Transcriptional regulator
KD35_16895	COG0443	Heat shock 70 kDa protein
KD35_16910	COG1522	sequence-specific DNA binding
KD35_16925	COG0346	lactoylglutathione lyase activity
KD35_16950	COG2169	Transcriptional regulator
KD35_16995	COG2814	Major facilitator Superfamily
KD35_17020	COG0745	RESPONSE REGULATOR receiver
KD35_17025	COG5002	protein histidine kinase activity
KD35_17025	COG3850	Histidine kinase
KD35_17055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KD35_17080	COG1476	TRANSCRIPTIONal
KD35_17095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_17100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KD35_17110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_17115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KD35_17130	COG1136	(ABC) transporter
KD35_17135	COG0577	efflux transmembrane transporter activity
KD35_17155	COG5002	protein histidine kinase activity
KD35_17155	COG3850	Histidine kinase
KD35_17165	COG2364	Membrane
KD35_17170	COG1846	Transcriptional regulator
KD35_17180	COG2808	Putative FMN-binding domain
KD35_17185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_17190	COG2271	Major facilitator Superfamily
KD35_17195	COG1556	Lactate utilization protein
KD35_17200	COG1139	Iron-sulfur cluster binding protein
KD35_17210	COG0583	DNA-binding transcription factor activity
KD35_17220	COG1619	proteins homologs of microcin C7 resistance protein MccF
KD35_17245	COG0738	Major facilitator superfamily
KD35_17250	COG0673	inositol 2-dehydrogenase activity
KD35_17255	COG0561	phosphatase activity
KD35_17265	COG1609	Transcriptional regulator
KD35_17270	COG0457	Tetratricopeptide repeat
KD35_17290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KD35_17320	COG0534	Mate efflux family protein
KD35_17335	COG2814	Major facilitator Superfamily
KD35_17340	COG1309	transcriptional regulator
KD35_17355	COG0814	amino acid
KD35_17360	COG1760	l-serine dehydratase
KD35_17365	COG1760	l-serine dehydratase
KD35_17375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KD35_17380	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KD35_17390	COG1335	isochorismatase
KD35_17395	COG1522	sequence-specific DNA binding
KD35_17400	COG0531	amino acid
KD35_17415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KD35_17435	COG1595	DNA-templated transcription, initiation
KD35_17450	COG0662	Cupin 2, conserved barrel domain protein
KD35_17460	COG2207	Transcriptional regulator
KD35_17460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_17515	COG0477	Major facilitator Superfamily
KD35_17525	COG1846	Transcriptional regulator
KD35_17530	COG2814	Major facilitator Superfamily
KD35_17545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KD35_17550	COG1131	(ABC) transporter
KD35_17570	COG2076	Multidrug Resistance protein
KD35_17575	COG1309	transcriptional regulator
KD35_17590	COG2031	fatty acid transporter
KD35_17600	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_17630	COG1122	ATPase activity
KD35_17635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KD35_17650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KD35_17655	COG1288	antiporter activity
KD35_17660	COG2356	endonuclease I
KD35_17675	COG3620	sequence-specific DNA binding
KD35_17680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_17685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KD35_17690	COG0124	histidyl-tRNA synthetase
KD35_17705	COG1733	regulation of RNA biosynthetic process
KD35_17710	COG0778	Nitroreductase
KD35_17730	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_17740	COG1131	(ABC) transporter
KD35_17765	COG1011	Hydrolase
KD35_17800	COG0346	lactoylglutathione lyase activity
KD35_17805	COG1940	carbohydrate kinase activity
KD35_17810	COG0738	Major facilitator superfamily
KD35_17815	COG0110	maltose O-acetyltransferase activity
KD35_17825	COG1136	(ABC) transporter
KD35_17830	COG0180	Tryptophanyl-tRNA synthetase
KD35_17835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KD35_17840	COG0628	permease
KD35_17860	COG2226	methyltransferase
KD35_17870	COG0477	Major facilitator Superfamily
KD35_17900	COG1253	flavin adenine dinucleotide binding
KD35_17905	COG0789	Transcriptional regulator
KD35_17910	COG0697	spore germination
KD35_17915	COG1357	PFAM Pentapeptide repeats (8 copies)
KD35_17920	COG3813	Protein conserved in bacteria
KD35_17925	COG2706	6-phosphogluconolactonase activity
KD35_17930	COG1070	Carbohydrate kinase
KD35_17940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KD35_17945	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KD35_17955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KD35_17960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KD35_17965	COG0604	alcohol dehydrogenase
KD35_17970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KD35_17990	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_18015	COG0656	L-ascorbic acid biosynthetic process
KD35_18020	COG2814	Major facilitator Superfamily
KD35_18035	COG0346	lactoylglutathione lyase activity
KD35_18040	COG0814	amino acid
KD35_18065	COG1393	Belongs to the ArsC family
KD35_18075	COG1733	regulation of RNA biosynthetic process
KD35_18080	COG2188	Transcriptional regulator
KD35_18090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KD35_18095	COG1733	regulation of RNA biosynthetic process
KD35_18100	COG1733	regulation of RNA biosynthetic process
KD35_18115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_18135	COG0384	phenazine biosynthesis protein PhzF
KD35_18145	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_18155	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_18165	COG1733	regulation of RNA biosynthetic process
KD35_18200	COG1191	sigma factor activity
KD35_18215	COG1309	transcriptional regulator
KD35_18235	COG3152	Membrane
KD35_18260	COG1151	hydroxylamine reductase activity
KD35_18270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_18275	COG3409	Peptidoglycan-binding domain 1 protein
KD35_18275	COG3757	hydrolase, family 25
KD35_18310	COG2072	flavoprotein involved in K transport
KD35_18345	COG0604	alcohol dehydrogenase
KD35_18350	COG1113	amino acid transport
KD35_18355	COG2814	Major facilitator Superfamily
KD35_18390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_18395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_18415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_18435	COG3739	integral membrane protein
KD35_18440	COG0384	phenazine biosynthesis protein PhzF
KD35_18470	COG0583	DNA-binding transcription factor activity
KD35_18490	COG1193	negative regulation of DNA recombination
KD35_18505	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KD35_18515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KD35_18545	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_18570	COG0640	Transcriptional regulator
KD35_18575	COG0604	alcohol dehydrogenase
KD35_18595	COG2808	Putative FMN-binding domain
KD35_18600	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_18610	COG0385	Bile acid
KD35_18615	COG0277	FAD linked oxidase domain protein
KD35_18650	COG1216	Glycosyl transferase, family 2
KD35_18655	COG1024	Enoyl-CoA hydratase
KD35_18665	COG1285	pathogenesis
KD35_18675	COG2514	catechol 2,3-dioxygenase activity
KD35_18680	COG2720	vancomycin resistance protein
KD35_18710	COG1278	Cold shock
KD35_18720	COG0716	FMN binding
KD35_18750	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_18760	COG0165	Argininosuccinate lyase
KD35_18775	COG4145	pantothenate transmembrane transporter activity
KD35_18785	COG1012	belongs to the aldehyde dehydrogenase family
KD35_18790	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_18800	COG1657	PFAM Prenyltransferase squalene oxidase
KD35_18805	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KD35_18810	COG2962	Rard protein
KD35_18815	COG3326	Membrane
KD35_18830	COG0489	protein tyrosine kinase activity
KD35_18840	COG0314	molybdopterin synthase activity
KD35_18845	COG0303	'Molybdopterin
KD35_18850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_18855	COG2116	formate transmembrane transporter activity
KD35_18865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KD35_18870	COG5609	conserved protein (DUF2294)
KD35_18875	COG2427	Protein of unknown function (DUF1641)
KD35_18880	COG3383	formate dehydrogenase (NAD+) activity
KD35_18890	COG0697	spore germination
KD35_18930	COG2226	methyltransferase
KD35_18935	COG4166	transmembrane transport
KD35_18940	COG4166	transmembrane transport
KD35_18945	COG4166	transmembrane transport
KD35_18950	COG1301	dicarboxylic acid transport
KD35_18955	COG1316	TRANSCRIPTIONal
KD35_18965	COG1595	DNA-templated transcription, initiation
KD35_18990	COG1131	(ABC) transporter
KD35_19000	COG0673	inositol 2-dehydrogenase activity
KD35_19005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KD35_19010	COG0187	DNA topoisomerase II activity
KD35_19020	COG1832	CoA-binding protein
KD35_19025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_19030	COG0745	RESPONSE REGULATOR receiver
KD35_19045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KD35_19050	COG4841	protein insertion into membrane
KD35_19055	COG0824	Thioesterase
KD35_19085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_19095	COG2274	protein secretion by the type I secretion system
KD35_19100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KD35_19110	COG0726	polysaccharide deacetylase
KD35_19130	COG2211	Major facilitator Superfamily
KD35_19140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_19155	COG0183	Belongs to the thiolase family
KD35_19160	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_19165	COG1268	BioY protein
KD35_19170	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_19215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_19225	COG5002	protein histidine kinase activity
KD35_19230	COG0400	carboxylic ester hydrolase activity
KD35_19235	COG0346	lactoylglutathione lyase activity
KD35_19240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KD35_19245	COG0069	glutamate synthase activity
KD35_19250	COG1902	pentaerythritol trinitrate reductase activity
KD35_19255	COG1329	Transcriptional regulator
KD35_19260	COG0010	Belongs to the arginase family
KD35_19285	COG2226	methyltransferase
KD35_19340	COG4846	Membrane protein involved in cytochrome C biogenesis
KD35_19345	COG0785	Cytochrome C biogenesis protein
KD35_19355	COG0583	DNA-binding transcription factor activity
KD35_19360	COG1380	Effector of murein hydrolase LrgA
KD35_19365	COG1346	cytolysis
KD35_19380	COG0730	response to heat
KD35_19390	COG3409	Peptidoglycan-binding domain 1 protein
KD35_19390	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_19405	COG1132	(ABC) transporter
KD35_19410	COG1132	(ABC) transporter
KD35_19445	COG3639	organic phosphonate transmembrane transporter activity
KD35_19450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KD35_19465	COG0737	Belongs to the 5'-nucleotidase family
KD35_19475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KD35_19495	COG1695	Transcriptional regulator
KD35_19530	COG3409	Peptidoglycan-binding domain 1 protein
KD35_19530	COG5632	N-Acetylmuramoyl-L-alanine amidase
KD35_19530	COG1388	LysM domain
KD35_19535	COG4824	toxin secretion phage lysis holin
KD35_19695	COG1595	DNA-templated transcription, initiation
KD35_19740	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KD35_19820	COG1396	sequence-specific DNA binding
KD35_19845	COG0174	glutamine synthetase
KD35_19850	COG0789	Transcriptional regulator
KD35_19855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KD35_19865	COG2860	membrane
KD35_19870	COG0464	growth
KD35_19900	COG3584	3D domain protein
KD35_19900	COG1388	LysM domain
KD35_19905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KD35_19905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KD35_19905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_19910	COG1105	Belongs to the carbohydrate kinase PfkB family
KD35_19915	COG1349	DNA-binding transcription factor activity
KD35_19925	COG2322	membrane
KD35_19940	COG1113	amino acid transport
KD35_19950	COG1408	metallophosphoesterase
KD35_19955	COG2116	formate transmembrane transporter activity
KD35_19965	COG2217	Heavy metal translocating P-type atpase
KD35_19970	COG2608	mercury ion transmembrane transporter activity
KD35_19975	COG1937	Protein conserved in bacteria
KD35_19985	COG2819	hydrolase of the alpha beta superfamily
KD35_19990	COG1120	ATPase activity
KD35_19995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_20000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KD35_20005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_20015	COG0708	Exodeoxyribonuclease III
KD35_20020	COG2169	Transcriptional regulator
KD35_20025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KD35_20030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KD35_20040	COG2364	Membrane
KD35_20055	COG2267	carboxylic ester hydrolase activity
KD35_20060	COG0346	lactoylglutathione lyase activity
KD35_20065	COG5001	Diguanylate cyclase
KD35_20065	COG3300	MHYT domain
KD35_20085	COG1346	cytolysis
KD35_20090	COG1380	Effector of murein hydrolase LrgA
KD35_20095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KD35_20100	COG0596	Alpha beta hydrolase
KD35_20100	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_20105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KD35_20120	COG1404	Belongs to the peptidase S8 family
KD35_20125	COG3773	Cell wall hydrolase
KD35_20130	COG0562	UDP-galactopyranose mutase
KD35_20135	COG1368	sulfuric ester hydrolase activity
KD35_20140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KD35_20150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KD35_20195	COG4550	Control of competence regulator ComK, YlbF/YmcA
KD35_20200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KD35_20205	COG1013	pyruvate-flavodoxin oxidoreductase activity
KD35_20210	COG0674	pyruvate-flavodoxin oxidoreductase activity
KD35_20210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KD35_20220	COG2359	stage V sporulation protein S
KD35_20225	COG1692	metallophosphoesterase
KD35_20250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KD35_20255	COG1426	Protein conserved in bacteria
KD35_20270	COG0300	oxidoreductase activity
KD35_20275	COG0612	Peptidase, M16
KD35_20280	COG0612	Peptidase, M16
KD35_20310	COG2188	Transcriptional regulator
KD35_20315	COG1674	ftsk spoiiie
KD35_20325	COG0740	serine-type endopeptidase activity
KD35_20330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_20345	COG0527	aspartate kinase activity
KD35_20350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KD35_20355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KD35_20360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KD35_20365	COG1873	PFAM PRC-barrel domain
KD35_20370	COG0612	Peptidase, M16
KD35_20375	COG0726	polysaccharide deacetylase
KD35_20390	COG0196	riboflavin kinase activity
KD35_20395	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KD35_20405	COG1550	Protein conserved in bacteria
KD35_20415	COG1358	cellular component organization or biogenesis
KD35_20420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KD35_20425	COG0195	Participates in both transcription termination and antitermination
KD35_20445	COG0750	zinc metalloprotease
KD35_20450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KD35_20455	COG4589	Belongs to the CDS family
KD35_20460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KD35_20470	COG0528	UMP kinase activity
KD35_20500	COG4974	Belongs to the 'phage' integrase family
KD35_20510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KD35_20520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KD35_20560	COG1837	Belongs to the UPF0109 family
KD35_20570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KD35_20580	COG0552	protein localization to endoplasmic reticulum
KD35_20585	COG1196	nuclear chromosome segregation
KD35_20600	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_20605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KD35_20620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KD35_20625	COG1461	Dihydroxyacetone kinase
KD35_20630	COG1302	Protein conserved in bacteria
KD35_20645	COG1564	THIamine pyrophosphokinase
KD35_20650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KD35_20655	COG1162	GTPase activity
KD35_20660	COG2815	serine threonine protein kinase
KD35_20660	COG0515	serine threonine protein kinase
KD35_20665	COG0631	protein serine/threonine phosphatase activity
KD35_20675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KD35_20675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KD35_20685	COG0242	peptide deformylase activity
KD35_20690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KD35_20695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KD35_20705	COG0194	GDP metabolic process
KD35_20715	COG1561	YicC-like family, N-terminal region
KD35_20720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KD35_20730	COG0006	proline dipeptidase activity
KD35_20745	COG3069	C4-dicarboxylate transmembrane transporter activity
KD35_20785	COG0505	Belongs to the CarA family
KD35_20810	COG0564	pseudouridine synthase activity
KD35_20825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KD35_20830	COG3599	regulation of cell shape
KD35_20835	COG2302	S4 RNA-binding domain
KD35_20840	COG0762	integral membrane protein
KD35_20850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KD35_20860	COG1873	PFAM PRC-barrel domain
KD35_20865	COG1191	sigma factor activity
KD35_20870	COG1191	sigma factor activity
KD35_20880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KD35_20885	COG0849	cell division
KD35_20890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KD35_20895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KD35_20900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KD35_20905	COG0772	Belongs to the SEDS family
KD35_20920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KD35_20925	COG0768	penicillin binding
KD35_20935	COG4839	cell division protein FtsL
KD35_20950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KD35_20970	COG1399	metal-binding, possibly nucleic acid-binding protein
KD35_21020	COG4824	toxin secretion phage lysis holin
KD35_21115	COG4626	Terminase
KD35_21115	COG1802	Transcriptional regulator
KD35_21140	COG0582	viral genome integration into host DNA
KD35_21220	COG1191	sigma factor activity
KD35_21245	COG1484	DNA-dependent DNA replication
KD35_21275	COG1396	sequence-specific DNA binding
KD35_21285	COG1396	sequence-specific DNA binding
KD35_21300	COG0582	viral genome integration into host DNA
KD35_21310	COG3480	Lon protease (S16) C-terminal proteolytic domain
KD35_21315	COG1752	Esterase of the alpha-beta hydrolase superfamily
KD35_21320	COG3314	Sporulation integral membrane protein YlbJ
KD35_21330	COG0742	ribosomal rna small subunit methyltransferase
KD35_21345	COG3679	Belongs to the UPF0342 family
KD35_21350	COG0406	alpha-ribazole phosphatase activity
KD35_21365	COG2340	Cysteine-rich secretory protein family
KD35_21380	COG3336	cytochrome c oxidase
KD35_21415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KD35_21420	COG0772	Belongs to the SEDS family
KD35_21425	COG4838	Belongs to the UPF0358 family
KD35_21430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KD35_21435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KD35_21445	COG4896	Protein conserved in bacteria
KD35_21470	COG0483	inositol monophosphate 1-phosphatase activity
KD35_21490	COG1982	Orn Lys Arg decarboxylase major
KD35_21535	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_21540	COG0022	dehydrogenase e1 component
KD35_21545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_21555	COG0242	peptide deformylase activity
KD35_21560	COG0561	phosphatase activity
KD35_21570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KD35_21575	COG0569	domain protein
KD35_21595	COG0583	DNA-binding transcription factor activity
KD35_21600	COG0517	IMP dehydrogenase activity
KD35_21610	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KD35_21620	COG4703	Protein of unknown function (DUF1797)
KD35_21635	COG2200	EAL domain
KD35_21640	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_21645	COG1408	metallophosphoesterase
KD35_21655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KD35_21695	COG2814	Major facilitator Superfamily
KD35_21720	COG3209	COG3209 Rhs family protein
KD35_21730	COG2205	protein histidine kinase activity
KD35_21740	COG0436	Aminotransferase
KD35_21745	COG1609	Transcriptional regulator
KD35_21750	COG3833	ABC-type maltose transport systems, permease component
KD35_21755	COG1175	transmembrane transport
KD35_21760	COG2182	Extracellular solute-binding protein
KD35_21770	COG0366	Alpha amylase catalytic
KD35_21775	COG3842	ATPase activity
KD35_21815	COG0183	Belongs to the thiolase family
KD35_21855	COG1695	Transcriptional regulator
KD35_21860	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_21880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KD35_21885	COG0436	Aminotransferase
KD35_21905	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KD35_21925	COG3706	GGDEF domain
KD35_21930	COG0778	Nitroreductase
KD35_21955	COG1263	PTS System
KD35_21955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KD35_21955	COG2190	(PTS) system
KD35_21960	COG3711	transcriptional antiterminator
KD35_21980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KD35_22010	COG1547	Domain of unknown function (DUF309)
KD35_22015	COG0456	acetyltransferase
KD35_22025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KD35_22030	COG4086	secreted protein
KD35_22035	COG0561	phosphatase activity
KD35_22040	COG0697	spore germination
KD35_22055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_22080	COG0733	neurotransmitter:sodium symporter activity
KD35_22100	COG1686	Belongs to the peptidase S11 family
KD35_22105	COG1725	Transcriptional regulator
KD35_22110	COG1131	(ABC) transporter
KD35_22130	COG1846	Transcriptional regulator
KD35_22145	COG0598	Magnesium transport protein CorA
KD35_22170	COG4974	Belongs to the 'phage' integrase family
KD35_22180	COG0735	belongs to the Fur family
KD35_22185	COG1300	Membrane
KD35_22205	COG0667	Aldo Keto reductase
KD35_22210	COG0656	L-ascorbic acid biosynthetic process
KD35_22215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KD35_22215	COG0456	acetyltransferase
KD35_22225	COG0737	Belongs to the 5'-nucleotidase family
KD35_22225	COG4085	toxin activity
KD35_22225	COG1525	nuclease
KD35_22235	COG0596	Alpha beta hydrolase
KD35_22240	COG2056	Na+-H+ antiporter family
KD35_22245	COG1609	Transcriptional regulator
KD35_22250	COG0456	acetyltransferase
KD35_22255	COG1073	alpha beta
KD35_22270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KD35_22270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KD35_22275	COG0307	riboflavin synthase, alpha
KD35_22295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KD35_22300	COG4106	trans-aconitate 2-methyltransferase activity
KD35_22305	COG2226	methyltransferase
KD35_22305	COG1073	alpha beta
KD35_22310	COG0156	8-amino-7-oxononanoate synthase activity
KD35_22320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KD35_22335	COG0737	Belongs to the 5'-nucleotidase family
KD35_22345	COG1522	sequence-specific DNA binding
KD35_22365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KD35_22375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KD35_22390	COG0300	oxidoreductase activity
KD35_22395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_22405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_22410	COG1760	l-serine dehydratase
KD35_22415	COG1760	l-serine dehydratase
KD35_22435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KD35_22445	COG2195	Cleaves the N-terminal amino acid of tripeptides
KD35_22450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_22465	COG1376	ErfK ybiS ycfS ynhG family protein
KD35_22470	COG4129	membrane
KD35_22475	COG1126	abc transporter atp-binding protein
KD35_22480	COG0765	amino acid transport
KD35_22485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KD35_22510	COG0772	Belongs to the SEDS family
KD35_22520	COG0508	dehydrogenase complex catalyzes the overall conversion of
KD35_22525	COG0022	dehydrogenase e1 component
KD35_22530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KD35_22535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KD35_22545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KD35_22550	COG0280	phosphate acetyltransferase
KD35_22560	COG3829	transcription factor binding
KD35_22560	COG3290	protein histidine kinase activity
KD35_22570	COG0584	glycerophosphoryl diester phosphodiesterase
KD35_22575	COG3093	addiction module antidote protein HigA
KD35_22585	COG0745	RESPONSE REGULATOR receiver
KD35_22590	COG0750	zinc metalloprotease
KD35_22595	COG0497	DNA recombination
KD35_22605	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KD35_22615	COG0142	geranyltranstransferase activity
KD35_22640	COG1302	Protein conserved in bacteria
KD35_22645	COG0439	Biotin carboxylase
KD35_22650	COG0511	ligase activity, forming carbon-carbon bonds
KD35_22695	COG3854	ATPases associated with a variety of cellular activities
KD35_22720	COG0006	proline dipeptidase activity
KD35_22735	COG3872	metal-dependent enzyme
KD35_22745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KD35_22765	COG0095	Lipoate-protein ligase
KD35_22770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_22775	COG1609	Transcriptional regulator
KD35_22785	COG2076	Multidrug Resistance protein
KD35_22790	COG2076	Multidrug Resistance protein
KD35_22830	COG1131	(ABC) transporter
KD35_22835	COG1725	Transcriptional regulator
KD35_22865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KD35_22920	COG4970	Tfp pilus assembly protein FimT
KD35_22930	COG1459	type II secretion system
KD35_22935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KD35_22985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KD35_22990	COG1410	methionine synthase
KD35_22990	COG0646	methionine synthase
KD35_22995	COG0646	methionine synthase
KD35_22995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KD35_23005	COG0626	cystathionine gamma-synthase activity
KD35_23010	COG0626	cystathionine gamma-synthase activity
KD35_23035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_23045	COG1940	carbohydrate kinase activity
KD35_23050	COG4483	Protein conserved in bacteria
KD35_23055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KD35_23065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KD35_23070	COG0704	Plays a role in the regulation of phosphate uptake
KD35_23075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KD35_23080	COG0581	inorganic phosphate transmembrane transporter activity
KD35_23085	COG0573	inorganic phosphate transmembrane transporter activity
KD35_23090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KD35_23100	COG0477	Major facilitator Superfamily
KD35_23105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KD35_23130	COG0735	belongs to the Fur family
KD35_23135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KD35_23140	COG1121	(ABC) transporter
KD35_23145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_23175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KD35_23180	COG2384	SAM-dependent methyltransferase
KD35_23185	COG2010	Cytochrome c
KD35_23190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KD35_23195	COG0358	DNA primase activity
KD35_23215	COG0517	IMP dehydrogenase activity
KD35_23230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KD35_23235	COG0295	cytidine deaminase activity
KD35_23240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KD35_23250	COG1480	7TM receptor with intracellular HD hydrolase
KD35_23255	COG1702	phosphate starvation-inducible protein PhoH
KD35_23275	COG1610	YqeY-like protein
KD35_23285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KD35_23290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KD35_23310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KD35_23320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KD35_23325	COG1733	regulation of RNA biosynthetic process
KD35_23350	COG1466	dna polymerase III delta subunit
KD35_23360	COG0658	competence protein
KD35_23360	COG2333	competence protein COMEC
KD35_23365	COG2131	deaminase
KD35_23370	COG1555	photosystem II stabilization
KD35_23370	COG1596	polysaccharide export
KD35_23375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KD35_23380	COG2226	methyltransferase
KD35_23385	COG0799	negative regulation of ribosome biogenesis
KD35_23390	COG1713	HD superfamily hydrolase involved in NAD metabolism
KD35_23400	COG1534	Rna-binding protein
KD35_23410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KD35_23415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KD35_23430	COG1191	sigma factor activity
KD35_23440	COG1595	DNA-templated transcription, initiation
KD35_23450	COG0778	Nitroreductase
KD35_23455	COG2357	RelA SpoT domain protein
KD35_23465	COG1785	Belongs to the alkaline phosphatase family
KD35_23475	COG2267	carboxylic ester hydrolase activity
KD35_23510	COG1404	Belongs to the peptidase S8 family
KD35_23515	COG3186	Phenylalanine-4-hydroxylase
KD35_23525	COG2514	catechol 2,3-dioxygenase activity
KD35_23530	COG2514	catechol 2,3-dioxygenase activity
KD35_23535	COG2259	Doxx family
KD35_23575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KD35_23585	COG1454	alcohol dehydrogenase
KD35_23585	COG1012	belongs to the aldehyde dehydrogenase family
KD35_23590	COG0626	cystathionine gamma-synthase activity
KD35_23595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KD35_23620	COG0768	penicillin binding
KD35_23650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KD35_23670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KD35_23680	COG0628	permease
KD35_23700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KD35_23710	COG0482	sulfurtransferase activity
KD35_23715	COG1104	cysteine desulfurase activity
KD35_23720	COG1959	2 iron, 2 sulfur cluster binding
KD35_23725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KD35_23735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KD35_23745	COG0124	histidyl-tRNA synthetase
KD35_23760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KD35_23770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KD35_23770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KD35_23775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KD35_23780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KD35_23780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KD35_23790	COG2244	polysaccharide biosynthetic process
KD35_23795	COG2323	membrane
KD35_23805	COG1862	Preprotein translocase
KD35_23835	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KD35_23845	COG0697	spore germination
KD35_23850	COG0697	spore germination
KD35_23855	COG0640	Transcriptional regulator
KD35_23880	COG0157	Belongs to the NadC ModD family
KD35_23885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KD35_23890	COG1104	cysteine desulfurase activity
KD35_23895	COG1827	regulation of RNA biosynthetic process
KD35_23900	COG2258	MOSC domain
KD35_23905	COG0077	Prephenate dehydratase
KD35_23910	COG0577	efflux transmembrane transporter activity
KD35_23915	COG0577	efflux transmembrane transporter activity
KD35_23920	COG1136	(ABC) transporter
KD35_23925	COG5002	protein histidine kinase activity
KD35_23935	COG0745	RESPONSE REGULATOR receiver
KD35_23940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KD35_23945	COG3290	protein histidine kinase activity
KD35_23955	COG2868	ribosomal protein
KD35_23965	COG1530	ribonuclease E activity
KD35_23970	COG1994	Peptidase M50
KD35_23975	COG0739	heme binding
KD35_23980	COG2894	cell division
KD35_23995	COG1792	Involved in formation and maintenance of cell shape
KD35_24000	COG1077	Cell shape determining protein MreB Mrl
KD35_24020	COG0285	dihydrofolate synthase activity
KD35_24025	COG0525	valine-tRNA ligase activity
KD35_24035	COG1388	LysM domain
KD35_24045	COG0113	porphobilinogen synthase activity
KD35_24050	COG1587	Uroporphyrinogen-III synthase
KD35_24060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KD35_24070	COG1846	Transcriptional regulator
KD35_24075	COG1764	response to oxidative stress
KD35_24090	COG1067	ATP-dependent peptidase activity
KD35_24090	COG0470	DNA polymerase III
KD35_24140	COG0622	Phosphoesterase
KD35_24145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KD35_24155	COG5401	PFAM Sporulation and spore germination
KD35_24175	COG1309	transcriptional regulator
KD35_24190	COG2197	response regulator
KD35_24195	COG2233	PERMEase
KD35_24205	COG0402	S-adenosylhomocysteine deaminase activity
KD35_24210	COG0402	S-adenosylhomocysteine deaminase activity
KD35_24230	COG0444	Belongs to the ABC transporter superfamily
KD35_24235	COG4608	Belongs to the ABC transporter superfamily
KD35_24240	COG3275	phosphorelay sensor kinase activity
KD35_24245	COG3279	Response regulator of the LytR AlgR family
KD35_24260	COG1983	PspC domain protein
KD35_24265	COG1396	sequence-specific DNA binding
KD35_24270	COG0697	spore germination
KD35_24280	COG1959	2 iron, 2 sulfur cluster binding
KD35_24285	COG1668	transmembrane transport
KD35_24290	COG4152	abc transporter atp-binding protein
KD35_24295	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KD35_24305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KD35_24310	COG1876	peptidase activity
KD35_24315	COG0824	Thioesterase
KD35_24320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KD35_24325	COG1053	succinate dehydrogenase
KD35_24330	COG2009	succinate dehydrogenase
KD35_24335	COG1719	4-vinyl reductase, 4VR
KD35_24345	COG3118	belongs to the thioredoxin family
KD35_24350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KD35_24355	COG2086	electron transfer activity
KD35_24360	COG1024	Enoyl-CoA hydratase
KD35_24365	COG1309	transcriptional regulator
KD35_24370	COG0318	PFAM AMP-dependent synthetase and ligase
KD35_24390	COG2318	DinB family
KD35_24420	COG1131	(ABC) transporter
KD35_24425	COG2205	protein histidine kinase activity
KD35_24430	COG0745	RESPONSE REGULATOR receiver
KD35_24440	COG4895	conserved protein (DUF2196)
KD35_24445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KD35_24460	COG4509	Sortase family
KD35_24465	COG1120	ATPase activity
KD35_24480	COG5386	Cell surface protein
KD35_24490	COG5386	Cell surface protein
KD35_24495	COG1114	Component of the transport system for branched-chain amino acids
KD35_24500	COG1187	pseudouridine synthase activity
KD35_24515	COG1796	DNA polymerase
KD35_24515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KD35_24520	COG1286	toxin biosynthetic process
KD35_24550	COG0017	Asparaginyl-tRNA synthetase
KD35_24555	COG0072	phenylalanine-tRNA ligase activity
KD35_24555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_24565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KD35_24575	COG1418	mRNA catabolic process
KD35_24600	COG2814	Major facilitator Superfamily
KD35_24605	COG1566	PFAM secretion protein HlyD family protein
KD35_24610	COG1309	transcriptional regulator
KD35_24615	COG1363	Peptidase, m42
KD35_24635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KD35_24640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KD35_24650	COG1484	DNA-dependent DNA replication
KD35_24655	COG3611	Membrane attachment protein
KD35_24665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KD35_24670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KD35_24675	COG0237	dephospho-CoA kinase activity
KD35_24680	COG1971	Probably functions as a manganese efflux pump
KD35_24685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KD35_24690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_24690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KD35_24695	COG5002	protein histidine kinase activity
KD35_24700	COG0745	RESPONSE REGULATOR receiver
KD35_24720	COG0538	isocitrate dehydrogenase activity
KD35_24725	COG0372	Belongs to the citrate synthase family
KD35_24740	COG0628	permease
KD35_24745	COG3030	protein affecting phage T7 exclusion by the F plasmid
KD35_24770	COG1725	Transcriptional regulator
KD35_24775	COG0281	malic enzyme
KD35_24780	COG0587	DNA-directed DNA polymerase activity
KD35_24795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KD35_24815	COG4109	DRTGG domain
KD35_24830	COG0006	proline dipeptidase activity
KD35_24865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_24870	COG0662	Cupin 2, conserved barrel domain protein
KD35_24880	COG1476	TRANSCRIPTIONal
KD35_24895	COG1028	Short-chain dehydrogenase reductase Sdr
KD35_24900	COG0589	response to stress
KD35_24940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_24960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KD35_24965	COG0827	DNA restriction-modification system
KD35_24970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KD35_24975	COG3874	Sporulation protein YtfJ
KD35_24985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KD35_24990	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KD35_25000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_25015	COG1104	cysteine desulfurase activity
KD35_25025	COG0583	DNA-binding transcription factor activity
KD35_25030	COG0697	spore germination
KD35_25040	COG1956	GAF domain-containing protein
KD35_25045	COG0626	cystathionine gamma-synthase activity
KD35_25065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KD35_25075	COG1595	DNA-templated transcription, initiation
KD35_25085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KD35_25090	COG0454	-acetyltransferase
KD35_25095	COG0517	IMP dehydrogenase activity
KD35_25100	COG0123	including yeast histone deacetylase and acetoin utilization protein
KD35_25110	COG0745	RESPONSE REGULATOR receiver
KD35_25120	COG0666	response to abiotic stimulus
KD35_25155	COG1609	Transcriptional regulator
KD35_25165	COG4851	CamS sex pheromone cAM373 precursor
KD35_25170	COG3118	belongs to the thioredoxin family
KD35_25180	COG2309	aminopeptidase activity
KD35_25200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_25215	COG1674	ftsk spoiiie
KD35_25225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_25230	COG4848	Belongs to the UPF0354 family
KD35_25235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_25240	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KD35_25245	COG1363	Peptidase, m42
KD35_25255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_25270	COG0510	thiamine kinase activity
KD35_25275	COG1523	belongs to the glycosyl hydrolase 13 family
KD35_25290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_25295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KD35_25300	COG1349	DNA-binding transcription factor activity
KD35_25305	COG1187	pseudouridine synthase activity
KD35_25310	COG2244	polysaccharide biosynthetic process
KD35_25315	COG2081	HI0933 family
KD35_25320	COG2814	Major facilitator Superfamily
KD35_25330	COG3832	glyoxalase III activity
KD35_25350	COG1329	Transcriptional regulator
KD35_25360	COG4975	Glucose uptake
KD35_25375	COG0314	molybdopterin synthase activity
KD35_25380	COG1763	Mo-molybdopterin cofactor biosynthetic process
KD35_25385	COG0303	'Molybdopterin
KD35_25395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KD35_25420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KD35_25430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KD35_25475	COG2814	Major facilitator Superfamily
KD35_25480	COG0475	glutathione-regulated potassium exporter activity
KD35_25485	COG0490	domain, Protein
KD35_25490	COG0582	viral genome integration into host DNA
KD35_25500	COG1136	(ABC) transporter
KD35_25520	COG1242	4 iron, 4 sulfur cluster binding
KD35_25525	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KD35_25530	COG1131	(ABC) transporter
KD35_25540	COG1794	racemase activity, acting on amino acids and derivatives
KD35_25560	COG2267	carboxylic ester hydrolase activity
KD35_25565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KD35_25570	COG0671	phosphoesterase, PA-phosphatase related
KD35_25575	COG0438	transferase activity, transferring glycosyl groups
KD35_25585	COG0521	Mo-molybdopterin cofactor biosynthetic process
KD35_25640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KD35_25645	COG5002	protein histidine kinase activity
KD35_25650	COG4191	Histidine kinase
KD35_25655	COG2267	carboxylic ester hydrolase activity
KD35_25675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KD35_25680	COG1116	anion transmembrane transporter activity
KD35_25685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KD35_25710	COG0494	nUDIX hydrolase
KD35_25740	COG0288	reversible hydration of carbon dioxide
KD35_25745	COG1271	oxidase subunit
KD35_25750	COG1294	oxidase, subunit
KD35_25770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_25795	COG1842	Phage shock protein A
KD35_25830	COG5002	protein histidine kinase activity
KD35_25835	COG0745	RESPONSE REGULATOR receiver
KD35_25865	COG1597	lipid kinase activity
KD35_25900	COG0586	Pfam SNARE associated Golgi protein
KD35_25910	COG0577	efflux transmembrane transporter activity
KD35_25915	COG1136	(ABC) transporter
KD35_25920	COG2207	Transcriptional regulator
KD35_25920	COG3708	Transcriptional regulator
KD35_25925	COG0745	RESPONSE REGULATOR receiver
KD35_25935	COG0577	efflux transmembrane transporter activity
KD35_25945	COG0577	efflux transmembrane transporter activity
KD35_25950	COG0577	efflux transmembrane transporter activity
KD35_25955	COG1136	(ABC) transporter
KD35_25995	COG3964	amidohydrolase
KD35_26025	COG4948	Mandelate Racemase Muconate Lactonizing
KD35_26035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KD35_26040	COG0596	Alpha beta hydrolase
KD35_26045	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KD35_26050	COG1169	isochorismate synthase
KD35_26055	COG1575	Belongs to the MenA family. Type 1 subfamily
KD35_26060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KD35_26065	COG1278	Cold shock
KD35_26085	COG0058	SHG alpha-glucan phosphorylase activity
KD35_26090	COG0297	glycogen (starch) synthase activity
KD35_26095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KD35_26100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KD35_26110	COG0039	L-malate dehydrogenase activity
KD35_26205	COG0544	peptidyl-prolyl cis-trans isomerase activity
KD35_26240	COG1285	pathogenesis
KD35_26245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KD35_26255	COG0166	Belongs to the GPI family
KD35_26265	COG2155	Conserved Protein
KD35_26270	COG1098	S1 RNA binding domain
KD35_26275	COG0436	Aminotransferase
KD35_26280	COG1522	sequence-specific DNA binding
KD35_26285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KD35_26290	COG2267	carboxylic ester hydrolase activity
KD35_26300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KD35_26320	COG5018	Exonuclease
KD35_26325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KD35_26340	COG0423	glycine-tRNA ligase activity
KD35_26345	COG2050	protein possibly involved in aromatic compounds catabolism
KD35_26355	COG1268	BioY protein
KD35_26365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KD35_26370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KD35_26385	COG3584	3D domain protein
KD35_26400	COG1252	NADH dehydrogenase
KD35_26415	COG3708	Transcriptional regulator
KD35_26430	COG1683	Conserved Protein
KD35_26450	COG0316	Belongs to the HesB IscA family
KD35_26465	COG1252	NADH dehydrogenase
KD35_26480	COG0390	transport system, permease component
KD35_26485	COG2824	Alkylphosphonate utilization operon protein PhnA
KD35_26525	COG4837	Protein of unknown function (DUF1462)
KD35_26530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KD35_26540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KD35_26545	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KD35_26560	COG2249	NAD(P)H dehydrogenase (quinone) activity
KD35_26565	COG0647	UMP catabolic process
KD35_26575	COG2445	Protein of unknown function DUF86
KD35_26580	COG1494	fructose-1,6-bisphosphatase
KD35_26600	COG4470	Protein conserved in bacteria
KD35_26610	COG0789	Transcriptional regulator
KD35_26615	COG4377	Putative membrane peptidase family (DUF2324)
KD35_26640	COG0739	heme binding
KD35_26650	COG3377	Domain of unknown function (DUF1805)
KD35_26655	COG0737	Belongs to the 5'-nucleotidase family
KD35_26665	COG1695	Transcriptional regulator
KD35_26680	COG0719	Fe-S assembly protein
KD35_26685	COG0822	iron-sulfur transferase activity
KD35_26690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KD35_26695	COG0719	Fe-S assembly protein
KD35_26700	COG0396	ATPase activity
KD35_26705	COG1464	Belongs to the NlpA lipoprotein family
KD35_26710	COG1464	Belongs to the NlpA lipoprotein family
KD35_26715	COG2011	ABC-type metal ion transport system permease component
KD35_26720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KD35_26735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KD35_26740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KD35_26750	COG1393	Belongs to the ArsC family
KD35_26800	COG0039	L-malate dehydrogenase activity
KD35_26825	COG1309	transcriptional regulator
KD35_26830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KD35_26835	COG1960	acyl-CoA dehydrogenase activity
KD35_26845	COG0183	Belongs to the thiolase family
KD35_26850	COG1250	3-hydroxyacyl-CoA dehydrogenase
KD35_26850	COG1024	Enoyl-CoA hydratase
KD35_26860	COG1686	Belongs to the peptidase S11 family
KD35_26875	COG0011	TIGRFAM Protein of
KD35_26880	COG0840	transmembrane signaling receptor activity
KD35_26900	COG2814	Major facilitator Superfamily
KD35_26905	COG0531	amino acid
KD35_26915	COG0706	membrane insertase activity
KD35_26925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KD35_26960	COG0586	Pfam SNARE associated Golgi protein
KD35_26970	COG1376	ErfK ybiS ycfS ynhG family protein
KD35_26975	COG0745	RESPONSE REGULATOR receiver
KD35_26980	COG5002	protein histidine kinase activity
KD35_26990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KD35_27005	COG2151	metal-sulfur cluster biosynthetic enzyme
KD35_27010	COG3227	Zinc metalloprotease (Elastase)
KD35_27015	COG1741	Belongs to the pirin family
KD35_27030	COG0475	glutathione-regulated potassium exporter activity
KD35_27035	COG0490	domain, Protein
KD35_27045	COG1115	amino acid carrier protein
KD35_27050	COG0783	Belongs to the Dps family
KD35_27065	COG1611	Belongs to the LOG family
KD35_27080	COG2311	Membrane
KD35_27090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_27095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KD35_27100	COG1115	amino acid carrier protein
KD35_27105	COG1115	amino acid carrier protein
KD35_27110	COG2910	NAD(P)H-binding
KD35_27125	COG0656	L-ascorbic acid biosynthetic process
KD35_27130	COG2814	Major facilitator Superfamily
KD35_27135	COG1733	regulation of RNA biosynthetic process
KD35_27145	COG1252	NADH dehydrogenase
KD35_27150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KD35_27155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KD35_27165	COG0840	transmembrane signaling receptor activity
KD35_27165	COG3290	protein histidine kinase activity
KD35_27175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KD35_27180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KD35_27195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KD35_27200	COG3223	Belongs to the PsiE family
KD35_27245	COG0557	exoribonuclease II activity
KD35_27250	COG1647	Serine aminopeptidase, S33
KD35_27255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KD35_27260	COG1346	cytolysis
KD35_27360	COG4695	Portal protein
KD35_27385	COG4974	Belongs to the 'phage' integrase family
KD35_27395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KD35_27400	COG0149	triose-phosphate isomerase activity
KD35_27410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KD35_27425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KD35_27450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KD35_27465	COG2323	membrane
KD35_27470	COG0740	serine-type endopeptidase activity
KD35_27475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KD35_27485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KD35_27495	COG1051	belongs to the nudix hydrolase family
KD35_27505	COG0492	ferredoxin-NADP+ reductase activity
KD35_27510	COG0457	Tetratricopeptide repeat
KD35_27515	COG0110	maltose O-acetyltransferase activity
KD35_27535	COG1950	PFAM Membrane protein of
KD35_27545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KD35_27550	COG0556	nucleotide-excision repair
KD35_27570	COG0789	Transcriptional regulator
KD35_27595	COG2855	membrane
KD35_27600	COG0583	DNA-binding transcription factor activity
KD35_27610	COG0655	NAD(P)H dehydrogenase (quinone) activity
KD35_27625	COG1132	(ABC) transporter
KD35_27630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KD35_27635	COG0793	Belongs to the peptidase S41A family
KD35_27635	COG3409	Peptidoglycan-binding domain 1 protein
KD35_27640	COG2177	Part of the ABC transporter FtsEX involved in
KD35_27645	COG2884	Cell division ATP-binding protein ftsE
KD35_27660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KD35_27665	COG0653	protein targeting
KD35_27670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KD35_27675	COG1278	Cold shock
KD35_27680	COG1040	competence protein
KD35_27685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KD35_27690	COG0791	NLP P60 protein
KD35_27690	COG1388	LysM domain
KD35_27695	COG1733	regulation of RNA biosynthetic process
KD35_27705	COG1307	EDD domain protein, DegV family
KD35_27710	COG1739	Uncharacterized protein family UPF0029
KD35_27715	COG1316	TRANSCRIPTIONal
KD35_27720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KD35_27725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KD35_27730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KD35_27740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KD35_27740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KD35_27755	COG3394	polysaccharide catabolic process
KD35_27760	COG1486	melibiose metabolic process
KD35_27765	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_27770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_27780	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KD35_27785	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KD35_27790	COG1447	Phosphotransferase system cellobiose-specific component IIA
KD35_27800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KD35_27805	COG1301	dicarboxylic acid transport
KD35_27815	COG0346	lactoylglutathione lyase activity
KD35_27820	COG1511	domain protein
KD35_27825	COG0583	DNA-binding transcription factor activity
KD35_27830	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KD35_27880	COG3344	reverse transcriptase
KD35_27960	COG3344	reverse transcriptase
KD35_28170	COG4962	Type ii secretion system protein e
KD35_28305	COG2311	Membrane
KD35_28330	COG4196	transglutaminase domain protein
KD35_28335	COG0671	phosphoesterase, PA-phosphatase related
KD35_28360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KD35_28365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KD35_28380	COG2801	Transposase and inactivated derivatives
KD35_28535	COG2002	toxin-antitoxin pair type II binding
KD35_28545	COG4974	Belongs to the 'phage' integrase family
KD35_28585	COG2801	Transposase and inactivated derivatives
KD35_28605	COG3443	Belongs to the bacterial solute-binding protein 9 family
KD35_28615	COG4974	Belongs to the 'phage' integrase family
KD35_28640	COG0457	Tetratricopeptide repeat
KD35_28645	COG1923	regulation of RNA biosynthetic process
KD35_28725	COG0791	NLP P60 protein
KD35_28725	COG0741	lytic transglycosylase activity
KD35_28870	COG1192	Involved in chromosome partitioning
KD35_28890	COG2801	Transposase and inactivated derivatives
KD35_28915	COG1683	Conserved Protein
KD35_28920	COG1309	transcriptional regulator
KD35_28990	COG0681	Belongs to the peptidase S26 family
KD35_29020	COG1280	lysine exporter protein (LysE YggA)
KD35_29055	COG4166	transmembrane transport
KD35_29070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KD35_29130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KD35_29135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone