locus-tag	class	description
KM394_00010	COG0592	DNA-directed DNA polymerase activity
KM394_00015	COG2501	S4 domain
KM394_00025	COG0187	DNA topoisomerase II activity
KM394_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM394_00065	COG0516	GMP reductase activity
KM394_00065	COG0517	IMP dehydrogenase activity
KM394_00070	COG1686	Belongs to the peptidase S11 family
KM394_00100	COG1428	Deoxynucleoside kinase
KM394_00105	COG1428	Deoxynucleoside kinase
KM394_00110	COG1335	isochorismatase
KM394_00115	COG0590	tRNA wobble adenosine to inosine editing
KM394_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM394_00180	COG1982	Orn Lys Arg decarboxylase major
KM394_00190	COG0470	DNA polymerase III
KM394_00195	COG1774	PSP1 C-terminal conserved region
KM394_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM394_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM394_00220	COG2002	toxin-antitoxin pair type II binding
KM394_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM394_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM394_00230	COG0084	hydrolase, TatD family'
KM394_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM394_00250	COG4466	Protein conserved in bacteria
KM394_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM394_00270	COG0251	oxidation-reduction process
KM394_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM394_00305	COG2002	toxin-antitoxin pair type II binding
KM394_00310	COG2244	polysaccharide biosynthetic process
KM394_00315	COG3956	TIGRFAM MazG family protein
KM394_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM394_00340	COG1098	S1 RNA binding domain
KM394_00355	COG2208	phosphoserine phosphatase activity
KM394_00360	COG0037	tRNA processing
KM394_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM394_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM394_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM394_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM394_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM394_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM394_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM394_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM394_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM394_00420	COG1396	sequence-specific DNA binding
KM394_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM394_00455	COG3880	PFAM UvrB UvrC protein
KM394_00465	COG0542	response to heat
KM394_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM394_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM394_00500	COG1045	serine acetyltransferase
KM394_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM394_00520	COG3688	RNA-binding protein containing a PIN domain
KM394_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM394_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM394_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM394_00565	COG2813	Specifically methylates the guanine in position
KM394_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM394_00580	COG1358	cellular component organization or biogenesis
KM394_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM394_00710	COG0201	protein transport
KM394_00720	COG0024	Methionine aminopeptidase
KM394_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM394_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM394_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM394_00795	COG0489	protein tyrosine kinase activity
KM394_00805	COG2194	sulfuric ester hydrolase activity
KM394_00810	COG0726	polysaccharide deacetylase
KM394_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM394_00895	COG4856	YbbR-like protein
KM394_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM394_00915	COG0596	Alpha beta hydrolase
KM394_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM394_00940	COG4946	Tricorn protease homolog
KM394_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM394_00940	COG1506	peptidase
KM394_00975	COG2011	ABC-type metal ion transport system permease component
KM394_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM394_00985	COG1464	Belongs to the NlpA lipoprotein family
KM394_00990	COG0604	alcohol dehydrogenase
KM394_01000	COG0277	FAD linked oxidase domain protein
KM394_01005	COG2271	Major facilitator Superfamily
KM394_01015	COG2814	Major facilitator Superfamily
KM394_01030	COG0601	transmembrane transport
KM394_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM394_01040	COG0444	Belongs to the ABC transporter superfamily
KM394_01045	COG4608	Belongs to the ABC transporter superfamily
KM394_01050	COG4166	transmembrane transport
KM394_01060	COG2207	Transcriptional regulator
KM394_01075	COG4166	transmembrane transport
KM394_01080	COG4166	transmembrane transport
KM394_01085	COG0656	L-ascorbic acid biosynthetic process
KM394_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM394_01105	COG4149	molybdate abc transporter
KM394_01115	COG1910	domain protein
KM394_01125	COG0583	DNA-binding transcription factor activity
KM394_01130	COG0697	spore germination
KM394_01145	COG0204	Acyl-transferase
KM394_01155	COG1609	Transcriptional regulator
KM394_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_01175	COG0084	hydrolase, TatD family'
KM394_01180	COG5298	Protein conserved in bacteria
KM394_01205	COG0488	(ABC) transporter
KM394_01220	COG0747	negative chemotaxis
KM394_01225	COG0601	transmembrane transport
KM394_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM394_01235	COG0444	Belongs to the ABC transporter superfamily
KM394_01240	COG4608	Belongs to the ABC transporter superfamily
KM394_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM394_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM394_01290	COG2814	Major facilitator Superfamily
KM394_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM394_01310	COG4294	response to UV
KM394_01315	COG0457	Tetratricopeptide repeat
KM394_01315	COG0705	Rhomboid family
KM394_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM394_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM394_01335	COG0864	Transcriptional regulator
KM394_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM394_01345	COG2183	response to ionizing radiation
KM394_01440	COG0802	atpase or kinase
KM394_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM394_01450	COG0456	acetyltransferase
KM394_01460	COG0488	(ABC) transporter
KM394_01475	COG1266	CAAX protease self-immunity
KM394_01495	COG2252	PERMEase
KM394_01505	COG5002	protein histidine kinase activity
KM394_01535	COG2226	methyltransferase
KM394_01545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM394_01575	COG1968	undecaprenyl-diphosphatase activity
KM394_01590	COG2205	protein histidine kinase activity
KM394_01595	COG0745	RESPONSE REGULATOR receiver
KM394_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM394_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM394_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM394_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM394_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM394_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM394_01670	COG0151	Belongs to the GarS family
KM394_01695	COG0210	DNA helicase
KM394_01705	COG4851	CamS sex pheromone cAM373 precursor
KM394_01725	COG1335	isochorismatase
KM394_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM394_01735	COG2011	ABC-type metal ion transport system permease component
KM394_01740	COG1464	Belongs to the NlpA lipoprotein family
KM394_01760	COG1846	Transcriptional regulator
KM394_01785	COG1597	lipid kinase activity
KM394_01790	COG0546	phosphoglycolate phosphatase activity
KM394_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM394_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM394_01810	COG2076	Multidrug Resistance protein
KM394_01815	COG2309	aminopeptidase activity
KM394_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM394_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM394_01850	COG4807	Protein conserved in bacteria
KM394_01875	COG1757	Na H antiporter
KM394_01880	COG1473	amidohydrolase
KM394_01895	COG0450	alkyl hydroperoxide reductase
KM394_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_01940	COG0166	Belongs to the GPI family
KM394_01975	COG5002	protein histidine kinase activity
KM394_01995	COG3541	Predicted nucleotidyltransferase
KM394_02000	COG2814	Major facilitator Superfamily
KM394_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM394_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM394_02015	COG0765	amino acid transport
KM394_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM394_02030	COG0840	transmembrane signaling receptor activity
KM394_02035	COG0840	transmembrane signaling receptor activity
KM394_02040	COG0366	Alpha amylase catalytic
KM394_02045	COG2190	(PTS) system
KM394_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_02045	COG1263	PTS System
KM394_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM394_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM394_02100	COG1116	anion transmembrane transporter activity
KM394_02105	COG0488	(ABC) transporter
KM394_02150	COG2270	Major facilitator Superfamily
KM394_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM394_02180	COG2310	stress, protein
KM394_02185	COG2310	stress, protein
KM394_02190	COG2310	stress, protein
KM394_02195	COG0861	Integral membrane protein TerC family
KM394_02205	COG3853	Toxic anion resistance protein (TelA)
KM394_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM394_02230	COG1295	ribonuclease BN
KM394_02235	COG2217	Heavy metal translocating P-type atpase
KM394_02240	COG0697	spore germination
KM394_02260	COG0586	Pfam SNARE associated Golgi protein
KM394_02275	COG3871	stress protein (general stress protein 26)
KM394_02280	COG0387	Pfam Sodium calcium exchanger
KM394_02290	COG0535	radical SAM domain protein
KM394_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM394_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM394_02325	COG0582	viral genome integration into host DNA
KM394_02335	COG1396	sequence-specific DNA binding
KM394_02350	COG1396	sequence-specific DNA binding
KM394_02385	COG1484	DNA-dependent DNA replication
KM394_02615	COG0101	tRNA pseudouridine synthase activity
KM394_02625	COG3829	transcription factor binding
KM394_02635	COG0833	amino acid
KM394_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM394_02670	COG1263	PTS System
KM394_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM394_02690	COG0463	Glycosyl transferase, family 2
KM394_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM394_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM394_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM394_02745	COG1228	amidohydrolase
KM394_02750	COG1090	epimerase
KM394_02780	COG1988	membrane-bound metal-dependent
KM394_02785	COG1194	a g-specific adenine glycosylase
KM394_02810	COG1132	(ABC) transporter
KM394_02815	COG4129	membrane
KM394_02820	COG0070	glutamate synthase
KM394_02820	COG0069	glutamate synthase activity
KM394_02820	COG0067	glutamate synthase
KM394_02830	COG4555	ABC transporter
KM394_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM394_02855	COG0735	belongs to the Fur family
KM394_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM394_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM394_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM394_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM394_03005	COG2766	serine protein kinase
KM394_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM394_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM394_03040	COG2268	Band 7 protein
KM394_03050	COG3290	protein histidine kinase activity
KM394_03055	COG4565	transcriptional regulatory protein
KM394_03060	COG2851	Citrate transporter
KM394_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM394_03085	COG3842	ATPase activity
KM394_03090	COG1175	transmembrane transport
KM394_03095	COG0395	ABC-type sugar transport system, permease component
KM394_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM394_03110	COG0745	RESPONSE REGULATOR receiver
KM394_03115	COG5002	protein histidine kinase activity
KM394_03125	COG4990	cell redox homeostasis
KM394_03135	COG3290	protein histidine kinase activity
KM394_03140	COG4565	transcriptional regulatory protein
KM394_03145	COG3493	citrate carrier protein
KM394_03150	COG0281	malic enzyme
KM394_03160	COG0697	spore germination
KM394_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_03175	COG5002	protein histidine kinase activity
KM394_03180	COG0745	RESPONSE REGULATOR receiver
KM394_03185	COG0454	-acetyltransferase
KM394_03185	COG0456	acetyltransferase
KM394_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM394_03195	COG3383	formate dehydrogenase (NAD+) activity
KM394_03200	COG2427	Protein of unknown function (DUF1641)
KM394_03215	COG0531	amino acid
KM394_03220	COG0640	Transcriptional regulator
KM394_03225	COG2217	Heavy metal translocating P-type atpase
KM394_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM394_03245	COG3227	Zinc metalloprotease (Elastase)
KM394_03265	COG2720	vancomycin resistance protein
KM394_03270	COG1316	TRANSCRIPTIONal
KM394_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_03280	COG0346	lactoylglutathione lyase activity
KM394_03285	COG1253	flavin adenine dinucleotide binding
KM394_03290	COG1027	Aspartate ammonia-lyase
KM394_03295	COG1620	l-lactate permease
KM394_03310	COG3104	oligopeptide transport
KM394_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_03335	COG2226	methyltransferase
KM394_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM394_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM394_03355	COG4548	von Willebrand factor, type A
KM394_03360	COG0714	Associated with various cellular activities
KM394_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM394_03385	COG0531	amino acid
KM394_03390	COG2188	Transcriptional regulator
KM394_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_03395	COG1263	PTS System
KM394_03400	COG0366	Alpha amylase catalytic
KM394_03415	COG0697	spore germination
KM394_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM394_03430	COG1115	amino acid carrier protein
KM394_03435	COG1126	abc transporter atp-binding protein
KM394_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM394_03445	COG0765	amino acid transport
KM394_03450	COG0765	amino acid transport
KM394_03455	COG0833	amino acid
KM394_03480	COG2378	regulation of single-species biofilm formation
KM394_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM394_03490	COG5002	protein histidine kinase activity
KM394_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM394_03520	COG0747	negative chemotaxis
KM394_03530	COG0601	transmembrane transport
KM394_03535	COG4608	Belongs to the ABC transporter superfamily
KM394_03545	COG2271	Major facilitator Superfamily
KM394_03550	COG1846	Transcriptional regulator
KM394_03560	COG1609	Transcriptional regulator
KM394_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM394_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM394_03585	COG1879	ABC-type sugar transport system periplasmic component
KM394_03610	COG1063	alcohol dehydrogenase
KM394_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM394_03650	COG1968	undecaprenyl-diphosphatase activity
KM394_03655	COG0840	transmembrane signaling receptor activity
KM394_03660	COG3584	3D domain protein
KM394_03660	COG1388	LysM domain
KM394_03665	COG1476	TRANSCRIPTIONal
KM394_03680	COG3104	oligopeptide transport
KM394_03685	COG1114	Component of the transport system for branched-chain amino acids
KM394_03700	COG1113	amino acid transport
KM394_03705	COG2252	PERMEase
KM394_03730	COG0475	glutathione-regulated potassium exporter activity
KM394_03730	COG0569	domain protein
KM394_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM394_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM394_03755	COG0833	amino acid
KM394_03760	COG4990	cell redox homeostasis
KM394_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM394_03780	COG0697	spore germination
KM394_03785	COG0531	amino acid
KM394_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM394_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM394_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM394_03805	COG1918	ferrous iron import across plasma membrane
KM394_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM394_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM394_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM394_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM394_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM394_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM394_03975	COG1116	anion transmembrane transporter activity
KM394_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM394_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM394_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM394_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM394_04000	COG2104	thiamine diphosphate biosynthetic process
KM394_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM394_04015	COG0351	phosphomethylpyrimidine kinase
KM394_04055	COG2205	protein histidine kinase activity
KM394_04060	COG2814	Major facilitator Superfamily
KM394_04065	COG1846	Transcriptional regulator
KM394_04080	COG2252	PERMEase
KM394_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM394_04105	COG1621	beta-fructofuranosidase activity
KM394_04110	COG1263	PTS System
KM394_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_04115	COG1609	Transcriptional regulator
KM394_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM394_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM394_04165	COG0778	Nitroreductase
KM394_04170	COG2719	SpoVR family
KM394_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM394_04200	COG1937	Protein conserved in bacteria
KM394_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM394_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM394_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM394_04235	COG0730	response to heat
KM394_04245	COG1316	TRANSCRIPTIONal
KM394_04250	COG0604	alcohol dehydrogenase
KM394_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM394_04270	COG3711	transcriptional antiterminator
KM394_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM394_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM394_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM394_04300	COG3584	3D domain protein
KM394_04300	COG1388	LysM domain
KM394_04305	COG0577	efflux transmembrane transporter activity
KM394_04310	COG1136	(ABC) transporter
KM394_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM394_04335	COG1114	Component of the transport system for branched-chain amino acids
KM394_04340	COG3546	catalase activity
KM394_04375	COG0586	Pfam SNARE associated Golgi protein
KM394_04410	COG0531	amino acid
KM394_04415	COG0475	glutathione-regulated potassium exporter activity
KM394_04425	COG1737	Transcriptional regulator
KM394_04435	COG1263	PTS System
KM394_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_04445	COG2259	Doxx family
KM394_04460	COG0697	spore germination
KM394_04465	COG1522	sequence-specific DNA binding
KM394_04480	COG2076	Multidrug Resistance protein
KM394_04485	COG1309	transcriptional regulator
KM394_04490	COG2814	Major facilitator Superfamily
KM394_04495	COG1733	regulation of RNA biosynthetic process
KM394_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM394_04510	COG4533	DNA binding
KM394_04515	COG2211	Major facilitator Superfamily
KM394_04525	COG0693	protein deglycase activity
KM394_04530	COG0693	protein deglycase activity
KM394_04530	COG0753	catalase activity
KM394_04540	COG0531	amino acid
KM394_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM394_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM394_04560	COG1132	(ABC) transporter
KM394_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM394_04575	COG0765	amino acid transport
KM394_04580	COG1126	abc transporter atp-binding protein
KM394_04595	COG0189	ligase activity
KM394_04625	COG0028	Belongs to the TPP enzyme family
KM394_04630	COG3527	Alpha-acetolactate decarboxylase
KM394_04645	COG0561	phosphatase activity
KM394_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM394_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM394_04695	COG0653	protein targeting
KM394_04700	COG2244	polysaccharide biosynthetic process
KM394_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM394_04715	COG4196	transglutaminase domain protein
KM394_04730	COG1696	Membrane protein involved in D-alanine export
KM394_04745	COG1024	Enoyl-CoA hydratase
KM394_04765	COG1363	Peptidase, m42
KM394_04785	COG3938	Belongs to the proline racemase family
KM394_04825	COG0601	transmembrane transport
KM394_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM394_04840	COG4608	Belongs to the ABC transporter superfamily
KM394_04845	COG0322	excinuclease ABC activity
KM394_04875	COG0477	Major facilitator Superfamily
KM394_04880	COG3290	protein histidine kinase activity
KM394_04885	COG4565	transcriptional regulatory protein
KM394_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM394_04920	COG0789	Transcriptional regulator
KM394_04920	COG4978	Transcriptional regulator
KM394_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM394_04975	COG0477	Major facilitator Superfamily
KM394_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM394_05020	COG3320	Male sterility
KM394_05025	COG1309	transcriptional regulator
KM394_05045	COG1183	phosphatidylcholine synthase activity
KM394_05065	COG2376	Dihydroxyacetone kinase
KM394_05075	COG2376	Dihydroxyacetone kinase
KM394_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM394_05085	COG1959	2 iron, 2 sulfur cluster binding
KM394_05115	COG2770	Histidine kinase
KM394_05115	COG3437	response regulator, receiver
KM394_05165	COG3237	CsbD-like
KM394_05190	COG1191	sigma factor activity
KM394_05200	COG2208	phosphoserine phosphatase activity
KM394_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM394_05210	COG0784	Response regulator, receiver
KM394_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM394_05210	COG2198	Histidine kinase
KM394_05210	COG2205	protein histidine kinase activity
KM394_05265	COG0420	3'-5' exonuclease activity
KM394_05270	COG4717	serine-type aminopeptidase activity
KM394_05290	COG1309	transcriptional regulator
KM394_05295	COG2814	Major facilitator Superfamily
KM394_05300	COG0346	lactoylglutathione lyase activity
KM394_05305	COG0346	lactoylglutathione lyase activity
KM394_05310	COG0457	Tetratricopeptide repeat
KM394_05315	COG2267	carboxylic ester hydrolase activity
KM394_05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM394_05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM394_05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM394_05390	COG0477	Major facilitator Superfamily
KM394_05395	COG0477	Major facilitator Superfamily
KM394_05405	COG3973	AAA domain
KM394_05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM394_05430	COG4980	gas vesicle protein
KM394_05435	COG0537	adenosine 5'-monophosphoramidase activity
KM394_05440	COG1131	(ABC) transporter
KM394_05445	COG4473	ABC transporter
KM394_05460	COG1309	transcriptional regulator
KM394_05470	COG3402	PFAM membrane-flanked domain
KM394_05520	COG3402	PFAM membrane-flanked domain
KM394_05525	COG3428	Bacterial PH domain
KM394_05530	COG2329	Antibiotic biosynthesis monooxygenase
KM394_05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM394_05545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM394_05550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM394_05585	COG1309	transcriptional regulator
KM394_05590	COG1511	domain protein
KM394_05615	COG1609	Transcriptional regulator
KM394_05625	COG1234	tRNA 3'-trailer cleavage
KM394_05630	COG0095	Lipoate-protein ligase
KM394_05640	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_05670	COG3209	COG3209 Rhs family protein
KM394_05710	COG1078	dGTPase activity
KM394_05720	COG1595	DNA-templated transcription, initiation
KM394_05725	COG3708	Transcriptional regulator
KM394_05725	COG2207	Transcriptional regulator
KM394_05745	COG0745	RESPONSE REGULATOR receiver
KM394_05770	COG0501	Belongs to the peptidase M48B family
KM394_05780	COG0697	spore germination
KM394_05800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM394_05805	COG2224	Isocitrate lyase
KM394_05830	COG4903	ComK protein
KM394_05835	COG0398	Pfam SNARE associated Golgi protein
KM394_05845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM394_05850	COG1074	ATP-dependent DNA helicase activity
KM394_05895	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM394_05920	COG0367	asparagine synthase
KM394_05925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM394_05930	COG0753	catalase activity
KM394_05935	COG0004	ammonium transporteR
KM394_05955	COG2996	Protein conserved in bacteria
KM394_05965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM394_05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_05990	COG0561	phosphatase activity
KM394_06000	COG0542	response to heat
KM394_06010	COG2267	carboxylic ester hydrolase activity
KM394_06025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_06030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM394_06035	COG5504	Zn-dependent protease
KM394_06045	COG0180	Tryptophanyl-tRNA synthetase
KM394_06055	COG4166	transmembrane transport
KM394_06060	COG0601	transmembrane transport
KM394_06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM394_06070	COG0444	Belongs to the ABC transporter superfamily
KM394_06075	COG4608	Belongs to the ABC transporter superfamily
KM394_06080	COG0534	Mate efflux family protein
KM394_06085	COG4166	transmembrane transport
KM394_06100	COG0861	Integral membrane protein TerC family
KM394_06105	COG4862	establishment of competence for transformation
KM394_06110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM394_06120	COG1164	Oligoendopeptidase f
KM394_06130	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM394_06135	COG2346	COG2346, Truncated hemoglobins
KM394_06140	COG4116	CYTH
KM394_06150	COG2357	RelA SpoT domain protein
KM394_06160	COG0564	pseudouridine synthase activity
KM394_06180	COG1216	Glycosyl transferase, family 2
KM394_06180	COG0463	Glycosyl transferase, family 2
KM394_06200	COG0457	Tetratricopeptide repeat
KM394_06200	COG0463	Glycosyl transferase, family 2
KM394_06220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM394_06235	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM394_06280	COG2153	protein acetylation
KM394_06290	COG2382	esterase
KM394_06305	COG5492	domain, Protein
KM394_06310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM394_06320	COG0512	Glutamine amidotransferase of anthranilate synthase
KM394_06320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM394_06355	COG1620	l-lactate permease
KM394_06360	COG5634	Uncharacterized conserved protein (DUF2278)
KM394_06415	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM394_06425	COG1476	TRANSCRIPTIONal
KM394_06485	COG2226	methyltransferase
KM394_06495	COG1686	Belongs to the peptidase S11 family
KM394_06500	COG0681	Belongs to the peptidase S26 family
KM394_06535	COG1012	belongs to the aldehyde dehydrogenase family
KM394_06540	COG3842	ATPase activity
KM394_06545	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM394_06550	COG1177	transmembrane transport
KM394_06555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM394_06565	COG2409	Drug exporters of the RND superfamily
KM394_06575	COG0564	pseudouridine synthase activity
KM394_06585	COG2340	Cysteine-rich secretory protein family
KM394_06590	COG0247	lactate metabolic process
KM394_06595	COG0277	FAD linked oxidase domain protein
KM394_06600	COG3835	regulator
KM394_06610	COG0745	RESPONSE REGULATOR receiver
KM394_06615	COG5002	protein histidine kinase activity
KM394_06620	COG2186	Transcriptional regulator
KM394_06640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM394_06655	COG2116	formate transmembrane transporter activity
KM394_06660	COG0861	Integral membrane protein TerC family
KM394_06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM394_06675	COG2030	dehydratase
KM394_06695	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_06700	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM394_06705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM394_06710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM394_06725	COG1840	ABC-type Fe3 transport system, periplasmic component
KM394_06755	COG1349	DNA-binding transcription factor activity
KM394_06775	COG2861	carbohydrate metabolic process
KM394_06785	COG3852	Histidine kinase
KM394_06790	COG1846	Transcriptional regulator
KM394_06800	COG2318	DinB family
KM394_06805	COG5002	protein histidine kinase activity
KM394_06815	COG0720	synthase
KM394_06830	COG4873	Protein conserved in bacteria
KM394_06860	COG1780	Probably involved in ribonucleotide reductase function
KM394_06880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM394_06885	COG1725	Transcriptional regulator
KM394_06890	COG1131	(ABC) transporter
KM394_06900	COG1131	(ABC) transporter
KM394_06905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM394_06920	COG1522	sequence-specific DNA binding
KM394_06930	COG1335	isochorismatase
KM394_06940	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM394_06945	COG2070	2-Nitropropane dioxygenase
KM394_06950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM394_06960	COG1696	Membrane protein involved in D-alanine export
KM394_06980	COG0716	FMN binding
KM394_06995	COG3173	Aminoglycoside phosphotransferase
KM394_07015	COG0534	Mate efflux family protein
KM394_07020	COG1968	undecaprenyl-diphosphatase activity
KM394_07035	COG1846	Transcriptional regulator
KM394_07045	COG1301	dicarboxylic acid transport
KM394_07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM394_07055	COG4709	membrane
KM394_07060	COG3874	Sporulation protein YtfJ
KM394_07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM394_07090	COG0028	Belongs to the TPP enzyme family
KM394_07095	COG0440	acetolactate synthase activity
KM394_07100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM394_07110	COG0473	3-isopropylmalate dehydrogenase activity
KM394_07135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM394_07170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM394_07185	COG1183	phosphatidylcholine synthase activity
KM394_07190	COG1368	sulfuric ester hydrolase activity
KM394_07200	COG0019	diaminopimelate decarboxylase activity
KM394_07220	COG0529	Catalyzes the synthesis of activated sulfate
KM394_07225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM394_07245	COG1648	precorrin-2 dehydrogenase activity
KM394_07250	COG0733	neurotransmitter:sodium symporter activity
KM394_07270	COG1757	Na H antiporter
KM394_07285	COG4758	membrane
KM394_07290	COG4585	Histidine kinase
KM394_07295	COG2197	response regulator
KM394_07305	COG1114	Component of the transport system for branched-chain amino acids
KM394_07315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM394_07340	COG1017	nitric oxide dioxygenase activity
KM394_07340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM394_07355	COG0730	response to heat
KM394_07360	COG0306	phosphate transporter
KM394_07365	COG1392	Phosphate transport regulator
KM394_07370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM394_07385	COG3852	Histidine kinase
KM394_07390	COG1801	Protein of unknown function DUF72
KM394_07400	COG0582	viral genome integration into host DNA
KM394_07405	COG5002	protein histidine kinase activity
KM394_07425	COG0392	lysyltransferase activity
KM394_07425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM394_07440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM394_07445	COG1686	Belongs to the peptidase S11 family
KM394_07450	COG2715	membrane protein required for spore maturation
KM394_07455	COG0700	Nucleoside recognition
KM394_07460	COG1187	pseudouridine synthase activity
KM394_07470	COG1333	cytochrome c biogenesis protein
KM394_07475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM394_07480	COG0745	RESPONSE REGULATOR receiver
KM394_07485	COG5002	protein histidine kinase activity
KM394_07490	COG2096	Adenosyltransferase
KM394_07505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM394_07510	COG1141	Ferredoxin
KM394_07515	COG4955	Helix-turn-helix domain
KM394_07520	COG0514	ATP-dependent DNA helicase (RecQ)
KM394_07525	COG1266	CAAX protease self-immunity
KM394_07545	COG4862	establishment of competence for transformation
KM394_07550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM394_07570	COG0492	ferredoxin-NADP+ reductase activity
KM394_07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM394_07660	COG0142	geranyltranstransferase activity
KM394_07670	COG0142	geranyltranstransferase activity
KM394_07690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM394_07695	COG0457	Tetratricopeptide repeat
KM394_07715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM394_07725	COG4347	Protein of unknown function (DUF1405)
KM394_07740	COG2738	Putative neutral zinc metallopeptidase
KM394_07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_07755	COG1694	Mazg nucleotide pyrophosphohydrolase
KM394_07770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM394_07775	COG0438	transferase activity, transferring glycosyl groups
KM394_07810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM394_07810	COG1199	ATP-dependent helicase activity
KM394_07830	COG3935	DnaD domain protein
KM394_07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM394_07845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM394_07845	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM394_07905	COG0116	Belongs to the methyltransferase superfamily
KM394_07915	COG1199	ATP-dependent helicase activity
KM394_07920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM394_07930	COG3173	Aminoglycoside phosphotransferase
KM394_07935	COG0024	Methionine aminopeptidase
KM394_07945	COG2233	PERMEase
KM394_07950	COG2311	Membrane
KM394_07955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM394_07965	COG0456	acetyltransferase
KM394_08015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM394_08040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM394_08055	COG1215	transferase activity, transferring glycosyl groups
KM394_08075	COG0454	-acetyltransferase
KM394_08095	COG0328	RNA-DNA hybrid ribonuclease activity
KM394_08135	COG1280	lysine exporter protein (LysE YggA)
KM394_08150	COG3162	membrane
KM394_08155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM394_08160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM394_08170	COG0475	glutathione-regulated potassium exporter activity
KM394_08175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM394_08180	COG0789	Transcriptional regulator
KM394_08180	COG4978	Transcriptional regulator
KM394_08190	COG2323	membrane
KM394_08195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM394_08250	COG1923	regulation of RNA biosynthetic process
KM394_08260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM394_08265	COG1360	Flagellar Motor Protein
KM394_08270	COG2201	protein-glutamate methylesterase activity
KM394_08275	COG2198	Histidine kinase
KM394_08275	COG0643	Histidine kinase
KM394_08280	COG2198	Histidine kinase
KM394_08280	COG0643	Histidine kinase
KM394_08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM394_08285	COG1776	CheC inhibitor of MCP methylation
KM394_08300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM394_08320	COG1256	bacterial-type flagellum assembly
KM394_08345	COG1815	bacterial-type flagellum-dependent cell motility
KM394_08350	COG1558	bacterial-type flagellum-dependent cell motility
KM394_08365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM394_08375	COG1157	protein secretion by the type III secretion system
KM394_08415	COG0784	Response regulator, receiver
KM394_08415	COG0835	chemotaxis
KM394_08425	COG0463	Glycosyl transferase, family 2
KM394_08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM394_08470	COG0741	lytic transglycosylase activity
KM394_08485	COG1776	CheC inhibitor of MCP methylation
KM394_08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM394_08495	COG1338	Plays a role in the flagellum-specific transport system
KM394_08500	COG1987	bacterial-type flagellum assembly
KM394_08510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM394_08515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM394_08520	COG1419	protein localization to endoplasmic reticulum
KM394_08525	COG4786	Flagellar basal body rod
KM394_08530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM394_08555	COG1309	transcriptional regulator
KM394_08575	COG2329	Antibiotic biosynthesis monooxygenase
KM394_08600	COG0583	DNA-binding transcription factor activity
KM394_08605	COG3842	ATPase activity
KM394_08610	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM394_08620	COG1234	tRNA 3'-trailer cleavage
KM394_08645	COG1686	Belongs to the peptidase S11 family
KM394_08655	COG0406	alpha-ribazole phosphatase activity
KM394_08685	COG0367	asparagine synthase
KM394_08715	COG1802	Transcriptional regulator
KM394_08720	COG0697	spore germination
KM394_08725	COG0523	cobalamin synthesis protein
KM394_08730	COG0701	Predicted permease
KM394_08740	COG1216	Glycosyl transferase, family 2
KM394_08740	COG0438	transferase activity, transferring glycosyl groups
KM394_08745	COG1757	Na H antiporter
KM394_08750	COG0114	fumarate hydratase activity
KM394_08775	COG3340	Belongs to the peptidase S51 family
KM394_08795	COG0785	Cytochrome C biogenesis protein
KM394_08825	COG2733	membrane
KM394_08865	COG1131	(ABC) transporter
KM394_08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM394_08885	COG0528	UMP kinase activity
KM394_08895	COG1027	Aspartate ammonia-lyase
KM394_08900	COG0281	malic enzyme
KM394_08905	COG4191	Histidine kinase
KM394_08910	COG0784	Response regulator, receiver
KM394_08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM394_08970	COG1051	belongs to the nudix hydrolase family
KM394_08975	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM394_08985	COG2814	Major facilitator Superfamily
KM394_09000	COG1966	Carbon starvation protein
KM394_09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM394_09035	COG2223	nitrite transmembrane transporter activity
KM394_09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM394_09055	COG2244	polysaccharide biosynthetic process
KM394_09060	COG0733	neurotransmitter:sodium symporter activity
KM394_09070	COG5566	PFAM Mor transcription activator
KM394_09075	COG2323	membrane
KM394_09090	COG2084	Dehydrogenase
KM394_09105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM394_09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM394_09120	COG0028	Belongs to the TPP enzyme family
KM394_09125	COG0440	acetolactate synthase activity
KM394_09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM394_09140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM394_09165	COG2814	Major facilitator Superfamily
KM394_09170	COG3384	dioxygenase
KM394_09180	COG3279	Response regulator of the LytR AlgR family
KM394_09185	COG0427	acetyl-CoA hydrolase
KM394_09205	COG1073	alpha beta
KM394_09235	COG0535	radical SAM domain protein
KM394_09260	COG1914	H( )-stimulated, divalent metal cation uptake system
KM394_09305	COG2390	Transcriptional regulator
KM394_09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM394_09335	COG4224	UPF0291 protein
KM394_09355	COG0006	proline dipeptidase activity
KM394_09360	COG2132	Multicopper oxidase
KM394_09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM394_09390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM394_09405	COG1276	copper resistance
KM394_09405	COG2372	response to copper ion
KM394_09410	COG4549	nuclear export factor GLE1
KM394_09420	COG0697	spore germination
KM394_09425	COG0583	DNA-binding transcription factor activity
KM394_09430	COG1959	2 iron, 2 sulfur cluster binding
KM394_09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM394_09440	COG0778	Nitroreductase
KM394_09450	COG0628	permease
KM394_09460	COG1231	oxidoreductase activity
KM394_09465	COG0523	cobalamin synthesis protein
KM394_09480	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_09485	COG2030	dehydratase
KM394_09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_09500	COG0411	ABC transporter
KM394_09520	COG0583	DNA-binding transcription factor activity
KM394_09530	COG1942	4-Oxalocrotonate Tautomerase
KM394_09540	COG1846	Transcriptional regulator
KM394_09550	COG1271	oxidase subunit
KM394_09555	COG1294	oxidase, subunit
KM394_09560	COG4988	ABC transporter
KM394_09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM394_09585	COG1686	Belongs to the peptidase S11 family
KM394_09600	COG0791	NLP P60 protein
KM394_09600	COG1388	LysM domain
KM394_09615	COG0745	RESPONSE REGULATOR receiver
KM394_09620	COG5002	protein histidine kinase activity
KM394_09630	COG0300	oxidoreductase activity
KM394_09665	COG0460	homoserine dehydrogenase
KM394_09690	COG1316	TRANSCRIPTIONal
KM394_09700	COG0745	RESPONSE REGULATOR receiver
KM394_09705	COG5002	protein histidine kinase activity
KM394_09720	COG1285	pathogenesis
KM394_09725	COG1247	-acetyltransferase
KM394_09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM394_09755	COG1082	Xylose isomerase domain protein TIM barrel
KM394_09770	COG1279	arginine transmembrane transporter activity
KM394_09780	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM394_09820	COG2002	toxin-antitoxin pair type II binding
KM394_09825	COG1404	Belongs to the peptidase S8 family
KM394_09830	COG0640	Transcriptional regulator
KM394_09835	COG0667	Aldo Keto reductase
KM394_09840	COG2814	Major facilitator Superfamily
KM394_09865	COG0840	transmembrane signaling receptor activity
KM394_09880	COG3949	Membrane
KM394_09885	COG0783	Belongs to the Dps family
KM394_09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM394_09910	COG1231	oxidoreductase activity
KM394_09920	COG4989	oxidoreductase activity
KM394_09925	COG0523	cobalamin synthesis protein
KM394_09930	COG0456	acetyltransferase
KM394_09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM394_09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM394_09995	COG0702	epimerase
KM394_10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM394_10015	COG4166	transmembrane transport
KM394_10030	COG0406	alpha-ribazole phosphatase activity
KM394_10040	COG5337	Spore coat protein CotH
KM394_10045	COG1051	belongs to the nudix hydrolase family
KM394_10050	COG0586	Pfam SNARE associated Golgi protein
KM394_10055	COG2244	polysaccharide biosynthetic process
KM394_10065	COG0701	Predicted permease
KM394_10070	COG3689	TIGRFAM TIGR03943 family protein
KM394_10075	COG1607	acyl-coa hydrolase
KM394_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM394_10100	COG0702	epimerase
KM394_10105	COG2839	Protein conserved in bacteria
KM394_10110	COG1253	flavin adenine dinucleotide binding
KM394_10125	COG1114	Component of the transport system for branched-chain amino acids
KM394_10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM394_10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM394_10160	COG1876	peptidase activity
KM394_10170	COG0154	amidase activity
KM394_10175	COG2211	Major facilitator Superfamily
KM394_10195	COG0561	phosphatase activity
KM394_10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM394_10210	COG4106	trans-aconitate 2-methyltransferase activity
KM394_10225	COG1819	glycosyl
KM394_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_10260	COG0456	acetyltransferase
KM394_10310	COG3874	Sporulation protein YtfJ
KM394_10335	COG2226	methyltransferase
KM394_10360	COG0346	lactoylglutathione lyase activity
KM394_10370	COG0604	alcohol dehydrogenase
KM394_10375	COG1595	DNA-templated transcription, initiation
KM394_10400	COG0386	Belongs to the glutathione peroxidase family
KM394_10405	COG1305	Transglutaminase-like
KM394_10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM394_10415	COG0714	Associated with various cellular activities
KM394_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM394_10435	COG1140	nitrate reductase beta subunit
KM394_10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM394_10445	COG2181	nitrate reductase activity
KM394_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM394_10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM394_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM394_10480	COG0303	'Molybdopterin
KM394_10485	COG0314	molybdopterin synthase activity
KM394_10495	COG2223	nitrite transmembrane transporter activity
KM394_10510	COG1648	precorrin-2 dehydrogenase activity
KM394_10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM394_10520	COG1587	Uroporphyrinogen-III synthase
KM394_10525	COG2146	nitrite reductase [NAD(P)H] activity
KM394_10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM394_10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM394_10570	COG2359	stage V sporulation protein S
KM394_10585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM394_10600	COG1418	mRNA catabolic process
KM394_10605	COG0488	(ABC) transporter
KM394_10620	COG0629	single-stranded DNA binding
KM394_10635	COG1413	lyase activity
KM394_10650	COG2521	methyltransferase
KM394_10650	COG2136	Putative SAM-dependent methyltransferase
KM394_10655	COG0018	arginyl-trna synthetase
KM394_10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM394_10700	COG0017	Asparaginyl-tRNA synthetase
KM394_10720	COG1674	ftsk spoiiie
KM394_10800	COG1929	Belongs to the glycerate kinase type-1 family
KM394_10805	COG0471	metal ion transport
KM394_10810	COG0745	RESPONSE REGULATOR receiver
KM394_10815	COG3850	Histidine kinase
KM394_10815	COG5002	protein histidine kinase activity
KM394_10830	COG0733	neurotransmitter:sodium symporter activity
KM394_10855	COG2610	gluconate transmembrane transporter activity
KM394_10860	COG1454	alcohol dehydrogenase
KM394_10865	COG1794	racemase activity, acting on amino acids and derivatives
KM394_10875	COG0456	acetyltransferase
KM394_10890	COG1131	(ABC) transporter
KM394_10905	COG0546	phosphoglycolate phosphatase activity
KM394_10925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM394_10940	COG0768	penicillin binding
KM394_10945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM394_10950	COG0204	Acyl-transferase
KM394_10955	COG1272	protein, Hemolysin III
KM394_10965	COG0805	protein transport
KM394_10975	COG1307	EDD domain protein, DegV family
KM394_10980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM394_10985	COG1999	signal sequence binding
KM394_10990	COG0071	Belongs to the small heat shock protein (HSP20) family
KM394_10995	COG0367	asparagine synthase
KM394_11010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM394_11040	COG1051	belongs to the nudix hydrolase family
KM394_11050	COG0668	transmembrane transport
KM394_11055	COG4585	Histidine kinase
KM394_11055	COG2203	Gaf domain
KM394_11060	COG2197	response regulator
KM394_11070	COG1064	alcohol dehydrogenase
KM394_11095	COG1070	Carbohydrate kinase
KM394_11100	COG1070	Carbohydrate kinase
KM394_11130	COG1125	glycine betaine transport
KM394_11130	COG0517	IMP dehydrogenase activity
KM394_11135	COG1174	glycine betaine transport
KM394_11170	COG1253	flavin adenine dinucleotide binding
KM394_11175	COG1012	belongs to the aldehyde dehydrogenase family
KM394_11180	COG5506	Protein of unknown function (DUF1694)
KM394_11195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM394_11200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM394_11205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM394_11210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM394_11215	COG0456	acetyltransferase
KM394_11220	COG3829	transcription factor binding
KM394_11225	COG1509	lysine 2,3-aminomutase activity
KM394_11265	COG4326	sporulation control protein
KM394_11270	COG0671	phosphoesterase, PA-phosphatase related
KM394_11275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM394_11310	COG1787	Restriction endonuclease
KM394_11310	COG1715	Restriction endonuclease
KM394_11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM394_11440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM394_11440	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM394_11445	COG2814	Major facilitator Superfamily
KM394_11450	COG4841	protein insertion into membrane
KM394_11455	COG0372	Belongs to the citrate synthase family
KM394_11460	COG2079	MmgE PrpD family protein
KM394_11465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM394_11470	COG1960	acyl-CoA dehydrogenase activity
KM394_11475	COG2084	Dehydrogenase
KM394_11485	COG1280	lysine exporter protein (LysE YggA)
KM394_11490	COG1024	Enoyl-CoA hydratase
KM394_11505	COG0420	3'-5' exonuclease activity
KM394_11510	COG0419	ATPase involved in DNA repair
KM394_11535	COG2223	nitrite transmembrane transporter activity
KM394_11540	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_11545	COG1169	isochorismate synthase
KM394_11550	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM394_11555	COG1535	isochorismatase
KM394_11555	COG3433	isochorismatase activity
KM394_11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM394_11565	COG3251	PFAM MbtH domain protein
KM394_11570	COG2814	Major facilitator Superfamily
KM394_11585	COG0776	regulation of translation
KM394_11595	COG2318	DinB family
KM394_11605	COG1115	amino acid carrier protein
KM394_11620	COG2329	Antibiotic biosynthesis monooxygenase
KM394_11625	COG1187	pseudouridine synthase activity
KM394_11630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM394_11645	COG0596	Alpha beta hydrolase
KM394_11650	COG2814	Major facilitator Superfamily
KM394_11670	COG2226	methyltransferase
KM394_11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_11750	COG1247	-acetyltransferase
KM394_11780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM394_11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_11800	COG1278	Cold shock
KM394_11815	COG0010	Belongs to the arginase family
KM394_11820	COG0561	phosphatase activity
KM394_11865	COG0583	DNA-binding transcription factor activity
KM394_11870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM394_11885	COG0583	DNA-binding transcription factor activity
KM394_11890	COG2258	MOSC domain
KM394_11905	COG1132	(ABC) transporter
KM394_11910	COG1132	(ABC) transporter
KM394_11930	COG1396	sequence-specific DNA binding
KM394_11955	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM394_11960	COG1595	DNA-templated transcription, initiation
KM394_11985	COG1649	PFAM Uncharacterised BCR, COG1649
KM394_12010	COG2971	BadF BadG BcrA BcrD
KM394_12015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM394_12020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM394_12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_12070	COG1309	transcriptional regulator
KM394_12085	COG1136	(ABC) transporter
KM394_12085	COG0577	efflux transmembrane transporter activity
KM394_12090	COG0500	methyltransferase
KM394_12090	COG3615	Tellurite resistance protein tehB
KM394_12100	COG2226	methyltransferase
KM394_12105	COG3961	Belongs to the TPP enzyme family
KM394_12110	COG1846	Transcriptional regulator
KM394_12150	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM394_12165	COG1595	DNA-templated transcription, initiation
KM394_12175	COG0768	penicillin binding
KM394_12185	COG2367	Beta-lactamase
KM394_12190	COG0671	phosphoesterase, PA-phosphatase related
KM394_12195	COG1609	Transcriptional regulator
KM394_12200	COG2814	Major facilitator Superfamily
KM394_12205	COG0673	inositol 2-dehydrogenase activity
KM394_12215	COG1012	belongs to the aldehyde dehydrogenase family
KM394_12230	COG0191	fructose-bisphosphate aldolase activity
KM394_12235	COG3718	enzyme involved in inositol metabolism
KM394_12260	COG0457	Tetratricopeptide repeat
KM394_12265	COG1476	TRANSCRIPTIONal
KM394_12280	COG1876	peptidase activity
KM394_12300	COG1309	transcriptional regulator
KM394_12305	COG0488	(ABC) transporter
KM394_12320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_12335	COG1252	NADH dehydrogenase
KM394_12340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_12355	COG1131	(ABC) transporter
KM394_12365	COG1309	transcriptional regulator
KM394_12380	COG1960	acyl-CoA dehydrogenase activity
KM394_12385	COG0439	Biotin carboxylase
KM394_12390	COG0511	ligase activity, forming carbon-carbon bonds
KM394_12395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM394_12400	COG1024	Enoyl-CoA hydratase
KM394_12405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM394_12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM394_12420	COG1247	-acetyltransferase
KM394_12425	COG0572	uridine kinase
KM394_12435	COG2318	DinB family
KM394_12440	COG1686	Belongs to the peptidase S11 family
KM394_12465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM394_12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM394_12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM394_12530	COG2814	Major facilitator Superfamily
KM394_12550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM394_12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_12585	COG1063	alcohol dehydrogenase
KM394_12615	COG3773	Cell wall hydrolase
KM394_12625	COG0745	RESPONSE REGULATOR receiver
KM394_12640	COG0488	(ABC) transporter
KM394_12655	COG1136	(ABC) transporter
KM394_12680	COG0460	homoserine dehydrogenase
KM394_12685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_12695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM394_12760	COG2124	cytochrome p450
KM394_12795	COG0561	phosphatase activity
KM394_12805	COG5002	protein histidine kinase activity
KM394_12810	COG0768	penicillin binding
KM394_12815	COG1819	glycosyl
KM394_12820	COG1794	racemase activity, acting on amino acids and derivatives
KM394_12830	COG1122	ATPase activity
KM394_12845	COG2205	protein histidine kinase activity
KM394_12855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM394_12860	COG0604	alcohol dehydrogenase
KM394_12865	COG0768	penicillin binding
KM394_12875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM394_12910	COG0693	protein deglycase activity
KM394_12940	COG2814	Major facilitator Superfamily
KM394_12955	COG0584	glycerophosphoryl diester phosphodiesterase
KM394_12975	COG0697	spore germination
KM394_13000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM394_13010	COG2223	nitrite transmembrane transporter activity
KM394_13025	COG2816	NAD+ diphosphatase activity
KM394_13030	COG0592	DNA-directed DNA polymerase activity
KM394_13035	COG1051	belongs to the nudix hydrolase family
KM394_13070	COG3878	Protein conserved in bacteria
KM394_13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM394_13130	COG0322	excinuclease ABC activity
KM394_13170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM394_13195	COG1011	Hydrolase
KM394_13215	COG0076	glutamate decarboxylase activity
KM394_13230	COG1523	belongs to the glycosyl hydrolase 13 family
KM394_13235	COG3227	Zinc metalloprotease (Elastase)
KM394_13255	COG0201	protein transport
KM394_13265	COG0697	spore germination
KM394_13270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_13300	COG4129	membrane
KM394_13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_13320	COG2959	enzyme of heme biosynthesis
KM394_13340	COG3483	tryptophan 2,3-dioxygenase activity
KM394_13345	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM394_13350	COG3844	kynureninase activity
KM394_13355	COG1309	transcriptional regulator
KM394_13385	COG3284	Transcriptional regulator
KM394_13405	COG1349	DNA-binding transcription factor activity
KM394_13425	COG1959	2 iron, 2 sulfur cluster binding
KM394_13440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM394_13445	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM394_13450	COG0022	dehydrogenase e1 component
KM394_13455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM394_13465	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_13470	COG0456	acetyltransferase
KM394_13470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM394_13500	COG4176	ABC-type proline glycine betaine transport system permease component
KM394_13505	COG0517	IMP dehydrogenase activity
KM394_13505	COG4175	Glycine betaine
KM394_13530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM394_13535	COG2153	protein acetylation
KM394_13540	COG3397	chitin binding
KM394_13555	COG2205	protein histidine kinase activity
KM394_13580	COG0658	competence protein
KM394_13580	COG2333	competence protein COMEC
KM394_13630	COG3973	AAA domain
KM394_13645	COG2105	PFAM AIG2 family protein
KM394_13650	COG0514	ATP-dependent DNA helicase (RecQ)
KM394_13670	COG4637	Psort location Cytoplasmic, score
KM394_13695	COG3397	chitin binding
KM394_13710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM394_13715	COG1115	amino acid carrier protein
KM394_13720	COG1012	belongs to the aldehyde dehydrogenase family
KM394_13725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM394_13735	COG3938	Belongs to the proline racemase family
KM394_13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM394_13780	COG0586	Pfam SNARE associated Golgi protein
KM394_13795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM394_13800	COG0519	Catalyzes the synthesis of GMP from XMP
KM394_13805	COG4166	transmembrane transport
KM394_13815	COG4948	Mandelate Racemase Muconate Lactonizing
KM394_13860	COG2936	dipeptidyl-peptidase activity
KM394_13865	COG5002	protein histidine kinase activity
KM394_13905	COG1164	Oligoendopeptidase f
KM394_13920	COG1307	EDD domain protein, DegV family
KM394_13940	COG2814	Major facilitator Superfamily
KM394_13950	COG1664	Polymer-forming cytoskeletal
KM394_13955	COG0789	Transcriptional regulator
KM394_13960	COG4533	DNA binding
KM394_13965	COG0477	Major facilitator Superfamily
KM394_13965	COG2814	Major facilitator Superfamily
KM394_13985	COG2261	transglycosylase associated protein
KM394_14000	COG2226	methyltransferase
KM394_14035	COG0436	Aminotransferase
KM394_14040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM394_14045	COG5146	pantothenate kinase activity
KM394_14065	COG1131	(ABC) transporter
KM394_14110	COG0628	permease
KM394_14120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM394_14125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM394_14130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM394_14135	COG1116	anion transmembrane transporter activity
KM394_14155	COG2816	NAD+ diphosphatase activity
KM394_14175	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM394_14200	COG0697	spore germination
KM394_14205	COG2318	DinB family
KM394_14225	COG4912	Dna alkylation repair
KM394_14245	COG0861	Integral membrane protein TerC family
KM394_14250	COG1368	sulfuric ester hydrolase activity
KM394_14255	COG0488	(ABC) transporter
KM394_14265	COG1033	growth of symbiont in host cell
KM394_14265	COG2409	Drug exporters of the RND superfamily
KM394_14270	COG1033	growth of symbiont in host cell
KM394_14270	COG2409	Drug exporters of the RND superfamily
KM394_14275	COG1033	growth of symbiont in host cell
KM394_14275	COG2409	Drug exporters of the RND superfamily
KM394_14280	COG1309	transcriptional regulator
KM394_14295	COG0287	Prephenate dehydrogenase
KM394_14300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM394_14305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM394_14310	COG1605	Chorismate mutase
KM394_14310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM394_14345	COG1388	LysM domain
KM394_14345	COG3584	3D domain protein
KM394_14355	COG1595	DNA-templated transcription, initiation
KM394_14380	COG1879	ABC-type sugar transport system periplasmic component
KM394_14390	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM394_14400	COG2390	Transcriptional regulator
KM394_14435	COG2329	Antibiotic biosynthesis monooxygenase
KM394_14455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_14465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM394_14470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM394_14475	COG4187	Peptidase family M20/M25/M40
KM394_14480	COG1414	Transcriptional regulator
KM394_14485	COG0833	amino acid
KM394_14490	COG1690	Belongs to the RtcB family
KM394_14495	COG3239	Fatty acid desaturase
KM394_14500	COG1785	Belongs to the alkaline phosphatase family
KM394_14510	COG3655	Transcriptional regulator
KM394_14525	COG4377	Putative membrane peptidase family (DUF2324)
KM394_14535	COG3279	Response regulator of the LytR AlgR family
KM394_14545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_14550	COG0346	lactoylglutathione lyase activity
KM394_14570	COG0714	Associated with various cellular activities
KM394_14595	COG0463	Glycosyl transferase, family 2
KM394_14620	COG0463	Glycosyl transferase, family 2
KM394_14630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM394_14635	COG0753	catalase activity
KM394_14645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM394_14670	COG0714	Associated with various cellular activities
KM394_14680	COG0778	Nitroreductase
KM394_14685	COG1846	Transcriptional regulator
KM394_14720	COG1725	Transcriptional regulator
KM394_14730	COG0577	efflux transmembrane transporter activity
KM394_14730	COG1136	(ABC) transporter
KM394_14755	COG2207	Transcriptional regulator
KM394_14760	COG0456	acetyltransferase
KM394_14780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_14800	COG0642	Histidine kinase
KM394_14805	COG0745	RESPONSE REGULATOR receiver
KM394_14810	COG0596	Alpha beta hydrolase
KM394_14840	COG0730	response to heat
KM394_14850	COG0833	amino acid
KM394_14860	COG4335	DNA alkylation repair
KM394_14910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM394_14940	COG1984	allophanate hydrolase subunit 2
KM394_14945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM394_14950	COG1414	Transcriptional regulator
KM394_14965	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM394_14970	COG0640	Transcriptional regulator
KM394_14980	COG1960	acyl-CoA dehydrogenase activity
KM394_14995	COG3314	Sporulation integral membrane protein YlbJ
KM394_15010	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM394_15025	COG3848	Pyruvate phosphate dikinase
KM394_15025	COG0574	Belongs to the PEP-utilizing enzyme family
KM394_15030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_15045	COG5577	PFAM Coat F domain
KM394_15050	COG3403	YqcI/YcgG family
KM394_15055	COG1280	lysine exporter protein (LysE YggA)
KM394_15090	COG1063	alcohol dehydrogenase
KM394_15105	COG1027	Aspartate ammonia-lyase
KM394_15110	COG0252	asparaginase activity
KM394_15115	COG1396	sequence-specific DNA binding
KM394_15125	COG0322	excinuclease ABC activity
KM394_15130	COG0531	amino acid
KM394_15135	COG1114	Component of the transport system for branched-chain amino acids
KM394_15140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM394_15150	COG0281	malic enzyme
KM394_15165	COG0531	amino acid
KM394_15175	COG0784	Response regulator, receiver
KM394_15185	COG2066	Belongs to the glutaminase family
KM394_15190	COG1115	amino acid carrier protein
KM394_15220	COG0737	Belongs to the 5'-nucleotidase family
KM394_15225	COG0753	catalase activity
KM394_15230	COG2267	carboxylic ester hydrolase activity
KM394_15235	COG1335	isochorismatase
KM394_15255	COG0583	DNA-binding transcription factor activity
KM394_15260	COG1846	Transcriptional regulator
KM394_15300	COG0415	Belongs to the DNA photolyase family
KM394_15305	COG0288	reversible hydration of carbon dioxide
KM394_15315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM394_15320	COG5609	conserved protein (DUF2294)
KM394_15335	COG1575	Belongs to the MenA family. Type 1 subfamily
KM394_15340	COG2267	carboxylic ester hydrolase activity
KM394_15345	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM394_15350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM394_15355	COG1121	(ABC) transporter
KM394_15385	COG0798	PFAM Bile acid sodium symporter
KM394_15390	COG0346	lactoylglutathione lyase activity
KM394_15395	COG0640	Transcriptional regulator
KM394_15410	COG0443	Heat shock 70 kDa protein
KM394_15425	COG1522	sequence-specific DNA binding
KM394_15440	COG0346	lactoylglutathione lyase activity
KM394_15465	COG2169	Transcriptional regulator
KM394_15510	COG2814	Major facilitator Superfamily
KM394_15535	COG0745	RESPONSE REGULATOR receiver
KM394_15540	COG5002	protein histidine kinase activity
KM394_15540	COG3850	Histidine kinase
KM394_15565	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM394_15585	COG1476	TRANSCRIPTIONal
KM394_15600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_15605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM394_15615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_15620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM394_15635	COG1136	(ABC) transporter
KM394_15640	COG0577	efflux transmembrane transporter activity
KM394_15655	COG5002	protein histidine kinase activity
KM394_15655	COG3850	Histidine kinase
KM394_15665	COG2364	Membrane
KM394_15670	COG1846	Transcriptional regulator
KM394_15680	COG2808	Putative FMN-binding domain
KM394_15685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_15690	COG2271	Major facilitator Superfamily
KM394_15695	COG1556	Lactate utilization protein
KM394_15700	COG1139	Iron-sulfur cluster binding protein
KM394_15710	COG0583	DNA-binding transcription factor activity
KM394_15720	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM394_15745	COG0738	Major facilitator superfamily
KM394_15750	COG0673	inositol 2-dehydrogenase activity
KM394_15755	COG0561	phosphatase activity
KM394_15765	COG1609	Transcriptional regulator
KM394_15770	COG0457	Tetratricopeptide repeat
KM394_15790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM394_15820	COG0534	Mate efflux family protein
KM394_15840	COG2814	Major facilitator Superfamily
KM394_15845	COG1309	transcriptional regulator
KM394_15860	COG0814	amino acid
KM394_15865	COG1760	l-serine dehydratase
KM394_15870	COG1760	l-serine dehydratase
KM394_15880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM394_15885	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM394_15895	COG1335	isochorismatase
KM394_15900	COG1522	sequence-specific DNA binding
KM394_15905	COG0531	amino acid
KM394_15920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM394_15940	COG1595	DNA-templated transcription, initiation
KM394_15955	COG0662	Cupin 2, conserved barrel domain protein
KM394_15960	COG2207	Transcriptional regulator
KM394_15960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_16010	COG0477	Major facilitator Superfamily
KM394_16020	COG1846	Transcriptional regulator
KM394_16025	COG2814	Major facilitator Superfamily
KM394_16035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM394_16040	COG1131	(ABC) transporter
KM394_16060	COG2076	Multidrug Resistance protein
KM394_16065	COG1309	transcriptional regulator
KM394_16075	COG2031	fatty acid transporter
KM394_16085	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM394_16115	COG1122	ATPase activity
KM394_16120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM394_16135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM394_16140	COG1288	antiporter activity
KM394_16145	COG2356	endonuclease I
KM394_16160	COG3620	sequence-specific DNA binding
KM394_16165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM394_16170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM394_16175	COG0124	histidyl-tRNA synthetase
KM394_16190	COG1733	regulation of RNA biosynthetic process
KM394_16195	COG0778	Nitroreductase
KM394_16215	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_16225	COG1131	(ABC) transporter
KM394_16250	COG1011	Hydrolase
KM394_16260	COG2365	Tyrosine phosphatase family
KM394_16285	COG0346	lactoylglutathione lyase activity
KM394_16290	COG1940	carbohydrate kinase activity
KM394_16295	COG0738	Major facilitator superfamily
KM394_16300	COG0110	maltose O-acetyltransferase activity
KM394_16310	COG0577	efflux transmembrane transporter activity
KM394_16310	COG1136	(ABC) transporter
KM394_16325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM394_16330	COG0628	permease
KM394_16350	COG2226	methyltransferase
KM394_16360	COG0477	Major facilitator Superfamily
KM394_16390	COG1253	flavin adenine dinucleotide binding
KM394_16395	COG0789	Transcriptional regulator
KM394_16400	COG0697	spore germination
KM394_16405	COG1357	PFAM Pentapeptide repeats (8 copies)
KM394_16410	COG3813	Protein conserved in bacteria
KM394_16415	COG2706	6-phosphogluconolactonase activity
KM394_16420	COG1070	Carbohydrate kinase
KM394_16430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM394_16435	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM394_16445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM394_16450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM394_16455	COG0604	alcohol dehydrogenase
KM394_16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM394_16470	COG3321	synthase
KM394_16470	COG0604	alcohol dehydrogenase
KM394_16475	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_16500	COG0656	L-ascorbic acid biosynthetic process
KM394_16505	COG2814	Major facilitator Superfamily
KM394_16520	COG0346	lactoylglutathione lyase activity
KM394_16525	COG0814	amino acid
KM394_16550	COG1393	Belongs to the ArsC family
KM394_16555	COG1733	regulation of RNA biosynthetic process
KM394_16560	COG2188	Transcriptional regulator
KM394_16570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM394_16575	COG1733	regulation of RNA biosynthetic process
KM394_16580	COG1733	regulation of RNA biosynthetic process
KM394_16595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_16615	COG0384	phenazine biosynthesis protein PhzF
KM394_16625	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_16635	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_16645	COG1733	regulation of RNA biosynthetic process
KM394_16680	COG1191	sigma factor activity
KM394_16695	COG1309	transcriptional regulator
KM394_16715	COG3152	Membrane
KM394_16740	COG1151	hydroxylamine reductase activity
KM394_16750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_16755	COG3757	hydrolase, family 25
KM394_16755	COG3409	Peptidoglycan-binding domain 1 protein
KM394_16790	COG2072	flavoprotein involved in K transport
KM394_16825	COG0604	alcohol dehydrogenase
KM394_16830	COG1113	amino acid transport
KM394_16835	COG2814	Major facilitator Superfamily
KM394_16865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM394_16870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM394_16890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_16905	COG3739	integral membrane protein
KM394_16910	COG0384	phenazine biosynthesis protein PhzF
KM394_16940	COG0583	DNA-binding transcription factor activity
KM394_16960	COG1193	negative regulation of DNA recombination
KM394_16980	COG1164	Oligoendopeptidase f
KM394_16985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM394_17015	COG0584	glycerophosphoryl diester phosphodiesterase
KM394_17040	COG0640	Transcriptional regulator
KM394_17045	COG0604	alcohol dehydrogenase
KM394_17065	COG2808	Putative FMN-binding domain
KM394_17070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM394_17080	COG0385	Bile acid
KM394_17085	COG0277	FAD linked oxidase domain protein
KM394_17115	COG1216	Glycosyl transferase, family 2
KM394_17120	COG1024	Enoyl-CoA hydratase
KM394_17130	COG1285	pathogenesis
KM394_17145	COG2514	catechol 2,3-dioxygenase activity
KM394_17150	COG2720	vancomycin resistance protein
KM394_17190	COG0716	FMN binding
KM394_17220	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_17230	COG0165	Argininosuccinate lyase
KM394_17245	COG4145	pantothenate transmembrane transporter activity
KM394_17255	COG1012	belongs to the aldehyde dehydrogenase family
KM394_17260	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_17270	COG1657	PFAM Prenyltransferase squalene oxidase
KM394_17275	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM394_17280	COG2962	Rard protein
KM394_17285	COG3326	Membrane
KM394_17300	COG0489	protein tyrosine kinase activity
KM394_17310	COG0314	molybdopterin synthase activity
KM394_17315	COG0303	'Molybdopterin
KM394_17320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM394_17325	COG2116	formate transmembrane transporter activity
KM394_17335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM394_17340	COG5609	conserved protein (DUF2294)
KM394_17345	COG2427	Protein of unknown function (DUF1641)
KM394_17350	COG3383	formate dehydrogenase (NAD+) activity
KM394_17360	COG0697	spore germination
KM394_17400	COG2226	methyltransferase
KM394_17405	COG4166	transmembrane transport
KM394_17410	COG4166	transmembrane transport
KM394_17415	COG4166	transmembrane transport
KM394_17420	COG1301	dicarboxylic acid transport
KM394_17425	COG1316	TRANSCRIPTIONal
KM394_17435	COG1595	DNA-templated transcription, initiation
KM394_17455	COG1131	(ABC) transporter
KM394_17465	COG0673	inositol 2-dehydrogenase activity
KM394_17470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM394_17475	COG0187	DNA topoisomerase II activity
KM394_17480	COG1832	CoA-binding protein
KM394_17485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM394_17490	COG0745	RESPONSE REGULATOR receiver
KM394_17505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM394_17510	COG4841	protein insertion into membrane
KM394_17515	COG0824	Thioesterase
KM394_17545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM394_17555	COG2274	protein secretion by the type I secretion system
KM394_17560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM394_17600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM394_17615	COG0183	Belongs to the thiolase family
KM394_17620	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_17625	COG1268	BioY protein
KM394_17630	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_17680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_17690	COG5002	protein histidine kinase activity
KM394_17695	COG0400	carboxylic ester hydrolase activity
KM394_17700	COG0346	lactoylglutathione lyase activity
KM394_17705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM394_17710	COG0069	glutamate synthase activity
KM394_17715	COG1902	pentaerythritol trinitrate reductase activity
KM394_17720	COG1329	Transcriptional regulator
KM394_17725	COG0010	Belongs to the arginase family
KM394_17750	COG2226	methyltransferase
KM394_17805	COG4846	Membrane protein involved in cytochrome C biogenesis
KM394_17810	COG0785	Cytochrome C biogenesis protein
KM394_17820	COG0583	DNA-binding transcription factor activity
KM394_17825	COG1380	Effector of murein hydrolase LrgA
KM394_17830	COG1346	cytolysis
KM394_17855	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM394_17855	COG3409	Peptidoglycan-binding domain 1 protein
KM394_17870	COG1132	(ABC) transporter
KM394_17875	COG1132	(ABC) transporter
KM394_17905	COG3639	organic phosphonate transmembrane transporter activity
KM394_17910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM394_17930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM394_17950	COG1695	Transcriptional regulator
KM394_17985	COG1388	LysM domain
KM394_17985	COG3409	Peptidoglycan-binding domain 1 protein
KM394_17985	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM394_17990	COG4824	toxin secretion phage lysis holin
KM394_18145	COG1595	DNA-templated transcription, initiation
KM394_18190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM394_18275	COG1396	sequence-specific DNA binding
KM394_18300	COG0174	glutamine synthetase
KM394_18305	COG0789	Transcriptional regulator
KM394_18310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM394_18320	COG2860	membrane
KM394_18330	COG0464	growth
KM394_18360	COG3584	3D domain protein
KM394_18360	COG1388	LysM domain
KM394_18365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM394_18365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM394_18365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM394_18370	COG1105	Belongs to the carbohydrate kinase PfkB family
KM394_18375	COG1349	DNA-binding transcription factor activity
KM394_18385	COG2322	membrane
KM394_18395	COG1113	amino acid transport
KM394_18410	COG1408	metallophosphoesterase
KM394_18415	COG2116	formate transmembrane transporter activity
KM394_18425	COG2217	Heavy metal translocating P-type atpase
KM394_18430	COG2608	mercury ion transmembrane transporter activity
KM394_18435	COG1937	Protein conserved in bacteria
KM394_18445	COG2819	hydrolase of the alpha beta superfamily
KM394_18450	COG1120	ATPase activity
KM394_18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_18470	COG0708	Exodeoxyribonuclease III
KM394_18475	COG2169	Transcriptional regulator
KM394_18480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM394_18485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM394_18495	COG2364	Membrane
KM394_18510	COG2267	carboxylic ester hydrolase activity
KM394_18515	COG0346	lactoylglutathione lyase activity
KM394_18520	COG3300	MHYT domain
KM394_18520	COG5001	Diguanylate cyclase
KM394_18535	COG1346	cytolysis
KM394_18540	COG1380	Effector of murein hydrolase LrgA
KM394_18545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM394_18550	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM394_18550	COG0596	Alpha beta hydrolase
KM394_18555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM394_18575	COG1404	Belongs to the peptidase S8 family
KM394_18580	COG3773	Cell wall hydrolase
KM394_18585	COG0562	UDP-galactopyranose mutase
KM394_18590	COG1368	sulfuric ester hydrolase activity
KM394_18595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM394_18605	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM394_18630	COG1131	(ABC) transporter
KM394_18650	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM394_18655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM394_18660	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM394_18665	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM394_18665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM394_18675	COG2359	stage V sporulation protein S
KM394_18680	COG1692	metallophosphoesterase
KM394_18705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM394_18710	COG1426	Protein conserved in bacteria
KM394_18725	COG0300	oxidoreductase activity
KM394_18730	COG0612	Peptidase, M16
KM394_18735	COG0612	Peptidase, M16
KM394_18740	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM394_18750	COG3845	ABC transporter
KM394_18755	COG1744	ABC transporter substrate-binding protein PnrA-like
KM394_18760	COG2188	Transcriptional regulator
KM394_18765	COG1674	ftsk spoiiie
KM394_18775	COG0740	serine-type endopeptidase activity
KM394_18780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM394_18790	COG0527	aspartate kinase activity
KM394_18795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM394_18800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM394_18805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM394_18810	COG1873	PFAM PRC-barrel domain
KM394_18815	COG0612	Peptidase, M16
KM394_18820	COG0726	polysaccharide deacetylase
KM394_18835	COG0196	riboflavin kinase activity
KM394_18840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM394_18850	COG1550	Protein conserved in bacteria
KM394_18860	COG1358	cellular component organization or biogenesis
KM394_18865	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM394_18870	COG0195	Participates in both transcription termination and antitermination
KM394_18890	COG0750	zinc metalloprotease
KM394_18900	COG4589	Belongs to the CDS family
KM394_18905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM394_18915	COG0528	UMP kinase activity
KM394_18945	COG4974	Belongs to the 'phage' integrase family
KM394_18955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM394_18965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM394_19005	COG1837	Belongs to the UPF0109 family
KM394_19015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM394_19025	COG0552	protein localization to endoplasmic reticulum
KM394_19030	COG1196	nuclear chromosome segregation
KM394_19040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM394_19045	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_19050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM394_19065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM394_19070	COG1461	Dihydroxyacetone kinase
KM394_19075	COG1302	Protein conserved in bacteria
KM394_19090	COG1564	THIamine pyrophosphokinase
KM394_19095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM394_19100	COG1162	GTPase activity
KM394_19105	COG0515	serine threonine protein kinase
KM394_19105	COG2815	serine threonine protein kinase
KM394_19110	COG0631	protein serine/threonine phosphatase activity
KM394_19120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM394_19120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM394_19130	COG0242	peptide deformylase activity
KM394_19135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM394_19140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM394_19160	COG1561	YicC-like family, N-terminal region
KM394_19165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM394_19175	COG0006	proline dipeptidase activity
KM394_19190	COG3069	C4-dicarboxylate transmembrane transporter activity
KM394_19255	COG0564	pseudouridine synthase activity
KM394_19275	COG3599	regulation of cell shape
KM394_19280	COG2302	S4 RNA-binding domain
KM394_19285	COG0762	integral membrane protein
KM394_19295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM394_19300	COG1496	oxidoreductase activity
KM394_19305	COG1873	PFAM PRC-barrel domain
KM394_19310	COG1191	sigma factor activity
KM394_19315	COG1191	sigma factor activity
KM394_19325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM394_19330	COG0849	cell division
KM394_19335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM394_19340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM394_19350	COG0772	Belongs to the SEDS family
KM394_19365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM394_19370	COG0768	penicillin binding
KM394_19375	COG0768	penicillin binding
KM394_19380	COG4839	cell division protein FtsL
KM394_19395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM394_19410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM394_19415	COG1399	metal-binding, possibly nucleic acid-binding protein
KM394_19465	COG4824	toxin secretion phage lysis holin
KM394_19550	COG4626	Terminase
KM394_19550	COG1802	Transcriptional regulator
KM394_19575	COG0582	viral genome integration into host DNA
KM394_19640	COG0756	dUTP diphosphatase activity
KM394_19655	COG1191	sigma factor activity
KM394_19680	COG1484	DNA-dependent DNA replication
KM394_19710	COG1396	sequence-specific DNA binding
KM394_19725	COG1396	sequence-specific DNA binding
KM394_19740	COG0582	viral genome integration into host DNA
KM394_19750	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM394_19755	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM394_19760	COG3314	Sporulation integral membrane protein YlbJ
KM394_19770	COG0742	ribosomal rna small subunit methyltransferase
KM394_19785	COG3679	Belongs to the UPF0342 family
KM394_19790	COG0406	alpha-ribazole phosphatase activity
KM394_19805	COG2340	Cysteine-rich secretory protein family
KM394_19820	COG3336	cytochrome c oxidase
KM394_19855	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM394_19860	COG0772	Belongs to the SEDS family
KM394_19870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM394_19875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM394_19885	COG4896	Protein conserved in bacteria
KM394_19900	COG1217	gtp-binding protein TYPA
KM394_19910	COG0483	inositol monophosphate 1-phosphatase activity
KM394_19930	COG1982	Orn Lys Arg decarboxylase major
KM394_19975	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM394_19980	COG0022	dehydrogenase e1 component
KM394_19985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM394_19995	COG0242	peptide deformylase activity
KM394_20000	COG0561	phosphatase activity
KM394_20010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM394_20015	COG0569	domain protein
KM394_20035	COG0583	DNA-binding transcription factor activity
KM394_20040	COG0517	IMP dehydrogenase activity
KM394_20050	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM394_20060	COG4703	Protein of unknown function (DUF1797)
KM394_20075	COG2200	EAL domain
KM394_20080	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_20085	COG1408	metallophosphoesterase
KM394_20095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM394_20130	COG2814	Major facilitator Superfamily
KM394_20150	COG3209	COG3209 Rhs family protein
KM394_20160	COG2205	protein histidine kinase activity
KM394_20170	COG0436	Aminotransferase
KM394_20175	COG1609	Transcriptional regulator
KM394_20180	COG3833	ABC-type maltose transport systems, permease component
KM394_20185	COG1175	transmembrane transport
KM394_20190	COG2182	Extracellular solute-binding protein
KM394_20200	COG0366	Alpha amylase catalytic
KM394_20205	COG3842	ATPase activity
KM394_20245	COG0183	Belongs to the thiolase family
KM394_20280	COG1695	Transcriptional regulator
KM394_20285	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_20295	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM394_20305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM394_20310	COG0436	Aminotransferase
KM394_20330	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM394_20350	COG2199	diguanylate cyclase activity
KM394_20355	COG0778	Nitroreductase
KM394_20380	COG2190	(PTS) system
KM394_20380	COG1263	PTS System
KM394_20380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM394_20385	COG3711	transcriptional antiterminator
KM394_20395	COG2188	Transcriptional regulator
KM394_20405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM394_20430	COG1547	Domain of unknown function (DUF309)
KM394_20435	COG0456	acetyltransferase
KM394_20440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM394_20445	COG4086	secreted protein
KM394_20450	COG0561	phosphatase activity
KM394_20455	COG0697	spore germination
KM394_20470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_20495	COG0733	neurotransmitter:sodium symporter activity
KM394_20515	COG1686	Belongs to the peptidase S11 family
KM394_20520	COG1725	Transcriptional regulator
KM394_20525	COG1131	(ABC) transporter
KM394_20540	COG1846	Transcriptional regulator
KM394_20555	COG0598	Magnesium transport protein CorA
KM394_20580	COG4974	Belongs to the 'phage' integrase family
KM394_20590	COG0735	belongs to the Fur family
KM394_20595	COG1300	Membrane
KM394_20615	COG0667	Aldo Keto reductase
KM394_20620	COG0656	L-ascorbic acid biosynthetic process
KM394_20625	COG0456	acetyltransferase
KM394_20625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM394_20635	COG0737	Belongs to the 5'-nucleotidase family
KM394_20635	COG1525	nuclease
KM394_20635	COG4085	toxin activity
KM394_20645	COG0596	Alpha beta hydrolase
KM394_20650	COG2056	Na+-H+ antiporter family
KM394_20655	COG1609	Transcriptional regulator
KM394_20660	COG0456	acetyltransferase
KM394_20665	COG1073	alpha beta
KM394_20680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM394_20680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM394_20685	COG0307	riboflavin synthase, alpha
KM394_20710	COG4106	trans-aconitate 2-methyltransferase activity
KM394_20715	COG1073	alpha beta
KM394_20715	COG2226	methyltransferase
KM394_20730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM394_20740	COG1757	Na H antiporter
KM394_20745	COG0737	Belongs to the 5'-nucleotidase family
KM394_20755	COG1522	sequence-specific DNA binding
KM394_20775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM394_20785	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM394_20800	COG0300	oxidoreductase activity
KM394_20810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM394_20815	COG1760	l-serine dehydratase
KM394_20820	COG1760	l-serine dehydratase
KM394_20850	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM394_20855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_20870	COG1376	ErfK ybiS ycfS ynhG family protein
KM394_20875	COG4129	membrane
KM394_20880	COG1126	abc transporter atp-binding protein
KM394_20885	COG0765	amino acid transport
KM394_20890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM394_20910	COG0772	Belongs to the SEDS family
KM394_20915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM394_20920	COG0022	dehydrogenase e1 component
KM394_20925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM394_20930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM394_20945	COG0280	phosphate acetyltransferase
KM394_20950	COG3829	transcription factor binding
KM394_20950	COG3290	protein histidine kinase activity
KM394_20960	COG0584	glycerophosphoryl diester phosphodiesterase
KM394_20965	COG3093	addiction module antidote protein HigA
KM394_20975	COG0745	RESPONSE REGULATOR receiver
KM394_20980	COG0750	zinc metalloprotease
KM394_20985	COG0497	DNA recombination
KM394_20995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM394_21005	COG0142	geranyltranstransferase activity
KM394_21030	COG1302	Protein conserved in bacteria
KM394_21035	COG0439	Biotin carboxylase
KM394_21040	COG0511	ligase activity, forming carbon-carbon bonds
KM394_21085	COG3854	ATPases associated with a variety of cellular activities
KM394_21110	COG0006	proline dipeptidase activity
KM394_21125	COG3872	metal-dependent enzyme
KM394_21135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM394_21155	COG0095	Lipoate-protein ligase
KM394_21160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_21165	COG1609	Transcriptional regulator
KM394_21175	COG2076	Multidrug Resistance protein
KM394_21180	COG2076	Multidrug Resistance protein
KM394_21215	COG1131	(ABC) transporter
KM394_21220	COG1725	Transcriptional regulator
KM394_21250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM394_21305	COG4970	Tfp pilus assembly protein FimT
KM394_21315	COG1459	type II secretion system
KM394_21320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM394_21370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM394_21375	COG1410	methionine synthase
KM394_21375	COG0646	methionine synthase
KM394_21380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM394_21380	COG0646	methionine synthase
KM394_21385	COG0626	cystathionine gamma-synthase activity
KM394_21390	COG0626	cystathionine gamma-synthase activity
KM394_21410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_21420	COG1940	carbohydrate kinase activity
KM394_21425	COG4483	Protein conserved in bacteria
KM394_21430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM394_21435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM394_21440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM394_21445	COG0704	Plays a role in the regulation of phosphate uptake
KM394_21455	COG0581	inorganic phosphate transmembrane transporter activity
KM394_21460	COG0573	inorganic phosphate transmembrane transporter activity
KM394_21465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM394_21470	COG0768	penicillin binding
KM394_21475	COG0477	Major facilitator Superfamily
KM394_21480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM394_21505	COG0735	belongs to the Fur family
KM394_21510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM394_21515	COG1121	(ABC) transporter
KM394_21520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_21550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM394_21555	COG2384	SAM-dependent methyltransferase
KM394_21560	COG2010	Cytochrome c
KM394_21565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM394_21570	COG0358	DNA primase activity
KM394_21585	COG0517	IMP dehydrogenase activity
KM394_21600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM394_21605	COG0295	cytidine deaminase activity
KM394_21610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM394_21620	COG1480	7TM receptor with intracellular HD hydrolase
KM394_21625	COG1702	phosphate starvation-inducible protein PhoH
KM394_21640	COG1610	YqeY-like protein
KM394_21645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM394_21650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM394_21655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM394_21685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM394_21690	COG1733	regulation of RNA biosynthetic process
KM394_21715	COG1466	dna polymerase III delta subunit
KM394_21725	COG0658	competence protein
KM394_21725	COG2333	competence protein COMEC
KM394_21730	COG2131	deaminase
KM394_21735	COG1555	photosystem II stabilization
KM394_21735	COG1596	polysaccharide export
KM394_21740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM394_21745	COG2226	methyltransferase
KM394_21750	COG0799	negative regulation of ribosome biogenesis
KM394_21755	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM394_21765	COG1534	Rna-binding protein
KM394_21775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM394_21780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM394_21805	COG1595	DNA-templated transcription, initiation
KM394_21815	COG0778	Nitroreductase
KM394_21820	COG2357	RelA SpoT domain protein
KM394_21830	COG1785	Belongs to the alkaline phosphatase family
KM394_21840	COG2267	carboxylic ester hydrolase activity
KM394_21875	COG1404	Belongs to the peptidase S8 family
KM394_21880	COG3186	Phenylalanine-4-hydroxylase
KM394_21895	COG2259	Doxx family
KM394_21935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_21945	COG1012	belongs to the aldehyde dehydrogenase family
KM394_21945	COG1454	alcohol dehydrogenase
KM394_21950	COG0626	cystathionine gamma-synthase activity
KM394_21955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM394_21980	COG0768	penicillin binding
KM394_21995	COG0826	peptidase U32
KM394_22000	COG0826	peptidase U32
KM394_22005	COG4122	O-methyltransferase activity
KM394_22010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM394_22030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM394_22040	COG0628	permease
KM394_22060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM394_22070	COG0482	sulfurtransferase activity
KM394_22075	COG1104	cysteine desulfurase activity
KM394_22080	COG1959	2 iron, 2 sulfur cluster binding
KM394_22085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM394_22095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM394_22120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM394_22130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM394_22130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM394_22135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM394_22140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM394_22140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM394_22150	COG2244	polysaccharide biosynthetic process
KM394_22155	COG2323	membrane
KM394_22165	COG1862	Preprotein translocase
KM394_22195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM394_22205	COG0697	spore germination
KM394_22210	COG0697	spore germination
KM394_22215	COG0640	Transcriptional regulator
KM394_22240	COG0157	Belongs to the NadC ModD family
KM394_22245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM394_22250	COG1104	cysteine desulfurase activity
KM394_22255	COG1827	regulation of RNA biosynthetic process
KM394_22260	COG2258	MOSC domain
KM394_22265	COG0077	Prephenate dehydratase
KM394_22270	COG0577	efflux transmembrane transporter activity
KM394_22275	COG0577	efflux transmembrane transporter activity
KM394_22280	COG1136	(ABC) transporter
KM394_22290	COG0745	RESPONSE REGULATOR receiver
KM394_22295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM394_22300	COG3290	protein histidine kinase activity
KM394_22310	COG2868	ribosomal protein
KM394_22320	COG1530	ribonuclease E activity
KM394_22325	COG1994	Peptidase M50
KM394_22330	COG0739	heme binding
KM394_22335	COG2894	cell division
KM394_22355	COG1077	Cell shape determining protein MreB Mrl
KM394_22375	COG0285	dihydrofolate synthase activity
KM394_22380	COG0525	valine-tRNA ligase activity
KM394_22390	COG1388	LysM domain
KM394_22400	COG0113	porphobilinogen synthase activity
KM394_22405	COG1587	Uroporphyrinogen-III synthase
KM394_22415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM394_22425	COG1846	Transcriptional regulator
KM394_22430	COG1764	response to oxidative stress
KM394_22445	COG0470	DNA polymerase III
KM394_22445	COG1067	ATP-dependent peptidase activity
KM394_22490	COG0622	Phosphoesterase
KM394_22505	COG5401	PFAM Sporulation and spore germination
KM394_22525	COG1309	transcriptional regulator
KM394_22540	COG2197	response regulator
KM394_22545	COG2233	PERMEase
KM394_22555	COG0402	S-adenosylhomocysteine deaminase activity
KM394_22560	COG0402	S-adenosylhomocysteine deaminase activity
KM394_22570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM394_22580	COG0444	Belongs to the ABC transporter superfamily
KM394_22585	COG4608	Belongs to the ABC transporter superfamily
KM394_22590	COG3275	phosphorelay sensor kinase activity
KM394_22595	COG3279	Response regulator of the LytR AlgR family
KM394_22610	COG1983	PspC domain protein
KM394_22615	COG1396	sequence-specific DNA binding
KM394_22620	COG0697	spore germination
KM394_22630	COG1959	2 iron, 2 sulfur cluster binding
KM394_22635	COG1668	transmembrane transport
KM394_22640	COG4152	abc transporter atp-binding protein
KM394_22645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM394_22655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM394_22660	COG1876	peptidase activity
KM394_22665	COG0824	Thioesterase
KM394_22670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM394_22675	COG1053	succinate dehydrogenase
KM394_22680	COG2009	succinate dehydrogenase
KM394_22685	COG1719	4-vinyl reductase, 4VR
KM394_22695	COG3118	belongs to the thioredoxin family
KM394_22700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM394_22705	COG2086	electron transfer activity
KM394_22710	COG1024	Enoyl-CoA hydratase
KM394_22715	COG1309	transcriptional regulator
KM394_22720	COG0318	PFAM AMP-dependent synthetase and ligase
KM394_22740	COG2318	DinB family
KM394_22770	COG1131	(ABC) transporter
KM394_22775	COG2205	protein histidine kinase activity
KM394_22780	COG0745	RESPONSE REGULATOR receiver
KM394_22790	COG4895	conserved protein (DUF2196)
KM394_22795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM394_22810	COG4509	Sortase family
KM394_22815	COG1120	ATPase activity
KM394_22830	COG5386	Cell surface protein
KM394_22840	COG5386	Cell surface protein
KM394_22845	COG1114	Component of the transport system for branched-chain amino acids
KM394_22850	COG1187	pseudouridine synthase activity
KM394_22860	COG1796	DNA polymerase
KM394_22860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM394_22865	COG1286	toxin biosynthetic process
KM394_22910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM394_22920	COG1418	mRNA catabolic process
KM394_22945	COG2814	Major facilitator Superfamily
KM394_22950	COG1566	PFAM secretion protein HlyD family protein
KM394_22955	COG1309	transcriptional regulator
KM394_22960	COG1363	Peptidase, m42
KM394_22985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM394_22995	COG1484	DNA-dependent DNA replication
KM394_23000	COG3611	Membrane attachment protein
KM394_23010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM394_23015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM394_23020	COG0237	dephospho-CoA kinase activity
KM394_23025	COG1971	Probably functions as a manganese efflux pump
KM394_23035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM394_23035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM394_23040	COG5002	protein histidine kinase activity
KM394_23045	COG0745	RESPONSE REGULATOR receiver
KM394_23065	COG0538	isocitrate dehydrogenase activity
KM394_23070	COG0372	Belongs to the citrate synthase family
KM394_23080	COG0628	permease
KM394_23085	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM394_23110	COG1725	Transcriptional regulator
KM394_23115	COG0281	malic enzyme
KM394_23120	COG0587	DNA-directed DNA polymerase activity
KM394_23135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM394_23155	COG4109	DRTGG domain
KM394_23170	COG0006	proline dipeptidase activity
KM394_23205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_23210	COG0662	Cupin 2, conserved barrel domain protein
KM394_23220	COG1476	TRANSCRIPTIONal
KM394_23235	COG1028	Short-chain dehydrogenase reductase Sdr
KM394_23240	COG0589	response to stress
KM394_23280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_23300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM394_23305	COG0827	DNA restriction-modification system
KM394_23310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM394_23315	COG3874	Sporulation protein YtfJ
KM394_23330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM394_23340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM394_23355	COG1104	cysteine desulfurase activity
KM394_23365	COG0583	DNA-binding transcription factor activity
KM394_23370	COG0697	spore germination
KM394_23380	COG1956	GAF domain-containing protein
KM394_23385	COG0626	cystathionine gamma-synthase activity
KM394_23415	COG1595	DNA-templated transcription, initiation
KM394_23425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM394_23430	COG0454	-acetyltransferase
KM394_23435	COG0517	IMP dehydrogenase activity
KM394_23440	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM394_23450	COG0745	RESPONSE REGULATOR receiver
KM394_23460	COG0666	response to abiotic stimulus
KM394_23495	COG1609	Transcriptional regulator
KM394_23500	COG4851	CamS sex pheromone cAM373 precursor
KM394_23505	COG3118	belongs to the thioredoxin family
KM394_23515	COG2309	aminopeptidase activity
KM394_23535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_23550	COG1674	ftsk spoiiie
KM394_23560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM394_23565	COG4848	Belongs to the UPF0354 family
KM394_23570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM394_23575	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM394_23580	COG1363	Peptidase, m42
KM394_23590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_23605	COG0510	thiamine kinase activity
KM394_23610	COG1523	belongs to the glycosyl hydrolase 13 family
KM394_23625	COG1349	DNA-binding transcription factor activity
KM394_23630	COG1187	pseudouridine synthase activity
KM394_23635	COG2244	polysaccharide biosynthetic process
KM394_23640	COG2081	HI0933 family
KM394_23645	COG2814	Major facilitator Superfamily
KM394_23655	COG3832	glyoxalase III activity
KM394_23675	COG1329	Transcriptional regulator
KM394_23685	COG4975	Glucose uptake
KM394_23700	COG0314	molybdopterin synthase activity
KM394_23705	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM394_23710	COG0303	'Molybdopterin
KM394_23720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM394_23725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM394_23745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM394_23755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM394_23800	COG2814	Major facilitator Superfamily
KM394_23805	COG0475	glutathione-regulated potassium exporter activity
KM394_23810	COG0490	domain, Protein
KM394_23815	COG0582	viral genome integration into host DNA
KM394_23825	COG1136	(ABC) transporter
KM394_23845	COG1242	4 iron, 4 sulfur cluster binding
KM394_23850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM394_23855	COG1131	(ABC) transporter
KM394_23865	COG1794	racemase activity, acting on amino acids and derivatives
KM394_23885	COG2267	carboxylic ester hydrolase activity
KM394_23890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM394_23895	COG0671	phosphoesterase, PA-phosphatase related
KM394_23900	COG0438	transferase activity, transferring glycosyl groups
KM394_23910	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM394_23965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM394_23970	COG5002	protein histidine kinase activity
KM394_23975	COG4191	Histidine kinase
KM394_23980	COG2267	carboxylic ester hydrolase activity
KM394_24000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM394_24005	COG1116	anion transmembrane transporter activity
KM394_24010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM394_24035	COG0494	nUDIX hydrolase
KM394_24065	COG0288	reversible hydration of carbon dioxide
KM394_24070	COG1271	oxidase subunit
KM394_24075	COG1294	oxidase, subunit
KM394_24095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_24120	COG1842	Phage shock protein A
KM394_24150	COG5002	protein histidine kinase activity
KM394_24155	COG0745	RESPONSE REGULATOR receiver
KM394_24185	COG1597	lipid kinase activity
KM394_24220	COG0586	Pfam SNARE associated Golgi protein
KM394_24230	COG0577	efflux transmembrane transporter activity
KM394_24235	COG1136	(ABC) transporter
KM394_24240	COG3708	Transcriptional regulator
KM394_24240	COG2207	Transcriptional regulator
KM394_24245	COG0745	RESPONSE REGULATOR receiver
KM394_24250	COG2205	protein histidine kinase activity
KM394_24255	COG0577	efflux transmembrane transporter activity
KM394_24265	COG0577	efflux transmembrane transporter activity
KM394_24270	COG1136	(ABC) transporter
KM394_24290	COG2188	Transcriptional regulator
KM394_24310	COG3964	amidohydrolase
KM394_24340	COG4948	Mandelate Racemase Muconate Lactonizing
KM394_24350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM394_24355	COG0596	Alpha beta hydrolase
KM394_24360	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM394_24365	COG1169	isochorismate synthase
KM394_24370	COG1575	Belongs to the MenA family. Type 1 subfamily
KM394_24375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM394_24395	COG0058	SHG alpha-glucan phosphorylase activity
KM394_24400	COG0297	glycogen (starch) synthase activity
KM394_24405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM394_24525	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM394_24560	COG1285	pathogenesis
KM394_24565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM394_24575	COG0166	Belongs to the GPI family
KM394_24580	COG2155	Conserved Protein
KM394_24585	COG1098	S1 RNA binding domain
KM394_24590	COG0436	Aminotransferase
KM394_24595	COG1522	sequence-specific DNA binding
KM394_24600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM394_24605	COG2267	carboxylic ester hydrolase activity
KM394_24615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM394_24635	COG5018	Exonuclease
KM394_24640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM394_24660	COG2050	protein possibly involved in aromatic compounds catabolism
KM394_24670	COG1268	BioY protein
KM394_24680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM394_24685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM394_24700	COG3584	3D domain protein
KM394_24715	COG1252	NADH dehydrogenase
KM394_24730	COG3708	Transcriptional regulator
KM394_24745	COG1683	Conserved Protein
KM394_24765	COG0316	Belongs to the HesB IscA family
KM394_24780	COG1252	NADH dehydrogenase
KM394_24795	COG0390	transport system, permease component
KM394_24800	COG2824	Alkylphosphonate utilization operon protein PhnA
KM394_24840	COG4837	Protein of unknown function (DUF1462)
KM394_24845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM394_24855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM394_24860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM394_24870	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM394_24875	COG0647	UMP catabolic process
KM394_24885	COG2445	Protein of unknown function DUF86
KM394_24890	COG1494	fructose-1,6-bisphosphatase
KM394_24905	COG4470	Protein conserved in bacteria
KM394_24915	COG0789	Transcriptional regulator
KM394_24920	COG4377	Putative membrane peptidase family (DUF2324)
KM394_24945	COG0739	heme binding
KM394_24955	COG3377	Domain of unknown function (DUF1805)
KM394_24960	COG0737	Belongs to the 5'-nucleotidase family
KM394_24965	COG1695	Transcriptional regulator
KM394_24975	COG0719	Fe-S assembly protein
KM394_24980	COG0822	iron-sulfur transferase activity
KM394_24985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM394_24990	COG0719	Fe-S assembly protein
KM394_24995	COG0396	ATPase activity
KM394_25000	COG1464	Belongs to the NlpA lipoprotein family
KM394_25005	COG1464	Belongs to the NlpA lipoprotein family
KM394_25010	COG2011	ABC-type metal ion transport system permease component
KM394_25015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM394_25025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM394_25030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM394_25040	COG1393	Belongs to the ArsC family
KM394_25085	COG0039	L-malate dehydrogenase activity
KM394_25105	COG1309	transcriptional regulator
KM394_25110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM394_25115	COG1960	acyl-CoA dehydrogenase activity
KM394_25120	COG0183	Belongs to the thiolase family
KM394_25125	COG1024	Enoyl-CoA hydratase
KM394_25125	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM394_25135	COG1686	Belongs to the peptidase S11 family
KM394_25150	COG0011	TIGRFAM Protein of
KM394_25155	COG0840	transmembrane signaling receptor activity
KM394_25175	COG2814	Major facilitator Superfamily
KM394_25180	COG0531	amino acid
KM394_25190	COG0706	membrane insertase activity
KM394_25200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM394_25235	COG0586	Pfam SNARE associated Golgi protein
KM394_25245	COG1376	ErfK ybiS ycfS ynhG family protein
KM394_25250	COG0745	RESPONSE REGULATOR receiver
KM394_25255	COG5002	protein histidine kinase activity
KM394_25275	COG0840	transmembrane signaling receptor activity
KM394_25280	COG2151	metal-sulfur cluster biosynthetic enzyme
KM394_25285	COG3227	Zinc metalloprotease (Elastase)
KM394_25290	COG1741	Belongs to the pirin family
KM394_25305	COG0475	glutathione-regulated potassium exporter activity
KM394_25310	COG0490	domain, Protein
KM394_25315	COG1115	amino acid carrier protein
KM394_25320	COG0783	Belongs to the Dps family
KM394_25335	COG1611	Belongs to the LOG family
KM394_25355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_25360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_25365	COG1115	amino acid carrier protein
KM394_25370	COG1115	amino acid carrier protein
KM394_25375	COG2910	NAD(P)H-binding
KM394_25390	COG0656	L-ascorbic acid biosynthetic process
KM394_25395	COG2814	Major facilitator Superfamily
KM394_25400	COG1733	regulation of RNA biosynthetic process
KM394_25410	COG1252	NADH dehydrogenase
KM394_25415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM394_25420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM394_25430	COG3290	protein histidine kinase activity
KM394_25430	COG0840	transmembrane signaling receptor activity
KM394_25440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM394_25445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM394_25460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM394_25515	COG0557	exoribonuclease II activity
KM394_25520	COG1647	Serine aminopeptidase, S33
KM394_25525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM394_25530	COG1346	cytolysis
KM394_25635	COG4695	Portal protein
KM394_25660	COG4974	Belongs to the 'phage' integrase family
KM394_25670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM394_25675	COG0149	triose-phosphate isomerase activity
KM394_25685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM394_25700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM394_25725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM394_25740	COG2323	membrane
KM394_25745	COG0740	serine-type endopeptidase activity
KM394_25750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM394_25760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM394_25770	COG1051	belongs to the nudix hydrolase family
KM394_25780	COG0492	ferredoxin-NADP+ reductase activity
KM394_25785	COG0457	Tetratricopeptide repeat
KM394_25790	COG0110	maltose O-acetyltransferase activity
KM394_25810	COG1950	PFAM Membrane protein of
KM394_25820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM394_25825	COG0556	nucleotide-excision repair
KM394_25845	COG0789	Transcriptional regulator
KM394_25870	COG2855	membrane
KM394_25875	COG0583	DNA-binding transcription factor activity
KM394_25885	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM394_25890	COG0488	(ABC) transporter
KM394_25900	COG1132	(ABC) transporter
KM394_25905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM394_25910	COG0793	Belongs to the peptidase S41A family
KM394_25910	COG3409	Peptidoglycan-binding domain 1 protein
KM394_25915	COG2177	Part of the ABC transporter FtsEX involved in
KM394_25920	COG2884	Cell division ATP-binding protein ftsE
KM394_25935	COG0653	protein targeting
KM394_25940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM394_25945	COG1278	Cold shock
KM394_25950	COG1040	competence protein
KM394_25955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM394_25960	COG0791	NLP P60 protein
KM394_25960	COG1388	LysM domain
KM394_25965	COG1733	regulation of RNA biosynthetic process
KM394_25970	COG1307	EDD domain protein, DegV family
KM394_25975	COG1739	Uncharacterized protein family UPF0029
KM394_25980	COG1316	TRANSCRIPTIONal
KM394_25985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM394_25990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM394_25995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM394_26005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM394_26005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM394_26020	COG3394	polysaccharide catabolic process
KM394_26025	COG1486	melibiose metabolic process
KM394_26030	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM394_26035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM394_26045	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM394_26050	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM394_26055	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM394_26065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM394_26070	COG1301	dicarboxylic acid transport
KM394_26080	COG0346	lactoylglutathione lyase activity
KM394_26085	COG1511	domain protein
KM394_26090	COG0583	DNA-binding transcription factor activity
KM394_26095	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM394_26110	COG1271	oxidase subunit
KM394_26115	COG1294	oxidase, subunit
KM394_26120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM394_26130	COG1620	l-lactate permease
KM394_26140	COG2389	metal-binding protein
KM394_26150	COG1368	sulfuric ester hydrolase activity
KM394_26165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM394_26175	COG1215	transferase activity, transferring glycosyl groups
KM394_26180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM394_26185	COG3584	3D domain protein
KM394_26185	COG1388	LysM domain
KM394_26210	COG4715	Zinc finger, swim domain protein
KM394_26215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM394_26255	COG0577	efflux transmembrane transporter activity
KM394_26260	COG1136	(ABC) transporter
KM394_26295	COG5002	protein histidine kinase activity
KM394_26300	COG0745	RESPONSE REGULATOR receiver
KM394_26305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM394_26320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM394_26325	COG1134	teichoic acid transport
KM394_26330	COG1682	transport, permease protein
KM394_26335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM394_26380	COG1609	Transcriptional regulator
KM394_26395	COG0739	heme binding
KM394_26415	COG2385	sporulation resulting in formation of a cellular spore
KM394_26430	COG4836	Membrane
KM394_26435	COG1007	ATP synthesis coupled electron transport
KM394_26440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM394_26445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM394_26455	COG0839	Belongs to the complex I subunit 6 family
KM394_26470	COG0649	NAD binding
KM394_26475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM394_26490	COG5001	Diguanylate cyclase
KM394_26490	COG3300	MHYT domain
KM394_26540	COG0356	it plays a direct role in the translocation of protons across the membrane
KM394_26575	COG0698	ribose 5-phosphate isomerase
KM394_26585	COG2190	(PTS) system
KM394_26590	COG2259	Doxx family
KM394_26595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM394_26610	COG0009	L-threonylcarbamoyladenylate synthase
KM394_26625	COG2890	protein-(glutamine-N5) methyltransferase activity
KM394_26645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM394_26650	COG1494	fructose-1,6-bisphosphatase
KM394_26670	COG4821	SIS domain
KM394_26680	COG3343	RNA polymerase activity
KM394_26690	COG1960	acyl-CoA dehydrogenase activity
KM394_26695	COG1960	acyl-CoA dehydrogenase activity
KM394_26700	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM394_26705	COG0183	Belongs to the thiolase family
KM394_26710	COG0247	lactate metabolic process
KM394_26710	COG2181	nitrate reductase activity
KM394_26715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM394_26725	COG5001	Diguanylate cyclase
KM394_26725	COG3300	MHYT domain
KM394_26745	COG2197	response regulator
KM394_26750	COG4585	Histidine kinase
KM394_26755	COG0842	Transport permease protein
KM394_26760	COG1131	(ABC) transporter
KM394_26765	COG0024	Methionine aminopeptidase
KM394_26775	COG2234	aminopeptidase activity
KM394_26795	COG1595	DNA-templated transcription, initiation
KM394_26800	COG0018	arginyl-trna synthetase
KM394_26805	COG4506	Protein conserved in bacteria
KM394_26810	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM394_26825	COG0010	Belongs to the arginase family
KM394_26835	COG2814	Major facilitator Superfamily
KM394_26840	COG0789	Transcriptional regulator
KM394_26845	COG0584	glycerophosphoryl diester phosphodiesterase
KM394_26850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM394_26860	COG1994	Peptidase M50
KM394_26870	COG1078	dGTPase activity
KM394_26875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM394_26880	COG1120	ATPase activity
KM394_26885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM394_26910	COG0095	Lipoate-protein ligase
KM394_26915	COG0280	phosphate acetyltransferase
KM394_26930	COG3773	Cell wall hydrolase
KM394_26940	COG2363	Small membrane protein
KM394_26950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM394_26955	COG2233	PERMEase
KM394_26960	COG0561	phosphatase activity
KM394_26965	COG2814	Major facilitator Superfamily
KM394_26975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM394_26980	COG1131	(ABC) transporter
KM394_26985	COG2755	lipolytic protein G-D-S-L family
KM394_26990	COG1609	Transcriptional regulator
KM394_27000	COG0460	homoserine dehydrogenase
KM394_27010	COG2873	o-acetylhomoserine
KM394_27020	COG1011	Hydrolase
KM394_27025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM394_27035	COG2197	response regulator
KM394_27045	COG0351	phosphomethylpyrimidine kinase
KM394_27050	COG3706	GGDEF domain
KM394_27055	COG2879	small protein
KM394_27060	COG1966	Carbon starvation protein
KM394_27065	COG3279	Response regulator of the LytR AlgR family
KM394_27070	COG0477	Major facilitator Superfamily
KM394_27095	COG0840	transmembrane signaling receptor activity
KM394_27105	COG1607	acyl-coa hydrolase
KM394_27120	COG0488	(ABC) transporter
KM394_27140	COG0463	Glycosyl transferase, family 2
KM394_27145	COG1309	transcriptional regulator
KM394_27150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM394_27155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM394_27155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM394_27160	COG0628	permease
KM394_27175	COG3279	Response regulator of the LytR AlgR family
KM394_27180	COG3275	phosphorelay sensor kinase activity
KM394_27185	COG2814	Major facilitator Superfamily
KM394_27190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM394_27195	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM394_27200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM394_27220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM394_27225	COG1272	protein, Hemolysin III
KM394_27245	COG0516	GMP reductase activity
KM394_27250	COG1164	Oligoendopeptidase f
KM394_27270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM394_27275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM394_27280	COG4853	Protein conserved in bacteria
KM394_27285	COG4863	YycH protein
KM394_27290	COG5002	protein histidine kinase activity
KM394_27295	COG0745	RESPONSE REGULATOR receiver
KM394_27325	COG0305	Participates in initiation and elongation during chromosome replication
KM394_27335	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM394_27340	COG4241	membrane
KM394_27350	COG0629	single-stranded DNA binding
KM394_27360	COG0012	GTP binding
KM394_27365	COG4481	Protein conserved in bacteria
KM394_27370	COG0668	transmembrane transport
KM394_27380	COG1475	DNA binding
KM394_27385	COG1192	Involved in chromosome partitioning
KM394_27410	COG1847	R3H domain protein
KM394_27415	COG0706	membrane insertase activity
KM394_27425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM394_27480	COG3344	reverse transcriptase
KM394_27560	COG3344	reverse transcriptase
KM394_27755	COG4962	Type ii secretion system protein e
KM394_27890	COG2311	Membrane
KM394_27910	COG4196	transglutaminase domain protein
KM394_27915	COG0671	phosphoesterase, PA-phosphatase related
KM394_27930	COG1215	transferase activity, transferring glycosyl groups
KM394_27935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM394_27940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM394_28100	COG2002	toxin-antitoxin pair type II binding
KM394_28110	COG4974	Belongs to the 'phage' integrase family
KM394_28165	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM394_28175	COG4974	Belongs to the 'phage' integrase family
KM394_28200	COG0457	Tetratricopeptide repeat
KM394_28400	COG0741	lytic transglycosylase activity
KM394_28400	COG0791	NLP P60 protein
KM394_28465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM394_28525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM394_28535	COG4166	transmembrane transport
KM394_28570	COG1280	lysine exporter protein (LysE YggA)
KM394_28595	COG0681	Belongs to the peptidase S26 family
KM394_28670	COG1309	transcriptional regulator
KM394_28675	COG1683	Conserved Protein
KM394_28720	COG1192	Involved in chromosome partitioning