locus-tag	class	description
KM414_00010	COG0592	DNA-directed DNA polymerase activity
KM414_00015	COG2501	S4 domain
KM414_00025	COG0187	DNA topoisomerase II activity
KM414_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM414_00065	COG0516	GMP reductase activity
KM414_00065	COG0517	IMP dehydrogenase activity
KM414_00070	COG1686	Belongs to the peptidase S11 family
KM414_00100	COG1428	Deoxynucleoside kinase
KM414_00105	COG1428	Deoxynucleoside kinase
KM414_00110	COG1335	isochorismatase
KM414_00115	COG0590	tRNA wobble adenosine to inosine editing
KM414_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM414_00180	COG1982	Orn Lys Arg decarboxylase major
KM414_00190	COG0470	DNA polymerase III
KM414_00195	COG1774	PSP1 C-terminal conserved region
KM414_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM414_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM414_00220	COG2002	toxin-antitoxin pair type II binding
KM414_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM414_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM414_00230	COG0084	hydrolase, TatD family'
KM414_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM414_00250	COG4466	Protein conserved in bacteria
KM414_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM414_00270	COG0251	oxidation-reduction process
KM414_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM414_00305	COG2002	toxin-antitoxin pair type II binding
KM414_00310	COG2244	polysaccharide biosynthetic process
KM414_00315	COG3956	TIGRFAM MazG family protein
KM414_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM414_00340	COG1098	S1 RNA binding domain
KM414_00355	COG2208	phosphoserine phosphatase activity
KM414_00360	COG0037	tRNA processing
KM414_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM414_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM414_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM414_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM414_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM414_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM414_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM414_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM414_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM414_00420	COG1396	sequence-specific DNA binding
KM414_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM414_00455	COG3880	PFAM UvrB UvrC protein
KM414_00465	COG0542	response to heat
KM414_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM414_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM414_00500	COG1045	serine acetyltransferase
KM414_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM414_00520	COG3688	RNA-binding protein containing a PIN domain
KM414_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM414_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM414_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM414_00565	COG2813	Specifically methylates the guanine in position
KM414_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM414_00580	COG1358	cellular component organization or biogenesis
KM414_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM414_00710	COG0201	protein transport
KM414_00720	COG0024	Methionine aminopeptidase
KM414_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM414_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM414_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM414_00795	COG0489	protein tyrosine kinase activity
KM414_00805	COG2194	sulfuric ester hydrolase activity
KM414_00810	COG0726	polysaccharide deacetylase
KM414_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM414_00895	COG4856	YbbR-like protein
KM414_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM414_00915	COG0596	Alpha beta hydrolase
KM414_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM414_00940	COG4946	Tricorn protease homolog
KM414_00940	COG1506	peptidase
KM414_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM414_00975	COG2011	ABC-type metal ion transport system permease component
KM414_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM414_00985	COG1464	Belongs to the NlpA lipoprotein family
KM414_00990	COG0604	alcohol dehydrogenase
KM414_01000	COG0277	FAD linked oxidase domain protein
KM414_01005	COG2271	Major facilitator Superfamily
KM414_01015	COG2814	Major facilitator Superfamily
KM414_01030	COG0601	transmembrane transport
KM414_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM414_01040	COG0444	Belongs to the ABC transporter superfamily
KM414_01045	COG4608	Belongs to the ABC transporter superfamily
KM414_01050	COG4166	transmembrane transport
KM414_01060	COG2207	Transcriptional regulator
KM414_01075	COG4166	transmembrane transport
KM414_01080	COG4166	transmembrane transport
KM414_01085	COG0656	L-ascorbic acid biosynthetic process
KM414_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM414_01105	COG4149	molybdate abc transporter
KM414_01115	COG1910	domain protein
KM414_01125	COG0583	DNA-binding transcription factor activity
KM414_01130	COG0697	spore germination
KM414_01145	COG0204	Acyl-transferase
KM414_01155	COG1609	Transcriptional regulator
KM414_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_01175	COG0084	hydrolase, TatD family'
KM414_01180	COG5298	Protein conserved in bacteria
KM414_01205	COG0488	(ABC) transporter
KM414_01220	COG0747	negative chemotaxis
KM414_01225	COG0601	transmembrane transport
KM414_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM414_01235	COG0444	Belongs to the ABC transporter superfamily
KM414_01240	COG4608	Belongs to the ABC transporter superfamily
KM414_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM414_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM414_01290	COG2814	Major facilitator Superfamily
KM414_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM414_01310	COG4294	response to UV
KM414_01315	COG0457	Tetratricopeptide repeat
KM414_01315	COG0705	Rhomboid family
KM414_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM414_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM414_01335	COG0864	Transcriptional regulator
KM414_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM414_01345	COG2183	response to ionizing radiation
KM414_01440	COG0802	atpase or kinase
KM414_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM414_01450	COG0456	acetyltransferase
KM414_01460	COG0488	(ABC) transporter
KM414_01475	COG1266	CAAX protease self-immunity
KM414_01495	COG2252	PERMEase
KM414_01505	COG5002	protein histidine kinase activity
KM414_01535	COG2226	methyltransferase
KM414_01575	COG1968	undecaprenyl-diphosphatase activity
KM414_01590	COG2205	protein histidine kinase activity
KM414_01595	COG0745	RESPONSE REGULATOR receiver
KM414_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM414_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM414_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM414_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM414_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM414_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM414_01670	COG0151	Belongs to the GarS family
KM414_01695	COG0210	DNA helicase
KM414_01705	COG4851	CamS sex pheromone cAM373 precursor
KM414_01725	COG1335	isochorismatase
KM414_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM414_01735	COG2011	ABC-type metal ion transport system permease component
KM414_01740	COG1464	Belongs to the NlpA lipoprotein family
KM414_01760	COG1846	Transcriptional regulator
KM414_01785	COG1597	lipid kinase activity
KM414_01790	COG0546	phosphoglycolate phosphatase activity
KM414_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM414_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM414_01810	COG2076	Multidrug Resistance protein
KM414_01815	COG2309	aminopeptidase activity
KM414_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM414_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM414_01850	COG4807	Protein conserved in bacteria
KM414_01875	COG1757	Na H antiporter
KM414_01880	COG1473	amidohydrolase
KM414_01895	COG0450	alkyl hydroperoxide reductase
KM414_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_01940	COG0166	Belongs to the GPI family
KM414_01975	COG5002	protein histidine kinase activity
KM414_01995	COG3541	Predicted nucleotidyltransferase
KM414_02000	COG2814	Major facilitator Superfamily
KM414_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM414_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM414_02015	COG0765	amino acid transport
KM414_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM414_02030	COG0840	transmembrane signaling receptor activity
KM414_02035	COG0840	transmembrane signaling receptor activity
KM414_02040	COG0366	Alpha amylase catalytic
KM414_02045	COG2190	(PTS) system
KM414_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_02045	COG1263	PTS System
KM414_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM414_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM414_02100	COG1116	anion transmembrane transporter activity
KM414_02105	COG0488	(ABC) transporter
KM414_02150	COG2270	Major facilitator Superfamily
KM414_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM414_02180	COG2310	stress, protein
KM414_02185	COG2310	stress, protein
KM414_02190	COG2310	stress, protein
KM414_02195	COG0861	Integral membrane protein TerC family
KM414_02205	COG3853	Toxic anion resistance protein (TelA)
KM414_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM414_02230	COG1295	ribonuclease BN
KM414_02235	COG2217	Heavy metal translocating P-type atpase
KM414_02240	COG0697	spore germination
KM414_02260	COG0586	Pfam SNARE associated Golgi protein
KM414_02275	COG3871	stress protein (general stress protein 26)
KM414_02280	COG0387	Pfam Sodium calcium exchanger
KM414_02290	COG0535	radical SAM domain protein
KM414_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM414_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM414_02325	COG0582	viral genome integration into host DNA
KM414_02335	COG1396	sequence-specific DNA binding
KM414_02350	COG1396	sequence-specific DNA binding
KM414_02385	COG1484	DNA-dependent DNA replication
KM414_02615	COG0101	tRNA pseudouridine synthase activity
KM414_02625	COG3829	transcription factor binding
KM414_02635	COG0833	amino acid
KM414_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM414_02670	COG1263	PTS System
KM414_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM414_02690	COG0463	Glycosyl transferase, family 2
KM414_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM414_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM414_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM414_02745	COG1228	amidohydrolase
KM414_02750	COG1090	epimerase
KM414_02780	COG1988	membrane-bound metal-dependent
KM414_02785	COG1194	a g-specific adenine glycosylase
KM414_02810	COG1132	(ABC) transporter
KM414_02815	COG4129	membrane
KM414_02820	COG0067	glutamate synthase
KM414_02820	COG0070	glutamate synthase
KM414_02820	COG0069	glutamate synthase activity
KM414_02830	COG4555	ABC transporter
KM414_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM414_02855	COG0735	belongs to the Fur family
KM414_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM414_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM414_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM414_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM414_03005	COG2766	serine protein kinase
KM414_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM414_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM414_03040	COG2268	Band 7 protein
KM414_03050	COG3290	protein histidine kinase activity
KM414_03055	COG4565	transcriptional regulatory protein
KM414_03060	COG2851	Citrate transporter
KM414_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM414_03085	COG3842	ATPase activity
KM414_03090	COG1175	transmembrane transport
KM414_03095	COG0395	ABC-type sugar transport system, permease component
KM414_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM414_03110	COG0745	RESPONSE REGULATOR receiver
KM414_03115	COG5002	protein histidine kinase activity
KM414_03125	COG4990	cell redox homeostasis
KM414_03135	COG3290	protein histidine kinase activity
KM414_03140	COG4565	transcriptional regulatory protein
KM414_03145	COG3493	citrate carrier protein
KM414_03150	COG0281	malic enzyme
KM414_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_03175	COG5002	protein histidine kinase activity
KM414_03180	COG0745	RESPONSE REGULATOR receiver
KM414_03185	COG0456	acetyltransferase
KM414_03185	COG0454	-acetyltransferase
KM414_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM414_03195	COG3383	formate dehydrogenase (NAD+) activity
KM414_03200	COG2427	Protein of unknown function (DUF1641)
KM414_03215	COG0531	amino acid
KM414_03220	COG0640	Transcriptional regulator
KM414_03225	COG2217	Heavy metal translocating P-type atpase
KM414_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM414_03245	COG3227	Zinc metalloprotease (Elastase)
KM414_03265	COG2720	vancomycin resistance protein
KM414_03270	COG1316	TRANSCRIPTIONal
KM414_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_03280	COG0346	lactoylglutathione lyase activity
KM414_03285	COG1253	flavin adenine dinucleotide binding
KM414_03290	COG1027	Aspartate ammonia-lyase
KM414_03295	COG1620	l-lactate permease
KM414_03310	COG3104	oligopeptide transport
KM414_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_03335	COG2226	methyltransferase
KM414_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM414_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM414_03355	COG4548	von Willebrand factor, type A
KM414_03360	COG0714	Associated with various cellular activities
KM414_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM414_03385	COG0531	amino acid
KM414_03390	COG2188	Transcriptional regulator
KM414_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_03395	COG1263	PTS System
KM414_03400	COG0366	Alpha amylase catalytic
KM414_03415	COG0697	spore germination
KM414_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM414_03430	COG1115	amino acid carrier protein
KM414_03435	COG1126	abc transporter atp-binding protein
KM414_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM414_03445	COG0765	amino acid transport
KM414_03450	COG0765	amino acid transport
KM414_03455	COG0833	amino acid
KM414_03480	COG2378	regulation of single-species biofilm formation
KM414_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM414_03490	COG5002	protein histidine kinase activity
KM414_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM414_03520	COG0747	negative chemotaxis
KM414_03530	COG0601	transmembrane transport
KM414_03535	COG4608	Belongs to the ABC transporter superfamily
KM414_03545	COG2271	Major facilitator Superfamily
KM414_03550	COG1846	Transcriptional regulator
KM414_03560	COG1609	Transcriptional regulator
KM414_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM414_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM414_03585	COG1879	ABC-type sugar transport system periplasmic component
KM414_03610	COG1063	alcohol dehydrogenase
KM414_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM414_03650	COG1968	undecaprenyl-diphosphatase activity
KM414_03655	COG0840	transmembrane signaling receptor activity
KM414_03660	COG3584	3D domain protein
KM414_03660	COG1388	LysM domain
KM414_03665	COG1476	TRANSCRIPTIONal
KM414_03680	COG3104	oligopeptide transport
KM414_03685	COG1114	Component of the transport system for branched-chain amino acids
KM414_03700	COG1113	amino acid transport
KM414_03705	COG2252	PERMEase
KM414_03730	COG0475	glutathione-regulated potassium exporter activity
KM414_03730	COG0569	domain protein
KM414_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM414_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM414_03755	COG0833	amino acid
KM414_03760	COG4990	cell redox homeostasis
KM414_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM414_03780	COG0697	spore germination
KM414_03785	COG0531	amino acid
KM414_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM414_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM414_03805	COG1918	ferrous iron import across plasma membrane
KM414_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM414_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM414_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM414_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM414_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM414_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM414_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM414_03975	COG1116	anion transmembrane transporter activity
KM414_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM414_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM414_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM414_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM414_04000	COG2104	thiamine diphosphate biosynthetic process
KM414_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM414_04015	COG0351	phosphomethylpyrimidine kinase
KM414_04055	COG2205	protein histidine kinase activity
KM414_04060	COG2814	Major facilitator Superfamily
KM414_04065	COG1846	Transcriptional regulator
KM414_04080	COG2252	PERMEase
KM414_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM414_04105	COG1621	beta-fructofuranosidase activity
KM414_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_04110	COG1263	PTS System
KM414_04115	COG1609	Transcriptional regulator
KM414_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM414_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM414_04165	COG0778	Nitroreductase
KM414_04170	COG2719	SpoVR family
KM414_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM414_04200	COG1937	Protein conserved in bacteria
KM414_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM414_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM414_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM414_04235	COG0730	response to heat
KM414_04245	COG1316	TRANSCRIPTIONal
KM414_04250	COG0604	alcohol dehydrogenase
KM414_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM414_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM414_04270	COG3711	transcriptional antiterminator
KM414_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM414_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM414_04300	COG1388	LysM domain
KM414_04300	COG3584	3D domain protein
KM414_04305	COG0577	efflux transmembrane transporter activity
KM414_04310	COG1136	(ABC) transporter
KM414_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM414_04335	COG1114	Component of the transport system for branched-chain amino acids
KM414_04340	COG3546	catalase activity
KM414_04375	COG0586	Pfam SNARE associated Golgi protein
KM414_04410	COG0531	amino acid
KM414_04415	COG0475	glutathione-regulated potassium exporter activity
KM414_04425	COG1737	Transcriptional regulator
KM414_04435	COG1263	PTS System
KM414_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_04445	COG2259	Doxx family
KM414_04460	COG0697	spore germination
KM414_04465	COG1522	sequence-specific DNA binding
KM414_04480	COG2076	Multidrug Resistance protein
KM414_04485	COG1309	transcriptional regulator
KM414_04490	COG2814	Major facilitator Superfamily
KM414_04495	COG1733	regulation of RNA biosynthetic process
KM414_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM414_04510	COG4533	DNA binding
KM414_04515	COG2211	Major facilitator Superfamily
KM414_04525	COG0693	protein deglycase activity
KM414_04530	COG0693	protein deglycase activity
KM414_04530	COG0753	catalase activity
KM414_04540	COG0531	amino acid
KM414_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM414_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM414_04560	COG1132	(ABC) transporter
KM414_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM414_04575	COG0765	amino acid transport
KM414_04580	COG1126	abc transporter atp-binding protein
KM414_04595	COG0189	ligase activity
KM414_04625	COG0028	Belongs to the TPP enzyme family
KM414_04630	COG3527	Alpha-acetolactate decarboxylase
KM414_04645	COG0561	phosphatase activity
KM414_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM414_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM414_04695	COG0653	protein targeting
KM414_04700	COG2244	polysaccharide biosynthetic process
KM414_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM414_04715	COG4196	transglutaminase domain protein
KM414_04730	COG1696	Membrane protein involved in D-alanine export
KM414_04745	COG1024	Enoyl-CoA hydratase
KM414_04765	COG1363	Peptidase, m42
KM414_04785	COG3938	Belongs to the proline racemase family
KM414_04825	COG0601	transmembrane transport
KM414_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM414_04840	COG4608	Belongs to the ABC transporter superfamily
KM414_04845	COG0322	excinuclease ABC activity
KM414_04875	COG0477	Major facilitator Superfamily
KM414_04880	COG3290	protein histidine kinase activity
KM414_04885	COG4565	transcriptional regulatory protein
KM414_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM414_04920	COG0789	Transcriptional regulator
KM414_04920	COG4978	Transcriptional regulator
KM414_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM414_04975	COG0477	Major facilitator Superfamily
KM414_05020	COG3320	Male sterility
KM414_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM414_05025	COG1309	transcriptional regulator
KM414_05045	COG1183	phosphatidylcholine synthase activity
KM414_05065	COG2376	Dihydroxyacetone kinase
KM414_05075	COG2376	Dihydroxyacetone kinase
KM414_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM414_05085	COG1959	2 iron, 2 sulfur cluster binding
KM414_05115	COG3437	response regulator, receiver
KM414_05115	COG2770	Histidine kinase
KM414_05165	COG3237	CsbD-like
KM414_05190	COG1191	sigma factor activity
KM414_05200	COG2208	phosphoserine phosphatase activity
KM414_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM414_05210	COG2205	protein histidine kinase activity
KM414_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM414_05210	COG2198	Histidine kinase
KM414_05210	COG0784	Response regulator, receiver
KM414_05265	COG0420	3'-5' exonuclease activity
KM414_05270	COG4717	serine-type aminopeptidase activity
KM414_05290	COG1309	transcriptional regulator
KM414_05295	COG2814	Major facilitator Superfamily
KM414_05300	COG0346	lactoylglutathione lyase activity
KM414_05310	COG0346	lactoylglutathione lyase activity
KM414_05315	COG0457	Tetratricopeptide repeat
KM414_05320	COG2267	carboxylic ester hydrolase activity
KM414_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM414_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM414_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM414_05395	COG0477	Major facilitator Superfamily
KM414_05400	COG0477	Major facilitator Superfamily
KM414_05410	COG3973	AAA domain
KM414_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM414_05435	COG4980	gas vesicle protein
KM414_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM414_05445	COG1131	(ABC) transporter
KM414_05450	COG4473	ABC transporter
KM414_05465	COG1309	transcriptional regulator
KM414_05475	COG3402	PFAM membrane-flanked domain
KM414_05525	COG3402	PFAM membrane-flanked domain
KM414_05530	COG3428	Bacterial PH domain
KM414_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM414_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM414_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM414_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM414_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM414_05590	COG1309	transcriptional regulator
KM414_05595	COG1511	domain protein
KM414_05620	COG1609	Transcriptional regulator
KM414_05630	COG1234	tRNA 3'-trailer cleavage
KM414_05635	COG0095	Lipoate-protein ligase
KM414_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM414_05675	COG3209	COG3209 Rhs family protein
KM414_05715	COG1078	dGTPase activity
KM414_05725	COG1595	DNA-templated transcription, initiation
KM414_05730	COG3708	Transcriptional regulator
KM414_05730	COG2207	Transcriptional regulator
KM414_05745	COG2205	protein histidine kinase activity
KM414_05750	COG0745	RESPONSE REGULATOR receiver
KM414_05775	COG0501	Belongs to the peptidase M48B family
KM414_05780	COG0840	transmembrane signaling receptor activity
KM414_05785	COG0697	spore germination
KM414_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM414_05810	COG2224	Isocitrate lyase
KM414_05835	COG4903	ComK protein
KM414_05840	COG0398	Pfam SNARE associated Golgi protein
KM414_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM414_05855	COG1074	ATP-dependent DNA helicase activity
KM414_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM414_05925	COG0367	asparagine synthase
KM414_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM414_05935	COG0753	catalase activity
KM414_05940	COG0004	ammonium transporteR
KM414_05960	COG2996	Protein conserved in bacteria
KM414_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM414_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_05995	COG0561	phosphatase activity
KM414_06005	COG0542	response to heat
KM414_06015	COG2267	carboxylic ester hydrolase activity
KM414_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM414_06040	COG5504	Zn-dependent protease
KM414_06050	COG0180	Tryptophanyl-tRNA synthetase
KM414_06060	COG4166	transmembrane transport
KM414_06065	COG0601	transmembrane transport
KM414_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM414_06075	COG0444	Belongs to the ABC transporter superfamily
KM414_06080	COG4608	Belongs to the ABC transporter superfamily
KM414_06085	COG0534	Mate efflux family protein
KM414_06090	COG4166	transmembrane transport
KM414_06105	COG0861	Integral membrane protein TerC family
KM414_06110	COG4862	establishment of competence for transformation
KM414_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM414_06125	COG1164	Oligoendopeptidase f
KM414_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM414_06140	COG2346	COG2346, Truncated hemoglobins
KM414_06145	COG4116	CYTH
KM414_06155	COG2357	RelA SpoT domain protein
KM414_06165	COG0564	pseudouridine synthase activity
KM414_06185	COG1216	Glycosyl transferase, family 2
KM414_06185	COG0463	Glycosyl transferase, family 2
KM414_06205	COG0463	Glycosyl transferase, family 2
KM414_06205	COG0457	Tetratricopeptide repeat
KM414_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM414_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM414_06285	COG2153	protein acetylation
KM414_06295	COG2382	esterase
KM414_06310	COG5492	domain, Protein
KM414_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM414_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM414_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM414_06360	COG1620	l-lactate permease
KM414_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM414_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM414_06430	COG1476	TRANSCRIPTIONal
KM414_06490	COG2226	methyltransferase
KM414_06500	COG1686	Belongs to the peptidase S11 family
KM414_06505	COG0681	Belongs to the peptidase S26 family
KM414_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM414_06545	COG3842	ATPase activity
KM414_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM414_06555	COG1177	transmembrane transport
KM414_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM414_06570	COG2409	Drug exporters of the RND superfamily
KM414_06580	COG0564	pseudouridine synthase activity
KM414_06590	COG2340	Cysteine-rich secretory protein family
KM414_06595	COG0247	lactate metabolic process
KM414_06600	COG0277	FAD linked oxidase domain protein
KM414_06605	COG3835	regulator
KM414_06615	COG0745	RESPONSE REGULATOR receiver
KM414_06620	COG5002	protein histidine kinase activity
KM414_06625	COG2186	Transcriptional regulator
KM414_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM414_06660	COG2116	formate transmembrane transporter activity
KM414_06665	COG0861	Integral membrane protein TerC family
KM414_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM414_06680	COG2030	dehydratase
KM414_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM414_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM414_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM414_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM414_06760	COG1349	DNA-binding transcription factor activity
KM414_06780	COG2861	carbohydrate metabolic process
KM414_06790	COG3852	Histidine kinase
KM414_06795	COG1846	Transcriptional regulator
KM414_06805	COG2318	DinB family
KM414_06810	COG5002	protein histidine kinase activity
KM414_06820	COG0720	synthase
KM414_06835	COG4873	Protein conserved in bacteria
KM414_06865	COG1780	Probably involved in ribonucleotide reductase function
KM414_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM414_06890	COG1725	Transcriptional regulator
KM414_06895	COG1131	(ABC) transporter
KM414_06905	COG1131	(ABC) transporter
KM414_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM414_06925	COG1522	sequence-specific DNA binding
KM414_06935	COG1335	isochorismatase
KM414_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM414_06950	COG2070	2-Nitropropane dioxygenase
KM414_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM414_06965	COG1696	Membrane protein involved in D-alanine export
KM414_06985	COG0716	FMN binding
KM414_07000	COG3173	Aminoglycoside phosphotransferase
KM414_07020	COG0534	Mate efflux family protein
KM414_07025	COG1968	undecaprenyl-diphosphatase activity
KM414_07040	COG1846	Transcriptional regulator
KM414_07050	COG1301	dicarboxylic acid transport
KM414_07055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM414_07060	COG4709	membrane
KM414_07065	COG3874	Sporulation protein YtfJ
KM414_07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM414_07095	COG0028	Belongs to the TPP enzyme family
KM414_07100	COG0440	acetolactate synthase activity
KM414_07105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM414_07115	COG0473	3-isopropylmalate dehydrogenase activity
KM414_07140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM414_07175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM414_07190	COG1183	phosphatidylcholine synthase activity
KM414_07195	COG1368	sulfuric ester hydrolase activity
KM414_07205	COG0019	diaminopimelate decarboxylase activity
KM414_07225	COG0529	Catalyzes the synthesis of activated sulfate
KM414_07230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM414_07250	COG1648	precorrin-2 dehydrogenase activity
KM414_07255	COG0733	neurotransmitter:sodium symporter activity
KM414_07275	COG1757	Na H antiporter
KM414_07290	COG4758	membrane
KM414_07295	COG4585	Histidine kinase
KM414_07300	COG2197	response regulator
KM414_07310	COG1114	Component of the transport system for branched-chain amino acids
KM414_07320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM414_07345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM414_07345	COG1017	nitric oxide dioxygenase activity
KM414_07360	COG0730	response to heat
KM414_07365	COG0306	phosphate transporter
KM414_07370	COG1392	Phosphate transport regulator
KM414_07375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM414_07390	COG3852	Histidine kinase
KM414_07395	COG1801	Protein of unknown function DUF72
KM414_07405	COG0582	viral genome integration into host DNA
KM414_07410	COG5002	protein histidine kinase activity
KM414_07430	COG0392	lysyltransferase activity
KM414_07430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM414_07445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM414_07450	COG1686	Belongs to the peptidase S11 family
KM414_07455	COG2715	membrane protein required for spore maturation
KM414_07460	COG0700	Nucleoside recognition
KM414_07465	COG1187	pseudouridine synthase activity
KM414_07475	COG1333	cytochrome c biogenesis protein
KM414_07480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM414_07485	COG0745	RESPONSE REGULATOR receiver
KM414_07490	COG5002	protein histidine kinase activity
KM414_07495	COG2096	Adenosyltransferase
KM414_07510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM414_07515	COG1141	Ferredoxin
KM414_07520	COG4955	Helix-turn-helix domain
KM414_07525	COG0514	ATP-dependent DNA helicase (RecQ)
KM414_07530	COG1266	CAAX protease self-immunity
KM414_07550	COG4862	establishment of competence for transformation
KM414_07555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM414_07575	COG0492	ferredoxin-NADP+ reductase activity
KM414_07650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM414_07665	COG0142	geranyltranstransferase activity
KM414_07675	COG0142	geranyltranstransferase activity
KM414_07695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM414_07700	COG0457	Tetratricopeptide repeat
KM414_07720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM414_07730	COG4347	Protein of unknown function (DUF1405)
KM414_07745	COG2738	Putative neutral zinc metallopeptidase
KM414_07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_07760	COG1694	Mazg nucleotide pyrophosphohydrolase
KM414_07775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM414_07780	COG0438	transferase activity, transferring glycosyl groups
KM414_07815	COG1199	ATP-dependent helicase activity
KM414_07815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM414_07835	COG3935	DnaD domain protein
KM414_07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM414_07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM414_07850	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM414_07910	COG0116	Belongs to the methyltransferase superfamily
KM414_07920	COG1199	ATP-dependent helicase activity
KM414_07925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM414_07935	COG3173	Aminoglycoside phosphotransferase
KM414_07940	COG0024	Methionine aminopeptidase
KM414_07950	COG2233	PERMEase
KM414_07955	COG2311	Membrane
KM414_07960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM414_07970	COG0456	acetyltransferase
KM414_08020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM414_08045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM414_08060	COG1215	transferase activity, transferring glycosyl groups
KM414_08065	COG0438	transferase activity, transferring glycosyl groups
KM414_08080	COG0454	-acetyltransferase
KM414_08100	COG0328	RNA-DNA hybrid ribonuclease activity
KM414_08140	COG1280	lysine exporter protein (LysE YggA)
KM414_08155	COG3162	membrane
KM414_08160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM414_08165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM414_08175	COG0475	glutathione-regulated potassium exporter activity
KM414_08180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM414_08185	COG4978	Transcriptional regulator
KM414_08185	COG0789	Transcriptional regulator
KM414_08195	COG2323	membrane
KM414_08200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM414_08255	COG1923	regulation of RNA biosynthetic process
KM414_08265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM414_08270	COG1360	Flagellar Motor Protein
KM414_08275	COG2201	protein-glutamate methylesterase activity
KM414_08280	COG0643	Histidine kinase
KM414_08280	COG2198	Histidine kinase
KM414_08285	COG0643	Histidine kinase
KM414_08285	COG2198	Histidine kinase
KM414_08290	COG1776	CheC inhibitor of MCP methylation
KM414_08290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM414_08305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM414_08325	COG1256	bacterial-type flagellum assembly
KM414_08350	COG1815	bacterial-type flagellum-dependent cell motility
KM414_08355	COG1558	bacterial-type flagellum-dependent cell motility
KM414_08370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM414_08380	COG1157	protein secretion by the type III secretion system
KM414_08420	COG0784	Response regulator, receiver
KM414_08420	COG0835	chemotaxis
KM414_08430	COG0463	Glycosyl transferase, family 2
KM414_08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM414_08470	COG0741	lytic transglycosylase activity
KM414_08485	COG1776	CheC inhibitor of MCP methylation
KM414_08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM414_08495	COG1338	Plays a role in the flagellum-specific transport system
KM414_08500	COG1987	bacterial-type flagellum assembly
KM414_08510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM414_08515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM414_08520	COG1419	protein localization to endoplasmic reticulum
KM414_08525	COG4786	Flagellar basal body rod
KM414_08530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM414_08555	COG1309	transcriptional regulator
KM414_08575	COG2329	Antibiotic biosynthesis monooxygenase
KM414_08600	COG0583	DNA-binding transcription factor activity
KM414_08605	COG3842	ATPase activity
KM414_08610	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM414_08620	COG1234	tRNA 3'-trailer cleavage
KM414_08645	COG1686	Belongs to the peptidase S11 family
KM414_08655	COG0406	alpha-ribazole phosphatase activity
KM414_08685	COG0367	asparagine synthase
KM414_08715	COG1802	Transcriptional regulator
KM414_08720	COG0697	spore germination
KM414_08725	COG0523	cobalamin synthesis protein
KM414_08730	COG0701	Predicted permease
KM414_08740	COG0438	transferase activity, transferring glycosyl groups
KM414_08740	COG1216	Glycosyl transferase, family 2
KM414_08745	COG1757	Na H antiporter
KM414_08750	COG0114	fumarate hydratase activity
KM414_08775	COG3340	Belongs to the peptidase S51 family
KM414_08795	COG0785	Cytochrome C biogenesis protein
KM414_08825	COG2733	membrane
KM414_08860	COG1131	(ABC) transporter
KM414_08875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM414_08880	COG0528	UMP kinase activity
KM414_08890	COG1027	Aspartate ammonia-lyase
KM414_08895	COG0281	malic enzyme
KM414_08900	COG4191	Histidine kinase
KM414_08905	COG0784	Response regulator, receiver
KM414_08910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM414_08965	COG1051	belongs to the nudix hydrolase family
KM414_08970	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM414_08980	COG2814	Major facilitator Superfamily
KM414_08995	COG1966	Carbon starvation protein
KM414_09010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_09020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM414_09030	COG2223	nitrite transmembrane transporter activity
KM414_09035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM414_09050	COG2244	polysaccharide biosynthetic process
KM414_09055	COG0733	neurotransmitter:sodium symporter activity
KM414_09065	COG5566	PFAM Mor transcription activator
KM414_09070	COG2323	membrane
KM414_09085	COG2084	Dehydrogenase
KM414_09100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM414_09110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM414_09115	COG0028	Belongs to the TPP enzyme family
KM414_09120	COG0440	acetolactate synthase activity
KM414_09125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM414_09135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM414_09160	COG2814	Major facilitator Superfamily
KM414_09165	COG3384	dioxygenase
KM414_09175	COG3279	Response regulator of the LytR AlgR family
KM414_09180	COG0427	acetyl-CoA hydrolase
KM414_09200	COG1073	alpha beta
KM414_09230	COG0535	radical SAM domain protein
KM414_09235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_09255	COG1914	H( )-stimulated, divalent metal cation uptake system
KM414_09270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM414_09300	COG2390	Transcriptional regulator
KM414_09310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_09315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM414_09330	COG4224	UPF0291 protein
KM414_09350	COG0006	proline dipeptidase activity
KM414_09355	COG2132	Multicopper oxidase
KM414_09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM414_09385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM414_09400	COG1276	copper resistance
KM414_09400	COG2372	response to copper ion
KM414_09405	COG4549	nuclear export factor GLE1
KM414_09415	COG0697	spore germination
KM414_09420	COG0583	DNA-binding transcription factor activity
KM414_09425	COG1959	2 iron, 2 sulfur cluster binding
KM414_09430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM414_09435	COG0778	Nitroreductase
KM414_09445	COG0628	permease
KM414_09455	COG1231	oxidoreductase activity
KM414_09460	COG0523	cobalamin synthesis protein
KM414_09480	COG2030	dehydratase
KM414_09485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_09495	COG0411	ABC transporter
KM414_09515	COG0583	DNA-binding transcription factor activity
KM414_09525	COG1942	4-Oxalocrotonate Tautomerase
KM414_09535	COG1846	Transcriptional regulator
KM414_09545	COG1271	oxidase subunit
KM414_09550	COG1294	oxidase, subunit
KM414_09555	COG4988	ABC transporter
KM414_09560	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM414_09580	COG1686	Belongs to the peptidase S11 family
KM414_09595	COG1388	LysM domain
KM414_09595	COG0791	NLP P60 protein
KM414_09610	COG0745	RESPONSE REGULATOR receiver
KM414_09615	COG5002	protein histidine kinase activity
KM414_09625	COG0300	oxidoreductase activity
KM414_09660	COG0460	homoserine dehydrogenase
KM414_09685	COG1316	TRANSCRIPTIONal
KM414_09695	COG0745	RESPONSE REGULATOR receiver
KM414_09700	COG5002	protein histidine kinase activity
KM414_09715	COG1285	pathogenesis
KM414_09720	COG1247	-acetyltransferase
KM414_09740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM414_09750	COG1082	Xylose isomerase domain protein TIM barrel
KM414_09765	COG1279	arginine transmembrane transporter activity
KM414_09775	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM414_09815	COG2002	toxin-antitoxin pair type II binding
KM414_09820	COG1404	Belongs to the peptidase S8 family
KM414_09825	COG0640	Transcriptional regulator
KM414_09830	COG0667	Aldo Keto reductase
KM414_09835	COG2814	Major facilitator Superfamily
KM414_09860	COG0840	transmembrane signaling receptor activity
KM414_09875	COG3949	Membrane
KM414_09880	COG0783	Belongs to the Dps family
KM414_09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM414_09905	COG1231	oxidoreductase activity
KM414_09915	COG4989	oxidoreductase activity
KM414_09920	COG0523	cobalamin synthesis protein
KM414_09925	COG0456	acetyltransferase
KM414_09980	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM414_09980	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM414_09990	COG0702	epimerase
KM414_10000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM414_10010	COG4166	transmembrane transport
KM414_10025	COG0406	alpha-ribazole phosphatase activity
KM414_10035	COG5337	Spore coat protein CotH
KM414_10040	COG1051	belongs to the nudix hydrolase family
KM414_10045	COG0586	Pfam SNARE associated Golgi protein
KM414_10050	COG2244	polysaccharide biosynthetic process
KM414_10060	COG0701	Predicted permease
KM414_10065	COG3689	TIGRFAM TIGR03943 family protein
KM414_10070	COG1607	acyl-coa hydrolase
KM414_10080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM414_10095	COG0702	epimerase
KM414_10100	COG2839	Protein conserved in bacteria
KM414_10105	COG1253	flavin adenine dinucleotide binding
KM414_10120	COG1114	Component of the transport system for branched-chain amino acids
KM414_10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM414_10145	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM414_10155	COG1876	peptidase activity
KM414_10165	COG0154	amidase activity
KM414_10170	COG2211	Major facilitator Superfamily
KM414_10190	COG0561	phosphatase activity
KM414_10200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM414_10205	COG4106	trans-aconitate 2-methyltransferase activity
KM414_10220	COG1819	glycosyl
KM414_10225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_10230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_10255	COG0456	acetyltransferase
KM414_10305	COG3874	Sporulation protein YtfJ
KM414_10330	COG2226	methyltransferase
KM414_10355	COG0346	lactoylglutathione lyase activity
KM414_10365	COG0604	alcohol dehydrogenase
KM414_10370	COG1595	DNA-templated transcription, initiation
KM414_10395	COG0386	Belongs to the glutathione peroxidase family
KM414_10400	COG1305	Transglutaminase-like
KM414_10405	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM414_10410	COG0714	Associated with various cellular activities
KM414_10425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM414_10430	COG1140	nitrate reductase beta subunit
KM414_10435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM414_10440	COG2181	nitrate reductase activity
KM414_10460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM414_10465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM414_10470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM414_10475	COG0303	'Molybdopterin
KM414_10480	COG0314	molybdopterin synthase activity
KM414_10490	COG2223	nitrite transmembrane transporter activity
KM414_10505	COG1648	precorrin-2 dehydrogenase activity
KM414_10515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM414_10515	COG1587	Uroporphyrinogen-III synthase
KM414_10520	COG2146	nitrite reductase [NAD(P)H] activity
KM414_10525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM414_10530	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM414_10565	COG2359	stage V sporulation protein S
KM414_10580	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM414_10595	COG1418	mRNA catabolic process
KM414_10600	COG0488	(ABC) transporter
KM414_10615	COG0629	single-stranded DNA binding
KM414_10630	COG1413	lyase activity
KM414_10645	COG2521	methyltransferase
KM414_10645	COG2136	Putative SAM-dependent methyltransferase
KM414_10650	COG0018	arginyl-trna synthetase
KM414_10675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM414_10695	COG0017	Asparaginyl-tRNA synthetase
KM414_10715	COG1674	ftsk spoiiie
KM414_10785	COG1929	Belongs to the glycerate kinase type-1 family
KM414_10790	COG0471	metal ion transport
KM414_10795	COG0745	RESPONSE REGULATOR receiver
KM414_10800	COG3850	Histidine kinase
KM414_10800	COG5002	protein histidine kinase activity
KM414_10815	COG0733	neurotransmitter:sodium symporter activity
KM414_10840	COG2610	gluconate transmembrane transporter activity
KM414_10845	COG1454	alcohol dehydrogenase
KM414_10850	COG1794	racemase activity, acting on amino acids and derivatives
KM414_10860	COG0456	acetyltransferase
KM414_10875	COG1131	(ABC) transporter
KM414_10890	COG0546	phosphoglycolate phosphatase activity
KM414_10910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM414_10925	COG0768	penicillin binding
KM414_10930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM414_10935	COG0204	Acyl-transferase
KM414_10940	COG1272	protein, Hemolysin III
KM414_10950	COG0805	protein transport
KM414_10960	COG1307	EDD domain protein, DegV family
KM414_10965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM414_10970	COG1999	signal sequence binding
KM414_10975	COG0071	Belongs to the small heat shock protein (HSP20) family
KM414_10980	COG0367	asparagine synthase
KM414_10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM414_11025	COG1051	belongs to the nudix hydrolase family
KM414_11035	COG0668	transmembrane transport
KM414_11040	COG4585	Histidine kinase
KM414_11040	COG2203	Gaf domain
KM414_11045	COG2197	response regulator
KM414_11055	COG1064	alcohol dehydrogenase
KM414_11080	COG1070	Carbohydrate kinase
KM414_11085	COG1070	Carbohydrate kinase
KM414_11115	COG0517	IMP dehydrogenase activity
KM414_11115	COG1125	glycine betaine transport
KM414_11120	COG1174	glycine betaine transport
KM414_11155	COG1253	flavin adenine dinucleotide binding
KM414_11160	COG1012	belongs to the aldehyde dehydrogenase family
KM414_11165	COG5506	Protein of unknown function (DUF1694)
KM414_11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM414_11185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM414_11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM414_11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM414_11200	COG0456	acetyltransferase
KM414_11205	COG3829	transcription factor binding
KM414_11210	COG1509	lysine 2,3-aminomutase activity
KM414_11250	COG4326	sporulation control protein
KM414_11255	COG0671	phosphoesterase, PA-phosphatase related
KM414_11260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM414_11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM414_11295	COG1787	Restriction endonuclease
KM414_11295	COG1715	Restriction endonuclease
KM414_11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM414_11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM414_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM414_11430	COG2814	Major facilitator Superfamily
KM414_11435	COG4841	protein insertion into membrane
KM414_11440	COG0372	Belongs to the citrate synthase family
KM414_11445	COG2079	MmgE PrpD family protein
KM414_11450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM414_11455	COG1960	acyl-CoA dehydrogenase activity
KM414_11460	COG2084	Dehydrogenase
KM414_11470	COG1280	lysine exporter protein (LysE YggA)
KM414_11475	COG1024	Enoyl-CoA hydratase
KM414_11490	COG0420	3'-5' exonuclease activity
KM414_11495	COG0419	ATPase involved in DNA repair
KM414_11520	COG2223	nitrite transmembrane transporter activity
KM414_11525	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_11530	COG1169	isochorismate synthase
KM414_11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM414_11540	COG3433	isochorismatase activity
KM414_11540	COG1535	isochorismatase
KM414_11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM414_11550	COG3251	PFAM MbtH domain protein
KM414_11555	COG2814	Major facilitator Superfamily
KM414_11570	COG0776	regulation of translation
KM414_11580	COG2318	DinB family
KM414_11590	COG1115	amino acid carrier protein
KM414_11605	COG2329	Antibiotic biosynthesis monooxygenase
KM414_11610	COG1187	pseudouridine synthase activity
KM414_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM414_11630	COG0596	Alpha beta hydrolase
KM414_11635	COG2814	Major facilitator Superfamily
KM414_11655	COG2226	methyltransferase
KM414_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_11735	COG1247	-acetyltransferase
KM414_11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM414_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_11785	COG1278	Cold shock
KM414_11800	COG0010	Belongs to the arginase family
KM414_11805	COG0561	phosphatase activity
KM414_11850	COG0583	DNA-binding transcription factor activity
KM414_11855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM414_11870	COG0583	DNA-binding transcription factor activity
KM414_11875	COG2258	MOSC domain
KM414_11890	COG1132	(ABC) transporter
KM414_11895	COG1132	(ABC) transporter
KM414_11915	COG1396	sequence-specific DNA binding
KM414_11940	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM414_11945	COG1595	DNA-templated transcription, initiation
KM414_11970	COG1649	PFAM Uncharacterised BCR, COG1649
KM414_11995	COG2971	BadF BadG BcrA BcrD
KM414_12000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM414_12005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM414_12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_12055	COG1309	transcriptional regulator
KM414_12070	COG1136	(ABC) transporter
KM414_12070	COG0577	efflux transmembrane transporter activity
KM414_12075	COG0500	methyltransferase
KM414_12075	COG3615	Tellurite resistance protein tehB
KM414_12085	COG2226	methyltransferase
KM414_12090	COG3961	Belongs to the TPP enzyme family
KM414_12095	COG1846	Transcriptional regulator
KM414_12135	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM414_12150	COG1595	DNA-templated transcription, initiation
KM414_12160	COG0768	penicillin binding
KM414_12170	COG2367	Beta-lactamase
KM414_12175	COG0671	phosphoesterase, PA-phosphatase related
KM414_12180	COG1609	Transcriptional regulator
KM414_12185	COG2814	Major facilitator Superfamily
KM414_12190	COG0673	inositol 2-dehydrogenase activity
KM414_12200	COG1012	belongs to the aldehyde dehydrogenase family
KM414_12215	COG0191	fructose-bisphosphate aldolase activity
KM414_12220	COG3718	enzyme involved in inositol metabolism
KM414_12245	COG0457	Tetratricopeptide repeat
KM414_12250	COG1476	TRANSCRIPTIONal
KM414_12265	COG1876	peptidase activity
KM414_12285	COG1309	transcriptional regulator
KM414_12290	COG0488	(ABC) transporter
KM414_12305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_12320	COG1252	NADH dehydrogenase
KM414_12325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_12340	COG1131	(ABC) transporter
KM414_12350	COG1309	transcriptional regulator
KM414_12365	COG1960	acyl-CoA dehydrogenase activity
KM414_12370	COG0439	Biotin carboxylase
KM414_12375	COG0511	ligase activity, forming carbon-carbon bonds
KM414_12380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM414_12385	COG1024	Enoyl-CoA hydratase
KM414_12390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM414_12395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM414_12405	COG1247	-acetyltransferase
KM414_12410	COG0572	uridine kinase
KM414_12420	COG2318	DinB family
KM414_12425	COG1686	Belongs to the peptidase S11 family
KM414_12450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM414_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM414_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM414_12515	COG2814	Major facilitator Superfamily
KM414_12535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM414_12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_12570	COG1063	alcohol dehydrogenase
KM414_12600	COG3773	Cell wall hydrolase
KM414_12610	COG0745	RESPONSE REGULATOR receiver
KM414_12625	COG0488	(ABC) transporter
KM414_12640	COG1136	(ABC) transporter
KM414_12665	COG0460	homoserine dehydrogenase
KM414_12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_12680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM414_12745	COG2124	cytochrome p450
KM414_12780	COG0561	phosphatase activity
KM414_12790	COG5002	protein histidine kinase activity
KM414_12795	COG0768	penicillin binding
KM414_12800	COG1819	glycosyl
KM414_12805	COG1794	racemase activity, acting on amino acids and derivatives
KM414_12815	COG1122	ATPase activity
KM414_12830	COG2205	protein histidine kinase activity
KM414_12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM414_12845	COG0604	alcohol dehydrogenase
KM414_12850	COG0768	penicillin binding
KM414_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM414_12895	COG0693	protein deglycase activity
KM414_12925	COG2814	Major facilitator Superfamily
KM414_12940	COG0584	glycerophosphoryl diester phosphodiesterase
KM414_12960	COG0697	spore germination
KM414_12985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM414_12995	COG2223	nitrite transmembrane transporter activity
KM414_13010	COG2816	NAD+ diphosphatase activity
KM414_13015	COG0592	DNA-directed DNA polymerase activity
KM414_13020	COG1051	belongs to the nudix hydrolase family
KM414_13055	COG3878	Protein conserved in bacteria
KM414_13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM414_13115	COG0322	excinuclease ABC activity
KM414_13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM414_13185	COG1011	Hydrolase
KM414_13205	COG0076	glutamate decarboxylase activity
KM414_13220	COG1523	belongs to the glycosyl hydrolase 13 family
KM414_13225	COG3227	Zinc metalloprotease (Elastase)
KM414_13245	COG0201	protein transport
KM414_13255	COG0697	spore germination
KM414_13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_13290	COG4129	membrane
KM414_13295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_13310	COG2959	enzyme of heme biosynthesis
KM414_13330	COG3483	tryptophan 2,3-dioxygenase activity
KM414_13335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM414_13340	COG3844	kynureninase activity
KM414_13345	COG1309	transcriptional regulator
KM414_13375	COG3284	Transcriptional regulator
KM414_13395	COG1349	DNA-binding transcription factor activity
KM414_13415	COG1959	2 iron, 2 sulfur cluster binding
KM414_13430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM414_13435	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM414_13440	COG0022	dehydrogenase e1 component
KM414_13445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM414_13455	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_13460	COG0456	acetyltransferase
KM414_13460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM414_13490	COG4176	ABC-type proline glycine betaine transport system permease component
KM414_13495	COG0517	IMP dehydrogenase activity
KM414_13495	COG4175	Glycine betaine
KM414_13520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM414_13525	COG2153	protein acetylation
KM414_13530	COG3397	chitin binding
KM414_13545	COG2205	protein histidine kinase activity
KM414_13570	COG0658	competence protein
KM414_13570	COG2333	competence protein COMEC
KM414_13620	COG3973	AAA domain
KM414_13635	COG2105	PFAM AIG2 family protein
KM414_13640	COG0514	ATP-dependent DNA helicase (RecQ)
KM414_13660	COG4637	Psort location Cytoplasmic, score
KM414_13685	COG3397	chitin binding
KM414_13700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM414_13705	COG1115	amino acid carrier protein
KM414_13710	COG1012	belongs to the aldehyde dehydrogenase family
KM414_13715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM414_13725	COG3938	Belongs to the proline racemase family
KM414_13730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM414_13770	COG0586	Pfam SNARE associated Golgi protein
KM414_13785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM414_13790	COG0519	Catalyzes the synthesis of GMP from XMP
KM414_13795	COG4166	transmembrane transport
KM414_13805	COG4948	Mandelate Racemase Muconate Lactonizing
KM414_13850	COG2936	dipeptidyl-peptidase activity
KM414_13855	COG5002	protein histidine kinase activity
KM414_13895	COG1164	Oligoendopeptidase f
KM414_13910	COG1307	EDD domain protein, DegV family
KM414_13930	COG2814	Major facilitator Superfamily
KM414_13940	COG1664	Polymer-forming cytoskeletal
KM414_13945	COG0789	Transcriptional regulator
KM414_13950	COG4533	DNA binding
KM414_13955	COG2814	Major facilitator Superfamily
KM414_13955	COG0477	Major facilitator Superfamily
KM414_13975	COG2261	transglycosylase associated protein
KM414_13990	COG2226	methyltransferase
KM414_14025	COG0436	Aminotransferase
KM414_14030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM414_14035	COG5146	pantothenate kinase activity
KM414_14055	COG1131	(ABC) transporter
KM414_14100	COG0628	permease
KM414_14110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM414_14115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM414_14120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM414_14125	COG1116	anion transmembrane transporter activity
KM414_14145	COG2816	NAD+ diphosphatase activity
KM414_14165	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM414_14190	COG0697	spore germination
KM414_14195	COG2318	DinB family
KM414_14215	COG4912	Dna alkylation repair
KM414_14235	COG0861	Integral membrane protein TerC family
KM414_14240	COG1368	sulfuric ester hydrolase activity
KM414_14245	COG0488	(ABC) transporter
KM414_14255	COG2409	Drug exporters of the RND superfamily
KM414_14255	COG1033	growth of symbiont in host cell
KM414_14260	COG1033	growth of symbiont in host cell
KM414_14260	COG2409	Drug exporters of the RND superfamily
KM414_14265	COG1033	growth of symbiont in host cell
KM414_14265	COG2409	Drug exporters of the RND superfamily
KM414_14270	COG1309	transcriptional regulator
KM414_14285	COG0287	Prephenate dehydrogenase
KM414_14290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM414_14295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM414_14300	COG1605	Chorismate mutase
KM414_14300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM414_14335	COG3584	3D domain protein
KM414_14335	COG1388	LysM domain
KM414_14345	COG1595	DNA-templated transcription, initiation
KM414_14370	COG1879	ABC-type sugar transport system periplasmic component
KM414_14380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM414_14390	COG2390	Transcriptional regulator
KM414_14425	COG2329	Antibiotic biosynthesis monooxygenase
KM414_14445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_14455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM414_14460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM414_14465	COG4187	Peptidase family M20/M25/M40
KM414_14470	COG1414	Transcriptional regulator
KM414_14475	COG0833	amino acid
KM414_14480	COG1690	Belongs to the RtcB family
KM414_14485	COG3239	Fatty acid desaturase
KM414_14490	COG1785	Belongs to the alkaline phosphatase family
KM414_14500	COG3655	Transcriptional regulator
KM414_14515	COG4377	Putative membrane peptidase family (DUF2324)
KM414_14525	COG3279	Response regulator of the LytR AlgR family
KM414_14535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_14540	COG0346	lactoylglutathione lyase activity
KM414_14560	COG0714	Associated with various cellular activities
KM414_14585	COG0463	Glycosyl transferase, family 2
KM414_14610	COG0463	Glycosyl transferase, family 2
KM414_14620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM414_14625	COG0753	catalase activity
KM414_14635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM414_14660	COG0714	Associated with various cellular activities
KM414_14670	COG0778	Nitroreductase
KM414_14675	COG1846	Transcriptional regulator
KM414_14710	COG1725	Transcriptional regulator
KM414_14720	COG0577	efflux transmembrane transporter activity
KM414_14720	COG1136	(ABC) transporter
KM414_14745	COG2207	Transcriptional regulator
KM414_14750	COG0456	acetyltransferase
KM414_14770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_14790	COG0642	Histidine kinase
KM414_14795	COG0745	RESPONSE REGULATOR receiver
KM414_14800	COG0596	Alpha beta hydrolase
KM414_14830	COG0730	response to heat
KM414_14840	COG0833	amino acid
KM414_14850	COG4335	DNA alkylation repair
KM414_14890	COG0768	penicillin binding
KM414_14900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM414_14930	COG1984	allophanate hydrolase subunit 2
KM414_14935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM414_14940	COG1414	Transcriptional regulator
KM414_14955	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM414_14960	COG0640	Transcriptional regulator
KM414_14970	COG1960	acyl-CoA dehydrogenase activity
KM414_14985	COG3314	Sporulation integral membrane protein YlbJ
KM414_15000	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM414_15015	COG0574	Belongs to the PEP-utilizing enzyme family
KM414_15015	COG3848	Pyruvate phosphate dikinase
KM414_15020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_15035	COG5577	PFAM Coat F domain
KM414_15040	COG3403	YqcI/YcgG family
KM414_15045	COG1280	lysine exporter protein (LysE YggA)
KM414_15080	COG1063	alcohol dehydrogenase
KM414_15095	COG1027	Aspartate ammonia-lyase
KM414_15100	COG0252	asparaginase activity
KM414_15105	COG1396	sequence-specific DNA binding
KM414_15115	COG0322	excinuclease ABC activity
KM414_15120	COG0531	amino acid
KM414_15125	COG1114	Component of the transport system for branched-chain amino acids
KM414_15130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM414_15140	COG0281	malic enzyme
KM414_15155	COG0531	amino acid
KM414_15165	COG0784	Response regulator, receiver
KM414_15175	COG2066	Belongs to the glutaminase family
KM414_15180	COG1115	amino acid carrier protein
KM414_15210	COG0737	Belongs to the 5'-nucleotidase family
KM414_15215	COG0753	catalase activity
KM414_15220	COG2267	carboxylic ester hydrolase activity
KM414_15225	COG1335	isochorismatase
KM414_15245	COG0583	DNA-binding transcription factor activity
KM414_15250	COG1846	Transcriptional regulator
KM414_15290	COG0415	Belongs to the DNA photolyase family
KM414_15295	COG0288	reversible hydration of carbon dioxide
KM414_15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM414_15310	COG5609	conserved protein (DUF2294)
KM414_15325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM414_15330	COG2267	carboxylic ester hydrolase activity
KM414_15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM414_15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM414_15345	COG1121	(ABC) transporter
KM414_15375	COG0798	PFAM Bile acid sodium symporter
KM414_15380	COG0346	lactoylglutathione lyase activity
KM414_15385	COG0640	Transcriptional regulator
KM414_15400	COG0443	Heat shock 70 kDa protein
KM414_15415	COG1522	sequence-specific DNA binding
KM414_15430	COG0346	lactoylglutathione lyase activity
KM414_15455	COG2169	Transcriptional regulator
KM414_15500	COG2814	Major facilitator Superfamily
KM414_15525	COG0745	RESPONSE REGULATOR receiver
KM414_15530	COG3850	Histidine kinase
KM414_15530	COG5002	protein histidine kinase activity
KM414_15555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM414_15575	COG1476	TRANSCRIPTIONal
KM414_15590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_15595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM414_15605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_15610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM414_15625	COG1136	(ABC) transporter
KM414_15630	COG0577	efflux transmembrane transporter activity
KM414_15645	COG3850	Histidine kinase
KM414_15645	COG5002	protein histidine kinase activity
KM414_15655	COG2364	Membrane
KM414_15660	COG1846	Transcriptional regulator
KM414_15670	COG2808	Putative FMN-binding domain
KM414_15675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_15680	COG2271	Major facilitator Superfamily
KM414_15685	COG1556	Lactate utilization protein
KM414_15690	COG1139	Iron-sulfur cluster binding protein
KM414_15700	COG0583	DNA-binding transcription factor activity
KM414_15710	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM414_15735	COG0738	Major facilitator superfamily
KM414_15740	COG0673	inositol 2-dehydrogenase activity
KM414_15745	COG0561	phosphatase activity
KM414_15755	COG1609	Transcriptional regulator
KM414_15760	COG0457	Tetratricopeptide repeat
KM414_15780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM414_15810	COG0534	Mate efflux family protein
KM414_15830	COG2814	Major facilitator Superfamily
KM414_15835	COG1309	transcriptional regulator
KM414_15850	COG0814	amino acid
KM414_15855	COG1760	l-serine dehydratase
KM414_15860	COG1760	l-serine dehydratase
KM414_15870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM414_15875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM414_15885	COG1335	isochorismatase
KM414_15890	COG1522	sequence-specific DNA binding
KM414_15895	COG0531	amino acid
KM414_15910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM414_15930	COG1595	DNA-templated transcription, initiation
KM414_15945	COG0662	Cupin 2, conserved barrel domain protein
KM414_15950	COG2207	Transcriptional regulator
KM414_15950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_16000	COG0477	Major facilitator Superfamily
KM414_16010	COG1846	Transcriptional regulator
KM414_16015	COG2814	Major facilitator Superfamily
KM414_16025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM414_16030	COG1131	(ABC) transporter
KM414_16050	COG2076	Multidrug Resistance protein
KM414_16055	COG1309	transcriptional regulator
KM414_16065	COG2031	fatty acid transporter
KM414_16075	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM414_16105	COG1122	ATPase activity
KM414_16110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM414_16125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM414_16130	COG1288	antiporter activity
KM414_16135	COG2356	endonuclease I
KM414_16150	COG3620	sequence-specific DNA binding
KM414_16155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM414_16160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM414_16165	COG0124	histidyl-tRNA synthetase
KM414_16180	COG1733	regulation of RNA biosynthetic process
KM414_16185	COG0778	Nitroreductase
KM414_16205	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_16215	COG1131	(ABC) transporter
KM414_16240	COG1011	Hydrolase
KM414_16250	COG2365	Tyrosine phosphatase family
KM414_16275	COG0346	lactoylglutathione lyase activity
KM414_16280	COG1940	carbohydrate kinase activity
KM414_16285	COG0738	Major facilitator superfamily
KM414_16290	COG0110	maltose O-acetyltransferase activity
KM414_16300	COG0577	efflux transmembrane transporter activity
KM414_16300	COG1136	(ABC) transporter
KM414_16315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM414_16320	COG0628	permease
KM414_16340	COG2226	methyltransferase
KM414_16350	COG0477	Major facilitator Superfamily
KM414_16380	COG1253	flavin adenine dinucleotide binding
KM414_16385	COG0789	Transcriptional regulator
KM414_16390	COG0697	spore germination
KM414_16395	COG1357	PFAM Pentapeptide repeats (8 copies)
KM414_16400	COG3813	Protein conserved in bacteria
KM414_16405	COG2706	6-phosphogluconolactonase activity
KM414_16410	COG1070	Carbohydrate kinase
KM414_16420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM414_16425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM414_16435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM414_16440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM414_16445	COG0604	alcohol dehydrogenase
KM414_16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM414_16460	COG3321	synthase
KM414_16460	COG0604	alcohol dehydrogenase
KM414_16465	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_16490	COG0656	L-ascorbic acid biosynthetic process
KM414_16495	COG2814	Major facilitator Superfamily
KM414_16510	COG0346	lactoylglutathione lyase activity
KM414_16515	COG0814	amino acid
KM414_16540	COG1393	Belongs to the ArsC family
KM414_16545	COG1733	regulation of RNA biosynthetic process
KM414_16550	COG2188	Transcriptional regulator
KM414_16560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM414_16565	COG1733	regulation of RNA biosynthetic process
KM414_16570	COG1733	regulation of RNA biosynthetic process
KM414_16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_16605	COG0384	phenazine biosynthesis protein PhzF
KM414_16615	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_16625	COG0318	PFAM AMP-dependent synthetase and ligase
KM414_16635	COG1733	regulation of RNA biosynthetic process
KM414_16670	COG1191	sigma factor activity
KM414_16685	COG1309	transcriptional regulator
KM414_16705	COG3152	Membrane
KM414_16730	COG1151	hydroxylamine reductase activity
KM414_16740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_16745	COG3409	Peptidoglycan-binding domain 1 protein
KM414_16745	COG3757	hydrolase, family 25
KM414_16780	COG2072	flavoprotein involved in K transport
KM414_16815	COG0604	alcohol dehydrogenase
KM414_16820	COG1113	amino acid transport
KM414_16825	COG2814	Major facilitator Superfamily
KM414_16855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM414_16860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM414_16880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_16890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_16895	COG3739	integral membrane protein
KM414_16900	COG0384	phenazine biosynthesis protein PhzF
KM414_16930	COG0583	DNA-binding transcription factor activity
KM414_16950	COG1193	negative regulation of DNA recombination
KM414_16975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM414_17005	COG0584	glycerophosphoryl diester phosphodiesterase
KM414_17030	COG0640	Transcriptional regulator
KM414_17035	COG0604	alcohol dehydrogenase
KM414_17055	COG2808	Putative FMN-binding domain
KM414_17060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM414_17070	COG0385	Bile acid
KM414_17075	COG0277	FAD linked oxidase domain protein
KM414_17105	COG1216	Glycosyl transferase, family 2
KM414_17110	COG1024	Enoyl-CoA hydratase
KM414_17120	COG1285	pathogenesis
KM414_17135	COG2514	catechol 2,3-dioxygenase activity
KM414_17140	COG2720	vancomycin resistance protein
KM414_17180	COG0716	FMN binding
KM414_17210	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_17220	COG0165	Argininosuccinate lyase
KM414_17235	COG4145	pantothenate transmembrane transporter activity
KM414_17245	COG1012	belongs to the aldehyde dehydrogenase family
KM414_17250	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_17260	COG1657	PFAM Prenyltransferase squalene oxidase
KM414_17265	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM414_17270	COG2962	Rard protein
KM414_17275	COG3326	Membrane
KM414_17290	COG0489	protein tyrosine kinase activity
KM414_17300	COG0314	molybdopterin synthase activity
KM414_17305	COG0303	'Molybdopterin
KM414_17310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM414_17315	COG2116	formate transmembrane transporter activity
KM414_17325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM414_17330	COG5609	conserved protein (DUF2294)
KM414_17335	COG2427	Protein of unknown function (DUF1641)
KM414_17340	COG3383	formate dehydrogenase (NAD+) activity
KM414_17345	COG0697	spore germination
KM414_17385	COG2226	methyltransferase
KM414_17390	COG4166	transmembrane transport
KM414_17395	COG4166	transmembrane transport
KM414_17400	COG4166	transmembrane transport
KM414_17405	COG1301	dicarboxylic acid transport
KM414_17410	COG1316	TRANSCRIPTIONal
KM414_17420	COG1595	DNA-templated transcription, initiation
KM414_17440	COG1131	(ABC) transporter
KM414_17450	COG0673	inositol 2-dehydrogenase activity
KM414_17455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM414_17460	COG0187	DNA topoisomerase II activity
KM414_17465	COG1832	CoA-binding protein
KM414_17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM414_17475	COG0745	RESPONSE REGULATOR receiver
KM414_17490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM414_17495	COG4841	protein insertion into membrane
KM414_17500	COG0824	Thioesterase
KM414_17530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM414_17540	COG2274	protein secretion by the type I secretion system
KM414_17545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM414_17585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM414_17600	COG0183	Belongs to the thiolase family
KM414_17605	COG0318	PFAM AMP-dependent synthetase and ligase
KM414_17610	COG1268	BioY protein
KM414_17615	COG0318	PFAM AMP-dependent synthetase and ligase
KM414_17665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_17675	COG5002	protein histidine kinase activity
KM414_17680	COG0400	carboxylic ester hydrolase activity
KM414_17685	COG0346	lactoylglutathione lyase activity
KM414_17690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM414_17695	COG0069	glutamate synthase activity
KM414_17700	COG1902	pentaerythritol trinitrate reductase activity
KM414_17705	COG1329	Transcriptional regulator
KM414_17710	COG0010	Belongs to the arginase family
KM414_17735	COG2226	methyltransferase
KM414_17790	COG4846	Membrane protein involved in cytochrome C biogenesis
KM414_17795	COG0785	Cytochrome C biogenesis protein
KM414_17805	COG0583	DNA-binding transcription factor activity
KM414_17810	COG1380	Effector of murein hydrolase LrgA
KM414_17815	COG1346	cytolysis
KM414_17840	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM414_17840	COG3409	Peptidoglycan-binding domain 1 protein
KM414_17855	COG1132	(ABC) transporter
KM414_17860	COG1132	(ABC) transporter
KM414_17890	COG3639	organic phosphonate transmembrane transporter activity
KM414_17895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM414_17915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM414_17935	COG1695	Transcriptional regulator
KM414_17970	COG3409	Peptidoglycan-binding domain 1 protein
KM414_17970	COG1388	LysM domain
KM414_17970	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM414_17975	COG4824	toxin secretion phage lysis holin
KM414_18130	COG1595	DNA-templated transcription, initiation
KM414_18175	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM414_18260	COG1396	sequence-specific DNA binding
KM414_18285	COG0174	glutamine synthetase
KM414_18290	COG0789	Transcriptional regulator
KM414_18295	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM414_18305	COG2860	membrane
KM414_18315	COG0464	growth
KM414_18345	COG1388	LysM domain
KM414_18345	COG3584	3D domain protein
KM414_18350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM414_18350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM414_18350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM414_18355	COG1105	Belongs to the carbohydrate kinase PfkB family
KM414_18360	COG1349	DNA-binding transcription factor activity
KM414_18370	COG2322	membrane
KM414_18380	COG1113	amino acid transport
KM414_18395	COG1408	metallophosphoesterase
KM414_18400	COG2116	formate transmembrane transporter activity
KM414_18410	COG2217	Heavy metal translocating P-type atpase
KM414_18415	COG2608	mercury ion transmembrane transporter activity
KM414_18420	COG1937	Protein conserved in bacteria
KM414_18430	COG2819	hydrolase of the alpha beta superfamily
KM414_18435	COG1120	ATPase activity
KM414_18440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_18455	COG0708	Exodeoxyribonuclease III
KM414_18460	COG2169	Transcriptional regulator
KM414_18465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM414_18470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM414_18480	COG2364	Membrane
KM414_18495	COG2267	carboxylic ester hydrolase activity
KM414_18500	COG0346	lactoylglutathione lyase activity
KM414_18505	COG3300	MHYT domain
KM414_18505	COG5001	Diguanylate cyclase
KM414_18520	COG1346	cytolysis
KM414_18525	COG1380	Effector of murein hydrolase LrgA
KM414_18530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM414_18535	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM414_18535	COG0596	Alpha beta hydrolase
KM414_18540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM414_18560	COG1404	Belongs to the peptidase S8 family
KM414_18565	COG3773	Cell wall hydrolase
KM414_18570	COG0562	UDP-galactopyranose mutase
KM414_18575	COG1368	sulfuric ester hydrolase activity
KM414_18580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM414_18590	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM414_18615	COG1131	(ABC) transporter
KM414_18635	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM414_18640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM414_18645	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM414_18650	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM414_18650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM414_18660	COG2359	stage V sporulation protein S
KM414_18665	COG1692	metallophosphoesterase
KM414_18690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM414_18695	COG1426	Protein conserved in bacteria
KM414_18710	COG0300	oxidoreductase activity
KM414_18715	COG0612	Peptidase, M16
KM414_18720	COG0612	Peptidase, M16
KM414_18725	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM414_18735	COG3845	ABC transporter
KM414_18740	COG1744	ABC transporter substrate-binding protein PnrA-like
KM414_18745	COG2188	Transcriptional regulator
KM414_18750	COG1674	ftsk spoiiie
KM414_18760	COG0740	serine-type endopeptidase activity
KM414_18765	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM414_18775	COG0527	aspartate kinase activity
KM414_18780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM414_18785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM414_18790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM414_18795	COG1873	PFAM PRC-barrel domain
KM414_18800	COG0612	Peptidase, M16
KM414_18805	COG0726	polysaccharide deacetylase
KM414_18820	COG0196	riboflavin kinase activity
KM414_18825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM414_18835	COG1550	Protein conserved in bacteria
KM414_18845	COG1358	cellular component organization or biogenesis
KM414_18850	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM414_18855	COG0195	Participates in both transcription termination and antitermination
KM414_18875	COG0750	zinc metalloprotease
KM414_18885	COG4589	Belongs to the CDS family
KM414_18890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM414_18900	COG0528	UMP kinase activity
KM414_18930	COG4974	Belongs to the 'phage' integrase family
KM414_18940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM414_18950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM414_18990	COG1837	Belongs to the UPF0109 family
KM414_19000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM414_19010	COG0552	protein localization to endoplasmic reticulum
KM414_19015	COG1196	nuclear chromosome segregation
KM414_19025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM414_19030	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_19035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM414_19050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM414_19055	COG1461	Dihydroxyacetone kinase
KM414_19060	COG1302	Protein conserved in bacteria
KM414_19075	COG1564	THIamine pyrophosphokinase
KM414_19080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM414_19085	COG1162	GTPase activity
KM414_19090	COG0515	serine threonine protein kinase
KM414_19090	COG2815	serine threonine protein kinase
KM414_19095	COG0631	protein serine/threonine phosphatase activity
KM414_19105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM414_19105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM414_19115	COG0242	peptide deformylase activity
KM414_19120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM414_19125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM414_19145	COG1561	YicC-like family, N-terminal region
KM414_19150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM414_19160	COG0006	proline dipeptidase activity
KM414_19175	COG3069	C4-dicarboxylate transmembrane transporter activity
KM414_19240	COG0564	pseudouridine synthase activity
KM414_19260	COG3599	regulation of cell shape
KM414_19265	COG2302	S4 RNA-binding domain
KM414_19270	COG0762	integral membrane protein
KM414_19280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM414_19285	COG1496	oxidoreductase activity
KM414_19290	COG1873	PFAM PRC-barrel domain
KM414_19295	COG1191	sigma factor activity
KM414_19300	COG1191	sigma factor activity
KM414_19310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM414_19315	COG0849	cell division
KM414_19320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM414_19325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM414_19335	COG0772	Belongs to the SEDS family
KM414_19350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM414_19355	COG0768	penicillin binding
KM414_19360	COG0768	penicillin binding
KM414_19365	COG4839	cell division protein FtsL
KM414_19380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM414_19395	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM414_19400	COG1399	metal-binding, possibly nucleic acid-binding protein
KM414_19445	COG3409	Peptidoglycan-binding domain 1 protein
KM414_19445	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM414_19450	COG4824	toxin secretion phage lysis holin
KM414_19535	COG1802	Transcriptional regulator
KM414_19535	COG4626	Terminase
KM414_19560	COG0582	viral genome integration into host DNA
KM414_19625	COG0756	dUTP diphosphatase activity
KM414_19640	COG1191	sigma factor activity
KM414_19665	COG1484	DNA-dependent DNA replication
KM414_19695	COG1396	sequence-specific DNA binding
KM414_19710	COG1396	sequence-specific DNA binding
KM414_19725	COG0582	viral genome integration into host DNA
KM414_19735	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM414_19740	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM414_19745	COG3314	Sporulation integral membrane protein YlbJ
KM414_19755	COG0742	ribosomal rna small subunit methyltransferase
KM414_19770	COG3679	Belongs to the UPF0342 family
KM414_19775	COG0406	alpha-ribazole phosphatase activity
KM414_19790	COG2340	Cysteine-rich secretory protein family
KM414_19805	COG3336	cytochrome c oxidase
KM414_19840	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM414_19845	COG0772	Belongs to the SEDS family
KM414_19855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM414_19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM414_19870	COG4896	Protein conserved in bacteria
KM414_19885	COG1217	gtp-binding protein TYPA
KM414_19895	COG0483	inositol monophosphate 1-phosphatase activity
KM414_19915	COG1982	Orn Lys Arg decarboxylase major
KM414_19960	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM414_19965	COG0022	dehydrogenase e1 component
KM414_19970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM414_19980	COG0242	peptide deformylase activity
KM414_19985	COG0561	phosphatase activity
KM414_19995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM414_20000	COG0569	domain protein
KM414_20020	COG0583	DNA-binding transcription factor activity
KM414_20025	COG0517	IMP dehydrogenase activity
KM414_20035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM414_20045	COG4703	Protein of unknown function (DUF1797)
KM414_20060	COG2200	EAL domain
KM414_20065	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_20070	COG1408	metallophosphoesterase
KM414_20080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM414_20115	COG2814	Major facilitator Superfamily
KM414_20135	COG3209	COG3209 Rhs family protein
KM414_20145	COG2205	protein histidine kinase activity
KM414_20155	COG0436	Aminotransferase
KM414_20160	COG1609	Transcriptional regulator
KM414_20165	COG3833	ABC-type maltose transport systems, permease component
KM414_20170	COG1175	transmembrane transport
KM414_20175	COG2182	Extracellular solute-binding protein
KM414_20185	COG0366	Alpha amylase catalytic
KM414_20190	COG3842	ATPase activity
KM414_20230	COG0183	Belongs to the thiolase family
KM414_20265	COG1695	Transcriptional regulator
KM414_20270	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_20280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM414_20290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM414_20295	COG0436	Aminotransferase
KM414_20315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM414_20335	COG2199	diguanylate cyclase activity
KM414_20340	COG0778	Nitroreductase
KM414_20365	COG2190	(PTS) system
KM414_20365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM414_20365	COG1263	PTS System
KM414_20370	COG3711	transcriptional antiterminator
KM414_20380	COG2188	Transcriptional regulator
KM414_20390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM414_20415	COG1547	Domain of unknown function (DUF309)
KM414_20420	COG0456	acetyltransferase
KM414_20425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM414_20430	COG4086	secreted protein
KM414_20435	COG0561	phosphatase activity
KM414_20440	COG0697	spore germination
KM414_20455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_20480	COG0733	neurotransmitter:sodium symporter activity
KM414_20500	COG1686	Belongs to the peptidase S11 family
KM414_20505	COG1725	Transcriptional regulator
KM414_20510	COG1131	(ABC) transporter
KM414_20525	COG1846	Transcriptional regulator
KM414_20540	COG0598	Magnesium transport protein CorA
KM414_20565	COG4974	Belongs to the 'phage' integrase family
KM414_20575	COG0735	belongs to the Fur family
KM414_20580	COG1300	Membrane
KM414_20600	COG0667	Aldo Keto reductase
KM414_20605	COG0656	L-ascorbic acid biosynthetic process
KM414_20610	COG0456	acetyltransferase
KM414_20610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM414_20620	COG0737	Belongs to the 5'-nucleotidase family
KM414_20620	COG1525	nuclease
KM414_20620	COG4085	toxin activity
KM414_20630	COG0596	Alpha beta hydrolase
KM414_20635	COG2056	Na+-H+ antiporter family
KM414_20640	COG1609	Transcriptional regulator
KM414_20645	COG0456	acetyltransferase
KM414_20650	COG1073	alpha beta
KM414_20665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM414_20665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM414_20670	COG0307	riboflavin synthase, alpha
KM414_20695	COG4106	trans-aconitate 2-methyltransferase activity
KM414_20700	COG2226	methyltransferase
KM414_20700	COG1073	alpha beta
KM414_20715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM414_20725	COG1757	Na H antiporter
KM414_20730	COG0737	Belongs to the 5'-nucleotidase family
KM414_20740	COG1522	sequence-specific DNA binding
KM414_20760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM414_20770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM414_20785	COG0300	oxidoreductase activity
KM414_20795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM414_20800	COG1760	l-serine dehydratase
KM414_20805	COG1760	l-serine dehydratase
KM414_20825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM414_20835	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM414_20840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_20855	COG1376	ErfK ybiS ycfS ynhG family protein
KM414_20860	COG4129	membrane
KM414_20865	COG1126	abc transporter atp-binding protein
KM414_20870	COG0765	amino acid transport
KM414_20875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM414_20895	COG0772	Belongs to the SEDS family
KM414_20900	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM414_20905	COG0022	dehydrogenase e1 component
KM414_20910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM414_20915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM414_20930	COG0280	phosphate acetyltransferase
KM414_20935	COG3290	protein histidine kinase activity
KM414_20935	COG3829	transcription factor binding
KM414_20945	COG0584	glycerophosphoryl diester phosphodiesterase
KM414_20950	COG3093	addiction module antidote protein HigA
KM414_20960	COG0745	RESPONSE REGULATOR receiver
KM414_20965	COG0750	zinc metalloprotease
KM414_20970	COG0497	DNA recombination
KM414_20980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM414_20990	COG0142	geranyltranstransferase activity
KM414_21015	COG1302	Protein conserved in bacteria
KM414_21020	COG0439	Biotin carboxylase
KM414_21025	COG0511	ligase activity, forming carbon-carbon bonds
KM414_21070	COG3854	ATPases associated with a variety of cellular activities
KM414_21095	COG0006	proline dipeptidase activity
KM414_21110	COG3872	metal-dependent enzyme
KM414_21120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM414_21140	COG0095	Lipoate-protein ligase
KM414_21145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_21150	COG1609	Transcriptional regulator
KM414_21160	COG2076	Multidrug Resistance protein
KM414_21165	COG2076	Multidrug Resistance protein
KM414_21200	COG1131	(ABC) transporter
KM414_21205	COG1725	Transcriptional regulator
KM414_21235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM414_21290	COG4970	Tfp pilus assembly protein FimT
KM414_21300	COG1459	type II secretion system
KM414_21305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM414_21355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM414_21360	COG0646	methionine synthase
KM414_21360	COG1410	methionine synthase
KM414_21365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM414_21365	COG0646	methionine synthase
KM414_21370	COG0626	cystathionine gamma-synthase activity
KM414_21375	COG0626	cystathionine gamma-synthase activity
KM414_21395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_21405	COG1940	carbohydrate kinase activity
KM414_21410	COG4483	Protein conserved in bacteria
KM414_21415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM414_21420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM414_21425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM414_21430	COG0704	Plays a role in the regulation of phosphate uptake
KM414_21440	COG0581	inorganic phosphate transmembrane transporter activity
KM414_21445	COG0573	inorganic phosphate transmembrane transporter activity
KM414_21450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM414_21455	COG0768	penicillin binding
KM414_21460	COG0477	Major facilitator Superfamily
KM414_21465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM414_21490	COG0735	belongs to the Fur family
KM414_21495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM414_21500	COG1121	(ABC) transporter
KM414_21505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_21535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM414_21540	COG2384	SAM-dependent methyltransferase
KM414_21545	COG2010	Cytochrome c
KM414_21550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM414_21555	COG0358	DNA primase activity
KM414_21565	COG0517	IMP dehydrogenase activity
KM414_21580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM414_21585	COG0295	cytidine deaminase activity
KM414_21590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM414_21600	COG1480	7TM receptor with intracellular HD hydrolase
KM414_21605	COG1702	phosphate starvation-inducible protein PhoH
KM414_21620	COG1610	YqeY-like protein
KM414_21625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM414_21630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM414_21635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM414_21665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM414_21670	COG1733	regulation of RNA biosynthetic process
KM414_21695	COG1466	dna polymerase III delta subunit
KM414_21705	COG2333	competence protein COMEC
KM414_21705	COG0658	competence protein
KM414_21710	COG2131	deaminase
KM414_21715	COG1555	photosystem II stabilization
KM414_21715	COG1596	polysaccharide export
KM414_21720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM414_21725	COG2226	methyltransferase
KM414_21730	COG0799	negative regulation of ribosome biogenesis
KM414_21735	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM414_21745	COG1534	Rna-binding protein
KM414_21755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM414_21760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM414_21785	COG1595	DNA-templated transcription, initiation
KM414_21795	COG0778	Nitroreductase
KM414_21800	COG2357	RelA SpoT domain protein
KM414_21810	COG1785	Belongs to the alkaline phosphatase family
KM414_21820	COG2267	carboxylic ester hydrolase activity
KM414_21855	COG1404	Belongs to the peptidase S8 family
KM414_21860	COG3186	Phenylalanine-4-hydroxylase
KM414_21875	COG2259	Doxx family
KM414_21915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_21925	COG1454	alcohol dehydrogenase
KM414_21925	COG1012	belongs to the aldehyde dehydrogenase family
KM414_21930	COG0626	cystathionine gamma-synthase activity
KM414_21935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM414_21960	COG0768	penicillin binding
KM414_21975	COG0826	peptidase U32
KM414_21980	COG0826	peptidase U32
KM414_21985	COG4122	O-methyltransferase activity
KM414_21990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM414_22010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM414_22020	COG0628	permease
KM414_22040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM414_22050	COG0482	sulfurtransferase activity
KM414_22055	COG1104	cysteine desulfurase activity
KM414_22060	COG1959	2 iron, 2 sulfur cluster binding
KM414_22065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM414_22075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM414_22100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM414_22110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM414_22110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM414_22115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM414_22120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM414_22120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM414_22130	COG2244	polysaccharide biosynthetic process
KM414_22135	COG2323	membrane
KM414_22145	COG1862	Preprotein translocase
KM414_22175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM414_22185	COG0697	spore germination
KM414_22190	COG0697	spore germination
KM414_22195	COG0640	Transcriptional regulator
KM414_22220	COG0157	Belongs to the NadC ModD family
KM414_22225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM414_22230	COG1104	cysteine desulfurase activity
KM414_22235	COG1827	regulation of RNA biosynthetic process
KM414_22240	COG2258	MOSC domain
KM414_22245	COG0077	Prephenate dehydratase
KM414_22250	COG0577	efflux transmembrane transporter activity
KM414_22255	COG0577	efflux transmembrane transporter activity
KM414_22260	COG1136	(ABC) transporter
KM414_22270	COG0745	RESPONSE REGULATOR receiver
KM414_22275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM414_22280	COG3290	protein histidine kinase activity
KM414_22290	COG2868	ribosomal protein
KM414_22300	COG1530	ribonuclease E activity
KM414_22305	COG1994	Peptidase M50
KM414_22310	COG0739	heme binding
KM414_22315	COG2894	cell division
KM414_22335	COG1077	Cell shape determining protein MreB Mrl
KM414_22355	COG0285	dihydrofolate synthase activity
KM414_22360	COG0525	valine-tRNA ligase activity
KM414_22370	COG1388	LysM domain
KM414_22380	COG0113	porphobilinogen synthase activity
KM414_22385	COG1587	Uroporphyrinogen-III synthase
KM414_22395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM414_22405	COG1846	Transcriptional regulator
KM414_22410	COG1764	response to oxidative stress
KM414_22425	COG0470	DNA polymerase III
KM414_22425	COG1067	ATP-dependent peptidase activity
KM414_22470	COG0622	Phosphoesterase
KM414_22485	COG5401	PFAM Sporulation and spore germination
KM414_22505	COG1309	transcriptional regulator
KM414_22520	COG2197	response regulator
KM414_22525	COG2233	PERMEase
KM414_22535	COG0402	S-adenosylhomocysteine deaminase activity
KM414_22540	COG0402	S-adenosylhomocysteine deaminase activity
KM414_22550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM414_22560	COG0444	Belongs to the ABC transporter superfamily
KM414_22565	COG4608	Belongs to the ABC transporter superfamily
KM414_22570	COG3275	phosphorelay sensor kinase activity
KM414_22575	COG3279	Response regulator of the LytR AlgR family
KM414_22590	COG1983	PspC domain protein
KM414_22595	COG1396	sequence-specific DNA binding
KM414_22600	COG0697	spore germination
KM414_22610	COG1959	2 iron, 2 sulfur cluster binding
KM414_22615	COG1668	transmembrane transport
KM414_22620	COG4152	abc transporter atp-binding protein
KM414_22625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM414_22635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM414_22640	COG1876	peptidase activity
KM414_22645	COG0824	Thioesterase
KM414_22650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM414_22655	COG1053	succinate dehydrogenase
KM414_22660	COG2009	succinate dehydrogenase
KM414_22665	COG1719	4-vinyl reductase, 4VR
KM414_22675	COG3118	belongs to the thioredoxin family
KM414_22680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM414_22685	COG2086	electron transfer activity
KM414_22690	COG1024	Enoyl-CoA hydratase
KM414_22695	COG1309	transcriptional regulator
KM414_22700	COG0318	PFAM AMP-dependent synthetase and ligase
KM414_22720	COG2318	DinB family
KM414_22750	COG1131	(ABC) transporter
KM414_22755	COG2205	protein histidine kinase activity
KM414_22760	COG0745	RESPONSE REGULATOR receiver
KM414_22770	COG4895	conserved protein (DUF2196)
KM414_22775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM414_22790	COG4509	Sortase family
KM414_22795	COG1120	ATPase activity
KM414_22810	COG5386	Cell surface protein
KM414_22820	COG5386	Cell surface protein
KM414_22825	COG1114	Component of the transport system for branched-chain amino acids
KM414_22830	COG1187	pseudouridine synthase activity
KM414_22840	COG1796	DNA polymerase
KM414_22840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM414_22845	COG1286	toxin biosynthetic process
KM414_22890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM414_22900	COG1418	mRNA catabolic process
KM414_22925	COG2814	Major facilitator Superfamily
KM414_22930	COG1566	PFAM secretion protein HlyD family protein
KM414_22935	COG1309	transcriptional regulator
KM414_22940	COG1363	Peptidase, m42
KM414_22965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM414_22975	COG1484	DNA-dependent DNA replication
KM414_22980	COG3611	Membrane attachment protein
KM414_22990	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM414_22995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM414_23000	COG0237	dephospho-CoA kinase activity
KM414_23005	COG1971	Probably functions as a manganese efflux pump
KM414_23015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM414_23015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM414_23020	COG5002	protein histidine kinase activity
KM414_23025	COG0745	RESPONSE REGULATOR receiver
KM414_23045	COG0538	isocitrate dehydrogenase activity
KM414_23050	COG0372	Belongs to the citrate synthase family
KM414_23060	COG0628	permease
KM414_23065	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM414_23090	COG1725	Transcriptional regulator
KM414_23095	COG0281	malic enzyme
KM414_23100	COG0587	DNA-directed DNA polymerase activity
KM414_23115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM414_23135	COG4109	DRTGG domain
KM414_23150	COG0006	proline dipeptidase activity
KM414_23185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_23190	COG0662	Cupin 2, conserved barrel domain protein
KM414_23200	COG1476	TRANSCRIPTIONal
KM414_23215	COG1028	Short-chain dehydrogenase reductase Sdr
KM414_23220	COG0589	response to stress
KM414_23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_23280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM414_23285	COG0827	DNA restriction-modification system
KM414_23290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM414_23295	COG3874	Sporulation protein YtfJ
KM414_23310	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM414_23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM414_23335	COG1104	cysteine desulfurase activity
KM414_23345	COG0583	DNA-binding transcription factor activity
KM414_23350	COG0697	spore germination
KM414_23360	COG1956	GAF domain-containing protein
KM414_23365	COG0626	cystathionine gamma-synthase activity
KM414_23395	COG1595	DNA-templated transcription, initiation
KM414_23405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM414_23410	COG0454	-acetyltransferase
KM414_23415	COG0517	IMP dehydrogenase activity
KM414_23420	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM414_23430	COG0745	RESPONSE REGULATOR receiver
KM414_23440	COG0666	response to abiotic stimulus
KM414_23475	COG1609	Transcriptional regulator
KM414_23480	COG4851	CamS sex pheromone cAM373 precursor
KM414_23485	COG3118	belongs to the thioredoxin family
KM414_23495	COG2309	aminopeptidase activity
KM414_23515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_23530	COG1674	ftsk spoiiie
KM414_23540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM414_23545	COG4848	Belongs to the UPF0354 family
KM414_23550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM414_23555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM414_23560	COG1363	Peptidase, m42
KM414_23570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_23585	COG0510	thiamine kinase activity
KM414_23590	COG1523	belongs to the glycosyl hydrolase 13 family
KM414_23605	COG1349	DNA-binding transcription factor activity
KM414_23610	COG1187	pseudouridine synthase activity
KM414_23615	COG2244	polysaccharide biosynthetic process
KM414_23620	COG2081	HI0933 family
KM414_23625	COG2814	Major facilitator Superfamily
KM414_23635	COG3832	glyoxalase III activity
KM414_23655	COG1329	Transcriptional regulator
KM414_23665	COG4975	Glucose uptake
KM414_23680	COG0314	molybdopterin synthase activity
KM414_23685	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM414_23690	COG0303	'Molybdopterin
KM414_23700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM414_23725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM414_23735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM414_23780	COG2814	Major facilitator Superfamily
KM414_23785	COG0475	glutathione-regulated potassium exporter activity
KM414_23790	COG0490	domain, Protein
KM414_23795	COG0582	viral genome integration into host DNA
KM414_23805	COG1136	(ABC) transporter
KM414_23825	COG1242	4 iron, 4 sulfur cluster binding
KM414_23830	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM414_23835	COG1131	(ABC) transporter
KM414_23845	COG1794	racemase activity, acting on amino acids and derivatives
KM414_23865	COG2267	carboxylic ester hydrolase activity
KM414_23870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM414_23875	COG0671	phosphoesterase, PA-phosphatase related
KM414_23880	COG0438	transferase activity, transferring glycosyl groups
KM414_23890	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM414_23945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM414_23950	COG5002	protein histidine kinase activity
KM414_23955	COG4191	Histidine kinase
KM414_23960	COG2267	carboxylic ester hydrolase activity
KM414_23980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM414_23985	COG1116	anion transmembrane transporter activity
KM414_23990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM414_24015	COG0494	nUDIX hydrolase
KM414_24045	COG0288	reversible hydration of carbon dioxide
KM414_24050	COG1271	oxidase subunit
KM414_24055	COG1294	oxidase, subunit
KM414_24075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_24100	COG1842	Phage shock protein A
KM414_24130	COG5002	protein histidine kinase activity
KM414_24135	COG0745	RESPONSE REGULATOR receiver
KM414_24165	COG1597	lipid kinase activity
KM414_24200	COG0586	Pfam SNARE associated Golgi protein
KM414_24210	COG0577	efflux transmembrane transporter activity
KM414_24215	COG1136	(ABC) transporter
KM414_24220	COG2207	Transcriptional regulator
KM414_24220	COG3708	Transcriptional regulator
KM414_24225	COG0745	RESPONSE REGULATOR receiver
KM414_24230	COG2205	protein histidine kinase activity
KM414_24235	COG0577	efflux transmembrane transporter activity
KM414_24245	COG0577	efflux transmembrane transporter activity
KM414_24250	COG1136	(ABC) transporter
KM414_24270	COG2188	Transcriptional regulator
KM414_24290	COG3964	amidohydrolase
KM414_24320	COG4948	Mandelate Racemase Muconate Lactonizing
KM414_24330	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM414_24335	COG0596	Alpha beta hydrolase
KM414_24340	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM414_24345	COG1169	isochorismate synthase
KM414_24350	COG1575	Belongs to the MenA family. Type 1 subfamily
KM414_24355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM414_24375	COG0058	SHG alpha-glucan phosphorylase activity
KM414_24380	COG0297	glycogen (starch) synthase activity
KM414_24385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM414_24505	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM414_24540	COG1285	pathogenesis
KM414_24545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM414_24555	COG0166	Belongs to the GPI family
KM414_24560	COG2155	Conserved Protein
KM414_24565	COG1098	S1 RNA binding domain
KM414_24570	COG0436	Aminotransferase
KM414_24575	COG1522	sequence-specific DNA binding
KM414_24580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM414_24585	COG2267	carboxylic ester hydrolase activity
KM414_24595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM414_24615	COG5018	Exonuclease
KM414_24620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM414_24640	COG2050	protein possibly involved in aromatic compounds catabolism
KM414_24650	COG1268	BioY protein
KM414_24660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM414_24665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM414_24680	COG3584	3D domain protein
KM414_24695	COG1252	NADH dehydrogenase
KM414_24710	COG3708	Transcriptional regulator
KM414_24725	COG1683	Conserved Protein
KM414_24745	COG0316	Belongs to the HesB IscA family
KM414_24760	COG1252	NADH dehydrogenase
KM414_24775	COG0390	transport system, permease component
KM414_24780	COG2824	Alkylphosphonate utilization operon protein PhnA
KM414_24820	COG4837	Protein of unknown function (DUF1462)
KM414_24825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM414_24835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM414_24840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM414_24850	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM414_24855	COG0647	UMP catabolic process
KM414_24865	COG2445	Protein of unknown function DUF86
KM414_24870	COG1494	fructose-1,6-bisphosphatase
KM414_24885	COG4470	Protein conserved in bacteria
KM414_24895	COG0789	Transcriptional regulator
KM414_24900	COG4377	Putative membrane peptidase family (DUF2324)
KM414_24925	COG0739	heme binding
KM414_24935	COG3377	Domain of unknown function (DUF1805)
KM414_24940	COG0737	Belongs to the 5'-nucleotidase family
KM414_24945	COG1695	Transcriptional regulator
KM414_24955	COG0719	Fe-S assembly protein
KM414_24960	COG0822	iron-sulfur transferase activity
KM414_24965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM414_24970	COG0719	Fe-S assembly protein
KM414_24975	COG0396	ATPase activity
KM414_24980	COG1464	Belongs to the NlpA lipoprotein family
KM414_24985	COG1464	Belongs to the NlpA lipoprotein family
KM414_24990	COG2011	ABC-type metal ion transport system permease component
KM414_24995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM414_25005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM414_25010	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM414_25020	COG1393	Belongs to the ArsC family
KM414_25065	COG0039	L-malate dehydrogenase activity
KM414_25085	COG1309	transcriptional regulator
KM414_25090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM414_25095	COG1960	acyl-CoA dehydrogenase activity
KM414_25100	COG0183	Belongs to the thiolase family
KM414_25105	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM414_25105	COG1024	Enoyl-CoA hydratase
KM414_25115	COG1686	Belongs to the peptidase S11 family
KM414_25130	COG0011	TIGRFAM Protein of
KM414_25135	COG0840	transmembrane signaling receptor activity
KM414_25155	COG2814	Major facilitator Superfamily
KM414_25160	COG0531	amino acid
KM414_25170	COG0706	membrane insertase activity
KM414_25180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM414_25215	COG0586	Pfam SNARE associated Golgi protein
KM414_25225	COG1376	ErfK ybiS ycfS ynhG family protein
KM414_25230	COG0745	RESPONSE REGULATOR receiver
KM414_25235	COG5002	protein histidine kinase activity
KM414_25260	COG2151	metal-sulfur cluster biosynthetic enzyme
KM414_25265	COG3227	Zinc metalloprotease (Elastase)
KM414_25270	COG1741	Belongs to the pirin family
KM414_25285	COG0475	glutathione-regulated potassium exporter activity
KM414_25290	COG0490	domain, Protein
KM414_25295	COG1115	amino acid carrier protein
KM414_25300	COG0783	Belongs to the Dps family
KM414_25315	COG1611	Belongs to the LOG family
KM414_25335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_25340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_25345	COG1115	amino acid carrier protein
KM414_25350	COG1115	amino acid carrier protein
KM414_25355	COG2910	NAD(P)H-binding
KM414_25370	COG0656	L-ascorbic acid biosynthetic process
KM414_25375	COG2814	Major facilitator Superfamily
KM414_25380	COG1733	regulation of RNA biosynthetic process
KM414_25390	COG1252	NADH dehydrogenase
KM414_25395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM414_25400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM414_25410	COG0840	transmembrane signaling receptor activity
KM414_25410	COG3290	protein histidine kinase activity
KM414_25420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM414_25425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM414_25440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM414_25495	COG0557	exoribonuclease II activity
KM414_25500	COG1647	Serine aminopeptidase, S33
KM414_25505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM414_25510	COG1346	cytolysis
KM414_25610	COG4695	Portal protein
KM414_25635	COG4974	Belongs to the 'phage' integrase family
KM414_25645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM414_25650	COG0149	triose-phosphate isomerase activity
KM414_25660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM414_25675	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM414_25700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM414_25715	COG2323	membrane
KM414_25720	COG0740	serine-type endopeptidase activity
KM414_25725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM414_25735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM414_25745	COG1051	belongs to the nudix hydrolase family
KM414_25755	COG0492	ferredoxin-NADP+ reductase activity
KM414_25760	COG0457	Tetratricopeptide repeat
KM414_25765	COG0110	maltose O-acetyltransferase activity
KM414_25785	COG1950	PFAM Membrane protein of
KM414_25795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM414_25800	COG0556	nucleotide-excision repair
KM414_25820	COG0789	Transcriptional regulator
KM414_25845	COG2855	membrane
KM414_25850	COG0583	DNA-binding transcription factor activity
KM414_25860	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM414_25865	COG0488	(ABC) transporter
KM414_25875	COG1132	(ABC) transporter
KM414_25880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM414_25885	COG0793	Belongs to the peptidase S41A family
KM414_25885	COG3409	Peptidoglycan-binding domain 1 protein
KM414_25890	COG2177	Part of the ABC transporter FtsEX involved in
KM414_25895	COG2884	Cell division ATP-binding protein ftsE
KM414_25910	COG0653	protein targeting
KM414_25915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM414_25920	COG1278	Cold shock
KM414_25925	COG1040	competence protein
KM414_25930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM414_25935	COG1388	LysM domain
KM414_25935	COG0791	NLP P60 protein
KM414_25940	COG1733	regulation of RNA biosynthetic process
KM414_25945	COG1307	EDD domain protein, DegV family
KM414_25950	COG1739	Uncharacterized protein family UPF0029
KM414_25955	COG1316	TRANSCRIPTIONal
KM414_25960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM414_25965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM414_25970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM414_25980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM414_25980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM414_25995	COG3394	polysaccharide catabolic process
KM414_26000	COG1486	melibiose metabolic process
KM414_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM414_26010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM414_26020	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM414_26025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM414_26030	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM414_26040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM414_26045	COG1301	dicarboxylic acid transport
KM414_26055	COG0346	lactoylglutathione lyase activity
KM414_26060	COG1511	domain protein
KM414_26065	COG0583	DNA-binding transcription factor activity
KM414_26070	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM414_26085	COG1271	oxidase subunit
KM414_26090	COG1294	oxidase, subunit
KM414_26095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM414_26115	COG2389	metal-binding protein
KM414_26125	COG1368	sulfuric ester hydrolase activity
KM414_26140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM414_26150	COG1215	transferase activity, transferring glycosyl groups
KM414_26155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM414_26160	COG1388	LysM domain
KM414_26160	COG3584	3D domain protein
KM414_26185	COG4715	Zinc finger, swim domain protein
KM414_26190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM414_26230	COG0577	efflux transmembrane transporter activity
KM414_26235	COG1136	(ABC) transporter
KM414_26270	COG5002	protein histidine kinase activity
KM414_26275	COG0745	RESPONSE REGULATOR receiver
KM414_26280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM414_26295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM414_26300	COG1134	teichoic acid transport
KM414_26305	COG1682	transport, permease protein
KM414_26310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM414_26355	COG1609	Transcriptional regulator
KM414_26370	COG0739	heme binding
KM414_26390	COG2385	sporulation resulting in formation of a cellular spore
KM414_26405	COG4836	Membrane
KM414_26410	COG1007	ATP synthesis coupled electron transport
KM414_26415	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM414_26420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM414_26430	COG0839	Belongs to the complex I subunit 6 family
KM414_26445	COG0649	NAD binding
KM414_26450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM414_26465	COG3300	MHYT domain
KM414_26465	COG5001	Diguanylate cyclase
KM414_26515	COG0356	it plays a direct role in the translocation of protons across the membrane
KM414_26550	COG0698	ribose 5-phosphate isomerase
KM414_26560	COG2190	(PTS) system
KM414_26565	COG2259	Doxx family
KM414_26570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM414_26585	COG0009	L-threonylcarbamoyladenylate synthase
KM414_26600	COG2890	protein-(glutamine-N5) methyltransferase activity
KM414_26620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM414_26625	COG1494	fructose-1,6-bisphosphatase
KM414_26645	COG4821	SIS domain
KM414_26655	COG3343	RNA polymerase activity
KM414_26665	COG1960	acyl-CoA dehydrogenase activity
KM414_26670	COG1960	acyl-CoA dehydrogenase activity
KM414_26675	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM414_26680	COG0183	Belongs to the thiolase family
KM414_26685	COG2181	nitrate reductase activity
KM414_26685	COG0247	lactate metabolic process
KM414_26690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM414_26700	COG3300	MHYT domain
KM414_26700	COG5001	Diguanylate cyclase
KM414_26720	COG2197	response regulator
KM414_26725	COG4585	Histidine kinase
KM414_26730	COG0842	Transport permease protein
KM414_26735	COG1131	(ABC) transporter
KM414_26740	COG0024	Methionine aminopeptidase
KM414_26750	COG2234	aminopeptidase activity
KM414_26770	COG1595	DNA-templated transcription, initiation
KM414_26775	COG0018	arginyl-trna synthetase
KM414_26780	COG4506	Protein conserved in bacteria
KM414_26785	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM414_26800	COG0010	Belongs to the arginase family
KM414_26810	COG2814	Major facilitator Superfamily
KM414_26815	COG0789	Transcriptional regulator
KM414_26820	COG0584	glycerophosphoryl diester phosphodiesterase
KM414_26825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM414_26835	COG1994	Peptidase M50
KM414_26845	COG1078	dGTPase activity
KM414_26850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM414_26855	COG1120	ATPase activity
KM414_26860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM414_26885	COG0095	Lipoate-protein ligase
KM414_26890	COG0280	phosphate acetyltransferase
KM414_26905	COG3773	Cell wall hydrolase
KM414_26915	COG2363	Small membrane protein
KM414_26925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM414_26930	COG2233	PERMEase
KM414_26935	COG0561	phosphatase activity
KM414_26940	COG2814	Major facilitator Superfamily
KM414_26950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM414_26955	COG1131	(ABC) transporter
KM414_26960	COG2755	lipolytic protein G-D-S-L family
KM414_26965	COG1609	Transcriptional regulator
KM414_26975	COG0460	homoserine dehydrogenase
KM414_26985	COG2873	o-acetylhomoserine
KM414_26995	COG1011	Hydrolase
KM414_27000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM414_27010	COG2197	response regulator
KM414_27020	COG0351	phosphomethylpyrimidine kinase
KM414_27025	COG3706	GGDEF domain
KM414_27030	COG2879	small protein
KM414_27035	COG1966	Carbon starvation protein
KM414_27040	COG3279	Response regulator of the LytR AlgR family
KM414_27045	COG0477	Major facilitator Superfamily
KM414_27070	COG0840	transmembrane signaling receptor activity
KM414_27080	COG1607	acyl-coa hydrolase
KM414_27095	COG0488	(ABC) transporter
KM414_27115	COG0463	Glycosyl transferase, family 2
KM414_27120	COG1309	transcriptional regulator
KM414_27125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM414_27130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM414_27130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM414_27135	COG0628	permease
KM414_27150	COG3279	Response regulator of the LytR AlgR family
KM414_27155	COG3275	phosphorelay sensor kinase activity
KM414_27160	COG2814	Major facilitator Superfamily
KM414_27165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM414_27170	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM414_27175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM414_27195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM414_27200	COG1272	protein, Hemolysin III
KM414_27220	COG0516	GMP reductase activity
KM414_27225	COG1164	Oligoendopeptidase f
KM414_27245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM414_27250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM414_27255	COG4853	Protein conserved in bacteria
KM414_27260	COG4863	YycH protein
KM414_27265	COG5002	protein histidine kinase activity
KM414_27270	COG0745	RESPONSE REGULATOR receiver
KM414_27300	COG0305	Participates in initiation and elongation during chromosome replication
KM414_27310	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM414_27315	COG4241	membrane
KM414_27325	COG0629	single-stranded DNA binding
KM414_27335	COG0012	GTP binding
KM414_27340	COG4481	Protein conserved in bacteria
KM414_27345	COG0668	transmembrane transport
KM414_27355	COG1475	DNA binding
KM414_27360	COG1192	Involved in chromosome partitioning
KM414_27385	COG1847	R3H domain protein
KM414_27390	COG0706	membrane insertase activity
KM414_27400	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM414_27455	COG3344	reverse transcriptase
KM414_27535	COG3344	reverse transcriptase
KM414_27730	COG4962	Type ii secretion system protein e
KM414_27865	COG2311	Membrane
KM414_27885	COG4196	transglutaminase domain protein
KM414_27890	COG0671	phosphoesterase, PA-phosphatase related
KM414_27905	COG1215	transferase activity, transferring glycosyl groups
KM414_27910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM414_27915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM414_28080	COG2002	toxin-antitoxin pair type II binding
KM414_28090	COG4974	Belongs to the 'phage' integrase family
KM414_28145	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM414_28155	COG4974	Belongs to the 'phage' integrase family
KM414_28180	COG0457	Tetratricopeptide repeat
KM414_28385	COG0741	lytic transglycosylase activity
KM414_28385	COG0791	NLP P60 protein
KM414_28450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM414_28505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM414_28515	COG4166	transmembrane transport
KM414_28555	COG1280	lysine exporter protein (LysE YggA)
KM414_28580	COG0681	Belongs to the peptidase S26 family
KM414_28655	COG1309	transcriptional regulator
KM414_28660	COG1683	Conserved Protein
KM414_28700	COG1192	Involved in chromosome partitioning