locus-tag	class	description
KM417_00010	COG0592	DNA-directed DNA polymerase activity
KM417_00015	COG2501	S4 domain
KM417_00025	COG0187	DNA topoisomerase II activity
KM417_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM417_00065	COG0516	GMP reductase activity
KM417_00065	COG0517	IMP dehydrogenase activity
KM417_00070	COG1686	Belongs to the peptidase S11 family
KM417_00100	COG1428	Deoxynucleoside kinase
KM417_00105	COG1428	Deoxynucleoside kinase
KM417_00110	COG1335	isochorismatase
KM417_00115	COG0590	tRNA wobble adenosine to inosine editing
KM417_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM417_00180	COG1982	Orn Lys Arg decarboxylase major
KM417_00190	COG0470	DNA polymerase III
KM417_00195	COG1774	PSP1 C-terminal conserved region
KM417_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM417_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM417_00220	COG2002	toxin-antitoxin pair type II binding
KM417_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_00230	COG0084	hydrolase, TatD family'
KM417_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM417_00250	COG4466	Protein conserved in bacteria
KM417_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM417_00270	COG0251	oxidation-reduction process
KM417_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM417_00305	COG2002	toxin-antitoxin pair type II binding
KM417_00310	COG2244	polysaccharide biosynthetic process
KM417_00315	COG3956	TIGRFAM MazG family protein
KM417_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM417_00340	COG1098	S1 RNA binding domain
KM417_00355	COG2208	phosphoserine phosphatase activity
KM417_00360	COG0037	tRNA processing
KM417_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM417_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM417_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM417_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM417_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM417_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM417_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM417_00420	COG1396	sequence-specific DNA binding
KM417_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM417_00455	COG3880	PFAM UvrB UvrC protein
KM417_00465	COG0542	response to heat
KM417_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM417_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM417_00500	COG1045	serine acetyltransferase
KM417_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM417_00520	COG3688	RNA-binding protein containing a PIN domain
KM417_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM417_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM417_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM417_00565	COG2813	Specifically methylates the guanine in position
KM417_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM417_00580	COG1358	cellular component organization or biogenesis
KM417_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM417_00710	COG0201	protein transport
KM417_00720	COG0024	Methionine aminopeptidase
KM417_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM417_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM417_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_00795	COG0489	protein tyrosine kinase activity
KM417_00805	COG2194	sulfuric ester hydrolase activity
KM417_00810	COG0726	polysaccharide deacetylase
KM417_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM417_00895	COG4856	YbbR-like protein
KM417_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM417_00915	COG0596	Alpha beta hydrolase
KM417_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM417_00940	COG4946	Tricorn protease homolog
KM417_00940	COG1506	peptidase
KM417_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM417_00975	COG2011	ABC-type metal ion transport system permease component
KM417_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_00985	COG1464	Belongs to the NlpA lipoprotein family
KM417_00990	COG0604	alcohol dehydrogenase
KM417_01000	COG0277	FAD linked oxidase domain protein
KM417_01005	COG2271	Major facilitator Superfamily
KM417_01015	COG2814	Major facilitator Superfamily
KM417_01030	COG0601	transmembrane transport
KM417_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_01040	COG0444	Belongs to the ABC transporter superfamily
KM417_01045	COG4608	Belongs to the ABC transporter superfamily
KM417_01050	COG4166	transmembrane transport
KM417_01060	COG2207	Transcriptional regulator
KM417_01075	COG4166	transmembrane transport
KM417_01080	COG4166	transmembrane transport
KM417_01085	COG0656	L-ascorbic acid biosynthetic process
KM417_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_01105	COG4149	molybdate abc transporter
KM417_01115	COG1910	domain protein
KM417_01125	COG0583	DNA-binding transcription factor activity
KM417_01130	COG0697	spore germination
KM417_01145	COG0204	Acyl-transferase
KM417_01155	COG1609	Transcriptional regulator
KM417_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_01175	COG0084	hydrolase, TatD family'
KM417_01180	COG5298	Protein conserved in bacteria
KM417_01205	COG0488	(ABC) transporter
KM417_01220	COG0747	negative chemotaxis
KM417_01225	COG0601	transmembrane transport
KM417_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_01235	COG0444	Belongs to the ABC transporter superfamily
KM417_01240	COG4608	Belongs to the ABC transporter superfamily
KM417_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM417_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM417_01290	COG2814	Major facilitator Superfamily
KM417_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM417_01310	COG4294	response to UV
KM417_01315	COG0457	Tetratricopeptide repeat
KM417_01315	COG0705	Rhomboid family
KM417_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM417_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM417_01335	COG0864	Transcriptional regulator
KM417_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM417_01345	COG2183	response to ionizing radiation
KM417_01440	COG0802	atpase or kinase
KM417_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM417_01450	COG0456	acetyltransferase
KM417_01460	COG0488	(ABC) transporter
KM417_01475	COG1266	CAAX protease self-immunity
KM417_01495	COG2252	PERMEase
KM417_01505	COG5002	protein histidine kinase activity
KM417_01535	COG2226	methyltransferase
KM417_01575	COG1968	undecaprenyl-diphosphatase activity
KM417_01590	COG2205	protein histidine kinase activity
KM417_01595	COG0745	RESPONSE REGULATOR receiver
KM417_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM417_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM417_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM417_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM417_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM417_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM417_01670	COG0151	Belongs to the GarS family
KM417_01695	COG0210	DNA helicase
KM417_01705	COG4851	CamS sex pheromone cAM373 precursor
KM417_01725	COG1335	isochorismatase
KM417_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_01735	COG2011	ABC-type metal ion transport system permease component
KM417_01740	COG1464	Belongs to the NlpA lipoprotein family
KM417_01760	COG1846	Transcriptional regulator
KM417_01785	COG1597	lipid kinase activity
KM417_01790	COG0546	phosphoglycolate phosphatase activity
KM417_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM417_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM417_01810	COG2076	Multidrug Resistance protein
KM417_01815	COG2309	aminopeptidase activity
KM417_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM417_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM417_01850	COG4807	Protein conserved in bacteria
KM417_01875	COG1757	Na H antiporter
KM417_01880	COG1473	amidohydrolase
KM417_01895	COG0450	alkyl hydroperoxide reductase
KM417_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_01940	COG0166	Belongs to the GPI family
KM417_01975	COG5002	protein histidine kinase activity
KM417_01995	COG3541	Predicted nucleotidyltransferase
KM417_02000	COG2814	Major facilitator Superfamily
KM417_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM417_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_02015	COG0765	amino acid transport
KM417_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_02030	COG0840	transmembrane signaling receptor activity
KM417_02035	COG0840	transmembrane signaling receptor activity
KM417_02040	COG0366	Alpha amylase catalytic
KM417_02045	COG2190	(PTS) system
KM417_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_02045	COG1263	PTS System
KM417_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM417_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_02100	COG1116	anion transmembrane transporter activity
KM417_02105	COG0488	(ABC) transporter
KM417_02150	COG2270	Major facilitator Superfamily
KM417_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_02180	COG2310	stress, protein
KM417_02185	COG2310	stress, protein
KM417_02190	COG2310	stress, protein
KM417_02195	COG0861	Integral membrane protein TerC family
KM417_02205	COG3853	Toxic anion resistance protein (TelA)
KM417_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM417_02230	COG1295	ribonuclease BN
KM417_02235	COG2217	Heavy metal translocating P-type atpase
KM417_02240	COG0697	spore germination
KM417_02260	COG0586	Pfam SNARE associated Golgi protein
KM417_02275	COG3871	stress protein (general stress protein 26)
KM417_02280	COG0387	Pfam Sodium calcium exchanger
KM417_02290	COG0535	radical SAM domain protein
KM417_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM417_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM417_02325	COG0582	viral genome integration into host DNA
KM417_02335	COG1396	sequence-specific DNA binding
KM417_02350	COG1396	sequence-specific DNA binding
KM417_02385	COG1484	DNA-dependent DNA replication
KM417_02615	COG0101	tRNA pseudouridine synthase activity
KM417_02625	COG3829	transcription factor binding
KM417_02635	COG0833	amino acid
KM417_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM417_02670	COG1263	PTS System
KM417_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_02690	COG0463	Glycosyl transferase, family 2
KM417_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM417_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM417_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM417_02745	COG1228	amidohydrolase
KM417_02750	COG1090	epimerase
KM417_02780	COG1988	membrane-bound metal-dependent
KM417_02785	COG1194	a g-specific adenine glycosylase
KM417_02810	COG1132	(ABC) transporter
KM417_02815	COG4129	membrane
KM417_02820	COG0067	glutamate synthase
KM417_02820	COG0069	glutamate synthase activity
KM417_02820	COG0070	glutamate synthase
KM417_02830	COG4555	ABC transporter
KM417_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM417_02855	COG0735	belongs to the Fur family
KM417_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM417_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM417_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM417_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM417_03005	COG2766	serine protein kinase
KM417_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM417_03040	COG2268	Band 7 protein
KM417_03050	COG3290	protein histidine kinase activity
KM417_03055	COG4565	transcriptional regulatory protein
KM417_03060	COG2851	Citrate transporter
KM417_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM417_03085	COG3842	ATPase activity
KM417_03090	COG1175	transmembrane transport
KM417_03095	COG0395	ABC-type sugar transport system, permease component
KM417_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM417_03110	COG0745	RESPONSE REGULATOR receiver
KM417_03115	COG5002	protein histidine kinase activity
KM417_03125	COG4990	cell redox homeostasis
KM417_03135	COG3290	protein histidine kinase activity
KM417_03140	COG4565	transcriptional regulatory protein
KM417_03145	COG3493	citrate carrier protein
KM417_03150	COG0281	malic enzyme
KM417_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_03175	COG5002	protein histidine kinase activity
KM417_03180	COG0745	RESPONSE REGULATOR receiver
KM417_03185	COG0456	acetyltransferase
KM417_03185	COG0454	-acetyltransferase
KM417_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM417_03195	COG3383	formate dehydrogenase (NAD+) activity
KM417_03200	COG2427	Protein of unknown function (DUF1641)
KM417_03215	COG0531	amino acid
KM417_03220	COG0640	Transcriptional regulator
KM417_03225	COG2217	Heavy metal translocating P-type atpase
KM417_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM417_03245	COG3227	Zinc metalloprotease (Elastase)
KM417_03265	COG2720	vancomycin resistance protein
KM417_03270	COG1316	TRANSCRIPTIONal
KM417_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_03280	COG0346	lactoylglutathione lyase activity
KM417_03285	COG1253	flavin adenine dinucleotide binding
KM417_03290	COG1027	Aspartate ammonia-lyase
KM417_03295	COG1620	l-lactate permease
KM417_03310	COG3104	oligopeptide transport
KM417_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_03335	COG2226	methyltransferase
KM417_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM417_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM417_03355	COG4548	von Willebrand factor, type A
KM417_03360	COG0714	Associated with various cellular activities
KM417_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_03385	COG0531	amino acid
KM417_03390	COG2188	Transcriptional regulator
KM417_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_03395	COG1263	PTS System
KM417_03400	COG0366	Alpha amylase catalytic
KM417_03415	COG0697	spore germination
KM417_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_03430	COG1115	amino acid carrier protein
KM417_03435	COG1126	abc transporter atp-binding protein
KM417_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_03445	COG0765	amino acid transport
KM417_03450	COG0765	amino acid transport
KM417_03455	COG0833	amino acid
KM417_03480	COG2378	regulation of single-species biofilm formation
KM417_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM417_03490	COG5002	protein histidine kinase activity
KM417_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM417_03520	COG0747	negative chemotaxis
KM417_03530	COG0601	transmembrane transport
KM417_03535	COG4608	Belongs to the ABC transporter superfamily
KM417_03545	COG2271	Major facilitator Superfamily
KM417_03550	COG1846	Transcriptional regulator
KM417_03560	COG1609	Transcriptional regulator
KM417_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM417_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM417_03585	COG1879	ABC-type sugar transport system periplasmic component
KM417_03610	COG1063	alcohol dehydrogenase
KM417_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM417_03650	COG1968	undecaprenyl-diphosphatase activity
KM417_03655	COG0840	transmembrane signaling receptor activity
KM417_03660	COG3584	3D domain protein
KM417_03660	COG1388	LysM domain
KM417_03665	COG1476	TRANSCRIPTIONal
KM417_03680	COG3104	oligopeptide transport
KM417_03685	COG1114	Component of the transport system for branched-chain amino acids
KM417_03700	COG1113	amino acid transport
KM417_03705	COG2252	PERMEase
KM417_03730	COG0475	glutathione-regulated potassium exporter activity
KM417_03730	COG0569	domain protein
KM417_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM417_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM417_03755	COG0833	amino acid
KM417_03760	COG4990	cell redox homeostasis
KM417_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_03780	COG0697	spore germination
KM417_03785	COG0531	amino acid
KM417_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM417_03805	COG1918	ferrous iron import across plasma membrane
KM417_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM417_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM417_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM417_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM417_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM417_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM417_03975	COG1116	anion transmembrane transporter activity
KM417_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM417_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_04000	COG2104	thiamine diphosphate biosynthetic process
KM417_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_04015	COG0351	phosphomethylpyrimidine kinase
KM417_04055	COG2205	protein histidine kinase activity
KM417_04060	COG2814	Major facilitator Superfamily
KM417_04065	COG1846	Transcriptional regulator
KM417_04080	COG2252	PERMEase
KM417_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM417_04105	COG1621	beta-fructofuranosidase activity
KM417_04110	COG1263	PTS System
KM417_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_04115	COG1609	Transcriptional regulator
KM417_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM417_04165	COG0778	Nitroreductase
KM417_04170	COG2719	SpoVR family
KM417_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM417_04200	COG1937	Protein conserved in bacteria
KM417_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM417_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM417_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM417_04235	COG0730	response to heat
KM417_04245	COG1316	TRANSCRIPTIONal
KM417_04250	COG0604	alcohol dehydrogenase
KM417_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM417_04270	COG3711	transcriptional antiterminator
KM417_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_04300	COG1388	LysM domain
KM417_04300	COG3584	3D domain protein
KM417_04305	COG0577	efflux transmembrane transporter activity
KM417_04310	COG1136	(ABC) transporter
KM417_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM417_04335	COG1114	Component of the transport system for branched-chain amino acids
KM417_04340	COG3546	catalase activity
KM417_04375	COG0586	Pfam SNARE associated Golgi protein
KM417_04410	COG0531	amino acid
KM417_04415	COG0475	glutathione-regulated potassium exporter activity
KM417_04425	COG1737	Transcriptional regulator
KM417_04435	COG1263	PTS System
KM417_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_04445	COG2259	Doxx family
KM417_04460	COG0697	spore germination
KM417_04465	COG1522	sequence-specific DNA binding
KM417_04480	COG2076	Multidrug Resistance protein
KM417_04485	COG1309	transcriptional regulator
KM417_04490	COG2814	Major facilitator Superfamily
KM417_04495	COG1733	regulation of RNA biosynthetic process
KM417_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_04510	COG4533	DNA binding
KM417_04515	COG2211	Major facilitator Superfamily
KM417_04525	COG0693	protein deglycase activity
KM417_04530	COG0693	protein deglycase activity
KM417_04530	COG0753	catalase activity
KM417_04540	COG0531	amino acid
KM417_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM417_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM417_04560	COG1132	(ABC) transporter
KM417_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_04575	COG0765	amino acid transport
KM417_04580	COG1126	abc transporter atp-binding protein
KM417_04595	COG0189	ligase activity
KM417_04625	COG0028	Belongs to the TPP enzyme family
KM417_04630	COG3527	Alpha-acetolactate decarboxylase
KM417_04645	COG0561	phosphatase activity
KM417_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM417_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM417_04695	COG0653	protein targeting
KM417_04700	COG2244	polysaccharide biosynthetic process
KM417_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_04715	COG4196	transglutaminase domain protein
KM417_04730	COG1696	Membrane protein involved in D-alanine export
KM417_04745	COG1024	Enoyl-CoA hydratase
KM417_04765	COG1363	Peptidase, m42
KM417_04785	COG3938	Belongs to the proline racemase family
KM417_04825	COG0601	transmembrane transport
KM417_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_04840	COG4608	Belongs to the ABC transporter superfamily
KM417_04845	COG0322	excinuclease ABC activity
KM417_04875	COG0477	Major facilitator Superfamily
KM417_04880	COG3290	protein histidine kinase activity
KM417_04885	COG4565	transcriptional regulatory protein
KM417_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM417_04920	COG0789	Transcriptional regulator
KM417_04920	COG4978	Transcriptional regulator
KM417_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM417_04975	COG0477	Major facilitator Superfamily
KM417_05020	COG3320	Male sterility
KM417_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_05025	COG1309	transcriptional regulator
KM417_05045	COG1183	phosphatidylcholine synthase activity
KM417_05065	COG2376	Dihydroxyacetone kinase
KM417_05075	COG2376	Dihydroxyacetone kinase
KM417_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_05085	COG1959	2 iron, 2 sulfur cluster binding
KM417_05115	COG3437	response regulator, receiver
KM417_05115	COG2770	Histidine kinase
KM417_05165	COG3237	CsbD-like
KM417_05190	COG1191	sigma factor activity
KM417_05200	COG2208	phosphoserine phosphatase activity
KM417_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM417_05210	COG2205	protein histidine kinase activity
KM417_05210	COG0784	Response regulator, receiver
KM417_05210	COG2198	Histidine kinase
KM417_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_05265	COG0420	3'-5' exonuclease activity
KM417_05270	COG4717	serine-type aminopeptidase activity
KM417_05290	COG1309	transcriptional regulator
KM417_05295	COG2814	Major facilitator Superfamily
KM417_05300	COG0346	lactoylglutathione lyase activity
KM417_05310	COG0346	lactoylglutathione lyase activity
KM417_05315	COG0457	Tetratricopeptide repeat
KM417_05320	COG2267	carboxylic ester hydrolase activity
KM417_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM417_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM417_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM417_05395	COG0477	Major facilitator Superfamily
KM417_05400	COG0477	Major facilitator Superfamily
KM417_05410	COG3973	AAA domain
KM417_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_05435	COG4980	gas vesicle protein
KM417_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM417_05445	COG1131	(ABC) transporter
KM417_05450	COG4473	ABC transporter
KM417_05465	COG1309	transcriptional regulator
KM417_05475	COG3402	PFAM membrane-flanked domain
KM417_05525	COG3402	PFAM membrane-flanked domain
KM417_05530	COG3428	Bacterial PH domain
KM417_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM417_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM417_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM417_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM417_05590	COG1309	transcriptional regulator
KM417_05595	COG1511	domain protein
KM417_05620	COG1609	Transcriptional regulator
KM417_05630	COG1234	tRNA 3'-trailer cleavage
KM417_05635	COG0095	Lipoate-protein ligase
KM417_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_05675	COG3209	COG3209 Rhs family protein
KM417_05715	COG1078	dGTPase activity
KM417_05725	COG1595	DNA-templated transcription, initiation
KM417_05730	COG3708	Transcriptional regulator
KM417_05730	COG2207	Transcriptional regulator
KM417_05745	COG2205	protein histidine kinase activity
KM417_05750	COG0745	RESPONSE REGULATOR receiver
KM417_05775	COG0501	Belongs to the peptidase M48B family
KM417_05780	COG0840	transmembrane signaling receptor activity
KM417_05785	COG0697	spore germination
KM417_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM417_05810	COG2224	Isocitrate lyase
KM417_05835	COG4903	ComK protein
KM417_05840	COG0398	Pfam SNARE associated Golgi protein
KM417_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM417_05855	COG1074	ATP-dependent DNA helicase activity
KM417_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM417_05925	COG0367	asparagine synthase
KM417_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM417_05935	COG0753	catalase activity
KM417_05940	COG0004	ammonium transporteR
KM417_05960	COG2996	Protein conserved in bacteria
KM417_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_05995	COG0561	phosphatase activity
KM417_06005	COG0542	response to heat
KM417_06015	COG2267	carboxylic ester hydrolase activity
KM417_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM417_06040	COG5504	Zn-dependent protease
KM417_06050	COG0180	Tryptophanyl-tRNA synthetase
KM417_06060	COG4166	transmembrane transport
KM417_06065	COG0601	transmembrane transport
KM417_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_06075	COG0444	Belongs to the ABC transporter superfamily
KM417_06080	COG4608	Belongs to the ABC transporter superfamily
KM417_06085	COG0534	Mate efflux family protein
KM417_06090	COG4166	transmembrane transport
KM417_06105	COG0861	Integral membrane protein TerC family
KM417_06110	COG4862	establishment of competence for transformation
KM417_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_06125	COG1164	Oligoendopeptidase f
KM417_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM417_06140	COG2346	COG2346, Truncated hemoglobins
KM417_06145	COG4116	CYTH
KM417_06155	COG2357	RelA SpoT domain protein
KM417_06165	COG0564	pseudouridine synthase activity
KM417_06185	COG0463	Glycosyl transferase, family 2
KM417_06185	COG1216	Glycosyl transferase, family 2
KM417_06205	COG0457	Tetratricopeptide repeat
KM417_06205	COG0463	Glycosyl transferase, family 2
KM417_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM417_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM417_06285	COG2153	protein acetylation
KM417_06295	COG2382	esterase
KM417_06310	COG5492	domain, Protein
KM417_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM417_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM417_06360	COG1620	l-lactate permease
KM417_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM417_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_06430	COG1476	TRANSCRIPTIONal
KM417_06490	COG2226	methyltransferase
KM417_06500	COG1686	Belongs to the peptidase S11 family
KM417_06505	COG0681	Belongs to the peptidase S26 family
KM417_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM417_06545	COG3842	ATPase activity
KM417_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM417_06555	COG1177	transmembrane transport
KM417_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM417_06570	COG2409	Drug exporters of the RND superfamily
KM417_06580	COG0564	pseudouridine synthase activity
KM417_06590	COG2340	Cysteine-rich secretory protein family
KM417_06595	COG0247	lactate metabolic process
KM417_06600	COG0277	FAD linked oxidase domain protein
KM417_06605	COG3835	regulator
KM417_06615	COG0745	RESPONSE REGULATOR receiver
KM417_06620	COG5002	protein histidine kinase activity
KM417_06625	COG2186	Transcriptional regulator
KM417_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM417_06660	COG2116	formate transmembrane transporter activity
KM417_06665	COG0861	Integral membrane protein TerC family
KM417_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_06680	COG2030	dehydratase
KM417_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM417_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM417_06760	COG1349	DNA-binding transcription factor activity
KM417_06780	COG2861	carbohydrate metabolic process
KM417_06790	COG3852	Histidine kinase
KM417_06795	COG1846	Transcriptional regulator
KM417_06805	COG2318	DinB family
KM417_06810	COG5002	protein histidine kinase activity
KM417_06820	COG0720	synthase
KM417_06835	COG4873	Protein conserved in bacteria
KM417_06865	COG1780	Probably involved in ribonucleotide reductase function
KM417_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM417_06890	COG1725	Transcriptional regulator
KM417_06895	COG1131	(ABC) transporter
KM417_06905	COG1131	(ABC) transporter
KM417_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_06925	COG1522	sequence-specific DNA binding
KM417_06935	COG1335	isochorismatase
KM417_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_06950	COG2070	2-Nitropropane dioxygenase
KM417_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM417_06965	COG1696	Membrane protein involved in D-alanine export
KM417_06990	COG0716	FMN binding
KM417_07005	COG3173	Aminoglycoside phosphotransferase
KM417_07025	COG0534	Mate efflux family protein
KM417_07030	COG1968	undecaprenyl-diphosphatase activity
KM417_07045	COG1846	Transcriptional regulator
KM417_07055	COG1301	dicarboxylic acid transport
KM417_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM417_07065	COG4709	membrane
KM417_07070	COG3874	Sporulation protein YtfJ
KM417_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_07100	COG0028	Belongs to the TPP enzyme family
KM417_07105	COG0440	acetolactate synthase activity
KM417_07110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM417_07120	COG0473	3-isopropylmalate dehydrogenase activity
KM417_07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM417_07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM417_07195	COG1183	phosphatidylcholine synthase activity
KM417_07200	COG1368	sulfuric ester hydrolase activity
KM417_07210	COG0019	diaminopimelate decarboxylase activity
KM417_07230	COG0529	Catalyzes the synthesis of activated sulfate
KM417_07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM417_07255	COG1648	precorrin-2 dehydrogenase activity
KM417_07260	COG0733	neurotransmitter:sodium symporter activity
KM417_07280	COG1757	Na H antiporter
KM417_07295	COG4758	membrane
KM417_07300	COG4585	Histidine kinase
KM417_07305	COG2197	response regulator
KM417_07315	COG1114	Component of the transport system for branched-chain amino acids
KM417_07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM417_07350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM417_07350	COG1017	nitric oxide dioxygenase activity
KM417_07365	COG0730	response to heat
KM417_07370	COG0306	phosphate transporter
KM417_07375	COG1392	Phosphate transport regulator
KM417_07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_07395	COG3852	Histidine kinase
KM417_07400	COG1801	Protein of unknown function DUF72
KM417_07410	COG0582	viral genome integration into host DNA
KM417_07415	COG5002	protein histidine kinase activity
KM417_07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM417_07435	COG0392	lysyltransferase activity
KM417_07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_07455	COG1686	Belongs to the peptidase S11 family
KM417_07460	COG2715	membrane protein required for spore maturation
KM417_07465	COG0700	Nucleoside recognition
KM417_07470	COG1187	pseudouridine synthase activity
KM417_07480	COG1333	cytochrome c biogenesis protein
KM417_07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM417_07490	COG0745	RESPONSE REGULATOR receiver
KM417_07495	COG5002	protein histidine kinase activity
KM417_07500	COG2096	Adenosyltransferase
KM417_07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM417_07520	COG1141	Ferredoxin
KM417_07525	COG4955	Helix-turn-helix domain
KM417_07530	COG0514	ATP-dependent DNA helicase (RecQ)
KM417_07535	COG1266	CAAX protease self-immunity
KM417_07555	COG4862	establishment of competence for transformation
KM417_07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM417_07580	COG0492	ferredoxin-NADP+ reductase activity
KM417_07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_07670	COG0142	geranyltranstransferase activity
KM417_07680	COG0142	geranyltranstransferase activity
KM417_07700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM417_07705	COG0457	Tetratricopeptide repeat
KM417_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM417_07735	COG4347	Protein of unknown function (DUF1405)
KM417_07750	COG2738	Putative neutral zinc metallopeptidase
KM417_07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_07765	COG1694	Mazg nucleotide pyrophosphohydrolase
KM417_07780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_07785	COG0438	transferase activity, transferring glycosyl groups
KM417_07820	COG1199	ATP-dependent helicase activity
KM417_07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM417_07840	COG3935	DnaD domain protein
KM417_07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM417_07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM417_07915	COG0116	Belongs to the methyltransferase superfamily
KM417_07925	COG1199	ATP-dependent helicase activity
KM417_07930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM417_07940	COG3173	Aminoglycoside phosphotransferase
KM417_07945	COG0024	Methionine aminopeptidase
KM417_07955	COG2233	PERMEase
KM417_07960	COG2311	Membrane
KM417_07965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_07975	COG0456	acetyltransferase
KM417_08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_08050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM417_08065	COG1215	transferase activity, transferring glycosyl groups
KM417_08070	COG0438	transferase activity, transferring glycosyl groups
KM417_08085	COG0454	-acetyltransferase
KM417_08105	COG0328	RNA-DNA hybrid ribonuclease activity
KM417_08145	COG1280	lysine exporter protein (LysE YggA)
KM417_08160	COG3162	membrane
KM417_08165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_08170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_08180	COG0475	glutathione-regulated potassium exporter activity
KM417_08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_08190	COG0789	Transcriptional regulator
KM417_08190	COG4978	Transcriptional regulator
KM417_08200	COG2323	membrane
KM417_08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM417_08260	COG1923	regulation of RNA biosynthetic process
KM417_08270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM417_08275	COG1360	Flagellar Motor Protein
KM417_08280	COG2201	protein-glutamate methylesterase activity
KM417_08285	COG0643	Histidine kinase
KM417_08285	COG2198	Histidine kinase
KM417_08290	COG2198	Histidine kinase
KM417_08290	COG0643	Histidine kinase
KM417_08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_08295	COG1776	CheC inhibitor of MCP methylation
KM417_08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM417_08330	COG1256	bacterial-type flagellum assembly
KM417_08355	COG1815	bacterial-type flagellum-dependent cell motility
KM417_08360	COG1558	bacterial-type flagellum-dependent cell motility
KM417_08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_08385	COG1157	protein secretion by the type III secretion system
KM417_08425	COG0784	Response regulator, receiver
KM417_08425	COG0835	chemotaxis
KM417_08435	COG0463	Glycosyl transferase, family 2
KM417_08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM417_08475	COG0741	lytic transglycosylase activity
KM417_08490	COG1776	CheC inhibitor of MCP methylation
KM417_08490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM417_08500	COG1338	Plays a role in the flagellum-specific transport system
KM417_08505	COG1987	bacterial-type flagellum assembly
KM417_08515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM417_08520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM417_08525	COG1419	protein localization to endoplasmic reticulum
KM417_08530	COG4786	Flagellar basal body rod
KM417_08535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_08560	COG1309	transcriptional regulator
KM417_08580	COG2329	Antibiotic biosynthesis monooxygenase
KM417_08605	COG0583	DNA-binding transcription factor activity
KM417_08610	COG3842	ATPase activity
KM417_08615	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM417_08625	COG1234	tRNA 3'-trailer cleavage
KM417_08650	COG1686	Belongs to the peptidase S11 family
KM417_08660	COG0406	alpha-ribazole phosphatase activity
KM417_08690	COG0367	asparagine synthase
KM417_08720	COG1802	Transcriptional regulator
KM417_08725	COG0697	spore germination
KM417_08730	COG0523	cobalamin synthesis protein
KM417_08735	COG0701	Predicted permease
KM417_08745	COG1216	Glycosyl transferase, family 2
KM417_08745	COG0438	transferase activity, transferring glycosyl groups
KM417_08750	COG1757	Na H antiporter
KM417_08755	COG0114	fumarate hydratase activity
KM417_08780	COG3340	Belongs to the peptidase S51 family
KM417_08800	COG0785	Cytochrome C biogenesis protein
KM417_08830	COG2733	membrane
KM417_08865	COG1131	(ABC) transporter
KM417_08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_08885	COG0528	UMP kinase activity
KM417_08895	COG1027	Aspartate ammonia-lyase
KM417_08900	COG0281	malic enzyme
KM417_08905	COG4191	Histidine kinase
KM417_08910	COG0784	Response regulator, receiver
KM417_08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_08970	COG1051	belongs to the nudix hydrolase family
KM417_08975	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_08985	COG2814	Major facilitator Superfamily
KM417_09000	COG1966	Carbon starvation protein
KM417_09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM417_09035	COG2223	nitrite transmembrane transporter activity
KM417_09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_09055	COG2244	polysaccharide biosynthetic process
KM417_09060	COG0733	neurotransmitter:sodium symporter activity
KM417_09070	COG5566	PFAM Mor transcription activator
KM417_09075	COG2323	membrane
KM417_09090	COG2084	Dehydrogenase
KM417_09105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_09120	COG0028	Belongs to the TPP enzyme family
KM417_09125	COG0440	acetolactate synthase activity
KM417_09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM417_09140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM417_09165	COG2814	Major facilitator Superfamily
KM417_09170	COG3384	dioxygenase
KM417_09180	COG3279	Response regulator of the LytR AlgR family
KM417_09185	COG0427	acetyl-CoA hydrolase
KM417_09205	COG1073	alpha beta
KM417_09235	COG0535	radical SAM domain protein
KM417_09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_09260	COG1914	H( )-stimulated, divalent metal cation uptake system
KM417_09275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM417_09305	COG2390	Transcriptional regulator
KM417_09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM417_09335	COG4224	UPF0291 protein
KM417_09355	COG0006	proline dipeptidase activity
KM417_09360	COG2132	Multicopper oxidase
KM417_09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM417_09390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_09405	COG2372	response to copper ion
KM417_09405	COG1276	copper resistance
KM417_09410	COG4549	nuclear export factor GLE1
KM417_09420	COG0697	spore germination
KM417_09425	COG0583	DNA-binding transcription factor activity
KM417_09430	COG1959	2 iron, 2 sulfur cluster binding
KM417_09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM417_09440	COG0778	Nitroreductase
KM417_09450	COG0628	permease
KM417_09460	COG1231	oxidoreductase activity
KM417_09465	COG0523	cobalamin synthesis protein
KM417_09480	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_09485	COG2030	dehydratase
KM417_09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_09500	COG0411	ABC transporter
KM417_09520	COG0583	DNA-binding transcription factor activity
KM417_09540	COG1846	Transcriptional regulator
KM417_09550	COG1271	oxidase subunit
KM417_09555	COG1294	oxidase, subunit
KM417_09560	COG4988	ABC transporter
KM417_09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM417_09585	COG1686	Belongs to the peptidase S11 family
KM417_09600	COG0791	NLP P60 protein
KM417_09600	COG1388	LysM domain
KM417_09615	COG0745	RESPONSE REGULATOR receiver
KM417_09620	COG5002	protein histidine kinase activity
KM417_09630	COG0300	oxidoreductase activity
KM417_09665	COG0460	homoserine dehydrogenase
KM417_09690	COG1316	TRANSCRIPTIONal
KM417_09700	COG0745	RESPONSE REGULATOR receiver
KM417_09705	COG5002	protein histidine kinase activity
KM417_09720	COG1285	pathogenesis
KM417_09725	COG1247	-acetyltransferase
KM417_09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_09755	COG1082	Xylose isomerase domain protein TIM barrel
KM417_09770	COG1279	arginine transmembrane transporter activity
KM417_09780	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM417_09820	COG2002	toxin-antitoxin pair type II binding
KM417_09825	COG1404	Belongs to the peptidase S8 family
KM417_09830	COG0640	Transcriptional regulator
KM417_09835	COG0667	Aldo Keto reductase
KM417_09840	COG2814	Major facilitator Superfamily
KM417_09865	COG0840	transmembrane signaling receptor activity
KM417_09880	COG3949	Membrane
KM417_09885	COG0783	Belongs to the Dps family
KM417_09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_09910	COG1231	oxidoreductase activity
KM417_09920	COG4989	oxidoreductase activity
KM417_09925	COG0523	cobalamin synthesis protein
KM417_09930	COG0456	acetyltransferase
KM417_09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM417_09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM417_09995	COG0702	epimerase
KM417_10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM417_10015	COG4166	transmembrane transport
KM417_10030	COG0406	alpha-ribazole phosphatase activity
KM417_10040	COG5337	Spore coat protein CotH
KM417_10045	COG1051	belongs to the nudix hydrolase family
KM417_10050	COG0586	Pfam SNARE associated Golgi protein
KM417_10055	COG2244	polysaccharide biosynthetic process
KM417_10065	COG0701	Predicted permease
KM417_10070	COG3689	TIGRFAM TIGR03943 family protein
KM417_10075	COG1607	acyl-coa hydrolase
KM417_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_10100	COG0702	epimerase
KM417_10105	COG2839	Protein conserved in bacteria
KM417_10110	COG1253	flavin adenine dinucleotide binding
KM417_10125	COG1114	Component of the transport system for branched-chain amino acids
KM417_10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_10160	COG1876	peptidase activity
KM417_10170	COG0154	amidase activity
KM417_10175	COG2211	Major facilitator Superfamily
KM417_10195	COG0561	phosphatase activity
KM417_10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM417_10210	COG4106	trans-aconitate 2-methyltransferase activity
KM417_10225	COG1819	glycosyl
KM417_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_10260	COG0456	acetyltransferase
KM417_10310	COG3874	Sporulation protein YtfJ
KM417_10335	COG2226	methyltransferase
KM417_10360	COG0346	lactoylglutathione lyase activity
KM417_10370	COG0604	alcohol dehydrogenase
KM417_10375	COG1595	DNA-templated transcription, initiation
KM417_10400	COG0386	Belongs to the glutathione peroxidase family
KM417_10405	COG1305	Transglutaminase-like
KM417_10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM417_10415	COG0714	Associated with various cellular activities
KM417_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM417_10435	COG1140	nitrate reductase beta subunit
KM417_10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM417_10445	COG2181	nitrate reductase activity
KM417_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM417_10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM417_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_10480	COG0303	'Molybdopterin
KM417_10485	COG0314	molybdopterin synthase activity
KM417_10495	COG2223	nitrite transmembrane transporter activity
KM417_10510	COG1648	precorrin-2 dehydrogenase activity
KM417_10520	COG1587	Uroporphyrinogen-III synthase
KM417_10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM417_10525	COG2146	nitrite reductase [NAD(P)H] activity
KM417_10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM417_10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM417_10570	COG2359	stage V sporulation protein S
KM417_10585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM417_10600	COG1418	mRNA catabolic process
KM417_10605	COG0488	(ABC) transporter
KM417_10620	COG0629	single-stranded DNA binding
KM417_10635	COG1413	lyase activity
KM417_10650	COG2521	methyltransferase
KM417_10650	COG2136	Putative SAM-dependent methyltransferase
KM417_10655	COG0018	arginyl-trna synthetase
KM417_10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM417_10700	COG0017	Asparaginyl-tRNA synthetase
KM417_10720	COG1674	ftsk spoiiie
KM417_10790	COG1929	Belongs to the glycerate kinase type-1 family
KM417_10795	COG0471	metal ion transport
KM417_10800	COG0745	RESPONSE REGULATOR receiver
KM417_10805	COG3850	Histidine kinase
KM417_10805	COG5002	protein histidine kinase activity
KM417_10820	COG0733	neurotransmitter:sodium symporter activity
KM417_10845	COG2610	gluconate transmembrane transporter activity
KM417_10850	COG1454	alcohol dehydrogenase
KM417_10855	COG1794	racemase activity, acting on amino acids and derivatives
KM417_10865	COG0456	acetyltransferase
KM417_10880	COG1131	(ABC) transporter
KM417_10895	COG0546	phosphoglycolate phosphatase activity
KM417_10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_10930	COG0768	penicillin binding
KM417_10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM417_10940	COG0204	Acyl-transferase
KM417_10945	COG1272	protein, Hemolysin III
KM417_10955	COG0805	protein transport
KM417_10965	COG1307	EDD domain protein, DegV family
KM417_10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM417_10975	COG1999	signal sequence binding
KM417_10980	COG0071	Belongs to the small heat shock protein (HSP20) family
KM417_10985	COG0367	asparagine synthase
KM417_11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM417_11030	COG1051	belongs to the nudix hydrolase family
KM417_11040	COG0668	transmembrane transport
KM417_11045	COG2203	Gaf domain
KM417_11045	COG4585	Histidine kinase
KM417_11050	COG2197	response regulator
KM417_11060	COG1064	alcohol dehydrogenase
KM417_11085	COG1070	Carbohydrate kinase
KM417_11090	COG1070	Carbohydrate kinase
KM417_11120	COG0517	IMP dehydrogenase activity
KM417_11120	COG1125	glycine betaine transport
KM417_11125	COG1174	glycine betaine transport
KM417_11160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM417_11170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM417_11175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM417_11180	COG0456	acetyltransferase
KM417_11185	COG3829	transcription factor binding
KM417_11190	COG1509	lysine 2,3-aminomutase activity
KM417_11230	COG4326	sporulation control protein
KM417_11235	COG0671	phosphoesterase, PA-phosphatase related
KM417_11240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM417_11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_11275	COG1715	Restriction endonuclease
KM417_11275	COG1787	Restriction endonuclease
KM417_11365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM417_11405	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM417_11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_11410	COG2814	Major facilitator Superfamily
KM417_11415	COG4841	protein insertion into membrane
KM417_11420	COG0372	Belongs to the citrate synthase family
KM417_11425	COG2079	MmgE PrpD family protein
KM417_11430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM417_11435	COG1960	acyl-CoA dehydrogenase activity
KM417_11440	COG2084	Dehydrogenase
KM417_11450	COG1280	lysine exporter protein (LysE YggA)
KM417_11455	COG1024	Enoyl-CoA hydratase
KM417_11470	COG0420	3'-5' exonuclease activity
KM417_11475	COG0419	ATPase involved in DNA repair
KM417_11495	COG2223	nitrite transmembrane transporter activity
KM417_11500	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_11505	COG1169	isochorismate synthase
KM417_11510	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM417_11515	COG3433	isochorismatase activity
KM417_11515	COG1535	isochorismatase
KM417_11520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM417_11525	COG3251	PFAM MbtH domain protein
KM417_11530	COG2814	Major facilitator Superfamily
KM417_11545	COG0776	regulation of translation
KM417_11555	COG2318	DinB family
KM417_11565	COG1115	amino acid carrier protein
KM417_11580	COG2329	Antibiotic biosynthesis monooxygenase
KM417_11585	COG1187	pseudouridine synthase activity
KM417_11590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_11605	COG0596	Alpha beta hydrolase
KM417_11610	COG2814	Major facilitator Superfamily
KM417_11630	COG2226	methyltransferase
KM417_11675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_11710	COG1247	-acetyltransferase
KM417_11740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM417_11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_11760	COG1278	Cold shock
KM417_11775	COG0010	Belongs to the arginase family
KM417_11780	COG0561	phosphatase activity
KM417_11825	COG0583	DNA-binding transcription factor activity
KM417_11830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM417_11845	COG0583	DNA-binding transcription factor activity
KM417_11850	COG2258	MOSC domain
KM417_11865	COG1132	(ABC) transporter
KM417_11870	COG1132	(ABC) transporter
KM417_11890	COG1396	sequence-specific DNA binding
KM417_11915	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM417_11920	COG1595	DNA-templated transcription, initiation
KM417_11945	COG1649	PFAM Uncharacterised BCR, COG1649
KM417_11970	COG2971	BadF BadG BcrA BcrD
KM417_11975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_11980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM417_12000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_12030	COG1309	transcriptional regulator
KM417_12045	COG1136	(ABC) transporter
KM417_12045	COG0577	efflux transmembrane transporter activity
KM417_12050	COG0500	methyltransferase
KM417_12050	COG3615	Tellurite resistance protein tehB
KM417_12060	COG2226	methyltransferase
KM417_12065	COG3961	Belongs to the TPP enzyme family
KM417_12070	COG1846	Transcriptional regulator
KM417_12110	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM417_12125	COG1595	DNA-templated transcription, initiation
KM417_12135	COG0768	penicillin binding
KM417_12145	COG2367	Beta-lactamase
KM417_12150	COG0671	phosphoesterase, PA-phosphatase related
KM417_12155	COG1609	Transcriptional regulator
KM417_12160	COG2814	Major facilitator Superfamily
KM417_12165	COG0673	inositol 2-dehydrogenase activity
KM417_12175	COG1012	belongs to the aldehyde dehydrogenase family
KM417_12190	COG0191	fructose-bisphosphate aldolase activity
KM417_12195	COG3718	enzyme involved in inositol metabolism
KM417_12220	COG0457	Tetratricopeptide repeat
KM417_12225	COG1476	TRANSCRIPTIONal
KM417_12240	COG1876	peptidase activity
KM417_12260	COG1309	transcriptional regulator
KM417_12265	COG0488	(ABC) transporter
KM417_12280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_12295	COG1252	NADH dehydrogenase
KM417_12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_12315	COG1131	(ABC) transporter
KM417_12325	COG1309	transcriptional regulator
KM417_12340	COG1960	acyl-CoA dehydrogenase activity
KM417_12345	COG0439	Biotin carboxylase
KM417_12350	COG0511	ligase activity, forming carbon-carbon bonds
KM417_12355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM417_12360	COG1024	Enoyl-CoA hydratase
KM417_12365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM417_12370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_12380	COG1247	-acetyltransferase
KM417_12385	COG0572	uridine kinase
KM417_12395	COG2318	DinB family
KM417_12400	COG1686	Belongs to the peptidase S11 family
KM417_12425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM417_12465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_12465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_12490	COG2814	Major facilitator Superfamily
KM417_12510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_12530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_12545	COG1063	alcohol dehydrogenase
KM417_12575	COG3773	Cell wall hydrolase
KM417_12585	COG0745	RESPONSE REGULATOR receiver
KM417_12600	COG0488	(ABC) transporter
KM417_12615	COG1136	(ABC) transporter
KM417_12640	COG0460	homoserine dehydrogenase
KM417_12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_12655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM417_12720	COG2124	cytochrome p450
KM417_12755	COG0561	phosphatase activity
KM417_12765	COG5002	protein histidine kinase activity
KM417_12770	COG0768	penicillin binding
KM417_12775	COG1819	glycosyl
KM417_12780	COG1794	racemase activity, acting on amino acids and derivatives
KM417_12790	COG1122	ATPase activity
KM417_12805	COG2205	protein histidine kinase activity
KM417_12815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_12820	COG0604	alcohol dehydrogenase
KM417_12825	COG0768	penicillin binding
KM417_12835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_12870	COG0693	protein deglycase activity
KM417_12900	COG2814	Major facilitator Superfamily
KM417_12915	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_12935	COG0697	spore germination
KM417_12960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_12970	COG2223	nitrite transmembrane transporter activity
KM417_12985	COG2816	NAD+ diphosphatase activity
KM417_12990	COG0592	DNA-directed DNA polymerase activity
KM417_12995	COG1051	belongs to the nudix hydrolase family
KM417_13030	COG3878	Protein conserved in bacteria
KM417_13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM417_13090	COG0322	excinuclease ABC activity
KM417_13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_13155	COG1011	Hydrolase
KM417_13175	COG0076	glutamate decarboxylase activity
KM417_13190	COG1523	belongs to the glycosyl hydrolase 13 family
KM417_13195	COG3227	Zinc metalloprotease (Elastase)
KM417_13215	COG0201	protein transport
KM417_13225	COG0697	spore germination
KM417_13230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_13260	COG4129	membrane
KM417_13265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_13280	COG2959	enzyme of heme biosynthesis
KM417_13300	COG3483	tryptophan 2,3-dioxygenase activity
KM417_13305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM417_13310	COG3844	kynureninase activity
KM417_13315	COG1309	transcriptional regulator
KM417_13345	COG3284	Transcriptional regulator
KM417_13365	COG1349	DNA-binding transcription factor activity
KM417_13385	COG1959	2 iron, 2 sulfur cluster binding
KM417_13400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM417_13405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_13410	COG0022	dehydrogenase e1 component
KM417_13415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_13425	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_13430	COG0456	acetyltransferase
KM417_13430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_13460	COG4176	ABC-type proline glycine betaine transport system permease component
KM417_13465	COG0517	IMP dehydrogenase activity
KM417_13465	COG4175	Glycine betaine
KM417_13490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM417_13495	COG2153	protein acetylation
KM417_13500	COG3397	chitin binding
KM417_13515	COG2205	protein histidine kinase activity
KM417_13540	COG0658	competence protein
KM417_13540	COG2333	competence protein COMEC
KM417_13590	COG3973	AAA domain
KM417_13605	COG2105	PFAM AIG2 family protein
KM417_13610	COG0514	ATP-dependent DNA helicase (RecQ)
KM417_13630	COG4637	Psort location Cytoplasmic, score
KM417_13655	COG3397	chitin binding
KM417_13670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM417_13675	COG1115	amino acid carrier protein
KM417_13680	COG1012	belongs to the aldehyde dehydrogenase family
KM417_13685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM417_13695	COG3938	Belongs to the proline racemase family
KM417_13700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM417_13740	COG0586	Pfam SNARE associated Golgi protein
KM417_13755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM417_13760	COG0519	Catalyzes the synthesis of GMP from XMP
KM417_13765	COG4166	transmembrane transport
KM417_13775	COG4948	Mandelate Racemase Muconate Lactonizing
KM417_13820	COG2936	dipeptidyl-peptidase activity
KM417_13825	COG5002	protein histidine kinase activity
KM417_13865	COG1164	Oligoendopeptidase f
KM417_13880	COG1307	EDD domain protein, DegV family
KM417_13900	COG2814	Major facilitator Superfamily
KM417_13910	COG1664	Polymer-forming cytoskeletal
KM417_13915	COG0789	Transcriptional regulator
KM417_13920	COG4533	DNA binding
KM417_13925	COG0477	Major facilitator Superfamily
KM417_13925	COG2814	Major facilitator Superfamily
KM417_13945	COG2261	transglycosylase associated protein
KM417_13960	COG2226	methyltransferase
KM417_13995	COG0436	Aminotransferase
KM417_14000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM417_14005	COG5146	pantothenate kinase activity
KM417_14025	COG1131	(ABC) transporter
KM417_14070	COG0628	permease
KM417_14080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_14085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_14090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_14095	COG1116	anion transmembrane transporter activity
KM417_14115	COG2816	NAD+ diphosphatase activity
KM417_14135	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM417_14160	COG0697	spore germination
KM417_14165	COG2318	DinB family
KM417_14185	COG4912	Dna alkylation repair
KM417_14205	COG0861	Integral membrane protein TerC family
KM417_14210	COG1368	sulfuric ester hydrolase activity
KM417_14215	COG0488	(ABC) transporter
KM417_14225	COG1033	growth of symbiont in host cell
KM417_14225	COG2409	Drug exporters of the RND superfamily
KM417_14230	COG1033	growth of symbiont in host cell
KM417_14230	COG2409	Drug exporters of the RND superfamily
KM417_14235	COG1033	growth of symbiont in host cell
KM417_14235	COG2409	Drug exporters of the RND superfamily
KM417_14240	COG1309	transcriptional regulator
KM417_14255	COG0287	Prephenate dehydrogenase
KM417_14260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM417_14265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM417_14270	COG1605	Chorismate mutase
KM417_14270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM417_14305	COG3584	3D domain protein
KM417_14305	COG1388	LysM domain
KM417_14315	COG1595	DNA-templated transcription, initiation
KM417_14340	COG1879	ABC-type sugar transport system periplasmic component
KM417_14350	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM417_14360	COG2390	Transcriptional regulator
KM417_14395	COG2329	Antibiotic biosynthesis monooxygenase
KM417_14415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_14425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM417_14430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_14435	COG4187	Peptidase family M20/M25/M40
KM417_14440	COG1414	Transcriptional regulator
KM417_14445	COG0833	amino acid
KM417_14450	COG1690	Belongs to the RtcB family
KM417_14455	COG3239	Fatty acid desaturase
KM417_14460	COG1785	Belongs to the alkaline phosphatase family
KM417_14470	COG3655	Transcriptional regulator
KM417_14485	COG4377	Putative membrane peptidase family (DUF2324)
KM417_14495	COG3279	Response regulator of the LytR AlgR family
KM417_14505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_14510	COG0346	lactoylglutathione lyase activity
KM417_14530	COG0714	Associated with various cellular activities
KM417_14555	COG0463	Glycosyl transferase, family 2
KM417_14580	COG0463	Glycosyl transferase, family 2
KM417_14590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM417_14595	COG0753	catalase activity
KM417_14605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM417_14630	COG0714	Associated with various cellular activities
KM417_14640	COG0778	Nitroreductase
KM417_14645	COG1846	Transcriptional regulator
KM417_14680	COG1725	Transcriptional regulator
KM417_14690	COG0577	efflux transmembrane transporter activity
KM417_14690	COG1136	(ABC) transporter
KM417_14715	COG2207	Transcriptional regulator
KM417_14720	COG0456	acetyltransferase
KM417_14740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_14760	COG0642	Histidine kinase
KM417_14765	COG0745	RESPONSE REGULATOR receiver
KM417_14770	COG0596	Alpha beta hydrolase
KM417_14800	COG0730	response to heat
KM417_14810	COG0833	amino acid
KM417_14820	COG4335	DNA alkylation repair
KM417_14860	COG0768	penicillin binding
KM417_14870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM417_14900	COG1984	allophanate hydrolase subunit 2
KM417_14905	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM417_14910	COG1414	Transcriptional regulator
KM417_14925	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM417_14930	COG0640	Transcriptional regulator
KM417_14940	COG1960	acyl-CoA dehydrogenase activity
KM417_14955	COG3314	Sporulation integral membrane protein YlbJ
KM417_14970	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM417_14985	COG0574	Belongs to the PEP-utilizing enzyme family
KM417_14985	COG3848	Pyruvate phosphate dikinase
KM417_14990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_15005	COG5577	PFAM Coat F domain
KM417_15010	COG3403	YqcI/YcgG family
KM417_15015	COG1280	lysine exporter protein (LysE YggA)
KM417_15050	COG1063	alcohol dehydrogenase
KM417_15065	COG1027	Aspartate ammonia-lyase
KM417_15070	COG0252	asparaginase activity
KM417_15075	COG1396	sequence-specific DNA binding
KM417_15085	COG0322	excinuclease ABC activity
KM417_15090	COG0531	amino acid
KM417_15095	COG1114	Component of the transport system for branched-chain amino acids
KM417_15100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_15110	COG0281	malic enzyme
KM417_15125	COG0531	amino acid
KM417_15135	COG0784	Response regulator, receiver
KM417_15145	COG2066	Belongs to the glutaminase family
KM417_15150	COG1115	amino acid carrier protein
KM417_15180	COG0737	Belongs to the 5'-nucleotidase family
KM417_15185	COG0753	catalase activity
KM417_15190	COG2267	carboxylic ester hydrolase activity
KM417_15195	COG1335	isochorismatase
KM417_15215	COG0583	DNA-binding transcription factor activity
KM417_15220	COG1846	Transcriptional regulator
KM417_15260	COG0415	Belongs to the DNA photolyase family
KM417_15265	COG0288	reversible hydration of carbon dioxide
KM417_15275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM417_15280	COG5609	conserved protein (DUF2294)
KM417_15295	COG1575	Belongs to the MenA family. Type 1 subfamily
KM417_15300	COG2267	carboxylic ester hydrolase activity
KM417_15305	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM417_15310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM417_15315	COG1121	(ABC) transporter
KM417_15345	COG0798	PFAM Bile acid sodium symporter
KM417_15350	COG0346	lactoylglutathione lyase activity
KM417_15355	COG0640	Transcriptional regulator
KM417_15370	COG0443	Heat shock 70 kDa protein
KM417_15385	COG1522	sequence-specific DNA binding
KM417_15400	COG0346	lactoylglutathione lyase activity
KM417_15425	COG2169	Transcriptional regulator
KM417_15470	COG2814	Major facilitator Superfamily
KM417_15495	COG0745	RESPONSE REGULATOR receiver
KM417_15500	COG3850	Histidine kinase
KM417_15500	COG5002	protein histidine kinase activity
KM417_15525	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM417_15545	COG1476	TRANSCRIPTIONal
KM417_15560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM417_15575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_15580	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM417_15595	COG1136	(ABC) transporter
KM417_15600	COG0577	efflux transmembrane transporter activity
KM417_15615	COG3850	Histidine kinase
KM417_15615	COG5002	protein histidine kinase activity
KM417_15625	COG2364	Membrane
KM417_15630	COG1846	Transcriptional regulator
KM417_15640	COG2808	Putative FMN-binding domain
KM417_15645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_15650	COG2271	Major facilitator Superfamily
KM417_15655	COG1556	Lactate utilization protein
KM417_15660	COG1139	Iron-sulfur cluster binding protein
KM417_15670	COG0583	DNA-binding transcription factor activity
KM417_15680	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_15700	COG0738	Major facilitator superfamily
KM417_15705	COG0673	inositol 2-dehydrogenase activity
KM417_15710	COG0561	phosphatase activity
KM417_15720	COG1609	Transcriptional regulator
KM417_15725	COG0457	Tetratricopeptide repeat
KM417_15745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_15775	COG0534	Mate efflux family protein
KM417_15795	COG2814	Major facilitator Superfamily
KM417_15800	COG1309	transcriptional regulator
KM417_15815	COG0814	amino acid
KM417_15820	COG1760	l-serine dehydratase
KM417_15825	COG1760	l-serine dehydratase
KM417_15835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM417_15840	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM417_15850	COG1335	isochorismatase
KM417_15855	COG1522	sequence-specific DNA binding
KM417_15860	COG0531	amino acid
KM417_15875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM417_15895	COG1595	DNA-templated transcription, initiation
KM417_15910	COG0662	Cupin 2, conserved barrel domain protein
KM417_15915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_15915	COG2207	Transcriptional regulator
KM417_15965	COG0477	Major facilitator Superfamily
KM417_15975	COG1846	Transcriptional regulator
KM417_15980	COG2814	Major facilitator Superfamily
KM417_15990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_15995	COG1131	(ABC) transporter
KM417_16015	COG2076	Multidrug Resistance protein
KM417_16020	COG1309	transcriptional regulator
KM417_16030	COG2031	fatty acid transporter
KM417_16040	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_16070	COG1122	ATPase activity
KM417_16075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM417_16090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM417_16095	COG1288	antiporter activity
KM417_16100	COG2356	endonuclease I
KM417_16115	COG3620	sequence-specific DNA binding
KM417_16120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_16125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM417_16130	COG0124	histidyl-tRNA synthetase
KM417_16145	COG1733	regulation of RNA biosynthetic process
KM417_16150	COG0778	Nitroreductase
KM417_16170	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_16180	COG1131	(ABC) transporter
KM417_16205	COG1011	Hydrolase
KM417_16215	COG2365	Tyrosine phosphatase family
KM417_16240	COG0346	lactoylglutathione lyase activity
KM417_16245	COG1940	carbohydrate kinase activity
KM417_16250	COG0738	Major facilitator superfamily
KM417_16255	COG0110	maltose O-acetyltransferase activity
KM417_16265	COG1136	(ABC) transporter
KM417_16265	COG0577	efflux transmembrane transporter activity
KM417_16280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM417_16285	COG0628	permease
KM417_16305	COG2226	methyltransferase
KM417_16315	COG0477	Major facilitator Superfamily
KM417_16345	COG1253	flavin adenine dinucleotide binding
KM417_16350	COG0789	Transcriptional regulator
KM417_16355	COG0697	spore germination
KM417_16360	COG1357	PFAM Pentapeptide repeats (8 copies)
KM417_16365	COG3813	Protein conserved in bacteria
KM417_16370	COG2706	6-phosphogluconolactonase activity
KM417_16375	COG1070	Carbohydrate kinase
KM417_16385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM417_16390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM417_16400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM417_16405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM417_16410	COG0604	alcohol dehydrogenase
KM417_16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM417_16425	COG3321	synthase
KM417_16425	COG0604	alcohol dehydrogenase
KM417_16430	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_16455	COG0656	L-ascorbic acid biosynthetic process
KM417_16460	COG2814	Major facilitator Superfamily
KM417_16475	COG0346	lactoylglutathione lyase activity
KM417_16480	COG0814	amino acid
KM417_16505	COG1393	Belongs to the ArsC family
KM417_16510	COG1733	regulation of RNA biosynthetic process
KM417_16515	COG2188	Transcriptional regulator
KM417_16525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM417_16530	COG1733	regulation of RNA biosynthetic process
KM417_16535	COG1733	regulation of RNA biosynthetic process
KM417_16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_16570	COG0384	phenazine biosynthesis protein PhzF
KM417_16580	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_16590	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_16600	COG1733	regulation of RNA biosynthetic process
KM417_16635	COG1191	sigma factor activity
KM417_16650	COG1309	transcriptional regulator
KM417_16670	COG3152	Membrane
KM417_16695	COG1151	hydroxylamine reductase activity
KM417_16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_16710	COG3757	hydrolase, family 25
KM417_16710	COG3409	Peptidoglycan-binding domain 1 protein
KM417_16745	COG2072	flavoprotein involved in K transport
KM417_16780	COG0604	alcohol dehydrogenase
KM417_16785	COG1113	amino acid transport
KM417_16790	COG2814	Major facilitator Superfamily
KM417_16820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_16825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_16845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_16850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_16855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_16860	COG3739	integral membrane protein
KM417_16865	COG0384	phenazine biosynthesis protein PhzF
KM417_16895	COG0583	DNA-binding transcription factor activity
KM417_16915	COG1193	negative regulation of DNA recombination
KM417_16940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM417_16970	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_16995	COG0640	Transcriptional regulator
KM417_17000	COG0604	alcohol dehydrogenase
KM417_17020	COG2808	Putative FMN-binding domain
KM417_17025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_17035	COG0385	Bile acid
KM417_17040	COG0277	FAD linked oxidase domain protein
KM417_17070	COG1216	Glycosyl transferase, family 2
KM417_17075	COG1024	Enoyl-CoA hydratase
KM417_17085	COG1285	pathogenesis
KM417_17100	COG2514	catechol 2,3-dioxygenase activity
KM417_17105	COG2720	vancomycin resistance protein
KM417_17145	COG0716	FMN binding
KM417_17175	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_17185	COG0165	Argininosuccinate lyase
KM417_17200	COG4145	pantothenate transmembrane transporter activity
KM417_17210	COG1012	belongs to the aldehyde dehydrogenase family
KM417_17215	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_17225	COG1657	PFAM Prenyltransferase squalene oxidase
KM417_17230	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM417_17235	COG2962	Rard protein
KM417_17240	COG3326	Membrane
KM417_17255	COG0489	protein tyrosine kinase activity
KM417_17265	COG0314	molybdopterin synthase activity
KM417_17270	COG0303	'Molybdopterin
KM417_17275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_17280	COG2116	formate transmembrane transporter activity
KM417_17290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM417_17295	COG5609	conserved protein (DUF2294)
KM417_17300	COG2427	Protein of unknown function (DUF1641)
KM417_17305	COG3383	formate dehydrogenase (NAD+) activity
KM417_17310	COG0697	spore germination
KM417_17350	COG2226	methyltransferase
KM417_17355	COG4166	transmembrane transport
KM417_17360	COG4166	transmembrane transport
KM417_17365	COG4166	transmembrane transport
KM417_17370	COG1301	dicarboxylic acid transport
KM417_17375	COG1316	TRANSCRIPTIONal
KM417_17385	COG1595	DNA-templated transcription, initiation
KM417_17405	COG1131	(ABC) transporter
KM417_17415	COG0673	inositol 2-dehydrogenase activity
KM417_17420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM417_17425	COG0187	DNA topoisomerase II activity
KM417_17430	COG1832	CoA-binding protein
KM417_17435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_17440	COG0745	RESPONSE REGULATOR receiver
KM417_17455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM417_17460	COG4841	protein insertion into membrane
KM417_17465	COG0824	Thioesterase
KM417_17495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_17505	COG2274	protein secretion by the type I secretion system
KM417_17510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM417_17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_17565	COG0183	Belongs to the thiolase family
KM417_17570	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_17575	COG1268	BioY protein
KM417_17580	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_17630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_17640	COG5002	protein histidine kinase activity
KM417_17645	COG0400	carboxylic ester hydrolase activity
KM417_17650	COG0346	lactoylglutathione lyase activity
KM417_17655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM417_17660	COG0069	glutamate synthase activity
KM417_17665	COG1902	pentaerythritol trinitrate reductase activity
KM417_17670	COG1329	Transcriptional regulator
KM417_17675	COG0010	Belongs to the arginase family
KM417_17700	COG2226	methyltransferase
KM417_17755	COG4846	Membrane protein involved in cytochrome C biogenesis
KM417_17760	COG0785	Cytochrome C biogenesis protein
KM417_17770	COG0583	DNA-binding transcription factor activity
KM417_17775	COG1380	Effector of murein hydrolase LrgA
KM417_17780	COG1346	cytolysis
KM417_17805	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM417_17805	COG3409	Peptidoglycan-binding domain 1 protein
KM417_17820	COG1132	(ABC) transporter
KM417_17825	COG1132	(ABC) transporter
KM417_17855	COG3639	organic phosphonate transmembrane transporter activity
KM417_17860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM417_17880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM417_17900	COG1695	Transcriptional regulator
KM417_17935	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM417_17935	COG3409	Peptidoglycan-binding domain 1 protein
KM417_17935	COG1388	LysM domain
KM417_17940	COG4824	toxin secretion phage lysis holin
KM417_18095	COG1595	DNA-templated transcription, initiation
KM417_18140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM417_18220	COG1396	sequence-specific DNA binding
KM417_18245	COG0174	glutamine synthetase
KM417_18250	COG0789	Transcriptional regulator
KM417_18255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM417_18265	COG2860	membrane
KM417_18275	COG0464	growth
KM417_18305	COG3584	3D domain protein
KM417_18305	COG1388	LysM domain
KM417_18310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM417_18310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_18310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM417_18315	COG1105	Belongs to the carbohydrate kinase PfkB family
KM417_18320	COG1349	DNA-binding transcription factor activity
KM417_18330	COG2322	membrane
KM417_18340	COG1113	amino acid transport
KM417_18355	COG1408	metallophosphoesterase
KM417_18360	COG2116	formate transmembrane transporter activity
KM417_18370	COG2217	Heavy metal translocating P-type atpase
KM417_18375	COG2608	mercury ion transmembrane transporter activity
KM417_18380	COG1937	Protein conserved in bacteria
KM417_18390	COG2819	hydrolase of the alpha beta superfamily
KM417_18395	COG1120	ATPase activity
KM417_18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_18415	COG0708	Exodeoxyribonuclease III
KM417_18420	COG2169	Transcriptional regulator
KM417_18425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM417_18430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM417_18440	COG2364	Membrane
KM417_18455	COG2267	carboxylic ester hydrolase activity
KM417_18460	COG0346	lactoylglutathione lyase activity
KM417_18465	COG5001	Diguanylate cyclase
KM417_18465	COG3300	MHYT domain
KM417_18480	COG1346	cytolysis
KM417_18485	COG1380	Effector of murein hydrolase LrgA
KM417_18490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM417_18495	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_18495	COG0596	Alpha beta hydrolase
KM417_18500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM417_18520	COG1404	Belongs to the peptidase S8 family
KM417_18525	COG3773	Cell wall hydrolase
KM417_18530	COG0562	UDP-galactopyranose mutase
KM417_18535	COG1368	sulfuric ester hydrolase activity
KM417_18540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM417_18550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM417_18575	COG1131	(ABC) transporter
KM417_18595	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM417_18600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM417_18605	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM417_18610	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM417_18610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM417_18620	COG2359	stage V sporulation protein S
KM417_18625	COG1692	metallophosphoesterase
KM417_18650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM417_18655	COG1426	Protein conserved in bacteria
KM417_18670	COG0300	oxidoreductase activity
KM417_18675	COG0612	Peptidase, M16
KM417_18680	COG0612	Peptidase, M16
KM417_18685	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM417_18695	COG3845	ABC transporter
KM417_18700	COG1744	ABC transporter substrate-binding protein PnrA-like
KM417_18705	COG2188	Transcriptional regulator
KM417_18710	COG1674	ftsk spoiiie
KM417_18720	COG0740	serine-type endopeptidase activity
KM417_18725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_18735	COG0527	aspartate kinase activity
KM417_18740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM417_18745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM417_18750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM417_18755	COG1873	PFAM PRC-barrel domain
KM417_18760	COG0612	Peptidase, M16
KM417_18765	COG0726	polysaccharide deacetylase
KM417_18780	COG0196	riboflavin kinase activity
KM417_18785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM417_18795	COG1550	Protein conserved in bacteria
KM417_18805	COG1358	cellular component organization or biogenesis
KM417_18810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM417_18815	COG0195	Participates in both transcription termination and antitermination
KM417_18835	COG0750	zinc metalloprotease
KM417_18845	COG4589	Belongs to the CDS family
KM417_18850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM417_18860	COG0528	UMP kinase activity
KM417_18890	COG4974	Belongs to the 'phage' integrase family
KM417_18900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM417_18910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM417_18950	COG1837	Belongs to the UPF0109 family
KM417_18960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM417_18970	COG0552	protein localization to endoplasmic reticulum
KM417_18975	COG1196	nuclear chromosome segregation
KM417_18985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM417_18990	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_18995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM417_19010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM417_19015	COG1461	Dihydroxyacetone kinase
KM417_19020	COG1302	Protein conserved in bacteria
KM417_19035	COG1564	THIamine pyrophosphokinase
KM417_19040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM417_19045	COG1162	GTPase activity
KM417_19050	COG0515	serine threonine protein kinase
KM417_19050	COG2815	serine threonine protein kinase
KM417_19055	COG0631	protein serine/threonine phosphatase activity
KM417_19065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM417_19065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM417_19075	COG0242	peptide deformylase activity
KM417_19080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM417_19085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM417_19105	COG1561	YicC-like family, N-terminal region
KM417_19110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM417_19120	COG0006	proline dipeptidase activity
KM417_19135	COG3069	C4-dicarboxylate transmembrane transporter activity
KM417_19200	COG0564	pseudouridine synthase activity
KM417_19220	COG3599	regulation of cell shape
KM417_19225	COG2302	S4 RNA-binding domain
KM417_19230	COG0762	integral membrane protein
KM417_19240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM417_19245	COG1496	oxidoreductase activity
KM417_19250	COG1873	PFAM PRC-barrel domain
KM417_19255	COG1191	sigma factor activity
KM417_19260	COG1191	sigma factor activity
KM417_19270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM417_19275	COG0849	cell division
KM417_19280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM417_19285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM417_19295	COG0772	Belongs to the SEDS family
KM417_19310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM417_19315	COG0768	penicillin binding
KM417_19320	COG0768	penicillin binding
KM417_19325	COG4839	cell division protein FtsL
KM417_19340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM417_19355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM417_19360	COG1399	metal-binding, possibly nucleic acid-binding protein
KM417_19410	COG4824	toxin secretion phage lysis holin
KM417_19495	COG4626	Terminase
KM417_19495	COG1802	Transcriptional regulator
KM417_19520	COG0582	viral genome integration into host DNA
KM417_19585	COG0756	dUTP diphosphatase activity
KM417_19600	COG1191	sigma factor activity
KM417_19625	COG1484	DNA-dependent DNA replication
KM417_19655	COG1396	sequence-specific DNA binding
KM417_19670	COG1396	sequence-specific DNA binding
KM417_19685	COG0582	viral genome integration into host DNA
KM417_19695	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM417_19700	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM417_19705	COG3314	Sporulation integral membrane protein YlbJ
KM417_19715	COG0742	ribosomal rna small subunit methyltransferase
KM417_19730	COG3679	Belongs to the UPF0342 family
KM417_19735	COG0406	alpha-ribazole phosphatase activity
KM417_19750	COG2340	Cysteine-rich secretory protein family
KM417_19765	COG3336	cytochrome c oxidase
KM417_19800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM417_19805	COG0772	Belongs to the SEDS family
KM417_19815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM417_19820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM417_19830	COG4896	Protein conserved in bacteria
KM417_19845	COG1217	gtp-binding protein TYPA
KM417_19855	COG0483	inositol monophosphate 1-phosphatase activity
KM417_19875	COG1982	Orn Lys Arg decarboxylase major
KM417_19920	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_19925	COG0022	dehydrogenase e1 component
KM417_19930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_19940	COG0242	peptide deformylase activity
KM417_19945	COG0561	phosphatase activity
KM417_19955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM417_19960	COG0569	domain protein
KM417_19980	COG0583	DNA-binding transcription factor activity
KM417_19985	COG0517	IMP dehydrogenase activity
KM417_19995	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM417_20005	COG4703	Protein of unknown function (DUF1797)
KM417_20020	COG2200	EAL domain
KM417_20025	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_20030	COG1408	metallophosphoesterase
KM417_20040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM417_20075	COG2814	Major facilitator Superfamily
KM417_20095	COG3209	COG3209 Rhs family protein
KM417_20105	COG2205	protein histidine kinase activity
KM417_20115	COG0436	Aminotransferase
KM417_20120	COG1609	Transcriptional regulator
KM417_20125	COG3833	ABC-type maltose transport systems, permease component
KM417_20130	COG1175	transmembrane transport
KM417_20135	COG2182	Extracellular solute-binding protein
KM417_20145	COG0366	Alpha amylase catalytic
KM417_20150	COG3842	ATPase activity
KM417_20190	COG0183	Belongs to the thiolase family
KM417_20225	COG1695	Transcriptional regulator
KM417_20230	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_20240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM417_20250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM417_20255	COG0436	Aminotransferase
KM417_20275	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM417_20295	COG2199	diguanylate cyclase activity
KM417_20300	COG0778	Nitroreductase
KM417_20325	COG2190	(PTS) system
KM417_20325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM417_20325	COG1263	PTS System
KM417_20330	COG3711	transcriptional antiterminator
KM417_20340	COG2188	Transcriptional regulator
KM417_20350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM417_20375	COG1547	Domain of unknown function (DUF309)
KM417_20380	COG0456	acetyltransferase
KM417_20385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM417_20390	COG4086	secreted protein
KM417_20395	COG0561	phosphatase activity
KM417_20400	COG0697	spore germination
KM417_20415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_20440	COG0733	neurotransmitter:sodium symporter activity
KM417_20460	COG1686	Belongs to the peptidase S11 family
KM417_20465	COG1725	Transcriptional regulator
KM417_20470	COG1131	(ABC) transporter
KM417_20485	COG1846	Transcriptional regulator
KM417_20500	COG0598	Magnesium transport protein CorA
KM417_20525	COG4974	Belongs to the 'phage' integrase family
KM417_20535	COG0735	belongs to the Fur family
KM417_20540	COG1300	Membrane
KM417_20560	COG0667	Aldo Keto reductase
KM417_20565	COG0656	L-ascorbic acid biosynthetic process
KM417_20570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM417_20570	COG0456	acetyltransferase
KM417_20580	COG0737	Belongs to the 5'-nucleotidase family
KM417_20580	COG4085	toxin activity
KM417_20580	COG1525	nuclease
KM417_20590	COG0596	Alpha beta hydrolase
KM417_20595	COG2056	Na+-H+ antiporter family
KM417_20600	COG1609	Transcriptional regulator
KM417_20605	COG0456	acetyltransferase
KM417_20610	COG1073	alpha beta
KM417_20625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM417_20625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM417_20630	COG0307	riboflavin synthase, alpha
KM417_20655	COG4106	trans-aconitate 2-methyltransferase activity
KM417_20660	COG1073	alpha beta
KM417_20660	COG2226	methyltransferase
KM417_20675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM417_20685	COG1757	Na H antiporter
KM417_20690	COG0737	Belongs to the 5'-nucleotidase family
KM417_20700	COG1522	sequence-specific DNA binding
KM417_20720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM417_20730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM417_20745	COG0300	oxidoreductase activity
KM417_20755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_20760	COG1760	l-serine dehydratase
KM417_20765	COG1760	l-serine dehydratase
KM417_20785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_20795	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM417_20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_20815	COG1376	ErfK ybiS ycfS ynhG family protein
KM417_20820	COG4129	membrane
KM417_20825	COG1126	abc transporter atp-binding protein
KM417_20830	COG0765	amino acid transport
KM417_20835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM417_20855	COG0772	Belongs to the SEDS family
KM417_20860	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM417_20865	COG0022	dehydrogenase e1 component
KM417_20870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM417_20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM417_20890	COG0280	phosphate acetyltransferase
KM417_20895	COG3829	transcription factor binding
KM417_20895	COG3290	protein histidine kinase activity
KM417_20905	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_20910	COG3093	addiction module antidote protein HigA
KM417_20920	COG0745	RESPONSE REGULATOR receiver
KM417_20925	COG0750	zinc metalloprotease
KM417_20930	COG0497	DNA recombination
KM417_20940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM417_20950	COG0142	geranyltranstransferase activity
KM417_20975	COG1302	Protein conserved in bacteria
KM417_20980	COG0439	Biotin carboxylase
KM417_20985	COG0511	ligase activity, forming carbon-carbon bonds
KM417_21030	COG3854	ATPases associated with a variety of cellular activities
KM417_21055	COG0006	proline dipeptidase activity
KM417_21070	COG3872	metal-dependent enzyme
KM417_21080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM417_21100	COG0095	Lipoate-protein ligase
KM417_21105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_21110	COG1609	Transcriptional regulator
KM417_21120	COG2076	Multidrug Resistance protein
KM417_21125	COG2076	Multidrug Resistance protein
KM417_21160	COG1131	(ABC) transporter
KM417_21165	COG1725	Transcriptional regulator
KM417_21195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_21250	COG4970	Tfp pilus assembly protein FimT
KM417_21260	COG1459	type II secretion system
KM417_21265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM417_21315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM417_21320	COG0646	methionine synthase
KM417_21320	COG1410	methionine synthase
KM417_21325	COG0646	methionine synthase
KM417_21325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM417_21330	COG0626	cystathionine gamma-synthase activity
KM417_21335	COG0626	cystathionine gamma-synthase activity
KM417_21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_21365	COG1940	carbohydrate kinase activity
KM417_21370	COG4483	Protein conserved in bacteria
KM417_21375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM417_21380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM417_21385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM417_21390	COG0704	Plays a role in the regulation of phosphate uptake
KM417_21400	COG0581	inorganic phosphate transmembrane transporter activity
KM417_21405	COG0573	inorganic phosphate transmembrane transporter activity
KM417_21410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM417_21415	COG0768	penicillin binding
KM417_21420	COG0477	Major facilitator Superfamily
KM417_21425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_21450	COG0735	belongs to the Fur family
KM417_21455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM417_21460	COG1121	(ABC) transporter
KM417_21465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_21495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM417_21500	COG2384	SAM-dependent methyltransferase
KM417_21505	COG2010	Cytochrome c
KM417_21510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM417_21515	COG0358	DNA primase activity
KM417_21525	COG0517	IMP dehydrogenase activity
KM417_21540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM417_21545	COG0295	cytidine deaminase activity
KM417_21550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM417_21560	COG1480	7TM receptor with intracellular HD hydrolase
KM417_21565	COG1702	phosphate starvation-inducible protein PhoH
KM417_21580	COG1610	YqeY-like protein
KM417_21585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM417_21590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM417_21595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM417_21625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM417_21630	COG1733	regulation of RNA biosynthetic process
KM417_21655	COG1466	dna polymerase III delta subunit
KM417_21665	COG2333	competence protein COMEC
KM417_21665	COG0658	competence protein
KM417_21670	COG2131	deaminase
KM417_21675	COG1596	polysaccharide export
KM417_21675	COG1555	photosystem II stabilization
KM417_21680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM417_21685	COG2226	methyltransferase
KM417_21690	COG0799	negative regulation of ribosome biogenesis
KM417_21695	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM417_21705	COG1534	Rna-binding protein
KM417_21715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM417_21720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM417_21745	COG1595	DNA-templated transcription, initiation
KM417_21755	COG0778	Nitroreductase
KM417_21760	COG2357	RelA SpoT domain protein
KM417_21770	COG1785	Belongs to the alkaline phosphatase family
KM417_21780	COG2267	carboxylic ester hydrolase activity
KM417_21815	COG1404	Belongs to the peptidase S8 family
KM417_21820	COG3186	Phenylalanine-4-hydroxylase
KM417_21835	COG2259	Doxx family
KM417_21875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_21885	COG1454	alcohol dehydrogenase
KM417_21885	COG1012	belongs to the aldehyde dehydrogenase family
KM417_21890	COG0626	cystathionine gamma-synthase activity
KM417_21895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM417_21920	COG0768	penicillin binding
KM417_21935	COG0826	peptidase U32
KM417_21940	COG0826	peptidase U32
KM417_21945	COG4122	O-methyltransferase activity
KM417_21950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM417_21970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM417_21980	COG0628	permease
KM417_22000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM417_22010	COG0482	sulfurtransferase activity
KM417_22015	COG1104	cysteine desulfurase activity
KM417_22020	COG1959	2 iron, 2 sulfur cluster binding
KM417_22025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM417_22035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM417_22060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM417_22070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM417_22070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM417_22075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM417_22080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM417_22080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM417_22090	COG2244	polysaccharide biosynthetic process
KM417_22095	COG2323	membrane
KM417_22105	COG1862	Preprotein translocase
KM417_22135	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM417_22145	COG0697	spore germination
KM417_22150	COG0697	spore germination
KM417_22155	COG0640	Transcriptional regulator
KM417_22180	COG0157	Belongs to the NadC ModD family
KM417_22185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM417_22190	COG1104	cysteine desulfurase activity
KM417_22195	COG1827	regulation of RNA biosynthetic process
KM417_22200	COG2258	MOSC domain
KM417_22205	COG0077	Prephenate dehydratase
KM417_22210	COG0577	efflux transmembrane transporter activity
KM417_22215	COG0577	efflux transmembrane transporter activity
KM417_22220	COG1136	(ABC) transporter
KM417_22230	COG0745	RESPONSE REGULATOR receiver
KM417_22235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM417_22240	COG3290	protein histidine kinase activity
KM417_22250	COG2868	ribosomal protein
KM417_22260	COG1530	ribonuclease E activity
KM417_22265	COG1994	Peptidase M50
KM417_22270	COG0739	heme binding
KM417_22275	COG2894	cell division
KM417_22295	COG1077	Cell shape determining protein MreB Mrl
KM417_22315	COG0285	dihydrofolate synthase activity
KM417_22320	COG0525	valine-tRNA ligase activity
KM417_22330	COG1388	LysM domain
KM417_22340	COG0113	porphobilinogen synthase activity
KM417_22345	COG1587	Uroporphyrinogen-III synthase
KM417_22355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM417_22365	COG1846	Transcriptional regulator
KM417_22370	COG1764	response to oxidative stress
KM417_22385	COG1067	ATP-dependent peptidase activity
KM417_22385	COG0470	DNA polymerase III
KM417_22430	COG0622	Phosphoesterase
KM417_22445	COG5401	PFAM Sporulation and spore germination
KM417_22465	COG1309	transcriptional regulator
KM417_22480	COG2197	response regulator
KM417_22485	COG2233	PERMEase
KM417_22495	COG0402	S-adenosylhomocysteine deaminase activity
KM417_22500	COG0402	S-adenosylhomocysteine deaminase activity
KM417_22510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM417_22520	COG0444	Belongs to the ABC transporter superfamily
KM417_22525	COG4608	Belongs to the ABC transporter superfamily
KM417_22530	COG3275	phosphorelay sensor kinase activity
KM417_22535	COG3279	Response regulator of the LytR AlgR family
KM417_22550	COG1983	PspC domain protein
KM417_22555	COG1396	sequence-specific DNA binding
KM417_22560	COG0697	spore germination
KM417_22570	COG1959	2 iron, 2 sulfur cluster binding
KM417_22575	COG1668	transmembrane transport
KM417_22580	COG4152	abc transporter atp-binding protein
KM417_22585	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM417_22595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM417_22600	COG1876	peptidase activity
KM417_22605	COG0824	Thioesterase
KM417_22610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM417_22615	COG1053	succinate dehydrogenase
KM417_22620	COG2009	succinate dehydrogenase
KM417_22625	COG1719	4-vinyl reductase, 4VR
KM417_22635	COG3118	belongs to the thioredoxin family
KM417_22640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM417_22645	COG2086	electron transfer activity
KM417_22650	COG1024	Enoyl-CoA hydratase
KM417_22655	COG1309	transcriptional regulator
KM417_22660	COG0318	PFAM AMP-dependent synthetase and ligase
KM417_22680	COG2318	DinB family
KM417_22710	COG1131	(ABC) transporter
KM417_22715	COG2205	protein histidine kinase activity
KM417_22720	COG0745	RESPONSE REGULATOR receiver
KM417_22730	COG4895	conserved protein (DUF2196)
KM417_22735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM417_22750	COG4509	Sortase family
KM417_22755	COG1120	ATPase activity
KM417_22770	COG5386	Cell surface protein
KM417_22780	COG5386	Cell surface protein
KM417_22785	COG1114	Component of the transport system for branched-chain amino acids
KM417_22790	COG1187	pseudouridine synthase activity
KM417_22800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM417_22800	COG1796	DNA polymerase
KM417_22805	COG1286	toxin biosynthetic process
KM417_22850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM417_22860	COG1418	mRNA catabolic process
KM417_22885	COG2814	Major facilitator Superfamily
KM417_22890	COG1566	PFAM secretion protein HlyD family protein
KM417_22895	COG1309	transcriptional regulator
KM417_22900	COG1363	Peptidase, m42
KM417_22925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM417_22935	COG1484	DNA-dependent DNA replication
KM417_22940	COG3611	Membrane attachment protein
KM417_22950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM417_22955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM417_22960	COG0237	dephospho-CoA kinase activity
KM417_22965	COG1971	Probably functions as a manganese efflux pump
KM417_22975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_22975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM417_22980	COG5002	protein histidine kinase activity
KM417_22985	COG0745	RESPONSE REGULATOR receiver
KM417_23005	COG0538	isocitrate dehydrogenase activity
KM417_23010	COG0372	Belongs to the citrate synthase family
KM417_23020	COG0628	permease
KM417_23025	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM417_23050	COG1725	Transcriptional regulator
KM417_23055	COG0281	malic enzyme
KM417_23060	COG0587	DNA-directed DNA polymerase activity
KM417_23075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM417_23095	COG4109	DRTGG domain
KM417_23110	COG0006	proline dipeptidase activity
KM417_23145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_23150	COG0662	Cupin 2, conserved barrel domain protein
KM417_23160	COG1476	TRANSCRIPTIONal
KM417_23175	COG1028	Short-chain dehydrogenase reductase Sdr
KM417_23180	COG0589	response to stress
KM417_23220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_23240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM417_23245	COG0827	DNA restriction-modification system
KM417_23250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM417_23255	COG3874	Sporulation protein YtfJ
KM417_23270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM417_23280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_23295	COG1104	cysteine desulfurase activity
KM417_23305	COG0583	DNA-binding transcription factor activity
KM417_23310	COG0697	spore germination
KM417_23320	COG1956	GAF domain-containing protein
KM417_23325	COG0626	cystathionine gamma-synthase activity
KM417_23355	COG1595	DNA-templated transcription, initiation
KM417_23365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM417_23370	COG0454	-acetyltransferase
KM417_23375	COG0517	IMP dehydrogenase activity
KM417_23380	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM417_23390	COG0745	RESPONSE REGULATOR receiver
KM417_23400	COG0666	response to abiotic stimulus
KM417_23435	COG1609	Transcriptional regulator
KM417_23440	COG4851	CamS sex pheromone cAM373 precursor
KM417_23445	COG3118	belongs to the thioredoxin family
KM417_23455	COG2309	aminopeptidase activity
KM417_23475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_23490	COG1674	ftsk spoiiie
KM417_23500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM417_23505	COG4848	Belongs to the UPF0354 family
KM417_23510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_23515	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM417_23520	COG1363	Peptidase, m42
KM417_23530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_23545	COG0510	thiamine kinase activity
KM417_23550	COG1523	belongs to the glycosyl hydrolase 13 family
KM417_23565	COG1349	DNA-binding transcription factor activity
KM417_23570	COG1187	pseudouridine synthase activity
KM417_23575	COG2244	polysaccharide biosynthetic process
KM417_23580	COG2081	HI0933 family
KM417_23585	COG2814	Major facilitator Superfamily
KM417_23595	COG3832	glyoxalase III activity
KM417_23615	COG1329	Transcriptional regulator
KM417_23625	COG4975	Glucose uptake
KM417_23640	COG0314	molybdopterin synthase activity
KM417_23645	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM417_23650	COG0303	'Molybdopterin
KM417_23660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM417_23685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM417_23695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM417_23735	COG2814	Major facilitator Superfamily
KM417_23740	COG0475	glutathione-regulated potassium exporter activity
KM417_23745	COG0490	domain, Protein
KM417_23750	COG0582	viral genome integration into host DNA
KM417_23760	COG1136	(ABC) transporter
KM417_23780	COG1242	4 iron, 4 sulfur cluster binding
KM417_23785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM417_23790	COG1131	(ABC) transporter
KM417_23800	COG1794	racemase activity, acting on amino acids and derivatives
KM417_23820	COG2267	carboxylic ester hydrolase activity
KM417_23830	COG0671	phosphoesterase, PA-phosphatase related
KM417_23835	COG0438	transferase activity, transferring glycosyl groups
KM417_23845	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM417_23900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM417_23905	COG5002	protein histidine kinase activity
KM417_23910	COG4191	Histidine kinase
KM417_23915	COG2267	carboxylic ester hydrolase activity
KM417_23935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM417_23940	COG1116	anion transmembrane transporter activity
KM417_23945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM417_23970	COG0494	nUDIX hydrolase
KM417_24000	COG0288	reversible hydration of carbon dioxide
KM417_24005	COG1271	oxidase subunit
KM417_24010	COG1294	oxidase, subunit
KM417_24030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_24055	COG1842	Phage shock protein A
KM417_24085	COG5002	protein histidine kinase activity
KM417_24090	COG0745	RESPONSE REGULATOR receiver
KM417_24120	COG1597	lipid kinase activity
KM417_24155	COG0586	Pfam SNARE associated Golgi protein
KM417_24165	COG0577	efflux transmembrane transporter activity
KM417_24170	COG1136	(ABC) transporter
KM417_24175	COG3708	Transcriptional regulator
KM417_24175	COG2207	Transcriptional regulator
KM417_24180	COG0745	RESPONSE REGULATOR receiver
KM417_24185	COG2205	protein histidine kinase activity
KM417_24190	COG0577	efflux transmembrane transporter activity
KM417_24200	COG0577	efflux transmembrane transporter activity
KM417_24205	COG1136	(ABC) transporter
KM417_24225	COG2188	Transcriptional regulator
KM417_24245	COG3964	amidohydrolase
KM417_24275	COG4948	Mandelate Racemase Muconate Lactonizing
KM417_24285	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM417_24290	COG0596	Alpha beta hydrolase
KM417_24295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM417_24300	COG1169	isochorismate synthase
KM417_24305	COG1575	Belongs to the MenA family. Type 1 subfamily
KM417_24310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM417_24330	COG0058	SHG alpha-glucan phosphorylase activity
KM417_24335	COG0297	glycogen (starch) synthase activity
KM417_24340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM417_24460	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM417_24495	COG1285	pathogenesis
KM417_24500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM417_24510	COG0166	Belongs to the GPI family
KM417_24515	COG2155	Conserved Protein
KM417_24520	COG1098	S1 RNA binding domain
KM417_24525	COG0436	Aminotransferase
KM417_24530	COG1522	sequence-specific DNA binding
KM417_24535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM417_24540	COG2267	carboxylic ester hydrolase activity
KM417_24550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM417_24570	COG5018	Exonuclease
KM417_24575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_24595	COG2050	protein possibly involved in aromatic compounds catabolism
KM417_24605	COG1268	BioY protein
KM417_24615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM417_24620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM417_24635	COG3584	3D domain protein
KM417_24650	COG1252	NADH dehydrogenase
KM417_24665	COG3708	Transcriptional regulator
KM417_24680	COG1683	Conserved Protein
KM417_24700	COG0316	Belongs to the HesB IscA family
KM417_24715	COG1252	NADH dehydrogenase
KM417_24730	COG0390	transport system, permease component
KM417_24735	COG2824	Alkylphosphonate utilization operon protein PhnA
KM417_24775	COG4837	Protein of unknown function (DUF1462)
KM417_24780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM417_24790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM417_24795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM417_24805	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM417_24810	COG0647	UMP catabolic process
KM417_24820	COG2445	Protein of unknown function DUF86
KM417_24825	COG1494	fructose-1,6-bisphosphatase
KM417_24840	COG4470	Protein conserved in bacteria
KM417_24850	COG0789	Transcriptional regulator
KM417_24855	COG4377	Putative membrane peptidase family (DUF2324)
KM417_24880	COG0739	heme binding
KM417_24890	COG3377	Domain of unknown function (DUF1805)
KM417_24895	COG0737	Belongs to the 5'-nucleotidase family
KM417_24900	COG1695	Transcriptional regulator
KM417_24910	COG0719	Fe-S assembly protein
KM417_24915	COG0822	iron-sulfur transferase activity
KM417_24920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM417_24925	COG0719	Fe-S assembly protein
KM417_24930	COG0396	ATPase activity
KM417_24935	COG1464	Belongs to the NlpA lipoprotein family
KM417_24940	COG1464	Belongs to the NlpA lipoprotein family
KM417_24945	COG2011	ABC-type metal ion transport system permease component
KM417_24950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM417_24960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM417_24965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM417_24975	COG1393	Belongs to the ArsC family
KM417_25020	COG0039	L-malate dehydrogenase activity
KM417_25040	COG1309	transcriptional regulator
KM417_25045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM417_25050	COG1960	acyl-CoA dehydrogenase activity
KM417_25055	COG0183	Belongs to the thiolase family
KM417_25060	COG1024	Enoyl-CoA hydratase
KM417_25060	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM417_25070	COG1686	Belongs to the peptidase S11 family
KM417_25085	COG0011	TIGRFAM Protein of
KM417_25090	COG0840	transmembrane signaling receptor activity
KM417_25110	COG2814	Major facilitator Superfamily
KM417_25115	COG0531	amino acid
KM417_25125	COG0706	membrane insertase activity
KM417_25135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM417_25170	COG0586	Pfam SNARE associated Golgi protein
KM417_25180	COG1376	ErfK ybiS ycfS ynhG family protein
KM417_25185	COG0745	RESPONSE REGULATOR receiver
KM417_25190	COG5002	protein histidine kinase activity
KM417_25215	COG2151	metal-sulfur cluster biosynthetic enzyme
KM417_25220	COG3227	Zinc metalloprotease (Elastase)
KM417_25225	COG1741	Belongs to the pirin family
KM417_25240	COG0475	glutathione-regulated potassium exporter activity
KM417_25245	COG0490	domain, Protein
KM417_25250	COG1115	amino acid carrier protein
KM417_25255	COG0783	Belongs to the Dps family
KM417_25270	COG1611	Belongs to the LOG family
KM417_25290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_25295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_25300	COG1115	amino acid carrier protein
KM417_25305	COG1115	amino acid carrier protein
KM417_25310	COG2910	NAD(P)H-binding
KM417_25325	COG0656	L-ascorbic acid biosynthetic process
KM417_25330	COG2814	Major facilitator Superfamily
KM417_25335	COG1733	regulation of RNA biosynthetic process
KM417_25345	COG1252	NADH dehydrogenase
KM417_25350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM417_25355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM417_25365	COG3290	protein histidine kinase activity
KM417_25365	COG0840	transmembrane signaling receptor activity
KM417_25375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM417_25380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM417_25395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM417_25450	COG0557	exoribonuclease II activity
KM417_25455	COG1647	Serine aminopeptidase, S33
KM417_25460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM417_25465	COG1346	cytolysis
KM417_25565	COG4695	Portal protein
KM417_25590	COG4974	Belongs to the 'phage' integrase family
KM417_25600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM417_25605	COG0149	triose-phosphate isomerase activity
KM417_25615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM417_25630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM417_25655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM417_25670	COG2323	membrane
KM417_25675	COG0740	serine-type endopeptidase activity
KM417_25680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM417_25690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM417_25700	COG1051	belongs to the nudix hydrolase family
KM417_25710	COG0492	ferredoxin-NADP+ reductase activity
KM417_25715	COG0457	Tetratricopeptide repeat
KM417_25720	COG0110	maltose O-acetyltransferase activity
KM417_25740	COG1950	PFAM Membrane protein of
KM417_25750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM417_25755	COG0556	nucleotide-excision repair
KM417_25775	COG0789	Transcriptional regulator
KM417_25800	COG2855	membrane
KM417_25805	COG0583	DNA-binding transcription factor activity
KM417_25815	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM417_25820	COG0488	(ABC) transporter
KM417_25830	COG1132	(ABC) transporter
KM417_25835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_25840	COG3409	Peptidoglycan-binding domain 1 protein
KM417_25840	COG0793	Belongs to the peptidase S41A family
KM417_25845	COG2177	Part of the ABC transporter FtsEX involved in
KM417_25850	COG2884	Cell division ATP-binding protein ftsE
KM417_25865	COG0653	protein targeting
KM417_25870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM417_25875	COG1278	Cold shock
KM417_25880	COG1040	competence protein
KM417_25885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM417_25890	COG1388	LysM domain
KM417_25890	COG0791	NLP P60 protein
KM417_25895	COG1733	regulation of RNA biosynthetic process
KM417_25900	COG1307	EDD domain protein, DegV family
KM417_25905	COG1739	Uncharacterized protein family UPF0029
KM417_25910	COG1316	TRANSCRIPTIONal
KM417_25915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM417_25920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM417_25925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM417_25935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM417_25935	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM417_25950	COG3394	polysaccharide catabolic process
KM417_25955	COG1486	melibiose metabolic process
KM417_25960	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_25965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_25975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM417_25980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM417_25985	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM417_25995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM417_26000	COG1301	dicarboxylic acid transport
KM417_26010	COG0346	lactoylglutathione lyase activity
KM417_26015	COG1511	domain protein
KM417_26020	COG0583	DNA-binding transcription factor activity
KM417_26025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM417_26040	COG1271	oxidase subunit
KM417_26045	COG1294	oxidase, subunit
KM417_26050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM417_26070	COG2389	metal-binding protein
KM417_26080	COG1368	sulfuric ester hydrolase activity
KM417_26095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM417_26105	COG1215	transferase activity, transferring glycosyl groups
KM417_26110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_26115	COG3584	3D domain protein
KM417_26115	COG1388	LysM domain
KM417_26140	COG4715	Zinc finger, swim domain protein
KM417_26145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM417_26185	COG0577	efflux transmembrane transporter activity
KM417_26190	COG1136	(ABC) transporter
KM417_26225	COG5002	protein histidine kinase activity
KM417_26230	COG0745	RESPONSE REGULATOR receiver
KM417_26235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM417_26250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM417_26255	COG1134	teichoic acid transport
KM417_26260	COG1682	transport, permease protein
KM417_26265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM417_26310	COG1609	Transcriptional regulator
KM417_26325	COG0739	heme binding
KM417_26345	COG2385	sporulation resulting in formation of a cellular spore
KM417_26360	COG4836	Membrane
KM417_26365	COG1007	ATP synthesis coupled electron transport
KM417_26370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM417_26375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM417_26385	COG0839	Belongs to the complex I subunit 6 family
KM417_26400	COG0649	NAD binding
KM417_26405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM417_26420	COG5001	Diguanylate cyclase
KM417_26420	COG3300	MHYT domain
KM417_26470	COG0356	it plays a direct role in the translocation of protons across the membrane
KM417_26505	COG0698	ribose 5-phosphate isomerase
KM417_26515	COG2190	(PTS) system
KM417_26520	COG2259	Doxx family
KM417_26525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM417_26540	COG0009	L-threonylcarbamoyladenylate synthase
KM417_26555	COG2890	protein-(glutamine-N5) methyltransferase activity
KM417_26575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM417_26580	COG1494	fructose-1,6-bisphosphatase
KM417_26600	COG4821	SIS domain
KM417_26610	COG3343	RNA polymerase activity
KM417_26620	COG1960	acyl-CoA dehydrogenase activity
KM417_26625	COG1960	acyl-CoA dehydrogenase activity
KM417_26630	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM417_26635	COG0183	Belongs to the thiolase family
KM417_26640	COG2181	nitrate reductase activity
KM417_26640	COG0247	lactate metabolic process
KM417_26645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM417_26655	COG5001	Diguanylate cyclase
KM417_26655	COG3300	MHYT domain
KM417_26675	COG2197	response regulator
KM417_26680	COG4585	Histidine kinase
KM417_26685	COG0842	Transport permease protein
KM417_26690	COG1131	(ABC) transporter
KM417_26695	COG0024	Methionine aminopeptidase
KM417_26705	COG2234	aminopeptidase activity
KM417_26725	COG1595	DNA-templated transcription, initiation
KM417_26730	COG0018	arginyl-trna synthetase
KM417_26735	COG4506	Protein conserved in bacteria
KM417_26740	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM417_26755	COG0010	Belongs to the arginase family
KM417_26765	COG2814	Major facilitator Superfamily
KM417_26770	COG0789	Transcriptional regulator
KM417_26775	COG0584	glycerophosphoryl diester phosphodiesterase
KM417_26780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM417_26790	COG1994	Peptidase M50
KM417_26800	COG1078	dGTPase activity
KM417_26805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM417_26810	COG1120	ATPase activity
KM417_26815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM417_26840	COG0095	Lipoate-protein ligase
KM417_26845	COG0280	phosphate acetyltransferase
KM417_26860	COG3773	Cell wall hydrolase
KM417_26870	COG2363	Small membrane protein
KM417_26880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM417_26885	COG2233	PERMEase
KM417_26890	COG0561	phosphatase activity
KM417_26895	COG2814	Major facilitator Superfamily
KM417_26905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM417_26910	COG1131	(ABC) transporter
KM417_26915	COG2755	lipolytic protein G-D-S-L family
KM417_26920	COG1609	Transcriptional regulator
KM417_26930	COG0460	homoserine dehydrogenase
KM417_26940	COG2873	o-acetylhomoserine
KM417_26950	COG1011	Hydrolase
KM417_26955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM417_26965	COG2197	response regulator
KM417_26975	COG0351	phosphomethylpyrimidine kinase
KM417_26980	COG3706	GGDEF domain
KM417_26985	COG2879	small protein
KM417_26990	COG1966	Carbon starvation protein
KM417_26995	COG3279	Response regulator of the LytR AlgR family
KM417_27000	COG0477	Major facilitator Superfamily
KM417_27025	COG0840	transmembrane signaling receptor activity
KM417_27035	COG1607	acyl-coa hydrolase
KM417_27050	COG0488	(ABC) transporter
KM417_27070	COG0463	Glycosyl transferase, family 2
KM417_27075	COG1309	transcriptional regulator
KM417_27080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM417_27085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_27085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM417_27090	COG0628	permease
KM417_27105	COG3279	Response regulator of the LytR AlgR family
KM417_27110	COG3275	phosphorelay sensor kinase activity
KM417_27115	COG2814	Major facilitator Superfamily
KM417_27120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM417_27125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM417_27130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM417_27150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM417_27155	COG1272	protein, Hemolysin III
KM417_27175	COG0516	GMP reductase activity
KM417_27180	COG1164	Oligoendopeptidase f
KM417_27200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM417_27205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM417_27210	COG4853	Protein conserved in bacteria
KM417_27215	COG4863	YycH protein
KM417_27220	COG5002	protein histidine kinase activity
KM417_27225	COG0745	RESPONSE REGULATOR receiver
KM417_27255	COG0305	Participates in initiation and elongation during chromosome replication
KM417_27265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM417_27270	COG4241	membrane
KM417_27280	COG0629	single-stranded DNA binding
KM417_27290	COG0012	GTP binding
KM417_27295	COG4481	Protein conserved in bacteria
KM417_27300	COG0668	transmembrane transport
KM417_27310	COG1475	DNA binding
KM417_27315	COG1192	Involved in chromosome partitioning
KM417_27340	COG1847	R3H domain protein
KM417_27345	COG0706	membrane insertase activity
KM417_27355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM417_27405	COG3344	reverse transcriptase
KM417_27485	COG3344	reverse transcriptase
KM417_27675	COG4962	Type ii secretion system protein e
KM417_27810	COG2311	Membrane
KM417_27830	COG4196	transglutaminase domain protein
KM417_27835	COG0671	phosphoesterase, PA-phosphatase related
KM417_27850	COG1215	transferase activity, transferring glycosyl groups
KM417_27855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM417_27860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM417_28020	COG2002	toxin-antitoxin pair type II binding
KM417_28030	COG4974	Belongs to the 'phage' integrase family
KM417_28085	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM417_28095	COG4974	Belongs to the 'phage' integrase family
KM417_28120	COG0457	Tetratricopeptide repeat
KM417_28325	COG0791	NLP P60 protein
KM417_28325	COG0741	lytic transglycosylase activity
KM417_28390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM417_28450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM417_28460	COG4166	transmembrane transport
KM417_28500	COG1280	lysine exporter protein (LysE YggA)
KM417_28525	COG0681	Belongs to the peptidase S26 family
KM417_28600	COG1309	transcriptional regulator
KM417_28605	COG1683	Conserved Protein
KM417_28645	COG1192	Involved in chromosome partitioning