locus-tag	class	description
KM416_00010	COG0592	DNA-directed DNA polymerase activity
KM416_00015	COG2501	S4 domain
KM416_00025	COG0187	DNA topoisomerase II activity
KM416_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM416_00065	COG0516	GMP reductase activity
KM416_00065	COG0517	IMP dehydrogenase activity
KM416_00070	COG1686	Belongs to the peptidase S11 family
KM416_00100	COG1428	Deoxynucleoside kinase
KM416_00105	COG1428	Deoxynucleoside kinase
KM416_00110	COG1335	isochorismatase
KM416_00115	COG0590	tRNA wobble adenosine to inosine editing
KM416_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM416_00180	COG1982	Orn Lys Arg decarboxylase major
KM416_00190	COG0470	DNA polymerase III
KM416_00195	COG1774	PSP1 C-terminal conserved region
KM416_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM416_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM416_00220	COG2002	toxin-antitoxin pair type II binding
KM416_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM416_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM416_00230	COG0084	hydrolase, TatD family'
KM416_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM416_00250	COG4466	Protein conserved in bacteria
KM416_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM416_00270	COG0251	oxidation-reduction process
KM416_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM416_00305	COG2002	toxin-antitoxin pair type II binding
KM416_00310	COG2244	polysaccharide biosynthetic process
KM416_00315	COG3956	TIGRFAM MazG family protein
KM416_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM416_00340	COG1098	S1 RNA binding domain
KM416_00355	COG2208	phosphoserine phosphatase activity
KM416_00360	COG0037	tRNA processing
KM416_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM416_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM416_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM416_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM416_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM416_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM416_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM416_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM416_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM416_00420	COG1396	sequence-specific DNA binding
KM416_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM416_00455	COG3880	PFAM UvrB UvrC protein
KM416_00465	COG0542	response to heat
KM416_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM416_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM416_00500	COG1045	serine acetyltransferase
KM416_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM416_00520	COG3688	RNA-binding protein containing a PIN domain
KM416_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM416_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM416_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM416_00565	COG2813	Specifically methylates the guanine in position
KM416_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM416_00580	COG1358	cellular component organization or biogenesis
KM416_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM416_00710	COG0201	protein transport
KM416_00720	COG0024	Methionine aminopeptidase
KM416_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM416_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM416_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM416_00795	COG0489	protein tyrosine kinase activity
KM416_00805	COG2194	sulfuric ester hydrolase activity
KM416_00810	COG0726	polysaccharide deacetylase
KM416_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM416_00895	COG4856	YbbR-like protein
KM416_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM416_00915	COG0596	Alpha beta hydrolase
KM416_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM416_00940	COG4946	Tricorn protease homolog
KM416_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM416_00940	COG1506	peptidase
KM416_00975	COG2011	ABC-type metal ion transport system permease component
KM416_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM416_00985	COG1464	Belongs to the NlpA lipoprotein family
KM416_00990	COG0604	alcohol dehydrogenase
KM416_01000	COG0277	FAD linked oxidase domain protein
KM416_01005	COG2271	Major facilitator Superfamily
KM416_01015	COG2814	Major facilitator Superfamily
KM416_01030	COG0601	transmembrane transport
KM416_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM416_01040	COG0444	Belongs to the ABC transporter superfamily
KM416_01045	COG4608	Belongs to the ABC transporter superfamily
KM416_01050	COG4166	transmembrane transport
KM416_01060	COG2207	Transcriptional regulator
KM416_01075	COG4166	transmembrane transport
KM416_01080	COG4166	transmembrane transport
KM416_01085	COG0656	L-ascorbic acid biosynthetic process
KM416_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM416_01105	COG4149	molybdate abc transporter
KM416_01115	COG1910	domain protein
KM416_01125	COG0583	DNA-binding transcription factor activity
KM416_01130	COG0697	spore germination
KM416_01145	COG0204	Acyl-transferase
KM416_01155	COG1609	Transcriptional regulator
KM416_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_01175	COG0084	hydrolase, TatD family'
KM416_01180	COG5298	Protein conserved in bacteria
KM416_01205	COG0488	(ABC) transporter
KM416_01220	COG0747	negative chemotaxis
KM416_01225	COG0601	transmembrane transport
KM416_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM416_01235	COG0444	Belongs to the ABC transporter superfamily
KM416_01240	COG4608	Belongs to the ABC transporter superfamily
KM416_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM416_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM416_01290	COG2814	Major facilitator Superfamily
KM416_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM416_01310	COG4294	response to UV
KM416_01315	COG0457	Tetratricopeptide repeat
KM416_01315	COG0705	Rhomboid family
KM416_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM416_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM416_01335	COG0864	Transcriptional regulator
KM416_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM416_01345	COG2183	response to ionizing radiation
KM416_01440	COG0802	atpase or kinase
KM416_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM416_01450	COG0456	acetyltransferase
KM416_01460	COG0488	(ABC) transporter
KM416_01475	COG1266	CAAX protease self-immunity
KM416_01495	COG2252	PERMEase
KM416_01505	COG5002	protein histidine kinase activity
KM416_01535	COG2226	methyltransferase
KM416_01575	COG1968	undecaprenyl-diphosphatase activity
KM416_01590	COG2205	protein histidine kinase activity
KM416_01595	COG0745	RESPONSE REGULATOR receiver
KM416_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM416_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM416_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM416_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM416_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM416_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM416_01670	COG0151	Belongs to the GarS family
KM416_01695	COG0210	DNA helicase
KM416_01705	COG4851	CamS sex pheromone cAM373 precursor
KM416_01725	COG1335	isochorismatase
KM416_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM416_01735	COG2011	ABC-type metal ion transport system permease component
KM416_01740	COG1464	Belongs to the NlpA lipoprotein family
KM416_01760	COG1846	Transcriptional regulator
KM416_01785	COG1597	lipid kinase activity
KM416_01790	COG0546	phosphoglycolate phosphatase activity
KM416_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM416_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM416_01810	COG2076	Multidrug Resistance protein
KM416_01815	COG2309	aminopeptidase activity
KM416_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM416_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM416_01850	COG4807	Protein conserved in bacteria
KM416_01875	COG1757	Na H antiporter
KM416_01880	COG1473	amidohydrolase
KM416_01895	COG0450	alkyl hydroperoxide reductase
KM416_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_01940	COG0166	Belongs to the GPI family
KM416_01975	COG5002	protein histidine kinase activity
KM416_01995	COG3541	Predicted nucleotidyltransferase
KM416_02000	COG2814	Major facilitator Superfamily
KM416_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM416_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM416_02015	COG0765	amino acid transport
KM416_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM416_02030	COG0840	transmembrane signaling receptor activity
KM416_02035	COG0840	transmembrane signaling receptor activity
KM416_02040	COG0366	Alpha amylase catalytic
KM416_02045	COG2190	(PTS) system
KM416_02045	COG1263	PTS System
KM416_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM416_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM416_02100	COG1116	anion transmembrane transporter activity
KM416_02105	COG0488	(ABC) transporter
KM416_02150	COG2270	Major facilitator Superfamily
KM416_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM416_02180	COG2310	stress, protein
KM416_02185	COG2310	stress, protein
KM416_02190	COG2310	stress, protein
KM416_02195	COG0861	Integral membrane protein TerC family
KM416_02205	COG3853	Toxic anion resistance protein (TelA)
KM416_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM416_02230	COG1295	ribonuclease BN
KM416_02235	COG2217	Heavy metal translocating P-type atpase
KM416_02240	COG0697	spore germination
KM416_02260	COG0586	Pfam SNARE associated Golgi protein
KM416_02275	COG3871	stress protein (general stress protein 26)
KM416_02280	COG0387	Pfam Sodium calcium exchanger
KM416_02290	COG0535	radical SAM domain protein
KM416_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM416_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM416_02325	COG0582	viral genome integration into host DNA
KM416_02335	COG1396	sequence-specific DNA binding
KM416_02350	COG1396	sequence-specific DNA binding
KM416_02385	COG1484	DNA-dependent DNA replication
KM416_02615	COG0101	tRNA pseudouridine synthase activity
KM416_02625	COG3829	transcription factor binding
KM416_02635	COG0833	amino acid
KM416_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM416_02670	COG1263	PTS System
KM416_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM416_02690	COG0463	Glycosyl transferase, family 2
KM416_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM416_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM416_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM416_02745	COG1228	amidohydrolase
KM416_02750	COG1090	epimerase
KM416_02780	COG1988	membrane-bound metal-dependent
KM416_02785	COG1194	a g-specific adenine glycosylase
KM416_02810	COG1132	(ABC) transporter
KM416_02815	COG4129	membrane
KM416_02820	COG0070	glutamate synthase
KM416_02820	COG0069	glutamate synthase activity
KM416_02820	COG0067	glutamate synthase
KM416_02830	COG4555	ABC transporter
KM416_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM416_02855	COG0735	belongs to the Fur family
KM416_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM416_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM416_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM416_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM416_03005	COG2766	serine protein kinase
KM416_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM416_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM416_03040	COG2268	Band 7 protein
KM416_03050	COG3290	protein histidine kinase activity
KM416_03055	COG4565	transcriptional regulatory protein
KM416_03060	COG2851	Citrate transporter
KM416_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM416_03085	COG3842	ATPase activity
KM416_03090	COG1175	transmembrane transport
KM416_03095	COG0395	ABC-type sugar transport system, permease component
KM416_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM416_03110	COG0745	RESPONSE REGULATOR receiver
KM416_03115	COG5002	protein histidine kinase activity
KM416_03125	COG4990	cell redox homeostasis
KM416_03135	COG3290	protein histidine kinase activity
KM416_03140	COG4565	transcriptional regulatory protein
KM416_03145	COG3493	citrate carrier protein
KM416_03150	COG0281	malic enzyme
KM416_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_03175	COG5002	protein histidine kinase activity
KM416_03180	COG0745	RESPONSE REGULATOR receiver
KM416_03185	COG0454	-acetyltransferase
KM416_03185	COG0456	acetyltransferase
KM416_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM416_03195	COG3383	formate dehydrogenase (NAD+) activity
KM416_03200	COG2427	Protein of unknown function (DUF1641)
KM416_03215	COG0531	amino acid
KM416_03220	COG0640	Transcriptional regulator
KM416_03225	COG2217	Heavy metal translocating P-type atpase
KM416_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM416_03245	COG3227	Zinc metalloprotease (Elastase)
KM416_03265	COG2720	vancomycin resistance protein
KM416_03270	COG1316	TRANSCRIPTIONal
KM416_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_03280	COG0346	lactoylglutathione lyase activity
KM416_03285	COG1253	flavin adenine dinucleotide binding
KM416_03290	COG1027	Aspartate ammonia-lyase
KM416_03295	COG1620	l-lactate permease
KM416_03310	COG3104	oligopeptide transport
KM416_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_03335	COG2226	methyltransferase
KM416_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM416_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM416_03355	COG4548	von Willebrand factor, type A
KM416_03360	COG0714	Associated with various cellular activities
KM416_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM416_03385	COG0531	amino acid
KM416_03390	COG2188	Transcriptional regulator
KM416_03395	COG1263	PTS System
KM416_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_03400	COG0366	Alpha amylase catalytic
KM416_03415	COG0697	spore germination
KM416_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM416_03430	COG1115	amino acid carrier protein
KM416_03435	COG1126	abc transporter atp-binding protein
KM416_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM416_03445	COG0765	amino acid transport
KM416_03450	COG0765	amino acid transport
KM416_03455	COG0833	amino acid
KM416_03480	COG2378	regulation of single-species biofilm formation
KM416_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM416_03490	COG5002	protein histidine kinase activity
KM416_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM416_03520	COG0747	negative chemotaxis
KM416_03530	COG0601	transmembrane transport
KM416_03535	COG4608	Belongs to the ABC transporter superfamily
KM416_03545	COG2271	Major facilitator Superfamily
KM416_03550	COG1846	Transcriptional regulator
KM416_03560	COG1609	Transcriptional regulator
KM416_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM416_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM416_03585	COG1879	ABC-type sugar transport system periplasmic component
KM416_03610	COG1063	alcohol dehydrogenase
KM416_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM416_03650	COG1968	undecaprenyl-diphosphatase activity
KM416_03655	COG0840	transmembrane signaling receptor activity
KM416_03660	COG3584	3D domain protein
KM416_03660	COG1388	LysM domain
KM416_03665	COG1476	TRANSCRIPTIONal
KM416_03680	COG3104	oligopeptide transport
KM416_03685	COG1114	Component of the transport system for branched-chain amino acids
KM416_03700	COG1113	amino acid transport
KM416_03705	COG2252	PERMEase
KM416_03730	COG0569	domain protein
KM416_03730	COG0475	glutathione-regulated potassium exporter activity
KM416_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM416_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM416_03755	COG0833	amino acid
KM416_03760	COG4990	cell redox homeostasis
KM416_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM416_03780	COG0697	spore germination
KM416_03785	COG0531	amino acid
KM416_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM416_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM416_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM416_03805	COG1918	ferrous iron import across plasma membrane
KM416_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM416_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM416_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM416_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM416_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM416_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM416_03975	COG1116	anion transmembrane transporter activity
KM416_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM416_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM416_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM416_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM416_04000	COG2104	thiamine diphosphate biosynthetic process
KM416_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM416_04015	COG0351	phosphomethylpyrimidine kinase
KM416_04055	COG2205	protein histidine kinase activity
KM416_04060	COG2814	Major facilitator Superfamily
KM416_04065	COG1846	Transcriptional regulator
KM416_04080	COG2252	PERMEase
KM416_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM416_04105	COG1621	beta-fructofuranosidase activity
KM416_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_04110	COG1263	PTS System
KM416_04115	COG1609	Transcriptional regulator
KM416_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM416_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM416_04165	COG0778	Nitroreductase
KM416_04170	COG2719	SpoVR family
KM416_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM416_04200	COG1937	Protein conserved in bacteria
KM416_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM416_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM416_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM416_04235	COG0730	response to heat
KM416_04245	COG1316	TRANSCRIPTIONal
KM416_04250	COG0604	alcohol dehydrogenase
KM416_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM416_04270	COG3711	transcriptional antiterminator
KM416_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM416_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM416_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM416_04300	COG1388	LysM domain
KM416_04300	COG3584	3D domain protein
KM416_04305	COG0577	efflux transmembrane transporter activity
KM416_04310	COG1136	(ABC) transporter
KM416_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM416_04335	COG1114	Component of the transport system for branched-chain amino acids
KM416_04340	COG3546	catalase activity
KM416_04375	COG0586	Pfam SNARE associated Golgi protein
KM416_04410	COG0531	amino acid
KM416_04415	COG0475	glutathione-regulated potassium exporter activity
KM416_04425	COG1737	Transcriptional regulator
KM416_04435	COG1263	PTS System
KM416_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_04445	COG2259	Doxx family
KM416_04460	COG0697	spore germination
KM416_04465	COG1522	sequence-specific DNA binding
KM416_04480	COG2076	Multidrug Resistance protein
KM416_04485	COG1309	transcriptional regulator
KM416_04490	COG2814	Major facilitator Superfamily
KM416_04495	COG1733	regulation of RNA biosynthetic process
KM416_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM416_04510	COG4533	DNA binding
KM416_04515	COG2211	Major facilitator Superfamily
KM416_04525	COG0693	protein deglycase activity
KM416_04530	COG0693	protein deglycase activity
KM416_04530	COG0753	catalase activity
KM416_04540	COG0531	amino acid
KM416_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM416_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM416_04560	COG1132	(ABC) transporter
KM416_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM416_04575	COG0765	amino acid transport
KM416_04580	COG1126	abc transporter atp-binding protein
KM416_04595	COG0189	ligase activity
KM416_04625	COG0028	Belongs to the TPP enzyme family
KM416_04630	COG3527	Alpha-acetolactate decarboxylase
KM416_04645	COG0561	phosphatase activity
KM416_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM416_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM416_04695	COG0653	protein targeting
KM416_04700	COG2244	polysaccharide biosynthetic process
KM416_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM416_04715	COG4196	transglutaminase domain protein
KM416_04730	COG1696	Membrane protein involved in D-alanine export
KM416_04745	COG1024	Enoyl-CoA hydratase
KM416_04765	COG1363	Peptidase, m42
KM416_04785	COG3938	Belongs to the proline racemase family
KM416_04825	COG0601	transmembrane transport
KM416_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM416_04840	COG4608	Belongs to the ABC transporter superfamily
KM416_04845	COG0322	excinuclease ABC activity
KM416_04875	COG0477	Major facilitator Superfamily
KM416_04880	COG3290	protein histidine kinase activity
KM416_04885	COG4565	transcriptional regulatory protein
KM416_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM416_04920	COG0789	Transcriptional regulator
KM416_04920	COG4978	Transcriptional regulator
KM416_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM416_04975	COG0477	Major facilitator Superfamily
KM416_05020	COG3320	Male sterility
KM416_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM416_05025	COG1309	transcriptional regulator
KM416_05045	COG1183	phosphatidylcholine synthase activity
KM416_05065	COG2376	Dihydroxyacetone kinase
KM416_05075	COG2376	Dihydroxyacetone kinase
KM416_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM416_05085	COG1959	2 iron, 2 sulfur cluster binding
KM416_05115	COG2770	Histidine kinase
KM416_05115	COG3437	response regulator, receiver
KM416_05165	COG3237	CsbD-like
KM416_05190	COG1191	sigma factor activity
KM416_05200	COG2208	phosphoserine phosphatase activity
KM416_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM416_05210	COG2198	Histidine kinase
KM416_05210	COG2205	protein histidine kinase activity
KM416_05210	COG0784	Response regulator, receiver
KM416_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM416_05265	COG0420	3'-5' exonuclease activity
KM416_05270	COG4717	serine-type aminopeptidase activity
KM416_05290	COG1309	transcriptional regulator
KM416_05295	COG2814	Major facilitator Superfamily
KM416_05300	COG0346	lactoylglutathione lyase activity
KM416_05310	COG0346	lactoylglutathione lyase activity
KM416_05315	COG0457	Tetratricopeptide repeat
KM416_05320	COG2267	carboxylic ester hydrolase activity
KM416_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM416_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM416_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM416_05395	COG0477	Major facilitator Superfamily
KM416_05400	COG0477	Major facilitator Superfamily
KM416_05410	COG3973	AAA domain
KM416_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM416_05435	COG4980	gas vesicle protein
KM416_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM416_05445	COG1131	(ABC) transporter
KM416_05450	COG4473	ABC transporter
KM416_05465	COG1309	transcriptional regulator
KM416_05475	COG3402	PFAM membrane-flanked domain
KM416_05525	COG3402	PFAM membrane-flanked domain
KM416_05530	COG3428	Bacterial PH domain
KM416_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM416_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM416_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM416_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM416_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM416_05590	COG1309	transcriptional regulator
KM416_05595	COG1511	domain protein
KM416_05620	COG1609	Transcriptional regulator
KM416_05630	COG1234	tRNA 3'-trailer cleavage
KM416_05635	COG0095	Lipoate-protein ligase
KM416_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_05675	COG3209	COG3209 Rhs family protein
KM416_05715	COG1078	dGTPase activity
KM416_05725	COG1595	DNA-templated transcription, initiation
KM416_05730	COG2207	Transcriptional regulator
KM416_05730	COG3708	Transcriptional regulator
KM416_05745	COG2205	protein histidine kinase activity
KM416_05750	COG0745	RESPONSE REGULATOR receiver
KM416_05775	COG0501	Belongs to the peptidase M48B family
KM416_05780	COG0840	transmembrane signaling receptor activity
KM416_05785	COG0697	spore germination
KM416_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM416_05810	COG2224	Isocitrate lyase
KM416_05835	COG4903	ComK protein
KM416_05840	COG0398	Pfam SNARE associated Golgi protein
KM416_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM416_05855	COG1074	ATP-dependent DNA helicase activity
KM416_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM416_05925	COG0367	asparagine synthase
KM416_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM416_05935	COG0753	catalase activity
KM416_05940	COG0004	ammonium transporteR
KM416_05960	COG2996	Protein conserved in bacteria
KM416_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM416_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_05995	COG0561	phosphatase activity
KM416_06005	COG0542	response to heat
KM416_06015	COG2267	carboxylic ester hydrolase activity
KM416_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM416_06040	COG5504	Zn-dependent protease
KM416_06050	COG0180	Tryptophanyl-tRNA synthetase
KM416_06060	COG4166	transmembrane transport
KM416_06065	COG0601	transmembrane transport
KM416_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM416_06075	COG0444	Belongs to the ABC transporter superfamily
KM416_06080	COG4608	Belongs to the ABC transporter superfamily
KM416_06085	COG0534	Mate efflux family protein
KM416_06090	COG4166	transmembrane transport
KM416_06105	COG0861	Integral membrane protein TerC family
KM416_06110	COG4862	establishment of competence for transformation
KM416_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM416_06125	COG1164	Oligoendopeptidase f
KM416_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM416_06140	COG2346	COG2346, Truncated hemoglobins
KM416_06145	COG4116	CYTH
KM416_06155	COG2357	RelA SpoT domain protein
KM416_06165	COG0564	pseudouridine synthase activity
KM416_06185	COG1216	Glycosyl transferase, family 2
KM416_06185	COG0463	Glycosyl transferase, family 2
KM416_06205	COG0457	Tetratricopeptide repeat
KM416_06205	COG0463	Glycosyl transferase, family 2
KM416_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM416_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM416_06285	COG2153	protein acetylation
KM416_06295	COG2382	esterase
KM416_06310	COG5492	domain, Protein
KM416_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM416_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM416_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM416_06360	COG1620	l-lactate permease
KM416_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM416_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM416_06430	COG1476	TRANSCRIPTIONal
KM416_06490	COG2226	methyltransferase
KM416_06500	COG1686	Belongs to the peptidase S11 family
KM416_06505	COG0681	Belongs to the peptidase S26 family
KM416_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM416_06545	COG3842	ATPase activity
KM416_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM416_06555	COG1177	transmembrane transport
KM416_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM416_06570	COG2409	Drug exporters of the RND superfamily
KM416_06580	COG0564	pseudouridine synthase activity
KM416_06590	COG2340	Cysteine-rich secretory protein family
KM416_06595	COG0247	lactate metabolic process
KM416_06600	COG0277	FAD linked oxidase domain protein
KM416_06605	COG3835	regulator
KM416_06615	COG0745	RESPONSE REGULATOR receiver
KM416_06620	COG5002	protein histidine kinase activity
KM416_06625	COG2186	Transcriptional regulator
KM416_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM416_06660	COG2116	formate transmembrane transporter activity
KM416_06665	COG0861	Integral membrane protein TerC family
KM416_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM416_06680	COG2030	dehydratase
KM416_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM416_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM416_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM416_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM416_06760	COG1349	DNA-binding transcription factor activity
KM416_06780	COG2861	carbohydrate metabolic process
KM416_06790	COG3852	Histidine kinase
KM416_06795	COG1846	Transcriptional regulator
KM416_06805	COG2318	DinB family
KM416_06810	COG5002	protein histidine kinase activity
KM416_06820	COG0720	synthase
KM416_06835	COG4873	Protein conserved in bacteria
KM416_06865	COG1780	Probably involved in ribonucleotide reductase function
KM416_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM416_06890	COG1725	Transcriptional regulator
KM416_06895	COG1131	(ABC) transporter
KM416_06905	COG1131	(ABC) transporter
KM416_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM416_06925	COG1522	sequence-specific DNA binding
KM416_06935	COG1335	isochorismatase
KM416_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM416_06950	COG2070	2-Nitropropane dioxygenase
KM416_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM416_06965	COG1696	Membrane protein involved in D-alanine export
KM416_06990	COG0716	FMN binding
KM416_07005	COG3173	Aminoglycoside phosphotransferase
KM416_07025	COG0534	Mate efflux family protein
KM416_07030	COG1968	undecaprenyl-diphosphatase activity
KM416_07045	COG1846	Transcriptional regulator
KM416_07055	COG1301	dicarboxylic acid transport
KM416_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM416_07065	COG4709	membrane
KM416_07070	COG3874	Sporulation protein YtfJ
KM416_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM416_07100	COG0028	Belongs to the TPP enzyme family
KM416_07105	COG0440	acetolactate synthase activity
KM416_07110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM416_07120	COG0473	3-isopropylmalate dehydrogenase activity
KM416_07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM416_07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM416_07195	COG1183	phosphatidylcholine synthase activity
KM416_07200	COG1368	sulfuric ester hydrolase activity
KM416_07210	COG0019	diaminopimelate decarboxylase activity
KM416_07230	COG0529	Catalyzes the synthesis of activated sulfate
KM416_07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM416_07255	COG1648	precorrin-2 dehydrogenase activity
KM416_07260	COG0733	neurotransmitter:sodium symporter activity
KM416_07280	COG1757	Na H antiporter
KM416_07295	COG4758	membrane
KM416_07300	COG4585	Histidine kinase
KM416_07305	COG2197	response regulator
KM416_07315	COG1114	Component of the transport system for branched-chain amino acids
KM416_07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM416_07350	COG1017	nitric oxide dioxygenase activity
KM416_07350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM416_07365	COG0730	response to heat
KM416_07370	COG0306	phosphate transporter
KM416_07375	COG1392	Phosphate transport regulator
KM416_07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM416_07395	COG3852	Histidine kinase
KM416_07400	COG1801	Protein of unknown function DUF72
KM416_07410	COG0582	viral genome integration into host DNA
KM416_07415	COG5002	protein histidine kinase activity
KM416_07435	COG0392	lysyltransferase activity
KM416_07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM416_07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM416_07455	COG1686	Belongs to the peptidase S11 family
KM416_07460	COG2715	membrane protein required for spore maturation
KM416_07465	COG0700	Nucleoside recognition
KM416_07470	COG1187	pseudouridine synthase activity
KM416_07480	COG1333	cytochrome c biogenesis protein
KM416_07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM416_07490	COG0745	RESPONSE REGULATOR receiver
KM416_07495	COG5002	protein histidine kinase activity
KM416_07500	COG2096	Adenosyltransferase
KM416_07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM416_07520	COG1141	Ferredoxin
KM416_07525	COG4955	Helix-turn-helix domain
KM416_07530	COG0514	ATP-dependent DNA helicase (RecQ)
KM416_07535	COG1266	CAAX protease self-immunity
KM416_07555	COG4862	establishment of competence for transformation
KM416_07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM416_07580	COG0492	ferredoxin-NADP+ reductase activity
KM416_07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM416_07670	COG0142	geranyltranstransferase activity
KM416_07680	COG0142	geranyltranstransferase activity
KM416_07700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM416_07705	COG0457	Tetratricopeptide repeat
KM416_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM416_07735	COG4347	Protein of unknown function (DUF1405)
KM416_07750	COG2738	Putative neutral zinc metallopeptidase
KM416_07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_07765	COG1694	Mazg nucleotide pyrophosphohydrolase
KM416_07780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM416_07785	COG0438	transferase activity, transferring glycosyl groups
KM416_07820	COG1199	ATP-dependent helicase activity
KM416_07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM416_07840	COG3935	DnaD domain protein
KM416_07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM416_07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM416_07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM416_07915	COG0116	Belongs to the methyltransferase superfamily
KM416_07925	COG1199	ATP-dependent helicase activity
KM416_07930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM416_07940	COG3173	Aminoglycoside phosphotransferase
KM416_07945	COG0024	Methionine aminopeptidase
KM416_07955	COG2233	PERMEase
KM416_07960	COG2311	Membrane
KM416_07965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM416_07975	COG0456	acetyltransferase
KM416_08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM416_08050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM416_08065	COG1215	transferase activity, transferring glycosyl groups
KM416_08070	COG0438	transferase activity, transferring glycosyl groups
KM416_08085	COG0454	-acetyltransferase
KM416_08105	COG0328	RNA-DNA hybrid ribonuclease activity
KM416_08145	COG1280	lysine exporter protein (LysE YggA)
KM416_08160	COG3162	membrane
KM416_08165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM416_08170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM416_08180	COG0475	glutathione-regulated potassium exporter activity
KM416_08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM416_08190	COG0789	Transcriptional regulator
KM416_08190	COG4978	Transcriptional regulator
KM416_08200	COG2323	membrane
KM416_08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM416_08260	COG1923	regulation of RNA biosynthetic process
KM416_08270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM416_08275	COG1360	Flagellar Motor Protein
KM416_08280	COG2201	protein-glutamate methylesterase activity
KM416_08285	COG0643	Histidine kinase
KM416_08285	COG2198	Histidine kinase
KM416_08290	COG2198	Histidine kinase
KM416_08290	COG0643	Histidine kinase
KM416_08295	COG1776	CheC inhibitor of MCP methylation
KM416_08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM416_08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM416_08330	COG1256	bacterial-type flagellum assembly
KM416_08355	COG1815	bacterial-type flagellum-dependent cell motility
KM416_08360	COG1558	bacterial-type flagellum-dependent cell motility
KM416_08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM416_08385	COG1157	protein secretion by the type III secretion system
KM416_08425	COG0835	chemotaxis
KM416_08425	COG0784	Response regulator, receiver
KM416_08435	COG0463	Glycosyl transferase, family 2
KM416_08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM416_08475	COG0741	lytic transglycosylase activity
KM416_08490	COG1776	CheC inhibitor of MCP methylation
KM416_08490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM416_08500	COG1338	Plays a role in the flagellum-specific transport system
KM416_08505	COG1987	bacterial-type flagellum assembly
KM416_08515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM416_08520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM416_08525	COG1419	protein localization to endoplasmic reticulum
KM416_08530	COG4786	Flagellar basal body rod
KM416_08535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM416_08560	COG1309	transcriptional regulator
KM416_08580	COG2329	Antibiotic biosynthesis monooxygenase
KM416_08605	COG0583	DNA-binding transcription factor activity
KM416_08610	COG3842	ATPase activity
KM416_08615	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM416_08625	COG1234	tRNA 3'-trailer cleavage
KM416_08650	COG1686	Belongs to the peptidase S11 family
KM416_08660	COG0406	alpha-ribazole phosphatase activity
KM416_08690	COG0367	asparagine synthase
KM416_08720	COG1802	Transcriptional regulator
KM416_08725	COG0697	spore germination
KM416_08730	COG0523	cobalamin synthesis protein
KM416_08735	COG0701	Predicted permease
KM416_08745	COG1216	Glycosyl transferase, family 2
KM416_08745	COG0438	transferase activity, transferring glycosyl groups
KM416_08750	COG1757	Na H antiporter
KM416_08755	COG0114	fumarate hydratase activity
KM416_08780	COG3340	Belongs to the peptidase S51 family
KM416_08800	COG0785	Cytochrome C biogenesis protein
KM416_08830	COG2733	membrane
KM416_08865	COG1131	(ABC) transporter
KM416_08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM416_08885	COG0528	UMP kinase activity
KM416_08895	COG1027	Aspartate ammonia-lyase
KM416_08900	COG0281	malic enzyme
KM416_08905	COG4191	Histidine kinase
KM416_08910	COG0784	Response regulator, receiver
KM416_08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM416_08970	COG1051	belongs to the nudix hydrolase family
KM416_08975	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM416_08985	COG2814	Major facilitator Superfamily
KM416_09000	COG1966	Carbon starvation protein
KM416_09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM416_09035	COG2223	nitrite transmembrane transporter activity
KM416_09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM416_09055	COG2244	polysaccharide biosynthetic process
KM416_09060	COG0733	neurotransmitter:sodium symporter activity
KM416_09070	COG5566	PFAM Mor transcription activator
KM416_09075	COG2323	membrane
KM416_09090	COG2084	Dehydrogenase
KM416_09105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM416_09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM416_09120	COG0028	Belongs to the TPP enzyme family
KM416_09125	COG0440	acetolactate synthase activity
KM416_09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM416_09140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM416_09165	COG2814	Major facilitator Superfamily
KM416_09170	COG3384	dioxygenase
KM416_09180	COG3279	Response regulator of the LytR AlgR family
KM416_09185	COG0427	acetyl-CoA hydrolase
KM416_09205	COG1073	alpha beta
KM416_09235	COG0535	radical SAM domain protein
KM416_09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_09260	COG1914	H( )-stimulated, divalent metal cation uptake system
KM416_09275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM416_09305	COG2390	Transcriptional regulator
KM416_09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM416_09335	COG4224	UPF0291 protein
KM416_09355	COG0006	proline dipeptidase activity
KM416_09360	COG2132	Multicopper oxidase
KM416_09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM416_09390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM416_09405	COG1276	copper resistance
KM416_09405	COG2372	response to copper ion
KM416_09410	COG4549	nuclear export factor GLE1
KM416_09420	COG0697	spore germination
KM416_09425	COG0583	DNA-binding transcription factor activity
KM416_09430	COG1959	2 iron, 2 sulfur cluster binding
KM416_09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM416_09440	COG0778	Nitroreductase
KM416_09450	COG0628	permease
KM416_09460	COG1231	oxidoreductase activity
KM416_09465	COG0523	cobalamin synthesis protein
KM416_09480	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_09485	COG2030	dehydratase
KM416_09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_09500	COG0411	ABC transporter
KM416_09520	COG0583	DNA-binding transcription factor activity
KM416_09540	COG1846	Transcriptional regulator
KM416_09550	COG1271	oxidase subunit
KM416_09555	COG1294	oxidase, subunit
KM416_09560	COG4988	ABC transporter
KM416_09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM416_09585	COG1686	Belongs to the peptidase S11 family
KM416_09600	COG1388	LysM domain
KM416_09600	COG0791	NLP P60 protein
KM416_09615	COG0745	RESPONSE REGULATOR receiver
KM416_09620	COG5002	protein histidine kinase activity
KM416_09630	COG0300	oxidoreductase activity
KM416_09665	COG0460	homoserine dehydrogenase
KM416_09690	COG1316	TRANSCRIPTIONal
KM416_09700	COG0745	RESPONSE REGULATOR receiver
KM416_09705	COG5002	protein histidine kinase activity
KM416_09720	COG1285	pathogenesis
KM416_09725	COG1247	-acetyltransferase
KM416_09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM416_09755	COG1082	Xylose isomerase domain protein TIM barrel
KM416_09770	COG1279	arginine transmembrane transporter activity
KM416_09780	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM416_09820	COG2002	toxin-antitoxin pair type II binding
KM416_09825	COG1404	Belongs to the peptidase S8 family
KM416_09830	COG0640	Transcriptional regulator
KM416_09835	COG0667	Aldo Keto reductase
KM416_09840	COG2814	Major facilitator Superfamily
KM416_09865	COG0840	transmembrane signaling receptor activity
KM416_09880	COG3949	Membrane
KM416_09885	COG0783	Belongs to the Dps family
KM416_09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM416_09910	COG1231	oxidoreductase activity
KM416_09920	COG4989	oxidoreductase activity
KM416_09925	COG0523	cobalamin synthesis protein
KM416_09930	COG0456	acetyltransferase
KM416_09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM416_09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM416_09995	COG0702	epimerase
KM416_10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM416_10015	COG4166	transmembrane transport
KM416_10030	COG0406	alpha-ribazole phosphatase activity
KM416_10040	COG5337	Spore coat protein CotH
KM416_10045	COG1051	belongs to the nudix hydrolase family
KM416_10050	COG0586	Pfam SNARE associated Golgi protein
KM416_10055	COG2244	polysaccharide biosynthetic process
KM416_10065	COG0701	Predicted permease
KM416_10070	COG3689	TIGRFAM TIGR03943 family protein
KM416_10075	COG1607	acyl-coa hydrolase
KM416_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM416_10100	COG0702	epimerase
KM416_10105	COG2839	Protein conserved in bacteria
KM416_10110	COG1253	flavin adenine dinucleotide binding
KM416_10125	COG1114	Component of the transport system for branched-chain amino acids
KM416_10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM416_10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM416_10160	COG1876	peptidase activity
KM416_10170	COG0154	amidase activity
KM416_10175	COG2211	Major facilitator Superfamily
KM416_10195	COG0561	phosphatase activity
KM416_10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM416_10210	COG4106	trans-aconitate 2-methyltransferase activity
KM416_10225	COG1819	glycosyl
KM416_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_10260	COG0456	acetyltransferase
KM416_10310	COG3874	Sporulation protein YtfJ
KM416_10335	COG2226	methyltransferase
KM416_10360	COG0346	lactoylglutathione lyase activity
KM416_10370	COG0604	alcohol dehydrogenase
KM416_10375	COG1595	DNA-templated transcription, initiation
KM416_10400	COG0386	Belongs to the glutathione peroxidase family
KM416_10405	COG1305	Transglutaminase-like
KM416_10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM416_10415	COG0714	Associated with various cellular activities
KM416_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM416_10435	COG1140	nitrate reductase beta subunit
KM416_10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM416_10445	COG2181	nitrate reductase activity
KM416_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM416_10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM416_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM416_10480	COG0303	'Molybdopterin
KM416_10485	COG0314	molybdopterin synthase activity
KM416_10495	COG2223	nitrite transmembrane transporter activity
KM416_10510	COG1648	precorrin-2 dehydrogenase activity
KM416_10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM416_10520	COG1587	Uroporphyrinogen-III synthase
KM416_10525	COG2146	nitrite reductase [NAD(P)H] activity
KM416_10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM416_10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM416_10570	COG2359	stage V sporulation protein S
KM416_10585	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM416_10600	COG1418	mRNA catabolic process
KM416_10605	COG0488	(ABC) transporter
KM416_10620	COG0629	single-stranded DNA binding
KM416_10635	COG1413	lyase activity
KM416_10650	COG2136	Putative SAM-dependent methyltransferase
KM416_10650	COG2521	methyltransferase
KM416_10655	COG0018	arginyl-trna synthetase
KM416_10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM416_10700	COG0017	Asparaginyl-tRNA synthetase
KM416_10720	COG1674	ftsk spoiiie
KM416_10790	COG1929	Belongs to the glycerate kinase type-1 family
KM416_10795	COG0471	metal ion transport
KM416_10800	COG0745	RESPONSE REGULATOR receiver
KM416_10805	COG5002	protein histidine kinase activity
KM416_10805	COG3850	Histidine kinase
KM416_10820	COG0733	neurotransmitter:sodium symporter activity
KM416_10845	COG2610	gluconate transmembrane transporter activity
KM416_10850	COG1454	alcohol dehydrogenase
KM416_10855	COG1794	racemase activity, acting on amino acids and derivatives
KM416_10865	COG0456	acetyltransferase
KM416_10880	COG1131	(ABC) transporter
KM416_10895	COG0546	phosphoglycolate phosphatase activity
KM416_10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM416_10930	COG0768	penicillin binding
KM416_10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM416_10940	COG0204	Acyl-transferase
KM416_10945	COG1272	protein, Hemolysin III
KM416_10955	COG0805	protein transport
KM416_10965	COG1307	EDD domain protein, DegV family
KM416_10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM416_10975	COG1999	signal sequence binding
KM416_10980	COG0071	Belongs to the small heat shock protein (HSP20) family
KM416_10985	COG0367	asparagine synthase
KM416_11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM416_11030	COG1051	belongs to the nudix hydrolase family
KM416_11040	COG0668	transmembrane transport
KM416_11045	COG4585	Histidine kinase
KM416_11045	COG2203	Gaf domain
KM416_11050	COG2197	response regulator
KM416_11060	COG1064	alcohol dehydrogenase
KM416_11085	COG1070	Carbohydrate kinase
KM416_11090	COG1070	Carbohydrate kinase
KM416_11120	COG1125	glycine betaine transport
KM416_11120	COG0517	IMP dehydrogenase activity
KM416_11125	COG1174	glycine betaine transport
KM416_11160	COG1253	flavin adenine dinucleotide binding
KM416_11165	COG1012	belongs to the aldehyde dehydrogenase family
KM416_11170	COG5506	Protein of unknown function (DUF1694)
KM416_11185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM416_11190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM416_11195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM416_11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM416_11205	COG0456	acetyltransferase
KM416_11210	COG3829	transcription factor binding
KM416_11215	COG1509	lysine 2,3-aminomutase activity
KM416_11255	COG4326	sporulation control protein
KM416_11260	COG0671	phosphoesterase, PA-phosphatase related
KM416_11265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM416_11270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM416_11300	COG1715	Restriction endonuclease
KM416_11300	COG1787	Restriction endonuclease
KM416_11390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM416_11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM416_11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM416_11435	COG2814	Major facilitator Superfamily
KM416_11440	COG4841	protein insertion into membrane
KM416_11445	COG0372	Belongs to the citrate synthase family
KM416_11450	COG2079	MmgE PrpD family protein
KM416_11455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM416_11460	COG1960	acyl-CoA dehydrogenase activity
KM416_11465	COG2084	Dehydrogenase
KM416_11475	COG1280	lysine exporter protein (LysE YggA)
KM416_11480	COG1024	Enoyl-CoA hydratase
KM416_11495	COG0420	3'-5' exonuclease activity
KM416_11500	COG0419	ATPase involved in DNA repair
KM416_11520	COG2223	nitrite transmembrane transporter activity
KM416_11525	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_11530	COG1169	isochorismate synthase
KM416_11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM416_11540	COG1535	isochorismatase
KM416_11540	COG3433	isochorismatase activity
KM416_11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM416_11550	COG3251	PFAM MbtH domain protein
KM416_11555	COG2814	Major facilitator Superfamily
KM416_11570	COG0776	regulation of translation
KM416_11580	COG2318	DinB family
KM416_11590	COG1115	amino acid carrier protein
KM416_11605	COG2329	Antibiotic biosynthesis monooxygenase
KM416_11610	COG1187	pseudouridine synthase activity
KM416_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM416_11630	COG0596	Alpha beta hydrolase
KM416_11635	COG2814	Major facilitator Superfamily
KM416_11655	COG2226	methyltransferase
KM416_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_11735	COG1247	-acetyltransferase
KM416_11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM416_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_11785	COG1278	Cold shock
KM416_11800	COG0010	Belongs to the arginase family
KM416_11805	COG0561	phosphatase activity
KM416_11845	COG0583	DNA-binding transcription factor activity
KM416_11850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM416_11865	COG0583	DNA-binding transcription factor activity
KM416_11870	COG2258	MOSC domain
KM416_11885	COG1132	(ABC) transporter
KM416_11890	COG1132	(ABC) transporter
KM416_11910	COG1396	sequence-specific DNA binding
KM416_11935	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM416_11940	COG1595	DNA-templated transcription, initiation
KM416_11965	COG1649	PFAM Uncharacterised BCR, COG1649
KM416_11990	COG2971	BadF BadG BcrA BcrD
KM416_11995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM416_12000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM416_12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_12050	COG1309	transcriptional regulator
KM416_12065	COG0577	efflux transmembrane transporter activity
KM416_12065	COG1136	(ABC) transporter
KM416_12070	COG0500	methyltransferase
KM416_12070	COG3615	Tellurite resistance protein tehB
KM416_12080	COG2226	methyltransferase
KM416_12085	COG3961	Belongs to the TPP enzyme family
KM416_12090	COG1846	Transcriptional regulator
KM416_12130	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM416_12145	COG1595	DNA-templated transcription, initiation
KM416_12155	COG0768	penicillin binding
KM416_12165	COG2367	Beta-lactamase
KM416_12170	COG0671	phosphoesterase, PA-phosphatase related
KM416_12175	COG1609	Transcriptional regulator
KM416_12180	COG2814	Major facilitator Superfamily
KM416_12185	COG0673	inositol 2-dehydrogenase activity
KM416_12195	COG1012	belongs to the aldehyde dehydrogenase family
KM416_12210	COG0191	fructose-bisphosphate aldolase activity
KM416_12215	COG3718	enzyme involved in inositol metabolism
KM416_12240	COG0457	Tetratricopeptide repeat
KM416_12245	COG1476	TRANSCRIPTIONal
KM416_12260	COG1876	peptidase activity
KM416_12280	COG1309	transcriptional regulator
KM416_12285	COG0488	(ABC) transporter
KM416_12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_12315	COG1252	NADH dehydrogenase
KM416_12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_12335	COG1131	(ABC) transporter
KM416_12345	COG1309	transcriptional regulator
KM416_12360	COG1960	acyl-CoA dehydrogenase activity
KM416_12365	COG0439	Biotin carboxylase
KM416_12370	COG0511	ligase activity, forming carbon-carbon bonds
KM416_12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM416_12380	COG1024	Enoyl-CoA hydratase
KM416_12385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM416_12390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM416_12400	COG1247	-acetyltransferase
KM416_12405	COG0572	uridine kinase
KM416_12415	COG2318	DinB family
KM416_12420	COG1686	Belongs to the peptidase S11 family
KM416_12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM416_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM416_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM416_12510	COG2814	Major facilitator Superfamily
KM416_12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM416_12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_12565	COG1063	alcohol dehydrogenase
KM416_12595	COG3773	Cell wall hydrolase
KM416_12605	COG0745	RESPONSE REGULATOR receiver
KM416_12620	COG0488	(ABC) transporter
KM416_12635	COG1136	(ABC) transporter
KM416_12660	COG0460	homoserine dehydrogenase
KM416_12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM416_12740	COG2124	cytochrome p450
KM416_12775	COG0561	phosphatase activity
KM416_12785	COG5002	protein histidine kinase activity
KM416_12790	COG0768	penicillin binding
KM416_12795	COG1819	glycosyl
KM416_12800	COG1794	racemase activity, acting on amino acids and derivatives
KM416_12810	COG1122	ATPase activity
KM416_12825	COG2205	protein histidine kinase activity
KM416_12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM416_12840	COG0604	alcohol dehydrogenase
KM416_12845	COG0768	penicillin binding
KM416_12855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM416_12890	COG0693	protein deglycase activity
KM416_12920	COG2814	Major facilitator Superfamily
KM416_12935	COG0584	glycerophosphoryl diester phosphodiesterase
KM416_12955	COG0697	spore germination
KM416_12980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM416_12990	COG2223	nitrite transmembrane transporter activity
KM416_13005	COG2816	NAD+ diphosphatase activity
KM416_13010	COG0592	DNA-directed DNA polymerase activity
KM416_13015	COG1051	belongs to the nudix hydrolase family
KM416_13050	COG3878	Protein conserved in bacteria
KM416_13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM416_13110	COG0322	excinuclease ABC activity
KM416_13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM416_13175	COG1011	Hydrolase
KM416_13195	COG0076	glutamate decarboxylase activity
KM416_13210	COG1523	belongs to the glycosyl hydrolase 13 family
KM416_13215	COG3227	Zinc metalloprotease (Elastase)
KM416_13235	COG0201	protein transport
KM416_13245	COG0697	spore germination
KM416_13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_13280	COG4129	membrane
KM416_13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_13300	COG2959	enzyme of heme biosynthesis
KM416_13320	COG3483	tryptophan 2,3-dioxygenase activity
KM416_13325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM416_13330	COG3844	kynureninase activity
KM416_13335	COG1309	transcriptional regulator
KM416_13365	COG3284	Transcriptional regulator
KM416_13385	COG1349	DNA-binding transcription factor activity
KM416_13405	COG1959	2 iron, 2 sulfur cluster binding
KM416_13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM416_13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM416_13430	COG0022	dehydrogenase e1 component
KM416_13435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM416_13445	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_13450	COG0456	acetyltransferase
KM416_13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM416_13480	COG4176	ABC-type proline glycine betaine transport system permease component
KM416_13485	COG0517	IMP dehydrogenase activity
KM416_13485	COG4175	Glycine betaine
KM416_13510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM416_13515	COG2153	protein acetylation
KM416_13520	COG3397	chitin binding
KM416_13535	COG2205	protein histidine kinase activity
KM416_13560	COG0658	competence protein
KM416_13560	COG2333	competence protein COMEC
KM416_13610	COG3973	AAA domain
KM416_13625	COG2105	PFAM AIG2 family protein
KM416_13630	COG0514	ATP-dependent DNA helicase (RecQ)
KM416_13650	COG4637	Psort location Cytoplasmic, score
KM416_13675	COG3397	chitin binding
KM416_13690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM416_13695	COG1115	amino acid carrier protein
KM416_13700	COG1012	belongs to the aldehyde dehydrogenase family
KM416_13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM416_13715	COG3938	Belongs to the proline racemase family
KM416_13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM416_13760	COG0586	Pfam SNARE associated Golgi protein
KM416_13775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM416_13780	COG0519	Catalyzes the synthesis of GMP from XMP
KM416_13785	COG4166	transmembrane transport
KM416_13795	COG4948	Mandelate Racemase Muconate Lactonizing
KM416_13840	COG2936	dipeptidyl-peptidase activity
KM416_13845	COG5002	protein histidine kinase activity
KM416_13885	COG1164	Oligoendopeptidase f
KM416_13900	COG1307	EDD domain protein, DegV family
KM416_13920	COG2814	Major facilitator Superfamily
KM416_13930	COG1664	Polymer-forming cytoskeletal
KM416_13935	COG0789	Transcriptional regulator
KM416_13940	COG4533	DNA binding
KM416_13945	COG2814	Major facilitator Superfamily
KM416_13945	COG0477	Major facilitator Superfamily
KM416_13965	COG2261	transglycosylase associated protein
KM416_13980	COG2226	methyltransferase
KM416_14015	COG0436	Aminotransferase
KM416_14020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM416_14025	COG5146	pantothenate kinase activity
KM416_14045	COG1131	(ABC) transporter
KM416_14090	COG0628	permease
KM416_14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM416_14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM416_14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM416_14115	COG1116	anion transmembrane transporter activity
KM416_14135	COG2816	NAD+ diphosphatase activity
KM416_14155	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM416_14180	COG0697	spore germination
KM416_14185	COG2318	DinB family
KM416_14205	COG4912	Dna alkylation repair
KM416_14225	COG0861	Integral membrane protein TerC family
KM416_14230	COG1368	sulfuric ester hydrolase activity
KM416_14235	COG0488	(ABC) transporter
KM416_14245	COG1033	growth of symbiont in host cell
KM416_14245	COG2409	Drug exporters of the RND superfamily
KM416_14250	COG1033	growth of symbiont in host cell
KM416_14250	COG2409	Drug exporters of the RND superfamily
KM416_14255	COG2409	Drug exporters of the RND superfamily
KM416_14255	COG1033	growth of symbiont in host cell
KM416_14260	COG1309	transcriptional regulator
KM416_14275	COG0287	Prephenate dehydrogenase
KM416_14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM416_14285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM416_14290	COG1605	Chorismate mutase
KM416_14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM416_14325	COG3584	3D domain protein
KM416_14325	COG1388	LysM domain
KM416_14335	COG1595	DNA-templated transcription, initiation
KM416_14360	COG1879	ABC-type sugar transport system periplasmic component
KM416_14370	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM416_14380	COG2390	Transcriptional regulator
KM416_14415	COG2329	Antibiotic biosynthesis monooxygenase
KM416_14435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_14445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM416_14450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM416_14455	COG4187	Peptidase family M20/M25/M40
KM416_14460	COG1414	Transcriptional regulator
KM416_14465	COG0833	amino acid
KM416_14470	COG1690	Belongs to the RtcB family
KM416_14475	COG3239	Fatty acid desaturase
KM416_14480	COG1785	Belongs to the alkaline phosphatase family
KM416_14490	COG3655	Transcriptional regulator
KM416_14505	COG4377	Putative membrane peptidase family (DUF2324)
KM416_14515	COG3279	Response regulator of the LytR AlgR family
KM416_14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_14530	COG0346	lactoylglutathione lyase activity
KM416_14550	COG0714	Associated with various cellular activities
KM416_14575	COG0463	Glycosyl transferase, family 2
KM416_14600	COG0463	Glycosyl transferase, family 2
KM416_14610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM416_14615	COG0753	catalase activity
KM416_14625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM416_14650	COG0714	Associated with various cellular activities
KM416_14660	COG0778	Nitroreductase
KM416_14665	COG1846	Transcriptional regulator
KM416_14700	COG1725	Transcriptional regulator
KM416_14710	COG0577	efflux transmembrane transporter activity
KM416_14710	COG1136	(ABC) transporter
KM416_14735	COG2207	Transcriptional regulator
KM416_14740	COG0456	acetyltransferase
KM416_14760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_14780	COG0642	Histidine kinase
KM416_14785	COG0745	RESPONSE REGULATOR receiver
KM416_14790	COG0596	Alpha beta hydrolase
KM416_14820	COG0730	response to heat
KM416_14830	COG0833	amino acid
KM416_14840	COG4335	DNA alkylation repair
KM416_14880	COG0768	penicillin binding
KM416_14890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM416_14920	COG1984	allophanate hydrolase subunit 2
KM416_14925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM416_14930	COG1414	Transcriptional regulator
KM416_14945	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM416_14950	COG0640	Transcriptional regulator
KM416_14960	COG1960	acyl-CoA dehydrogenase activity
KM416_14975	COG3314	Sporulation integral membrane protein YlbJ
KM416_14990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM416_15005	COG0574	Belongs to the PEP-utilizing enzyme family
KM416_15005	COG3848	Pyruvate phosphate dikinase
KM416_15010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_15025	COG5577	PFAM Coat F domain
KM416_15030	COG3403	YqcI/YcgG family
KM416_15035	COG1280	lysine exporter protein (LysE YggA)
KM416_15070	COG1063	alcohol dehydrogenase
KM416_15085	COG1027	Aspartate ammonia-lyase
KM416_15090	COG0252	asparaginase activity
KM416_15095	COG1396	sequence-specific DNA binding
KM416_15105	COG0322	excinuclease ABC activity
KM416_15110	COG0531	amino acid
KM416_15115	COG1114	Component of the transport system for branched-chain amino acids
KM416_15120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM416_15130	COG0281	malic enzyme
KM416_15145	COG0531	amino acid
KM416_15155	COG0784	Response regulator, receiver
KM416_15165	COG2066	Belongs to the glutaminase family
KM416_15170	COG1115	amino acid carrier protein
KM416_15200	COG0737	Belongs to the 5'-nucleotidase family
KM416_15205	COG0753	catalase activity
KM416_15210	COG2267	carboxylic ester hydrolase activity
KM416_15215	COG1335	isochorismatase
KM416_15235	COG0583	DNA-binding transcription factor activity
KM416_15240	COG1846	Transcriptional regulator
KM416_15280	COG0415	Belongs to the DNA photolyase family
KM416_15285	COG0288	reversible hydration of carbon dioxide
KM416_15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM416_15300	COG5609	conserved protein (DUF2294)
KM416_15315	COG1575	Belongs to the MenA family. Type 1 subfamily
KM416_15320	COG2267	carboxylic ester hydrolase activity
KM416_15325	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM416_15330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM416_15335	COG1121	(ABC) transporter
KM416_15365	COG0798	PFAM Bile acid sodium symporter
KM416_15370	COG0346	lactoylglutathione lyase activity
KM416_15375	COG0640	Transcriptional regulator
KM416_15390	COG0443	Heat shock 70 kDa protein
KM416_15405	COG1522	sequence-specific DNA binding
KM416_15420	COG0346	lactoylglutathione lyase activity
KM416_15445	COG2169	Transcriptional regulator
KM416_15490	COG2814	Major facilitator Superfamily
KM416_15515	COG0745	RESPONSE REGULATOR receiver
KM416_15520	COG3850	Histidine kinase
KM416_15520	COG5002	protein histidine kinase activity
KM416_15545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM416_15565	COG1476	TRANSCRIPTIONal
KM416_15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_15585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM416_15595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_15600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM416_15615	COG1136	(ABC) transporter
KM416_15620	COG0577	efflux transmembrane transporter activity
KM416_15635	COG3850	Histidine kinase
KM416_15635	COG5002	protein histidine kinase activity
KM416_15645	COG2364	Membrane
KM416_15650	COG1846	Transcriptional regulator
KM416_15660	COG2808	Putative FMN-binding domain
KM416_15665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_15670	COG2271	Major facilitator Superfamily
KM416_15675	COG1556	Lactate utilization protein
KM416_15680	COG1139	Iron-sulfur cluster binding protein
KM416_15690	COG0583	DNA-binding transcription factor activity
KM416_15700	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM416_15720	COG0738	Major facilitator superfamily
KM416_15725	COG0673	inositol 2-dehydrogenase activity
KM416_15730	COG0561	phosphatase activity
KM416_15740	COG1609	Transcriptional regulator
KM416_15745	COG0457	Tetratricopeptide repeat
KM416_15765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM416_15795	COG0534	Mate efflux family protein
KM416_15815	COG2814	Major facilitator Superfamily
KM416_15820	COG1309	transcriptional regulator
KM416_15835	COG0814	amino acid
KM416_15840	COG1760	l-serine dehydratase
KM416_15845	COG1760	l-serine dehydratase
KM416_15855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM416_15860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM416_15870	COG1335	isochorismatase
KM416_15875	COG1522	sequence-specific DNA binding
KM416_15880	COG0531	amino acid
KM416_15895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM416_15915	COG1595	DNA-templated transcription, initiation
KM416_15930	COG0662	Cupin 2, conserved barrel domain protein
KM416_15935	COG2207	Transcriptional regulator
KM416_15935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_15985	COG0477	Major facilitator Superfamily
KM416_15995	COG1846	Transcriptional regulator
KM416_16000	COG2814	Major facilitator Superfamily
KM416_16010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM416_16015	COG1131	(ABC) transporter
KM416_16035	COG2076	Multidrug Resistance protein
KM416_16040	COG1309	transcriptional regulator
KM416_16050	COG2031	fatty acid transporter
KM416_16060	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM416_16090	COG1122	ATPase activity
KM416_16095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM416_16110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM416_16115	COG1288	antiporter activity
KM416_16120	COG2356	endonuclease I
KM416_16135	COG3620	sequence-specific DNA binding
KM416_16140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM416_16145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM416_16150	COG0124	histidyl-tRNA synthetase
KM416_16165	COG1733	regulation of RNA biosynthetic process
KM416_16170	COG0778	Nitroreductase
KM416_16190	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_16200	COG1131	(ABC) transporter
KM416_16225	COG1011	Hydrolase
KM416_16235	COG2365	Tyrosine phosphatase family
KM416_16260	COG0346	lactoylglutathione lyase activity
KM416_16265	COG1940	carbohydrate kinase activity
KM416_16270	COG0738	Major facilitator superfamily
KM416_16275	COG0110	maltose O-acetyltransferase activity
KM416_16285	COG0577	efflux transmembrane transporter activity
KM416_16285	COG1136	(ABC) transporter
KM416_16300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM416_16305	COG0628	permease
KM416_16325	COG2226	methyltransferase
KM416_16335	COG0477	Major facilitator Superfamily
KM416_16365	COG1253	flavin adenine dinucleotide binding
KM416_16370	COG0789	Transcriptional regulator
KM416_16375	COG0697	spore germination
KM416_16380	COG1357	PFAM Pentapeptide repeats (8 copies)
KM416_16385	COG3813	Protein conserved in bacteria
KM416_16390	COG2706	6-phosphogluconolactonase activity
KM416_16395	COG1070	Carbohydrate kinase
KM416_16405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM416_16410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM416_16420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM416_16425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM416_16430	COG0604	alcohol dehydrogenase
KM416_16435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM416_16445	COG3321	synthase
KM416_16445	COG0604	alcohol dehydrogenase
KM416_16450	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_16475	COG0656	L-ascorbic acid biosynthetic process
KM416_16480	COG2814	Major facilitator Superfamily
KM416_16495	COG0346	lactoylglutathione lyase activity
KM416_16500	COG0814	amino acid
KM416_16525	COG1393	Belongs to the ArsC family
KM416_16530	COG1733	regulation of RNA biosynthetic process
KM416_16535	COG2188	Transcriptional regulator
KM416_16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM416_16550	COG1733	regulation of RNA biosynthetic process
KM416_16555	COG1733	regulation of RNA biosynthetic process
KM416_16570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_16590	COG0384	phenazine biosynthesis protein PhzF
KM416_16600	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_16610	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_16620	COG1733	regulation of RNA biosynthetic process
KM416_16655	COG1191	sigma factor activity
KM416_16670	COG1309	transcriptional regulator
KM416_16690	COG3152	Membrane
KM416_16715	COG1151	hydroxylamine reductase activity
KM416_16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_16730	COG3757	hydrolase, family 25
KM416_16730	COG3409	Peptidoglycan-binding domain 1 protein
KM416_16765	COG2072	flavoprotein involved in K transport
KM416_16800	COG0604	alcohol dehydrogenase
KM416_16805	COG1113	amino acid transport
KM416_16810	COG2814	Major facilitator Superfamily
KM416_16840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM416_16845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM416_16865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_16880	COG3739	integral membrane protein
KM416_16885	COG0384	phenazine biosynthesis protein PhzF
KM416_16915	COG0583	DNA-binding transcription factor activity
KM416_16935	COG1193	negative regulation of DNA recombination
KM416_16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM416_16990	COG0584	glycerophosphoryl diester phosphodiesterase
KM416_17015	COG0640	Transcriptional regulator
KM416_17020	COG0604	alcohol dehydrogenase
KM416_17040	COG2808	Putative FMN-binding domain
KM416_17045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM416_17055	COG0385	Bile acid
KM416_17060	COG0277	FAD linked oxidase domain protein
KM416_17090	COG1216	Glycosyl transferase, family 2
KM416_17095	COG1024	Enoyl-CoA hydratase
KM416_17105	COG1285	pathogenesis
KM416_17120	COG2514	catechol 2,3-dioxygenase activity
KM416_17125	COG2720	vancomycin resistance protein
KM416_17165	COG0716	FMN binding
KM416_17195	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_17205	COG0165	Argininosuccinate lyase
KM416_17220	COG4145	pantothenate transmembrane transporter activity
KM416_17230	COG1012	belongs to the aldehyde dehydrogenase family
KM416_17235	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_17245	COG1657	PFAM Prenyltransferase squalene oxidase
KM416_17250	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM416_17255	COG2962	Rard protein
KM416_17260	COG3326	Membrane
KM416_17275	COG0489	protein tyrosine kinase activity
KM416_17285	COG0314	molybdopterin synthase activity
KM416_17290	COG0303	'Molybdopterin
KM416_17295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM416_17300	COG2116	formate transmembrane transporter activity
KM416_17310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM416_17315	COG5609	conserved protein (DUF2294)
KM416_17320	COG2427	Protein of unknown function (DUF1641)
KM416_17325	COG3383	formate dehydrogenase (NAD+) activity
KM416_17330	COG0697	spore germination
KM416_17370	COG2226	methyltransferase
KM416_17375	COG4166	transmembrane transport
KM416_17380	COG4166	transmembrane transport
KM416_17385	COG4166	transmembrane transport
KM416_17390	COG1301	dicarboxylic acid transport
KM416_17395	COG1316	TRANSCRIPTIONal
KM416_17405	COG1595	DNA-templated transcription, initiation
KM416_17425	COG1131	(ABC) transporter
KM416_17435	COG0673	inositol 2-dehydrogenase activity
KM416_17440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM416_17445	COG0187	DNA topoisomerase II activity
KM416_17450	COG1832	CoA-binding protein
KM416_17455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM416_17460	COG0745	RESPONSE REGULATOR receiver
KM416_17475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM416_17480	COG4841	protein insertion into membrane
KM416_17485	COG0824	Thioesterase
KM416_17515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM416_17525	COG2274	protein secretion by the type I secretion system
KM416_17530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM416_17570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM416_17585	COG0183	Belongs to the thiolase family
KM416_17590	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_17595	COG1268	BioY protein
KM416_17600	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_17650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_17660	COG5002	protein histidine kinase activity
KM416_17665	COG0400	carboxylic ester hydrolase activity
KM416_17670	COG0346	lactoylglutathione lyase activity
KM416_17675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM416_17680	COG0069	glutamate synthase activity
KM416_17685	COG1902	pentaerythritol trinitrate reductase activity
KM416_17690	COG1329	Transcriptional regulator
KM416_17695	COG0010	Belongs to the arginase family
KM416_17720	COG2226	methyltransferase
KM416_17775	COG4846	Membrane protein involved in cytochrome C biogenesis
KM416_17780	COG0785	Cytochrome C biogenesis protein
KM416_17790	COG0583	DNA-binding transcription factor activity
KM416_17795	COG1380	Effector of murein hydrolase LrgA
KM416_17800	COG1346	cytolysis
KM416_17825	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM416_17825	COG3409	Peptidoglycan-binding domain 1 protein
KM416_17840	COG1132	(ABC) transporter
KM416_17845	COG1132	(ABC) transporter
KM416_17875	COG3639	organic phosphonate transmembrane transporter activity
KM416_17880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM416_17900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM416_17920	COG1695	Transcriptional regulator
KM416_17955	COG1388	LysM domain
KM416_17955	COG3409	Peptidoglycan-binding domain 1 protein
KM416_17955	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM416_17960	COG4824	toxin secretion phage lysis holin
KM416_18115	COG1595	DNA-templated transcription, initiation
KM416_18160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM416_18240	COG1396	sequence-specific DNA binding
KM416_18265	COG0174	glutamine synthetase
KM416_18270	COG0789	Transcriptional regulator
KM416_18275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM416_18285	COG2860	membrane
KM416_18295	COG0464	growth
KM416_18325	COG3584	3D domain protein
KM416_18325	COG1388	LysM domain
KM416_18330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM416_18330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM416_18330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM416_18335	COG1105	Belongs to the carbohydrate kinase PfkB family
KM416_18340	COG1349	DNA-binding transcription factor activity
KM416_18350	COG2322	membrane
KM416_18360	COG1113	amino acid transport
KM416_18375	COG1408	metallophosphoesterase
KM416_18380	COG2116	formate transmembrane transporter activity
KM416_18390	COG2217	Heavy metal translocating P-type atpase
KM416_18395	COG2608	mercury ion transmembrane transporter activity
KM416_18400	COG1937	Protein conserved in bacteria
KM416_18410	COG2819	hydrolase of the alpha beta superfamily
KM416_18415	COG1120	ATPase activity
KM416_18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_18435	COG0708	Exodeoxyribonuclease III
KM416_18440	COG2169	Transcriptional regulator
KM416_18445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM416_18450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM416_18460	COG2364	Membrane
KM416_18475	COG2267	carboxylic ester hydrolase activity
KM416_18480	COG0346	lactoylglutathione lyase activity
KM416_18485	COG3300	MHYT domain
KM416_18485	COG5001	Diguanylate cyclase
KM416_18500	COG1346	cytolysis
KM416_18505	COG1380	Effector of murein hydrolase LrgA
KM416_18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM416_18515	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM416_18515	COG0596	Alpha beta hydrolase
KM416_18520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM416_18540	COG1404	Belongs to the peptidase S8 family
KM416_18545	COG3773	Cell wall hydrolase
KM416_18550	COG0562	UDP-galactopyranose mutase
KM416_18555	COG1368	sulfuric ester hydrolase activity
KM416_18560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM416_18570	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM416_18595	COG1131	(ABC) transporter
KM416_18615	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM416_18620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM416_18625	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM416_18630	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM416_18630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM416_18640	COG2359	stage V sporulation protein S
KM416_18645	COG1692	metallophosphoesterase
KM416_18670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM416_18675	COG1426	Protein conserved in bacteria
KM416_18690	COG0300	oxidoreductase activity
KM416_18695	COG0612	Peptidase, M16
KM416_18700	COG0612	Peptidase, M16
KM416_18705	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM416_18715	COG3845	ABC transporter
KM416_18720	COG1744	ABC transporter substrate-binding protein PnrA-like
KM416_18725	COG2188	Transcriptional regulator
KM416_18730	COG1674	ftsk spoiiie
KM416_18740	COG0740	serine-type endopeptidase activity
KM416_18745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM416_18755	COG0527	aspartate kinase activity
KM416_18760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM416_18765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM416_18770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM416_18775	COG1873	PFAM PRC-barrel domain
KM416_18780	COG0612	Peptidase, M16
KM416_18785	COG0726	polysaccharide deacetylase
KM416_18800	COG0196	riboflavin kinase activity
KM416_18805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM416_18815	COG1550	Protein conserved in bacteria
KM416_18825	COG1358	cellular component organization or biogenesis
KM416_18830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM416_18835	COG0195	Participates in both transcription termination and antitermination
KM416_18855	COG0750	zinc metalloprotease
KM416_18865	COG4589	Belongs to the CDS family
KM416_18870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM416_18880	COG0528	UMP kinase activity
KM416_18910	COG4974	Belongs to the 'phage' integrase family
KM416_18920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM416_18930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM416_18970	COG1837	Belongs to the UPF0109 family
KM416_18980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM416_18990	COG0552	protein localization to endoplasmic reticulum
KM416_18995	COG1196	nuclear chromosome segregation
KM416_19005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM416_19010	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_19015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM416_19030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM416_19035	COG1461	Dihydroxyacetone kinase
KM416_19040	COG1302	Protein conserved in bacteria
KM416_19055	COG1564	THIamine pyrophosphokinase
KM416_19060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM416_19065	COG1162	GTPase activity
KM416_19070	COG0515	serine threonine protein kinase
KM416_19070	COG2815	serine threonine protein kinase
KM416_19075	COG0631	protein serine/threonine phosphatase activity
KM416_19085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM416_19085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM416_19095	COG0242	peptide deformylase activity
KM416_19100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM416_19105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM416_19125	COG1561	YicC-like family, N-terminal region
KM416_19130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM416_19140	COG0006	proline dipeptidase activity
KM416_19155	COG3069	C4-dicarboxylate transmembrane transporter activity
KM416_19220	COG0564	pseudouridine synthase activity
KM416_19240	COG3599	regulation of cell shape
KM416_19245	COG2302	S4 RNA-binding domain
KM416_19250	COG0762	integral membrane protein
KM416_19260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM416_19265	COG1496	oxidoreductase activity
KM416_19270	COG1873	PFAM PRC-barrel domain
KM416_19275	COG1191	sigma factor activity
KM416_19280	COG1191	sigma factor activity
KM416_19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM416_19295	COG0849	cell division
KM416_19300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM416_19305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM416_19315	COG0772	Belongs to the SEDS family
KM416_19330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM416_19335	COG0768	penicillin binding
KM416_19340	COG0768	penicillin binding
KM416_19345	COG4839	cell division protein FtsL
KM416_19360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM416_19375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM416_19380	COG1399	metal-binding, possibly nucleic acid-binding protein
KM416_19430	COG4824	toxin secretion phage lysis holin
KM416_19515	COG1802	Transcriptional regulator
KM416_19515	COG4626	Terminase
KM416_19540	COG0582	viral genome integration into host DNA
KM416_19605	COG0756	dUTP diphosphatase activity
KM416_19620	COG1191	sigma factor activity
KM416_19645	COG1484	DNA-dependent DNA replication
KM416_19675	COG1396	sequence-specific DNA binding
KM416_19690	COG1396	sequence-specific DNA binding
KM416_19705	COG0582	viral genome integration into host DNA
KM416_19715	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM416_19720	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM416_19725	COG3314	Sporulation integral membrane protein YlbJ
KM416_19735	COG0742	ribosomal rna small subunit methyltransferase
KM416_19750	COG3679	Belongs to the UPF0342 family
KM416_19755	COG0406	alpha-ribazole phosphatase activity
KM416_19770	COG2340	Cysteine-rich secretory protein family
KM416_19785	COG3336	cytochrome c oxidase
KM416_19820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM416_19825	COG0772	Belongs to the SEDS family
KM416_19835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM416_19840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM416_19850	COG4896	Protein conserved in bacteria
KM416_19865	COG1217	gtp-binding protein TYPA
KM416_19875	COG0483	inositol monophosphate 1-phosphatase activity
KM416_19895	COG1982	Orn Lys Arg decarboxylase major
KM416_19940	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM416_19945	COG0022	dehydrogenase e1 component
KM416_19950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM416_19960	COG0242	peptide deformylase activity
KM416_19965	COG0561	phosphatase activity
KM416_19975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM416_19980	COG0569	domain protein
KM416_20000	COG0583	DNA-binding transcription factor activity
KM416_20005	COG0517	IMP dehydrogenase activity
KM416_20015	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM416_20025	COG4703	Protein of unknown function (DUF1797)
KM416_20040	COG2200	EAL domain
KM416_20045	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_20050	COG1408	metallophosphoesterase
KM416_20060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM416_20095	COG2814	Major facilitator Superfamily
KM416_20115	COG3209	COG3209 Rhs family protein
KM416_20125	COG2205	protein histidine kinase activity
KM416_20135	COG0436	Aminotransferase
KM416_20140	COG1609	Transcriptional regulator
KM416_20145	COG3833	ABC-type maltose transport systems, permease component
KM416_20150	COG1175	transmembrane transport
KM416_20155	COG2182	Extracellular solute-binding protein
KM416_20165	COG0366	Alpha amylase catalytic
KM416_20170	COG3842	ATPase activity
KM416_20210	COG0183	Belongs to the thiolase family
KM416_20245	COG1695	Transcriptional regulator
KM416_20250	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_20260	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM416_20270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM416_20275	COG0436	Aminotransferase
KM416_20295	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM416_20315	COG2199	diguanylate cyclase activity
KM416_20320	COG0778	Nitroreductase
KM416_20345	COG1263	PTS System
KM416_20345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM416_20345	COG2190	(PTS) system
KM416_20350	COG3711	transcriptional antiterminator
KM416_20360	COG2188	Transcriptional regulator
KM416_20370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM416_20395	COG1547	Domain of unknown function (DUF309)
KM416_20400	COG0456	acetyltransferase
KM416_20405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM416_20410	COG4086	secreted protein
KM416_20415	COG0561	phosphatase activity
KM416_20420	COG0697	spore germination
KM416_20435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_20460	COG0733	neurotransmitter:sodium symporter activity
KM416_20480	COG1686	Belongs to the peptidase S11 family
KM416_20485	COG1725	Transcriptional regulator
KM416_20490	COG1131	(ABC) transporter
KM416_20505	COG1846	Transcriptional regulator
KM416_20520	COG0598	Magnesium transport protein CorA
KM416_20545	COG4974	Belongs to the 'phage' integrase family
KM416_20555	COG0735	belongs to the Fur family
KM416_20560	COG1300	Membrane
KM416_20580	COG0667	Aldo Keto reductase
KM416_20585	COG0656	L-ascorbic acid biosynthetic process
KM416_20590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM416_20590	COG0456	acetyltransferase
KM416_20600	COG1525	nuclease
KM416_20600	COG4085	toxin activity
KM416_20600	COG0737	Belongs to the 5'-nucleotidase family
KM416_20610	COG0596	Alpha beta hydrolase
KM416_20615	COG2056	Na+-H+ antiporter family
KM416_20620	COG1609	Transcriptional regulator
KM416_20625	COG0456	acetyltransferase
KM416_20630	COG1073	alpha beta
KM416_20645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM416_20645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM416_20650	COG0307	riboflavin synthase, alpha
KM416_20675	COG4106	trans-aconitate 2-methyltransferase activity
KM416_20680	COG1073	alpha beta
KM416_20680	COG2226	methyltransferase
KM416_20695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM416_20705	COG1757	Na H antiporter
KM416_20710	COG0737	Belongs to the 5'-nucleotidase family
KM416_20720	COG1522	sequence-specific DNA binding
KM416_20740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM416_20750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM416_20765	COG0300	oxidoreductase activity
KM416_20775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM416_20780	COG1760	l-serine dehydratase
KM416_20785	COG1760	l-serine dehydratase
KM416_20805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM416_20815	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM416_20820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_20835	COG1376	ErfK ybiS ycfS ynhG family protein
KM416_20840	COG4129	membrane
KM416_20845	COG1126	abc transporter atp-binding protein
KM416_20850	COG0765	amino acid transport
KM416_20855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM416_20875	COG0772	Belongs to the SEDS family
KM416_20880	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM416_20885	COG0022	dehydrogenase e1 component
KM416_20890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM416_20895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM416_20910	COG0280	phosphate acetyltransferase
KM416_20915	COG3290	protein histidine kinase activity
KM416_20915	COG3829	transcription factor binding
KM416_20925	COG0584	glycerophosphoryl diester phosphodiesterase
KM416_20930	COG3093	addiction module antidote protein HigA
KM416_20940	COG0745	RESPONSE REGULATOR receiver
KM416_20945	COG0750	zinc metalloprotease
KM416_20950	COG0497	DNA recombination
KM416_20960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM416_20970	COG0142	geranyltranstransferase activity
KM416_20995	COG1302	Protein conserved in bacteria
KM416_21000	COG0439	Biotin carboxylase
KM416_21005	COG0511	ligase activity, forming carbon-carbon bonds
KM416_21050	COG3854	ATPases associated with a variety of cellular activities
KM416_21075	COG0006	proline dipeptidase activity
KM416_21090	COG3872	metal-dependent enzyme
KM416_21100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM416_21120	COG0095	Lipoate-protein ligase
KM416_21125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_21130	COG1609	Transcriptional regulator
KM416_21140	COG2076	Multidrug Resistance protein
KM416_21145	COG2076	Multidrug Resistance protein
KM416_21180	COG1131	(ABC) transporter
KM416_21185	COG1725	Transcriptional regulator
KM416_21215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM416_21270	COG4970	Tfp pilus assembly protein FimT
KM416_21280	COG1459	type II secretion system
KM416_21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM416_21335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM416_21340	COG1410	methionine synthase
KM416_21340	COG0646	methionine synthase
KM416_21345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM416_21345	COG0646	methionine synthase
KM416_21350	COG0626	cystathionine gamma-synthase activity
KM416_21355	COG0626	cystathionine gamma-synthase activity
KM416_21375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_21385	COG1940	carbohydrate kinase activity
KM416_21390	COG4483	Protein conserved in bacteria
KM416_21395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM416_21400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM416_21405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM416_21410	COG0704	Plays a role in the regulation of phosphate uptake
KM416_21420	COG0581	inorganic phosphate transmembrane transporter activity
KM416_21425	COG0573	inorganic phosphate transmembrane transporter activity
KM416_21430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM416_21435	COG0768	penicillin binding
KM416_21440	COG0477	Major facilitator Superfamily
KM416_21445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM416_21470	COG0735	belongs to the Fur family
KM416_21475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM416_21480	COG1121	(ABC) transporter
KM416_21485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_21515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM416_21520	COG2384	SAM-dependent methyltransferase
KM416_21525	COG2010	Cytochrome c
KM416_21530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM416_21535	COG0358	DNA primase activity
KM416_21545	COG0517	IMP dehydrogenase activity
KM416_21560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM416_21565	COG0295	cytidine deaminase activity
KM416_21570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM416_21580	COG1480	7TM receptor with intracellular HD hydrolase
KM416_21585	COG1702	phosphate starvation-inducible protein PhoH
KM416_21600	COG1610	YqeY-like protein
KM416_21605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM416_21610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM416_21615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM416_21645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM416_21650	COG1733	regulation of RNA biosynthetic process
KM416_21675	COG1466	dna polymerase III delta subunit
KM416_21685	COG0658	competence protein
KM416_21685	COG2333	competence protein COMEC
KM416_21690	COG2131	deaminase
KM416_21695	COG1596	polysaccharide export
KM416_21695	COG1555	photosystem II stabilization
KM416_21700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM416_21705	COG2226	methyltransferase
KM416_21710	COG0799	negative regulation of ribosome biogenesis
KM416_21725	COG1534	Rna-binding protein
KM416_21735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM416_21740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM416_21765	COG1595	DNA-templated transcription, initiation
KM416_21775	COG0778	Nitroreductase
KM416_21780	COG2357	RelA SpoT domain protein
KM416_21790	COG1785	Belongs to the alkaline phosphatase family
KM416_21800	COG2267	carboxylic ester hydrolase activity
KM416_21835	COG1404	Belongs to the peptidase S8 family
KM416_21840	COG3186	Phenylalanine-4-hydroxylase
KM416_21855	COG2259	Doxx family
KM416_21895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_21905	COG1454	alcohol dehydrogenase
KM416_21905	COG1012	belongs to the aldehyde dehydrogenase family
KM416_21910	COG0626	cystathionine gamma-synthase activity
KM416_21915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM416_21940	COG0768	penicillin binding
KM416_21955	COG0826	peptidase U32
KM416_21960	COG0826	peptidase U32
KM416_21965	COG4122	O-methyltransferase activity
KM416_21970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM416_21990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM416_22000	COG0628	permease
KM416_22020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM416_22030	COG0482	sulfurtransferase activity
KM416_22035	COG1104	cysteine desulfurase activity
KM416_22040	COG1959	2 iron, 2 sulfur cluster binding
KM416_22045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM416_22055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM416_22080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM416_22090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM416_22090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM416_22095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM416_22100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM416_22100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM416_22110	COG2244	polysaccharide biosynthetic process
KM416_22115	COG2323	membrane
KM416_22125	COG1862	Preprotein translocase
KM416_22155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM416_22165	COG0697	spore germination
KM416_22170	COG0697	spore germination
KM416_22175	COG0640	Transcriptional regulator
KM416_22200	COG0157	Belongs to the NadC ModD family
KM416_22205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM416_22210	COG1104	cysteine desulfurase activity
KM416_22215	COG1827	regulation of RNA biosynthetic process
KM416_22220	COG2258	MOSC domain
KM416_22225	COG0077	Prephenate dehydratase
KM416_22230	COG0577	efflux transmembrane transporter activity
KM416_22235	COG0577	efflux transmembrane transporter activity
KM416_22240	COG1136	(ABC) transporter
KM416_22250	COG0745	RESPONSE REGULATOR receiver
KM416_22255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM416_22260	COG3290	protein histidine kinase activity
KM416_22270	COG2868	ribosomal protein
KM416_22280	COG1530	ribonuclease E activity
KM416_22285	COG1994	Peptidase M50
KM416_22290	COG0739	heme binding
KM416_22295	COG2894	cell division
KM416_22315	COG1077	Cell shape determining protein MreB Mrl
KM416_22335	COG0285	dihydrofolate synthase activity
KM416_22340	COG0525	valine-tRNA ligase activity
KM416_22350	COG1388	LysM domain
KM416_22360	COG0113	porphobilinogen synthase activity
KM416_22365	COG1587	Uroporphyrinogen-III synthase
KM416_22375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM416_22385	COG1846	Transcriptional regulator
KM416_22390	COG1764	response to oxidative stress
KM416_22405	COG1067	ATP-dependent peptidase activity
KM416_22405	COG0470	DNA polymerase III
KM416_22450	COG0622	Phosphoesterase
KM416_22465	COG5401	PFAM Sporulation and spore germination
KM416_22485	COG1309	transcriptional regulator
KM416_22500	COG2197	response regulator
KM416_22505	COG2233	PERMEase
KM416_22515	COG0402	S-adenosylhomocysteine deaminase activity
KM416_22520	COG0402	S-adenosylhomocysteine deaminase activity
KM416_22530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM416_22540	COG0444	Belongs to the ABC transporter superfamily
KM416_22545	COG4608	Belongs to the ABC transporter superfamily
KM416_22550	COG3275	phosphorelay sensor kinase activity
KM416_22555	COG3279	Response regulator of the LytR AlgR family
KM416_22570	COG1983	PspC domain protein
KM416_22575	COG1396	sequence-specific DNA binding
KM416_22580	COG0697	spore germination
KM416_22590	COG1959	2 iron, 2 sulfur cluster binding
KM416_22595	COG1668	transmembrane transport
KM416_22600	COG4152	abc transporter atp-binding protein
KM416_22605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM416_22615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM416_22620	COG1876	peptidase activity
KM416_22625	COG0824	Thioesterase
KM416_22630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM416_22635	COG1053	succinate dehydrogenase
KM416_22640	COG2009	succinate dehydrogenase
KM416_22645	COG1719	4-vinyl reductase, 4VR
KM416_22655	COG3118	belongs to the thioredoxin family
KM416_22660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM416_22665	COG2086	electron transfer activity
KM416_22670	COG1024	Enoyl-CoA hydratase
KM416_22675	COG1309	transcriptional regulator
KM416_22680	COG0318	PFAM AMP-dependent synthetase and ligase
KM416_22700	COG2318	DinB family
KM416_22730	COG1131	(ABC) transporter
KM416_22735	COG2205	protein histidine kinase activity
KM416_22740	COG0745	RESPONSE REGULATOR receiver
KM416_22750	COG4895	conserved protein (DUF2196)
KM416_22755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM416_22770	COG4509	Sortase family
KM416_22775	COG1120	ATPase activity
KM416_22790	COG5386	Cell surface protein
KM416_22800	COG5386	Cell surface protein
KM416_22805	COG1114	Component of the transport system for branched-chain amino acids
KM416_22810	COG1187	pseudouridine synthase activity
KM416_22820	COG1796	DNA polymerase
KM416_22820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM416_22825	COG1286	toxin biosynthetic process
KM416_22870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM416_22880	COG1418	mRNA catabolic process
KM416_22905	COG2814	Major facilitator Superfamily
KM416_22910	COG1566	PFAM secretion protein HlyD family protein
KM416_22915	COG1309	transcriptional regulator
KM416_22920	COG1363	Peptidase, m42
KM416_22945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM416_22955	COG1484	DNA-dependent DNA replication
KM416_22960	COG3611	Membrane attachment protein
KM416_22970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM416_22975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM416_22980	COG0237	dephospho-CoA kinase activity
KM416_22985	COG1971	Probably functions as a manganese efflux pump
KM416_22995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM416_22995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM416_23000	COG5002	protein histidine kinase activity
KM416_23005	COG0745	RESPONSE REGULATOR receiver
KM416_23025	COG0538	isocitrate dehydrogenase activity
KM416_23030	COG0372	Belongs to the citrate synthase family
KM416_23040	COG0628	permease
KM416_23045	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM416_23070	COG1725	Transcriptional regulator
KM416_23075	COG0281	malic enzyme
KM416_23080	COG0587	DNA-directed DNA polymerase activity
KM416_23095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM416_23115	COG4109	DRTGG domain
KM416_23130	COG0006	proline dipeptidase activity
KM416_23165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_23170	COG0662	Cupin 2, conserved barrel domain protein
KM416_23180	COG1476	TRANSCRIPTIONal
KM416_23195	COG1028	Short-chain dehydrogenase reductase Sdr
KM416_23200	COG0589	response to stress
KM416_23240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_23260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM416_23265	COG0827	DNA restriction-modification system
KM416_23270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM416_23275	COG3874	Sporulation protein YtfJ
KM416_23290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM416_23300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM416_23315	COG1104	cysteine desulfurase activity
KM416_23325	COG0583	DNA-binding transcription factor activity
KM416_23330	COG0697	spore germination
KM416_23340	COG1956	GAF domain-containing protein
KM416_23345	COG0626	cystathionine gamma-synthase activity
KM416_23375	COG1595	DNA-templated transcription, initiation
KM416_23385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM416_23390	COG0454	-acetyltransferase
KM416_23395	COG0517	IMP dehydrogenase activity
KM416_23400	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM416_23410	COG0745	RESPONSE REGULATOR receiver
KM416_23420	COG0666	response to abiotic stimulus
KM416_23455	COG1609	Transcriptional regulator
KM416_23460	COG4851	CamS sex pheromone cAM373 precursor
KM416_23465	COG3118	belongs to the thioredoxin family
KM416_23475	COG2309	aminopeptidase activity
KM416_23495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_23510	COG1674	ftsk spoiiie
KM416_23520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM416_23525	COG4848	Belongs to the UPF0354 family
KM416_23530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM416_23535	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM416_23540	COG1363	Peptidase, m42
KM416_23550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_23565	COG0510	thiamine kinase activity
KM416_23570	COG1523	belongs to the glycosyl hydrolase 13 family
KM416_23585	COG1349	DNA-binding transcription factor activity
KM416_23590	COG1187	pseudouridine synthase activity
KM416_23595	COG2244	polysaccharide biosynthetic process
KM416_23600	COG2081	HI0933 family
KM416_23605	COG2814	Major facilitator Superfamily
KM416_23615	COG3832	glyoxalase III activity
KM416_23635	COG1329	Transcriptional regulator
KM416_23645	COG4975	Glucose uptake
KM416_23660	COG0314	molybdopterin synthase activity
KM416_23665	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM416_23670	COG0303	'Molybdopterin
KM416_23680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM416_23705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM416_23715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM416_23755	COG2814	Major facilitator Superfamily
KM416_23760	COG0475	glutathione-regulated potassium exporter activity
KM416_23765	COG0490	domain, Protein
KM416_23770	COG0582	viral genome integration into host DNA
KM416_23780	COG1136	(ABC) transporter
KM416_23800	COG1242	4 iron, 4 sulfur cluster binding
KM416_23805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM416_23810	COG1131	(ABC) transporter
KM416_23820	COG1794	racemase activity, acting on amino acids and derivatives
KM416_23840	COG2267	carboxylic ester hydrolase activity
KM416_23850	COG0671	phosphoesterase, PA-phosphatase related
KM416_23855	COG0438	transferase activity, transferring glycosyl groups
KM416_23865	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM416_23920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM416_23925	COG5002	protein histidine kinase activity
KM416_23930	COG4191	Histidine kinase
KM416_23935	COG2267	carboxylic ester hydrolase activity
KM416_23955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM416_23960	COG1116	anion transmembrane transporter activity
KM416_23965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM416_23990	COG0494	nUDIX hydrolase
KM416_24020	COG0288	reversible hydration of carbon dioxide
KM416_24025	COG1271	oxidase subunit
KM416_24030	COG1294	oxidase, subunit
KM416_24050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_24075	COG1842	Phage shock protein A
KM416_24105	COG5002	protein histidine kinase activity
KM416_24110	COG0745	RESPONSE REGULATOR receiver
KM416_24140	COG1597	lipid kinase activity
KM416_24175	COG0586	Pfam SNARE associated Golgi protein
KM416_24185	COG0577	efflux transmembrane transporter activity
KM416_24190	COG1136	(ABC) transporter
KM416_24195	COG3708	Transcriptional regulator
KM416_24195	COG2207	Transcriptional regulator
KM416_24200	COG0745	RESPONSE REGULATOR receiver
KM416_24205	COG2205	protein histidine kinase activity
KM416_24210	COG0577	efflux transmembrane transporter activity
KM416_24220	COG0577	efflux transmembrane transporter activity
KM416_24225	COG1136	(ABC) transporter
KM416_24245	COG2188	Transcriptional regulator
KM416_24265	COG3964	amidohydrolase
KM416_24295	COG4948	Mandelate Racemase Muconate Lactonizing
KM416_24305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM416_24310	COG0596	Alpha beta hydrolase
KM416_24315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM416_24320	COG1169	isochorismate synthase
KM416_24325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM416_24330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM416_24350	COG0058	SHG alpha-glucan phosphorylase activity
KM416_24355	COG0297	glycogen (starch) synthase activity
KM416_24360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM416_24480	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM416_24515	COG1285	pathogenesis
KM416_24520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM416_24530	COG0166	Belongs to the GPI family
KM416_24535	COG2155	Conserved Protein
KM416_24540	COG1098	S1 RNA binding domain
KM416_24545	COG0436	Aminotransferase
KM416_24550	COG1522	sequence-specific DNA binding
KM416_24555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM416_24560	COG2267	carboxylic ester hydrolase activity
KM416_24570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM416_24590	COG5018	Exonuclease
KM416_24595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM416_24615	COG2050	protein possibly involved in aromatic compounds catabolism
KM416_24625	COG1268	BioY protein
KM416_24635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM416_24640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM416_24655	COG3584	3D domain protein
KM416_24670	COG1252	NADH dehydrogenase
KM416_24685	COG3708	Transcriptional regulator
KM416_24700	COG1683	Conserved Protein
KM416_24720	COG0316	Belongs to the HesB IscA family
KM416_24735	COG1252	NADH dehydrogenase
KM416_24750	COG0390	transport system, permease component
KM416_24755	COG2824	Alkylphosphonate utilization operon protein PhnA
KM416_24795	COG4837	Protein of unknown function (DUF1462)
KM416_24800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM416_24810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM416_24815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM416_24825	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM416_24830	COG0647	UMP catabolic process
KM416_24840	COG2445	Protein of unknown function DUF86
KM416_24845	COG1494	fructose-1,6-bisphosphatase
KM416_24860	COG4470	Protein conserved in bacteria
KM416_24870	COG0789	Transcriptional regulator
KM416_24875	COG4377	Putative membrane peptidase family (DUF2324)
KM416_24900	COG0739	heme binding
KM416_24910	COG3377	Domain of unknown function (DUF1805)
KM416_24915	COG0737	Belongs to the 5'-nucleotidase family
KM416_24920	COG1695	Transcriptional regulator
KM416_24930	COG0719	Fe-S assembly protein
KM416_24935	COG0822	iron-sulfur transferase activity
KM416_24940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM416_24945	COG0719	Fe-S assembly protein
KM416_24950	COG0396	ATPase activity
KM416_24955	COG1464	Belongs to the NlpA lipoprotein family
KM416_24960	COG1464	Belongs to the NlpA lipoprotein family
KM416_24965	COG2011	ABC-type metal ion transport system permease component
KM416_24970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM416_24980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM416_24985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM416_24995	COG1393	Belongs to the ArsC family
KM416_25040	COG0039	L-malate dehydrogenase activity
KM416_25060	COG1309	transcriptional regulator
KM416_25065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM416_25070	COG1960	acyl-CoA dehydrogenase activity
KM416_25075	COG0183	Belongs to the thiolase family
KM416_25080	COG1024	Enoyl-CoA hydratase
KM416_25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM416_25090	COG1686	Belongs to the peptidase S11 family
KM416_25105	COG0011	TIGRFAM Protein of
KM416_25110	COG0840	transmembrane signaling receptor activity
KM416_25130	COG2814	Major facilitator Superfamily
KM416_25135	COG0531	amino acid
KM416_25145	COG0706	membrane insertase activity
KM416_25155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM416_25190	COG0586	Pfam SNARE associated Golgi protein
KM416_25200	COG1376	ErfK ybiS ycfS ynhG family protein
KM416_25205	COG0745	RESPONSE REGULATOR receiver
KM416_25210	COG5002	protein histidine kinase activity
KM416_25235	COG2151	metal-sulfur cluster biosynthetic enzyme
KM416_25240	COG3227	Zinc metalloprotease (Elastase)
KM416_25245	COG1741	Belongs to the pirin family
KM416_25260	COG0475	glutathione-regulated potassium exporter activity
KM416_25265	COG0490	domain, Protein
KM416_25270	COG1115	amino acid carrier protein
KM416_25275	COG0783	Belongs to the Dps family
KM416_25290	COG1611	Belongs to the LOG family
KM416_25310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_25320	COG1115	amino acid carrier protein
KM416_25325	COG1115	amino acid carrier protein
KM416_25330	COG2910	NAD(P)H-binding
KM416_25345	COG0656	L-ascorbic acid biosynthetic process
KM416_25350	COG2814	Major facilitator Superfamily
KM416_25355	COG1733	regulation of RNA biosynthetic process
KM416_25365	COG1252	NADH dehydrogenase
KM416_25370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM416_25375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM416_25385	COG0840	transmembrane signaling receptor activity
KM416_25385	COG3290	protein histidine kinase activity
KM416_25395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM416_25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM416_25415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM416_25470	COG0557	exoribonuclease II activity
KM416_25475	COG1647	Serine aminopeptidase, S33
KM416_25480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM416_25485	COG1346	cytolysis
KM416_25585	COG4695	Portal protein
KM416_25610	COG4974	Belongs to the 'phage' integrase family
KM416_25620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM416_25625	COG0149	triose-phosphate isomerase activity
KM416_25635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM416_25650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM416_25675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM416_25690	COG2323	membrane
KM416_25695	COG0740	serine-type endopeptidase activity
KM416_25700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM416_25710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM416_25720	COG1051	belongs to the nudix hydrolase family
KM416_25730	COG0492	ferredoxin-NADP+ reductase activity
KM416_25735	COG0457	Tetratricopeptide repeat
KM416_25740	COG0110	maltose O-acetyltransferase activity
KM416_25760	COG1950	PFAM Membrane protein of
KM416_25770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM416_25775	COG0556	nucleotide-excision repair
KM416_25795	COG0789	Transcriptional regulator
KM416_25820	COG2855	membrane
KM416_25825	COG0583	DNA-binding transcription factor activity
KM416_25835	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM416_25840	COG0488	(ABC) transporter
KM416_25850	COG1132	(ABC) transporter
KM416_25855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM416_25860	COG0793	Belongs to the peptidase S41A family
KM416_25860	COG3409	Peptidoglycan-binding domain 1 protein
KM416_25865	COG2177	Part of the ABC transporter FtsEX involved in
KM416_25870	COG2884	Cell division ATP-binding protein ftsE
KM416_25885	COG0653	protein targeting
KM416_25890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM416_25895	COG1278	Cold shock
KM416_25900	COG1040	competence protein
KM416_25905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM416_25910	COG0791	NLP P60 protein
KM416_25910	COG1388	LysM domain
KM416_25915	COG1733	regulation of RNA biosynthetic process
KM416_25920	COG1307	EDD domain protein, DegV family
KM416_25925	COG1739	Uncharacterized protein family UPF0029
KM416_25930	COG1316	TRANSCRIPTIONal
KM416_25935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM416_25940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM416_25945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM416_25955	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM416_25955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM416_25970	COG3394	polysaccharide catabolic process
KM416_25975	COG1486	melibiose metabolic process
KM416_25980	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM416_25985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM416_25995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM416_26000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM416_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM416_26015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM416_26020	COG1301	dicarboxylic acid transport
KM416_26030	COG0346	lactoylglutathione lyase activity
KM416_26035	COG1511	domain protein
KM416_26040	COG0583	DNA-binding transcription factor activity
KM416_26045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM416_26060	COG1271	oxidase subunit
KM416_26065	COG1294	oxidase, subunit
KM416_26070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM416_26090	COG2389	metal-binding protein
KM416_26100	COG1368	sulfuric ester hydrolase activity
KM416_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM416_26125	COG1215	transferase activity, transferring glycosyl groups
KM416_26130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM416_26135	COG1388	LysM domain
KM416_26135	COG3584	3D domain protein
KM416_26160	COG4715	Zinc finger, swim domain protein
KM416_26165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM416_26205	COG0577	efflux transmembrane transporter activity
KM416_26210	COG1136	(ABC) transporter
KM416_26245	COG5002	protein histidine kinase activity
KM416_26250	COG0745	RESPONSE REGULATOR receiver
KM416_26255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM416_26270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM416_26275	COG1134	teichoic acid transport
KM416_26280	COG1682	transport, permease protein
KM416_26285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM416_26330	COG1609	Transcriptional regulator
KM416_26345	COG0739	heme binding
KM416_26365	COG2385	sporulation resulting in formation of a cellular spore
KM416_26380	COG4836	Membrane
KM416_26385	COG1007	ATP synthesis coupled electron transport
KM416_26390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM416_26395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM416_26405	COG0839	Belongs to the complex I subunit 6 family
KM416_26420	COG0649	NAD binding
KM416_26425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM416_26440	COG3300	MHYT domain
KM416_26440	COG5001	Diguanylate cyclase
KM416_26490	COG0356	it plays a direct role in the translocation of protons across the membrane
KM416_26525	COG0698	ribose 5-phosphate isomerase
KM416_26535	COG2190	(PTS) system
KM416_26540	COG2259	Doxx family
KM416_26545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM416_26560	COG0009	L-threonylcarbamoyladenylate synthase
KM416_26575	COG2890	protein-(glutamine-N5) methyltransferase activity
KM416_26595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM416_26600	COG1494	fructose-1,6-bisphosphatase
KM416_26620	COG4821	SIS domain
KM416_26630	COG3343	RNA polymerase activity
KM416_26640	COG1960	acyl-CoA dehydrogenase activity
KM416_26645	COG1960	acyl-CoA dehydrogenase activity
KM416_26650	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM416_26655	COG0183	Belongs to the thiolase family
KM416_26660	COG2181	nitrate reductase activity
KM416_26660	COG0247	lactate metabolic process
KM416_26665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM416_26675	COG3300	MHYT domain
KM416_26675	COG5001	Diguanylate cyclase
KM416_26695	COG2197	response regulator
KM416_26700	COG4585	Histidine kinase
KM416_26705	COG0842	Transport permease protein
KM416_26710	COG1131	(ABC) transporter
KM416_26715	COG0024	Methionine aminopeptidase
KM416_26725	COG2234	aminopeptidase activity
KM416_26745	COG1595	DNA-templated transcription, initiation
KM416_26750	COG0018	arginyl-trna synthetase
KM416_26755	COG4506	Protein conserved in bacteria
KM416_26760	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM416_26775	COG0010	Belongs to the arginase family
KM416_26785	COG2814	Major facilitator Superfamily
KM416_26790	COG0789	Transcriptional regulator
KM416_26795	COG0584	glycerophosphoryl diester phosphodiesterase
KM416_26800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM416_26810	COG1994	Peptidase M50
KM416_26820	COG1078	dGTPase activity
KM416_26825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM416_26830	COG1120	ATPase activity
KM416_26835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM416_26860	COG0095	Lipoate-protein ligase
KM416_26865	COG0280	phosphate acetyltransferase
KM416_26880	COG3773	Cell wall hydrolase
KM416_26890	COG2363	Small membrane protein
KM416_26900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM416_26905	COG2233	PERMEase
KM416_26910	COG0561	phosphatase activity
KM416_26915	COG2814	Major facilitator Superfamily
KM416_26925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM416_26930	COG1131	(ABC) transporter
KM416_26935	COG2755	lipolytic protein G-D-S-L family
KM416_26940	COG1609	Transcriptional regulator
KM416_26950	COG0460	homoserine dehydrogenase
KM416_26960	COG2873	o-acetylhomoserine
KM416_26970	COG1011	Hydrolase
KM416_26975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM416_26985	COG2197	response regulator
KM416_26995	COG0351	phosphomethylpyrimidine kinase
KM416_27000	COG3706	GGDEF domain
KM416_27005	COG2879	small protein
KM416_27010	COG1966	Carbon starvation protein
KM416_27015	COG3279	Response regulator of the LytR AlgR family
KM416_27020	COG0477	Major facilitator Superfamily
KM416_27045	COG0840	transmembrane signaling receptor activity
KM416_27055	COG1607	acyl-coa hydrolase
KM416_27070	COG0488	(ABC) transporter
KM416_27090	COG0463	Glycosyl transferase, family 2
KM416_27095	COG1309	transcriptional regulator
KM416_27100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM416_27105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM416_27105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM416_27110	COG0628	permease
KM416_27125	COG3279	Response regulator of the LytR AlgR family
KM416_27130	COG3275	phosphorelay sensor kinase activity
KM416_27135	COG2814	Major facilitator Superfamily
KM416_27140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM416_27145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM416_27150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM416_27170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM416_27175	COG1272	protein, Hemolysin III
KM416_27195	COG0516	GMP reductase activity
KM416_27200	COG1164	Oligoendopeptidase f
KM416_27220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM416_27225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM416_27230	COG4853	Protein conserved in bacteria
KM416_27235	COG4863	YycH protein
KM416_27240	COG5002	protein histidine kinase activity
KM416_27245	COG0745	RESPONSE REGULATOR receiver
KM416_27275	COG0305	Participates in initiation and elongation during chromosome replication
KM416_27285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM416_27290	COG4241	membrane
KM416_27300	COG0629	single-stranded DNA binding
KM416_27310	COG0012	GTP binding
KM416_27315	COG4481	Protein conserved in bacteria
KM416_27320	COG0668	transmembrane transport
KM416_27330	COG1475	DNA binding
KM416_27335	COG1192	Involved in chromosome partitioning
KM416_27360	COG1847	R3H domain protein
KM416_27365	COG0706	membrane insertase activity
KM416_27375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM416_27425	COG3344	reverse transcriptase
KM416_27505	COG3344	reverse transcriptase
KM416_27695	COG4962	Type ii secretion system protein e
KM416_27830	COG2311	Membrane
KM416_27850	COG4196	transglutaminase domain protein
KM416_27855	COG0671	phosphoesterase, PA-phosphatase related
KM416_27870	COG1215	transferase activity, transferring glycosyl groups
KM416_27875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM416_27880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM416_28040	COG2002	toxin-antitoxin pair type II binding
KM416_28050	COG4974	Belongs to the 'phage' integrase family
KM416_28105	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM416_28115	COG4974	Belongs to the 'phage' integrase family
KM416_28140	COG0457	Tetratricopeptide repeat
KM416_28345	COG0791	NLP P60 protein
KM416_28345	COG0741	lytic transglycosylase activity
KM416_28410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM416_28470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM416_28480	COG4166	transmembrane transport
KM416_28520	COG1280	lysine exporter protein (LysE YggA)
KM416_28545	COG0681	Belongs to the peptidase S26 family
KM416_28620	COG1309	transcriptional regulator
KM416_28625	COG1683	Conserved Protein
KM416_28665	COG1192	Involved in chromosome partitioning