locus-tag	class	description
KM387_00010	COG0592	DNA-directed DNA polymerase activity
KM387_00015	COG2501	S4 domain
KM387_00025	COG0187	DNA topoisomerase II activity
KM387_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM387_00065	COG0516	GMP reductase activity
KM387_00065	COG0517	IMP dehydrogenase activity
KM387_00070	COG1686	Belongs to the peptidase S11 family
KM387_00100	COG1428	Deoxynucleoside kinase
KM387_00105	COG1428	Deoxynucleoside kinase
KM387_00110	COG1335	isochorismatase
KM387_00115	COG0590	tRNA wobble adenosine to inosine editing
KM387_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM387_00180	COG1982	Orn Lys Arg decarboxylase major
KM387_00190	COG0470	DNA polymerase III
KM387_00195	COG1774	PSP1 C-terminal conserved region
KM387_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM387_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM387_00220	COG2002	toxin-antitoxin pair type II binding
KM387_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_00230	COG0084	hydrolase, TatD family'
KM387_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM387_00250	COG4466	Protein conserved in bacteria
KM387_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM387_00270	COG0251	oxidation-reduction process
KM387_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM387_00305	COG2002	toxin-antitoxin pair type II binding
KM387_00310	COG2244	polysaccharide biosynthetic process
KM387_00315	COG3956	TIGRFAM MazG family protein
KM387_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM387_00340	COG1098	S1 RNA binding domain
KM387_00355	COG2208	phosphoserine phosphatase activity
KM387_00360	COG0037	tRNA processing
KM387_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM387_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM387_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM387_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM387_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM387_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM387_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM387_00420	COG1396	sequence-specific DNA binding
KM387_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM387_00455	COG3880	PFAM UvrB UvrC protein
KM387_00465	COG0542	response to heat
KM387_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM387_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM387_00500	COG1045	serine acetyltransferase
KM387_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM387_00520	COG3688	RNA-binding protein containing a PIN domain
KM387_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM387_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM387_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM387_00565	COG2813	Specifically methylates the guanine in position
KM387_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM387_00580	COG1358	cellular component organization or biogenesis
KM387_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM387_00710	COG0201	protein transport
KM387_00720	COG0024	Methionine aminopeptidase
KM387_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM387_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM387_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_00795	COG0489	protein tyrosine kinase activity
KM387_00805	COG2194	sulfuric ester hydrolase activity
KM387_00810	COG0726	polysaccharide deacetylase
KM387_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM387_00895	COG4856	YbbR-like protein
KM387_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM387_00915	COG0596	Alpha beta hydrolase
KM387_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM387_00940	COG4946	Tricorn protease homolog
KM387_00940	COG1506	peptidase
KM387_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM387_00970	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_00975	COG2011	ABC-type metal ion transport system permease component
KM387_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_00985	COG1464	Belongs to the NlpA lipoprotein family
KM387_00990	COG0604	alcohol dehydrogenase
KM387_01000	COG0277	FAD linked oxidase domain protein
KM387_01005	COG2271	Major facilitator Superfamily
KM387_01015	COG2814	Major facilitator Superfamily
KM387_01030	COG0601	transmembrane transport
KM387_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_01040	COG0444	Belongs to the ABC transporter superfamily
KM387_01045	COG4608	Belongs to the ABC transporter superfamily
KM387_01050	COG4166	transmembrane transport
KM387_01060	COG2207	Transcriptional regulator
KM387_01075	COG4166	transmembrane transport
KM387_01080	COG4166	transmembrane transport
KM387_01085	COG0656	L-ascorbic acid biosynthetic process
KM387_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_01105	COG4149	molybdate abc transporter
KM387_01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM387_01115	COG1910	domain protein
KM387_01130	COG0697	spore germination
KM387_01145	COG0204	Acyl-transferase
KM387_01155	COG1609	Transcriptional regulator
KM387_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_01175	COG0084	hydrolase, TatD family'
KM387_01180	COG5298	Protein conserved in bacteria
KM387_01205	COG0488	(ABC) transporter
KM387_01220	COG0747	negative chemotaxis
KM387_01225	COG0601	transmembrane transport
KM387_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_01235	COG0444	Belongs to the ABC transporter superfamily
KM387_01240	COG4608	Belongs to the ABC transporter superfamily
KM387_01245	COG0561	phosphatase activity
KM387_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM387_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM387_01290	COG2814	Major facilitator Superfamily
KM387_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM387_01310	COG4294	response to UV
KM387_01315	COG0705	Rhomboid family
KM387_01315	COG0457	Tetratricopeptide repeat
KM387_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM387_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM387_01335	COG0864	Transcriptional regulator
KM387_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM387_01345	COG2183	response to ionizing radiation
KM387_01440	COG0802	atpase or kinase
KM387_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM387_01450	COG0456	acetyltransferase
KM387_01460	COG0488	(ABC) transporter
KM387_01475	COG1266	CAAX protease self-immunity
KM387_01495	COG2252	PERMEase
KM387_01505	COG5002	protein histidine kinase activity
KM387_01535	COG2226	methyltransferase
KM387_01545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_01575	COG1968	undecaprenyl-diphosphatase activity
KM387_01590	COG2205	protein histidine kinase activity
KM387_01595	COG0745	RESPONSE REGULATOR receiver
KM387_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM387_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM387_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM387_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM387_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM387_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM387_01670	COG0151	Belongs to the GarS family
KM387_01695	COG0210	DNA helicase
KM387_01705	COG4851	CamS sex pheromone cAM373 precursor
KM387_01725	COG1335	isochorismatase
KM387_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_01735	COG2011	ABC-type metal ion transport system permease component
KM387_01740	COG1464	Belongs to the NlpA lipoprotein family
KM387_01755	COG0003	Pfam Anion-transporting ATPase
KM387_01760	COG1846	Transcriptional regulator
KM387_01765	COG4682	membrane
KM387_01785	COG1597	lipid kinase activity
KM387_01790	COG0546	phosphoglycolate phosphatase activity
KM387_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM387_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM387_01810	COG2076	Multidrug Resistance protein
KM387_01815	COG2309	aminopeptidase activity
KM387_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM387_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM387_01850	COG4807	Protein conserved in bacteria
KM387_01875	COG1757	Na H antiporter
KM387_01880	COG1473	amidohydrolase
KM387_01895	COG0450	alkyl hydroperoxide reductase
KM387_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_01940	COG0166	Belongs to the GPI family
KM387_01975	COG5002	protein histidine kinase activity
KM387_01995	COG3541	Predicted nucleotidyltransferase
KM387_02000	COG2814	Major facilitator Superfamily
KM387_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM387_02015	COG0765	amino acid transport
KM387_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_02030	COG0840	transmembrane signaling receptor activity
KM387_02035	COG0840	transmembrane signaling receptor activity
KM387_02040	COG0366	Alpha amylase catalytic
KM387_02045	COG2190	(PTS) system
KM387_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_02045	COG1263	PTS System
KM387_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM387_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_02100	COG1116	anion transmembrane transporter activity
KM387_02105	COG0488	(ABC) transporter
KM387_02150	COG2270	Major facilitator Superfamily
KM387_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM387_02180	COG2310	stress, protein
KM387_02185	COG2310	stress, protein
KM387_02190	COG2310	stress, protein
KM387_02195	COG0861	Integral membrane protein TerC family
KM387_02205	COG3853	Toxic anion resistance protein (TelA)
KM387_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM387_02230	COG1295	ribonuclease BN
KM387_02235	COG2217	Heavy metal translocating P-type atpase
KM387_02240	COG0697	spore germination
KM387_02260	COG0586	Pfam SNARE associated Golgi protein
KM387_02275	COG3871	stress protein (general stress protein 26)
KM387_02280	COG0387	Pfam Sodium calcium exchanger
KM387_02290	COG0535	radical SAM domain protein
KM387_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM387_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM387_02325	COG0582	viral genome integration into host DNA
KM387_02335	COG1396	sequence-specific DNA binding
KM387_02350	COG1396	sequence-specific DNA binding
KM387_02385	COG1484	DNA-dependent DNA replication
KM387_02485	COG0582	viral genome integration into host DNA
KM387_02615	COG0101	tRNA pseudouridine synthase activity
KM387_02625	COG3829	transcription factor binding
KM387_02635	COG0833	amino acid
KM387_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_02670	COG1263	PTS System
KM387_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_02690	COG0463	Glycosyl transferase, family 2
KM387_02695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM387_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM387_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM387_02745	COG1228	amidohydrolase
KM387_02750	COG1090	epimerase
KM387_02780	COG1988	membrane-bound metal-dependent
KM387_02785	COG1194	a g-specific adenine glycosylase
KM387_02810	COG1132	(ABC) transporter
KM387_02815	COG4129	membrane
KM387_02820	COG0070	glutamate synthase
KM387_02820	COG0067	glutamate synthase
KM387_02820	COG0069	glutamate synthase activity
KM387_02830	COG4555	ABC transporter
KM387_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM387_02855	COG0735	belongs to the Fur family
KM387_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM387_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM387_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM387_03005	COG2766	serine protein kinase
KM387_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM387_03040	COG2268	Band 7 protein
KM387_03050	COG3290	protein histidine kinase activity
KM387_03055	COG4565	transcriptional regulatory protein
KM387_03060	COG2851	Citrate transporter
KM387_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM387_03085	COG3842	ATPase activity
KM387_03090	COG1175	transmembrane transport
KM387_03095	COG0395	ABC-type sugar transport system, permease component
KM387_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM387_03110	COG0745	RESPONSE REGULATOR receiver
KM387_03115	COG5002	protein histidine kinase activity
KM387_03125	COG4990	cell redox homeostasis
KM387_03135	COG3290	protein histidine kinase activity
KM387_03140	COG4565	transcriptional regulatory protein
KM387_03145	COG3493	citrate carrier protein
KM387_03150	COG0281	malic enzyme
KM387_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_03175	COG5002	protein histidine kinase activity
KM387_03180	COG0745	RESPONSE REGULATOR receiver
KM387_03185	COG0456	acetyltransferase
KM387_03185	COG0454	-acetyltransferase
KM387_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM387_03195	COG3383	formate dehydrogenase (NAD+) activity
KM387_03200	COG2427	Protein of unknown function (DUF1641)
KM387_03215	COG0531	amino acid
KM387_03220	COG0640	Transcriptional regulator
KM387_03225	COG2217	Heavy metal translocating P-type atpase
KM387_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM387_03245	COG3227	Zinc metalloprotease (Elastase)
KM387_03265	COG2720	vancomycin resistance protein
KM387_03270	COG1316	TRANSCRIPTIONal
KM387_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_03280	COG0346	lactoylglutathione lyase activity
KM387_03285	COG1253	flavin adenine dinucleotide binding
KM387_03290	COG1027	Aspartate ammonia-lyase
KM387_03295	COG1620	l-lactate permease
KM387_03310	COG3104	oligopeptide transport
KM387_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_03335	COG2226	methyltransferase
KM387_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM387_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_03355	COG4548	von Willebrand factor, type A
KM387_03360	COG0714	Associated with various cellular activities
KM387_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_03385	COG0531	amino acid
KM387_03390	COG2188	Transcriptional regulator
KM387_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_03395	COG1263	PTS System
KM387_03400	COG0366	Alpha amylase catalytic
KM387_03415	COG0697	spore germination
KM387_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_03430	COG1115	amino acid carrier protein
KM387_03435	COG1126	abc transporter atp-binding protein
KM387_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_03445	COG0765	amino acid transport
KM387_03450	COG0765	amino acid transport
KM387_03455	COG0833	amino acid
KM387_03480	COG2378	regulation of single-species biofilm formation
KM387_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM387_03490	COG5002	protein histidine kinase activity
KM387_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM387_03520	COG0747	negative chemotaxis
KM387_03530	COG0601	transmembrane transport
KM387_03535	COG4608	Belongs to the ABC transporter superfamily
KM387_03545	COG2271	Major facilitator Superfamily
KM387_03550	COG1846	Transcriptional regulator
KM387_03560	COG1609	Transcriptional regulator
KM387_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM387_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM387_03585	COG1879	ABC-type sugar transport system periplasmic component
KM387_03610	COG1063	alcohol dehydrogenase
KM387_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM387_03650	COG1968	undecaprenyl-diphosphatase activity
KM387_03655	COG0840	transmembrane signaling receptor activity
KM387_03660	COG1388	LysM domain
KM387_03660	COG3584	3D domain protein
KM387_03665	COG1476	TRANSCRIPTIONal
KM387_03680	COG3104	oligopeptide transport
KM387_03685	COG1114	Component of the transport system for branched-chain amino acids
KM387_03700	COG1113	amino acid transport
KM387_03705	COG2252	PERMEase
KM387_03730	COG0569	domain protein
KM387_03730	COG0475	glutathione-regulated potassium exporter activity
KM387_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM387_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM387_03755	COG0833	amino acid
KM387_03760	COG4990	cell redox homeostasis
KM387_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_03780	COG0697	spore germination
KM387_03785	COG0531	amino acid
KM387_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_03805	COG1918	ferrous iron import across plasma membrane
KM387_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM387_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM387_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM387_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM387_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM387_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM387_03975	COG1116	anion transmembrane transporter activity
KM387_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM387_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_04000	COG2104	thiamine diphosphate biosynthetic process
KM387_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_04015	COG0351	phosphomethylpyrimidine kinase
KM387_04055	COG2205	protein histidine kinase activity
KM387_04060	COG2814	Major facilitator Superfamily
KM387_04065	COG1846	Transcriptional regulator
KM387_04080	COG2252	PERMEase
KM387_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_04090	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM387_04105	COG1621	beta-fructofuranosidase activity
KM387_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_04110	COG1263	PTS System
KM387_04115	COG1609	Transcriptional regulator
KM387_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_04165	COG0778	Nitroreductase
KM387_04170	COG2719	SpoVR family
KM387_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM387_04200	COG1937	Protein conserved in bacteria
KM387_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM387_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM387_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM387_04235	COG0730	response to heat
KM387_04245	COG1316	TRANSCRIPTIONal
KM387_04250	COG0604	alcohol dehydrogenase
KM387_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM387_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM387_04270	COG3711	transcriptional antiterminator
KM387_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_04300	COG3584	3D domain protein
KM387_04300	COG1388	LysM domain
KM387_04305	COG0577	efflux transmembrane transporter activity
KM387_04310	COG1136	(ABC) transporter
KM387_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM387_04335	COG1114	Component of the transport system for branched-chain amino acids
KM387_04340	COG3546	catalase activity
KM387_04375	COG0586	Pfam SNARE associated Golgi protein
KM387_04410	COG0531	amino acid
KM387_04415	COG0475	glutathione-regulated potassium exporter activity
KM387_04425	COG1737	Transcriptional regulator
KM387_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_04435	COG1263	PTS System
KM387_04445	COG2259	Doxx family
KM387_04460	COG0697	spore germination
KM387_04465	COG1522	sequence-specific DNA binding
KM387_04480	COG2076	Multidrug Resistance protein
KM387_04485	COG1309	transcriptional regulator
KM387_04490	COG2814	Major facilitator Superfamily
KM387_04495	COG1733	regulation of RNA biosynthetic process
KM387_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_04510	COG4533	DNA binding
KM387_04515	COG2211	Major facilitator Superfamily
KM387_04525	COG0693	protein deglycase activity
KM387_04530	COG0693	protein deglycase activity
KM387_04530	COG0753	catalase activity
KM387_04540	COG0531	amino acid
KM387_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM387_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM387_04560	COG1132	(ABC) transporter
KM387_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_04575	COG0765	amino acid transport
KM387_04580	COG1126	abc transporter atp-binding protein
KM387_04595	COG0189	ligase activity
KM387_04625	COG0028	Belongs to the TPP enzyme family
KM387_04630	COG3527	Alpha-acetolactate decarboxylase
KM387_04645	COG0561	phosphatase activity
KM387_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM387_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM387_04695	COG0653	protein targeting
KM387_04700	COG2244	polysaccharide biosynthetic process
KM387_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_04715	COG4196	transglutaminase domain protein
KM387_04730	COG1696	Membrane protein involved in D-alanine export
KM387_04745	COG1024	Enoyl-CoA hydratase
KM387_04765	COG1363	Peptidase, m42
KM387_04785	COG3938	Belongs to the proline racemase family
KM387_04825	COG0601	transmembrane transport
KM387_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_04840	COG4608	Belongs to the ABC transporter superfamily
KM387_04845	COG0322	excinuclease ABC activity
KM387_04875	COG0477	Major facilitator Superfamily
KM387_04880	COG3290	protein histidine kinase activity
KM387_04885	COG4565	transcriptional regulatory protein
KM387_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM387_04920	COG0789	Transcriptional regulator
KM387_04920	COG4978	Transcriptional regulator
KM387_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM387_04975	COG0477	Major facilitator Superfamily
KM387_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_05020	COG3320	Male sterility
KM387_05025	COG1309	transcriptional regulator
KM387_05045	COG1183	phosphatidylcholine synthase activity
KM387_05065	COG2376	Dihydroxyacetone kinase
KM387_05075	COG2376	Dihydroxyacetone kinase
KM387_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_05085	COG1959	2 iron, 2 sulfur cluster binding
KM387_05115	COG2770	Histidine kinase
KM387_05115	COG3437	response regulator, receiver
KM387_05165	COG3237	CsbD-like
KM387_05190	COG1191	sigma factor activity
KM387_05200	COG2208	phosphoserine phosphatase activity
KM387_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM387_05210	COG0784	Response regulator, receiver
KM387_05210	COG2205	protein histidine kinase activity
KM387_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_05210	COG2198	Histidine kinase
KM387_05265	COG0420	3'-5' exonuclease activity
KM387_05270	COG4717	serine-type aminopeptidase activity
KM387_05290	COG1309	transcriptional regulator
KM387_05295	COG2814	Major facilitator Superfamily
KM387_05300	COG0346	lactoylglutathione lyase activity
KM387_05305	COG0346	lactoylglutathione lyase activity
KM387_05310	COG0457	Tetratricopeptide repeat
KM387_05315	COG2267	carboxylic ester hydrolase activity
KM387_05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM387_05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM387_05390	COG0477	Major facilitator Superfamily
KM387_05395	COG0477	Major facilitator Superfamily
KM387_05405	COG3973	AAA domain
KM387_05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_05430	COG4980	gas vesicle protein
KM387_05435	COG0537	adenosine 5'-monophosphoramidase activity
KM387_05440	COG1131	(ABC) transporter
KM387_05445	COG4473	ABC transporter
KM387_05460	COG1309	transcriptional regulator
KM387_05470	COG3402	PFAM membrane-flanked domain
KM387_05475	COG3428	Bacterial PH domain
KM387_05515	COG3402	PFAM membrane-flanked domain
KM387_05525	COG2329	Antibiotic biosynthesis monooxygenase
KM387_05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM387_05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM387_05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM387_05580	COG1309	transcriptional regulator
KM387_05585	COG1511	domain protein
KM387_05610	COG1609	Transcriptional regulator
KM387_05620	COG1234	tRNA 3'-trailer cleavage
KM387_05625	COG0095	Lipoate-protein ligase
KM387_05635	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_05665	COG3209	COG3209 Rhs family protein
KM387_05700	COG1408	metallophosphoesterase
KM387_05705	COG1078	dGTPase activity
KM387_05715	COG1595	DNA-templated transcription, initiation
KM387_05720	COG2207	Transcriptional regulator
KM387_05720	COG3708	Transcriptional regulator
KM387_05735	COG2205	protein histidine kinase activity
KM387_05740	COG0745	RESPONSE REGULATOR receiver
KM387_05765	COG0501	Belongs to the peptidase M48B family
KM387_05770	COG0840	transmembrane signaling receptor activity
KM387_05775	COG0697	spore germination
KM387_05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM387_05800	COG2224	Isocitrate lyase
KM387_05825	COG4903	ComK protein
KM387_05830	COG0398	Pfam SNARE associated Golgi protein
KM387_05840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM387_05845	COG1074	ATP-dependent DNA helicase activity
KM387_05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM387_05915	COG0367	asparagine synthase
KM387_05920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM387_05925	COG0753	catalase activity
KM387_05930	COG0004	ammonium transporteR
KM387_05950	COG2996	Protein conserved in bacteria
KM387_05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_05985	COG0561	phosphatase activity
KM387_05995	COG0542	response to heat
KM387_06005	COG2267	carboxylic ester hydrolase activity
KM387_06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM387_06030	COG5504	Zn-dependent protease
KM387_06040	COG0180	Tryptophanyl-tRNA synthetase
KM387_06050	COG4166	transmembrane transport
KM387_06055	COG0601	transmembrane transport
KM387_06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_06065	COG0444	Belongs to the ABC transporter superfamily
KM387_06070	COG4608	Belongs to the ABC transporter superfamily
KM387_06075	COG0534	Mate efflux family protein
KM387_06080	COG4166	transmembrane transport
KM387_06095	COG0861	Integral membrane protein TerC family
KM387_06100	COG4862	establishment of competence for transformation
KM387_06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_06125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM387_06130	COG2346	COG2346, Truncated hemoglobins
KM387_06135	COG4116	CYTH
KM387_06145	COG2357	RelA SpoT domain protein
KM387_06155	COG0564	pseudouridine synthase activity
KM387_06170	COG0772	Belongs to the SEDS family
KM387_06175	COG0463	Glycosyl transferase, family 2
KM387_06175	COG1216	Glycosyl transferase, family 2
KM387_06215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM387_06230	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM387_06275	COG2153	protein acetylation
KM387_06285	COG2382	esterase
KM387_06300	COG5492	domain, Protein
KM387_06305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_06350	COG1620	l-lactate permease
KM387_06355	COG5634	Uncharacterized conserved protein (DUF2278)
KM387_06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_06420	COG1476	TRANSCRIPTIONal
KM387_06480	COG2226	methyltransferase
KM387_06490	COG1686	Belongs to the peptidase S11 family
KM387_06495	COG0681	Belongs to the peptidase S26 family
KM387_06530	COG1012	belongs to the aldehyde dehydrogenase family
KM387_06535	COG3842	ATPase activity
KM387_06540	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM387_06545	COG1177	transmembrane transport
KM387_06550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM387_06560	COG2409	Drug exporters of the RND superfamily
KM387_06570	COG0564	pseudouridine synthase activity
KM387_06580	COG2340	Cysteine-rich secretory protein family
KM387_06585	COG0247	lactate metabolic process
KM387_06590	COG0277	FAD linked oxidase domain protein
KM387_06595	COG3835	regulator
KM387_06605	COG0745	RESPONSE REGULATOR receiver
KM387_06610	COG5002	protein histidine kinase activity
KM387_06615	COG2186	Transcriptional regulator
KM387_06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM387_06645	COG2116	formate transmembrane transporter activity
KM387_06650	COG0861	Integral membrane protein TerC family
KM387_06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_06665	COG2030	dehydratase
KM387_06685	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_06690	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM387_06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_06715	COG1840	ABC-type Fe3 transport system, periplasmic component
KM387_06745	COG1349	DNA-binding transcription factor activity
KM387_06765	COG2861	carbohydrate metabolic process
KM387_06775	COG3852	Histidine kinase
KM387_06780	COG1846	Transcriptional regulator
KM387_06790	COG2318	DinB family
KM387_06805	COG0720	synthase
KM387_06820	COG4873	Protein conserved in bacteria
KM387_06850	COG1780	Probably involved in ribonucleotide reductase function
KM387_06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM387_06875	COG1725	Transcriptional regulator
KM387_06880	COG1131	(ABC) transporter
KM387_06890	COG1131	(ABC) transporter
KM387_06895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_06910	COG1522	sequence-specific DNA binding
KM387_06920	COG1335	isochorismatase
KM387_06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_06935	COG2070	2-Nitropropane dioxygenase
KM387_06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM387_06950	COG1696	Membrane protein involved in D-alanine export
KM387_06975	COG0716	FMN binding
KM387_06990	COG3173	Aminoglycoside phosphotransferase
KM387_07010	COG0534	Mate efflux family protein
KM387_07015	COG1968	undecaprenyl-diphosphatase activity
KM387_07030	COG1846	Transcriptional regulator
KM387_07040	COG1301	dicarboxylic acid transport
KM387_07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_07050	COG4709	membrane
KM387_07055	COG3874	Sporulation protein YtfJ
KM387_07080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_07085	COG0028	Belongs to the TPP enzyme family
KM387_07090	COG0440	acetolactate synthase activity
KM387_07095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM387_07105	COG0473	3-isopropylmalate dehydrogenase activity
KM387_07130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM387_07165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM387_07180	COG1183	phosphatidylcholine synthase activity
KM387_07185	COG1368	sulfuric ester hydrolase activity
KM387_07195	COG0019	diaminopimelate decarboxylase activity
KM387_07215	COG0529	Catalyzes the synthesis of activated sulfate
KM387_07220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM387_07240	COG1648	precorrin-2 dehydrogenase activity
KM387_07245	COG0733	neurotransmitter:sodium symporter activity
KM387_07265	COG1757	Na H antiporter
KM387_07280	COG4758	membrane
KM387_07285	COG4585	Histidine kinase
KM387_07290	COG2197	response regulator
KM387_07300	COG1114	Component of the transport system for branched-chain amino acids
KM387_07310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM387_07335	COG1017	nitric oxide dioxygenase activity
KM387_07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM387_07350	COG0730	response to heat
KM387_07355	COG0306	phosphate transporter
KM387_07360	COG1392	Phosphate transport regulator
KM387_07365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_07380	COG3852	Histidine kinase
KM387_07385	COG1801	Protein of unknown function DUF72
KM387_07395	COG0582	viral genome integration into host DNA
KM387_07400	COG5002	protein histidine kinase activity
KM387_07420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM387_07420	COG0392	lysyltransferase activity
KM387_07435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_07440	COG1686	Belongs to the peptidase S11 family
KM387_07445	COG2715	membrane protein required for spore maturation
KM387_07450	COG0700	Nucleoside recognition
KM387_07455	COG1187	pseudouridine synthase activity
KM387_07465	COG1333	cytochrome c biogenesis protein
KM387_07470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM387_07475	COG0745	RESPONSE REGULATOR receiver
KM387_07480	COG5002	protein histidine kinase activity
KM387_07485	COG2096	Adenosyltransferase
KM387_07500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM387_07505	COG1141	Ferredoxin
KM387_07515	COG0514	ATP-dependent DNA helicase (RecQ)
KM387_07520	COG1266	CAAX protease self-immunity
KM387_07530	COG1408	metallophosphoesterase
KM387_07540	COG4862	establishment of competence for transformation
KM387_07545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM387_07565	COG0492	ferredoxin-NADP+ reductase activity
KM387_07640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_07655	COG0142	geranyltranstransferase activity
KM387_07665	COG0142	geranyltranstransferase activity
KM387_07685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM387_07690	COG0457	Tetratricopeptide repeat
KM387_07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM387_07720	COG4347	Protein of unknown function (DUF1405)
KM387_07735	COG2738	Putative neutral zinc metallopeptidase
KM387_07745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_07750	COG1694	Mazg nucleotide pyrophosphohydrolase
KM387_07765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_07770	COG0438	transferase activity, transferring glycosyl groups
KM387_07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM387_07805	COG1199	ATP-dependent helicase activity
KM387_07825	COG3935	DnaD domain protein
KM387_07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM387_07840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_07840	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM387_07900	COG0116	Belongs to the methyltransferase superfamily
KM387_07910	COG1199	ATP-dependent helicase activity
KM387_07915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM387_07925	COG3173	Aminoglycoside phosphotransferase
KM387_07930	COG0024	Methionine aminopeptidase
KM387_07940	COG2233	PERMEase
KM387_07945	COG2311	Membrane
KM387_07950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_07960	COG0456	acetyltransferase
KM387_07995	COG0754	glutathionylspermidine amidase activity
KM387_08010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_08030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM387_08045	COG1215	transferase activity, transferring glycosyl groups
KM387_08050	COG0438	transferase activity, transferring glycosyl groups
KM387_08070	COG1396	sequence-specific DNA binding
KM387_08070	COG3800	Transcriptional regulator
KM387_08135	COG0662	Cupin 2, conserved barrel domain protein
KM387_08215	COG1802	Transcriptional regulator
KM387_08215	COG4626	Terminase
KM387_08280	COG4824	toxin secretion phage lysis holin
KM387_08345	COG0454	-acetyltransferase
KM387_08365	COG0328	RNA-DNA hybrid ribonuclease activity
KM387_08405	COG1280	lysine exporter protein (LysE YggA)
KM387_08420	COG3162	membrane
KM387_08425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_08430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_08440	COG0475	glutathione-regulated potassium exporter activity
KM387_08445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_08450	COG4978	Transcriptional regulator
KM387_08450	COG0789	Transcriptional regulator
KM387_08460	COG2323	membrane
KM387_08465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM387_08520	COG1923	regulation of RNA biosynthetic process
KM387_08530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM387_08535	COG1360	Flagellar Motor Protein
KM387_08540	COG2201	protein-glutamate methylesterase activity
KM387_08545	COG0643	Histidine kinase
KM387_08545	COG2198	Histidine kinase
KM387_08550	COG1776	CheC inhibitor of MCP methylation
KM387_08550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_08565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM387_08585	COG1256	bacterial-type flagellum assembly
KM387_08590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM387_08610	COG1815	bacterial-type flagellum-dependent cell motility
KM387_08615	COG1558	bacterial-type flagellum-dependent cell motility
KM387_08625	COG1766	The M ring may be actively involved in energy transduction
KM387_08630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_08640	COG1157	protein secretion by the type III secretion system
KM387_08675	COG0784	Response regulator, receiver
KM387_08675	COG0835	chemotaxis
KM387_08685	COG0463	Glycosyl transferase, family 2
KM387_08710	COG0457	Tetratricopeptide repeat
KM387_08710	COG0463	Glycosyl transferase, family 2
KM387_08725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM387_08740	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_08745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_08745	COG1776	CheC inhibitor of MCP methylation
KM387_08755	COG1338	Plays a role in the flagellum-specific transport system
KM387_08760	COG1987	bacterial-type flagellum assembly
KM387_08770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM387_08775	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM387_08780	COG1419	protein localization to endoplasmic reticulum
KM387_08785	COG4786	Flagellar basal body rod
KM387_08790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_08815	COG1309	transcriptional regulator
KM387_08835	COG2329	Antibiotic biosynthesis monooxygenase
KM387_08860	COG0583	DNA-binding transcription factor activity
KM387_08865	COG3842	ATPase activity
KM387_08870	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM387_08880	COG1234	tRNA 3'-trailer cleavage
KM387_08905	COG1686	Belongs to the peptidase S11 family
KM387_08915	COG0406	alpha-ribazole phosphatase activity
KM387_08935	COG1846	Transcriptional regulator
KM387_08945	COG0367	asparagine synthase
KM387_08975	COG1802	Transcriptional regulator
KM387_08980	COG0697	spore germination
KM387_08985	COG0523	cobalamin synthesis protein
KM387_08990	COG0701	Predicted permease
KM387_09000	COG0438	transferase activity, transferring glycosyl groups
KM387_09000	COG1216	Glycosyl transferase, family 2
KM387_09005	COG1757	Na H antiporter
KM387_09010	COG0114	fumarate hydratase activity
KM387_09030	COG0534	Mate efflux family protein
KM387_09035	COG3340	Belongs to the peptidase S51 family
KM387_09055	COG0785	Cytochrome C biogenesis protein
KM387_09085	COG2733	membrane
KM387_09115	COG1131	(ABC) transporter
KM387_09130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_09135	COG0528	UMP kinase activity
KM387_09145	COG1027	Aspartate ammonia-lyase
KM387_09150	COG0281	malic enzyme
KM387_09155	COG4191	Histidine kinase
KM387_09160	COG0784	Response regulator, receiver
KM387_09165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_09220	COG1051	belongs to the nudix hydrolase family
KM387_09225	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_09235	COG2814	Major facilitator Superfamily
KM387_09250	COG1966	Carbon starvation protein
KM387_09260	COG0477	Major facilitator Superfamily
KM387_09265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_09275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM387_09280	COG4166	transmembrane transport
KM387_09285	COG2223	nitrite transmembrane transporter activity
KM387_09290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_09305	COG2244	polysaccharide biosynthetic process
KM387_09310	COG0733	neurotransmitter:sodium symporter activity
KM387_09320	COG5566	PFAM Mor transcription activator
KM387_09325	COG2323	membrane
KM387_09340	COG2084	Dehydrogenase
KM387_09355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_09365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_09370	COG0028	Belongs to the TPP enzyme family
KM387_09375	COG0440	acetolactate synthase activity
KM387_09380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM387_09390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM387_09415	COG2814	Major facilitator Superfamily
KM387_09430	COG3279	Response regulator of the LytR AlgR family
KM387_09435	COG0427	acetyl-CoA hydrolase
KM387_09455	COG1073	alpha beta
KM387_09460	COG4166	transmembrane transport
KM387_09485	COG0535	radical SAM domain protein
KM387_09490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_09510	COG1914	H( )-stimulated, divalent metal cation uptake system
KM387_09525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM387_09555	COG2390	Transcriptional regulator
KM387_09565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_09570	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM387_09605	COG0006	proline dipeptidase activity
KM387_09610	COG2132	Multicopper oxidase
KM387_09625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_09640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_09645	COG1114	Component of the transport system for branched-chain amino acids
KM387_09655	COG2372	response to copper ion
KM387_09655	COG1276	copper resistance
KM387_09660	COG4549	nuclear export factor GLE1
KM387_09670	COG0697	spore germination
KM387_09675	COG0583	DNA-binding transcription factor activity
KM387_09680	COG1959	2 iron, 2 sulfur cluster binding
KM387_09685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM387_09700	COG0628	permease
KM387_09710	COG1231	oxidoreductase activity
KM387_09715	COG0523	cobalamin synthesis protein
KM387_09730	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_09735	COG2030	dehydratase
KM387_09740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_09750	COG0411	ABC transporter
KM387_09770	COG0583	DNA-binding transcription factor activity
KM387_09780	COG1942	4-Oxalocrotonate Tautomerase
KM387_09790	COG1846	Transcriptional regulator
KM387_09800	COG1271	oxidase subunit
KM387_09805	COG1294	oxidase, subunit
KM387_09810	COG4988	ABC transporter
KM387_09815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM387_09835	COG1686	Belongs to the peptidase S11 family
KM387_09850	COG0791	NLP P60 protein
KM387_09850	COG1388	LysM domain
KM387_09860	COG1132	(ABC) transporter
KM387_09865	COG0745	RESPONSE REGULATOR receiver
KM387_09870	COG5002	protein histidine kinase activity
KM387_09880	COG0300	oxidoreductase activity
KM387_09915	COG0460	homoserine dehydrogenase
KM387_09940	COG1316	TRANSCRIPTIONal
KM387_09950	COG0745	RESPONSE REGULATOR receiver
KM387_09955	COG5002	protein histidine kinase activity
KM387_09970	COG1285	pathogenesis
KM387_09975	COG1247	-acetyltransferase
KM387_09995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_10005	COG1082	Xylose isomerase domain protein TIM barrel
KM387_10015	COG2814	Major facilitator Superfamily
KM387_10020	COG1279	arginine transmembrane transporter activity
KM387_10030	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM387_10065	COG0577	efflux transmembrane transporter activity
KM387_10070	COG2002	toxin-antitoxin pair type II binding
KM387_10075	COG1404	Belongs to the peptidase S8 family
KM387_10080	COG0640	Transcriptional regulator
KM387_10085	COG0667	Aldo Keto reductase
KM387_10090	COG2814	Major facilitator Superfamily
KM387_10115	COG0840	transmembrane signaling receptor activity
KM387_10130	COG3949	Membrane
KM387_10135	COG0783	Belongs to the Dps family
KM387_10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_10160	COG1231	oxidoreductase activity
KM387_10170	COG4989	oxidoreductase activity
KM387_10175	COG0523	cobalamin synthesis protein
KM387_10180	COG0456	acetyltransferase
KM387_10235	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM387_10235	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM387_10245	COG0702	epimerase
KM387_10255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM387_10265	COG4166	transmembrane transport
KM387_10280	COG0406	alpha-ribazole phosphatase activity
KM387_10290	COG5337	Spore coat protein CotH
KM387_10295	COG1051	belongs to the nudix hydrolase family
KM387_10300	COG0586	Pfam SNARE associated Golgi protein
KM387_10305	COG2244	polysaccharide biosynthetic process
KM387_10315	COG0701	Predicted permease
KM387_10320	COG3689	TIGRFAM TIGR03943 family protein
KM387_10325	COG1607	acyl-coa hydrolase
KM387_10335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_10350	COG0702	epimerase
KM387_10355	COG2839	Protein conserved in bacteria
KM387_10360	COG1253	flavin adenine dinucleotide binding
KM387_10375	COG1114	Component of the transport system for branched-chain amino acids
KM387_10380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_10400	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_10410	COG1876	peptidase activity
KM387_10420	COG0154	amidase activity
KM387_10425	COG2211	Major facilitator Superfamily
KM387_10445	COG0561	phosphatase activity
KM387_10455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM387_10460	COG4106	trans-aconitate 2-methyltransferase activity
KM387_10475	COG1819	glycosyl
KM387_10480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_10485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_10510	COG0456	acetyltransferase
KM387_10560	COG3874	Sporulation protein YtfJ
KM387_10585	COG2226	methyltransferase
KM387_10610	COG0346	lactoylglutathione lyase activity
KM387_10620	COG0604	alcohol dehydrogenase
KM387_10625	COG1595	DNA-templated transcription, initiation
KM387_10650	COG0386	Belongs to the glutathione peroxidase family
KM387_10655	COG1305	Transglutaminase-like
KM387_10660	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM387_10665	COG0714	Associated with various cellular activities
KM387_10680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM387_10685	COG1140	nitrate reductase beta subunit
KM387_10690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM387_10695	COG2181	nitrate reductase activity
KM387_10705	COG1131	(ABC) transporter
KM387_10715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM387_10720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM387_10725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_10730	COG0303	'Molybdopterin
KM387_10735	COG0314	molybdopterin synthase activity
KM387_10745	COG2223	nitrite transmembrane transporter activity
KM387_10760	COG1648	precorrin-2 dehydrogenase activity
KM387_10770	COG1587	Uroporphyrinogen-III synthase
KM387_10770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM387_10775	COG2146	nitrite reductase [NAD(P)H] activity
KM387_10780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM387_10785	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM387_10820	COG2359	stage V sporulation protein S
KM387_10835	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_10850	COG1418	mRNA catabolic process
KM387_10855	COG0488	(ABC) transporter
KM387_10870	COG0629	single-stranded DNA binding
KM387_10885	COG1413	lyase activity
KM387_10900	COG2521	methyltransferase
KM387_10900	COG2136	Putative SAM-dependent methyltransferase
KM387_10905	COG0018	arginyl-trna synthetase
KM387_10930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM387_10950	COG0017	Asparaginyl-tRNA synthetase
KM387_10970	COG1674	ftsk spoiiie
KM387_11045	COG1929	Belongs to the glycerate kinase type-1 family
KM387_11050	COG0471	metal ion transport
KM387_11055	COG0745	RESPONSE REGULATOR receiver
KM387_11060	COG3850	Histidine kinase
KM387_11060	COG5002	protein histidine kinase activity
KM387_11075	COG0733	neurotransmitter:sodium symporter activity
KM387_11100	COG2610	gluconate transmembrane transporter activity
KM387_11105	COG1454	alcohol dehydrogenase
KM387_11110	COG1794	racemase activity, acting on amino acids and derivatives
KM387_11120	COG0456	acetyltransferase
KM387_11135	COG1131	(ABC) transporter
KM387_11140	COG4473	ABC transporter
KM387_11150	COG0546	phosphoglycolate phosphatase activity
KM387_11170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_11185	COG0768	penicillin binding
KM387_11190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_11195	COG0204	Acyl-transferase
KM387_11200	COG1272	protein, Hemolysin III
KM387_11210	COG0805	protein transport
KM387_11220	COG1307	EDD domain protein, DegV family
KM387_11225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM387_11230	COG1999	signal sequence binding
KM387_11235	COG0071	Belongs to the small heat shock protein (HSP20) family
KM387_11240	COG0367	asparagine synthase
KM387_11255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_11260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_11285	COG1051	belongs to the nudix hydrolase family
KM387_11290	COG0071	Belongs to the small heat shock protein (HSP20) family
KM387_11295	COG0668	transmembrane transport
KM387_11300	COG2203	Gaf domain
KM387_11300	COG4585	Histidine kinase
KM387_11305	COG2197	response regulator
KM387_11315	COG1064	alcohol dehydrogenase
KM387_11340	COG1070	Carbohydrate kinase
KM387_11345	COG1070	Carbohydrate kinase
KM387_11375	COG1125	glycine betaine transport
KM387_11375	COG0517	IMP dehydrogenase activity
KM387_11380	COG1174	glycine betaine transport
KM387_11415	COG1253	flavin adenine dinucleotide binding
KM387_11420	COG1012	belongs to the aldehyde dehydrogenase family
KM387_11425	COG5506	Protein of unknown function (DUF1694)
KM387_11440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_11445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM387_11450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM387_11455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_11460	COG0456	acetyltransferase
KM387_11465	COG3829	transcription factor binding
KM387_11470	COG1509	lysine 2,3-aminomutase activity
KM387_11510	COG4326	sporulation control protein
KM387_11515	COG0671	phosphoesterase, PA-phosphatase related
KM387_11520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM387_11525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_11555	COG1715	Restriction endonuclease
KM387_11555	COG1787	Restriction endonuclease
KM387_11645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_11685	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM387_11685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_11690	COG2814	Major facilitator Superfamily
KM387_11695	COG4841	protein insertion into membrane
KM387_11700	COG0372	Belongs to the citrate synthase family
KM387_11705	COG2079	MmgE PrpD family protein
KM387_11710	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM387_11715	COG1960	acyl-CoA dehydrogenase activity
KM387_11720	COG2084	Dehydrogenase
KM387_11730	COG1280	lysine exporter protein (LysE YggA)
KM387_11735	COG1024	Enoyl-CoA hydratase
KM387_11750	COG0420	3'-5' exonuclease activity
KM387_11755	COG0419	ATPase involved in DNA repair
KM387_11775	COG2223	nitrite transmembrane transporter activity
KM387_11780	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_11785	COG1169	isochorismate synthase
KM387_11790	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM387_11795	COG1535	isochorismatase
KM387_11795	COG3433	isochorismatase activity
KM387_11800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM387_11805	COG3251	PFAM MbtH domain protein
KM387_11810	COG2814	Major facilitator Superfamily
KM387_11825	COG0776	regulation of translation
KM387_11835	COG2318	DinB family
KM387_11845	COG1115	amino acid carrier protein
KM387_11860	COG2329	Antibiotic biosynthesis monooxygenase
KM387_11865	COG1187	pseudouridine synthase activity
KM387_11870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM387_11875	COG1136	(ABC) transporter
KM387_11885	COG0596	Alpha beta hydrolase
KM387_11890	COG2814	Major facilitator Superfamily
KM387_11910	COG2226	methyltransferase
KM387_11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_11990	COG1247	-acetyltransferase
KM387_12020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM387_12030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_12040	COG1278	Cold shock
KM387_12055	COG0010	Belongs to the arginase family
KM387_12060	COG0561	phosphatase activity
KM387_12105	COG0583	DNA-binding transcription factor activity
KM387_12110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM387_12125	COG0583	DNA-binding transcription factor activity
KM387_12130	COG2258	MOSC domain
KM387_12145	COG1132	(ABC) transporter
KM387_12150	COG1132	(ABC) transporter
KM387_12170	COG1396	sequence-specific DNA binding
KM387_12195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM387_12200	COG1595	DNA-templated transcription, initiation
KM387_12225	COG1649	PFAM Uncharacterised BCR, COG1649
KM387_12250	COG2971	BadF BadG BcrA BcrD
KM387_12255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_12260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM387_12280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_12310	COG1309	transcriptional regulator
KM387_12325	COG1136	(ABC) transporter
KM387_12325	COG0577	efflux transmembrane transporter activity
KM387_12330	COG0500	methyltransferase
KM387_12330	COG3615	Tellurite resistance protein tehB
KM387_12340	COG2226	methyltransferase
KM387_12345	COG3961	Belongs to the TPP enzyme family
KM387_12350	COG1846	Transcriptional regulator
KM387_12390	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM387_12405	COG1595	DNA-templated transcription, initiation
KM387_12415	COG0768	penicillin binding
KM387_12420	COG0768	penicillin binding
KM387_12425	COG2367	Beta-lactamase
KM387_12435	COG1609	Transcriptional regulator
KM387_12440	COG2814	Major facilitator Superfamily
KM387_12445	COG0673	inositol 2-dehydrogenase activity
KM387_12470	COG0191	fructose-bisphosphate aldolase activity
KM387_12475	COG3718	enzyme involved in inositol metabolism
KM387_12490	COG0737	Belongs to the 5'-nucleotidase family
KM387_12500	COG0457	Tetratricopeptide repeat
KM387_12505	COG1476	TRANSCRIPTIONal
KM387_12520	COG1876	peptidase activity
KM387_12540	COG1309	transcriptional regulator
KM387_12545	COG0488	(ABC) transporter
KM387_12560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_12575	COG1252	NADH dehydrogenase
KM387_12580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_12595	COG1131	(ABC) transporter
KM387_12605	COG1309	transcriptional regulator
KM387_12620	COG1960	acyl-CoA dehydrogenase activity
KM387_12625	COG0439	Biotin carboxylase
KM387_12630	COG0511	ligase activity, forming carbon-carbon bonds
KM387_12635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM387_12640	COG1024	Enoyl-CoA hydratase
KM387_12645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM387_12650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_12660	COG1247	-acetyltransferase
KM387_12665	COG0572	uridine kinase
KM387_12675	COG2318	DinB family
KM387_12680	COG1686	Belongs to the peptidase S11 family
KM387_12705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM387_12745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_12745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_12770	COG2814	Major facilitator Superfamily
KM387_12790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_12810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_12825	COG1063	alcohol dehydrogenase
KM387_12840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM387_12855	COG3773	Cell wall hydrolase
KM387_12865	COG0745	RESPONSE REGULATOR receiver
KM387_12880	COG0488	(ABC) transporter
KM387_12895	COG1136	(ABC) transporter
KM387_12900	COG0577	efflux transmembrane transporter activity
KM387_12920	COG0460	homoserine dehydrogenase
KM387_12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_12935	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM387_13000	COG2124	cytochrome p450
KM387_13035	COG0561	phosphatase activity
KM387_13045	COG5002	protein histidine kinase activity
KM387_13050	COG0768	penicillin binding
KM387_13055	COG1819	glycosyl
KM387_13060	COG1794	racemase activity, acting on amino acids and derivatives
KM387_13070	COG1122	ATPase activity
KM387_13085	COG2205	protein histidine kinase activity
KM387_13095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_13100	COG0604	alcohol dehydrogenase
KM387_13105	COG0768	penicillin binding
KM387_13150	COG0693	protein deglycase activity
KM387_13180	COG2814	Major facilitator Superfamily
KM387_13195	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_13215	COG0697	spore germination
KM387_13240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_13250	COG2223	nitrite transmembrane transporter activity
KM387_13265	COG2816	NAD+ diphosphatase activity
KM387_13270	COG0592	DNA-directed DNA polymerase activity
KM387_13275	COG1051	belongs to the nudix hydrolase family
KM387_13310	COG3878	Protein conserved in bacteria
KM387_13355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM387_13370	COG0322	excinuclease ABC activity
KM387_13410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_13435	COG1011	Hydrolase
KM387_13450	COG0657	acetylesterase activity
KM387_13455	COG0076	glutamate decarboxylase activity
KM387_13470	COG1523	belongs to the glycosyl hydrolase 13 family
KM387_13475	COG3227	Zinc metalloprotease (Elastase)
KM387_13495	COG0201	protein transport
KM387_13505	COG0697	spore germination
KM387_13510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_13540	COG4129	membrane
KM387_13545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_13560	COG2959	enzyme of heme biosynthesis
KM387_13580	COG3483	tryptophan 2,3-dioxygenase activity
KM387_13585	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM387_13590	COG3844	kynureninase activity
KM387_13595	COG1309	transcriptional regulator
KM387_13625	COG3284	Transcriptional regulator
KM387_13645	COG1349	DNA-binding transcription factor activity
KM387_13665	COG1959	2 iron, 2 sulfur cluster binding
KM387_13680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM387_13685	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_13690	COG0022	dehydrogenase e1 component
KM387_13695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_13705	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_13710	COG0456	acetyltransferase
KM387_13710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_13740	COG4176	ABC-type proline glycine betaine transport system permease component
KM387_13745	COG0517	IMP dehydrogenase activity
KM387_13745	COG4175	Glycine betaine
KM387_13770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM387_13775	COG2153	protein acetylation
KM387_13780	COG3397	chitin binding
KM387_13795	COG2205	protein histidine kinase activity
KM387_13820	COG0658	competence protein
KM387_13820	COG2333	competence protein COMEC
KM387_13870	COG3973	AAA domain
KM387_13885	COG2105	PFAM AIG2 family protein
KM387_13890	COG0514	ATP-dependent DNA helicase (RecQ)
KM387_13910	COG4637	Psort location Cytoplasmic, score
KM387_13935	COG3397	chitin binding
KM387_13950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM387_13955	COG1115	amino acid carrier protein
KM387_13960	COG1012	belongs to the aldehyde dehydrogenase family
KM387_13965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM387_13975	COG3938	Belongs to the proline racemase family
KM387_13980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_14020	COG0586	Pfam SNARE associated Golgi protein
KM387_14035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM387_14040	COG0519	Catalyzes the synthesis of GMP from XMP
KM387_14045	COG4166	transmembrane transport
KM387_14055	COG4948	Mandelate Racemase Muconate Lactonizing
KM387_14100	COG2936	dipeptidyl-peptidase activity
KM387_14105	COG5002	protein histidine kinase activity
KM387_14110	COG0745	RESPONSE REGULATOR receiver
KM387_14145	COG1164	Oligoendopeptidase f
KM387_14155	COG1307	EDD domain protein, DegV family
KM387_14175	COG2814	Major facilitator Superfamily
KM387_14185	COG1664	Polymer-forming cytoskeletal
KM387_14190	COG0789	Transcriptional regulator
KM387_14195	COG4533	DNA binding
KM387_14200	COG0477	Major facilitator Superfamily
KM387_14200	COG2814	Major facilitator Superfamily
KM387_14220	COG2261	transglycosylase associated protein
KM387_14235	COG2226	methyltransferase
KM387_14270	COG0436	Aminotransferase
KM387_14275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM387_14280	COG5146	pantothenate kinase activity
KM387_14300	COG1131	(ABC) transporter
KM387_14345	COG0628	permease
KM387_14355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_14360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_14365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_14370	COG1116	anion transmembrane transporter activity
KM387_14390	COG2816	NAD+ diphosphatase activity
KM387_14410	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM387_14435	COG0697	spore germination
KM387_14440	COG2318	DinB family
KM387_14460	COG4912	Dna alkylation repair
KM387_14480	COG0861	Integral membrane protein TerC family
KM387_14485	COG1368	sulfuric ester hydrolase activity
KM387_14490	COG0488	(ABC) transporter
KM387_14500	COG1033	growth of symbiont in host cell
KM387_14500	COG2409	Drug exporters of the RND superfamily
KM387_14505	COG1309	transcriptional regulator
KM387_14520	COG0287	Prephenate dehydrogenase
KM387_14525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM387_14530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM387_14535	COG1605	Chorismate mutase
KM387_14535	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM387_14570	COG1388	LysM domain
KM387_14570	COG3584	3D domain protein
KM387_14580	COG1595	DNA-templated transcription, initiation
KM387_14605	COG1879	ABC-type sugar transport system periplasmic component
KM387_14615	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM387_14625	COG2390	Transcriptional regulator
KM387_14630	COG1070	Carbohydrate kinase
KM387_14660	COG2329	Antibiotic biosynthesis monooxygenase
KM387_14680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_14690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM387_14695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_14700	COG4187	Peptidase family M20/M25/M40
KM387_14705	COG1414	Transcriptional regulator
KM387_14710	COG0833	amino acid
KM387_14715	COG1690	Belongs to the RtcB family
KM387_14720	COG3239	Fatty acid desaturase
KM387_14725	COG1785	Belongs to the alkaline phosphatase family
KM387_14735	COG3655	Transcriptional regulator
KM387_14750	COG4377	Putative membrane peptidase family (DUF2324)
KM387_14760	COG3279	Response regulator of the LytR AlgR family
KM387_14770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_14775	COG0346	lactoylglutathione lyase activity
KM387_14795	COG0714	Associated with various cellular activities
KM387_14820	COG0463	Glycosyl transferase, family 2
KM387_14840	COG0463	Glycosyl transferase, family 2
KM387_14850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM387_14855	COG0753	catalase activity
KM387_14865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM387_14890	COG0714	Associated with various cellular activities
KM387_14900	COG0778	Nitroreductase
KM387_14905	COG1846	Transcriptional regulator
KM387_14940	COG1725	Transcriptional regulator
KM387_14950	COG0577	efflux transmembrane transporter activity
KM387_14950	COG1136	(ABC) transporter
KM387_14975	COG2207	Transcriptional regulator
KM387_14980	COG0456	acetyltransferase
KM387_15000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_15020	COG0642	Histidine kinase
KM387_15025	COG0745	RESPONSE REGULATOR receiver
KM387_15030	COG0596	Alpha beta hydrolase
KM387_15060	COG0730	response to heat
KM387_15070	COG0833	amino acid
KM387_15080	COG4335	DNA alkylation repair
KM387_15130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM387_15160	COG1984	allophanate hydrolase subunit 2
KM387_15165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM387_15170	COG1414	Transcriptional regulator
KM387_15185	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_15190	COG0640	Transcriptional regulator
KM387_15200	COG1960	acyl-CoA dehydrogenase activity
KM387_15215	COG3314	Sporulation integral membrane protein YlbJ
KM387_15230	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM387_15245	COG0574	Belongs to the PEP-utilizing enzyme family
KM387_15245	COG3848	Pyruvate phosphate dikinase
KM387_15250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_15265	COG5577	PFAM Coat F domain
KM387_15270	COG3403	YqcI/YcgG family
KM387_15275	COG1280	lysine exporter protein (LysE YggA)
KM387_15310	COG1063	alcohol dehydrogenase
KM387_15325	COG1027	Aspartate ammonia-lyase
KM387_15330	COG0252	asparaginase activity
KM387_15335	COG1396	sequence-specific DNA binding
KM387_15345	COG0322	excinuclease ABC activity
KM387_15355	COG1114	Component of the transport system for branched-chain amino acids
KM387_15360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_15370	COG0281	malic enzyme
KM387_15385	COG0531	amino acid
KM387_15395	COG0784	Response regulator, receiver
KM387_15400	COG4191	Histidine kinase
KM387_15405	COG2066	Belongs to the glutaminase family
KM387_15410	COG1115	amino acid carrier protein
KM387_15440	COG0737	Belongs to the 5'-nucleotidase family
KM387_15445	COG0753	catalase activity
KM387_15450	COG2267	carboxylic ester hydrolase activity
KM387_15455	COG1335	isochorismatase
KM387_15475	COG0583	DNA-binding transcription factor activity
KM387_15480	COG1846	Transcriptional regulator
KM387_15485	COG0598	Magnesium transport protein CorA
KM387_15520	COG0415	Belongs to the DNA photolyase family
KM387_15525	COG0288	reversible hydration of carbon dioxide
KM387_15535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM387_15540	COG5609	conserved protein (DUF2294)
KM387_15555	COG1575	Belongs to the MenA family. Type 1 subfamily
KM387_15560	COG2267	carboxylic ester hydrolase activity
KM387_15565	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM387_15570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM387_15575	COG1121	(ABC) transporter
KM387_15605	COG0798	PFAM Bile acid sodium symporter
KM387_15610	COG0346	lactoylglutathione lyase activity
KM387_15615	COG0640	Transcriptional regulator
KM387_15630	COG0443	Heat shock 70 kDa protein
KM387_15645	COG1522	sequence-specific DNA binding
KM387_15660	COG0346	lactoylglutathione lyase activity
KM387_15680	COG2169	Transcriptional regulator
KM387_15725	COG2814	Major facilitator Superfamily
KM387_15750	COG0745	RESPONSE REGULATOR receiver
KM387_15755	COG3850	Histidine kinase
KM387_15755	COG5002	protein histidine kinase activity
KM387_15780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM387_15800	COG1476	TRANSCRIPTIONal
KM387_15815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_15820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_15830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_15835	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM387_15850	COG1136	(ABC) transporter
KM387_15855	COG0577	efflux transmembrane transporter activity
KM387_15870	COG3850	Histidine kinase
KM387_15870	COG5002	protein histidine kinase activity
KM387_15880	COG2364	Membrane
KM387_15885	COG1846	Transcriptional regulator
KM387_15890	COG0456	acetyltransferase
KM387_15895	COG2808	Putative FMN-binding domain
KM387_15900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_15905	COG2271	Major facilitator Superfamily
KM387_15910	COG1556	Lactate utilization protein
KM387_15915	COG1139	Iron-sulfur cluster binding protein
KM387_15925	COG0583	DNA-binding transcription factor activity
KM387_15935	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_15955	COG0738	Major facilitator superfamily
KM387_15960	COG0673	inositol 2-dehydrogenase activity
KM387_15965	COG0561	phosphatase activity
KM387_15970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM387_15975	COG1609	Transcriptional regulator
KM387_15980	COG0457	Tetratricopeptide repeat
KM387_16000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_16030	COG0534	Mate efflux family protein
KM387_16050	COG2814	Major facilitator Superfamily
KM387_16055	COG1309	transcriptional regulator
KM387_16070	COG0814	amino acid
KM387_16075	COG1760	l-serine dehydratase
KM387_16080	COG1760	l-serine dehydratase
KM387_16090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM387_16095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM387_16105	COG1335	isochorismatase
KM387_16110	COG1522	sequence-specific DNA binding
KM387_16115	COG0531	amino acid
KM387_16130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM387_16150	COG1595	DNA-templated transcription, initiation
KM387_16165	COG0662	Cupin 2, conserved barrel domain protein
KM387_16170	COG2207	Transcriptional regulator
KM387_16170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_16185	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_16185	COG3409	Peptidoglycan-binding domain 1 protein
KM387_16220	COG0477	Major facilitator Superfamily
KM387_16230	COG1846	Transcriptional regulator
KM387_16235	COG2814	Major facilitator Superfamily
KM387_16245	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_16270	COG2076	Multidrug Resistance protein
KM387_16275	COG1309	transcriptional regulator
KM387_16285	COG2031	fatty acid transporter
KM387_16295	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_16325	COG1122	ATPase activity
KM387_16330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM387_16345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM387_16350	COG1288	antiporter activity
KM387_16355	COG2356	endonuclease I
KM387_16370	COG3620	sequence-specific DNA binding
KM387_16375	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_16380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM387_16385	COG0124	histidyl-tRNA synthetase
KM387_16400	COG1733	regulation of RNA biosynthetic process
KM387_16405	COG0778	Nitroreductase
KM387_16425	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_16435	COG1131	(ABC) transporter
KM387_16460	COG1011	Hydrolase
KM387_16470	COG2365	Tyrosine phosphatase family
KM387_16495	COG0346	lactoylglutathione lyase activity
KM387_16500	COG1940	carbohydrate kinase activity
KM387_16505	COG0738	Major facilitator superfamily
KM387_16510	COG0110	maltose O-acetyltransferase activity
KM387_16520	COG0577	efflux transmembrane transporter activity
KM387_16520	COG1136	(ABC) transporter
KM387_16540	COG0628	permease
KM387_16560	COG2226	methyltransferase
KM387_16570	COG0477	Major facilitator Superfamily
KM387_16600	COG1253	flavin adenine dinucleotide binding
KM387_16605	COG0789	Transcriptional regulator
KM387_16610	COG0697	spore germination
KM387_16615	COG1357	PFAM Pentapeptide repeats (8 copies)
KM387_16620	COG3813	Protein conserved in bacteria
KM387_16625	COG2706	6-phosphogluconolactonase activity
KM387_16630	COG1070	Carbohydrate kinase
KM387_16640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM387_16645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM387_16655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM387_16660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM387_16665	COG0604	alcohol dehydrogenase
KM387_16670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_16685	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_16710	COG0656	L-ascorbic acid biosynthetic process
KM387_16715	COG2814	Major facilitator Superfamily
KM387_16730	COG0346	lactoylglutathione lyase activity
KM387_16735	COG0814	amino acid
KM387_16760	COG1393	Belongs to the ArsC family
KM387_16765	COG1733	regulation of RNA biosynthetic process
KM387_16770	COG2188	Transcriptional regulator
KM387_16775	COG0673	inositol 2-dehydrogenase activity
KM387_16780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM387_16785	COG1733	regulation of RNA biosynthetic process
KM387_16790	COG1733	regulation of RNA biosynthetic process
KM387_16805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_16825	COG0384	phenazine biosynthesis protein PhzF
KM387_16835	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_16855	COG1733	regulation of RNA biosynthetic process
KM387_16885	COG1191	sigma factor activity
KM387_16900	COG1309	transcriptional regulator
KM387_16920	COG3152	Membrane
KM387_16945	COG1151	hydroxylamine reductase activity
KM387_16955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_16960	COG3757	hydrolase, family 25
KM387_16960	COG3409	Peptidoglycan-binding domain 1 protein
KM387_16995	COG2072	flavoprotein involved in K transport
KM387_17030	COG0604	alcohol dehydrogenase
KM387_17035	COG1113	amino acid transport
KM387_17040	COG2814	Major facilitator Superfamily
KM387_17070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_17075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_17095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_17110	COG3739	integral membrane protein
KM387_17115	COG0384	phenazine biosynthesis protein PhzF
KM387_17145	COG0583	DNA-binding transcription factor activity
KM387_17165	COG1193	negative regulation of DNA recombination
KM387_17180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM387_17185	COG1164	Oligoendopeptidase f
KM387_17190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_17220	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_17245	COG0640	Transcriptional regulator
KM387_17250	COG0604	alcohol dehydrogenase
KM387_17260	COG0457	Tetratricopeptide repeat
KM387_17270	COG2808	Putative FMN-binding domain
KM387_17275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_17285	COG0385	Bile acid
KM387_17290	COG0277	FAD linked oxidase domain protein
KM387_17320	COG1216	Glycosyl transferase, family 2
KM387_17325	COG1024	Enoyl-CoA hydratase
KM387_17335	COG1285	pathogenesis
KM387_17350	COG2514	catechol 2,3-dioxygenase activity
KM387_17355	COG2720	vancomycin resistance protein
KM387_17395	COG0716	FMN binding
KM387_17425	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_17435	COG0165	Argininosuccinate lyase
KM387_17450	COG4145	pantothenate transmembrane transporter activity
KM387_17460	COG1012	belongs to the aldehyde dehydrogenase family
KM387_17465	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_17475	COG1657	PFAM Prenyltransferase squalene oxidase
KM387_17480	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM387_17485	COG2962	Rard protein
KM387_17490	COG3326	Membrane
KM387_17505	COG0489	protein tyrosine kinase activity
KM387_17515	COG0314	molybdopterin synthase activity
KM387_17520	COG0303	'Molybdopterin
KM387_17525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_17530	COG2116	formate transmembrane transporter activity
KM387_17540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM387_17545	COG5609	conserved protein (DUF2294)
KM387_17550	COG2427	Protein of unknown function (DUF1641)
KM387_17555	COG3383	formate dehydrogenase (NAD+) activity
KM387_17560	COG0697	spore germination
KM387_17600	COG2226	methyltransferase
KM387_17605	COG4166	transmembrane transport
KM387_17610	COG4166	transmembrane transport
KM387_17615	COG4166	transmembrane transport
KM387_17620	COG1301	dicarboxylic acid transport
KM387_17625	COG1316	TRANSCRIPTIONal
KM387_17635	COG1595	DNA-templated transcription, initiation
KM387_17650	COG1131	(ABC) transporter
KM387_17660	COG0673	inositol 2-dehydrogenase activity
KM387_17665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM387_17670	COG0187	DNA topoisomerase II activity
KM387_17675	COG1832	CoA-binding protein
KM387_17680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_17685	COG0745	RESPONSE REGULATOR receiver
KM387_17700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_17705	COG4841	protein insertion into membrane
KM387_17710	COG0824	Thioesterase
KM387_17740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_17750	COG2274	protein secretion by the type I secretion system
KM387_17755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM387_17795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_17815	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_17820	COG1268	BioY protein
KM387_17825	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_17875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_17885	COG5002	protein histidine kinase activity
KM387_17890	COG0400	carboxylic ester hydrolase activity
KM387_17895	COG0346	lactoylglutathione lyase activity
KM387_17900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_17905	COG0069	glutamate synthase activity
KM387_17910	COG1902	pentaerythritol trinitrate reductase activity
KM387_17915	COG1329	Transcriptional regulator
KM387_17920	COG0010	Belongs to the arginase family
KM387_17945	COG2226	methyltransferase
KM387_17980	COG4846	Membrane protein involved in cytochrome C biogenesis
KM387_17985	COG0785	Cytochrome C biogenesis protein
KM387_17995	COG1473	amidohydrolase
KM387_18005	COG1131	(ABC) transporter
KM387_18015	COG0583	DNA-binding transcription factor activity
KM387_18025	COG1346	cytolysis
KM387_18050	COG3409	Peptidoglycan-binding domain 1 protein
KM387_18050	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_18065	COG1132	(ABC) transporter
KM387_18070	COG1132	(ABC) transporter
KM387_18100	COG3639	organic phosphonate transmembrane transporter activity
KM387_18105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM387_18125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM387_18145	COG1695	Transcriptional regulator
KM387_18180	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_18180	COG1388	LysM domain
KM387_18180	COG3409	Peptidoglycan-binding domain 1 protein
KM387_18185	COG4824	toxin secretion phage lysis holin
KM387_18335	COG1595	DNA-templated transcription, initiation
KM387_18380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM387_18460	COG1396	sequence-specific DNA binding
KM387_18480	COG0174	glutamine synthetase
KM387_18485	COG0789	Transcriptional regulator
KM387_18490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM387_18495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM387_18500	COG2860	membrane
KM387_18505	COG0464	growth
KM387_18535	COG3584	3D domain protein
KM387_18535	COG1388	LysM domain
KM387_18545	COG1105	Belongs to the carbohydrate kinase PfkB family
KM387_18550	COG1349	DNA-binding transcription factor activity
KM387_18560	COG2322	membrane
KM387_18570	COG1113	amino acid transport
KM387_18585	COG1408	metallophosphoesterase
KM387_18590	COG2116	formate transmembrane transporter activity
KM387_18600	COG2217	Heavy metal translocating P-type atpase
KM387_18605	COG2608	mercury ion transmembrane transporter activity
KM387_18610	COG1937	Protein conserved in bacteria
KM387_18620	COG2819	hydrolase of the alpha beta superfamily
KM387_18625	COG1120	ATPase activity
KM387_18630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_18635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_18645	COG0708	Exodeoxyribonuclease III
KM387_18650	COG2169	Transcriptional regulator
KM387_18655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM387_18660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM387_18670	COG2364	Membrane
KM387_18685	COG2267	carboxylic ester hydrolase activity
KM387_18690	COG0346	lactoylglutathione lyase activity
KM387_18695	COG5001	Diguanylate cyclase
KM387_18695	COG3300	MHYT domain
KM387_18710	COG1346	cytolysis
KM387_18715	COG1380	Effector of murein hydrolase LrgA
KM387_18720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_18725	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_18725	COG0596	Alpha beta hydrolase
KM387_18730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_18750	COG1404	Belongs to the peptidase S8 family
KM387_18755	COG3773	Cell wall hydrolase
KM387_18760	COG0562	UDP-galactopyranose mutase
KM387_18765	COG1368	sulfuric ester hydrolase activity
KM387_18770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_18780	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM387_18805	COG1131	(ABC) transporter
KM387_18825	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM387_18830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM387_18835	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM387_18840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM387_18840	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM387_18850	COG2359	stage V sporulation protein S
KM387_18855	COG1692	metallophosphoesterase
KM387_18880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM387_18885	COG1426	Protein conserved in bacteria
KM387_18900	COG0300	oxidoreductase activity
KM387_18905	COG0612	Peptidase, M16
KM387_18910	COG0612	Peptidase, M16
KM387_18915	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM387_18925	COG3845	ABC transporter
KM387_18930	COG1744	ABC transporter substrate-binding protein PnrA-like
KM387_18935	COG2188	Transcriptional regulator
KM387_18940	COG1674	ftsk spoiiie
KM387_18950	COG0740	serine-type endopeptidase activity
KM387_18955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_18970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM387_18975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM387_18980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM387_18985	COG1873	PFAM PRC-barrel domain
KM387_18990	COG0612	Peptidase, M16
KM387_18995	COG0726	polysaccharide deacetylase
KM387_19010	COG0196	riboflavin kinase activity
KM387_19015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM387_19025	COG1550	Protein conserved in bacteria
KM387_19035	COG1358	cellular component organization or biogenesis
KM387_19040	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM387_19045	COG0195	Participates in both transcription termination and antitermination
KM387_19065	COG0750	zinc metalloprotease
KM387_19075	COG4589	Belongs to the CDS family
KM387_19090	COG0528	UMP kinase activity
KM387_19120	COG4974	Belongs to the 'phage' integrase family
KM387_19130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_19135	COG0758	DNA mediated transformation
KM387_19140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM387_19180	COG1837	Belongs to the UPF0109 family
KM387_19190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM387_19200	COG0552	protein localization to endoplasmic reticulum
KM387_19205	COG1196	nuclear chromosome segregation
KM387_19215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_19220	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_19225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM387_19240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM387_19245	COG1461	Dihydroxyacetone kinase
KM387_19250	COG1302	Protein conserved in bacteria
KM387_19265	COG1564	THIamine pyrophosphokinase
KM387_19270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM387_19275	COG1162	GTPase activity
KM387_19280	COG0515	serine threonine protein kinase
KM387_19280	COG2815	serine threonine protein kinase
KM387_19285	COG0631	protein serine/threonine phosphatase activity
KM387_19295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM387_19295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM387_19305	COG0242	peptide deformylase activity
KM387_19310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM387_19315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM387_19335	COG1561	YicC-like family, N-terminal region
KM387_19340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM387_19350	COG0006	proline dipeptidase activity
KM387_19365	COG3069	C4-dicarboxylate transmembrane transporter activity
KM387_19430	COG0564	pseudouridine synthase activity
KM387_19450	COG3599	regulation of cell shape
KM387_19455	COG2302	S4 RNA-binding domain
KM387_19460	COG0762	integral membrane protein
KM387_19470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM387_19475	COG1496	oxidoreductase activity
KM387_19480	COG1873	PFAM PRC-barrel domain
KM387_19485	COG1191	sigma factor activity
KM387_19490	COG1191	sigma factor activity
KM387_19500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM387_19505	COG0849	cell division
KM387_19510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM387_19515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM387_19525	COG0772	Belongs to the SEDS family
KM387_19540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM387_19545	COG0768	penicillin binding
KM387_19550	COG0768	penicillin binding
KM387_19555	COG4839	cell division protein FtsL
KM387_19570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM387_19585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM387_19590	COG1399	metal-binding, possibly nucleic acid-binding protein
KM387_19640	COG4824	toxin secretion phage lysis holin
KM387_19725	COG4626	Terminase
KM387_19725	COG1802	Transcriptional regulator
KM387_19750	COG0582	viral genome integration into host DNA
KM387_19815	COG0756	dUTP diphosphatase activity
KM387_19830	COG1191	sigma factor activity
KM387_19855	COG1484	DNA-dependent DNA replication
KM387_19885	COG1396	sequence-specific DNA binding
KM387_19900	COG1396	sequence-specific DNA binding
KM387_19915	COG0582	viral genome integration into host DNA
KM387_19925	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM387_19930	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM387_19935	COG3314	Sporulation integral membrane protein YlbJ
KM387_19945	COG0742	ribosomal rna small subunit methyltransferase
KM387_19965	COG0406	alpha-ribazole phosphatase activity
KM387_19980	COG2340	Cysteine-rich secretory protein family
KM387_19995	COG3336	cytochrome c oxidase
KM387_20030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM387_20035	COG0772	Belongs to the SEDS family
KM387_20045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM387_20050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM387_20060	COG4896	Protein conserved in bacteria
KM387_20075	COG1217	gtp-binding protein TYPA
KM387_20085	COG0483	inositol monophosphate 1-phosphatase activity
KM387_20105	COG1982	Orn Lys Arg decarboxylase major
KM387_20155	COG0022	dehydrogenase e1 component
KM387_20160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_20170	COG0242	peptide deformylase activity
KM387_20175	COG0561	phosphatase activity
KM387_20185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_20190	COG0569	domain protein
KM387_20210	COG0583	DNA-binding transcription factor activity
KM387_20215	COG0517	IMP dehydrogenase activity
KM387_20225	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM387_20235	COG4703	Protein of unknown function (DUF1797)
KM387_20250	COG2200	EAL domain
KM387_20255	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_20260	COG1408	metallophosphoesterase
KM387_20270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM387_20305	COG2814	Major facilitator Superfamily
KM387_20325	COG3209	COG3209 Rhs family protein
KM387_20335	COG2205	protein histidine kinase activity
KM387_20345	COG0436	Aminotransferase
KM387_20350	COG1609	Transcriptional regulator
KM387_20355	COG3833	ABC-type maltose transport systems, permease component
KM387_20360	COG1175	transmembrane transport
KM387_20365	COG2182	Extracellular solute-binding protein
KM387_20375	COG0366	Alpha amylase catalytic
KM387_20380	COG3842	ATPase activity
KM387_20420	COG0183	Belongs to the thiolase family
KM387_20455	COG1695	Transcriptional regulator
KM387_20460	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_20470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM387_20480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM387_20485	COG0436	Aminotransferase
KM387_20525	COG2199	diguanylate cyclase activity
KM387_20530	COG0778	Nitroreductase
KM387_20555	COG2190	(PTS) system
KM387_20555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_20555	COG1263	PTS System
KM387_20560	COG3711	transcriptional antiterminator
KM387_20570	COG2188	Transcriptional regulator
KM387_20580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM387_20605	COG1547	Domain of unknown function (DUF309)
KM387_20610	COG0456	acetyltransferase
KM387_20615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM387_20620	COG4086	secreted protein
KM387_20625	COG0561	phosphatase activity
KM387_20630	COG0697	spore germination
KM387_20645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_20670	COG0733	neurotransmitter:sodium symporter activity
KM387_20690	COG1686	Belongs to the peptidase S11 family
KM387_20695	COG1725	Transcriptional regulator
KM387_20700	COG1131	(ABC) transporter
KM387_20715	COG1846	Transcriptional regulator
KM387_20730	COG0598	Magnesium transport protein CorA
KM387_20755	COG4974	Belongs to the 'phage' integrase family
KM387_20765	COG0735	belongs to the Fur family
KM387_20770	COG1300	Membrane
KM387_20790	COG0667	Aldo Keto reductase
KM387_20795	COG0656	L-ascorbic acid biosynthetic process
KM387_20800	COG0456	acetyltransferase
KM387_20800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_20810	COG1525	nuclease
KM387_20810	COG0737	Belongs to the 5'-nucleotidase family
KM387_20810	COG4085	toxin activity
KM387_20820	COG0596	Alpha beta hydrolase
KM387_20825	COG2056	Na+-H+ antiporter family
KM387_20830	COG1609	Transcriptional regulator
KM387_20835	COG0456	acetyltransferase
KM387_20840	COG1073	alpha beta
KM387_20855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM387_20855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM387_20860	COG0307	riboflavin synthase, alpha
KM387_20885	COG4106	trans-aconitate 2-methyltransferase activity
KM387_20890	COG1073	alpha beta
KM387_20890	COG2226	methyltransferase
KM387_20905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_20915	COG1757	Na H antiporter
KM387_20920	COG0737	Belongs to the 5'-nucleotidase family
KM387_20930	COG1522	sequence-specific DNA binding
KM387_20950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM387_20960	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM387_20975	COG0300	oxidoreductase activity
KM387_20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_20985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_20990	COG1760	l-serine dehydratase
KM387_20995	COG1760	l-serine dehydratase
KM387_21015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_21025	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM387_21030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_21045	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_21050	COG4129	membrane
KM387_21055	COG1126	abc transporter atp-binding protein
KM387_21060	COG0765	amino acid transport
KM387_21065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_21080	COG2816	NAD+ diphosphatase activity
KM387_21085	COG0772	Belongs to the SEDS family
KM387_21090	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_21095	COG0022	dehydrogenase e1 component
KM387_21100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_21105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM387_21120	COG0280	phosphate acetyltransferase
KM387_21125	COG3829	transcription factor binding
KM387_21125	COG3290	protein histidine kinase activity
KM387_21135	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_21140	COG3093	addiction module antidote protein HigA
KM387_21150	COG0745	RESPONSE REGULATOR receiver
KM387_21155	COG0750	zinc metalloprotease
KM387_21160	COG0497	DNA recombination
KM387_21170	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM387_21180	COG0142	geranyltranstransferase activity
KM387_21205	COG1302	Protein conserved in bacteria
KM387_21210	COG0439	Biotin carboxylase
KM387_21215	COG0511	ligase activity, forming carbon-carbon bonds
KM387_21260	COG3854	ATPases associated with a variety of cellular activities
KM387_21285	COG0006	proline dipeptidase activity
KM387_21300	COG3872	metal-dependent enzyme
KM387_21310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM387_21330	COG0095	Lipoate-protein ligase
KM387_21335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_21340	COG1609	Transcriptional regulator
KM387_21350	COG2076	Multidrug Resistance protein
KM387_21355	COG2076	Multidrug Resistance protein
KM387_21390	COG1131	(ABC) transporter
KM387_21395	COG1725	Transcriptional regulator
KM387_21425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_21480	COG4970	Tfp pilus assembly protein FimT
KM387_21490	COG1459	type II secretion system
KM387_21495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM387_21545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM387_21550	COG0646	methionine synthase
KM387_21550	COG1410	methionine synthase
KM387_21555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM387_21555	COG0646	methionine synthase
KM387_21560	COG0626	cystathionine gamma-synthase activity
KM387_21565	COG0626	cystathionine gamma-synthase activity
KM387_21585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_21600	COG4483	Protein conserved in bacteria
KM387_21605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM387_21610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM387_21615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM387_21620	COG0704	Plays a role in the regulation of phosphate uptake
KM387_21630	COG0581	inorganic phosphate transmembrane transporter activity
KM387_21635	COG0573	inorganic phosphate transmembrane transporter activity
KM387_21640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM387_21645	COG0768	penicillin binding
KM387_21650	COG0477	Major facilitator Superfamily
KM387_21655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_21680	COG0735	belongs to the Fur family
KM387_21685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM387_21690	COG1121	(ABC) transporter
KM387_21695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_21725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM387_21730	COG2384	SAM-dependent methyltransferase
KM387_21735	COG2010	Cytochrome c
KM387_21740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM387_21745	COG0358	DNA primase activity
KM387_21760	COG0517	IMP dehydrogenase activity
KM387_21775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM387_21780	COG0295	cytidine deaminase activity
KM387_21785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM387_21795	COG1480	7TM receptor with intracellular HD hydrolase
KM387_21800	COG1702	phosphate starvation-inducible protein PhoH
KM387_21815	COG1610	YqeY-like protein
KM387_21820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM387_21825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM387_21830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM387_21860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM387_21865	COG1733	regulation of RNA biosynthetic process
KM387_21890	COG1466	dna polymerase III delta subunit
KM387_21900	COG2333	competence protein COMEC
KM387_21900	COG0658	competence protein
KM387_21905	COG2131	deaminase
KM387_21910	COG1596	polysaccharide export
KM387_21910	COG1555	photosystem II stabilization
KM387_21915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_21920	COG2226	methyltransferase
KM387_21925	COG0799	negative regulation of ribosome biogenesis
KM387_21930	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM387_21940	COG1534	Rna-binding protein
KM387_21950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM387_21955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM387_21980	COG1595	DNA-templated transcription, initiation
KM387_21990	COG0778	Nitroreductase
KM387_22005	COG1785	Belongs to the alkaline phosphatase family
KM387_22015	COG2267	carboxylic ester hydrolase activity
KM387_22050	COG1404	Belongs to the peptidase S8 family
KM387_22055	COG3186	Phenylalanine-4-hydroxylase
KM387_22065	COG2514	catechol 2,3-dioxygenase activity
KM387_22070	COG2259	Doxx family
KM387_22110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_22120	COG1454	alcohol dehydrogenase
KM387_22120	COG1012	belongs to the aldehyde dehydrogenase family
KM387_22125	COG0626	cystathionine gamma-synthase activity
KM387_22130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_22155	COG0768	penicillin binding
KM387_22170	COG0826	peptidase U32
KM387_22175	COG0826	peptidase U32
KM387_22180	COG4122	O-methyltransferase activity
KM387_22185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM387_22205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_22215	COG0628	permease
KM387_22235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM387_22250	COG1104	cysteine desulfurase activity
KM387_22255	COG1959	2 iron, 2 sulfur cluster binding
KM387_22260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM387_22270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM387_22295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM387_22305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM387_22305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM387_22310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM387_22315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM387_22315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM387_22325	COG2244	polysaccharide biosynthetic process
KM387_22330	COG2323	membrane
KM387_22340	COG1862	Preprotein translocase
KM387_22370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM387_22380	COG0697	spore germination
KM387_22385	COG0697	spore germination
KM387_22390	COG0640	Transcriptional regulator
KM387_22415	COG0157	Belongs to the NadC ModD family
KM387_22420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM387_22425	COG1104	cysteine desulfurase activity
KM387_22430	COG1827	regulation of RNA biosynthetic process
KM387_22435	COG2258	MOSC domain
KM387_22440	COG0077	Prephenate dehydratase
KM387_22445	COG0577	efflux transmembrane transporter activity
KM387_22450	COG0577	efflux transmembrane transporter activity
KM387_22455	COG1136	(ABC) transporter
KM387_22465	COG0745	RESPONSE REGULATOR receiver
KM387_22475	COG3290	protein histidine kinase activity
KM387_22485	COG2868	ribosomal protein
KM387_22495	COG1530	ribonuclease E activity
KM387_22500	COG1994	Peptidase M50
KM387_22505	COG0739	heme binding
KM387_22510	COG2894	cell division
KM387_22530	COG1077	Cell shape determining protein MreB Mrl
KM387_22550	COG0285	dihydrofolate synthase activity
KM387_22555	COG0525	valine-tRNA ligase activity
KM387_22565	COG1388	LysM domain
KM387_22575	COG0113	porphobilinogen synthase activity
KM387_22580	COG1587	Uroporphyrinogen-III synthase
KM387_22590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM387_22600	COG1846	Transcriptional regulator
KM387_22605	COG1764	response to oxidative stress
KM387_22620	COG0470	DNA polymerase III
KM387_22620	COG1067	ATP-dependent peptidase activity
KM387_22665	COG0622	Phosphoesterase
KM387_22680	COG5401	PFAM Sporulation and spore germination
KM387_22700	COG1309	transcriptional regulator
KM387_22715	COG2197	response regulator
KM387_22720	COG2233	PERMEase
KM387_22730	COG0402	S-adenosylhomocysteine deaminase activity
KM387_22735	COG0402	S-adenosylhomocysteine deaminase activity
KM387_22745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_22755	COG0444	Belongs to the ABC transporter superfamily
KM387_22760	COG4608	Belongs to the ABC transporter superfamily
KM387_22765	COG3275	phosphorelay sensor kinase activity
KM387_22770	COG3279	Response regulator of the LytR AlgR family
KM387_22780	COG1983	PspC domain protein
KM387_22785	COG1396	sequence-specific DNA binding
KM387_22790	COG0697	spore germination
KM387_22800	COG1959	2 iron, 2 sulfur cluster binding
KM387_22805	COG1668	transmembrane transport
KM387_22810	COG4152	abc transporter atp-binding protein
KM387_22815	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM387_22825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM387_22830	COG1876	peptidase activity
KM387_22835	COG0824	Thioesterase
KM387_22840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM387_22845	COG1053	succinate dehydrogenase
KM387_22850	COG2009	succinate dehydrogenase
KM387_22855	COG1719	4-vinyl reductase, 4VR
KM387_22865	COG3118	belongs to the thioredoxin family
KM387_22870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM387_22875	COG2086	electron transfer activity
KM387_22880	COG1024	Enoyl-CoA hydratase
KM387_22885	COG1309	transcriptional regulator
KM387_22890	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_22910	COG2318	DinB family
KM387_22940	COG1131	(ABC) transporter
KM387_22945	COG2205	protein histidine kinase activity
KM387_22950	COG0745	RESPONSE REGULATOR receiver
KM387_22960	COG4895	conserved protein (DUF2196)
KM387_22965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM387_22980	COG4509	Sortase family
KM387_22985	COG1120	ATPase activity
KM387_23000	COG5386	Cell surface protein
KM387_23010	COG5386	Cell surface protein
KM387_23015	COG1114	Component of the transport system for branched-chain amino acids
KM387_23020	COG1187	pseudouridine synthase activity
KM387_23030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM387_23030	COG1796	DNA polymerase
KM387_23035	COG1286	toxin biosynthetic process
KM387_23080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM387_23090	COG1418	mRNA catabolic process
KM387_23115	COG2814	Major facilitator Superfamily
KM387_23120	COG1566	PFAM secretion protein HlyD family protein
KM387_23125	COG1309	transcriptional regulator
KM387_23130	COG1363	Peptidase, m42
KM387_23155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM387_23165	COG1484	DNA-dependent DNA replication
KM387_23170	COG3611	Membrane attachment protein
KM387_23180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM387_23185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM387_23190	COG0237	dephospho-CoA kinase activity
KM387_23195	COG1971	Probably functions as a manganese efflux pump
KM387_23205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_23205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_23210	COG5002	protein histidine kinase activity
KM387_23215	COG0745	RESPONSE REGULATOR receiver
KM387_23235	COG0538	isocitrate dehydrogenase activity
KM387_23240	COG0372	Belongs to the citrate synthase family
KM387_23250	COG0628	permease
KM387_23255	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM387_23280	COG1725	Transcriptional regulator
KM387_23285	COG0281	malic enzyme
KM387_23290	COG0587	DNA-directed DNA polymerase activity
KM387_23305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM387_23325	COG4109	DRTGG domain
KM387_23340	COG0006	proline dipeptidase activity
KM387_23375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_23380	COG0662	Cupin 2, conserved barrel domain protein
KM387_23390	COG1476	TRANSCRIPTIONal
KM387_23405	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_23450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_23470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM387_23475	COG0827	DNA restriction-modification system
KM387_23480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM387_23485	COG3874	Sporulation protein YtfJ
KM387_23500	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM387_23510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_23525	COG1104	cysteine desulfurase activity
KM387_23535	COG0583	DNA-binding transcription factor activity
KM387_23540	COG0697	spore germination
KM387_23545	COG1309	transcriptional regulator
KM387_23550	COG1956	GAF domain-containing protein
KM387_23555	COG0626	cystathionine gamma-synthase activity
KM387_23585	COG1595	DNA-templated transcription, initiation
KM387_23595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_23600	COG0454	-acetyltransferase
KM387_23605	COG0517	IMP dehydrogenase activity
KM387_23610	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM387_23620	COG0745	RESPONSE REGULATOR receiver
KM387_23630	COG0666	response to abiotic stimulus
KM387_23665	COG1609	Transcriptional regulator
KM387_23670	COG4851	CamS sex pheromone cAM373 precursor
KM387_23675	COG3118	belongs to the thioredoxin family
KM387_23685	COG2309	aminopeptidase activity
KM387_23705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_23720	COG1674	ftsk spoiiie
KM387_23730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_23735	COG4848	Belongs to the UPF0354 family
KM387_23740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_23745	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM387_23750	COG1363	Peptidase, m42
KM387_23760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_23775	COG0510	thiamine kinase activity
KM387_23780	COG1523	belongs to the glycosyl hydrolase 13 family
KM387_23790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_23795	COG1349	DNA-binding transcription factor activity
KM387_23800	COG1187	pseudouridine synthase activity
KM387_23805	COG2244	polysaccharide biosynthetic process
KM387_23815	COG2814	Major facilitator Superfamily
KM387_23825	COG3832	glyoxalase III activity
KM387_23845	COG1329	Transcriptional regulator
KM387_23870	COG0314	molybdopterin synthase activity
KM387_23875	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM387_23880	COG0303	'Molybdopterin
KM387_23890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_23895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM387_23915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_23925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM387_23965	COG2814	Major facilitator Superfamily
KM387_23970	COG0475	glutathione-regulated potassium exporter activity
KM387_23975	COG0490	domain, Protein
KM387_23980	COG0582	viral genome integration into host DNA
KM387_23990	COG1136	(ABC) transporter
KM387_24010	COG1242	4 iron, 4 sulfur cluster binding
KM387_24015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM387_24020	COG1131	(ABC) transporter
KM387_24030	COG1794	racemase activity, acting on amino acids and derivatives
KM387_24050	COG2267	carboxylic ester hydrolase activity
KM387_24055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM387_24060	COG0671	phosphoesterase, PA-phosphatase related
KM387_24065	COG0438	transferase activity, transferring glycosyl groups
KM387_24075	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM387_24130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM387_24135	COG5002	protein histidine kinase activity
KM387_24140	COG4191	Histidine kinase
KM387_24145	COG2267	carboxylic ester hydrolase activity
KM387_24150	COG1368	sulfuric ester hydrolase activity
KM387_24165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_24170	COG1116	anion transmembrane transporter activity
KM387_24175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_24200	COG0494	nUDIX hydrolase
KM387_24230	COG0288	reversible hydration of carbon dioxide
KM387_24235	COG1271	oxidase subunit
KM387_24240	COG1294	oxidase, subunit
KM387_24260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_24285	COG1842	Phage shock protein A
KM387_24315	COG5002	protein histidine kinase activity
KM387_24320	COG0745	RESPONSE REGULATOR receiver
KM387_24345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM387_24350	COG1597	lipid kinase activity
KM387_24385	COG0586	Pfam SNARE associated Golgi protein
KM387_24395	COG0577	efflux transmembrane transporter activity
KM387_24400	COG1136	(ABC) transporter
KM387_24405	COG3708	Transcriptional regulator
KM387_24405	COG2207	Transcriptional regulator
KM387_24410	COG0745	RESPONSE REGULATOR receiver
KM387_24415	COG2205	protein histidine kinase activity
KM387_24420	COG0577	efflux transmembrane transporter activity
KM387_24425	COG0577	efflux transmembrane transporter activity
KM387_24430	COG1136	(ABC) transporter
KM387_24435	COG0577	efflux transmembrane transporter activity
KM387_24450	COG2188	Transcriptional regulator
KM387_24470	COG3964	amidohydrolase
KM387_24500	COG4948	Mandelate Racemase Muconate Lactonizing
KM387_24510	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM387_24515	COG0596	Alpha beta hydrolase
KM387_24520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM387_24525	COG1169	isochorismate synthase
KM387_24530	COG1575	Belongs to the MenA family. Type 1 subfamily
KM387_24535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM387_24555	COG0058	SHG alpha-glucan phosphorylase activity
KM387_24560	COG0297	glycogen (starch) synthase activity
KM387_24565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM387_24685	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM387_24720	COG1285	pathogenesis
KM387_24725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM387_24735	COG0166	Belongs to the GPI family
KM387_24740	COG2155	Conserved Protein
KM387_24745	COG1098	S1 RNA binding domain
KM387_24750	COG0436	Aminotransferase
KM387_24755	COG1522	sequence-specific DNA binding
KM387_24760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM387_24765	COG2267	carboxylic ester hydrolase activity
KM387_24775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM387_24795	COG5018	Exonuclease
KM387_24800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_24820	COG2050	protein possibly involved in aromatic compounds catabolism
KM387_24830	COG1268	BioY protein
KM387_24840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM387_24845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM387_24860	COG3584	3D domain protein
KM387_24875	COG1252	NADH dehydrogenase
KM387_24890	COG3708	Transcriptional regulator
KM387_24905	COG1683	Conserved Protein
KM387_24925	COG0316	Belongs to the HesB IscA family
KM387_24940	COG1252	NADH dehydrogenase
KM387_24950	COG2274	protein secretion by the type I secretion system
KM387_24955	COG0390	transport system, permease component
KM387_24960	COG2824	Alkylphosphonate utilization operon protein PhnA
KM387_25000	COG4837	Protein of unknown function (DUF1462)
KM387_25005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM387_25015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_25020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM387_25030	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_25035	COG0647	UMP catabolic process
KM387_25045	COG2445	Protein of unknown function DUF86
KM387_25050	COG1494	fructose-1,6-bisphosphatase
KM387_25065	COG4470	Protein conserved in bacteria
KM387_25075	COG0789	Transcriptional regulator
KM387_25080	COG4377	Putative membrane peptidase family (DUF2324)
KM387_25105	COG0739	heme binding
KM387_25115	COG3377	Domain of unknown function (DUF1805)
KM387_25120	COG0737	Belongs to the 5'-nucleotidase family
KM387_25125	COG1695	Transcriptional regulator
KM387_25135	COG0719	Fe-S assembly protein
KM387_25140	COG0822	iron-sulfur transferase activity
KM387_25145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM387_25150	COG0719	Fe-S assembly protein
KM387_25155	COG0396	ATPase activity
KM387_25160	COG1464	Belongs to the NlpA lipoprotein family
KM387_25165	COG1464	Belongs to the NlpA lipoprotein family
KM387_25170	COG2011	ABC-type metal ion transport system permease component
KM387_25175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_25185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_25190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM387_25200	COG1393	Belongs to the ArsC family
KM387_25245	COG0039	L-malate dehydrogenase activity
KM387_25265	COG1309	transcriptional regulator
KM387_25270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_25275	COG1960	acyl-CoA dehydrogenase activity
KM387_25285	COG0183	Belongs to the thiolase family
KM387_25290	COG1024	Enoyl-CoA hydratase
KM387_25290	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM387_25300	COG1686	Belongs to the peptidase S11 family
KM387_25315	COG0011	TIGRFAM Protein of
KM387_25320	COG0840	transmembrane signaling receptor activity
KM387_25340	COG2814	Major facilitator Superfamily
KM387_25345	COG0531	amino acid
KM387_25355	COG0706	membrane insertase activity
KM387_25365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_25400	COG0586	Pfam SNARE associated Golgi protein
KM387_25410	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_25415	COG0745	RESPONSE REGULATOR receiver
KM387_25420	COG5002	protein histidine kinase activity
KM387_25445	COG2151	metal-sulfur cluster biosynthetic enzyme
KM387_25450	COG3227	Zinc metalloprotease (Elastase)
KM387_25455	COG1741	Belongs to the pirin family
KM387_25470	COG0475	glutathione-regulated potassium exporter activity
KM387_25475	COG0490	domain, Protein
KM387_25480	COG1115	amino acid carrier protein
KM387_25485	COG0783	Belongs to the Dps family
KM387_25500	COG1611	Belongs to the LOG family
KM387_25520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_25525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_25530	COG1115	amino acid carrier protein
KM387_25535	COG1115	amino acid carrier protein
KM387_25540	COG2910	NAD(P)H-binding
KM387_25555	COG0656	L-ascorbic acid biosynthetic process
KM387_25560	COG2814	Major facilitator Superfamily
KM387_25565	COG1733	regulation of RNA biosynthetic process
KM387_25575	COG1252	NADH dehydrogenase
KM387_25580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM387_25585	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM387_25595	COG3290	protein histidine kinase activity
KM387_25595	COG0840	transmembrane signaling receptor activity
KM387_25605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM387_25610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM387_25625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_25680	COG0557	exoribonuclease II activity
KM387_25685	COG1647	Serine aminopeptidase, S33
KM387_25690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM387_25695	COG1346	cytolysis
KM387_25795	COG4695	Portal protein
KM387_25815	COG4974	Belongs to the 'phage' integrase family
KM387_25830	COG0149	triose-phosphate isomerase activity
KM387_25840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM387_25855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM387_25880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_25895	COG2323	membrane
KM387_25905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM387_25915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM387_25925	COG1051	belongs to the nudix hydrolase family
KM387_25935	COG0492	ferredoxin-NADP+ reductase activity
KM387_25940	COG0457	Tetratricopeptide repeat
KM387_25945	COG0110	maltose O-acetyltransferase activity
KM387_25965	COG1950	PFAM Membrane protein of
KM387_25975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_25980	COG0556	nucleotide-excision repair
KM387_26000	COG0789	Transcriptional regulator
KM387_26025	COG2855	membrane
KM387_26030	COG0583	DNA-binding transcription factor activity
KM387_26040	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM387_26045	COG0488	(ABC) transporter
KM387_26055	COG1132	(ABC) transporter
KM387_26060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_26065	COG0793	Belongs to the peptidase S41A family
KM387_26065	COG3409	Peptidoglycan-binding domain 1 protein
KM387_26070	COG2177	Part of the ABC transporter FtsEX involved in
KM387_26075	COG2884	Cell division ATP-binding protein ftsE
KM387_26090	COG0653	protein targeting
KM387_26095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM387_26100	COG1278	Cold shock
KM387_26105	COG1040	competence protein
KM387_26110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM387_26115	COG0791	NLP P60 protein
KM387_26115	COG1388	LysM domain
KM387_26120	COG1733	regulation of RNA biosynthetic process
KM387_26125	COG1307	EDD domain protein, DegV family
KM387_26130	COG1739	Uncharacterized protein family UPF0029
KM387_26135	COG1316	TRANSCRIPTIONal
KM387_26140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM387_26150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM387_26160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM387_26160	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM387_26175	COG3394	polysaccharide catabolic process
KM387_26180	COG1486	melibiose metabolic process
KM387_26185	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_26190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_26200	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM387_26205	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM387_26210	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_26220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_26225	COG1301	dicarboxylic acid transport
KM387_26235	COG0346	lactoylglutathione lyase activity
KM387_26240	COG1511	domain protein
KM387_26245	COG0583	DNA-binding transcription factor activity
KM387_26250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM387_26265	COG1271	oxidase subunit
KM387_26270	COG1294	oxidase, subunit
KM387_26275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_26295	COG2389	metal-binding protein
KM387_26305	COG1368	sulfuric ester hydrolase activity
KM387_26320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_26330	COG1215	transferase activity, transferring glycosyl groups
KM387_26335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_26340	COG3584	3D domain protein
KM387_26340	COG1388	LysM domain
KM387_26365	COG4715	Zinc finger, swim domain protein
KM387_26370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_26410	COG0577	efflux transmembrane transporter activity
KM387_26415	COG1136	(ABC) transporter
KM387_26450	COG5002	protein histidine kinase activity
KM387_26455	COG0745	RESPONSE REGULATOR receiver
KM387_26460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM387_26480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM387_26485	COG1134	teichoic acid transport
KM387_26490	COG1682	transport, permease protein
KM387_26495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM387_26540	COG1609	Transcriptional regulator
KM387_26555	COG0739	heme binding
KM387_26570	COG3279	Response regulator of the LytR AlgR family
KM387_26575	COG2385	sporulation resulting in formation of a cellular spore
KM387_26590	COG4836	Membrane
KM387_26595	COG1007	ATP synthesis coupled electron transport
KM387_26600	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM387_26605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM387_26615	COG0839	Belongs to the complex I subunit 6 family
KM387_26630	COG0649	NAD binding
KM387_26635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM387_26650	COG3300	MHYT domain
KM387_26650	COG5001	Diguanylate cyclase
KM387_26700	COG0356	it plays a direct role in the translocation of protons across the membrane
KM387_26735	COG0698	ribose 5-phosphate isomerase
KM387_26745	COG2190	(PTS) system
KM387_26750	COG2259	Doxx family
KM387_26755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM387_26770	COG0009	L-threonylcarbamoyladenylate synthase
KM387_26785	COG2890	protein-(glutamine-N5) methyltransferase activity
KM387_26805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM387_26810	COG1494	fructose-1,6-bisphosphatase
KM387_26830	COG4821	SIS domain
KM387_26850	COG1960	acyl-CoA dehydrogenase activity
KM387_26855	COG1960	acyl-CoA dehydrogenase activity
KM387_26860	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM387_26865	COG0183	Belongs to the thiolase family
KM387_26870	COG0247	lactate metabolic process
KM387_26870	COG2181	nitrate reductase activity
KM387_26875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_26885	COG5001	Diguanylate cyclase
KM387_26885	COG3300	MHYT domain
KM387_26905	COG2197	response regulator
KM387_26910	COG4585	Histidine kinase
KM387_26915	COG0842	Transport permease protein
KM387_26920	COG1131	(ABC) transporter
KM387_26925	COG0024	Methionine aminopeptidase
KM387_26935	COG2234	aminopeptidase activity
KM387_26955	COG1595	DNA-templated transcription, initiation
KM387_26965	COG4506	Protein conserved in bacteria
KM387_26970	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_26985	COG0010	Belongs to the arginase family
KM387_26995	COG2814	Major facilitator Superfamily
KM387_27000	COG0789	Transcriptional regulator
KM387_27005	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_27010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_27020	COG1994	Peptidase M50
KM387_27030	COG1078	dGTPase activity
KM387_27035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_27040	COG1120	ATPase activity
KM387_27045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_27050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_27070	COG0095	Lipoate-protein ligase
KM387_27075	COG0280	phosphate acetyltransferase
KM387_27090	COG3773	Cell wall hydrolase
KM387_27100	COG2363	Small membrane protein
KM387_27110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM387_27115	COG2233	PERMEase
KM387_27120	COG0561	phosphatase activity
KM387_27125	COG2814	Major facilitator Superfamily
KM387_27135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_27140	COG1131	(ABC) transporter
KM387_27145	COG2755	lipolytic protein G-D-S-L family
KM387_27150	COG1609	Transcriptional regulator
KM387_27160	COG0460	homoserine dehydrogenase
KM387_27170	COG2873	o-acetylhomoserine
KM387_27180	COG1011	Hydrolase
KM387_27185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM387_27195	COG2197	response regulator
KM387_27205	COG0351	phosphomethylpyrimidine kinase
KM387_27210	COG3706	GGDEF domain
KM387_27215	COG2879	small protein
KM387_27220	COG1966	Carbon starvation protein
KM387_27225	COG3279	Response regulator of the LytR AlgR family
KM387_27230	COG0477	Major facilitator Superfamily
KM387_27255	COG0840	transmembrane signaling receptor activity
KM387_27265	COG1607	acyl-coa hydrolase
KM387_27280	COG0488	(ABC) transporter
KM387_27300	COG0463	Glycosyl transferase, family 2
KM387_27305	COG1309	transcriptional regulator
KM387_27310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM387_27315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_27315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_27320	COG0628	permease
KM387_27335	COG3279	Response regulator of the LytR AlgR family
KM387_27340	COG3275	phosphorelay sensor kinase activity
KM387_27345	COG2814	Major facilitator Superfamily
KM387_27350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_27355	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM387_27360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_27380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM387_27385	COG1272	protein, Hemolysin III
KM387_27410	COG1164	Oligoendopeptidase f
KM387_27430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_27435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM387_27440	COG4853	Protein conserved in bacteria
KM387_27445	COG4863	YycH protein
KM387_27450	COG5002	protein histidine kinase activity
KM387_27455	COG0745	RESPONSE REGULATOR receiver
KM387_27485	COG0305	Participates in initiation and elongation during chromosome replication
KM387_27495	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM387_27500	COG4241	membrane
KM387_27510	COG0629	single-stranded DNA binding
KM387_27520	COG0012	GTP binding
KM387_27525	COG4481	Protein conserved in bacteria
KM387_27530	COG0668	transmembrane transport
KM387_27540	COG1475	DNA binding
KM387_27545	COG1192	Involved in chromosome partitioning
KM387_27570	COG1847	R3H domain protein
KM387_27575	COG0706	membrane insertase activity
KM387_27585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM387_27635	COG3344	reverse transcriptase
KM387_27715	COG3344	reverse transcriptase
KM387_27915	COG4962	Type ii secretion system protein e
KM387_28055	COG2311	Membrane
KM387_28075	COG4196	transglutaminase domain protein
KM387_28080	COG0671	phosphoesterase, PA-phosphatase related
KM387_28095	COG1215	transferase activity, transferring glycosyl groups
KM387_28100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM387_28105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM387_28265	COG2002	toxin-antitoxin pair type II binding
KM387_28275	COG4974	Belongs to the 'phage' integrase family
KM387_28330	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM387_28340	COG4974	Belongs to the 'phage' integrase family
KM387_28365	COG0457	Tetratricopeptide repeat
KM387_28570	COG0791	NLP P60 protein
KM387_28570	COG0741	lytic transglycosylase activity
KM387_28635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_28640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_28695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_28705	COG4166	transmembrane transport
KM387_28745	COG1280	lysine exporter protein (LysE YggA)
KM387_28770	COG0681	Belongs to the peptidase S26 family
KM387_28845	COG1309	transcriptional regulator
KM387_28850	COG1683	Conserved Protein
KM387_28895	COG1192	Involved in chromosome partitioning