locus-tag	class	description
KM410_00010	COG0592	DNA-directed DNA polymerase activity
KM410_00015	COG2501	S4 domain
KM410_00025	COG0187	DNA topoisomerase II activity
KM410_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM410_00065	COG0516	GMP reductase activity
KM410_00065	COG0517	IMP dehydrogenase activity
KM410_00070	COG1686	Belongs to the peptidase S11 family
KM410_00100	COG1428	Deoxynucleoside kinase
KM410_00105	COG1428	Deoxynucleoside kinase
KM410_00110	COG1335	isochorismatase
KM410_00115	COG0590	tRNA wobble adenosine to inosine editing
KM410_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM410_00180	COG1982	Orn Lys Arg decarboxylase major
KM410_00190	COG0470	DNA polymerase III
KM410_00195	COG1774	PSP1 C-terminal conserved region
KM410_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM410_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM410_00220	COG2002	toxin-antitoxin pair type II binding
KM410_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM410_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM410_00230	COG0084	hydrolase, TatD family'
KM410_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM410_00250	COG4466	Protein conserved in bacteria
KM410_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM410_00270	COG0251	oxidation-reduction process
KM410_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM410_00305	COG2002	toxin-antitoxin pair type II binding
KM410_00310	COG2244	polysaccharide biosynthetic process
KM410_00315	COG3956	TIGRFAM MazG family protein
KM410_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM410_00340	COG1098	S1 RNA binding domain
KM410_00355	COG2208	phosphoserine phosphatase activity
KM410_00360	COG0037	tRNA processing
KM410_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM410_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM410_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM410_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM410_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM410_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM410_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM410_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM410_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM410_00420	COG1396	sequence-specific DNA binding
KM410_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM410_00455	COG3880	PFAM UvrB UvrC protein
KM410_00465	COG0542	response to heat
KM410_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM410_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM410_00500	COG1045	serine acetyltransferase
KM410_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM410_00520	COG3688	RNA-binding protein containing a PIN domain
KM410_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM410_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM410_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM410_00565	COG2813	Specifically methylates the guanine in position
KM410_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM410_00580	COG1358	cellular component organization or biogenesis
KM410_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM410_00710	COG0201	protein transport
KM410_00720	COG0024	Methionine aminopeptidase
KM410_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM410_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM410_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM410_00795	COG0489	protein tyrosine kinase activity
KM410_00805	COG2194	sulfuric ester hydrolase activity
KM410_00810	COG0726	polysaccharide deacetylase
KM410_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM410_00895	COG4856	YbbR-like protein
KM410_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM410_00915	COG0596	Alpha beta hydrolase
KM410_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM410_00940	COG4946	Tricorn protease homolog
KM410_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM410_00940	COG1506	peptidase
KM410_00975	COG2011	ABC-type metal ion transport system permease component
KM410_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM410_00985	COG1464	Belongs to the NlpA lipoprotein family
KM410_00990	COG0604	alcohol dehydrogenase
KM410_01000	COG0277	FAD linked oxidase domain protein
KM410_01005	COG2271	Major facilitator Superfamily
KM410_01015	COG2814	Major facilitator Superfamily
KM410_01030	COG0601	transmembrane transport
KM410_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM410_01040	COG0444	Belongs to the ABC transporter superfamily
KM410_01045	COG4608	Belongs to the ABC transporter superfamily
KM410_01050	COG4166	transmembrane transport
KM410_01060	COG2207	Transcriptional regulator
KM410_01075	COG4166	transmembrane transport
KM410_01080	COG4166	transmembrane transport
KM410_01085	COG0656	L-ascorbic acid biosynthetic process
KM410_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM410_01105	COG4149	molybdate abc transporter
KM410_01115	COG1910	domain protein
KM410_01125	COG0583	DNA-binding transcription factor activity
KM410_01130	COG0697	spore germination
KM410_01145	COG0204	Acyl-transferase
KM410_01155	COG1609	Transcriptional regulator
KM410_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_01175	COG0084	hydrolase, TatD family'
KM410_01180	COG5298	Protein conserved in bacteria
KM410_01205	COG0488	(ABC) transporter
KM410_01220	COG0747	negative chemotaxis
KM410_01225	COG0601	transmembrane transport
KM410_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM410_01235	COG0444	Belongs to the ABC transporter superfamily
KM410_01240	COG4608	Belongs to the ABC transporter superfamily
KM410_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM410_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM410_01290	COG2814	Major facilitator Superfamily
KM410_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM410_01310	COG4294	response to UV
KM410_01315	COG0457	Tetratricopeptide repeat
KM410_01315	COG0705	Rhomboid family
KM410_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM410_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM410_01335	COG0864	Transcriptional regulator
KM410_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM410_01345	COG2183	response to ionizing radiation
KM410_01440	COG0802	atpase or kinase
KM410_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM410_01450	COG0456	acetyltransferase
KM410_01460	COG0488	(ABC) transporter
KM410_01475	COG1266	CAAX protease self-immunity
KM410_01495	COG2252	PERMEase
KM410_01505	COG5002	protein histidine kinase activity
KM410_01535	COG2226	methyltransferase
KM410_01575	COG1968	undecaprenyl-diphosphatase activity
KM410_01590	COG2205	protein histidine kinase activity
KM410_01595	COG0745	RESPONSE REGULATOR receiver
KM410_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM410_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM410_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM410_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM410_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM410_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM410_01670	COG0151	Belongs to the GarS family
KM410_01695	COG0210	DNA helicase
KM410_01705	COG4851	CamS sex pheromone cAM373 precursor
KM410_01725	COG1335	isochorismatase
KM410_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM410_01735	COG2011	ABC-type metal ion transport system permease component
KM410_01740	COG1464	Belongs to the NlpA lipoprotein family
KM410_01760	COG1846	Transcriptional regulator
KM410_01785	COG1597	lipid kinase activity
KM410_01790	COG0546	phosphoglycolate phosphatase activity
KM410_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM410_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM410_01810	COG2076	Multidrug Resistance protein
KM410_01815	COG2309	aminopeptidase activity
KM410_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM410_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM410_01850	COG4807	Protein conserved in bacteria
KM410_01875	COG1757	Na H antiporter
KM410_01880	COG1473	amidohydrolase
KM410_01895	COG0450	alkyl hydroperoxide reductase
KM410_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_01940	COG0166	Belongs to the GPI family
KM410_01975	COG5002	protein histidine kinase activity
KM410_01995	COG3541	Predicted nucleotidyltransferase
KM410_02000	COG2814	Major facilitator Superfamily
KM410_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM410_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM410_02015	COG0765	amino acid transport
KM410_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM410_02030	COG0840	transmembrane signaling receptor activity
KM410_02035	COG0840	transmembrane signaling receptor activity
KM410_02040	COG0366	Alpha amylase catalytic
KM410_02045	COG2190	(PTS) system
KM410_02045	COG1263	PTS System
KM410_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM410_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM410_02100	COG1116	anion transmembrane transporter activity
KM410_02105	COG0488	(ABC) transporter
KM410_02150	COG2270	Major facilitator Superfamily
KM410_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM410_02180	COG2310	stress, protein
KM410_02185	COG2310	stress, protein
KM410_02190	COG2310	stress, protein
KM410_02195	COG0861	Integral membrane protein TerC family
KM410_02205	COG3853	Toxic anion resistance protein (TelA)
KM410_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM410_02230	COG1295	ribonuclease BN
KM410_02235	COG2217	Heavy metal translocating P-type atpase
KM410_02240	COG0697	spore germination
KM410_02260	COG0586	Pfam SNARE associated Golgi protein
KM410_02275	COG3871	stress protein (general stress protein 26)
KM410_02280	COG0387	Pfam Sodium calcium exchanger
KM410_02290	COG0535	radical SAM domain protein
KM410_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM410_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM410_02325	COG0582	viral genome integration into host DNA
KM410_02335	COG1396	sequence-specific DNA binding
KM410_02350	COG1396	sequence-specific DNA binding
KM410_02385	COG1484	DNA-dependent DNA replication
KM410_02615	COG0101	tRNA pseudouridine synthase activity
KM410_02625	COG3829	transcription factor binding
KM410_02635	COG0833	amino acid
KM410_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM410_02670	COG1263	PTS System
KM410_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM410_02690	COG0463	Glycosyl transferase, family 2
KM410_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM410_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM410_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM410_02745	COG1228	amidohydrolase
KM410_02750	COG1090	epimerase
KM410_02780	COG1988	membrane-bound metal-dependent
KM410_02785	COG1194	a g-specific adenine glycosylase
KM410_02810	COG1132	(ABC) transporter
KM410_02815	COG4129	membrane
KM410_02820	COG0070	glutamate synthase
KM410_02820	COG0069	glutamate synthase activity
KM410_02820	COG0067	glutamate synthase
KM410_02830	COG4555	ABC transporter
KM410_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM410_02855	COG0735	belongs to the Fur family
KM410_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM410_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM410_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM410_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM410_03005	COG2766	serine protein kinase
KM410_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM410_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM410_03040	COG2268	Band 7 protein
KM410_03050	COG3290	protein histidine kinase activity
KM410_03055	COG4565	transcriptional regulatory protein
KM410_03060	COG2851	Citrate transporter
KM410_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM410_03085	COG3842	ATPase activity
KM410_03090	COG1175	transmembrane transport
KM410_03095	COG0395	ABC-type sugar transport system, permease component
KM410_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM410_03110	COG0745	RESPONSE REGULATOR receiver
KM410_03115	COG5002	protein histidine kinase activity
KM410_03125	COG4990	cell redox homeostasis
KM410_03135	COG3290	protein histidine kinase activity
KM410_03140	COG4565	transcriptional regulatory protein
KM410_03145	COG3493	citrate carrier protein
KM410_03150	COG0281	malic enzyme
KM410_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_03175	COG5002	protein histidine kinase activity
KM410_03180	COG0745	RESPONSE REGULATOR receiver
KM410_03185	COG0454	-acetyltransferase
KM410_03185	COG0456	acetyltransferase
KM410_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM410_03195	COG3383	formate dehydrogenase (NAD+) activity
KM410_03200	COG2427	Protein of unknown function (DUF1641)
KM410_03215	COG0531	amino acid
KM410_03220	COG0640	Transcriptional regulator
KM410_03225	COG2217	Heavy metal translocating P-type atpase
KM410_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM410_03245	COG3227	Zinc metalloprotease (Elastase)
KM410_03265	COG2720	vancomycin resistance protein
KM410_03270	COG1316	TRANSCRIPTIONal
KM410_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_03280	COG0346	lactoylglutathione lyase activity
KM410_03285	COG1253	flavin adenine dinucleotide binding
KM410_03290	COG1027	Aspartate ammonia-lyase
KM410_03295	COG1620	l-lactate permease
KM410_03310	COG3104	oligopeptide transport
KM410_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_03335	COG2226	methyltransferase
KM410_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM410_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM410_03355	COG4548	von Willebrand factor, type A
KM410_03360	COG0714	Associated with various cellular activities
KM410_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM410_03385	COG0531	amino acid
KM410_03390	COG2188	Transcriptional regulator
KM410_03395	COG1263	PTS System
KM410_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_03400	COG0366	Alpha amylase catalytic
KM410_03415	COG0697	spore germination
KM410_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM410_03430	COG1115	amino acid carrier protein
KM410_03435	COG1126	abc transporter atp-binding protein
KM410_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM410_03445	COG0765	amino acid transport
KM410_03450	COG0765	amino acid transport
KM410_03455	COG0833	amino acid
KM410_03480	COG2378	regulation of single-species biofilm formation
KM410_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM410_03490	COG5002	protein histidine kinase activity
KM410_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM410_03520	COG0747	negative chemotaxis
KM410_03530	COG0601	transmembrane transport
KM410_03535	COG4608	Belongs to the ABC transporter superfamily
KM410_03545	COG2271	Major facilitator Superfamily
KM410_03550	COG1846	Transcriptional regulator
KM410_03560	COG1609	Transcriptional regulator
KM410_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM410_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM410_03585	COG1879	ABC-type sugar transport system periplasmic component
KM410_03610	COG1063	alcohol dehydrogenase
KM410_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM410_03650	COG1968	undecaprenyl-diphosphatase activity
KM410_03655	COG0840	transmembrane signaling receptor activity
KM410_03660	COG3584	3D domain protein
KM410_03660	COG1388	LysM domain
KM410_03665	COG1476	TRANSCRIPTIONal
KM410_03680	COG3104	oligopeptide transport
KM410_03685	COG1114	Component of the transport system for branched-chain amino acids
KM410_03700	COG1113	amino acid transport
KM410_03705	COG2252	PERMEase
KM410_03730	COG0569	domain protein
KM410_03730	COG0475	glutathione-regulated potassium exporter activity
KM410_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM410_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM410_03755	COG0833	amino acid
KM410_03760	COG4990	cell redox homeostasis
KM410_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM410_03780	COG0697	spore germination
KM410_03785	COG0531	amino acid
KM410_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM410_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM410_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM410_03805	COG1918	ferrous iron import across plasma membrane
KM410_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM410_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM410_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM410_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM410_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM410_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM410_03975	COG1116	anion transmembrane transporter activity
KM410_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM410_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM410_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM410_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM410_04000	COG2104	thiamine diphosphate biosynthetic process
KM410_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM410_04015	COG0351	phosphomethylpyrimidine kinase
KM410_04055	COG2205	protein histidine kinase activity
KM410_04060	COG2814	Major facilitator Superfamily
KM410_04065	COG1846	Transcriptional regulator
KM410_04080	COG2252	PERMEase
KM410_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM410_04105	COG1621	beta-fructofuranosidase activity
KM410_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_04110	COG1263	PTS System
KM410_04115	COG1609	Transcriptional regulator
KM410_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM410_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM410_04165	COG0778	Nitroreductase
KM410_04170	COG2719	SpoVR family
KM410_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM410_04200	COG1937	Protein conserved in bacteria
KM410_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM410_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM410_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM410_04235	COG0730	response to heat
KM410_04245	COG1316	TRANSCRIPTIONal
KM410_04250	COG0604	alcohol dehydrogenase
KM410_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM410_04270	COG3711	transcriptional antiterminator
KM410_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM410_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM410_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM410_04300	COG1388	LysM domain
KM410_04300	COG3584	3D domain protein
KM410_04305	COG0577	efflux transmembrane transporter activity
KM410_04310	COG1136	(ABC) transporter
KM410_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM410_04335	COG1114	Component of the transport system for branched-chain amino acids
KM410_04340	COG3546	catalase activity
KM410_04375	COG0586	Pfam SNARE associated Golgi protein
KM410_04410	COG0531	amino acid
KM410_04415	COG0475	glutathione-regulated potassium exporter activity
KM410_04425	COG1737	Transcriptional regulator
KM410_04435	COG1263	PTS System
KM410_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_04445	COG2259	Doxx family
KM410_04460	COG0697	spore germination
KM410_04465	COG1522	sequence-specific DNA binding
KM410_04480	COG2076	Multidrug Resistance protein
KM410_04485	COG1309	transcriptional regulator
KM410_04490	COG2814	Major facilitator Superfamily
KM410_04495	COG1733	regulation of RNA biosynthetic process
KM410_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM410_04510	COG4533	DNA binding
KM410_04515	COG2211	Major facilitator Superfamily
KM410_04525	COG0693	protein deglycase activity
KM410_04530	COG0693	protein deglycase activity
KM410_04530	COG0753	catalase activity
KM410_04540	COG0531	amino acid
KM410_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM410_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM410_04560	COG1132	(ABC) transporter
KM410_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM410_04575	COG0765	amino acid transport
KM410_04580	COG1126	abc transporter atp-binding protein
KM410_04595	COG0189	ligase activity
KM410_04625	COG0028	Belongs to the TPP enzyme family
KM410_04630	COG3527	Alpha-acetolactate decarboxylase
KM410_04645	COG0561	phosphatase activity
KM410_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM410_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM410_04695	COG0653	protein targeting
KM410_04700	COG2244	polysaccharide biosynthetic process
KM410_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM410_04715	COG4196	transglutaminase domain protein
KM410_04730	COG1696	Membrane protein involved in D-alanine export
KM410_04745	COG1024	Enoyl-CoA hydratase
KM410_04765	COG1363	Peptidase, m42
KM410_04785	COG3938	Belongs to the proline racemase family
KM410_04825	COG0601	transmembrane transport
KM410_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM410_04840	COG4608	Belongs to the ABC transporter superfamily
KM410_04845	COG0322	excinuclease ABC activity
KM410_04875	COG0477	Major facilitator Superfamily
KM410_04880	COG3290	protein histidine kinase activity
KM410_04885	COG4565	transcriptional regulatory protein
KM410_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM410_04920	COG0789	Transcriptional regulator
KM410_04920	COG4978	Transcriptional regulator
KM410_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM410_04975	COG0477	Major facilitator Superfamily
KM410_05020	COG3320	Male sterility
KM410_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM410_05025	COG1309	transcriptional regulator
KM410_05045	COG1183	phosphatidylcholine synthase activity
KM410_05065	COG2376	Dihydroxyacetone kinase
KM410_05075	COG2376	Dihydroxyacetone kinase
KM410_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM410_05085	COG1959	2 iron, 2 sulfur cluster binding
KM410_05115	COG2770	Histidine kinase
KM410_05115	COG3437	response regulator, receiver
KM410_05165	COG3237	CsbD-like
KM410_05190	COG1191	sigma factor activity
KM410_05200	COG2208	phosphoserine phosphatase activity
KM410_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM410_05210	COG2198	Histidine kinase
KM410_05210	COG2205	protein histidine kinase activity
KM410_05210	COG0784	Response regulator, receiver
KM410_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM410_05265	COG0420	3'-5' exonuclease activity
KM410_05270	COG4717	serine-type aminopeptidase activity
KM410_05290	COG1309	transcriptional regulator
KM410_05295	COG2814	Major facilitator Superfamily
KM410_05300	COG0346	lactoylglutathione lyase activity
KM410_05310	COG0346	lactoylglutathione lyase activity
KM410_05315	COG0457	Tetratricopeptide repeat
KM410_05320	COG2267	carboxylic ester hydrolase activity
KM410_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM410_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM410_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM410_05395	COG0477	Major facilitator Superfamily
KM410_05400	COG0477	Major facilitator Superfamily
KM410_05410	COG3973	AAA domain
KM410_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM410_05435	COG4980	gas vesicle protein
KM410_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM410_05445	COG1131	(ABC) transporter
KM410_05450	COG4473	ABC transporter
KM410_05465	COG1309	transcriptional regulator
KM410_05475	COG3402	PFAM membrane-flanked domain
KM410_05525	COG3402	PFAM membrane-flanked domain
KM410_05530	COG3428	Bacterial PH domain
KM410_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM410_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM410_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM410_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM410_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM410_05590	COG1309	transcriptional regulator
KM410_05595	COG1511	domain protein
KM410_05620	COG1609	Transcriptional regulator
KM410_05630	COG1234	tRNA 3'-trailer cleavage
KM410_05635	COG0095	Lipoate-protein ligase
KM410_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_05675	COG3209	COG3209 Rhs family protein
KM410_05715	COG1078	dGTPase activity
KM410_05725	COG1595	DNA-templated transcription, initiation
KM410_05730	COG2207	Transcriptional regulator
KM410_05730	COG3708	Transcriptional regulator
KM410_05745	COG2205	protein histidine kinase activity
KM410_05750	COG0745	RESPONSE REGULATOR receiver
KM410_05775	COG0501	Belongs to the peptidase M48B family
KM410_05780	COG0840	transmembrane signaling receptor activity
KM410_05785	COG0697	spore germination
KM410_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM410_05810	COG2224	Isocitrate lyase
KM410_05835	COG4903	ComK protein
KM410_05840	COG0398	Pfam SNARE associated Golgi protein
KM410_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM410_05855	COG1074	ATP-dependent DNA helicase activity
KM410_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM410_05925	COG0367	asparagine synthase
KM410_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM410_05935	COG0753	catalase activity
KM410_05940	COG0004	ammonium transporteR
KM410_05960	COG2996	Protein conserved in bacteria
KM410_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM410_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_05995	COG0561	phosphatase activity
KM410_06005	COG0542	response to heat
KM410_06015	COG2267	carboxylic ester hydrolase activity
KM410_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM410_06040	COG5504	Zn-dependent protease
KM410_06050	COG0180	Tryptophanyl-tRNA synthetase
KM410_06060	COG4166	transmembrane transport
KM410_06065	COG0601	transmembrane transport
KM410_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM410_06075	COG0444	Belongs to the ABC transporter superfamily
KM410_06080	COG4608	Belongs to the ABC transporter superfamily
KM410_06085	COG0534	Mate efflux family protein
KM410_06090	COG4166	transmembrane transport
KM410_06105	COG0861	Integral membrane protein TerC family
KM410_06110	COG4862	establishment of competence for transformation
KM410_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM410_06125	COG1164	Oligoendopeptidase f
KM410_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM410_06140	COG2346	COG2346, Truncated hemoglobins
KM410_06145	COG4116	CYTH
KM410_06155	COG2357	RelA SpoT domain protein
KM410_06165	COG0564	pseudouridine synthase activity
KM410_06185	COG1216	Glycosyl transferase, family 2
KM410_06185	COG0463	Glycosyl transferase, family 2
KM410_06205	COG0457	Tetratricopeptide repeat
KM410_06205	COG0463	Glycosyl transferase, family 2
KM410_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM410_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM410_06285	COG2153	protein acetylation
KM410_06295	COG2382	esterase
KM410_06310	COG5492	domain, Protein
KM410_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM410_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM410_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM410_06360	COG1620	l-lactate permease
KM410_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM410_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM410_06430	COG1476	TRANSCRIPTIONal
KM410_06490	COG2226	methyltransferase
KM410_06500	COG1686	Belongs to the peptidase S11 family
KM410_06505	COG0681	Belongs to the peptidase S26 family
KM410_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM410_06545	COG3842	ATPase activity
KM410_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM410_06555	COG1177	transmembrane transport
KM410_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM410_06570	COG2409	Drug exporters of the RND superfamily
KM410_06580	COG0564	pseudouridine synthase activity
KM410_06590	COG2340	Cysteine-rich secretory protein family
KM410_06595	COG0247	lactate metabolic process
KM410_06600	COG0277	FAD linked oxidase domain protein
KM410_06605	COG3835	regulator
KM410_06615	COG0745	RESPONSE REGULATOR receiver
KM410_06620	COG5002	protein histidine kinase activity
KM410_06625	COG2186	Transcriptional regulator
KM410_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM410_06660	COG2116	formate transmembrane transporter activity
KM410_06665	COG0861	Integral membrane protein TerC family
KM410_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM410_06680	COG2030	dehydratase
KM410_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM410_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM410_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM410_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM410_06760	COG1349	DNA-binding transcription factor activity
KM410_06780	COG2861	carbohydrate metabolic process
KM410_06790	COG3852	Histidine kinase
KM410_06795	COG1846	Transcriptional regulator
KM410_06805	COG2318	DinB family
KM410_06810	COG5002	protein histidine kinase activity
KM410_06820	COG0720	synthase
KM410_06835	COG4873	Protein conserved in bacteria
KM410_06865	COG1780	Probably involved in ribonucleotide reductase function
KM410_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM410_06890	COG1725	Transcriptional regulator
KM410_06895	COG1131	(ABC) transporter
KM410_06905	COG1131	(ABC) transporter
KM410_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM410_06925	COG1522	sequence-specific DNA binding
KM410_06935	COG1335	isochorismatase
KM410_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM410_06950	COG2070	2-Nitropropane dioxygenase
KM410_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM410_06965	COG1696	Membrane protein involved in D-alanine export
KM410_06990	COG0716	FMN binding
KM410_07005	COG3173	Aminoglycoside phosphotransferase
KM410_07025	COG0534	Mate efflux family protein
KM410_07030	COG1968	undecaprenyl-diphosphatase activity
KM410_07045	COG1846	Transcriptional regulator
KM410_07055	COG1301	dicarboxylic acid transport
KM410_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM410_07065	COG4709	membrane
KM410_07070	COG3874	Sporulation protein YtfJ
KM410_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM410_07100	COG0028	Belongs to the TPP enzyme family
KM410_07105	COG0440	acetolactate synthase activity
KM410_07110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM410_07120	COG0473	3-isopropylmalate dehydrogenase activity
KM410_07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM410_07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM410_07195	COG1183	phosphatidylcholine synthase activity
KM410_07200	COG1368	sulfuric ester hydrolase activity
KM410_07210	COG0019	diaminopimelate decarboxylase activity
KM410_07230	COG0529	Catalyzes the synthesis of activated sulfate
KM410_07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM410_07255	COG1648	precorrin-2 dehydrogenase activity
KM410_07260	COG0733	neurotransmitter:sodium symporter activity
KM410_07280	COG1757	Na H antiporter
KM410_07295	COG4758	membrane
KM410_07300	COG4585	Histidine kinase
KM410_07305	COG2197	response regulator
KM410_07315	COG1114	Component of the transport system for branched-chain amino acids
KM410_07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM410_07350	COG1017	nitric oxide dioxygenase activity
KM410_07350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM410_07365	COG0730	response to heat
KM410_07370	COG0306	phosphate transporter
KM410_07375	COG1392	Phosphate transport regulator
KM410_07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM410_07395	COG3852	Histidine kinase
KM410_07400	COG1801	Protein of unknown function DUF72
KM410_07410	COG0582	viral genome integration into host DNA
KM410_07415	COG5002	protein histidine kinase activity
KM410_07435	COG0392	lysyltransferase activity
KM410_07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM410_07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM410_07455	COG1686	Belongs to the peptidase S11 family
KM410_07460	COG2715	membrane protein required for spore maturation
KM410_07465	COG0700	Nucleoside recognition
KM410_07470	COG1187	pseudouridine synthase activity
KM410_07480	COG1333	cytochrome c biogenesis protein
KM410_07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM410_07490	COG0745	RESPONSE REGULATOR receiver
KM410_07495	COG5002	protein histidine kinase activity
KM410_07500	COG2096	Adenosyltransferase
KM410_07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM410_07520	COG1141	Ferredoxin
KM410_07525	COG4955	Helix-turn-helix domain
KM410_07530	COG0514	ATP-dependent DNA helicase (RecQ)
KM410_07535	COG1266	CAAX protease self-immunity
KM410_07555	COG4862	establishment of competence for transformation
KM410_07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM410_07580	COG0492	ferredoxin-NADP+ reductase activity
KM410_07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM410_07670	COG0142	geranyltranstransferase activity
KM410_07680	COG0142	geranyltranstransferase activity
KM410_07700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM410_07705	COG0457	Tetratricopeptide repeat
KM410_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM410_07735	COG4347	Protein of unknown function (DUF1405)
KM410_07750	COG2738	Putative neutral zinc metallopeptidase
KM410_07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_07765	COG1694	Mazg nucleotide pyrophosphohydrolase
KM410_07780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM410_07785	COG0438	transferase activity, transferring glycosyl groups
KM410_07820	COG1199	ATP-dependent helicase activity
KM410_07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM410_07840	COG3935	DnaD domain protein
KM410_07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM410_07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM410_07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM410_07915	COG0116	Belongs to the methyltransferase superfamily
KM410_07925	COG1199	ATP-dependent helicase activity
KM410_07930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM410_07940	COG3173	Aminoglycoside phosphotransferase
KM410_07945	COG0024	Methionine aminopeptidase
KM410_07955	COG2233	PERMEase
KM410_07960	COG2311	Membrane
KM410_07965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM410_07975	COG0456	acetyltransferase
KM410_08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM410_08050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM410_08065	COG1215	transferase activity, transferring glycosyl groups
KM410_08070	COG0438	transferase activity, transferring glycosyl groups
KM410_08085	COG0454	-acetyltransferase
KM410_08105	COG0328	RNA-DNA hybrid ribonuclease activity
KM410_08145	COG1280	lysine exporter protein (LysE YggA)
KM410_08160	COG3162	membrane
KM410_08165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM410_08170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM410_08180	COG0475	glutathione-regulated potassium exporter activity
KM410_08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM410_08190	COG0789	Transcriptional regulator
KM410_08190	COG4978	Transcriptional regulator
KM410_08200	COG2323	membrane
KM410_08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM410_08260	COG1923	regulation of RNA biosynthetic process
KM410_08270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM410_08275	COG1360	Flagellar Motor Protein
KM410_08280	COG2201	protein-glutamate methylesterase activity
KM410_08285	COG0643	Histidine kinase
KM410_08285	COG2198	Histidine kinase
KM410_08290	COG2198	Histidine kinase
KM410_08290	COG0643	Histidine kinase
KM410_08295	COG1776	CheC inhibitor of MCP methylation
KM410_08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM410_08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM410_08330	COG1256	bacterial-type flagellum assembly
KM410_08355	COG1815	bacterial-type flagellum-dependent cell motility
KM410_08360	COG1558	bacterial-type flagellum-dependent cell motility
KM410_08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM410_08385	COG1157	protein secretion by the type III secretion system
KM410_08425	COG0835	chemotaxis
KM410_08425	COG0784	Response regulator, receiver
KM410_08435	COG0463	Glycosyl transferase, family 2
KM410_08475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM410_08480	COG0741	lytic transglycosylase activity
KM410_08495	COG1776	CheC inhibitor of MCP methylation
KM410_08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM410_08505	COG1338	Plays a role in the flagellum-specific transport system
KM410_08510	COG1987	bacterial-type flagellum assembly
KM410_08520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM410_08525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM410_08530	COG1419	protein localization to endoplasmic reticulum
KM410_08535	COG4786	Flagellar basal body rod
KM410_08540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM410_08565	COG1309	transcriptional regulator
KM410_08585	COG2329	Antibiotic biosynthesis monooxygenase
KM410_08610	COG0583	DNA-binding transcription factor activity
KM410_08615	COG3842	ATPase activity
KM410_08620	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM410_08630	COG1234	tRNA 3'-trailer cleavage
KM410_08655	COG1686	Belongs to the peptidase S11 family
KM410_08665	COG0406	alpha-ribazole phosphatase activity
KM410_08695	COG0367	asparagine synthase
KM410_08725	COG1802	Transcriptional regulator
KM410_08730	COG0697	spore germination
KM410_08735	COG0523	cobalamin synthesis protein
KM410_08740	COG0701	Predicted permease
KM410_08750	COG1216	Glycosyl transferase, family 2
KM410_08750	COG0438	transferase activity, transferring glycosyl groups
KM410_08755	COG1757	Na H antiporter
KM410_08760	COG0114	fumarate hydratase activity
KM410_08785	COG3340	Belongs to the peptidase S51 family
KM410_08805	COG0785	Cytochrome C biogenesis protein
KM410_08835	COG2733	membrane
KM410_08870	COG1131	(ABC) transporter
KM410_08885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM410_08890	COG0528	UMP kinase activity
KM410_08900	COG1027	Aspartate ammonia-lyase
KM410_08905	COG0281	malic enzyme
KM410_08910	COG4191	Histidine kinase
KM410_08915	COG0784	Response regulator, receiver
KM410_08920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM410_08975	COG1051	belongs to the nudix hydrolase family
KM410_08980	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM410_08990	COG2814	Major facilitator Superfamily
KM410_09005	COG1966	Carbon starvation protein
KM410_09020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_09030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM410_09040	COG2223	nitrite transmembrane transporter activity
KM410_09045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM410_09060	COG2244	polysaccharide biosynthetic process
KM410_09065	COG0733	neurotransmitter:sodium symporter activity
KM410_09075	COG5566	PFAM Mor transcription activator
KM410_09080	COG2323	membrane
KM410_09095	COG2084	Dehydrogenase
KM410_09110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM410_09120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM410_09125	COG0028	Belongs to the TPP enzyme family
KM410_09130	COG0440	acetolactate synthase activity
KM410_09135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM410_09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM410_09170	COG2814	Major facilitator Superfamily
KM410_09175	COG3384	dioxygenase
KM410_09185	COG3279	Response regulator of the LytR AlgR family
KM410_09190	COG0427	acetyl-CoA hydrolase
KM410_09210	COG1073	alpha beta
KM410_09240	COG0535	radical SAM domain protein
KM410_09245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_09265	COG1914	H( )-stimulated, divalent metal cation uptake system
KM410_09280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM410_09310	COG2390	Transcriptional regulator
KM410_09320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_09325	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM410_09340	COG4224	UPF0291 protein
KM410_09360	COG0006	proline dipeptidase activity
KM410_09365	COG2132	Multicopper oxidase
KM410_09380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM410_09395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM410_09410	COG1276	copper resistance
KM410_09410	COG2372	response to copper ion
KM410_09415	COG4549	nuclear export factor GLE1
KM410_09425	COG0697	spore germination
KM410_09430	COG0583	DNA-binding transcription factor activity
KM410_09435	COG1959	2 iron, 2 sulfur cluster binding
KM410_09440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM410_09445	COG0778	Nitroreductase
KM410_09455	COG0628	permease
KM410_09465	COG1231	oxidoreductase activity
KM410_09470	COG0523	cobalamin synthesis protein
KM410_09485	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_09490	COG2030	dehydratase
KM410_09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_09505	COG0411	ABC transporter
KM410_09525	COG0583	DNA-binding transcription factor activity
KM410_09535	COG1942	4-Oxalocrotonate Tautomerase
KM410_09545	COG1846	Transcriptional regulator
KM410_09555	COG1271	oxidase subunit
KM410_09560	COG1294	oxidase, subunit
KM410_09565	COG4988	ABC transporter
KM410_09570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM410_09590	COG1686	Belongs to the peptidase S11 family
KM410_09605	COG0791	NLP P60 protein
KM410_09605	COG1388	LysM domain
KM410_09620	COG0745	RESPONSE REGULATOR receiver
KM410_09625	COG5002	protein histidine kinase activity
KM410_09635	COG0300	oxidoreductase activity
KM410_09670	COG0460	homoserine dehydrogenase
KM410_09695	COG1316	TRANSCRIPTIONal
KM410_09705	COG0745	RESPONSE REGULATOR receiver
KM410_09710	COG5002	protein histidine kinase activity
KM410_09725	COG1285	pathogenesis
KM410_09730	COG1247	-acetyltransferase
KM410_09750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM410_09760	COG1082	Xylose isomerase domain protein TIM barrel
KM410_09775	COG1279	arginine transmembrane transporter activity
KM410_09785	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM410_09825	COG2002	toxin-antitoxin pair type II binding
KM410_09830	COG1404	Belongs to the peptidase S8 family
KM410_09835	COG0640	Transcriptional regulator
KM410_09840	COG0667	Aldo Keto reductase
KM410_09845	COG2814	Major facilitator Superfamily
KM410_09870	COG0840	transmembrane signaling receptor activity
KM410_09885	COG3949	Membrane
KM410_09890	COG0783	Belongs to the Dps family
KM410_09905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM410_09915	COG1231	oxidoreductase activity
KM410_09925	COG4989	oxidoreductase activity
KM410_09930	COG0523	cobalamin synthesis protein
KM410_09935	COG0456	acetyltransferase
KM410_09990	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM410_09990	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM410_10000	COG0702	epimerase
KM410_10010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM410_10020	COG4166	transmembrane transport
KM410_10035	COG0406	alpha-ribazole phosphatase activity
KM410_10045	COG5337	Spore coat protein CotH
KM410_10050	COG1051	belongs to the nudix hydrolase family
KM410_10055	COG0586	Pfam SNARE associated Golgi protein
KM410_10060	COG2244	polysaccharide biosynthetic process
KM410_10070	COG0701	Predicted permease
KM410_10075	COG3689	TIGRFAM TIGR03943 family protein
KM410_10080	COG1607	acyl-coa hydrolase
KM410_10090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM410_10105	COG0702	epimerase
KM410_10110	COG2839	Protein conserved in bacteria
KM410_10115	COG1253	flavin adenine dinucleotide binding
KM410_10130	COG1114	Component of the transport system for branched-chain amino acids
KM410_10135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM410_10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM410_10165	COG1876	peptidase activity
KM410_10175	COG0154	amidase activity
KM410_10180	COG2211	Major facilitator Superfamily
KM410_10200	COG0561	phosphatase activity
KM410_10210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM410_10215	COG4106	trans-aconitate 2-methyltransferase activity
KM410_10230	COG1819	glycosyl
KM410_10235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_10240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_10265	COG0456	acetyltransferase
KM410_10315	COG3874	Sporulation protein YtfJ
KM410_10340	COG2226	methyltransferase
KM410_10365	COG0346	lactoylglutathione lyase activity
KM410_10375	COG0604	alcohol dehydrogenase
KM410_10380	COG1595	DNA-templated transcription, initiation
KM410_10405	COG0386	Belongs to the glutathione peroxidase family
KM410_10410	COG1305	Transglutaminase-like
KM410_10415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM410_10420	COG0714	Associated with various cellular activities
KM410_10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM410_10440	COG1140	nitrate reductase beta subunit
KM410_10445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM410_10450	COG2181	nitrate reductase activity
KM410_10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM410_10475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM410_10480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM410_10485	COG0303	'Molybdopterin
KM410_10490	COG0314	molybdopterin synthase activity
KM410_10500	COG2223	nitrite transmembrane transporter activity
KM410_10515	COG1648	precorrin-2 dehydrogenase activity
KM410_10525	COG1587	Uroporphyrinogen-III synthase
KM410_10525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM410_10530	COG2146	nitrite reductase [NAD(P)H] activity
KM410_10535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM410_10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM410_10575	COG2359	stage V sporulation protein S
KM410_10590	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM410_10605	COG1418	mRNA catabolic process
KM410_10610	COG0488	(ABC) transporter
KM410_10625	COG0629	single-stranded DNA binding
KM410_10640	COG1413	lyase activity
KM410_10655	COG2136	Putative SAM-dependent methyltransferase
KM410_10655	COG2521	methyltransferase
KM410_10660	COG0018	arginyl-trna synthetase
KM410_10685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM410_10705	COG0017	Asparaginyl-tRNA synthetase
KM410_10725	COG1674	ftsk spoiiie
KM410_10795	COG1929	Belongs to the glycerate kinase type-1 family
KM410_10800	COG0471	metal ion transport
KM410_10805	COG0745	RESPONSE REGULATOR receiver
KM410_10810	COG3850	Histidine kinase
KM410_10810	COG5002	protein histidine kinase activity
KM410_10825	COG0733	neurotransmitter:sodium symporter activity
KM410_10850	COG2610	gluconate transmembrane transporter activity
KM410_10855	COG1454	alcohol dehydrogenase
KM410_10860	COG1794	racemase activity, acting on amino acids and derivatives
KM410_10870	COG0456	acetyltransferase
KM410_10885	COG1131	(ABC) transporter
KM410_10900	COG0546	phosphoglycolate phosphatase activity
KM410_10920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM410_10935	COG0768	penicillin binding
KM410_10940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM410_10945	COG0204	Acyl-transferase
KM410_10950	COG1272	protein, Hemolysin III
KM410_10960	COG0805	protein transport
KM410_10970	COG1307	EDD domain protein, DegV family
KM410_10975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM410_10980	COG1999	signal sequence binding
KM410_10985	COG0071	Belongs to the small heat shock protein (HSP20) family
KM410_10990	COG0367	asparagine synthase
KM410_11005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_11010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM410_11035	COG1051	belongs to the nudix hydrolase family
KM410_11045	COG0668	transmembrane transport
KM410_11050	COG2203	Gaf domain
KM410_11050	COG4585	Histidine kinase
KM410_11055	COG2197	response regulator
KM410_11065	COG1064	alcohol dehydrogenase
KM410_11090	COG1070	Carbohydrate kinase
KM410_11095	COG1070	Carbohydrate kinase
KM410_11125	COG0517	IMP dehydrogenase activity
KM410_11125	COG1125	glycine betaine transport
KM410_11130	COG1174	glycine betaine transport
KM410_11165	COG1253	flavin adenine dinucleotide binding
KM410_11170	COG1012	belongs to the aldehyde dehydrogenase family
KM410_11175	COG5506	Protein of unknown function (DUF1694)
KM410_11190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM410_11195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM410_11200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM410_11205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM410_11210	COG0456	acetyltransferase
KM410_11215	COG3829	transcription factor binding
KM410_11220	COG1509	lysine 2,3-aminomutase activity
KM410_11260	COG4326	sporulation control protein
KM410_11265	COG0671	phosphoesterase, PA-phosphatase related
KM410_11270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM410_11275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM410_11305	COG1787	Restriction endonuclease
KM410_11305	COG1715	Restriction endonuclease
KM410_11395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM410_11435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM410_11435	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM410_11440	COG2814	Major facilitator Superfamily
KM410_11445	COG4841	protein insertion into membrane
KM410_11450	COG0372	Belongs to the citrate synthase family
KM410_11455	COG2079	MmgE PrpD family protein
KM410_11460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM410_11465	COG1960	acyl-CoA dehydrogenase activity
KM410_11470	COG2084	Dehydrogenase
KM410_11480	COG1280	lysine exporter protein (LysE YggA)
KM410_11485	COG1024	Enoyl-CoA hydratase
KM410_11500	COG0420	3'-5' exonuclease activity
KM410_11505	COG0419	ATPase involved in DNA repair
KM410_11530	COG2223	nitrite transmembrane transporter activity
KM410_11535	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_11540	COG1169	isochorismate synthase
KM410_11545	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM410_11550	COG3433	isochorismatase activity
KM410_11550	COG1535	isochorismatase
KM410_11555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM410_11560	COG3251	PFAM MbtH domain protein
KM410_11565	COG2814	Major facilitator Superfamily
KM410_11580	COG0776	regulation of translation
KM410_11590	COG2318	DinB family
KM410_11600	COG1115	amino acid carrier protein
KM410_11615	COG2329	Antibiotic biosynthesis monooxygenase
KM410_11620	COG1187	pseudouridine synthase activity
KM410_11625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM410_11640	COG0596	Alpha beta hydrolase
KM410_11645	COG2814	Major facilitator Superfamily
KM410_11665	COG2226	methyltransferase
KM410_11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_11745	COG1247	-acetyltransferase
KM410_11775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM410_11785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_11795	COG1278	Cold shock
KM410_11810	COG0010	Belongs to the arginase family
KM410_11815	COG0561	phosphatase activity
KM410_11860	COG0583	DNA-binding transcription factor activity
KM410_11865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM410_11880	COG0583	DNA-binding transcription factor activity
KM410_11885	COG2258	MOSC domain
KM410_11900	COG1132	(ABC) transporter
KM410_11905	COG1132	(ABC) transporter
KM410_11925	COG1396	sequence-specific DNA binding
KM410_11950	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM410_11955	COG1595	DNA-templated transcription, initiation
KM410_11980	COG1649	PFAM Uncharacterised BCR, COG1649
KM410_12005	COG2971	BadF BadG BcrA BcrD
KM410_12010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM410_12015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM410_12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_12065	COG1309	transcriptional regulator
KM410_12080	COG0577	efflux transmembrane transporter activity
KM410_12080	COG1136	(ABC) transporter
KM410_12085	COG0500	methyltransferase
KM410_12085	COG3615	Tellurite resistance protein tehB
KM410_12095	COG2226	methyltransferase
KM410_12100	COG3961	Belongs to the TPP enzyme family
KM410_12105	COG1846	Transcriptional regulator
KM410_12145	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM410_12160	COG1595	DNA-templated transcription, initiation
KM410_12170	COG0768	penicillin binding
KM410_12180	COG2367	Beta-lactamase
KM410_12185	COG0671	phosphoesterase, PA-phosphatase related
KM410_12190	COG1609	Transcriptional regulator
KM410_12195	COG2814	Major facilitator Superfamily
KM410_12200	COG0673	inositol 2-dehydrogenase activity
KM410_12210	COG1012	belongs to the aldehyde dehydrogenase family
KM410_12225	COG0191	fructose-bisphosphate aldolase activity
KM410_12230	COG3718	enzyme involved in inositol metabolism
KM410_12255	COG0457	Tetratricopeptide repeat
KM410_12260	COG1476	TRANSCRIPTIONal
KM410_12275	COG1876	peptidase activity
KM410_12295	COG1309	transcriptional regulator
KM410_12300	COG0488	(ABC) transporter
KM410_12315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_12330	COG1252	NADH dehydrogenase
KM410_12335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_12350	COG1131	(ABC) transporter
KM410_12360	COG1309	transcriptional regulator
KM410_12375	COG1960	acyl-CoA dehydrogenase activity
KM410_12380	COG0439	Biotin carboxylase
KM410_12385	COG0511	ligase activity, forming carbon-carbon bonds
KM410_12390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM410_12395	COG1024	Enoyl-CoA hydratase
KM410_12400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM410_12405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM410_12415	COG1247	-acetyltransferase
KM410_12420	COG0572	uridine kinase
KM410_12430	COG2318	DinB family
KM410_12435	COG1686	Belongs to the peptidase S11 family
KM410_12460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM410_12500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM410_12500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM410_12525	COG2814	Major facilitator Superfamily
KM410_12545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM410_12565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_12580	COG1063	alcohol dehydrogenase
KM410_12610	COG3773	Cell wall hydrolase
KM410_12620	COG0745	RESPONSE REGULATOR receiver
KM410_12635	COG0488	(ABC) transporter
KM410_12650	COG1136	(ABC) transporter
KM410_12675	COG0460	homoserine dehydrogenase
KM410_12680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_12690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM410_12755	COG2124	cytochrome p450
KM410_12790	COG0561	phosphatase activity
KM410_12800	COG5002	protein histidine kinase activity
KM410_12805	COG0768	penicillin binding
KM410_12810	COG1819	glycosyl
KM410_12815	COG1794	racemase activity, acting on amino acids and derivatives
KM410_12825	COG1122	ATPase activity
KM410_12840	COG2205	protein histidine kinase activity
KM410_12850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM410_12855	COG0604	alcohol dehydrogenase
KM410_12860	COG0768	penicillin binding
KM410_12870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM410_12905	COG0693	protein deglycase activity
KM410_12935	COG2814	Major facilitator Superfamily
KM410_12950	COG0584	glycerophosphoryl diester phosphodiesterase
KM410_12970	COG0697	spore germination
KM410_12995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM410_13005	COG2223	nitrite transmembrane transporter activity
KM410_13020	COG2816	NAD+ diphosphatase activity
KM410_13025	COG0592	DNA-directed DNA polymerase activity
KM410_13030	COG1051	belongs to the nudix hydrolase family
KM410_13065	COG3878	Protein conserved in bacteria
KM410_13110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM410_13125	COG0322	excinuclease ABC activity
KM410_13165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM410_13190	COG1011	Hydrolase
KM410_13210	COG0076	glutamate decarboxylase activity
KM410_13225	COG1523	belongs to the glycosyl hydrolase 13 family
KM410_13230	COG3227	Zinc metalloprotease (Elastase)
KM410_13250	COG0201	protein transport
KM410_13260	COG0697	spore germination
KM410_13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_13295	COG4129	membrane
KM410_13300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_13315	COG2959	enzyme of heme biosynthesis
KM410_13335	COG3483	tryptophan 2,3-dioxygenase activity
KM410_13340	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM410_13345	COG3844	kynureninase activity
KM410_13350	COG1309	transcriptional regulator
KM410_13380	COG3284	Transcriptional regulator
KM410_13400	COG1349	DNA-binding transcription factor activity
KM410_13420	COG1959	2 iron, 2 sulfur cluster binding
KM410_13435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM410_13440	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM410_13445	COG0022	dehydrogenase e1 component
KM410_13450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM410_13460	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_13465	COG0456	acetyltransferase
KM410_13465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM410_13495	COG4176	ABC-type proline glycine betaine transport system permease component
KM410_13500	COG0517	IMP dehydrogenase activity
KM410_13500	COG4175	Glycine betaine
KM410_13525	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM410_13530	COG2153	protein acetylation
KM410_13535	COG3397	chitin binding
KM410_13550	COG2205	protein histidine kinase activity
KM410_13575	COG0658	competence protein
KM410_13575	COG2333	competence protein COMEC
KM410_13625	COG3973	AAA domain
KM410_13640	COG2105	PFAM AIG2 family protein
KM410_13645	COG0514	ATP-dependent DNA helicase (RecQ)
KM410_13665	COG4637	Psort location Cytoplasmic, score
KM410_13690	COG3397	chitin binding
KM410_13705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM410_13710	COG1115	amino acid carrier protein
KM410_13715	COG1012	belongs to the aldehyde dehydrogenase family
KM410_13720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM410_13730	COG3938	Belongs to the proline racemase family
KM410_13735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM410_13775	COG0586	Pfam SNARE associated Golgi protein
KM410_13790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM410_13795	COG0519	Catalyzes the synthesis of GMP from XMP
KM410_13800	COG4166	transmembrane transport
KM410_13810	COG4948	Mandelate Racemase Muconate Lactonizing
KM410_13855	COG2936	dipeptidyl-peptidase activity
KM410_13860	COG5002	protein histidine kinase activity
KM410_13900	COG1164	Oligoendopeptidase f
KM410_13915	COG1307	EDD domain protein, DegV family
KM410_13935	COG2814	Major facilitator Superfamily
KM410_13945	COG1664	Polymer-forming cytoskeletal
KM410_13950	COG0789	Transcriptional regulator
KM410_13955	COG4533	DNA binding
KM410_13960	COG0477	Major facilitator Superfamily
KM410_13960	COG2814	Major facilitator Superfamily
KM410_13980	COG2261	transglycosylase associated protein
KM410_13995	COG2226	methyltransferase
KM410_14030	COG0436	Aminotransferase
KM410_14035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM410_14040	COG5146	pantothenate kinase activity
KM410_14060	COG1131	(ABC) transporter
KM410_14105	COG0628	permease
KM410_14115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM410_14120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM410_14125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM410_14130	COG1116	anion transmembrane transporter activity
KM410_14150	COG2816	NAD+ diphosphatase activity
KM410_14170	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM410_14195	COG0697	spore germination
KM410_14200	COG2318	DinB family
KM410_14220	COG4912	Dna alkylation repair
KM410_14240	COG0861	Integral membrane protein TerC family
KM410_14245	COG1368	sulfuric ester hydrolase activity
KM410_14250	COG0488	(ABC) transporter
KM410_14260	COG1033	growth of symbiont in host cell
KM410_14260	COG2409	Drug exporters of the RND superfamily
KM410_14265	COG1033	growth of symbiont in host cell
KM410_14265	COG2409	Drug exporters of the RND superfamily
KM410_14270	COG2409	Drug exporters of the RND superfamily
KM410_14270	COG1033	growth of symbiont in host cell
KM410_14275	COG1309	transcriptional regulator
KM410_14290	COG0287	Prephenate dehydrogenase
KM410_14295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM410_14300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM410_14305	COG1605	Chorismate mutase
KM410_14305	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM410_14340	COG1388	LysM domain
KM410_14340	COG3584	3D domain protein
KM410_14350	COG1595	DNA-templated transcription, initiation
KM410_14375	COG1879	ABC-type sugar transport system periplasmic component
KM410_14385	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM410_14395	COG2390	Transcriptional regulator
KM410_14430	COG2329	Antibiotic biosynthesis monooxygenase
KM410_14450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_14460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM410_14465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM410_14470	COG4187	Peptidase family M20/M25/M40
KM410_14475	COG1414	Transcriptional regulator
KM410_14480	COG0833	amino acid
KM410_14485	COG1690	Belongs to the RtcB family
KM410_14490	COG3239	Fatty acid desaturase
KM410_14495	COG1785	Belongs to the alkaline phosphatase family
KM410_14505	COG3655	Transcriptional regulator
KM410_14520	COG4377	Putative membrane peptidase family (DUF2324)
KM410_14530	COG3279	Response regulator of the LytR AlgR family
KM410_14540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_14545	COG0346	lactoylglutathione lyase activity
KM410_14565	COG0714	Associated with various cellular activities
KM410_14590	COG0463	Glycosyl transferase, family 2
KM410_14615	COG0463	Glycosyl transferase, family 2
KM410_14625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM410_14630	COG0753	catalase activity
KM410_14640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM410_14665	COG0714	Associated with various cellular activities
KM410_14675	COG0778	Nitroreductase
KM410_14680	COG1846	Transcriptional regulator
KM410_14715	COG1725	Transcriptional regulator
KM410_14725	COG0577	efflux transmembrane transporter activity
KM410_14725	COG1136	(ABC) transporter
KM410_14750	COG2207	Transcriptional regulator
KM410_14755	COG0456	acetyltransferase
KM410_14775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_14795	COG0642	Histidine kinase
KM410_14800	COG0745	RESPONSE REGULATOR receiver
KM410_14805	COG0596	Alpha beta hydrolase
KM410_14835	COG0730	response to heat
KM410_14845	COG0833	amino acid
KM410_14855	COG4335	DNA alkylation repair
KM410_14895	COG0768	penicillin binding
KM410_14905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM410_14935	COG1984	allophanate hydrolase subunit 2
KM410_14940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM410_14945	COG1414	Transcriptional regulator
KM410_14960	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM410_14965	COG0640	Transcriptional regulator
KM410_14975	COG1960	acyl-CoA dehydrogenase activity
KM410_14990	COG3314	Sporulation integral membrane protein YlbJ
KM410_15005	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM410_15020	COG0574	Belongs to the PEP-utilizing enzyme family
KM410_15020	COG3848	Pyruvate phosphate dikinase
KM410_15025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_15040	COG5577	PFAM Coat F domain
KM410_15045	COG3403	YqcI/YcgG family
KM410_15050	COG1280	lysine exporter protein (LysE YggA)
KM410_15085	COG1063	alcohol dehydrogenase
KM410_15100	COG1027	Aspartate ammonia-lyase
KM410_15105	COG0252	asparaginase activity
KM410_15110	COG1396	sequence-specific DNA binding
KM410_15120	COG0322	excinuclease ABC activity
KM410_15125	COG0531	amino acid
KM410_15130	COG1114	Component of the transport system for branched-chain amino acids
KM410_15135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM410_15145	COG0281	malic enzyme
KM410_15160	COG0531	amino acid
KM410_15170	COG0784	Response regulator, receiver
KM410_15180	COG2066	Belongs to the glutaminase family
KM410_15185	COG1115	amino acid carrier protein
KM410_15215	COG0737	Belongs to the 5'-nucleotidase family
KM410_15220	COG0753	catalase activity
KM410_15225	COG2267	carboxylic ester hydrolase activity
KM410_15230	COG1335	isochorismatase
KM410_15250	COG0583	DNA-binding transcription factor activity
KM410_15255	COG1846	Transcriptional regulator
KM410_15295	COG0415	Belongs to the DNA photolyase family
KM410_15300	COG0288	reversible hydration of carbon dioxide
KM410_15310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM410_15315	COG5609	conserved protein (DUF2294)
KM410_15330	COG1575	Belongs to the MenA family. Type 1 subfamily
KM410_15335	COG2267	carboxylic ester hydrolase activity
KM410_15340	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM410_15345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM410_15350	COG1121	(ABC) transporter
KM410_15380	COG0798	PFAM Bile acid sodium symporter
KM410_15385	COG0346	lactoylglutathione lyase activity
KM410_15390	COG0640	Transcriptional regulator
KM410_15405	COG0443	Heat shock 70 kDa protein
KM410_15420	COG1522	sequence-specific DNA binding
KM410_15435	COG0346	lactoylglutathione lyase activity
KM410_15460	COG2169	Transcriptional regulator
KM410_15505	COG2814	Major facilitator Superfamily
KM410_15530	COG0745	RESPONSE REGULATOR receiver
KM410_15535	COG3850	Histidine kinase
KM410_15535	COG5002	protein histidine kinase activity
KM410_15560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM410_15580	COG1476	TRANSCRIPTIONal
KM410_15595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM410_15610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_15615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM410_15630	COG1136	(ABC) transporter
KM410_15635	COG0577	efflux transmembrane transporter activity
KM410_15650	COG5002	protein histidine kinase activity
KM410_15650	COG3850	Histidine kinase
KM410_15660	COG2364	Membrane
KM410_15665	COG1846	Transcriptional regulator
KM410_15675	COG2808	Putative FMN-binding domain
KM410_15680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_15685	COG2271	Major facilitator Superfamily
KM410_15690	COG1556	Lactate utilization protein
KM410_15695	COG1139	Iron-sulfur cluster binding protein
KM410_15705	COG0583	DNA-binding transcription factor activity
KM410_15715	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM410_15740	COG0738	Major facilitator superfamily
KM410_15745	COG0673	inositol 2-dehydrogenase activity
KM410_15750	COG0561	phosphatase activity
KM410_15760	COG1609	Transcriptional regulator
KM410_15765	COG0457	Tetratricopeptide repeat
KM410_15785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM410_15815	COG0534	Mate efflux family protein
KM410_15835	COG2814	Major facilitator Superfamily
KM410_15840	COG1309	transcriptional regulator
KM410_15855	COG0814	amino acid
KM410_15860	COG1760	l-serine dehydratase
KM410_15865	COG1760	l-serine dehydratase
KM410_15875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM410_15880	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM410_15890	COG1335	isochorismatase
KM410_15895	COG1522	sequence-specific DNA binding
KM410_15900	COG0531	amino acid
KM410_15915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM410_15935	COG1595	DNA-templated transcription, initiation
KM410_15950	COG0662	Cupin 2, conserved barrel domain protein
KM410_15955	COG2207	Transcriptional regulator
KM410_15955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_16005	COG0477	Major facilitator Superfamily
KM410_16015	COG1846	Transcriptional regulator
KM410_16020	COG2814	Major facilitator Superfamily
KM410_16030	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM410_16035	COG1131	(ABC) transporter
KM410_16055	COG2076	Multidrug Resistance protein
KM410_16060	COG1309	transcriptional regulator
KM410_16070	COG2031	fatty acid transporter
KM410_16080	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM410_16110	COG1122	ATPase activity
KM410_16115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM410_16130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM410_16135	COG1288	antiporter activity
KM410_16140	COG2356	endonuclease I
KM410_16155	COG3620	sequence-specific DNA binding
KM410_16160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM410_16165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM410_16170	COG0124	histidyl-tRNA synthetase
KM410_16185	COG1733	regulation of RNA biosynthetic process
KM410_16190	COG0778	Nitroreductase
KM410_16210	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_16220	COG1131	(ABC) transporter
KM410_16245	COG1011	Hydrolase
KM410_16255	COG2365	Tyrosine phosphatase family
KM410_16280	COG0346	lactoylglutathione lyase activity
KM410_16285	COG1940	carbohydrate kinase activity
KM410_16290	COG0738	Major facilitator superfamily
KM410_16295	COG0110	maltose O-acetyltransferase activity
KM410_16305	COG0577	efflux transmembrane transporter activity
KM410_16305	COG1136	(ABC) transporter
KM410_16325	COG0628	permease
KM410_16345	COG2226	methyltransferase
KM410_16355	COG0477	Major facilitator Superfamily
KM410_16385	COG1253	flavin adenine dinucleotide binding
KM410_16390	COG0789	Transcriptional regulator
KM410_16395	COG0697	spore germination
KM410_16400	COG1357	PFAM Pentapeptide repeats (8 copies)
KM410_16405	COG3813	Protein conserved in bacteria
KM410_16410	COG2706	6-phosphogluconolactonase activity
KM410_16415	COG1070	Carbohydrate kinase
KM410_16425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM410_16430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM410_16440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM410_16445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM410_16450	COG0604	alcohol dehydrogenase
KM410_16455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM410_16465	COG0604	alcohol dehydrogenase
KM410_16465	COG3321	synthase
KM410_16470	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_16495	COG0656	L-ascorbic acid biosynthetic process
KM410_16500	COG2814	Major facilitator Superfamily
KM410_16515	COG0346	lactoylglutathione lyase activity
KM410_16520	COG0814	amino acid
KM410_16545	COG1393	Belongs to the ArsC family
KM410_16550	COG1733	regulation of RNA biosynthetic process
KM410_16555	COG2188	Transcriptional regulator
KM410_16565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM410_16570	COG1733	regulation of RNA biosynthetic process
KM410_16575	COG1733	regulation of RNA biosynthetic process
KM410_16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_16610	COG0384	phenazine biosynthesis protein PhzF
KM410_16620	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_16630	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_16640	COG1733	regulation of RNA biosynthetic process
KM410_16675	COG1191	sigma factor activity
KM410_16690	COG1309	transcriptional regulator
KM410_16710	COG3152	Membrane
KM410_16735	COG1151	hydroxylamine reductase activity
KM410_16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_16750	COG3757	hydrolase, family 25
KM410_16750	COG3409	Peptidoglycan-binding domain 1 protein
KM410_16785	COG2072	flavoprotein involved in K transport
KM410_16820	COG0604	alcohol dehydrogenase
KM410_16825	COG1113	amino acid transport
KM410_16830	COG2814	Major facilitator Superfamily
KM410_16860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM410_16865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM410_16885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_16890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_16900	COG3739	integral membrane protein
KM410_16905	COG0384	phenazine biosynthesis protein PhzF
KM410_16935	COG0583	DNA-binding transcription factor activity
KM410_16955	COG1193	negative regulation of DNA recombination
KM410_16980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM410_17010	COG0584	glycerophosphoryl diester phosphodiesterase
KM410_17035	COG0640	Transcriptional regulator
KM410_17040	COG0604	alcohol dehydrogenase
KM410_17060	COG2808	Putative FMN-binding domain
KM410_17065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM410_17075	COG0385	Bile acid
KM410_17080	COG0277	FAD linked oxidase domain protein
KM410_17110	COG1216	Glycosyl transferase, family 2
KM410_17115	COG1024	Enoyl-CoA hydratase
KM410_17125	COG1285	pathogenesis
KM410_17140	COG2514	catechol 2,3-dioxygenase activity
KM410_17145	COG2720	vancomycin resistance protein
KM410_17185	COG0716	FMN binding
KM410_17215	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_17225	COG0165	Argininosuccinate lyase
KM410_17240	COG4145	pantothenate transmembrane transporter activity
KM410_17250	COG1012	belongs to the aldehyde dehydrogenase family
KM410_17255	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_17265	COG1657	PFAM Prenyltransferase squalene oxidase
KM410_17270	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM410_17275	COG2962	Rard protein
KM410_17280	COG3326	Membrane
KM410_17295	COG0489	protein tyrosine kinase activity
KM410_17305	COG0314	molybdopterin synthase activity
KM410_17310	COG0303	'Molybdopterin
KM410_17315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM410_17320	COG2116	formate transmembrane transporter activity
KM410_17330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM410_17335	COG5609	conserved protein (DUF2294)
KM410_17340	COG2427	Protein of unknown function (DUF1641)
KM410_17345	COG3383	formate dehydrogenase (NAD+) activity
KM410_17355	COG0697	spore germination
KM410_17395	COG2226	methyltransferase
KM410_17400	COG4166	transmembrane transport
KM410_17405	COG4166	transmembrane transport
KM410_17410	COG4166	transmembrane transport
KM410_17415	COG1301	dicarboxylic acid transport
KM410_17420	COG1316	TRANSCRIPTIONal
KM410_17430	COG1595	DNA-templated transcription, initiation
KM410_17450	COG1131	(ABC) transporter
KM410_17460	COG0673	inositol 2-dehydrogenase activity
KM410_17465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM410_17470	COG0187	DNA topoisomerase II activity
KM410_17475	COG1832	CoA-binding protein
KM410_17480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM410_17485	COG0745	RESPONSE REGULATOR receiver
KM410_17500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM410_17505	COG4841	protein insertion into membrane
KM410_17510	COG0824	Thioesterase
KM410_17540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM410_17550	COG2274	protein secretion by the type I secretion system
KM410_17555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM410_17595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM410_17610	COG0183	Belongs to the thiolase family
KM410_17615	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_17620	COG1268	BioY protein
KM410_17625	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_17675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_17685	COG5002	protein histidine kinase activity
KM410_17690	COG0400	carboxylic ester hydrolase activity
KM410_17695	COG0346	lactoylglutathione lyase activity
KM410_17700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM410_17705	COG0069	glutamate synthase activity
KM410_17710	COG1902	pentaerythritol trinitrate reductase activity
KM410_17715	COG1329	Transcriptional regulator
KM410_17720	COG0010	Belongs to the arginase family
KM410_17745	COG2226	methyltransferase
KM410_17800	COG4846	Membrane protein involved in cytochrome C biogenesis
KM410_17805	COG0785	Cytochrome C biogenesis protein
KM410_17815	COG0583	DNA-binding transcription factor activity
KM410_17820	COG1380	Effector of murein hydrolase LrgA
KM410_17825	COG1346	cytolysis
KM410_17850	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM410_17850	COG3409	Peptidoglycan-binding domain 1 protein
KM410_17865	COG1132	(ABC) transporter
KM410_17870	COG1132	(ABC) transporter
KM410_17900	COG3639	organic phosphonate transmembrane transporter activity
KM410_17905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM410_17925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM410_17945	COG1695	Transcriptional regulator
KM410_17980	COG1388	LysM domain
KM410_17980	COG3409	Peptidoglycan-binding domain 1 protein
KM410_17980	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM410_17985	COG4824	toxin secretion phage lysis holin
KM410_18140	COG1595	DNA-templated transcription, initiation
KM410_18185	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM410_18270	COG1396	sequence-specific DNA binding
KM410_18295	COG0174	glutamine synthetase
KM410_18300	COG0789	Transcriptional regulator
KM410_18305	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM410_18315	COG2860	membrane
KM410_18325	COG0464	growth
KM410_18355	COG3584	3D domain protein
KM410_18355	COG1388	LysM domain
KM410_18360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM410_18360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM410_18360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM410_18365	COG1105	Belongs to the carbohydrate kinase PfkB family
KM410_18370	COG1349	DNA-binding transcription factor activity
KM410_18380	COG2322	membrane
KM410_18390	COG1113	amino acid transport
KM410_18405	COG1408	metallophosphoesterase
KM410_18410	COG2116	formate transmembrane transporter activity
KM410_18420	COG2217	Heavy metal translocating P-type atpase
KM410_18425	COG2608	mercury ion transmembrane transporter activity
KM410_18430	COG1937	Protein conserved in bacteria
KM410_18440	COG2819	hydrolase of the alpha beta superfamily
KM410_18445	COG1120	ATPase activity
KM410_18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_18465	COG0708	Exodeoxyribonuclease III
KM410_18470	COG2169	Transcriptional regulator
KM410_18475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM410_18480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM410_18490	COG2364	Membrane
KM410_18505	COG2267	carboxylic ester hydrolase activity
KM410_18510	COG0346	lactoylglutathione lyase activity
KM410_18515	COG3300	MHYT domain
KM410_18515	COG5001	Diguanylate cyclase
KM410_18530	COG1346	cytolysis
KM410_18535	COG1380	Effector of murein hydrolase LrgA
KM410_18540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM410_18545	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM410_18545	COG0596	Alpha beta hydrolase
KM410_18550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM410_18570	COG1404	Belongs to the peptidase S8 family
KM410_18575	COG3773	Cell wall hydrolase
KM410_18580	COG0562	UDP-galactopyranose mutase
KM410_18585	COG1368	sulfuric ester hydrolase activity
KM410_18590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM410_18600	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM410_18625	COG1131	(ABC) transporter
KM410_18645	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM410_18650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM410_18655	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM410_18660	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM410_18660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM410_18670	COG2359	stage V sporulation protein S
KM410_18675	COG1692	metallophosphoesterase
KM410_18700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM410_18705	COG1426	Protein conserved in bacteria
KM410_18720	COG0300	oxidoreductase activity
KM410_18725	COG0612	Peptidase, M16
KM410_18730	COG0612	Peptidase, M16
KM410_18735	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM410_18745	COG3845	ABC transporter
KM410_18750	COG1744	ABC transporter substrate-binding protein PnrA-like
KM410_18755	COG2188	Transcriptional regulator
KM410_18760	COG1674	ftsk spoiiie
KM410_18770	COG0740	serine-type endopeptidase activity
KM410_18775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM410_18790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM410_18795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM410_18800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM410_18805	COG1873	PFAM PRC-barrel domain
KM410_18810	COG0612	Peptidase, M16
KM410_18815	COG0726	polysaccharide deacetylase
KM410_18830	COG0196	riboflavin kinase activity
KM410_18835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM410_18845	COG1550	Protein conserved in bacteria
KM410_18855	COG1358	cellular component organization or biogenesis
KM410_18860	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM410_18865	COG0195	Participates in both transcription termination and antitermination
KM410_18885	COG0750	zinc metalloprotease
KM410_18895	COG4589	Belongs to the CDS family
KM410_18900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM410_18910	COG0528	UMP kinase activity
KM410_18940	COG4974	Belongs to the 'phage' integrase family
KM410_18950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM410_18960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM410_19000	COG1837	Belongs to the UPF0109 family
KM410_19010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM410_19020	COG0552	protein localization to endoplasmic reticulum
KM410_19025	COG1196	nuclear chromosome segregation
KM410_19035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM410_19040	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_19045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM410_19060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM410_19065	COG1461	Dihydroxyacetone kinase
KM410_19070	COG1302	Protein conserved in bacteria
KM410_19085	COG1564	THIamine pyrophosphokinase
KM410_19090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM410_19095	COG1162	GTPase activity
KM410_19100	COG0515	serine threonine protein kinase
KM410_19100	COG2815	serine threonine protein kinase
KM410_19105	COG0631	protein serine/threonine phosphatase activity
KM410_19115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM410_19115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM410_19125	COG0242	peptide deformylase activity
KM410_19130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM410_19135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM410_19155	COG1561	YicC-like family, N-terminal region
KM410_19160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM410_19170	COG0006	proline dipeptidase activity
KM410_19185	COG3069	C4-dicarboxylate transmembrane transporter activity
KM410_19250	COG0564	pseudouridine synthase activity
KM410_19270	COG3599	regulation of cell shape
KM410_19275	COG2302	S4 RNA-binding domain
KM410_19280	COG0762	integral membrane protein
KM410_19290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM410_19295	COG1496	oxidoreductase activity
KM410_19300	COG1873	PFAM PRC-barrel domain
KM410_19305	COG1191	sigma factor activity
KM410_19310	COG1191	sigma factor activity
KM410_19320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM410_19325	COG0849	cell division
KM410_19330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM410_19335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM410_19345	COG0772	Belongs to the SEDS family
KM410_19360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM410_19365	COG0768	penicillin binding
KM410_19370	COG0768	penicillin binding
KM410_19375	COG4839	cell division protein FtsL
KM410_19390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM410_19405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM410_19410	COG1399	metal-binding, possibly nucleic acid-binding protein
KM410_19460	COG4824	toxin secretion phage lysis holin
KM410_19545	COG1802	Transcriptional regulator
KM410_19545	COG4626	Terminase
KM410_19570	COG0582	viral genome integration into host DNA
KM410_19635	COG0756	dUTP diphosphatase activity
KM410_19650	COG1191	sigma factor activity
KM410_19675	COG1484	DNA-dependent DNA replication
KM410_19705	COG1396	sequence-specific DNA binding
KM410_19720	COG1396	sequence-specific DNA binding
KM410_19735	COG0582	viral genome integration into host DNA
KM410_19745	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM410_19750	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM410_19755	COG3314	Sporulation integral membrane protein YlbJ
KM410_19765	COG0742	ribosomal rna small subunit methyltransferase
KM410_19780	COG3679	Belongs to the UPF0342 family
KM410_19785	COG0406	alpha-ribazole phosphatase activity
KM410_19800	COG2340	Cysteine-rich secretory protein family
KM410_19815	COG3336	cytochrome c oxidase
KM410_19850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM410_19855	COG0772	Belongs to the SEDS family
KM410_19865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM410_19870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM410_19880	COG4896	Protein conserved in bacteria
KM410_19895	COG1217	gtp-binding protein TYPA
KM410_19905	COG0483	inositol monophosphate 1-phosphatase activity
KM410_19925	COG1982	Orn Lys Arg decarboxylase major
KM410_19970	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM410_19975	COG0022	dehydrogenase e1 component
KM410_19980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM410_19990	COG0242	peptide deformylase activity
KM410_19995	COG0561	phosphatase activity
KM410_20005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM410_20010	COG0569	domain protein
KM410_20030	COG0583	DNA-binding transcription factor activity
KM410_20035	COG0517	IMP dehydrogenase activity
KM410_20045	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM410_20055	COG4703	Protein of unknown function (DUF1797)
KM410_20070	COG2200	EAL domain
KM410_20075	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_20080	COG1408	metallophosphoesterase
KM410_20090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM410_20125	COG2814	Major facilitator Superfamily
KM410_20145	COG3209	COG3209 Rhs family protein
KM410_20155	COG2205	protein histidine kinase activity
KM410_20165	COG0436	Aminotransferase
KM410_20170	COG1609	Transcriptional regulator
KM410_20175	COG3833	ABC-type maltose transport systems, permease component
KM410_20180	COG1175	transmembrane transport
KM410_20185	COG2182	Extracellular solute-binding protein
KM410_20195	COG0366	Alpha amylase catalytic
KM410_20200	COG3842	ATPase activity
KM410_20240	COG0183	Belongs to the thiolase family
KM410_20275	COG1695	Transcriptional regulator
KM410_20280	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_20290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM410_20300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM410_20305	COG0436	Aminotransferase
KM410_20325	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM410_20345	COG2199	diguanylate cyclase activity
KM410_20350	COG0778	Nitroreductase
KM410_20375	COG2190	(PTS) system
KM410_20375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM410_20375	COG1263	PTS System
KM410_20380	COG3711	transcriptional antiterminator
KM410_20390	COG2188	Transcriptional regulator
KM410_20400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM410_20425	COG1547	Domain of unknown function (DUF309)
KM410_20430	COG0456	acetyltransferase
KM410_20435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM410_20440	COG4086	secreted protein
KM410_20445	COG0561	phosphatase activity
KM410_20450	COG0697	spore germination
KM410_20465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_20490	COG0733	neurotransmitter:sodium symporter activity
KM410_20510	COG1686	Belongs to the peptidase S11 family
KM410_20515	COG1725	Transcriptional regulator
KM410_20520	COG1131	(ABC) transporter
KM410_20535	COG1846	Transcriptional regulator
KM410_20550	COG0598	Magnesium transport protein CorA
KM410_20575	COG4974	Belongs to the 'phage' integrase family
KM410_20585	COG0735	belongs to the Fur family
KM410_20590	COG1300	Membrane
KM410_20610	COG0667	Aldo Keto reductase
KM410_20615	COG0656	L-ascorbic acid biosynthetic process
KM410_20620	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM410_20620	COG0456	acetyltransferase
KM410_20630	COG4085	toxin activity
KM410_20630	COG0737	Belongs to the 5'-nucleotidase family
KM410_20630	COG1525	nuclease
KM410_20640	COG0596	Alpha beta hydrolase
KM410_20645	COG2056	Na+-H+ antiporter family
KM410_20650	COG1609	Transcriptional regulator
KM410_20655	COG0456	acetyltransferase
KM410_20660	COG1073	alpha beta
KM410_20675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM410_20675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM410_20680	COG0307	riboflavin synthase, alpha
KM410_20705	COG4106	trans-aconitate 2-methyltransferase activity
KM410_20710	COG2226	methyltransferase
KM410_20710	COG1073	alpha beta
KM410_20725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM410_20735	COG1757	Na H antiporter
KM410_20740	COG0737	Belongs to the 5'-nucleotidase family
KM410_20750	COG1522	sequence-specific DNA binding
KM410_20770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM410_20780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM410_20795	COG0300	oxidoreductase activity
KM410_20805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM410_20810	COG1760	l-serine dehydratase
KM410_20815	COG1760	l-serine dehydratase
KM410_20835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM410_20845	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM410_20850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_20865	COG1376	ErfK ybiS ycfS ynhG family protein
KM410_20870	COG4129	membrane
KM410_20875	COG1126	abc transporter atp-binding protein
KM410_20880	COG0765	amino acid transport
KM410_20885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM410_20905	COG0772	Belongs to the SEDS family
KM410_20910	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM410_20915	COG0022	dehydrogenase e1 component
KM410_20920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM410_20925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM410_20940	COG0280	phosphate acetyltransferase
KM410_20945	COG3829	transcription factor binding
KM410_20945	COG3290	protein histidine kinase activity
KM410_20955	COG0584	glycerophosphoryl diester phosphodiesterase
KM410_20960	COG3093	addiction module antidote protein HigA
KM410_20970	COG0745	RESPONSE REGULATOR receiver
KM410_20975	COG0750	zinc metalloprotease
KM410_20980	COG0497	DNA recombination
KM410_20990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM410_21000	COG0142	geranyltranstransferase activity
KM410_21025	COG1302	Protein conserved in bacteria
KM410_21030	COG0439	Biotin carboxylase
KM410_21035	COG0511	ligase activity, forming carbon-carbon bonds
KM410_21080	COG3854	ATPases associated with a variety of cellular activities
KM410_21105	COG0006	proline dipeptidase activity
KM410_21120	COG3872	metal-dependent enzyme
KM410_21130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM410_21150	COG0095	Lipoate-protein ligase
KM410_21155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_21160	COG1609	Transcriptional regulator
KM410_21170	COG2076	Multidrug Resistance protein
KM410_21175	COG2076	Multidrug Resistance protein
KM410_21210	COG1131	(ABC) transporter
KM410_21215	COG1725	Transcriptional regulator
KM410_21245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM410_21300	COG4970	Tfp pilus assembly protein FimT
KM410_21310	COG1459	type II secretion system
KM410_21315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM410_21365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM410_21370	COG1410	methionine synthase
KM410_21370	COG0646	methionine synthase
KM410_21375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM410_21375	COG0646	methionine synthase
KM410_21380	COG0626	cystathionine gamma-synthase activity
KM410_21385	COG0626	cystathionine gamma-synthase activity
KM410_21405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_21415	COG1940	carbohydrate kinase activity
KM410_21420	COG4483	Protein conserved in bacteria
KM410_21425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM410_21430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM410_21435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM410_21440	COG0704	Plays a role in the regulation of phosphate uptake
KM410_21450	COG0581	inorganic phosphate transmembrane transporter activity
KM410_21455	COG0573	inorganic phosphate transmembrane transporter activity
KM410_21460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM410_21465	COG0768	penicillin binding
KM410_21470	COG0477	Major facilitator Superfamily
KM410_21475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM410_21500	COG0735	belongs to the Fur family
KM410_21505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM410_21510	COG1121	(ABC) transporter
KM410_21515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_21545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM410_21550	COG2384	SAM-dependent methyltransferase
KM410_21555	COG2010	Cytochrome c
KM410_21560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM410_21565	COG0358	DNA primase activity
KM410_21580	COG0517	IMP dehydrogenase activity
KM410_21595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM410_21600	COG0295	cytidine deaminase activity
KM410_21605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM410_21615	COG1480	7TM receptor with intracellular HD hydrolase
KM410_21620	COG1702	phosphate starvation-inducible protein PhoH
KM410_21635	COG1610	YqeY-like protein
KM410_21640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM410_21645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM410_21650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM410_21680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM410_21685	COG1733	regulation of RNA biosynthetic process
KM410_21710	COG1466	dna polymerase III delta subunit
KM410_21720	COG0658	competence protein
KM410_21720	COG2333	competence protein COMEC
KM410_21725	COG2131	deaminase
KM410_21730	COG1596	polysaccharide export
KM410_21730	COG1555	photosystem II stabilization
KM410_21735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM410_21740	COG2226	methyltransferase
KM410_21745	COG0799	negative regulation of ribosome biogenesis
KM410_21760	COG1534	Rna-binding protein
KM410_21770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM410_21775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM410_21800	COG1595	DNA-templated transcription, initiation
KM410_21810	COG0778	Nitroreductase
KM410_21815	COG2357	RelA SpoT domain protein
KM410_21825	COG1785	Belongs to the alkaline phosphatase family
KM410_21835	COG2267	carboxylic ester hydrolase activity
KM410_21870	COG1404	Belongs to the peptidase S8 family
KM410_21875	COG3186	Phenylalanine-4-hydroxylase
KM410_21890	COG2259	Doxx family
KM410_21930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_21940	COG1454	alcohol dehydrogenase
KM410_21940	COG1012	belongs to the aldehyde dehydrogenase family
KM410_21945	COG0626	cystathionine gamma-synthase activity
KM410_21950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM410_21975	COG0768	penicillin binding
KM410_21990	COG0826	peptidase U32
KM410_21995	COG0826	peptidase U32
KM410_22000	COG4122	O-methyltransferase activity
KM410_22005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM410_22025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM410_22035	COG0628	permease
KM410_22055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM410_22065	COG0482	sulfurtransferase activity
KM410_22070	COG1104	cysteine desulfurase activity
KM410_22075	COG1959	2 iron, 2 sulfur cluster binding
KM410_22080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM410_22090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM410_22115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM410_22125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM410_22125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM410_22130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM410_22135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM410_22135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM410_22145	COG2244	polysaccharide biosynthetic process
KM410_22150	COG2323	membrane
KM410_22160	COG1862	Preprotein translocase
KM410_22190	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM410_22200	COG0697	spore germination
KM410_22205	COG0697	spore germination
KM410_22210	COG0640	Transcriptional regulator
KM410_22235	COG0157	Belongs to the NadC ModD family
KM410_22240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM410_22245	COG1104	cysteine desulfurase activity
KM410_22250	COG1827	regulation of RNA biosynthetic process
KM410_22255	COG2258	MOSC domain
KM410_22260	COG0077	Prephenate dehydratase
KM410_22265	COG0577	efflux transmembrane transporter activity
KM410_22270	COG0577	efflux transmembrane transporter activity
KM410_22275	COG1136	(ABC) transporter
KM410_22285	COG0745	RESPONSE REGULATOR receiver
KM410_22290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM410_22295	COG3290	protein histidine kinase activity
KM410_22305	COG2868	ribosomal protein
KM410_22315	COG1530	ribonuclease E activity
KM410_22320	COG1994	Peptidase M50
KM410_22325	COG0739	heme binding
KM410_22330	COG2894	cell division
KM410_22350	COG1077	Cell shape determining protein MreB Mrl
KM410_22370	COG0285	dihydrofolate synthase activity
KM410_22375	COG0525	valine-tRNA ligase activity
KM410_22385	COG1388	LysM domain
KM410_22395	COG0113	porphobilinogen synthase activity
KM410_22400	COG1587	Uroporphyrinogen-III synthase
KM410_22410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM410_22420	COG1846	Transcriptional regulator
KM410_22425	COG1764	response to oxidative stress
KM410_22440	COG0470	DNA polymerase III
KM410_22440	COG1067	ATP-dependent peptidase activity
KM410_22485	COG0622	Phosphoesterase
KM410_22500	COG5401	PFAM Sporulation and spore germination
KM410_22520	COG1309	transcriptional regulator
KM410_22535	COG2197	response regulator
KM410_22540	COG2233	PERMEase
KM410_22550	COG0402	S-adenosylhomocysteine deaminase activity
KM410_22555	COG0402	S-adenosylhomocysteine deaminase activity
KM410_22565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM410_22575	COG0444	Belongs to the ABC transporter superfamily
KM410_22580	COG4608	Belongs to the ABC transporter superfamily
KM410_22585	COG3275	phosphorelay sensor kinase activity
KM410_22590	COG3279	Response regulator of the LytR AlgR family
KM410_22605	COG1983	PspC domain protein
KM410_22610	COG1396	sequence-specific DNA binding
KM410_22615	COG0697	spore germination
KM410_22625	COG1959	2 iron, 2 sulfur cluster binding
KM410_22630	COG1668	transmembrane transport
KM410_22635	COG4152	abc transporter atp-binding protein
KM410_22640	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM410_22650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM410_22655	COG1876	peptidase activity
KM410_22660	COG0824	Thioesterase
KM410_22665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM410_22670	COG1053	succinate dehydrogenase
KM410_22675	COG2009	succinate dehydrogenase
KM410_22680	COG1719	4-vinyl reductase, 4VR
KM410_22690	COG3118	belongs to the thioredoxin family
KM410_22695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM410_22700	COG2086	electron transfer activity
KM410_22705	COG1024	Enoyl-CoA hydratase
KM410_22710	COG1309	transcriptional regulator
KM410_22715	COG0318	PFAM AMP-dependent synthetase and ligase
KM410_22735	COG2318	DinB family
KM410_22765	COG1131	(ABC) transporter
KM410_22770	COG2205	protein histidine kinase activity
KM410_22775	COG0745	RESPONSE REGULATOR receiver
KM410_22785	COG4895	conserved protein (DUF2196)
KM410_22790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM410_22805	COG4509	Sortase family
KM410_22810	COG1120	ATPase activity
KM410_22825	COG5386	Cell surface protein
KM410_22835	COG5386	Cell surface protein
KM410_22840	COG1114	Component of the transport system for branched-chain amino acids
KM410_22845	COG1187	pseudouridine synthase activity
KM410_22855	COG1796	DNA polymerase
KM410_22855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM410_22860	COG1286	toxin biosynthetic process
KM410_22905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM410_22915	COG1418	mRNA catabolic process
KM410_22940	COG2814	Major facilitator Superfamily
KM410_22945	COG1566	PFAM secretion protein HlyD family protein
KM410_22950	COG1309	transcriptional regulator
KM410_22955	COG1363	Peptidase, m42
KM410_22980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM410_22990	COG1484	DNA-dependent DNA replication
KM410_22995	COG3611	Membrane attachment protein
KM410_23005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM410_23010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM410_23015	COG0237	dephospho-CoA kinase activity
KM410_23020	COG1971	Probably functions as a manganese efflux pump
KM410_23030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM410_23030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM410_23035	COG5002	protein histidine kinase activity
KM410_23040	COG0745	RESPONSE REGULATOR receiver
KM410_23060	COG0538	isocitrate dehydrogenase activity
KM410_23065	COG0372	Belongs to the citrate synthase family
KM410_23075	COG0628	permease
KM410_23080	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM410_23105	COG1725	Transcriptional regulator
KM410_23110	COG0281	malic enzyme
KM410_23115	COG0587	DNA-directed DNA polymerase activity
KM410_23130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM410_23150	COG4109	DRTGG domain
KM410_23165	COG0006	proline dipeptidase activity
KM410_23200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_23205	COG0662	Cupin 2, conserved barrel domain protein
KM410_23215	COG1476	TRANSCRIPTIONal
KM410_23230	COG1028	Short-chain dehydrogenase reductase Sdr
KM410_23235	COG0589	response to stress
KM410_23275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_23295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM410_23300	COG0827	DNA restriction-modification system
KM410_23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM410_23310	COG3874	Sporulation protein YtfJ
KM410_23325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM410_23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM410_23350	COG1104	cysteine desulfurase activity
KM410_23360	COG0583	DNA-binding transcription factor activity
KM410_23365	COG0697	spore germination
KM410_23375	COG1956	GAF domain-containing protein
KM410_23380	COG0626	cystathionine gamma-synthase activity
KM410_23410	COG1595	DNA-templated transcription, initiation
KM410_23420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM410_23425	COG0454	-acetyltransferase
KM410_23430	COG0517	IMP dehydrogenase activity
KM410_23435	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM410_23445	COG0745	RESPONSE REGULATOR receiver
KM410_23455	COG0666	response to abiotic stimulus
KM410_23490	COG1609	Transcriptional regulator
KM410_23495	COG4851	CamS sex pheromone cAM373 precursor
KM410_23500	COG3118	belongs to the thioredoxin family
KM410_23510	COG2309	aminopeptidase activity
KM410_23530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_23545	COG1674	ftsk spoiiie
KM410_23555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM410_23560	COG4848	Belongs to the UPF0354 family
KM410_23565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM410_23570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM410_23575	COG1363	Peptidase, m42
KM410_23585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_23600	COG0510	thiamine kinase activity
KM410_23605	COG1523	belongs to the glycosyl hydrolase 13 family
KM410_23620	COG1349	DNA-binding transcription factor activity
KM410_23625	COG1187	pseudouridine synthase activity
KM410_23630	COG2244	polysaccharide biosynthetic process
KM410_23635	COG2081	HI0933 family
KM410_23640	COG2814	Major facilitator Superfamily
KM410_23650	COG3832	glyoxalase III activity
KM410_23670	COG1329	Transcriptional regulator
KM410_23680	COG4975	Glucose uptake
KM410_23695	COG0314	molybdopterin synthase activity
KM410_23700	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM410_23705	COG0303	'Molybdopterin
KM410_23715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM410_23740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM410_23750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM410_23795	COG2814	Major facilitator Superfamily
KM410_23800	COG0475	glutathione-regulated potassium exporter activity
KM410_23805	COG0490	domain, Protein
KM410_23810	COG0582	viral genome integration into host DNA
KM410_23820	COG1136	(ABC) transporter
KM410_23840	COG1242	4 iron, 4 sulfur cluster binding
KM410_23845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM410_23850	COG1131	(ABC) transporter
KM410_23860	COG1794	racemase activity, acting on amino acids and derivatives
KM410_23880	COG2267	carboxylic ester hydrolase activity
KM410_23885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM410_23890	COG0671	phosphoesterase, PA-phosphatase related
KM410_23895	COG0438	transferase activity, transferring glycosyl groups
KM410_23905	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM410_23960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM410_23965	COG5002	protein histidine kinase activity
KM410_23970	COG4191	Histidine kinase
KM410_23975	COG2267	carboxylic ester hydrolase activity
KM410_23995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM410_24000	COG1116	anion transmembrane transporter activity
KM410_24005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM410_24030	COG0494	nUDIX hydrolase
KM410_24060	COG0288	reversible hydration of carbon dioxide
KM410_24065	COG1271	oxidase subunit
KM410_24070	COG1294	oxidase, subunit
KM410_24090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_24115	COG1842	Phage shock protein A
KM410_24145	COG5002	protein histidine kinase activity
KM410_24150	COG0745	RESPONSE REGULATOR receiver
KM410_24180	COG1597	lipid kinase activity
KM410_24215	COG0586	Pfam SNARE associated Golgi protein
KM410_24225	COG0577	efflux transmembrane transporter activity
KM410_24230	COG1136	(ABC) transporter
KM410_24235	COG3708	Transcriptional regulator
KM410_24235	COG2207	Transcriptional regulator
KM410_24240	COG0745	RESPONSE REGULATOR receiver
KM410_24245	COG2205	protein histidine kinase activity
KM410_24250	COG0577	efflux transmembrane transporter activity
KM410_24260	COG0577	efflux transmembrane transporter activity
KM410_24265	COG1136	(ABC) transporter
KM410_24285	COG2188	Transcriptional regulator
KM410_24305	COG3964	amidohydrolase
KM410_24335	COG4948	Mandelate Racemase Muconate Lactonizing
KM410_24345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM410_24350	COG0596	Alpha beta hydrolase
KM410_24355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM410_24360	COG1169	isochorismate synthase
KM410_24365	COG1575	Belongs to the MenA family. Type 1 subfamily
KM410_24370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM410_24390	COG0058	SHG alpha-glucan phosphorylase activity
KM410_24395	COG0297	glycogen (starch) synthase activity
KM410_24400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM410_24520	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM410_24555	COG1285	pathogenesis
KM410_24560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM410_24570	COG0166	Belongs to the GPI family
KM410_24575	COG2155	Conserved Protein
KM410_24580	COG1098	S1 RNA binding domain
KM410_24585	COG0436	Aminotransferase
KM410_24590	COG1522	sequence-specific DNA binding
KM410_24595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM410_24600	COG2267	carboxylic ester hydrolase activity
KM410_24610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM410_24630	COG5018	Exonuclease
KM410_24635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM410_24655	COG2050	protein possibly involved in aromatic compounds catabolism
KM410_24665	COG1268	BioY protein
KM410_24675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM410_24680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM410_24695	COG3584	3D domain protein
KM410_24710	COG1252	NADH dehydrogenase
KM410_24725	COG3708	Transcriptional regulator
KM410_24740	COG1683	Conserved Protein
KM410_24760	COG0316	Belongs to the HesB IscA family
KM410_24775	COG1252	NADH dehydrogenase
KM410_24790	COG0390	transport system, permease component
KM410_24795	COG2824	Alkylphosphonate utilization operon protein PhnA
KM410_24835	COG4837	Protein of unknown function (DUF1462)
KM410_24840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM410_24850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM410_24855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM410_24865	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM410_24870	COG0647	UMP catabolic process
KM410_24880	COG2445	Protein of unknown function DUF86
KM410_24885	COG1494	fructose-1,6-bisphosphatase
KM410_24900	COG4470	Protein conserved in bacteria
KM410_24910	COG0789	Transcriptional regulator
KM410_24915	COG4377	Putative membrane peptidase family (DUF2324)
KM410_24940	COG0739	heme binding
KM410_24950	COG3377	Domain of unknown function (DUF1805)
KM410_24955	COG0737	Belongs to the 5'-nucleotidase family
KM410_24960	COG1695	Transcriptional regulator
KM410_24970	COG0719	Fe-S assembly protein
KM410_24975	COG0822	iron-sulfur transferase activity
KM410_24980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM410_24985	COG0719	Fe-S assembly protein
KM410_24990	COG0396	ATPase activity
KM410_24995	COG1464	Belongs to the NlpA lipoprotein family
KM410_25000	COG1464	Belongs to the NlpA lipoprotein family
KM410_25005	COG2011	ABC-type metal ion transport system permease component
KM410_25010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM410_25020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM410_25025	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM410_25035	COG1393	Belongs to the ArsC family
KM410_25080	COG0039	L-malate dehydrogenase activity
KM410_25100	COG1309	transcriptional regulator
KM410_25105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM410_25110	COG1960	acyl-CoA dehydrogenase activity
KM410_25115	COG0183	Belongs to the thiolase family
KM410_25120	COG1024	Enoyl-CoA hydratase
KM410_25120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM410_25130	COG1686	Belongs to the peptidase S11 family
KM410_25145	COG0011	TIGRFAM Protein of
KM410_25150	COG0840	transmembrane signaling receptor activity
KM410_25170	COG2814	Major facilitator Superfamily
KM410_25175	COG0531	amino acid
KM410_25185	COG0706	membrane insertase activity
KM410_25195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM410_25230	COG0586	Pfam SNARE associated Golgi protein
KM410_25240	COG1376	ErfK ybiS ycfS ynhG family protein
KM410_25245	COG0745	RESPONSE REGULATOR receiver
KM410_25250	COG5002	protein histidine kinase activity
KM410_25275	COG2151	metal-sulfur cluster biosynthetic enzyme
KM410_25280	COG3227	Zinc metalloprotease (Elastase)
KM410_25285	COG1741	Belongs to the pirin family
KM410_25300	COG0475	glutathione-regulated potassium exporter activity
KM410_25305	COG0490	domain, Protein
KM410_25310	COG1115	amino acid carrier protein
KM410_25315	COG0783	Belongs to the Dps family
KM410_25330	COG1611	Belongs to the LOG family
KM410_25350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_25355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_25360	COG1115	amino acid carrier protein
KM410_25365	COG1115	amino acid carrier protein
KM410_25370	COG2910	NAD(P)H-binding
KM410_25385	COG0656	L-ascorbic acid biosynthetic process
KM410_25390	COG2814	Major facilitator Superfamily
KM410_25395	COG1733	regulation of RNA biosynthetic process
KM410_25405	COG1252	NADH dehydrogenase
KM410_25410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM410_25415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM410_25425	COG0840	transmembrane signaling receptor activity
KM410_25425	COG3290	protein histidine kinase activity
KM410_25435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM410_25440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM410_25455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM410_25510	COG0557	exoribonuclease II activity
KM410_25515	COG1647	Serine aminopeptidase, S33
KM410_25520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM410_25525	COG1346	cytolysis
KM410_25625	COG4695	Portal protein
KM410_25650	COG4974	Belongs to the 'phage' integrase family
KM410_25660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM410_25665	COG0149	triose-phosphate isomerase activity
KM410_25675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM410_25690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM410_25715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM410_25730	COG2323	membrane
KM410_25735	COG0740	serine-type endopeptidase activity
KM410_25740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM410_25750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM410_25760	COG1051	belongs to the nudix hydrolase family
KM410_25770	COG0492	ferredoxin-NADP+ reductase activity
KM410_25775	COG0457	Tetratricopeptide repeat
KM410_25780	COG0110	maltose O-acetyltransferase activity
KM410_25800	COG1950	PFAM Membrane protein of
KM410_25810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM410_25815	COG0556	nucleotide-excision repair
KM410_25835	COG0789	Transcriptional regulator
KM410_25860	COG2855	membrane
KM410_25865	COG0583	DNA-binding transcription factor activity
KM410_25875	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM410_25880	COG0488	(ABC) transporter
KM410_25890	COG1132	(ABC) transporter
KM410_25895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM410_25900	COG0793	Belongs to the peptidase S41A family
KM410_25900	COG3409	Peptidoglycan-binding domain 1 protein
KM410_25905	COG2177	Part of the ABC transporter FtsEX involved in
KM410_25910	COG2884	Cell division ATP-binding protein ftsE
KM410_25925	COG0653	protein targeting
KM410_25930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM410_25935	COG1278	Cold shock
KM410_25940	COG1040	competence protein
KM410_25945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM410_25950	COG0791	NLP P60 protein
KM410_25950	COG1388	LysM domain
KM410_25955	COG1733	regulation of RNA biosynthetic process
KM410_25960	COG1307	EDD domain protein, DegV family
KM410_25965	COG1739	Uncharacterized protein family UPF0029
KM410_25970	COG1316	TRANSCRIPTIONal
KM410_25975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM410_25980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM410_25985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM410_25995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM410_25995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM410_26010	COG3394	polysaccharide catabolic process
KM410_26015	COG1486	melibiose metabolic process
KM410_26020	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM410_26025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM410_26035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM410_26040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM410_26045	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM410_26055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM410_26060	COG1301	dicarboxylic acid transport
KM410_26070	COG0346	lactoylglutathione lyase activity
KM410_26075	COG1511	domain protein
KM410_26080	COG0583	DNA-binding transcription factor activity
KM410_26085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM410_26100	COG1271	oxidase subunit
KM410_26105	COG1294	oxidase, subunit
KM410_26110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM410_26130	COG2389	metal-binding protein
KM410_26140	COG1368	sulfuric ester hydrolase activity
KM410_26155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM410_26165	COG1215	transferase activity, transferring glycosyl groups
KM410_26170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM410_26175	COG1388	LysM domain
KM410_26175	COG3584	3D domain protein
KM410_26200	COG4715	Zinc finger, swim domain protein
KM410_26205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM410_26245	COG0577	efflux transmembrane transporter activity
KM410_26250	COG1136	(ABC) transporter
KM410_26285	COG5002	protein histidine kinase activity
KM410_26290	COG0745	RESPONSE REGULATOR receiver
KM410_26295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM410_26310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM410_26315	COG1134	teichoic acid transport
KM410_26320	COG1682	transport, permease protein
KM410_26325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM410_26370	COG1609	Transcriptional regulator
KM410_26385	COG0739	heme binding
KM410_26405	COG2385	sporulation resulting in formation of a cellular spore
KM410_26420	COG4836	Membrane
KM410_26425	COG1007	ATP synthesis coupled electron transport
KM410_26430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM410_26435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM410_26445	COG0839	Belongs to the complex I subunit 6 family
KM410_26460	COG0649	NAD binding
KM410_26465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM410_26480	COG3300	MHYT domain
KM410_26480	COG5001	Diguanylate cyclase
KM410_26530	COG0356	it plays a direct role in the translocation of protons across the membrane
KM410_26565	COG0698	ribose 5-phosphate isomerase
KM410_26575	COG2190	(PTS) system
KM410_26580	COG2259	Doxx family
KM410_26585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM410_26600	COG0009	L-threonylcarbamoyladenylate synthase
KM410_26615	COG2890	protein-(glutamine-N5) methyltransferase activity
KM410_26635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM410_26640	COG1494	fructose-1,6-bisphosphatase
KM410_26660	COG4821	SIS domain
KM410_26670	COG3343	RNA polymerase activity
KM410_26680	COG1960	acyl-CoA dehydrogenase activity
KM410_26685	COG1960	acyl-CoA dehydrogenase activity
KM410_26690	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM410_26695	COG0183	Belongs to the thiolase family
KM410_26700	COG2181	nitrate reductase activity
KM410_26700	COG0247	lactate metabolic process
KM410_26705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM410_26715	COG3300	MHYT domain
KM410_26715	COG5001	Diguanylate cyclase
KM410_26735	COG2197	response regulator
KM410_26740	COG4585	Histidine kinase
KM410_26745	COG0842	Transport permease protein
KM410_26750	COG1131	(ABC) transporter
KM410_26755	COG0024	Methionine aminopeptidase
KM410_26765	COG2234	aminopeptidase activity
KM410_26785	COG1595	DNA-templated transcription, initiation
KM410_26790	COG0018	arginyl-trna synthetase
KM410_26795	COG4506	Protein conserved in bacteria
KM410_26800	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM410_26815	COG0010	Belongs to the arginase family
KM410_26825	COG2814	Major facilitator Superfamily
KM410_26830	COG0789	Transcriptional regulator
KM410_26835	COG0584	glycerophosphoryl diester phosphodiesterase
KM410_26840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM410_26850	COG1994	Peptidase M50
KM410_26860	COG1078	dGTPase activity
KM410_26865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM410_26870	COG1120	ATPase activity
KM410_26875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM410_26900	COG0095	Lipoate-protein ligase
KM410_26905	COG0280	phosphate acetyltransferase
KM410_26920	COG3773	Cell wall hydrolase
KM410_26930	COG2363	Small membrane protein
KM410_26940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM410_26945	COG2233	PERMEase
KM410_26950	COG0561	phosphatase activity
KM410_26955	COG2814	Major facilitator Superfamily
KM410_26965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM410_26970	COG1131	(ABC) transporter
KM410_26975	COG2755	lipolytic protein G-D-S-L family
KM410_26980	COG1609	Transcriptional regulator
KM410_26990	COG0460	homoserine dehydrogenase
KM410_27000	COG2873	o-acetylhomoserine
KM410_27010	COG1011	Hydrolase
KM410_27015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM410_27025	COG2197	response regulator
KM410_27035	COG0351	phosphomethylpyrimidine kinase
KM410_27040	COG3706	GGDEF domain
KM410_27045	COG2879	small protein
KM410_27050	COG1966	Carbon starvation protein
KM410_27055	COG3279	Response regulator of the LytR AlgR family
KM410_27060	COG0477	Major facilitator Superfamily
KM410_27085	COG0840	transmembrane signaling receptor activity
KM410_27095	COG1607	acyl-coa hydrolase
KM410_27110	COG0488	(ABC) transporter
KM410_27130	COG0463	Glycosyl transferase, family 2
KM410_27135	COG1309	transcriptional regulator
KM410_27140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM410_27145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM410_27145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM410_27150	COG0628	permease
KM410_27165	COG3279	Response regulator of the LytR AlgR family
KM410_27170	COG3275	phosphorelay sensor kinase activity
KM410_27175	COG2814	Major facilitator Superfamily
KM410_27180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM410_27185	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM410_27190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM410_27210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM410_27215	COG1272	protein, Hemolysin III
KM410_27235	COG0516	GMP reductase activity
KM410_27240	COG1164	Oligoendopeptidase f
KM410_27260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM410_27265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM410_27270	COG4853	Protein conserved in bacteria
KM410_27275	COG4863	YycH protein
KM410_27280	COG5002	protein histidine kinase activity
KM410_27285	COG0745	RESPONSE REGULATOR receiver
KM410_27315	COG0305	Participates in initiation and elongation during chromosome replication
KM410_27325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM410_27330	COG4241	membrane
KM410_27340	COG0629	single-stranded DNA binding
KM410_27350	COG0012	GTP binding
KM410_27355	COG4481	Protein conserved in bacteria
KM410_27360	COG0668	transmembrane transport
KM410_27370	COG1475	DNA binding
KM410_27375	COG1192	Involved in chromosome partitioning
KM410_27400	COG1847	R3H domain protein
KM410_27405	COG0706	membrane insertase activity
KM410_27415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM410_27470	COG3344	reverse transcriptase
KM410_27550	COG3344	reverse transcriptase
KM410_27745	COG4962	Type ii secretion system protein e
KM410_27880	COG2311	Membrane
KM410_27900	COG4196	transglutaminase domain protein
KM410_27905	COG0671	phosphoesterase, PA-phosphatase related
KM410_27920	COG1215	transferase activity, transferring glycosyl groups
KM410_27925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM410_27930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM410_28095	COG2002	toxin-antitoxin pair type II binding
KM410_28105	COG4974	Belongs to the 'phage' integrase family
KM410_28160	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM410_28170	COG4974	Belongs to the 'phage' integrase family
KM410_28195	COG0457	Tetratricopeptide repeat
KM410_28400	COG0791	NLP P60 protein
KM410_28400	COG0741	lytic transglycosylase activity
KM410_28465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM410_28525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM410_28535	COG4166	transmembrane transport
KM410_28570	COG1280	lysine exporter protein (LysE YggA)
KM410_28595	COG0681	Belongs to the peptidase S26 family
KM410_28670	COG1309	transcriptional regulator
KM410_28675	COG1683	Conserved Protein
KM410_28720	COG1192	Involved in chromosome partitioning