locus-tag	class	description
KM392_00010	COG0592	DNA-directed DNA polymerase activity
KM392_00015	COG2501	S4 domain
KM392_00025	COG0187	DNA topoisomerase II activity
KM392_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM392_00065	COG0516	GMP reductase activity
KM392_00065	COG0517	IMP dehydrogenase activity
KM392_00070	COG1686	Belongs to the peptidase S11 family
KM392_00100	COG1428	Deoxynucleoside kinase
KM392_00105	COG1428	Deoxynucleoside kinase
KM392_00110	COG1335	isochorismatase
KM392_00115	COG0590	tRNA wobble adenosine to inosine editing
KM392_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM392_00180	COG1982	Orn Lys Arg decarboxylase major
KM392_00190	COG0470	DNA polymerase III
KM392_00195	COG1774	PSP1 C-terminal conserved region
KM392_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM392_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM392_00220	COG2002	toxin-antitoxin pair type II binding
KM392_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM392_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM392_00230	COG0084	hydrolase, TatD family'
KM392_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM392_00250	COG4466	Protein conserved in bacteria
KM392_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM392_00270	COG0251	oxidation-reduction process
KM392_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM392_00305	COG2002	toxin-antitoxin pair type II binding
KM392_00310	COG2244	polysaccharide biosynthetic process
KM392_00315	COG3956	TIGRFAM MazG family protein
KM392_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM392_00340	COG1098	S1 RNA binding domain
KM392_00355	COG2208	phosphoserine phosphatase activity
KM392_00360	COG0037	tRNA processing
KM392_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM392_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM392_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM392_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM392_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM392_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM392_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM392_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM392_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM392_00420	COG1396	sequence-specific DNA binding
KM392_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM392_00455	COG3880	PFAM UvrB UvrC protein
KM392_00465	COG0542	response to heat
KM392_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM392_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM392_00500	COG1045	serine acetyltransferase
KM392_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM392_00520	COG3688	RNA-binding protein containing a PIN domain
KM392_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM392_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM392_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM392_00565	COG2813	Specifically methylates the guanine in position
KM392_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM392_00580	COG1358	cellular component organization or biogenesis
KM392_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM392_00710	COG0201	protein transport
KM392_00720	COG0024	Methionine aminopeptidase
KM392_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM392_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM392_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM392_00795	COG0489	protein tyrosine kinase activity
KM392_00805	COG2194	sulfuric ester hydrolase activity
KM392_00810	COG0726	polysaccharide deacetylase
KM392_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM392_00895	COG4856	YbbR-like protein
KM392_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM392_00915	COG0596	Alpha beta hydrolase
KM392_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM392_00940	COG4946	Tricorn protease homolog
KM392_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM392_00940	COG1506	peptidase
KM392_00975	COG2011	ABC-type metal ion transport system permease component
KM392_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM392_00985	COG1464	Belongs to the NlpA lipoprotein family
KM392_00990	COG0604	alcohol dehydrogenase
KM392_01005	COG2271	Major facilitator Superfamily
KM392_01015	COG2814	Major facilitator Superfamily
KM392_01030	COG0601	transmembrane transport
KM392_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM392_01040	COG0444	Belongs to the ABC transporter superfamily
KM392_01045	COG4608	Belongs to the ABC transporter superfamily
KM392_01050	COG4166	transmembrane transport
KM392_01060	COG2207	Transcriptional regulator
KM392_01075	COG4166	transmembrane transport
KM392_01080	COG4166	transmembrane transport
KM392_01085	COG0656	L-ascorbic acid biosynthetic process
KM392_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM392_01105	COG4149	molybdate abc transporter
KM392_01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM392_01115	COG1910	domain protein
KM392_01125	COG0583	DNA-binding transcription factor activity
KM392_01130	COG0697	spore germination
KM392_01145	COG0204	Acyl-transferase
KM392_01155	COG1609	Transcriptional regulator
KM392_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_01175	COG0084	hydrolase, TatD family'
KM392_01180	COG5298	Protein conserved in bacteria
KM392_01205	COG0488	(ABC) transporter
KM392_01220	COG0747	negative chemotaxis
KM392_01225	COG0601	transmembrane transport
KM392_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM392_01235	COG0444	Belongs to the ABC transporter superfamily
KM392_01240	COG4608	Belongs to the ABC transporter superfamily
KM392_01265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM392_01270	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM392_01280	COG2814	Major facilitator Superfamily
KM392_01290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM392_01300	COG4294	response to UV
KM392_01305	COG0457	Tetratricopeptide repeat
KM392_01305	COG0705	Rhomboid family
KM392_01315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM392_01320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM392_01325	COG0864	Transcriptional regulator
KM392_01330	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM392_01335	COG2183	response to ionizing radiation
KM392_01430	COG0802	atpase or kinase
KM392_01435	COG1214	PFAM Peptidase M22, glycoprotease
KM392_01440	COG0456	acetyltransferase
KM392_01450	COG0488	(ABC) transporter
KM392_01465	COG1266	CAAX protease self-immunity
KM392_01485	COG2252	PERMEase
KM392_01495	COG5002	protein histidine kinase activity
KM392_01515	COG1968	undecaprenyl-diphosphatase activity
KM392_01530	COG2205	protein histidine kinase activity
KM392_01535	COG0745	RESPONSE REGULATOR receiver
KM392_01555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM392_01560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM392_01565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM392_01575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM392_01590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM392_01600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM392_01610	COG0151	Belongs to the GarS family
KM392_01635	COG0210	DNA helicase
KM392_01645	COG4851	CamS sex pheromone cAM373 precursor
KM392_01665	COG1335	isochorismatase
KM392_01670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM392_01675	COG2011	ABC-type metal ion transport system permease component
KM392_01680	COG1464	Belongs to the NlpA lipoprotein family
KM392_01700	COG1846	Transcriptional regulator
KM392_01725	COG1597	lipid kinase activity
KM392_01730	COG0546	phosphoglycolate phosphatase activity
KM392_01735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM392_01745	COG1012	belongs to the aldehyde dehydrogenase family
KM392_01750	COG2076	Multidrug Resistance protein
KM392_01755	COG2309	aminopeptidase activity
KM392_01770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_01775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM392_01780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM392_01790	COG4807	Protein conserved in bacteria
KM392_01815	COG1757	Na H antiporter
KM392_01820	COG1473	amidohydrolase
KM392_01835	COG0450	alkyl hydroperoxide reductase
KM392_01855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_01860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_01865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_01880	COG0166	Belongs to the GPI family
KM392_01915	COG5002	protein histidine kinase activity
KM392_01935	COG3541	Predicted nucleotidyltransferase
KM392_01940	COG2814	Major facilitator Superfamily
KM392_01945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM392_01945	COG0723	plastoquinol--plastocyanin reductase activity
KM392_01955	COG0765	amino acid transport
KM392_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM392_01970	COG0840	transmembrane signaling receptor activity
KM392_01975	COG0840	transmembrane signaling receptor activity
KM392_01980	COG0366	Alpha amylase catalytic
KM392_01985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_01985	COG1263	PTS System
KM392_01985	COG2190	(PTS) system
KM392_02015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM392_02030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM392_02040	COG1116	anion transmembrane transporter activity
KM392_02045	COG0488	(ABC) transporter
KM392_02090	COG2270	Major facilitator Superfamily
KM392_02105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM392_02120	COG2310	stress, protein
KM392_02125	COG2310	stress, protein
KM392_02130	COG2310	stress, protein
KM392_02135	COG0861	Integral membrane protein TerC family
KM392_02145	COG3853	Toxic anion resistance protein (TelA)
KM392_02160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM392_02170	COG1295	ribonuclease BN
KM392_02175	COG2217	Heavy metal translocating P-type atpase
KM392_02180	COG0697	spore germination
KM392_02200	COG0586	Pfam SNARE associated Golgi protein
KM392_02215	COG3871	stress protein (general stress protein 26)
KM392_02220	COG0387	Pfam Sodium calcium exchanger
KM392_02230	COG0535	radical SAM domain protein
KM392_02255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM392_02260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM392_02265	COG0582	viral genome integration into host DNA
KM392_02275	COG1396	sequence-specific DNA binding
KM392_02290	COG1396	sequence-specific DNA binding
KM392_02325	COG1484	DNA-dependent DNA replication
KM392_02555	COG0101	tRNA pseudouridine synthase activity
KM392_02565	COG3829	transcription factor binding
KM392_02575	COG0833	amino acid
KM392_02580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM392_02610	COG1263	PTS System
KM392_02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_02615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM392_02630	COG0463	Glycosyl transferase, family 2
KM392_02645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM392_02645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM392_02665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM392_02685	COG1228	amidohydrolase
KM392_02690	COG1090	epimerase
KM392_02720	COG1988	membrane-bound metal-dependent
KM392_02725	COG1194	a g-specific adenine glycosylase
KM392_02750	COG1132	(ABC) transporter
KM392_02755	COG4129	membrane
KM392_02760	COG0070	glutamate synthase
KM392_02760	COG0069	glutamate synthase activity
KM392_02760	COG0067	glutamate synthase
KM392_02770	COG4555	ABC transporter
KM392_02790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM392_02795	COG0735	belongs to the Fur family
KM392_02910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM392_02915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM392_02925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM392_02935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM392_02945	COG2766	serine protein kinase
KM392_02965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM392_02975	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM392_02980	COG2268	Band 7 protein
KM392_02990	COG3290	protein histidine kinase activity
KM392_02995	COG4565	transcriptional regulatory protein
KM392_03000	COG2851	Citrate transporter
KM392_03020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM392_03025	COG3842	ATPase activity
KM392_03030	COG1175	transmembrane transport
KM392_03035	COG0395	ABC-type sugar transport system, permease component
KM392_03045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM392_03050	COG0745	RESPONSE REGULATOR receiver
KM392_03055	COG5002	protein histidine kinase activity
KM392_03065	COG4990	cell redox homeostasis
KM392_03075	COG3290	protein histidine kinase activity
KM392_03080	COG4565	transcriptional regulatory protein
KM392_03085	COG3493	citrate carrier protein
KM392_03090	COG0281	malic enzyme
KM392_03105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_03115	COG5002	protein histidine kinase activity
KM392_03120	COG0745	RESPONSE REGULATOR receiver
KM392_03125	COG0454	-acetyltransferase
KM392_03125	COG0456	acetyltransferase
KM392_03130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM392_03135	COG3383	formate dehydrogenase (NAD+) activity
KM392_03140	COG2427	Protein of unknown function (DUF1641)
KM392_03155	COG0531	amino acid
KM392_03160	COG0640	Transcriptional regulator
KM392_03165	COG2217	Heavy metal translocating P-type atpase
KM392_03170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM392_03185	COG3227	Zinc metalloprotease (Elastase)
KM392_03205	COG2720	vancomycin resistance protein
KM392_03210	COG1316	TRANSCRIPTIONal
KM392_03215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_03220	COG0346	lactoylglutathione lyase activity
KM392_03225	COG1253	flavin adenine dinucleotide binding
KM392_03230	COG1027	Aspartate ammonia-lyase
KM392_03235	COG1620	l-lactate permease
KM392_03250	COG3104	oligopeptide transport
KM392_03255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_03275	COG2226	methyltransferase
KM392_03280	COG0156	8-amino-7-oxononanoate synthase activity
KM392_03285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM392_03295	COG4548	von Willebrand factor, type A
KM392_03300	COG0714	Associated with various cellular activities
KM392_03305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM392_03325	COG0531	amino acid
KM392_03330	COG2188	Transcriptional regulator
KM392_03335	COG1263	PTS System
KM392_03335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_03340	COG0366	Alpha amylase catalytic
KM392_03355	COG0697	spore germination
KM392_03365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM392_03370	COG1115	amino acid carrier protein
KM392_03375	COG1126	abc transporter atp-binding protein
KM392_03380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM392_03385	COG0765	amino acid transport
KM392_03390	COG0765	amino acid transport
KM392_03395	COG0833	amino acid
KM392_03420	COG2378	regulation of single-species biofilm formation
KM392_03425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM392_03430	COG5002	protein histidine kinase activity
KM392_03445	COG0659	secondary active sulfate transmembrane transporter activity
KM392_03460	COG0747	negative chemotaxis
KM392_03470	COG0601	transmembrane transport
KM392_03475	COG4608	Belongs to the ABC transporter superfamily
KM392_03485	COG2271	Major facilitator Superfamily
KM392_03490	COG1846	Transcriptional regulator
KM392_03500	COG1609	Transcriptional regulator
KM392_03505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM392_03520	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM392_03525	COG1879	ABC-type sugar transport system periplasmic component
KM392_03550	COG1063	alcohol dehydrogenase
KM392_03565	COG3568	Endonuclease Exonuclease Phosphatase
KM392_03590	COG1968	undecaprenyl-diphosphatase activity
KM392_03595	COG0840	transmembrane signaling receptor activity
KM392_03600	COG1388	LysM domain
KM392_03600	COG3584	3D domain protein
KM392_03605	COG1476	TRANSCRIPTIONal
KM392_03620	COG3104	oligopeptide transport
KM392_03625	COG1114	Component of the transport system for branched-chain amino acids
KM392_03640	COG1113	amino acid transport
KM392_03645	COG2252	PERMEase
KM392_03670	COG0475	glutathione-regulated potassium exporter activity
KM392_03670	COG0569	domain protein
KM392_03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM392_03690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM392_03695	COG0833	amino acid
KM392_03700	COG4990	cell redox homeostasis
KM392_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM392_03720	COG0697	spore germination
KM392_03725	COG0531	amino acid
KM392_03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM392_03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM392_03745	COG1918	ferrous iron import across plasma membrane
KM392_03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM392_03750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM392_03755	COG0573	inorganic phosphate transmembrane transporter activity
KM392_03760	COG0581	inorganic phosphate transmembrane transporter activity
KM392_03770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM392_03890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM392_03910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM392_03915	COG1116	anion transmembrane transporter activity
KM392_03920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM392_03925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM392_03930	COG0352	thiamine-phosphate diphosphorylase activity
KM392_03935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM392_03940	COG2104	thiamine diphosphate biosynthetic process
KM392_03950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM392_03955	COG0351	phosphomethylpyrimidine kinase
KM392_03995	COG2205	protein histidine kinase activity
KM392_04000	COG2814	Major facilitator Superfamily
KM392_04005	COG1846	Transcriptional regulator
KM392_04020	COG2252	PERMEase
KM392_04025	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_04030	COG1376	ErfK ybiS ycfS ynhG family protein
KM392_04040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM392_04045	COG1621	beta-fructofuranosidase activity
KM392_04050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_04050	COG1263	PTS System
KM392_04055	COG1609	Transcriptional regulator
KM392_04065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM392_04105	COG0778	Nitroreductase
KM392_04110	COG2719	SpoVR family
KM392_04135	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM392_04140	COG1937	Protein conserved in bacteria
KM392_04145	COG0425	Belongs to the sulfur carrier protein TusA family
KM392_04145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_04150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_04155	COG0425	Belongs to the sulfur carrier protein TusA family
KM392_04160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_04170	COG2210	Belongs to the sulfur carrier protein TusA family
KM392_04175	COG0730	response to heat
KM392_04185	COG1316	TRANSCRIPTIONal
KM392_04190	COG0604	alcohol dehydrogenase
KM392_04195	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM392_04210	COG3711	transcriptional antiterminator
KM392_04210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM392_04215	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM392_04220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM392_04240	COG3584	3D domain protein
KM392_04240	COG1388	LysM domain
KM392_04245	COG0577	efflux transmembrane transporter activity
KM392_04250	COG1136	(ABC) transporter
KM392_04260	COG5522	Integral membrane protein (intg_mem_TP0381)
KM392_04275	COG1114	Component of the transport system for branched-chain amino acids
KM392_04280	COG3546	catalase activity
KM392_04315	COG0586	Pfam SNARE associated Golgi protein
KM392_04350	COG0531	amino acid
KM392_04355	COG0475	glutathione-regulated potassium exporter activity
KM392_04365	COG1737	Transcriptional regulator
KM392_04375	COG1263	PTS System
KM392_04375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_04385	COG2259	Doxx family
KM392_04400	COG0697	spore germination
KM392_04405	COG1522	sequence-specific DNA binding
KM392_04420	COG2076	Multidrug Resistance protein
KM392_04425	COG1309	transcriptional regulator
KM392_04430	COG2814	Major facilitator Superfamily
KM392_04435	COG1733	regulation of RNA biosynthetic process
KM392_04445	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM392_04450	COG4533	DNA binding
KM392_04455	COG2814	Major facilitator Superfamily
KM392_04465	COG0693	protein deglycase activity
KM392_04470	COG0693	protein deglycase activity
KM392_04470	COG0753	catalase activity
KM392_04480	COG0531	amino acid
KM392_04485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM392_04495	COG1012	belongs to the aldehyde dehydrogenase family
KM392_04500	COG1132	(ABC) transporter
KM392_04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM392_04515	COG0765	amino acid transport
KM392_04520	COG1126	abc transporter atp-binding protein
KM392_04535	COG0189	ligase activity
KM392_04565	COG0028	Belongs to the TPP enzyme family
KM392_04570	COG3527	Alpha-acetolactate decarboxylase
KM392_04585	COG0561	phosphatase activity
KM392_04600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM392_04615	COG0659	secondary active sulfate transmembrane transporter activity
KM392_04635	COG0653	protein targeting
KM392_04640	COG2244	polysaccharide biosynthetic process
KM392_04650	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM392_04655	COG4196	transglutaminase domain protein
KM392_04670	COG1696	Membrane protein involved in D-alanine export
KM392_04685	COG1024	Enoyl-CoA hydratase
KM392_04700	COG1363	Peptidase, m42
KM392_04720	COG3938	Belongs to the proline racemase family
KM392_04765	COG0601	transmembrane transport
KM392_04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM392_04780	COG4608	Belongs to the ABC transporter superfamily
KM392_04785	COG0322	excinuclease ABC activity
KM392_04815	COG0477	Major facilitator Superfamily
KM392_04820	COG3290	protein histidine kinase activity
KM392_04825	COG4565	transcriptional regulatory protein
KM392_04830	COG3181	Tripartite tricarboxylate transporter family receptor
KM392_04860	COG4978	Transcriptional regulator
KM392_04860	COG0789	Transcriptional regulator
KM392_04875	COG0305	Participates in initiation and elongation during chromosome replication
KM392_04915	COG0477	Major facilitator Superfamily
KM392_04965	COG1309	transcriptional regulator
KM392_04985	COG1183	phosphatidylcholine synthase activity
KM392_05005	COG2376	Dihydroxyacetone kinase
KM392_05015	COG2376	Dihydroxyacetone kinase
KM392_05020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM392_05025	COG1959	2 iron, 2 sulfur cluster binding
KM392_05055	COG2770	Histidine kinase
KM392_05055	COG3437	response regulator, receiver
KM392_05105	COG3237	CsbD-like
KM392_05130	COG1191	sigma factor activity
KM392_05140	COG2208	phosphoserine phosphatase activity
KM392_05145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM392_05150	COG0784	Response regulator, receiver
KM392_05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM392_05150	COG2198	Histidine kinase
KM392_05150	COG2205	protein histidine kinase activity
KM392_05205	COG0420	3'-5' exonuclease activity
KM392_05210	COG4717	serine-type aminopeptidase activity
KM392_05230	COG1309	transcriptional regulator
KM392_05235	COG2814	Major facilitator Superfamily
KM392_05240	COG0346	lactoylglutathione lyase activity
KM392_05245	COG0346	lactoylglutathione lyase activity
KM392_05250	COG0457	Tetratricopeptide repeat
KM392_05255	COG2267	carboxylic ester hydrolase activity
KM392_05275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM392_05280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM392_05290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM392_05330	COG0477	Major facilitator Superfamily
KM392_05335	COG0477	Major facilitator Superfamily
KM392_05345	COG3973	AAA domain
KM392_05350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM392_05370	COG4980	gas vesicle protein
KM392_05375	COG0537	adenosine 5'-monophosphoramidase activity
KM392_05380	COG1131	(ABC) transporter
KM392_05385	COG4473	ABC transporter
KM392_05400	COG1309	transcriptional regulator
KM392_05410	COG3402	PFAM membrane-flanked domain
KM392_05455	COG3402	PFAM membrane-flanked domain
KM392_05460	COG3428	Bacterial PH domain
KM392_05465	COG2329	Antibiotic biosynthesis monooxygenase
KM392_05470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM392_05475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM392_05480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM392_05485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM392_05520	COG1309	transcriptional regulator
KM392_05525	COG1511	domain protein
KM392_05550	COG1609	Transcriptional regulator
KM392_05560	COG1234	tRNA 3'-trailer cleavage
KM392_05565	COG0095	Lipoate-protein ligase
KM392_05575	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_05605	COG3209	COG3209 Rhs family protein
KM392_05645	COG1078	dGTPase activity
KM392_05655	COG1595	DNA-templated transcription, initiation
KM392_05660	COG2207	Transcriptional regulator
KM392_05660	COG3708	Transcriptional regulator
KM392_05675	COG2205	protein histidine kinase activity
KM392_05680	COG0745	RESPONSE REGULATOR receiver
KM392_05705	COG0501	Belongs to the peptidase M48B family
KM392_05710	COG0840	transmembrane signaling receptor activity
KM392_05715	COG0697	spore germination
KM392_05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM392_05740	COG2224	Isocitrate lyase
KM392_05765	COG4903	ComK protein
KM392_05770	COG0398	Pfam SNARE associated Golgi protein
KM392_05780	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM392_05785	COG1074	ATP-dependent DNA helicase activity
KM392_05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM392_05855	COG0367	asparagine synthase
KM392_05860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM392_05865	COG0753	catalase activity
KM392_05870	COG0004	ammonium transporteR
KM392_05890	COG2996	Protein conserved in bacteria
KM392_05900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM392_05925	COG0561	phosphatase activity
KM392_05935	COG0542	response to heat
KM392_05945	COG2267	carboxylic ester hydrolase activity
KM392_05960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_05965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM392_05970	COG5504	Zn-dependent protease
KM392_05980	COG0180	Tryptophanyl-tRNA synthetase
KM392_05990	COG4166	transmembrane transport
KM392_05995	COG0601	transmembrane transport
KM392_06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM392_06005	COG0444	Belongs to the ABC transporter superfamily
KM392_06010	COG4608	Belongs to the ABC transporter superfamily
KM392_06015	COG0534	Mate efflux family protein
KM392_06020	COG4166	transmembrane transport
KM392_06035	COG0861	Integral membrane protein TerC family
KM392_06040	COG4862	establishment of competence for transformation
KM392_06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM392_06055	COG1164	Oligoendopeptidase f
KM392_06065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM392_06070	COG2346	COG2346, Truncated hemoglobins
KM392_06075	COG4116	CYTH
KM392_06085	COG2357	RelA SpoT domain protein
KM392_06095	COG0564	pseudouridine synthase activity
KM392_06115	COG0463	Glycosyl transferase, family 2
KM392_06115	COG1216	Glycosyl transferase, family 2
KM392_06135	COG0463	Glycosyl transferase, family 2
KM392_06135	COG0457	Tetratricopeptide repeat
KM392_06155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM392_06170	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM392_06215	COG2153	protein acetylation
KM392_06225	COG2382	esterase
KM392_06240	COG5492	domain, Protein
KM392_06245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM392_06255	COG0512	Glutamine amidotransferase of anthranilate synthase
KM392_06255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM392_06290	COG1620	l-lactate permease
KM392_06295	COG5634	Uncharacterized conserved protein (DUF2278)
KM392_06350	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM392_06360	COG1476	TRANSCRIPTIONal
KM392_06420	COG2226	methyltransferase
KM392_06430	COG1686	Belongs to the peptidase S11 family
KM392_06435	COG0681	Belongs to the peptidase S26 family
KM392_06470	COG1012	belongs to the aldehyde dehydrogenase family
KM392_06475	COG3842	ATPase activity
KM392_06480	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM392_06485	COG1177	transmembrane transport
KM392_06490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM392_06500	COG2409	Drug exporters of the RND superfamily
KM392_06510	COG0564	pseudouridine synthase activity
KM392_06520	COG2340	Cysteine-rich secretory protein family
KM392_06525	COG0247	lactate metabolic process
KM392_06530	COG0277	FAD linked oxidase domain protein
KM392_06535	COG3835	regulator
KM392_06545	COG0745	RESPONSE REGULATOR receiver
KM392_06550	COG5002	protein histidine kinase activity
KM392_06555	COG2186	Transcriptional regulator
KM392_06575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM392_06585	COG2116	formate transmembrane transporter activity
KM392_06590	COG0861	Integral membrane protein TerC family
KM392_06605	COG2030	dehydratase
KM392_06625	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_06630	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM392_06635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM392_06640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM392_06655	COG1840	ABC-type Fe3 transport system, periplasmic component
KM392_06685	COG1349	DNA-binding transcription factor activity
KM392_06705	COG2861	carbohydrate metabolic process
KM392_06715	COG3852	Histidine kinase
KM392_06720	COG1846	Transcriptional regulator
KM392_06730	COG2318	DinB family
KM392_06735	COG5002	protein histidine kinase activity
KM392_06745	COG0720	synthase
KM392_06760	COG4873	Protein conserved in bacteria
KM392_06790	COG1780	Probably involved in ribonucleotide reductase function
KM392_06810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM392_06815	COG1725	Transcriptional regulator
KM392_06820	COG1131	(ABC) transporter
KM392_06830	COG1131	(ABC) transporter
KM392_06835	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM392_06850	COG1522	sequence-specific DNA binding
KM392_06860	COG1335	isochorismatase
KM392_06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM392_06875	COG2070	2-Nitropropane dioxygenase
KM392_06880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM392_06890	COG1696	Membrane protein involved in D-alanine export
KM392_06915	COG0716	FMN binding
KM392_06930	COG3173	Aminoglycoside phosphotransferase
KM392_06950	COG0534	Mate efflux family protein
KM392_06955	COG1968	undecaprenyl-diphosphatase activity
KM392_06970	COG1846	Transcriptional regulator
KM392_06980	COG1301	dicarboxylic acid transport
KM392_06985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM392_06990	COG4709	membrane
KM392_06995	COG3874	Sporulation protein YtfJ
KM392_07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM392_07025	COG0028	Belongs to the TPP enzyme family
KM392_07030	COG0440	acetolactate synthase activity
KM392_07035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM392_07045	COG0473	3-isopropylmalate dehydrogenase activity
KM392_07070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM392_07105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM392_07120	COG1183	phosphatidylcholine synthase activity
KM392_07125	COG1368	sulfuric ester hydrolase activity
KM392_07135	COG0019	diaminopimelate decarboxylase activity
KM392_07155	COG0529	Catalyzes the synthesis of activated sulfate
KM392_07160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM392_07180	COG1648	precorrin-2 dehydrogenase activity
KM392_07185	COG0733	neurotransmitter:sodium symporter activity
KM392_07205	COG1757	Na H antiporter
KM392_07220	COG4758	membrane
KM392_07225	COG4585	Histidine kinase
KM392_07230	COG2197	response regulator
KM392_07240	COG1114	Component of the transport system for branched-chain amino acids
KM392_07250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM392_07275	COG1017	nitric oxide dioxygenase activity
KM392_07275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM392_07290	COG0730	response to heat
KM392_07295	COG0306	phosphate transporter
KM392_07300	COG1392	Phosphate transport regulator
KM392_07305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM392_07325	COG1801	Protein of unknown function DUF72
KM392_07335	COG0582	viral genome integration into host DNA
KM392_07340	COG5002	protein histidine kinase activity
KM392_07360	COG0392	lysyltransferase activity
KM392_07360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM392_07375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM392_07380	COG1686	Belongs to the peptidase S11 family
KM392_07385	COG2715	membrane protein required for spore maturation
KM392_07390	COG0700	Nucleoside recognition
KM392_07395	COG1187	pseudouridine synthase activity
KM392_07405	COG1333	cytochrome c biogenesis protein
KM392_07410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM392_07415	COG0745	RESPONSE REGULATOR receiver
KM392_07420	COG5002	protein histidine kinase activity
KM392_07425	COG2096	Adenosyltransferase
KM392_07440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM392_07445	COG1141	Ferredoxin
KM392_07450	COG4955	Helix-turn-helix domain
KM392_07455	COG0514	ATP-dependent DNA helicase (RecQ)
KM392_07460	COG1266	CAAX protease self-immunity
KM392_07480	COG4862	establishment of competence for transformation
KM392_07485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM392_07505	COG0492	ferredoxin-NADP+ reductase activity
KM392_07580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM392_07595	COG0142	geranyltranstransferase activity
KM392_07605	COG0142	geranyltranstransferase activity
KM392_07625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM392_07630	COG0457	Tetratricopeptide repeat
KM392_07650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM392_07660	COG4347	Protein of unknown function (DUF1405)
KM392_07675	COG2738	Putative neutral zinc metallopeptidase
KM392_07685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_07690	COG1694	Mazg nucleotide pyrophosphohydrolase
KM392_07705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM392_07710	COG0438	transferase activity, transferring glycosyl groups
KM392_07765	COG3935	DnaD domain protein
KM392_07770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM392_07780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM392_07780	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM392_07840	COG0116	Belongs to the methyltransferase superfamily
KM392_07850	COG1199	ATP-dependent helicase activity
KM392_07855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM392_07865	COG3173	Aminoglycoside phosphotransferase
KM392_07870	COG0024	Methionine aminopeptidase
KM392_07880	COG2233	PERMEase
KM392_07885	COG2311	Membrane
KM392_07890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM392_07900	COG0456	acetyltransferase
KM392_07950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM392_07975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM392_07990	COG1215	transferase activity, transferring glycosyl groups
KM392_08010	COG0454	-acetyltransferase
KM392_08030	COG0328	RNA-DNA hybrid ribonuclease activity
KM392_08070	COG1280	lysine exporter protein (LysE YggA)
KM392_08085	COG3162	membrane
KM392_08090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM392_08095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM392_08105	COG0475	glutathione-regulated potassium exporter activity
KM392_08110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM392_08115	COG0789	Transcriptional regulator
KM392_08115	COG4978	Transcriptional regulator
KM392_08125	COG2323	membrane
KM392_08130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM392_08185	COG1923	regulation of RNA biosynthetic process
KM392_08195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM392_08200	COG1360	Flagellar Motor Protein
KM392_08205	COG2201	protein-glutamate methylesterase activity
KM392_08210	COG2198	Histidine kinase
KM392_08210	COG0643	Histidine kinase
KM392_08215	COG0643	Histidine kinase
KM392_08215	COG2198	Histidine kinase
KM392_08220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM392_08220	COG1776	CheC inhibitor of MCP methylation
KM392_08235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM392_08255	COG1256	bacterial-type flagellum assembly
KM392_08280	COG1815	bacterial-type flagellum-dependent cell motility
KM392_08285	COG1558	bacterial-type flagellum-dependent cell motility
KM392_08300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM392_08310	COG1157	protein secretion by the type III secretion system
KM392_08350	COG0784	Response regulator, receiver
KM392_08350	COG0835	chemotaxis
KM392_08360	COG0463	Glycosyl transferase, family 2
KM392_08395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM392_08400	COG0741	lytic transglycosylase activity
KM392_08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM392_08415	COG1776	CheC inhibitor of MCP methylation
KM392_08425	COG1338	Plays a role in the flagellum-specific transport system
KM392_08430	COG1987	bacterial-type flagellum assembly
KM392_08440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM392_08445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM392_08450	COG1419	protein localization to endoplasmic reticulum
KM392_08455	COG4786	Flagellar basal body rod
KM392_08460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM392_08485	COG1309	transcriptional regulator
KM392_08505	COG2329	Antibiotic biosynthesis monooxygenase
KM392_08535	COG3842	ATPase activity
KM392_08540	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM392_08550	COG1234	tRNA 3'-trailer cleavage
KM392_08575	COG1686	Belongs to the peptidase S11 family
KM392_08615	COG0367	asparagine synthase
KM392_08645	COG1802	Transcriptional regulator
KM392_08650	COG0697	spore germination
KM392_08655	COG0523	cobalamin synthesis protein
KM392_08660	COG0701	Predicted permease
KM392_08670	COG1216	Glycosyl transferase, family 2
KM392_08670	COG0438	transferase activity, transferring glycosyl groups
KM392_08675	COG1757	Na H antiporter
KM392_08680	COG0114	fumarate hydratase activity
KM392_08705	COG3340	Belongs to the peptidase S51 family
KM392_08725	COG0785	Cytochrome C biogenesis protein
KM392_08755	COG2733	membrane
KM392_08790	COG1131	(ABC) transporter
KM392_08805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM392_08810	COG0528	UMP kinase activity
KM392_08820	COG1027	Aspartate ammonia-lyase
KM392_08825	COG0281	malic enzyme
KM392_08830	COG4191	Histidine kinase
KM392_08835	COG0784	Response regulator, receiver
KM392_08840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM392_08900	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM392_08910	COG2814	Major facilitator Superfamily
KM392_08925	COG1966	Carbon starvation protein
KM392_08935	COG0477	Major facilitator Superfamily
KM392_08940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_08950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM392_08980	COG2244	polysaccharide biosynthetic process
KM392_08985	COG0733	neurotransmitter:sodium symporter activity
KM392_08995	COG5566	PFAM Mor transcription activator
KM392_09000	COG2323	membrane
KM392_09015	COG2084	Dehydrogenase
KM392_09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM392_09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM392_09045	COG0028	Belongs to the TPP enzyme family
KM392_09050	COG0440	acetolactate synthase activity
KM392_09055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM392_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM392_09095	COG3384	dioxygenase
KM392_09105	COG3279	Response regulator of the LytR AlgR family
KM392_09110	COG0427	acetyl-CoA hydrolase
KM392_09130	COG1073	alpha beta
KM392_09135	COG4166	transmembrane transport
KM392_09160	COG0535	radical SAM domain protein
KM392_09165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_09185	COG1914	H( )-stimulated, divalent metal cation uptake system
KM392_09200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM392_09230	COG2390	Transcriptional regulator
KM392_09240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_09245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM392_09260	COG4224	UPF0291 protein
KM392_09280	COG0006	proline dipeptidase activity
KM392_09285	COG2132	Multicopper oxidase
KM392_09300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM392_09315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM392_09330	COG2372	response to copper ion
KM392_09330	COG1276	copper resistance
KM392_09335	COG4549	nuclear export factor GLE1
KM392_09345	COG0697	spore germination
KM392_09350	COG0583	DNA-binding transcription factor activity
KM392_09355	COG1959	2 iron, 2 sulfur cluster binding
KM392_09360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM392_09365	COG0778	Nitroreductase
KM392_09375	COG0628	permease
KM392_09385	COG1231	oxidoreductase activity
KM392_09390	COG0523	cobalamin synthesis protein
KM392_09405	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_09410	COG2030	dehydratase
KM392_09415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_09425	COG0411	ABC transporter
KM392_09445	COG0583	DNA-binding transcription factor activity
KM392_09455	COG1942	4-Oxalocrotonate Tautomerase
KM392_09465	COG1846	Transcriptional regulator
KM392_09475	COG1271	oxidase subunit
KM392_09480	COG1294	oxidase, subunit
KM392_09485	COG4988	ABC transporter
KM392_09490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM392_09510	COG1686	Belongs to the peptidase S11 family
KM392_09525	COG0791	NLP P60 protein
KM392_09525	COG1388	LysM domain
KM392_09540	COG0745	RESPONSE REGULATOR receiver
KM392_09555	COG0300	oxidoreductase activity
KM392_09590	COG0460	homoserine dehydrogenase
KM392_09615	COG1316	TRANSCRIPTIONal
KM392_09625	COG0745	RESPONSE REGULATOR receiver
KM392_09630	COG5002	protein histidine kinase activity
KM392_09645	COG1285	pathogenesis
KM392_09650	COG1247	-acetyltransferase
KM392_09670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM392_09680	COG1082	Xylose isomerase domain protein TIM barrel
KM392_09690	COG2814	Major facilitator Superfamily
KM392_09695	COG1279	arginine transmembrane transporter activity
KM392_09705	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM392_09740	COG0577	efflux transmembrane transporter activity
KM392_09745	COG2002	toxin-antitoxin pair type II binding
KM392_09750	COG1404	Belongs to the peptidase S8 family
KM392_09755	COG0640	Transcriptional regulator
KM392_09760	COG0667	Aldo Keto reductase
KM392_09765	COG2814	Major facilitator Superfamily
KM392_09790	COG0840	transmembrane signaling receptor activity
KM392_09805	COG3949	Membrane
KM392_09810	COG0783	Belongs to the Dps family
KM392_09825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM392_09835	COG1231	oxidoreductase activity
KM392_09845	COG4989	oxidoreductase activity
KM392_09850	COG0523	cobalamin synthesis protein
KM392_09855	COG0456	acetyltransferase
KM392_09910	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM392_09910	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM392_09920	COG0702	epimerase
KM392_09930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM392_09940	COG4166	transmembrane transport
KM392_09955	COG0406	alpha-ribazole phosphatase activity
KM392_09965	COG5337	Spore coat protein CotH
KM392_09970	COG1051	belongs to the nudix hydrolase family
KM392_09975	COG0586	Pfam SNARE associated Golgi protein
KM392_09980	COG2244	polysaccharide biosynthetic process
KM392_09990	COG0701	Predicted permease
KM392_09995	COG3689	TIGRFAM TIGR03943 family protein
KM392_10000	COG1607	acyl-coa hydrolase
KM392_10010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM392_10025	COG0702	epimerase
KM392_10030	COG2839	Protein conserved in bacteria
KM392_10035	COG1253	flavin adenine dinucleotide binding
KM392_10050	COG1114	Component of the transport system for branched-chain amino acids
KM392_10055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM392_10075	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM392_10085	COG1876	peptidase activity
KM392_10095	COG0154	amidase activity
KM392_10100	COG2211	Major facilitator Superfamily
KM392_10120	COG0561	phosphatase activity
KM392_10130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM392_10135	COG4106	trans-aconitate 2-methyltransferase activity
KM392_10150	COG1819	glycosyl
KM392_10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_10160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_10185	COG0456	acetyltransferase
KM392_10235	COG3874	Sporulation protein YtfJ
KM392_10285	COG0346	lactoylglutathione lyase activity
KM392_10295	COG0604	alcohol dehydrogenase
KM392_10300	COG1595	DNA-templated transcription, initiation
KM392_10325	COG0386	Belongs to the glutathione peroxidase family
KM392_10330	COG1305	Transglutaminase-like
KM392_10335	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM392_10340	COG0714	Associated with various cellular activities
KM392_10355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM392_10360	COG1140	nitrate reductase beta subunit
KM392_10365	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM392_10370	COG2181	nitrate reductase activity
KM392_10390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM392_10395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM392_10400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM392_10405	COG0303	'Molybdopterin
KM392_10410	COG0314	molybdopterin synthase activity
KM392_10420	COG2223	nitrite transmembrane transporter activity
KM392_10435	COG1648	precorrin-2 dehydrogenase activity
KM392_10445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM392_10445	COG1587	Uroporphyrinogen-III synthase
KM392_10450	COG2146	nitrite reductase [NAD(P)H] activity
KM392_10455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM392_10460	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM392_10495	COG2359	stage V sporulation protein S
KM392_10510	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM392_10525	COG1418	mRNA catabolic process
KM392_10530	COG0488	(ABC) transporter
KM392_10545	COG0629	single-stranded DNA binding
KM392_10565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM392_10575	COG1413	lyase activity
KM392_10590	COG2521	methyltransferase
KM392_10590	COG2136	Putative SAM-dependent methyltransferase
KM392_10595	COG0018	arginyl-trna synthetase
KM392_10620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM392_10640	COG0017	Asparaginyl-tRNA synthetase
KM392_10660	COG1674	ftsk spoiiie
KM392_10730	COG1929	Belongs to the glycerate kinase type-1 family
KM392_10735	COG0471	metal ion transport
KM392_10740	COG0745	RESPONSE REGULATOR receiver
KM392_10745	COG3850	Histidine kinase
KM392_10745	COG5002	protein histidine kinase activity
KM392_10760	COG0733	neurotransmitter:sodium symporter activity
KM392_10785	COG2610	gluconate transmembrane transporter activity
KM392_10790	COG1454	alcohol dehydrogenase
KM392_10795	COG1794	racemase activity, acting on amino acids and derivatives
KM392_10805	COG0456	acetyltransferase
KM392_10820	COG1131	(ABC) transporter
KM392_10835	COG0546	phosphoglycolate phosphatase activity
KM392_10855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM392_10870	COG0768	penicillin binding
KM392_10875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM392_10880	COG0204	Acyl-transferase
KM392_10885	COG1272	protein, Hemolysin III
KM392_10895	COG0805	protein transport
KM392_10905	COG1307	EDD domain protein, DegV family
KM392_10910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM392_10915	COG1999	signal sequence binding
KM392_10920	COG0071	Belongs to the small heat shock protein (HSP20) family
KM392_10925	COG0367	asparagine synthase
KM392_10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_10945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM392_10970	COG1051	belongs to the nudix hydrolase family
KM392_10980	COG0668	transmembrane transport
KM392_10985	COG2203	Gaf domain
KM392_10985	COG4585	Histidine kinase
KM392_10990	COG2197	response regulator
KM392_11000	COG1064	alcohol dehydrogenase
KM392_11025	COG1070	Carbohydrate kinase
KM392_11030	COG1070	Carbohydrate kinase
KM392_11060	COG0517	IMP dehydrogenase activity
KM392_11060	COG1125	glycine betaine transport
KM392_11065	COG1174	glycine betaine transport
KM392_11100	COG1253	flavin adenine dinucleotide binding
KM392_11105	COG1012	belongs to the aldehyde dehydrogenase family
KM392_11110	COG5506	Protein of unknown function (DUF1694)
KM392_11125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM392_11130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM392_11135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM392_11140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM392_11145	COG0456	acetyltransferase
KM392_11150	COG3829	transcription factor binding
KM392_11155	COG1509	lysine 2,3-aminomutase activity
KM392_11195	COG4326	sporulation control protein
KM392_11200	COG0671	phosphoesterase, PA-phosphatase related
KM392_11205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM392_11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM392_11240	COG1715	Restriction endonuclease
KM392_11240	COG1787	Restriction endonuclease
KM392_11330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM392_11370	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM392_11370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM392_11375	COG2814	Major facilitator Superfamily
KM392_11380	COG4841	protein insertion into membrane
KM392_11385	COG0372	Belongs to the citrate synthase family
KM392_11390	COG2079	MmgE PrpD family protein
KM392_11395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM392_11400	COG1960	acyl-CoA dehydrogenase activity
KM392_11405	COG2084	Dehydrogenase
KM392_11415	COG1280	lysine exporter protein (LysE YggA)
KM392_11420	COG1024	Enoyl-CoA hydratase
KM392_11435	COG0420	3'-5' exonuclease activity
KM392_11440	COG0419	ATPase involved in DNA repair
KM392_11465	COG2223	nitrite transmembrane transporter activity
KM392_11470	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_11475	COG1169	isochorismate synthase
KM392_11480	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM392_11485	COG3433	isochorismatase activity
KM392_11485	COG1535	isochorismatase
KM392_11495	COG3251	PFAM MbtH domain protein
KM392_11500	COG2814	Major facilitator Superfamily
KM392_11515	COG0776	regulation of translation
KM392_11525	COG2318	DinB family
KM392_11550	COG2329	Antibiotic biosynthesis monooxygenase
KM392_11555	COG1187	pseudouridine synthase activity
KM392_11560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM392_11575	COG0596	Alpha beta hydrolase
KM392_11580	COG2814	Major facilitator Superfamily
KM392_11605	COG2226	methyltransferase
KM392_11650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_11685	COG1247	-acetyltransferase
KM392_11715	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM392_11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_11735	COG1278	Cold shock
KM392_11750	COG0010	Belongs to the arginase family
KM392_11755	COG0561	phosphatase activity
KM392_11800	COG0583	DNA-binding transcription factor activity
KM392_11805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM392_11820	COG0583	DNA-binding transcription factor activity
KM392_11825	COG2258	MOSC domain
KM392_11840	COG1132	(ABC) transporter
KM392_11845	COG1132	(ABC) transporter
KM392_11865	COG1396	sequence-specific DNA binding
KM392_11890	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM392_11895	COG1595	DNA-templated transcription, initiation
KM392_11920	COG1649	PFAM Uncharacterised BCR, COG1649
KM392_11945	COG2971	BadF BadG BcrA BcrD
KM392_11950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM392_11955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM392_11975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_12005	COG1309	transcriptional regulator
KM392_12025	COG0577	efflux transmembrane transporter activity
KM392_12025	COG1136	(ABC) transporter
KM392_12030	COG0500	methyltransferase
KM392_12030	COG3615	Tellurite resistance protein tehB
KM392_12040	COG2226	methyltransferase
KM392_12045	COG3961	Belongs to the TPP enzyme family
KM392_12050	COG1846	Transcriptional regulator
KM392_12090	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM392_12105	COG1595	DNA-templated transcription, initiation
KM392_12115	COG0768	penicillin binding
KM392_12120	COG0768	penicillin binding
KM392_12125	COG2367	Beta-lactamase
KM392_12130	COG0671	phosphoesterase, PA-phosphatase related
KM392_12135	COG1609	Transcriptional regulator
KM392_12140	COG2814	Major facilitator Superfamily
KM392_12145	COG0673	inositol 2-dehydrogenase activity
KM392_12155	COG1012	belongs to the aldehyde dehydrogenase family
KM392_12170	COG0191	fructose-bisphosphate aldolase activity
KM392_12190	COG0737	Belongs to the 5'-nucleotidase family
KM392_12205	COG1476	TRANSCRIPTIONal
KM392_12220	COG1876	peptidase activity
KM392_12240	COG1309	transcriptional regulator
KM392_12245	COG0488	(ABC) transporter
KM392_12260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_12280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_12295	COG1131	(ABC) transporter
KM392_12305	COG1309	transcriptional regulator
KM392_12320	COG1960	acyl-CoA dehydrogenase activity
KM392_12325	COG0439	Biotin carboxylase
KM392_12330	COG0511	ligase activity, forming carbon-carbon bonds
KM392_12335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM392_12340	COG1024	Enoyl-CoA hydratase
KM392_12345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM392_12350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM392_12360	COG1247	-acetyltransferase
KM392_12365	COG0572	uridine kinase
KM392_12375	COG2318	DinB family
KM392_12380	COG1686	Belongs to the peptidase S11 family
KM392_12405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM392_12445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM392_12445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM392_12470	COG2814	Major facilitator Superfamily
KM392_12485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM392_12505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_12520	COG1063	alcohol dehydrogenase
KM392_12550	COG3773	Cell wall hydrolase
KM392_12560	COG0745	RESPONSE REGULATOR receiver
KM392_12575	COG0488	(ABC) transporter
KM392_12590	COG1136	(ABC) transporter
KM392_12615	COG0460	homoserine dehydrogenase
KM392_12620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_12630	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM392_12695	COG2124	cytochrome p450
KM392_12730	COG0561	phosphatase activity
KM392_12740	COG5002	protein histidine kinase activity
KM392_12745	COG0768	penicillin binding
KM392_12750	COG1819	glycosyl
KM392_12755	COG1794	racemase activity, acting on amino acids and derivatives
KM392_12765	COG1122	ATPase activity
KM392_12780	COG2205	protein histidine kinase activity
KM392_12790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM392_12795	COG0604	alcohol dehydrogenase
KM392_12800	COG0768	penicillin binding
KM392_12810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM392_12845	COG0693	protein deglycase activity
KM392_12875	COG2814	Major facilitator Superfamily
KM392_12890	COG0584	glycerophosphoryl diester phosphodiesterase
KM392_12910	COG0697	spore germination
KM392_12935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM392_12945	COG2223	nitrite transmembrane transporter activity
KM392_12960	COG2816	NAD+ diphosphatase activity
KM392_12965	COG0592	DNA-directed DNA polymerase activity
KM392_12970	COG1051	belongs to the nudix hydrolase family
KM392_13005	COG3878	Protein conserved in bacteria
KM392_13050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM392_13065	COG0322	excinuclease ABC activity
KM392_13110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM392_13135	COG1011	Hydrolase
KM392_13150	COG0657	acetylesterase activity
KM392_13155	COG0076	glutamate decarboxylase activity
KM392_13170	COG1523	belongs to the glycosyl hydrolase 13 family
KM392_13175	COG3227	Zinc metalloprotease (Elastase)
KM392_13195	COG0201	protein transport
KM392_13205	COG0697	spore germination
KM392_13210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_13240	COG4129	membrane
KM392_13245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_13260	COG2959	enzyme of heme biosynthesis
KM392_13280	COG3483	tryptophan 2,3-dioxygenase activity
KM392_13285	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM392_13290	COG3844	kynureninase activity
KM392_13295	COG1309	transcriptional regulator
KM392_13325	COG3284	Transcriptional regulator
KM392_13345	COG1349	DNA-binding transcription factor activity
KM392_13365	COG1959	2 iron, 2 sulfur cluster binding
KM392_13380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM392_13385	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM392_13390	COG0022	dehydrogenase e1 component
KM392_13395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM392_13405	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_13410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM392_13410	COG0456	acetyltransferase
KM392_13440	COG4176	ABC-type proline glycine betaine transport system permease component
KM392_13445	COG0517	IMP dehydrogenase activity
KM392_13445	COG4175	Glycine betaine
KM392_13470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM392_13475	COG2153	protein acetylation
KM392_13480	COG3397	chitin binding
KM392_13495	COG2205	protein histidine kinase activity
KM392_13520	COG2333	competence protein COMEC
KM392_13520	COG0658	competence protein
KM392_13570	COG3973	AAA domain
KM392_13585	COG2105	PFAM AIG2 family protein
KM392_13590	COG0514	ATP-dependent DNA helicase (RecQ)
KM392_13610	COG4637	Psort location Cytoplasmic, score
KM392_13635	COG3397	chitin binding
KM392_13650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM392_13655	COG1115	amino acid carrier protein
KM392_13660	COG1012	belongs to the aldehyde dehydrogenase family
KM392_13665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM392_13675	COG3938	Belongs to the proline racemase family
KM392_13680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM392_13720	COG0586	Pfam SNARE associated Golgi protein
KM392_13735	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM392_13740	COG0519	Catalyzes the synthesis of GMP from XMP
KM392_13745	COG4166	transmembrane transport
KM392_13755	COG4948	Mandelate Racemase Muconate Lactonizing
KM392_13800	COG2936	dipeptidyl-peptidase activity
KM392_13805	COG5002	protein histidine kinase activity
KM392_13810	COG0745	RESPONSE REGULATOR receiver
KM392_13845	COG1164	Oligoendopeptidase f
KM392_13860	COG1307	EDD domain protein, DegV family
KM392_13880	COG2814	Major facilitator Superfamily
KM392_13890	COG1664	Polymer-forming cytoskeletal
KM392_13895	COG0789	Transcriptional regulator
KM392_13900	COG4533	DNA binding
KM392_13905	COG0477	Major facilitator Superfamily
KM392_13905	COG2814	Major facilitator Superfamily
KM392_13925	COG2261	transglycosylase associated protein
KM392_13940	COG2226	methyltransferase
KM392_13975	COG0436	Aminotransferase
KM392_13980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM392_13985	COG5146	pantothenate kinase activity
KM392_14005	COG1131	(ABC) transporter
KM392_14050	COG0628	permease
KM392_14060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM392_14065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM392_14070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM392_14075	COG1116	anion transmembrane transporter activity
KM392_14095	COG2816	NAD+ diphosphatase activity
KM392_14115	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM392_14140	COG0697	spore germination
KM392_14145	COG2318	DinB family
KM392_14185	COG0861	Integral membrane protein TerC family
KM392_14190	COG1368	sulfuric ester hydrolase activity
KM392_14195	COG0488	(ABC) transporter
KM392_14210	COG1309	transcriptional regulator
KM392_14225	COG0287	Prephenate dehydrogenase
KM392_14230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM392_14235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM392_14240	COG1605	Chorismate mutase
KM392_14240	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM392_14275	COG1388	LysM domain
KM392_14275	COG3584	3D domain protein
KM392_14285	COG1595	DNA-templated transcription, initiation
KM392_14310	COG1879	ABC-type sugar transport system periplasmic component
KM392_14320	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM392_14330	COG2390	Transcriptional regulator
KM392_14335	COG1070	Carbohydrate kinase
KM392_14365	COG2329	Antibiotic biosynthesis monooxygenase
KM392_14385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_14395	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM392_14400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM392_14405	COG4187	Peptidase family M20/M25/M40
KM392_14410	COG1414	Transcriptional regulator
KM392_14415	COG0833	amino acid
KM392_14420	COG1690	Belongs to the RtcB family
KM392_14425	COG3239	Fatty acid desaturase
KM392_14430	COG1785	Belongs to the alkaline phosphatase family
KM392_14440	COG3655	Transcriptional regulator
KM392_14455	COG4377	Putative membrane peptidase family (DUF2324)
KM392_14465	COG3279	Response regulator of the LytR AlgR family
KM392_14475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_14480	COG0346	lactoylglutathione lyase activity
KM392_14500	COG0714	Associated with various cellular activities
KM392_14550	COG0463	Glycosyl transferase, family 2
KM392_14560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM392_14565	COG0753	catalase activity
KM392_14575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM392_14600	COG0714	Associated with various cellular activities
KM392_14610	COG0778	Nitroreductase
KM392_14615	COG1846	Transcriptional regulator
KM392_14650	COG1725	Transcriptional regulator
KM392_14660	COG1136	(ABC) transporter
KM392_14660	COG0577	efflux transmembrane transporter activity
KM392_14685	COG2207	Transcriptional regulator
KM392_14690	COG0456	acetyltransferase
KM392_14710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_14730	COG0642	Histidine kinase
KM392_14735	COG0745	RESPONSE REGULATOR receiver
KM392_14740	COG0596	Alpha beta hydrolase
KM392_14770	COG0730	response to heat
KM392_14780	COG0833	amino acid
KM392_14790	COG4335	DNA alkylation repair
KM392_14830	COG0768	penicillin binding
KM392_14840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM392_14870	COG1984	allophanate hydrolase subunit 2
KM392_14875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM392_14880	COG1414	Transcriptional regulator
KM392_14895	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM392_14900	COG0640	Transcriptional regulator
KM392_14910	COG1960	acyl-CoA dehydrogenase activity
KM392_14925	COG3314	Sporulation integral membrane protein YlbJ
KM392_14940	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM392_14955	COG0574	Belongs to the PEP-utilizing enzyme family
KM392_14955	COG3848	Pyruvate phosphate dikinase
KM392_14960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_14975	COG5577	PFAM Coat F domain
KM392_14980	COG3403	YqcI/YcgG family
KM392_14985	COG1280	lysine exporter protein (LysE YggA)
KM392_15020	COG1063	alcohol dehydrogenase
KM392_15035	COG1027	Aspartate ammonia-lyase
KM392_15040	COG0252	asparaginase activity
KM392_15045	COG1396	sequence-specific DNA binding
KM392_15055	COG0322	excinuclease ABC activity
KM392_15060	COG0531	amino acid
KM392_15065	COG1114	Component of the transport system for branched-chain amino acids
KM392_15070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM392_15080	COG0281	malic enzyme
KM392_15095	COG0531	amino acid
KM392_15105	COG0784	Response regulator, receiver
KM392_15115	COG2066	Belongs to the glutaminase family
KM392_15120	COG1115	amino acid carrier protein
KM392_15150	COG0737	Belongs to the 5'-nucleotidase family
KM392_15155	COG0753	catalase activity
KM392_15160	COG2267	carboxylic ester hydrolase activity
KM392_15165	COG1335	isochorismatase
KM392_15185	COG0583	DNA-binding transcription factor activity
KM392_15190	COG1846	Transcriptional regulator
KM392_15195	COG0598	Magnesium transport protein CorA
KM392_15230	COG0415	Belongs to the DNA photolyase family
KM392_15235	COG0288	reversible hydration of carbon dioxide
KM392_15245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM392_15250	COG5609	conserved protein (DUF2294)
KM392_15265	COG1575	Belongs to the MenA family. Type 1 subfamily
KM392_15270	COG2267	carboxylic ester hydrolase activity
KM392_15275	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM392_15280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM392_15285	COG1121	(ABC) transporter
KM392_15315	COG0798	PFAM Bile acid sodium symporter
KM392_15320	COG0346	lactoylglutathione lyase activity
KM392_15325	COG0640	Transcriptional regulator
KM392_15340	COG0443	Heat shock 70 kDa protein
KM392_15355	COG1522	sequence-specific DNA binding
KM392_15370	COG0346	lactoylglutathione lyase activity
KM392_15390	COG2169	Transcriptional regulator
KM392_15435	COG2814	Major facilitator Superfamily
KM392_15460	COG0745	RESPONSE REGULATOR receiver
KM392_15465	COG3850	Histidine kinase
KM392_15465	COG5002	protein histidine kinase activity
KM392_15490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM392_15510	COG1476	TRANSCRIPTIONal
KM392_15525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_15530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM392_15540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_15545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM392_15560	COG1136	(ABC) transporter
KM392_15565	COG0577	efflux transmembrane transporter activity
KM392_15580	COG3850	Histidine kinase
KM392_15580	COG5002	protein histidine kinase activity
KM392_15590	COG2364	Membrane
KM392_15595	COG1846	Transcriptional regulator
KM392_15605	COG2808	Putative FMN-binding domain
KM392_15610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_15615	COG2271	Major facilitator Superfamily
KM392_15620	COG1556	Lactate utilization protein
KM392_15625	COG1139	Iron-sulfur cluster binding protein
KM392_15635	COG0583	DNA-binding transcription factor activity
KM392_15645	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM392_15675	COG0673	inositol 2-dehydrogenase activity
KM392_15680	COG0561	phosphatase activity
KM392_15690	COG1609	Transcriptional regulator
KM392_15695	COG0457	Tetratricopeptide repeat
KM392_15715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM392_15745	COG0534	Mate efflux family protein
KM392_15765	COG2814	Major facilitator Superfamily
KM392_15770	COG1309	transcriptional regulator
KM392_15785	COG0814	amino acid
KM392_15790	COG1760	l-serine dehydratase
KM392_15795	COG1760	l-serine dehydratase
KM392_15805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM392_15810	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM392_15825	COG1522	sequence-specific DNA binding
KM392_15830	COG0531	amino acid
KM392_15845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM392_15865	COG1595	DNA-templated transcription, initiation
KM392_15880	COG0662	Cupin 2, conserved barrel domain protein
KM392_15885	COG2207	Transcriptional regulator
KM392_15885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_15935	COG0477	Major facilitator Superfamily
KM392_15945	COG1846	Transcriptional regulator
KM392_15950	COG2814	Major facilitator Superfamily
KM392_15960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM392_15965	COG1131	(ABC) transporter
KM392_15985	COG2076	Multidrug Resistance protein
KM392_15990	COG1309	transcriptional regulator
KM392_16000	COG2031	fatty acid transporter
KM392_16010	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM392_16040	COG1122	ATPase activity
KM392_16045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM392_16060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM392_16065	COG1288	antiporter activity
KM392_16070	COG2356	endonuclease I
KM392_16085	COG3620	sequence-specific DNA binding
KM392_16090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM392_16095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM392_16100	COG0124	histidyl-tRNA synthetase
KM392_16115	COG1733	regulation of RNA biosynthetic process
KM392_16120	COG0778	Nitroreductase
KM392_16140	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_16150	COG1131	(ABC) transporter
KM392_16175	COG1011	Hydrolase
KM392_16185	COG2365	Tyrosine phosphatase family
KM392_16210	COG0346	lactoylglutathione lyase activity
KM392_16215	COG1940	carbohydrate kinase activity
KM392_16220	COG0738	Major facilitator superfamily
KM392_16225	COG0110	maltose O-acetyltransferase activity
KM392_16235	COG0577	efflux transmembrane transporter activity
KM392_16235	COG1136	(ABC) transporter
KM392_16250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM392_16255	COG0628	permease
KM392_16275	COG2226	methyltransferase
KM392_16285	COG0477	Major facilitator Superfamily
KM392_16315	COG1253	flavin adenine dinucleotide binding
KM392_16320	COG0789	Transcriptional regulator
KM392_16325	COG0697	spore germination
KM392_16330	COG1357	PFAM Pentapeptide repeats (8 copies)
KM392_16335	COG3813	Protein conserved in bacteria
KM392_16340	COG2706	6-phosphogluconolactonase activity
KM392_16345	COG1070	Carbohydrate kinase
KM392_16355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM392_16360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM392_16375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM392_16380	COG0604	alcohol dehydrogenase
KM392_16385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM392_16395	COG3321	synthase
KM392_16395	COG0604	alcohol dehydrogenase
KM392_16400	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_16425	COG0656	L-ascorbic acid biosynthetic process
KM392_16430	COG2814	Major facilitator Superfamily
KM392_16445	COG0346	lactoylglutathione lyase activity
KM392_16450	COG0814	amino acid
KM392_16475	COG1393	Belongs to the ArsC family
KM392_16480	COG1733	regulation of RNA biosynthetic process
KM392_16485	COG2188	Transcriptional regulator
KM392_16490	COG0673	inositol 2-dehydrogenase activity
KM392_16495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM392_16500	COG1733	regulation of RNA biosynthetic process
KM392_16505	COG1733	regulation of RNA biosynthetic process
KM392_16520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_16540	COG0384	phenazine biosynthesis protein PhzF
KM392_16550	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_16560	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_16570	COG1733	regulation of RNA biosynthetic process
KM392_16605	COG1191	sigma factor activity
KM392_16620	COG1309	transcriptional regulator
KM392_16640	COG3152	Membrane
KM392_16665	COG1151	hydroxylamine reductase activity
KM392_16675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_16680	COG3409	Peptidoglycan-binding domain 1 protein
KM392_16680	COG3757	hydrolase, family 25
KM392_16715	COG2072	flavoprotein involved in K transport
KM392_16750	COG0604	alcohol dehydrogenase
KM392_16755	COG1113	amino acid transport
KM392_16760	COG2814	Major facilitator Superfamily
KM392_16790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM392_16795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM392_16815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_16820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_16825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_16830	COG3739	integral membrane protein
KM392_16835	COG0384	phenazine biosynthesis protein PhzF
KM392_16865	COG0583	DNA-binding transcription factor activity
KM392_16885	COG1193	negative regulation of DNA recombination
KM392_16900	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM392_16905	COG1164	Oligoendopeptidase f
KM392_16910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM392_16940	COG0584	glycerophosphoryl diester phosphodiesterase
KM392_16965	COG0640	Transcriptional regulator
KM392_16970	COG0604	alcohol dehydrogenase
KM392_16990	COG2808	Putative FMN-binding domain
KM392_17005	COG0385	Bile acid
KM392_17010	COG0277	FAD linked oxidase domain protein
KM392_17040	COG1216	Glycosyl transferase, family 2
KM392_17045	COG1024	Enoyl-CoA hydratase
KM392_17055	COG1285	pathogenesis
KM392_17070	COG2514	catechol 2,3-dioxygenase activity
KM392_17075	COG2720	vancomycin resistance protein
KM392_17115	COG0716	FMN binding
KM392_17145	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_17170	COG4145	pantothenate transmembrane transporter activity
KM392_17180	COG1012	belongs to the aldehyde dehydrogenase family
KM392_17185	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_17195	COG1657	PFAM Prenyltransferase squalene oxidase
KM392_17200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM392_17205	COG2962	Rard protein
KM392_17210	COG3326	Membrane
KM392_17225	COG0489	protein tyrosine kinase activity
KM392_17235	COG0314	molybdopterin synthase activity
KM392_17240	COG0303	'Molybdopterin
KM392_17245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM392_17250	COG2116	formate transmembrane transporter activity
KM392_17260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM392_17265	COG5609	conserved protein (DUF2294)
KM392_17270	COG2427	Protein of unknown function (DUF1641)
KM392_17285	COG0697	spore germination
KM392_17325	COG2226	methyltransferase
KM392_17330	COG4166	transmembrane transport
KM392_17335	COG4166	transmembrane transport
KM392_17340	COG1301	dicarboxylic acid transport
KM392_17345	COG1316	TRANSCRIPTIONal
KM392_17355	COG1595	DNA-templated transcription, initiation
KM392_17375	COG1131	(ABC) transporter
KM392_17385	COG0673	inositol 2-dehydrogenase activity
KM392_17390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM392_17395	COG0187	DNA topoisomerase II activity
KM392_17400	COG1832	CoA-binding protein
KM392_17405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM392_17410	COG0745	RESPONSE REGULATOR receiver
KM392_17425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM392_17430	COG4841	protein insertion into membrane
KM392_17435	COG0824	Thioesterase
KM392_17465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM392_17475	COG2274	protein secretion by the type I secretion system
KM392_17480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM392_17520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM392_17535	COG0183	Belongs to the thiolase family
KM392_17540	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_17545	COG1268	BioY protein
KM392_17550	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_17600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_17610	COG5002	protein histidine kinase activity
KM392_17615	COG0400	carboxylic ester hydrolase activity
KM392_17620	COG0346	lactoylglutathione lyase activity
KM392_17625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM392_17630	COG0069	glutamate synthase activity
KM392_17635	COG1902	pentaerythritol trinitrate reductase activity
KM392_17640	COG1329	Transcriptional regulator
KM392_17645	COG0010	Belongs to the arginase family
KM392_17670	COG2226	methyltransferase
KM392_17725	COG4846	Membrane protein involved in cytochrome C biogenesis
KM392_17730	COG0785	Cytochrome C biogenesis protein
KM392_17740	COG0583	DNA-binding transcription factor activity
KM392_17745	COG1380	Effector of murein hydrolase LrgA
KM392_17750	COG1346	cytolysis
KM392_17775	COG3409	Peptidoglycan-binding domain 1 protein
KM392_17775	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM392_17790	COG1132	(ABC) transporter
KM392_17795	COG1132	(ABC) transporter
KM392_17825	COG3639	organic phosphonate transmembrane transporter activity
KM392_17830	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM392_17850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM392_17870	COG1695	Transcriptional regulator
KM392_17905	COG3409	Peptidoglycan-binding domain 1 protein
KM392_17905	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM392_17905	COG1388	LysM domain
KM392_17910	COG4824	toxin secretion phage lysis holin
KM392_18055	COG1595	DNA-templated transcription, initiation
KM392_18100	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM392_18185	COG1396	sequence-specific DNA binding
KM392_18210	COG0174	glutamine synthetase
KM392_18215	COG0789	Transcriptional regulator
KM392_18220	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM392_18225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM392_18230	COG2860	membrane
KM392_18235	COG0464	growth
KM392_18265	COG1388	LysM domain
KM392_18265	COG3584	3D domain protein
KM392_18270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM392_18270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM392_18270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM392_18275	COG1105	Belongs to the carbohydrate kinase PfkB family
KM392_18280	COG1349	DNA-binding transcription factor activity
KM392_18290	COG2322	membrane
KM392_18300	COG1113	amino acid transport
KM392_18315	COG1408	metallophosphoesterase
KM392_18320	COG2116	formate transmembrane transporter activity
KM392_18330	COG2217	Heavy metal translocating P-type atpase
KM392_18335	COG2608	mercury ion transmembrane transporter activity
KM392_18340	COG1937	Protein conserved in bacteria
KM392_18350	COG2819	hydrolase of the alpha beta superfamily
KM392_18355	COG1120	ATPase activity
KM392_18360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_18380	COG2169	Transcriptional regulator
KM392_18385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM392_18390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM392_18400	COG2364	Membrane
KM392_18415	COG2267	carboxylic ester hydrolase activity
KM392_18420	COG0346	lactoylglutathione lyase activity
KM392_18445	COG1346	cytolysis
KM392_18450	COG1380	Effector of murein hydrolase LrgA
KM392_18455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM392_18460	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM392_18460	COG0596	Alpha beta hydrolase
KM392_18465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM392_18485	COG1404	Belongs to the peptidase S8 family
KM392_18490	COG3773	Cell wall hydrolase
KM392_18495	COG0562	UDP-galactopyranose mutase
KM392_18500	COG1368	sulfuric ester hydrolase activity
KM392_18505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM392_18515	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM392_18540	COG1131	(ABC) transporter
KM392_18560	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM392_18565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM392_18570	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM392_18575	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM392_18575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM392_18585	COG2359	stage V sporulation protein S
KM392_18590	COG1692	metallophosphoesterase
KM392_18615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM392_18620	COG1426	Protein conserved in bacteria
KM392_18635	COG0300	oxidoreductase activity
KM392_18640	COG0612	Peptidase, M16
KM392_18645	COG0612	Peptidase, M16
KM392_18660	COG3845	ABC transporter
KM392_18665	COG1744	ABC transporter substrate-binding protein PnrA-like
KM392_18670	COG2188	Transcriptional regulator
KM392_18675	COG1674	ftsk spoiiie
KM392_18685	COG0740	serine-type endopeptidase activity
KM392_18690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM392_18700	COG0527	aspartate kinase activity
KM392_18705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM392_18710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM392_18715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM392_18720	COG1873	PFAM PRC-barrel domain
KM392_18725	COG0612	Peptidase, M16
KM392_18730	COG0726	polysaccharide deacetylase
KM392_18745	COG0196	riboflavin kinase activity
KM392_18750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM392_18760	COG1550	Protein conserved in bacteria
KM392_18770	COG1358	cellular component organization or biogenesis
KM392_18775	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM392_18780	COG0195	Participates in both transcription termination and antitermination
KM392_18800	COG0750	zinc metalloprotease
KM392_18810	COG4589	Belongs to the CDS family
KM392_18825	COG0528	UMP kinase activity
KM392_18855	COG4974	Belongs to the 'phage' integrase family
KM392_18865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM392_18875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM392_18915	COG1837	Belongs to the UPF0109 family
KM392_18925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM392_18935	COG0552	protein localization to endoplasmic reticulum
KM392_18940	COG1196	nuclear chromosome segregation
KM392_18950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM392_18955	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_18960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM392_18975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM392_18980	COG1461	Dihydroxyacetone kinase
KM392_18985	COG1302	Protein conserved in bacteria
KM392_19000	COG1564	THIamine pyrophosphokinase
KM392_19005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM392_19010	COG1162	GTPase activity
KM392_19015	COG0515	serine threonine protein kinase
KM392_19015	COG2815	serine threonine protein kinase
KM392_19020	COG0631	protein serine/threonine phosphatase activity
KM392_19030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM392_19030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM392_19040	COG0242	peptide deformylase activity
KM392_19045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM392_19050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM392_19070	COG1561	YicC-like family, N-terminal region
KM392_19075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM392_19085	COG0006	proline dipeptidase activity
KM392_19105	COG3069	C4-dicarboxylate transmembrane transporter activity
KM392_19170	COG0564	pseudouridine synthase activity
KM392_19190	COG3599	regulation of cell shape
KM392_19195	COG2302	S4 RNA-binding domain
KM392_19200	COG0762	integral membrane protein
KM392_19210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM392_19215	COG1496	oxidoreductase activity
KM392_19220	COG1873	PFAM PRC-barrel domain
KM392_19225	COG1191	sigma factor activity
KM392_19230	COG1191	sigma factor activity
KM392_19240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM392_19245	COG0849	cell division
KM392_19250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM392_19255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM392_19265	COG0772	Belongs to the SEDS family
KM392_19280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM392_19285	COG0768	penicillin binding
KM392_19290	COG0768	penicillin binding
KM392_19295	COG4839	cell division protein FtsL
KM392_19310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM392_19325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM392_19330	COG1399	metal-binding, possibly nucleic acid-binding protein
KM392_19380	COG4824	toxin secretion phage lysis holin
KM392_19465	COG4626	Terminase
KM392_19465	COG1802	Transcriptional regulator
KM392_19490	COG0582	viral genome integration into host DNA
KM392_19555	COG0756	dUTP diphosphatase activity
KM392_19595	COG1484	DNA-dependent DNA replication
KM392_19620	COG1396	sequence-specific DNA binding
KM392_19635	COG1396	sequence-specific DNA binding
KM392_19650	COG0582	viral genome integration into host DNA
KM392_19660	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM392_19665	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM392_19670	COG3314	Sporulation integral membrane protein YlbJ
KM392_19680	COG0742	ribosomal rna small subunit methyltransferase
KM392_19695	COG3679	Belongs to the UPF0342 family
KM392_19700	COG0406	alpha-ribazole phosphatase activity
KM392_19715	COG2340	Cysteine-rich secretory protein family
KM392_19730	COG3336	cytochrome c oxidase
KM392_19765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM392_19770	COG0772	Belongs to the SEDS family
KM392_19780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM392_19785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM392_19795	COG4896	Protein conserved in bacteria
KM392_19810	COG1217	gtp-binding protein TYPA
KM392_19820	COG0483	inositol monophosphate 1-phosphatase activity
KM392_19840	COG1982	Orn Lys Arg decarboxylase major
KM392_19890	COG0022	dehydrogenase e1 component
KM392_19895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM392_19905	COG0242	peptide deformylase activity
KM392_19920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM392_19925	COG0569	domain protein
KM392_19945	COG0583	DNA-binding transcription factor activity
KM392_19950	COG0517	IMP dehydrogenase activity
KM392_19960	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM392_19970	COG4703	Protein of unknown function (DUF1797)
KM392_19985	COG2200	EAL domain
KM392_19990	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_19995	COG1408	metallophosphoesterase
KM392_20040	COG2814	Major facilitator Superfamily
KM392_20060	COG3209	COG3209 Rhs family protein
KM392_20070	COG2205	protein histidine kinase activity
KM392_20080	COG0436	Aminotransferase
KM392_20085	COG1609	Transcriptional regulator
KM392_20090	COG3833	ABC-type maltose transport systems, permease component
KM392_20095	COG1175	transmembrane transport
KM392_20100	COG2182	Extracellular solute-binding protein
KM392_20110	COG0366	Alpha amylase catalytic
KM392_20115	COG3842	ATPase activity
KM392_20155	COG0183	Belongs to the thiolase family
KM392_20190	COG1695	Transcriptional regulator
KM392_20195	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_20205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM392_20215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM392_20220	COG0436	Aminotransferase
KM392_20240	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM392_20260	COG2199	diguanylate cyclase activity
KM392_20265	COG0778	Nitroreductase
KM392_20290	COG2190	(PTS) system
KM392_20290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM392_20290	COG1263	PTS System
KM392_20295	COG3711	transcriptional antiterminator
KM392_20305	COG2188	Transcriptional regulator
KM392_20315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM392_20345	COG0456	acetyltransferase
KM392_20350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM392_20355	COG4086	secreted protein
KM392_20360	COG0561	phosphatase activity
KM392_20365	COG0697	spore germination
KM392_20380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_20405	COG0733	neurotransmitter:sodium symporter activity
KM392_20425	COG1686	Belongs to the peptidase S11 family
KM392_20430	COG1725	Transcriptional regulator
KM392_20435	COG1131	(ABC) transporter
KM392_20450	COG1846	Transcriptional regulator
KM392_20465	COG0598	Magnesium transport protein CorA
KM392_20490	COG4974	Belongs to the 'phage' integrase family
KM392_20500	COG0735	belongs to the Fur family
KM392_20505	COG1300	Membrane
KM392_20525	COG0667	Aldo Keto reductase
KM392_20530	COG0656	L-ascorbic acid biosynthetic process
KM392_20535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM392_20535	COG0456	acetyltransferase
KM392_20545	COG1525	nuclease
KM392_20545	COG4085	toxin activity
KM392_20545	COG0737	Belongs to the 5'-nucleotidase family
KM392_20555	COG0596	Alpha beta hydrolase
KM392_20560	COG2056	Na+-H+ antiporter family
KM392_20565	COG1609	Transcriptional regulator
KM392_20570	COG0456	acetyltransferase
KM392_20575	COG1073	alpha beta
KM392_20590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM392_20590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM392_20595	COG0307	riboflavin synthase, alpha
KM392_20620	COG4106	trans-aconitate 2-methyltransferase activity
KM392_20625	COG2226	methyltransferase
KM392_20625	COG1073	alpha beta
KM392_20640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM392_20650	COG1757	Na H antiporter
KM392_20655	COG0737	Belongs to the 5'-nucleotidase family
KM392_20665	COG1522	sequence-specific DNA binding
KM392_20685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM392_20695	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM392_20710	COG0300	oxidoreductase activity
KM392_20715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_20720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM392_20725	COG1760	l-serine dehydratase
KM392_20730	COG1760	l-serine dehydratase
KM392_20750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM392_20760	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM392_20765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_20780	COG1376	ErfK ybiS ycfS ynhG family protein
KM392_20785	COG4129	membrane
KM392_20790	COG1126	abc transporter atp-binding protein
KM392_20795	COG0765	amino acid transport
KM392_20800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM392_20815	COG2816	NAD+ diphosphatase activity
KM392_20820	COG0772	Belongs to the SEDS family
KM392_20825	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM392_20830	COG0022	dehydrogenase e1 component
KM392_20835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM392_20840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM392_20855	COG0280	phosphate acetyltransferase
KM392_20860	COG3290	protein histidine kinase activity
KM392_20860	COG3829	transcription factor binding
KM392_20870	COG0584	glycerophosphoryl diester phosphodiesterase
KM392_20875	COG3093	addiction module antidote protein HigA
KM392_20885	COG0745	RESPONSE REGULATOR receiver
KM392_20890	COG0750	zinc metalloprotease
KM392_20895	COG0497	DNA recombination
KM392_20905	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM392_20915	COG0142	geranyltranstransferase activity
KM392_20940	COG1302	Protein conserved in bacteria
KM392_20945	COG0439	Biotin carboxylase
KM392_20950	COG0511	ligase activity, forming carbon-carbon bonds
KM392_20995	COG3854	ATPases associated with a variety of cellular activities
KM392_21020	COG0006	proline dipeptidase activity
KM392_21035	COG3872	metal-dependent enzyme
KM392_21045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM392_21065	COG0095	Lipoate-protein ligase
KM392_21070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_21075	COG1609	Transcriptional regulator
KM392_21085	COG2076	Multidrug Resistance protein
KM392_21090	COG2076	Multidrug Resistance protein
KM392_21125	COG1131	(ABC) transporter
KM392_21130	COG1725	Transcriptional regulator
KM392_21160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM392_21215	COG4970	Tfp pilus assembly protein FimT
KM392_21220	COG4537	Required for transformation and DNA binding
KM392_21225	COG1459	type II secretion system
KM392_21230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM392_21280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM392_21290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM392_21290	COG0646	methionine synthase
KM392_21295	COG0626	cystathionine gamma-synthase activity
KM392_21300	COG0626	cystathionine gamma-synthase activity
KM392_21320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_21330	COG1940	carbohydrate kinase activity
KM392_21335	COG4483	Protein conserved in bacteria
KM392_21340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM392_21345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM392_21350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM392_21355	COG0704	Plays a role in the regulation of phosphate uptake
KM392_21365	COG0581	inorganic phosphate transmembrane transporter activity
KM392_21370	COG0573	inorganic phosphate transmembrane transporter activity
KM392_21375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM392_21380	COG0768	penicillin binding
KM392_21385	COG0477	Major facilitator Superfamily
KM392_21390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM392_21415	COG0735	belongs to the Fur family
KM392_21420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM392_21425	COG1121	(ABC) transporter
KM392_21430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_21460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM392_21465	COG2384	SAM-dependent methyltransferase
KM392_21470	COG2010	Cytochrome c
KM392_21475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM392_21480	COG0358	DNA primase activity
KM392_21490	COG0517	IMP dehydrogenase activity
KM392_21505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM392_21510	COG0295	cytidine deaminase activity
KM392_21515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM392_21525	COG1480	7TM receptor with intracellular HD hydrolase
KM392_21530	COG1702	phosphate starvation-inducible protein PhoH
KM392_21545	COG1610	YqeY-like protein
KM392_21550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM392_21555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM392_21560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM392_21590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM392_21595	COG1733	regulation of RNA biosynthetic process
KM392_21620	COG1466	dna polymerase III delta subunit
KM392_21635	COG2131	deaminase
KM392_21640	COG1596	polysaccharide export
KM392_21640	COG1555	photosystem II stabilization
KM392_21645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM392_21650	COG2226	methyltransferase
KM392_21655	COG0799	negative regulation of ribosome biogenesis
KM392_21660	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM392_21670	COG1534	Rna-binding protein
KM392_21680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM392_21685	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM392_21710	COG1595	DNA-templated transcription, initiation
KM392_21720	COG0778	Nitroreductase
KM392_21725	COG2357	RelA SpoT domain protein
KM392_21735	COG1785	Belongs to the alkaline phosphatase family
KM392_21745	COG2267	carboxylic ester hydrolase activity
KM392_21780	COG1404	Belongs to the peptidase S8 family
KM392_21785	COG3186	Phenylalanine-4-hydroxylase
KM392_21795	COG2514	catechol 2,3-dioxygenase activity
KM392_21800	COG2259	Doxx family
KM392_21840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_21850	COG1012	belongs to the aldehyde dehydrogenase family
KM392_21850	COG1454	alcohol dehydrogenase
KM392_21855	COG0626	cystathionine gamma-synthase activity
KM392_21860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM392_21885	COG0768	penicillin binding
KM392_21900	COG0826	peptidase U32
KM392_21905	COG0826	peptidase U32
KM392_21910	COG4122	O-methyltransferase activity
KM392_21915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM392_21935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM392_21945	COG0628	permease
KM392_21965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM392_21975	COG0482	sulfurtransferase activity
KM392_21980	COG1104	cysteine desulfurase activity
KM392_21985	COG1959	2 iron, 2 sulfur cluster binding
KM392_21990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM392_22000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM392_22025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM392_22035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM392_22035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM392_22040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM392_22045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM392_22045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM392_22055	COG2244	polysaccharide biosynthetic process
KM392_22060	COG2323	membrane
KM392_22070	COG1862	Preprotein translocase
KM392_22100	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM392_22110	COG0697	spore germination
KM392_22115	COG0697	spore germination
KM392_22120	COG0640	Transcriptional regulator
KM392_22145	COG0157	Belongs to the NadC ModD family
KM392_22150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM392_22155	COG1104	cysteine desulfurase activity
KM392_22160	COG1827	regulation of RNA biosynthetic process
KM392_22165	COG2258	MOSC domain
KM392_22170	COG0077	Prephenate dehydratase
KM392_22175	COG0577	efflux transmembrane transporter activity
KM392_22180	COG0577	efflux transmembrane transporter activity
KM392_22185	COG1136	(ABC) transporter
KM392_22195	COG0745	RESPONSE REGULATOR receiver
KM392_22200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM392_22205	COG3290	protein histidine kinase activity
KM392_22215	COG2868	ribosomal protein
KM392_22225	COG1530	ribonuclease E activity
KM392_22230	COG1994	Peptidase M50
KM392_22235	COG0739	heme binding
KM392_22240	COG2894	cell division
KM392_22260	COG1077	Cell shape determining protein MreB Mrl
KM392_22280	COG0285	dihydrofolate synthase activity
KM392_22285	COG0525	valine-tRNA ligase activity
KM392_22295	COG1388	LysM domain
KM392_22305	COG0113	porphobilinogen synthase activity
KM392_22310	COG1587	Uroporphyrinogen-III synthase
KM392_22320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM392_22330	COG1846	Transcriptional regulator
KM392_22335	COG1764	response to oxidative stress
KM392_22350	COG1067	ATP-dependent peptidase activity
KM392_22350	COG0470	DNA polymerase III
KM392_22395	COG0622	Phosphoesterase
KM392_22410	COG5401	PFAM Sporulation and spore germination
KM392_22430	COG1309	transcriptional regulator
KM392_22445	COG2197	response regulator
KM392_22450	COG2233	PERMEase
KM392_22460	COG0402	S-adenosylhomocysteine deaminase activity
KM392_22465	COG0402	S-adenosylhomocysteine deaminase activity
KM392_22475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM392_22485	COG0444	Belongs to the ABC transporter superfamily
KM392_22490	COG4608	Belongs to the ABC transporter superfamily
KM392_22495	COG3275	phosphorelay sensor kinase activity
KM392_22500	COG3279	Response regulator of the LytR AlgR family
KM392_22515	COG1983	PspC domain protein
KM392_22520	COG1396	sequence-specific DNA binding
KM392_22525	COG0697	spore germination
KM392_22535	COG1959	2 iron, 2 sulfur cluster binding
KM392_22540	COG1668	transmembrane transport
KM392_22550	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM392_22560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM392_22565	COG1876	peptidase activity
KM392_22570	COG0824	Thioesterase
KM392_22575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM392_22580	COG1053	succinate dehydrogenase
KM392_22585	COG2009	succinate dehydrogenase
KM392_22590	COG1719	4-vinyl reductase, 4VR
KM392_22600	COG3118	belongs to the thioredoxin family
KM392_22605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM392_22610	COG2086	electron transfer activity
KM392_22615	COG1024	Enoyl-CoA hydratase
KM392_22620	COG1309	transcriptional regulator
KM392_22625	COG0318	PFAM AMP-dependent synthetase and ligase
KM392_22645	COG2318	DinB family
KM392_22675	COG1131	(ABC) transporter
KM392_22680	COG2205	protein histidine kinase activity
KM392_22685	COG0745	RESPONSE REGULATOR receiver
KM392_22695	COG4895	conserved protein (DUF2196)
KM392_22700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM392_22715	COG4509	Sortase family
KM392_22720	COG1120	ATPase activity
KM392_22735	COG5386	Cell surface protein
KM392_22745	COG5386	Cell surface protein
KM392_22750	COG1114	Component of the transport system for branched-chain amino acids
KM392_22755	COG1187	pseudouridine synthase activity
KM392_22765	COG1796	DNA polymerase
KM392_22765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM392_22770	COG1286	toxin biosynthetic process
KM392_22815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM392_22825	COG1418	mRNA catabolic process
KM392_22850	COG2814	Major facilitator Superfamily
KM392_22855	COG1566	PFAM secretion protein HlyD family protein
KM392_22860	COG1309	transcriptional regulator
KM392_22865	COG1363	Peptidase, m42
KM392_22890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM392_22900	COG1484	DNA-dependent DNA replication
KM392_22905	COG3611	Membrane attachment protein
KM392_22915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM392_22920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM392_22925	COG0237	dephospho-CoA kinase activity
KM392_22930	COG1971	Probably functions as a manganese efflux pump
KM392_22940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM392_22940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM392_22945	COG5002	protein histidine kinase activity
KM392_22950	COG0745	RESPONSE REGULATOR receiver
KM392_22970	COG0538	isocitrate dehydrogenase activity
KM392_22975	COG0372	Belongs to the citrate synthase family
KM392_22985	COG0628	permease
KM392_22990	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM392_23015	COG1725	Transcriptional regulator
KM392_23020	COG0281	malic enzyme
KM392_23025	COG0587	DNA-directed DNA polymerase activity
KM392_23040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM392_23060	COG4109	DRTGG domain
KM392_23075	COG0006	proline dipeptidase activity
KM392_23110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_23115	COG0662	Cupin 2, conserved barrel domain protein
KM392_23125	COG1476	TRANSCRIPTIONal
KM392_23140	COG1028	Short-chain dehydrogenase reductase Sdr
KM392_23145	COG0589	response to stress
KM392_23185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_23205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM392_23210	COG0827	DNA restriction-modification system
KM392_23215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM392_23220	COG3874	Sporulation protein YtfJ
KM392_23235	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM392_23245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM392_23260	COG1104	cysteine desulfurase activity
KM392_23270	COG0583	DNA-binding transcription factor activity
KM392_23275	COG0697	spore germination
KM392_23285	COG1956	GAF domain-containing protein
KM392_23290	COG0626	cystathionine gamma-synthase activity
KM392_23320	COG1595	DNA-templated transcription, initiation
KM392_23330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM392_23335	COG0454	-acetyltransferase
KM392_23340	COG0517	IMP dehydrogenase activity
KM392_23345	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM392_23355	COG0745	RESPONSE REGULATOR receiver
KM392_23365	COG0666	response to abiotic stimulus
KM392_23400	COG1609	Transcriptional regulator
KM392_23405	COG4851	CamS sex pheromone cAM373 precursor
KM392_23410	COG3118	belongs to the thioredoxin family
KM392_23420	COG2309	aminopeptidase activity
KM392_23440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_23455	COG1674	ftsk spoiiie
KM392_23465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM392_23470	COG4848	Belongs to the UPF0354 family
KM392_23475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM392_23480	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM392_23485	COG1363	Peptidase, m42
KM392_23495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_23510	COG0510	thiamine kinase activity
KM392_23515	COG1523	belongs to the glycosyl hydrolase 13 family
KM392_23525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM392_23530	COG1349	DNA-binding transcription factor activity
KM392_23535	COG1187	pseudouridine synthase activity
KM392_23540	COG2244	polysaccharide biosynthetic process
KM392_23545	COG2081	HI0933 family
KM392_23550	COG2814	Major facilitator Superfamily
KM392_23560	COG3832	glyoxalase III activity
KM392_23580	COG1329	Transcriptional regulator
KM392_23590	COG4975	Glucose uptake
KM392_23605	COG0314	molybdopterin synthase activity
KM392_23610	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM392_23615	COG0303	'Molybdopterin
KM392_23625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM392_23630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM392_23650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM392_23660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM392_23705	COG2814	Major facilitator Superfamily
KM392_23710	COG0475	glutathione-regulated potassium exporter activity
KM392_23715	COG0490	domain, Protein
KM392_23720	COG0582	viral genome integration into host DNA
KM392_23730	COG1136	(ABC) transporter
KM392_23750	COG1242	4 iron, 4 sulfur cluster binding
KM392_23755	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM392_23760	COG1131	(ABC) transporter
KM392_23770	COG1794	racemase activity, acting on amino acids and derivatives
KM392_23790	COG2267	carboxylic ester hydrolase activity
KM392_23795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM392_23800	COG0671	phosphoesterase, PA-phosphatase related
KM392_23805	COG0438	transferase activity, transferring glycosyl groups
KM392_23815	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM392_23870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM392_23875	COG5002	protein histidine kinase activity
KM392_23880	COG4191	Histidine kinase
KM392_23885	COG2267	carboxylic ester hydrolase activity
KM392_23905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM392_23910	COG1116	anion transmembrane transporter activity
KM392_23915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM392_23940	COG0494	nUDIX hydrolase
KM392_23970	COG0288	reversible hydration of carbon dioxide
KM392_23975	COG1271	oxidase subunit
KM392_23980	COG1294	oxidase, subunit
KM392_24000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_24025	COG1842	Phage shock protein A
KM392_24055	COG5002	protein histidine kinase activity
KM392_24060	COG0745	RESPONSE REGULATOR receiver
KM392_24085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM392_24090	COG1597	lipid kinase activity
KM392_24125	COG0586	Pfam SNARE associated Golgi protein
KM392_24135	COG0577	efflux transmembrane transporter activity
KM392_24140	COG1136	(ABC) transporter
KM392_24150	COG0745	RESPONSE REGULATOR receiver
KM392_24155	COG2205	protein histidine kinase activity
KM392_24160	COG0577	efflux transmembrane transporter activity
KM392_24165	COG0577	efflux transmembrane transporter activity
KM392_24170	COG1136	(ABC) transporter
KM392_24190	COG2188	Transcriptional regulator
KM392_24210	COG3964	amidohydrolase
KM392_24240	COG4948	Mandelate Racemase Muconate Lactonizing
KM392_24250	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM392_24255	COG0596	Alpha beta hydrolase
KM392_24260	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM392_24265	COG1169	isochorismate synthase
KM392_24270	COG1575	Belongs to the MenA family. Type 1 subfamily
KM392_24275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM392_24295	COG0058	SHG alpha-glucan phosphorylase activity
KM392_24300	COG0297	glycogen (starch) synthase activity
KM392_24305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM392_24425	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM392_24460	COG1285	pathogenesis
KM392_24465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM392_24475	COG0166	Belongs to the GPI family
KM392_24480	COG2155	Conserved Protein
KM392_24485	COG1098	S1 RNA binding domain
KM392_24490	COG0436	Aminotransferase
KM392_24495	COG1522	sequence-specific DNA binding
KM392_24500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM392_24505	COG2267	carboxylic ester hydrolase activity
KM392_24515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM392_24535	COG5018	Exonuclease
KM392_24540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM392_24560	COG2050	protein possibly involved in aromatic compounds catabolism
KM392_24570	COG1268	BioY protein
KM392_24580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM392_24585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM392_24600	COG3584	3D domain protein
KM392_24615	COG1252	NADH dehydrogenase
KM392_24630	COG3708	Transcriptional regulator
KM392_24645	COG1683	Conserved Protein
KM392_24665	COG0316	Belongs to the HesB IscA family
KM392_24680	COG1252	NADH dehydrogenase
KM392_24690	COG2274	protein secretion by the type I secretion system
KM392_24695	COG0390	transport system, permease component
KM392_24700	COG2824	Alkylphosphonate utilization operon protein PhnA
KM392_24740	COG4837	Protein of unknown function (DUF1462)
KM392_24745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM392_24755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM392_24760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM392_24770	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM392_24775	COG0647	UMP catabolic process
KM392_24785	COG2445	Protein of unknown function DUF86
KM392_24790	COG1494	fructose-1,6-bisphosphatase
KM392_24805	COG4470	Protein conserved in bacteria
KM392_24815	COG0789	Transcriptional regulator
KM392_24820	COG4377	Putative membrane peptidase family (DUF2324)
KM392_24845	COG0739	heme binding
KM392_24855	COG3377	Domain of unknown function (DUF1805)
KM392_24860	COG0737	Belongs to the 5'-nucleotidase family
KM392_24865	COG1695	Transcriptional regulator
KM392_24875	COG0719	Fe-S assembly protein
KM392_24880	COG0822	iron-sulfur transferase activity
KM392_24885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM392_24890	COG0719	Fe-S assembly protein
KM392_24895	COG0396	ATPase activity
KM392_24900	COG1464	Belongs to the NlpA lipoprotein family
KM392_24905	COG1464	Belongs to the NlpA lipoprotein family
KM392_24910	COG2011	ABC-type metal ion transport system permease component
KM392_24915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM392_24925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM392_24930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM392_24940	COG1393	Belongs to the ArsC family
KM392_24985	COG0039	L-malate dehydrogenase activity
KM392_25005	COG1309	transcriptional regulator
KM392_25010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM392_25015	COG1960	acyl-CoA dehydrogenase activity
KM392_25020	COG0183	Belongs to the thiolase family
KM392_25025	COG1024	Enoyl-CoA hydratase
KM392_25025	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM392_25035	COG1686	Belongs to the peptidase S11 family
KM392_25050	COG0011	TIGRFAM Protein of
KM392_25055	COG0840	transmembrane signaling receptor activity
KM392_25075	COG2814	Major facilitator Superfamily
KM392_25080	COG0531	amino acid
KM392_25090	COG0706	membrane insertase activity
KM392_25100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM392_25135	COG0586	Pfam SNARE associated Golgi protein
KM392_25145	COG1376	ErfK ybiS ycfS ynhG family protein
KM392_25150	COG0745	RESPONSE REGULATOR receiver
KM392_25155	COG5002	protein histidine kinase activity
KM392_25180	COG2151	metal-sulfur cluster biosynthetic enzyme
KM392_25185	COG3227	Zinc metalloprotease (Elastase)
KM392_25190	COG1741	Belongs to the pirin family
KM392_25205	COG0475	glutathione-regulated potassium exporter activity
KM392_25210	COG0490	domain, Protein
KM392_25215	COG1115	amino acid carrier protein
KM392_25220	COG0783	Belongs to the Dps family
KM392_25235	COG1611	Belongs to the LOG family
KM392_25255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_25260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_25265	COG1115	amino acid carrier protein
KM392_25270	COG1115	amino acid carrier protein
KM392_25275	COG2910	NAD(P)H-binding
KM392_25290	COG0656	L-ascorbic acid biosynthetic process
KM392_25295	COG2814	Major facilitator Superfamily
KM392_25300	COG1733	regulation of RNA biosynthetic process
KM392_25310	COG1252	NADH dehydrogenase
KM392_25315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM392_25320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM392_25330	COG0840	transmembrane signaling receptor activity
KM392_25330	COG3290	protein histidine kinase activity
KM392_25340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM392_25345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM392_25360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM392_25415	COG0557	exoribonuclease II activity
KM392_25420	COG1647	Serine aminopeptidase, S33
KM392_25425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM392_25430	COG1346	cytolysis
KM392_25525	COG4695	Portal protein
KM392_25545	COG4974	Belongs to the 'phage' integrase family
KM392_25560	COG0149	triose-phosphate isomerase activity
KM392_25570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM392_25585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM392_25610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM392_25625	COG2323	membrane
KM392_25630	COG0740	serine-type endopeptidase activity
KM392_25635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM392_25645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM392_25655	COG1051	belongs to the nudix hydrolase family
KM392_25665	COG0492	ferredoxin-NADP+ reductase activity
KM392_25670	COG0457	Tetratricopeptide repeat
KM392_25675	COG0110	maltose O-acetyltransferase activity
KM392_25695	COG1950	PFAM Membrane protein of
KM392_25705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM392_25710	COG0556	nucleotide-excision repair
KM392_25730	COG0789	Transcriptional regulator
KM392_25755	COG2855	membrane
KM392_25760	COG0583	DNA-binding transcription factor activity
KM392_25770	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM392_25775	COG0488	(ABC) transporter
KM392_25785	COG1132	(ABC) transporter
KM392_25790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM392_25795	COG3409	Peptidoglycan-binding domain 1 protein
KM392_25795	COG0793	Belongs to the peptidase S41A family
KM392_25800	COG2177	Part of the ABC transporter FtsEX involved in
KM392_25805	COG2884	Cell division ATP-binding protein ftsE
KM392_25820	COG0653	protein targeting
KM392_25825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM392_25830	COG1278	Cold shock
KM392_25835	COG1040	competence protein
KM392_25845	COG1388	LysM domain
KM392_25845	COG0791	NLP P60 protein
KM392_25850	COG1733	regulation of RNA biosynthetic process
KM392_25855	COG1307	EDD domain protein, DegV family
KM392_25860	COG1739	Uncharacterized protein family UPF0029
KM392_25865	COG1316	TRANSCRIPTIONal
KM392_25870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM392_25875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM392_25880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM392_25890	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM392_25890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM392_25905	COG3394	polysaccharide catabolic process
KM392_25910	COG1486	melibiose metabolic process
KM392_25915	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM392_25920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM392_25930	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM392_25935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM392_25940	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM392_25950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM392_25955	COG1301	dicarboxylic acid transport
KM392_25965	COG0346	lactoylglutathione lyase activity
KM392_25970	COG1511	domain protein
KM392_25975	COG0583	DNA-binding transcription factor activity
KM392_25980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM392_25995	COG1271	oxidase subunit
KM392_26000	COG1294	oxidase, subunit
KM392_26005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM392_26025	COG2389	metal-binding protein
KM392_26035	COG1368	sulfuric ester hydrolase activity
KM392_26050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM392_26060	COG1215	transferase activity, transferring glycosyl groups
KM392_26065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM392_26070	COG1388	LysM domain
KM392_26070	COG3584	3D domain protein
KM392_26095	COG4715	Zinc finger, swim domain protein
KM392_26100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM392_26140	COG0577	efflux transmembrane transporter activity
KM392_26145	COG1136	(ABC) transporter
KM392_26180	COG5002	protein histidine kinase activity
KM392_26185	COG0745	RESPONSE REGULATOR receiver
KM392_26190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM392_26205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM392_26210	COG1134	teichoic acid transport
KM392_26215	COG1682	transport, permease protein
KM392_26220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM392_26265	COG1609	Transcriptional regulator
KM392_26280	COG0739	heme binding
KM392_26300	COG2385	sporulation resulting in formation of a cellular spore
KM392_26315	COG4836	Membrane
KM392_26320	COG1007	ATP synthesis coupled electron transport
KM392_26325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM392_26330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM392_26340	COG0839	Belongs to the complex I subunit 6 family
KM392_26355	COG0649	NAD binding
KM392_26360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM392_26375	COG3300	MHYT domain
KM392_26375	COG5001	Diguanylate cyclase
KM392_26425	COG0356	it plays a direct role in the translocation of protons across the membrane
KM392_26460	COG0698	ribose 5-phosphate isomerase
KM392_26470	COG2190	(PTS) system
KM392_26475	COG2259	Doxx family
KM392_26480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM392_26495	COG0009	L-threonylcarbamoyladenylate synthase
KM392_26510	COG2890	protein-(glutamine-N5) methyltransferase activity
KM392_26530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM392_26535	COG1494	fructose-1,6-bisphosphatase
KM392_26555	COG4821	SIS domain
KM392_26565	COG3343	RNA polymerase activity
KM392_26575	COG1960	acyl-CoA dehydrogenase activity
KM392_26580	COG1960	acyl-CoA dehydrogenase activity
KM392_26585	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM392_26590	COG0183	Belongs to the thiolase family
KM392_26595	COG0247	lactate metabolic process
KM392_26595	COG2181	nitrate reductase activity
KM392_26600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM392_26610	COG3300	MHYT domain
KM392_26610	COG5001	Diguanylate cyclase
KM392_26630	COG2197	response regulator
KM392_26635	COG4585	Histidine kinase
KM392_26640	COG0842	Transport permease protein
KM392_26645	COG1131	(ABC) transporter
KM392_26650	COG0024	Methionine aminopeptidase
KM392_26660	COG2234	aminopeptidase activity
KM392_26680	COG1595	DNA-templated transcription, initiation
KM392_26685	COG0018	arginyl-trna synthetase
KM392_26690	COG4506	Protein conserved in bacteria
KM392_26695	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM392_26710	COG0010	Belongs to the arginase family
KM392_26720	COG2814	Major facilitator Superfamily
KM392_26725	COG0789	Transcriptional regulator
KM392_26730	COG0584	glycerophosphoryl diester phosphodiesterase
KM392_26735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM392_26745	COG1994	Peptidase M50
KM392_26755	COG1078	dGTPase activity
KM392_26760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM392_26765	COG1120	ATPase activity
KM392_26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_26775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM392_26795	COG0095	Lipoate-protein ligase
KM392_26800	COG0280	phosphate acetyltransferase
KM392_26815	COG3773	Cell wall hydrolase
KM392_26825	COG2363	Small membrane protein
KM392_26835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM392_26840	COG2233	PERMEase
KM392_26845	COG0561	phosphatase activity
KM392_26850	COG2814	Major facilitator Superfamily
KM392_26860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM392_26865	COG1131	(ABC) transporter
KM392_26870	COG2755	lipolytic protein G-D-S-L family
KM392_26875	COG1609	Transcriptional regulator
KM392_26885	COG0460	homoserine dehydrogenase
KM392_26895	COG2873	o-acetylhomoserine
KM392_26905	COG1011	Hydrolase
KM392_26910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM392_26920	COG2197	response regulator
KM392_26930	COG0351	phosphomethylpyrimidine kinase
KM392_26935	COG3706	GGDEF domain
KM392_26940	COG2879	small protein
KM392_26945	COG1966	Carbon starvation protein
KM392_26950	COG3279	Response regulator of the LytR AlgR family
KM392_26955	COG0477	Major facilitator Superfamily
KM392_26990	COG1607	acyl-coa hydrolase
KM392_27005	COG0488	(ABC) transporter
KM392_27025	COG0463	Glycosyl transferase, family 2
KM392_27030	COG1309	transcriptional regulator
KM392_27035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM392_27040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM392_27040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM392_27045	COG0628	permease
KM392_27060	COG3279	Response regulator of the LytR AlgR family
KM392_27065	COG3275	phosphorelay sensor kinase activity
KM392_27070	COG2814	Major facilitator Superfamily
KM392_27075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM392_27080	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM392_27085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM392_27105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM392_27110	COG1272	protein, Hemolysin III
KM392_27135	COG1164	Oligoendopeptidase f
KM392_27155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM392_27160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM392_27165	COG4853	Protein conserved in bacteria
KM392_27170	COG4863	YycH protein
KM392_27175	COG5002	protein histidine kinase activity
KM392_27180	COG0745	RESPONSE REGULATOR receiver
KM392_27210	COG0305	Participates in initiation and elongation during chromosome replication
KM392_27220	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM392_27225	COG4241	membrane
KM392_27235	COG0629	single-stranded DNA binding
KM392_27245	COG0012	GTP binding
KM392_27250	COG4481	Protein conserved in bacteria
KM392_27255	COG0668	transmembrane transport
KM392_27265	COG1475	DNA binding
KM392_27270	COG1192	Involved in chromosome partitioning
KM392_27295	COG1847	R3H domain protein
KM392_27300	COG0706	membrane insertase activity
KM392_27310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM392_27365	COG3344	reverse transcriptase
KM392_27445	COG3344	reverse transcriptase
KM392_27640	COG4962	Type ii secretion system protein e
KM392_27780	COG2311	Membrane
KM392_27800	COG4196	transglutaminase domain protein
KM392_27805	COG0671	phosphoesterase, PA-phosphatase related
KM392_27820	COG1215	transferase activity, transferring glycosyl groups
KM392_27825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM392_27830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM392_27995	COG2002	toxin-antitoxin pair type II binding
KM392_28005	COG4974	Belongs to the 'phage' integrase family
KM392_28060	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM392_28070	COG4974	Belongs to the 'phage' integrase family
KM392_28095	COG0457	Tetratricopeptide repeat
KM392_28365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM392_28370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM392_28425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM392_28435	COG4166	transmembrane transport
KM392_28475	COG1280	lysine exporter protein (LysE YggA)
KM392_28500	COG0681	Belongs to the peptidase S26 family
KM392_28575	COG1309	transcriptional regulator
KM392_28580	COG1683	Conserved Protein
KM392_28620	COG1192	Involved in chromosome partitioning