locus-tag	class	description
TD69_00010	COG0592	DNA-directed DNA polymerase activity
TD69_00015	COG2501	S4 domain
TD69_00025	COG0187	DNA topoisomerase II activity
TD69_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD69_00065	COG0516	GMP reductase activity
TD69_00065	COG0517	IMP dehydrogenase activity
TD69_00070	COG1686	Belongs to the peptidase S11 family
TD69_00100	COG1428	Deoxynucleoside kinase
TD69_00105	COG1428	Deoxynucleoside kinase
TD69_00110	COG1335	isochorismatase
TD69_00120	COG0590	tRNA wobble adenosine to inosine editing
TD69_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TD69_00180	COG1982	Orn Lys Arg decarboxylase major
TD69_00190	COG0470	DNA polymerase III
TD69_00195	COG1774	PSP1 C-terminal conserved region
TD69_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TD69_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TD69_00220	COG2002	toxin-antitoxin pair type II binding
TD69_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_00230	COG0084	hydrolase, TatD family'
TD69_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD69_00250	COG4466	Protein conserved in bacteria
TD69_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TD69_00270	COG0251	oxidation-reduction process
TD69_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TD69_00290	COG0193	aminoacyl-tRNA hydrolase activity
TD69_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TD69_00305	COG2002	toxin-antitoxin pair type II binding
TD69_00310	COG2244	polysaccharide biosynthetic process
TD69_00315	COG3956	TIGRFAM MazG family protein
TD69_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TD69_00340	COG1098	S1 RNA binding domain
TD69_00355	COG2208	phosphoserine phosphatase activity
TD69_00360	COG0037	tRNA processing
TD69_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TD69_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD69_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TD69_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
TD69_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD69_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TD69_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TD69_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TD69_00420	COG1396	sequence-specific DNA binding
TD69_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD69_00455	COG3880	PFAM UvrB UvrC protein
TD69_00465	COG0542	response to heat
TD69_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TD69_00480	COG4956	integral membrane protein (PIN domain superfamily)
TD69_00500	COG1045	serine acetyltransferase
TD69_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD69_00520	COG3688	RNA-binding protein containing a PIN domain
TD69_00530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TD69_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD69_00540	COG0250	Participates in transcription elongation, termination and antitermination
TD69_00565	COG2813	Specifically methylates the guanine in position
TD69_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TD69_00580	COG1358	cellular component organization or biogenesis
TD69_00685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TD69_00710	COG0201	protein transport
TD69_00720	COG0024	Methionine aminopeptidase
TD69_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TD69_00760	COG1122	ATPase activity
TD69_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD69_00770	COG0101	tRNA pseudouridine synthase activity
TD69_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD69_00795	COG0489	protein tyrosine kinase activity
TD69_00805	COG2194	sulfuric ester hydrolase activity
TD69_00810	COG0726	polysaccharide deacetylase
TD69_00895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TD69_00900	COG4856	YbbR-like protein
TD69_00915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TD69_00920	COG0596	Alpha beta hydrolase
TD69_00940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TD69_00945	COG4946	Tricorn protease homolog
TD69_00945	COG1506	peptidase
TD69_00945	COG0823	Involved in the tonB-independent uptake of proteins
TD69_00980	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_00985	COG2011	ABC-type metal ion transport system permease component
TD69_00990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TD69_00995	COG1464	Belongs to the NlpA lipoprotein family
TD69_01010	COG0277	FAD linked oxidase domain protein
TD69_01015	COG2271	Major facilitator Superfamily
TD69_01025	COG2814	Major facilitator Superfamily
TD69_01040	COG0601	transmembrane transport
TD69_01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD69_01050	COG0444	Belongs to the ABC transporter superfamily
TD69_01055	COG4608	Belongs to the ABC transporter superfamily
TD69_01060	COG4166	transmembrane transport
TD69_01070	COG2207	Transcriptional regulator
TD69_01085	COG4166	transmembrane transport
TD69_01090	COG4166	transmembrane transport
TD69_01095	COG0656	L-ascorbic acid biosynthetic process
TD69_01100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD69_01115	COG4975	Glucose uptake
TD69_01120	COG4149	molybdate abc transporter
TD69_01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
TD69_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
TD69_01135	COG1910	domain protein
TD69_01150	COG0583	DNA-binding transcription factor activity
TD69_01155	COG0697	spore germination
TD69_01165	COG0204	Acyl-transferase
TD69_01175	COG1609	Transcriptional regulator
TD69_01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_01200	COG0084	hydrolase, TatD family'
TD69_01205	COG5298	Protein conserved in bacteria
TD69_01230	COG0488	(ABC) transporter
TD69_01245	COG0747	negative chemotaxis
TD69_01250	COG0601	transmembrane transport
TD69_01260	COG0444	Belongs to the ABC transporter superfamily
TD69_01265	COG4608	Belongs to the ABC transporter superfamily
TD69_01290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
TD69_01295	COG0179	Fumarylacetoacetate (FAA) hydrolase
TD69_01305	COG2814	Major facilitator Superfamily
TD69_01320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TD69_01330	COG4294	response to UV
TD69_01335	COG0705	Rhomboid family
TD69_01335	COG0457	Tetratricopeptide repeat
TD69_01345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TD69_01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD69_01355	COG0864	Transcriptional regulator
TD69_01360	COG2337	Toxic component of a toxin-antitoxin (TA) module
TD69_01365	COG2183	response to ionizing radiation
TD69_01460	COG0802	atpase or kinase
TD69_01465	COG1214	PFAM Peptidase M22, glycoprotease
TD69_01470	COG0456	acetyltransferase
TD69_01475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TD69_01480	COG0488	(ABC) transporter
TD69_01495	COG1266	CAAX protease self-immunity
TD69_01515	COG2252	PERMEase
TD69_01525	COG5002	protein histidine kinase activity
TD69_01555	COG2226	methyltransferase
TD69_01595	COG1968	undecaprenyl-diphosphatase activity
TD69_01610	COG2205	protein histidine kinase activity
TD69_01615	COG0745	RESPONSE REGULATOR receiver
TD69_01635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TD69_01640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TD69_01645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TD69_01655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TD69_01670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TD69_01680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TD69_01690	COG0151	Belongs to the GarS family
TD69_01715	COG0210	DNA helicase
TD69_01725	COG4851	CamS sex pheromone cAM373 precursor
TD69_01745	COG1335	isochorismatase
TD69_01750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TD69_01755	COG2011	ABC-type metal ion transport system permease component
TD69_01760	COG1464	Belongs to the NlpA lipoprotein family
TD69_01780	COG1846	Transcriptional regulator
TD69_01805	COG1597	lipid kinase activity
TD69_01810	COG0546	phosphoglycolate phosphatase activity
TD69_01815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TD69_01825	COG1012	belongs to the aldehyde dehydrogenase family
TD69_01830	COG2076	Multidrug Resistance protein
TD69_01835	COG2309	aminopeptidase activity
TD69_01850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_01855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD69_01860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD69_01870	COG4807	Protein conserved in bacteria
TD69_01900	COG1473	amidohydrolase
TD69_01915	COG0450	alkyl hydroperoxide reductase
TD69_01920	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
TD69_01930	COG0235	Class ii aldolase
TD69_01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_01940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_01945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_01965	COG0166	Belongs to the GPI family
TD69_02000	COG5002	protein histidine kinase activity
TD69_02020	COG3541	Predicted nucleotidyltransferase
TD69_02025	COG2814	Major facilitator Superfamily
TD69_02030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD69_02030	COG0723	plastoquinol--plastocyanin reductase activity
TD69_02040	COG0765	amino acid transport
TD69_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD69_02060	COG0840	transmembrane signaling receptor activity
TD69_02065	COG0840	transmembrane signaling receptor activity
TD69_02070	COG0366	Alpha amylase catalytic
TD69_02075	COG2190	(PTS) system
TD69_02075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_02075	COG1263	PTS System
TD69_02105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
TD69_02120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD69_02130	COG1116	anion transmembrane transporter activity
TD69_02135	COG0488	(ABC) transporter
TD69_02180	COG2270	Major facilitator Superfamily
TD69_02195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TD69_02210	COG2310	stress, protein
TD69_02215	COG2310	stress, protein
TD69_02220	COG2310	stress, protein
TD69_02225	COG0861	Integral membrane protein TerC family
TD69_02235	COG3853	Toxic anion resistance protein (TelA)
TD69_02250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD69_02260	COG1295	ribonuclease BN
TD69_02265	COG2217	Heavy metal translocating P-type atpase
TD69_02270	COG0697	spore germination
TD69_02290	COG0586	Pfam SNARE associated Golgi protein
TD69_02305	COG3871	stress protein (general stress protein 26)
TD69_02310	COG0387	Pfam Sodium calcium exchanger
TD69_02320	COG0535	radical SAM domain protein
TD69_02345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TD69_02350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD69_02355	COG0582	viral genome integration into host DNA
TD69_02360	COG1396	sequence-specific DNA binding
TD69_02375	COG1396	sequence-specific DNA binding
TD69_02410	COG1484	DNA-dependent DNA replication
TD69_02505	COG0582	viral genome integration into host DNA
TD69_02510	COG0582	viral genome integration into host DNA
TD69_02635	COG0101	tRNA pseudouridine synthase activity
TD69_02645	COG3829	transcription factor binding
TD69_02655	COG0833	amino acid
TD69_02660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD69_02690	COG2066	Belongs to the glutaminase family
TD69_02695	COG1263	PTS System
TD69_02695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_02700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD69_02715	COG0463	Glycosyl transferase, family 2
TD69_02730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TD69_02730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD69_02750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TD69_02770	COG1228	amidohydrolase
TD69_02775	COG1090	epimerase
TD69_02805	COG1988	membrane-bound metal-dependent
TD69_02810	COG1194	a g-specific adenine glycosylase
TD69_02835	COG1132	(ABC) transporter
TD69_02840	COG4129	membrane
TD69_02845	COG0070	glutamate synthase
TD69_02845	COG0067	glutamate synthase
TD69_02845	COG0069	glutamate synthase activity
TD69_02855	COG4555	ABC transporter
TD69_02875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TD69_02880	COG0735	belongs to the Fur family
TD69_02995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TD69_03000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TD69_03010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TD69_03020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TD69_03035	COG2766	serine protein kinase
TD69_03060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TD69_03070	COG1585	Membrane protein implicated in regulation of membrane protease activity
TD69_03075	COG2268	Band 7 protein
TD69_03085	COG3290	protein histidine kinase activity
TD69_03095	COG2851	Citrate transporter
TD69_03115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
TD69_03120	COG3842	ATPase activity
TD69_03125	COG1175	transmembrane transport
TD69_03130	COG0395	ABC-type sugar transport system, permease component
TD69_03140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TD69_03145	COG0745	RESPONSE REGULATOR receiver
TD69_03150	COG5002	protein histidine kinase activity
TD69_03160	COG4990	cell redox homeostasis
TD69_03170	COG3290	protein histidine kinase activity
TD69_03175	COG4565	transcriptional regulatory protein
TD69_03180	COG3493	citrate carrier protein
TD69_03185	COG0281	malic enzyme
TD69_03200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_03210	COG5002	protein histidine kinase activity
TD69_03215	COG0745	RESPONSE REGULATOR receiver
TD69_03225	COG0454	-acetyltransferase
TD69_03225	COG0456	acetyltransferase
TD69_03230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TD69_03235	COG3383	formate dehydrogenase (NAD+) activity
TD69_03240	COG2427	Protein of unknown function (DUF1641)
TD69_03255	COG0531	amino acid
TD69_03260	COG0640	Transcriptional regulator
TD69_03265	COG2217	Heavy metal translocating P-type atpase
TD69_03270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TD69_03280	COG3227	Zinc metalloprotease (Elastase)
TD69_03300	COG2720	vancomycin resistance protein
TD69_03305	COG1316	TRANSCRIPTIONal
TD69_03310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_03315	COG0346	lactoylglutathione lyase activity
TD69_03320	COG1253	flavin adenine dinucleotide binding
TD69_03325	COG1027	Aspartate ammonia-lyase
TD69_03330	COG1620	l-lactate permease
TD69_03345	COG3104	oligopeptide transport
TD69_03350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_03355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_03360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_03370	COG2226	methyltransferase
TD69_03375	COG0156	8-amino-7-oxononanoate synthase activity
TD69_03380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD69_03390	COG4548	von Willebrand factor, type A
TD69_03395	COG0714	Associated with various cellular activities
TD69_03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD69_03420	COG0531	amino acid
TD69_03425	COG2188	Transcriptional regulator
TD69_03430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_03430	COG1263	PTS System
TD69_03435	COG0366	Alpha amylase catalytic
TD69_03450	COG0697	spore germination
TD69_03460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD69_03465	COG1115	amino acid carrier protein
TD69_03470	COG1126	abc transporter atp-binding protein
TD69_03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD69_03480	COG0765	amino acid transport
TD69_03485	COG0765	amino acid transport
TD69_03490	COG0833	amino acid
TD69_03515	COG2378	regulation of single-species biofilm formation
TD69_03520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TD69_03525	COG5002	protein histidine kinase activity
TD69_03540	COG0659	secondary active sulfate transmembrane transporter activity
TD69_03555	COG0747	negative chemotaxis
TD69_03565	COG0601	transmembrane transport
TD69_03570	COG4608	Belongs to the ABC transporter superfamily
TD69_03580	COG2271	Major facilitator Superfamily
TD69_03585	COG1846	Transcriptional regulator
TD69_03590	COG0477	Major facilitator Superfamily
TD69_03595	COG0477	Major facilitator Superfamily
TD69_03600	COG1609	Transcriptional regulator
TD69_03605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD69_03615	COG1129	ABC transporter
TD69_03620	COG1172	Belongs to the binding-protein-dependent transport system permease family
TD69_03625	COG1879	ABC-type sugar transport system periplasmic component
TD69_03630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TD69_03650	COG1063	alcohol dehydrogenase
TD69_03665	COG3568	Endonuclease Exonuclease Phosphatase
TD69_03690	COG1968	undecaprenyl-diphosphatase activity
TD69_03695	COG0840	transmembrane signaling receptor activity
TD69_03700	COG3584	3D domain protein
TD69_03700	COG1388	LysM domain
TD69_03705	COG1476	TRANSCRIPTIONal
TD69_03720	COG3104	oligopeptide transport
TD69_03725	COG1114	Component of the transport system for branched-chain amino acids
TD69_03740	COG1113	amino acid transport
TD69_03745	COG2252	PERMEase
TD69_03770	COG0569	domain protein
TD69_03770	COG0475	glutathione-regulated potassium exporter activity
TD69_03785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TD69_03790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TD69_03795	COG0833	amino acid
TD69_03800	COG4990	cell redox homeostasis
TD69_03815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD69_03820	COG0697	spore germination
TD69_03825	COG0531	amino acid
TD69_03840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TD69_03845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TD69_03850	COG1918	ferrous iron import across plasma membrane
TD69_03850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TD69_03855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TD69_03860	COG0573	inorganic phosphate transmembrane transporter activity
TD69_03865	COG0581	inorganic phosphate transmembrane transporter activity
TD69_03875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TD69_03990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
TD69_04015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TD69_04020	COG1116	anion transmembrane transporter activity
TD69_04025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD69_04030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD69_04035	COG0352	thiamine-phosphate diphosphorylase activity
TD69_04040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD69_04045	COG2104	thiamine diphosphate biosynthetic process
TD69_04055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD69_04060	COG0351	phosphomethylpyrimidine kinase
TD69_04100	COG2205	protein histidine kinase activity
TD69_04105	COG2814	Major facilitator Superfamily
TD69_04110	COG1846	Transcriptional regulator
TD69_04125	COG2252	PERMEase
TD69_04130	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_04145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD69_04150	COG1621	beta-fructofuranosidase activity
TD69_04155	COG1263	PTS System
TD69_04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_04160	COG1609	Transcriptional regulator
TD69_04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD69_04175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TD69_04215	COG0778	Nitroreductase
TD69_04220	COG2719	SpoVR family
TD69_04245	COG0446	pyridine nucleotide-disulphide oxidoreductase
TD69_04250	COG1937	Protein conserved in bacteria
TD69_04255	COG0425	Belongs to the sulfur carrier protein TusA family
TD69_04255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_04260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_04265	COG0425	Belongs to the sulfur carrier protein TusA family
TD69_04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_04280	COG2210	Belongs to the sulfur carrier protein TusA family
TD69_04285	COG0730	response to heat
TD69_04295	COG1316	TRANSCRIPTIONal
TD69_04300	COG0604	alcohol dehydrogenase
TD69_04305	COG1283	sodium-dependent phosphate transmembrane transporter activity
TD69_04320	COG3711	transcriptional antiterminator
TD69_04320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD69_04325	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD69_04330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD69_04350	COG1388	LysM domain
TD69_04350	COG3584	3D domain protein
TD69_04355	COG0577	efflux transmembrane transporter activity
TD69_04360	COG1136	(ABC) transporter
TD69_04370	COG5522	Integral membrane protein (intg_mem_TP0381)
TD69_04385	COG1114	Component of the transport system for branched-chain amino acids
TD69_04390	COG3546	catalase activity
TD69_04425	COG0586	Pfam SNARE associated Golgi protein
TD69_04460	COG0531	amino acid
TD69_04465	COG0475	glutathione-regulated potassium exporter activity
TD69_04475	COG1737	Transcriptional regulator
TD69_04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_04485	COG1263	PTS System
TD69_04495	COG2259	Doxx family
TD69_04510	COG0697	spore germination
TD69_04515	COG1522	sequence-specific DNA binding
TD69_04525	COG2076	Multidrug Resistance protein
TD69_04530	COG2076	Multidrug Resistance protein
TD69_04535	COG1309	transcriptional regulator
TD69_04540	COG2814	Major facilitator Superfamily
TD69_04545	COG1733	regulation of RNA biosynthetic process
TD69_04555	COG2249	NAD(P)H dehydrogenase (quinone) activity
TD69_04560	COG4533	DNA binding
TD69_04565	COG2211	Major facilitator Superfamily
TD69_04575	COG0693	protein deglycase activity
TD69_04580	COG0753	catalase activity
TD69_04580	COG0693	protein deglycase activity
TD69_04590	COG0531	amino acid
TD69_04595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TD69_04605	COG1012	belongs to the aldehyde dehydrogenase family
TD69_04615	COG1132	(ABC) transporter
TD69_04625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD69_04630	COG0765	amino acid transport
TD69_04635	COG1126	abc transporter atp-binding protein
TD69_04650	COG0189	ligase activity
TD69_04680	COG0028	Belongs to the TPP enzyme family
TD69_04685	COG3527	Alpha-acetolactate decarboxylase
TD69_04700	COG0561	phosphatase activity
TD69_04715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD69_04730	COG0659	secondary active sulfate transmembrane transporter activity
TD69_04750	COG0653	protein targeting
TD69_04755	COG2244	polysaccharide biosynthetic process
TD69_04765	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD69_04770	COG4196	transglutaminase domain protein
TD69_04785	COG1696	Membrane protein involved in D-alanine export
TD69_04800	COG1024	Enoyl-CoA hydratase
TD69_04820	COG1363	Peptidase, m42
TD69_04840	COG3938	Belongs to the proline racemase family
TD69_04880	COG0601	transmembrane transport
TD69_04885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD69_04895	COG4608	Belongs to the ABC transporter superfamily
TD69_04925	COG0477	Major facilitator Superfamily
TD69_04930	COG3290	protein histidine kinase activity
TD69_04935	COG4565	transcriptional regulatory protein
TD69_04940	COG3181	Tripartite tricarboxylate transporter family receptor
TD69_04970	COG4978	Transcriptional regulator
TD69_04970	COG0789	Transcriptional regulator
TD69_04985	COG0305	Participates in initiation and elongation during chromosome replication
TD69_05025	COG0477	Major facilitator Superfamily
TD69_05075	COG3320	Male sterility
TD69_05075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD69_05100	COG1183	phosphatidylcholine synthase activity
TD69_05120	COG2376	Dihydroxyacetone kinase
TD69_05130	COG2376	Dihydroxyacetone kinase
TD69_05135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD69_05140	COG1959	2 iron, 2 sulfur cluster binding
TD69_05165	COG3437	response regulator, receiver
TD69_05165	COG2770	Histidine kinase
TD69_05215	COG3237	CsbD-like
TD69_05240	COG1191	sigma factor activity
TD69_05250	COG2208	phosphoserine phosphatase activity
TD69_05255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TD69_05260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD69_05260	COG2198	Histidine kinase
TD69_05260	COG0784	Response regulator, receiver
TD69_05260	COG2205	protein histidine kinase activity
TD69_05320	COG0420	3'-5' exonuclease activity
TD69_05325	COG4717	serine-type aminopeptidase activity
TD69_05345	COG1309	transcriptional regulator
TD69_05350	COG2814	Major facilitator Superfamily
TD69_05355	COG0346	lactoylglutathione lyase activity
TD69_05360	COG0346	lactoylglutathione lyase activity
TD69_05365	COG0457	Tetratricopeptide repeat
TD69_05370	COG2267	carboxylic ester hydrolase activity
TD69_05390	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
TD69_05395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TD69_05405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TD69_05445	COG0477	Major facilitator Superfamily
TD69_05450	COG0477	Major facilitator Superfamily
TD69_05460	COG3973	AAA domain
TD69_05465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD69_05490	COG4980	gas vesicle protein
TD69_05495	COG0537	adenosine 5'-monophosphoramidase activity
TD69_05500	COG1131	(ABC) transporter
TD69_05505	COG4473	ABC transporter
TD69_05515	COG1309	transcriptional regulator
TD69_05525	COG3402	PFAM membrane-flanked domain
TD69_05535	COG3428	Bacterial PH domain
TD69_05580	COG3402	PFAM membrane-flanked domain
TD69_05585	COG3428	Bacterial PH domain
TD69_05590	COG2329	Antibiotic biosynthesis monooxygenase
TD69_05595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD69_05600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TD69_05645	COG1309	transcriptional regulator
TD69_05650	COG1511	domain protein
TD69_05675	COG1609	Transcriptional regulator
TD69_05685	COG1234	tRNA 3'-trailer cleavage
TD69_05690	COG0095	Lipoate-protein ligase
TD69_05700	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_05730	COG3209	COG3209 Rhs family protein
TD69_05775	COG1408	metallophosphoesterase
TD69_05780	COG1078	dGTPase activity
TD69_05790	COG1595	DNA-templated transcription, initiation
TD69_05795	COG3708	Transcriptional regulator
TD69_05795	COG2207	Transcriptional regulator
TD69_05810	COG2205	protein histidine kinase activity
TD69_05815	COG0745	RESPONSE REGULATOR receiver
TD69_05840	COG0501	Belongs to the peptidase M48B family
TD69_05845	COG0840	transmembrane signaling receptor activity
TD69_05850	COG0697	spore germination
TD69_05865	COG0497	DNA recombination
TD69_05870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TD69_05875	COG2224	Isocitrate lyase
TD69_05885	COG1278	Cold shock
TD69_05900	COG4903	ComK protein
TD69_05905	COG0398	Pfam SNARE associated Golgi protein
TD69_05915	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TD69_05920	COG1074	ATP-dependent DNA helicase activity
TD69_05965	COG0179	Fumarylacetoacetate (FAA) hydrolase
TD69_05990	COG0367	asparagine synthase
TD69_06000	COG0753	catalase activity
TD69_06030	COG2996	Protein conserved in bacteria
TD69_06040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD69_06050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_06065	COG0561	phosphatase activity
TD69_06080	COG0542	response to heat
TD69_06090	COG2267	carboxylic ester hydrolase activity
TD69_06105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD69_06115	COG5504	Zn-dependent protease
TD69_06125	COG0180	Tryptophanyl-tRNA synthetase
TD69_06135	COG4166	transmembrane transport
TD69_06140	COG0601	transmembrane transport
TD69_06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD69_06150	COG0444	Belongs to the ABC transporter superfamily
TD69_06155	COG4608	Belongs to the ABC transporter superfamily
TD69_06160	COG0534	Mate efflux family protein
TD69_06165	COG4166	transmembrane transport
TD69_06180	COG1393	Belongs to the ArsC family
TD69_06185	COG0861	Integral membrane protein TerC family
TD69_06190	COG4862	establishment of competence for transformation
TD69_06195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD69_06205	COG1164	Oligoendopeptidase f
TD69_06220	COG2346	COG2346, Truncated hemoglobins
TD69_06225	COG4116	CYTH
TD69_06235	COG2357	RelA SpoT domain protein
TD69_06240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD69_06245	COG0564	pseudouridine synthase activity
TD69_06260	COG0772	Belongs to the SEDS family
TD69_06265	COG1216	Glycosyl transferase, family 2
TD69_06285	COG0463	Glycosyl transferase, family 2
TD69_06285	COG0457	Tetratricopeptide repeat
TD69_06305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TD69_06320	COG1091	dTDP-4-dehydrorhamnose reductase activity
TD69_06365	COG2153	protein acetylation
TD69_06370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TD69_06375	COG2382	esterase
TD69_06390	COG5492	domain, Protein
TD69_06395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD69_06410	COG0512	Glutamine amidotransferase of anthranilate synthase
TD69_06410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TD69_06445	COG1620	l-lactate permease
TD69_06450	COG5634	Uncharacterized conserved protein (DUF2278)
TD69_06500	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD69_06510	COG1476	TRANSCRIPTIONal
TD69_06570	COG2226	methyltransferase
TD69_06580	COG1686	Belongs to the peptidase S11 family
TD69_06585	COG0681	Belongs to the peptidase S26 family
TD69_06620	COG1012	belongs to the aldehyde dehydrogenase family
TD69_06625	COG3842	ATPase activity
TD69_06630	COG1176	ABC-type spermidine putrescine transport system, permease component I
TD69_06635	COG1177	transmembrane transport
TD69_06640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TD69_06650	COG2409	Drug exporters of the RND superfamily
TD69_06660	COG0564	pseudouridine synthase activity
TD69_06670	COG2340	Cysteine-rich secretory protein family
TD69_06675	COG0247	lactate metabolic process
TD69_06680	COG0277	FAD linked oxidase domain protein
TD69_06685	COG3835	regulator
TD69_06695	COG0745	RESPONSE REGULATOR receiver
TD69_06700	COG5002	protein histidine kinase activity
TD69_06705	COG2186	Transcriptional regulator
TD69_06725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TD69_06735	COG2116	formate transmembrane transporter activity
TD69_06740	COG0861	Integral membrane protein TerC family
TD69_06745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD69_06755	COG2030	dehydratase
TD69_06775	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_06780	COG3243	poly(R)-hydroxyalkanoic acid synthase
TD69_06790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD69_06805	COG1840	ABC-type Fe3 transport system, periplasmic component
TD69_06820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TD69_06835	COG1349	DNA-binding transcription factor activity
TD69_06860	COG2861	carbohydrate metabolic process
TD69_06870	COG3852	Histidine kinase
TD69_06875	COG1846	Transcriptional regulator
TD69_06885	COG2318	DinB family
TD69_06895	COG5002	protein histidine kinase activity
TD69_06905	COG0720	synthase
TD69_06920	COG4873	Protein conserved in bacteria
TD69_06955	COG1780	Probably involved in ribonucleotide reductase function
TD69_06975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD69_06980	COG1725	Transcriptional regulator
TD69_06985	COG1131	(ABC) transporter
TD69_06995	COG1131	(ABC) transporter
TD69_07000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD69_07015	COG1522	sequence-specific DNA binding
TD69_07025	COG1335	isochorismatase
TD69_07035	COG1619	proteins homologs of microcin C7 resistance protein MccF
TD69_07040	COG2070	2-Nitropropane dioxygenase
TD69_07045	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
TD69_07055	COG1696	Membrane protein involved in D-alanine export
TD69_07080	COG0716	FMN binding
TD69_07095	COG3173	Aminoglycoside phosphotransferase
TD69_07115	COG0534	Mate efflux family protein
TD69_07120	COG1968	undecaprenyl-diphosphatase activity
TD69_07135	COG1846	Transcriptional regulator
TD69_07145	COG1301	dicarboxylic acid transport
TD69_07150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD69_07155	COG4709	membrane
TD69_07160	COG3874	Sporulation protein YtfJ
TD69_07190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD69_07195	COG0028	Belongs to the TPP enzyme family
TD69_07200	COG0440	acetolactate synthase activity
TD69_07205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TD69_07215	COG0473	3-isopropylmalate dehydrogenase activity
TD69_07240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TD69_07275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD69_07290	COG1183	phosphatidylcholine synthase activity
TD69_07295	COG1368	sulfuric ester hydrolase activity
TD69_07305	COG0019	diaminopimelate decarboxylase activity
TD69_07325	COG0529	Catalyzes the synthesis of activated sulfate
TD69_07330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD69_07350	COG1648	precorrin-2 dehydrogenase activity
TD69_07360	COG0733	neurotransmitter:sodium symporter activity
TD69_07380	COG1757	Na H antiporter
TD69_07395	COG4758	membrane
TD69_07400	COG4585	Histidine kinase
TD69_07405	COG2197	response regulator
TD69_07415	COG1114	Component of the transport system for branched-chain amino acids
TD69_07425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TD69_07450	COG1017	nitric oxide dioxygenase activity
TD69_07450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TD69_07470	COG0730	response to heat
TD69_07475	COG0306	phosphate transporter
TD69_07480	COG1392	Phosphate transport regulator
TD69_07485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD69_07500	COG3852	Histidine kinase
TD69_07505	COG1801	Protein of unknown function DUF72
TD69_07515	COG0582	viral genome integration into host DNA
TD69_07520	COG5002	protein histidine kinase activity
TD69_07540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TD69_07540	COG0392	lysyltransferase activity
TD69_07555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD69_07560	COG1686	Belongs to the peptidase S11 family
TD69_07565	COG2715	membrane protein required for spore maturation
TD69_07570	COG0700	Nucleoside recognition
TD69_07575	COG1187	pseudouridine synthase activity
TD69_07585	COG1333	cytochrome c biogenesis protein
TD69_07590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD69_07595	COG0745	RESPONSE REGULATOR receiver
TD69_07600	COG5002	protein histidine kinase activity
TD69_07605	COG2096	Adenosyltransferase
TD69_07620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
TD69_07625	COG1141	Ferredoxin
TD69_07630	COG4955	Helix-turn-helix domain
TD69_07635	COG0514	ATP-dependent DNA helicase (RecQ)
TD69_07640	COG1266	CAAX protease self-immunity
TD69_07660	COG4862	establishment of competence for transformation
TD69_07665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD69_07685	COG0492	ferredoxin-NADP+ reductase activity
TD69_07690	COG0252	asparaginase activity
TD69_07760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD69_07775	COG0142	geranyltranstransferase activity
TD69_07785	COG0142	geranyltranstransferase activity
TD69_07790	COG0105	UTP biosynthetic process
TD69_07805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TD69_07810	COG0457	Tetratricopeptide repeat
TD69_07830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TD69_07840	COG4347	Protein of unknown function (DUF1405)
TD69_07855	COG2738	Putative neutral zinc metallopeptidase
TD69_07865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_07870	COG1694	Mazg nucleotide pyrophosphohydrolase
TD69_07885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD69_07890	COG0438	transferase activity, transferring glycosyl groups
TD69_07930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TD69_07930	COG1199	ATP-dependent helicase activity
TD69_07950	COG3935	DnaD domain protein
TD69_07955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TD69_07965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD69_07965	COG4499	WXG100 protein secretion system (Wss), protein YukC
TD69_08005	COG4474	Belongs to the UPF0398 family
TD69_08015	COG0116	Belongs to the methyltransferase superfamily
TD69_08025	COG1199	ATP-dependent helicase activity
TD69_08030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TD69_08040	COG3173	Aminoglycoside phosphotransferase
TD69_08045	COG0024	Methionine aminopeptidase
TD69_08055	COG2233	PERMEase
TD69_08060	COG2311	Membrane
TD69_08065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD69_08075	COG0456	acetyltransferase
TD69_08100	COG0754	glutathionylspermidine amidase activity
TD69_08115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD69_08140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TD69_08155	COG1215	transferase activity, transferring glycosyl groups
TD69_08175	COG0454	-acetyltransferase
TD69_08195	COG0328	RNA-DNA hybrid ribonuclease activity
TD69_08235	COG1280	lysine exporter protein (LysE YggA)
TD69_08250	COG3162	membrane
TD69_08255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD69_08260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD69_08270	COG0475	glutathione-regulated potassium exporter activity
TD69_08280	COG4978	Transcriptional regulator
TD69_08280	COG0789	Transcriptional regulator
TD69_08290	COG2323	membrane
TD69_08295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TD69_08350	COG1923	regulation of RNA biosynthetic process
TD69_08360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD69_08365	COG1360	Flagellar Motor Protein
TD69_08370	COG2201	protein-glutamate methylesterase activity
TD69_08380	COG1776	CheC inhibitor of MCP methylation
TD69_08380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD69_08395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TD69_08415	COG1256	bacterial-type flagellum assembly
TD69_08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD69_08445	COG1815	bacterial-type flagellum-dependent cell motility
TD69_08450	COG1558	bacterial-type flagellum-dependent cell motility
TD69_08455	COG1677	Flagellar hook-basal body complex protein FliE
TD69_08460	COG1766	The M ring may be actively involved in energy transduction
TD69_08470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD69_08480	COG1157	protein secretion by the type III secretion system
TD69_08530	COG0463	Glycosyl transferase, family 2
TD69_08560	COG0457	Tetratricopeptide repeat
TD69_08560	COG0463	Glycosyl transferase, family 2
TD69_08585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD69_08590	COG0741	lytic transglycosylase activity
TD69_08605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD69_08605	COG1776	CheC inhibitor of MCP methylation
TD69_08615	COG1338	Plays a role in the flagellum-specific transport system
TD69_08620	COG1987	bacterial-type flagellum assembly
TD69_08630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD69_08635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD69_08645	COG4786	Flagellar basal body rod
TD69_08650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TD69_08675	COG1309	transcriptional regulator
TD69_08695	COG2329	Antibiotic biosynthesis monooxygenase
TD69_08725	COG3842	ATPase activity
TD69_08730	COG0725	ABC transporter, periplasmic molybdate-binding protein
TD69_08735	COG1177	transmembrane transport
TD69_08740	COG1234	tRNA 3'-trailer cleavage
TD69_08765	COG1686	Belongs to the peptidase S11 family
TD69_08775	COG0406	alpha-ribazole phosphatase activity
TD69_08805	COG0367	asparagine synthase
TD69_08835	COG1802	Transcriptional regulator
TD69_08840	COG0697	spore germination
TD69_08845	COG0523	cobalamin synthesis protein
TD69_08850	COG0701	Predicted permease
TD69_08860	COG0438	transferase activity, transferring glycosyl groups
TD69_08860	COG1216	Glycosyl transferase, family 2
TD69_08865	COG1757	Na H antiporter
TD69_08870	COG0114	fumarate hydratase activity
TD69_08900	COG3340	Belongs to the peptidase S51 family
TD69_08920	COG0785	Cytochrome C biogenesis protein
TD69_08955	COG2733	membrane
TD69_08990	COG1131	(ABC) transporter
TD69_09005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD69_09010	COG0528	UMP kinase activity
TD69_09020	COG1027	Aspartate ammonia-lyase
TD69_09025	COG0281	malic enzyme
TD69_09030	COG4191	Histidine kinase
TD69_09035	COG0784	Response regulator, receiver
TD69_09040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD69_09100	COG1051	belongs to the nudix hydrolase family
TD69_09105	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD69_09130	COG1966	Carbon starvation protein
TD69_09145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_09155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TD69_09165	COG4166	transmembrane transport
TD69_09170	COG2223	nitrite transmembrane transporter activity
TD69_09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD69_09190	COG2244	polysaccharide biosynthetic process
TD69_09195	COG0733	neurotransmitter:sodium symporter activity
TD69_09205	COG5566	PFAM Mor transcription activator
TD69_09210	COG2323	membrane
TD69_09225	COG2084	Dehydrogenase
TD69_09240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TD69_09250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD69_09255	COG0028	Belongs to the TPP enzyme family
TD69_09260	COG0440	acetolactate synthase activity
TD69_09265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TD69_09275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TD69_09300	COG2814	Major facilitator Superfamily
TD69_09305	COG3384	dioxygenase
TD69_09315	COG3279	Response regulator of the LytR AlgR family
TD69_09320	COG0427	acetyl-CoA hydrolase
TD69_09340	COG1073	alpha beta
TD69_09345	COG4166	transmembrane transport
TD69_09375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_09395	COG1914	H( )-stimulated, divalent metal cation uptake system
TD69_09410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD69_09445	COG2390	Transcriptional regulator
TD69_09455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_09460	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TD69_09475	COG4224	UPF0291 protein
TD69_09495	COG0006	proline dipeptidase activity
TD69_09500	COG2132	Multicopper oxidase
TD69_09530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD69_09545	COG1276	copper resistance
TD69_09545	COG2372	response to copper ion
TD69_09550	COG4549	nuclear export factor GLE1
TD69_09560	COG0697	spore germination
TD69_09565	COG0583	DNA-binding transcription factor activity
TD69_09570	COG1959	2 iron, 2 sulfur cluster binding
TD69_09575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TD69_09580	COG0778	Nitroreductase
TD69_09595	COG0628	permease
TD69_09600	COG0039	L-malate dehydrogenase activity
TD69_09605	COG1231	oxidoreductase activity
TD69_09610	COG0523	cobalamin synthesis protein
TD69_09625	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_09630	COG2030	dehydratase
TD69_09635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_09645	COG0411	ABC transporter
TD69_09665	COG0583	DNA-binding transcription factor activity
TD69_09685	COG1846	Transcriptional regulator
TD69_09695	COG1271	oxidase subunit
TD69_09700	COG1294	oxidase, subunit
TD69_09705	COG4988	ABC transporter
TD69_09710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TD69_09730	COG1686	Belongs to the peptidase S11 family
TD69_09745	COG1388	LysM domain
TD69_09745	COG0791	NLP P60 protein
TD69_09755	COG1132	(ABC) transporter
TD69_09760	COG1132	(ABC) transporter
TD69_09765	COG0745	RESPONSE REGULATOR receiver
TD69_09770	COG5002	protein histidine kinase activity
TD69_09780	COG0300	oxidoreductase activity
TD69_09795	COG0726	polysaccharide deacetylase
TD69_09815	COG0460	homoserine dehydrogenase
TD69_09840	COG1316	TRANSCRIPTIONal
TD69_09850	COG0745	RESPONSE REGULATOR receiver
TD69_09855	COG5002	protein histidine kinase activity
TD69_09860	COG0726	polysaccharide deacetylase
TD69_09870	COG1285	pathogenesis
TD69_09875	COG1247	-acetyltransferase
TD69_09885	COG4264	IucA IucC family
TD69_09890	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_09905	COG1082	Xylose isomerase domain protein TIM barrel
TD69_09920	COG1279	arginine transmembrane transporter activity
TD69_09930	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD69_09970	COG2002	toxin-antitoxin pair type II binding
TD69_09975	COG1404	Belongs to the peptidase S8 family
TD69_09980	COG0640	Transcriptional regulator
TD69_09985	COG0667	Aldo Keto reductase
TD69_09990	COG2814	Major facilitator Superfamily
TD69_10015	COG0840	transmembrane signaling receptor activity
TD69_10035	COG3949	Membrane
TD69_10040	COG0783	Belongs to the Dps family
TD69_10055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD69_10065	COG1231	oxidoreductase activity
TD69_10075	COG4989	oxidoreductase activity
TD69_10080	COG0523	cobalamin synthesis protein
TD69_10085	COG0456	acetyltransferase
TD69_10150	COG3443	Belongs to the bacterial solute-binding protein 9 family
TD69_10150	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD69_10160	COG0702	epimerase
TD69_10170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD69_10180	COG4166	transmembrane transport
TD69_10195	COG0406	alpha-ribazole phosphatase activity
TD69_10205	COG5337	Spore coat protein CotH
TD69_10210	COG1051	belongs to the nudix hydrolase family
TD69_10215	COG0586	Pfam SNARE associated Golgi protein
TD69_10220	COG2244	polysaccharide biosynthetic process
TD69_10230	COG0701	Predicted permease
TD69_10235	COG3689	TIGRFAM TIGR03943 family protein
TD69_10240	COG1607	acyl-coa hydrolase
TD69_10245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD69_10260	COG0702	epimerase
TD69_10265	COG2839	Protein conserved in bacteria
TD69_10270	COG1253	flavin adenine dinucleotide binding
TD69_10285	COG1114	Component of the transport system for branched-chain amino acids
TD69_10290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_10310	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD69_10320	COG1876	peptidase activity
TD69_10330	COG0154	amidase activity
TD69_10335	COG2211	Major facilitator Superfamily
TD69_10355	COG0561	phosphatase activity
TD69_10365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD69_10385	COG1819	glycosyl
TD69_10390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_10420	COG0456	acetyltransferase
TD69_10470	COG3874	Sporulation protein YtfJ
TD69_10495	COG2226	methyltransferase
TD69_10515	COG1082	Xylose isomerase domain protein TIM barrel
TD69_10520	COG0346	lactoylglutathione lyase activity
TD69_10530	COG0604	alcohol dehydrogenase
TD69_10535	COG1595	DNA-templated transcription, initiation
TD69_10560	COG0386	Belongs to the glutathione peroxidase family
TD69_10565	COG1305	Transglutaminase-like
TD69_10570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
TD69_10575	COG0714	Associated with various cellular activities
TD69_10590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
TD69_10595	COG1140	nitrate reductase beta subunit
TD69_10600	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
TD69_10605	COG2181	nitrate reductase activity
TD69_10625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD69_10630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TD69_10635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD69_10640	COG0303	'Molybdopterin
TD69_10645	COG0314	molybdopterin synthase activity
TD69_10655	COG2223	nitrite transmembrane transporter activity
TD69_10670	COG1648	precorrin-2 dehydrogenase activity
TD69_10680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TD69_10680	COG1587	Uroporphyrinogen-III synthase
TD69_10685	COG2146	nitrite reductase [NAD(P)H] activity
TD69_10690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD69_10695	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
TD69_10730	COG2359	stage V sporulation protein S
TD69_10745	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD69_10760	COG1418	mRNA catabolic process
TD69_10765	COG0488	(ABC) transporter
TD69_10780	COG0629	single-stranded DNA binding
TD69_10795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TD69_10800	COG1413	lyase activity
TD69_10815	COG2136	Putative SAM-dependent methyltransferase
TD69_10815	COG2521	methyltransferase
TD69_10820	COG0018	arginyl-trna synthetase
TD69_10845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TD69_10860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TD69_10865	COG0017	Asparaginyl-tRNA synthetase
TD69_10885	COG1674	ftsk spoiiie
TD69_10980	COG1929	Belongs to the glycerate kinase type-1 family
TD69_10985	COG0471	metal ion transport
TD69_10990	COG0745	RESPONSE REGULATOR receiver
TD69_10995	COG3850	Histidine kinase
TD69_10995	COG5002	protein histidine kinase activity
TD69_11010	COG0733	neurotransmitter:sodium symporter activity
TD69_11035	COG2610	gluconate transmembrane transporter activity
TD69_11040	COG1454	alcohol dehydrogenase
TD69_11045	COG1794	racemase activity, acting on amino acids and derivatives
TD69_11055	COG0456	acetyltransferase
TD69_11070	COG1131	(ABC) transporter
TD69_11075	COG4473	ABC transporter
TD69_11085	COG0546	phosphoglycolate phosphatase activity
TD69_11105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD69_11120	COG0768	penicillin binding
TD69_11125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD69_11130	COG0204	Acyl-transferase
TD69_11135	COG1272	protein, Hemolysin III
TD69_11145	COG0805	protein transport
TD69_11155	COG1307	EDD domain protein, DegV family
TD69_11160	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TD69_11165	COG1999	signal sequence binding
TD69_11170	COG0071	Belongs to the small heat shock protein (HSP20) family
TD69_11175	COG0367	asparagine synthase
TD69_11195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_11200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD69_11235	COG0668	transmembrane transport
TD69_11240	COG4585	Histidine kinase
TD69_11240	COG2203	Gaf domain
TD69_11245	COG2197	response regulator
TD69_11255	COG1737	Transcriptional regulator
TD69_11260	COG1064	alcohol dehydrogenase
TD69_11290	COG1070	Carbohydrate kinase
TD69_11325	COG1125	glycine betaine transport
TD69_11325	COG0517	IMP dehydrogenase activity
TD69_11330	COG1174	glycine betaine transport
TD69_11365	COG1253	flavin adenine dinucleotide binding
TD69_11370	COG1012	belongs to the aldehyde dehydrogenase family
TD69_11375	COG5506	Protein of unknown function (DUF1694)
TD69_11390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD69_11395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
TD69_11400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TD69_11405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD69_11410	COG0456	acetyltransferase
TD69_11415	COG3829	transcription factor binding
TD69_11420	COG1509	lysine 2,3-aminomutase activity
TD69_11460	COG4326	sporulation control protein
TD69_11465	COG0671	phosphoesterase, PA-phosphatase related
TD69_11470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD69_11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD69_11505	COG1715	Restriction endonuclease
TD69_11505	COG1787	Restriction endonuclease
TD69_11595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD69_11635	COG4499	WXG100 protein secretion system (Wss), protein YukC
TD69_11635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD69_11640	COG2814	Major facilitator Superfamily
TD69_11645	COG4841	protein insertion into membrane
TD69_11650	COG0372	Belongs to the citrate synthase family
TD69_11655	COG2079	MmgE PrpD family protein
TD69_11660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TD69_11665	COG1960	acyl-CoA dehydrogenase activity
TD69_11670	COG2084	Dehydrogenase
TD69_11675	COG1012	belongs to the aldehyde dehydrogenase family
TD69_11680	COG1280	lysine exporter protein (LysE YggA)
TD69_11685	COG1024	Enoyl-CoA hydratase
TD69_11700	COG0420	3'-5' exonuclease activity
TD69_11705	COG0419	ATPase involved in DNA repair
TD69_11735	COG2223	nitrite transmembrane transporter activity
TD69_11740	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_11745	COG1169	isochorismate synthase
TD69_11750	COG1021	2,3-dihydroxybenzoate-AMP ligase
TD69_11755	COG1535	isochorismatase
TD69_11755	COG3433	isochorismatase activity
TD69_11760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD69_11765	COG3251	PFAM MbtH domain protein
TD69_11770	COG2814	Major facilitator Superfamily
TD69_11785	COG0776	regulation of translation
TD69_11795	COG2318	DinB family
TD69_11805	COG1115	amino acid carrier protein
TD69_11825	COG2329	Antibiotic biosynthesis monooxygenase
TD69_11830	COG1187	pseudouridine synthase activity
TD69_11835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TD69_11850	COG0596	Alpha beta hydrolase
TD69_11855	COG2814	Major facilitator Superfamily
TD69_11875	COG2226	methyltransferase
TD69_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_11955	COG1247	-acetyltransferase
TD69_11995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_12005	COG1278	Cold shock
TD69_12020	COG0010	Belongs to the arginase family
TD69_12025	COG0561	phosphatase activity
TD69_12070	COG0583	DNA-binding transcription factor activity
TD69_12075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TD69_12090	COG0583	DNA-binding transcription factor activity
TD69_12095	COG2258	MOSC domain
TD69_12110	COG1132	(ABC) transporter
TD69_12115	COG1132	(ABC) transporter
TD69_12135	COG1396	sequence-specific DNA binding
TD69_12165	COG1595	DNA-templated transcription, initiation
TD69_12220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TD69_12225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TD69_12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_12275	COG1309	transcriptional regulator
TD69_12290	COG1136	(ABC) transporter
TD69_12290	COG0577	efflux transmembrane transporter activity
TD69_12295	COG3615	Tellurite resistance protein tehB
TD69_12295	COG0500	methyltransferase
TD69_12305	COG2226	methyltransferase
TD69_12310	COG3961	Belongs to the TPP enzyme family
TD69_12315	COG1846	Transcriptional regulator
TD69_12355	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD69_12370	COG1595	DNA-templated transcription, initiation
TD69_12380	COG0768	penicillin binding
TD69_12390	COG2367	Beta-lactamase
TD69_12395	COG0671	phosphoesterase, PA-phosphatase related
TD69_12400	COG1609	Transcriptional regulator
TD69_12405	COG2814	Major facilitator Superfamily
TD69_12410	COG0673	inositol 2-dehydrogenase activity
TD69_12420	COG1012	belongs to the aldehyde dehydrogenase family
TD69_12440	COG3718	enzyme involved in inositol metabolism
TD69_12455	COG0737	Belongs to the 5'-nucleotidase family
TD69_12470	COG0457	Tetratricopeptide repeat
TD69_12475	COG1476	TRANSCRIPTIONal
TD69_12490	COG1876	peptidase activity
TD69_12510	COG1309	transcriptional regulator
TD69_12530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_12540	COG1252	NADH dehydrogenase
TD69_12545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_12560	COG1131	(ABC) transporter
TD69_12570	COG1309	transcriptional regulator
TD69_12585	COG1960	acyl-CoA dehydrogenase activity
TD69_12590	COG0439	Biotin carboxylase
TD69_12595	COG0511	ligase activity, forming carbon-carbon bonds
TD69_12600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TD69_12605	COG1024	Enoyl-CoA hydratase
TD69_12610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TD69_12615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD69_12625	COG1247	-acetyltransferase
TD69_12630	COG0572	uridine kinase
TD69_12640	COG2318	DinB family
TD69_12645	COG1686	Belongs to the peptidase S11 family
TD69_12670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TD69_12710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TD69_12710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TD69_12725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD69_12735	COG2814	Major facilitator Superfamily
TD69_12755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD69_12775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_12790	COG1063	alcohol dehydrogenase
TD69_12805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TD69_12810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TD69_12825	COG3773	Cell wall hydrolase
TD69_12835	COG0745	RESPONSE REGULATOR receiver
TD69_12865	COG1136	(ABC) transporter
TD69_12890	COG0460	homoserine dehydrogenase
TD69_12895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_12905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TD69_12980	COG2124	cytochrome p450
TD69_13015	COG0561	phosphatase activity
TD69_13025	COG5002	protein histidine kinase activity
TD69_13035	COG1819	glycosyl
TD69_13040	COG1794	racemase activity, acting on amino acids and derivatives
TD69_13050	COG1122	ATPase activity
TD69_13060	COG2205	protein histidine kinase activity
TD69_13075	COG0604	alcohol dehydrogenase
TD69_13090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD69_13125	COG0693	protein deglycase activity
TD69_13155	COG2814	Major facilitator Superfamily
TD69_13170	COG0584	glycerophosphoryl diester phosphodiesterase
TD69_13190	COG0697	spore germination
TD69_13225	COG2223	nitrite transmembrane transporter activity
TD69_13240	COG2816	NAD+ diphosphatase activity
TD69_13245	COG0592	DNA-directed DNA polymerase activity
TD69_13250	COG1051	belongs to the nudix hydrolase family
TD69_13285	COG3878	Protein conserved in bacteria
TD69_13315	COG4667	esterase of the alpha-beta hydrolase superfamily
TD69_13340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TD69_13355	COG0322	excinuclease ABC activity
TD69_13395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD69_13420	COG1011	Hydrolase
TD69_13440	COG0076	glutamate decarboxylase activity
TD69_13455	COG1523	belongs to the glycosyl hydrolase 13 family
TD69_13460	COG3227	Zinc metalloprotease (Elastase)
TD69_13480	COG0201	protein transport
TD69_13490	COG0697	spore germination
TD69_13495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_13525	COG4129	membrane
TD69_13530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_13545	COG2959	enzyme of heme biosynthesis
TD69_13550	COG3409	Peptidoglycan-binding domain 1 protein
TD69_13550	COG3773	Cell wall hydrolase
TD69_13565	COG3483	tryptophan 2,3-dioxygenase activity
TD69_13570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TD69_13575	COG3844	kynureninase activity
TD69_13580	COG1309	transcriptional regulator
TD69_13610	COG3284	Transcriptional regulator
TD69_13630	COG1349	DNA-binding transcription factor activity
TD69_13650	COG1959	2 iron, 2 sulfur cluster binding
TD69_13665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD69_13670	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD69_13675	COG0022	dehydrogenase e1 component
TD69_13680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD69_13690	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_13695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TD69_13695	COG0456	acetyltransferase
TD69_13730	COG4176	ABC-type proline glycine betaine transport system permease component
TD69_13735	COG4175	Glycine betaine
TD69_13735	COG0517	IMP dehydrogenase activity
TD69_13745	COG0740	serine-type endopeptidase activity
TD69_13760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TD69_13765	COG2153	protein acetylation
TD69_13770	COG3397	chitin binding
TD69_13785	COG2205	protein histidine kinase activity
TD69_13815	COG0658	competence protein
TD69_13815	COG2333	competence protein COMEC
TD69_13865	COG3973	AAA domain
TD69_13880	COG2105	PFAM AIG2 family protein
TD69_13885	COG0514	ATP-dependent DNA helicase (RecQ)
TD69_13915	COG4637	Psort location Cytoplasmic, score
TD69_13940	COG3397	chitin binding
TD69_13950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TD69_13955	COG1115	amino acid carrier protein
TD69_13960	COG1012	belongs to the aldehyde dehydrogenase family
TD69_13965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TD69_13975	COG3938	Belongs to the proline racemase family
TD69_13980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD69_14020	COG0586	Pfam SNARE associated Golgi protein
TD69_14035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
TD69_14040	COG0519	Catalyzes the synthesis of GMP from XMP
TD69_14045	COG4166	transmembrane transport
TD69_14055	COG4948	Mandelate Racemase Muconate Lactonizing
TD69_14095	COG2936	dipeptidyl-peptidase activity
TD69_14100	COG5002	protein histidine kinase activity
TD69_14105	COG0745	RESPONSE REGULATOR receiver
TD69_14145	COG1307	EDD domain protein, DegV family
TD69_14165	COG2814	Major facilitator Superfamily
TD69_14175	COG1664	Polymer-forming cytoskeletal
TD69_14180	COG0789	Transcriptional regulator
TD69_14185	COG4533	DNA binding
TD69_14190	COG2814	Major facilitator Superfamily
TD69_14190	COG0477	Major facilitator Superfamily
TD69_14210	COG2261	transglycosylase associated protein
TD69_14225	COG2226	methyltransferase
TD69_14260	COG0436	Aminotransferase
TD69_14265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TD69_14270	COG5146	pantothenate kinase activity
TD69_14295	COG1131	(ABC) transporter
TD69_14345	COG0628	permease
TD69_14360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD69_14365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD69_14370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD69_14375	COG1116	anion transmembrane transporter activity
TD69_14415	COG2746	aminoglycoside 3-N-acetyltransferase activity
TD69_14440	COG0697	spore germination
TD69_14445	COG2318	DinB family
TD69_14465	COG4912	Dna alkylation repair
TD69_14475	COG0726	polysaccharide deacetylase
TD69_14485	COG0861	Integral membrane protein TerC family
TD69_14490	COG1368	sulfuric ester hydrolase activity
TD69_14495	COG0488	(ABC) transporter
TD69_14505	COG1033	growth of symbiont in host cell
TD69_14505	COG2409	Drug exporters of the RND superfamily
TD69_14510	COG2409	Drug exporters of the RND superfamily
TD69_14510	COG1033	growth of symbiont in host cell
TD69_14515	COG1033	growth of symbiont in host cell
TD69_14515	COG2409	Drug exporters of the RND superfamily
TD69_14520	COG1309	transcriptional regulator
TD69_14535	COG0287	Prephenate dehydrogenase
TD69_14540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TD69_14545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TD69_14550	COG1605	Chorismate mutase
TD69_14550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TD69_14585	COG3584	3D domain protein
TD69_14585	COG1388	LysM domain
TD69_14595	COG1595	DNA-templated transcription, initiation
TD69_14620	COG1879	ABC-type sugar transport system periplasmic component
TD69_14630	COG1172	Belongs to the binding-protein-dependent transport system permease family
TD69_14640	COG2390	Transcriptional regulator
TD69_14675	COG2329	Antibiotic biosynthesis monooxygenase
TD69_14695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_14705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TD69_14710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD69_14715	COG4187	Peptidase family M20/M25/M40
TD69_14720	COG1414	Transcriptional regulator
TD69_14725	COG0833	amino acid
TD69_14730	COG1690	Belongs to the RtcB family
TD69_14735	COG3239	Fatty acid desaturase
TD69_14740	COG1785	Belongs to the alkaline phosphatase family
TD69_14750	COG3655	Transcriptional regulator
TD69_14765	COG4377	Putative membrane peptidase family (DUF2324)
TD69_14775	COG3279	Response regulator of the LytR AlgR family
TD69_14785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_14790	COG0346	lactoylglutathione lyase activity
TD69_14810	COG0714	Associated with various cellular activities
TD69_14835	COG0463	Glycosyl transferase, family 2
TD69_14860	COG0463	Glycosyl transferase, family 2
TD69_14870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD69_14875	COG0753	catalase activity
TD69_14885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TD69_14910	COG0714	Associated with various cellular activities
TD69_14920	COG0778	Nitroreductase
TD69_14925	COG1846	Transcriptional regulator
TD69_14960	COG1725	Transcriptional regulator
TD69_14970	COG0577	efflux transmembrane transporter activity
TD69_14970	COG1136	(ABC) transporter
TD69_14995	COG2207	Transcriptional regulator
TD69_15000	COG0456	acetyltransferase
TD69_15020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_15040	COG0642	Histidine kinase
TD69_15045	COG0745	RESPONSE REGULATOR receiver
TD69_15050	COG0596	Alpha beta hydrolase
TD69_15080	COG0730	response to heat
TD69_15090	COG0833	amino acid
TD69_15100	COG4335	DNA alkylation repair
TD69_15150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TD69_15190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TD69_15195	COG1414	Transcriptional regulator
TD69_15210	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD69_15215	COG0640	Transcriptional regulator
TD69_15225	COG1960	acyl-CoA dehydrogenase activity
TD69_15260	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
TD69_15275	COG3848	Pyruvate phosphate dikinase
TD69_15275	COG0574	Belongs to the PEP-utilizing enzyme family
TD69_15280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_15295	COG5577	PFAM Coat F domain
TD69_15300	COG3403	YqcI/YcgG family
TD69_15305	COG1280	lysine exporter protein (LysE YggA)
TD69_15340	COG1063	alcohol dehydrogenase
TD69_15355	COG1027	Aspartate ammonia-lyase
TD69_15360	COG0252	asparaginase activity
TD69_15365	COG1396	sequence-specific DNA binding
TD69_15375	COG0322	excinuclease ABC activity
TD69_15380	COG0531	amino acid
TD69_15385	COG1114	Component of the transport system for branched-chain amino acids
TD69_15390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD69_15400	COG0281	malic enzyme
TD69_15425	COG0697	spore germination
TD69_15430	COG0784	Response regulator, receiver
TD69_15440	COG2066	Belongs to the glutaminase family
TD69_15470	COG0737	Belongs to the 5'-nucleotidase family
TD69_15475	COG0753	catalase activity
TD69_15480	COG2267	carboxylic ester hydrolase activity
TD69_15485	COG1335	isochorismatase
TD69_15510	COG0583	DNA-binding transcription factor activity
TD69_15555	COG0415	Belongs to the DNA photolyase family
TD69_15560	COG0288	reversible hydration of carbon dioxide
TD69_15570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD69_15575	COG5609	conserved protein (DUF2294)
TD69_15585	COG1575	Belongs to the MenA family. Type 1 subfamily
TD69_15590	COG2267	carboxylic ester hydrolase activity
TD69_15595	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD69_15600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD69_15605	COG1121	(ABC) transporter
TD69_15635	COG0798	PFAM Bile acid sodium symporter
TD69_15640	COG0346	lactoylglutathione lyase activity
TD69_15645	COG0640	Transcriptional regulator
TD69_15660	COG0443	Heat shock 70 kDa protein
TD69_15675	COG1522	sequence-specific DNA binding
TD69_15690	COG0346	lactoylglutathione lyase activity
TD69_15715	COG2169	Transcriptional regulator
TD69_15760	COG2814	Major facilitator Superfamily
TD69_15785	COG0745	RESPONSE REGULATOR receiver
TD69_15790	COG5002	protein histidine kinase activity
TD69_15790	COG3850	Histidine kinase
TD69_15820	COG2515	1-aminocyclopropane-1-carboxylate deaminase
TD69_15845	COG1476	TRANSCRIPTIONal
TD69_15860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_15865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD69_15875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_15880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
TD69_15895	COG1136	(ABC) transporter
TD69_15900	COG0577	efflux transmembrane transporter activity
TD69_15920	COG3850	Histidine kinase
TD69_15920	COG5002	protein histidine kinase activity
TD69_15930	COG2364	Membrane
TD69_15935	COG1846	Transcriptional regulator
TD69_15945	COG2808	Putative FMN-binding domain
TD69_15950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_15955	COG2271	Major facilitator Superfamily
TD69_15960	COG1556	Lactate utilization protein
TD69_15965	COG1139	Iron-sulfur cluster binding protein
TD69_15975	COG0583	DNA-binding transcription factor activity
TD69_15985	COG1619	proteins homologs of microcin C7 resistance protein MccF
TD69_16015	COG0738	Major facilitator superfamily
TD69_16020	COG0673	inositol 2-dehydrogenase activity
TD69_16025	COG0561	phosphatase activity
TD69_16035	COG1609	Transcriptional regulator
TD69_16040	COG0457	Tetratricopeptide repeat
TD69_16060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD69_16090	COG0534	Mate efflux family protein
TD69_16105	COG2814	Major facilitator Superfamily
TD69_16110	COG1309	transcriptional regulator
TD69_16125	COG0814	amino acid
TD69_16130	COG1760	l-serine dehydratase
TD69_16135	COG1760	l-serine dehydratase
TD69_16145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TD69_16150	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TD69_16160	COG1335	isochorismatase
TD69_16165	COG1522	sequence-specific DNA binding
TD69_16170	COG0531	amino acid
TD69_16185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TD69_16205	COG1595	DNA-templated transcription, initiation
TD69_16220	COG0662	Cupin 2, conserved barrel domain protein
TD69_16230	COG2207	Transcriptional regulator
TD69_16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_16285	COG0477	Major facilitator Superfamily
TD69_16295	COG1846	Transcriptional regulator
TD69_16300	COG2814	Major facilitator Superfamily
TD69_16315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD69_16320	COG1131	(ABC) transporter
TD69_16340	COG2076	Multidrug Resistance protein
TD69_16345	COG1309	transcriptional regulator
TD69_16360	COG2031	fatty acid transporter
TD69_16370	COG2249	NAD(P)H dehydrogenase (quinone) activity
TD69_16400	COG1122	ATPase activity
TD69_16405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD69_16420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TD69_16425	COG1288	antiporter activity
TD69_16430	COG2356	endonuclease I
TD69_16445	COG3620	sequence-specific DNA binding
TD69_16450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TD69_16455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TD69_16460	COG0124	histidyl-tRNA synthetase
TD69_16475	COG1733	regulation of RNA biosynthetic process
TD69_16480	COG0778	Nitroreductase
TD69_16500	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_16510	COG1131	(ABC) transporter
TD69_16535	COG1011	Hydrolase
TD69_16570	COG0346	lactoylglutathione lyase activity
TD69_16575	COG1940	carbohydrate kinase activity
TD69_16580	COG0738	Major facilitator superfamily
TD69_16585	COG0110	maltose O-acetyltransferase activity
TD69_16600	COG1136	(ABC) transporter
TD69_16605	COG0180	Tryptophanyl-tRNA synthetase
TD69_16610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TD69_16615	COG0628	permease
TD69_16635	COG2226	methyltransferase
TD69_16645	COG0477	Major facilitator Superfamily
TD69_16675	COG1253	flavin adenine dinucleotide binding
TD69_16680	COG0789	Transcriptional regulator
TD69_16685	COG0697	spore germination
TD69_16690	COG1357	PFAM Pentapeptide repeats (8 copies)
TD69_16695	COG3813	Protein conserved in bacteria
TD69_16700	COG2706	6-phosphogluconolactonase activity
TD69_16705	COG1070	Carbohydrate kinase
TD69_16715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TD69_16720	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TD69_16730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TD69_16735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TD69_16740	COG0604	alcohol dehydrogenase
TD69_16745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD69_16765	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_16790	COG0656	L-ascorbic acid biosynthetic process
TD69_16795	COG2814	Major facilitator Superfamily
TD69_16810	COG0346	lactoylglutathione lyase activity
TD69_16815	COG0814	amino acid
TD69_16840	COG1393	Belongs to the ArsC family
TD69_16850	COG1733	regulation of RNA biosynthetic process
TD69_16855	COG2188	Transcriptional regulator
TD69_16865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TD69_16870	COG1733	regulation of RNA biosynthetic process
TD69_16875	COG1733	regulation of RNA biosynthetic process
TD69_16890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_16910	COG0384	phenazine biosynthesis protein PhzF
TD69_16920	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_16930	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_16940	COG1733	regulation of RNA biosynthetic process
TD69_16975	COG1191	sigma factor activity
TD69_16990	COG1309	transcriptional regulator
TD69_17010	COG3152	Membrane
TD69_17035	COG1151	hydroxylamine reductase activity
TD69_17045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_17050	COG3409	Peptidoglycan-binding domain 1 protein
TD69_17050	COG3757	hydrolase, family 25
TD69_17085	COG2072	flavoprotein involved in K transport
TD69_17125	COG1113	amino acid transport
TD69_17130	COG2814	Major facilitator Superfamily
TD69_17165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD69_17170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TD69_17190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_17200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_17210	COG3739	integral membrane protein
TD69_17215	COG0384	phenazine biosynthesis protein PhzF
TD69_17245	COG0583	DNA-binding transcription factor activity
TD69_17265	COG1193	negative regulation of DNA recombination
TD69_17280	COG2162	N-hydroxyarylamine O-acetyltransferase activity
TD69_17285	COG1164	Oligoendopeptidase f
TD69_17290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD69_17320	COG0584	glycerophosphoryl diester phosphodiesterase
TD69_17345	COG0640	Transcriptional regulator
TD69_17350	COG0604	alcohol dehydrogenase
TD69_17370	COG2808	Putative FMN-binding domain
TD69_17375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TD69_17385	COG0385	Bile acid
TD69_17390	COG0277	FAD linked oxidase domain protein
TD69_17425	COG1216	Glycosyl transferase, family 2
TD69_17430	COG1024	Enoyl-CoA hydratase
TD69_17440	COG1285	pathogenesis
TD69_17450	COG2514	catechol 2,3-dioxygenase activity
TD69_17455	COG2720	vancomycin resistance protein
TD69_17485	COG1278	Cold shock
TD69_17495	COG0716	FMN binding
TD69_17525	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_17535	COG0165	Argininosuccinate lyase
TD69_17550	COG4145	pantothenate transmembrane transporter activity
TD69_17560	COG1012	belongs to the aldehyde dehydrogenase family
TD69_17565	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_17575	COG1657	PFAM Prenyltransferase squalene oxidase
TD69_17580	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TD69_17585	COG2962	Rard protein
TD69_17590	COG3326	Membrane
TD69_17605	COG0489	protein tyrosine kinase activity
TD69_17615	COG0314	molybdopterin synthase activity
TD69_17620	COG0303	'Molybdopterin
TD69_17625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD69_17630	COG2116	formate transmembrane transporter activity
TD69_17640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TD69_17645	COG5609	conserved protein (DUF2294)
TD69_17650	COG2427	Protein of unknown function (DUF1641)
TD69_17655	COG3383	formate dehydrogenase (NAD+) activity
TD69_17665	COG0697	spore germination
TD69_17705	COG2226	methyltransferase
TD69_17710	COG4166	transmembrane transport
TD69_17715	COG4166	transmembrane transport
TD69_17730	COG1316	TRANSCRIPTIONal
TD69_17740	COG1595	DNA-templated transcription, initiation
TD69_17765	COG1131	(ABC) transporter
TD69_17775	COG0673	inositol 2-dehydrogenase activity
TD69_17780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD69_17785	COG0187	DNA topoisomerase II activity
TD69_17795	COG1832	CoA-binding protein
TD69_17800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD69_17805	COG0745	RESPONSE REGULATOR receiver
TD69_17820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TD69_17825	COG4841	protein insertion into membrane
TD69_17830	COG0824	Thioesterase
TD69_17860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD69_17870	COG2274	protein secretion by the type I secretion system
TD69_17875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TD69_17885	COG0726	polysaccharide deacetylase
TD69_17905	COG2211	Major facilitator Superfamily
TD69_17915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TD69_17930	COG0183	Belongs to the thiolase family
TD69_17935	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_17940	COG1268	BioY protein
TD69_17945	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_17990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_18000	COG5002	protein histidine kinase activity
TD69_18005	COG0400	carboxylic ester hydrolase activity
TD69_18010	COG0346	lactoylglutathione lyase activity
TD69_18015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD69_18020	COG0069	glutamate synthase activity
TD69_18025	COG1902	pentaerythritol trinitrate reductase activity
TD69_18030	COG1329	Transcriptional regulator
TD69_18035	COG0010	Belongs to the arginase family
TD69_18060	COG2226	methyltransferase
TD69_18115	COG4846	Membrane protein involved in cytochrome C biogenesis
TD69_18120	COG0785	Cytochrome C biogenesis protein
TD69_18130	COG0583	DNA-binding transcription factor activity
TD69_18135	COG1380	Effector of murein hydrolase LrgA
TD69_18140	COG1346	cytolysis
TD69_18155	COG0730	response to heat
TD69_18165	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD69_18165	COG3409	Peptidoglycan-binding domain 1 protein
TD69_18180	COG1132	(ABC) transporter
TD69_18185	COG1132	(ABC) transporter
TD69_18220	COG3639	organic phosphonate transmembrane transporter activity
TD69_18225	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TD69_18240	COG0737	Belongs to the 5'-nucleotidase family
TD69_18250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TD69_18270	COG1695	Transcriptional regulator
TD69_18305	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD69_18305	COG3409	Peptidoglycan-binding domain 1 protein
TD69_18305	COG1388	LysM domain
TD69_18310	COG4824	toxin secretion phage lysis holin
TD69_18470	COG1595	DNA-templated transcription, initiation
TD69_18515	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TD69_18595	COG1396	sequence-specific DNA binding
TD69_18620	COG0174	glutamine synthetase
TD69_18625	COG0789	Transcriptional regulator
TD69_18630	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
TD69_18640	COG2860	membrane
TD69_18645	COG0464	growth
TD69_18675	COG3584	3D domain protein
TD69_18675	COG1388	LysM domain
TD69_18680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD69_18680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD69_18680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD69_18685	COG1105	Belongs to the carbohydrate kinase PfkB family
TD69_18690	COG1349	DNA-binding transcription factor activity
TD69_18700	COG2322	membrane
TD69_18715	COG1113	amino acid transport
TD69_18725	COG1408	metallophosphoesterase
TD69_18730	COG2116	formate transmembrane transporter activity
TD69_18740	COG2217	Heavy metal translocating P-type atpase
TD69_18745	COG2608	mercury ion transmembrane transporter activity
TD69_18750	COG1937	Protein conserved in bacteria
TD69_18760	COG2819	hydrolase of the alpha beta superfamily
TD69_18765	COG1120	ATPase activity
TD69_18770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_18775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_18780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_18790	COG0708	Exodeoxyribonuclease III
TD69_18795	COG2169	Transcriptional regulator
TD69_18800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD69_18805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TD69_18815	COG2364	Membrane
TD69_18830	COG2267	carboxylic ester hydrolase activity
TD69_18835	COG0346	lactoylglutathione lyase activity
TD69_18840	COG3300	MHYT domain
TD69_18840	COG5001	Diguanylate cyclase
TD69_18860	COG1346	cytolysis
TD69_18865	COG1380	Effector of murein hydrolase LrgA
TD69_18870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD69_18875	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD69_18875	COG0596	Alpha beta hydrolase
TD69_18880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD69_18895	COG1404	Belongs to the peptidase S8 family
TD69_18900	COG3773	Cell wall hydrolase
TD69_18905	COG0562	UDP-galactopyranose mutase
TD69_18910	COG1368	sulfuric ester hydrolase activity
TD69_18915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD69_18925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
TD69_18970	COG4550	Control of competence regulator ComK, YlbF/YmcA
TD69_18975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TD69_18980	COG1013	pyruvate-flavodoxin oxidoreductase activity
TD69_18985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TD69_18985	COG0674	pyruvate-flavodoxin oxidoreductase activity
TD69_18995	COG2359	stage V sporulation protein S
TD69_19000	COG1692	metallophosphoesterase
TD69_19025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TD69_19030	COG1426	Protein conserved in bacteria
TD69_19045	COG0300	oxidoreductase activity
TD69_19050	COG0612	Peptidase, M16
TD69_19055	COG0612	Peptidase, M16
TD69_19085	COG2188	Transcriptional regulator
TD69_19090	COG1674	ftsk spoiiie
TD69_19100	COG0740	serine-type endopeptidase activity
TD69_19105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD69_19120	COG0527	aspartate kinase activity
TD69_19125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TD69_19130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD69_19135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD69_19140	COG1873	PFAM PRC-barrel domain
TD69_19145	COG0612	Peptidase, M16
TD69_19150	COG0726	polysaccharide deacetylase
TD69_19165	COG0196	riboflavin kinase activity
TD69_19170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TD69_19180	COG1550	Protein conserved in bacteria
TD69_19190	COG1358	cellular component organization or biogenesis
TD69_19195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
TD69_19200	COG0195	Participates in both transcription termination and antitermination
TD69_19220	COG0750	zinc metalloprotease
TD69_19225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TD69_19230	COG4589	Belongs to the CDS family
TD69_19235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TD69_19245	COG0528	UMP kinase activity
TD69_19275	COG4974	Belongs to the 'phage' integrase family
TD69_19285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD69_19295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TD69_19335	COG1837	Belongs to the UPF0109 family
TD69_19345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TD69_19355	COG0552	protein localization to endoplasmic reticulum
TD69_19360	COG1196	nuclear chromosome segregation
TD69_19375	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_19380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD69_19395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TD69_19400	COG1461	Dihydroxyacetone kinase
TD69_19405	COG1302	Protein conserved in bacteria
TD69_19420	COG1564	THIamine pyrophosphokinase
TD69_19425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TD69_19430	COG1162	GTPase activity
TD69_19435	COG2815	serine threonine protein kinase
TD69_19435	COG0515	serine threonine protein kinase
TD69_19440	COG0631	protein serine/threonine phosphatase activity
TD69_19450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TD69_19450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TD69_19460	COG0242	peptide deformylase activity
TD69_19465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TD69_19470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD69_19480	COG0194	GDP metabolic process
TD69_19490	COG1561	YicC-like family, N-terminal region
TD69_19495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TD69_19505	COG0006	proline dipeptidase activity
TD69_19520	COG3069	C4-dicarboxylate transmembrane transporter activity
TD69_19560	COG0505	Belongs to the CarA family
TD69_19585	COG0564	pseudouridine synthase activity
TD69_19600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TD69_19605	COG3599	regulation of cell shape
TD69_19610	COG2302	S4 RNA-binding domain
TD69_19615	COG0762	integral membrane protein
TD69_19625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TD69_19635	COG1873	PFAM PRC-barrel domain
TD69_19640	COG1191	sigma factor activity
TD69_19645	COG1191	sigma factor activity
TD69_19655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TD69_19660	COG0849	cell division
TD69_19665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TD69_19670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TD69_19675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD69_19680	COG0772	Belongs to the SEDS family
TD69_19695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TD69_19700	COG0768	penicillin binding
TD69_19710	COG4839	cell division protein FtsL
TD69_19725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD69_19745	COG1399	metal-binding, possibly nucleic acid-binding protein
TD69_19795	COG4824	toxin secretion phage lysis holin
TD69_19890	COG1802	Transcriptional regulator
TD69_19890	COG4626	Terminase
TD69_19915	COG0582	viral genome integration into host DNA
TD69_19995	COG1191	sigma factor activity
TD69_20020	COG1484	DNA-dependent DNA replication
TD69_20050	COG1396	sequence-specific DNA binding
TD69_20060	COG1396	sequence-specific DNA binding
TD69_20075	COG0582	viral genome integration into host DNA
TD69_20085	COG3480	Lon protease (S16) C-terminal proteolytic domain
TD69_20090	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD69_20095	COG3314	Sporulation integral membrane protein YlbJ
TD69_20105	COG0742	ribosomal rna small subunit methyltransferase
TD69_20120	COG3679	Belongs to the UPF0342 family
TD69_20125	COG0406	alpha-ribazole phosphatase activity
TD69_20140	COG2340	Cysteine-rich secretory protein family
TD69_20155	COG3336	cytochrome c oxidase
TD69_20190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TD69_20195	COG0772	Belongs to the SEDS family
TD69_20200	COG4838	Belongs to the UPF0358 family
TD69_20205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TD69_20210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TD69_20220	COG4896	Protein conserved in bacteria
TD69_20245	COG0483	inositol monophosphate 1-phosphatase activity
TD69_20265	COG1982	Orn Lys Arg decarboxylase major
TD69_20310	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD69_20315	COG0022	dehydrogenase e1 component
TD69_20320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD69_20330	COG0242	peptide deformylase activity
TD69_20335	COG0561	phosphatase activity
TD69_20345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD69_20350	COG0569	domain protein
TD69_20370	COG0583	DNA-binding transcription factor activity
TD69_20375	COG0517	IMP dehydrogenase activity
TD69_20385	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
TD69_20395	COG4703	Protein of unknown function (DUF1797)
TD69_20410	COG2200	EAL domain
TD69_20415	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_20420	COG1408	metallophosphoesterase
TD69_20430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TD69_20470	COG2814	Major facilitator Superfamily
TD69_20495	COG3209	COG3209 Rhs family protein
TD69_20505	COG2205	protein histidine kinase activity
TD69_20515	COG0436	Aminotransferase
TD69_20520	COG1609	Transcriptional regulator
TD69_20525	COG3833	ABC-type maltose transport systems, permease component
TD69_20530	COG1175	transmembrane transport
TD69_20535	COG2182	Extracellular solute-binding protein
TD69_20545	COG0366	Alpha amylase catalytic
TD69_20550	COG3842	ATPase activity
TD69_20590	COG0183	Belongs to the thiolase family
TD69_20630	COG1695	Transcriptional regulator
TD69_20635	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_20655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TD69_20660	COG0436	Aminotransferase
TD69_20680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
TD69_20700	COG3706	GGDEF domain
TD69_20705	COG0778	Nitroreductase
TD69_20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD69_20730	COG1263	PTS System
TD69_20730	COG2190	(PTS) system
TD69_20735	COG3711	transcriptional antiterminator
TD69_20755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TD69_20785	COG1547	Domain of unknown function (DUF309)
TD69_20790	COG0456	acetyltransferase
TD69_20800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD69_20805	COG4086	secreted protein
TD69_20810	COG0561	phosphatase activity
TD69_20815	COG0697	spore germination
TD69_20830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_20855	COG0733	neurotransmitter:sodium symporter activity
TD69_20875	COG1686	Belongs to the peptidase S11 family
TD69_20880	COG1725	Transcriptional regulator
TD69_20885	COG1131	(ABC) transporter
TD69_20905	COG1846	Transcriptional regulator
TD69_20920	COG0598	Magnesium transport protein CorA
TD69_20945	COG4974	Belongs to the 'phage' integrase family
TD69_20955	COG0735	belongs to the Fur family
TD69_20960	COG1300	Membrane
TD69_20980	COG0667	Aldo Keto reductase
TD69_20985	COG0656	L-ascorbic acid biosynthetic process
TD69_20990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TD69_20990	COG0456	acetyltransferase
TD69_21000	COG1525	nuclease
TD69_21000	COG0737	Belongs to the 5'-nucleotidase family
TD69_21000	COG4085	toxin activity
TD69_21010	COG0596	Alpha beta hydrolase
TD69_21015	COG2056	Na+-H+ antiporter family
TD69_21020	COG1609	Transcriptional regulator
TD69_21025	COG0456	acetyltransferase
TD69_21030	COG1073	alpha beta
TD69_21045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD69_21045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD69_21050	COG0307	riboflavin synthase, alpha
TD69_21070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TD69_21075	COG4106	trans-aconitate 2-methyltransferase activity
TD69_21080	COG1073	alpha beta
TD69_21080	COG2226	methyltransferase
TD69_21085	COG0156	8-amino-7-oxononanoate synthase activity
TD69_21095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD69_21110	COG0737	Belongs to the 5'-nucleotidase family
TD69_21120	COG1522	sequence-specific DNA binding
TD69_21140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD69_21150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TD69_21165	COG0300	oxidoreductase activity
TD69_21170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_21180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD69_21185	COG1760	l-serine dehydratase
TD69_21190	COG1760	l-serine dehydratase
TD69_21210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD69_21220	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD69_21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_21240	COG1376	ErfK ybiS ycfS ynhG family protein
TD69_21245	COG4129	membrane
TD69_21250	COG1126	abc transporter atp-binding protein
TD69_21255	COG0765	amino acid transport
TD69_21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD69_21285	COG0772	Belongs to the SEDS family
TD69_21295	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD69_21300	COG0022	dehydrogenase e1 component
TD69_21305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD69_21310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD69_21320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD69_21325	COG0280	phosphate acetyltransferase
TD69_21335	COG3829	transcription factor binding
TD69_21335	COG3290	protein histidine kinase activity
TD69_21345	COG0584	glycerophosphoryl diester phosphodiesterase
TD69_21350	COG3093	addiction module antidote protein HigA
TD69_21360	COG0745	RESPONSE REGULATOR receiver
TD69_21365	COG0750	zinc metalloprotease
TD69_21370	COG0497	DNA recombination
TD69_21380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
TD69_21390	COG0142	geranyltranstransferase activity
TD69_21415	COG1302	Protein conserved in bacteria
TD69_21420	COG0439	Biotin carboxylase
TD69_21425	COG0511	ligase activity, forming carbon-carbon bonds
TD69_21470	COG3854	ATPases associated with a variety of cellular activities
TD69_21495	COG0006	proline dipeptidase activity
TD69_21510	COG3872	metal-dependent enzyme
TD69_21520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TD69_21540	COG0095	Lipoate-protein ligase
TD69_21545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_21550	COG1609	Transcriptional regulator
TD69_21560	COG2076	Multidrug Resistance protein
TD69_21565	COG2076	Multidrug Resistance protein
TD69_21605	COG1131	(ABC) transporter
TD69_21610	COG1725	Transcriptional regulator
TD69_21640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD69_21695	COG4970	Tfp pilus assembly protein FimT
TD69_21705	COG1459	type II secretion system
TD69_21710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TD69_21760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD69_21765	COG1410	methionine synthase
TD69_21765	COG0646	methionine synthase
TD69_21770	COG0646	methionine synthase
TD69_21770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TD69_21780	COG0626	cystathionine gamma-synthase activity
TD69_21785	COG0626	cystathionine gamma-synthase activity
TD69_21810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_21820	COG1940	carbohydrate kinase activity
TD69_21825	COG4483	Protein conserved in bacteria
TD69_21830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TD69_21840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TD69_21845	COG0704	Plays a role in the regulation of phosphate uptake
TD69_21850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD69_21855	COG0581	inorganic phosphate transmembrane transporter activity
TD69_21860	COG0573	inorganic phosphate transmembrane transporter activity
TD69_21865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TD69_21875	COG0477	Major facilitator Superfamily
TD69_21880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD69_21905	COG0735	belongs to the Fur family
TD69_21910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD69_21915	COG1121	(ABC) transporter
TD69_21920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_21950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TD69_21955	COG2384	SAM-dependent methyltransferase
TD69_21960	COG2010	Cytochrome c
TD69_21965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TD69_21970	COG0358	DNA primase activity
TD69_21990	COG0517	IMP dehydrogenase activity
TD69_22005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TD69_22010	COG0295	cytidine deaminase activity
TD69_22015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TD69_22025	COG1480	7TM receptor with intracellular HD hydrolase
TD69_22030	COG1702	phosphate starvation-inducible protein PhoH
TD69_22050	COG1610	YqeY-like protein
TD69_22060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TD69_22065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TD69_22085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TD69_22095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD69_22100	COG1733	regulation of RNA biosynthetic process
TD69_22125	COG1466	dna polymerase III delta subunit
TD69_22135	COG2333	competence protein COMEC
TD69_22135	COG0658	competence protein
TD69_22140	COG2131	deaminase
TD69_22145	COG1596	polysaccharide export
TD69_22145	COG1555	photosystem II stabilization
TD69_22150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD69_22155	COG2226	methyltransferase
TD69_22160	COG0799	negative regulation of ribosome biogenesis
TD69_22165	COG1713	HD superfamily hydrolase involved in NAD metabolism
TD69_22175	COG1534	Rna-binding protein
TD69_22185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TD69_22190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TD69_22205	COG1191	sigma factor activity
TD69_22215	COG1595	DNA-templated transcription, initiation
TD69_22225	COG0778	Nitroreductase
TD69_22230	COG2357	RelA SpoT domain protein
TD69_22240	COG1785	Belongs to the alkaline phosphatase family
TD69_22250	COG2267	carboxylic ester hydrolase activity
TD69_22285	COG1404	Belongs to the peptidase S8 family
TD69_22290	COG3186	Phenylalanine-4-hydroxylase
TD69_22300	COG2514	catechol 2,3-dioxygenase activity
TD69_22305	COG2514	catechol 2,3-dioxygenase activity
TD69_22310	COG2259	Doxx family
TD69_22350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_22360	COG1454	alcohol dehydrogenase
TD69_22360	COG1012	belongs to the aldehyde dehydrogenase family
TD69_22365	COG0626	cystathionine gamma-synthase activity
TD69_22370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD69_22395	COG0768	penicillin binding
TD69_22425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TD69_22445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TD69_22455	COG0628	permease
TD69_22475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TD69_22485	COG0482	sulfurtransferase activity
TD69_22490	COG1104	cysteine desulfurase activity
TD69_22495	COG1959	2 iron, 2 sulfur cluster binding
TD69_22500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TD69_22510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TD69_22520	COG0124	histidyl-tRNA synthetase
TD69_22535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TD69_22545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TD69_22545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TD69_22550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD69_22555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD69_22555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD69_22565	COG2244	polysaccharide biosynthetic process
TD69_22570	COG2323	membrane
TD69_22580	COG1862	Preprotein translocase
TD69_22610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TD69_22620	COG0697	spore germination
TD69_22625	COG0697	spore germination
TD69_22630	COG0640	Transcriptional regulator
TD69_22655	COG0157	Belongs to the NadC ModD family
TD69_22660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TD69_22665	COG1104	cysteine desulfurase activity
TD69_22670	COG1827	regulation of RNA biosynthetic process
TD69_22675	COG2258	MOSC domain
TD69_22680	COG0077	Prephenate dehydratase
TD69_22685	COG0577	efflux transmembrane transporter activity
TD69_22690	COG0577	efflux transmembrane transporter activity
TD69_22695	COG1136	(ABC) transporter
TD69_22700	COG5002	protein histidine kinase activity
TD69_22710	COG0745	RESPONSE REGULATOR receiver
TD69_22715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TD69_22720	COG3290	protein histidine kinase activity
TD69_22730	COG2868	ribosomal protein
TD69_22740	COG1530	ribonuclease E activity
TD69_22745	COG1994	Peptidase M50
TD69_22750	COG0739	heme binding
TD69_22755	COG2894	cell division
TD69_22770	COG1792	Involved in formation and maintenance of cell shape
TD69_22775	COG1077	Cell shape determining protein MreB Mrl
TD69_22795	COG0285	dihydrofolate synthase activity
TD69_22800	COG0525	valine-tRNA ligase activity
TD69_22810	COG1388	LysM domain
TD69_22820	COG0113	porphobilinogen synthase activity
TD69_22825	COG1587	Uroporphyrinogen-III synthase
TD69_22835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD69_22845	COG1846	Transcriptional regulator
TD69_22850	COG1764	response to oxidative stress
TD69_22865	COG0470	DNA polymerase III
TD69_22865	COG1067	ATP-dependent peptidase activity
TD69_22915	COG0622	Phosphoesterase
TD69_22920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TD69_22930	COG5401	PFAM Sporulation and spore germination
TD69_22950	COG1309	transcriptional regulator
TD69_22965	COG2197	response regulator
TD69_22970	COG2233	PERMEase
TD69_22980	COG0402	S-adenosylhomocysteine deaminase activity
TD69_22985	COG0402	S-adenosylhomocysteine deaminase activity
TD69_23005	COG0444	Belongs to the ABC transporter superfamily
TD69_23010	COG4608	Belongs to the ABC transporter superfamily
TD69_23015	COG3275	phosphorelay sensor kinase activity
TD69_23020	COG3279	Response regulator of the LytR AlgR family
TD69_23035	COG1983	PspC domain protein
TD69_23040	COG1396	sequence-specific DNA binding
TD69_23045	COG0697	spore germination
TD69_23055	COG1959	2 iron, 2 sulfur cluster binding
TD69_23060	COG1668	transmembrane transport
TD69_23065	COG4152	abc transporter atp-binding protein
TD69_23070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
TD69_23080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD69_23085	COG1876	peptidase activity
TD69_23090	COG0824	Thioesterase
TD69_23095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TD69_23100	COG1053	succinate dehydrogenase
TD69_23105	COG2009	succinate dehydrogenase
TD69_23110	COG1719	4-vinyl reductase, 4VR
TD69_23120	COG3118	belongs to the thioredoxin family
TD69_23125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TD69_23130	COG2086	electron transfer activity
TD69_23135	COG1024	Enoyl-CoA hydratase
TD69_23140	COG1309	transcriptional regulator
TD69_23145	COG0318	PFAM AMP-dependent synthetase and ligase
TD69_23165	COG2318	DinB family
TD69_23195	COG1131	(ABC) transporter
TD69_23200	COG2205	protein histidine kinase activity
TD69_23205	COG0745	RESPONSE REGULATOR receiver
TD69_23215	COG4895	conserved protein (DUF2196)
TD69_23220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TD69_23235	COG4509	Sortase family
TD69_23240	COG1120	ATPase activity
TD69_23255	COG5386	Cell surface protein
TD69_23265	COG5386	Cell surface protein
TD69_23270	COG1114	Component of the transport system for branched-chain amino acids
TD69_23275	COG1187	pseudouridine synthase activity
TD69_23290	COG1796	DNA polymerase
TD69_23290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD69_23295	COG1286	toxin biosynthetic process
TD69_23325	COG0017	Asparaginyl-tRNA synthetase
TD69_23330	COG0072	phenylalanine-tRNA ligase activity
TD69_23330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_23340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD69_23350	COG1418	mRNA catabolic process
TD69_23375	COG2814	Major facilitator Superfamily
TD69_23380	COG1566	PFAM secretion protein HlyD family protein
TD69_23385	COG1309	transcriptional regulator
TD69_23390	COG1363	Peptidase, m42
TD69_23410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TD69_23415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TD69_23425	COG1484	DNA-dependent DNA replication
TD69_23430	COG3611	Membrane attachment protein
TD69_23440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TD69_23445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD69_23450	COG0237	dephospho-CoA kinase activity
TD69_23455	COG1971	Probably functions as a manganese efflux pump
TD69_23460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TD69_23465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD69_23465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD69_23470	COG5002	protein histidine kinase activity
TD69_23475	COG0745	RESPONSE REGULATOR receiver
TD69_23495	COG0538	isocitrate dehydrogenase activity
TD69_23500	COG0372	Belongs to the citrate synthase family
TD69_23515	COG0628	permease
TD69_23520	COG3030	protein affecting phage T7 exclusion by the F plasmid
TD69_23545	COG1725	Transcriptional regulator
TD69_23550	COG0281	malic enzyme
TD69_23555	COG0587	DNA-directed DNA polymerase activity
TD69_23570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TD69_23590	COG4109	DRTGG domain
TD69_23605	COG0006	proline dipeptidase activity
TD69_23640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_23645	COG0662	Cupin 2, conserved barrel domain protein
TD69_23655	COG1476	TRANSCRIPTIONal
TD69_23670	COG1028	Short-chain dehydrogenase reductase Sdr
TD69_23675	COG0589	response to stress
TD69_23715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_23735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TD69_23740	COG0827	DNA restriction-modification system
TD69_23745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TD69_23750	COG3874	Sporulation protein YtfJ
TD69_23760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD69_23765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TD69_23775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD69_23790	COG1104	cysteine desulfurase activity
TD69_23800	COG0583	DNA-binding transcription factor activity
TD69_23805	COG0697	spore germination
TD69_23815	COG1956	GAF domain-containing protein
TD69_23820	COG0626	cystathionine gamma-synthase activity
TD69_23840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD69_23850	COG1595	DNA-templated transcription, initiation
TD69_23860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD69_23865	COG0454	-acetyltransferase
TD69_23870	COG0517	IMP dehydrogenase activity
TD69_23875	COG0123	including yeast histone deacetylase and acetoin utilization protein
TD69_23885	COG0745	RESPONSE REGULATOR receiver
TD69_23895	COG0666	response to abiotic stimulus
TD69_23930	COG1609	Transcriptional regulator
TD69_23940	COG4851	CamS sex pheromone cAM373 precursor
TD69_23945	COG3118	belongs to the thioredoxin family
TD69_23955	COG2309	aminopeptidase activity
TD69_23975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_23990	COG1674	ftsk spoiiie
TD69_24000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_24005	COG4848	Belongs to the UPF0354 family
TD69_24010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD69_24015	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
TD69_24020	COG1363	Peptidase, m42
TD69_24030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_24045	COG0510	thiamine kinase activity
TD69_24050	COG1523	belongs to the glycosyl hydrolase 13 family
TD69_24065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD69_24070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD69_24075	COG1349	DNA-binding transcription factor activity
TD69_24080	COG1187	pseudouridine synthase activity
TD69_24085	COG2244	polysaccharide biosynthetic process
TD69_24090	COG2081	HI0933 family
TD69_24095	COG2814	Major facilitator Superfamily
TD69_24105	COG3832	glyoxalase III activity
TD69_24125	COG1329	Transcriptional regulator
TD69_24135	COG4975	Glucose uptake
TD69_24150	COG0314	molybdopterin synthase activity
TD69_24155	COG1763	Mo-molybdopterin cofactor biosynthetic process
TD69_24160	COG0303	'Molybdopterin
TD69_24170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD69_24195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD69_24205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TD69_24250	COG2814	Major facilitator Superfamily
TD69_24255	COG0475	glutathione-regulated potassium exporter activity
TD69_24260	COG0490	domain, Protein
TD69_24265	COG0582	viral genome integration into host DNA
TD69_24275	COG1136	(ABC) transporter
TD69_24295	COG1242	4 iron, 4 sulfur cluster binding
TD69_24300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TD69_24305	COG1131	(ABC) transporter
TD69_24315	COG1794	racemase activity, acting on amino acids and derivatives
TD69_24335	COG2267	carboxylic ester hydrolase activity
TD69_24340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
TD69_24345	COG0671	phosphoesterase, PA-phosphatase related
TD69_24350	COG0438	transferase activity, transferring glycosyl groups
TD69_24360	COG0521	Mo-molybdopterin cofactor biosynthetic process
TD69_24415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TD69_24420	COG5002	protein histidine kinase activity
TD69_24425	COG4191	Histidine kinase
TD69_24430	COG2267	carboxylic ester hydrolase activity
TD69_24450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD69_24455	COG1116	anion transmembrane transporter activity
TD69_24460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD69_24485	COG0494	nUDIX hydrolase
TD69_24515	COG0288	reversible hydration of carbon dioxide
TD69_24520	COG1271	oxidase subunit
TD69_24525	COG1294	oxidase, subunit
TD69_24545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_24570	COG1842	Phage shock protein A
TD69_24605	COG5002	protein histidine kinase activity
TD69_24610	COG0745	RESPONSE REGULATOR receiver
TD69_24640	COG1597	lipid kinase activity
TD69_24675	COG0586	Pfam SNARE associated Golgi protein
TD69_24685	COG0577	efflux transmembrane transporter activity
TD69_24690	COG1136	(ABC) transporter
TD69_24695	COG3708	Transcriptional regulator
TD69_24695	COG2207	Transcriptional regulator
TD69_24700	COG0745	RESPONSE REGULATOR receiver
TD69_24705	COG2205	protein histidine kinase activity
TD69_24710	COG0577	efflux transmembrane transporter activity
TD69_24720	COG0577	efflux transmembrane transporter activity
TD69_24725	COG0577	efflux transmembrane transporter activity
TD69_24730	COG1136	(ABC) transporter
TD69_24770	COG3964	amidohydrolase
TD69_24800	COG4948	Mandelate Racemase Muconate Lactonizing
TD69_24810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TD69_24815	COG0596	Alpha beta hydrolase
TD69_24820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TD69_24825	COG1169	isochorismate synthase
TD69_24830	COG1575	Belongs to the MenA family. Type 1 subfamily
TD69_24835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD69_24840	COG1278	Cold shock
TD69_24860	COG0058	SHG alpha-glucan phosphorylase activity
TD69_24865	COG0297	glycogen (starch) synthase activity
TD69_24870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD69_24875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD69_24885	COG0039	L-malate dehydrogenase activity
TD69_24980	COG0544	peptidyl-prolyl cis-trans isomerase activity
TD69_25015	COG1285	pathogenesis
TD69_25020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TD69_25030	COG0166	Belongs to the GPI family
TD69_25040	COG2155	Conserved Protein
TD69_25045	COG1098	S1 RNA binding domain
TD69_25050	COG0436	Aminotransferase
TD69_25055	COG1522	sequence-specific DNA binding
TD69_25060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD69_25065	COG2267	carboxylic ester hydrolase activity
TD69_25075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TD69_25095	COG5018	Exonuclease
TD69_25100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TD69_25115	COG0423	glycine-tRNA ligase activity
TD69_25120	COG2050	protein possibly involved in aromatic compounds catabolism
TD69_25130	COG1268	BioY protein
TD69_25140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TD69_25145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TD69_25160	COG3584	3D domain protein
TD69_25175	COG1252	NADH dehydrogenase
TD69_25190	COG3708	Transcriptional regulator
TD69_25205	COG1683	Conserved Protein
TD69_25225	COG0316	Belongs to the HesB IscA family
TD69_25240	COG1252	NADH dehydrogenase
TD69_25255	COG0390	transport system, permease component
TD69_25260	COG2824	Alkylphosphonate utilization operon protein PhnA
TD69_25300	COG4837	Protein of unknown function (DUF1462)
TD69_25305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TD69_25315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD69_25320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TD69_25335	COG2249	NAD(P)H dehydrogenase (quinone) activity
TD69_25340	COG0647	UMP catabolic process
TD69_25350	COG2445	Protein of unknown function DUF86
TD69_25355	COG1494	fructose-1,6-bisphosphatase
TD69_25375	COG4470	Protein conserved in bacteria
TD69_25385	COG0789	Transcriptional regulator
TD69_25390	COG4377	Putative membrane peptidase family (DUF2324)
TD69_25415	COG0739	heme binding
TD69_25425	COG3377	Domain of unknown function (DUF1805)
TD69_25430	COG0737	Belongs to the 5'-nucleotidase family
TD69_25440	COG1695	Transcriptional regulator
TD69_25455	COG0719	Fe-S assembly protein
TD69_25460	COG0822	iron-sulfur transferase activity
TD69_25465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TD69_25470	COG0719	Fe-S assembly protein
TD69_25475	COG0396	ATPase activity
TD69_25480	COG1464	Belongs to the NlpA lipoprotein family
TD69_25485	COG1464	Belongs to the NlpA lipoprotein family
TD69_25490	COG2011	ABC-type metal ion transport system permease component
TD69_25495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TD69_25510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD69_25515	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD69_25525	COG1393	Belongs to the ArsC family
TD69_25575	COG0039	L-malate dehydrogenase activity
TD69_25600	COG1309	transcriptional regulator
TD69_25605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD69_25610	COG1960	acyl-CoA dehydrogenase activity
TD69_25620	COG0183	Belongs to the thiolase family
TD69_25625	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD69_25625	COG1024	Enoyl-CoA hydratase
TD69_25635	COG1686	Belongs to the peptidase S11 family
TD69_25650	COG0011	TIGRFAM Protein of
TD69_25655	COG0840	transmembrane signaling receptor activity
TD69_25675	COG2814	Major facilitator Superfamily
TD69_25680	COG0531	amino acid
TD69_25690	COG0706	membrane insertase activity
TD69_25700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD69_25735	COG0586	Pfam SNARE associated Golgi protein
TD69_25745	COG1376	ErfK ybiS ycfS ynhG family protein
TD69_25750	COG0745	RESPONSE REGULATOR receiver
TD69_25755	COG5002	protein histidine kinase activity
TD69_25765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD69_25780	COG2151	metal-sulfur cluster biosynthetic enzyme
TD69_25785	COG3227	Zinc metalloprotease (Elastase)
TD69_25790	COG1741	Belongs to the pirin family
TD69_25805	COG0475	glutathione-regulated potassium exporter activity
TD69_25810	COG0490	domain, Protein
TD69_25820	COG1115	amino acid carrier protein
TD69_25825	COG0783	Belongs to the Dps family
TD69_25840	COG1611	Belongs to the LOG family
TD69_25855	COG2311	Membrane
TD69_25865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_25870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_25875	COG1115	amino acid carrier protein
TD69_25880	COG1115	amino acid carrier protein
TD69_25885	COG2910	NAD(P)H-binding
TD69_25900	COG0656	L-ascorbic acid biosynthetic process
TD69_25905	COG2814	Major facilitator Superfamily
TD69_25910	COG1733	regulation of RNA biosynthetic process
TD69_25920	COG1252	NADH dehydrogenase
TD69_25925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD69_25930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TD69_25940	COG3290	protein histidine kinase activity
TD69_25940	COG0840	transmembrane signaling receptor activity
TD69_25950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD69_25955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD69_25970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD69_25975	COG3223	Belongs to the PsiE family
TD69_26020	COG0557	exoribonuclease II activity
TD69_26025	COG1647	Serine aminopeptidase, S33
TD69_26030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD69_26035	COG1346	cytolysis
TD69_26135	COG4695	Portal protein
TD69_26160	COG4974	Belongs to the 'phage' integrase family
TD69_26170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TD69_26175	COG0149	triose-phosphate isomerase activity
TD69_26185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD69_26200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
TD69_26225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD69_26240	COG2323	membrane
TD69_26245	COG0740	serine-type endopeptidase activity
TD69_26250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD69_26260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TD69_26270	COG1051	belongs to the nudix hydrolase family
TD69_26280	COG0492	ferredoxin-NADP+ reductase activity
TD69_26285	COG0457	Tetratricopeptide repeat
TD69_26290	COG0110	maltose O-acetyltransferase activity
TD69_26310	COG1950	PFAM Membrane protein of
TD69_26320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TD69_26325	COG0556	nucleotide-excision repair
TD69_26345	COG0789	Transcriptional regulator
TD69_26370	COG2855	membrane
TD69_26375	COG0583	DNA-binding transcription factor activity
TD69_26385	COG0655	NAD(P)H dehydrogenase (quinone) activity
TD69_26400	COG1132	(ABC) transporter
TD69_26405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD69_26410	COG0793	Belongs to the peptidase S41A family
TD69_26410	COG3409	Peptidoglycan-binding domain 1 protein
TD69_26415	COG2177	Part of the ABC transporter FtsEX involved in
TD69_26420	COG2884	Cell division ATP-binding protein ftsE
TD69_26435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TD69_26440	COG0653	protein targeting
TD69_26445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TD69_26450	COG1278	Cold shock
TD69_26455	COG1040	competence protein
TD69_26460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
TD69_26465	COG0791	NLP P60 protein
TD69_26465	COG1388	LysM domain
TD69_26470	COG1733	regulation of RNA biosynthetic process
TD69_26480	COG1307	EDD domain protein, DegV family
TD69_26485	COG1739	Uncharacterized protein family UPF0029
TD69_26490	COG1316	TRANSCRIPTIONal
TD69_26495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TD69_26500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD69_26505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TD69_26515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TD69_26515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TD69_26530	COG3394	polysaccharide catabolic process
TD69_26535	COG1486	melibiose metabolic process
TD69_26540	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD69_26545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD69_26555	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TD69_26560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TD69_26565	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD69_26575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD69_26580	COG1301	dicarboxylic acid transport
TD69_26590	COG0346	lactoylglutathione lyase activity
TD69_26595	COG1511	domain protein
TD69_26600	COG0583	DNA-binding transcription factor activity
TD69_26605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
TD69_26625	COG1271	oxidase subunit
TD69_26630	COG1294	oxidase, subunit
TD69_26635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TD69_26645	COG1620	l-lactate permease
TD69_26655	COG2389	metal-binding protein
TD69_26665	COG1368	sulfuric ester hydrolase activity
TD69_26680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD69_26700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TD69_26705	COG3584	3D domain protein
TD69_26705	COG1388	LysM domain
TD69_26730	COG4715	Zinc finger, swim domain protein
TD69_26735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD69_26765	COG1191	sigma factor activity
TD69_26775	COG0577	efflux transmembrane transporter activity
TD69_26780	COG1136	(ABC) transporter
TD69_26815	COG5002	protein histidine kinase activity
TD69_26820	COG0745	RESPONSE REGULATOR receiver
TD69_26825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TD69_26845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TD69_26850	COG1134	teichoic acid transport
TD69_26855	COG1682	transport, permease protein
TD69_26860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TD69_26905	COG1609	Transcriptional regulator
TD69_26920	COG0739	heme binding
TD69_26935	COG3279	Response regulator of the LytR AlgR family
TD69_26940	COG4555	ABC transporter
TD69_26945	COG2385	sporulation resulting in formation of a cellular spore
TD69_26950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD69_26960	COG4836	Membrane
TD69_26965	COG1007	ATP synthesis coupled electron transport
TD69_26970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TD69_26975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD69_26985	COG0839	Belongs to the complex I subunit 6 family
TD69_27000	COG0649	NAD binding
TD69_27005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TD69_27015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TD69_27020	COG3300	MHYT domain
TD69_27020	COG5001	Diguanylate cyclase
TD69_27070	COG0356	it plays a direct role in the translocation of protons across the membrane
TD69_27105	COG0698	ribose 5-phosphate isomerase
TD69_27115	COG2190	(PTS) system
TD69_27120	COG2259	Doxx family
TD69_27125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TD69_27140	COG0009	L-threonylcarbamoyladenylate synthase
TD69_27155	COG2890	protein-(glutamine-N5) methyltransferase activity
TD69_27160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TD69_27175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TD69_27180	COG1494	fructose-1,6-bisphosphatase
TD69_27185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD69_27200	COG4821	SIS domain
TD69_27210	COG3343	RNA polymerase activity
TD69_27220	COG1960	acyl-CoA dehydrogenase activity
TD69_27225	COG1960	acyl-CoA dehydrogenase activity
TD69_27230	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD69_27235	COG0183	Belongs to the thiolase family
TD69_27240	COG0247	lactate metabolic process
TD69_27240	COG2181	nitrate reductase activity
TD69_27245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD69_27255	COG5001	Diguanylate cyclase
TD69_27255	COG3300	MHYT domain
TD69_27270	COG2197	response regulator
TD69_27275	COG4585	Histidine kinase
TD69_27280	COG0842	Transport permease protein
TD69_27285	COG1131	(ABC) transporter
TD69_27290	COG0024	Methionine aminopeptidase
TD69_27310	COG2234	aminopeptidase activity
TD69_27330	COG1595	DNA-templated transcription, initiation
TD69_27335	COG0018	arginyl-trna synthetase
TD69_27340	COG4506	Protein conserved in bacteria
TD69_27345	COG1619	proteins homologs of microcin C7 resistance protein MccF
TD69_27365	COG0010	Belongs to the arginase family
TD69_27370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TD69_27375	COG2814	Major facilitator Superfamily
TD69_27380	COG0789	Transcriptional regulator
TD69_27385	COG0584	glycerophosphoryl diester phosphodiesterase
TD69_27390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD69_27400	COG1994	Peptidase M50
TD69_27410	COG1078	dGTPase activity
TD69_27415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD69_27420	COG1120	ATPase activity
TD69_27425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_27430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_27435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD69_27455	COG0095	Lipoate-protein ligase
TD69_27460	COG0280	phosphate acetyltransferase
TD69_27475	COG3773	Cell wall hydrolase
TD69_27485	COG2363	Small membrane protein
TD69_27500	COG2233	PERMEase
TD69_27505	COG0561	phosphatase activity
TD69_27510	COG2814	Major facilitator Superfamily
TD69_27520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD69_27525	COG1131	(ABC) transporter
TD69_27530	COG2755	lipolytic protein G-D-S-L family
TD69_27535	COG1609	Transcriptional regulator
TD69_27545	COG0460	homoserine dehydrogenase
TD69_27565	COG1011	Hydrolase
TD69_27570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD69_27580	COG2197	response regulator
TD69_27590	COG0351	phosphomethylpyrimidine kinase
TD69_27595	COG3706	GGDEF domain
TD69_27600	COG2879	small protein
TD69_27605	COG1966	Carbon starvation protein
TD69_27610	COG3279	Response regulator of the LytR AlgR family
TD69_27615	COG0477	Major facilitator Superfamily
TD69_27640	COG0840	transmembrane signaling receptor activity
TD69_27650	COG1607	acyl-coa hydrolase
TD69_27665	COG0488	(ABC) transporter
TD69_27690	COG0463	Glycosyl transferase, family 2
TD69_27695	COG1309	transcriptional regulator
TD69_27700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TD69_27705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TD69_27705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TD69_27710	COG0628	permease
TD69_27725	COG3279	Response regulator of the LytR AlgR family
TD69_27730	COG3275	phosphorelay sensor kinase activity
TD69_27735	COG2814	Major facilitator Superfamily
TD69_27740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TD69_27745	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
TD69_27750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD69_27770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TD69_27775	COG1272	protein, Hemolysin III
TD69_27795	COG0516	GMP reductase activity
TD69_27800	COG1164	Oligoendopeptidase f
TD69_27820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD69_27825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TD69_27830	COG4853	Protein conserved in bacteria
TD69_27835	COG4863	YycH protein
TD69_27840	COG5002	protein histidine kinase activity
TD69_27845	COG0745	RESPONSE REGULATOR receiver
TD69_27875	COG0305	Participates in initiation and elongation during chromosome replication
TD69_27885	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TD69_27890	COG4241	membrane
TD69_27900	COG0629	single-stranded DNA binding
TD69_27910	COG0012	GTP binding
TD69_27915	COG4481	Protein conserved in bacteria
TD69_27920	COG0668	transmembrane transport
TD69_27930	COG1475	DNA binding
TD69_27935	COG1192	Involved in chromosome partitioning
TD69_27955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TD69_27960	COG1847	R3H domain protein
TD69_27965	COG0706	membrane insertase activity
TD69_28025	COG3344	reverse transcriptase
TD69_28105	COG3344	reverse transcriptase
TD69_28310	COG4962	Type ii secretion system protein e
TD69_28445	COG2311	Membrane
TD69_28470	COG4196	transglutaminase domain protein
TD69_28475	COG0671	phosphoesterase, PA-phosphatase related
TD69_28500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TD69_28505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD69_28520	COG2801	Transposase and inactivated derivatives
TD69_28675	COG2002	toxin-antitoxin pair type II binding
TD69_28685	COG4974	Belongs to the 'phage' integrase family
TD69_28725	COG2801	Transposase and inactivated derivatives
TD69_28745	COG3443	Belongs to the bacterial solute-binding protein 9 family
TD69_28755	COG4974	Belongs to the 'phage' integrase family
TD69_28780	COG0457	Tetratricopeptide repeat
TD69_28785	COG1923	regulation of RNA biosynthetic process
TD69_28865	COG0791	NLP P60 protein
TD69_28865	COG0741	lytic transglycosylase activity
TD69_29010	COG1192	Involved in chromosome partitioning
TD69_29055	COG1683	Conserved Protein
TD69_29060	COG1309	transcriptional regulator
TD69_29120	COG0681	Belongs to the peptidase S26 family
TD69_29150	COG1280	lysine exporter protein (LysE YggA)
TD69_29190	COG4166	transmembrane transport
TD69_29205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD69_29265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD69_29270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone