locus-tag class description BG01_1006 ENOG4105CGH 5'-nucleotidase BG01_1007 ENOG4105DFD Na H antiporter BG01_1009 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG01_1011 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BG01_1012 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BG01_1013 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BG01_1014 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BG01_1018 ENOG4108R6K riboflavin synthase, subunit alpha BG01_1019 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BG01_1023 ENOG4108YM7 Gcn5-related n-acetyltransferase BG01_1027 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BG01_103 ENOG4105CXN decarboxylase BG01_1031 ENOG4105RHY Pfam:UPF0157 BG01_1033 ENOG4105CPC Aldo Keto reductase BG01_1037 ENOG4105MZ9 stage II sporulation protein m BG01_1038 ENOG4105I3K Ferric uptake regulator, Fur family BG01_1040 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG01_1045 ENOG4105D7N magnesium and cobalt transport protein CorA BG01_105 ENOG4105FA2 dna polymerase iii BG01_1051 ENOG4105DVE abc transporter atp-binding protein BG01_1052 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG01_1053 ENOG4105DZ1 carboxypeptidase BG01_1054 ENOG41082AN stage II sporulation protein BG01_1056 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_1057 ENOG4105C8J )-transporter BG01_106 ENOG4105MA4 psp1 domain protein BG01_1061 ENOG41090VF Stage v sporulation protein ac BG01_1062 ENOG4105CZ3 stage V sporulation protein ad BG01_1064 ENOG4105G6R Stage v sporulation protein ae BG01_1066 ENOG4105J7I hydrolase BG01_1067 ENOG4105PTM secreted protein BG01_1068 ENOG4107ZE5 PPIases accelerate the folding of proteins BG01_1075 ENOG4105CE4 GlcNAc 6-P deacetylase BG01_1077 ENOG4105FDP GntR family transcriptional regulator BG01_1079 ENOG4105CID antiterminator BG01_108 ENOG41060K3 Methyltransferase BG01_1082 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BG01_1086 ENOG4106TD9 Diguanylate cyclase BG01_1087 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG01_1088 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG01_1091 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BG01_1096 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BG01_1098 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BG01_110 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BG01_1100 ENOG4105DTD Dehydrogenase BG01_1101 ENOG4105K7K Transcriptional regulator BG01_1108 ENOG4105CHU acetyl-coa acetyltransferase BG01_111 ENOG4105KRN Transcriptional regulator, abrb family BG01_1117 ENOG4105CG3 alpha amylase, catalytic region BG01_1119 ENOG4107FKK extracellular solute-binding protein family 1 BG01_1121 ENOG4105EG2 ABC transporter, permease BG01_1122 ENOG4105FKQ transcriptional regulator BG01_1123 ENOG4105CHM Aminotransferase BG01_1125 ENOG4108HGU Histidine kinase BG01_113 ENOG4105F8V Hydrolase, tatD family BG01_1136 ENOG4105UIN BG01_1138 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BG01_114 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BG01_1141 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BG01_1142 ENOG4105EPM Diguanylate phosphodiesterase BG01_1145 ENOG4107IN1 Protein of unknown function (DUF1797) BG01_1147 ENOG4108XRC Protein of unknown function (DUF458) BG01_1154 ENOG4107ZYR domain protein BG01_1155 ENOG4105CN5 Metallo-Beta-Lactamase BG01_1157 ENOG4108X4Q Hydrolase BG01_1158 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BG01_116 ENOG4105XFA sporulation peptidase YabG BG01_1161 ENOG4105CPP Dehydrogenase, E1 component BG01_1162 ENOG4105C7S Dehydrogenase BG01_117 ENOG4105W42 Veg protein BG01_1171 ENOG4105CXN decarboxylase BG01_1175 ENOG4105ECY inositol monophosphatase BG01_1177 ENOG4105CI3 gtp-binding protein typa BG01_1178 ENOG4105QA2 BG01_1182 ENOG4108IAB Phoh family BG01_1185 ENOG4105CNI cell division protein FtsW BG01_1186 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BG01_1196 ENOG4106UY4 Inherit from COG: Scp-like extracellular BG01_1199 ENOG4107TB6 phosphoglycerate mutase BG01_120 ENOG4105DFT pur operon repressor BG01_1204 ENOG4106H78 methyltransferase BG01_1205 ENOG4105H20 Sporulation integral membrane protein YlbJ BG01_1207 ENOG4105D78 K07001 NTE family protein BG01_1208 ENOG41063PX domain protein BG01_121 ENOG4105KME endoribonuclease L-psp BG01_1210 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BG01_1218 ENOG4108IMY Transcriptional regulator BG01_1229 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_1232 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BG01_124 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BG01_1249 ENOG4105CAR Terminase, large subunit BG01_125 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BG01_1251 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BG01_1268 ENOG4105XSJ toxin secretion phage lysis holin BG01_127 ENOG4108JA2 transcriptioN-repair coupling factor BG01_1278 ENOG4105KNH Nucleic acid-binding protein BG01_128 ENOG4108M14 stage v sporulation protein t BG01_1285 ENOG41068DC Essential cell division protein (By similarity) BG01_1286 ENOG4105CJN penicillin-binding protein BG01_1287 ENOG4105CJN penicillin-binding protein BG01_1288 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG01_1291 ENOG4105CNI cell division protein FtsW BG01_1292 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BG01_1293 ENOG4105D4A Cell wall formation (By similarity) BG01_1294 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BG01_1295 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BG01_1296 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BG01_1298 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_13 ENOG4105CKK Glycosyl transferase, family 2 BG01_130 ENOG4108IY2 MazG family BG01_1300 ENOG4105WR5 sporulation protein, YlmC YmxH family BG01_1301 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BG01_1302 ENOG4105DFA alanine racemase domain protein BG01_1304 ENOG41067XK integral membrane protein BG01_1305 ENOG4105DBK s4 domain protein BG01_1307 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BG01_131 ENOG41082I2 s4 domain protein BG01_1310 ENOG4105C34 Pseudouridine synthase BG01_1315 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BG01_132 ENOG4105VYY sporulation protein yabp BG01_1326 ENOG4105DC7 peptidase M24 BG01_1327 ENOG4105F23 Fibronectin-binding protein BG01_1329 ENOG4105DSJ YicC domain protein BG01_1333 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BG01_1334 ENOG4105C25 Primosomal protein n' BG01_1335 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BG01_1337 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BG01_1339 ENOG4108ZF3 Phosphatase BG01_1340 ENOG4105D9P serine threonine protein kinase BG01_1341 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BG01_1342 ENOG4105DJV ribulose-phosphate 3-epimerase BG01_1343 ENOG4105FJ0 thiamine BG01_1345 ENOG4108ZAA Alkaline-shock protein BG01_1346 ENOG4105DP4 dak2 domain fusion protein ylov BG01_1347 ENOG4105CB5 ATP-dependent DNA helicase recG BG01_135 ENOG41060GV RNA binding s1 domain protein BG01_1350 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BG01_1351 ENOG4105CHR reductase BG01_1354 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BG01_1355 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BG01_1359 ENOG4105VB6 UPF0109 protein BG01_1364 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BG01_1367 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BG01_1369 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG01_1371 ENOG4108HE4 integrase family BG01_1379 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BG01_1380 ENOG4105KNE Phosphatidate cytidylyltransferase BG01_1381 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BG01_1382 ENOG4105DZP Membrane-associated zinc metalloprotease BG01_1384 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BG01_1386 ENOG4105CHV Transcription elongation factor NusA BG01_1387 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BG01_1388 ENOG4105VHM ribosomal protein BG01_139 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BG01_1390 ENOG4105W7A Protein of unknown function (DUF503) BG01_1392 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BG01_1393 ENOG4105DTN riboflavin biosynthesis protein ribF BG01_1397 ENOG4105C1V Peptidase, M16 BG01_1399 ENOG4105E35 Dipicolinate synthase subunit A BG01_14 ENOG41067SE Tetr family transcriptional regulator BG01_140 ENOG4108UGV hypoxanthine phosphoribosyltransferase BG01_1400 ENOG4108S0H Dipicolinic acid synthetase, b subunit BG01_1401 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BG01_1403 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BG01_1405 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BG01_1407 ENOG4107QZI cell division protein FtsK BG01_1408 ENOG4105FDP GntR family transcriptional regulator BG01_1409 ENOG4105DIH basic membrane BG01_141 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BG01_1410 ENOG4108JQ9 ABC transporter BG01_1411 ENOG4105UIB (ABC) transporter BG01_1412 ENOG4105UIB (ABC) transporter BG01_1416 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BG01_1417 ENOG4105XZV Protein of unknown function (DUF3243) BG01_1420 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BG01_1425 ENOG4105D48 metallophosphoesterase BG01_1426 ENOG4105MCT stage V sporulation protein S BG01_1427 ENOG4108IGT Dipeptidase BG01_1428 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BG01_1429 ENOG4105DQU oxidoreductase, subunit beta BG01_1430 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BG01_1435 ENOG4105DA5 (ABC) transporter BG01_144 ENOG4105C6T cysteine synthase BG01_1440 ENOG4107QHE Choloylglycine hydrolase BG01_1442 ENOG410890F Dynamin family BG01_1443 ENOG4105E0M Sulfatase BG01_1444 ENOG4107R6R udp-galactopyranose mutase BG01_1445 ENOG4105F0V Cell wall hydrolase BG01_1449 ENOG4107YEI lmbE family BG01_145 ENOG4105CRQ synthase (Component I) BG01_1450 ENOG4107TTQ Alpha beta hydrolase fold BG01_1453 ENOG41067MG lrgb family BG01_1456 ENOG4105BZU Histidine kinase BG01_1457 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_146 ENOG4105DDQ anthranilate synthase BG01_1463 ENOG4105D03 DNA-3-methyladenine glycosylase II BG01_1464 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BG01_1466 ENOG4105CGK Exodeoxyribonuclease III BG01_147 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BG01_1471 ENOG4105E0A ABC, transporter BG01_1472 ENOG4105NIV Esterase BG01_1474 ENOG4105VPX protein, conserved in bacteria BG01_1475 ENOG410681U heavy metal transport detoxification protein BG01_1476 ENOG4105C59 p-type ATPase BG01_1477 ENOG4105K70 DNA-binding protein BG01_1478 ENOG4105TMB Formate nitrite transporter BG01_148 ENOG4105EEI dihydropteroate synthase BG01_1482 ENOG4105C85 amino acid BG01_1485 ENOG4108SJC Membrane BG01_1486 ENOG4107QW4 alcohol dehydrogenase BG01_1487 ENOG4107QW4 alcohol dehydrogenase BG01_1488 ENOG4105E98 transcriptional regulator DeoR family BG01_1489 ENOG4105DE4 1-phosphofructokinase BG01_149 ENOG4105KRF dihydroneopterin aldolase BG01_1490 ENOG4105DM4 PTS System BG01_1491 ENOG41069ER domain protein BG01_1498 ENOG4106F1P AAA ATPase, central domain protein BG01_1499 ENOG4105EN6 Membrane BG01_150 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BG01_1500 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG01_1501 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG01_1502 ENOG4105CXI aluminum resistance protein BG01_1503 ENOG4105KV4 Transcriptional regulator BG01_1504 ENOG4105C5F glutamine synthetase BG01_152 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BG01_1525 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BG01_1565 ENOG4105XSJ toxin secretion phage lysis holin BG01_1566 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BG01_1574 ENOG4105K7K Transcriptional regulator BG01_1578 ENOG4108SVB resolvase BG01_1580 ENOG4105CGH 5'-nucleotidase BG01_1583 ENOG4105D5T phosphonate abc transporter BG01_1586 ENOG4105D7V transposase BG01_159 ENOG4108Z0C Uvrb UvrC protein BG01_1590 ENOG4105BZ1 (ABC) transporter BG01_1591 ENOG4105BZ1 (ABC) transporter BG01_1594 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG01_1599 ENOG41067MG lrgb family BG01_16 ENOG4105E0X reductase BG01_1600 ENOG4105VAW lrga family BG01_1601 ENOG4107RSM transcriptional regulator BG01_1603 ENOG4107QIV Cytochrome c biogenesis protein BG01_1614 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BG01_1619 ENOG4108903 Formimidoylglutamase BG01_162 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BG01_1620 ENOG4108VJ1 Transcriptional regulator (CarD family BG01_1621 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BG01_1622 ENOG4105CBC glutamate synthase BG01_1623 ENOG4105CK7 Sodium proline symporter BG01_1624 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BG01_1625 ENOG4105FBA Phospholipase Carboxylesterase BG01_1626 ENOG4105BZU Histidine kinase BG01_1628 ENOG4107AYK membrAne BG01_1637 ENOG4105CEY Amp-dependent synthetase and ligase BG01_1638 ENOG4107ZYJ bioY protein BG01_1639 ENOG4107F3J Amp-dependent synthetase and ligase BG01_164 ENOG4105CTP PilT protein domain protein BG01_1643 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG01_1645 ENOG4105E5W Transporter BG01_1650 ENOG4108I0Z Aconitate hydratase BG01_1651 ENOG4108JJA ABC, transporter BG01_1653 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BG01_1654 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BG01_1660 ENOG4105W8X HesB YadR YfhF-family protein BG01_1661 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BG01_1662 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BG01_1664 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_1665 ENOG4105C0H protease BG01_1666 ENOG4105K4P CoA-binding domain protein BG01_1667 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BG01_1669 ENOG4105D9R oxidoreductase BG01_1671 ENOG4105CIG ABC transporter BG01_1675 ENOG4105EMN RNA polymerase sigma factor BG01_1677 ENOG4108KGH TRANSCRIPTIONal BG01_1678 ENOG4107QJT sodium dicarboxylate symporter BG01_168 ENOG4105D7W serine acetyltransferase BG01_1690 ENOG4105E1K spore germination protein BG01_1692 ENOG4108JB9 formate dehydrogenase BG01_1694 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BG01_1695 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BG01_1697 ENOG4105TMB Formate nitrite transporter BG01_1698 ENOG4105D06 uba thif-type nad fad binding protein BG01_1699 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG01_17 ENOG4106F5Q Membrane BG01_1700 ENOG4108ZAF Molybdopterin BG01_1702 ENOG4105D1F ATP-binding protein BG01_1705 ENOG410696E Membrane BG01_1706 ENOG4105FR1 rard protein BG01_1708 ENOG4105EWU Squalene--hopene cyclase BG01_171 ENOG4105C2N RNA methyltransferase TrmH family group 3 BG01_1710 ENOG4105CHR reductase BG01_1711 ENOG4105C26 Dehydrogenase BG01_1713 ENOG4108IA2 Sodium pantothenate symporter BG01_1716 ENOG4106IQC argininosuccinate lyase BG01_1718 ENOG410904N short-chain dehydrogenase reductase BG01_172 ENOG4105M0M Tetracycline resistance protein BG01_1723 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BG01_1727 ENOG4105VEQ Cold shock protein BG01_173 ENOG4105QIV RNA polymerase BG01_1731 ENOG4108R1P BG01_1733 ENOG41073R8 VanW family BG01_1734 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_1736 ENOG4105KT7 mgtC SapB transporter BG01_1738 ENOG4105E39 Enoyl-CoA hydratase BG01_1739 ENOG4105K64 Glycosyl transferase, family 2 BG01_1741 ENOG4108UT6 Transferase hexapeptide repeat containing protein BG01_1745 ENOG4105CQB FAD linked oxidase domain protein BG01_1746 ENOG4105C09 Bile acid BG01_1748 ENOG4105RHY Pfam:UPF0157 BG01_175 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BG01_1754 ENOG4105CIS alcohol dehydrogenase BG01_1755 ENOG41082BM Transcriptional regulator, arsr family BG01_1759 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BG01_1765 ENOG4108A04 Beta-lactamase BG01_1766 ENOG4105DPN Oligoendopeptidase f BG01_1767 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BG01_1768 ENOG4105E5K Alpha-amylase BG01_1770 ENOG4105C98 muts2 protein BG01_1774 ENOG4107V2S Transcriptional regulator BG01_1776 ENOG4107CUJ Protein of unknown function (DUF2690) BG01_1780 ENOG4107ZY0 Phenazine biosynthesis-like protein BG01_1781 ENOG4105NX3 Membrane BG01_1782 ENOG4105DQ5 transport system permease protein BG01_1783 ENOG4105EHG Permease protein BG01_1785 ENOG4108MES Periplasmic binding protein BG01_1789 ENOG4107R3E Citrate transporter BG01_1791 ENOG4108TN2 lmbE family BG01_1798 ENOG4105CIS alcohol dehydrogenase BG01_180 ENOG4107Y49 methyltransferase BG01_1805 ENOG4105H3G oxidoreductase BG01_1807 ENOG4105ED2 Beta-lactamase BG01_1812 ENOG4107YXZ hydrolase, family 25 BG01_1816 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BG01_182 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BG01_1821 ENOG4105KAF membrAne BG01_183 ENOG4105XPM ribosomal protein BG01_1831 ENOG4108ZJ4 polysaccharide deacetylase BG01_1835 ENOG4105KVH Transcriptional regulator BG01_1836 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BG01_1840 ENOG4105CHR reductase BG01_1842 ENOG4105JAB phenazine biosynthesis protein, phzf family BG01_1849 ENOG4105KVH Transcriptional regulator BG01_1850 ENOG4105KVH Transcriptional regulator BG01_1851 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BG01_1853 ENOG4105D9R oxidoreductase BG01_1854 ENOG4108TZY GntR Family Transcriptional Regulator BG01_1855 ENOG4105KVH Transcriptional regulator BG01_1861 ENOG4105C44 Serine transporter BG01_1862 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BG01_1865 ENOG4105F27 Major Facilitator BG01_1866 ENOG4105CV8 reductase BG01_1870 ENOG4105D4Y metalloprotease BG01_1871 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BG01_1874 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BG01_1875 ENOG4105CIS alcohol dehydrogenase BG01_1876 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BG01_1877 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BG01_1880 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BG01_1881 ENOG4105C6Z Gluconate BG01_1882 ENOG4105CMG Carbohydrate kinase BG01_1883 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BG01_1884 ENOG4105XDF Protein of unknown function (DUF1272) BG01_1885 ENOG4105DDN Pentapeptide repeat-containing protein BG01_1888 ENOG4105C37 (CBS) domain BG01_1894 ENOG4105EV4 Multidrug resistance protein mdtH BG01_1896 ENOG4105DMQ Methyltransferase BG01_1901 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BG01_1902 ENOG4105C31 Tryptophanyl-tRNA synthetase BG01_1904 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BG01_1907 ENOG4108UW5 maltose o-acetyltransferase BG01_1908 ENOG4106UW1 Major Facilitator superfamily BG01_1909 ENOG4105DKQ ROK family BG01_1910 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_1922 ENOG4105CJ1 ABC, transporter BG01_1924 ENOG4108PSK reductase BG01_1928 ENOG4108RCM Nitroreductase BG01_1929 ENOG4105KVH Transcriptional regulator BG01_1932 ENOG4105CUT histidyl-tRNA synthetase BG01_1933 ENOG4108Z66 YbaK ebsC protein BG01_1935 ENOG41067QW Transcriptional regulator BG01_1938 ENOG4108K8S endonuclease I BG01_1943 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BG01_1944 ENOG4108JJB ABC transporter BG01_1950 ENOG4105DYS nad(p)h dehydrogenase (quinone) BG01_1952 ENOG4105CRW Short chain fatty acid transporter BG01_1954 ENOG4105KBX Transcriptional regulator, TetR family BG01_1955 ENOG4105KPY Small multidrug resistance protein BG01_1956 ENOG4105RXJ BG01_1958 ENOG41069JR BG01_1959 ENOG4105DA5 (ABC) transporter BG01_1963 ENOG4105CZM Major Facilitator BG01_1964 ENOG4107MII Sugar-specific transcriptional regulator TrmB BG01_1966 ENOG4108ISG Major Facilitator BG01_1974 ENOG4105HIR S-layer domain protein BG01_1977 ENOG410874W AraC family transcriptional regulator BG01_1978 ENOG41082W1 Cupin 2, conserved barrel domain protein BG01_1981 ENOG4108AEY RNA polymerase sigma factor BG01_1985 ENOG4108JQ1 Dehydrogenase BG01_1988 ENOG4105DVH amino acid BG01_1990 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BG01_1993 ENOG4108JPW Aminotransferase BG01_1995 ENOG4105EJQ L-serine dehydratase BG01_1996 ENOG4105C44 Serine transporter BG01_1999 ENOG4108JGH Tetr family transcriptional regulator BG01_2 ENOG4105EN6 Membrane BG01_20 ENOG4105DY9 regulatoR BG01_2000 ENOG4105EQ0 Major Facilitator superfamily BG01_2001 ENOG4105MZU cell filamentation protein BG01_2004 ENOG4107QJQ Mate efflux family protein BG01_2011 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG01_2019 ENOG4105TRI Hydrolase BG01_2025 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BG01_2027 ENOG4106P55 Transcriptional regulator BG01_2029 ENOG4107QR9 Iron-sulfur cluster binding protein BG01_2030 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BG01_2031 ENOG4105DJB Major Facilitator Superfamily BG01_2032 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BG01_2034 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BG01_2035 ENOG4108U05 Transcriptional regulator BG01_2038 ENOG4105BZU Histidine kinase BG01_204 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BG01_2041 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BG01_2042 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BG01_2045 ENOG4105JQZ Methyltransferase BG01_2046 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG01_2048 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BG01_2049 ENOG4108NNI Beta-lactamase domain-containing protein BG01_2052 ENOG4105VZ8 Transcriptional regulator BG01_2058 ENOG4105K6H D-cysteine desulfhydrase BG01_2063 ENOG41062D9 Histidine kinase BG01_2064 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_2067 ENOG4105IIP Membrane BG01_2069 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_2070 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BG01_2084 ENOG4108YXU transcriptional regulator AsnC family BG01_2085 ENOG4105CHR reductase BG01_2087 ENOG4105F7F Chaperone BG01_209 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BG01_2091 ENOG41085FC arsR family transcriptional regulator BG01_2092 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_2093 ENOG4105D6J arsenicaL-resistance protein BG01_2099 ENOG4105DIK (ABC) transporter BG01_21 ENOG4108HRK Histidine kinase BG01_2100 ENOG4105CC5 ABC transporter BG01_2101 ENOG4105DSE periplasmic solute binding protein BG01_2102 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BG01_2103 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BG01_2105 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BG01_2106 ENOG4108TWJ NADH dehydrogenase subunit 5 BG01_2109 ENOG4105CVP deoxyribo-dipyrimidine photolyase BG01_211 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BG01_2110 ENOG4108606 TspO/MBR family BG01_2118 ENOG41090MY MarR family Transcriptional regulator BG01_2124 ENOG4105CHJ isochorismatase hydrolase BG01_2126 ENOG4105CH6 catalase BG01_2127 ENOG4105CGH 5'-nucleotidase BG01_213 ENOG41067V7 50S ribosomal protein L36 BG01_2135 ENOG4105CSV Glutaminase BG01_2140 ENOG4108Q8B Spore germination protein BG01_2141 ENOG4108NHD germination protein BG01_2142 ENOG4108NHD germination protein BG01_2145 ENOG4105C6K Malic enzyme BG01_2147 ENOG4105II7 pyrroline-5-carboxylate reductase BG01_2149 ENOG4105CUB amino acid BG01_2150 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BG01_2152 ENOG4108IMY Transcriptional regulator BG01_2153 ENOG4105HDK L-asparaginase BG01_2154 ENOG4108IJ0 Aspartate ammonia-lyase BG01_2157 ENOG4105E2A Dehydrogenase BG01_2173 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BG01_2179 ENOG4105DWD nucleoside recognition domain protein BG01_2183 ENOG4105FDT acyl-CoA dehydrogenase BG01_2185 ENOG4108ZHR arsR family transcriptional regulator BG01_2186 ENOG4108ZRV stage ii sporulation protein p BG01_2187 ENOG4106N3A copper homeostasis protein cutc BG01_2189 ENOG4107258 Transcriptional regulator BG01_219 ENOG4108JJB ABC transporter BG01_2190 ENOG4105P4J Allophanate hydrolase, subunit 1 BG01_2197 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BG01_2199 ENOG4107RF6 penicillin-binding protein BG01_22 ENOG4107RGD Major Facilitator superfamily BG01_220 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BG01_2207 ENOG4105F1N DNA alkylation repair BG01_2209 ENOG4108IQI permease BG01_221 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BG01_2210 ENOG4105KNA -acetyltransferase BG01_2211 ENOG410635A Membrane BG01_2227 ENOG4108XET gCN5-related N-acetyltransferase BG01_2233 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BG01_2235 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG01_2242 ENOG4105FS7 Transcriptional regulator BG01_2243 ENOG4108TVJ Nitroreductase BG01_2245 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG01_2254 ENOG4105C8Y Acetylornithine aminotransferase BG01_2256 ENOG4105CKK Glycosyl transferase, family 2 BG01_226 ENOG4105D1F ATP-binding protein BG01_2261 ENOG4105CKK Glycosyl transferase, family 2 BG01_2266 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG01_2271 ENOG41068WN BG01_2273 ENOG4108WCX response regulator BG01_2275 ENOG41090T1 Membrane BG01_2278 ENOG4105VMP Transcriptional regulator BG01_2280 ENOG4105G6Z alkaline phosphatase BG01_2281 ENOG4105ECK Fatty Acid Desaturase BG01_2282 ENOG4105E0Y RtcB Protein BG01_2284 ENOG4107258 Transcriptional regulator BG01_2286 ENOG4105II7 pyrroline-5-carboxylate reductase BG01_2287 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BG01_229 ENOG4108NMV polysaccharide deacetylase BG01_2293 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BG01_2297 ENOG41061GT Aldolase BG01_2300 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BG01_2301 ENOG4105DKT Transcriptional regulator BG01_2303 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BG01_2305 ENOG4105D4B ABC, transporter BG01_2311 ENOG4105EMN RNA polymerase sigma factor BG01_2313 ENOG41069ER domain protein BG01_2321 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BG01_2322 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BG01_2323 ENOG4105CIH Imidazole acetol-phosphate transaminase BG01_2327 ENOG41082JN Transcriptional regulator BG01_2328 ENOG4105EYF MMPL domain protein BG01_2329 ENOG4105EYF MMPL domain protein BG01_2331 ENOG4105C5H ABC transporter BG01_2332 ENOG4105E0M Sulfatase BG01_2333 ENOG4108ZCF integral membrane protein BG01_2335 ENOG4107VMI polysaccharide deacetylase BG01_2337 ENOG4107VC0 DNA alkylation repair enzyme BG01_2347 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BG01_2351 ENOG4105E09 nadh pyrophosphatase BG01_2357 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BG01_2358 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BG01_2359 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BG01_2361 ENOG4105C02 permease BG01_2370 ENOG4105DVE abc transporter atp-binding protein BG01_2377 ENOG4105CHM Aminotransferase BG01_238 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BG01_2383 ENOG41089UC methyltransferase, type 11 BG01_2386 ENOG4107BMA Transglycosylase associated protein BG01_2390 ENOG4106K7D Major facilitator family transporter BG01_2391 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BG01_2399 ENOG4105EPR degv family BG01_2402 ENOG4105DPN Oligoendopeptidase f BG01_2409 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_2410 ENOG4105BZU Histidine kinase BG01_2411 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BG01_2419 ENOG4105DTQ mandelate racemase muconate lactonizing BG01_2422 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BG01_2423 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BG01_2426 ENOG4107T5V SNARE associated Golgi BG01_2433 ENOG41080HI glycine oxidase BG01_2434 ENOG4105CTU Proline racemase BG01_2435 ENOG4105CTU Proline racemase BG01_2436 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BG01_2437 ENOG4105C26 Dehydrogenase BG01_2438 ENOG4105BZG amino acid carrier protein BG01_2441 ENOG4108M1A Chitin-binding protein BG01_2449 ENOG4105C9U ATP-dependent DNA helicase RecQ BG01_2453 ENOG4105EEM helicase BG01_2464 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BG01_2473 ENOG4108M1A Chitin-binding protein BG01_2474 ENOG41082BV acetyltransferase BG01_2475 ENOG4105E66 phosphoriboisomerase A BG01_2480 ENOG4108IJ7 Glycine betaine BG01_2481 ENOG4107SQ8 Glycine betaine BG01_2487 ENOG4105RHY Pfam:UPF0157 BG01_2488 ENOG4105E1F short-chain dehydrogenase reductase BG01_2490 ENOG4107RUY (E1 component), alpha subunit BG01_2492 ENOG4107QKR Dehydrogenase BG01_2497 ENOG41062ES Transcriptional regulator BG01_25 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG01_2501 ENOG4105E98 transcriptional regulator DeoR family BG01_2505 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BG01_2512 ENOG4107Z3H Transcriptional regulator, TetR family BG01_2513 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BG01_2514 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BG01_2515 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BG01_2519 ENOG4105MSI germination protein ypeb BG01_2523 ENOG4108V3A UPF0421 protein BG01_2530 ENOG4105FDR Membrane BG01_2532 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BG01_2541 ENOG4105DY8 decarboxylase BG01_2546 ENOG4105PAD Hydrolase BG01_2551 ENOG4107VFR oxidoreductase BG01_2559 ENOG4105PKS Excinuclease abc c subunit domain protein BG01_2566 ENOG4105KWG Pfam:DUF1696 BG01_2567 ENOG4108NRW Phospholipase, patatin family BG01_257 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG01_2573 ENOG4108XI2 Domain of unknown function (DUF1963) BG01_2580 ENOG4108Z4K mutator MutT protein BG01_2581 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BG01_2582 ENOG4105E09 nadh pyrophosphatase BG01_2584 ENOG4105FCD Major Facilitator BG01_259 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BG01_2591 ENOG4107Y9U Membrane BG01_2596 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BG01_2600 ENOG4107Y80 Major Facilitator superfamily BG01_2605 ENOG4108V4B ThiJ pfpI BG01_261 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BG01_2611 ENOG4105FQP Beta-lactamase BG01_2613 ENOG4105CJN penicillin-binding protein BG01_2614 ENOG4105CB2 alcohol dehydrogenase BG01_2617 ENOG4108HGU Histidine kinase BG01_2620 ENOG4108JJB ABC transporter BG01_2624 ENOG4107RF6 penicillin-binding protein BG01_2625 ENOG4105BZU Histidine kinase BG01_2627 ENOG410667J hydrolase BG01_2650 ENOG4105ETU transcriptional activator (TenA BG01_266 ENOG4105VEQ Cold shock protein BG01_2672 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG01_2673 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG01_2676 ENOG4105CPQ Dehydrogenase BG01_268 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BG01_2683 ENOG4105CUV Homoserine Kinase BG01_2687 ENOG4107Y80 Major Facilitator superfamily BG01_269 ENOG4105E4F Isochorismate synthase BG01_2693 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG01_2693 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG01_27 ENOG4105IW1 AmiS UreI transporter BG01_270 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BG01_2702 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BG01_2704 ENOG4105T9C HD domain BG01_2707 ENOG4105DZ1 carboxypeptidase BG01_271 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BG01_2710 ENOG4105DBI uridine monophosphokinase BG01_2711 ENOG4105WCN acetyltransferase BG01_2713 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BG01_2714 ENOG4107QX3 carboxylase BG01_2715 ENOG4105E39 Enoyl-CoA hydratase BG01_2716 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BG01_2717 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BG01_2718 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BG01_2719 ENOG4105C1G acyl-Coa dehydrogenase BG01_272 ENOG4108IPT Naphthoate synthase BG01_2722 ENOG4107Z3H Transcriptional regulator, TetR family BG01_2724 ENOG4105CJ1 ABC, transporter BG01_2727 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BG01_2728 ENOG4105CEP NADH dehydrogenase BG01_2729 ENOG4106ANW SMI1_KNR4 BG01_2731 ENOG4105BZU Histidine kinase BG01_2733 ENOG4105C5H ABC transporter BG01_2734 ENOG41067SE Tetr family transcriptional regulator BG01_2739 ENOG4108VXD carboxy-peptidase BG01_274 ENOG4105DTQ mandelate racemase muconate lactonizing BG01_2742 ENOG4105VZ8 Transcriptional regulator BG01_2747 ENOG4105CGH 5'-nucleotidase BG01_2751 ENOG4105DH8 myo-inositol catabolism BG01_2752 ENOG4105D2N Aldolase BG01_2758 ENOG4105CK5 oxidoreductase BG01_2759 ENOG4105IE8 Alpha-ketoglutarate permease BG01_2760 ENOG4105ETE Transcriptional regulator (LacI family BG01_2761 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BG01_2763 ENOG4107RF6 penicillin-binding protein BG01_2764 ENOG4107RF6 penicillin-binding protein BG01_2765 ENOG4107RF6 penicillin-binding protein BG01_2771 ENOG4105CIN aminoacyl-histidine dipeptidase BG01_2779 ENOG41090HR transcriptional regulator BG01_2780 ENOG4107RA9 decarboxylase BG01_2781 ENOG4108I0C methyltransferase BG01_2783 ENOG41088CC tellurite resistance protein tehB BG01_2788 ENOG4108RZE Tetr family transcriptional regulator BG01_2790 ENOG4105C1J atp-dependent rna helicase BG01_2793 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BG01_2796 ENOG4107STF Involved in phosphonate degradation (By similarity) BG01_2798 ENOG4105RD7 BadF BadG BcrA BcrD BG01_280 ENOG41069H0 dihydroorotase EC 3.5.2.3 BG01_2803 ENOG4105F32 YngK protein BG01_2808 ENOG4108KPJ rna polymerase sigma factor BG01_2814 ENOG4108JCI Transcriptional regulator BG01_2818 ENOG4105BZ1 (ABC) transporter BG01_2819 ENOG4105BZ1 (ABC) transporter BG01_2822 ENOG4108RPX mosc domain containing protein BG01_2823 ENOG4105DND Transcriptional regulator BG01_2826 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BG01_2827 ENOG4107V2S Transcriptional regulator BG01_2835 ENOG410667J hydrolase BG01_2839 ENOG4105VEQ Cold shock protein BG01_284 ENOG4105FDP GntR family transcriptional regulator BG01_2841 ENOG41068WN BG01_2843 ENOG4105C1Q protoporphyrinogen oxidase BG01_2849 ENOG4105WCN acetyltransferase BG01_285 ENOG4105C6Z Gluconate BG01_2854 ENOG4105EYF MMPL domain protein BG01_2856 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BG01_2859 ENOG41081I9 integral membrane protein BG01_2865 ENOG4108D32 Methyltransferase BG01_2871 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BG01_2875 ENOG4105C22 threonyL-tRNA synthetase BG01_2876 ENOG4105FE9 pseudouridine synthase BG01_2880 ENOG4105BZG amino acid carrier protein BG01_2884 ENOG4105K70 DNA-binding protein BG01_2887 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_2888 ENOG4105WQT MbtH domain protein BG01_2889 ENOG4105CEY Amp-dependent synthetase and ligase BG01_2890 ENOG4105WQI isochorismatase BG01_2891 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BG01_2892 ENOG4105E4F Isochorismate synthase BG01_2893 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BG01_2894 ENOG4105FCD Major Facilitator BG01_2898 ENOG4105EYH Exonuclease BG01_2899 ENOG4107RFY SbcCD D subunit BG01_29 ENOG4105CMR udp-glucose 4-epimerase BG01_2902 ENOG4105E39 Enoyl-CoA hydratase BG01_2903 ENOG4105N14 lysine exporter protein LysE YggA BG01_2905 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG01_2906 ENOG4105C1G acyl-Coa dehydrogenase BG01_2907 ENOG4105CR4 methylisocitrate lyase BG01_2908 ENOG4105DXD 2-methylcitrate dehydratase BG01_2910 ENOG4105W8X HesB YadR YfhF-family protein BG01_2911 ENOG4105CZM Major Facilitator BG01_2921 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG01_2940 ENOG4108IBT Inherit from COG: transposase BG01_2942 ENOG4105SZ6 Thioredoxin BG01_2943 ENOG410841Q phosphoesterase PA-phosphatase related protein BG01_2945 ENOG4108N23 SpoOM-related protein BG01_2953 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BG01_2954 ENOG4108JUB Transcriptional regulator BG01_2955 ENOG4108TSC N-acetyltransferase BG01_2956 ENOG4107S4Y M20 DapE family protein YgeY BG01_2959 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG01_296 ENOG41086D8 Transcriptional regulator BG01_2964 ENOG4105C37 (CBS) domain BG01_297 ENOG4105C19 ABC transporter BG01_2971 ENOG4105E90 ABC transporter BG01_2972 ENOG4108IJ8 ABC transporter BG01_2978 ENOG4105CMG Carbohydrate kinase BG01_2979 ENOG4105CMG Carbohydrate kinase BG01_2987 ENOG4106KNT transcriptional regulator BG01_2989 ENOG4105WH1 Two component transcriptional regulator luxr family BG01_2990 ENOG4105BZU Histidine kinase BG01_2991 ENOG4105D8X mechanosensitive ion channel BG01_2998 ENOG4105F0I Aminotransferase BG01_2999 ENOG4108MES Periplasmic binding protein BG01_3 ENOG4106YBV Methyl-accepting chemotaxis BG01_30 ENOG4108UT2 hemolysin iii BG01_300 ENOG4107ZTW SNARE associated Golgi BG01_3003 ENOG4105CAQ asparagine synthetase BG01_3004 ENOG4107Y70 Heat shock protein BG01_3005 ENOG4108KF3 Electron transport protein SCO1 SenC BG01_3006 ENOG4105E8R UPF0173 metal-dependent hydrolase BG01_3007 ENOG4108RCR degv family BG01_3009 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BG01_3011 ENOG4108UT2 hemolysin iii BG01_3012 ENOG4105E9Q Acyl-transferase BG01_3013 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BG01_3014 ENOG4107RVG penicillin-binding protein BG01_3017 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BG01_3021 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BG01_3026 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BG01_3028 ENOG4105KD7 acetyltransferase BG01_3031 ENOG4105C0A alcohol dehydrogenase BG01_3032 ENOG4105CY2 Citrate transporter BG01_3038 ENOG4105C8J )-transporter BG01_3041 ENOG41062D9 Histidine kinase BG01_3042 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_3043 ENOG4107QPK )-transporter BG01_3044 ENOG4105BZW Glycerate kinase BG01_3063 ENOG4105EC2 ftsk spoIIIe BG01_3067 ENOG4105C5S asparaginyl-tRNA synthetase BG01_3068 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BG01_307 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BG01_3071 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BG01_3077 ENOG4105C75 arginyL-tRNA synthetase BG01_3078 ENOG4107YX5 Pfam:DUF548 BG01_308 ENOG4108UGV hypoxanthine phosphoribosyltransferase BG01_3082 ENOG41061H0 Monooxygenase BG01_3085 ENOG4108UUM single-stranded DNA-binding protein BG01_3088 ENOG4105C5H ABC transporter BG01_3092 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG01_3095 ENOG4105MCT stage V sporulation protein S BG01_3102 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BG01_3103 ENOG4108IFG nitrite reductase, (NAD(P)H) BG01_3104 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BG01_3105 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BG01_3106 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BG01_3107 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BG01_3112 ENOG4108ZAF Molybdopterin BG01_3113 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG01_3114 ENOG4105D06 uba thif-type nad fad binding protein BG01_3115 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BG01_3116 ENOG4107V6Q Cyclic nucleotide-binding domain BG01_3121 ENOG4105R3A Nitrate reductase BG01_3122 ENOG4108IUE nitrate reductase beta subunit BG01_3126 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG01_3129 ENOG4108V06 Glutathione peroxidase BG01_313 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_3134 ENOG4105EMN RNA polymerase sigma factor BG01_3135 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BG01_3137 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_3138 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BG01_314 ENOG4105BZU Histidine kinase BG01_3142 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BG01_3147 ENOG4105KBJ sporulation protein ytfj BG01_3156 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BG01_3162 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BG01_3163 ENOG4108JYZ YitT family BG01_3164 ENOG41087PP glycosyltransferase MGT family BG01_3167 ENOG4107RBS Methyltransferase BG01_3168 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BG01_3170 ENOG4108X4Q Hydrolase BG01_3175 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BG01_3177 ENOG4108VXD carboxy-peptidase BG01_3179 ENOG4108ZRV stage ii sporulation protein p BG01_3182 ENOG4108Z7R Chaperone CsaA BG01_3186 ENOG4105C37 (CBS) domain BG01_3187 ENOG4105SXS Protein of unknown function (DUF456) BG01_3191 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG01_3192 ENOG4108S4H thioesterase Superfamily protein BG01_3194 ENOG4108PJD permease BG01_3197 ENOG4107T5V SNARE associated Golgi BG01_32 ENOG4105C1J atp-dependent rna helicase BG01_3201 ENOG4105CVJ phosphoglycerate mutase BG01_3206 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BG01_3208 ENOG4105K4T epimerase BG01_321 ENOG41087YS Phage shock protein A BG01_3210 ENOG4105DSE periplasmic solute binding protein BG01_3222 ENOG4105CKI cobalamin synthesis protein BG01_3223 ENOG4107QM2 Aldo Keto reductase BG01_3227 ENOG4105DEN Luciferase family BG01_3230 ENOG4108WPJ Ferritin-like domain BG01_3231 ENOG4108K88 Membrane BG01_3234 ENOG4105C8Q Methyl-accepting chemotaxis BG01_3239 ENOG4107XZQ multidrug resistance protein BG01_3240 ENOG4107SET aldo keto reductase BG01_3241 ENOG4105YVS arsR family transcriptional regulator BG01_3243 ENOG4105KRN Transcriptional regulator, abrb family BG01_3254 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BG01_3256 ENOG4107RCC Major Facilitator Superfamily BG01_3258 ENOG4105YWU small acid-soluble spore protein BG01_3259 ENOG4108WBH protein TIM barrel BG01_3262 ENOG4105CEY Amp-dependent synthetase and ligase BG01_3263 ENOG4105DUU IucA IucC family protein BG01_3265 ENOG4105VRR gCN5-related N-acetyltransferase BG01_3266 ENOG4105KT7 mgtC SapB transporter BG01_3268 ENOG4107VMI polysaccharide deacetylase BG01_3269 ENOG4105BZU Histidine kinase BG01_3270 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_3272 ENOG4108KGH TRANSCRIPTIONal BG01_3277 ENOG4105D6E homoserine dehydrogenase BG01_3281 ENOG4108ZJ4 polysaccharide deacetylase BG01_3282 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BG01_3285 ENOG4105BZU Histidine kinase BG01_3286 ENOG4105EFI regulatoR BG01_3287 ENOG4105BZ1 (ABC) transporter BG01_3288 ENOG4105BZ1 (ABC) transporter BG01_3296 ENOG4108JJ8 (ABC) transporter BG01_3297 ENOG4108JJ9 ABC, transporter BG01_3298 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BG01_3299 ENOG4105C4M (Ubiquinol oxidase) subunit I BG01_330 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BG01_3301 ENOG4105YGB Transcriptional regulator BG01_3305 ENOG4105SKE transcriptional Regulator LysR family BG01_3307 ENOG4105C32 Amino acid ABC transporter (Permease) BG01_3308 ENOG4108IV0 ABC, transporter BG01_3309 ENOG4105C0Z ABC transporter BG01_331 ENOG4105C4M (Ubiquinol oxidase) subunit I BG01_3311 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG01_3312 ENOG4108Z7G MaoC domain protein dehydratase BG01_3316 ENOG4105CKI cobalamin synthesis protein BG01_3318 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG01_3319 ENOG4106F5Q Membrane BG01_3320 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BG01_3322 ENOG4108TVJ Nitroreductase BG01_3323 ENOG4107ZXU DSBA oxidoreductase BG01_3324 ENOG4108Z40 Transcriptional regulator BG01_3325 ENOG4105GZI Transcriptional regulator BG01_3326 ENOG4107RT3 EamA-like transporter family BG01_3328 ENOG4105KTB nuclear export factor GLE1 BG01_3329 ENOG4108T5E Copper resistance protein BG01_333 ENOG4108V2W Carbonate dehydratase BG01_3339 ENOG4107STQ Multicopper oxidase BG01_3340 ENOG4107RAQ aminopeptidase BG01_3346 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BG01_3347 ENOG4105D9N nucleoside BG01_3349 ENOG4107RHR regulatoR BG01_3354 ENOG4105C0X amino acid BG01_3355 ENOG4105C0X amino acid BG01_3357 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BG01_3359 ENOG4105C72 UPF0176 protein BG01_3360 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BG01_3364 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_3365 ENOG41068WN BG01_3371 ENOG4108J59 Extracellular solute-binding protein, family 5 BG01_3372 ENOG4105F6J Alpha beta hydrolase fold BG01_3378 ENOG4105DY9 regulatoR BG01_3380 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BG01_3381 ENOG4105C6X Major Facilitator BG01_3386 ENOG4105C7B Threonine dehydratase BG01_3388 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BG01_3389 ENOG4108ZP8 Acetolactate synthase small subunit BG01_3390 ENOG4105C7K acetolactate synthase BG01_3391 ENOG4105CM2 brancheD-chain amino acid aminotransferase BG01_3392 ENOG4105CHR reductase BG01_3393 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BG01_3397 ENOG4106KE4 Dehydrogenase BG01_340 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BG01_3400 ENOG4105H67 Protein of unknown function (DUF421) BG01_3401 ENOG4105X5K response regulator receiver protein BG01_3403 ENOG4105C8J )-transporter BG01_3407 ENOG4105C6T cysteine synthase BG01_3408 ENOG4105EU0 Major facilitator Superfamily BG01_3411 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG01_3414 ENOG4105DXI Major Facilitator superfamily BG01_3415 ENOG4105DXI Major Facilitator superfamily BG01_3416 ENOG4105CSR polyphosphate kinase 2 BG01_3424 ENOG4105FVX BG01_3437 ENOG4105C6K Malic enzyme BG01_3438 ENOG4108IJ0 Aspartate ammonia-lyase BG01_344 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BG01_3440 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BG01_3444 ENOG4105CJ1 ABC, transporter BG01_3451 ENOG4106BRA Membrane BG01_3458 ENOG4107QIV Cytochrome c biogenesis protein BG01_346 ENOG4105D2X ABC transporter substrate-binding protein BG01_3462 ENOG4105EC3 peptidase S51, dipeptidase E BG01_3463 ENOG4107QJQ Mate efflux family protein BG01_3464 ENOG4107QJQ Mate efflux family protein BG01_3468 ENOG4105C9Q fumarate hydratase class II BG01_3469 ENOG4105DFD Na H antiporter BG01_3472 ENOG4108PJD permease BG01_3473 ENOG4105CKI cobalamin synthesis protein BG01_3474 ENOG4108UZ3 Transporter BG01_3475 ENOG4105DRR Transcriptional regulator, GntR family BG01_3477 ENOG4105PGM cation diffusion facilitator family transporter BG01_3481 ENOG4105CAQ asparagine synthetase BG01_3488 ENOG4105CVJ phosphoglycerate mutase BG01_3495 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BG01_3496 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BG01_3497 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG01_3498 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG01_3499 ENOG4105DUM transcriptional regulator, lysR family BG01_35 ENOG4105DPN Oligoendopeptidase f BG01_350 ENOG4107T7U Sulfatase BG01_3504 ENOG4105KAC Antibiotic biosynthesis monooxygenase BG01_3508 ENOG4108RZE Tetr family transcriptional regulator BG01_351 ENOG4107S9D Alpha beta hydrolase BG01_3513 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG01_3514 ENOG4105KTQ flagellar basal-body rod protein BG01_3517 ENOG4105D7B Flagellar biosynthesis protein flha BG01_3518 ENOG4105D00 flagellar biosynthetic protein flhB BG01_352 ENOG4105BZU Histidine kinase BG01_3520 ENOG4105VS8 Flagellar biosynthetic protein fliq BG01_3521 ENOG4105CN7 Flagellar biosynthetic protein FliP BG01_3523 ENOG4105DD5 Flagellar motor switch protein BG01_3525 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BG01_3526 ENOG4105E4C Lytic transglycosylase catalytic BG01_3527 ENOG4105I03 Flagellin BG01_353 ENOG4105BZU Histidine kinase BG01_3532 ENOG4107TVC Glycosyl transferase, family 2 BG01_3538 ENOG4105K64 Glycosyl transferase, family 2 BG01_354 ENOG4105EGD dinuclear metal center protein, YbgI family BG01_3540 ENOG4107R88 Chemotaxis protein (CheV) BG01_3544 ENOG4105BZE flagellar hook protein, FlgE BG01_3551 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BG01_3553 ENOG4107U2N Flagellar M-ring protein BG01_3554 ENOG41075Z6 flagellar hook-basal body complex protein fliE BG01_3555 ENOG4108ZC9 flagellar basal-body rod protein flgc BG01_3556 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BG01_3561 ENOG4105DTJ flagellar hook-associated protein BG01_3562 ENOG4105E1Q flagellar hook-associated protein BG01_3566 ENOG4105BZU Histidine kinase BG01_3569 ENOG4105DD5 Flagellar motor switch protein BG01_3570 ENOG4105CBS Chea signal transduction histidine kinase BG01_3571 ENOG4105CBS Chea signal transduction histidine kinase BG01_3572 ENOG4107YTP response regulator receiver protein BG01_3573 ENOG4105ER2 Ompa motb domain protein BG01_3574 ENOG4107R0U MotA TolQ exbB proton channel BG01_3576 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BG01_3587 ENOG41080C8 DUF218 domain BG01_3588 ENOG4105H67 Protein of unknown function (DUF421) BG01_3592 ENOG4105CN5 Metallo-Beta-Lactamase BG01_3593 ENOG4107RWR Sodium hydrogen exchanger BG01_3595 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG01_3608 ENOG41081VK Ribonuclease BG01_3612 ENOG4108SZE gCN5-related N-acetyltransferase BG01_3630 ENOG4106032 Glutathionylspermidine synthase BG01_3633 ENOG4105KHC sulfurtransferase BG01_3635 ENOG4108W0I acetyltransferase BG01_3637 ENOG410890F Dynamin family BG01_3639 ENOG4105DHF Membrane BG01_364 ENOG4108RIR Molybdenum cofactor biosynthesis protein BG01_3640 ENOG4105C2W permease BG01_3642 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BG01_3645 ENOG4105CTD carboxy-peptidase BG01_3646 ENOG4105DVT helicase BG01_3648 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BG01_3659 ENOG4105BZ4 penicillin-binding protein BG01_366 ENOG4105BZF Glycosyl transferase (Group 1 BG01_3661 ENOG4105CSM endonuclease III BG01_3665 ENOG4105YAC BG01_3666 ENOG4105DVT helicase BG01_367 ENOG4105YVM Phosphoesterase, PA-phosphatase related BG01_3673 ENOG4105CPK Glycosyl transferase (Group 1 BG01_3674 ENOG4105FJR Lmbe family BG01_3677 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BG01_3678 ENOG4108JYZ YitT family BG01_368 ENOG4108Z0R Transferase BG01_3684 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BG01_3685 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BG01_3686 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BG01_3689 ENOG41068YB TPR repeat-containing protein BG01_369 ENOG4105E8V Alpha Beta Hydrolase Fold protein BG01_3690 ENOG4105CIH Imidazole acetol-phosphate transaminase BG01_3694 ENOG4105EAH synthase BG01_3696 ENOG4105XXQ heptaprenyl diphosphate synthase component I BG01_3699 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BG01_3705 ENOG41065D1 BG01_3706 ENOG4105S2F BG01_3713 ENOG4107RB3 L-asparaginase BG01_3714 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BG01_3719 ENOG4108S6Z Negative regulator of genetic competence BG01_3720 ENOG4107X2D transcriptional regulator, merr family BG01_3721 ENOG4107RGJ metallophosphoesterase BG01_3723 ENOG4105I7S Abortive infection protein BG01_3724 ENOG4105C9U ATP-dependent DNA helicase RecQ BG01_3725 ENOG4105T7X BG01_3727 ENOG4108SAX Membrane BG01_3730 ENOG4108WBT adenosyltransferase BG01_3731 ENOG4105BZU Histidine kinase BG01_3732 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_3733 ENOG4105CRE cytochrome C BG01_3734 ENOG4107TWT Cytochrome c biogenesis protein BG01_3736 ENOG4105FE9 pseudouridine synthase BG01_3738 ENOG4108JIC nucleoside recognition domain protein BG01_3739 ENOG4105DZ1 carboxypeptidase BG01_3740 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG01_3747 ENOG4105BZU Histidine kinase BG01_375 ENOG4105DA5 (ABC) transporter BG01_3750 ENOG4105I3N Conserved Protein BG01_3751 ENOG4105BZU Histidine kinase BG01_3754 ENOG4105BZ4 penicillin-binding protein BG01_3755 ENOG4107GRR phosphate transport regulator BG01_3756 ENOG4105CJ3 phosphate transporter BG01_3760 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BG01_3765 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BG01_3769 ENOG4105WH1 Two component transcriptional regulator luxr family BG01_377 ENOG4105N5T Radical SAM Protein BG01_3770 ENOG4105ENE Histidine kinase BG01_3774 ENOG4105DFD Na H antiporter BG01_3778 ENOG4105C8J )-transporter BG01_3779 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BG01_3780 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BG01_3781 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BG01_3783 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BG01_3784 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BG01_3788 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BG01_3790 ENOG4105E0M Sulfatase BG01_3791 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BG01_3794 ENOG4107RVV histidinol phosphate phosphatase, hisj family BG01_3801 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BG01_3806 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BG01_3808 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BG01_3809 ENOG4108ZP8 Acetolactate synthase small subunit BG01_381 ENOG4105C19 ABC transporter BG01_3810 ENOG4105C7K acetolactate synthase BG01_3811 ENOG4105CM2 brancheD-chain amino acid aminotransferase BG01_3816 ENOG4105KBJ sporulation protein ytfj BG01_3817 ENOG41063Y9 BG01_3818 ENOG4105CZN Potassium uptake protein BG01_3824 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG01_3825 ENOG4107QMU Mate efflux family protein BG01_3832 ENOG4105NQC Flavodoxin BG01_3837 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG01_3839 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BG01_384 ENOG4105NCW Trka-c domain protein BG01_3840 ENOG4105EA8 2-Nitropropane dioxygenase BG01_3841 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BG01_3849 ENOG4105CJ1 ABC, transporter BG01_385 ENOG4107S91 Sodium hydrogen exchanger BG01_3851 ENOG4105CZV ABC transporter BG01_3852 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BG01_3853 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG01_3854 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG01_3856 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG01_3857 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BG01_386 ENOG410605W Major Facilitator BG01_3866 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BG01_3867 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BG01_3869 ENOG4105BZU Histidine kinase BG01_3871 ENOG4106DF1 BG01_3873 ENOG41090MY MarR family Transcriptional regulator BG01_3874 ENOG4105BZU Histidine kinase BG01_3876 ENOG4105PXI polysaccharide deacetylase BG01_3878 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BG01_3879 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BG01_3884 ENOG4105E98 transcriptional regulator DeoR family BG01_3887 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BG01_3888 ENOG4107RCV ABC transporter, permease BG01_3891 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG01_3893 ENOG4105C4Y ABC transporter BG01_3897 ENOG4105MWK D-amino acid dehydrogenase, small subunit BG01_3899 ENOG4105CHR reductase BG01_39 ENOG4105C0H protease BG01_3903 ENOG4108Z7G MaoC domain protein dehydratase BG01_3904 ENOG410681C small acid-soluble spore protein BG01_3905 ENOG4105CZN Potassium uptake protein BG01_3906 ENOG4107TS3 membrane protein, TerC BG01_3907 ENOG4108QTI )-transporter BG01_3909 ENOG4106A3R peptidase BG01_3913 ENOG4105JXH GntR family transcriptional regulator BG01_3914 ENOG4105BZU Histidine kinase BG01_3915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_3918 ENOG4105CQB FAD linked oxidase domain protein BG01_3919 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BG01_392 ENOG4108B31 Spore germination protein BG01_3920 ENOG4105K4I Scp-like extracellular BG01_3922 ENOG4108YBP pseudouridine synthase BG01_3924 ENOG4105EYF MMPL domain protein BG01_3926 ENOG4107RUE extracellular solute-binding protein family 1 BG01_3927 ENOG4105D38 putrescine abc transporter BG01_3928 ENOG4105F38 ABC transporter, permease BG01_3929 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG01_3930 ENOG4105C26 Dehydrogenase BG01_3936 ENOG4105VFR signal peptidase BG01_3937 ENOG4105DZ1 carboxypeptidase BG01_3939 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BG01_395 ENOG4105DWV Homoserine O-trans-acetylase BG01_3950 ENOG4105VZ8 Transcriptional regulator BG01_3952 ENOG4105C7S Dehydrogenase BG01_397 ENOG41085GJ domain protein BG01_3970 ENOG4105DDQ anthranilate synthase BG01_3971 ENOG4105CRQ synthase (Component I) BG01_3972 ENOG4105CK7 Sodium proline symporter BG01_3977 ENOG4108WVJ 2'-5' rna ligase BG01_3986 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BG01_3988 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BG01_3989 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BG01_3993 ENOG4107TVC Glycosyl transferase, family 2 BG01_3997 ENOG4105K64 Glycosyl transferase, family 2 BG01_3999 ENOG4105CNI cell division protein FtsW BG01_40 ENOG4105Q2H domain protein BG01_4003 ENOG4105EMS pseudouridine synthase BG01_4004 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BG01_4007 ENOG4105MIX Adenylate cyclase BG01_4008 ENOG4108Z18 K06886 hemoglobin BG01_401 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BG01_4011 ENOG4105DPN Oligoendopeptidase f BG01_4013 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG01_4015 ENOG4108ZCF integral membrane protein BG01_4019 ENOG4105UQX Mate efflux family protein BG01_402 ENOG4105D06 uba thif-type nad fad binding protein BG01_4020 ENOG4108JQ7 (ABC) transporter BG01_4022 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG01_4023 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG01_4026 ENOG4105C31 Tryptophanyl-tRNA synthetase BG01_4029 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BG01_4030 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG01_4035 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BG01_4037 ENOG4108KP7 hydrolase BG01_4039 ENOG41073B9 BG01_404 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG01_4040 ENOG4107AYK membrAne BG01_4042 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG01_4044 ENOG4105QNR S1 RNA binding domain protein BG01_4045 ENOG4105QNR S1 RNA binding domain protein BG01_4049 ENOG4105BZU Histidine kinase BG01_405 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BG01_4050 ENOG4105CH6 catalase BG01_4051 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BG01_4052 ENOG4105CAQ asparagine synthetase BG01_4057 ENOG4105ERH Fumarylacetoacetate hydrolase BG01_406 ENOG4108ZAF Molybdopterin BG01_4065 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BG01_4066 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BG01_4069 ENOG4105XVF Competence transcription factor BG01_4072 ENOG4105VEQ Cold shock protein BG01_4075 ENOG4107QP3 malate synthase g BG01_4076 ENOG4105ZU5 s-layer protein BG01_4080 ENOG4105C8Q Methyl-accepting chemotaxis BG01_4081 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BG01_4086 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_409 ENOG4105CSC Glucose uptake protein BG01_4090 ENOG41086D8 Transcriptional regulator BG01_4091 ENOG4108AEY RNA polymerase sigma factor BG01_4093 ENOG4107TVP HD domain protein BG01_4094 ENOG4107RN3 metallophosphoesterase BG01_4096 ENOG4105ENX hydrolase BG01_410 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BG01_4101 ENOG4105CNA YD repeat protein BG01_4107 ENOG4105CEY Amp-dependent synthetase and ligase BG01_4109 ENOG4105DF9 Lipoate-protein, ligase BG01_411 ENOG4108VJ1 Transcriptional regulator (CarD family BG01_4110 ENOG4108RQ5 Beta-lactamase domain-containing protein BG01_4111 ENOG4106AXD BG01_4117 ENOG4105ECB domain protein BG01_4120 ENOG4105NA0 Transcriptional regulator BG01_4125 ENOG4105C1Q protoporphyrinogen oxidase BG01_4127 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BG01_4128 ENOG4105BZ4 penicillin-binding protein BG01_4129 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BG01_4130 ENOG4105CKV Membrane BG01_4131 ENOG410905X membrane-flanked domain protein BG01_4140 ENOG4105CKV Membrane BG01_4142 ENOG410905X membrane-flanked domain protein BG01_4149 ENOG4105K59 histidine triad (HIT) protein BG01_4154 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG01_4155 ENOG4105EEM helicase BG01_4157 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_4158 ENOG4105C57 major facilitator superfamily BG01_4163 ENOG4105EMN RNA polymerase sigma factor BG01_4166 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BG01_4169 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BG01_4173 ENOG4108MUZ hydrolase BG01_4178 ENOG4105EQ0 Major Facilitator superfamily BG01_4179 ENOG4108IND Tetr family transcriptional regulator BG01_418 ENOG4105CBX hi0933 family BG01_4182 ENOG4105D7V transposase BG01_4183 ENOG4106D4I domain protein BG01_4184 ENOG4107VRP DNA repair exonuclease BG01_4190 ENOG4105K8R UPF0145 protein BG01_4195 ENOG4105BZU Histidine kinase BG01_4196 ENOG4105BZU Histidine kinase BG01_4197 ENOG4108MJI response regulator BG01_4199 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_4201 ENOG4105WN5 stage II sporulation protein BG01_421 ENOG4105YW5 deoR family transcriptional regulator BG01_4214 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BG01_4219 ENOG410847I Transcriptional regulator, BadM Rrf2 family BG01_422 ENOG4107QSE Dipeptidase BG01_4220 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BG01_4221 ENOG4105CMT Dihydroxyacetone kinase BG01_4223 ENOG4105CMT Dihydroxyacetone kinase BG01_4227 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BG01_423 ENOG4107QSE Dipeptidase BG01_4231 ENOG4108IG5 Transcriptional regulator BG01_4232 ENOG4107P5I polyketide synthase BG01_4242 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_425 ENOG4108IUM Glycogen debranching enzyme BG01_4250 ENOG4105CDU Replicative dna helicase BG01_4259 ENOG4108MRH transcriptional regulatory protein BG01_426 ENOG4108V15 phosphotransferase enzyme family BG01_4261 ENOG4105CSH Transporter BG01_4267 ENOG4108JQ7 (ABC) transporter BG01_4270 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG01_4278 ENOG4105CTU Proline racemase BG01_4283 ENOG4105DER m42 family BG01_4286 ENOG4105CGU Enoyl-CoA hydratase BG01_4289 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG01_429 ENOG4105C8F Beta-lactamase domain protein BG01_4290 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG01_4292 ENOG4106AKK s-layer domain-containing protein BG01_43 ENOG4105BZU Histidine kinase BG01_4300 ENOG4105CHH sulfate transporter BG01_4303 ENOG4105D4P Coproporphyrinogen iii oxidase BG01_4305 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG01_4310 ENOG4107FQX Alpha-acetolactate decarboxylase BG01_4317 ENOG410839P BG01_4320 ENOG4105CDA abc transporter atp-binding protein BG01_4321 ENOG4105DRP amino acid AbC transporter BG01_4323 ENOG4105BZ1 (ABC) transporter BG01_4324 ENOG4105BZ1 (ABC) transporter BG01_4325 ENOG4105BZ1 (ABC) transporter BG01_4326 ENOG4105C26 Dehydrogenase BG01_4328 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BG01_4329 ENOG4105D5Q Arginine ornithine antiporter BG01_4331 ENOG4105CH6 catalase BG01_4332 ENOG4107RKG DJ-1/PfpI family BG01_4334 ENOG4105E5W Transporter BG01_4335 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BG01_4336 ENOG4105NF4 modulator of drug activity BG01_4341 ENOG4105KPY Small multidrug resistance protein BG01_4342 ENOG4105KPY Small multidrug resistance protein BG01_4344 ENOG4108YXU transcriptional regulator AsnC family BG01_4345 ENOG4108PCN EamA-like transporter family BG01_435 ENOG4108VDD TRNA binding domain protein BG01_4352 ENOG4106KNT transcriptional regulator BG01_4354 ENOG4107RWR Sodium hydrogen exchanger BG01_4355 ENOG4105CUB amino acid BG01_4361 ENOG4107T5V SNARE associated Golgi BG01_4368 ENOG4105WEF catalase BG01_4374 ENOG4105C19 ABC transporter BG01_4375 ENOG4107RBB ABC transporter, permease BG01_4376 ENOG41069ER domain protein BG01_4380 ENOG4105VZJ PTS System BG01_4381 ENOG4105VCP PTS System BG01_4382 ENOG4105EMD TRANSCRIPTIONal BG01_4387 ENOG4108KGH TRANSCRIPTIONal BG01_4389 ENOG41087NI Sulfite exporter TauE/SafE BG01_4390 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BG01_4392 ENOG41085GJ domain protein BG01_4394 ENOG4105VFE sira family BG01_4395 ENOG4107TPS domain protein BG01_4396 ENOG4105VFE sira family BG01_4397 ENOG4105XTG Pfam:DUF156 BG01_4398 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BG01_44 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_4403 ENOG4105ED1 spovr family BG01_4404 ENOG4107Y03 Nitroreductase BG01_4409 ENOG4108B31 Spore germination protein BG01_4416 ENOG4105C5Y PTS System BG01_4423 ENOG4105C7N Xanthine uracil vitamin C permease BG01_4426 ENOG4108INS Transcriptional regulator BG01_4435 ENOG4105DWF phosphomethylpyrimidine kinase BG01_4436 ENOG4105D06 uba thif-type nad fad binding protein BG01_4439 ENOG41080HI glycine oxidase BG01_444 ENOG4105C88 aminopeptidase BG01_4440 ENOG4108VEU Thiamine monophosphate synthase BG01_4442 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BG01_4444 ENOG4105ETU transcriptional activator (TenA BG01_4448 ENOG41080XQ Signal transduction protein with cbs domains BG01_4475 ENOG4105E2Z phosphate ABC transporter (Permease BG01_4476 ENOG4105C8U phosphate abc transporter BG01_4477 ENOG4105CVA phosphate BG01_4478 ENOG4105CE1 Ferrous iron transport protein b BG01_4479 ENOG4105CE1 Ferrous iron transport protein b BG01_448 ENOG4105ETE Transcriptional regulator (LacI family BG01_4480 ENOG4105CE1 Ferrous iron transport protein b BG01_4481 ENOG4108NHD germination protein BG01_4484 ENOG4105E1V na solute symporter BG01_4485 ENOG4106CAD Protein of unknown function (DUF3311) BG01_4488 ENOG4105E2S oxidase) subunit II BG01_4489 ENOG4105BZ9 Cytochrome C oxidase, subunit I BG01_4497 ENOG4105C7N Xanthine uracil vitamin C permease BG01_4498 ENOG4105C85 amino acid BG01_4502 ENOG4105DUX Transporter BG01_4504 ENOG4107D63 BG01_4505 ENOG4105VZ8 Transcriptional regulator BG01_4506 ENOG41069ER domain protein BG01_4507 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BG01_4508 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG01_4520 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BG01_4521 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BG01_4522 ENOG4105CNN ABC, transporter BG01_4523 ENOG4105C2J ABC transporter BG01_4525 ENOG4108RVA ribokinase BG01_4526 ENOG4105ETE Transcriptional regulator (LacI family BG01_4527 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_4528 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_4529 ENOG41067TZ transcriptional regulator, MarR family BG01_4530 ENOG4105CXY transporter BG01_4532 ENOG4108JQ7 (ABC) transporter BG01_4533 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG01_4535 ENOG4105DEF Extracellular solute-binding protein, family 5 BG01_4537 ENOG41068KF Universal stress protein BG01_4538 ENOG4105CHH sulfate transporter BG01_454 ENOG4105EP9 oxidoreductase BG01_4541 ENOG4105BZU Histidine kinase BG01_4542 ENOG4105NAE bifunctional deaminase-reductase domain protein BG01_4543 ENOG4105D29 Helix-turn-helix type 11 domain protein BG01_4548 ENOG4108IQI permease BG01_4549 ENOG4105DRP amino acid AbC transporter BG01_455 ENOG4107SNB ankyrin repeat protein YahD BG01_4550 ENOG4105EAD ABC transporter BG01_4551 ENOG4105CT1 (ABC) transporter BG01_4552 ENOG4105CDA abc transporter atp-binding protein BG01_4553 ENOG4105BZG amino acid carrier protein BG01_4554 ENOG4105CRN Aminoglycoside phosphotransferase BG01_4556 ENOG4105E1K spore germination protein BG01_4559 ENOG4105CG3 alpha amylase, catalytic region BG01_4560 ENOG4105C5Y PTS System BG01_4561 ENOG4107414 GntR family transcriptional regulator BG01_4562 ENOG4105D5Q Arginine ornithine antiporter BG01_4563 ENOG4105BZU Histidine kinase BG01_4566 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG01_4567 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BG01_4568 ENOG4107T89 von Willebrand factor, type A BG01_457 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_4570 ENOG4105EXW epimerase dehydratase BG01_4572 ENOG4105DMQ Methyltransferase BG01_4573 ENOG4105E0A ABC, transporter BG01_4574 ENOG4108IHU transport system permease protein BG01_4575 ENOG4105DQ5 transport system permease protein BG01_4576 ENOG4108MES Periplasmic binding protein BG01_4577 ENOG4105DUX Transporter BG01_4580 ENOG4105DAA L-lactate BG01_4581 ENOG4108IJ0 Aspartate ammonia-lyase BG01_4582 ENOG4105C37 (CBS) domain BG01_4583 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BG01_4584 ENOG4105D9N nucleoside BG01_4585 ENOG4108KGH TRANSCRIPTIONal BG01_4586 ENOG41073R8 VanW family BG01_459 ENOG4105DGU Histone deacetylase BG01_4593 ENOG4105DAP Nicotinate phosphoribosyltransferase BG01_4594 ENOG4105C59 p-type ATPase BG01_4596 ENOG4105CUB amino acid BG01_460 ENOG4105W87 Cbs domain BG01_4601 ENOG4108JB9 formate dehydrogenase BG01_4602 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BG01_4603 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BG01_4605 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_4606 ENOG4105BZU Histidine kinase BG01_4608 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BG01_4609 ENOG4108UZ3 Transporter BG01_461 ENOG4105F1V Acetoin utilization protein BG01_4611 ENOG4105C6K Malic enzyme BG01_4613 ENOG4108MRH transcriptional regulatory protein BG01_4618 ENOG4105US7 Histidine kinase BG01_4619 ENOG4108STX response regulator BG01_4620 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BG01_4621 ENOG4105BZ7 extracellular solute-binding protein family 1 BG01_4622 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BG01_4623 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BG01_4624 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG01_4625 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BG01_4629 ENOG4105D4T Citrate transporter BG01_4632 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BG01_4634 ENOG4105DZ6 Band 7 protein BG01_4637 ENOG4105C94 Transporter BG01_464 ENOG4105EMN RNA polymerase sigma factor BG01_4641 ENOG4105CYN Serine protein kinase BG01_4643 ENOG4105BZU Histidine kinase BG01_4644 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BG01_4646 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BG01_4648 ENOG4107ZQN disulfide bond BG01_4649 ENOG4108JQC penicillin-binding protein 1A BG01_466 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BG01_4676 ENOG4105G5W regulator Fur family BG01_4677 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BG01_4681 ENOG4108IUW ABC transporter BG01_4683 ENOG4105CBC glutamate synthase BG01_4684 ENOG4107NBY Membrane BG01_4685 ENOG4105BZ1 (ABC) transporter BG01_4689 ENOG4106BXE BG01_4690 ENOG4105CEN a g-specific adenine glycosylase BG01_4691 ENOG41067AE Membrane-bound metal-dependent hydrolase BG01_4697 ENOG4105ECP epimerase BG01_4698 ENOG4105CI2 imidazolone-5-propionate hydrolase BG01_470 ENOG4105C28 cystathionine BG01_4702 ENOG4105F1A Pyruvate formate-lyase BG01_4705 ENOG4105C3I Nad-dependent epimerase dehydratase BG01_4706 ENOG4107QQG Dehydrogenase BG01_4708 ENOG4105CKK Glycosyl transferase, family 2 BG01_4711 ENOG4108A04 Beta-lactamase BG01_4713 ENOG4105CSV Glutaminase BG01_4719 ENOG4108IQI permease BG01_472 ENOG4105U5Y Transcriptional regulator BG01_4721 ENOG4108JUB Transcriptional regulator BG01_4723 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BG01_473 ENOG4105U5Y Transcriptional regulator BG01_475 ENOG4106KR7 LysR family Transcriptional regulator BG01_4781 ENOG4105VTR Integrase BG01_4782 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BG01_4790 ENOG4105UPD Calcium Proton BG01_4791 ENOG410606W general stress protein BG01_4794 ENOG4107ZTW SNARE associated Golgi BG01_4797 ENOG4105C3F Signal peptidase i BG01_4799 ENOG4108IPJ Membrane BG01_4800 ENOG4105C59 p-type ATPase BG01_4801 ENOG4107U9T Pfam:Ribonuclease_BN BG01_4803 ENOG4105KJF protein tyrosine phosphatase BG01_4807 ENOG4108TTB tellurium resistance protein BG01_4808 ENOG4107TS3 membrane protein, TerC BG01_4809 ENOG4106FN3 tellurium resistance protein BG01_4810 ENOG4106FN3 tellurium resistance protein BG01_4811 ENOG4108N0M stress protein BG01_4814 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BG01_4817 ENOG4105DEU major facilitator superfamily BG01_4821 ENOG41062JF Transcriptional regulator BG01_4826 ENOG4105C5H ABC transporter BG01_4829 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BG01_483 ENOG4105EFZ amidohydrolase BG01_4832 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BG01_4838 ENOG4105CI1 PTS System BG01_4840 ENOG4105C8Q Methyl-accepting chemotaxis BG01_4841 ENOG4105C8Q Methyl-accepting chemotaxis BG01_4843 ENOG4105EAB amino acid AbC transporter BG01_4844 ENOG4105E5Q amino acid AbC transporter BG01_4847 ENOG4105D2S major facilitator superfamily BG01_4848 ENOG410756H nucleotidyltransferase BG01_4852 ENOG4105BZU Histidine kinase BG01_4856 ENOG4106UIA BG01_4857 ENOG4106UIA BG01_486 ENOG4105KBJ sporulation protein ytfj BG01_4861 ENOG4108V5C ABC transporter BG01_4862 ENOG4105DQ5 transport system permease protein BG01_4863 ENOG4105EHG Permease protein BG01_4864 ENOG4107W7X Aldolase BG01_4866 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BG01_4867 ENOG4105D3R alkyl hydroperoxide reductase BG01_487 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BG01_4872 ENOG4105DFD Na H antiporter BG01_4873 ENOG4105DTQ mandelate racemase muconate lactonizing BG01_4876 ENOG4108W15 Protein of unknown function (DUF1456) BG01_4879 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BG01_4880 ENOG4105D9N nucleoside BG01_4884 ENOG4105KPY Small multidrug resistance protein BG01_4885 ENOG4105C26 Dehydrogenase BG01_4887 ENOG4108JPW Aminotransferase BG01_4888 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BG01_4889 ENOG4105CBD Diacylglycerol kinase BG01_489 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BG01_4894 ENOG410834F Transcriptional regulator BG01_4895 ENOG4105D0U Arsenite-activated ATPase (ArsA) BG01_4899 ENOG4105D01 (LipO)protein BG01_4900 ENOG4108UMI ABC transporter, permease BG01_4901 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG01_4902 ENOG4108W2Y isochorismatase BG01_4908 ENOG4105C4R Atp-dependent dna helicase BG01_4913 ENOG4105C12 Phosphoribosylglycinamide synthetase BG01_4915 ENOG4108V3E phosphoribosylglycinamide formyltransferase BG01_4920 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BG01_4922 ENOG4105C83 adenylosuccinate lyase BG01_4923 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BG01_4924 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BG01_4929 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_493 ENOG4108JYZ YitT family BG01_4933 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG01_4938 ENOG4105BZU Histidine kinase BG01_4940 ENOG4105C7N Xanthine uracil vitamin C permease BG01_4944 ENOG4108TYN CAAX amino terminal protease family protein BG01_4947 ENOG4105C5H ABC transporter BG01_4948 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BG01_4949 ENOG410801F ribosomal-protein-alanine acetyltransferase BG01_4950 ENOG41072GX Peptidase M22 Glycoprotease BG01_4951 ENOG4105K8N protein family UPF0079, ATPase BG01_4971 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BG01_4973 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BG01_4974 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BG01_4977 ENOG4107ZXI Rhomboid family BG01_4979 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BG01_4980 ENOG4105CPF Cell wall formation (By similarity) BG01_4981 ENOG4105CPF Cell wall formation (By similarity) BG01_4982 ENOG4108SC4 )-transporter BG01_4984 ENOG4105ERH Fumarylacetoacetate hydrolase BG01_4985 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BG01_4989 ENOG4108JQ7 (ABC) transporter BG01_4990 ENOG410667J hydrolase BG01_4991 ENOG4105C3U ABC transporter BG01_4992 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG01_4994 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BG01_4997 ENOG4105C5H ABC transporter BG01_5 ENOG4108S4H thioesterase Superfamily protein BG01_50 ENOG4105CDU Replicative dna helicase BG01_5001 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BG01_5002 ENOG4108RE7 deoxyribonuclease BG01_5005 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BG01_5009 ENOG4105F6E Acyl-transferase BG01_5013 ENOG4105EGI Transcriptional regulator BG01_5016 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BG01_5017 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG01_5018 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG01_5019 ENOG4105E0C molybdate abc transporter BG01_502 ENOG4107YZX Universal stress protein BG01_5021 ENOG4107XDY Nicotinamide Mononucleotide Transporter BG01_5022 ENOG4105II7 pyrroline-5-carboxylate reductase BG01_5024 ENOG4108J59 Extracellular solute-binding protein, family 5 BG01_5025 ENOG4108J59 Extracellular solute-binding protein, family 5 BG01_5031 ENOG4108JQ7 (ABC) transporter BG01_5032 ENOG4105C3U ABC transporter BG01_5033 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG01_5034 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG01_5037 ENOG4105C2C drug resistance transporter, Bcr CflA BG01_5040 ENOG4105IQ5 FAD linked oxidase domain protein BG01_5042 ENOG4105EE1 crotonyl-CoA reductase BG01_5043 ENOG4105D01 (LipO)protein BG01_5044 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG01_5045 ENOG4108UMI ABC transporter, permease BG01_5046 ENOG4108PSK reductase BG01_5054 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BG01_5055 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BG01_5057 ENOG4105CMG Carbohydrate kinase BG01_5058 ENOG4105CMG Carbohydrate kinase BG01_506 ENOG4105VZ8 Transcriptional regulator BG01_5060 ENOG4108VQT Alpha beta hydrolase fold protein BG01_5061 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BG01_5063 ENOG4107U5W ybbr family BG01_5064 ENOG4105C8B TIGR00159 family BG01_508 ENOG41082W1 Cupin 2, conserved barrel domain protein BG01_5081 ENOG4105KT7 mgtC SapB transporter BG01_5083 ENOG4107PBV potassium channel BG01_5084 ENOG4107QYV phosphohexose isomerase BG01_5085 ENOG4105WG9 Conserved Protein BG01_5087 ENOG4105CHM Aminotransferase BG01_5088 ENOG4108ZB6 transcriptional regulator AsnC family BG01_5089 ENOG4105C5I Dehydrogenase BG01_509 ENOG4105Z7P Acetyltransferase (GNAT) family BG01_5090 ENOG4108MUZ hydrolase BG01_5092 ENOG4105C87 Aminotransferase class I and II BG01_5095 ENOG4105Y38 Kinase-associated protein B BG01_5097 ENOG4107R3E Citrate transporter BG01_5100 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BG01_5101 ENOG4105KA0 thioesterase Superfamily protein BG01_5105 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BG01_5109 ENOG41069ER domain protein BG01_5112 ENOG4105CEP NADH dehydrogenase BG01_5118 ENOG4105EWC Purine nucleoside phosphorylase BG01_5121 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BG01_5125 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG01_5126 ENOG4105C4B ABC transporter, permease BG01_5127 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BG01_5136 ENOG41083MR nifu domain-containing protein BG01_5139 ENOG4108W5N phosphatidylglycerophosphatase a BG01_5141 ENOG4105DYS nad(p)h dehydrogenase (quinone) BG01_5142 ENOG4105D4U had-superfamily hydrolase, subfamily iia BG01_5145 ENOG4105CBT Fructose-1,6-bisphosphatase BG01_5148 ENOG4105MMD transcriptional regulator BG01_5149 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BG01_5150 ENOG4107TXC Transcriptional regulator BG01_5151 ENOG41090T1 Membrane BG01_5156 ENOG4105FAA peptidase M23 BG01_5158 ENOG4105KZD Domain of unknown function (DUF1805) BG01_5159 ENOG4107R8B 5'-nucleotidase BG01_516 ENOG4105DC7 peptidase M24 BG01_5162 ENOG4105DIW FeS assembly protein SUFB BG01_5163 ENOG4108UNV SUF system FeS assembly protein, NifU family BG01_5164 ENOG4105C9B Cysteine desulfurase BG01_5165 ENOG4105JRK feS assembly protein SufD BG01_5166 ENOG4105C3K feS assembly ATPase SufC BG01_5167 ENOG4105D01 (LipO)protein BG01_5168 ENOG4105D01 (LipO)protein BG01_5169 ENOG4108UMI ABC transporter, permease BG01_5175 ENOG41080E8 Transcriptional regulator, Spx MgsR family BG01_5184 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG01_5190 ENOG4108W8B Beta-lactamase domain protein BG01_5191 ENOG4105C1G acyl-Coa dehydrogenase BG01_5192 ENOG4105CHU acetyl-coa acetyltransferase BG01_5195 ENOG4105DZ1 carboxypeptidase BG01_5199 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BG01_52 ENOG4105BZR domain protein BG01_5203 ENOG4108SUT Major Facilitator Superfamily BG01_5204 ENOG4107R7I amino acid BG01_5206 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BG01_5208 ENOG4107AYK membrAne BG01_5215 ENOG4107ZTW SNARE associated Golgi BG01_5217 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BG01_5218 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_5219 ENOG4105BZU Histidine kinase BG01_5221 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BG01_5224 ENOG4105VG1 fes assembly suf system protein BG01_5225 ENOG4105D4Y metalloprotease BG01_5229 ENOG4107S91 Sodium hydrogen exchanger BG01_523 ENOG4105SFS phosphoesterase RecJ domain protein BG01_5230 ENOG4105NCW Trka-c domain protein BG01_5232 ENOG4108RMU ferritin dps family protein BG01_5235 ENOG4108URH decarboxylase BG01_5240 ENOG4105D9N nucleoside BG01_5241 ENOG4105D9N nucleoside BG01_5244 ENOG4108RYK Nad-dependent epimerase dehydratase BG01_5249 ENOG4105CV8 reductase BG01_525 ENOG4105VV2 BG01_5250 ENOG4105F27 Major Facilitator BG01_5251 ENOG4105KVH Transcriptional regulator BG01_5254 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BG01_5255 ENOG4105D4A Cell wall formation (By similarity) BG01_5257 ENOG4105C8Q Methyl-accepting chemotaxis BG01_5259 ENOG4105WMR Protein CrcB homolog BG01_526 ENOG4105C0B DNA polymerase III (alpha subunit) BG01_5260 ENOG4105WMR Protein CrcB homolog BG01_5263 ENOG4108MK9 spermidine N(1)-acetyltransferase BG01_5264 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BG01_5267 ENOG4108IPW abc transporter atp-binding protein BG01_5268 ENOG4105CM4 permease protein BG01_527 ENOG4105C6K Malic enzyme BG01_5273 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BG01_5275 ENOG4105XZU Preprotein translocase, subunit SecG BG01_5276 ENOG41067MG lrgb family BG01_528 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BG01_5295 ENOG4105EFC phage portal protein HK97 family BG01_53 ENOG4108XMW Membrane BG01_5300 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG01_5302 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BG01_5303 ENOG4105CP7 Triose-phosphate isomerase BG01_5308 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_5312 ENOG41090VF Stage v sporulation protein ac BG01_5313 ENOG4105CZ3 stage V sporulation protein ad BG01_5316 ENOG4105H67 Protein of unknown function (DUF421) BG01_5317 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BG01_5318 ENOG4105KRI phosphocarrier protein (HPr BG01_5320 ENOG4105CHW UPF0052 protein BG01_5322 ENOG4108Z4K mutator MutT protein BG01_5324 ENOG4105C3M thioredoxin reductase BG01_5326 ENOG4108S4C acetyltransferase BG01_533 ENOG4105FS0 cytoplasmic membrane protein BG01_5330 ENOG41086DT Membrane protein of unknown function BG01_5332 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG01_5333 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BG01_5334 ENOG4105D7V transposase BG01_5337 ENOG4107TXC Transcriptional regulator BG01_534 ENOG4108REF Sporulation integral membrane protein ytvi BG01_5341 ENOG4105HMI Membrane BG01_5342 ENOG4105DUM transcriptional regulator, lysR family BG01_5344 ENOG4108WS4 fmn reductase BG01_5347 ENOG4105BZ1 (ABC) transporter BG01_5349 ENOG4105CN1 protease BG01_5350 ENOG4105CRP Part of the ABC transporter FtsEX involved in BG01_5351 ENOG4105CAK Cell division ATP-binding protein ftsE BG01_5353 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BG01_5354 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BG01_5355 ENOG4105MS2 ribosomal subunit Interface protein BG01_5356 ENOG4105VEQ Cold shock protein BG01_5357 ENOG41081UC Inherit from COG: Competence protein BG01_536 ENOG4105BZN citrate synthase BG01_5360 ENOG4105KVH Transcriptional regulator BG01_5362 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BG01_5363 ENOG4108KGH TRANSCRIPTIONal BG01_5364 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BG01_5365 ENOG4105C6Y Udp-glucose 6-dehydrogenase BG01_5366 ENOG4105ESV Glycosyl transferase, family 4 BG01_5368 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BG01_537 ENOG4108HMX isocitrate dehydrogenase (NADP) BG01_5371 ENOG410901P UPF0249 protein BG01_5372 ENOG4105F8D glycoside hydrolase family 4 BG01_5373 ENOG4105VCP PTS System BG01_5374 ENOG4105CK1 PTS System BG01_5376 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BG01_5377 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BG01_5378 ENOG4105VCP PTS System BG01_5380 ENOG4105VZJ PTS System BG01_5383 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_5384 ENOG4105ECB domain protein BG01_5385 ENOG4107RSM transcriptional regulator BG01_5393 ENOG4105DAA L-lactate BG01_5395 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BG01_5397 ENOG4105E0M Sulfatase BG01_5406 ENOG4105C94 Transporter BG01_5407 ENOG41069ER domain protein BG01_541 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_5412 ENOG4105KBK Zinc finger, swim domain protein BG01_5413 ENOG4105C0D helicase BG01_5419 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_542 ENOG4105BZU Histidine kinase BG01_5421 ENOG4107RBB ABC transporter, permease BG01_5422 ENOG4105C19 ABC transporter BG01_5426 ENOG4105CXY transporter BG01_5429 ENOG4105BZU Histidine kinase BG01_543 ENOG4105C2M dna polymerase I BG01_5430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG01_5431 ENOG4105CMR udp-glucose 4-epimerase BG01_5434 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BG01_5435 ENOG4105EY8 ABC transporter BG01_544 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BG01_5446 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BG01_5448 ENOG4105FRN stage II sporulation protein BG01_5451 ENOG4105DY9 regulatoR BG01_5452 ENOG4108IUW ABC transporter BG01_5456 ENOG4106778 Protein of unknown function (DUF1146) BG01_5457 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BG01_5458 ENOG4105C8S subunit m BG01_5459 ENOG4105D65 subunit l BG01_546 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BG01_5464 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BG01_5465 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BG01_5467 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BG01_5468 ENOG4105BZU Histidine kinase BG01_547 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BG01_5478 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BG01_5479 ENOG41062M3 atp synthase BG01_548 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BG01_5484 ENOG4108YZG isomerase BG01_5487 ENOG4108VGI doxx family BG01_5488 ENOG4107XC4 flavin reductase domain protein, FMN-binding BG01_5491 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BG01_5493 ENOG4108ZXQ stage ii sporulation protein r BG01_5494 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BG01_5495 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BG01_5498 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BG01_5499 ENOG4105CBT Fructose-1,6-bisphosphatase BG01_55 ENOG4108UUM single-stranded DNA-binding protein BG01_5500 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BG01_5507 ENOG4105C1G acyl-Coa dehydrogenase BG01_5508 ENOG4105C1G acyl-Coa dehydrogenase BG01_5509 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BG01_5511 ENOG4105DF6 Fe-S oxidoreductase BG01_5514 ENOG4105BZU Histidine kinase BG01_5519 ENOG4105BZU Histidine kinase BG01_552 ENOG4108TDW sporulation protein YtxC BG01_5521 ENOG4105KCT ABC transporter BG01_5522 ENOG4108M15 ABC transporter BG01_5523 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BG01_5527 ENOG4105IIU Aminopeptidase BG01_553 ENOG4105C22 threonyL-tRNA synthetase BG01_5531 ENOG4105EMN RNA polymerase sigma factor BG01_5533 ENOG410684U Domain of unknown function (DUF1934) BG01_5537 ENOG4105CYW agmatinase BG01_5539 ENOG4105DXB Major Facilitator superfamily BG01_554 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BG01_5540 ENOG4107SWG transcriptional regulator MERR family BG01_5541 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BG01_5542 ENOG4105BZ4 penicillin-binding protein BG01_5543 ENOG4108XFG YwhD family BG01_5544 ENOG4108Z4T Peptidase M50 BG01_5545 ENOG41069HH 4-oxalocrotonate tautomerase BG01_5546 ENOG4105DCI Phosphohydrolase BG01_5547 ENOG4108MES Periplasmic binding protein BG01_5548 ENOG4105E0A ABC, transporter BG01_5549 ENOG4105EHG Permease protein BG01_5550 ENOG4105DQ5 transport system permease protein BG01_5551 ENOG4105DQ5 transport system permease protein BG01_5553 ENOG4108VCI transcription factor, rsfa family BG01_5556 ENOG4108IJ2 phosphate acetyltransferase BG01_5559 ENOG4108VKI Cell wall hydrolase BG01_5563 ENOG4107SVH Potassium channel protein BG01_5565 ENOG410667J hydrolase BG01_5566 ENOG4105VCH membrane BG01_5568 ENOG4108TU7 Inherit from COG: (ABC) transporter BG01_5569 ENOG4105CJ1 ABC, transporter BG01_5570 ENOG41090WU lipolytic protein G-D-S-L family BG01_5573 ENOG4105D6E homoserine dehydrogenase BG01_5578 ENOG4108Y4K DNA-binding transcriptional activator BG01_558 ENOG4105CN9 Peptidase m42 family protein BG01_5580 ENOG4105WH1 Two component transcriptional regulator luxr family BG01_5581 ENOG4105BZU Histidine kinase BG01_5582 ENOG4105BZU Histidine kinase BG01_5583 ENOG4105DWF phosphomethylpyrimidine kinase BG01_5584 ENOG4105BZU Histidine kinase BG01_5585 ENOG4105VCD cytoplasmic protein BG01_5586 ENOG4105D22 carbon starvation protein BG01_5587 ENOG4105DY9 regulatoR BG01_5588 ENOG41079KZ Major Facilitator Superfamily BG01_559 ENOG4108JGH Tetr family transcriptional regulator BG01_5599 ENOG4105DHF Membrane BG01_560 ENOG4105CW7 secretion protein, HlyD family BG01_5605 ENOG4106AKK s-layer domain-containing protein BG01_5606 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BG01_561 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG01_5610 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BG01_5611 ENOG4105C6Y Udp-glucose 6-dehydrogenase BG01_5614 ENOG4105DQ6 Transposase BG01_5648 ENOG4105KRN Transcriptional regulator, abrb family BG01_5651 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG01_5658 ENOG4108IBT Inherit from COG: transposase BG01_5665 ENOG4105DQ6 Transposase BG01_5666 ENOG4105DQ6 Transposase BG01_5668 ENOG4108MEK Metal-binding protein YodA BG01_5670 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BG01_5677 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BG01_5698 ENOG4105EKQ RNA-directed DNA polymerase BG01_57 ENOG4105C3G gtp-binding protein BG01_571 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BG01_5719 ENOG4105EKQ RNA-directed DNA polymerase BG01_572 ENOG4105C5S asparaginyl-tRNA synthetase BG01_5731 ENOG4106JUT Streptomycin 3''-adenylyltransferase BG01_5744 ENOG4105CNU cell division protein FtsK BG01_579 ENOG4105DCG PHP domain protein BG01_58 ENOG4105VDK protein, conserved in bacteria BG01_582 ENOG4105FE9 pseudouridine synthase BG01_5820 ENOG4105K4H Nlp p60 protein BG01_5834 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG01_5835 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG01_584 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BG01_5845 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG01_5849 ENOG4108J59 Extracellular solute-binding protein, family 5 BG01_5855 ENOG4105N14 lysine exporter protein LysE YggA BG01_586 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BG01_5863 ENOG4105C3F Signal peptidase i BG01_5882 ENOG4105EWC Purine nucleoside phosphorylase BG01_5889 ENOG4105DQ6 Transposase BG01_589 ENOG4105E0A ABC, transporter BG01_5894 ENOG4107QJE Chromosome Partitioning Protein BG01_59 ENOG4105D8X mechanosensitive ion channel BG01_590 ENOG4105KFN sortase, SrtB family BG01_593 ENOG4105DR4 Methyltransferase BG01_596 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG01_60 ENOG4108ZDA Sporulation protein YyaC BG01_605 ENOG4105S6R Iron-hydroxamate transporter permease subunit BG01_606 ENOG4105J76 Periplasmic binding protein BG01_608 ENOG4105CEY Amp-dependent synthetase and ligase BG01_609 ENOG4107Z3H Transcriptional regulator, TetR family BG01_61 ENOG4105FA0 parb-like partition protein BG01_610 ENOG41060WC Enoyl-CoA hydratase BG01_611 ENOG4105BZJ Electron transfer flavoprotein BG01_612 ENOG4105C10 Electron transfer flavoprotein BG01_613 ENOG4105K63 Thioredoxin BG01_616 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BG01_618 ENOG4105E33 succinate dehydrogenase BG01_62 ENOG4107QJE Chromosome Partitioning Protein BG01_620 ENOG4108VXD carboxy-peptidase BG01_621 ENOG4105E14 MotA TolQ exbB proton channel BG01_622 ENOG4105ER2 Ompa motb domain protein BG01_623 ENOG4105ER2 Ompa motb domain protein BG01_624 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BG01_625 ENOG4108IUX (ABC) transporter BG01_626 ENOG4105RHA ABC transporter, permease BG01_627 ENOG4108Z40 Transcriptional regulator BG01_628 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BG01_630 ENOG4108JCI Transcriptional regulator BG01_631 ENOG41067S9 phage shock protein C, PspC BG01_634 ENOG4105DY9 regulatoR BG01_635 ENOG4108HRK Histidine kinase BG01_636 ENOG4108JQ7 (ABC) transporter BG01_639 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG01_640 ENOG4105DEF Extracellular solute-binding protein, family 5 BG01_641 ENOG4105DZC cytosine deaminase BG01_642 ENOG4105DZC cytosine deaminase BG01_645 ENOG4105PFC Transcriptional regulator BG01_648 ENOG4105KBX Transcriptional regulator, TetR family BG01_650 ENOG4108PCX Major Facilitator BG01_652 ENOG4108XJQ germination protein BG01_654 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BG01_655 ENOG4105M59 Phosphodiesterase, mj0936 family BG01_659 ENOG4108QCI YvbH-like oligomerisation region BG01_66 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BG01_665 ENOG4108IUQ atp-dependent protease BG01_669 ENOG4105K56 Transcriptional regulator BG01_674 ENOG4105D52 delta-aminolevulinic acid dehydratase BG01_676 ENOG41068KH stage VI sporulation protein D BG01_678 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BG01_679 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BG01_68 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BG01_683 ENOG4105DFF Rod shape-determining protein mreb BG01_684 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BG01_687 ENOG4107QMS site-determining protein BG01_690 ENOG4105C03 ribonuclease BG01_692 ENOG4105X36 (ribosomal) protein BG01_695 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BG01_698 ENOG4105EWM Histidine kinase BG01_7 ENOG4105JEU Glycosyl transferase, family 2 BG01_702 ENOG4105CQC Prephenate dehydratase BG01_703 ENOG4108RPX mosc domain containing protein BG01_706 ENOG4108IYU L-aspartate oxidase BG01_707 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BG01_712 ENOG41082BM Transcriptional regulator, arsr family BG01_713 ENOG4108IPJ Membrane BG01_714 ENOG4108IPJ Membrane BG01_716 ENOG4108HUF Transporter BG01_719 ENOG41061AI Protein of unknown function (DUF2905) BG01_72 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BG01_722 ENOG4105VIE preprotein translocase, subunit YajC BG01_724 ENOG4108QG2 Membrane BG01_725 ENOG4105CKP Polysaccharide Biosynthesis Protein BG01_727 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BG01_728 ENOG41076HS cation diffusion facilitator family transporter BG01_729 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BG01_73 ENOG410848D S4 domain protein YaaA BG01_731 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BG01_734 ENOG4105CUT histidyl-tRNA synthetase BG01_736 ENOG4105CUZ uba thif-type nad fad binding protein BG01_737 ENOG4108VCI transcription factor, rsfa family BG01_738 ENOG4105D1H recombination factor protein RarA BG01_740 ENOG4105C3J Cysteine desulfurase BG01_741 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BG01_743 ENOG4105C7H Helicase, RecD TraA family BG01_744 ENOG41060CR BG01_747 ENOG4105C02 permease BG01_749 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG01_753 ENOG4105HHA aminodeoxychorismate lyase BG01_754 ENOG4108VQJ O-methyltransferase BG01_755 ENOG4105XYU peptidase (U32 family) BG01_756 ENOG4105CFP Peptidase U32 BG01_759 ENOG4107XRG penicillin-binding protein BG01_76 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BG01_765 ENOG4105C28 cystathionine BG01_766 ENOG4108EKI Dehydrogenase BG01_768 ENOG4108V5C ABC transporter BG01_769 ENOG4105S6R Iron-hydroxamate transporter permease subunit BG01_777 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_778 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG01_780 ENOG4105MIR Phenylalanine 4-monooxygenase BG01_781 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BG01_788 ENOG4108MUZ hydrolase BG01_790 ENOG4105G6Z alkaline phosphatase BG01_793 ENOG4108TVJ Nitroreductase BG01_798 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_8 ENOG4105C5H ABC transporter BG01_800 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BG01_801 ENOG4105CQW ribosome biogenesis GTPase YqeH BG01_803 ENOG410812S Rna-binding protein BG01_805 ENOG4108WF2 Metal Dependent Phosphohydrolase BG01_807 ENOG4105DXX methyltransferase BG01_809 ENOG4105KQC Competence protein BG01_810 ENOG4108UK2 deaminase BG01_814 ENOG4105TQK DNA polymerase iii, delta' subunit BG01_819 ENOG4105KVH Transcriptional regulator BG01_82 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BG01_820 ENOG4105CSA Coproporphyrinogen iii oxidase BG01_822 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BG01_826 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BG01_827 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BG01_829 ENOG4105KTH gatB Yqey BG01_830 ENOG41068P3 sporulation protein YqfC BG01_832 ENOG4105C9A Phoh family BG01_833 ENOG4105CTJ Metal Dependent Phosphohydrolase BG01_835 ENOG4107YR5 Diacylglycerol kinase BG01_836 ENOG4105KG3 cytidine deaminase BG01_837 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BG01_842 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BG01_843 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG01_846 ENOG4105EGD dinuclear metal center protein, YbgI family BG01_851 ENOG41069ZM Protein of unknown function (DUF2624) BG01_852 ENOG4108JYZ YitT family BG01_853 ENOG4105FDK ABC transporter BG01_855 ENOG4105N80 Ferric uptake regulator, Fur family BG01_860 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG01_862 ENOG4107RF6 penicillin-binding protein BG01_863 ENOG4105PWN phosphate abc transporter BG01_864 ENOG4105C8U phosphate abc transporter BG01_865 ENOG4105E2Z phosphate ABC transporter (Permease BG01_866 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BG01_867 ENOG4108UTW Plays a role in the regulation of phosphate uptake BG01_870 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BG01_872 ENOG4105DKQ ROK family BG01_874 ENOG4105C5X domain protein BG01_878 ENOG4105C28 cystathionine BG01_879 ENOG4105C28 cystathionine BG01_881 ENOG4105C3R Methionine synthase BG01_882 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BG01_89 ENOG4105ZMH deoxynucleoside kinase BG01_906 ENOG4105C0D helicase BG01_91 ENOG4105GTG Isochorismatase BG01_912 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG01_913 ENOG4105CJ1 ABC, transporter BG01_92 ENOG4108Z6B deaminase BG01_920 ENOG41080TC multidrug resistance protein BG01_924 ENOG4105WZW rhodanese family BG01_925 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BG01_93 ENOG4105C6E dna polymerase iii BG01_930 ENOG4107YBY Hydrolase BG01_931 ENOG4105CBJ Metal-dependent enzyme BG01_934 ENOG4105DC7 peptidase M24 BG01_939 ENOG4105CD2 stage iii sporulation protein aa BG01_940 ENOG4105KR5 Stage iii sporulation protein BG01_941 ENOG4108CQH stage III sporulation protein AC BG01_942 ENOG4105KQ4 Stage iii sporulation protein ad BG01_944 ENOG410644B Stage III sporulation protein af BG01_949 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BG01_950 ENOG4108ZSR alkaline shock protein BG01_955 ENOG4105CTB Polyprenyl synthetase BG01_957 ENOG4105DX0 Hemolysin A BG01_959 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BG01_960 ENOG4105S1Z Stage IV sporulation protein B BG01_961 ENOG4107QQR Sporulation BG01_964 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BG01_966 ENOG4108JUB Transcriptional regulator BG01_968 ENOG4107RDP Dehydrogenase BG01_97 ENOG41067KS pro-sigma K processing BG01_972 ENOG4105CPP Dehydrogenase, E1 component BG01_973 ENOG4105C7S Dehydrogenase BG01_975 ENOG4105E09 nadh pyrophosphatase BG01_976 ENOG4105G7B Protein of unknown function (DUF2992) BG01_978 ENOG4108HW3 (ABC) transporter BG01_979 ENOG4105E5Q amino acid AbC transporter BG01_980 ENOG4105CDA abc transporter atp-binding protein BG01_981 ENOG4108QEG Membrane BG01_982 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BG01_984 ENOG4105D9U N-acetyltransferase BG01_985 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BG01_987 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG01_991 ENOG4105EJQ L-serine dehydratase BG01_992 ENOG4105II7 pyrroline-5-carboxylate reductase BG01_994 ENOG41069FQ Metallo-beta-lactamase superfamily BG01_995 ENOG4108IXY short-chain dehydrogenase reductase BG01_998 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)