locus-tag	class	description
BF89_1	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF89_100	COG1396	sequence-specific DNA binding
BF89_1001	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF89_1002	COG4862	establishment of competence for transformation
BF89_1004	COG1408	metallophosphoesterase
BF89_1006	COG1266	CAAX protease self-immunity
BF89_1007	COG0514	ATP-dependent DNA helicase (RecQ)
BF89_1008	COG4955	Helix-turn-helix domain
BF89_1009	COG1141	Ferredoxin
BF89_1010	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF89_1013	COG2096	Adenosyltransferase
BF89_1014	COG5002	protein histidine kinase activity
BF89_1015	COG0745	RESPONSE REGULATOR receiver
BF89_1016	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF89_1017	COG1333	cytochrome c biogenesis protein
BF89_1019	COG1187	pseudouridine synthase activity
BF89_1020	COG0700	Nucleoside recognition
BF89_1021	COG2715	membrane protein required for spore maturation
BF89_1022	COG1686	Belongs to the peptidase S11 family
BF89_1023	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_1026	COG0392	lysyltransferase activity
BF89_1026	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF89_1030	COG5002	protein histidine kinase activity
BF89_1031	COG0582	viral genome integration into host DNA
BF89_1033	COG1801	Protein of unknown function DUF72
BF89_1034	COG3852	Histidine kinase
BF89_1037	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_1038	COG1392	Phosphate transport regulator
BF89_1039	COG0306	phosphate transporter
BF89_104	COG1132	(ABC) transporter
BF89_1040	COG0730	response to heat
BF89_1043	COG1017	nitric oxide dioxygenase activity
BF89_1043	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF89_1048	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF89_105	COG1132	(ABC) transporter
BF89_1050	COG1114	Component of the transport system for branched-chain amino acids
BF89_1052	COG2197	response regulator
BF89_1053	COG4585	Histidine kinase
BF89_1054	COG4758	membrane
BF89_1057	COG1757	Na H antiporter
BF89_1061	COG0733	neurotransmitter:sodium symporter activity
BF89_1062	COG1648	precorrin-2 dehydrogenase activity
BF89_1066	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF89_1067	COG0529	Catalyzes the synthesis of activated sulfate
BF89_1071	COG0019	diaminopimelate decarboxylase activity
BF89_1073	COG1368	sulfuric ester hydrolase activity
BF89_1074	COG1183	phosphatidylcholine synthase activity
BF89_1077	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF89_108	COG2258	MOSC domain
BF89_1084	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF89_1089	COG0473	3-isopropylmalate dehydrogenase activity
BF89_109	COG0583	DNA-binding transcription factor activity
BF89_1091	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF89_1092	COG0440	acetolactate synthase activity
BF89_1093	COG0028	Belongs to the TPP enzyme family
BF89_1094	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_1099	COG3874	Sporulation protein YtfJ
BF89_11	COG1131	(ABC) transporter
BF89_1100	COG4709	membrane
BF89_1101	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_1102	COG1301	dicarboxylic acid transport
BF89_1104	COG1846	Transcriptional regulator
BF89_1107	COG1968	undecaprenyl-diphosphatase activity
BF89_1108	COG0534	Mate efflux family protein
BF89_1112	COG3173	Aminoglycoside phosphotransferase
BF89_1115	COG0716	FMN binding
BF89_112	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF89_1120	COG1696	Membrane protein involved in D-alanine export
BF89_1122	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF89_1123	COG2070	2-Nitropropane dioxygenase
BF89_1124	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_1126	COG1335	isochorismatase
BF89_1128	COG1522	sequence-specific DNA binding
BF89_113	COG0583	DNA-binding transcription factor activity
BF89_1131	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_1132	COG1131	(ABC) transporter
BF89_1134	COG1131	(ABC) transporter
BF89_1135	COG1725	Transcriptional regulator
BF89_1136	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF89_1137	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF89_1139	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF89_1140	COG1780	Probably involved in ribonucleotide reductase function
BF89_1146	COG4873	Protein conserved in bacteria
BF89_1149	COG0720	synthase
BF89_1151	COG5002	protein histidine kinase activity
BF89_1153	COG2318	DinB family
BF89_1155	COG1846	Transcriptional regulator
BF89_1156	COG3852	Histidine kinase
BF89_1158	COG2861	carbohydrate metabolic process
BF89_1161	COG0235	Class ii aldolase
BF89_1166	COG1349	DNA-binding transcription factor activity
BF89_1170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF89_1173	COG3842	ATPase activity
BF89_1174	COG3842	ATPase activity
BF89_1176	COG1840	ABC-type Fe3 transport system, periplasmic component
BF89_1179	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_1181	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF89_1182	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_1186	COG2030	dehydratase
BF89_1188	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_1189	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_1190	COG0861	Integral membrane protein TerC family
BF89_1191	COG2116	formate transmembrane transporter activity
BF89_1193	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF89_1197	COG2186	Transcriptional regulator
BF89_1198	COG5002	protein histidine kinase activity
BF89_1199	COG0745	RESPONSE REGULATOR receiver
BF89_1201	COG3835	regulator
BF89_1202	COG0277	FAD linked oxidase domain protein
BF89_1203	COG0247	lactate metabolic process
BF89_1204	COG2340	Cysteine-rich secretory protein family
BF89_1206	COG0564	pseudouridine synthase activity
BF89_1208	COG2409	Drug exporters of the RND superfamily
BF89_121	COG0561	phosphatase activity
BF89_1210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF89_1211	COG1177	transmembrane transport
BF89_1212	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF89_1213	COG3842	ATPase activity
BF89_1214	COG1012	belongs to the aldehyde dehydrogenase family
BF89_122	COG0010	Belongs to the arginase family
BF89_1220	COG0681	Belongs to the peptidase S26 family
BF89_1221	COG1686	Belongs to the peptidase S11 family
BF89_1223	COG2226	methyltransferase
BF89_1234	COG1476	TRANSCRIPTIONal
BF89_1236	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_1246	COG5634	Uncharacterized conserved protein (DUF2278)
BF89_1247	COG1620	l-lactate permease
BF89_125	COG1278	Cold shock
BF89_1254	COG0512	Glutamine amidotransferase of anthranilate synthase
BF89_1254	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF89_1256	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_1257	COG5492	domain, Protein
BF89_1260	COG2382	esterase
BF89_1261	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF89_1262	COG2153	protein acetylation
BF89_127	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_1270	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF89_1273	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF89_1277	COG0463	Glycosyl transferase, family 2
BF89_1277	COG0457	Tetratricopeptide repeat
BF89_1281	COG1216	Glycosyl transferase, family 2
BF89_1282	COG0772	Belongs to the SEDS family
BF89_1283	COG0772	Belongs to the SEDS family
BF89_1286	COG0564	pseudouridine synthase activity
BF89_1287	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF89_1288	COG2357	RelA SpoT domain protein
BF89_1290	COG4116	CYTH
BF89_1291	COG2346	COG2346, Truncated hemoglobins
BF89_1294	COG1164	Oligoendopeptidase f
BF89_1296	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_1297	COG4862	establishment of competence for transformation
BF89_1298	COG0861	Integral membrane protein TerC family
BF89_1299	COG1393	Belongs to the ArsC family
BF89_1301	COG4166	transmembrane transport
BF89_1302	COG0534	Mate efflux family protein
BF89_1303	COG4608	Belongs to the ABC transporter superfamily
BF89_1304	COG0444	Belongs to the ABC transporter superfamily
BF89_1305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_1306	COG0601	transmembrane transport
BF89_1307	COG4166	transmembrane transport
BF89_1309	COG0180	Tryptophanyl-tRNA synthetase
BF89_1311	COG5504	Zn-dependent protease
BF89_1312	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF89_1313	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_1316	COG2267	carboxylic ester hydrolase activity
BF89_1318	COG0542	response to heat
BF89_1320	COG0561	phosphatase activity
BF89_1323	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_1324	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_1326	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_1328	COG2996	Protein conserved in bacteria
BF89_1333	COG0004	ammonium transporteR
BF89_1334	COG0753	catalase activity
BF89_1336	COG0367	asparagine synthase
BF89_1341	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF89_1349	COG1074	ATP-dependent DNA helicase activity
BF89_135	COG1247	-acetyltransferase
BF89_1350	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF89_1352	COG0398	Pfam SNARE associated Golgi protein
BF89_1353	COG4903	ComK protein
BF89_1356	COG1278	Cold shock
BF89_1358	COG2224	Isocitrate lyase
BF89_1359	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF89_1360	COG0497	DNA recombination
BF89_1363	COG0697	spore germination
BF89_1364	COG0840	transmembrane signaling receptor activity
BF89_1365	COG0501	Belongs to the peptidase M48B family
BF89_1370	COG0745	RESPONSE REGULATOR receiver
BF89_1371	COG2205	protein histidine kinase activity
BF89_1374	COG2207	Transcriptional regulator
BF89_1374	COG3708	Transcriptional regulator
BF89_1375	COG1595	DNA-templated transcription, initiation
BF89_1377	COG1078	dGTPase activity
BF89_1378	COG1408	metallophosphoesterase
BF89_1385	COG3209	COG3209 Rhs family protein
BF89_1391	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_1393	COG0095	Lipoate-protein ligase
BF89_1394	COG1234	tRNA 3'-trailer cleavage
BF89_1396	COG1609	Transcriptional regulator
BF89_14	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_1401	COG1511	domain protein
BF89_1402	COG1309	transcriptional regulator
BF89_1411	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF89_1412	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_1413	COG2329	Antibiotic biosynthesis monooxygenase
BF89_1414	COG3428	Bacterial PH domain
BF89_1415	COG3402	PFAM membrane-flanked domain
BF89_142	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_1423	COG3428	Bacterial PH domain
BF89_1425	COG3402	PFAM membrane-flanked domain
BF89_1427	COG1309	transcriptional regulator
BF89_1430	COG4473	ABC transporter
BF89_1431	COG1131	(ABC) transporter
BF89_1432	COG0537	adenosine 5'-monophosphoramidase activity
BF89_1433	COG4980	gas vesicle protein
BF89_1437	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_1438	COG3973	AAA domain
BF89_1440	COG0477	Major facilitator Superfamily
BF89_1441	COG0477	Major facilitator Superfamily
BF89_1449	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF89_1451	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF89_1452	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF89_1457	COG2267	carboxylic ester hydrolase activity
BF89_1458	COG0457	Tetratricopeptide repeat
BF89_1459	COG0346	lactoylglutathione lyase activity
BF89_1460	COG0346	lactoylglutathione lyase activity
BF89_1461	COG2814	Major facilitator Superfamily
BF89_1462	COG1309	transcriptional regulator
BF89_1466	COG4717	serine-type aminopeptidase activity
BF89_1467	COG0420	3'-5' exonuclease activity
BF89_1473	COG0393	Putative heavy-metal-binding
BF89_1478	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_1478	COG0784	Response regulator, receiver
BF89_1478	COG2205	protein histidine kinase activity
BF89_1478	COG2198	Histidine kinase
BF89_1479	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF89_1480	COG2208	phosphoserine phosphatase activity
BF89_1482	COG1191	sigma factor activity
BF89_1487	COG3237	CsbD-like
BF89_1498	COG2770	Histidine kinase
BF89_1498	COG3437	response regulator, receiver
BF89_1503	COG1959	2 iron, 2 sulfur cluster binding
BF89_1504	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_1505	COG2376	Dihydroxyacetone kinase
BF89_1507	COG2376	Dihydroxyacetone kinase
BF89_151	COG2226	methyltransferase
BF89_1511	COG1183	phosphatidylcholine synthase activity
BF89_1516	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF89_1516	COG3320	Male sterility
BF89_1527	COG0477	Major facilitator Superfamily
BF89_1535	COG0305	Participates in initiation and elongation during chromosome replication
BF89_1538	COG0789	Transcriptional regulator
BF89_1538	COG4978	Transcriptional regulator
BF89_1543	COG3181	Tripartite tricarboxylate transporter family receptor
BF89_1544	COG4565	transcriptional regulatory protein
BF89_1545	COG3290	protein histidine kinase activity
BF89_1546	COG0477	Major facilitator Superfamily
BF89_1552	COG4608	Belongs to the ABC transporter superfamily
BF89_1553	COG0444	Belongs to the ABC transporter superfamily
BF89_1554	COG0444	Belongs to the ABC transporter superfamily
BF89_1555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_1556	COG0601	transmembrane transport
BF89_156	COG2814	Major facilitator Superfamily
BF89_1563	COG3938	Belongs to the proline racemase family
BF89_1567	COG1363	Peptidase, m42
BF89_157	COG0596	Alpha beta hydrolase
BF89_1570	COG1024	Enoyl-CoA hydratase
BF89_1573	COG1696	Membrane protein involved in D-alanine export
BF89_1576	COG4196	transglutaminase domain protein
BF89_1577	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_1579	COG2244	polysaccharide biosynthetic process
BF89_1580	COG0653	protein targeting
BF89_1584	COG0659	secondary active sulfate transmembrane transporter activity
BF89_1587	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF89_1589	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_1589	COG3409	Peptidoglycan-binding domain 1 protein
BF89_1591	COG0561	phosphatase activity
BF89_1594	COG3527	Alpha-acetolactate decarboxylase
BF89_1595	COG0028	Belongs to the TPP enzyme family
BF89_160	COG1136	(ABC) transporter
BF89_1601	COG0189	ligase activity
BF89_1604	COG1126	abc transporter atp-binding protein
BF89_1605	COG0765	amino acid transport
BF89_1606	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_1607	COG1132	(ABC) transporter
BF89_1608	COG1132	(ABC) transporter
BF89_1609	COG1132	(ABC) transporter
BF89_161	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_1610	COG1012	belongs to the aldehyde dehydrogenase family
BF89_1612	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF89_1613	COG0531	amino acid
BF89_1615	COG0693	protein deglycase activity
BF89_1615	COG0753	catalase activity
BF89_1616	COG0693	protein deglycase activity
BF89_1618	COG2814	Major facilitator Superfamily
BF89_1619	COG4533	DNA binding
BF89_162	COG1187	pseudouridine synthase activity
BF89_1620	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_1622	COG1733	regulation of RNA biosynthetic process
BF89_1623	COG2814	Major facilitator Superfamily
BF89_1624	COG1309	transcriptional regulator
BF89_1625	COG2076	Multidrug Resistance protein
BF89_1626	COG2076	Multidrug Resistance protein
BF89_1628	COG1522	sequence-specific DNA binding
BF89_1629	COG0697	spore germination
BF89_163	COG2329	Antibiotic biosynthesis monooxygenase
BF89_1632	COG2259	Doxx family
BF89_1634	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_1634	COG1263	PTS System
BF89_1636	COG1737	Transcriptional regulator
BF89_1638	COG0475	glutathione-regulated potassium exporter activity
BF89_1639	COG0531	amino acid
BF89_1646	COG0586	Pfam SNARE associated Golgi protein
BF89_1653	COG3546	catalase activity
BF89_1654	COG1114	Component of the transport system for branched-chain amino acids
BF89_1657	COG5522	Integral membrane protein (intg_mem_TP0381)
BF89_1659	COG1136	(ABC) transporter
BF89_166	COG1115	amino acid carrier protein
BF89_1660	COG0577	efflux transmembrane transporter activity
BF89_1661	COG1388	LysM domain
BF89_1661	COG3584	3D domain protein
BF89_1665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_1666	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_1667	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_1667	COG3711	transcriptional antiterminator
BF89_167	COG1115	amino acid carrier protein
BF89_1670	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF89_1671	COG0604	alcohol dehydrogenase
BF89_1672	COG1316	TRANSCRIPTIONal
BF89_1674	COG0730	response to heat
BF89_1675	COG2210	Belongs to the sulfur carrier protein TusA family
BF89_1677	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_1679	COG0425	Belongs to the sulfur carrier protein TusA family
BF89_1680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_1680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_1681	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_1681	COG0425	Belongs to the sulfur carrier protein TusA family
BF89_1682	COG1937	Protein conserved in bacteria
BF89_1683	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF89_1688	COG2719	SpoVR family
BF89_1689	COG0778	Nitroreductase
BF89_169	COG2318	DinB family
BF89_1696	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF89_1697	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_1699	COG1609	Transcriptional regulator
BF89_1700	COG1263	PTS System
BF89_1700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_1701	COG1621	beta-fructofuranosidase activity
BF89_1702	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF89_1704	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_1705	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_1706	COG2252	PERMEase
BF89_1709	COG1846	Transcriptional regulator
BF89_171	COG0776	regulation of translation
BF89_1710	COG2814	Major facilitator Superfamily
BF89_1711	COG2205	protein histidine kinase activity
BF89_1718	COG0351	phosphomethylpyrimidine kinase
BF89_1719	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_1721	COG2104	thiamine diphosphate biosynthetic process
BF89_1722	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_1723	COG0352	thiamine-phosphate diphosphorylase activity
BF89_1724	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_1725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_1726	COG1116	anion transmembrane transporter activity
BF89_1727	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF89_1731	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF89_174	COG2814	Major facilitator Superfamily
BF89_175	COG3251	PFAM MbtH domain protein
BF89_1756	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF89_1758	COG0581	inorganic phosphate transmembrane transporter activity
BF89_1759	COG0573	inorganic phosphate transmembrane transporter activity
BF89_176	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF89_1760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF89_1761	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_1761	COG1918	ferrous iron import across plasma membrane
BF89_1762	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_1763	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_1765	COG0531	amino acid
BF89_1766	COG0697	spore germination
BF89_1767	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_177	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF89_1770	COG4990	cell redox homeostasis
BF89_1771	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF89_1772	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF89_1775	COG0569	domain protein
BF89_1775	COG0475	glutathione-regulated potassium exporter activity
BF89_178	COG3433	isochorismatase activity
BF89_178	COG1535	isochorismatase
BF89_1780	COG2252	PERMEase
BF89_1781	COG1113	amino acid transport
BF89_1784	COG1114	Component of the transport system for branched-chain amino acids
BF89_1785	COG3104	oligopeptide transport
BF89_1788	COG1476	TRANSCRIPTIONal
BF89_1789	COG1388	LysM domain
BF89_1789	COG3584	3D domain protein
BF89_179	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF89_1790	COG0840	transmembrane signaling receptor activity
BF89_1791	COG1968	undecaprenyl-diphosphatase activity
BF89_1796	COG3568	Endonuclease Exonuclease Phosphatase
BF89_1799	COG1063	alcohol dehydrogenase
BF89_18	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_180	COG1169	isochorismate synthase
BF89_1803	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF89_1804	COG1879	ABC-type sugar transport system periplasmic component
BF89_1805	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF89_1806	COG1129	ABC transporter
BF89_1808	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF89_1809	COG1609	Transcriptional regulator
BF89_181	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_1810	COG0477	Major facilitator Superfamily
BF89_1811	COG0477	Major facilitator Superfamily
BF89_1812	COG1846	Transcriptional regulator
BF89_1813	COG2271	Major facilitator Superfamily
BF89_1815	COG4608	Belongs to the ABC transporter superfamily
BF89_1816	COG0601	transmembrane transport
BF89_1818	COG0747	negative chemotaxis
BF89_182	COG2223	nitrite transmembrane transporter activity
BF89_1821	COG0659	secondary active sulfate transmembrane transporter activity
BF89_1824	COG5002	protein histidine kinase activity
BF89_1825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF89_1826	COG2378	regulation of single-species biofilm formation
BF89_1831	COG0833	amino acid
BF89_1832	COG0765	amino acid transport
BF89_1833	COG0765	amino acid transport
BF89_1834	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_1835	COG1126	abc transporter atp-binding protein
BF89_1836	COG1115	amino acid carrier protein
BF89_1837	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_1839	COG0697	spore germination
BF89_1842	COG0366	Alpha amylase catalytic
BF89_1843	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_1843	COG1263	PTS System
BF89_1844	COG2188	Transcriptional regulator
BF89_1845	COG0531	amino acid
BF89_1849	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_1850	COG0714	Associated with various cellular activities
BF89_1851	COG4548	von Willebrand factor, type A
BF89_1853	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_1854	COG0156	8-amino-7-oxononanoate synthase activity
BF89_1855	COG2226	methyltransferase
BF89_1857	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_1858	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_1859	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_186	COG0419	ATPase involved in DNA repair
BF89_1860	COG3104	oligopeptide transport
BF89_1863	COG1620	l-lactate permease
BF89_1864	COG1027	Aspartate ammonia-lyase
BF89_1865	COG1253	flavin adenine dinucleotide binding
BF89_1866	COG0346	lactoylglutathione lyase activity
BF89_1867	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_1868	COG1316	TRANSCRIPTIONal
BF89_1869	COG2720	vancomycin resistance protein
BF89_187	COG0420	3'-5' exonuclease activity
BF89_1873	COG3227	Zinc metalloprotease (Elastase)
BF89_1876	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF89_1877	COG2217	Heavy metal translocating P-type atpase
BF89_1878	COG0640	Transcriptional regulator
BF89_1879	COG0531	amino acid
BF89_1882	COG2427	Protein of unknown function (DUF1641)
BF89_1884	COG3383	formate dehydrogenase (NAD+) activity
BF89_1885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF89_1886	COG0456	acetyltransferase
BF89_1886	COG0454	-acetyltransferase
BF89_1888	COG0745	RESPONSE REGULATOR receiver
BF89_1889	COG5002	protein histidine kinase activity
BF89_1891	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_1894	COG0281	malic enzyme
BF89_1895	COG3493	citrate carrier protein
BF89_1896	COG4565	transcriptional regulatory protein
BF89_1897	COG3290	protein histidine kinase activity
BF89_1899	COG4990	cell redox homeostasis
BF89_190	COG1024	Enoyl-CoA hydratase
BF89_1901	COG5002	protein histidine kinase activity
BF89_1902	COG0745	RESPONSE REGULATOR receiver
BF89_1903	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF89_1906	COG0395	ABC-type sugar transport system, permease component
BF89_1907	COG1175	transmembrane transport
BF89_1908	COG3842	ATPase activity
BF89_1909	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF89_191	COG1280	lysine exporter protein (LysE YggA)
BF89_1913	COG2851	Citrate transporter
BF89_1914	COG4565	transcriptional regulatory protein
BF89_1915	COG3290	protein histidine kinase activity
BF89_1917	COG2268	Band 7 protein
BF89_1918	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF89_192	COG1012	belongs to the aldehyde dehydrogenase family
BF89_1920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_1924	COG2766	serine protein kinase
BF89_1927	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF89_1929	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF89_193	COG2084	Dehydrogenase
BF89_1931	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF89_1932	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF89_194	COG1960	acyl-CoA dehydrogenase activity
BF89_195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF89_1957	COG0735	belongs to the Fur family
BF89_1958	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF89_196	COG2079	MmgE PrpD family protein
BF89_1962	COG4555	ABC transporter
BF89_1964	COG0070	glutamate synthase
BF89_1964	COG0069	glutamate synthase activity
BF89_1964	COG0067	glutamate synthase
BF89_1965	COG4129	membrane
BF89_1966	COG1132	(ABC) transporter
BF89_197	COG0372	Belongs to the citrate synthase family
BF89_1971	COG1194	a g-specific adenine glycosylase
BF89_1972	COG1988	membrane-bound metal-dependent
BF89_1978	COG1090	epimerase
BF89_1979	COG1228	amidohydrolase
BF89_198	COG4841	protein insertion into membrane
BF89_1983	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF89_1986	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_1986	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF89_1989	COG0463	Glycosyl transferase, family 2
BF89_199	COG2814	Major facilitator Superfamily
BF89_1992	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_1993	COG1263	PTS System
BF89_1993	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_1994	COG2066	Belongs to the glutaminase family
BF89_1999	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_2	COG1024	Enoyl-CoA hydratase
BF89_200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_200	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF89_2000	COG0833	amino acid
BF89_2002	COG3829	transcription factor binding
BF89_2004	COG0101	tRNA pseudouridine synthase activity
BF89_2029	COG0582	viral genome integration into host DNA
BF89_2030	COG0582	viral genome integration into host DNA
BF89_2051	COG1484	DNA-dependent DNA replication
BF89_2058	COG1396	sequence-specific DNA binding
BF89_2062	COG0582	viral genome integration into host DNA
BF89_2063	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF89_2064	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF89_2069	COG0535	radical SAM domain protein
BF89_2071	COG0387	Pfam Sodium calcium exchanger
BF89_2072	COG3871	stress protein (general stress protein 26)
BF89_2075	COG0586	Pfam SNARE associated Golgi protein
BF89_2078	COG0681	Belongs to the peptidase S26 family
BF89_208	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_2080	COG0697	spore germination
BF89_2081	COG2217	Heavy metal translocating P-type atpase
BF89_2082	COG1295	ribonuclease BN
BF89_2084	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF89_2087	COG3853	Toxic anion resistance protein (TelA)
BF89_2089	COG0861	Integral membrane protein TerC family
BF89_2090	COG2310	stress, protein
BF89_2091	COG2310	stress, protein
BF89_2092	COG2310	stress, protein
BF89_2095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_2098	COG2270	Major facilitator Superfamily
BF89_2108	COG0488	(ABC) transporter
BF89_2109	COG1116	anion transmembrane transporter activity
BF89_2111	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_2114	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF89_2120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_2120	COG2190	(PTS) system
BF89_2120	COG1263	PTS System
BF89_2121	COG0366	Alpha amylase catalytic
BF89_2122	COG0840	transmembrane signaling receptor activity
BF89_2123	COG0840	transmembrane signaling receptor activity
BF89_2125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_2126	COG0765	amino acid transport
BF89_2128	COG0723	plastoquinol--plastocyanin reductase activity
BF89_2128	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_2129	COG2814	Major facilitator Superfamily
BF89_2130	COG3541	Predicted nucleotidyltransferase
BF89_2134	COG5002	protein histidine kinase activity
BF89_2140	COG0166	Belongs to the GPI family
BF89_2143	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_2144	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_2145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_2146	COG0235	Class ii aldolase
BF89_2148	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF89_2149	COG0450	alkyl hydroperoxide reductase
BF89_2152	COG1473	amidohydrolase
BF89_2158	COG4807	Protein conserved in bacteria
BF89_2160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF89_2161	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF89_2162	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_2165	COG2309	aminopeptidase activity
BF89_2166	COG2076	Multidrug Resistance protein
BF89_2167	COG1012	belongs to the aldehyde dehydrogenase family
BF89_2169	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF89_2170	COG0546	phosphoglycolate phosphatase activity
BF89_2171	COG1597	lipid kinase activity
BF89_2175	COG4682	membrane
BF89_2176	COG1846	Transcriptional regulator
BF89_2177	COG0003	Pfam Anion-transporting ATPase
BF89_2178	COG0003	Pfam Anion-transporting ATPase
BF89_2181	COG1464	Belongs to the NlpA lipoprotein family
BF89_2182	COG2011	ABC-type metal ion transport system permease component
BF89_2183	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_2184	COG1335	isochorismatase
BF89_2188	COG4851	CamS sex pheromone cAM373 precursor
BF89_2190	COG0210	DNA helicase
BF89_2195	COG0151	Belongs to the GarS family
BF89_2197	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF89_2199	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF89_22	COG1309	transcriptional regulator
BF89_2202	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF89_2204	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF89_2205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF89_2206	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF89_2211	COG0745	RESPONSE REGULATOR receiver
BF89_2212	COG2205	protein histidine kinase activity
BF89_2215	COG1968	undecaprenyl-diphosphatase activity
BF89_2221	COG5002	protein histidine kinase activity
BF89_2223	COG2252	PERMEase
BF89_2227	COG1266	CAAX protease self-immunity
BF89_2230	COG0488	(ABC) transporter
BF89_2231	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF89_2232	COG0456	acetyltransferase
BF89_2233	COG1214	PFAM Peptidase M22, glycoprotease
BF89_2234	COG0802	atpase or kinase
BF89_224	COG1787	Restriction endonuclease
BF89_224	COG1715	Restriction endonuclease
BF89_2253	COG2183	response to ionizing radiation
BF89_2254	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF89_2255	COG0864	Transcriptional regulator
BF89_2256	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF89_2257	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF89_2259	COG4294	response to UV
BF89_2260	COG0705	Rhomboid family
BF89_2260	COG0457	Tetratricopeptide repeat
BF89_2262	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF89_2265	COG2814	Major facilitator Superfamily
BF89_2267	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF89_2268	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF89_2272	COG0561	phosphatase activity
BF89_2273	COG0561	phosphatase activity
BF89_2274	COG4608	Belongs to the ABC transporter superfamily
BF89_2275	COG0444	Belongs to the ABC transporter superfamily
BF89_2277	COG0601	transmembrane transport
BF89_2278	COG0747	negative chemotaxis
BF89_2281	COG0488	(ABC) transporter
BF89_2285	COG5298	Protein conserved in bacteria
BF89_2286	COG0084	hydrolase, TatD family'
BF89_2289	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_229	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_2291	COG1609	Transcriptional regulator
BF89_2293	COG0204	Acyl-transferase
BF89_2296	COG0697	spore germination
BF89_2297	COG0583	DNA-binding transcription factor activity
BF89_230	COG0671	phosphoesterase, PA-phosphatase related
BF89_2300	COG1910	domain protein
BF89_2301	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF89_2302	COG4149	molybdate abc transporter
BF89_2305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_2306	COG0656	L-ascorbic acid biosynthetic process
BF89_2307	COG4166	transmembrane transport
BF89_2308	COG4166	transmembrane transport
BF89_231	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF89_2311	COG2207	Transcriptional regulator
BF89_2313	COG4166	transmembrane transport
BF89_2314	COG4608	Belongs to the ABC transporter superfamily
BF89_2315	COG0444	Belongs to the ABC transporter superfamily
BF89_2316	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_2317	COG0601	transmembrane transport
BF89_232	COG4326	sporulation control protein
BF89_2320	COG2814	Major facilitator Superfamily
BF89_2322	COG2271	Major facilitator Superfamily
BF89_2323	COG0277	FAD linked oxidase domain protein
BF89_2324	COG0277	FAD linked oxidase domain protein
BF89_2327	COG1464	Belongs to the NlpA lipoprotein family
BF89_2328	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_2329	COG2011	ABC-type metal ion transport system permease component
BF89_2330	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_2337	COG0823	Involved in the tonB-independent uptake of proteins
BF89_2337	COG1506	peptidase
BF89_2337	COG4946	Tricorn protease homolog
BF89_2338	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF89_2342	COG0596	Alpha beta hydrolase
BF89_2343	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF89_2345	COG4856	YbbR-like protein
BF89_2346	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF89_2364	COG0726	polysaccharide deacetylase
BF89_2365	COG2194	sulfuric ester hydrolase activity
BF89_2367	COG0489	protein tyrosine kinase activity
BF89_2368	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_2372	COG0101	tRNA pseudouridine synthase activity
BF89_2373	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF89_2374	COG1122	ATPase activity
BF89_2380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF89_2382	COG0024	Methionine aminopeptidase
BF89_2384	COG0201	protein transport
BF89_2389	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF89_240	COG1509	lysine 2,3-aminomutase activity
BF89_241	COG3829	transcription factor binding
BF89_2410	COG1358	cellular component organization or biogenesis
BF89_2411	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF89_2413	COG2813	Specifically methylates the guanine in position
BF89_2418	COG0250	Participates in transcription elongation, termination and antitermination
BF89_2419	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF89_242	COG0456	acetyltransferase
BF89_2421	COG3688	RNA-binding protein containing a PIN domain
BF89_2422	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF89_2425	COG1045	serine acetyltransferase
BF89_2429	COG4956	integral membrane protein (PIN domain superfamily)
BF89_243	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_2431	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF89_2432	COG0542	response to heat
BF89_2434	COG3880	PFAM UvrB UvrC protein
BF89_244	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF89_2441	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF89_2442	COG1396	sequence-specific DNA binding
BF89_2443	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF89_2444	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF89_2445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF89_2446	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_2447	COG0512	Glutamine amidotransferase of anthranilate synthase
BF89_2448	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF89_2449	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF89_2452	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF89_2454	COG0037	tRNA processing
BF89_2455	COG2208	phosphoserine phosphatase activity
BF89_2458	COG1098	S1 RNA binding domain
BF89_246	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_2462	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF89_2463	COG3956	TIGRFAM MazG family protein
BF89_2464	COG2244	polysaccharide biosynthetic process
BF89_2465	COG2002	toxin-antitoxin pair type II binding
BF89_2466	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF89_2468	COG0193	aminoacyl-tRNA hydrolase activity
BF89_2469	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF89_2472	COG0251	oxidation-reduction process
BF89_2473	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF89_2476	COG4466	Protein conserved in bacteria
BF89_2479	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF89_2480	COG0084	hydrolase, TatD family'
BF89_2481	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_2481	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_2482	COG2002	toxin-antitoxin pair type II binding
BF89_2483	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF89_2485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF89_2487	COG1774	PSP1 C-terminal conserved region
BF89_2488	COG0470	DNA polymerase III
BF89_249	COG5506	Protein of unknown function (DUF1694)
BF89_2490	COG1982	Orn Lys Arg decarboxylase major
BF89_250	COG1012	belongs to the aldehyde dehydrogenase family
BF89_2502	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF89_2503	COG0590	tRNA wobble adenosine to inosine editing
BF89_2504	COG1335	isochorismatase
BF89_2505	COG1428	Deoxynucleoside kinase
BF89_2506	COG1428	Deoxynucleoside kinase
BF89_251	COG1253	flavin adenine dinucleotide binding
BF89_2512	COG1686	Belongs to the peptidase S11 family
BF89_2513	COG0517	IMP dehydrogenase activity
BF89_2513	COG0516	GMP reductase activity
BF89_2521	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF89_2522	COG0187	DNA topoisomerase II activity
BF89_2524	COG2501	S4 domain
BF89_2525	COG0592	DNA-directed DNA polymerase activity
BF89_2529	COG0706	membrane insertase activity
BF89_2530	COG1847	R3H domain protein
BF89_2531	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF89_2535	COG1192	Involved in chromosome partitioning
BF89_2536	COG1475	DNA binding
BF89_2538	COG0668	transmembrane transport
BF89_2539	COG4481	Protein conserved in bacteria
BF89_2540	COG0012	GTP binding
BF89_2542	COG0629	single-stranded DNA binding
BF89_2544	COG4241	membrane
BF89_2545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF89_2547	COG0305	Participates in initiation and elongation during chromosome replication
BF89_2553	COG0745	RESPONSE REGULATOR receiver
BF89_2554	COG5002	protein histidine kinase activity
BF89_2555	COG4863	YycH protein
BF89_2556	COG4853	Protein conserved in bacteria
BF89_2557	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF89_2558	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_2562	COG1164	Oligoendopeptidase f
BF89_2567	COG1272	protein, Hemolysin III
BF89_2568	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF89_2572	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_2573	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF89_2574	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_2575	COG2814	Major facilitator Superfamily
BF89_2576	COG3275	phosphorelay sensor kinase activity
BF89_2577	COG3279	Response regulator of the LytR AlgR family
BF89_258	COG1174	glycine betaine transport
BF89_2580	COG0628	permease
BF89_2581	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_2581	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_2582	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF89_2583	COG1309	transcriptional regulator
BF89_2584	COG0463	Glycosyl transferase, family 2
BF89_2589	COG0488	(ABC) transporter
BF89_259	COG1125	glycine betaine transport
BF89_259	COG0517	IMP dehydrogenase activity
BF89_2592	COG1607	acyl-coa hydrolase
BF89_2594	COG0840	transmembrane signaling receptor activity
BF89_2595	COG0840	transmembrane signaling receptor activity
BF89_2600	COG0477	Major facilitator Superfamily
BF89_2601	COG3279	Response regulator of the LytR AlgR family
BF89_2602	COG1966	Carbon starvation protein
BF89_2603	COG2879	small protein
BF89_2604	COG3706	GGDEF domain
BF89_2605	COG0351	phosphomethylpyrimidine kinase
BF89_2606	COG2203	Gaf domain
BF89_2606	COG4585	Histidine kinase
BF89_2607	COG2203	Gaf domain
BF89_2607	COG4585	Histidine kinase
BF89_2608	COG2197	response regulator
BF89_2610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF89_2611	COG1011	Hydrolase
BF89_2615	COG0460	homoserine dehydrogenase
BF89_2617	COG1609	Transcriptional regulator
BF89_2618	COG2755	lipolytic protein G-D-S-L family
BF89_2619	COG1131	(ABC) transporter
BF89_2620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_2622	COG2814	Major facilitator Superfamily
BF89_2623	COG0561	phosphatase activity
BF89_2624	COG2233	PERMEase
BF89_2625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF89_2627	COG2363	Small membrane protein
BF89_2629	COG3773	Cell wall hydrolase
BF89_2632	COG0280	phosphate acetyltransferase
BF89_2633	COG0095	Lipoate-protein ligase
BF89_2637	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_2638	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_2639	COG1120	ATPase activity
BF89_2640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_2641	COG1078	dGTPase activity
BF89_2643	COG1994	Peptidase M50
BF89_2645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_2646	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_2647	COG0789	Transcriptional regulator
BF89_2648	COG2814	Major facilitator Superfamily
BF89_2649	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF89_2650	COG0010	Belongs to the arginase family
BF89_2653	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_2654	COG4506	Protein conserved in bacteria
BF89_2655	COG0018	arginyl-trna synthetase
BF89_2656	COG1595	DNA-templated transcription, initiation
BF89_266	COG1070	Carbohydrate kinase
BF89_2660	COG2234	aminopeptidase activity
BF89_2663	COG0024	Methionine aminopeptidase
BF89_2664	COG1131	(ABC) transporter
BF89_2665	COG0842	Transport permease protein
BF89_2666	COG4585	Histidine kinase
BF89_2667	COG2197	response regulator
BF89_2671	COG3300	MHYT domain
BF89_2671	COG5001	Diguanylate cyclase
BF89_2673	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_2674	COG2181	nitrate reductase activity
BF89_2674	COG0247	lactate metabolic process
BF89_2675	COG0183	Belongs to the thiolase family
BF89_2676	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF89_2677	COG1960	acyl-CoA dehydrogenase activity
BF89_2678	COG1960	acyl-CoA dehydrogenase activity
BF89_2680	COG3343	RNA polymerase activity
BF89_2682	COG4821	SIS domain
BF89_2685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF89_2686	COG1494	fructose-1,6-bisphosphatase
BF89_2687	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF89_2690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF89_2691	COG2890	protein-(glutamine-N5) methyltransferase activity
BF89_2694	COG0009	L-threonylcarbamoyladenylate synthase
BF89_2697	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF89_2698	COG2259	Doxx family
BF89_2699	COG2190	(PTS) system
BF89_27	COG1876	peptidase activity
BF89_2701	COG0698	ribose 5-phosphate isomerase
BF89_2707	COG0356	it plays a direct role in the translocation of protons across the membrane
BF89_2717	COG3300	MHYT domain
BF89_2717	COG5001	Diguanylate cyclase
BF89_2718	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF89_272	COG1064	alcohol dehydrogenase
BF89_2720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF89_2721	COG0649	NAD binding
BF89_2724	COG0839	Belongs to the complex I subunit 6 family
BF89_2726	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF89_2727	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF89_2728	COG1007	ATP synthesis coupled electron transport
BF89_2729	COG4836	Membrane
BF89_273	COG1737	Transcriptional regulator
BF89_2731	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF89_2732	COG2385	sporulation resulting in formation of a cellular spore
BF89_2733	COG4555	ABC transporter
BF89_2734	COG3279	Response regulator of the LytR AlgR family
BF89_2737	COG0739	heme binding
BF89_2739	COG1609	Transcriptional regulator
BF89_2747	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF89_2748	COG1682	transport, permease protein
BF89_2749	COG1134	teichoic acid transport
BF89_275	COG2197	response regulator
BF89_2750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF89_2753	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF89_2754	COG0745	RESPONSE REGULATOR receiver
BF89_2755	COG5002	protein histidine kinase activity
BF89_276	COG2203	Gaf domain
BF89_276	COG4585	Histidine kinase
BF89_2762	COG1136	(ABC) transporter
BF89_2763	COG0577	efflux transmembrane transporter activity
BF89_2765	COG1191	sigma factor activity
BF89_277	COG0668	transmembrane transport
BF89_2771	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_2772	COG4715	Zinc finger, swim domain protein
BF89_2777	COG3584	3D domain protein
BF89_2777	COG1388	LysM domain
BF89_2778	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_2780	COG1215	transferase activity, transferring glycosyl groups
BF89_2782	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_2783	COG1388	LysM domain
BF89_2783	COG0791	NLP P60 protein
BF89_2786	COG1368	sulfuric ester hydrolase activity
BF89_2789	COG2389	metal-binding protein
BF89_279	COG1051	belongs to the nudix hydrolase family
BF89_2791	COG1620	l-lactate permease
BF89_2793	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_2794	COG1294	oxidase, subunit
BF89_2795	COG1271	oxidase subunit
BF89_2798	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF89_2799	COG0583	DNA-binding transcription factor activity
BF89_280	COG1335	isochorismatase
BF89_2800	COG1511	domain protein
BF89_2801	COG0346	lactoylglutathione lyase activity
BF89_2803	COG1301	dicarboxylic acid transport
BF89_2804	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_2806	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_2807	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF89_2808	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF89_2810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_2811	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_2812	COG1486	melibiose metabolic process
BF89_2813	COG3394	polysaccharide catabolic process
BF89_2816	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF89_2816	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF89_2818	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF89_2819	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF89_2820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF89_2821	COG1316	TRANSCRIPTIONal
BF89_2822	COG1739	Uncharacterized protein family UPF0029
BF89_2823	COG1307	EDD domain protein, DegV family
BF89_2824	COG1733	regulation of RNA biosynthetic process
BF89_2825	COG0791	NLP P60 protein
BF89_2825	COG1388	LysM domain
BF89_2826	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF89_2827	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF89_2828	COG1040	competence protein
BF89_2829	COG1278	Cold shock
BF89_2830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF89_2831	COG0653	protein targeting
BF89_2832	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF89_2834	COG2884	Cell division ATP-binding protein ftsE
BF89_2835	COG2177	Part of the ABC transporter FtsEX involved in
BF89_2836	COG0793	Belongs to the peptidase S41A family
BF89_2836	COG3409	Peptidoglycan-binding domain 1 protein
BF89_2837	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_2838	COG1132	(ABC) transporter
BF89_284	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_2841	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF89_2843	COG0583	DNA-binding transcription factor activity
BF89_2844	COG2855	membrane
BF89_2848	COG0789	Transcriptional regulator
BF89_285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_2852	COG0556	nucleotide-excision repair
BF89_2853	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_2855	COG1950	PFAM Membrane protein of
BF89_2859	COG0110	maltose O-acetyltransferase activity
BF89_2860	COG0457	Tetratricopeptide repeat
BF89_2861	COG0492	ferredoxin-NADP+ reductase activity
BF89_2863	COG1051	belongs to the nudix hydrolase family
BF89_2865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF89_2867	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_2868	COG0740	serine-type endopeptidase activity
BF89_2869	COG2323	membrane
BF89_2872	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_2877	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF89_288	COG0367	asparagine synthase
BF89_2880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF89_2882	COG0149	triose-phosphate isomerase activity
BF89_2885	COG4974	Belongs to the 'phage' integrase family
BF89_2889	COG4695	Portal protein
BF89_289	COG0071	Belongs to the small heat shock protein (HSP20) family
BF89_290	COG1999	signal sequence binding
BF89_2908	COG1346	cytolysis
BF89_2909	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF89_291	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF89_2910	COG1647	Serine aminopeptidase, S33
BF89_2911	COG0557	exoribonuclease II activity
BF89_292	COG1307	EDD domain protein, DegV family
BF89_2920	COG3223	Belongs to the PsiE family
BF89_2921	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_2924	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF89_2925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF89_2927	COG3290	protein histidine kinase activity
BF89_2927	COG0840	transmembrane signaling receptor activity
BF89_2929	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF89_2930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF89_2931	COG1252	NADH dehydrogenase
BF89_2933	COG1733	regulation of RNA biosynthetic process
BF89_2934	COG2814	Major facilitator Superfamily
BF89_2935	COG0656	L-ascorbic acid biosynthetic process
BF89_294	COG0805	protein transport
BF89_2940	COG2910	NAD(P)H-binding
BF89_2941	COG1115	amino acid carrier protein
BF89_2942	COG1115	amino acid carrier protein
BF89_2943	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_2944	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_2946	COG2311	Membrane
BF89_2949	COG1611	Belongs to the LOG family
BF89_2952	COG0783	Belongs to the Dps family
BF89_2953	COG1115	amino acid carrier protein
BF89_2954	COG0490	domain, Protein
BF89_2955	COG0475	glutathione-regulated potassium exporter activity
BF89_2958	COG1741	Belongs to the pirin family
BF89_2959	COG3227	Zinc metalloprotease (Elastase)
BF89_296	COG1272	protein, Hemolysin III
BF89_2960	COG2151	metal-sulfur cluster biosynthetic enzyme
BF89_2963	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_2965	COG5002	protein histidine kinase activity
BF89_2966	COG0745	RESPONSE REGULATOR receiver
BF89_2967	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_2969	COG0586	Pfam SNARE associated Golgi protein
BF89_297	COG0204	Acyl-transferase
BF89_2976	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_2978	COG0706	membrane insertase activity
BF89_298	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_2980	COG0531	amino acid
BF89_2981	COG2814	Major facilitator Superfamily
BF89_2985	COG0840	transmembrane signaling receptor activity
BF89_2986	COG0011	TIGRFAM Protein of
BF89_2989	COG1686	Belongs to the peptidase S11 family
BF89_299	COG0768	penicillin binding
BF89_2991	COG1024	Enoyl-CoA hydratase
BF89_2991	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF89_2992	COG0183	Belongs to the thiolase family
BF89_2993	COG1960	acyl-CoA dehydrogenase activity
BF89_2994	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_2995	COG1309	transcriptional regulator
BF89_3	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF89_30	COG1476	TRANSCRIPTIONal
BF89_3000	COG0039	L-malate dehydrogenase activity
BF89_3009	COG1393	Belongs to the ArsC family
BF89_3011	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF89_3012	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_3014	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_3015	COG2011	ABC-type metal ion transport system permease component
BF89_3016	COG1464	Belongs to the NlpA lipoprotein family
BF89_3017	COG1464	Belongs to the NlpA lipoprotein family
BF89_3018	COG0396	ATPase activity
BF89_3019	COG0719	Fe-S assembly protein
BF89_302	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_3020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF89_3021	COG0822	iron-sulfur transferase activity
BF89_3022	COG0719	Fe-S assembly protein
BF89_3024	COG1695	Transcriptional regulator
BF89_3025	COG0737	Belongs to the 5'-nucleotidase family
BF89_3026	COG3377	Domain of unknown function (DUF1805)
BF89_3028	COG0739	heme binding
BF89_3033	COG4377	Putative membrane peptidase family (DUF2324)
BF89_3034	COG0789	Transcriptional regulator
BF89_3036	COG4470	Protein conserved in bacteria
BF89_3039	COG1494	fructose-1,6-bisphosphatase
BF89_3040	COG2445	Protein of unknown function DUF86
BF89_3042	COG0647	UMP catabolic process
BF89_3043	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_3045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF89_3046	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_3048	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF89_3049	COG4837	Protein of unknown function (DUF1462)
BF89_3057	COG2824	Alkylphosphonate utilization operon protein PhnA
BF89_3058	COG0390	transport system, permease component
BF89_3059	COG2274	protein secretion by the type I secretion system
BF89_306	COG0546	phosphoglycolate phosphatase activity
BF89_3060	COG1252	NADH dehydrogenase
BF89_3063	COG0316	Belongs to the HesB IscA family
BF89_3066	COG1683	Conserved Protein
BF89_3069	COG3708	Transcriptional regulator
BF89_3072	COG1252	NADH dehydrogenase
BF89_3075	COG3584	3D domain protein
BF89_3078	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF89_3079	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF89_308	COG4473	ABC transporter
BF89_3081	COG1268	BioY protein
BF89_3083	COG2050	protein possibly involved in aromatic compounds catabolism
BF89_3084	COG0423	glycine-tRNA ligase activity
BF89_3087	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_3088	COG5018	Exonuclease
BF89_309	COG1131	(ABC) transporter
BF89_3092	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF89_3094	COG2267	carboxylic ester hydrolase activity
BF89_3095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF89_3096	COG1522	sequence-specific DNA binding
BF89_3097	COG0436	Aminotransferase
BF89_3098	COG1098	S1 RNA binding domain
BF89_3099	COG2155	Conserved Protein
BF89_31	COG0457	Tetratricopeptide repeat
BF89_3100	COG0166	Belongs to the GPI family
BF89_3101	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF89_3103	COG1285	pathogenesis
BF89_311	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF89_3111	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF89_313	COG0456	acetyltransferase
BF89_3130	COG0039	L-malate dehydrogenase activity
BF89_3132	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF89_3133	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF89_3134	COG0297	glycogen (starch) synthase activity
BF89_3135	COG0058	SHG alpha-glucan phosphorylase activity
BF89_3139	COG1278	Cold shock
BF89_3140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF89_3141	COG1575	Belongs to the MenA family. Type 1 subfamily
BF89_3142	COG1169	isochorismate synthase
BF89_3143	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF89_3144	COG0596	Alpha beta hydrolase
BF89_3145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF89_3147	COG4948	Mandelate Racemase Muconate Lactonizing
BF89_315	COG1794	racemase activity, acting on amino acids and derivatives
BF89_3153	COG3964	amidohydrolase
BF89_316	COG1454	alcohol dehydrogenase
BF89_3160	COG0577	efflux transmembrane transporter activity
BF89_3161	COG0577	efflux transmembrane transporter activity
BF89_3162	COG1136	(ABC) transporter
BF89_3163	COG0577	efflux transmembrane transporter activity
BF89_3164	COG0577	efflux transmembrane transporter activity
BF89_3165	COG2205	protein histidine kinase activity
BF89_3166	COG0745	RESPONSE REGULATOR receiver
BF89_3167	COG2207	Transcriptional regulator
BF89_3167	COG3708	Transcriptional regulator
BF89_3168	COG1136	(ABC) transporter
BF89_3169	COG0577	efflux transmembrane transporter activity
BF89_317	COG2610	gluconate transmembrane transporter activity
BF89_3171	COG0586	Pfam SNARE associated Golgi protein
BF89_3178	COG1597	lipid kinase activity
BF89_3184	COG0745	RESPONSE REGULATOR receiver
BF89_3185	COG5002	protein histidine kinase activity
BF89_3192	COG1842	Phage shock protein A
BF89_3197	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_3201	COG1294	oxidase, subunit
BF89_3202	COG1271	oxidase subunit
BF89_3204	COG0288	reversible hydration of carbon dioxide
BF89_3209	COG0494	nUDIX hydrolase
BF89_3211	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF89_3215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_3216	COG1116	anion transmembrane transporter activity
BF89_3217	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_322	COG0733	neurotransmitter:sodium symporter activity
BF89_3221	COG1368	sulfuric ester hydrolase activity
BF89_3222	COG2267	carboxylic ester hydrolase activity
BF89_3223	COG4191	Histidine kinase
BF89_3224	COG5002	protein histidine kinase activity
BF89_3225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF89_3235	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF89_3237	COG0438	transferase activity, transferring glycosyl groups
BF89_3238	COG0671	phosphoesterase, PA-phosphatase related
BF89_3239	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF89_3240	COG2267	carboxylic ester hydrolase activity
BF89_3244	COG1794	racemase activity, acting on amino acids and derivatives
BF89_3246	COG1131	(ABC) transporter
BF89_3247	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF89_3248	COG1242	4 iron, 4 sulfur cluster binding
BF89_325	COG3850	Histidine kinase
BF89_325	COG5002	protein histidine kinase activity
BF89_3252	COG1136	(ABC) transporter
BF89_3254	COG0582	viral genome integration into host DNA
BF89_3255	COG0490	domain, Protein
BF89_3256	COG0475	glutathione-regulated potassium exporter activity
BF89_3257	COG2814	Major facilitator Superfamily
BF89_326	COG0745	RESPONSE REGULATOR receiver
BF89_3266	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF89_3268	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_327	COG0471	metal ion transport
BF89_3272	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF89_3273	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_3275	COG0303	'Molybdopterin
BF89_3276	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF89_3277	COG0314	molybdopterin synthase activity
BF89_328	COG1929	Belongs to the glycerate kinase type-1 family
BF89_3280	COG4975	Glucose uptake
BF89_3282	COG1329	Transcriptional regulator
BF89_3286	COG3832	glyoxalase III activity
BF89_3288	COG2814	Major facilitator Superfamily
BF89_3289	COG2081	HI0933 family
BF89_3290	COG2244	polysaccharide biosynthetic process
BF89_3291	COG1187	pseudouridine synthase activity
BF89_3292	COG1349	DNA-binding transcription factor activity
BF89_3293	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_3295	COG1523	belongs to the glycosyl hydrolase 13 family
BF89_3296	COG0510	thiamine kinase activity
BF89_3299	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_33	COG0737	Belongs to the 5'-nucleotidase family
BF89_3301	COG1363	Peptidase, m42
BF89_3302	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF89_3303	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_3304	COG4848	Belongs to the UPF0354 family
BF89_3305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_3307	COG1674	ftsk spoiiie
BF89_3310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_3314	COG2309	aminopeptidase activity
BF89_3316	COG3118	belongs to the thioredoxin family
BF89_3317	COG4851	CamS sex pheromone cAM373 precursor
BF89_3318	COG1609	Transcriptional regulator
BF89_3325	COG0666	response to abiotic stimulus
BF89_3327	COG0745	RESPONSE REGULATOR receiver
BF89_3329	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF89_3330	COG0517	IMP dehydrogenase activity
BF89_3331	COG0454	-acetyltransferase
BF89_3332	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF89_3334	COG1595	DNA-templated transcription, initiation
BF89_3336	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF89_3340	COG0626	cystathionine gamma-synthase activity
BF89_3341	COG1956	GAF domain-containing protein
BF89_3342	COG1309	transcriptional regulator
BF89_3343	COG1309	transcriptional regulator
BF89_3344	COG0697	spore germination
BF89_3345	COG0583	DNA-binding transcription factor activity
BF89_3347	COG1104	cysteine desulfurase activity
BF89_3350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF89_3352	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF89_3353	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF89_3355	COG3874	Sporulation protein YtfJ
BF89_3356	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF89_3357	COG0827	DNA restriction-modification system
BF89_3358	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF89_3362	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_3370	COG0589	response to stress
BF89_3371	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_3374	COG1476	TRANSCRIPTIONal
BF89_3376	COG0662	Cupin 2, conserved barrel domain protein
BF89_3377	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_3384	COG0006	proline dipeptidase activity
BF89_3387	COG4109	DRTGG domain
BF89_3391	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF89_3394	COG0587	DNA-directed DNA polymerase activity
BF89_3395	COG0281	malic enzyme
BF89_3396	COG1725	Transcriptional regulator
BF89_3401	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF89_3402	COG0628	permease
BF89_3404	COG0372	Belongs to the citrate synthase family
BF89_3405	COG0538	isocitrate dehydrogenase activity
BF89_3409	COG0745	RESPONSE REGULATOR receiver
BF89_3410	COG5002	protein histidine kinase activity
BF89_3411	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_3411	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_3412	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF89_3413	COG1971	Probably functions as a manganese efflux pump
BF89_3414	COG0237	dephospho-CoA kinase activity
BF89_3415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF89_3416	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF89_3418	COG3611	Membrane attachment protein
BF89_3419	COG1484	DNA-dependent DNA replication
BF89_3421	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_3422	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF89_3426	COG1363	Peptidase, m42
BF89_3427	COG1309	transcriptional regulator
BF89_3428	COG1566	PFAM secretion protein HlyD family protein
BF89_3429	COG2814	Major facilitator Superfamily
BF89_3434	COG1418	mRNA catabolic process
BF89_3436	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF89_3438	COG0072	phenylalanine-tRNA ligase activity
BF89_3438	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_3439	COG0017	Asparaginyl-tRNA synthetase
BF89_3445	COG1286	toxin biosynthetic process
BF89_3446	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF89_3446	COG1796	DNA polymerase
BF89_3449	COG1187	pseudouridine synthase activity
BF89_3450	COG1114	Component of the transport system for branched-chain amino acids
BF89_3451	COG5386	Cell surface protein
BF89_3453	COG5386	Cell surface protein
BF89_3456	COG1120	ATPase activity
BF89_3457	COG4509	Sortase family
BF89_346	COG1674	ftsk spoiiie
BF89_3460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF89_3461	COG4895	conserved protein (DUF2196)
BF89_3463	COG0745	RESPONSE REGULATOR receiver
BF89_3464	COG2205	protein histidine kinase activity
BF89_3465	COG1131	(ABC) transporter
BF89_3471	COG2318	DinB family
BF89_3475	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_3476	COG1309	transcriptional regulator
BF89_3477	COG1024	Enoyl-CoA hydratase
BF89_3478	COG2086	electron transfer activity
BF89_3479	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF89_3480	COG3118	belongs to the thioredoxin family
BF89_3482	COG1719	4-vinyl reductase, 4VR
BF89_3483	COG2009	succinate dehydrogenase
BF89_3484	COG1053	succinate dehydrogenase
BF89_3485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF89_3486	COG0824	Thioesterase
BF89_3487	COG1876	peptidase activity
BF89_3488	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF89_3489	COG1360	Flagellar Motor Protein
BF89_3490	COG1360	Flagellar Motor Protein
BF89_3491	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF89_3492	COG4152	abc transporter atp-binding protein
BF89_3493	COG1668	transmembrane transport
BF89_3494	COG1959	2 iron, 2 sulfur cluster binding
BF89_3496	COG0697	spore germination
BF89_3497	COG1396	sequence-specific DNA binding
BF89_3498	COG1983	PspC domain protein
BF89_350	COG0017	Asparaginyl-tRNA synthetase
BF89_3501	COG3279	Response regulator of the LytR AlgR family
BF89_3502	COG3275	phosphorelay sensor kinase activity
BF89_3503	COG4608	Belongs to the ABC transporter superfamily
BF89_3504	COG0444	Belongs to the ABC transporter superfamily
BF89_3508	COG0402	S-adenosylhomocysteine deaminase activity
BF89_3509	COG0402	S-adenosylhomocysteine deaminase activity
BF89_351	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF89_3511	COG2233	PERMEase
BF89_3512	COG2197	response regulator
BF89_3515	COG1309	transcriptional regulator
BF89_3519	COG5401	PFAM Sporulation and spore germination
BF89_3521	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF89_3522	COG0622	Phosphoesterase
BF89_3532	COG0470	DNA polymerase III
BF89_3532	COG1067	ATP-dependent peptidase activity
BF89_3535	COG1764	response to oxidative stress
BF89_3536	COG1846	Transcriptional regulator
BF89_3538	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF89_354	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF89_3540	COG1587	Uroporphyrinogen-III synthase
BF89_3541	COG0113	porphobilinogen synthase activity
BF89_3543	COG1388	LysM domain
BF89_3545	COG0525	valine-tRNA ligase activity
BF89_3546	COG0285	dihydrofolate synthase activity
BF89_3550	COG1077	Cell shape determining protein MreB Mrl
BF89_3551	COG1792	Involved in formation and maintenance of cell shape
BF89_3554	COG2894	cell division
BF89_3555	COG0739	heme binding
BF89_3556	COG1994	Peptidase M50
BF89_3557	COG1530	ribonuclease E activity
BF89_3559	COG2868	ribosomal protein
BF89_3561	COG3290	protein histidine kinase activity
BF89_3562	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF89_3563	COG0745	RESPONSE REGULATOR receiver
BF89_3565	COG5002	protein histidine kinase activity
BF89_3566	COG1136	(ABC) transporter
BF89_3567	COG0577	efflux transmembrane transporter activity
BF89_3568	COG0577	efflux transmembrane transporter activity
BF89_3569	COG0077	Prephenate dehydratase
BF89_3570	COG2258	MOSC domain
BF89_3571	COG1827	regulation of RNA biosynthetic process
BF89_3572	COG1104	cysteine desulfurase activity
BF89_3573	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF89_3574	COG0157	Belongs to the NadC ModD family
BF89_3579	COG0640	Transcriptional regulator
BF89_3580	COG0697	spore germination
BF89_3581	COG0697	spore germination
BF89_3583	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF89_3589	COG1862	Preprotein translocase
BF89_3591	COG2323	membrane
BF89_3592	COG2244	polysaccharide biosynthetic process
BF89_3594	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF89_3594	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF89_3595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF89_3596	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF89_3596	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF89_3598	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF89_360	COG0018	arginyl-trna synthetase
BF89_3601	COG0124	histidyl-tRNA synthetase
BF89_3603	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF89_3605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF89_3606	COG1959	2 iron, 2 sulfur cluster binding
BF89_3607	COG1104	cysteine desulfurase activity
BF89_3608	COG0482	sulfurtransferase activity
BF89_361	COG2521	methyltransferase
BF89_361	COG2136	Putative SAM-dependent methyltransferase
BF89_3610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF89_3614	COG0628	permease
BF89_3616	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_3620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF89_3626	COG0768	penicillin binding
BF89_3631	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_3632	COG0626	cystathionine gamma-synthase activity
BF89_3633	COG1012	belongs to the aldehyde dehydrogenase family
BF89_3633	COG1454	alcohol dehydrogenase
BF89_3635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_364	COG1413	lyase activity
BF89_3643	COG2259	Doxx family
BF89_3644	COG2514	catechol 2,3-dioxygenase activity
BF89_3646	COG3186	Phenylalanine-4-hydroxylase
BF89_3647	COG1404	Belongs to the peptidase S8 family
BF89_365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF89_3654	COG2267	carboxylic ester hydrolase activity
BF89_3656	COG1785	Belongs to the alkaline phosphatase family
BF89_3658	COG2357	RelA SpoT domain protein
BF89_3659	COG0778	Nitroreductase
BF89_3661	COG1595	DNA-templated transcription, initiation
BF89_3663	COG1191	sigma factor activity
BF89_3665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF89_3666	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF89_3668	COG1534	Rna-binding protein
BF89_367	COG0629	single-stranded DNA binding
BF89_3670	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF89_3671	COG0799	negative regulation of ribosome biogenesis
BF89_3672	COG2226	methyltransferase
BF89_3673	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_3674	COG1596	polysaccharide export
BF89_3674	COG1555	photosystem II stabilization
BF89_3675	COG2131	deaminase
BF89_3676	COG2333	competence protein COMEC
BF89_3676	COG0658	competence protein
BF89_3678	COG1466	dna polymerase III delta subunit
BF89_3683	COG1733	regulation of RNA biosynthetic process
BF89_3684	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF89_3686	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF89_3690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF89_3691	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF89_3693	COG1610	YqeY-like protein
BF89_3696	COG1702	phosphate starvation-inducible protein PhoH
BF89_3697	COG1480	7TM receptor with intracellular HD hydrolase
BF89_3699	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF89_370	COG0488	(ABC) transporter
BF89_3700	COG0295	cytidine deaminase activity
BF89_3701	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF89_3704	COG0517	IMP dehydrogenase activity
BF89_3706	COG0358	DNA primase activity
BF89_3707	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF89_3708	COG2010	Cytochrome c
BF89_3709	COG2384	SAM-dependent methyltransferase
BF89_371	COG1418	mRNA catabolic process
BF89_3710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF89_3716	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_3717	COG1121	(ABC) transporter
BF89_3718	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF89_3719	COG0735	belongs to the Fur family
BF89_3724	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_3725	COG0477	Major facilitator Superfamily
BF89_3727	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF89_3728	COG0573	inorganic phosphate transmembrane transporter activity
BF89_3729	COG0581	inorganic phosphate transmembrane transporter activity
BF89_3730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF89_3731	COG0704	Plays a role in the regulation of phosphate uptake
BF89_3732	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF89_3734	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF89_3735	COG4483	Protein conserved in bacteria
BF89_3736	COG1940	carbohydrate kinase activity
BF89_3738	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_374	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_3742	COG0626	cystathionine gamma-synthase activity
BF89_3743	COG0626	cystathionine gamma-synthase activity
BF89_3744	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF89_3744	COG0646	methionine synthase
BF89_3745	COG0646	methionine synthase
BF89_3745	COG1410	methionine synthase
BF89_3746	COG1410	methionine synthase
BF89_3746	COG0646	methionine synthase
BF89_3747	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF89_3757	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF89_3758	COG1459	type II secretion system
BF89_3759	COG4537	Required for transformation and DNA binding
BF89_3760	COG4970	Tfp pilus assembly protein FimT
BF89_377	COG2359	stage V sporulation protein S
BF89_3771	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_3777	COG1725	Transcriptional regulator
BF89_3778	COG1131	(ABC) transporter
BF89_3785	COG2076	Multidrug Resistance protein
BF89_3786	COG2076	Multidrug Resistance protein
BF89_3788	COG1609	Transcriptional regulator
BF89_3789	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_3790	COG0095	Lipoate-protein ligase
BF89_3795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF89_3796	COG3872	metal-dependent enzyme
BF89_3799	COG0006	proline dipeptidase activity
BF89_3804	COG3854	ATPases associated with a variety of cellular activities
BF89_3813	COG0511	ligase activity, forming carbon-carbon bonds
BF89_3814	COG0439	Biotin carboxylase
BF89_3815	COG1302	Protein conserved in bacteria
BF89_3820	COG0142	geranyltranstransferase activity
BF89_3822	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF89_3824	COG0497	DNA recombination
BF89_3825	COG0750	zinc metalloprotease
BF89_3826	COG0745	RESPONSE REGULATOR receiver
BF89_3828	COG3093	addiction module antidote protein HigA
BF89_3829	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_3831	COG3290	protein histidine kinase activity
BF89_3831	COG3829	transcription factor binding
BF89_3832	COG0280	phosphate acetyltransferase
BF89_3833	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF89_3835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF89_3836	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_3837	COG0022	dehydrogenase e1 component
BF89_3838	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_3839	COG0772	Belongs to the SEDS family
BF89_3840	COG2816	NAD+ diphosphatase activity
BF89_3843	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_3844	COG0765	amino acid transport
BF89_3845	COG1126	abc transporter atp-binding protein
BF89_3846	COG4129	membrane
BF89_3847	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_3849	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_385	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF89_3850	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF89_3852	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF89_3855	COG1760	l-serine dehydratase
BF89_3856	COG1760	l-serine dehydratase
BF89_3857	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_3858	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_3859	COG0300	oxidoreductase activity
BF89_386	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF89_3862	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF89_3864	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF89_3868	COG1522	sequence-specific DNA binding
BF89_387	COG2146	nitrite reductase [NAD(P)H] activity
BF89_3870	COG0737	Belongs to the 5'-nucleotidase family
BF89_3873	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_3875	COG0156	8-amino-7-oxononanoate synthase activity
BF89_3876	COG1073	alpha beta
BF89_3876	COG2226	methyltransferase
BF89_3877	COG4106	trans-aconitate 2-methyltransferase activity
BF89_3878	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF89_388	COG1587	Uroporphyrinogen-III synthase
BF89_388	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF89_3882	COG0307	riboflavin synthase, alpha
BF89_3883	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF89_3883	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF89_3886	COG1073	alpha beta
BF89_3887	COG0456	acetyltransferase
BF89_3888	COG1609	Transcriptional regulator
BF89_3889	COG2056	Na+-H+ antiporter family
BF89_3890	COG0596	Alpha beta hydrolase
BF89_3892	COG1525	nuclease
BF89_3892	COG0737	Belongs to the 5'-nucleotidase family
BF89_3892	COG4085	toxin activity
BF89_3894	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_3894	COG0456	acetyltransferase
BF89_3895	COG0656	L-ascorbic acid biosynthetic process
BF89_3896	COG0667	Aldo Keto reductase
BF89_390	COG1648	precorrin-2 dehydrogenase activity
BF89_3900	COG1300	Membrane
BF89_3901	COG0735	belongs to the Fur family
BF89_3903	COG4974	Belongs to the 'phage' integrase family
BF89_3908	COG0598	Magnesium transport protein CorA
BF89_3911	COG1846	Transcriptional regulator
BF89_3914	COG1131	(ABC) transporter
BF89_3915	COG1725	Transcriptional regulator
BF89_3916	COG1686	Belongs to the peptidase S11 family
BF89_3920	COG0733	neurotransmitter:sodium symporter activity
BF89_3925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_3928	COG0697	spore germination
BF89_3929	COG0561	phosphatase activity
BF89_393	COG2223	nitrite transmembrane transporter activity
BF89_3930	COG4086	secreted protein
BF89_3931	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF89_3932	COG0456	acetyltransferase
BF89_3933	COG1547	Domain of unknown function (DUF309)
BF89_3938	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF89_3942	COG3711	transcriptional antiterminator
BF89_3943	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_3943	COG2190	(PTS) system
BF89_3943	COG1263	PTS System
BF89_3948	COG0778	Nitroreductase
BF89_3949	COG3706	GGDEF domain
BF89_395	COG0314	molybdopterin synthase activity
BF89_3950	COG2084	Dehydrogenase
BF89_3951	COG2084	Dehydrogenase
BF89_3954	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF89_3958	COG0436	Aminotransferase
BF89_3959	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF89_396	COG0303	'Molybdopterin
BF89_3963	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_3964	COG1695	Transcriptional regulator
BF89_397	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_3971	COG0183	Belongs to the thiolase family
BF89_3979	COG3842	ATPase activity
BF89_398	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF89_3980	COG0366	Alpha amylase catalytic
BF89_3982	COG2182	Extracellular solute-binding protein
BF89_3983	COG1175	transmembrane transport
BF89_3984	COG3833	ABC-type maltose transport systems, permease component
BF89_3985	COG1609	Transcriptional regulator
BF89_3986	COG0436	Aminotransferase
BF89_3988	COG2205	protein histidine kinase activity
BF89_399	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF89_3990	COG3209	COG3209 Rhs family protein
BF89_3994	COG2814	Major facilitator Superfamily
BF89_4	COG0511	ligase activity, forming carbon-carbon bonds
BF89_4001	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF89_4002	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF89_4004	COG1408	metallophosphoesterase
BF89_4005	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4006	COG2200	EAL domain
BF89_4009	COG4703	Protein of unknown function (DUF1797)
BF89_4011	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF89_4013	COG0517	IMP dehydrogenase activity
BF89_4014	COG0583	DNA-binding transcription factor activity
BF89_4018	COG0569	domain protein
BF89_4019	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_4021	COG0561	phosphatase activity
BF89_4022	COG0242	peptide deformylase activity
BF89_4024	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_4025	COG0022	dehydrogenase e1 component
BF89_403	COG2181	nitrate reductase activity
BF89_4035	COG1982	Orn Lys Arg decarboxylase major
BF89_4039	COG0483	inositol monophosphate 1-phosphatase activity
BF89_404	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF89_4044	COG4896	Protein conserved in bacteria
BF89_4046	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF89_4047	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF89_4048	COG4838	Belongs to the UPF0358 family
BF89_4049	COG0772	Belongs to the SEDS family
BF89_405	COG1140	nitrate reductase beta subunit
BF89_4050	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF89_4057	COG3336	cytochrome c oxidase
BF89_406	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF89_4060	COG2340	Cysteine-rich secretory protein family
BF89_4063	COG0406	alpha-ribazole phosphatase activity
BF89_4064	COG3679	Belongs to the UPF0342 family
BF89_4068	COG0742	ribosomal rna small subunit methyltransferase
BF89_4069	COG3314	Sporulation integral membrane protein YlbJ
BF89_4071	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF89_4072	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF89_4074	COG0582	viral genome integration into host DNA
BF89_4078	COG1396	sequence-specific DNA binding
BF89_4082	COG1396	sequence-specific DNA binding
BF89_4087	COG1484	DNA-dependent DNA replication
BF89_409	COG0714	Associated with various cellular activities
BF89_4092	COG1191	sigma factor activity
BF89_410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF89_4108	COG0582	viral genome integration into host DNA
BF89_411	COG1305	Transglutaminase-like
BF89_4113	COG4626	Terminase
BF89_4113	COG1802	Transcriptional regulator
BF89_412	COG0386	Belongs to the glutathione peroxidase family
BF89_4132	COG4824	toxin secretion phage lysis holin
BF89_4143	COG1399	metal-binding, possibly nucleic acid-binding protein
BF89_4147	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF89_4150	COG4839	cell division protein FtsL
BF89_4152	COG0768	penicillin binding
BF89_4153	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_4156	COG0772	Belongs to the SEDS family
BF89_4157	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF89_4158	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF89_4159	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF89_4160	COG0849	cell division
BF89_4161	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF89_4163	COG1191	sigma factor activity
BF89_4164	COG1191	sigma factor activity
BF89_4165	COG1873	PFAM PRC-barrel domain
BF89_4167	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF89_4169	COG0762	integral membrane protein
BF89_417	COG1595	DNA-templated transcription, initiation
BF89_4170	COG2302	S4 RNA-binding domain
BF89_4171	COG3599	regulation of cell shape
BF89_4172	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF89_4175	COG0564	pseudouridine synthase activity
BF89_418	COG0604	alcohol dehydrogenase
BF89_4180	COG0505	Belongs to the CarA family
BF89_4188	COG3069	C4-dicarboxylate transmembrane transporter activity
BF89_4191	COG0006	proline dipeptidase activity
BF89_4193	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF89_4194	COG1561	YicC-like family, N-terminal region
BF89_4196	COG0194	GDP metabolic process
BF89_4198	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF89_4199	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF89_42	COG1012	belongs to the aldehyde dehydrogenase family
BF89_420	COG0346	lactoylglutathione lyase activity
BF89_4200	COG0242	peptide deformylase activity
BF89_4202	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF89_4202	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF89_4204	COG0631	protein serine/threonine phosphatase activity
BF89_4205	COG0515	serine threonine protein kinase
BF89_4205	COG2815	serine threonine protein kinase
BF89_4206	COG1162	GTPase activity
BF89_4207	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF89_4208	COG1564	THIamine pyrophosphokinase
BF89_421	COG1082	Xylose isomerase domain protein TIM barrel
BF89_4210	COG1302	Protein conserved in bacteria
BF89_4211	COG1461	Dihydroxyacetone kinase
BF89_4212	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF89_4215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF89_4216	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4219	COG1196	nuclear chromosome segregation
BF89_4220	COG0552	protein localization to endoplasmic reticulum
BF89_4222	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF89_4224	COG1837	Belongs to the UPF0109 family
BF89_4232	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF89_4235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF89_4237	COG4974	Belongs to the 'phage' integrase family
BF89_4243	COG0528	UMP kinase activity
BF89_4246	COG4589	Belongs to the CDS family
BF89_4247	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF89_4248	COG0750	zinc metalloprotease
BF89_4252	COG0195	Participates in both transcription termination and antitermination
BF89_4253	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF89_4254	COG1358	cellular component organization or biogenesis
BF89_4256	COG1550	Protein conserved in bacteria
BF89_4258	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF89_4259	COG0196	riboflavin kinase activity
BF89_426	COG2226	methyltransferase
BF89_4262	COG0726	polysaccharide deacetylase
BF89_4263	COG0612	Peptidase, M16
BF89_4264	COG1873	PFAM PRC-barrel domain
BF89_4265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF89_4266	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF89_4267	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF89_4268	COG0527	aspartate kinase activity
BF89_4270	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_4271	COG0740	serine-type endopeptidase activity
BF89_4273	COG1674	ftsk spoiiie
BF89_4274	COG2188	Transcriptional regulator
BF89_4280	COG0612	Peptidase, M16
BF89_4281	COG0612	Peptidase, M16
BF89_4282	COG0300	oxidoreductase activity
BF89_4285	COG1426	Protein conserved in bacteria
BF89_4286	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF89_4291	COG1692	metallophosphoesterase
BF89_4292	COG2359	stage V sporulation protein S
BF89_4294	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF89_4294	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF89_4295	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF89_4296	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF89_4297	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF89_4306	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF89_4308	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_4309	COG1368	sulfuric ester hydrolase activity
BF89_431	COG3874	Sporulation protein YtfJ
BF89_4310	COG0562	UDP-galactopyranose mutase
BF89_4311	COG3773	Cell wall hydrolase
BF89_4312	COG1404	Belongs to the peptidase S8 family
BF89_4315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_4316	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_4316	COG0596	Alpha beta hydrolase
BF89_4317	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_4318	COG1380	Effector of murein hydrolase LrgA
BF89_4319	COG1346	cytolysis
BF89_4323	COG3300	MHYT domain
BF89_4323	COG5001	Diguanylate cyclase
BF89_4324	COG0346	lactoylglutathione lyase activity
BF89_4325	COG2267	carboxylic ester hydrolase activity
BF89_4328	COG2364	Membrane
BF89_4330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF89_4331	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF89_4332	COG2169	Transcriptional regulator
BF89_4333	COG0708	Exodeoxyribonuclease III
BF89_4334	COG0708	Exodeoxyribonuclease III
BF89_4336	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_4337	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_4338	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_4339	COG1120	ATPase activity
BF89_4340	COG2819	hydrolase of the alpha beta superfamily
BF89_4342	COG1937	Protein conserved in bacteria
BF89_4343	COG2608	mercury ion transmembrane transporter activity
BF89_4344	COG2217	Heavy metal translocating P-type atpase
BF89_4346	COG2116	formate transmembrane transporter activity
BF89_4347	COG1408	metallophosphoesterase
BF89_4350	COG1113	amino acid transport
BF89_4353	COG2322	membrane
BF89_4354	COG1979	alcohol dehydrogenase
BF89_4355	COG1979	alcohol dehydrogenase
BF89_4356	COG1349	DNA-binding transcription factor activity
BF89_4357	COG1105	Belongs to the carbohydrate kinase PfkB family
BF89_4358	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_4358	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF89_4358	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF89_4359	COG3584	3D domain protein
BF89_4359	COG1388	LysM domain
BF89_4365	COG0464	growth
BF89_4367	COG2860	membrane
BF89_4368	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF89_4369	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF89_4370	COG0789	Transcriptional regulator
BF89_4371	COG0174	glutamine synthetase
BF89_4376	COG1396	sequence-specific DNA binding
BF89_4392	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF89_44	COG0673	inositol 2-dehydrogenase activity
BF89_440	COG0456	acetyltransferase
BF89_4400	COG1595	DNA-templated transcription, initiation
BF89_4431	COG4824	toxin secretion phage lysis holin
BF89_4432	COG1388	LysM domain
BF89_4432	COG3409	Peptidoglycan-binding domain 1 protein
BF89_4432	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_4440	COG1695	Transcriptional regulator
BF89_4444	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF89_4446	COG0737	Belongs to the 5'-nucleotidase family
BF89_4449	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF89_4450	COG3639	organic phosphonate transmembrane transporter activity
BF89_4456	COG1132	(ABC) transporter
BF89_4457	COG1132	(ABC) transporter
BF89_446	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_4460	COG3409	Peptidoglycan-binding domain 1 protein
BF89_4460	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_4462	COG0730	response to heat
BF89_4466	COG1346	cytolysis
BF89_4467	COG1380	Effector of murein hydrolase LrgA
BF89_4468	COG0583	DNA-binding transcription factor activity
BF89_447	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_4470	COG0785	Cytochrome C biogenesis protein
BF89_4471	COG4846	Membrane protein involved in cytochrome C biogenesis
BF89_448	COG1819	glycosyl
BF89_4481	COG2226	methyltransferase
BF89_4486	COG0010	Belongs to the arginase family
BF89_4487	COG1329	Transcriptional regulator
BF89_4488	COG1902	pentaerythritol trinitrate reductase activity
BF89_4489	COG0069	glutamate synthase activity
BF89_4490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_4491	COG0346	lactoylglutathione lyase activity
BF89_4492	COG0400	carboxylic ester hydrolase activity
BF89_4493	COG5002	protein histidine kinase activity
BF89_4495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_45	COG2814	Major facilitator Superfamily
BF89_4504	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_4505	COG1268	BioY protein
BF89_4506	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_4507	COG0183	Belongs to the thiolase family
BF89_4510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_4512	COG2211	Major facilitator Superfamily
BF89_4515	COG0726	polysaccharide deacetylase
BF89_4517	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF89_4518	COG2274	protein secretion by the type I secretion system
BF89_452	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF89_4520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_4526	COG0824	Thioesterase
BF89_4527	COG4841	protein insertion into membrane
BF89_4528	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_4531	COG0745	RESPONSE REGULATOR receiver
BF89_4532	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_4533	COG1832	CoA-binding protein
BF89_4534	COG0187	DNA topoisomerase II activity
BF89_4535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF89_4536	COG0673	inositol 2-dehydrogenase activity
BF89_4538	COG1131	(ABC) transporter
BF89_454	COG0561	phosphatase activity
BF89_4542	COG1595	DNA-templated transcription, initiation
BF89_4544	COG1316	TRANSCRIPTIONal
BF89_4545	COG1301	dicarboxylic acid transport
BF89_4546	COG4166	transmembrane transport
BF89_4547	COG4166	transmembrane transport
BF89_4548	COG2226	methyltransferase
BF89_4556	COG0697	spore germination
BF89_4558	COG3383	formate dehydrogenase (NAD+) activity
BF89_4559	COG3383	formate dehydrogenase (NAD+) activity
BF89_4560	COG2427	Protein of unknown function (DUF1641)
BF89_4561	COG5609	conserved protein (DUF2294)
BF89_4562	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF89_4564	COG2116	formate transmembrane transporter activity
BF89_4565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_4566	COG0303	'Molybdopterin
BF89_4567	COG0314	molybdopterin synthase activity
BF89_4569	COG0489	protein tyrosine kinase activity
BF89_4572	COG3326	Membrane
BF89_4573	COG2962	Rard protein
BF89_4574	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF89_4575	COG1657	PFAM Prenyltransferase squalene oxidase
BF89_4577	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4578	COG1012	belongs to the aldehyde dehydrogenase family
BF89_458	COG2211	Major facilitator Superfamily
BF89_4580	COG4145	pantothenate transmembrane transporter activity
BF89_4584	COG0165	Argininosuccinate lyase
BF89_4586	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_459	COG0154	amidase activity
BF89_4592	COG0716	FMN binding
BF89_4594	COG1278	Cold shock
BF89_46	COG1609	Transcriptional regulator
BF89_4600	COG2720	vancomycin resistance protein
BF89_4601	COG2514	catechol 2,3-dioxygenase activity
BF89_4603	COG1285	pathogenesis
BF89_4605	COG1024	Enoyl-CoA hydratase
BF89_4606	COG1216	Glycosyl transferase, family 2
BF89_461	COG1876	peptidase activity
BF89_4612	COG0277	FAD linked oxidase domain protein
BF89_4613	COG0385	Bile acid
BF89_4615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_4617	COG2808	Putative FMN-binding domain
BF89_4620	COG0457	Tetratricopeptide repeat
BF89_4622	COG0604	alcohol dehydrogenase
BF89_4623	COG0640	Transcriptional regulator
BF89_4627	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_463	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_4633	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_4634	COG1164	Oligoendopeptidase f
BF89_4635	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF89_4639	COG1193	negative regulation of DNA recombination
BF89_4643	COG0583	DNA-binding transcription factor activity
BF89_4649	COG0384	phenazine biosynthesis protein PhzF
BF89_4650	COG3739	integral membrane protein
BF89_4651	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_4652	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_4654	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_4658	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_4659	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_4665	COG2814	Major facilitator Superfamily
BF89_4666	COG1113	amino acid transport
BF89_4667	COG0604	alcohol dehydrogenase
BF89_467	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_4674	COG2072	flavoprotein involved in K transport
BF89_468	COG1114	Component of the transport system for branched-chain amino acids
BF89_4681	COG3757	hydrolase, family 25
BF89_4681	COG3409	Peptidoglycan-binding domain 1 protein
BF89_4682	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_4686	COG1151	hydroxylamine reductase activity
BF89_4691	COG3152	Membrane
BF89_4695	COG1309	transcriptional regulator
BF89_4698	COG1191	sigma factor activity
BF89_47	COG0671	phosphoesterase, PA-phosphatase related
BF89_4701	COG0726	polysaccharide deacetylase
BF89_4705	COG1733	regulation of RNA biosynthetic process
BF89_4706	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_4708	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_471	COG1253	flavin adenine dinucleotide binding
BF89_4710	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4712	COG0384	phenazine biosynthesis protein PhzF
BF89_4716	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_4719	COG1733	regulation of RNA biosynthetic process
BF89_472	COG2839	Protein conserved in bacteria
BF89_4720	COG1733	regulation of RNA biosynthetic process
BF89_4721	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF89_4722	COG0673	inositol 2-dehydrogenase activity
BF89_4723	COG2188	Transcriptional regulator
BF89_4724	COG1733	regulation of RNA biosynthetic process
BF89_4725	COG1393	Belongs to the ArsC family
BF89_473	COG0702	epimerase
BF89_4730	COG0814	amino acid
BF89_4731	COG0346	lactoylglutathione lyase activity
BF89_4734	COG2814	Major facilitator Superfamily
BF89_4735	COG0656	L-ascorbic acid biosynthetic process
BF89_4740	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4743	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_4744	COG0604	alcohol dehydrogenase
BF89_4745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF89_4746	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF89_4748	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF89_4749	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF89_4751	COG1070	Carbohydrate kinase
BF89_4752	COG2706	6-phosphogluconolactonase activity
BF89_4753	COG3813	Protein conserved in bacteria
BF89_4754	COG1357	PFAM Pentapeptide repeats (8 copies)
BF89_4755	COG0697	spore germination
BF89_4756	COG0789	Transcriptional regulator
BF89_4757	COG1253	flavin adenine dinucleotide binding
BF89_476	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_4764	COG0477	Major facilitator Superfamily
BF89_4766	COG2226	methyltransferase
BF89_477	COG1607	acyl-coa hydrolase
BF89_4770	COG0628	permease
BF89_4771	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF89_4772	COG0180	Tryptophanyl-tRNA synthetase
BF89_4774	COG1136	(ABC) transporter
BF89_4776	COG0110	maltose O-acetyltransferase activity
BF89_4777	COG0738	Major facilitator superfamily
BF89_4778	COG1940	carbohydrate kinase activity
BF89_4779	COG0346	lactoylglutathione lyase activity
BF89_478	COG3689	TIGRFAM TIGR03943 family protein
BF89_4786	COG1011	Hydrolase
BF89_479	COG0701	Predicted permease
BF89_4791	COG1131	(ABC) transporter
BF89_4793	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_4797	COG0778	Nitroreductase
BF89_4798	COG1733	regulation of RNA biosynthetic process
BF89_48	COG2367	Beta-lactamase
BF89_4801	COG0124	histidyl-tRNA synthetase
BF89_4802	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF89_4803	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_4804	COG3620	sequence-specific DNA binding
BF89_4807	COG2356	endonuclease I
BF89_4808	COG1288	antiporter activity
BF89_4809	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF89_481	COG2244	polysaccharide biosynthetic process
BF89_4812	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF89_4813	COG1122	ATPase activity
BF89_482	COG0586	Pfam SNARE associated Golgi protein
BF89_4820	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_4822	COG2031	fatty acid transporter
BF89_4824	COG1309	transcriptional regulator
BF89_4825	COG2076	Multidrug Resistance protein
BF89_4829	COG1131	(ABC) transporter
BF89_483	COG1051	belongs to the nudix hydrolase family
BF89_4830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_4833	COG2814	Major facilitator Superfamily
BF89_4834	COG1846	Transcriptional regulator
BF89_4836	COG0477	Major facilitator Superfamily
BF89_484	COG5337	Spore coat protein CotH
BF89_4847	COG2207	Transcriptional regulator
BF89_4847	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_4848	COG0662	Cupin 2, conserved barrel domain protein
BF89_4851	COG1595	DNA-templated transcription, initiation
BF89_4855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF89_4858	COG0531	amino acid
BF89_4859	COG1522	sequence-specific DNA binding
BF89_486	COG0406	alpha-ribazole phosphatase activity
BF89_4863	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF89_4864	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF89_4865	COG1760	l-serine dehydratase
BF89_4866	COG1760	l-serine dehydratase
BF89_4867	COG0814	amino acid
BF89_4870	COG1309	transcriptional regulator
BF89_4871	COG2814	Major facilitator Superfamily
BF89_4872	COG2184	nucleotidyltransferase activity
BF89_4875	COG0534	Mate efflux family protein
BF89_4882	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF89_4886	COG0457	Tetratricopeptide repeat
BF89_4887	COG1609	Transcriptional regulator
BF89_4888	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF89_4889	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF89_489	COG4166	transmembrane transport
BF89_4890	COG0561	phosphatase activity
BF89_4891	COG0673	inositol 2-dehydrogenase activity
BF89_4892	COG0738	Major facilitator superfamily
BF89_4896	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_4898	COG0583	DNA-binding transcription factor activity
BF89_4900	COG1139	Iron-sulfur cluster binding protein
BF89_4901	COG1556	Lactate utilization protein
BF89_4902	COG2271	Major facilitator Superfamily
BF89_4903	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_4904	COG2808	Putative FMN-binding domain
BF89_4905	COG0456	acetyltransferase
BF89_4906	COG1846	Transcriptional regulator
BF89_4907	COG2364	Membrane
BF89_4909	COG3850	Histidine kinase
BF89_4909	COG5002	protein histidine kinase activity
BF89_491	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF89_4912	COG0577	efflux transmembrane transporter activity
BF89_4913	COG1136	(ABC) transporter
BF89_4916	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF89_4917	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_4919	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_4920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_4923	COG1476	TRANSCRIPTIONal
BF89_4929	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF89_493	COG0702	epimerase
BF89_4934	COG5002	protein histidine kinase activity
BF89_4934	COG3850	Histidine kinase
BF89_4935	COG0745	RESPONSE REGULATOR receiver
BF89_4940	COG2814	Major facilitator Superfamily
BF89_4947	COG2169	Transcriptional regulator
BF89_495	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF89_495	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF89_4951	COG0346	lactoylglutathione lyase activity
BF89_4954	COG1522	sequence-specific DNA binding
BF89_4957	COG0443	Heat shock 70 kDa protein
BF89_4961	COG0640	Transcriptional regulator
BF89_4962	COG0346	lactoylglutathione lyase activity
BF89_4963	COG0798	PFAM Bile acid sodium symporter
BF89_4969	COG1121	(ABC) transporter
BF89_4970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF89_4971	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF89_4972	COG2267	carboxylic ester hydrolase activity
BF89_4973	COG1575	Belongs to the MenA family. Type 1 subfamily
BF89_4975	COG5609	conserved protein (DUF2294)
BF89_4976	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF89_4978	COG0288	reversible hydration of carbon dioxide
BF89_4979	COG0415	Belongs to the DNA photolyase family
BF89_4986	COG0598	Magnesium transport protein CorA
BF89_4987	COG1846	Transcriptional regulator
BF89_4988	COG0583	DNA-binding transcription factor activity
BF89_4993	COG1335	isochorismatase
BF89_4994	COG2267	carboxylic ester hydrolase activity
BF89_4995	COG0753	catalase activity
BF89_4996	COG0737	Belongs to the 5'-nucleotidase family
BF89_5	COG0439	Biotin carboxylase
BF89_50	COG0768	penicillin binding
BF89_5002	COG1115	amino acid carrier protein
BF89_5004	COG2066	Belongs to the glutaminase family
BF89_5005	COG4191	Histidine kinase
BF89_5006	COG0784	Response regulator, receiver
BF89_5007	COG0697	spore germination
BF89_5008	COG0531	amino acid
BF89_5011	COG0281	malic enzyme
BF89_5013	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_5014	COG1114	Component of the transport system for branched-chain amino acids
BF89_5015	COG0531	amino acid
BF89_5016	COG0322	excinuclease ABC activity
BF89_5018	COG1396	sequence-specific DNA binding
BF89_5019	COG0252	asparaginase activity
BF89_5020	COG1027	Aspartate ammonia-lyase
BF89_5023	COG1063	alcohol dehydrogenase
BF89_5029	COG1113	amino acid transport
BF89_5030	COG1113	amino acid transport
BF89_5031	COG1280	lysine exporter protein (LysE YggA)
BF89_5032	COG3403	YqcI/YcgG family
BF89_5034	COG5577	PFAM Coat F domain
BF89_5037	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_5038	COG3848	Pyruvate phosphate dikinase
BF89_5038	COG0574	Belongs to the PEP-utilizing enzyme family
BF89_5041	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF89_5048	COG1960	acyl-CoA dehydrogenase activity
BF89_5050	COG0640	Transcriptional regulator
BF89_5051	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_5054	COG1414	Transcriptional regulator
BF89_5055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF89_5056	COG1984	allophanate hydrolase subunit 2
BF89_506	COG0456	acetyltransferase
BF89_5063	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF89_507	COG0523	cobalamin synthesis protein
BF89_5073	COG4335	DNA alkylation repair
BF89_5075	COG0833	amino acid
BF89_5077	COG0730	response to heat
BF89_508	COG4989	oxidoreductase activity
BF89_5083	COG0596	Alpha beta hydrolase
BF89_5084	COG0745	RESPONSE REGULATOR receiver
BF89_5085	COG0642	Histidine kinase
BF89_5089	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5093	COG0456	acetyltransferase
BF89_5094	COG2207	Transcriptional regulator
BF89_5099	COG1136	(ABC) transporter
BF89_5099	COG0577	efflux transmembrane transporter activity
BF89_510	COG1231	oxidoreductase activity
BF89_5101	COG1725	Transcriptional regulator
BF89_5108	COG1846	Transcriptional regulator
BF89_5109	COG0778	Nitroreductase
BF89_5111	COG0714	Associated with various cellular activities
BF89_5117	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF89_5119	COG0753	catalase activity
BF89_512	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_5120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF89_5122	COG0463	Glycosyl transferase, family 2
BF89_5127	COG0463	Glycosyl transferase, family 2
BF89_5133	COG0714	Associated with various cellular activities
BF89_5137	COG0346	lactoylglutathione lyase activity
BF89_5138	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_5140	COG3279	Response regulator of the LytR AlgR family
BF89_5142	COG4377	Putative membrane peptidase family (DUF2324)
BF89_5145	COG3655	Transcriptional regulator
BF89_5147	COG1785	Belongs to the alkaline phosphatase family
BF89_5148	COG3239	Fatty acid desaturase
BF89_5149	COG1690	Belongs to the RtcB family
BF89_515	COG0783	Belongs to the Dps family
BF89_5150	COG0833	amino acid
BF89_5151	COG1414	Transcriptional regulator
BF89_5152	COG4187	Peptidase family M20/M25/M40
BF89_5153	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_5154	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF89_5156	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_516	COG3949	Membrane
BF89_5160	COG2329	Antibiotic biosynthesis monooxygenase
BF89_5166	COG1070	Carbohydrate kinase
BF89_5167	COG2390	Transcriptional regulator
BF89_5169	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF89_5171	COG1879	ABC-type sugar transport system periplasmic component
BF89_5177	COG1595	DNA-templated transcription, initiation
BF89_5179	COG1388	LysM domain
BF89_5179	COG3584	3D domain protein
BF89_5187	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF89_5187	COG1605	Chorismate mutase
BF89_5188	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF89_5189	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF89_519	COG0840	transmembrane signaling receptor activity
BF89_5190	COG0287	Prephenate dehydrogenase
BF89_5193	COG1309	transcriptional regulator
BF89_5194	COG2409	Drug exporters of the RND superfamily
BF89_5194	COG1033	growth of symbiont in host cell
BF89_5195	COG1033	growth of symbiont in host cell
BF89_5195	COG2409	Drug exporters of the RND superfamily
BF89_5197	COG0488	(ABC) transporter
BF89_5198	COG1368	sulfuric ester hydrolase activity
BF89_5199	COG0861	Integral membrane protein TerC family
BF89_52	COG1595	DNA-templated transcription, initiation
BF89_5201	COG0726	polysaccharide deacetylase
BF89_5207	COG2318	DinB family
BF89_5208	COG0697	spore germination
BF89_5213	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF89_5222	COG1116	anion transmembrane transporter activity
BF89_5223	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_5224	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_5225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_5227	COG0628	permease
BF89_5236	COG1131	(ABC) transporter
BF89_524	COG2814	Major facilitator Superfamily
BF89_5240	COG5146	pantothenate kinase activity
BF89_5241	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF89_5242	COG0436	Aminotransferase
BF89_5249	COG2226	methyltransferase
BF89_525	COG0667	Aldo Keto reductase
BF89_5252	COG2261	transglycosylase associated protein
BF89_5256	COG0477	Major facilitator Superfamily
BF89_5256	COG2814	Major facilitator Superfamily
BF89_5257	COG4533	DNA binding
BF89_5258	COG0789	Transcriptional regulator
BF89_5259	COG1664	Polymer-forming cytoskeletal
BF89_526	COG0640	Transcriptional regulator
BF89_5261	COG2814	Major facilitator Superfamily
BF89_5265	COG1307	EDD domain protein, DegV family
BF89_5268	COG1164	Oligoendopeptidase f
BF89_527	COG1404	Belongs to the peptidase S8 family
BF89_5275	COG0745	RESPONSE REGULATOR receiver
BF89_5276	COG5002	protein histidine kinase activity
BF89_5277	COG2936	dipeptidyl-peptidase activity
BF89_528	COG2002	toxin-antitoxin pair type II binding
BF89_5285	COG4948	Mandelate Racemase Muconate Lactonizing
BF89_5287	COG4166	transmembrane transport
BF89_5288	COG0519	Catalyzes the synthesis of GMP from XMP
BF89_5289	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF89_529	COG0577	efflux transmembrane transporter activity
BF89_5292	COG0586	Pfam SNARE associated Golgi protein
BF89_5299	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_5300	COG3938	Belongs to the proline racemase family
BF89_5302	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF89_5303	COG1012	belongs to the aldehyde dehydrogenase family
BF89_5304	COG1115	amino acid carrier protein
BF89_5305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF89_5307	COG3397	chitin binding
BF89_5313	COG4637	Psort location Cytoplasmic, score
BF89_5316	COG0514	ATP-dependent DNA helicase (RecQ)
BF89_5317	COG2105	PFAM AIG2 family protein
BF89_5320	COG3973	AAA domain
BF89_5330	COG2333	competence protein COMEC
BF89_5330	COG0658	competence protein
BF89_5336	COG2205	protein histidine kinase activity
BF89_5340	COG3397	chitin binding
BF89_5341	COG2153	protein acetylation
BF89_5342	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF89_5345	COG0740	serine-type endopeptidase activity
BF89_5347	COG0517	IMP dehydrogenase activity
BF89_5347	COG4175	Glycine betaine
BF89_5348	COG4176	ABC-type proline glycine betaine transport system permease component
BF89_5354	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_5354	COG0456	acetyltransferase
BF89_5355	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_5357	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_5358	COG0022	dehydrogenase e1 component
BF89_5359	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_536	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF89_5360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF89_5364	COG1959	2 iron, 2 sulfur cluster binding
BF89_5368	COG1349	DNA-binding transcription factor activity
BF89_5372	COG3284	Transcriptional regulator
BF89_5378	COG1309	transcriptional regulator
BF89_5379	COG3844	kynureninase activity
BF89_538	COG1279	arginine transmembrane transporter activity
BF89_5380	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF89_5381	COG3483	tryptophan 2,3-dioxygenase activity
BF89_5384	COG3773	Cell wall hydrolase
BF89_5384	COG3409	Peptidoglycan-binding domain 1 protein
BF89_5385	COG2959	enzyme of heme biosynthesis
BF89_5388	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_5389	COG4129	membrane
BF89_539	COG2814	Major facilitator Superfamily
BF89_5395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5396	COG0697	spore germination
BF89_5398	COG0201	protein transport
BF89_5402	COG3227	Zinc metalloprotease (Elastase)
BF89_5403	COG1523	belongs to the glycosyl hydrolase 13 family
BF89_5407	COG0076	glutamate decarboxylase activity
BF89_541	COG1082	Xylose isomerase domain protein TIM barrel
BF89_5411	COG1011	Hydrolase
BF89_5416	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_5424	COG0322	excinuclease ABC activity
BF89_5427	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF89_5432	COG4667	esterase of the alpha-beta hydrolase superfamily
BF89_5438	COG3878	Protein conserved in bacteria
BF89_544	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_5445	COG1051	belongs to the nudix hydrolase family
BF89_5446	COG0592	DNA-directed DNA polymerase activity
BF89_5447	COG2816	NAD+ diphosphatase activity
BF89_5449	COG2223	nitrite transmembrane transporter activity
BF89_545	COG4264	IucA IucC family
BF89_5456	COG0697	spore germination
BF89_5457	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5458	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5461	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_5465	COG2814	Major facilitator Superfamily
BF89_547	COG1247	-acetyltransferase
BF89_5470	COG0693	protein deglycase activity
BF89_5478	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_548	COG1285	pathogenesis
BF89_5481	COG0604	alcohol dehydrogenase
BF89_5485	COG2205	protein histidine kinase activity
BF89_5488	COG1122	ATPase activity
BF89_5490	COG1794	racemase activity, acting on amino acids and derivatives
BF89_5491	COG1819	glycosyl
BF89_5493	COG5002	protein histidine kinase activity
BF89_5495	COG0561	phosphatase activity
BF89_5498	COG2124	cytochrome p450
BF89_550	COG0726	polysaccharide deacetylase
BF89_5503	COG2124	cytochrome p450
BF89_551	COG5002	protein histidine kinase activity
BF89_5518	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF89_552	COG0745	RESPONSE REGULATOR receiver
BF89_5520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5521	COG0460	homoserine dehydrogenase
BF89_5525	COG0577	efflux transmembrane transporter activity
BF89_5526	COG0577	efflux transmembrane transporter activity
BF89_5527	COG1136	(ABC) transporter
BF89_5532	COG2205	protein histidine kinase activity
BF89_5534	COG0745	RESPONSE REGULATOR receiver
BF89_5536	COG3773	Cell wall hydrolase
BF89_5539	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_554	COG1316	TRANSCRIPTIONal
BF89_5540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_5543	COG1063	alcohol dehydrogenase
BF89_5545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_5549	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_5552	COG2814	Major facilitator Superfamily
BF89_5554	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_5557	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_5557	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_5562	COG3227	Zinc metalloprotease (Elastase)
BF89_5567	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF89_5572	COG1686	Belongs to the peptidase S11 family
BF89_5573	COG2318	DinB family
BF89_5575	COG0572	uridine kinase
BF89_5576	COG1247	-acetyltransferase
BF89_559	COG0460	homoserine dehydrogenase
BF89_5590	COG3344	reverse transcriptase
BF89_56	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF89_5612	COG1923	regulation of RNA biosynthetic process
BF89_5614	COG0457	Tetratricopeptide repeat
BF89_5619	COG4974	Belongs to the 'phage' integrase family
BF89_5621	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF89_5623	COG2801	Transposase and inactivated derivatives
BF89_5625	COG2801	Transposase and inactivated derivatives
BF89_5628	COG2801	Transposase and inactivated derivatives
BF89_563	COG0726	polysaccharide deacetylase
BF89_5637	COG4974	Belongs to the 'phage' integrase family
BF89_5639	COG2002	toxin-antitoxin pair type II binding
BF89_565	COG0300	oxidoreductase activity
BF89_567	COG5002	protein histidine kinase activity
BF89_5677	COG2801	Transposase and inactivated derivatives
BF89_5681	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF89_5682	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF89_5685	COG0671	phosphoesterase, PA-phosphatase related
BF89_5686	COG4196	transglutaminase domain protein
BF89_569	COG0745	RESPONSE REGULATOR receiver
BF89_5692	COG2311	Membrane
BF89_570	COG1132	(ABC) transporter
BF89_571	COG1132	(ABC) transporter
BF89_5722	COG4962	Type ii secretion system protein e
BF89_573	COG0791	NLP P60 protein
BF89_573	COG1388	LysM domain
BF89_575	COG1686	Belongs to the peptidase S11 family
BF89_5767	COG3344	reverse transcriptase
BF89_5778	COG0791	NLP P60 protein
BF89_5778	COG0741	lytic transglycosylase activity
BF89_579	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF89_580	COG4988	ABC transporter
BF89_581	COG1294	oxidase, subunit
BF89_5813	COG1192	Involved in chromosome partitioning
BF89_5818	COG2801	Transposase and inactivated derivatives
BF89_582	COG1271	oxidase subunit
BF89_5824	COG1683	Conserved Protein
BF89_5825	COG1309	transcriptional regulator
BF89_584	COG1846	Transcriptional regulator
BF89_5842	COG0681	Belongs to the peptidase S26 family
BF89_5850	COG1280	lysine exporter protein (LysE YggA)
BF89_5855	COG4166	transmembrane transport
BF89_5859	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF89_5870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF89_5871	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF89_588	COG0583	DNA-binding transcription factor activity
BF89_592	COG0411	ABC transporter
BF89_594	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_595	COG2030	dehydratase
BF89_596	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_599	COG0523	cobalamin synthesis protein
BF89_6	COG1960	acyl-CoA dehydrogenase activity
BF89_600	COG1231	oxidoreductase activity
BF89_601	COG0039	L-malate dehydrogenase activity
BF89_602	COG0628	permease
BF89_605	COG0778	Nitroreductase
BF89_606	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF89_607	COG1959	2 iron, 2 sulfur cluster binding
BF89_608	COG0583	DNA-binding transcription factor activity
BF89_609	COG0697	spore germination
BF89_611	COG4549	nuclear export factor GLE1
BF89_612	COG1276	copper resistance
BF89_612	COG2372	response to copper ion
BF89_614	COG1114	Component of the transport system for branched-chain amino acids
BF89_615	COG1114	Component of the transport system for branched-chain amino acids
BF89_616	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_622	COG2132	Multicopper oxidase
BF89_623	COG0006	proline dipeptidase activity
BF89_627	COG4224	UPF0291 protein
BF89_629	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF89_63	COG1846	Transcriptional regulator
BF89_630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_632	COG2390	Transcriptional regulator
BF89_637	COG0531	amino acid
BF89_638	COG0531	amino acid
BF89_64	COG3961	Belongs to the TPP enzyme family
BF89_640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF89_643	COG1914	H( )-stimulated, divalent metal cation uptake system
BF89_648	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_65	COG2226	methyltransferase
BF89_653	COG4166	transmembrane transport
BF89_654	COG1073	alpha beta
BF89_658	COG0427	acetyl-CoA hydrolase
BF89_659	COG3279	Response regulator of the LytR AlgR family
BF89_661	COG3384	dioxygenase
BF89_667	COG2843	Capsule synthesis protein
BF89_669	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF89_67	COG3615	Tellurite resistance protein tehB
BF89_67	COG0500	methyltransferase
BF89_671	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF89_672	COG0440	acetolactate synthase activity
BF89_673	COG0028	Belongs to the TPP enzyme family
BF89_674	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_676	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_68	COG0577	efflux transmembrane transporter activity
BF89_68	COG1136	(ABC) transporter
BF89_680	COG2084	Dehydrogenase
BF89_683	COG2323	membrane
BF89_684	COG5566	PFAM Mor transcription activator
BF89_686	COG0733	neurotransmitter:sodium symporter activity
BF89_687	COG2244	polysaccharide biosynthetic process
BF89_690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_691	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_692	COG2223	nitrite transmembrane transporter activity
BF89_693	COG4166	transmembrane transport
BF89_694	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF89_696	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_697	COG0477	Major facilitator Superfamily
BF89_699	COG1966	Carbon starvation protein
BF89_704	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_705	COG1051	belongs to the nudix hydrolase family
BF89_717	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_718	COG0784	Response regulator, receiver
BF89_719	COG4191	Histidine kinase
BF89_720	COG0281	malic enzyme
BF89_721	COG1027	Aspartate ammonia-lyase
BF89_723	COG0528	UMP kinase activity
BF89_724	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_727	COG1131	(ABC) transporter
BF89_73	COG1309	transcriptional regulator
BF89_734	COG2733	membrane
BF89_741	COG0785	Cytochrome C biogenesis protein
BF89_745	COG3340	Belongs to the peptidase S51 family
BF89_746	COG0534	Mate efflux family protein
BF89_747	COG0534	Mate efflux family protein
BF89_751	COG0114	fumarate hydratase activity
BF89_752	COG1757	Na H antiporter
BF89_753	COG1216	Glycosyl transferase, family 2
BF89_753	COG0438	transferase activity, transferring glycosyl groups
BF89_755	COG0701	Predicted permease
BF89_756	COG0523	cobalamin synthesis protein
BF89_757	COG0697	spore germination
BF89_758	COG1802	Transcriptional regulator
BF89_764	COG0367	asparagine synthase
BF89_771	COG0406	alpha-ribazole phosphatase activity
BF89_773	COG1686	Belongs to the peptidase S11 family
BF89_778	COG1234	tRNA 3'-trailer cleavage
BF89_779	COG1177	transmembrane transport
BF89_78	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_780	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF89_781	COG3842	ATPase activity
BF89_782	COG0583	DNA-binding transcription factor activity
BF89_788	COG2329	Antibiotic biosynthesis monooxygenase
BF89_792	COG1309	transcriptional regulator
BF89_797	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_798	COG4786	Flagellar basal body rod
BF89_799	COG1419	protein localization to endoplasmic reticulum
BF89_800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF89_801	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF89_803	COG1987	bacterial-type flagellum assembly
BF89_804	COG1338	Plays a role in the flagellum-specific transport system
BF89_806	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_806	COG1776	CheC inhibitor of MCP methylation
BF89_808	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_809	COG0741	lytic transglycosylase activity
BF89_810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF89_815	COG0457	Tetratricopeptide repeat
BF89_815	COG0463	Glycosyl transferase, family 2
BF89_82	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF89_821	COG0463	Glycosyl transferase, family 2
BF89_823	COG0784	Response regulator, receiver
BF89_823	COG0835	chemotaxis
BF89_83	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_832	COG1157	protein secretion by the type III secretion system
BF89_834	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_836	COG1766	The M ring may be actively involved in energy transduction
BF89_837	COG1677	Flagellar hook-basal body complex protein FliE
BF89_838	COG1558	bacterial-type flagellum-dependent cell motility
BF89_839	COG1815	bacterial-type flagellum-dependent cell motility
BF89_84	COG2971	BadF BadG BcrA BcrD
BF89_844	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF89_845	COG1256	bacterial-type flagellum assembly
BF89_850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF89_853	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_853	COG1776	CheC inhibitor of MCP methylation
BF89_854	COG2198	Histidine kinase
BF89_854	COG0643	Histidine kinase
BF89_855	COG0643	Histidine kinase
BF89_855	COG2198	Histidine kinase
BF89_856	COG2201	protein-glutamate methylesterase activity
BF89_857	COG1360	Flagellar Motor Protein
BF89_858	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF89_860	COG1923	regulation of RNA biosynthetic process
BF89_871	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF89_872	COG2323	membrane
BF89_874	COG4978	Transcriptional regulator
BF89_874	COG0789	Transcriptional regulator
BF89_875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_876	COG0475	glutathione-regulated potassium exporter activity
BF89_878	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_879	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_880	COG3162	membrane
BF89_883	COG1280	lysine exporter protein (LysE YggA)
BF89_89	COG1649	PFAM Uncharacterised BCR, COG1649
BF89_891	COG0328	RNA-DNA hybrid ribonuclease activity
BF89_895	COG0454	-acetyltransferase
BF89_898	COG0438	transferase activity, transferring glycosyl groups
BF89_9	COG1309	transcriptional regulator
BF89_901	COG1215	transferase activity, transferring glycosyl groups
BF89_904	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF89_909	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_912	COG0754	glutathionylspermidine amidase activity
BF89_917	COG0456	acetyltransferase
BF89_919	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_921	COG2311	Membrane
BF89_922	COG2233	PERMEase
BF89_924	COG0024	Methionine aminopeptidase
BF89_925	COG3173	Aminoglycoside phosphotransferase
BF89_927	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF89_928	COG1199	ATP-dependent helicase activity
BF89_930	COG0116	Belongs to the methyltransferase superfamily
BF89_932	COG4474	Belongs to the UPF0398 family
BF89_94	COG1595	DNA-templated transcription, initiation
BF89_941	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF89_941	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_943	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF89_944	COG3935	DnaD domain protein
BF89_948	COG1199	ATP-dependent helicase activity
BF89_948	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF89_949	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF89_949	COG1199	ATP-dependent helicase activity
BF89_956	COG0438	transferase activity, transferring glycosyl groups
BF89_957	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_960	COG1694	Mazg nucleotide pyrophosphohydrolase
BF89_961	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_963	COG2738	Putative neutral zinc metallopeptidase
BF89_966	COG4347	Protein of unknown function (DUF1405)
BF89_968	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF89_972	COG0457	Tetratricopeptide repeat
BF89_973	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF89_976	COG0105	UTP biosynthetic process
BF89_977	COG0142	geranyltranstransferase activity
BF89_979	COG0142	geranyltranstransferase activity
BF89_982	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_996	COG0252	asparaginase activity
BF89_997	COG0492	ferredoxin-NADP+ reductase activity