locus-tag	class	description
OM985_00010	COG0592	DNA-directed DNA polymerase activity
OM985_00015	COG2501	S4 domain
OM985_00025	COG0187	DNA topoisomerase II activity
OM985_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OM985_00055	COG0516	GMP reductase activity
OM985_00055	COG0517	IMP dehydrogenase activity
OM985_00060	COG1686	Belongs to the peptidase S11 family
OM985_00090	COG1428	Deoxynucleoside kinase
OM985_00095	COG1428	Deoxynucleoside kinase
OM985_00100	COG1335	isochorismatase
OM985_00105	COG0590	tRNA wobble adenosine to inosine editing
OM985_00115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OM985_00160	COG1982	Orn Lys Arg decarboxylase major
OM985_00170	COG0470	DNA polymerase III
OM985_00175	COG1774	PSP1 C-terminal conserved region
OM985_00185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OM985_00195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OM985_00200	COG2002	toxin-antitoxin pair type II binding
OM985_00205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM985_00205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM985_00210	COG0084	hydrolase, TatD family'
OM985_00215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OM985_00230	COG4466	Protein conserved in bacteria
OM985_00245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM985_00250	COG0251	oxidation-reduction process
OM985_00280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM985_00285	COG2002	toxin-antitoxin pair type II binding
OM985_00290	COG2244	polysaccharide biosynthetic process
OM985_00295	COG3956	TIGRFAM MazG family protein
OM985_00300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OM985_00320	COG1098	S1 RNA binding domain
OM985_00335	COG2208	phosphoserine phosphatase activity
OM985_00340	COG0037	tRNA processing
OM985_00345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM985_00350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OM985_00365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM985_00370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM985_00375	COG0512	Glutamine amidotransferase of anthranilate synthase
OM985_00380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM985_00385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM985_00390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM985_00395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM985_00400	COG1396	sequence-specific DNA binding
OM985_00405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM985_00435	COG3880	PFAM UvrB UvrC protein
OM985_00445	COG0542	response to heat
OM985_00450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OM985_00460	COG4956	integral membrane protein (PIN domain superfamily)
OM985_00480	COG1045	serine acetyltransferase
OM985_00495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM985_00500	COG3688	RNA-binding protein containing a PIN domain
OM985_00515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OM985_00520	COG0250	Participates in transcription elongation, termination and antitermination
OM985_00525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OM985_00545	COG2813	Specifically methylates the guanine in position
OM985_00555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OM985_00560	COG1358	cellular component organization or biogenesis
OM985_00630	COG0255	Belongs to the universal ribosomal protein uL29 family
OM985_00690	COG0201	protein transport
OM985_00700	COG0024	Methionine aminopeptidase
OM985_00710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OM985_00745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OM985_00770	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM985_00775	COG0489	protein tyrosine kinase activity
OM985_00785	COG2194	sulfuric ester hydrolase activity
OM985_00790	COG0726	polysaccharide deacetylase
OM985_00870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OM985_00875	COG4856	YbbR-like protein
OM985_00890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OM985_00895	COG0596	Alpha beta hydrolase
OM985_00915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OM985_00920	COG1506	peptidase
OM985_00920	COG0823	Involved in the tonB-independent uptake of proteins
OM985_00920	COG4946	Tricorn protease homolog
OM985_00955	COG2011	ABC-type metal ion transport system permease component
OM985_00960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM985_00965	COG1464	Belongs to the NlpA lipoprotein family
OM985_00970	COG0604	alcohol dehydrogenase
OM985_00980	COG0277	FAD linked oxidase domain protein
OM985_00985	COG2271	Major facilitator Superfamily
OM985_00995	COG2814	Major facilitator Superfamily
OM985_01010	COG0601	transmembrane transport
OM985_01015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM985_01020	COG0444	Belongs to the ABC transporter superfamily
OM985_01025	COG4608	Belongs to the ABC transporter superfamily
OM985_01030	COG4166	transmembrane transport
OM985_01040	COG2207	Transcriptional regulator
OM985_01055	COG4166	transmembrane transport
OM985_01060	COG4166	transmembrane transport
OM985_01065	COG0656	L-ascorbic acid biosynthetic process
OM985_01085	COG4149	molybdate abc transporter
OM985_01095	COG1910	domain protein
OM985_01105	COG0583	DNA-binding transcription factor activity
OM985_01110	COG0697	spore germination
OM985_01125	COG0204	Acyl-transferase
OM985_01135	COG1609	Transcriptional regulator
OM985_01145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_01155	COG0084	hydrolase, TatD family'
OM985_01160	COG5298	Protein conserved in bacteria
OM985_01185	COG0488	(ABC) transporter
OM985_01200	COG0747	negative chemotaxis
OM985_01205	COG0601	transmembrane transport
OM985_01210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM985_01215	COG0444	Belongs to the ABC transporter superfamily
OM985_01240	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OM985_01245	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM985_01255	COG2814	Major facilitator Superfamily
OM985_01265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM985_01275	COG4294	response to UV
OM985_01280	COG0457	Tetratricopeptide repeat
OM985_01280	COG0705	Rhomboid family
OM985_01290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM985_01295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM985_01300	COG0864	Transcriptional regulator
OM985_01305	COG2337	Toxic component of a toxin-antitoxin (TA) module
OM985_01310	COG2183	response to ionizing radiation
OM985_01405	COG0802	atpase or kinase
OM985_01410	COG1214	PFAM Peptidase M22, glycoprotease
OM985_01415	COG0456	acetyltransferase
OM985_01425	COG0488	(ABC) transporter
OM985_01440	COG1266	CAAX protease self-immunity
OM985_01460	COG2252	PERMEase
OM985_01470	COG5002	protein histidine kinase activity
OM985_01500	COG2226	methyltransferase
OM985_01545	COG1968	undecaprenyl-diphosphatase activity
OM985_01560	COG2205	protein histidine kinase activity
OM985_01565	COG0745	RESPONSE REGULATOR receiver
OM985_01590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OM985_01595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OM985_01600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OM985_01610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM985_01625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OM985_01635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM985_01645	COG0151	Belongs to the GarS family
OM985_01670	COG0210	DNA helicase
OM985_01680	COG4851	CamS sex pheromone cAM373 precursor
OM985_01700	COG1335	isochorismatase
OM985_01705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM985_01710	COG2011	ABC-type metal ion transport system permease component
OM985_01715	COG1464	Belongs to the NlpA lipoprotein family
OM985_01735	COG1846	Transcriptional regulator
OM985_01760	COG1597	lipid kinase activity
OM985_01765	COG0546	phosphoglycolate phosphatase activity
OM985_01770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OM985_01780	COG1012	belongs to the aldehyde dehydrogenase family
OM985_01785	COG2076	Multidrug Resistance protein
OM985_01790	COG2309	aminopeptidase activity
OM985_01805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_01810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM985_01815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM985_01825	COG4807	Protein conserved in bacteria
OM985_01850	COG1757	Na H antiporter
OM985_01855	COG1473	amidohydrolase
OM985_01870	COG0450	alkyl hydroperoxide reductase
OM985_01890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_01900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_01915	COG0166	Belongs to the GPI family
OM985_01950	COG5002	protein histidine kinase activity
OM985_01970	COG3541	Predicted nucleotidyltransferase
OM985_01975	COG2814	Major facilitator Superfamily
OM985_01980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM985_01980	COG0723	plastoquinol--plastocyanin reductase activity
OM985_01990	COG0765	amino acid transport
OM985_01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM985_02005	COG0840	transmembrane signaling receptor activity
OM985_02010	COG0840	transmembrane signaling receptor activity
OM985_02015	COG0366	Alpha amylase catalytic
OM985_02020	COG1263	PTS System
OM985_02020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_02020	COG2190	(PTS) system
OM985_02050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OM985_02065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM985_02075	COG1116	anion transmembrane transporter activity
OM985_02080	COG0488	(ABC) transporter
OM985_02125	COG2270	Major facilitator Superfamily
OM985_02140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM985_02155	COG2310	stress, protein
OM985_02160	COG2310	stress, protein
OM985_02165	COG2310	stress, protein
OM985_02170	COG0861	Integral membrane protein TerC family
OM985_02180	COG3853	Toxic anion resistance protein (TelA)
OM985_02195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM985_02205	COG1295	ribonuclease BN
OM985_02210	COG2217	Heavy metal translocating P-type atpase
OM985_02215	COG0697	spore germination
OM985_02235	COG0586	Pfam SNARE associated Golgi protein
OM985_02250	COG3871	stress protein (general stress protein 26)
OM985_02255	COG0387	Pfam Sodium calcium exchanger
OM985_02265	COG0535	radical SAM domain protein
OM985_02290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM985_02295	COG0582	viral genome integration into host DNA
OM985_02305	COG1396	sequence-specific DNA binding
OM985_02325	COG1396	sequence-specific DNA binding
OM985_02360	COG1484	DNA-dependent DNA replication
OM985_02590	COG0101	tRNA pseudouridine synthase activity
OM985_02600	COG3829	transcription factor binding
OM985_02610	COG0833	amino acid
OM985_02615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM985_02645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_02645	COG1263	PTS System
OM985_02650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM985_02665	COG0463	Glycosyl transferase, family 2
OM985_02680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OM985_02680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM985_02695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OM985_02715	COG1228	amidohydrolase
OM985_02720	COG1090	epimerase
OM985_02750	COG1988	membrane-bound metal-dependent
OM985_02755	COG1194	a g-specific adenine glycosylase
OM985_02780	COG1132	(ABC) transporter
OM985_02785	COG4129	membrane
OM985_02790	COG0070	glutamate synthase
OM985_02790	COG0067	glutamate synthase
OM985_02790	COG0069	glutamate synthase activity
OM985_02800	COG4555	ABC transporter
OM985_02820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM985_02825	COG0735	belongs to the Fur family
OM985_02920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OM985_02925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM985_02935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM985_02945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM985_02955	COG2766	serine protein kinase
OM985_02975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM985_02985	COG1585	Membrane protein implicated in regulation of membrane protease activity
OM985_02990	COG2268	Band 7 protein
OM985_03000	COG3290	protein histidine kinase activity
OM985_03010	COG2851	Citrate transporter
OM985_03030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OM985_03035	COG3842	ATPase activity
OM985_03040	COG1175	transmembrane transport
OM985_03045	COG0395	ABC-type sugar transport system, permease component
OM985_03055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OM985_03060	COG0745	RESPONSE REGULATOR receiver
OM985_03065	COG5002	protein histidine kinase activity
OM985_03075	COG4990	cell redox homeostasis
OM985_03085	COG3290	protein histidine kinase activity
OM985_03090	COG4565	transcriptional regulatory protein
OM985_03095	COG3493	citrate carrier protein
OM985_03100	COG0281	malic enzyme
OM985_03115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_03125	COG5002	protein histidine kinase activity
OM985_03130	COG0745	RESPONSE REGULATOR receiver
OM985_03140	COG0456	acetyltransferase
OM985_03140	COG0454	-acetyltransferase
OM985_03145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM985_03150	COG3383	formate dehydrogenase (NAD+) activity
OM985_03170	COG0531	amino acid
OM985_03175	COG0640	Transcriptional regulator
OM985_03180	COG2217	Heavy metal translocating P-type atpase
OM985_03185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OM985_03200	COG3227	Zinc metalloprotease (Elastase)
OM985_03220	COG2720	vancomycin resistance protein
OM985_03225	COG1316	TRANSCRIPTIONal
OM985_03230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_03235	COG0346	lactoylglutathione lyase activity
OM985_03245	COG1027	Aspartate ammonia-lyase
OM985_03250	COG1620	l-lactate permease
OM985_03265	COG3104	oligopeptide transport
OM985_03270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_03275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_03280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_03290	COG2226	methyltransferase
OM985_03295	COG0156	8-amino-7-oxononanoate synthase activity
OM985_03310	COG4548	von Willebrand factor, type A
OM985_03315	COG0714	Associated with various cellular activities
OM985_03320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM985_03340	COG0531	amino acid
OM985_03345	COG2188	Transcriptional regulator
OM985_03350	COG1263	PTS System
OM985_03350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_03355	COG0366	Alpha amylase catalytic
OM985_03370	COG0697	spore germination
OM985_03380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM985_03385	COG1115	amino acid carrier protein
OM985_03390	COG1126	abc transporter atp-binding protein
OM985_03395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM985_03400	COG0765	amino acid transport
OM985_03405	COG0765	amino acid transport
OM985_03410	COG0833	amino acid
OM985_03435	COG2378	regulation of single-species biofilm formation
OM985_03440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM985_03445	COG5002	protein histidine kinase activity
OM985_03460	COG0659	secondary active sulfate transmembrane transporter activity
OM985_03475	COG0747	negative chemotaxis
OM985_03485	COG0601	transmembrane transport
OM985_03490	COG4608	Belongs to the ABC transporter superfamily
OM985_03500	COG2271	Major facilitator Superfamily
OM985_03505	COG1846	Transcriptional regulator
OM985_03515	COG1609	Transcriptional regulator
OM985_03520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM985_03535	COG1172	Belongs to the binding-protein-dependent transport system permease family
OM985_03540	COG1879	ABC-type sugar transport system periplasmic component
OM985_03565	COG1063	alcohol dehydrogenase
OM985_03580	COG3568	Endonuclease Exonuclease Phosphatase
OM985_03605	COG1968	undecaprenyl-diphosphatase activity
OM985_03610	COG0840	transmembrane signaling receptor activity
OM985_03615	COG3584	3D domain protein
OM985_03615	COG1388	LysM domain
OM985_03620	COG1476	TRANSCRIPTIONal
OM985_03635	COG3104	oligopeptide transport
OM985_03640	COG1114	Component of the transport system for branched-chain amino acids
OM985_03655	COG1113	amino acid transport
OM985_03660	COG2252	PERMEase
OM985_03685	COG0569	domain protein
OM985_03685	COG0475	glutathione-regulated potassium exporter activity
OM985_03700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM985_03705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM985_03710	COG4990	cell redox homeostasis
OM985_03725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM985_03730	COG0697	spore germination
OM985_03735	COG0531	amino acid
OM985_03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OM985_03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OM985_03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OM985_03755	COG1918	ferrous iron import across plasma membrane
OM985_03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM985_03765	COG0573	inorganic phosphate transmembrane transporter activity
OM985_03770	COG0581	inorganic phosphate transmembrane transporter activity
OM985_03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM985_03895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OM985_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OM985_03920	COG1116	anion transmembrane transporter activity
OM985_03925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM985_03930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM985_03935	COG0352	thiamine-phosphate diphosphorylase activity
OM985_03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM985_03945	COG2104	thiamine diphosphate biosynthetic process
OM985_03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM985_03960	COG0351	phosphomethylpyrimidine kinase
OM985_04000	COG2205	protein histidine kinase activity
OM985_04005	COG2814	Major facilitator Superfamily
OM985_04010	COG1846	Transcriptional regulator
OM985_04025	COG2252	PERMEase
OM985_04030	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_04045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM985_04050	COG1621	beta-fructofuranosidase activity
OM985_04055	COG1263	PTS System
OM985_04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_04060	COG1609	Transcriptional regulator
OM985_04070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM985_04075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM985_04110	COG0778	Nitroreductase
OM985_04115	COG2719	SpoVR family
OM985_04140	COG0446	pyridine nucleotide-disulphide oxidoreductase
OM985_04145	COG1937	Protein conserved in bacteria
OM985_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM985_04150	COG0425	Belongs to the sulfur carrier protein TusA family
OM985_04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM985_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_04160	COG0425	Belongs to the sulfur carrier protein TusA family
OM985_04175	COG2210	Belongs to the sulfur carrier protein TusA family
OM985_04180	COG0730	response to heat
OM985_04190	COG1316	TRANSCRIPTIONal
OM985_04195	COG0604	alcohol dehydrogenase
OM985_04200	COG1283	sodium-dependent phosphate transmembrane transporter activity
OM985_04215	COG3711	transcriptional antiterminator
OM985_04215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM985_04220	COG1447	Phosphotransferase system cellobiose-specific component IIA
OM985_04225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM985_04245	COG1388	LysM domain
OM985_04245	COG3584	3D domain protein
OM985_04250	COG0577	efflux transmembrane transporter activity
OM985_04255	COG1136	(ABC) transporter
OM985_04265	COG5522	Integral membrane protein (intg_mem_TP0381)
OM985_04280	COG1114	Component of the transport system for branched-chain amino acids
OM985_04285	COG3546	catalase activity
OM985_04320	COG0586	Pfam SNARE associated Golgi protein
OM985_04355	COG0531	amino acid
OM985_04360	COG0475	glutathione-regulated potassium exporter activity
OM985_04370	COG1737	Transcriptional regulator
OM985_04380	COG1263	PTS System
OM985_04380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_04390	COG2259	Doxx family
OM985_04405	COG0697	spore germination
OM985_04410	COG1522	sequence-specific DNA binding
OM985_04425	COG2076	Multidrug Resistance protein
OM985_04430	COG1309	transcriptional regulator
OM985_04435	COG2814	Major facilitator Superfamily
OM985_04440	COG1733	regulation of RNA biosynthetic process
OM985_04450	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM985_04455	COG4533	DNA binding
OM985_04460	COG2211	Major facilitator Superfamily
OM985_04470	COG0693	protein deglycase activity
OM985_04475	COG0753	catalase activity
OM985_04485	COG0531	amino acid
OM985_04490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OM985_04500	COG1012	belongs to the aldehyde dehydrogenase family
OM985_04505	COG1132	(ABC) transporter
OM985_04515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM985_04520	COG0765	amino acid transport
OM985_04525	COG1126	abc transporter atp-binding protein
OM985_04540	COG0189	ligase activity
OM985_04570	COG0028	Belongs to the TPP enzyme family
OM985_04575	COG3527	Alpha-acetolactate decarboxylase
OM985_04590	COG0561	phosphatase activity
OM985_04605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM985_04620	COG0659	secondary active sulfate transmembrane transporter activity
OM985_04640	COG0653	protein targeting
OM985_04645	COG2244	polysaccharide biosynthetic process
OM985_04655	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM985_04660	COG4196	transglutaminase domain protein
OM985_04675	COG1696	Membrane protein involved in D-alanine export
OM985_04690	COG1024	Enoyl-CoA hydratase
OM985_04710	COG1363	Peptidase, m42
OM985_04730	COG3938	Belongs to the proline racemase family
OM985_04770	COG0601	transmembrane transport
OM985_04775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM985_04785	COG4608	Belongs to the ABC transporter superfamily
OM985_04820	COG0477	Major facilitator Superfamily
OM985_04825	COG3290	protein histidine kinase activity
OM985_04830	COG4565	transcriptional regulatory protein
OM985_04835	COG3181	Tripartite tricarboxylate transporter family receptor
OM985_04865	COG0789	Transcriptional regulator
OM985_04865	COG4978	Transcriptional regulator
OM985_04880	COG0305	Participates in initiation and elongation during chromosome replication
OM985_04920	COG0477	Major facilitator Superfamily
OM985_04965	COG3320	Male sterility
OM985_04965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM985_04970	COG1309	transcriptional regulator
OM985_04990	COG1183	phosphatidylcholine synthase activity
OM985_05010	COG2376	Dihydroxyacetone kinase
OM985_05020	COG2376	Dihydroxyacetone kinase
OM985_05025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM985_05030	COG1959	2 iron, 2 sulfur cluster binding
OM985_05060	COG2770	Histidine kinase
OM985_05060	COG3437	response regulator, receiver
OM985_05115	COG3237	CsbD-like
OM985_05140	COG1191	sigma factor activity
OM985_05150	COG2208	phosphoserine phosphatase activity
OM985_05155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM985_05160	COG0784	Response regulator, receiver
OM985_05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM985_05160	COG2198	Histidine kinase
OM985_05160	COG2205	protein histidine kinase activity
OM985_05215	COG0420	3'-5' exonuclease activity
OM985_05240	COG1309	transcriptional regulator
OM985_05245	COG2814	Major facilitator Superfamily
OM985_05250	COG0346	lactoylglutathione lyase activity
OM985_05255	COG0346	lactoylglutathione lyase activity
OM985_05260	COG0457	Tetratricopeptide repeat
OM985_05270	COG2267	carboxylic ester hydrolase activity
OM985_05290	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OM985_05295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM985_05305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OM985_05345	COG0477	Major facilitator Superfamily
OM985_05350	COG0477	Major facilitator Superfamily
OM985_05360	COG3973	AAA domain
OM985_05365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM985_05385	COG4980	gas vesicle protein
OM985_05390	COG0537	adenosine 5'-monophosphoramidase activity
OM985_05395	COG1131	(ABC) transporter
OM985_05400	COG4473	ABC transporter
OM985_05415	COG1309	transcriptional regulator
OM985_05425	COG3402	PFAM membrane-flanked domain
OM985_05470	COG3402	PFAM membrane-flanked domain
OM985_05475	COG3428	Bacterial PH domain
OM985_05480	COG2329	Antibiotic biosynthesis monooxygenase
OM985_05485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM985_05490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OM985_05495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM985_05500	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OM985_05535	COG1309	transcriptional regulator
OM985_05540	COG1511	domain protein
OM985_05575	COG1234	tRNA 3'-trailer cleavage
OM985_05580	COG0095	Lipoate-protein ligase
OM985_05590	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_05620	COG3209	COG3209 Rhs family protein
OM985_05665	COG1078	dGTPase activity
OM985_05675	COG1595	DNA-templated transcription, initiation
OM985_05680	COG3708	Transcriptional regulator
OM985_05680	COG2207	Transcriptional regulator
OM985_05695	COG2205	protein histidine kinase activity
OM985_05700	COG0745	RESPONSE REGULATOR receiver
OM985_05725	COG0501	Belongs to the peptidase M48B family
OM985_05730	COG0840	transmembrane signaling receptor activity
OM985_05735	COG0697	spore germination
OM985_05755	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OM985_05760	COG2224	Isocitrate lyase
OM985_05785	COG4903	ComK protein
OM985_05790	COG0398	Pfam SNARE associated Golgi protein
OM985_05800	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OM985_05805	COG1074	ATP-dependent DNA helicase activity
OM985_05850	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM985_05875	COG0367	asparagine synthase
OM985_05880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM985_05885	COG0753	catalase activity
OM985_05890	COG0004	ammonium transporteR
OM985_05910	COG2996	Protein conserved in bacteria
OM985_05920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM985_05930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_05945	COG0561	phosphatase activity
OM985_05955	COG0542	response to heat
OM985_05965	COG2267	carboxylic ester hydrolase activity
OM985_05980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_05985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM985_05990	COG5504	Zn-dependent protease
OM985_06000	COG0180	Tryptophanyl-tRNA synthetase
OM985_06010	COG4166	transmembrane transport
OM985_06015	COG0601	transmembrane transport
OM985_06020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM985_06025	COG0444	Belongs to the ABC transporter superfamily
OM985_06030	COG4608	Belongs to the ABC transporter superfamily
OM985_06035	COG0534	Mate efflux family protein
OM985_06040	COG4166	transmembrane transport
OM985_06055	COG0861	Integral membrane protein TerC family
OM985_06060	COG4862	establishment of competence for transformation
OM985_06065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM985_06075	COG1164	Oligoendopeptidase f
OM985_06085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM985_06090	COG2346	COG2346, Truncated hemoglobins
OM985_06095	COG4116	CYTH
OM985_06105	COG2357	RelA SpoT domain protein
OM985_06115	COG0564	pseudouridine synthase activity
OM985_06135	COG0463	Glycosyl transferase, family 2
OM985_06135	COG1216	Glycosyl transferase, family 2
OM985_06155	COG0457	Tetratricopeptide repeat
OM985_06155	COG0463	Glycosyl transferase, family 2
OM985_06175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OM985_06190	COG1091	dTDP-4-dehydrorhamnose reductase activity
OM985_06235	COG2153	protein acetylation
OM985_06245	COG2382	esterase
OM985_06260	COG5492	domain, Protein
OM985_06265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM985_06275	COG0512	Glutamine amidotransferase of anthranilate synthase
OM985_06275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OM985_06310	COG1620	l-lactate permease
OM985_06315	COG5634	Uncharacterized conserved protein (DUF2278)
OM985_06370	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM985_06380	COG1476	TRANSCRIPTIONal
OM985_06440	COG2226	methyltransferase
OM985_06450	COG1686	Belongs to the peptidase S11 family
OM985_06455	COG0681	Belongs to the peptidase S26 family
OM985_06490	COG1012	belongs to the aldehyde dehydrogenase family
OM985_06495	COG3842	ATPase activity
OM985_06500	COG1176	ABC-type spermidine putrescine transport system, permease component I
OM985_06505	COG1177	transmembrane transport
OM985_06510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OM985_06520	COG2409	Drug exporters of the RND superfamily
OM985_06530	COG0564	pseudouridine synthase activity
OM985_06540	COG2340	Cysteine-rich secretory protein family
OM985_06545	COG0247	lactate metabolic process
OM985_06550	COG0277	FAD linked oxidase domain protein
OM985_06555	COG3835	regulator
OM985_06565	COG0745	RESPONSE REGULATOR receiver
OM985_06570	COG5002	protein histidine kinase activity
OM985_06575	COG2186	Transcriptional regulator
OM985_06595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM985_06605	COG2116	formate transmembrane transporter activity
OM985_06610	COG0861	Integral membrane protein TerC family
OM985_06615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OM985_06625	COG2030	dehydratase
OM985_06645	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_06650	COG3243	poly(R)-hydroxyalkanoic acid synthase
OM985_06655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM985_06660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OM985_06675	COG1840	ABC-type Fe3 transport system, periplasmic component
OM985_06705	COG1349	DNA-binding transcription factor activity
OM985_06725	COG2861	carbohydrate metabolic process
OM985_06735	COG3852	Histidine kinase
OM985_06740	COG1846	Transcriptional regulator
OM985_06750	COG2318	DinB family
OM985_06760	COG5002	protein histidine kinase activity
OM985_06770	COG0720	synthase
OM985_06785	COG4873	Protein conserved in bacteria
OM985_06815	COG1780	Probably involved in ribonucleotide reductase function
OM985_06835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM985_06840	COG1725	Transcriptional regulator
OM985_06845	COG1131	(ABC) transporter
OM985_06855	COG1131	(ABC) transporter
OM985_06860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM985_06875	COG1522	sequence-specific DNA binding
OM985_06885	COG1335	isochorismatase
OM985_06895	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM985_06900	COG2070	2-Nitropropane dioxygenase
OM985_06905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OM985_06915	COG1696	Membrane protein involved in D-alanine export
OM985_06940	COG0716	FMN binding
OM985_06955	COG3173	Aminoglycoside phosphotransferase
OM985_06975	COG0534	Mate efflux family protein
OM985_06980	COG1968	undecaprenyl-diphosphatase activity
OM985_06995	COG1846	Transcriptional regulator
OM985_07005	COG1301	dicarboxylic acid transport
OM985_07010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OM985_07015	COG4709	membrane
OM985_07020	COG3874	Sporulation protein YtfJ
OM985_07045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM985_07050	COG0028	Belongs to the TPP enzyme family
OM985_07055	COG0440	acetolactate synthase activity
OM985_07060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM985_07070	COG0473	3-isopropylmalate dehydrogenase activity
OM985_07095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM985_07130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OM985_07145	COG1183	phosphatidylcholine synthase activity
OM985_07150	COG1368	sulfuric ester hydrolase activity
OM985_07160	COG0019	diaminopimelate decarboxylase activity
OM985_07180	COG0529	Catalyzes the synthesis of activated sulfate
OM985_07185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM985_07205	COG1648	precorrin-2 dehydrogenase activity
OM985_07210	COG0733	neurotransmitter:sodium symporter activity
OM985_07230	COG1757	Na H antiporter
OM985_07245	COG4758	membrane
OM985_07250	COG4585	Histidine kinase
OM985_07255	COG2197	response regulator
OM985_07265	COG1114	Component of the transport system for branched-chain amino acids
OM985_07275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM985_07300	COG1017	nitric oxide dioxygenase activity
OM985_07300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OM985_07315	COG0730	response to heat
OM985_07320	COG0306	phosphate transporter
OM985_07325	COG1392	Phosphate transport regulator
OM985_07330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM985_07350	COG1801	Protein of unknown function DUF72
OM985_07360	COG0582	viral genome integration into host DNA
OM985_07365	COG5002	protein histidine kinase activity
OM985_07385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM985_07385	COG0392	lysyltransferase activity
OM985_07400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM985_07405	COG1686	Belongs to the peptidase S11 family
OM985_07410	COG2715	membrane protein required for spore maturation
OM985_07415	COG0700	Nucleoside recognition
OM985_07420	COG1187	pseudouridine synthase activity
OM985_07430	COG1333	cytochrome c biogenesis protein
OM985_07435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM985_07440	COG0745	RESPONSE REGULATOR receiver
OM985_07445	COG5002	protein histidine kinase activity
OM985_07450	COG2096	Adenosyltransferase
OM985_07465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OM985_07470	COG1141	Ferredoxin
OM985_07475	COG4955	Helix-turn-helix domain
OM985_07480	COG0514	ATP-dependent DNA helicase (RecQ)
OM985_07485	COG1266	CAAX protease self-immunity
OM985_07505	COG4862	establishment of competence for transformation
OM985_07510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OM985_07530	COG0492	ferredoxin-NADP+ reductase activity
OM985_07605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OM985_07620	COG0142	geranyltranstransferase activity
OM985_07630	COG0142	geranyltranstransferase activity
OM985_07650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM985_07655	COG0457	Tetratricopeptide repeat
OM985_07675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM985_07685	COG4347	Protein of unknown function (DUF1405)
OM985_07700	COG2738	Putative neutral zinc metallopeptidase
OM985_07710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_07715	COG1694	Mazg nucleotide pyrophosphohydrolase
OM985_07730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM985_07735	COG0438	transferase activity, transferring glycosyl groups
OM985_07770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM985_07770	COG1199	ATP-dependent helicase activity
OM985_07790	COG3935	DnaD domain protein
OM985_07795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM985_07805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM985_07805	COG4499	WXG100 protein secretion system (Wss), protein YukC
OM985_07865	COG0116	Belongs to the methyltransferase superfamily
OM985_07875	COG1199	ATP-dependent helicase activity
OM985_07880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OM985_07890	COG3173	Aminoglycoside phosphotransferase
OM985_07895	COG0024	Methionine aminopeptidase
OM985_07905	COG2233	PERMEase
OM985_07910	COG2311	Membrane
OM985_07915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OM985_07925	COG0456	acetyltransferase
OM985_07975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM985_08000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OM985_08015	COG1215	transferase activity, transferring glycosyl groups
OM985_08020	COG0438	transferase activity, transferring glycosyl groups
OM985_08035	COG0454	-acetyltransferase
OM985_08055	COG0328	RNA-DNA hybrid ribonuclease activity
OM985_08095	COG1280	lysine exporter protein (LysE YggA)
OM985_08110	COG3162	membrane
OM985_08115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM985_08120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM985_08130	COG0475	glutathione-regulated potassium exporter activity
OM985_08135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OM985_08140	COG0789	Transcriptional regulator
OM985_08140	COG4978	Transcriptional regulator
OM985_08150	COG2323	membrane
OM985_08155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OM985_08210	COG1923	regulation of RNA biosynthetic process
OM985_08220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM985_08225	COG1360	Flagellar Motor Protein
OM985_08230	COG2201	protein-glutamate methylesterase activity
OM985_08240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM985_08240	COG1776	CheC inhibitor of MCP methylation
OM985_08255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM985_08275	COG1256	bacterial-type flagellum assembly
OM985_08300	COG1815	bacterial-type flagellum-dependent cell motility
OM985_08305	COG1558	bacterial-type flagellum-dependent cell motility
OM985_08320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM985_08330	COG1157	protein secretion by the type III secretion system
OM985_08375	COG0463	Glycosyl transferase, family 2
OM985_08405	COG0463	Glycosyl transferase, family 2
OM985_08405	COG0457	Tetratricopeptide repeat
OM985_08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM985_08425	COG0741	lytic transglycosylase activity
OM985_08440	COG1776	CheC inhibitor of MCP methylation
OM985_08440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM985_08450	COG1338	Plays a role in the flagellum-specific transport system
OM985_08455	COG1987	bacterial-type flagellum assembly
OM985_08465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM985_08470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM985_08480	COG4786	Flagellar basal body rod
OM985_08485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM985_08510	COG1309	transcriptional regulator
OM985_08530	COG2329	Antibiotic biosynthesis monooxygenase
OM985_08555	COG0583	DNA-binding transcription factor activity
OM985_08565	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM985_08575	COG1234	tRNA 3'-trailer cleavage
OM985_08600	COG1686	Belongs to the peptidase S11 family
OM985_08610	COG0406	alpha-ribazole phosphatase activity
OM985_08640	COG0367	asparagine synthase
OM985_08670	COG1802	Transcriptional regulator
OM985_08675	COG0697	spore germination
OM985_08680	COG0523	cobalamin synthesis protein
OM985_08685	COG0701	Predicted permease
OM985_08695	COG0438	transferase activity, transferring glycosyl groups
OM985_08695	COG1216	Glycosyl transferase, family 2
OM985_08700	COG1757	Na H antiporter
OM985_08705	COG0114	fumarate hydratase activity
OM985_08730	COG3340	Belongs to the peptidase S51 family
OM985_08750	COG0785	Cytochrome C biogenesis protein
OM985_08780	COG2733	membrane
OM985_08815	COG1131	(ABC) transporter
OM985_08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM985_08835	COG0528	UMP kinase activity
OM985_08845	COG1027	Aspartate ammonia-lyase
OM985_08850	COG0281	malic enzyme
OM985_08855	COG4191	Histidine kinase
OM985_08860	COG0784	Response regulator, receiver
OM985_08865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM985_08925	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM985_08935	COG2814	Major facilitator Superfamily
OM985_08950	COG1966	Carbon starvation protein
OM985_08965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_08975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM985_08985	COG2223	nitrite transmembrane transporter activity
OM985_08990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM985_09005	COG2244	polysaccharide biosynthetic process
OM985_09010	COG0733	neurotransmitter:sodium symporter activity
OM985_09020	COG5566	PFAM Mor transcription activator
OM985_09025	COG2323	membrane
OM985_09040	COG2084	Dehydrogenase
OM985_09055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM985_09065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM985_09070	COG0028	Belongs to the TPP enzyme family
OM985_09075	COG0440	acetolactate synthase activity
OM985_09080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OM985_09090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM985_09115	COG2814	Major facilitator Superfamily
OM985_09120	COG3384	dioxygenase
OM985_09130	COG3279	Response regulator of the LytR AlgR family
OM985_09135	COG0427	acetyl-CoA hydrolase
OM985_09155	COG1073	alpha beta
OM985_09185	COG0535	radical SAM domain protein
OM985_09190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_09210	COG1914	H( )-stimulated, divalent metal cation uptake system
OM985_09225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM985_09260	COG2390	Transcriptional regulator
OM985_09270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_09275	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OM985_09290	COG4224	UPF0291 protein
OM985_09310	COG0006	proline dipeptidase activity
OM985_09315	COG2132	Multicopper oxidase
OM985_09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM985_09345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM985_09360	COG2372	response to copper ion
OM985_09360	COG1276	copper resistance
OM985_09365	COG4549	nuclear export factor GLE1
OM985_09375	COG0697	spore germination
OM985_09380	COG0583	DNA-binding transcription factor activity
OM985_09385	COG1959	2 iron, 2 sulfur cluster binding
OM985_09390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM985_09395	COG0778	Nitroreductase
OM985_09410	COG0628	permease
OM985_09420	COG1231	oxidoreductase activity
OM985_09425	COG0523	cobalamin synthesis protein
OM985_09440	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_09445	COG2030	dehydratase
OM985_09450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_09460	COG0411	ABC transporter
OM985_09480	COG0583	DNA-binding transcription factor activity
OM985_09490	COG1942	4-Oxalocrotonate Tautomerase
OM985_09500	COG1846	Transcriptional regulator
OM985_09510	COG1271	oxidase subunit
OM985_09515	COG1294	oxidase, subunit
OM985_09520	COG4988	ABC transporter
OM985_09525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM985_09545	COG1686	Belongs to the peptidase S11 family
OM985_09560	COG0791	NLP P60 protein
OM985_09560	COG1388	LysM domain
OM985_09575	COG0745	RESPONSE REGULATOR receiver
OM985_09580	COG5002	protein histidine kinase activity
OM985_09590	COG0300	oxidoreductase activity
OM985_09625	COG0460	homoserine dehydrogenase
OM985_09650	COG1316	TRANSCRIPTIONal
OM985_09660	COG0745	RESPONSE REGULATOR receiver
OM985_09665	COG5002	protein histidine kinase activity
OM985_09680	COG1285	pathogenesis
OM985_09685	COG1247	-acetyltransferase
OM985_09705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM985_09715	COG1082	Xylose isomerase domain protein TIM barrel
OM985_09730	COG1279	arginine transmembrane transporter activity
OM985_09740	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM985_09780	COG2002	toxin-antitoxin pair type II binding
OM985_09785	COG1404	Belongs to the peptidase S8 family
OM985_09790	COG0640	Transcriptional regulator
OM985_09795	COG0667	Aldo Keto reductase
OM985_09800	COG2814	Major facilitator Superfamily
OM985_09825	COG0840	transmembrane signaling receptor activity
OM985_09840	COG3949	Membrane
OM985_09845	COG0783	Belongs to the Dps family
OM985_09860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM985_09870	COG1231	oxidoreductase activity
OM985_09880	COG4989	oxidoreductase activity
OM985_09885	COG0523	cobalamin synthesis protein
OM985_09890	COG0456	acetyltransferase
OM985_09950	COG3443	Belongs to the bacterial solute-binding protein 9 family
OM985_09950	COG0803	Belongs to the bacterial solute-binding protein 9 family
OM985_09960	COG0702	epimerase
OM985_09970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OM985_09980	COG4166	transmembrane transport
OM985_09995	COG0406	alpha-ribazole phosphatase activity
OM985_10005	COG5337	Spore coat protein CotH
OM985_10010	COG1051	belongs to the nudix hydrolase family
OM985_10015	COG0586	Pfam SNARE associated Golgi protein
OM985_10020	COG2244	polysaccharide biosynthetic process
OM985_10030	COG0701	Predicted permease
OM985_10035	COG3689	TIGRFAM TIGR03943 family protein
OM985_10040	COG1607	acyl-coa hydrolase
OM985_10065	COG0702	epimerase
OM985_10070	COG2839	Protein conserved in bacteria
OM985_10075	COG1253	flavin adenine dinucleotide binding
OM985_10090	COG1114	Component of the transport system for branched-chain amino acids
OM985_10095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM985_10115	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM985_10125	COG1876	peptidase activity
OM985_10135	COG0154	amidase activity
OM985_10140	COG2211	Major facilitator Superfamily
OM985_10160	COG0561	phosphatase activity
OM985_10170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM985_10175	COG4106	trans-aconitate 2-methyltransferase activity
OM985_10190	COG1819	glycosyl
OM985_10195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_10200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_10235	COG0456	acetyltransferase
OM985_10290	COG3874	Sporulation protein YtfJ
OM985_10315	COG2226	methyltransferase
OM985_10340	COG0346	lactoylglutathione lyase activity
OM985_10350	COG0604	alcohol dehydrogenase
OM985_10355	COG1595	DNA-templated transcription, initiation
OM985_10380	COG0386	Belongs to the glutathione peroxidase family
OM985_10385	COG1305	Transglutaminase-like
OM985_10390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OM985_10395	COG0714	Associated with various cellular activities
OM985_10410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OM985_10415	COG1140	nitrate reductase beta subunit
OM985_10420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OM985_10425	COG2181	nitrate reductase activity
OM985_10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM985_10450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OM985_10455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM985_10460	COG0303	'Molybdopterin
OM985_10465	COG0314	molybdopterin synthase activity
OM985_10475	COG2223	nitrite transmembrane transporter activity
OM985_10490	COG1648	precorrin-2 dehydrogenase activity
OM985_10500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM985_10500	COG1587	Uroporphyrinogen-III synthase
OM985_10505	COG2146	nitrite reductase [NAD(P)H] activity
OM985_10510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM985_10515	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
OM985_10550	COG2359	stage V sporulation protein S
OM985_10575	COG1418	mRNA catabolic process
OM985_10580	COG0488	(ABC) transporter
OM985_10595	COG0629	single-stranded DNA binding
OM985_10610	COG1413	lyase activity
OM985_10625	COG2136	Putative SAM-dependent methyltransferase
OM985_10625	COG2521	methyltransferase
OM985_10630	COG0018	arginyl-trna synthetase
OM985_10655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM985_10675	COG0017	Asparaginyl-tRNA synthetase
OM985_10695	COG1674	ftsk spoiiie
OM985_10765	COG1929	Belongs to the glycerate kinase type-1 family
OM985_10770	COG0471	metal ion transport
OM985_10775	COG0745	RESPONSE REGULATOR receiver
OM985_10780	COG5002	protein histidine kinase activity
OM985_10780	COG3850	Histidine kinase
OM985_10795	COG0733	neurotransmitter:sodium symporter activity
OM985_10820	COG2610	gluconate transmembrane transporter activity
OM985_10825	COG1454	alcohol dehydrogenase
OM985_10830	COG1794	racemase activity, acting on amino acids and derivatives
OM985_10840	COG0456	acetyltransferase
OM985_10855	COG1131	(ABC) transporter
OM985_10870	COG0546	phosphoglycolate phosphatase activity
OM985_10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM985_10905	COG0768	penicillin binding
OM985_10910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM985_10915	COG0204	Acyl-transferase
OM985_10920	COG1272	protein, Hemolysin III
OM985_10930	COG0805	protein transport
OM985_10940	COG1307	EDD domain protein, DegV family
OM985_10945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OM985_10950	COG1999	signal sequence binding
OM985_10955	COG0071	Belongs to the small heat shock protein (HSP20) family
OM985_10960	COG0367	asparagine synthase
OM985_10975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_10980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM985_11015	COG0668	transmembrane transport
OM985_11020	COG4585	Histidine kinase
OM985_11020	COG2203	Gaf domain
OM985_11025	COG2197	response regulator
OM985_11035	COG1064	alcohol dehydrogenase
OM985_11090	COG1125	glycine betaine transport
OM985_11090	COG0517	IMP dehydrogenase activity
OM985_11095	COG1174	glycine betaine transport
OM985_11130	COG1253	flavin adenine dinucleotide binding
OM985_11135	COG1012	belongs to the aldehyde dehydrogenase family
OM985_11140	COG5506	Protein of unknown function (DUF1694)
OM985_11155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM985_11160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM985_11165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OM985_11170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM985_11175	COG0456	acetyltransferase
OM985_11180	COG3829	transcription factor binding
OM985_11185	COG1509	lysine 2,3-aminomutase activity
OM985_11225	COG4326	sporulation control protein
OM985_11230	COG0671	phosphoesterase, PA-phosphatase related
OM985_11235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM985_11240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM985_11270	COG1787	Restriction endonuclease
OM985_11270	COG1715	Restriction endonuclease
OM985_11365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM985_11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM985_11405	COG4499	WXG100 protein secretion system (Wss), protein YukC
OM985_11415	COG2814	Major facilitator Superfamily
OM985_11420	COG4841	protein insertion into membrane
OM985_11425	COG0372	Belongs to the citrate synthase family
OM985_11430	COG2079	MmgE PrpD family protein
OM985_11435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OM985_11440	COG1960	acyl-CoA dehydrogenase activity
OM985_11445	COG2084	Dehydrogenase
OM985_11455	COG1280	lysine exporter protein (LysE YggA)
OM985_11460	COG1024	Enoyl-CoA hydratase
OM985_11475	COG0420	3'-5' exonuclease activity
OM985_11480	COG0419	ATPase involved in DNA repair
OM985_11505	COG2223	nitrite transmembrane transporter activity
OM985_11510	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_11515	COG1169	isochorismate synthase
OM985_11520	COG1021	2,3-dihydroxybenzoate-AMP ligase
OM985_11525	COG3433	isochorismatase activity
OM985_11525	COG1535	isochorismatase
OM985_11530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM985_11535	COG3251	PFAM MbtH domain protein
OM985_11540	COG2814	Major facilitator Superfamily
OM985_11555	COG0776	regulation of translation
OM985_11565	COG2318	DinB family
OM985_11575	COG1115	amino acid carrier protein
OM985_11590	COG2329	Antibiotic biosynthesis monooxygenase
OM985_11595	COG1187	pseudouridine synthase activity
OM985_11600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM985_11615	COG0596	Alpha beta hydrolase
OM985_11620	COG2814	Major facilitator Superfamily
OM985_11640	COG2226	methyltransferase
OM985_11685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_11720	COG1247	-acetyltransferase
OM985_11750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OM985_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_11770	COG1278	Cold shock
OM985_11785	COG0010	Belongs to the arginase family
OM985_11790	COG0561	phosphatase activity
OM985_11835	COG0583	DNA-binding transcription factor activity
OM985_11840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM985_11855	COG0583	DNA-binding transcription factor activity
OM985_11860	COG2258	MOSC domain
OM985_11875	COG1132	(ABC) transporter
OM985_11880	COG1132	(ABC) transporter
OM985_11900	COG1396	sequence-specific DNA binding
OM985_11925	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
OM985_11930	COG1595	DNA-templated transcription, initiation
OM985_11955	COG1649	PFAM Uncharacterised BCR, COG1649
OM985_11980	COG2971	BadF BadG BcrA BcrD
OM985_11985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OM985_11990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM985_12010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_12040	COG1309	transcriptional regulator
OM985_12055	COG1136	(ABC) transporter
OM985_12055	COG0577	efflux transmembrane transporter activity
OM985_12060	COG0500	methyltransferase
OM985_12060	COG3615	Tellurite resistance protein tehB
OM985_12070	COG2226	methyltransferase
OM985_12075	COG3961	Belongs to the TPP enzyme family
OM985_12080	COG1846	Transcriptional regulator
OM985_12125	COG2195	Cleaves the N-terminal amino acid of tripeptides
OM985_12140	COG1595	DNA-templated transcription, initiation
OM985_12160	COG2367	Beta-lactamase
OM985_12165	COG0671	phosphoesterase, PA-phosphatase related
OM985_12170	COG1609	Transcriptional regulator
OM985_12175	COG2814	Major facilitator Superfamily
OM985_12180	COG0673	inositol 2-dehydrogenase activity
OM985_12190	COG1012	belongs to the aldehyde dehydrogenase family
OM985_12205	COG0191	fructose-bisphosphate aldolase activity
OM985_12210	COG3718	enzyme involved in inositol metabolism
OM985_12235	COG0457	Tetratricopeptide repeat
OM985_12240	COG1476	TRANSCRIPTIONal
OM985_12255	COG1876	peptidase activity
OM985_12275	COG1309	transcriptional regulator
OM985_12280	COG0488	(ABC) transporter
OM985_12295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_12310	COG1252	NADH dehydrogenase
OM985_12315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM985_12330	COG1131	(ABC) transporter
OM985_12340	COG1309	transcriptional regulator
OM985_12355	COG1960	acyl-CoA dehydrogenase activity
OM985_12360	COG0439	Biotin carboxylase
OM985_12365	COG0511	ligase activity, forming carbon-carbon bonds
OM985_12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM985_12375	COG1024	Enoyl-CoA hydratase
OM985_12380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM985_12385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM985_12395	COG1247	-acetyltransferase
OM985_12400	COG0572	uridine kinase
OM985_12410	COG2318	DinB family
OM985_12440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OM985_12480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM985_12480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM985_12505	COG2814	Major facilitator Superfamily
OM985_12525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM985_12545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_12560	COG1063	alcohol dehydrogenase
OM985_12575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM985_12580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM985_12595	COG3773	Cell wall hydrolase
OM985_12605	COG0745	RESPONSE REGULATOR receiver
OM985_12660	COG0460	homoserine dehydrogenase
OM985_12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OM985_12745	COG2124	cytochrome p450
OM985_12780	COG0561	phosphatase activity
OM985_12790	COG0768	penicillin binding
OM985_12795	COG1819	glycosyl
OM985_12800	COG1794	racemase activity, acting on amino acids and derivatives
OM985_12810	COG1122	ATPase activity
OM985_12825	COG2205	protein histidine kinase activity
OM985_12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OM985_12840	COG0604	alcohol dehydrogenase
OM985_12845	COG0768	penicillin binding
OM985_12855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM985_12890	COG0693	protein deglycase activity
OM985_12920	COG2814	Major facilitator Superfamily
OM985_12935	COG0584	glycerophosphoryl diester phosphodiesterase
OM985_12955	COG0697	spore germination
OM985_12995	COG2223	nitrite transmembrane transporter activity
OM985_13010	COG2816	NAD+ diphosphatase activity
OM985_13015	COG0592	DNA-directed DNA polymerase activity
OM985_13020	COG1051	belongs to the nudix hydrolase family
OM985_13055	COG3878	Protein conserved in bacteria
OM985_13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM985_13120	COG0322	excinuclease ABC activity
OM985_13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM985_13185	COG1011	Hydrolase
OM985_13205	COG0076	glutamate decarboxylase activity
OM985_13220	COG1523	belongs to the glycosyl hydrolase 13 family
OM985_13225	COG3227	Zinc metalloprotease (Elastase)
OM985_13245	COG0201	protein transport
OM985_13255	COG0697	spore germination
OM985_13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_13290	COG4129	membrane
OM985_13295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_13310	COG2959	enzyme of heme biosynthesis
OM985_13330	COG3483	tryptophan 2,3-dioxygenase activity
OM985_13335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OM985_13340	COG3844	kynureninase activity
OM985_13345	COG1309	transcriptional regulator
OM985_13375	COG3284	Transcriptional regulator
OM985_13395	COG1349	DNA-binding transcription factor activity
OM985_13415	COG1959	2 iron, 2 sulfur cluster binding
OM985_13430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM985_13435	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM985_13440	COG0022	dehydrogenase e1 component
OM985_13445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM985_13455	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_13460	COG0456	acetyltransferase
OM985_13460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OM985_13490	COG4176	ABC-type proline glycine betaine transport system permease component
OM985_13495	COG4175	Glycine betaine
OM985_13495	COG0517	IMP dehydrogenase activity
OM985_13520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OM985_13525	COG2153	protein acetylation
OM985_13530	COG3397	chitin binding
OM985_13545	COG2205	protein histidine kinase activity
OM985_13575	COG0658	competence protein
OM985_13575	COG2333	competence protein COMEC
OM985_13625	COG3973	AAA domain
OM985_13640	COG2105	PFAM AIG2 family protein
OM985_13645	COG0514	ATP-dependent DNA helicase (RecQ)
OM985_13665	COG4637	Psort location Cytoplasmic, score
OM985_13690	COG3397	chitin binding
OM985_13705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM985_13710	COG1115	amino acid carrier protein
OM985_13715	COG1012	belongs to the aldehyde dehydrogenase family
OM985_13720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OM985_13730	COG3938	Belongs to the proline racemase family
OM985_13735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM985_13775	COG0586	Pfam SNARE associated Golgi protein
OM985_13790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OM985_13795	COG0519	Catalyzes the synthesis of GMP from XMP
OM985_13800	COG4166	transmembrane transport
OM985_13810	COG4948	Mandelate Racemase Muconate Lactonizing
OM985_13855	COG2936	dipeptidyl-peptidase activity
OM985_13860	COG5002	protein histidine kinase activity
OM985_13910	COG1307	EDD domain protein, DegV family
OM985_13930	COG2814	Major facilitator Superfamily
OM985_13940	COG1664	Polymer-forming cytoskeletal
OM985_13945	COG0789	Transcriptional regulator
OM985_13950	COG4533	DNA binding
OM985_13955	COG2814	Major facilitator Superfamily
OM985_13955	COG0477	Major facilitator Superfamily
OM985_13975	COG2261	transglycosylase associated protein
OM985_13990	COG2226	methyltransferase
OM985_14025	COG0436	Aminotransferase
OM985_14030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM985_14035	COG5146	pantothenate kinase activity
OM985_14100	COG0628	permease
OM985_14115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM985_14120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM985_14125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM985_14130	COG1116	anion transmembrane transporter activity
OM985_14150	COG2816	NAD+ diphosphatase activity
OM985_14195	COG0697	spore germination
OM985_14200	COG2318	DinB family
OM985_14220	COG4912	Dna alkylation repair
OM985_14240	COG0861	Integral membrane protein TerC family
OM985_14245	COG1368	sulfuric ester hydrolase activity
OM985_14250	COG0488	(ABC) transporter
OM985_14265	COG1309	transcriptional regulator
OM985_14280	COG0287	Prephenate dehydrogenase
OM985_14285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OM985_14290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OM985_14295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OM985_14295	COG1605	Chorismate mutase
OM985_14330	COG1388	LysM domain
OM985_14330	COG3584	3D domain protein
OM985_14340	COG1595	DNA-templated transcription, initiation
OM985_14365	COG1879	ABC-type sugar transport system periplasmic component
OM985_14375	COG1172	Belongs to the binding-protein-dependent transport system permease family
OM985_14385	COG2390	Transcriptional regulator
OM985_14420	COG2329	Antibiotic biosynthesis monooxygenase
OM985_14440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_14450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM985_14455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM985_14460	COG4187	Peptidase family M20/M25/M40
OM985_14465	COG1414	Transcriptional regulator
OM985_14470	COG0833	amino acid
OM985_14475	COG1690	Belongs to the RtcB family
OM985_14485	COG1785	Belongs to the alkaline phosphatase family
OM985_14495	COG3655	Transcriptional regulator
OM985_14510	COG4377	Putative membrane peptidase family (DUF2324)
OM985_14520	COG3279	Response regulator of the LytR AlgR family
OM985_14530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_14535	COG0346	lactoylglutathione lyase activity
OM985_14555	COG0714	Associated with various cellular activities
OM985_14580	COG0463	Glycosyl transferase, family 2
OM985_14600	COG0463	Glycosyl transferase, family 2
OM985_14610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM985_14615	COG0753	catalase activity
OM985_14625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OM985_14650	COG0714	Associated with various cellular activities
OM985_14660	COG0778	Nitroreductase
OM985_14665	COG1846	Transcriptional regulator
OM985_14705	COG1725	Transcriptional regulator
OM985_14715	COG1136	(ABC) transporter
OM985_14715	COG0577	efflux transmembrane transporter activity
OM985_14740	COG2207	Transcriptional regulator
OM985_14745	COG0456	acetyltransferase
OM985_14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_14785	COG0642	Histidine kinase
OM985_14790	COG0745	RESPONSE REGULATOR receiver
OM985_14795	COG0596	Alpha beta hydrolase
OM985_14825	COG0730	response to heat
OM985_14835	COG0833	amino acid
OM985_14845	COG4335	DNA alkylation repair
OM985_14885	COG0768	penicillin binding
OM985_14895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM985_14930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OM985_14935	COG1414	Transcriptional regulator
OM985_14950	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM985_14955	COG0640	Transcriptional regulator
OM985_14965	COG1960	acyl-CoA dehydrogenase activity
OM985_14985	COG3314	Sporulation integral membrane protein YlbJ
OM985_15000	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OM985_15015	COG0574	Belongs to the PEP-utilizing enzyme family
OM985_15015	COG3848	Pyruvate phosphate dikinase
OM985_15020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_15035	COG5577	PFAM Coat F domain
OM985_15040	COG3403	YqcI/YcgG family
OM985_15045	COG1280	lysine exporter protein (LysE YggA)
OM985_15080	COG1063	alcohol dehydrogenase
OM985_15095	COG1027	Aspartate ammonia-lyase
OM985_15100	COG0252	asparaginase activity
OM985_15105	COG1396	sequence-specific DNA binding
OM985_15115	COG0322	excinuclease ABC activity
OM985_15120	COG0531	amino acid
OM985_15125	COG1114	Component of the transport system for branched-chain amino acids
OM985_15130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM985_15140	COG0281	malic enzyme
OM985_15155	COG0531	amino acid
OM985_15165	COG0784	Response regulator, receiver
OM985_15175	COG2066	Belongs to the glutaminase family
OM985_15210	COG0737	Belongs to the 5'-nucleotidase family
OM985_15215	COG0753	catalase activity
OM985_15220	COG2267	carboxylic ester hydrolase activity
OM985_15225	COG1335	isochorismatase
OM985_15245	COG0583	DNA-binding transcription factor activity
OM985_15295	COG0415	Belongs to the DNA photolyase family
OM985_15300	COG0288	reversible hydration of carbon dioxide
OM985_15310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM985_15315	COG5609	conserved protein (DUF2294)
OM985_15330	COG1575	Belongs to the MenA family. Type 1 subfamily
OM985_15335	COG2267	carboxylic ester hydrolase activity
OM985_15340	COG0803	Belongs to the bacterial solute-binding protein 9 family
OM985_15345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OM985_15350	COG1121	(ABC) transporter
OM985_15380	COG0798	PFAM Bile acid sodium symporter
OM985_15385	COG0346	lactoylglutathione lyase activity
OM985_15390	COG0640	Transcriptional regulator
OM985_15405	COG0443	Heat shock 70 kDa protein
OM985_15420	COG1522	sequence-specific DNA binding
OM985_15435	COG0346	lactoylglutathione lyase activity
OM985_15505	COG2814	Major facilitator Superfamily
OM985_15530	COG0745	RESPONSE REGULATOR receiver
OM985_15535	COG3850	Histidine kinase
OM985_15535	COG5002	protein histidine kinase activity
OM985_15560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OM985_15580	COG1476	TRANSCRIPTIONal
OM985_15595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM985_15610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_15615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OM985_15630	COG1136	(ABC) transporter
OM985_15635	COG0577	efflux transmembrane transporter activity
OM985_15650	COG5002	protein histidine kinase activity
OM985_15650	COG3850	Histidine kinase
OM985_15660	COG2364	Membrane
OM985_15665	COG1846	Transcriptional regulator
OM985_15675	COG2808	Putative FMN-binding domain
OM985_15680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_15685	COG2271	Major facilitator Superfamily
OM985_15690	COG1556	Lactate utilization protein
OM985_15695	COG1139	Iron-sulfur cluster binding protein
OM985_15705	COG0583	DNA-binding transcription factor activity
OM985_15715	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM985_15740	COG0738	Major facilitator superfamily
OM985_15745	COG0673	inositol 2-dehydrogenase activity
OM985_15750	COG0561	phosphatase activity
OM985_15760	COG1609	Transcriptional regulator
OM985_15765	COG0457	Tetratricopeptide repeat
OM985_15785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM985_15815	COG0534	Mate efflux family protein
OM985_15840	COG2814	Major facilitator Superfamily
OM985_15845	COG1309	transcriptional regulator
OM985_15860	COG0814	amino acid
OM985_15865	COG1760	l-serine dehydratase
OM985_15870	COG1760	l-serine dehydratase
OM985_15880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OM985_15885	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
OM985_15895	COG1335	isochorismatase
OM985_15900	COG1522	sequence-specific DNA binding
OM985_15905	COG0531	amino acid
OM985_15925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM985_15945	COG1595	DNA-templated transcription, initiation
OM985_15960	COG0662	Cupin 2, conserved barrel domain protein
OM985_15965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_15965	COG2207	Transcriptional regulator
OM985_16020	COG0477	Major facilitator Superfamily
OM985_16030	COG1846	Transcriptional regulator
OM985_16035	COG2814	Major facilitator Superfamily
OM985_16045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM985_16050	COG1131	(ABC) transporter
OM985_16070	COG2076	Multidrug Resistance protein
OM985_16075	COG1309	transcriptional regulator
OM985_16085	COG2031	fatty acid transporter
OM985_16095	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM985_16125	COG1122	ATPase activity
OM985_16130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OM985_16145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OM985_16150	COG1288	antiporter activity
OM985_16155	COG2356	endonuclease I
OM985_16170	COG3620	sequence-specific DNA binding
OM985_16175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OM985_16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM985_16185	COG0124	histidyl-tRNA synthetase
OM985_16200	COG1733	regulation of RNA biosynthetic process
OM985_16205	COG0778	Nitroreductase
OM985_16225	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_16235	COG1131	(ABC) transporter
OM985_16260	COG1011	Hydrolase
OM985_16270	COG2365	Tyrosine phosphatase family
OM985_16295	COG0346	lactoylglutathione lyase activity
OM985_16300	COG1940	carbohydrate kinase activity
OM985_16305	COG0738	Major facilitator superfamily
OM985_16310	COG0110	maltose O-acetyltransferase activity
OM985_16320	COG0577	efflux transmembrane transporter activity
OM985_16320	COG1136	(ABC) transporter
OM985_16335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OM985_16340	COG0628	permease
OM985_16360	COG2226	methyltransferase
OM985_16370	COG0477	Major facilitator Superfamily
OM985_16400	COG1253	flavin adenine dinucleotide binding
OM985_16405	COG0789	Transcriptional regulator
OM985_16410	COG0697	spore germination
OM985_16415	COG1357	PFAM Pentapeptide repeats (8 copies)
OM985_16420	COG3813	Protein conserved in bacteria
OM985_16425	COG2706	6-phosphogluconolactonase activity
OM985_16430	COG1070	Carbohydrate kinase
OM985_16440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OM985_16445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OM985_16455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM985_16460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM985_16465	COG0604	alcohol dehydrogenase
OM985_16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM985_16480	COG0604	alcohol dehydrogenase
OM985_16480	COG3321	synthase
OM985_16485	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_16510	COG0656	L-ascorbic acid biosynthetic process
OM985_16515	COG2814	Major facilitator Superfamily
OM985_16530	COG0346	lactoylglutathione lyase activity
OM985_16535	COG0814	amino acid
OM985_16560	COG1393	Belongs to the ArsC family
OM985_16565	COG1733	regulation of RNA biosynthetic process
OM985_16570	COG2188	Transcriptional regulator
OM985_16580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OM985_16585	COG1733	regulation of RNA biosynthetic process
OM985_16590	COG1733	regulation of RNA biosynthetic process
OM985_16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_16625	COG0384	phenazine biosynthesis protein PhzF
OM985_16635	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_16645	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_16655	COG1733	regulation of RNA biosynthetic process
OM985_16685	COG1191	sigma factor activity
OM985_16700	COG1309	transcriptional regulator
OM985_16720	COG3152	Membrane
OM985_16745	COG1151	hydroxylamine reductase activity
OM985_16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_16760	COG3409	Peptidoglycan-binding domain 1 protein
OM985_16760	COG3757	hydrolase, family 25
OM985_16795	COG2072	flavoprotein involved in K transport
OM985_16835	COG1113	amino acid transport
OM985_16840	COG2814	Major facilitator Superfamily
OM985_16870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM985_16875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OM985_16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_16910	COG3739	integral membrane protein
OM985_16915	COG0384	phenazine biosynthesis protein PhzF
OM985_16945	COG0583	DNA-binding transcription factor activity
OM985_16965	COG1193	negative regulation of DNA recombination
OM985_16985	COG1164	Oligoendopeptidase f
OM985_16990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM985_17020	COG0584	glycerophosphoryl diester phosphodiesterase
OM985_17045	COG0640	Transcriptional regulator
OM985_17050	COG0604	alcohol dehydrogenase
OM985_17070	COG2808	Putative FMN-binding domain
OM985_17075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OM985_17085	COG0385	Bile acid
OM985_17090	COG0277	FAD linked oxidase domain protein
OM985_17120	COG1216	Glycosyl transferase, family 2
OM985_17125	COG1024	Enoyl-CoA hydratase
OM985_17135	COG1285	pathogenesis
OM985_17150	COG2514	catechol 2,3-dioxygenase activity
OM985_17155	COG2720	vancomycin resistance protein
OM985_17195	COG0716	FMN binding
OM985_17225	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_17235	COG0165	Argininosuccinate lyase
OM985_17250	COG4145	pantothenate transmembrane transporter activity
OM985_17260	COG1012	belongs to the aldehyde dehydrogenase family
OM985_17265	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_17275	COG1657	PFAM Prenyltransferase squalene oxidase
OM985_17280	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OM985_17285	COG2962	Rard protein
OM985_17290	COG3326	Membrane
OM985_17305	COG0489	protein tyrosine kinase activity
OM985_17315	COG0314	molybdopterin synthase activity
OM985_17320	COG0303	'Molybdopterin
OM985_17325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM985_17330	COG2116	formate transmembrane transporter activity
OM985_17340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM985_17345	COG5609	conserved protein (DUF2294)
OM985_17350	COG2427	Protein of unknown function (DUF1641)
OM985_17355	COG3383	formate dehydrogenase (NAD+) activity
OM985_17365	COG0697	spore germination
OM985_17405	COG2226	methyltransferase
OM985_17410	COG4166	transmembrane transport
OM985_17415	COG4166	transmembrane transport
OM985_17420	COG4166	transmembrane transport
OM985_17425	COG1301	dicarboxylic acid transport
OM985_17430	COG1316	TRANSCRIPTIONal
OM985_17440	COG1595	DNA-templated transcription, initiation
OM985_17455	COG1131	(ABC) transporter
OM985_17465	COG0673	inositol 2-dehydrogenase activity
OM985_17470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OM985_17475	COG0187	DNA topoisomerase II activity
OM985_17480	COG1832	CoA-binding protein
OM985_17485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM985_17490	COG0745	RESPONSE REGULATOR receiver
OM985_17505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OM985_17510	COG4841	protein insertion into membrane
OM985_17515	COG0824	Thioesterase
OM985_17545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM985_17555	COG2274	protein secretion by the type I secretion system
OM985_17560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OM985_17600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM985_17615	COG0183	Belongs to the thiolase family
OM985_17620	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_17625	COG1268	BioY protein
OM985_17630	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_17680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_17690	COG5002	protein histidine kinase activity
OM985_17695	COG0400	carboxylic ester hydrolase activity
OM985_17700	COG0346	lactoylglutathione lyase activity
OM985_17705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM985_17710	COG0069	glutamate synthase activity
OM985_17715	COG1902	pentaerythritol trinitrate reductase activity
OM985_17720	COG1329	Transcriptional regulator
OM985_17725	COG0010	Belongs to the arginase family
OM985_17750	COG2226	methyltransferase
OM985_17785	COG4846	Membrane protein involved in cytochrome C biogenesis
OM985_17790	COG0785	Cytochrome C biogenesis protein
OM985_17800	COG0583	DNA-binding transcription factor activity
OM985_17805	COG1380	Effector of murein hydrolase LrgA
OM985_17810	COG1346	cytolysis
OM985_17835	COG3409	Peptidoglycan-binding domain 1 protein
OM985_17835	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM985_17850	COG1132	(ABC) transporter
OM985_17855	COG1132	(ABC) transporter
OM985_17885	COG3639	organic phosphonate transmembrane transporter activity
OM985_17890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OM985_17910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM985_17930	COG1695	Transcriptional regulator
OM985_17975	COG1388	LysM domain
OM985_17975	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM985_17975	COG3409	Peptidoglycan-binding domain 1 protein
OM985_17980	COG4824	toxin secretion phage lysis holin
OM985_18140	COG1595	DNA-templated transcription, initiation
OM985_18185	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OM985_18270	COG1396	sequence-specific DNA binding
OM985_18295	COG0174	glutamine synthetase
OM985_18300	COG0789	Transcriptional regulator
OM985_18305	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OM985_18315	COG2860	membrane
OM985_18320	COG0464	growth
OM985_18350	COG1388	LysM domain
OM985_18350	COG3584	3D domain protein
OM985_18355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM985_18355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM985_18355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM985_18360	COG1105	Belongs to the carbohydrate kinase PfkB family
OM985_18365	COG1349	DNA-binding transcription factor activity
OM985_18375	COG2322	membrane
OM985_18385	COG1113	amino acid transport
OM985_18400	COG1408	metallophosphoesterase
OM985_18405	COG2116	formate transmembrane transporter activity
OM985_18415	COG2217	Heavy metal translocating P-type atpase
OM985_18420	COG2608	mercury ion transmembrane transporter activity
OM985_18425	COG1937	Protein conserved in bacteria
OM985_18435	COG2819	hydrolase of the alpha beta superfamily
OM985_18440	COG1120	ATPase activity
OM985_18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_18460	COG0708	Exodeoxyribonuclease III
OM985_18465	COG2169	Transcriptional regulator
OM985_18470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OM985_18475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM985_18485	COG2364	Membrane
OM985_18500	COG2267	carboxylic ester hydrolase activity
OM985_18505	COG0346	lactoylglutathione lyase activity
OM985_18510	COG5001	Diguanylate cyclase
OM985_18510	COG3300	MHYT domain
OM985_18525	COG1346	cytolysis
OM985_18530	COG1380	Effector of murein hydrolase LrgA
OM985_18535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM985_18540	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM985_18540	COG0596	Alpha beta hydrolase
OM985_18545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM985_18565	COG1404	Belongs to the peptidase S8 family
OM985_18570	COG3773	Cell wall hydrolase
OM985_18575	COG0562	UDP-galactopyranose mutase
OM985_18580	COG1368	sulfuric ester hydrolase activity
OM985_18585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OM985_18595	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OM985_18620	COG1131	(ABC) transporter
OM985_18640	COG4550	Control of competence regulator ComK, YlbF/YmcA
OM985_18645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM985_18650	COG1013	pyruvate-flavodoxin oxidoreductase activity
OM985_18655	COG0674	pyruvate-flavodoxin oxidoreductase activity
OM985_18655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OM985_18665	COG2359	stage V sporulation protein S
OM985_18670	COG1692	metallophosphoesterase
OM985_18695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM985_18700	COG1426	Protein conserved in bacteria
OM985_18715	COG0300	oxidoreductase activity
OM985_18720	COG0612	Peptidase, M16
OM985_18725	COG0612	Peptidase, M16
OM985_18740	COG3845	ABC transporter
OM985_18745	COG1744	ABC transporter substrate-binding protein PnrA-like
OM985_18750	COG2188	Transcriptional regulator
OM985_18755	COG1674	ftsk spoiiie
OM985_18765	COG0740	serine-type endopeptidase activity
OM985_18770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OM985_18780	COG0527	aspartate kinase activity
OM985_18785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM985_18790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM985_18795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM985_18800	COG1873	PFAM PRC-barrel domain
OM985_18805	COG0612	Peptidase, M16
OM985_18810	COG0726	polysaccharide deacetylase
OM985_18825	COG0196	riboflavin kinase activity
OM985_18830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OM985_18840	COG1550	Protein conserved in bacteria
OM985_18850	COG1358	cellular component organization or biogenesis
OM985_18855	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OM985_18860	COG0195	Participates in both transcription termination and antitermination
OM985_18880	COG0750	zinc metalloprotease
OM985_18890	COG4589	Belongs to the CDS family
OM985_18895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM985_18905	COG0528	UMP kinase activity
OM985_18935	COG4974	Belongs to the 'phage' integrase family
OM985_18945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM985_18955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM985_18995	COG1837	Belongs to the UPF0109 family
OM985_19005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM985_19015	COG0552	protein localization to endoplasmic reticulum
OM985_19020	COG1196	nuclear chromosome segregation
OM985_19030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM985_19035	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_19040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM985_19055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM985_19060	COG1461	Dihydroxyacetone kinase
OM985_19065	COG1302	Protein conserved in bacteria
OM985_19080	COG1564	THIamine pyrophosphokinase
OM985_19085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OM985_19090	COG1162	GTPase activity
OM985_19095	COG0515	serine threonine protein kinase
OM985_19095	COG2815	serine threonine protein kinase
OM985_19100	COG0631	protein serine/threonine phosphatase activity
OM985_19110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM985_19110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM985_19120	COG0242	peptide deformylase activity
OM985_19125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM985_19130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM985_19150	COG1561	YicC-like family, N-terminal region
OM985_19155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OM985_19165	COG0006	proline dipeptidase activity
OM985_19180	COG3069	C4-dicarboxylate transmembrane transporter activity
OM985_19245	COG0564	pseudouridine synthase activity
OM985_19265	COG3599	regulation of cell shape
OM985_19270	COG2302	S4 RNA-binding domain
OM985_19275	COG0762	integral membrane protein
OM985_19285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM985_19290	COG1496	oxidoreductase activity
OM985_19295	COG1873	PFAM PRC-barrel domain
OM985_19300	COG1191	sigma factor activity
OM985_19305	COG1191	sigma factor activity
OM985_19315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OM985_19320	COG0849	cell division
OM985_19325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM985_19330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM985_19340	COG0772	Belongs to the SEDS family
OM985_19355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OM985_19360	COG0768	penicillin binding
OM985_19365	COG0768	penicillin binding
OM985_19370	COG4839	cell division protein FtsL
OM985_19385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM985_19400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OM985_19405	COG1399	metal-binding, possibly nucleic acid-binding protein
OM985_19455	COG4824	toxin secretion phage lysis holin
OM985_19555	COG1802	Transcriptional regulator
OM985_19555	COG4626	Terminase
OM985_19580	COG0582	viral genome integration into host DNA
OM985_19645	COG0756	dUTP diphosphatase activity
OM985_19660	COG1191	sigma factor activity
OM985_19685	COG1484	DNA-dependent DNA replication
OM985_19715	COG1396	sequence-specific DNA binding
OM985_19730	COG1396	sequence-specific DNA binding
OM985_19750	COG0582	viral genome integration into host DNA
OM985_19760	COG3480	Lon protease (S16) C-terminal proteolytic domain
OM985_19765	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM985_19770	COG3314	Sporulation integral membrane protein YlbJ
OM985_19780	COG0742	ribosomal rna small subunit methyltransferase
OM985_19795	COG3679	Belongs to the UPF0342 family
OM985_19800	COG0406	alpha-ribazole phosphatase activity
OM985_19815	COG2340	Cysteine-rich secretory protein family
OM985_19830	COG3336	cytochrome c oxidase
OM985_19865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OM985_19870	COG0772	Belongs to the SEDS family
OM985_19880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM985_19885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM985_19895	COG4896	Protein conserved in bacteria
OM985_19910	COG1217	gtp-binding protein TYPA
OM985_19920	COG0483	inositol monophosphate 1-phosphatase activity
OM985_19940	COG1982	Orn Lys Arg decarboxylase major
OM985_19985	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM985_19990	COG0022	dehydrogenase e1 component
OM985_19995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM985_20005	COG0242	peptide deformylase activity
OM985_20010	COG0561	phosphatase activity
OM985_20020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OM985_20025	COG0569	domain protein
OM985_20045	COG0583	DNA-binding transcription factor activity
OM985_20050	COG0517	IMP dehydrogenase activity
OM985_20060	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OM985_20070	COG4703	Protein of unknown function (DUF1797)
OM985_20085	COG2200	EAL domain
OM985_20090	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_20095	COG1408	metallophosphoesterase
OM985_20105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OM985_20140	COG2814	Major facilitator Superfamily
OM985_20160	COG3209	COG3209 Rhs family protein
OM985_20170	COG2205	protein histidine kinase activity
OM985_20180	COG0436	Aminotransferase
OM985_20185	COG1609	Transcriptional regulator
OM985_20190	COG3833	ABC-type maltose transport systems, permease component
OM985_20195	COG1175	transmembrane transport
OM985_20200	COG2182	Extracellular solute-binding protein
OM985_20210	COG0366	Alpha amylase catalytic
OM985_20215	COG3842	ATPase activity
OM985_20255	COG0183	Belongs to the thiolase family
OM985_20290	COG1695	Transcriptional regulator
OM985_20295	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_20305	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OM985_20315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM985_20320	COG0436	Aminotransferase
OM985_20340	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OM985_20360	COG2199	diguanylate cyclase activity
OM985_20365	COG0778	Nitroreductase
OM985_20390	COG1263	PTS System
OM985_20390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM985_20390	COG2190	(PTS) system
OM985_20395	COG3711	transcriptional antiterminator
OM985_20405	COG2188	Transcriptional regulator
OM985_20415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM985_20440	COG1547	Domain of unknown function (DUF309)
OM985_20445	COG0456	acetyltransferase
OM985_20455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM985_20460	COG4086	secreted protein
OM985_20465	COG0561	phosphatase activity
OM985_20470	COG0697	spore germination
OM985_20485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_20510	COG0733	neurotransmitter:sodium symporter activity
OM985_20530	COG1686	Belongs to the peptidase S11 family
OM985_20535	COG1725	Transcriptional regulator
OM985_20540	COG1131	(ABC) transporter
OM985_20555	COG1846	Transcriptional regulator
OM985_20570	COG0598	Magnesium transport protein CorA
OM985_20595	COG4974	Belongs to the 'phage' integrase family
OM985_20605	COG0735	belongs to the Fur family
OM985_20610	COG1300	Membrane
OM985_20630	COG0667	Aldo Keto reductase
OM985_20635	COG0656	L-ascorbic acid biosynthetic process
OM985_20640	COG0456	acetyltransferase
OM985_20640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OM985_20650	COG0737	Belongs to the 5'-nucleotidase family
OM985_20650	COG1525	nuclease
OM985_20650	COG4085	toxin activity
OM985_20660	COG0596	Alpha beta hydrolase
OM985_20665	COG2056	Na+-H+ antiporter family
OM985_20670	COG1609	Transcriptional regulator
OM985_20675	COG0456	acetyltransferase
OM985_20680	COG1073	alpha beta
OM985_20695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM985_20695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM985_20700	COG0307	riboflavin synthase, alpha
OM985_20725	COG4106	trans-aconitate 2-methyltransferase activity
OM985_20730	COG1073	alpha beta
OM985_20730	COG2226	methyltransferase
OM985_20745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM985_20755	COG1757	Na H antiporter
OM985_20760	COG0737	Belongs to the 5'-nucleotidase family
OM985_20770	COG1522	sequence-specific DNA binding
OM985_20790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM985_20800	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OM985_20815	COG0300	oxidoreductase activity
OM985_20825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM985_20830	COG1760	l-serine dehydratase
OM985_20835	COG1760	l-serine dehydratase
OM985_20855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM985_20865	COG2195	Cleaves the N-terminal amino acid of tripeptides
OM985_20870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_20885	COG1376	ErfK ybiS ycfS ynhG family protein
OM985_20890	COG4129	membrane
OM985_20895	COG1126	abc transporter atp-binding protein
OM985_20900	COG0765	amino acid transport
OM985_20905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM985_20920	COG2816	NAD+ diphosphatase activity
OM985_20925	COG0772	Belongs to the SEDS family
OM985_20930	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM985_20935	COG0022	dehydrogenase e1 component
OM985_20940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM985_20945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM985_20960	COG0280	phosphate acetyltransferase
OM985_20965	COG3290	protein histidine kinase activity
OM985_20965	COG3829	transcription factor binding
OM985_20975	COG0584	glycerophosphoryl diester phosphodiesterase
OM985_20980	COG3093	addiction module antidote protein HigA
OM985_20990	COG0750	zinc metalloprotease
OM985_20995	COG0497	DNA recombination
OM985_21005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OM985_21015	COG0142	geranyltranstransferase activity
OM985_21040	COG1302	Protein conserved in bacteria
OM985_21045	COG0439	Biotin carboxylase
OM985_21050	COG0511	ligase activity, forming carbon-carbon bonds
OM985_21095	COG3854	ATPases associated with a variety of cellular activities
OM985_21120	COG0006	proline dipeptidase activity
OM985_21135	COG3872	metal-dependent enzyme
OM985_21145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM985_21165	COG0095	Lipoate-protein ligase
OM985_21170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM985_21175	COG1609	Transcriptional regulator
OM985_21185	COG2076	Multidrug Resistance protein
OM985_21190	COG2076	Multidrug Resistance protein
OM985_21225	COG1131	(ABC) transporter
OM985_21230	COG1725	Transcriptional regulator
OM985_21260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM985_21320	COG4970	Tfp pilus assembly protein FimT
OM985_21330	COG1459	type II secretion system
OM985_21335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM985_21385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM985_21390	COG0646	methionine synthase
OM985_21390	COG1410	methionine synthase
OM985_21395	COG0646	methionine synthase
OM985_21395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM985_21400	COG0626	cystathionine gamma-synthase activity
OM985_21405	COG0626	cystathionine gamma-synthase activity
OM985_21425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_21435	COG1940	carbohydrate kinase activity
OM985_21440	COG4483	Protein conserved in bacteria
OM985_21445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM985_21450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OM985_21455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM985_21460	COG0704	Plays a role in the regulation of phosphate uptake
OM985_21470	COG0581	inorganic phosphate transmembrane transporter activity
OM985_21475	COG0573	inorganic phosphate transmembrane transporter activity
OM985_21480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM985_21485	COG0768	penicillin binding
OM985_21490	COG0477	Major facilitator Superfamily
OM985_21495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM985_21520	COG0735	belongs to the Fur family
OM985_21525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OM985_21530	COG1121	(ABC) transporter
OM985_21535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_21565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OM985_21570	COG2384	SAM-dependent methyltransferase
OM985_21575	COG2010	Cytochrome c
OM985_21580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM985_21585	COG0358	DNA primase activity
OM985_21595	COG0517	IMP dehydrogenase activity
OM985_21610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM985_21615	COG0295	cytidine deaminase activity
OM985_21620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM985_21630	COG1480	7TM receptor with intracellular HD hydrolase
OM985_21635	COG1702	phosphate starvation-inducible protein PhoH
OM985_21650	COG1610	YqeY-like protein
OM985_21655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OM985_21660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM985_21665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM985_21695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM985_21700	COG1733	regulation of RNA biosynthetic process
OM985_21725	COG1466	dna polymerase III delta subunit
OM985_21735	COG2333	competence protein COMEC
OM985_21735	COG0658	competence protein
OM985_21740	COG2131	deaminase
OM985_21745	COG1596	polysaccharide export
OM985_21745	COG1555	photosystem II stabilization
OM985_21750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM985_21755	COG2226	methyltransferase
OM985_21760	COG0799	negative regulation of ribosome biogenesis
OM985_21765	COG1713	HD superfamily hydrolase involved in NAD metabolism
OM985_21775	COG1534	Rna-binding protein
OM985_21785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OM985_21790	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OM985_21815	COG1595	DNA-templated transcription, initiation
OM985_21825	COG0778	Nitroreductase
OM985_21830	COG2357	RelA SpoT domain protein
OM985_21840	COG1785	Belongs to the alkaline phosphatase family
OM985_21850	COG2267	carboxylic ester hydrolase activity
OM985_21885	COG1404	Belongs to the peptidase S8 family
OM985_21890	COG3186	Phenylalanine-4-hydroxylase
OM985_21905	COG2259	Doxx family
OM985_21945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_21955	COG1454	alcohol dehydrogenase
OM985_21955	COG1012	belongs to the aldehyde dehydrogenase family
OM985_21960	COG0626	cystathionine gamma-synthase activity
OM985_21965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM985_21990	COG0768	penicillin binding
OM985_22005	COG0826	peptidase U32
OM985_22010	COG0826	peptidase U32
OM985_22015	COG4122	O-methyltransferase activity
OM985_22020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM985_22040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OM985_22050	COG0628	permease
OM985_22070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM985_22080	COG0482	sulfurtransferase activity
OM985_22085	COG1104	cysteine desulfurase activity
OM985_22090	COG1959	2 iron, 2 sulfur cluster binding
OM985_22095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM985_22105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM985_22130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM985_22140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM985_22140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OM985_22145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM985_22150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM985_22150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM985_22160	COG2244	polysaccharide biosynthetic process
OM985_22165	COG2323	membrane
OM985_22175	COG1862	Preprotein translocase
OM985_22205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OM985_22215	COG0697	spore germination
OM985_22220	COG0697	spore germination
OM985_22225	COG0640	Transcriptional regulator
OM985_22250	COG0157	Belongs to the NadC ModD family
OM985_22255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OM985_22260	COG1104	cysteine desulfurase activity
OM985_22265	COG1827	regulation of RNA biosynthetic process
OM985_22270	COG2258	MOSC domain
OM985_22275	COG0077	Prephenate dehydratase
OM985_22280	COG0577	efflux transmembrane transporter activity
OM985_22285	COG0577	efflux transmembrane transporter activity
OM985_22290	COG1136	(ABC) transporter
OM985_22300	COG0745	RESPONSE REGULATOR receiver
OM985_22305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OM985_22310	COG3290	protein histidine kinase activity
OM985_22320	COG2868	ribosomal protein
OM985_22330	COG1530	ribonuclease E activity
OM985_22335	COG1994	Peptidase M50
OM985_22340	COG0739	heme binding
OM985_22345	COG2894	cell division
OM985_22365	COG1077	Cell shape determining protein MreB Mrl
OM985_22385	COG0285	dihydrofolate synthase activity
OM985_22390	COG0525	valine-tRNA ligase activity
OM985_22400	COG1388	LysM domain
OM985_22410	COG0113	porphobilinogen synthase activity
OM985_22415	COG1587	Uroporphyrinogen-III synthase
OM985_22425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM985_22435	COG1846	Transcriptional regulator
OM985_22440	COG1764	response to oxidative stress
OM985_22455	COG1067	ATP-dependent peptidase activity
OM985_22455	COG0470	DNA polymerase III
OM985_22500	COG0622	Phosphoesterase
OM985_22515	COG5401	PFAM Sporulation and spore germination
OM985_22535	COG1309	transcriptional regulator
OM985_22550	COG2197	response regulator
OM985_22555	COG2233	PERMEase
OM985_22565	COG0402	S-adenosylhomocysteine deaminase activity
OM985_22570	COG0402	S-adenosylhomocysteine deaminase activity
OM985_22580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM985_22590	COG0444	Belongs to the ABC transporter superfamily
OM985_22595	COG4608	Belongs to the ABC transporter superfamily
OM985_22600	COG3275	phosphorelay sensor kinase activity
OM985_22605	COG3279	Response regulator of the LytR AlgR family
OM985_22620	COG1983	PspC domain protein
OM985_22625	COG1396	sequence-specific DNA binding
OM985_22630	COG0697	spore germination
OM985_22640	COG1959	2 iron, 2 sulfur cluster binding
OM985_22645	COG1668	transmembrane transport
OM985_22650	COG4152	abc transporter atp-binding protein
OM985_22655	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OM985_22665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM985_22670	COG1876	peptidase activity
OM985_22675	COG0824	Thioesterase
OM985_22680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM985_22685	COG1053	succinate dehydrogenase
OM985_22690	COG2009	succinate dehydrogenase
OM985_22695	COG1719	4-vinyl reductase, 4VR
OM985_22705	COG3118	belongs to the thioredoxin family
OM985_22710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OM985_22715	COG2086	electron transfer activity
OM985_22720	COG1024	Enoyl-CoA hydratase
OM985_22730	COG0318	PFAM AMP-dependent synthetase and ligase
OM985_22750	COG2318	DinB family
OM985_22780	COG1131	(ABC) transporter
OM985_22785	COG2205	protein histidine kinase activity
OM985_22790	COG0745	RESPONSE REGULATOR receiver
OM985_22800	COG4895	conserved protein (DUF2196)
OM985_22805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM985_22820	COG4509	Sortase family
OM985_22825	COG1120	ATPase activity
OM985_22840	COG5386	Cell surface protein
OM985_22850	COG5386	Cell surface protein
OM985_22855	COG1114	Component of the transport system for branched-chain amino acids
OM985_22860	COG1187	pseudouridine synthase activity
OM985_22870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OM985_22870	COG1796	DNA polymerase
OM985_22875	COG1286	toxin biosynthetic process
OM985_22920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM985_22930	COG1418	mRNA catabolic process
OM985_22955	COG2814	Major facilitator Superfamily
OM985_22960	COG1566	PFAM secretion protein HlyD family protein
OM985_22965	COG1309	transcriptional regulator
OM985_22970	COG1363	Peptidase, m42
OM985_22995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM985_23005	COG1484	DNA-dependent DNA replication
OM985_23010	COG3611	Membrane attachment protein
OM985_23020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM985_23025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM985_23030	COG0237	dephospho-CoA kinase activity
OM985_23035	COG1971	Probably functions as a manganese efflux pump
OM985_23045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM985_23045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM985_23050	COG5002	protein histidine kinase activity
OM985_23055	COG0745	RESPONSE REGULATOR receiver
OM985_23080	COG0538	isocitrate dehydrogenase activity
OM985_23085	COG0372	Belongs to the citrate synthase family
OM985_23095	COG0628	permease
OM985_23100	COG3030	protein affecting phage T7 exclusion by the F plasmid
OM985_23125	COG1725	Transcriptional regulator
OM985_23130	COG0281	malic enzyme
OM985_23135	COG0587	DNA-directed DNA polymerase activity
OM985_23150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OM985_23170	COG4109	DRTGG domain
OM985_23185	COG0006	proline dipeptidase activity
OM985_23225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_23230	COG0662	Cupin 2, conserved barrel domain protein
OM985_23240	COG1476	TRANSCRIPTIONal
OM985_23255	COG1028	Short-chain dehydrogenase reductase Sdr
OM985_23260	COG0589	response to stress
OM985_23300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_23320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OM985_23325	COG0827	DNA restriction-modification system
OM985_23330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OM985_23335	COG3874	Sporulation protein YtfJ
OM985_23350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OM985_23360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM985_23375	COG1104	cysteine desulfurase activity
OM985_23385	COG0583	DNA-binding transcription factor activity
OM985_23390	COG0697	spore germination
OM985_23400	COG1956	GAF domain-containing protein
OM985_23405	COG0626	cystathionine gamma-synthase activity
OM985_23435	COG1595	DNA-templated transcription, initiation
OM985_23445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM985_23450	COG0454	-acetyltransferase
OM985_23455	COG0517	IMP dehydrogenase activity
OM985_23460	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM985_23470	COG0745	RESPONSE REGULATOR receiver
OM985_23480	COG0666	response to abiotic stimulus
OM985_23515	COG1609	Transcriptional regulator
OM985_23520	COG4851	CamS sex pheromone cAM373 precursor
OM985_23525	COG3118	belongs to the thioredoxin family
OM985_23535	COG2309	aminopeptidase activity
OM985_23555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_23570	COG1674	ftsk spoiiie
OM985_23580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM985_23585	COG4848	Belongs to the UPF0354 family
OM985_23590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM985_23595	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OM985_23600	COG1363	Peptidase, m42
OM985_23610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_23625	COG0510	thiamine kinase activity
OM985_23630	COG1523	belongs to the glycosyl hydrolase 13 family
OM985_23645	COG1349	DNA-binding transcription factor activity
OM985_23650	COG1187	pseudouridine synthase activity
OM985_23655	COG2244	polysaccharide biosynthetic process
OM985_23660	COG2081	HI0933 family
OM985_23665	COG2814	Major facilitator Superfamily
OM985_23675	COG3832	glyoxalase III activity
OM985_23695	COG1329	Transcriptional regulator
OM985_23705	COG4975	Glucose uptake
OM985_23720	COG0314	molybdopterin synthase activity
OM985_23725	COG1763	Mo-molybdopterin cofactor biosynthetic process
OM985_23730	COG0303	'Molybdopterin
OM985_23740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM985_23765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM985_23775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OM985_23820	COG2814	Major facilitator Superfamily
OM985_23825	COG0475	glutathione-regulated potassium exporter activity
OM985_23830	COG0490	domain, Protein
OM985_23835	COG0582	viral genome integration into host DNA
OM985_23845	COG1136	(ABC) transporter
OM985_23865	COG1242	4 iron, 4 sulfur cluster binding
OM985_23870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OM985_23875	COG1131	(ABC) transporter
OM985_23885	COG1794	racemase activity, acting on amino acids and derivatives
OM985_23905	COG2267	carboxylic ester hydrolase activity
OM985_23910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM985_23915	COG0671	phosphoesterase, PA-phosphatase related
OM985_23920	COG0438	transferase activity, transferring glycosyl groups
OM985_23930	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM985_23985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OM985_23990	COG5002	protein histidine kinase activity
OM985_23995	COG4191	Histidine kinase
OM985_24000	COG2267	carboxylic ester hydrolase activity
OM985_24020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM985_24025	COG1116	anion transmembrane transporter activity
OM985_24030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM985_24055	COG0494	nUDIX hydrolase
OM985_24090	COG0288	reversible hydration of carbon dioxide
OM985_24095	COG1271	oxidase subunit
OM985_24100	COG1294	oxidase, subunit
OM985_24120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_24145	COG1842	Phage shock protein A
OM985_24175	COG5002	protein histidine kinase activity
OM985_24180	COG0745	RESPONSE REGULATOR receiver
OM985_24210	COG1597	lipid kinase activity
OM985_24245	COG0586	Pfam SNARE associated Golgi protein
OM985_24255	COG0577	efflux transmembrane transporter activity
OM985_24260	COG1136	(ABC) transporter
OM985_24265	COG3708	Transcriptional regulator
OM985_24265	COG2207	Transcriptional regulator
OM985_24270	COG0745	RESPONSE REGULATOR receiver
OM985_24275	COG2205	protein histidine kinase activity
OM985_24285	COG0577	efflux transmembrane transporter activity
OM985_24290	COG1136	(ABC) transporter
OM985_24310	COG2188	Transcriptional regulator
OM985_24330	COG3964	amidohydrolase
OM985_24360	COG4948	Mandelate Racemase Muconate Lactonizing
OM985_24370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OM985_24375	COG0596	Alpha beta hydrolase
OM985_24380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OM985_24385	COG1169	isochorismate synthase
OM985_24390	COG1575	Belongs to the MenA family. Type 1 subfamily
OM985_24395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM985_24420	COG0058	SHG alpha-glucan phosphorylase activity
OM985_24425	COG0297	glycogen (starch) synthase activity
OM985_24430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OM985_24580	COG1285	pathogenesis
OM985_24585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM985_24595	COG0166	Belongs to the GPI family
OM985_24600	COG2155	Conserved Protein
OM985_24605	COG1098	S1 RNA binding domain
OM985_24610	COG0436	Aminotransferase
OM985_24615	COG1522	sequence-specific DNA binding
OM985_24620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM985_24625	COG2267	carboxylic ester hydrolase activity
OM985_24635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OM985_24655	COG5018	Exonuclease
OM985_24660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OM985_24680	COG2050	protein possibly involved in aromatic compounds catabolism
OM985_24690	COG1268	BioY protein
OM985_24700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM985_24705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM985_24720	COG3584	3D domain protein
OM985_24735	COG1252	NADH dehydrogenase
OM985_24750	COG3708	Transcriptional regulator
OM985_24765	COG1683	Conserved Protein
OM985_24785	COG0316	Belongs to the HesB IscA family
OM985_24800	COG1252	NADH dehydrogenase
OM985_24815	COG0390	transport system, permease component
OM985_24820	COG2824	Alkylphosphonate utilization operon protein PhnA
OM985_24860	COG4837	Protein of unknown function (DUF1462)
OM985_24865	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OM985_24875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM985_24880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OM985_24890	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM985_24895	COG0647	UMP catabolic process
OM985_24905	COG2445	Protein of unknown function DUF86
OM985_24910	COG1494	fructose-1,6-bisphosphatase
OM985_24925	COG4470	Protein conserved in bacteria
OM985_24935	COG0789	Transcriptional regulator
OM985_24940	COG4377	Putative membrane peptidase family (DUF2324)
OM985_24965	COG0739	heme binding
OM985_24975	COG3377	Domain of unknown function (DUF1805)
OM985_24980	COG0737	Belongs to the 5'-nucleotidase family
OM985_24985	COG1695	Transcriptional regulator
OM985_24995	COG0719	Fe-S assembly protein
OM985_25000	COG0822	iron-sulfur transferase activity
OM985_25005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM985_25010	COG0719	Fe-S assembly protein
OM985_25015	COG0396	ATPase activity
OM985_25020	COG1464	Belongs to the NlpA lipoprotein family
OM985_25025	COG1464	Belongs to the NlpA lipoprotein family
OM985_25030	COG2011	ABC-type metal ion transport system permease component
OM985_25035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM985_25045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM985_25050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OM985_25060	COG1393	Belongs to the ArsC family
OM985_25105	COG0039	L-malate dehydrogenase activity
OM985_25130	COG1309	transcriptional regulator
OM985_25135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM985_25140	COG1960	acyl-CoA dehydrogenase activity
OM985_25145	COG0183	Belongs to the thiolase family
OM985_25150	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM985_25150	COG1024	Enoyl-CoA hydratase
OM985_25160	COG1686	Belongs to the peptidase S11 family
OM985_25175	COG0011	TIGRFAM Protein of
OM985_25180	COG0840	transmembrane signaling receptor activity
OM985_25200	COG2814	Major facilitator Superfamily
OM985_25205	COG0531	amino acid
OM985_25215	COG0706	membrane insertase activity
OM985_25225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM985_25260	COG0586	Pfam SNARE associated Golgi protein
OM985_25270	COG1376	ErfK ybiS ycfS ynhG family protein
OM985_25275	COG0745	RESPONSE REGULATOR receiver
OM985_25280	COG5002	protein histidine kinase activity
OM985_25305	COG2151	metal-sulfur cluster biosynthetic enzyme
OM985_25310	COG3227	Zinc metalloprotease (Elastase)
OM985_25315	COG1741	Belongs to the pirin family
OM985_25330	COG0475	glutathione-regulated potassium exporter activity
OM985_25335	COG0490	domain, Protein
OM985_25340	COG1115	amino acid carrier protein
OM985_25345	COG0783	Belongs to the Dps family
OM985_25360	COG1611	Belongs to the LOG family
OM985_25380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_25385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_25390	COG1115	amino acid carrier protein
OM985_25395	COG1115	amino acid carrier protein
OM985_25400	COG2910	NAD(P)H-binding
OM985_25415	COG0656	L-ascorbic acid biosynthetic process
OM985_25420	COG2814	Major facilitator Superfamily
OM985_25425	COG1733	regulation of RNA biosynthetic process
OM985_25435	COG1252	NADH dehydrogenase
OM985_25440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OM985_25445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OM985_25455	COG0840	transmembrane signaling receptor activity
OM985_25455	COG3290	protein histidine kinase activity
OM985_25465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM985_25470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM985_25485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM985_25540	COG0557	exoribonuclease II activity
OM985_25545	COG1647	Serine aminopeptidase, S33
OM985_25550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OM985_25555	COG1346	cytolysis
OM985_25660	COG4695	Portal protein
OM985_25685	COG4974	Belongs to the 'phage' integrase family
OM985_25695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OM985_25700	COG0149	triose-phosphate isomerase activity
OM985_25710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM985_25725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OM985_25750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM985_25765	COG2323	membrane
OM985_25770	COG0740	serine-type endopeptidase activity
OM985_25775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM985_25785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OM985_25795	COG1051	belongs to the nudix hydrolase family
OM985_25805	COG0492	ferredoxin-NADP+ reductase activity
OM985_25810	COG0457	Tetratricopeptide repeat
OM985_25815	COG0110	maltose O-acetyltransferase activity
OM985_25835	COG1950	PFAM Membrane protein of
OM985_25845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM985_25850	COG0556	nucleotide-excision repair
OM985_25870	COG0789	Transcriptional regulator
OM985_25895	COG2855	membrane
OM985_25900	COG0583	DNA-binding transcription factor activity
OM985_25910	COG0655	NAD(P)H dehydrogenase (quinone) activity
OM985_25915	COG0488	(ABC) transporter
OM985_25925	COG1132	(ABC) transporter
OM985_25930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM985_25935	COG0793	Belongs to the peptidase S41A family
OM985_25935	COG3409	Peptidoglycan-binding domain 1 protein
OM985_25940	COG2177	Part of the ABC transporter FtsEX involved in
OM985_25945	COG2884	Cell division ATP-binding protein ftsE
OM985_25960	COG0653	protein targeting
OM985_25965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OM985_25970	COG1278	Cold shock
OM985_25975	COG1040	competence protein
OM985_25980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OM985_25985	COG1388	LysM domain
OM985_25985	COG0791	NLP P60 protein
OM985_25990	COG1733	regulation of RNA biosynthetic process
OM985_25995	COG1307	EDD domain protein, DegV family
OM985_26000	COG1739	Uncharacterized protein family UPF0029
OM985_26005	COG1316	TRANSCRIPTIONal
OM985_26010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OM985_26015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OM985_26020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM985_26030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OM985_26030	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OM985_26045	COG3394	polysaccharide catabolic process
OM985_26050	COG1486	melibiose metabolic process
OM985_26055	COG1447	Phosphotransferase system cellobiose-specific component IIA
OM985_26060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM985_26070	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM985_26075	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OM985_26080	COG1447	Phosphotransferase system cellobiose-specific component IIA
OM985_26090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM985_26095	COG1301	dicarboxylic acid transport
OM985_26105	COG0346	lactoylglutathione lyase activity
OM985_26110	COG1511	domain protein
OM985_26115	COG0583	DNA-binding transcription factor activity
OM985_26120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM985_26135	COG1271	oxidase subunit
OM985_26140	COG1294	oxidase, subunit
OM985_26145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OM985_26155	COG1620	l-lactate permease
OM985_26165	COG2389	metal-binding protein
OM985_26175	COG1368	sulfuric ester hydrolase activity
OM985_26190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM985_26210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM985_26215	COG3584	3D domain protein
OM985_26215	COG1388	LysM domain
OM985_26240	COG4715	Zinc finger, swim domain protein
OM985_26245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM985_26285	COG0577	efflux transmembrane transporter activity
OM985_26290	COG1136	(ABC) transporter
OM985_26325	COG5002	protein histidine kinase activity
OM985_26330	COG0745	RESPONSE REGULATOR receiver
OM985_26335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OM985_26355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OM985_26360	COG1134	teichoic acid transport
OM985_26365	COG1682	transport, permease protein
OM985_26370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OM985_26415	COG1609	Transcriptional regulator
OM985_26430	COG0739	heme binding
OM985_26450	COG2385	sporulation resulting in formation of a cellular spore
OM985_26465	COG4836	Membrane
OM985_26470	COG1007	ATP synthesis coupled electron transport
OM985_26475	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM985_26480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM985_26490	COG0839	Belongs to the complex I subunit 6 family
OM985_26505	COG0649	NAD binding
OM985_26510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OM985_26525	COG3300	MHYT domain
OM985_26525	COG5001	Diguanylate cyclase
OM985_26575	COG0356	it plays a direct role in the translocation of protons across the membrane
OM985_26610	COG0698	ribose 5-phosphate isomerase
OM985_26620	COG2190	(PTS) system
OM985_26625	COG2259	Doxx family
OM985_26630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OM985_26645	COG0009	L-threonylcarbamoyladenylate synthase
OM985_26660	COG2890	protein-(glutamine-N5) methyltransferase activity
OM985_26680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM985_26685	COG1494	fructose-1,6-bisphosphatase
OM985_26705	COG4821	SIS domain
OM985_26715	COG3343	RNA polymerase activity
OM985_26725	COG1960	acyl-CoA dehydrogenase activity
OM985_26730	COG1960	acyl-CoA dehydrogenase activity
OM985_26735	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM985_26740	COG0183	Belongs to the thiolase family
OM985_26745	COG0247	lactate metabolic process
OM985_26745	COG2181	nitrate reductase activity
OM985_26750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM985_26760	COG5001	Diguanylate cyclase
OM985_26760	COG3300	MHYT domain
OM985_26780	COG2197	response regulator
OM985_26785	COG4585	Histidine kinase
OM985_26790	COG0842	Transport permease protein
OM985_26795	COG1131	(ABC) transporter
OM985_26800	COG0024	Methionine aminopeptidase
OM985_26815	COG2234	aminopeptidase activity
OM985_26835	COG1595	DNA-templated transcription, initiation
OM985_26840	COG0018	arginyl-trna synthetase
OM985_26845	COG4506	Protein conserved in bacteria
OM985_26850	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM985_26865	COG0010	Belongs to the arginase family
OM985_26875	COG2814	Major facilitator Superfamily
OM985_26880	COG0789	Transcriptional regulator
OM985_26885	COG0584	glycerophosphoryl diester phosphodiesterase
OM985_26890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM985_26900	COG1994	Peptidase M50
OM985_26910	COG1078	dGTPase activity
OM985_26915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM985_26920	COG1120	ATPase activity
OM985_26925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM985_26950	COG0095	Lipoate-protein ligase
OM985_26955	COG0280	phosphate acetyltransferase
OM985_26970	COG3773	Cell wall hydrolase
OM985_26980	COG2363	Small membrane protein
OM985_26995	COG2233	PERMEase
OM985_27000	COG0561	phosphatase activity
OM985_27005	COG2814	Major facilitator Superfamily
OM985_27015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM985_27020	COG1131	(ABC) transporter
OM985_27025	COG2755	lipolytic protein G-D-S-L family
OM985_27030	COG1609	Transcriptional regulator
OM985_27040	COG0460	homoserine dehydrogenase
OM985_27050	COG2873	o-acetylhomoserine
OM985_27060	COG1011	Hydrolase
OM985_27065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM985_27075	COG2197	response regulator
OM985_27085	COG0351	phosphomethylpyrimidine kinase
OM985_27090	COG3706	GGDEF domain
OM985_27095	COG2879	small protein
OM985_27100	COG1966	Carbon starvation protein
OM985_27105	COG3279	Response regulator of the LytR AlgR family
OM985_27110	COG0477	Major facilitator Superfamily
OM985_27135	COG0840	transmembrane signaling receptor activity
OM985_27145	COG1607	acyl-coa hydrolase
OM985_27160	COG0488	(ABC) transporter
OM985_27180	COG0463	Glycosyl transferase, family 2
OM985_27185	COG1309	transcriptional regulator
OM985_27190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM985_27195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM985_27195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OM985_27200	COG0628	permease
OM985_27215	COG3279	Response regulator of the LytR AlgR family
OM985_27220	COG3275	phosphorelay sensor kinase activity
OM985_27225	COG2814	Major facilitator Superfamily
OM985_27230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM985_27235	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OM985_27240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM985_27260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OM985_27265	COG1272	protein, Hemolysin III
OM985_27285	COG0516	GMP reductase activity
OM985_27290	COG1164	Oligoendopeptidase f
OM985_27310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM985_27315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM985_27320	COG4853	Protein conserved in bacteria
OM985_27325	COG4863	YycH protein
OM985_27330	COG5002	protein histidine kinase activity
OM985_27335	COG0745	RESPONSE REGULATOR receiver
OM985_27365	COG0305	Participates in initiation and elongation during chromosome replication
OM985_27375	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OM985_27380	COG4241	membrane
OM985_27390	COG0629	single-stranded DNA binding
OM985_27400	COG0012	GTP binding
OM985_27405	COG4481	Protein conserved in bacteria
OM985_27410	COG0668	transmembrane transport
OM985_27420	COG1475	DNA binding
OM985_27425	COG1192	Involved in chromosome partitioning
OM985_27450	COG1847	R3H domain protein
OM985_27455	COG0706	membrane insertase activity
OM985_27465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OM985_27480	COG2311	Membrane
OM985_27615	COG4962	Type ii secretion system protein e
OM985_27820	COG3344	reverse transcriptase
OM985_27900	COG3344	reverse transcriptase
OM985_28005	COG0457	Tetratricopeptide repeat
OM985_28030	COG4974	Belongs to the 'phage' integrase family
OM985_28040	COG3443	Belongs to the bacterial solute-binding protein 9 family
OM985_28105	COG4974	Belongs to the 'phage' integrase family
OM985_28115	COG2002	toxin-antitoxin pair type II binding
OM985_28295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OM985_28300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM985_28320	COG0671	phosphoesterase, PA-phosphatase related
OM985_28325	COG4196	transglutaminase domain protein