locus-tag	class	description
KM403_00010	COG0592	DNA-directed DNA polymerase activity
KM403_00015	COG2501	S4 domain
KM403_00025	COG0187	DNA topoisomerase II activity
KM403_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM403_00065	COG0516	GMP reductase activity
KM403_00065	COG0517	IMP dehydrogenase activity
KM403_00070	COG1686	Belongs to the peptidase S11 family
KM403_00100	COG1428	Deoxynucleoside kinase
KM403_00105	COG1428	Deoxynucleoside kinase
KM403_00110	COG1335	isochorismatase
KM403_00115	COG0590	tRNA wobble adenosine to inosine editing
KM403_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM403_00180	COG1982	Orn Lys Arg decarboxylase major
KM403_00190	COG0470	DNA polymerase III
KM403_00195	COG1774	PSP1 C-terminal conserved region
KM403_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM403_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM403_00220	COG2002	toxin-antitoxin pair type II binding
KM403_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM403_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM403_00230	COG0084	hydrolase, TatD family'
KM403_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM403_00250	COG4466	Protein conserved in bacteria
KM403_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM403_00270	COG0251	oxidation-reduction process
KM403_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM403_00305	COG2002	toxin-antitoxin pair type II binding
KM403_00310	COG2244	polysaccharide biosynthetic process
KM403_00315	COG3956	TIGRFAM MazG family protein
KM403_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM403_00340	COG1098	S1 RNA binding domain
KM403_00355	COG2208	phosphoserine phosphatase activity
KM403_00360	COG0037	tRNA processing
KM403_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM403_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM403_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM403_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM403_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM403_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM403_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM403_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM403_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM403_00420	COG1396	sequence-specific DNA binding
KM403_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM403_00455	COG3880	PFAM UvrB UvrC protein
KM403_00465	COG0542	response to heat
KM403_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM403_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM403_00500	COG1045	serine acetyltransferase
KM403_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM403_00520	COG3688	RNA-binding protein containing a PIN domain
KM403_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM403_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM403_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM403_00565	COG2813	Specifically methylates the guanine in position
KM403_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM403_00580	COG1358	cellular component organization or biogenesis
KM403_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM403_00710	COG0201	protein transport
KM403_00720	COG0024	Methionine aminopeptidase
KM403_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM403_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM403_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM403_00795	COG0489	protein tyrosine kinase activity
KM403_00805	COG2194	sulfuric ester hydrolase activity
KM403_00810	COG0726	polysaccharide deacetylase
KM403_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM403_00895	COG4856	YbbR-like protein
KM403_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM403_00915	COG0596	Alpha beta hydrolase
KM403_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM403_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM403_00940	COG4946	Tricorn protease homolog
KM403_00940	COG1506	peptidase
KM403_00975	COG2011	ABC-type metal ion transport system permease component
KM403_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM403_00985	COG1464	Belongs to the NlpA lipoprotein family
KM403_00990	COG0604	alcohol dehydrogenase
KM403_01000	COG0277	FAD linked oxidase domain protein
KM403_01005	COG2271	Major facilitator Superfamily
KM403_01015	COG2814	Major facilitator Superfamily
KM403_01030	COG0601	transmembrane transport
KM403_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM403_01040	COG0444	Belongs to the ABC transporter superfamily
KM403_01045	COG4608	Belongs to the ABC transporter superfamily
KM403_01050	COG4166	transmembrane transport
KM403_01060	COG2207	Transcriptional regulator
KM403_01075	COG4166	transmembrane transport
KM403_01080	COG4166	transmembrane transport
KM403_01085	COG0656	L-ascorbic acid biosynthetic process
KM403_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM403_01105	COG4149	molybdate abc transporter
KM403_01115	COG1910	domain protein
KM403_01125	COG0583	DNA-binding transcription factor activity
KM403_01130	COG0697	spore germination
KM403_01145	COG0204	Acyl-transferase
KM403_01155	COG1609	Transcriptional regulator
KM403_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_01175	COG0084	hydrolase, TatD family'
KM403_01180	COG5298	Protein conserved in bacteria
KM403_01205	COG0488	(ABC) transporter
KM403_01220	COG0747	negative chemotaxis
KM403_01225	COG0601	transmembrane transport
KM403_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM403_01235	COG0444	Belongs to the ABC transporter superfamily
KM403_01240	COG4608	Belongs to the ABC transporter superfamily
KM403_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM403_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM403_01290	COG2814	Major facilitator Superfamily
KM403_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM403_01310	COG4294	response to UV
KM403_01315	COG0705	Rhomboid family
KM403_01315	COG0457	Tetratricopeptide repeat
KM403_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM403_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM403_01335	COG0864	Transcriptional regulator
KM403_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM403_01345	COG2183	response to ionizing radiation
KM403_01440	COG0802	atpase or kinase
KM403_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM403_01450	COG0456	acetyltransferase
KM403_01460	COG0488	(ABC) transporter
KM403_01475	COG1266	CAAX protease self-immunity
KM403_01495	COG2252	PERMEase
KM403_01505	COG5002	protein histidine kinase activity
KM403_01535	COG2226	methyltransferase
KM403_01575	COG1968	undecaprenyl-diphosphatase activity
KM403_01590	COG2205	protein histidine kinase activity
KM403_01595	COG0745	RESPONSE REGULATOR receiver
KM403_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM403_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM403_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM403_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM403_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM403_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM403_01670	COG0151	Belongs to the GarS family
KM403_01695	COG0210	DNA helicase
KM403_01705	COG4851	CamS sex pheromone cAM373 precursor
KM403_01725	COG1335	isochorismatase
KM403_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM403_01735	COG2011	ABC-type metal ion transport system permease component
KM403_01740	COG1464	Belongs to the NlpA lipoprotein family
KM403_01760	COG1846	Transcriptional regulator
KM403_01785	COG1597	lipid kinase activity
KM403_01790	COG0546	phosphoglycolate phosphatase activity
KM403_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM403_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM403_01810	COG2076	Multidrug Resistance protein
KM403_01815	COG2309	aminopeptidase activity
KM403_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM403_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM403_01850	COG4807	Protein conserved in bacteria
KM403_01875	COG1757	Na H antiporter
KM403_01880	COG1473	amidohydrolase
KM403_01895	COG0450	alkyl hydroperoxide reductase
KM403_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_01940	COG0166	Belongs to the GPI family
KM403_01975	COG5002	protein histidine kinase activity
KM403_01995	COG3541	Predicted nucleotidyltransferase
KM403_02000	COG2814	Major facilitator Superfamily
KM403_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM403_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM403_02015	COG0765	amino acid transport
KM403_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM403_02030	COG0840	transmembrane signaling receptor activity
KM403_02035	COG0840	transmembrane signaling receptor activity
KM403_02040	COG0366	Alpha amylase catalytic
KM403_02045	COG2190	(PTS) system
KM403_02045	COG1263	PTS System
KM403_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM403_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM403_02100	COG1116	anion transmembrane transporter activity
KM403_02105	COG0488	(ABC) transporter
KM403_02150	COG2270	Major facilitator Superfamily
KM403_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM403_02180	COG2310	stress, protein
KM403_02185	COG2310	stress, protein
KM403_02190	COG2310	stress, protein
KM403_02195	COG0861	Integral membrane protein TerC family
KM403_02205	COG3853	Toxic anion resistance protein (TelA)
KM403_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM403_02230	COG1295	ribonuclease BN
KM403_02235	COG2217	Heavy metal translocating P-type atpase
KM403_02240	COG0697	spore germination
KM403_02260	COG0586	Pfam SNARE associated Golgi protein
KM403_02275	COG3871	stress protein (general stress protein 26)
KM403_02280	COG0387	Pfam Sodium calcium exchanger
KM403_02290	COG0535	radical SAM domain protein
KM403_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM403_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM403_02325	COG0582	viral genome integration into host DNA
KM403_02335	COG1396	sequence-specific DNA binding
KM403_02350	COG1396	sequence-specific DNA binding
KM403_02385	COG1484	DNA-dependent DNA replication
KM403_02615	COG0101	tRNA pseudouridine synthase activity
KM403_02625	COG3829	transcription factor binding
KM403_02635	COG0833	amino acid
KM403_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM403_02670	COG1263	PTS System
KM403_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM403_02690	COG0463	Glycosyl transferase, family 2
KM403_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM403_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM403_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM403_02745	COG1228	amidohydrolase
KM403_02750	COG1090	epimerase
KM403_02780	COG1988	membrane-bound metal-dependent
KM403_02785	COG1194	a g-specific adenine glycosylase
KM403_02810	COG1132	(ABC) transporter
KM403_02815	COG4129	membrane
KM403_02820	COG0069	glutamate synthase activity
KM403_02820	COG0067	glutamate synthase
KM403_02820	COG0070	glutamate synthase
KM403_02830	COG4555	ABC transporter
KM403_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM403_02855	COG0735	belongs to the Fur family
KM403_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM403_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM403_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM403_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM403_03005	COG2766	serine protein kinase
KM403_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM403_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM403_03040	COG2268	Band 7 protein
KM403_03050	COG3290	protein histidine kinase activity
KM403_03055	COG4565	transcriptional regulatory protein
KM403_03060	COG2851	Citrate transporter
KM403_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM403_03085	COG3842	ATPase activity
KM403_03090	COG1175	transmembrane transport
KM403_03095	COG0395	ABC-type sugar transport system, permease component
KM403_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM403_03110	COG0745	RESPONSE REGULATOR receiver
KM403_03115	COG5002	protein histidine kinase activity
KM403_03125	COG4990	cell redox homeostasis
KM403_03135	COG3290	protein histidine kinase activity
KM403_03140	COG4565	transcriptional regulatory protein
KM403_03145	COG3493	citrate carrier protein
KM403_03150	COG0281	malic enzyme
KM403_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_03175	COG5002	protein histidine kinase activity
KM403_03180	COG0745	RESPONSE REGULATOR receiver
KM403_03185	COG0454	-acetyltransferase
KM403_03185	COG0456	acetyltransferase
KM403_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM403_03195	COG3383	formate dehydrogenase (NAD+) activity
KM403_03200	COG2427	Protein of unknown function (DUF1641)
KM403_03215	COG0531	amino acid
KM403_03220	COG0640	Transcriptional regulator
KM403_03225	COG2217	Heavy metal translocating P-type atpase
KM403_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM403_03245	COG3227	Zinc metalloprotease (Elastase)
KM403_03265	COG2720	vancomycin resistance protein
KM403_03270	COG1316	TRANSCRIPTIONal
KM403_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_03280	COG0346	lactoylglutathione lyase activity
KM403_03285	COG1253	flavin adenine dinucleotide binding
KM403_03290	COG1027	Aspartate ammonia-lyase
KM403_03295	COG1620	l-lactate permease
KM403_03310	COG3104	oligopeptide transport
KM403_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_03335	COG2226	methyltransferase
KM403_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM403_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM403_03355	COG4548	von Willebrand factor, type A
KM403_03360	COG0714	Associated with various cellular activities
KM403_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM403_03385	COG0531	amino acid
KM403_03390	COG2188	Transcriptional regulator
KM403_03395	COG1263	PTS System
KM403_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_03400	COG0366	Alpha amylase catalytic
KM403_03415	COG0697	spore germination
KM403_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM403_03430	COG1115	amino acid carrier protein
KM403_03435	COG1126	abc transporter atp-binding protein
KM403_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM403_03445	COG0765	amino acid transport
KM403_03450	COG0765	amino acid transport
KM403_03455	COG0833	amino acid
KM403_03480	COG2378	regulation of single-species biofilm formation
KM403_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM403_03490	COG5002	protein histidine kinase activity
KM403_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM403_03520	COG0747	negative chemotaxis
KM403_03530	COG0601	transmembrane transport
KM403_03535	COG4608	Belongs to the ABC transporter superfamily
KM403_03545	COG2271	Major facilitator Superfamily
KM403_03550	COG1846	Transcriptional regulator
KM403_03560	COG1609	Transcriptional regulator
KM403_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM403_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM403_03585	COG1879	ABC-type sugar transport system periplasmic component
KM403_03610	COG1063	alcohol dehydrogenase
KM403_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM403_03650	COG1968	undecaprenyl-diphosphatase activity
KM403_03655	COG0840	transmembrane signaling receptor activity
KM403_03660	COG3584	3D domain protein
KM403_03660	COG1388	LysM domain
KM403_03665	COG1476	TRANSCRIPTIONal
KM403_03680	COG3104	oligopeptide transport
KM403_03685	COG1114	Component of the transport system for branched-chain amino acids
KM403_03700	COG1113	amino acid transport
KM403_03705	COG2252	PERMEase
KM403_03730	COG0569	domain protein
KM403_03730	COG0475	glutathione-regulated potassium exporter activity
KM403_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM403_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM403_03755	COG0833	amino acid
KM403_03760	COG4990	cell redox homeostasis
KM403_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM403_03780	COG0697	spore germination
KM403_03785	COG0531	amino acid
KM403_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM403_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM403_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM403_03805	COG1918	ferrous iron import across plasma membrane
KM403_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM403_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM403_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM403_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM403_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM403_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM403_03975	COG1116	anion transmembrane transporter activity
KM403_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM403_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM403_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM403_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM403_04000	COG2104	thiamine diphosphate biosynthetic process
KM403_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM403_04015	COG0351	phosphomethylpyrimidine kinase
KM403_04055	COG2205	protein histidine kinase activity
KM403_04060	COG2814	Major facilitator Superfamily
KM403_04065	COG1846	Transcriptional regulator
KM403_04080	COG2252	PERMEase
KM403_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM403_04105	COG1621	beta-fructofuranosidase activity
KM403_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_04110	COG1263	PTS System
KM403_04115	COG1609	Transcriptional regulator
KM403_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM403_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM403_04165	COG0778	Nitroreductase
KM403_04170	COG2719	SpoVR family
KM403_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM403_04200	COG1937	Protein conserved in bacteria
KM403_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM403_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM403_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM403_04235	COG0730	response to heat
KM403_04245	COG1316	TRANSCRIPTIONal
KM403_04250	COG0604	alcohol dehydrogenase
KM403_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM403_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM403_04270	COG3711	transcriptional antiterminator
KM403_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM403_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM403_04300	COG1388	LysM domain
KM403_04300	COG3584	3D domain protein
KM403_04305	COG0577	efflux transmembrane transporter activity
KM403_04310	COG1136	(ABC) transporter
KM403_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM403_04335	COG1114	Component of the transport system for branched-chain amino acids
KM403_04340	COG3546	catalase activity
KM403_04375	COG0586	Pfam SNARE associated Golgi protein
KM403_04410	COG0531	amino acid
KM403_04415	COG0475	glutathione-regulated potassium exporter activity
KM403_04425	COG1737	Transcriptional regulator
KM403_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_04435	COG1263	PTS System
KM403_04445	COG2259	Doxx family
KM403_04460	COG0697	spore germination
KM403_04465	COG1522	sequence-specific DNA binding
KM403_04480	COG2076	Multidrug Resistance protein
KM403_04485	COG1309	transcriptional regulator
KM403_04490	COG2814	Major facilitator Superfamily
KM403_04495	COG1733	regulation of RNA biosynthetic process
KM403_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM403_04510	COG4533	DNA binding
KM403_04515	COG2211	Major facilitator Superfamily
KM403_04525	COG0693	protein deglycase activity
KM403_04530	COG0753	catalase activity
KM403_04530	COG0693	protein deglycase activity
KM403_04540	COG0531	amino acid
KM403_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM403_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM403_04560	COG1132	(ABC) transporter
KM403_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM403_04575	COG0765	amino acid transport
KM403_04580	COG1126	abc transporter atp-binding protein
KM403_04595	COG0189	ligase activity
KM403_04625	COG0028	Belongs to the TPP enzyme family
KM403_04630	COG3527	Alpha-acetolactate decarboxylase
KM403_04645	COG0561	phosphatase activity
KM403_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM403_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM403_04695	COG0653	protein targeting
KM403_04700	COG2244	polysaccharide biosynthetic process
KM403_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM403_04715	COG4196	transglutaminase domain protein
KM403_04730	COG1696	Membrane protein involved in D-alanine export
KM403_04745	COG1024	Enoyl-CoA hydratase
KM403_04765	COG1363	Peptidase, m42
KM403_04785	COG3938	Belongs to the proline racemase family
KM403_04825	COG0601	transmembrane transport
KM403_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM403_04840	COG4608	Belongs to the ABC transporter superfamily
KM403_04845	COG0322	excinuclease ABC activity
KM403_04875	COG0477	Major facilitator Superfamily
KM403_04880	COG3290	protein histidine kinase activity
KM403_04885	COG4565	transcriptional regulatory protein
KM403_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM403_04920	COG0789	Transcriptional regulator
KM403_04920	COG4978	Transcriptional regulator
KM403_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM403_04975	COG0477	Major facilitator Superfamily
KM403_05020	COG3320	Male sterility
KM403_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM403_05025	COG1309	transcriptional regulator
KM403_05045	COG1183	phosphatidylcholine synthase activity
KM403_05065	COG2376	Dihydroxyacetone kinase
KM403_05075	COG2376	Dihydroxyacetone kinase
KM403_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM403_05085	COG1959	2 iron, 2 sulfur cluster binding
KM403_05115	COG2770	Histidine kinase
KM403_05115	COG3437	response regulator, receiver
KM403_05165	COG3237	CsbD-like
KM403_05190	COG1191	sigma factor activity
KM403_05200	COG2208	phosphoserine phosphatase activity
KM403_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM403_05210	COG2205	protein histidine kinase activity
KM403_05210	COG2198	Histidine kinase
KM403_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM403_05210	COG0784	Response regulator, receiver
KM403_05265	COG0420	3'-5' exonuclease activity
KM403_05270	COG4717	serine-type aminopeptidase activity
KM403_05290	COG1309	transcriptional regulator
KM403_05295	COG2814	Major facilitator Superfamily
KM403_05300	COG0346	lactoylglutathione lyase activity
KM403_05310	COG0346	lactoylglutathione lyase activity
KM403_05315	COG0457	Tetratricopeptide repeat
KM403_05320	COG2267	carboxylic ester hydrolase activity
KM403_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM403_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM403_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM403_05395	COG0477	Major facilitator Superfamily
KM403_05400	COG0477	Major facilitator Superfamily
KM403_05410	COG3973	AAA domain
KM403_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM403_05435	COG4980	gas vesicle protein
KM403_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM403_05445	COG1131	(ABC) transporter
KM403_05450	COG4473	ABC transporter
KM403_05465	COG1309	transcriptional regulator
KM403_05475	COG3402	PFAM membrane-flanked domain
KM403_05525	COG3402	PFAM membrane-flanked domain
KM403_05530	COG3428	Bacterial PH domain
KM403_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM403_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM403_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM403_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM403_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM403_05590	COG1309	transcriptional regulator
KM403_05595	COG1511	domain protein
KM403_05620	COG1609	Transcriptional regulator
KM403_05630	COG1234	tRNA 3'-trailer cleavage
KM403_05635	COG0095	Lipoate-protein ligase
KM403_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_05675	COG3209	COG3209 Rhs family protein
KM403_05715	COG1078	dGTPase activity
KM403_05725	COG1595	DNA-templated transcription, initiation
KM403_05730	COG2207	Transcriptional regulator
KM403_05730	COG3708	Transcriptional regulator
KM403_05745	COG2205	protein histidine kinase activity
KM403_05750	COG0745	RESPONSE REGULATOR receiver
KM403_05780	COG0501	Belongs to the peptidase M48B family
KM403_05785	COG0840	transmembrane signaling receptor activity
KM403_05790	COG0697	spore germination
KM403_05810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM403_05815	COG2224	Isocitrate lyase
KM403_05840	COG4903	ComK protein
KM403_05845	COG0398	Pfam SNARE associated Golgi protein
KM403_05855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM403_05860	COG1074	ATP-dependent DNA helicase activity
KM403_05905	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM403_05930	COG0367	asparagine synthase
KM403_05935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM403_05940	COG0753	catalase activity
KM403_05945	COG0004	ammonium transporteR
KM403_05965	COG2996	Protein conserved in bacteria
KM403_05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM403_05985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_06000	COG0561	phosphatase activity
KM403_06010	COG0542	response to heat
KM403_06020	COG2267	carboxylic ester hydrolase activity
KM403_06035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM403_06045	COG5504	Zn-dependent protease
KM403_06055	COG0180	Tryptophanyl-tRNA synthetase
KM403_06065	COG4166	transmembrane transport
KM403_06070	COG0601	transmembrane transport
KM403_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM403_06080	COG0444	Belongs to the ABC transporter superfamily
KM403_06085	COG4608	Belongs to the ABC transporter superfamily
KM403_06090	COG0534	Mate efflux family protein
KM403_06095	COG4166	transmembrane transport
KM403_06110	COG0861	Integral membrane protein TerC family
KM403_06115	COG4862	establishment of competence for transformation
KM403_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM403_06130	COG1164	Oligoendopeptidase f
KM403_06140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM403_06145	COG2346	COG2346, Truncated hemoglobins
KM403_06150	COG4116	CYTH
KM403_06160	COG2357	RelA SpoT domain protein
KM403_06170	COG0564	pseudouridine synthase activity
KM403_06190	COG0463	Glycosyl transferase, family 2
KM403_06190	COG1216	Glycosyl transferase, family 2
KM403_06210	COG0457	Tetratricopeptide repeat
KM403_06210	COG0463	Glycosyl transferase, family 2
KM403_06230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM403_06245	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM403_06290	COG2153	protein acetylation
KM403_06300	COG2382	esterase
KM403_06315	COG5492	domain, Protein
KM403_06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM403_06330	COG0512	Glutamine amidotransferase of anthranilate synthase
KM403_06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM403_06365	COG1620	l-lactate permease
KM403_06370	COG5634	Uncharacterized conserved protein (DUF2278)
KM403_06425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM403_06435	COG1476	TRANSCRIPTIONal
KM403_06495	COG2226	methyltransferase
KM403_06505	COG1686	Belongs to the peptidase S11 family
KM403_06510	COG0681	Belongs to the peptidase S26 family
KM403_06545	COG1012	belongs to the aldehyde dehydrogenase family
KM403_06550	COG3842	ATPase activity
KM403_06555	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM403_06560	COG1177	transmembrane transport
KM403_06565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM403_06575	COG2409	Drug exporters of the RND superfamily
KM403_06585	COG0564	pseudouridine synthase activity
KM403_06595	COG2340	Cysteine-rich secretory protein family
KM403_06600	COG0247	lactate metabolic process
KM403_06605	COG0277	FAD linked oxidase domain protein
KM403_06610	COG3835	regulator
KM403_06620	COG0745	RESPONSE REGULATOR receiver
KM403_06625	COG5002	protein histidine kinase activity
KM403_06630	COG2186	Transcriptional regulator
KM403_06650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM403_06665	COG2116	formate transmembrane transporter activity
KM403_06670	COG0861	Integral membrane protein TerC family
KM403_06675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM403_06685	COG2030	dehydratase
KM403_06705	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_06710	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM403_06715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM403_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM403_06735	COG1840	ABC-type Fe3 transport system, periplasmic component
KM403_06765	COG1349	DNA-binding transcription factor activity
KM403_06785	COG2861	carbohydrate metabolic process
KM403_06795	COG3852	Histidine kinase
KM403_06800	COG1846	Transcriptional regulator
KM403_06810	COG2318	DinB family
KM403_06815	COG5002	protein histidine kinase activity
KM403_06825	COG0720	synthase
KM403_06840	COG4873	Protein conserved in bacteria
KM403_06870	COG1780	Probably involved in ribonucleotide reductase function
KM403_06890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM403_06895	COG1725	Transcriptional regulator
KM403_06900	COG1131	(ABC) transporter
KM403_06910	COG1131	(ABC) transporter
KM403_06915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM403_06930	COG1522	sequence-specific DNA binding
KM403_06940	COG1335	isochorismatase
KM403_06950	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM403_06955	COG2070	2-Nitropropane dioxygenase
KM403_06960	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM403_06970	COG1696	Membrane protein involved in D-alanine export
KM403_06995	COG0716	FMN binding
KM403_07010	COG3173	Aminoglycoside phosphotransferase
KM403_07030	COG0534	Mate efflux family protein
KM403_07035	COG1968	undecaprenyl-diphosphatase activity
KM403_07050	COG1846	Transcriptional regulator
KM403_07060	COG1301	dicarboxylic acid transport
KM403_07065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM403_07070	COG4709	membrane
KM403_07075	COG3874	Sporulation protein YtfJ
KM403_07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM403_07105	COG0028	Belongs to the TPP enzyme family
KM403_07110	COG0440	acetolactate synthase activity
KM403_07115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM403_07125	COG0473	3-isopropylmalate dehydrogenase activity
KM403_07150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM403_07185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM403_07200	COG1183	phosphatidylcholine synthase activity
KM403_07205	COG1368	sulfuric ester hydrolase activity
KM403_07215	COG0019	diaminopimelate decarboxylase activity
KM403_07235	COG0529	Catalyzes the synthesis of activated sulfate
KM403_07240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM403_07260	COG1648	precorrin-2 dehydrogenase activity
KM403_07265	COG0733	neurotransmitter:sodium symporter activity
KM403_07285	COG1757	Na H antiporter
KM403_07300	COG4758	membrane
KM403_07305	COG4585	Histidine kinase
KM403_07310	COG2197	response regulator
KM403_07320	COG1114	Component of the transport system for branched-chain amino acids
KM403_07330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM403_07355	COG1017	nitric oxide dioxygenase activity
KM403_07355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM403_07370	COG0730	response to heat
KM403_07375	COG0306	phosphate transporter
KM403_07380	COG1392	Phosphate transport regulator
KM403_07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM403_07400	COG3852	Histidine kinase
KM403_07405	COG1801	Protein of unknown function DUF72
KM403_07415	COG0582	viral genome integration into host DNA
KM403_07420	COG5002	protein histidine kinase activity
KM403_07440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM403_07440	COG0392	lysyltransferase activity
KM403_07455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM403_07460	COG1686	Belongs to the peptidase S11 family
KM403_07465	COG2715	membrane protein required for spore maturation
KM403_07470	COG0700	Nucleoside recognition
KM403_07475	COG1187	pseudouridine synthase activity
KM403_07485	COG1333	cytochrome c biogenesis protein
KM403_07490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM403_07495	COG0745	RESPONSE REGULATOR receiver
KM403_07500	COG5002	protein histidine kinase activity
KM403_07505	COG2096	Adenosyltransferase
KM403_07520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM403_07525	COG1141	Ferredoxin
KM403_07530	COG4955	Helix-turn-helix domain
KM403_07535	COG0514	ATP-dependent DNA helicase (RecQ)
KM403_07540	COG1266	CAAX protease self-immunity
KM403_07560	COG4862	establishment of competence for transformation
KM403_07565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM403_07585	COG0492	ferredoxin-NADP+ reductase activity
KM403_07660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM403_07675	COG0142	geranyltranstransferase activity
KM403_07685	COG0142	geranyltranstransferase activity
KM403_07705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM403_07710	COG0457	Tetratricopeptide repeat
KM403_07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM403_07740	COG4347	Protein of unknown function (DUF1405)
KM403_07755	COG2738	Putative neutral zinc metallopeptidase
KM403_07765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_07770	COG1694	Mazg nucleotide pyrophosphohydrolase
KM403_07785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM403_07790	COG0438	transferase activity, transferring glycosyl groups
KM403_07845	COG3935	DnaD domain protein
KM403_07850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM403_07860	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM403_07860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM403_07925	COG0116	Belongs to the methyltransferase superfamily
KM403_07935	COG1199	ATP-dependent helicase activity
KM403_07940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM403_07950	COG3173	Aminoglycoside phosphotransferase
KM403_07955	COG0024	Methionine aminopeptidase
KM403_07965	COG2233	PERMEase
KM403_07970	COG2311	Membrane
KM403_07975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM403_07985	COG0456	acetyltransferase
KM403_08035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM403_08060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM403_08075	COG1215	transferase activity, transferring glycosyl groups
KM403_08080	COG0438	transferase activity, transferring glycosyl groups
KM403_08095	COG0454	-acetyltransferase
KM403_08115	COG0328	RNA-DNA hybrid ribonuclease activity
KM403_08155	COG1280	lysine exporter protein (LysE YggA)
KM403_08170	COG3162	membrane
KM403_08175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM403_08180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM403_08190	COG0475	glutathione-regulated potassium exporter activity
KM403_08195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM403_08200	COG0789	Transcriptional regulator
KM403_08200	COG4978	Transcriptional regulator
KM403_08210	COG2323	membrane
KM403_08215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM403_08270	COG1923	regulation of RNA biosynthetic process
KM403_08280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM403_08285	COG1360	Flagellar Motor Protein
KM403_08290	COG2201	protein-glutamate methylesterase activity
KM403_08295	COG0643	Histidine kinase
KM403_08295	COG2198	Histidine kinase
KM403_08300	COG0643	Histidine kinase
KM403_08300	COG2198	Histidine kinase
KM403_08305	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM403_08305	COG1776	CheC inhibitor of MCP methylation
KM403_08320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM403_08340	COG1256	bacterial-type flagellum assembly
KM403_08365	COG1815	bacterial-type flagellum-dependent cell motility
KM403_08370	COG1558	bacterial-type flagellum-dependent cell motility
KM403_08385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM403_08395	COG1157	protein secretion by the type III secretion system
KM403_08435	COG0784	Response regulator, receiver
KM403_08435	COG0835	chemotaxis
KM403_08445	COG0463	Glycosyl transferase, family 2
KM403_08480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM403_08485	COG0741	lytic transglycosylase activity
KM403_08500	COG1776	CheC inhibitor of MCP methylation
KM403_08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM403_08510	COG1338	Plays a role in the flagellum-specific transport system
KM403_08515	COG1987	bacterial-type flagellum assembly
KM403_08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM403_08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM403_08535	COG1419	protein localization to endoplasmic reticulum
KM403_08540	COG4786	Flagellar basal body rod
KM403_08545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM403_08570	COG1309	transcriptional regulator
KM403_08590	COG2329	Antibiotic biosynthesis monooxygenase
KM403_08615	COG0583	DNA-binding transcription factor activity
KM403_08620	COG3842	ATPase activity
KM403_08625	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM403_08635	COG1234	tRNA 3'-trailer cleavage
KM403_08660	COG1686	Belongs to the peptidase S11 family
KM403_08670	COG0406	alpha-ribazole phosphatase activity
KM403_08700	COG0367	asparagine synthase
KM403_08730	COG1802	Transcriptional regulator
KM403_08735	COG0697	spore germination
KM403_08740	COG0523	cobalamin synthesis protein
KM403_08745	COG0701	Predicted permease
KM403_08755	COG0438	transferase activity, transferring glycosyl groups
KM403_08755	COG1216	Glycosyl transferase, family 2
KM403_08760	COG1757	Na H antiporter
KM403_08765	COG0114	fumarate hydratase activity
KM403_08790	COG3340	Belongs to the peptidase S51 family
KM403_08810	COG0785	Cytochrome C biogenesis protein
KM403_08840	COG2733	membrane
KM403_08875	COG1131	(ABC) transporter
KM403_08890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM403_08895	COG0528	UMP kinase activity
KM403_08905	COG1027	Aspartate ammonia-lyase
KM403_08910	COG0281	malic enzyme
KM403_08915	COG4191	Histidine kinase
KM403_08920	COG0784	Response regulator, receiver
KM403_08925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM403_08980	COG1051	belongs to the nudix hydrolase family
KM403_08985	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM403_08995	COG2814	Major facilitator Superfamily
KM403_09010	COG1966	Carbon starvation protein
KM403_09025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_09035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM403_09045	COG2223	nitrite transmembrane transporter activity
KM403_09050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM403_09065	COG2244	polysaccharide biosynthetic process
KM403_09070	COG0733	neurotransmitter:sodium symporter activity
KM403_09080	COG5566	PFAM Mor transcription activator
KM403_09085	COG2323	membrane
KM403_09100	COG2084	Dehydrogenase
KM403_09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM403_09125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM403_09130	COG0028	Belongs to the TPP enzyme family
KM403_09135	COG0440	acetolactate synthase activity
KM403_09140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM403_09150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM403_09175	COG2814	Major facilitator Superfamily
KM403_09180	COG3384	dioxygenase
KM403_09190	COG3279	Response regulator of the LytR AlgR family
KM403_09195	COG0427	acetyl-CoA hydrolase
KM403_09215	COG1073	alpha beta
KM403_09245	COG0535	radical SAM domain protein
KM403_09250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_09270	COG1914	H( )-stimulated, divalent metal cation uptake system
KM403_09285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM403_09315	COG2390	Transcriptional regulator
KM403_09325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_09330	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM403_09345	COG4224	UPF0291 protein
KM403_09365	COG0006	proline dipeptidase activity
KM403_09370	COG2132	Multicopper oxidase
KM403_09385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM403_09400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM403_09415	COG1276	copper resistance
KM403_09415	COG2372	response to copper ion
KM403_09420	COG4549	nuclear export factor GLE1
KM403_09430	COG0697	spore germination
KM403_09435	COG0583	DNA-binding transcription factor activity
KM403_09440	COG1959	2 iron, 2 sulfur cluster binding
KM403_09445	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM403_09450	COG0778	Nitroreductase
KM403_09460	COG0628	permease
KM403_09470	COG1231	oxidoreductase activity
KM403_09475	COG0523	cobalamin synthesis protein
KM403_09490	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_09495	COG2030	dehydratase
KM403_09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_09510	COG0411	ABC transporter
KM403_09530	COG0583	DNA-binding transcription factor activity
KM403_09540	COG1942	4-Oxalocrotonate Tautomerase
KM403_09550	COG1846	Transcriptional regulator
KM403_09560	COG1271	oxidase subunit
KM403_09565	COG1294	oxidase, subunit
KM403_09570	COG4988	ABC transporter
KM403_09575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM403_09595	COG1686	Belongs to the peptidase S11 family
KM403_09610	COG1388	LysM domain
KM403_09610	COG0791	NLP P60 protein
KM403_09625	COG0745	RESPONSE REGULATOR receiver
KM403_09630	COG5002	protein histidine kinase activity
KM403_09640	COG0300	oxidoreductase activity
KM403_09675	COG0460	homoserine dehydrogenase
KM403_09700	COG1316	TRANSCRIPTIONal
KM403_09710	COG0745	RESPONSE REGULATOR receiver
KM403_09715	COG5002	protein histidine kinase activity
KM403_09730	COG1285	pathogenesis
KM403_09735	COG1247	-acetyltransferase
KM403_09755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM403_09765	COG1082	Xylose isomerase domain protein TIM barrel
KM403_09780	COG1279	arginine transmembrane transporter activity
KM403_09790	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM403_09830	COG2002	toxin-antitoxin pair type II binding
KM403_09835	COG1404	Belongs to the peptidase S8 family
KM403_09840	COG0640	Transcriptional regulator
KM403_09845	COG0667	Aldo Keto reductase
KM403_09850	COG2814	Major facilitator Superfamily
KM403_09875	COG0840	transmembrane signaling receptor activity
KM403_09890	COG3949	Membrane
KM403_09895	COG0783	Belongs to the Dps family
KM403_09910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM403_09920	COG1231	oxidoreductase activity
KM403_09930	COG4989	oxidoreductase activity
KM403_09935	COG0523	cobalamin synthesis protein
KM403_09940	COG0456	acetyltransferase
KM403_09995	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM403_09995	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM403_10005	COG0702	epimerase
KM403_10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM403_10025	COG4166	transmembrane transport
KM403_10040	COG0406	alpha-ribazole phosphatase activity
KM403_10050	COG5337	Spore coat protein CotH
KM403_10055	COG1051	belongs to the nudix hydrolase family
KM403_10060	COG0586	Pfam SNARE associated Golgi protein
KM403_10065	COG2244	polysaccharide biosynthetic process
KM403_10075	COG0701	Predicted permease
KM403_10080	COG3689	TIGRFAM TIGR03943 family protein
KM403_10085	COG1607	acyl-coa hydrolase
KM403_10095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM403_10110	COG0702	epimerase
KM403_10115	COG2839	Protein conserved in bacteria
KM403_10120	COG1253	flavin adenine dinucleotide binding
KM403_10135	COG1114	Component of the transport system for branched-chain amino acids
KM403_10140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM403_10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM403_10170	COG1876	peptidase activity
KM403_10180	COG0154	amidase activity
KM403_10185	COG2211	Major facilitator Superfamily
KM403_10205	COG0561	phosphatase activity
KM403_10215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM403_10220	COG4106	trans-aconitate 2-methyltransferase activity
KM403_10235	COG1819	glycosyl
KM403_10240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_10270	COG0456	acetyltransferase
KM403_10320	COG3874	Sporulation protein YtfJ
KM403_10345	COG2226	methyltransferase
KM403_10370	COG0346	lactoylglutathione lyase activity
KM403_10380	COG0604	alcohol dehydrogenase
KM403_10385	COG1595	DNA-templated transcription, initiation
KM403_10410	COG0386	Belongs to the glutathione peroxidase family
KM403_10415	COG1305	Transglutaminase-like
KM403_10420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM403_10425	COG0714	Associated with various cellular activities
KM403_10440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM403_10445	COG1140	nitrate reductase beta subunit
KM403_10450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM403_10455	COG2181	nitrate reductase activity
KM403_10475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM403_10480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM403_10485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM403_10490	COG0303	'Molybdopterin
KM403_10495	COG0314	molybdopterin synthase activity
KM403_10505	COG2223	nitrite transmembrane transporter activity
KM403_10520	COG1648	precorrin-2 dehydrogenase activity
KM403_10530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM403_10530	COG1587	Uroporphyrinogen-III synthase
KM403_10535	COG2146	nitrite reductase [NAD(P)H] activity
KM403_10540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM403_10545	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM403_10580	COG2359	stage V sporulation protein S
KM403_10595	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM403_10610	COG1418	mRNA catabolic process
KM403_10615	COG0488	(ABC) transporter
KM403_10630	COG0629	single-stranded DNA binding
KM403_10645	COG1413	lyase activity
KM403_10660	COG2136	Putative SAM-dependent methyltransferase
KM403_10660	COG2521	methyltransferase
KM403_10665	COG0018	arginyl-trna synthetase
KM403_10690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM403_10710	COG0017	Asparaginyl-tRNA synthetase
KM403_10730	COG1674	ftsk spoiiie
KM403_10800	COG1929	Belongs to the glycerate kinase type-1 family
KM403_10805	COG0471	metal ion transport
KM403_10810	COG0745	RESPONSE REGULATOR receiver
KM403_10815	COG3850	Histidine kinase
KM403_10815	COG5002	protein histidine kinase activity
KM403_10830	COG0733	neurotransmitter:sodium symporter activity
KM403_10855	COG2610	gluconate transmembrane transporter activity
KM403_10860	COG1454	alcohol dehydrogenase
KM403_10865	COG1794	racemase activity, acting on amino acids and derivatives
KM403_10875	COG0456	acetyltransferase
KM403_10890	COG1131	(ABC) transporter
KM403_10905	COG0546	phosphoglycolate phosphatase activity
KM403_10925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM403_10940	COG0768	penicillin binding
KM403_10945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM403_10950	COG0204	Acyl-transferase
KM403_10955	COG1272	protein, Hemolysin III
KM403_10965	COG0805	protein transport
KM403_10975	COG1307	EDD domain protein, DegV family
KM403_10980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM403_10985	COG1999	signal sequence binding
KM403_10990	COG0071	Belongs to the small heat shock protein (HSP20) family
KM403_10995	COG0367	asparagine synthase
KM403_11010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM403_11040	COG1051	belongs to the nudix hydrolase family
KM403_11050	COG0668	transmembrane transport
KM403_11055	COG2203	Gaf domain
KM403_11055	COG4585	Histidine kinase
KM403_11060	COG2197	response regulator
KM403_11070	COG1064	alcohol dehydrogenase
KM403_11095	COG1070	Carbohydrate kinase
KM403_11100	COG1070	Carbohydrate kinase
KM403_11130	COG1125	glycine betaine transport
KM403_11130	COG0517	IMP dehydrogenase activity
KM403_11135	COG1174	glycine betaine transport
KM403_11170	COG1253	flavin adenine dinucleotide binding
KM403_11175	COG1012	belongs to the aldehyde dehydrogenase family
KM403_11180	COG5506	Protein of unknown function (DUF1694)
KM403_11195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM403_11200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM403_11210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM403_11215	COG0456	acetyltransferase
KM403_11220	COG3829	transcription factor binding
KM403_11225	COG1509	lysine 2,3-aminomutase activity
KM403_11265	COG4326	sporulation control protein
KM403_11270	COG0671	phosphoesterase, PA-phosphatase related
KM403_11275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM403_11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM403_11310	COG1715	Restriction endonuclease
KM403_11310	COG1787	Restriction endonuclease
KM403_11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM403_11440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM403_11440	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM403_11445	COG2814	Major facilitator Superfamily
KM403_11450	COG4841	protein insertion into membrane
KM403_11455	COG0372	Belongs to the citrate synthase family
KM403_11460	COG2079	MmgE PrpD family protein
KM403_11465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM403_11470	COG1960	acyl-CoA dehydrogenase activity
KM403_11475	COG2084	Dehydrogenase
KM403_11485	COG1280	lysine exporter protein (LysE YggA)
KM403_11490	COG1024	Enoyl-CoA hydratase
KM403_11505	COG0420	3'-5' exonuclease activity
KM403_11510	COG0419	ATPase involved in DNA repair
KM403_11535	COG2223	nitrite transmembrane transporter activity
KM403_11540	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_11545	COG1169	isochorismate synthase
KM403_11550	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM403_11555	COG1535	isochorismatase
KM403_11555	COG3433	isochorismatase activity
KM403_11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM403_11565	COG3251	PFAM MbtH domain protein
KM403_11570	COG2814	Major facilitator Superfamily
KM403_11585	COG0776	regulation of translation
KM403_11595	COG2318	DinB family
KM403_11605	COG1115	amino acid carrier protein
KM403_11620	COG2329	Antibiotic biosynthesis monooxygenase
KM403_11625	COG1187	pseudouridine synthase activity
KM403_11630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM403_11645	COG0596	Alpha beta hydrolase
KM403_11650	COG2814	Major facilitator Superfamily
KM403_11670	COG2226	methyltransferase
KM403_11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_11750	COG1247	-acetyltransferase
KM403_11780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM403_11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_11800	COG1278	Cold shock
KM403_11815	COG0010	Belongs to the arginase family
KM403_11820	COG0561	phosphatase activity
KM403_11865	COG0583	DNA-binding transcription factor activity
KM403_11870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM403_11885	COG0583	DNA-binding transcription factor activity
KM403_11890	COG2258	MOSC domain
KM403_11905	COG1132	(ABC) transporter
KM403_11910	COG1132	(ABC) transporter
KM403_11930	COG1396	sequence-specific DNA binding
KM403_11955	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM403_11960	COG1595	DNA-templated transcription, initiation
KM403_11985	COG1649	PFAM Uncharacterised BCR, COG1649
KM403_12010	COG2971	BadF BadG BcrA BcrD
KM403_12015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM403_12020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM403_12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_12070	COG1309	transcriptional regulator
KM403_12085	COG1136	(ABC) transporter
KM403_12085	COG0577	efflux transmembrane transporter activity
KM403_12090	COG0500	methyltransferase
KM403_12090	COG3615	Tellurite resistance protein tehB
KM403_12100	COG2226	methyltransferase
KM403_12105	COG3961	Belongs to the TPP enzyme family
KM403_12110	COG1846	Transcriptional regulator
KM403_12150	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM403_12165	COG1595	DNA-templated transcription, initiation
KM403_12175	COG0768	penicillin binding
KM403_12185	COG2367	Beta-lactamase
KM403_12190	COG0671	phosphoesterase, PA-phosphatase related
KM403_12195	COG1609	Transcriptional regulator
KM403_12200	COG2814	Major facilitator Superfamily
KM403_12205	COG0673	inositol 2-dehydrogenase activity
KM403_12215	COG1012	belongs to the aldehyde dehydrogenase family
KM403_12230	COG0191	fructose-bisphosphate aldolase activity
KM403_12235	COG3718	enzyme involved in inositol metabolism
KM403_12260	COG0457	Tetratricopeptide repeat
KM403_12265	COG1476	TRANSCRIPTIONal
KM403_12280	COG1876	peptidase activity
KM403_12300	COG1309	transcriptional regulator
KM403_12305	COG0488	(ABC) transporter
KM403_12320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_12335	COG1252	NADH dehydrogenase
KM403_12340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_12355	COG1131	(ABC) transporter
KM403_12365	COG1309	transcriptional regulator
KM403_12380	COG1960	acyl-CoA dehydrogenase activity
KM403_12385	COG0439	Biotin carboxylase
KM403_12390	COG0511	ligase activity, forming carbon-carbon bonds
KM403_12395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM403_12400	COG1024	Enoyl-CoA hydratase
KM403_12405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM403_12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM403_12420	COG1247	-acetyltransferase
KM403_12425	COG0572	uridine kinase
KM403_12435	COG2318	DinB family
KM403_12440	COG1686	Belongs to the peptidase S11 family
KM403_12465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM403_12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM403_12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM403_12530	COG2814	Major facilitator Superfamily
KM403_12550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM403_12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_12585	COG1063	alcohol dehydrogenase
KM403_12615	COG3773	Cell wall hydrolase
KM403_12625	COG0745	RESPONSE REGULATOR receiver
KM403_12640	COG0488	(ABC) transporter
KM403_12655	COG1136	(ABC) transporter
KM403_12680	COG0460	homoserine dehydrogenase
KM403_12685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_12695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM403_12760	COG2124	cytochrome p450
KM403_12795	COG0561	phosphatase activity
KM403_12805	COG5002	protein histidine kinase activity
KM403_12810	COG0768	penicillin binding
KM403_12815	COG1819	glycosyl
KM403_12820	COG1794	racemase activity, acting on amino acids and derivatives
KM403_12830	COG1122	ATPase activity
KM403_12845	COG2205	protein histidine kinase activity
KM403_12855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM403_12860	COG0604	alcohol dehydrogenase
KM403_12865	COG0768	penicillin binding
KM403_12875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM403_12910	COG0693	protein deglycase activity
KM403_12940	COG2814	Major facilitator Superfamily
KM403_12955	COG0584	glycerophosphoryl diester phosphodiesterase
KM403_12975	COG0697	spore germination
KM403_13000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM403_13010	COG2223	nitrite transmembrane transporter activity
KM403_13025	COG2816	NAD+ diphosphatase activity
KM403_13030	COG0592	DNA-directed DNA polymerase activity
KM403_13035	COG1051	belongs to the nudix hydrolase family
KM403_13070	COG3878	Protein conserved in bacteria
KM403_13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM403_13130	COG0322	excinuclease ABC activity
KM403_13175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM403_13200	COG1011	Hydrolase
KM403_13220	COG0076	glutamate decarboxylase activity
KM403_13235	COG1523	belongs to the glycosyl hydrolase 13 family
KM403_13240	COG3227	Zinc metalloprotease (Elastase)
KM403_13260	COG0201	protein transport
KM403_13270	COG0697	spore germination
KM403_13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_13305	COG4129	membrane
KM403_13310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_13325	COG2959	enzyme of heme biosynthesis
KM403_13345	COG3483	tryptophan 2,3-dioxygenase activity
KM403_13350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM403_13355	COG3844	kynureninase activity
KM403_13360	COG1309	transcriptional regulator
KM403_13390	COG3284	Transcriptional regulator
KM403_13410	COG1349	DNA-binding transcription factor activity
KM403_13430	COG1959	2 iron, 2 sulfur cluster binding
KM403_13445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM403_13450	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM403_13455	COG0022	dehydrogenase e1 component
KM403_13460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM403_13470	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_13475	COG0456	acetyltransferase
KM403_13475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM403_13505	COG4176	ABC-type proline glycine betaine transport system permease component
KM403_13510	COG4175	Glycine betaine
KM403_13510	COG0517	IMP dehydrogenase activity
KM403_13535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM403_13540	COG2153	protein acetylation
KM403_13545	COG3397	chitin binding
KM403_13560	COG2205	protein histidine kinase activity
KM403_13585	COG2333	competence protein COMEC
KM403_13585	COG0658	competence protein
KM403_13635	COG3973	AAA domain
KM403_13650	COG2105	PFAM AIG2 family protein
KM403_13655	COG0514	ATP-dependent DNA helicase (RecQ)
KM403_13675	COG4637	Psort location Cytoplasmic, score
KM403_13700	COG3397	chitin binding
KM403_13715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM403_13720	COG1115	amino acid carrier protein
KM403_13725	COG1012	belongs to the aldehyde dehydrogenase family
KM403_13730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM403_13740	COG3938	Belongs to the proline racemase family
KM403_13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM403_13785	COG0586	Pfam SNARE associated Golgi protein
KM403_13800	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM403_13805	COG0519	Catalyzes the synthesis of GMP from XMP
KM403_13810	COG4166	transmembrane transport
KM403_13820	COG4948	Mandelate Racemase Muconate Lactonizing
KM403_13865	COG2936	dipeptidyl-peptidase activity
KM403_13870	COG5002	protein histidine kinase activity
KM403_13910	COG1164	Oligoendopeptidase f
KM403_13925	COG1307	EDD domain protein, DegV family
KM403_13945	COG2814	Major facilitator Superfamily
KM403_13955	COG1664	Polymer-forming cytoskeletal
KM403_13960	COG0789	Transcriptional regulator
KM403_13965	COG4533	DNA binding
KM403_13970	COG0477	Major facilitator Superfamily
KM403_13970	COG2814	Major facilitator Superfamily
KM403_13990	COG2261	transglycosylase associated protein
KM403_14005	COG2226	methyltransferase
KM403_14040	COG0436	Aminotransferase
KM403_14045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM403_14050	COG5146	pantothenate kinase activity
KM403_14070	COG1131	(ABC) transporter
KM403_14115	COG0628	permease
KM403_14125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM403_14130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM403_14135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM403_14140	COG1116	anion transmembrane transporter activity
KM403_14160	COG2816	NAD+ diphosphatase activity
KM403_14180	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM403_14205	COG0697	spore germination
KM403_14210	COG2318	DinB family
KM403_14230	COG4912	Dna alkylation repair
KM403_14250	COG0861	Integral membrane protein TerC family
KM403_14255	COG1368	sulfuric ester hydrolase activity
KM403_14260	COG0488	(ABC) transporter
KM403_14270	COG1033	growth of symbiont in host cell
KM403_14270	COG2409	Drug exporters of the RND superfamily
KM403_14275	COG1033	growth of symbiont in host cell
KM403_14275	COG2409	Drug exporters of the RND superfamily
KM403_14280	COG1033	growth of symbiont in host cell
KM403_14280	COG2409	Drug exporters of the RND superfamily
KM403_14285	COG1309	transcriptional regulator
KM403_14300	COG0287	Prephenate dehydrogenase
KM403_14305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM403_14310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM403_14315	COG1605	Chorismate mutase
KM403_14315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM403_14350	COG3584	3D domain protein
KM403_14350	COG1388	LysM domain
KM403_14360	COG1595	DNA-templated transcription, initiation
KM403_14385	COG1879	ABC-type sugar transport system periplasmic component
KM403_14395	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM403_14405	COG2390	Transcriptional regulator
KM403_14410	COG1070	Carbohydrate kinase
KM403_14440	COG2329	Antibiotic biosynthesis monooxygenase
KM403_14460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_14470	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM403_14475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM403_14480	COG4187	Peptidase family M20/M25/M40
KM403_14485	COG1414	Transcriptional regulator
KM403_14490	COG0833	amino acid
KM403_14495	COG1690	Belongs to the RtcB family
KM403_14500	COG3239	Fatty acid desaturase
KM403_14505	COG1785	Belongs to the alkaline phosphatase family
KM403_14515	COG3655	Transcriptional regulator
KM403_14530	COG4377	Putative membrane peptidase family (DUF2324)
KM403_14540	COG3279	Response regulator of the LytR AlgR family
KM403_14550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_14555	COG0346	lactoylglutathione lyase activity
KM403_14575	COG0714	Associated with various cellular activities
KM403_14600	COG0463	Glycosyl transferase, family 2
KM403_14625	COG0463	Glycosyl transferase, family 2
KM403_14635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM403_14640	COG0753	catalase activity
KM403_14650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM403_14675	COG0714	Associated with various cellular activities
KM403_14685	COG0778	Nitroreductase
KM403_14690	COG1846	Transcriptional regulator
KM403_14725	COG1725	Transcriptional regulator
KM403_14735	COG1136	(ABC) transporter
KM403_14735	COG0577	efflux transmembrane transporter activity
KM403_14760	COG2207	Transcriptional regulator
KM403_14765	COG0456	acetyltransferase
KM403_14785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_14805	COG0642	Histidine kinase
KM403_14810	COG0745	RESPONSE REGULATOR receiver
KM403_14815	COG0596	Alpha beta hydrolase
KM403_14845	COG0730	response to heat
KM403_14855	COG0833	amino acid
KM403_14865	COG4335	DNA alkylation repair
KM403_14905	COG0768	penicillin binding
KM403_14915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM403_14945	COG1984	allophanate hydrolase subunit 2
KM403_14950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM403_14955	COG1414	Transcriptional regulator
KM403_14970	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM403_14975	COG0640	Transcriptional regulator
KM403_14985	COG1960	acyl-CoA dehydrogenase activity
KM403_15005	COG3314	Sporulation integral membrane protein YlbJ
KM403_15020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM403_15035	COG3848	Pyruvate phosphate dikinase
KM403_15035	COG0574	Belongs to the PEP-utilizing enzyme family
KM403_15040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_15055	COG5577	PFAM Coat F domain
KM403_15060	COG3403	YqcI/YcgG family
KM403_15065	COG1280	lysine exporter protein (LysE YggA)
KM403_15100	COG1063	alcohol dehydrogenase
KM403_15115	COG1027	Aspartate ammonia-lyase
KM403_15120	COG0252	asparaginase activity
KM403_15125	COG1396	sequence-specific DNA binding
KM403_15135	COG0322	excinuclease ABC activity
KM403_15140	COG0531	amino acid
KM403_15145	COG1114	Component of the transport system for branched-chain amino acids
KM403_15150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM403_15160	COG0281	malic enzyme
KM403_15175	COG0531	amino acid
KM403_15185	COG0784	Response regulator, receiver
KM403_15195	COG2066	Belongs to the glutaminase family
KM403_15200	COG1115	amino acid carrier protein
KM403_15230	COG0737	Belongs to the 5'-nucleotidase family
KM403_15235	COG0753	catalase activity
KM403_15240	COG2267	carboxylic ester hydrolase activity
KM403_15245	COG1335	isochorismatase
KM403_15265	COG0583	DNA-binding transcription factor activity
KM403_15270	COG1846	Transcriptional regulator
KM403_15310	COG0415	Belongs to the DNA photolyase family
KM403_15315	COG0288	reversible hydration of carbon dioxide
KM403_15325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM403_15330	COG5609	conserved protein (DUF2294)
KM403_15345	COG1575	Belongs to the MenA family. Type 1 subfamily
KM403_15350	COG2267	carboxylic ester hydrolase activity
KM403_15355	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM403_15360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM403_15365	COG1121	(ABC) transporter
KM403_15395	COG0798	PFAM Bile acid sodium symporter
KM403_15400	COG0346	lactoylglutathione lyase activity
KM403_15405	COG0640	Transcriptional regulator
KM403_15420	COG0443	Heat shock 70 kDa protein
KM403_15435	COG1522	sequence-specific DNA binding
KM403_15450	COG0346	lactoylglutathione lyase activity
KM403_15475	COG2169	Transcriptional regulator
KM403_15520	COG2814	Major facilitator Superfamily
KM403_15545	COG0745	RESPONSE REGULATOR receiver
KM403_15550	COG5002	protein histidine kinase activity
KM403_15550	COG3850	Histidine kinase
KM403_15575	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM403_15595	COG1476	TRANSCRIPTIONal
KM403_15610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_15615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM403_15625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_15630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM403_15645	COG1136	(ABC) transporter
KM403_15650	COG0577	efflux transmembrane transporter activity
KM403_15665	COG3850	Histidine kinase
KM403_15665	COG5002	protein histidine kinase activity
KM403_15675	COG2364	Membrane
KM403_15680	COG1846	Transcriptional regulator
KM403_15690	COG2808	Putative FMN-binding domain
KM403_15695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_15700	COG2271	Major facilitator Superfamily
KM403_15705	COG1556	Lactate utilization protein
KM403_15710	COG1139	Iron-sulfur cluster binding protein
KM403_15720	COG0583	DNA-binding transcription factor activity
KM403_15730	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM403_15755	COG0738	Major facilitator superfamily
KM403_15760	COG0673	inositol 2-dehydrogenase activity
KM403_15765	COG0561	phosphatase activity
KM403_15775	COG1609	Transcriptional regulator
KM403_15780	COG0457	Tetratricopeptide repeat
KM403_15800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM403_15830	COG0534	Mate efflux family protein
KM403_15850	COG2814	Major facilitator Superfamily
KM403_15855	COG1309	transcriptional regulator
KM403_15870	COG0814	amino acid
KM403_15875	COG1760	l-serine dehydratase
KM403_15880	COG1760	l-serine dehydratase
KM403_15890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM403_15895	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM403_15905	COG1335	isochorismatase
KM403_15910	COG1522	sequence-specific DNA binding
KM403_15915	COG0531	amino acid
KM403_15930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM403_15950	COG1595	DNA-templated transcription, initiation
KM403_15965	COG0662	Cupin 2, conserved barrel domain protein
KM403_15970	COG2207	Transcriptional regulator
KM403_15970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_16020	COG0477	Major facilitator Superfamily
KM403_16030	COG1846	Transcriptional regulator
KM403_16035	COG2814	Major facilitator Superfamily
KM403_16045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM403_16050	COG1131	(ABC) transporter
KM403_16070	COG2076	Multidrug Resistance protein
KM403_16075	COG1309	transcriptional regulator
KM403_16085	COG2031	fatty acid transporter
KM403_16095	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM403_16125	COG1122	ATPase activity
KM403_16130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM403_16145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM403_16150	COG1288	antiporter activity
KM403_16155	COG2356	endonuclease I
KM403_16170	COG3620	sequence-specific DNA binding
KM403_16175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM403_16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM403_16185	COG0124	histidyl-tRNA synthetase
KM403_16200	COG1733	regulation of RNA biosynthetic process
KM403_16205	COG0778	Nitroreductase
KM403_16225	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_16235	COG1131	(ABC) transporter
KM403_16260	COG1011	Hydrolase
KM403_16270	COG2365	Tyrosine phosphatase family
KM403_16295	COG0346	lactoylglutathione lyase activity
KM403_16300	COG1940	carbohydrate kinase activity
KM403_16305	COG0738	Major facilitator superfamily
KM403_16310	COG0110	maltose O-acetyltransferase activity
KM403_16320	COG0577	efflux transmembrane transporter activity
KM403_16320	COG1136	(ABC) transporter
KM403_16335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM403_16340	COG0628	permease
KM403_16360	COG2226	methyltransferase
KM403_16370	COG0477	Major facilitator Superfamily
KM403_16400	COG1253	flavin adenine dinucleotide binding
KM403_16405	COG0789	Transcriptional regulator
KM403_16410	COG0697	spore germination
KM403_16415	COG1357	PFAM Pentapeptide repeats (8 copies)
KM403_16420	COG3813	Protein conserved in bacteria
KM403_16425	COG2706	6-phosphogluconolactonase activity
KM403_16430	COG1070	Carbohydrate kinase
KM403_16440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM403_16445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM403_16455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM403_16460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM403_16465	COG0604	alcohol dehydrogenase
KM403_16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM403_16480	COG3321	synthase
KM403_16480	COG0604	alcohol dehydrogenase
KM403_16485	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_16510	COG0656	L-ascorbic acid biosynthetic process
KM403_16515	COG2814	Major facilitator Superfamily
KM403_16530	COG0346	lactoylglutathione lyase activity
KM403_16535	COG0814	amino acid
KM403_16560	COG1393	Belongs to the ArsC family
KM403_16565	COG1733	regulation of RNA biosynthetic process
KM403_16570	COG2188	Transcriptional regulator
KM403_16580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM403_16585	COG1733	regulation of RNA biosynthetic process
KM403_16590	COG1733	regulation of RNA biosynthetic process
KM403_16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_16625	COG0384	phenazine biosynthesis protein PhzF
KM403_16635	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_16645	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_16655	COG1733	regulation of RNA biosynthetic process
KM403_16690	COG1191	sigma factor activity
KM403_16705	COG1309	transcriptional regulator
KM403_16725	COG3152	Membrane
KM403_16750	COG1151	hydroxylamine reductase activity
KM403_16760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_16765	COG3757	hydrolase, family 25
KM403_16765	COG3409	Peptidoglycan-binding domain 1 protein
KM403_16800	COG2072	flavoprotein involved in K transport
KM403_16835	COG0604	alcohol dehydrogenase
KM403_16840	COG1113	amino acid transport
KM403_16845	COG2814	Major facilitator Superfamily
KM403_16875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM403_16880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM403_16900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_16915	COG3739	integral membrane protein
KM403_16920	COG0384	phenazine biosynthesis protein PhzF
KM403_16950	COG0583	DNA-binding transcription factor activity
KM403_16970	COG1193	negative regulation of DNA recombination
KM403_16995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM403_17025	COG0584	glycerophosphoryl diester phosphodiesterase
KM403_17050	COG0640	Transcriptional regulator
KM403_17055	COG0604	alcohol dehydrogenase
KM403_17075	COG2808	Putative FMN-binding domain
KM403_17080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM403_17090	COG0385	Bile acid
KM403_17095	COG0277	FAD linked oxidase domain protein
KM403_17125	COG1216	Glycosyl transferase, family 2
KM403_17130	COG1024	Enoyl-CoA hydratase
KM403_17140	COG1285	pathogenesis
KM403_17155	COG2514	catechol 2,3-dioxygenase activity
KM403_17160	COG2720	vancomycin resistance protein
KM403_17200	COG0716	FMN binding
KM403_17230	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_17240	COG0165	Argininosuccinate lyase
KM403_17255	COG4145	pantothenate transmembrane transporter activity
KM403_17265	COG1012	belongs to the aldehyde dehydrogenase family
KM403_17270	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_17280	COG1657	PFAM Prenyltransferase squalene oxidase
KM403_17285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM403_17290	COG2962	Rard protein
KM403_17295	COG3326	Membrane
KM403_17310	COG0489	protein tyrosine kinase activity
KM403_17320	COG0314	molybdopterin synthase activity
KM403_17325	COG0303	'Molybdopterin
KM403_17330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM403_17335	COG2116	formate transmembrane transporter activity
KM403_17345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM403_17350	COG5609	conserved protein (DUF2294)
KM403_17355	COG2427	Protein of unknown function (DUF1641)
KM403_17360	COG3383	formate dehydrogenase (NAD+) activity
KM403_17365	COG0697	spore germination
KM403_17405	COG2226	methyltransferase
KM403_17410	COG4166	transmembrane transport
KM403_17415	COG4166	transmembrane transport
KM403_17420	COG4166	transmembrane transport
KM403_17425	COG1301	dicarboxylic acid transport
KM403_17430	COG1316	TRANSCRIPTIONal
KM403_17440	COG1595	DNA-templated transcription, initiation
KM403_17460	COG1131	(ABC) transporter
KM403_17470	COG0673	inositol 2-dehydrogenase activity
KM403_17475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM403_17480	COG0187	DNA topoisomerase II activity
KM403_17485	COG1832	CoA-binding protein
KM403_17490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM403_17495	COG0745	RESPONSE REGULATOR receiver
KM403_17510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM403_17515	COG4841	protein insertion into membrane
KM403_17520	COG0824	Thioesterase
KM403_17550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM403_17560	COG2274	protein secretion by the type I secretion system
KM403_17565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM403_17605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM403_17620	COG0183	Belongs to the thiolase family
KM403_17625	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_17630	COG1268	BioY protein
KM403_17635	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_17685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_17695	COG5002	protein histidine kinase activity
KM403_17700	COG0400	carboxylic ester hydrolase activity
KM403_17705	COG0346	lactoylglutathione lyase activity
KM403_17710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM403_17715	COG0069	glutamate synthase activity
KM403_17720	COG1902	pentaerythritol trinitrate reductase activity
KM403_17725	COG1329	Transcriptional regulator
KM403_17730	COG0010	Belongs to the arginase family
KM403_17755	COG2226	methyltransferase
KM403_17810	COG4846	Membrane protein involved in cytochrome C biogenesis
KM403_17815	COG0785	Cytochrome C biogenesis protein
KM403_17825	COG0583	DNA-binding transcription factor activity
KM403_17830	COG1380	Effector of murein hydrolase LrgA
KM403_17835	COG1346	cytolysis
KM403_17860	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM403_17860	COG3409	Peptidoglycan-binding domain 1 protein
KM403_17875	COG1132	(ABC) transporter
KM403_17880	COG1132	(ABC) transporter
KM403_17910	COG3639	organic phosphonate transmembrane transporter activity
KM403_17915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM403_17935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM403_17955	COG1695	Transcriptional regulator
KM403_17995	COG3409	Peptidoglycan-binding domain 1 protein
KM403_17995	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM403_17995	COG1388	LysM domain
KM403_18000	COG4824	toxin secretion phage lysis holin
KM403_18155	COG1595	DNA-templated transcription, initiation
KM403_18200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM403_18280	COG1396	sequence-specific DNA binding
KM403_18305	COG0174	glutamine synthetase
KM403_18310	COG0789	Transcriptional regulator
KM403_18315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM403_18325	COG2860	membrane
KM403_18335	COG0464	growth
KM403_18365	COG1388	LysM domain
KM403_18365	COG3584	3D domain protein
KM403_18370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM403_18370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM403_18370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM403_18375	COG1105	Belongs to the carbohydrate kinase PfkB family
KM403_18380	COG1349	DNA-binding transcription factor activity
KM403_18390	COG2322	membrane
KM403_18400	COG1113	amino acid transport
KM403_18415	COG1408	metallophosphoesterase
KM403_18420	COG2116	formate transmembrane transporter activity
KM403_18430	COG2217	Heavy metal translocating P-type atpase
KM403_18435	COG2608	mercury ion transmembrane transporter activity
KM403_18440	COG1937	Protein conserved in bacteria
KM403_18450	COG2819	hydrolase of the alpha beta superfamily
KM403_18455	COG1120	ATPase activity
KM403_18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_18465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_18475	COG0708	Exodeoxyribonuclease III
KM403_18480	COG2169	Transcriptional regulator
KM403_18485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM403_18490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM403_18500	COG2364	Membrane
KM403_18515	COG2267	carboxylic ester hydrolase activity
KM403_18520	COG0346	lactoylglutathione lyase activity
KM403_18525	COG5001	Diguanylate cyclase
KM403_18525	COG3300	MHYT domain
KM403_18540	COG1346	cytolysis
KM403_18545	COG1380	Effector of murein hydrolase LrgA
KM403_18550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM403_18555	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM403_18555	COG0596	Alpha beta hydrolase
KM403_18560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM403_18580	COG1404	Belongs to the peptidase S8 family
KM403_18585	COG3773	Cell wall hydrolase
KM403_18590	COG0562	UDP-galactopyranose mutase
KM403_18595	COG1368	sulfuric ester hydrolase activity
KM403_18600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM403_18610	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM403_18635	COG1131	(ABC) transporter
KM403_18655	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM403_18660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM403_18665	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM403_18670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM403_18670	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM403_18680	COG2359	stage V sporulation protein S
KM403_18685	COG1692	metallophosphoesterase
KM403_18710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM403_18715	COG1426	Protein conserved in bacteria
KM403_18730	COG0300	oxidoreductase activity
KM403_18735	COG0612	Peptidase, M16
KM403_18740	COG0612	Peptidase, M16
KM403_18745	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM403_18755	COG3845	ABC transporter
KM403_18760	COG1744	ABC transporter substrate-binding protein PnrA-like
KM403_18765	COG2188	Transcriptional regulator
KM403_18770	COG1674	ftsk spoiiie
KM403_18780	COG0740	serine-type endopeptidase activity
KM403_18785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM403_18795	COG0527	aspartate kinase activity
KM403_18800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM403_18805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM403_18810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM403_18815	COG1873	PFAM PRC-barrel domain
KM403_18820	COG0612	Peptidase, M16
KM403_18825	COG0726	polysaccharide deacetylase
KM403_18840	COG0196	riboflavin kinase activity
KM403_18845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM403_18855	COG1550	Protein conserved in bacteria
KM403_18865	COG1358	cellular component organization or biogenesis
KM403_18870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM403_18875	COG0195	Participates in both transcription termination and antitermination
KM403_18895	COG0750	zinc metalloprotease
KM403_18905	COG4589	Belongs to the CDS family
KM403_18910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM403_18920	COG0528	UMP kinase activity
KM403_18950	COG4974	Belongs to the 'phage' integrase family
KM403_18960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM403_18970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM403_19010	COG1837	Belongs to the UPF0109 family
KM403_19020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM403_19030	COG0552	protein localization to endoplasmic reticulum
KM403_19035	COG1196	nuclear chromosome segregation
KM403_19045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM403_19050	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_19055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM403_19070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM403_19075	COG1461	Dihydroxyacetone kinase
KM403_19080	COG1302	Protein conserved in bacteria
KM403_19095	COG1564	THIamine pyrophosphokinase
KM403_19100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM403_19105	COG1162	GTPase activity
KM403_19110	COG0515	serine threonine protein kinase
KM403_19110	COG2815	serine threonine protein kinase
KM403_19115	COG0631	protein serine/threonine phosphatase activity
KM403_19125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM403_19125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM403_19135	COG0242	peptide deformylase activity
KM403_19140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM403_19145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM403_19165	COG1561	YicC-like family, N-terminal region
KM403_19170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM403_19180	COG0006	proline dipeptidase activity
KM403_19195	COG3069	C4-dicarboxylate transmembrane transporter activity
KM403_19260	COG0564	pseudouridine synthase activity
KM403_19280	COG3599	regulation of cell shape
KM403_19285	COG2302	S4 RNA-binding domain
KM403_19290	COG0762	integral membrane protein
KM403_19300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM403_19305	COG1496	oxidoreductase activity
KM403_19310	COG1873	PFAM PRC-barrel domain
KM403_19315	COG1191	sigma factor activity
KM403_19320	COG1191	sigma factor activity
KM403_19330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM403_19335	COG0849	cell division
KM403_19340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM403_19345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM403_19355	COG0772	Belongs to the SEDS family
KM403_19370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM403_19375	COG0768	penicillin binding
KM403_19380	COG0768	penicillin binding
KM403_19385	COG4839	cell division protein FtsL
KM403_19400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM403_19415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM403_19420	COG1399	metal-binding, possibly nucleic acid-binding protein
KM403_19470	COG4824	toxin secretion phage lysis holin
KM403_19555	COG4626	Terminase
KM403_19555	COG1802	Transcriptional regulator
KM403_19645	COG0756	dUTP diphosphatase activity
KM403_19660	COG1191	sigma factor activity
KM403_19685	COG1484	DNA-dependent DNA replication
KM403_19715	COG1396	sequence-specific DNA binding
KM403_19730	COG1396	sequence-specific DNA binding
KM403_19745	COG0582	viral genome integration into host DNA
KM403_19755	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM403_19760	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM403_19765	COG3314	Sporulation integral membrane protein YlbJ
KM403_19775	COG0742	ribosomal rna small subunit methyltransferase
KM403_19790	COG3679	Belongs to the UPF0342 family
KM403_19795	COG0406	alpha-ribazole phosphatase activity
KM403_19810	COG2340	Cysteine-rich secretory protein family
KM403_19825	COG3336	cytochrome c oxidase
KM403_19860	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM403_19865	COG0772	Belongs to the SEDS family
KM403_19875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM403_19880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM403_19890	COG4896	Protein conserved in bacteria
KM403_19905	COG1217	gtp-binding protein TYPA
KM403_19915	COG0483	inositol monophosphate 1-phosphatase activity
KM403_19935	COG1982	Orn Lys Arg decarboxylase major
KM403_19980	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM403_19985	COG0022	dehydrogenase e1 component
KM403_19990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM403_20000	COG0242	peptide deformylase activity
KM403_20005	COG0561	phosphatase activity
KM403_20015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM403_20020	COG0569	domain protein
KM403_20040	COG0583	DNA-binding transcription factor activity
KM403_20045	COG0517	IMP dehydrogenase activity
KM403_20055	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM403_20065	COG4703	Protein of unknown function (DUF1797)
KM403_20080	COG2200	EAL domain
KM403_20085	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_20090	COG1408	metallophosphoesterase
KM403_20100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM403_20135	COG2814	Major facilitator Superfamily
KM403_20155	COG3209	COG3209 Rhs family protein
KM403_20165	COG2205	protein histidine kinase activity
KM403_20175	COG0436	Aminotransferase
KM403_20180	COG1609	Transcriptional regulator
KM403_20185	COG3833	ABC-type maltose transport systems, permease component
KM403_20190	COG1175	transmembrane transport
KM403_20195	COG2182	Extracellular solute-binding protein
KM403_20205	COG0366	Alpha amylase catalytic
KM403_20210	COG3842	ATPase activity
KM403_20250	COG0183	Belongs to the thiolase family
KM403_20285	COG1695	Transcriptional regulator
KM403_20290	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_20300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM403_20310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM403_20315	COG0436	Aminotransferase
KM403_20335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM403_20355	COG2199	diguanylate cyclase activity
KM403_20360	COG0778	Nitroreductase
KM403_20385	COG1263	PTS System
KM403_20385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM403_20385	COG2190	(PTS) system
KM403_20390	COG3711	transcriptional antiterminator
KM403_20400	COG2188	Transcriptional regulator
KM403_20410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM403_20435	COG1547	Domain of unknown function (DUF309)
KM403_20440	COG0456	acetyltransferase
KM403_20445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM403_20450	COG4086	secreted protein
KM403_20455	COG0561	phosphatase activity
KM403_20460	COG0697	spore germination
KM403_20475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_20500	COG0733	neurotransmitter:sodium symporter activity
KM403_20520	COG1686	Belongs to the peptidase S11 family
KM403_20525	COG1725	Transcriptional regulator
KM403_20530	COG1131	(ABC) transporter
KM403_20545	COG1846	Transcriptional regulator
KM403_20560	COG0598	Magnesium transport protein CorA
KM403_20585	COG4974	Belongs to the 'phage' integrase family
KM403_20595	COG0735	belongs to the Fur family
KM403_20600	COG1300	Membrane
KM403_20620	COG0667	Aldo Keto reductase
KM403_20625	COG0656	L-ascorbic acid biosynthetic process
KM403_20630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM403_20630	COG0456	acetyltransferase
KM403_20640	COG1525	nuclease
KM403_20640	COG0737	Belongs to the 5'-nucleotidase family
KM403_20640	COG4085	toxin activity
KM403_20650	COG0596	Alpha beta hydrolase
KM403_20655	COG2056	Na+-H+ antiporter family
KM403_20660	COG1609	Transcriptional regulator
KM403_20665	COG0456	acetyltransferase
KM403_20670	COG1073	alpha beta
KM403_20685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM403_20685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM403_20690	COG0307	riboflavin synthase, alpha
KM403_20715	COG4106	trans-aconitate 2-methyltransferase activity
KM403_20720	COG1073	alpha beta
KM403_20720	COG2226	methyltransferase
KM403_20735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM403_20745	COG1757	Na H antiporter
KM403_20750	COG0737	Belongs to the 5'-nucleotidase family
KM403_20760	COG1522	sequence-specific DNA binding
KM403_20780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM403_20790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM403_20805	COG0300	oxidoreductase activity
KM403_20815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM403_20820	COG1760	l-serine dehydratase
KM403_20825	COG1760	l-serine dehydratase
KM403_20845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM403_20855	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM403_20860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_20875	COG1376	ErfK ybiS ycfS ynhG family protein
KM403_20880	COG4129	membrane
KM403_20885	COG1126	abc transporter atp-binding protein
KM403_20890	COG0765	amino acid transport
KM403_20895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM403_20915	COG0772	Belongs to the SEDS family
KM403_20920	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM403_20925	COG0022	dehydrogenase e1 component
KM403_20930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM403_20935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM403_20950	COG0280	phosphate acetyltransferase
KM403_20955	COG3290	protein histidine kinase activity
KM403_20955	COG3829	transcription factor binding
KM403_20965	COG0584	glycerophosphoryl diester phosphodiesterase
KM403_20970	COG3093	addiction module antidote protein HigA
KM403_20980	COG0745	RESPONSE REGULATOR receiver
KM403_20985	COG0750	zinc metalloprotease
KM403_20990	COG0497	DNA recombination
KM403_21000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM403_21010	COG0142	geranyltranstransferase activity
KM403_21035	COG1302	Protein conserved in bacteria
KM403_21040	COG0439	Biotin carboxylase
KM403_21045	COG0511	ligase activity, forming carbon-carbon bonds
KM403_21090	COG3854	ATPases associated with a variety of cellular activities
KM403_21115	COG0006	proline dipeptidase activity
KM403_21130	COG3872	metal-dependent enzyme
KM403_21140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM403_21160	COG0095	Lipoate-protein ligase
KM403_21165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_21170	COG1609	Transcriptional regulator
KM403_21180	COG2076	Multidrug Resistance protein
KM403_21185	COG2076	Multidrug Resistance protein
KM403_21220	COG1131	(ABC) transporter
KM403_21225	COG1725	Transcriptional regulator
KM403_21255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM403_21310	COG4970	Tfp pilus assembly protein FimT
KM403_21320	COG1459	type II secretion system
KM403_21325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM403_21375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM403_21380	COG1410	methionine synthase
KM403_21380	COG0646	methionine synthase
KM403_21385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM403_21385	COG0646	methionine synthase
KM403_21390	COG0626	cystathionine gamma-synthase activity
KM403_21395	COG0626	cystathionine gamma-synthase activity
KM403_21415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_21425	COG1940	carbohydrate kinase activity
KM403_21430	COG4483	Protein conserved in bacteria
KM403_21435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM403_21440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM403_21445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM403_21450	COG0704	Plays a role in the regulation of phosphate uptake
KM403_21460	COG0581	inorganic phosphate transmembrane transporter activity
KM403_21465	COG0573	inorganic phosphate transmembrane transporter activity
KM403_21470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM403_21475	COG0768	penicillin binding
KM403_21480	COG0477	Major facilitator Superfamily
KM403_21485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM403_21510	COG0735	belongs to the Fur family
KM403_21515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM403_21520	COG1121	(ABC) transporter
KM403_21525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_21555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM403_21560	COG2384	SAM-dependent methyltransferase
KM403_21565	COG2010	Cytochrome c
KM403_21570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM403_21575	COG0358	DNA primase activity
KM403_21585	COG0517	IMP dehydrogenase activity
KM403_21600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM403_21605	COG0295	cytidine deaminase activity
KM403_21610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM403_21620	COG1480	7TM receptor with intracellular HD hydrolase
KM403_21625	COG1702	phosphate starvation-inducible protein PhoH
KM403_21640	COG1610	YqeY-like protein
KM403_21645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM403_21650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM403_21655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM403_21685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM403_21690	COG1733	regulation of RNA biosynthetic process
KM403_21715	COG1466	dna polymerase III delta subunit
KM403_21725	COG2333	competence protein COMEC
KM403_21725	COG0658	competence protein
KM403_21730	COG2131	deaminase
KM403_21735	COG1555	photosystem II stabilization
KM403_21735	COG1596	polysaccharide export
KM403_21740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM403_21745	COG2226	methyltransferase
KM403_21750	COG0799	negative regulation of ribosome biogenesis
KM403_21755	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM403_21765	COG1534	Rna-binding protein
KM403_21775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM403_21780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM403_21805	COG1595	DNA-templated transcription, initiation
KM403_21815	COG0778	Nitroreductase
KM403_21820	COG2357	RelA SpoT domain protein
KM403_21830	COG1785	Belongs to the alkaline phosphatase family
KM403_21840	COG2267	carboxylic ester hydrolase activity
KM403_21875	COG1404	Belongs to the peptidase S8 family
KM403_21880	COG3186	Phenylalanine-4-hydroxylase
KM403_21895	COG2259	Doxx family
KM403_21935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_21945	COG1454	alcohol dehydrogenase
KM403_21945	COG1012	belongs to the aldehyde dehydrogenase family
KM403_21950	COG0626	cystathionine gamma-synthase activity
KM403_21955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM403_21980	COG0768	penicillin binding
KM403_21995	COG0826	peptidase U32
KM403_22000	COG0826	peptidase U32
KM403_22005	COG4122	O-methyltransferase activity
KM403_22010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM403_22030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM403_22040	COG0628	permease
KM403_22060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM403_22070	COG0482	sulfurtransferase activity
KM403_22075	COG1104	cysteine desulfurase activity
KM403_22080	COG1959	2 iron, 2 sulfur cluster binding
KM403_22085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM403_22095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM403_22120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM403_22130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM403_22130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM403_22135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM403_22140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM403_22140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM403_22150	COG2244	polysaccharide biosynthetic process
KM403_22155	COG2323	membrane
KM403_22165	COG1862	Preprotein translocase
KM403_22195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM403_22205	COG0697	spore germination
KM403_22210	COG0697	spore germination
KM403_22215	COG0640	Transcriptional regulator
KM403_22240	COG0157	Belongs to the NadC ModD family
KM403_22245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM403_22250	COG1104	cysteine desulfurase activity
KM403_22255	COG1827	regulation of RNA biosynthetic process
KM403_22260	COG2258	MOSC domain
KM403_22265	COG0077	Prephenate dehydratase
KM403_22270	COG0577	efflux transmembrane transporter activity
KM403_22275	COG0577	efflux transmembrane transporter activity
KM403_22280	COG1136	(ABC) transporter
KM403_22290	COG0745	RESPONSE REGULATOR receiver
KM403_22295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM403_22300	COG3290	protein histidine kinase activity
KM403_22310	COG2868	ribosomal protein
KM403_22320	COG1530	ribonuclease E activity
KM403_22325	COG1994	Peptidase M50
KM403_22330	COG0739	heme binding
KM403_22335	COG2894	cell division
KM403_22355	COG1077	Cell shape determining protein MreB Mrl
KM403_22375	COG0285	dihydrofolate synthase activity
KM403_22380	COG0525	valine-tRNA ligase activity
KM403_22390	COG1388	LysM domain
KM403_22400	COG0113	porphobilinogen synthase activity
KM403_22405	COG1587	Uroporphyrinogen-III synthase
KM403_22415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM403_22425	COG1846	Transcriptional regulator
KM403_22430	COG1764	response to oxidative stress
KM403_22445	COG0470	DNA polymerase III
KM403_22445	COG1067	ATP-dependent peptidase activity
KM403_22490	COG0622	Phosphoesterase
KM403_22505	COG5401	PFAM Sporulation and spore germination
KM403_22525	COG1309	transcriptional regulator
KM403_22540	COG2197	response regulator
KM403_22545	COG2233	PERMEase
KM403_22555	COG0402	S-adenosylhomocysteine deaminase activity
KM403_22560	COG0402	S-adenosylhomocysteine deaminase activity
KM403_22570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM403_22580	COG0444	Belongs to the ABC transporter superfamily
KM403_22585	COG4608	Belongs to the ABC transporter superfamily
KM403_22590	COG3275	phosphorelay sensor kinase activity
KM403_22595	COG3279	Response regulator of the LytR AlgR family
KM403_22610	COG1983	PspC domain protein
KM403_22615	COG1396	sequence-specific DNA binding
KM403_22620	COG0697	spore germination
KM403_22630	COG1959	2 iron, 2 sulfur cluster binding
KM403_22635	COG1668	transmembrane transport
KM403_22640	COG4152	abc transporter atp-binding protein
KM403_22645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM403_22655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM403_22660	COG1876	peptidase activity
KM403_22665	COG0824	Thioesterase
KM403_22670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM403_22675	COG1053	succinate dehydrogenase
KM403_22680	COG2009	succinate dehydrogenase
KM403_22685	COG1719	4-vinyl reductase, 4VR
KM403_22695	COG3118	belongs to the thioredoxin family
KM403_22700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM403_22705	COG2086	electron transfer activity
KM403_22710	COG1024	Enoyl-CoA hydratase
KM403_22715	COG1309	transcriptional regulator
KM403_22720	COG0318	PFAM AMP-dependent synthetase and ligase
KM403_22740	COG2318	DinB family
KM403_22765	COG1131	(ABC) transporter
KM403_22770	COG2205	protein histidine kinase activity
KM403_22775	COG0745	RESPONSE REGULATOR receiver
KM403_22785	COG4895	conserved protein (DUF2196)
KM403_22790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM403_22805	COG4509	Sortase family
KM403_22810	COG1120	ATPase activity
KM403_22825	COG5386	Cell surface protein
KM403_22835	COG5386	Cell surface protein
KM403_22840	COG1114	Component of the transport system for branched-chain amino acids
KM403_22845	COG1187	pseudouridine synthase activity
KM403_22855	COG1796	DNA polymerase
KM403_22855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM403_22860	COG1286	toxin biosynthetic process
KM403_22905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM403_22915	COG1418	mRNA catabolic process
KM403_22940	COG2814	Major facilitator Superfamily
KM403_22945	COG1566	PFAM secretion protein HlyD family protein
KM403_22950	COG1309	transcriptional regulator
KM403_22955	COG1363	Peptidase, m42
KM403_22980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM403_22990	COG1484	DNA-dependent DNA replication
KM403_22995	COG3611	Membrane attachment protein
KM403_23005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM403_23010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM403_23015	COG0237	dephospho-CoA kinase activity
KM403_23020	COG1971	Probably functions as a manganese efflux pump
KM403_23030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM403_23030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM403_23035	COG5002	protein histidine kinase activity
KM403_23040	COG0745	RESPONSE REGULATOR receiver
KM403_23060	COG0538	isocitrate dehydrogenase activity
KM403_23065	COG0372	Belongs to the citrate synthase family
KM403_23075	COG0628	permease
KM403_23080	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM403_23105	COG1725	Transcriptional regulator
KM403_23110	COG0281	malic enzyme
KM403_23115	COG0587	DNA-directed DNA polymerase activity
KM403_23130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM403_23150	COG4109	DRTGG domain
KM403_23165	COG0006	proline dipeptidase activity
KM403_23200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_23205	COG0662	Cupin 2, conserved barrel domain protein
KM403_23215	COG1476	TRANSCRIPTIONal
KM403_23230	COG1028	Short-chain dehydrogenase reductase Sdr
KM403_23235	COG0589	response to stress
KM403_23275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_23295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM403_23300	COG0827	DNA restriction-modification system
KM403_23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM403_23310	COG3874	Sporulation protein YtfJ
KM403_23325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM403_23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM403_23350	COG1104	cysteine desulfurase activity
KM403_23360	COG0583	DNA-binding transcription factor activity
KM403_23365	COG0697	spore germination
KM403_23375	COG1956	GAF domain-containing protein
KM403_23380	COG0626	cystathionine gamma-synthase activity
KM403_23410	COG1595	DNA-templated transcription, initiation
KM403_23420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM403_23425	COG0454	-acetyltransferase
KM403_23430	COG0517	IMP dehydrogenase activity
KM403_23435	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM403_23445	COG0745	RESPONSE REGULATOR receiver
KM403_23455	COG0666	response to abiotic stimulus
KM403_23490	COG1609	Transcriptional regulator
KM403_23495	COG4851	CamS sex pheromone cAM373 precursor
KM403_23500	COG3118	belongs to the thioredoxin family
KM403_23510	COG2309	aminopeptidase activity
KM403_23530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_23545	COG1674	ftsk spoiiie
KM403_23555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM403_23560	COG4848	Belongs to the UPF0354 family
KM403_23565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM403_23570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM403_23575	COG1363	Peptidase, m42
KM403_23585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_23600	COG0510	thiamine kinase activity
KM403_23605	COG1523	belongs to the glycosyl hydrolase 13 family
KM403_23620	COG1349	DNA-binding transcription factor activity
KM403_23625	COG1187	pseudouridine synthase activity
KM403_23630	COG2244	polysaccharide biosynthetic process
KM403_23635	COG2081	HI0933 family
KM403_23640	COG2814	Major facilitator Superfamily
KM403_23650	COG3832	glyoxalase III activity
KM403_23670	COG1329	Transcriptional regulator
KM403_23680	COG4975	Glucose uptake
KM403_23695	COG0314	molybdopterin synthase activity
KM403_23700	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM403_23705	COG0303	'Molybdopterin
KM403_23715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM403_23740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM403_23750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM403_23795	COG2814	Major facilitator Superfamily
KM403_23800	COG0475	glutathione-regulated potassium exporter activity
KM403_23805	COG0490	domain, Protein
KM403_23810	COG0582	viral genome integration into host DNA
KM403_23820	COG1136	(ABC) transporter
KM403_23840	COG1242	4 iron, 4 sulfur cluster binding
KM403_23845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM403_23850	COG1131	(ABC) transporter
KM403_23860	COG1794	racemase activity, acting on amino acids and derivatives
KM403_23880	COG2267	carboxylic ester hydrolase activity
KM403_23885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM403_23890	COG0671	phosphoesterase, PA-phosphatase related
KM403_23895	COG0438	transferase activity, transferring glycosyl groups
KM403_23905	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM403_23955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM403_23960	COG5002	protein histidine kinase activity
KM403_23965	COG4191	Histidine kinase
KM403_23970	COG2267	carboxylic ester hydrolase activity
KM403_23990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM403_23995	COG1116	anion transmembrane transporter activity
KM403_24000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM403_24025	COG0494	nUDIX hydrolase
KM403_24055	COG0288	reversible hydration of carbon dioxide
KM403_24060	COG1271	oxidase subunit
KM403_24065	COG1294	oxidase, subunit
KM403_24085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_24110	COG1842	Phage shock protein A
KM403_24140	COG5002	protein histidine kinase activity
KM403_24145	COG0745	RESPONSE REGULATOR receiver
KM403_24175	COG1597	lipid kinase activity
KM403_24210	COG0586	Pfam SNARE associated Golgi protein
KM403_24220	COG0577	efflux transmembrane transporter activity
KM403_24225	COG1136	(ABC) transporter
KM403_24230	COG2207	Transcriptional regulator
KM403_24230	COG3708	Transcriptional regulator
KM403_24235	COG0745	RESPONSE REGULATOR receiver
KM403_24240	COG2205	protein histidine kinase activity
KM403_24245	COG0577	efflux transmembrane transporter activity
KM403_24255	COG0577	efflux transmembrane transporter activity
KM403_24260	COG1136	(ABC) transporter
KM403_24280	COG2188	Transcriptional regulator
KM403_24300	COG3964	amidohydrolase
KM403_24330	COG4948	Mandelate Racemase Muconate Lactonizing
KM403_24340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM403_24345	COG0596	Alpha beta hydrolase
KM403_24350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM403_24355	COG1169	isochorismate synthase
KM403_24360	COG1575	Belongs to the MenA family. Type 1 subfamily
KM403_24365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM403_24385	COG0058	SHG alpha-glucan phosphorylase activity
KM403_24390	COG0297	glycogen (starch) synthase activity
KM403_24395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM403_24515	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM403_24550	COG1285	pathogenesis
KM403_24555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM403_24565	COG0166	Belongs to the GPI family
KM403_24570	COG2155	Conserved Protein
KM403_24575	COG1098	S1 RNA binding domain
KM403_24580	COG0436	Aminotransferase
KM403_24585	COG1522	sequence-specific DNA binding
KM403_24590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM403_24595	COG2267	carboxylic ester hydrolase activity
KM403_24605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM403_24625	COG5018	Exonuclease
KM403_24630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM403_24650	COG2050	protein possibly involved in aromatic compounds catabolism
KM403_24660	COG1268	BioY protein
KM403_24670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM403_24675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM403_24690	COG3584	3D domain protein
KM403_24705	COG1252	NADH dehydrogenase
KM403_24720	COG3708	Transcriptional regulator
KM403_24735	COG1683	Conserved Protein
KM403_24755	COG0316	Belongs to the HesB IscA family
KM403_24770	COG1252	NADH dehydrogenase
KM403_24785	COG0390	transport system, permease component
KM403_24790	COG2824	Alkylphosphonate utilization operon protein PhnA
KM403_24830	COG4837	Protein of unknown function (DUF1462)
KM403_24835	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM403_24845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM403_24850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM403_24860	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM403_24865	COG0647	UMP catabolic process
KM403_24875	COG2445	Protein of unknown function DUF86
KM403_24880	COG1494	fructose-1,6-bisphosphatase
KM403_24895	COG4470	Protein conserved in bacteria
KM403_24905	COG0789	Transcriptional regulator
KM403_24910	COG4377	Putative membrane peptidase family (DUF2324)
KM403_24935	COG0739	heme binding
KM403_24945	COG3377	Domain of unknown function (DUF1805)
KM403_24950	COG0737	Belongs to the 5'-nucleotidase family
KM403_24955	COG1695	Transcriptional regulator
KM403_24965	COG0719	Fe-S assembly protein
KM403_24970	COG0822	iron-sulfur transferase activity
KM403_24975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM403_24980	COG0719	Fe-S assembly protein
KM403_24985	COG0396	ATPase activity
KM403_24990	COG1464	Belongs to the NlpA lipoprotein family
KM403_24995	COG1464	Belongs to the NlpA lipoprotein family
KM403_25000	COG2011	ABC-type metal ion transport system permease component
KM403_25005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM403_25015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM403_25020	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM403_25030	COG1393	Belongs to the ArsC family
KM403_25075	COG0039	L-malate dehydrogenase activity
KM403_25095	COG1309	transcriptional regulator
KM403_25100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM403_25105	COG1960	acyl-CoA dehydrogenase activity
KM403_25110	COG0183	Belongs to the thiolase family
KM403_25115	COG1024	Enoyl-CoA hydratase
KM403_25115	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM403_25125	COG1686	Belongs to the peptidase S11 family
KM403_25140	COG0011	TIGRFAM Protein of
KM403_25145	COG0840	transmembrane signaling receptor activity
KM403_25165	COG2814	Major facilitator Superfamily
KM403_25170	COG0531	amino acid
KM403_25180	COG0706	membrane insertase activity
KM403_25190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM403_25225	COG0586	Pfam SNARE associated Golgi protein
KM403_25235	COG1376	ErfK ybiS ycfS ynhG family protein
KM403_25240	COG0745	RESPONSE REGULATOR receiver
KM403_25245	COG5002	protein histidine kinase activity
KM403_25270	COG2151	metal-sulfur cluster biosynthetic enzyme
KM403_25275	COG3227	Zinc metalloprotease (Elastase)
KM403_25280	COG1741	Belongs to the pirin family
KM403_25295	COG0475	glutathione-regulated potassium exporter activity
KM403_25300	COG0490	domain, Protein
KM403_25305	COG1115	amino acid carrier protein
KM403_25310	COG0783	Belongs to the Dps family
KM403_25325	COG1611	Belongs to the LOG family
KM403_25345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_25350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_25355	COG1115	amino acid carrier protein
KM403_25360	COG1115	amino acid carrier protein
KM403_25365	COG2910	NAD(P)H-binding
KM403_25380	COG0656	L-ascorbic acid biosynthetic process
KM403_25385	COG2814	Major facilitator Superfamily
KM403_25390	COG1733	regulation of RNA biosynthetic process
KM403_25400	COG1252	NADH dehydrogenase
KM403_25405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM403_25410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM403_25420	COG0840	transmembrane signaling receptor activity
KM403_25420	COG3290	protein histidine kinase activity
KM403_25430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM403_25435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM403_25450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM403_25505	COG0557	exoribonuclease II activity
KM403_25510	COG1647	Serine aminopeptidase, S33
KM403_25515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM403_25520	COG1346	cytolysis
KM403_25615	COG4695	Portal protein
KM403_25640	COG4974	Belongs to the 'phage' integrase family
KM403_25650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM403_25655	COG0149	triose-phosphate isomerase activity
KM403_25665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM403_25680	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM403_25705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM403_25720	COG2323	membrane
KM403_25725	COG0740	serine-type endopeptidase activity
KM403_25730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM403_25740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM403_25750	COG1051	belongs to the nudix hydrolase family
KM403_25760	COG0492	ferredoxin-NADP+ reductase activity
KM403_25765	COG0457	Tetratricopeptide repeat
KM403_25770	COG0110	maltose O-acetyltransferase activity
KM403_25790	COG1950	PFAM Membrane protein of
KM403_25800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM403_25805	COG0556	nucleotide-excision repair
KM403_25825	COG0789	Transcriptional regulator
KM403_25850	COG2855	membrane
KM403_25855	COG0583	DNA-binding transcription factor activity
KM403_25865	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM403_25870	COG0488	(ABC) transporter
KM403_25880	COG1132	(ABC) transporter
KM403_25885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM403_25890	COG0793	Belongs to the peptidase S41A family
KM403_25890	COG3409	Peptidoglycan-binding domain 1 protein
KM403_25895	COG2177	Part of the ABC transporter FtsEX involved in
KM403_25900	COG2884	Cell division ATP-binding protein ftsE
KM403_25915	COG0653	protein targeting
KM403_25920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM403_25925	COG1278	Cold shock
KM403_25930	COG1040	competence protein
KM403_25935	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM403_25940	COG0791	NLP P60 protein
KM403_25940	COG1388	LysM domain
KM403_25945	COG1733	regulation of RNA biosynthetic process
KM403_25950	COG1307	EDD domain protein, DegV family
KM403_25955	COG1739	Uncharacterized protein family UPF0029
KM403_25960	COG1316	TRANSCRIPTIONal
KM403_25965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM403_25970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM403_25975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM403_25985	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM403_25985	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM403_26000	COG3394	polysaccharide catabolic process
KM403_26005	COG1486	melibiose metabolic process
KM403_26010	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM403_26015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM403_26025	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM403_26030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM403_26035	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM403_26045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM403_26050	COG1301	dicarboxylic acid transport
KM403_26060	COG0346	lactoylglutathione lyase activity
KM403_26065	COG1511	domain protein
KM403_26070	COG0583	DNA-binding transcription factor activity
KM403_26075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM403_26090	COG1271	oxidase subunit
KM403_26095	COG1294	oxidase, subunit
KM403_26100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM403_26110	COG1620	l-lactate permease
KM403_26120	COG2389	metal-binding protein
KM403_26130	COG1368	sulfuric ester hydrolase activity
KM403_26145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM403_26155	COG1215	transferase activity, transferring glycosyl groups
KM403_26160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM403_26165	COG3584	3D domain protein
KM403_26165	COG1388	LysM domain
KM403_26190	COG4715	Zinc finger, swim domain protein
KM403_26195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM403_26235	COG0577	efflux transmembrane transporter activity
KM403_26240	COG1136	(ABC) transporter
KM403_26275	COG5002	protein histidine kinase activity
KM403_26280	COG0745	RESPONSE REGULATOR receiver
KM403_26285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM403_26300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM403_26305	COG1134	teichoic acid transport
KM403_26310	COG1682	transport, permease protein
KM403_26315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM403_26360	COG1609	Transcriptional regulator
KM403_26375	COG0739	heme binding
KM403_26395	COG2385	sporulation resulting in formation of a cellular spore
KM403_26410	COG4836	Membrane
KM403_26415	COG1007	ATP synthesis coupled electron transport
KM403_26420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM403_26425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM403_26435	COG0839	Belongs to the complex I subunit 6 family
KM403_26450	COG0649	NAD binding
KM403_26455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM403_26470	COG5001	Diguanylate cyclase
KM403_26470	COG3300	MHYT domain
KM403_26520	COG0356	it plays a direct role in the translocation of protons across the membrane
KM403_26555	COG0698	ribose 5-phosphate isomerase
KM403_26565	COG2190	(PTS) system
KM403_26570	COG2259	Doxx family
KM403_26575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM403_26590	COG0009	L-threonylcarbamoyladenylate synthase
KM403_26605	COG2890	protein-(glutamine-N5) methyltransferase activity
KM403_26625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM403_26630	COG1494	fructose-1,6-bisphosphatase
KM403_26650	COG4821	SIS domain
KM403_26660	COG3343	RNA polymerase activity
KM403_26670	COG1960	acyl-CoA dehydrogenase activity
KM403_26675	COG1960	acyl-CoA dehydrogenase activity
KM403_26680	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM403_26685	COG0183	Belongs to the thiolase family
KM403_26690	COG0247	lactate metabolic process
KM403_26690	COG2181	nitrate reductase activity
KM403_26695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM403_26705	COG3300	MHYT domain
KM403_26705	COG5001	Diguanylate cyclase
KM403_26725	COG2197	response regulator
KM403_26730	COG4585	Histidine kinase
KM403_26735	COG0842	Transport permease protein
KM403_26740	COG1131	(ABC) transporter
KM403_26745	COG0024	Methionine aminopeptidase
KM403_26755	COG2234	aminopeptidase activity
KM403_26775	COG1595	DNA-templated transcription, initiation
KM403_26780	COG0018	arginyl-trna synthetase
KM403_26785	COG4506	Protein conserved in bacteria
KM403_26790	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM403_26805	COG0010	Belongs to the arginase family
KM403_26815	COG2814	Major facilitator Superfamily
KM403_26820	COG0789	Transcriptional regulator
KM403_26825	COG0584	glycerophosphoryl diester phosphodiesterase
KM403_26830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM403_26840	COG1994	Peptidase M50
KM403_26850	COG1078	dGTPase activity
KM403_26855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM403_26860	COG1120	ATPase activity
KM403_26865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM403_26890	COG0095	Lipoate-protein ligase
KM403_26895	COG0280	phosphate acetyltransferase
KM403_26910	COG3773	Cell wall hydrolase
KM403_26920	COG2363	Small membrane protein
KM403_26930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM403_26935	COG2233	PERMEase
KM403_26940	COG0561	phosphatase activity
KM403_26945	COG2814	Major facilitator Superfamily
KM403_26955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM403_26960	COG1131	(ABC) transporter
KM403_26965	COG2755	lipolytic protein G-D-S-L family
KM403_26970	COG1609	Transcriptional regulator
KM403_26980	COG0460	homoserine dehydrogenase
KM403_26990	COG2873	o-acetylhomoserine
KM403_27000	COG1011	Hydrolase
KM403_27005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM403_27015	COG2197	response regulator
KM403_27025	COG0351	phosphomethylpyrimidine kinase
KM403_27030	COG3706	GGDEF domain
KM403_27035	COG2879	small protein
KM403_27040	COG1966	Carbon starvation protein
KM403_27045	COG3279	Response regulator of the LytR AlgR family
KM403_27050	COG0477	Major facilitator Superfamily
KM403_27075	COG0840	transmembrane signaling receptor activity
KM403_27085	COG1607	acyl-coa hydrolase
KM403_27100	COG0488	(ABC) transporter
KM403_27120	COG0463	Glycosyl transferase, family 2
KM403_27125	COG1309	transcriptional regulator
KM403_27130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM403_27135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM403_27135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM403_27140	COG0628	permease
KM403_27155	COG3279	Response regulator of the LytR AlgR family
KM403_27160	COG3275	phosphorelay sensor kinase activity
KM403_27165	COG2814	Major facilitator Superfamily
KM403_27170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM403_27175	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM403_27180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM403_27200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM403_27205	COG1272	protein, Hemolysin III
KM403_27225	COG0516	GMP reductase activity
KM403_27230	COG1164	Oligoendopeptidase f
KM403_27250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM403_27255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM403_27260	COG4853	Protein conserved in bacteria
KM403_27265	COG4863	YycH protein
KM403_27270	COG5002	protein histidine kinase activity
KM403_27275	COG0745	RESPONSE REGULATOR receiver
KM403_27305	COG0305	Participates in initiation and elongation during chromosome replication
KM403_27315	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM403_27320	COG4241	membrane
KM403_27330	COG0629	single-stranded DNA binding
KM403_27340	COG0012	GTP binding
KM403_27345	COG4481	Protein conserved in bacteria
KM403_27350	COG0668	transmembrane transport
KM403_27360	COG1475	DNA binding
KM403_27365	COG1192	Involved in chromosome partitioning
KM403_27390	COG1847	R3H domain protein
KM403_27395	COG0706	membrane insertase activity
KM403_27405	COG0230	Belongs to the bacterial ribosomal protein bL34 family