locus-tag	class	description
KM404_00010	COG0592	DNA-directed DNA polymerase activity
KM404_00015	COG2501	S4 domain
KM404_00025	COG0187	DNA topoisomerase II activity
KM404_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM404_00065	COG0516	GMP reductase activity
KM404_00065	COG0517	IMP dehydrogenase activity
KM404_00070	COG1686	Belongs to the peptidase S11 family
KM404_00100	COG1428	Deoxynucleoside kinase
KM404_00105	COG1428	Deoxynucleoside kinase
KM404_00110	COG1335	isochorismatase
KM404_00115	COG0590	tRNA wobble adenosine to inosine editing
KM404_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM404_00180	COG1982	Orn Lys Arg decarboxylase major
KM404_00190	COG0470	DNA polymerase III
KM404_00195	COG1774	PSP1 C-terminal conserved region
KM404_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM404_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM404_00220	COG2002	toxin-antitoxin pair type II binding
KM404_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM404_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM404_00230	COG0084	hydrolase, TatD family'
KM404_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM404_00250	COG4466	Protein conserved in bacteria
KM404_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM404_00270	COG0251	oxidation-reduction process
KM404_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM404_00305	COG2002	toxin-antitoxin pair type II binding
KM404_00310	COG2244	polysaccharide biosynthetic process
KM404_00315	COG3956	TIGRFAM MazG family protein
KM404_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM404_00340	COG1098	S1 RNA binding domain
KM404_00355	COG2208	phosphoserine phosphatase activity
KM404_00360	COG0037	tRNA processing
KM404_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM404_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM404_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM404_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM404_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM404_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM404_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM404_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM404_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM404_00420	COG1396	sequence-specific DNA binding
KM404_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM404_00455	COG3880	PFAM UvrB UvrC protein
KM404_00465	COG0542	response to heat
KM404_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM404_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM404_00500	COG1045	serine acetyltransferase
KM404_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM404_00520	COG3688	RNA-binding protein containing a PIN domain
KM404_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM404_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM404_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM404_00565	COG2813	Specifically methylates the guanine in position
KM404_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM404_00580	COG1358	cellular component organization or biogenesis
KM404_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM404_00710	COG0201	protein transport
KM404_00720	COG0024	Methionine aminopeptidase
KM404_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM404_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM404_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM404_00795	COG0489	protein tyrosine kinase activity
KM404_00805	COG2194	sulfuric ester hydrolase activity
KM404_00810	COG0726	polysaccharide deacetylase
KM404_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM404_00895	COG4856	YbbR-like protein
KM404_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM404_00915	COG0596	Alpha beta hydrolase
KM404_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM404_00940	COG4946	Tricorn protease homolog
KM404_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM404_00940	COG1506	peptidase
KM404_00975	COG2011	ABC-type metal ion transport system permease component
KM404_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM404_00985	COG1464	Belongs to the NlpA lipoprotein family
KM404_00990	COG0604	alcohol dehydrogenase
KM404_01000	COG0277	FAD linked oxidase domain protein
KM404_01005	COG2271	Major facilitator Superfamily
KM404_01015	COG2814	Major facilitator Superfamily
KM404_01030	COG0601	transmembrane transport
KM404_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM404_01040	COG0444	Belongs to the ABC transporter superfamily
KM404_01045	COG4608	Belongs to the ABC transporter superfamily
KM404_01050	COG4166	transmembrane transport
KM404_01060	COG2207	Transcriptional regulator
KM404_01075	COG4166	transmembrane transport
KM404_01080	COG4166	transmembrane transport
KM404_01085	COG0656	L-ascorbic acid biosynthetic process
KM404_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM404_01105	COG4149	molybdate abc transporter
KM404_01115	COG1910	domain protein
KM404_01125	COG0583	DNA-binding transcription factor activity
KM404_01130	COG0697	spore germination
KM404_01145	COG0204	Acyl-transferase
KM404_01155	COG1609	Transcriptional regulator
KM404_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_01175	COG0084	hydrolase, TatD family'
KM404_01180	COG5298	Protein conserved in bacteria
KM404_01205	COG0488	(ABC) transporter
KM404_01220	COG0747	negative chemotaxis
KM404_01225	COG0601	transmembrane transport
KM404_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM404_01235	COG0444	Belongs to the ABC transporter superfamily
KM404_01240	COG4608	Belongs to the ABC transporter superfamily
KM404_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM404_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM404_01290	COG2814	Major facilitator Superfamily
KM404_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM404_01310	COG4294	response to UV
KM404_01315	COG0457	Tetratricopeptide repeat
KM404_01315	COG0705	Rhomboid family
KM404_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM404_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM404_01335	COG0864	Transcriptional regulator
KM404_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM404_01345	COG2183	response to ionizing radiation
KM404_01440	COG0802	atpase or kinase
KM404_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM404_01450	COG0456	acetyltransferase
KM404_01460	COG0488	(ABC) transporter
KM404_01475	COG1266	CAAX protease self-immunity
KM404_01495	COG2252	PERMEase
KM404_01505	COG5002	protein histidine kinase activity
KM404_01535	COG2226	methyltransferase
KM404_01575	COG1968	undecaprenyl-diphosphatase activity
KM404_01590	COG2205	protein histidine kinase activity
KM404_01595	COG0745	RESPONSE REGULATOR receiver
KM404_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM404_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM404_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM404_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM404_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM404_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM404_01670	COG0151	Belongs to the GarS family
KM404_01695	COG0210	DNA helicase
KM404_01705	COG4851	CamS sex pheromone cAM373 precursor
KM404_01725	COG1335	isochorismatase
KM404_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM404_01735	COG2011	ABC-type metal ion transport system permease component
KM404_01740	COG1464	Belongs to the NlpA lipoprotein family
KM404_01760	COG1846	Transcriptional regulator
KM404_01785	COG1597	lipid kinase activity
KM404_01790	COG0546	phosphoglycolate phosphatase activity
KM404_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM404_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM404_01810	COG2076	Multidrug Resistance protein
KM404_01815	COG2309	aminopeptidase activity
KM404_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM404_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM404_01850	COG4807	Protein conserved in bacteria
KM404_01875	COG1757	Na H antiporter
KM404_01880	COG1473	amidohydrolase
KM404_01895	COG0450	alkyl hydroperoxide reductase
KM404_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_01940	COG0166	Belongs to the GPI family
KM404_01975	COG5002	protein histidine kinase activity
KM404_01995	COG3541	Predicted nucleotidyltransferase
KM404_02000	COG2814	Major facilitator Superfamily
KM404_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM404_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM404_02015	COG0765	amino acid transport
KM404_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM404_02030	COG0840	transmembrane signaling receptor activity
KM404_02035	COG0840	transmembrane signaling receptor activity
KM404_02040	COG0366	Alpha amylase catalytic
KM404_02045	COG2190	(PTS) system
KM404_02045	COG1263	PTS System
KM404_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM404_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM404_02100	COG1116	anion transmembrane transporter activity
KM404_02105	COG0488	(ABC) transporter
KM404_02150	COG2270	Major facilitator Superfamily
KM404_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM404_02180	COG2310	stress, protein
KM404_02185	COG2310	stress, protein
KM404_02190	COG2310	stress, protein
KM404_02195	COG0861	Integral membrane protein TerC family
KM404_02205	COG3853	Toxic anion resistance protein (TelA)
KM404_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM404_02230	COG1295	ribonuclease BN
KM404_02235	COG2217	Heavy metal translocating P-type atpase
KM404_02240	COG0697	spore germination
KM404_02260	COG0586	Pfam SNARE associated Golgi protein
KM404_02275	COG3871	stress protein (general stress protein 26)
KM404_02280	COG0387	Pfam Sodium calcium exchanger
KM404_02290	COG0535	radical SAM domain protein
KM404_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM404_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM404_02325	COG0582	viral genome integration into host DNA
KM404_02335	COG1396	sequence-specific DNA binding
KM404_02350	COG1396	sequence-specific DNA binding
KM404_02385	COG1484	DNA-dependent DNA replication
KM404_02615	COG0101	tRNA pseudouridine synthase activity
KM404_02625	COG3829	transcription factor binding
KM404_02635	COG0833	amino acid
KM404_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM404_02670	COG1263	PTS System
KM404_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM404_02690	COG0463	Glycosyl transferase, family 2
KM404_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM404_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM404_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM404_02745	COG1228	amidohydrolase
KM404_02750	COG1090	epimerase
KM404_02780	COG1988	membrane-bound metal-dependent
KM404_02785	COG1194	a g-specific adenine glycosylase
KM404_02810	COG1132	(ABC) transporter
KM404_02815	COG4129	membrane
KM404_02820	COG0070	glutamate synthase
KM404_02820	COG0069	glutamate synthase activity
KM404_02820	COG0067	glutamate synthase
KM404_02830	COG4555	ABC transporter
KM404_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM404_02855	COG0735	belongs to the Fur family
KM404_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM404_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM404_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM404_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM404_03005	COG2766	serine protein kinase
KM404_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM404_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM404_03040	COG2268	Band 7 protein
KM404_03050	COG3290	protein histidine kinase activity
KM404_03055	COG4565	transcriptional regulatory protein
KM404_03060	COG2851	Citrate transporter
KM404_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM404_03085	COG3842	ATPase activity
KM404_03090	COG1175	transmembrane transport
KM404_03095	COG0395	ABC-type sugar transport system, permease component
KM404_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM404_03110	COG0745	RESPONSE REGULATOR receiver
KM404_03115	COG5002	protein histidine kinase activity
KM404_03125	COG4990	cell redox homeostasis
KM404_03135	COG3290	protein histidine kinase activity
KM404_03140	COG4565	transcriptional regulatory protein
KM404_03145	COG3493	citrate carrier protein
KM404_03150	COG0281	malic enzyme
KM404_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_03175	COG5002	protein histidine kinase activity
KM404_03180	COG0745	RESPONSE REGULATOR receiver
KM404_03185	COG0454	-acetyltransferase
KM404_03185	COG0456	acetyltransferase
KM404_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM404_03195	COG3383	formate dehydrogenase (NAD+) activity
KM404_03200	COG2427	Protein of unknown function (DUF1641)
KM404_03215	COG0531	amino acid
KM404_03220	COG0640	Transcriptional regulator
KM404_03225	COG2217	Heavy metal translocating P-type atpase
KM404_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM404_03245	COG3227	Zinc metalloprotease (Elastase)
KM404_03265	COG2720	vancomycin resistance protein
KM404_03270	COG1316	TRANSCRIPTIONal
KM404_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_03280	COG0346	lactoylglutathione lyase activity
KM404_03285	COG1253	flavin adenine dinucleotide binding
KM404_03290	COG1027	Aspartate ammonia-lyase
KM404_03295	COG1620	l-lactate permease
KM404_03310	COG3104	oligopeptide transport
KM404_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_03335	COG2226	methyltransferase
KM404_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM404_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM404_03355	COG4548	von Willebrand factor, type A
KM404_03360	COG0714	Associated with various cellular activities
KM404_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM404_03385	COG0531	amino acid
KM404_03390	COG2188	Transcriptional regulator
KM404_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_03395	COG1263	PTS System
KM404_03400	COG0366	Alpha amylase catalytic
KM404_03415	COG0697	spore germination
KM404_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM404_03430	COG1115	amino acid carrier protein
KM404_03435	COG1126	abc transporter atp-binding protein
KM404_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM404_03445	COG0765	amino acid transport
KM404_03450	COG0765	amino acid transport
KM404_03455	COG0833	amino acid
KM404_03480	COG2378	regulation of single-species biofilm formation
KM404_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM404_03490	COG5002	protein histidine kinase activity
KM404_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM404_03520	COG0747	negative chemotaxis
KM404_03530	COG0601	transmembrane transport
KM404_03535	COG4608	Belongs to the ABC transporter superfamily
KM404_03545	COG2271	Major facilitator Superfamily
KM404_03550	COG1846	Transcriptional regulator
KM404_03560	COG1609	Transcriptional regulator
KM404_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM404_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM404_03585	COG1879	ABC-type sugar transport system periplasmic component
KM404_03610	COG1063	alcohol dehydrogenase
KM404_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM404_03650	COG1968	undecaprenyl-diphosphatase activity
KM404_03655	COG0840	transmembrane signaling receptor activity
KM404_03660	COG3584	3D domain protein
KM404_03660	COG1388	LysM domain
KM404_03665	COG1476	TRANSCRIPTIONal
KM404_03680	COG3104	oligopeptide transport
KM404_03685	COG1114	Component of the transport system for branched-chain amino acids
KM404_03700	COG1113	amino acid transport
KM404_03705	COG2252	PERMEase
KM404_03730	COG0569	domain protein
KM404_03730	COG0475	glutathione-regulated potassium exporter activity
KM404_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM404_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM404_03755	COG0833	amino acid
KM404_03760	COG4990	cell redox homeostasis
KM404_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM404_03780	COG0697	spore germination
KM404_03785	COG0531	amino acid
KM404_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM404_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM404_03805	COG1918	ferrous iron import across plasma membrane
KM404_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM404_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM404_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM404_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM404_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM404_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM404_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM404_03975	COG1116	anion transmembrane transporter activity
KM404_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM404_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM404_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM404_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM404_04000	COG2104	thiamine diphosphate biosynthetic process
KM404_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM404_04015	COG0351	phosphomethylpyrimidine kinase
KM404_04055	COG2205	protein histidine kinase activity
KM404_04060	COG2814	Major facilitator Superfamily
KM404_04065	COG1846	Transcriptional regulator
KM404_04080	COG2252	PERMEase
KM404_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM404_04105	COG1621	beta-fructofuranosidase activity
KM404_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_04110	COG1263	PTS System
KM404_04115	COG1609	Transcriptional regulator
KM404_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM404_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM404_04165	COG0778	Nitroreductase
KM404_04170	COG2719	SpoVR family
KM404_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM404_04200	COG1937	Protein conserved in bacteria
KM404_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM404_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM404_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM404_04235	COG0730	response to heat
KM404_04245	COG1316	TRANSCRIPTIONal
KM404_04250	COG0604	alcohol dehydrogenase
KM404_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM404_04270	COG3711	transcriptional antiterminator
KM404_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM404_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM404_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM404_04300	COG1388	LysM domain
KM404_04300	COG3584	3D domain protein
KM404_04305	COG0577	efflux transmembrane transporter activity
KM404_04310	COG1136	(ABC) transporter
KM404_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM404_04335	COG1114	Component of the transport system for branched-chain amino acids
KM404_04340	COG3546	catalase activity
KM404_04375	COG0586	Pfam SNARE associated Golgi protein
KM404_04410	COG0531	amino acid
KM404_04415	COG0475	glutathione-regulated potassium exporter activity
KM404_04425	COG1737	Transcriptional regulator
KM404_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_04435	COG1263	PTS System
KM404_04445	COG2259	Doxx family
KM404_04460	COG0697	spore germination
KM404_04465	COG1522	sequence-specific DNA binding
KM404_04480	COG2076	Multidrug Resistance protein
KM404_04485	COG1309	transcriptional regulator
KM404_04490	COG2814	Major facilitator Superfamily
KM404_04495	COG1733	regulation of RNA biosynthetic process
KM404_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM404_04510	COG4533	DNA binding
KM404_04515	COG2211	Major facilitator Superfamily
KM404_04525	COG0693	protein deglycase activity
KM404_04530	COG0693	protein deglycase activity
KM404_04530	COG0753	catalase activity
KM404_04540	COG0531	amino acid
KM404_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM404_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM404_04560	COG1132	(ABC) transporter
KM404_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM404_04575	COG0765	amino acid transport
KM404_04580	COG1126	abc transporter atp-binding protein
KM404_04595	COG0189	ligase activity
KM404_04625	COG0028	Belongs to the TPP enzyme family
KM404_04630	COG3527	Alpha-acetolactate decarboxylase
KM404_04645	COG0561	phosphatase activity
KM404_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM404_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM404_04695	COG0653	protein targeting
KM404_04700	COG2244	polysaccharide biosynthetic process
KM404_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM404_04715	COG4196	transglutaminase domain protein
KM404_04730	COG1696	Membrane protein involved in D-alanine export
KM404_04745	COG1024	Enoyl-CoA hydratase
KM404_04765	COG1363	Peptidase, m42
KM404_04785	COG3938	Belongs to the proline racemase family
KM404_04825	COG0601	transmembrane transport
KM404_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM404_04840	COG4608	Belongs to the ABC transporter superfamily
KM404_04845	COG0322	excinuclease ABC activity
KM404_04875	COG0477	Major facilitator Superfamily
KM404_04880	COG3290	protein histidine kinase activity
KM404_04885	COG4565	transcriptional regulatory protein
KM404_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM404_04920	COG0789	Transcriptional regulator
KM404_04920	COG4978	Transcriptional regulator
KM404_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM404_04975	COG0477	Major facilitator Superfamily
KM404_05020	COG3320	Male sterility
KM404_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM404_05025	COG1309	transcriptional regulator
KM404_05045	COG1183	phosphatidylcholine synthase activity
KM404_05065	COG2376	Dihydroxyacetone kinase
KM404_05075	COG2376	Dihydroxyacetone kinase
KM404_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM404_05085	COG1959	2 iron, 2 sulfur cluster binding
KM404_05115	COG2770	Histidine kinase
KM404_05115	COG3437	response regulator, receiver
KM404_05165	COG3237	CsbD-like
KM404_05190	COG1191	sigma factor activity
KM404_05200	COG2208	phosphoserine phosphatase activity
KM404_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM404_05210	COG2205	protein histidine kinase activity
KM404_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM404_05210	COG2198	Histidine kinase
KM404_05210	COG0784	Response regulator, receiver
KM404_05265	COG0420	3'-5' exonuclease activity
KM404_05270	COG4717	serine-type aminopeptidase activity
KM404_05290	COG1309	transcriptional regulator
KM404_05295	COG2814	Major facilitator Superfamily
KM404_05300	COG0346	lactoylglutathione lyase activity
KM404_05310	COG0346	lactoylglutathione lyase activity
KM404_05315	COG0457	Tetratricopeptide repeat
KM404_05320	COG2267	carboxylic ester hydrolase activity
KM404_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM404_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM404_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM404_05395	COG0477	Major facilitator Superfamily
KM404_05400	COG0477	Major facilitator Superfamily
KM404_05410	COG3973	AAA domain
KM404_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM404_05435	COG4980	gas vesicle protein
KM404_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM404_05445	COG1131	(ABC) transporter
KM404_05450	COG4473	ABC transporter
KM404_05465	COG1309	transcriptional regulator
KM404_05475	COG3402	PFAM membrane-flanked domain
KM404_05525	COG3402	PFAM membrane-flanked domain
KM404_05530	COG3428	Bacterial PH domain
KM404_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM404_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM404_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM404_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM404_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM404_05590	COG1309	transcriptional regulator
KM404_05595	COG1511	domain protein
KM404_05620	COG1609	Transcriptional regulator
KM404_05630	COG1234	tRNA 3'-trailer cleavage
KM404_05635	COG0095	Lipoate-protein ligase
KM404_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_05675	COG3209	COG3209 Rhs family protein
KM404_05715	COG1078	dGTPase activity
KM404_05725	COG1595	DNA-templated transcription, initiation
KM404_05730	COG2207	Transcriptional regulator
KM404_05730	COG3708	Transcriptional regulator
KM404_05745	COG2205	protein histidine kinase activity
KM404_05750	COG0745	RESPONSE REGULATOR receiver
KM404_05780	COG0501	Belongs to the peptidase M48B family
KM404_05785	COG0840	transmembrane signaling receptor activity
KM404_05790	COG0697	spore germination
KM404_05810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM404_05815	COG2224	Isocitrate lyase
KM404_05840	COG4903	ComK protein
KM404_05845	COG0398	Pfam SNARE associated Golgi protein
KM404_05855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM404_05860	COG1074	ATP-dependent DNA helicase activity
KM404_05905	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM404_05930	COG0367	asparagine synthase
KM404_05935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM404_05940	COG0753	catalase activity
KM404_05945	COG0004	ammonium transporteR
KM404_05965	COG2996	Protein conserved in bacteria
KM404_05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM404_05985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_06000	COG0561	phosphatase activity
KM404_06010	COG0542	response to heat
KM404_06020	COG2267	carboxylic ester hydrolase activity
KM404_06035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM404_06045	COG5504	Zn-dependent protease
KM404_06055	COG0180	Tryptophanyl-tRNA synthetase
KM404_06065	COG4166	transmembrane transport
KM404_06070	COG0601	transmembrane transport
KM404_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM404_06080	COG0444	Belongs to the ABC transporter superfamily
KM404_06085	COG4608	Belongs to the ABC transporter superfamily
KM404_06090	COG0534	Mate efflux family protein
KM404_06095	COG4166	transmembrane transport
KM404_06110	COG0861	Integral membrane protein TerC family
KM404_06115	COG4862	establishment of competence for transformation
KM404_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM404_06130	COG1164	Oligoendopeptidase f
KM404_06140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM404_06145	COG2346	COG2346, Truncated hemoglobins
KM404_06150	COG4116	CYTH
KM404_06160	COG2357	RelA SpoT domain protein
KM404_06170	COG0564	pseudouridine synthase activity
KM404_06190	COG0463	Glycosyl transferase, family 2
KM404_06190	COG1216	Glycosyl transferase, family 2
KM404_06210	COG0457	Tetratricopeptide repeat
KM404_06210	COG0463	Glycosyl transferase, family 2
KM404_06230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM404_06245	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM404_06290	COG2153	protein acetylation
KM404_06300	COG2382	esterase
KM404_06315	COG5492	domain, Protein
KM404_06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM404_06330	COG0512	Glutamine amidotransferase of anthranilate synthase
KM404_06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM404_06365	COG1620	l-lactate permease
KM404_06370	COG5634	Uncharacterized conserved protein (DUF2278)
KM404_06425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM404_06435	COG1476	TRANSCRIPTIONal
KM404_06495	COG2226	methyltransferase
KM404_06505	COG1686	Belongs to the peptidase S11 family
KM404_06510	COG0681	Belongs to the peptidase S26 family
KM404_06545	COG1012	belongs to the aldehyde dehydrogenase family
KM404_06550	COG3842	ATPase activity
KM404_06555	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM404_06560	COG1177	transmembrane transport
KM404_06565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM404_06575	COG2409	Drug exporters of the RND superfamily
KM404_06585	COG0564	pseudouridine synthase activity
KM404_06595	COG2340	Cysteine-rich secretory protein family
KM404_06600	COG0247	lactate metabolic process
KM404_06605	COG0277	FAD linked oxidase domain protein
KM404_06610	COG3835	regulator
KM404_06620	COG0745	RESPONSE REGULATOR receiver
KM404_06625	COG5002	protein histidine kinase activity
KM404_06630	COG2186	Transcriptional regulator
KM404_06650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM404_06665	COG2116	formate transmembrane transporter activity
KM404_06670	COG0861	Integral membrane protein TerC family
KM404_06675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM404_06685	COG2030	dehydratase
KM404_06705	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_06710	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM404_06715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM404_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM404_06735	COG1840	ABC-type Fe3 transport system, periplasmic component
KM404_06765	COG1349	DNA-binding transcription factor activity
KM404_06785	COG2861	carbohydrate metabolic process
KM404_06795	COG3852	Histidine kinase
KM404_06800	COG1846	Transcriptional regulator
KM404_06810	COG2318	DinB family
KM404_06815	COG5002	protein histidine kinase activity
KM404_06825	COG0720	synthase
KM404_06840	COG4873	Protein conserved in bacteria
KM404_06870	COG1780	Probably involved in ribonucleotide reductase function
KM404_06890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM404_06895	COG1725	Transcriptional regulator
KM404_06900	COG1131	(ABC) transporter
KM404_06910	COG1131	(ABC) transporter
KM404_06915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM404_06930	COG1522	sequence-specific DNA binding
KM404_06940	COG1335	isochorismatase
KM404_06950	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM404_06955	COG2070	2-Nitropropane dioxygenase
KM404_06960	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM404_06970	COG1696	Membrane protein involved in D-alanine export
KM404_06995	COG0716	FMN binding
KM404_07010	COG3173	Aminoglycoside phosphotransferase
KM404_07030	COG0534	Mate efflux family protein
KM404_07035	COG1968	undecaprenyl-diphosphatase activity
KM404_07050	COG1846	Transcriptional regulator
KM404_07060	COG1301	dicarboxylic acid transport
KM404_07065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM404_07070	COG4709	membrane
KM404_07075	COG3874	Sporulation protein YtfJ
KM404_07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM404_07105	COG0028	Belongs to the TPP enzyme family
KM404_07110	COG0440	acetolactate synthase activity
KM404_07115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM404_07125	COG0473	3-isopropylmalate dehydrogenase activity
KM404_07150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM404_07185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM404_07200	COG1183	phosphatidylcholine synthase activity
KM404_07205	COG1368	sulfuric ester hydrolase activity
KM404_07215	COG0019	diaminopimelate decarboxylase activity
KM404_07235	COG0529	Catalyzes the synthesis of activated sulfate
KM404_07240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM404_07260	COG1648	precorrin-2 dehydrogenase activity
KM404_07265	COG0733	neurotransmitter:sodium symporter activity
KM404_07285	COG1757	Na H antiporter
KM404_07300	COG4758	membrane
KM404_07305	COG4585	Histidine kinase
KM404_07310	COG2197	response regulator
KM404_07320	COG1114	Component of the transport system for branched-chain amino acids
KM404_07330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM404_07355	COG1017	nitric oxide dioxygenase activity
KM404_07355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM404_07370	COG0730	response to heat
KM404_07375	COG0306	phosphate transporter
KM404_07380	COG1392	Phosphate transport regulator
KM404_07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM404_07400	COG3852	Histidine kinase
KM404_07405	COG1801	Protein of unknown function DUF72
KM404_07415	COG0582	viral genome integration into host DNA
KM404_07420	COG5002	protein histidine kinase activity
KM404_07440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM404_07440	COG0392	lysyltransferase activity
KM404_07455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM404_07460	COG1686	Belongs to the peptidase S11 family
KM404_07465	COG2715	membrane protein required for spore maturation
KM404_07470	COG0700	Nucleoside recognition
KM404_07475	COG1187	pseudouridine synthase activity
KM404_07485	COG1333	cytochrome c biogenesis protein
KM404_07490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM404_07495	COG0745	RESPONSE REGULATOR receiver
KM404_07500	COG5002	protein histidine kinase activity
KM404_07505	COG2096	Adenosyltransferase
KM404_07520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM404_07525	COG1141	Ferredoxin
KM404_07530	COG4955	Helix-turn-helix domain
KM404_07535	COG0514	ATP-dependent DNA helicase (RecQ)
KM404_07540	COG1266	CAAX protease self-immunity
KM404_07560	COG4862	establishment of competence for transformation
KM404_07565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM404_07585	COG0492	ferredoxin-NADP+ reductase activity
KM404_07660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM404_07675	COG0142	geranyltranstransferase activity
KM404_07685	COG0142	geranyltranstransferase activity
KM404_07705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM404_07710	COG0457	Tetratricopeptide repeat
KM404_07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM404_07740	COG4347	Protein of unknown function (DUF1405)
KM404_07755	COG2738	Putative neutral zinc metallopeptidase
KM404_07765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_07770	COG1694	Mazg nucleotide pyrophosphohydrolase
KM404_07785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM404_07790	COG0438	transferase activity, transferring glycosyl groups
KM404_07845	COG3935	DnaD domain protein
KM404_07850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM404_07860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM404_07860	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM404_07925	COG0116	Belongs to the methyltransferase superfamily
KM404_07935	COG1199	ATP-dependent helicase activity
KM404_07940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM404_07950	COG3173	Aminoglycoside phosphotransferase
KM404_07955	COG0024	Methionine aminopeptidase
KM404_07965	COG2233	PERMEase
KM404_07970	COG2311	Membrane
KM404_07975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM404_07985	COG0456	acetyltransferase
KM404_08035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM404_08060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM404_08075	COG1215	transferase activity, transferring glycosyl groups
KM404_08080	COG0438	transferase activity, transferring glycosyl groups
KM404_08095	COG0454	-acetyltransferase
KM404_08115	COG0328	RNA-DNA hybrid ribonuclease activity
KM404_08155	COG1280	lysine exporter protein (LysE YggA)
KM404_08170	COG3162	membrane
KM404_08175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM404_08180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM404_08190	COG0475	glutathione-regulated potassium exporter activity
KM404_08195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM404_08200	COG0789	Transcriptional regulator
KM404_08200	COG4978	Transcriptional regulator
KM404_08210	COG2323	membrane
KM404_08215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM404_08270	COG1923	regulation of RNA biosynthetic process
KM404_08280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM404_08285	COG1360	Flagellar Motor Protein
KM404_08290	COG2201	protein-glutamate methylesterase activity
KM404_08295	COG0643	Histidine kinase
KM404_08295	COG2198	Histidine kinase
KM404_08300	COG0643	Histidine kinase
KM404_08300	COG2198	Histidine kinase
KM404_08305	COG1776	CheC inhibitor of MCP methylation
KM404_08305	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM404_08320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM404_08340	COG1256	bacterial-type flagellum assembly
KM404_08365	COG1815	bacterial-type flagellum-dependent cell motility
KM404_08370	COG1558	bacterial-type flagellum-dependent cell motility
KM404_08385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM404_08395	COG1157	protein secretion by the type III secretion system
KM404_08435	COG0835	chemotaxis
KM404_08435	COG0784	Response regulator, receiver
KM404_08445	COG0463	Glycosyl transferase, family 2
KM404_08480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM404_08485	COG0741	lytic transglycosylase activity
KM404_08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM404_08500	COG1776	CheC inhibitor of MCP methylation
KM404_08510	COG1338	Plays a role in the flagellum-specific transport system
KM404_08515	COG1987	bacterial-type flagellum assembly
KM404_08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM404_08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM404_08535	COG1419	protein localization to endoplasmic reticulum
KM404_08540	COG4786	Flagellar basal body rod
KM404_08545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM404_08570	COG1309	transcriptional regulator
KM404_08590	COG2329	Antibiotic biosynthesis monooxygenase
KM404_08615	COG0583	DNA-binding transcription factor activity
KM404_08620	COG3842	ATPase activity
KM404_08625	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM404_08635	COG1234	tRNA 3'-trailer cleavage
KM404_08660	COG1686	Belongs to the peptidase S11 family
KM404_08670	COG0406	alpha-ribazole phosphatase activity
KM404_08700	COG0367	asparagine synthase
KM404_08730	COG1802	Transcriptional regulator
KM404_08735	COG0697	spore germination
KM404_08740	COG0523	cobalamin synthesis protein
KM404_08745	COG0701	Predicted permease
KM404_08755	COG0438	transferase activity, transferring glycosyl groups
KM404_08755	COG1216	Glycosyl transferase, family 2
KM404_08760	COG1757	Na H antiporter
KM404_08765	COG0114	fumarate hydratase activity
KM404_08790	COG3340	Belongs to the peptidase S51 family
KM404_08810	COG0785	Cytochrome C biogenesis protein
KM404_08840	COG2733	membrane
KM404_08875	COG1131	(ABC) transporter
KM404_08890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM404_08895	COG0528	UMP kinase activity
KM404_08905	COG1027	Aspartate ammonia-lyase
KM404_08910	COG0281	malic enzyme
KM404_08915	COG4191	Histidine kinase
KM404_08920	COG0784	Response regulator, receiver
KM404_08925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM404_08980	COG1051	belongs to the nudix hydrolase family
KM404_08985	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM404_08995	COG2814	Major facilitator Superfamily
KM404_09010	COG1966	Carbon starvation protein
KM404_09025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_09035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM404_09045	COG2223	nitrite transmembrane transporter activity
KM404_09050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM404_09065	COG2244	polysaccharide biosynthetic process
KM404_09070	COG0733	neurotransmitter:sodium symporter activity
KM404_09080	COG5566	PFAM Mor transcription activator
KM404_09085	COG2323	membrane
KM404_09100	COG2084	Dehydrogenase
KM404_09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM404_09125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM404_09130	COG0028	Belongs to the TPP enzyme family
KM404_09135	COG0440	acetolactate synthase activity
KM404_09140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM404_09150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM404_09175	COG2814	Major facilitator Superfamily
KM404_09180	COG3384	dioxygenase
KM404_09190	COG3279	Response regulator of the LytR AlgR family
KM404_09195	COG0427	acetyl-CoA hydrolase
KM404_09215	COG1073	alpha beta
KM404_09245	COG0535	radical SAM domain protein
KM404_09250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_09270	COG1914	H( )-stimulated, divalent metal cation uptake system
KM404_09285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM404_09315	COG2390	Transcriptional regulator
KM404_09325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_09330	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM404_09345	COG4224	UPF0291 protein
KM404_09365	COG0006	proline dipeptidase activity
KM404_09370	COG2132	Multicopper oxidase
KM404_09385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM404_09400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM404_09415	COG2372	response to copper ion
KM404_09415	COG1276	copper resistance
KM404_09420	COG4549	nuclear export factor GLE1
KM404_09430	COG0697	spore germination
KM404_09435	COG0583	DNA-binding transcription factor activity
KM404_09440	COG1959	2 iron, 2 sulfur cluster binding
KM404_09445	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM404_09450	COG0778	Nitroreductase
KM404_09460	COG0628	permease
KM404_09470	COG1231	oxidoreductase activity
KM404_09475	COG0523	cobalamin synthesis protein
KM404_09490	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_09495	COG2030	dehydratase
KM404_09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_09510	COG0411	ABC transporter
KM404_09530	COG0583	DNA-binding transcription factor activity
KM404_09540	COG1942	4-Oxalocrotonate Tautomerase
KM404_09550	COG1846	Transcriptional regulator
KM404_09560	COG1271	oxidase subunit
KM404_09565	COG1294	oxidase, subunit
KM404_09570	COG4988	ABC transporter
KM404_09575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM404_09595	COG1686	Belongs to the peptidase S11 family
KM404_09610	COG0791	NLP P60 protein
KM404_09610	COG1388	LysM domain
KM404_09625	COG0745	RESPONSE REGULATOR receiver
KM404_09630	COG5002	protein histidine kinase activity
KM404_09640	COG0300	oxidoreductase activity
KM404_09675	COG0460	homoserine dehydrogenase
KM404_09700	COG1316	TRANSCRIPTIONal
KM404_09710	COG0745	RESPONSE REGULATOR receiver
KM404_09715	COG5002	protein histidine kinase activity
KM404_09730	COG1285	pathogenesis
KM404_09735	COG1247	-acetyltransferase
KM404_09755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM404_09765	COG1082	Xylose isomerase domain protein TIM barrel
KM404_09780	COG1279	arginine transmembrane transporter activity
KM404_09790	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM404_09830	COG2002	toxin-antitoxin pair type II binding
KM404_09835	COG1404	Belongs to the peptidase S8 family
KM404_09840	COG0640	Transcriptional regulator
KM404_09845	COG0667	Aldo Keto reductase
KM404_09850	COG2814	Major facilitator Superfamily
KM404_09875	COG0840	transmembrane signaling receptor activity
KM404_09890	COG3949	Membrane
KM404_09895	COG0783	Belongs to the Dps family
KM404_09910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM404_09920	COG1231	oxidoreductase activity
KM404_09930	COG4989	oxidoreductase activity
KM404_09935	COG0523	cobalamin synthesis protein
KM404_09940	COG0456	acetyltransferase
KM404_09995	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM404_09995	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM404_10005	COG0702	epimerase
KM404_10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM404_10025	COG4166	transmembrane transport
KM404_10040	COG0406	alpha-ribazole phosphatase activity
KM404_10050	COG5337	Spore coat protein CotH
KM404_10055	COG1051	belongs to the nudix hydrolase family
KM404_10060	COG0586	Pfam SNARE associated Golgi protein
KM404_10065	COG2244	polysaccharide biosynthetic process
KM404_10075	COG0701	Predicted permease
KM404_10080	COG3689	TIGRFAM TIGR03943 family protein
KM404_10085	COG1607	acyl-coa hydrolase
KM404_10095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM404_10110	COG0702	epimerase
KM404_10115	COG2839	Protein conserved in bacteria
KM404_10120	COG1253	flavin adenine dinucleotide binding
KM404_10135	COG1114	Component of the transport system for branched-chain amino acids
KM404_10140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM404_10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM404_10170	COG1876	peptidase activity
KM404_10180	COG0154	amidase activity
KM404_10185	COG2211	Major facilitator Superfamily
KM404_10205	COG0561	phosphatase activity
KM404_10215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM404_10220	COG4106	trans-aconitate 2-methyltransferase activity
KM404_10235	COG1819	glycosyl
KM404_10240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_10270	COG0456	acetyltransferase
KM404_10320	COG3874	Sporulation protein YtfJ
KM404_10345	COG2226	methyltransferase
KM404_10370	COG0346	lactoylglutathione lyase activity
KM404_10380	COG0604	alcohol dehydrogenase
KM404_10385	COG1595	DNA-templated transcription, initiation
KM404_10410	COG0386	Belongs to the glutathione peroxidase family
KM404_10415	COG1305	Transglutaminase-like
KM404_10420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM404_10425	COG0714	Associated with various cellular activities
KM404_10440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM404_10445	COG1140	nitrate reductase beta subunit
KM404_10450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM404_10455	COG2181	nitrate reductase activity
KM404_10475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM404_10480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM404_10485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM404_10490	COG0303	'Molybdopterin
KM404_10495	COG0314	molybdopterin synthase activity
KM404_10505	COG2223	nitrite transmembrane transporter activity
KM404_10520	COG1648	precorrin-2 dehydrogenase activity
KM404_10530	COG1587	Uroporphyrinogen-III synthase
KM404_10530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM404_10535	COG2146	nitrite reductase [NAD(P)H] activity
KM404_10540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM404_10545	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM404_10580	COG2359	stage V sporulation protein S
KM404_10595	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM404_10610	COG1418	mRNA catabolic process
KM404_10615	COG0488	(ABC) transporter
KM404_10630	COG0629	single-stranded DNA binding
KM404_10645	COG1413	lyase activity
KM404_10660	COG2136	Putative SAM-dependent methyltransferase
KM404_10660	COG2521	methyltransferase
KM404_10665	COG0018	arginyl-trna synthetase
KM404_10690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM404_10710	COG0017	Asparaginyl-tRNA synthetase
KM404_10730	COG1674	ftsk spoiiie
KM404_10800	COG1929	Belongs to the glycerate kinase type-1 family
KM404_10805	COG0471	metal ion transport
KM404_10810	COG0745	RESPONSE REGULATOR receiver
KM404_10815	COG5002	protein histidine kinase activity
KM404_10815	COG3850	Histidine kinase
KM404_10830	COG0733	neurotransmitter:sodium symporter activity
KM404_10855	COG2610	gluconate transmembrane transporter activity
KM404_10860	COG1454	alcohol dehydrogenase
KM404_10865	COG1794	racemase activity, acting on amino acids and derivatives
KM404_10875	COG0456	acetyltransferase
KM404_10890	COG1131	(ABC) transporter
KM404_10905	COG0546	phosphoglycolate phosphatase activity
KM404_10925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM404_10940	COG0768	penicillin binding
KM404_10945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM404_10950	COG0204	Acyl-transferase
KM404_10955	COG1272	protein, Hemolysin III
KM404_10965	COG0805	protein transport
KM404_10975	COG1307	EDD domain protein, DegV family
KM404_10980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM404_10985	COG1999	signal sequence binding
KM404_10990	COG0071	Belongs to the small heat shock protein (HSP20) family
KM404_10995	COG0367	asparagine synthase
KM404_11010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM404_11040	COG1051	belongs to the nudix hydrolase family
KM404_11050	COG0668	transmembrane transport
KM404_11055	COG2203	Gaf domain
KM404_11055	COG4585	Histidine kinase
KM404_11060	COG2197	response regulator
KM404_11070	COG1064	alcohol dehydrogenase
KM404_11095	COG1070	Carbohydrate kinase
KM404_11100	COG1070	Carbohydrate kinase
KM404_11130	COG1125	glycine betaine transport
KM404_11130	COG0517	IMP dehydrogenase activity
KM404_11135	COG1174	glycine betaine transport
KM404_11170	COG1253	flavin adenine dinucleotide binding
KM404_11175	COG1012	belongs to the aldehyde dehydrogenase family
KM404_11180	COG5506	Protein of unknown function (DUF1694)
KM404_11195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM404_11200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM404_11210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM404_11215	COG0456	acetyltransferase
KM404_11220	COG3829	transcription factor binding
KM404_11225	COG1509	lysine 2,3-aminomutase activity
KM404_11265	COG4326	sporulation control protein
KM404_11270	COG0671	phosphoesterase, PA-phosphatase related
KM404_11275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM404_11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM404_11310	COG1787	Restriction endonuclease
KM404_11310	COG1715	Restriction endonuclease
KM404_11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM404_11440	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM404_11440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM404_11445	COG2814	Major facilitator Superfamily
KM404_11450	COG4841	protein insertion into membrane
KM404_11455	COG0372	Belongs to the citrate synthase family
KM404_11460	COG2079	MmgE PrpD family protein
KM404_11465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM404_11470	COG1960	acyl-CoA dehydrogenase activity
KM404_11475	COG2084	Dehydrogenase
KM404_11485	COG1280	lysine exporter protein (LysE YggA)
KM404_11490	COG1024	Enoyl-CoA hydratase
KM404_11505	COG0420	3'-5' exonuclease activity
KM404_11510	COG0419	ATPase involved in DNA repair
KM404_11530	COG2223	nitrite transmembrane transporter activity
KM404_11535	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_11540	COG1169	isochorismate synthase
KM404_11545	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM404_11550	COG3433	isochorismatase activity
KM404_11550	COG1535	isochorismatase
KM404_11555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM404_11560	COG3251	PFAM MbtH domain protein
KM404_11565	COG2814	Major facilitator Superfamily
KM404_11580	COG0776	regulation of translation
KM404_11590	COG2318	DinB family
KM404_11600	COG1115	amino acid carrier protein
KM404_11615	COG2329	Antibiotic biosynthesis monooxygenase
KM404_11620	COG1187	pseudouridine synthase activity
KM404_11625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM404_11640	COG0596	Alpha beta hydrolase
KM404_11645	COG2814	Major facilitator Superfamily
KM404_11665	COG2226	methyltransferase
KM404_11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_11745	COG1247	-acetyltransferase
KM404_11775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM404_11785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_11795	COG1278	Cold shock
KM404_11810	COG0010	Belongs to the arginase family
KM404_11815	COG0561	phosphatase activity
KM404_11855	COG0583	DNA-binding transcription factor activity
KM404_11860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM404_11875	COG0583	DNA-binding transcription factor activity
KM404_11880	COG2258	MOSC domain
KM404_11895	COG1132	(ABC) transporter
KM404_11900	COG1132	(ABC) transporter
KM404_11920	COG1396	sequence-specific DNA binding
KM404_11945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM404_11950	COG1595	DNA-templated transcription, initiation
KM404_11975	COG1649	PFAM Uncharacterised BCR, COG1649
KM404_12000	COG2971	BadF BadG BcrA BcrD
KM404_12005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM404_12010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM404_12030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_12060	COG1309	transcriptional regulator
KM404_12075	COG1136	(ABC) transporter
KM404_12075	COG0577	efflux transmembrane transporter activity
KM404_12080	COG0500	methyltransferase
KM404_12080	COG3615	Tellurite resistance protein tehB
KM404_12090	COG2226	methyltransferase
KM404_12095	COG3961	Belongs to the TPP enzyme family
KM404_12100	COG1846	Transcriptional regulator
KM404_12140	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM404_12155	COG1595	DNA-templated transcription, initiation
KM404_12165	COG0768	penicillin binding
KM404_12175	COG2367	Beta-lactamase
KM404_12180	COG0671	phosphoesterase, PA-phosphatase related
KM404_12185	COG1609	Transcriptional regulator
KM404_12190	COG2814	Major facilitator Superfamily
KM404_12195	COG0673	inositol 2-dehydrogenase activity
KM404_12205	COG1012	belongs to the aldehyde dehydrogenase family
KM404_12220	COG0191	fructose-bisphosphate aldolase activity
KM404_12225	COG3718	enzyme involved in inositol metabolism
KM404_12250	COG0457	Tetratricopeptide repeat
KM404_12255	COG1476	TRANSCRIPTIONal
KM404_12270	COG1876	peptidase activity
KM404_12290	COG1309	transcriptional regulator
KM404_12295	COG0488	(ABC) transporter
KM404_12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_12325	COG1252	NADH dehydrogenase
KM404_12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_12345	COG1131	(ABC) transporter
KM404_12355	COG1309	transcriptional regulator
KM404_12370	COG1960	acyl-CoA dehydrogenase activity
KM404_12375	COG0439	Biotin carboxylase
KM404_12380	COG0511	ligase activity, forming carbon-carbon bonds
KM404_12385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM404_12390	COG1024	Enoyl-CoA hydratase
KM404_12395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM404_12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM404_12410	COG1247	-acetyltransferase
KM404_12415	COG0572	uridine kinase
KM404_12425	COG2318	DinB family
KM404_12430	COG1686	Belongs to the peptidase S11 family
KM404_12455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM404_12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM404_12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM404_12520	COG2814	Major facilitator Superfamily
KM404_12540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM404_12560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_12575	COG1063	alcohol dehydrogenase
KM404_12605	COG3773	Cell wall hydrolase
KM404_12615	COG0745	RESPONSE REGULATOR receiver
KM404_12630	COG0488	(ABC) transporter
KM404_12645	COG1136	(ABC) transporter
KM404_12670	COG0460	homoserine dehydrogenase
KM404_12675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_12685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM404_12750	COG2124	cytochrome p450
KM404_12785	COG0561	phosphatase activity
KM404_12795	COG5002	protein histidine kinase activity
KM404_12800	COG0768	penicillin binding
KM404_12805	COG1819	glycosyl
KM404_12810	COG1794	racemase activity, acting on amino acids and derivatives
KM404_12820	COG1122	ATPase activity
KM404_12835	COG2205	protein histidine kinase activity
KM404_12845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM404_12850	COG0604	alcohol dehydrogenase
KM404_12855	COG0768	penicillin binding
KM404_12865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM404_12900	COG0693	protein deglycase activity
KM404_12930	COG2814	Major facilitator Superfamily
KM404_12945	COG0584	glycerophosphoryl diester phosphodiesterase
KM404_12965	COG0697	spore germination
KM404_12990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM404_13000	COG2223	nitrite transmembrane transporter activity
KM404_13015	COG2816	NAD+ diphosphatase activity
KM404_13020	COG0592	DNA-directed DNA polymerase activity
KM404_13025	COG1051	belongs to the nudix hydrolase family
KM404_13060	COG3878	Protein conserved in bacteria
KM404_13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM404_13120	COG0322	excinuclease ABC activity
KM404_13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM404_13185	COG1011	Hydrolase
KM404_13205	COG0076	glutamate decarboxylase activity
KM404_13220	COG1523	belongs to the glycosyl hydrolase 13 family
KM404_13225	COG3227	Zinc metalloprotease (Elastase)
KM404_13245	COG0201	protein transport
KM404_13255	COG0697	spore germination
KM404_13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_13290	COG4129	membrane
KM404_13295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_13310	COG2959	enzyme of heme biosynthesis
KM404_13330	COG3483	tryptophan 2,3-dioxygenase activity
KM404_13335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM404_13340	COG3844	kynureninase activity
KM404_13345	COG1309	transcriptional regulator
KM404_13375	COG3284	Transcriptional regulator
KM404_13395	COG1349	DNA-binding transcription factor activity
KM404_13415	COG1959	2 iron, 2 sulfur cluster binding
KM404_13430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM404_13435	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM404_13440	COG0022	dehydrogenase e1 component
KM404_13445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM404_13455	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_13460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM404_13460	COG0456	acetyltransferase
KM404_13490	COG4176	ABC-type proline glycine betaine transport system permease component
KM404_13495	COG0517	IMP dehydrogenase activity
KM404_13495	COG4175	Glycine betaine
KM404_13520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM404_13525	COG2153	protein acetylation
KM404_13530	COG3397	chitin binding
KM404_13545	COG2205	protein histidine kinase activity
KM404_13570	COG0658	competence protein
KM404_13570	COG2333	competence protein COMEC
KM404_13620	COG3973	AAA domain
KM404_13635	COG2105	PFAM AIG2 family protein
KM404_13640	COG0514	ATP-dependent DNA helicase (RecQ)
KM404_13660	COG4637	Psort location Cytoplasmic, score
KM404_13685	COG3397	chitin binding
KM404_13700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM404_13705	COG1115	amino acid carrier protein
KM404_13710	COG1012	belongs to the aldehyde dehydrogenase family
KM404_13715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM404_13725	COG3938	Belongs to the proline racemase family
KM404_13730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM404_13770	COG0586	Pfam SNARE associated Golgi protein
KM404_13785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM404_13790	COG0519	Catalyzes the synthesis of GMP from XMP
KM404_13795	COG4166	transmembrane transport
KM404_13805	COG4948	Mandelate Racemase Muconate Lactonizing
KM404_13850	COG2936	dipeptidyl-peptidase activity
KM404_13855	COG5002	protein histidine kinase activity
KM404_13895	COG1164	Oligoendopeptidase f
KM404_13910	COG1307	EDD domain protein, DegV family
KM404_13930	COG2814	Major facilitator Superfamily
KM404_13940	COG1664	Polymer-forming cytoskeletal
KM404_13945	COG0789	Transcriptional regulator
KM404_13950	COG4533	DNA binding
KM404_13955	COG0477	Major facilitator Superfamily
KM404_13955	COG2814	Major facilitator Superfamily
KM404_13975	COG2261	transglycosylase associated protein
KM404_13990	COG2226	methyltransferase
KM404_14025	COG0436	Aminotransferase
KM404_14030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM404_14035	COG5146	pantothenate kinase activity
KM404_14055	COG1131	(ABC) transporter
KM404_14100	COG0628	permease
KM404_14110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM404_14115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM404_14120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM404_14125	COG1116	anion transmembrane transporter activity
KM404_14145	COG2816	NAD+ diphosphatase activity
KM404_14165	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM404_14190	COG0697	spore germination
KM404_14195	COG2318	DinB family
KM404_14215	COG4912	Dna alkylation repair
KM404_14235	COG0861	Integral membrane protein TerC family
KM404_14240	COG1368	sulfuric ester hydrolase activity
KM404_14245	COG0488	(ABC) transporter
KM404_14255	COG2409	Drug exporters of the RND superfamily
KM404_14255	COG1033	growth of symbiont in host cell
KM404_14260	COG1033	growth of symbiont in host cell
KM404_14260	COG2409	Drug exporters of the RND superfamily
KM404_14265	COG1033	growth of symbiont in host cell
KM404_14265	COG2409	Drug exporters of the RND superfamily
KM404_14270	COG1309	transcriptional regulator
KM404_14285	COG0287	Prephenate dehydrogenase
KM404_14290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM404_14295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM404_14300	COG1605	Chorismate mutase
KM404_14300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM404_14335	COG3584	3D domain protein
KM404_14335	COG1388	LysM domain
KM404_14345	COG1595	DNA-templated transcription, initiation
KM404_14370	COG1879	ABC-type sugar transport system periplasmic component
KM404_14380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM404_14390	COG2390	Transcriptional regulator
KM404_14395	COG1070	Carbohydrate kinase
KM404_14425	COG2329	Antibiotic biosynthesis monooxygenase
KM404_14445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_14455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM404_14460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM404_14465	COG4187	Peptidase family M20/M25/M40
KM404_14470	COG1414	Transcriptional regulator
KM404_14475	COG0833	amino acid
KM404_14480	COG1690	Belongs to the RtcB family
KM404_14485	COG3239	Fatty acid desaturase
KM404_14490	COG1785	Belongs to the alkaline phosphatase family
KM404_14500	COG3655	Transcriptional regulator
KM404_14515	COG4377	Putative membrane peptidase family (DUF2324)
KM404_14525	COG3279	Response regulator of the LytR AlgR family
KM404_14535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_14540	COG0346	lactoylglutathione lyase activity
KM404_14560	COG0714	Associated with various cellular activities
KM404_14585	COG0463	Glycosyl transferase, family 2
KM404_14610	COG0463	Glycosyl transferase, family 2
KM404_14620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM404_14625	COG0753	catalase activity
KM404_14635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM404_14660	COG0714	Associated with various cellular activities
KM404_14670	COG0778	Nitroreductase
KM404_14675	COG1846	Transcriptional regulator
KM404_14710	COG1725	Transcriptional regulator
KM404_14720	COG0577	efflux transmembrane transporter activity
KM404_14720	COG1136	(ABC) transporter
KM404_14745	COG2207	Transcriptional regulator
KM404_14750	COG0456	acetyltransferase
KM404_14770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_14790	COG0642	Histidine kinase
KM404_14795	COG0745	RESPONSE REGULATOR receiver
KM404_14800	COG0596	Alpha beta hydrolase
KM404_14830	COG0730	response to heat
KM404_14840	COG0833	amino acid
KM404_14850	COG4335	DNA alkylation repair
KM404_14890	COG0768	penicillin binding
KM404_14900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM404_14930	COG1984	allophanate hydrolase subunit 2
KM404_14935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM404_14940	COG1414	Transcriptional regulator
KM404_14955	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM404_14960	COG0640	Transcriptional regulator
KM404_14970	COG1960	acyl-CoA dehydrogenase activity
KM404_14985	COG3314	Sporulation integral membrane protein YlbJ
KM404_15000	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM404_15015	COG0574	Belongs to the PEP-utilizing enzyme family
KM404_15015	COG3848	Pyruvate phosphate dikinase
KM404_15020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_15035	COG5577	PFAM Coat F domain
KM404_15040	COG3403	YqcI/YcgG family
KM404_15045	COG1280	lysine exporter protein (LysE YggA)
KM404_15080	COG1063	alcohol dehydrogenase
KM404_15095	COG1027	Aspartate ammonia-lyase
KM404_15100	COG0252	asparaginase activity
KM404_15105	COG1396	sequence-specific DNA binding
KM404_15115	COG0322	excinuclease ABC activity
KM404_15120	COG0531	amino acid
KM404_15125	COG1114	Component of the transport system for branched-chain amino acids
KM404_15130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM404_15140	COG0281	malic enzyme
KM404_15155	COG0531	amino acid
KM404_15165	COG0784	Response regulator, receiver
KM404_15175	COG2066	Belongs to the glutaminase family
KM404_15180	COG1115	amino acid carrier protein
KM404_15210	COG0737	Belongs to the 5'-nucleotidase family
KM404_15215	COG0753	catalase activity
KM404_15220	COG2267	carboxylic ester hydrolase activity
KM404_15225	COG1335	isochorismatase
KM404_15245	COG0583	DNA-binding transcription factor activity
KM404_15250	COG1846	Transcriptional regulator
KM404_15290	COG0415	Belongs to the DNA photolyase family
KM404_15295	COG0288	reversible hydration of carbon dioxide
KM404_15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM404_15310	COG5609	conserved protein (DUF2294)
KM404_15325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM404_15330	COG2267	carboxylic ester hydrolase activity
KM404_15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM404_15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM404_15345	COG1121	(ABC) transporter
KM404_15375	COG0798	PFAM Bile acid sodium symporter
KM404_15380	COG0346	lactoylglutathione lyase activity
KM404_15385	COG0640	Transcriptional regulator
KM404_15400	COG0443	Heat shock 70 kDa protein
KM404_15415	COG1522	sequence-specific DNA binding
KM404_15430	COG0346	lactoylglutathione lyase activity
KM404_15455	COG2169	Transcriptional regulator
KM404_15500	COG2814	Major facilitator Superfamily
KM404_15525	COG0745	RESPONSE REGULATOR receiver
KM404_15530	COG3850	Histidine kinase
KM404_15530	COG5002	protein histidine kinase activity
KM404_15555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM404_15575	COG1476	TRANSCRIPTIONal
KM404_15590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_15595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM404_15605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_15610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM404_15625	COG1136	(ABC) transporter
KM404_15630	COG0577	efflux transmembrane transporter activity
KM404_15645	COG5002	protein histidine kinase activity
KM404_15645	COG3850	Histidine kinase
KM404_15655	COG2364	Membrane
KM404_15660	COG1846	Transcriptional regulator
KM404_15670	COG2808	Putative FMN-binding domain
KM404_15675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_15680	COG2271	Major facilitator Superfamily
KM404_15685	COG1556	Lactate utilization protein
KM404_15690	COG1139	Iron-sulfur cluster binding protein
KM404_15700	COG0583	DNA-binding transcription factor activity
KM404_15710	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM404_15730	COG0738	Major facilitator superfamily
KM404_15735	COG0673	inositol 2-dehydrogenase activity
KM404_15740	COG0561	phosphatase activity
KM404_15750	COG1609	Transcriptional regulator
KM404_15755	COG0457	Tetratricopeptide repeat
KM404_15775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM404_15805	COG0534	Mate efflux family protein
KM404_15825	COG2814	Major facilitator Superfamily
KM404_15830	COG1309	transcriptional regulator
KM404_15845	COG0814	amino acid
KM404_15850	COG1760	l-serine dehydratase
KM404_15855	COG1760	l-serine dehydratase
KM404_15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM404_15870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM404_15880	COG1335	isochorismatase
KM404_15885	COG1522	sequence-specific DNA binding
KM404_15890	COG0531	amino acid
KM404_15905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM404_15925	COG1595	DNA-templated transcription, initiation
KM404_15940	COG0662	Cupin 2, conserved barrel domain protein
KM404_15945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_15945	COG2207	Transcriptional regulator
KM404_15995	COG0477	Major facilitator Superfamily
KM404_16005	COG1846	Transcriptional regulator
KM404_16010	COG2814	Major facilitator Superfamily
KM404_16020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM404_16025	COG1131	(ABC) transporter
KM404_16045	COG2076	Multidrug Resistance protein
KM404_16050	COG1309	transcriptional regulator
KM404_16060	COG2031	fatty acid transporter
KM404_16070	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM404_16100	COG1122	ATPase activity
KM404_16105	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM404_16120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM404_16125	COG1288	antiporter activity
KM404_16130	COG2356	endonuclease I
KM404_16145	COG3620	sequence-specific DNA binding
KM404_16150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM404_16155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM404_16160	COG0124	histidyl-tRNA synthetase
KM404_16175	COG1733	regulation of RNA biosynthetic process
KM404_16180	COG0778	Nitroreductase
KM404_16200	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_16210	COG1131	(ABC) transporter
KM404_16235	COG1011	Hydrolase
KM404_16245	COG2365	Tyrosine phosphatase family
KM404_16270	COG0346	lactoylglutathione lyase activity
KM404_16275	COG1940	carbohydrate kinase activity
KM404_16280	COG0738	Major facilitator superfamily
KM404_16285	COG0110	maltose O-acetyltransferase activity
KM404_16295	COG0577	efflux transmembrane transporter activity
KM404_16295	COG1136	(ABC) transporter
KM404_16310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM404_16315	COG0628	permease
KM404_16335	COG2226	methyltransferase
KM404_16345	COG0477	Major facilitator Superfamily
KM404_16375	COG1253	flavin adenine dinucleotide binding
KM404_16380	COG0789	Transcriptional regulator
KM404_16385	COG0697	spore germination
KM404_16390	COG1357	PFAM Pentapeptide repeats (8 copies)
KM404_16395	COG3813	Protein conserved in bacteria
KM404_16400	COG2706	6-phosphogluconolactonase activity
KM404_16405	COG1070	Carbohydrate kinase
KM404_16415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM404_16420	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM404_16430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM404_16435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM404_16440	COG0604	alcohol dehydrogenase
KM404_16445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM404_16455	COG0604	alcohol dehydrogenase
KM404_16455	COG3321	synthase
KM404_16460	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_16485	COG0656	L-ascorbic acid biosynthetic process
KM404_16490	COG2814	Major facilitator Superfamily
KM404_16505	COG0346	lactoylglutathione lyase activity
KM404_16510	COG0814	amino acid
KM404_16535	COG1393	Belongs to the ArsC family
KM404_16540	COG1733	regulation of RNA biosynthetic process
KM404_16545	COG2188	Transcriptional regulator
KM404_16555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM404_16560	COG1733	regulation of RNA biosynthetic process
KM404_16565	COG1733	regulation of RNA biosynthetic process
KM404_16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_16600	COG0384	phenazine biosynthesis protein PhzF
KM404_16610	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_16620	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_16630	COG1733	regulation of RNA biosynthetic process
KM404_16665	COG1191	sigma factor activity
KM404_16680	COG1309	transcriptional regulator
KM404_16700	COG3152	Membrane
KM404_16725	COG1151	hydroxylamine reductase activity
KM404_16735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_16740	COG3757	hydrolase, family 25
KM404_16740	COG3409	Peptidoglycan-binding domain 1 protein
KM404_16775	COG2072	flavoprotein involved in K transport
KM404_16810	COG0604	alcohol dehydrogenase
KM404_16815	COG1113	amino acid transport
KM404_16820	COG2814	Major facilitator Superfamily
KM404_16850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM404_16855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM404_16875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_16890	COG3739	integral membrane protein
KM404_16895	COG0384	phenazine biosynthesis protein PhzF
KM404_16925	COG0583	DNA-binding transcription factor activity
KM404_16945	COG1193	negative regulation of DNA recombination
KM404_16970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM404_17000	COG0584	glycerophosphoryl diester phosphodiesterase
KM404_17025	COG0640	Transcriptional regulator
KM404_17030	COG0604	alcohol dehydrogenase
KM404_17050	COG2808	Putative FMN-binding domain
KM404_17055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM404_17065	COG0385	Bile acid
KM404_17070	COG0277	FAD linked oxidase domain protein
KM404_17100	COG1216	Glycosyl transferase, family 2
KM404_17105	COG1024	Enoyl-CoA hydratase
KM404_17115	COG1285	pathogenesis
KM404_17130	COG2514	catechol 2,3-dioxygenase activity
KM404_17135	COG2720	vancomycin resistance protein
KM404_17175	COG0716	FMN binding
KM404_17205	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_17215	COG0165	Argininosuccinate lyase
KM404_17230	COG4145	pantothenate transmembrane transporter activity
KM404_17240	COG1012	belongs to the aldehyde dehydrogenase family
KM404_17245	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_17255	COG1657	PFAM Prenyltransferase squalene oxidase
KM404_17260	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM404_17265	COG2962	Rard protein
KM404_17270	COG3326	Membrane
KM404_17285	COG0489	protein tyrosine kinase activity
KM404_17295	COG0314	molybdopterin synthase activity
KM404_17300	COG0303	'Molybdopterin
KM404_17305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM404_17310	COG2116	formate transmembrane transporter activity
KM404_17320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM404_17325	COG5609	conserved protein (DUF2294)
KM404_17330	COG2427	Protein of unknown function (DUF1641)
KM404_17335	COG3383	formate dehydrogenase (NAD+) activity
KM404_17340	COG0697	spore germination
KM404_17380	COG2226	methyltransferase
KM404_17385	COG4166	transmembrane transport
KM404_17390	COG4166	transmembrane transport
KM404_17395	COG4166	transmembrane transport
KM404_17400	COG1301	dicarboxylic acid transport
KM404_17405	COG1316	TRANSCRIPTIONal
KM404_17415	COG1595	DNA-templated transcription, initiation
KM404_17435	COG1131	(ABC) transporter
KM404_17445	COG0673	inositol 2-dehydrogenase activity
KM404_17450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM404_17455	COG0187	DNA topoisomerase II activity
KM404_17460	COG1832	CoA-binding protein
KM404_17465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM404_17470	COG0745	RESPONSE REGULATOR receiver
KM404_17485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM404_17490	COG4841	protein insertion into membrane
KM404_17495	COG0824	Thioesterase
KM404_17525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM404_17535	COG2274	protein secretion by the type I secretion system
KM404_17540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM404_17580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM404_17595	COG0183	Belongs to the thiolase family
KM404_17600	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_17605	COG1268	BioY protein
KM404_17610	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_17660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_17670	COG5002	protein histidine kinase activity
KM404_17675	COG0400	carboxylic ester hydrolase activity
KM404_17680	COG0346	lactoylglutathione lyase activity
KM404_17685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM404_17690	COG0069	glutamate synthase activity
KM404_17695	COG1902	pentaerythritol trinitrate reductase activity
KM404_17700	COG1329	Transcriptional regulator
KM404_17705	COG0010	Belongs to the arginase family
KM404_17730	COG2226	methyltransferase
KM404_17785	COG4846	Membrane protein involved in cytochrome C biogenesis
KM404_17790	COG0785	Cytochrome C biogenesis protein
KM404_17800	COG0583	DNA-binding transcription factor activity
KM404_17805	COG1380	Effector of murein hydrolase LrgA
KM404_17810	COG1346	cytolysis
KM404_17835	COG3409	Peptidoglycan-binding domain 1 protein
KM404_17835	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM404_17850	COG1132	(ABC) transporter
KM404_17855	COG1132	(ABC) transporter
KM404_17885	COG3639	organic phosphonate transmembrane transporter activity
KM404_17890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM404_17910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM404_17930	COG1695	Transcriptional regulator
KM404_17965	COG3409	Peptidoglycan-binding domain 1 protein
KM404_17965	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM404_17965	COG1388	LysM domain
KM404_17970	COG4824	toxin secretion phage lysis holin
KM404_18125	COG1595	DNA-templated transcription, initiation
KM404_18170	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM404_18250	COG1396	sequence-specific DNA binding
KM404_18275	COG0174	glutamine synthetase
KM404_18280	COG0789	Transcriptional regulator
KM404_18285	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM404_18295	COG2860	membrane
KM404_18305	COG0464	growth
KM404_18335	COG3584	3D domain protein
KM404_18335	COG1388	LysM domain
KM404_18340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM404_18340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM404_18340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM404_18345	COG1105	Belongs to the carbohydrate kinase PfkB family
KM404_18350	COG1349	DNA-binding transcription factor activity
KM404_18360	COG2322	membrane
KM404_18370	COG1113	amino acid transport
KM404_18385	COG1408	metallophosphoesterase
KM404_18390	COG2116	formate transmembrane transporter activity
KM404_18400	COG2217	Heavy metal translocating P-type atpase
KM404_18405	COG2608	mercury ion transmembrane transporter activity
KM404_18410	COG1937	Protein conserved in bacteria
KM404_18420	COG2819	hydrolase of the alpha beta superfamily
KM404_18425	COG1120	ATPase activity
KM404_18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_18445	COG0708	Exodeoxyribonuclease III
KM404_18450	COG2169	Transcriptional regulator
KM404_18455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM404_18460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM404_18470	COG2364	Membrane
KM404_18485	COG2267	carboxylic ester hydrolase activity
KM404_18490	COG0346	lactoylglutathione lyase activity
KM404_18495	COG5001	Diguanylate cyclase
KM404_18495	COG3300	MHYT domain
KM404_18510	COG1346	cytolysis
KM404_18515	COG1380	Effector of murein hydrolase LrgA
KM404_18520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM404_18525	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM404_18525	COG0596	Alpha beta hydrolase
KM404_18530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM404_18550	COG1404	Belongs to the peptidase S8 family
KM404_18555	COG3773	Cell wall hydrolase
KM404_18560	COG0562	UDP-galactopyranose mutase
KM404_18565	COG1368	sulfuric ester hydrolase activity
KM404_18570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM404_18580	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM404_18605	COG1131	(ABC) transporter
KM404_18625	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM404_18630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM404_18635	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM404_18640	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM404_18640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM404_18650	COG2359	stage V sporulation protein S
KM404_18655	COG1692	metallophosphoesterase
KM404_18680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM404_18685	COG1426	Protein conserved in bacteria
KM404_18700	COG0300	oxidoreductase activity
KM404_18705	COG0612	Peptidase, M16
KM404_18710	COG0612	Peptidase, M16
KM404_18715	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM404_18725	COG3845	ABC transporter
KM404_18730	COG1744	ABC transporter substrate-binding protein PnrA-like
KM404_18735	COG2188	Transcriptional regulator
KM404_18740	COG1674	ftsk spoiiie
KM404_18750	COG0740	serine-type endopeptidase activity
KM404_18755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM404_18765	COG0527	aspartate kinase activity
KM404_18770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM404_18775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM404_18780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM404_18785	COG1873	PFAM PRC-barrel domain
KM404_18790	COG0612	Peptidase, M16
KM404_18795	COG0726	polysaccharide deacetylase
KM404_18810	COG0196	riboflavin kinase activity
KM404_18815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM404_18825	COG1550	Protein conserved in bacteria
KM404_18835	COG1358	cellular component organization or biogenesis
KM404_18840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM404_18845	COG0195	Participates in both transcription termination and antitermination
KM404_18865	COG0750	zinc metalloprotease
KM404_18875	COG4589	Belongs to the CDS family
KM404_18880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM404_18890	COG0528	UMP kinase activity
KM404_18920	COG4974	Belongs to the 'phage' integrase family
KM404_18930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM404_18940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM404_18980	COG1837	Belongs to the UPF0109 family
KM404_18990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM404_19000	COG0552	protein localization to endoplasmic reticulum
KM404_19005	COG1196	nuclear chromosome segregation
KM404_19015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM404_19020	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_19025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM404_19040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM404_19045	COG1461	Dihydroxyacetone kinase
KM404_19050	COG1302	Protein conserved in bacteria
KM404_19065	COG1564	THIamine pyrophosphokinase
KM404_19070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM404_19075	COG1162	GTPase activity
KM404_19080	COG2815	serine threonine protein kinase
KM404_19080	COG0515	serine threonine protein kinase
KM404_19085	COG0631	protein serine/threonine phosphatase activity
KM404_19095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM404_19095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM404_19105	COG0242	peptide deformylase activity
KM404_19110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM404_19115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM404_19135	COG1561	YicC-like family, N-terminal region
KM404_19140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM404_19150	COG0006	proline dipeptidase activity
KM404_19165	COG3069	C4-dicarboxylate transmembrane transporter activity
KM404_19230	COG0564	pseudouridine synthase activity
KM404_19250	COG3599	regulation of cell shape
KM404_19255	COG2302	S4 RNA-binding domain
KM404_19260	COG0762	integral membrane protein
KM404_19270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM404_19275	COG1496	oxidoreductase activity
KM404_19280	COG1873	PFAM PRC-barrel domain
KM404_19285	COG1191	sigma factor activity
KM404_19290	COG1191	sigma factor activity
KM404_19300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM404_19305	COG0849	cell division
KM404_19310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM404_19315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM404_19325	COG0772	Belongs to the SEDS family
KM404_19340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM404_19345	COG0768	penicillin binding
KM404_19350	COG0768	penicillin binding
KM404_19355	COG4839	cell division protein FtsL
KM404_19370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM404_19385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM404_19390	COG1399	metal-binding, possibly nucleic acid-binding protein
KM404_19440	COG4824	toxin secretion phage lysis holin
KM404_19525	COG4626	Terminase
KM404_19525	COG1802	Transcriptional regulator
KM404_19615	COG0756	dUTP diphosphatase activity
KM404_19630	COG1191	sigma factor activity
KM404_19655	COG1484	DNA-dependent DNA replication
KM404_19685	COG1396	sequence-specific DNA binding
KM404_19700	COG1396	sequence-specific DNA binding
KM404_19715	COG0582	viral genome integration into host DNA
KM404_19725	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM404_19730	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM404_19735	COG3314	Sporulation integral membrane protein YlbJ
KM404_19745	COG0742	ribosomal rna small subunit methyltransferase
KM404_19760	COG3679	Belongs to the UPF0342 family
KM404_19765	COG0406	alpha-ribazole phosphatase activity
KM404_19780	COG2340	Cysteine-rich secretory protein family
KM404_19795	COG3336	cytochrome c oxidase
KM404_19830	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM404_19835	COG0772	Belongs to the SEDS family
KM404_19845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM404_19850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM404_19860	COG4896	Protein conserved in bacteria
KM404_19875	COG1217	gtp-binding protein TYPA
KM404_19885	COG0483	inositol monophosphate 1-phosphatase activity
KM404_19905	COG1982	Orn Lys Arg decarboxylase major
KM404_19950	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM404_19955	COG0022	dehydrogenase e1 component
KM404_19960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM404_19970	COG0242	peptide deformylase activity
KM404_19975	COG0561	phosphatase activity
KM404_19985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM404_19990	COG0569	domain protein
KM404_20010	COG0583	DNA-binding transcription factor activity
KM404_20015	COG0517	IMP dehydrogenase activity
KM404_20025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM404_20035	COG4703	Protein of unknown function (DUF1797)
KM404_20050	COG2200	EAL domain
KM404_20055	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_20060	COG1408	metallophosphoesterase
KM404_20070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM404_20105	COG2814	Major facilitator Superfamily
KM404_20125	COG3209	COG3209 Rhs family protein
KM404_20135	COG2205	protein histidine kinase activity
KM404_20145	COG0436	Aminotransferase
KM404_20150	COG1609	Transcriptional regulator
KM404_20155	COG3833	ABC-type maltose transport systems, permease component
KM404_20160	COG1175	transmembrane transport
KM404_20165	COG2182	Extracellular solute-binding protein
KM404_20175	COG0366	Alpha amylase catalytic
KM404_20180	COG3842	ATPase activity
KM404_20220	COG0183	Belongs to the thiolase family
KM404_20255	COG1695	Transcriptional regulator
KM404_20260	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_20270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM404_20280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM404_20285	COG0436	Aminotransferase
KM404_20305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM404_20325	COG2199	diguanylate cyclase activity
KM404_20330	COG0778	Nitroreductase
KM404_20355	COG2190	(PTS) system
KM404_20355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM404_20355	COG1263	PTS System
KM404_20360	COG3711	transcriptional antiterminator
KM404_20370	COG2188	Transcriptional regulator
KM404_20380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM404_20405	COG1547	Domain of unknown function (DUF309)
KM404_20410	COG0456	acetyltransferase
KM404_20415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM404_20420	COG4086	secreted protein
KM404_20425	COG0561	phosphatase activity
KM404_20430	COG0697	spore germination
KM404_20445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_20470	COG0733	neurotransmitter:sodium symporter activity
KM404_20490	COG1686	Belongs to the peptidase S11 family
KM404_20495	COG1725	Transcriptional regulator
KM404_20500	COG1131	(ABC) transporter
KM404_20515	COG1846	Transcriptional regulator
KM404_20530	COG0598	Magnesium transport protein CorA
KM404_20555	COG4974	Belongs to the 'phage' integrase family
KM404_20565	COG0735	belongs to the Fur family
KM404_20570	COG1300	Membrane
KM404_20590	COG0667	Aldo Keto reductase
KM404_20595	COG0656	L-ascorbic acid biosynthetic process
KM404_20600	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM404_20600	COG0456	acetyltransferase
KM404_20610	COG1525	nuclease
KM404_20610	COG0737	Belongs to the 5'-nucleotidase family
KM404_20610	COG4085	toxin activity
KM404_20620	COG0596	Alpha beta hydrolase
KM404_20625	COG2056	Na+-H+ antiporter family
KM404_20630	COG1609	Transcriptional regulator
KM404_20635	COG0456	acetyltransferase
KM404_20640	COG1073	alpha beta
KM404_20655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM404_20655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM404_20660	COG0307	riboflavin synthase, alpha
KM404_20685	COG4106	trans-aconitate 2-methyltransferase activity
KM404_20690	COG1073	alpha beta
KM404_20690	COG2226	methyltransferase
KM404_20705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM404_20715	COG1757	Na H antiporter
KM404_20720	COG0737	Belongs to the 5'-nucleotidase family
KM404_20730	COG1522	sequence-specific DNA binding
KM404_20750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM404_20760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM404_20775	COG0300	oxidoreductase activity
KM404_20785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM404_20790	COG1760	l-serine dehydratase
KM404_20795	COG1760	l-serine dehydratase
KM404_20815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM404_20825	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM404_20830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_20845	COG1376	ErfK ybiS ycfS ynhG family protein
KM404_20850	COG4129	membrane
KM404_20855	COG1126	abc transporter atp-binding protein
KM404_20860	COG0765	amino acid transport
KM404_20865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM404_20885	COG0772	Belongs to the SEDS family
KM404_20890	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM404_20895	COG0022	dehydrogenase e1 component
KM404_20900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM404_20905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM404_20920	COG0280	phosphate acetyltransferase
KM404_20925	COG3829	transcription factor binding
KM404_20925	COG3290	protein histidine kinase activity
KM404_20935	COG0584	glycerophosphoryl diester phosphodiesterase
KM404_20940	COG3093	addiction module antidote protein HigA
KM404_20950	COG0745	RESPONSE REGULATOR receiver
KM404_20955	COG0750	zinc metalloprotease
KM404_20960	COG0497	DNA recombination
KM404_20970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM404_20980	COG0142	geranyltranstransferase activity
KM404_21005	COG1302	Protein conserved in bacteria
KM404_21010	COG0439	Biotin carboxylase
KM404_21015	COG0511	ligase activity, forming carbon-carbon bonds
KM404_21060	COG3854	ATPases associated with a variety of cellular activities
KM404_21085	COG0006	proline dipeptidase activity
KM404_21100	COG3872	metal-dependent enzyme
KM404_21110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM404_21130	COG0095	Lipoate-protein ligase
KM404_21135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_21140	COG1609	Transcriptional regulator
KM404_21150	COG2076	Multidrug Resistance protein
KM404_21155	COG2076	Multidrug Resistance protein
KM404_21190	COG1131	(ABC) transporter
KM404_21195	COG1725	Transcriptional regulator
KM404_21225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM404_21280	COG4970	Tfp pilus assembly protein FimT
KM404_21290	COG1459	type II secretion system
KM404_21295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM404_21345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM404_21350	COG0646	methionine synthase
KM404_21350	COG1410	methionine synthase
KM404_21355	COG0646	methionine synthase
KM404_21355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM404_21360	COG0626	cystathionine gamma-synthase activity
KM404_21365	COG0626	cystathionine gamma-synthase activity
KM404_21385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_21395	COG1940	carbohydrate kinase activity
KM404_21400	COG4483	Protein conserved in bacteria
KM404_21405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM404_21410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM404_21415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM404_21420	COG0704	Plays a role in the regulation of phosphate uptake
KM404_21430	COG0581	inorganic phosphate transmembrane transporter activity
KM404_21435	COG0573	inorganic phosphate transmembrane transporter activity
KM404_21440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM404_21445	COG0768	penicillin binding
KM404_21450	COG0477	Major facilitator Superfamily
KM404_21455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM404_21480	COG0735	belongs to the Fur family
KM404_21485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM404_21490	COG1121	(ABC) transporter
KM404_21495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_21525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM404_21530	COG2384	SAM-dependent methyltransferase
KM404_21535	COG2010	Cytochrome c
KM404_21540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM404_21545	COG0358	DNA primase activity
KM404_21555	COG0517	IMP dehydrogenase activity
KM404_21570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM404_21575	COG0295	cytidine deaminase activity
KM404_21580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM404_21590	COG1480	7TM receptor with intracellular HD hydrolase
KM404_21595	COG1702	phosphate starvation-inducible protein PhoH
KM404_21610	COG1610	YqeY-like protein
KM404_21615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM404_21620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM404_21625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM404_21655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM404_21660	COG1733	regulation of RNA biosynthetic process
KM404_21685	COG1466	dna polymerase III delta subunit
KM404_21695	COG2333	competence protein COMEC
KM404_21695	COG0658	competence protein
KM404_21700	COG2131	deaminase
KM404_21705	COG1555	photosystem II stabilization
KM404_21705	COG1596	polysaccharide export
KM404_21710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM404_21715	COG2226	methyltransferase
KM404_21720	COG0799	negative regulation of ribosome biogenesis
KM404_21725	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM404_21735	COG1534	Rna-binding protein
KM404_21745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM404_21750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM404_21775	COG1595	DNA-templated transcription, initiation
KM404_21785	COG0778	Nitroreductase
KM404_21790	COG2357	RelA SpoT domain protein
KM404_21800	COG1785	Belongs to the alkaline phosphatase family
KM404_21810	COG2267	carboxylic ester hydrolase activity
KM404_21845	COG1404	Belongs to the peptidase S8 family
KM404_21850	COG3186	Phenylalanine-4-hydroxylase
KM404_21865	COG2259	Doxx family
KM404_21905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_21915	COG1012	belongs to the aldehyde dehydrogenase family
KM404_21915	COG1454	alcohol dehydrogenase
KM404_21920	COG0626	cystathionine gamma-synthase activity
KM404_21925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM404_21950	COG0768	penicillin binding
KM404_21965	COG0826	peptidase U32
KM404_21970	COG0826	peptidase U32
KM404_21975	COG4122	O-methyltransferase activity
KM404_21980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM404_22000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM404_22010	COG0628	permease
KM404_22030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM404_22040	COG0482	sulfurtransferase activity
KM404_22045	COG1104	cysteine desulfurase activity
KM404_22050	COG1959	2 iron, 2 sulfur cluster binding
KM404_22055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM404_22065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM404_22090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM404_22100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM404_22100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM404_22105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM404_22110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM404_22110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM404_22120	COG2244	polysaccharide biosynthetic process
KM404_22125	COG2323	membrane
KM404_22135	COG1862	Preprotein translocase
KM404_22165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM404_22175	COG0697	spore germination
KM404_22180	COG0697	spore germination
KM404_22185	COG0640	Transcriptional regulator
KM404_22210	COG0157	Belongs to the NadC ModD family
KM404_22215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM404_22220	COG1104	cysteine desulfurase activity
KM404_22225	COG1827	regulation of RNA biosynthetic process
KM404_22230	COG2258	MOSC domain
KM404_22235	COG0077	Prephenate dehydratase
KM404_22240	COG0577	efflux transmembrane transporter activity
KM404_22245	COG0577	efflux transmembrane transporter activity
KM404_22250	COG1136	(ABC) transporter
KM404_22260	COG0745	RESPONSE REGULATOR receiver
KM404_22265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM404_22270	COG3290	protein histidine kinase activity
KM404_22280	COG2868	ribosomal protein
KM404_22290	COG1530	ribonuclease E activity
KM404_22295	COG1994	Peptidase M50
KM404_22300	COG0739	heme binding
KM404_22305	COG2894	cell division
KM404_22325	COG1077	Cell shape determining protein MreB Mrl
KM404_22345	COG0285	dihydrofolate synthase activity
KM404_22350	COG0525	valine-tRNA ligase activity
KM404_22360	COG1388	LysM domain
KM404_22370	COG0113	porphobilinogen synthase activity
KM404_22375	COG1587	Uroporphyrinogen-III synthase
KM404_22385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM404_22395	COG1846	Transcriptional regulator
KM404_22400	COG1764	response to oxidative stress
KM404_22415	COG1067	ATP-dependent peptidase activity
KM404_22415	COG0470	DNA polymerase III
KM404_22460	COG0622	Phosphoesterase
KM404_22475	COG5401	PFAM Sporulation and spore germination
KM404_22495	COG1309	transcriptional regulator
KM404_22510	COG2197	response regulator
KM404_22515	COG2233	PERMEase
KM404_22525	COG0402	S-adenosylhomocysteine deaminase activity
KM404_22530	COG0402	S-adenosylhomocysteine deaminase activity
KM404_22540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM404_22550	COG0444	Belongs to the ABC transporter superfamily
KM404_22555	COG4608	Belongs to the ABC transporter superfamily
KM404_22560	COG3275	phosphorelay sensor kinase activity
KM404_22565	COG3279	Response regulator of the LytR AlgR family
KM404_22580	COG1983	PspC domain protein
KM404_22585	COG1396	sequence-specific DNA binding
KM404_22590	COG0697	spore germination
KM404_22600	COG1959	2 iron, 2 sulfur cluster binding
KM404_22605	COG1668	transmembrane transport
KM404_22610	COG4152	abc transporter atp-binding protein
KM404_22615	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM404_22625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM404_22630	COG1876	peptidase activity
KM404_22635	COG0824	Thioesterase
KM404_22640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM404_22645	COG1053	succinate dehydrogenase
KM404_22650	COG2009	succinate dehydrogenase
KM404_22655	COG1719	4-vinyl reductase, 4VR
KM404_22665	COG3118	belongs to the thioredoxin family
KM404_22670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM404_22675	COG2086	electron transfer activity
KM404_22680	COG1024	Enoyl-CoA hydratase
KM404_22685	COG1309	transcriptional regulator
KM404_22690	COG0318	PFAM AMP-dependent synthetase and ligase
KM404_22710	COG2318	DinB family
KM404_22740	COG1131	(ABC) transporter
KM404_22745	COG2205	protein histidine kinase activity
KM404_22750	COG0745	RESPONSE REGULATOR receiver
KM404_22760	COG4895	conserved protein (DUF2196)
KM404_22765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM404_22780	COG4509	Sortase family
KM404_22785	COG1120	ATPase activity
KM404_22800	COG5386	Cell surface protein
KM404_22810	COG5386	Cell surface protein
KM404_22815	COG1114	Component of the transport system for branched-chain amino acids
KM404_22820	COG1187	pseudouridine synthase activity
KM404_22830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM404_22830	COG1796	DNA polymerase
KM404_22835	COG1286	toxin biosynthetic process
KM404_22880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM404_22890	COG1418	mRNA catabolic process
KM404_22915	COG2814	Major facilitator Superfamily
KM404_22920	COG1566	PFAM secretion protein HlyD family protein
KM404_22925	COG1309	transcriptional regulator
KM404_22930	COG1363	Peptidase, m42
KM404_22955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM404_22965	COG1484	DNA-dependent DNA replication
KM404_22970	COG3611	Membrane attachment protein
KM404_22980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM404_22985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM404_22990	COG0237	dephospho-CoA kinase activity
KM404_22995	COG1971	Probably functions as a manganese efflux pump
KM404_23005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM404_23005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM404_23010	COG5002	protein histidine kinase activity
KM404_23015	COG0745	RESPONSE REGULATOR receiver
KM404_23035	COG0538	isocitrate dehydrogenase activity
KM404_23040	COG0372	Belongs to the citrate synthase family
KM404_23050	COG0628	permease
KM404_23055	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM404_23080	COG1725	Transcriptional regulator
KM404_23085	COG0281	malic enzyme
KM404_23090	COG0587	DNA-directed DNA polymerase activity
KM404_23105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM404_23125	COG4109	DRTGG domain
KM404_23140	COG0006	proline dipeptidase activity
KM404_23175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_23180	COG0662	Cupin 2, conserved barrel domain protein
KM404_23190	COG1476	TRANSCRIPTIONal
KM404_23205	COG1028	Short-chain dehydrogenase reductase Sdr
KM404_23210	COG0589	response to stress
KM404_23250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_23270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM404_23275	COG0827	DNA restriction-modification system
KM404_23280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM404_23285	COG3874	Sporulation protein YtfJ
KM404_23300	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM404_23310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM404_23325	COG1104	cysteine desulfurase activity
KM404_23335	COG0583	DNA-binding transcription factor activity
KM404_23340	COG0697	spore germination
KM404_23350	COG1956	GAF domain-containing protein
KM404_23355	COG0626	cystathionine gamma-synthase activity
KM404_23385	COG1595	DNA-templated transcription, initiation
KM404_23395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM404_23400	COG0454	-acetyltransferase
KM404_23405	COG0517	IMP dehydrogenase activity
KM404_23410	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM404_23420	COG0745	RESPONSE REGULATOR receiver
KM404_23430	COG0666	response to abiotic stimulus
KM404_23465	COG1609	Transcriptional regulator
KM404_23470	COG4851	CamS sex pheromone cAM373 precursor
KM404_23475	COG3118	belongs to the thioredoxin family
KM404_23485	COG2309	aminopeptidase activity
KM404_23505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_23520	COG1674	ftsk spoiiie
KM404_23530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM404_23535	COG4848	Belongs to the UPF0354 family
KM404_23540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM404_23545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM404_23550	COG1363	Peptidase, m42
KM404_23560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_23575	COG0510	thiamine kinase activity
KM404_23580	COG1523	belongs to the glycosyl hydrolase 13 family
KM404_23595	COG1349	DNA-binding transcription factor activity
KM404_23600	COG1187	pseudouridine synthase activity
KM404_23605	COG2244	polysaccharide biosynthetic process
KM404_23610	COG2081	HI0933 family
KM404_23615	COG2814	Major facilitator Superfamily
KM404_23625	COG3832	glyoxalase III activity
KM404_23645	COG1329	Transcriptional regulator
KM404_23655	COG4975	Glucose uptake
KM404_23670	COG0314	molybdopterin synthase activity
KM404_23675	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM404_23680	COG0303	'Molybdopterin
KM404_23690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM404_23715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM404_23725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM404_23765	COG2814	Major facilitator Superfamily
KM404_23770	COG0475	glutathione-regulated potassium exporter activity
KM404_23775	COG0490	domain, Protein
KM404_23780	COG0582	viral genome integration into host DNA
KM404_23790	COG1136	(ABC) transporter
KM404_23810	COG1242	4 iron, 4 sulfur cluster binding
KM404_23815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM404_23820	COG1131	(ABC) transporter
KM404_23830	COG1794	racemase activity, acting on amino acids and derivatives
KM404_23850	COG2267	carboxylic ester hydrolase activity
KM404_23855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM404_23860	COG0671	phosphoesterase, PA-phosphatase related
KM404_23865	COG0438	transferase activity, transferring glycosyl groups
KM404_23875	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM404_23925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM404_23930	COG5002	protein histidine kinase activity
KM404_23935	COG4191	Histidine kinase
KM404_23940	COG2267	carboxylic ester hydrolase activity
KM404_23960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM404_23965	COG1116	anion transmembrane transporter activity
KM404_23970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM404_23995	COG0494	nUDIX hydrolase
KM404_24025	COG0288	reversible hydration of carbon dioxide
KM404_24030	COG1271	oxidase subunit
KM404_24035	COG1294	oxidase, subunit
KM404_24055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_24080	COG1842	Phage shock protein A
KM404_24110	COG5002	protein histidine kinase activity
KM404_24115	COG0745	RESPONSE REGULATOR receiver
KM404_24145	COG1597	lipid kinase activity
KM404_24180	COG0586	Pfam SNARE associated Golgi protein
KM404_24190	COG0577	efflux transmembrane transporter activity
KM404_24195	COG1136	(ABC) transporter
KM404_24200	COG3708	Transcriptional regulator
KM404_24200	COG2207	Transcriptional regulator
KM404_24205	COG0745	RESPONSE REGULATOR receiver
KM404_24210	COG2205	protein histidine kinase activity
KM404_24215	COG0577	efflux transmembrane transporter activity
KM404_24225	COG0577	efflux transmembrane transporter activity
KM404_24230	COG1136	(ABC) transporter
KM404_24250	COG2188	Transcriptional regulator
KM404_24270	COG3964	amidohydrolase
KM404_24300	COG4948	Mandelate Racemase Muconate Lactonizing
KM404_24310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM404_24315	COG0596	Alpha beta hydrolase
KM404_24320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM404_24325	COG1169	isochorismate synthase
KM404_24330	COG1575	Belongs to the MenA family. Type 1 subfamily
KM404_24335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM404_24355	COG0058	SHG alpha-glucan phosphorylase activity
KM404_24360	COG0297	glycogen (starch) synthase activity
KM404_24365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM404_24485	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM404_24520	COG1285	pathogenesis
KM404_24525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM404_24535	COG0166	Belongs to the GPI family
KM404_24540	COG2155	Conserved Protein
KM404_24545	COG1098	S1 RNA binding domain
KM404_24550	COG0436	Aminotransferase
KM404_24555	COG1522	sequence-specific DNA binding
KM404_24560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM404_24565	COG2267	carboxylic ester hydrolase activity
KM404_24575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM404_24595	COG5018	Exonuclease
KM404_24600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM404_24620	COG2050	protein possibly involved in aromatic compounds catabolism
KM404_24630	COG1268	BioY protein
KM404_24640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM404_24645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM404_24660	COG3584	3D domain protein
KM404_24675	COG1252	NADH dehydrogenase
KM404_24690	COG3708	Transcriptional regulator
KM404_24705	COG1683	Conserved Protein
KM404_24725	COG0316	Belongs to the HesB IscA family
KM404_24740	COG1252	NADH dehydrogenase
KM404_24755	COG0390	transport system, permease component
KM404_24760	COG2824	Alkylphosphonate utilization operon protein PhnA
KM404_24800	COG4837	Protein of unknown function (DUF1462)
KM404_24805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM404_24815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM404_24820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM404_24830	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM404_24835	COG0647	UMP catabolic process
KM404_24845	COG2445	Protein of unknown function DUF86
KM404_24850	COG1494	fructose-1,6-bisphosphatase
KM404_24865	COG4470	Protein conserved in bacteria
KM404_24875	COG0789	Transcriptional regulator
KM404_24880	COG4377	Putative membrane peptidase family (DUF2324)
KM404_24905	COG0739	heme binding
KM404_24915	COG3377	Domain of unknown function (DUF1805)
KM404_24920	COG0737	Belongs to the 5'-nucleotidase family
KM404_24925	COG1695	Transcriptional regulator
KM404_24935	COG0719	Fe-S assembly protein
KM404_24940	COG0822	iron-sulfur transferase activity
KM404_24945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM404_24950	COG0719	Fe-S assembly protein
KM404_24955	COG0396	ATPase activity
KM404_24960	COG1464	Belongs to the NlpA lipoprotein family
KM404_24965	COG1464	Belongs to the NlpA lipoprotein family
KM404_24970	COG2011	ABC-type metal ion transport system permease component
KM404_24975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM404_24985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM404_24990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM404_25000	COG1393	Belongs to the ArsC family
KM404_25045	COG0039	L-malate dehydrogenase activity
KM404_25065	COG1309	transcriptional regulator
KM404_25070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM404_25075	COG1960	acyl-CoA dehydrogenase activity
KM404_25080	COG0183	Belongs to the thiolase family
KM404_25085	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM404_25085	COG1024	Enoyl-CoA hydratase
KM404_25095	COG1686	Belongs to the peptidase S11 family
KM404_25110	COG0011	TIGRFAM Protein of
KM404_25115	COG0840	transmembrane signaling receptor activity
KM404_25135	COG2814	Major facilitator Superfamily
KM404_25140	COG0531	amino acid
KM404_25150	COG0706	membrane insertase activity
KM404_25160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM404_25195	COG0586	Pfam SNARE associated Golgi protein
KM404_25205	COG1376	ErfK ybiS ycfS ynhG family protein
KM404_25210	COG0745	RESPONSE REGULATOR receiver
KM404_25215	COG5002	protein histidine kinase activity
KM404_25240	COG2151	metal-sulfur cluster biosynthetic enzyme
KM404_25245	COG3227	Zinc metalloprotease (Elastase)
KM404_25250	COG1741	Belongs to the pirin family
KM404_25265	COG0475	glutathione-regulated potassium exporter activity
KM404_25270	COG0490	domain, Protein
KM404_25275	COG1115	amino acid carrier protein
KM404_25280	COG0783	Belongs to the Dps family
KM404_25295	COG1611	Belongs to the LOG family
KM404_25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_25320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_25325	COG1115	amino acid carrier protein
KM404_25330	COG1115	amino acid carrier protein
KM404_25335	COG2910	NAD(P)H-binding
KM404_25350	COG0656	L-ascorbic acid biosynthetic process
KM404_25355	COG2814	Major facilitator Superfamily
KM404_25360	COG1733	regulation of RNA biosynthetic process
KM404_25370	COG1252	NADH dehydrogenase
KM404_25375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM404_25380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM404_25390	COG3290	protein histidine kinase activity
KM404_25390	COG0840	transmembrane signaling receptor activity
KM404_25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM404_25405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM404_25420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM404_25475	COG0557	exoribonuclease II activity
KM404_25480	COG1647	Serine aminopeptidase, S33
KM404_25485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM404_25490	COG1346	cytolysis
KM404_25590	COG4695	Portal protein
KM404_25615	COG4974	Belongs to the 'phage' integrase family
KM404_25625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM404_25630	COG0149	triose-phosphate isomerase activity
KM404_25640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM404_25655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM404_25680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM404_25695	COG2323	membrane
KM404_25700	COG0740	serine-type endopeptidase activity
KM404_25705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM404_25715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM404_25725	COG1051	belongs to the nudix hydrolase family
KM404_25735	COG0492	ferredoxin-NADP+ reductase activity
KM404_25740	COG0457	Tetratricopeptide repeat
KM404_25745	COG0110	maltose O-acetyltransferase activity
KM404_25765	COG1950	PFAM Membrane protein of
KM404_25775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM404_25780	COG0556	nucleotide-excision repair
KM404_25800	COG0789	Transcriptional regulator
KM404_25825	COG2855	membrane
KM404_25830	COG0583	DNA-binding transcription factor activity
KM404_25840	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM404_25845	COG0488	(ABC) transporter
KM404_25855	COG1132	(ABC) transporter
KM404_25860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM404_25865	COG3409	Peptidoglycan-binding domain 1 protein
KM404_25865	COG0793	Belongs to the peptidase S41A family
KM404_25870	COG2177	Part of the ABC transporter FtsEX involved in
KM404_25875	COG2884	Cell division ATP-binding protein ftsE
KM404_25890	COG0653	protein targeting
KM404_25895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM404_25900	COG1278	Cold shock
KM404_25905	COG1040	competence protein
KM404_25910	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM404_25915	COG0791	NLP P60 protein
KM404_25915	COG1388	LysM domain
KM404_25920	COG1733	regulation of RNA biosynthetic process
KM404_25925	COG1307	EDD domain protein, DegV family
KM404_25930	COG1739	Uncharacterized protein family UPF0029
KM404_25935	COG1316	TRANSCRIPTIONal
KM404_25940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM404_25945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM404_25950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM404_25960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM404_25960	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM404_25975	COG3394	polysaccharide catabolic process
KM404_25980	COG1486	melibiose metabolic process
KM404_25985	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM404_25990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM404_26000	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM404_26005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM404_26010	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM404_26020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM404_26025	COG1301	dicarboxylic acid transport
KM404_26035	COG0346	lactoylglutathione lyase activity
KM404_26040	COG1511	domain protein
KM404_26045	COG0583	DNA-binding transcription factor activity
KM404_26050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM404_26065	COG1271	oxidase subunit
KM404_26070	COG1294	oxidase, subunit
KM404_26075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM404_26085	COG1620	l-lactate permease
KM404_26095	COG2389	metal-binding protein
KM404_26105	COG1368	sulfuric ester hydrolase activity
KM404_26120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM404_26130	COG1215	transferase activity, transferring glycosyl groups
KM404_26135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM404_26140	COG1388	LysM domain
KM404_26140	COG3584	3D domain protein
KM404_26165	COG4715	Zinc finger, swim domain protein
KM404_26170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM404_26210	COG0577	efflux transmembrane transporter activity
KM404_26215	COG1136	(ABC) transporter
KM404_26250	COG5002	protein histidine kinase activity
KM404_26255	COG0745	RESPONSE REGULATOR receiver
KM404_26260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM404_26275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM404_26280	COG1134	teichoic acid transport
KM404_26285	COG1682	transport, permease protein
KM404_26290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM404_26335	COG1609	Transcriptional regulator
KM404_26350	COG0739	heme binding
KM404_26370	COG2385	sporulation resulting in formation of a cellular spore
KM404_26385	COG4836	Membrane
KM404_26390	COG1007	ATP synthesis coupled electron transport
KM404_26395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM404_26400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM404_26410	COG0839	Belongs to the complex I subunit 6 family
KM404_26425	COG0649	NAD binding
KM404_26430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM404_26445	COG5001	Diguanylate cyclase
KM404_26445	COG3300	MHYT domain
KM404_26495	COG0356	it plays a direct role in the translocation of protons across the membrane
KM404_26530	COG0698	ribose 5-phosphate isomerase
KM404_26540	COG2190	(PTS) system
KM404_26545	COG2259	Doxx family
KM404_26550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM404_26565	COG0009	L-threonylcarbamoyladenylate synthase
KM404_26580	COG2890	protein-(glutamine-N5) methyltransferase activity
KM404_26600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM404_26605	COG1494	fructose-1,6-bisphosphatase
KM404_26625	COG4821	SIS domain
KM404_26635	COG3343	RNA polymerase activity
KM404_26645	COG1960	acyl-CoA dehydrogenase activity
KM404_26650	COG1960	acyl-CoA dehydrogenase activity
KM404_26655	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM404_26660	COG0183	Belongs to the thiolase family
KM404_26665	COG2181	nitrate reductase activity
KM404_26665	COG0247	lactate metabolic process
KM404_26670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM404_26680	COG5001	Diguanylate cyclase
KM404_26680	COG3300	MHYT domain
KM404_26700	COG2197	response regulator
KM404_26705	COG4585	Histidine kinase
KM404_26710	COG0842	Transport permease protein
KM404_26715	COG1131	(ABC) transporter
KM404_26720	COG0024	Methionine aminopeptidase
KM404_26730	COG2234	aminopeptidase activity
KM404_26750	COG1595	DNA-templated transcription, initiation
KM404_26755	COG0018	arginyl-trna synthetase
KM404_26760	COG4506	Protein conserved in bacteria
KM404_26765	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM404_26780	COG0010	Belongs to the arginase family
KM404_26790	COG2814	Major facilitator Superfamily
KM404_26795	COG0789	Transcriptional regulator
KM404_26800	COG0584	glycerophosphoryl diester phosphodiesterase
KM404_26805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM404_26815	COG1994	Peptidase M50
KM404_26825	COG1078	dGTPase activity
KM404_26830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM404_26835	COG1120	ATPase activity
KM404_26840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM404_26865	COG0095	Lipoate-protein ligase
KM404_26870	COG0280	phosphate acetyltransferase
KM404_26885	COG3773	Cell wall hydrolase
KM404_26895	COG2363	Small membrane protein
KM404_26905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM404_26910	COG2233	PERMEase
KM404_26915	COG0561	phosphatase activity
KM404_26920	COG2814	Major facilitator Superfamily
KM404_26930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM404_26935	COG1131	(ABC) transporter
KM404_26940	COG2755	lipolytic protein G-D-S-L family
KM404_26945	COG1609	Transcriptional regulator
KM404_26955	COG0460	homoserine dehydrogenase
KM404_26965	COG2873	o-acetylhomoserine
KM404_26975	COG1011	Hydrolase
KM404_26980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM404_26990	COG2197	response regulator
KM404_27000	COG0351	phosphomethylpyrimidine kinase
KM404_27005	COG3706	GGDEF domain
KM404_27010	COG2879	small protein
KM404_27015	COG1966	Carbon starvation protein
KM404_27020	COG3279	Response regulator of the LytR AlgR family
KM404_27025	COG0477	Major facilitator Superfamily
KM404_27050	COG0840	transmembrane signaling receptor activity
KM404_27060	COG1607	acyl-coa hydrolase
KM404_27075	COG0488	(ABC) transporter
KM404_27095	COG0463	Glycosyl transferase, family 2
KM404_27100	COG1309	transcriptional regulator
KM404_27105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM404_27110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM404_27110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM404_27115	COG0628	permease
KM404_27130	COG3279	Response regulator of the LytR AlgR family
KM404_27135	COG3275	phosphorelay sensor kinase activity
KM404_27140	COG2814	Major facilitator Superfamily
KM404_27145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM404_27150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM404_27155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM404_27175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM404_27180	COG1272	protein, Hemolysin III
KM404_27200	COG0516	GMP reductase activity
KM404_27205	COG1164	Oligoendopeptidase f
KM404_27225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM404_27230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM404_27235	COG4853	Protein conserved in bacteria
KM404_27240	COG4863	YycH protein
KM404_27245	COG5002	protein histidine kinase activity
KM404_27250	COG0745	RESPONSE REGULATOR receiver
KM404_27280	COG0305	Participates in initiation and elongation during chromosome replication
KM404_27290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM404_27295	COG4241	membrane
KM404_27305	COG0629	single-stranded DNA binding
KM404_27315	COG0012	GTP binding
KM404_27320	COG4481	Protein conserved in bacteria
KM404_27325	COG0668	transmembrane transport
KM404_27335	COG1475	DNA binding
KM404_27340	COG1192	Involved in chromosome partitioning
KM404_27365	COG1847	R3H domain protein
KM404_27370	COG0706	membrane insertase activity
KM404_27380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM404_27430	COG3344	reverse transcriptase
KM404_27510	COG3344	reverse transcriptase
KM404_27700	COG4962	Type ii secretion system protein e
KM404_27835	COG2311	Membrane
KM404_27855	COG4196	transglutaminase domain protein
KM404_27860	COG0671	phosphoesterase, PA-phosphatase related
KM404_27875	COG1215	transferase activity, transferring glycosyl groups
KM404_27880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM404_27885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM404_28045	COG2002	toxin-antitoxin pair type II binding
KM404_28055	COG4974	Belongs to the 'phage' integrase family
KM404_28110	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM404_28120	COG4974	Belongs to the 'phage' integrase family
KM404_28145	COG0457	Tetratricopeptide repeat
KM404_28350	COG0791	NLP P60 protein
KM404_28350	COG0741	lytic transglycosylase activity
KM404_28415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM404_28475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM404_28485	COG4166	transmembrane transport
KM404_28525	COG1280	lysine exporter protein (LysE YggA)
KM404_28550	COG0681	Belongs to the peptidase S26 family
KM404_28625	COG1309	transcriptional regulator
KM404_28630	COG1683	Conserved Protein
KM404_28670	COG1192	Involved in chromosome partitioning