locus-tag	class	description
KM405_00010	COG0592	DNA-directed DNA polymerase activity
KM405_00015	COG2501	S4 domain
KM405_00025	COG0187	DNA topoisomerase II activity
KM405_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM405_00065	COG0516	GMP reductase activity
KM405_00065	COG0517	IMP dehydrogenase activity
KM405_00070	COG1686	Belongs to the peptidase S11 family
KM405_00100	COG1428	Deoxynucleoside kinase
KM405_00105	COG1428	Deoxynucleoside kinase
KM405_00110	COG1335	isochorismatase
KM405_00115	COG0590	tRNA wobble adenosine to inosine editing
KM405_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM405_00180	COG1982	Orn Lys Arg decarboxylase major
KM405_00190	COG0470	DNA polymerase III
KM405_00195	COG1774	PSP1 C-terminal conserved region
KM405_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM405_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM405_00220	COG2002	toxin-antitoxin pair type II binding
KM405_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM405_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM405_00230	COG0084	hydrolase, TatD family'
KM405_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM405_00250	COG4466	Protein conserved in bacteria
KM405_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM405_00270	COG0251	oxidation-reduction process
KM405_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM405_00305	COG2002	toxin-antitoxin pair type II binding
KM405_00310	COG2244	polysaccharide biosynthetic process
KM405_00315	COG3956	TIGRFAM MazG family protein
KM405_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM405_00340	COG1098	S1 RNA binding domain
KM405_00355	COG2208	phosphoserine phosphatase activity
KM405_00360	COG0037	tRNA processing
KM405_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM405_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM405_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM405_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM405_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM405_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM405_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM405_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM405_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM405_00420	COG1396	sequence-specific DNA binding
KM405_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM405_00455	COG3880	PFAM UvrB UvrC protein
KM405_00465	COG0542	response to heat
KM405_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM405_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM405_00500	COG1045	serine acetyltransferase
KM405_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM405_00520	COG3688	RNA-binding protein containing a PIN domain
KM405_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM405_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM405_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM405_00565	COG2813	Specifically methylates the guanine in position
KM405_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM405_00580	COG1358	cellular component organization or biogenesis
KM405_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM405_00710	COG0201	protein transport
KM405_00720	COG0024	Methionine aminopeptidase
KM405_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM405_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM405_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM405_00795	COG0489	protein tyrosine kinase activity
KM405_00805	COG2194	sulfuric ester hydrolase activity
KM405_00810	COG0726	polysaccharide deacetylase
KM405_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM405_00895	COG4856	YbbR-like protein
KM405_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM405_00915	COG0596	Alpha beta hydrolase
KM405_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM405_00940	COG4946	Tricorn protease homolog
KM405_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM405_00940	COG1506	peptidase
KM405_00975	COG2011	ABC-type metal ion transport system permease component
KM405_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM405_00985	COG1464	Belongs to the NlpA lipoprotein family
KM405_00990	COG0604	alcohol dehydrogenase
KM405_01000	COG0277	FAD linked oxidase domain protein
KM405_01005	COG2271	Major facilitator Superfamily
KM405_01015	COG2814	Major facilitator Superfamily
KM405_01030	COG0601	transmembrane transport
KM405_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM405_01040	COG0444	Belongs to the ABC transporter superfamily
KM405_01045	COG4608	Belongs to the ABC transporter superfamily
KM405_01050	COG4166	transmembrane transport
KM405_01060	COG2207	Transcriptional regulator
KM405_01075	COG4166	transmembrane transport
KM405_01080	COG4166	transmembrane transport
KM405_01085	COG0656	L-ascorbic acid biosynthetic process
KM405_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM405_01105	COG4149	molybdate abc transporter
KM405_01115	COG1910	domain protein
KM405_01125	COG0583	DNA-binding transcription factor activity
KM405_01130	COG0697	spore germination
KM405_01145	COG0204	Acyl-transferase
KM405_01155	COG1609	Transcriptional regulator
KM405_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_01175	COG0084	hydrolase, TatD family'
KM405_01180	COG5298	Protein conserved in bacteria
KM405_01205	COG0488	(ABC) transporter
KM405_01220	COG0747	negative chemotaxis
KM405_01225	COG0601	transmembrane transport
KM405_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM405_01235	COG0444	Belongs to the ABC transporter superfamily
KM405_01240	COG4608	Belongs to the ABC transporter superfamily
KM405_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM405_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM405_01290	COG2814	Major facilitator Superfamily
KM405_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM405_01310	COG4294	response to UV
KM405_01315	COG0457	Tetratricopeptide repeat
KM405_01315	COG0705	Rhomboid family
KM405_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM405_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM405_01335	COG0864	Transcriptional regulator
KM405_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM405_01345	COG2183	response to ionizing radiation
KM405_01440	COG0802	atpase or kinase
KM405_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM405_01450	COG0456	acetyltransferase
KM405_01460	COG0488	(ABC) transporter
KM405_01475	COG1266	CAAX protease self-immunity
KM405_01495	COG2252	PERMEase
KM405_01505	COG5002	protein histidine kinase activity
KM405_01535	COG2226	methyltransferase
KM405_01575	COG1968	undecaprenyl-diphosphatase activity
KM405_01590	COG2205	protein histidine kinase activity
KM405_01595	COG0745	RESPONSE REGULATOR receiver
KM405_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM405_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM405_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM405_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM405_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM405_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM405_01670	COG0151	Belongs to the GarS family
KM405_01695	COG0210	DNA helicase
KM405_01705	COG4851	CamS sex pheromone cAM373 precursor
KM405_01725	COG1335	isochorismatase
KM405_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM405_01735	COG2011	ABC-type metal ion transport system permease component
KM405_01740	COG1464	Belongs to the NlpA lipoprotein family
KM405_01760	COG1846	Transcriptional regulator
KM405_01785	COG1597	lipid kinase activity
KM405_01790	COG0546	phosphoglycolate phosphatase activity
KM405_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM405_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM405_01810	COG2076	Multidrug Resistance protein
KM405_01815	COG2309	aminopeptidase activity
KM405_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM405_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM405_01850	COG4807	Protein conserved in bacteria
KM405_01875	COG1757	Na H antiporter
KM405_01880	COG1473	amidohydrolase
KM405_01895	COG0450	alkyl hydroperoxide reductase
KM405_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_01940	COG0166	Belongs to the GPI family
KM405_01975	COG5002	protein histidine kinase activity
KM405_01995	COG3541	Predicted nucleotidyltransferase
KM405_02000	COG2814	Major facilitator Superfamily
KM405_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM405_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM405_02015	COG0765	amino acid transport
KM405_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM405_02030	COG0840	transmembrane signaling receptor activity
KM405_02035	COG0840	transmembrane signaling receptor activity
KM405_02040	COG0366	Alpha amylase catalytic
KM405_02045	COG2190	(PTS) system
KM405_02045	COG1263	PTS System
KM405_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM405_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM405_02100	COG1116	anion transmembrane transporter activity
KM405_02105	COG0488	(ABC) transporter
KM405_02150	COG2270	Major facilitator Superfamily
KM405_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM405_02180	COG2310	stress, protein
KM405_02185	COG2310	stress, protein
KM405_02190	COG2310	stress, protein
KM405_02195	COG0861	Integral membrane protein TerC family
KM405_02205	COG3853	Toxic anion resistance protein (TelA)
KM405_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM405_02230	COG1295	ribonuclease BN
KM405_02235	COG2217	Heavy metal translocating P-type atpase
KM405_02240	COG0697	spore germination
KM405_02260	COG0586	Pfam SNARE associated Golgi protein
KM405_02275	COG3871	stress protein (general stress protein 26)
KM405_02280	COG0387	Pfam Sodium calcium exchanger
KM405_02290	COG0535	radical SAM domain protein
KM405_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM405_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM405_02325	COG0582	viral genome integration into host DNA
KM405_02335	COG1396	sequence-specific DNA binding
KM405_02350	COG1396	sequence-specific DNA binding
KM405_02385	COG1484	DNA-dependent DNA replication
KM405_02615	COG0101	tRNA pseudouridine synthase activity
KM405_02625	COG3829	transcription factor binding
KM405_02635	COG0833	amino acid
KM405_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM405_02670	COG1263	PTS System
KM405_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM405_02690	COG0463	Glycosyl transferase, family 2
KM405_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM405_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM405_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM405_02745	COG1228	amidohydrolase
KM405_02750	COG1090	epimerase
KM405_02780	COG1988	membrane-bound metal-dependent
KM405_02785	COG1194	a g-specific adenine glycosylase
KM405_02810	COG1132	(ABC) transporter
KM405_02815	COG4129	membrane
KM405_02820	COG0070	glutamate synthase
KM405_02820	COG0069	glutamate synthase activity
KM405_02820	COG0067	glutamate synthase
KM405_02830	COG4555	ABC transporter
KM405_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM405_02855	COG0735	belongs to the Fur family
KM405_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM405_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM405_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM405_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM405_03005	COG2766	serine protein kinase
KM405_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM405_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM405_03040	COG2268	Band 7 protein
KM405_03050	COG3290	protein histidine kinase activity
KM405_03055	COG4565	transcriptional regulatory protein
KM405_03060	COG2851	Citrate transporter
KM405_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM405_03085	COG3842	ATPase activity
KM405_03090	COG1175	transmembrane transport
KM405_03095	COG0395	ABC-type sugar transport system, permease component
KM405_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM405_03110	COG0745	RESPONSE REGULATOR receiver
KM405_03115	COG5002	protein histidine kinase activity
KM405_03125	COG4990	cell redox homeostasis
KM405_03135	COG3290	protein histidine kinase activity
KM405_03140	COG4565	transcriptional regulatory protein
KM405_03145	COG3493	citrate carrier protein
KM405_03150	COG0281	malic enzyme
KM405_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_03175	COG5002	protein histidine kinase activity
KM405_03180	COG0745	RESPONSE REGULATOR receiver
KM405_03185	COG0454	-acetyltransferase
KM405_03185	COG0456	acetyltransferase
KM405_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM405_03195	COG3383	formate dehydrogenase (NAD+) activity
KM405_03200	COG2427	Protein of unknown function (DUF1641)
KM405_03215	COG0531	amino acid
KM405_03220	COG0640	Transcriptional regulator
KM405_03225	COG2217	Heavy metal translocating P-type atpase
KM405_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM405_03245	COG3227	Zinc metalloprotease (Elastase)
KM405_03265	COG2720	vancomycin resistance protein
KM405_03270	COG1316	TRANSCRIPTIONal
KM405_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_03280	COG0346	lactoylglutathione lyase activity
KM405_03285	COG1253	flavin adenine dinucleotide binding
KM405_03290	COG1027	Aspartate ammonia-lyase
KM405_03295	COG1620	l-lactate permease
KM405_03310	COG3104	oligopeptide transport
KM405_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_03335	COG2226	methyltransferase
KM405_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM405_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM405_03355	COG4548	von Willebrand factor, type A
KM405_03360	COG0714	Associated with various cellular activities
KM405_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM405_03385	COG0531	amino acid
KM405_03390	COG2188	Transcriptional regulator
KM405_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_03395	COG1263	PTS System
KM405_03400	COG0366	Alpha amylase catalytic
KM405_03415	COG0697	spore germination
KM405_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM405_03430	COG1115	amino acid carrier protein
KM405_03435	COG1126	abc transporter atp-binding protein
KM405_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM405_03445	COG0765	amino acid transport
KM405_03450	COG0765	amino acid transport
KM405_03455	COG0833	amino acid
KM405_03480	COG2378	regulation of single-species biofilm formation
KM405_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM405_03490	COG5002	protein histidine kinase activity
KM405_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM405_03520	COG0747	negative chemotaxis
KM405_03530	COG0601	transmembrane transport
KM405_03535	COG4608	Belongs to the ABC transporter superfamily
KM405_03545	COG2271	Major facilitator Superfamily
KM405_03550	COG1846	Transcriptional regulator
KM405_03560	COG1609	Transcriptional regulator
KM405_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM405_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM405_03585	COG1879	ABC-type sugar transport system periplasmic component
KM405_03610	COG1063	alcohol dehydrogenase
KM405_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM405_03650	COG1968	undecaprenyl-diphosphatase activity
KM405_03655	COG0840	transmembrane signaling receptor activity
KM405_03660	COG3584	3D domain protein
KM405_03660	COG1388	LysM domain
KM405_03665	COG1476	TRANSCRIPTIONal
KM405_03680	COG3104	oligopeptide transport
KM405_03685	COG1114	Component of the transport system for branched-chain amino acids
KM405_03700	COG1113	amino acid transport
KM405_03705	COG2252	PERMEase
KM405_03730	COG0569	domain protein
KM405_03730	COG0475	glutathione-regulated potassium exporter activity
KM405_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM405_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM405_03755	COG0833	amino acid
KM405_03760	COG4990	cell redox homeostasis
KM405_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM405_03780	COG0697	spore germination
KM405_03785	COG0531	amino acid
KM405_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM405_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM405_03805	COG1918	ferrous iron import across plasma membrane
KM405_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM405_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM405_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM405_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM405_03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM405_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM405_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM405_03975	COG1116	anion transmembrane transporter activity
KM405_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM405_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM405_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM405_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM405_04000	COG2104	thiamine diphosphate biosynthetic process
KM405_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM405_04015	COG0351	phosphomethylpyrimidine kinase
KM405_04055	COG2205	protein histidine kinase activity
KM405_04060	COG2814	Major facilitator Superfamily
KM405_04065	COG1846	Transcriptional regulator
KM405_04080	COG2252	PERMEase
KM405_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM405_04105	COG1621	beta-fructofuranosidase activity
KM405_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_04110	COG1263	PTS System
KM405_04115	COG1609	Transcriptional regulator
KM405_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM405_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM405_04165	COG0778	Nitroreductase
KM405_04170	COG2719	SpoVR family
KM405_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM405_04200	COG1937	Protein conserved in bacteria
KM405_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM405_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM405_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM405_04235	COG0730	response to heat
KM405_04245	COG1316	TRANSCRIPTIONal
KM405_04250	COG0604	alcohol dehydrogenase
KM405_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM405_04270	COG3711	transcriptional antiterminator
KM405_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM405_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM405_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM405_04300	COG1388	LysM domain
KM405_04300	COG3584	3D domain protein
KM405_04305	COG0577	efflux transmembrane transporter activity
KM405_04310	COG1136	(ABC) transporter
KM405_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM405_04335	COG1114	Component of the transport system for branched-chain amino acids
KM405_04340	COG3546	catalase activity
KM405_04375	COG0586	Pfam SNARE associated Golgi protein
KM405_04410	COG0531	amino acid
KM405_04415	COG0475	glutathione-regulated potassium exporter activity
KM405_04425	COG1737	Transcriptional regulator
KM405_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_04435	COG1263	PTS System
KM405_04445	COG2259	Doxx family
KM405_04460	COG0697	spore germination
KM405_04465	COG1522	sequence-specific DNA binding
KM405_04480	COG2076	Multidrug Resistance protein
KM405_04485	COG1309	transcriptional regulator
KM405_04490	COG2814	Major facilitator Superfamily
KM405_04495	COG1733	regulation of RNA biosynthetic process
KM405_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM405_04510	COG4533	DNA binding
KM405_04515	COG2211	Major facilitator Superfamily
KM405_04525	COG0693	protein deglycase activity
KM405_04530	COG0693	protein deglycase activity
KM405_04530	COG0753	catalase activity
KM405_04540	COG0531	amino acid
KM405_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM405_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM405_04560	COG1132	(ABC) transporter
KM405_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM405_04575	COG0765	amino acid transport
KM405_04580	COG1126	abc transporter atp-binding protein
KM405_04595	COG0189	ligase activity
KM405_04625	COG0028	Belongs to the TPP enzyme family
KM405_04630	COG3527	Alpha-acetolactate decarboxylase
KM405_04645	COG0561	phosphatase activity
KM405_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM405_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM405_04695	COG0653	protein targeting
KM405_04700	COG2244	polysaccharide biosynthetic process
KM405_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM405_04715	COG4196	transglutaminase domain protein
KM405_04730	COG1696	Membrane protein involved in D-alanine export
KM405_04745	COG1024	Enoyl-CoA hydratase
KM405_04765	COG1363	Peptidase, m42
KM405_04785	COG3938	Belongs to the proline racemase family
KM405_04825	COG0601	transmembrane transport
KM405_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM405_04840	COG4608	Belongs to the ABC transporter superfamily
KM405_04845	COG0322	excinuclease ABC activity
KM405_04875	COG0477	Major facilitator Superfamily
KM405_04880	COG3290	protein histidine kinase activity
KM405_04885	COG4565	transcriptional regulatory protein
KM405_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM405_04920	COG0789	Transcriptional regulator
KM405_04920	COG4978	Transcriptional regulator
KM405_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM405_04975	COG0477	Major facilitator Superfamily
KM405_05020	COG3320	Male sterility
KM405_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM405_05025	COG1309	transcriptional regulator
KM405_05045	COG1183	phosphatidylcholine synthase activity
KM405_05065	COG2376	Dihydroxyacetone kinase
KM405_05075	COG2376	Dihydroxyacetone kinase
KM405_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM405_05085	COG1959	2 iron, 2 sulfur cluster binding
KM405_05115	COG2770	Histidine kinase
KM405_05115	COG3437	response regulator, receiver
KM405_05165	COG3237	CsbD-like
KM405_05190	COG1191	sigma factor activity
KM405_05200	COG2208	phosphoserine phosphatase activity
KM405_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM405_05210	COG2205	protein histidine kinase activity
KM405_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM405_05210	COG2198	Histidine kinase
KM405_05210	COG0784	Response regulator, receiver
KM405_05265	COG0420	3'-5' exonuclease activity
KM405_05270	COG4717	serine-type aminopeptidase activity
KM405_05290	COG1309	transcriptional regulator
KM405_05295	COG2814	Major facilitator Superfamily
KM405_05300	COG0346	lactoylglutathione lyase activity
KM405_05310	COG0346	lactoylglutathione lyase activity
KM405_05315	COG0457	Tetratricopeptide repeat
KM405_05320	COG2267	carboxylic ester hydrolase activity
KM405_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM405_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM405_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM405_05395	COG0477	Major facilitator Superfamily
KM405_05400	COG0477	Major facilitator Superfamily
KM405_05410	COG3973	AAA domain
KM405_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM405_05435	COG4980	gas vesicle protein
KM405_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM405_05445	COG1131	(ABC) transporter
KM405_05450	COG4473	ABC transporter
KM405_05465	COG1309	transcriptional regulator
KM405_05475	COG3402	PFAM membrane-flanked domain
KM405_05525	COG3402	PFAM membrane-flanked domain
KM405_05530	COG3428	Bacterial PH domain
KM405_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM405_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM405_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM405_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM405_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM405_05590	COG1309	transcriptional regulator
KM405_05595	COG1511	domain protein
KM405_05620	COG1609	Transcriptional regulator
KM405_05630	COG1234	tRNA 3'-trailer cleavage
KM405_05635	COG0095	Lipoate-protein ligase
KM405_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_05675	COG3209	COG3209 Rhs family protein
KM405_05720	COG1078	dGTPase activity
KM405_05730	COG1595	DNA-templated transcription, initiation
KM405_05735	COG2207	Transcriptional regulator
KM405_05735	COG3708	Transcriptional regulator
KM405_05750	COG2205	protein histidine kinase activity
KM405_05755	COG0745	RESPONSE REGULATOR receiver
KM405_05785	COG0501	Belongs to the peptidase M48B family
KM405_05790	COG0840	transmembrane signaling receptor activity
KM405_05795	COG0697	spore germination
KM405_05815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM405_05820	COG2224	Isocitrate lyase
KM405_05845	COG4903	ComK protein
KM405_05850	COG0398	Pfam SNARE associated Golgi protein
KM405_05860	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM405_05865	COG1074	ATP-dependent DNA helicase activity
KM405_05910	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM405_05935	COG0367	asparagine synthase
KM405_05940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM405_05945	COG0753	catalase activity
KM405_05950	COG0004	ammonium transporteR
KM405_05970	COG2996	Protein conserved in bacteria
KM405_05980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM405_05990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_06005	COG0561	phosphatase activity
KM405_06015	COG0542	response to heat
KM405_06025	COG2267	carboxylic ester hydrolase activity
KM405_06040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_06045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM405_06050	COG5504	Zn-dependent protease
KM405_06060	COG0180	Tryptophanyl-tRNA synthetase
KM405_06070	COG4166	transmembrane transport
KM405_06075	COG0601	transmembrane transport
KM405_06080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM405_06085	COG0444	Belongs to the ABC transporter superfamily
KM405_06090	COG4608	Belongs to the ABC transporter superfamily
KM405_06095	COG0534	Mate efflux family protein
KM405_06100	COG4166	transmembrane transport
KM405_06115	COG0861	Integral membrane protein TerC family
KM405_06120	COG4862	establishment of competence for transformation
KM405_06125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM405_06135	COG1164	Oligoendopeptidase f
KM405_06145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM405_06150	COG2346	COG2346, Truncated hemoglobins
KM405_06155	COG4116	CYTH
KM405_06165	COG2357	RelA SpoT domain protein
KM405_06175	COG0564	pseudouridine synthase activity
KM405_06195	COG0463	Glycosyl transferase, family 2
KM405_06195	COG1216	Glycosyl transferase, family 2
KM405_06215	COG0457	Tetratricopeptide repeat
KM405_06215	COG0463	Glycosyl transferase, family 2
KM405_06235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM405_06250	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM405_06295	COG2153	protein acetylation
KM405_06305	COG2382	esterase
KM405_06320	COG5492	domain, Protein
KM405_06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM405_06335	COG0512	Glutamine amidotransferase of anthranilate synthase
KM405_06335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM405_06370	COG1620	l-lactate permease
KM405_06375	COG5634	Uncharacterized conserved protein (DUF2278)
KM405_06430	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM405_06440	COG1476	TRANSCRIPTIONal
KM405_06500	COG2226	methyltransferase
KM405_06510	COG1686	Belongs to the peptidase S11 family
KM405_06515	COG0681	Belongs to the peptidase S26 family
KM405_06550	COG1012	belongs to the aldehyde dehydrogenase family
KM405_06555	COG3842	ATPase activity
KM405_06560	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM405_06565	COG1177	transmembrane transport
KM405_06570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM405_06580	COG2409	Drug exporters of the RND superfamily
KM405_06590	COG0564	pseudouridine synthase activity
KM405_06600	COG2340	Cysteine-rich secretory protein family
KM405_06605	COG0247	lactate metabolic process
KM405_06610	COG0277	FAD linked oxidase domain protein
KM405_06615	COG3835	regulator
KM405_06625	COG0745	RESPONSE REGULATOR receiver
KM405_06630	COG5002	protein histidine kinase activity
KM405_06635	COG2186	Transcriptional regulator
KM405_06655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM405_06670	COG2116	formate transmembrane transporter activity
KM405_06675	COG0861	Integral membrane protein TerC family
KM405_06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM405_06690	COG2030	dehydratase
KM405_06710	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_06715	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM405_06720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM405_06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM405_06740	COG1840	ABC-type Fe3 transport system, periplasmic component
KM405_06770	COG1349	DNA-binding transcription factor activity
KM405_06790	COG2861	carbohydrate metabolic process
KM405_06800	COG3852	Histidine kinase
KM405_06805	COG1846	Transcriptional regulator
KM405_06815	COG2318	DinB family
KM405_06820	COG5002	protein histidine kinase activity
KM405_06830	COG0720	synthase
KM405_06845	COG4873	Protein conserved in bacteria
KM405_06875	COG1780	Probably involved in ribonucleotide reductase function
KM405_06895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM405_06900	COG1725	Transcriptional regulator
KM405_06905	COG1131	(ABC) transporter
KM405_06915	COG1131	(ABC) transporter
KM405_06920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM405_06935	COG1522	sequence-specific DNA binding
KM405_06945	COG1335	isochorismatase
KM405_06955	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM405_06960	COG2070	2-Nitropropane dioxygenase
KM405_06965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM405_06975	COG1696	Membrane protein involved in D-alanine export
KM405_07000	COG0716	FMN binding
KM405_07015	COG3173	Aminoglycoside phosphotransferase
KM405_07035	COG0534	Mate efflux family protein
KM405_07040	COG1968	undecaprenyl-diphosphatase activity
KM405_07055	COG1846	Transcriptional regulator
KM405_07065	COG1301	dicarboxylic acid transport
KM405_07070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM405_07075	COG4709	membrane
KM405_07080	COG3874	Sporulation protein YtfJ
KM405_07105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM405_07110	COG0028	Belongs to the TPP enzyme family
KM405_07115	COG0440	acetolactate synthase activity
KM405_07120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM405_07130	COG0473	3-isopropylmalate dehydrogenase activity
KM405_07155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM405_07190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM405_07205	COG1183	phosphatidylcholine synthase activity
KM405_07210	COG1368	sulfuric ester hydrolase activity
KM405_07220	COG0019	diaminopimelate decarboxylase activity
KM405_07240	COG0529	Catalyzes the synthesis of activated sulfate
KM405_07245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM405_07265	COG1648	precorrin-2 dehydrogenase activity
KM405_07270	COG0733	neurotransmitter:sodium symporter activity
KM405_07290	COG1757	Na H antiporter
KM405_07305	COG4758	membrane
KM405_07310	COG4585	Histidine kinase
KM405_07315	COG2197	response regulator
KM405_07325	COG1114	Component of the transport system for branched-chain amino acids
KM405_07335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM405_07360	COG1017	nitric oxide dioxygenase activity
KM405_07360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM405_07375	COG0730	response to heat
KM405_07380	COG0306	phosphate transporter
KM405_07385	COG1392	Phosphate transport regulator
KM405_07390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM405_07405	COG3852	Histidine kinase
KM405_07410	COG1801	Protein of unknown function DUF72
KM405_07420	COG0582	viral genome integration into host DNA
KM405_07425	COG5002	protein histidine kinase activity
KM405_07445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM405_07445	COG0392	lysyltransferase activity
KM405_07460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM405_07465	COG1686	Belongs to the peptidase S11 family
KM405_07470	COG2715	membrane protein required for spore maturation
KM405_07475	COG0700	Nucleoside recognition
KM405_07480	COG1187	pseudouridine synthase activity
KM405_07490	COG1333	cytochrome c biogenesis protein
KM405_07495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM405_07500	COG0745	RESPONSE REGULATOR receiver
KM405_07505	COG5002	protein histidine kinase activity
KM405_07510	COG2096	Adenosyltransferase
KM405_07525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM405_07530	COG1141	Ferredoxin
KM405_07535	COG4955	Helix-turn-helix domain
KM405_07540	COG0514	ATP-dependent DNA helicase (RecQ)
KM405_07545	COG1266	CAAX protease self-immunity
KM405_07565	COG4862	establishment of competence for transformation
KM405_07570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM405_07590	COG0492	ferredoxin-NADP+ reductase activity
KM405_07665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM405_07680	COG0142	geranyltranstransferase activity
KM405_07690	COG0142	geranyltranstransferase activity
KM405_07710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM405_07715	COG0457	Tetratricopeptide repeat
KM405_07735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM405_07745	COG4347	Protein of unknown function (DUF1405)
KM405_07760	COG2738	Putative neutral zinc metallopeptidase
KM405_07770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_07775	COG1694	Mazg nucleotide pyrophosphohydrolase
KM405_07790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM405_07795	COG0438	transferase activity, transferring glycosyl groups
KM405_07850	COG3935	DnaD domain protein
KM405_07855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM405_07865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM405_07865	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM405_07930	COG0116	Belongs to the methyltransferase superfamily
KM405_07940	COG1199	ATP-dependent helicase activity
KM405_07945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM405_07955	COG3173	Aminoglycoside phosphotransferase
KM405_07960	COG0024	Methionine aminopeptidase
KM405_07970	COG2233	PERMEase
KM405_07975	COG2311	Membrane
KM405_07980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM405_07990	COG0456	acetyltransferase
KM405_08040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM405_08065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM405_08080	COG1215	transferase activity, transferring glycosyl groups
KM405_08085	COG0438	transferase activity, transferring glycosyl groups
KM405_08100	COG0454	-acetyltransferase
KM405_08120	COG0328	RNA-DNA hybrid ribonuclease activity
KM405_08160	COG1280	lysine exporter protein (LysE YggA)
KM405_08175	COG3162	membrane
KM405_08180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM405_08185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM405_08195	COG0475	glutathione-regulated potassium exporter activity
KM405_08200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM405_08205	COG0789	Transcriptional regulator
KM405_08205	COG4978	Transcriptional regulator
KM405_08215	COG2323	membrane
KM405_08220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM405_08275	COG1923	regulation of RNA biosynthetic process
KM405_08285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM405_08290	COG1360	Flagellar Motor Protein
KM405_08295	COG2201	protein-glutamate methylesterase activity
KM405_08300	COG0643	Histidine kinase
KM405_08300	COG2198	Histidine kinase
KM405_08305	COG0643	Histidine kinase
KM405_08305	COG2198	Histidine kinase
KM405_08310	COG1776	CheC inhibitor of MCP methylation
KM405_08310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM405_08325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM405_08345	COG1256	bacterial-type flagellum assembly
KM405_08370	COG1815	bacterial-type flagellum-dependent cell motility
KM405_08375	COG1558	bacterial-type flagellum-dependent cell motility
KM405_08390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM405_08400	COG1157	protein secretion by the type III secretion system
KM405_08440	COG0835	chemotaxis
KM405_08440	COG0784	Response regulator, receiver
KM405_08450	COG0463	Glycosyl transferase, family 2
KM405_08485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM405_08490	COG0741	lytic transglycosylase activity
KM405_08505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM405_08505	COG1776	CheC inhibitor of MCP methylation
KM405_08515	COG1338	Plays a role in the flagellum-specific transport system
KM405_08520	COG1987	bacterial-type flagellum assembly
KM405_08530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM405_08535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM405_08540	COG1419	protein localization to endoplasmic reticulum
KM405_08545	COG4786	Flagellar basal body rod
KM405_08550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM405_08575	COG1309	transcriptional regulator
KM405_08595	COG2329	Antibiotic biosynthesis monooxygenase
KM405_08620	COG0583	DNA-binding transcription factor activity
KM405_08625	COG3842	ATPase activity
KM405_08630	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM405_08640	COG1234	tRNA 3'-trailer cleavage
KM405_08665	COG1686	Belongs to the peptidase S11 family
KM405_08675	COG0406	alpha-ribazole phosphatase activity
KM405_08705	COG0367	asparagine synthase
KM405_08735	COG1802	Transcriptional regulator
KM405_08740	COG0697	spore germination
KM405_08745	COG0523	cobalamin synthesis protein
KM405_08750	COG0701	Predicted permease
KM405_08760	COG0438	transferase activity, transferring glycosyl groups
KM405_08760	COG1216	Glycosyl transferase, family 2
KM405_08765	COG1757	Na H antiporter
KM405_08770	COG0114	fumarate hydratase activity
KM405_08795	COG3340	Belongs to the peptidase S51 family
KM405_08815	COG0785	Cytochrome C biogenesis protein
KM405_08845	COG2733	membrane
KM405_08880	COG1131	(ABC) transporter
KM405_08895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM405_08900	COG0528	UMP kinase activity
KM405_08910	COG1027	Aspartate ammonia-lyase
KM405_08915	COG0281	malic enzyme
KM405_08920	COG4191	Histidine kinase
KM405_08925	COG0784	Response regulator, receiver
KM405_08930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM405_08985	COG1051	belongs to the nudix hydrolase family
KM405_08990	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM405_09000	COG2814	Major facilitator Superfamily
KM405_09015	COG1966	Carbon starvation protein
KM405_09030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_09040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM405_09050	COG2223	nitrite transmembrane transporter activity
KM405_09055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM405_09070	COG2244	polysaccharide biosynthetic process
KM405_09075	COG0733	neurotransmitter:sodium symporter activity
KM405_09085	COG5566	PFAM Mor transcription activator
KM405_09090	COG2323	membrane
KM405_09105	COG2084	Dehydrogenase
KM405_09120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM405_09130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM405_09135	COG0028	Belongs to the TPP enzyme family
KM405_09140	COG0440	acetolactate synthase activity
KM405_09145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM405_09155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM405_09180	COG2814	Major facilitator Superfamily
KM405_09185	COG3384	dioxygenase
KM405_09195	COG3279	Response regulator of the LytR AlgR family
KM405_09200	COG0427	acetyl-CoA hydrolase
KM405_09220	COG1073	alpha beta
KM405_09250	COG0535	radical SAM domain protein
KM405_09255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_09275	COG1914	H( )-stimulated, divalent metal cation uptake system
KM405_09290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM405_09320	COG2390	Transcriptional regulator
KM405_09330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_09335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM405_09350	COG4224	UPF0291 protein
KM405_09370	COG0006	proline dipeptidase activity
KM405_09375	COG2132	Multicopper oxidase
KM405_09390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM405_09405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM405_09420	COG2372	response to copper ion
KM405_09420	COG1276	copper resistance
KM405_09425	COG4549	nuclear export factor GLE1
KM405_09435	COG0697	spore germination
KM405_09440	COG0583	DNA-binding transcription factor activity
KM405_09445	COG1959	2 iron, 2 sulfur cluster binding
KM405_09450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM405_09455	COG0778	Nitroreductase
KM405_09465	COG0628	permease
KM405_09475	COG1231	oxidoreductase activity
KM405_09480	COG0523	cobalamin synthesis protein
KM405_09495	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_09500	COG2030	dehydratase
KM405_09505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_09515	COG0411	ABC transporter
KM405_09535	COG0583	DNA-binding transcription factor activity
KM405_09545	COG1942	4-Oxalocrotonate Tautomerase
KM405_09555	COG1846	Transcriptional regulator
KM405_09565	COG1271	oxidase subunit
KM405_09570	COG1294	oxidase, subunit
KM405_09575	COG4988	ABC transporter
KM405_09580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM405_09600	COG1686	Belongs to the peptidase S11 family
KM405_09615	COG0791	NLP P60 protein
KM405_09615	COG1388	LysM domain
KM405_09630	COG0745	RESPONSE REGULATOR receiver
KM405_09635	COG5002	protein histidine kinase activity
KM405_09645	COG0300	oxidoreductase activity
KM405_09680	COG0460	homoserine dehydrogenase
KM405_09705	COG1316	TRANSCRIPTIONal
KM405_09715	COG0745	RESPONSE REGULATOR receiver
KM405_09720	COG5002	protein histidine kinase activity
KM405_09735	COG1285	pathogenesis
KM405_09740	COG1247	-acetyltransferase
KM405_09760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM405_09770	COG1082	Xylose isomerase domain protein TIM barrel
KM405_09785	COG1279	arginine transmembrane transporter activity
KM405_09795	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM405_09835	COG2002	toxin-antitoxin pair type II binding
KM405_09840	COG1404	Belongs to the peptidase S8 family
KM405_09845	COG0640	Transcriptional regulator
KM405_09850	COG0667	Aldo Keto reductase
KM405_09855	COG2814	Major facilitator Superfamily
KM405_09880	COG0840	transmembrane signaling receptor activity
KM405_09895	COG3949	Membrane
KM405_09900	COG0783	Belongs to the Dps family
KM405_09915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM405_09925	COG1231	oxidoreductase activity
KM405_09935	COG4989	oxidoreductase activity
KM405_09940	COG0523	cobalamin synthesis protein
KM405_09945	COG0456	acetyltransferase
KM405_10000	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM405_10000	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM405_10010	COG0702	epimerase
KM405_10020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM405_10030	COG4166	transmembrane transport
KM405_10045	COG0406	alpha-ribazole phosphatase activity
KM405_10055	COG5337	Spore coat protein CotH
KM405_10060	COG1051	belongs to the nudix hydrolase family
KM405_10065	COG0586	Pfam SNARE associated Golgi protein
KM405_10070	COG2244	polysaccharide biosynthetic process
KM405_10080	COG0701	Predicted permease
KM405_10085	COG3689	TIGRFAM TIGR03943 family protein
KM405_10090	COG1607	acyl-coa hydrolase
KM405_10100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM405_10115	COG0702	epimerase
KM405_10120	COG2839	Protein conserved in bacteria
KM405_10125	COG1253	flavin adenine dinucleotide binding
KM405_10140	COG1114	Component of the transport system for branched-chain amino acids
KM405_10145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM405_10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM405_10175	COG1876	peptidase activity
KM405_10185	COG0154	amidase activity
KM405_10190	COG2211	Major facilitator Superfamily
KM405_10210	COG0561	phosphatase activity
KM405_10220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM405_10225	COG4106	trans-aconitate 2-methyltransferase activity
KM405_10240	COG1819	glycosyl
KM405_10245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_10250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_10275	COG0456	acetyltransferase
KM405_10325	COG3874	Sporulation protein YtfJ
KM405_10350	COG2226	methyltransferase
KM405_10375	COG0346	lactoylglutathione lyase activity
KM405_10385	COG0604	alcohol dehydrogenase
KM405_10390	COG1595	DNA-templated transcription, initiation
KM405_10415	COG0386	Belongs to the glutathione peroxidase family
KM405_10420	COG1305	Transglutaminase-like
KM405_10425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM405_10430	COG0714	Associated with various cellular activities
KM405_10445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM405_10450	COG1140	nitrate reductase beta subunit
KM405_10455	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM405_10460	COG2181	nitrate reductase activity
KM405_10480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM405_10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM405_10490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM405_10495	COG0303	'Molybdopterin
KM405_10500	COG0314	molybdopterin synthase activity
KM405_10510	COG2223	nitrite transmembrane transporter activity
KM405_10525	COG1648	precorrin-2 dehydrogenase activity
KM405_10535	COG1587	Uroporphyrinogen-III synthase
KM405_10535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM405_10540	COG2146	nitrite reductase [NAD(P)H] activity
KM405_10545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM405_10550	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM405_10585	COG2359	stage V sporulation protein S
KM405_10600	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM405_10615	COG1418	mRNA catabolic process
KM405_10620	COG0488	(ABC) transporter
KM405_10635	COG0629	single-stranded DNA binding
KM405_10650	COG1413	lyase activity
KM405_10665	COG2136	Putative SAM-dependent methyltransferase
KM405_10665	COG2521	methyltransferase
KM405_10670	COG0018	arginyl-trna synthetase
KM405_10695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM405_10715	COG0017	Asparaginyl-tRNA synthetase
KM405_10735	COG1674	ftsk spoiiie
KM405_10805	COG1929	Belongs to the glycerate kinase type-1 family
KM405_10810	COG0471	metal ion transport
KM405_10815	COG0745	RESPONSE REGULATOR receiver
KM405_10820	COG5002	protein histidine kinase activity
KM405_10820	COG3850	Histidine kinase
KM405_10835	COG0733	neurotransmitter:sodium symporter activity
KM405_10860	COG2610	gluconate transmembrane transporter activity
KM405_10865	COG1454	alcohol dehydrogenase
KM405_10870	COG1794	racemase activity, acting on amino acids and derivatives
KM405_10880	COG0456	acetyltransferase
KM405_10895	COG1131	(ABC) transporter
KM405_10910	COG0546	phosphoglycolate phosphatase activity
KM405_10930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM405_10945	COG0768	penicillin binding
KM405_10950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM405_10955	COG0204	Acyl-transferase
KM405_10960	COG1272	protein, Hemolysin III
KM405_10970	COG0805	protein transport
KM405_10980	COG1307	EDD domain protein, DegV family
KM405_10985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM405_10990	COG1999	signal sequence binding
KM405_10995	COG0071	Belongs to the small heat shock protein (HSP20) family
KM405_11000	COG0367	asparagine synthase
KM405_11015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_11020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM405_11045	COG1051	belongs to the nudix hydrolase family
KM405_11055	COG0668	transmembrane transport
KM405_11060	COG2203	Gaf domain
KM405_11060	COG4585	Histidine kinase
KM405_11065	COG2197	response regulator
KM405_11075	COG1064	alcohol dehydrogenase
KM405_11100	COG1070	Carbohydrate kinase
KM405_11105	COG1070	Carbohydrate kinase
KM405_11135	COG1125	glycine betaine transport
KM405_11135	COG0517	IMP dehydrogenase activity
KM405_11140	COG1174	glycine betaine transport
KM405_11175	COG1253	flavin adenine dinucleotide binding
KM405_11180	COG1012	belongs to the aldehyde dehydrogenase family
KM405_11185	COG5506	Protein of unknown function (DUF1694)
KM405_11200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM405_11205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM405_11215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM405_11220	COG0456	acetyltransferase
KM405_11225	COG3829	transcription factor binding
KM405_11230	COG1509	lysine 2,3-aminomutase activity
KM405_11270	COG4326	sporulation control protein
KM405_11275	COG0671	phosphoesterase, PA-phosphatase related
KM405_11280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM405_11285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM405_11315	COG1787	Restriction endonuclease
KM405_11315	COG1715	Restriction endonuclease
KM405_11405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM405_11445	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM405_11445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM405_11450	COG2814	Major facilitator Superfamily
KM405_11455	COG4841	protein insertion into membrane
KM405_11460	COG0372	Belongs to the citrate synthase family
KM405_11465	COG2079	MmgE PrpD family protein
KM405_11470	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM405_11475	COG1960	acyl-CoA dehydrogenase activity
KM405_11480	COG2084	Dehydrogenase
KM405_11490	COG1280	lysine exporter protein (LysE YggA)
KM405_11495	COG1024	Enoyl-CoA hydratase
KM405_11510	COG0420	3'-5' exonuclease activity
KM405_11515	COG0419	ATPase involved in DNA repair
KM405_11540	COG2223	nitrite transmembrane transporter activity
KM405_11545	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_11550	COG1169	isochorismate synthase
KM405_11555	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM405_11560	COG3433	isochorismatase activity
KM405_11560	COG1535	isochorismatase
KM405_11565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM405_11570	COG3251	PFAM MbtH domain protein
KM405_11575	COG2814	Major facilitator Superfamily
KM405_11590	COG0776	regulation of translation
KM405_11600	COG2318	DinB family
KM405_11610	COG1115	amino acid carrier protein
KM405_11625	COG2329	Antibiotic biosynthesis monooxygenase
KM405_11630	COG1187	pseudouridine synthase activity
KM405_11635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM405_11650	COG0596	Alpha beta hydrolase
KM405_11655	COG2814	Major facilitator Superfamily
KM405_11675	COG2226	methyltransferase
KM405_11720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_11755	COG1247	-acetyltransferase
KM405_11785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM405_11795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_11805	COG1278	Cold shock
KM405_11820	COG0010	Belongs to the arginase family
KM405_11825	COG0561	phosphatase activity
KM405_11870	COG0583	DNA-binding transcription factor activity
KM405_11875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM405_11890	COG0583	DNA-binding transcription factor activity
KM405_11895	COG2258	MOSC domain
KM405_11910	COG1132	(ABC) transporter
KM405_11915	COG1132	(ABC) transporter
KM405_11935	COG1396	sequence-specific DNA binding
KM405_11960	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM405_11965	COG1595	DNA-templated transcription, initiation
KM405_11990	COG1649	PFAM Uncharacterised BCR, COG1649
KM405_12015	COG2971	BadF BadG BcrA BcrD
KM405_12020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM405_12025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM405_12045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_12075	COG1309	transcriptional regulator
KM405_12090	COG1136	(ABC) transporter
KM405_12090	COG0577	efflux transmembrane transporter activity
KM405_12095	COG0500	methyltransferase
KM405_12095	COG3615	Tellurite resistance protein tehB
KM405_12105	COG2226	methyltransferase
KM405_12110	COG3961	Belongs to the TPP enzyme family
KM405_12115	COG1846	Transcriptional regulator
KM405_12155	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM405_12170	COG1595	DNA-templated transcription, initiation
KM405_12180	COG0768	penicillin binding
KM405_12190	COG2367	Beta-lactamase
KM405_12195	COG0671	phosphoesterase, PA-phosphatase related
KM405_12200	COG1609	Transcriptional regulator
KM405_12205	COG2814	Major facilitator Superfamily
KM405_12210	COG0673	inositol 2-dehydrogenase activity
KM405_12220	COG1012	belongs to the aldehyde dehydrogenase family
KM405_12235	COG0191	fructose-bisphosphate aldolase activity
KM405_12240	COG3718	enzyme involved in inositol metabolism
KM405_12265	COG0457	Tetratricopeptide repeat
KM405_12270	COG1476	TRANSCRIPTIONal
KM405_12285	COG1876	peptidase activity
KM405_12305	COG1309	transcriptional regulator
KM405_12310	COG0488	(ABC) transporter
KM405_12325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_12340	COG1252	NADH dehydrogenase
KM405_12345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_12360	COG1131	(ABC) transporter
KM405_12370	COG1309	transcriptional regulator
KM405_12385	COG1960	acyl-CoA dehydrogenase activity
KM405_12390	COG0439	Biotin carboxylase
KM405_12395	COG0511	ligase activity, forming carbon-carbon bonds
KM405_12400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM405_12405	COG1024	Enoyl-CoA hydratase
KM405_12410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM405_12415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM405_12425	COG1247	-acetyltransferase
KM405_12430	COG0572	uridine kinase
KM405_12440	COG2318	DinB family
KM405_12445	COG1686	Belongs to the peptidase S11 family
KM405_12470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM405_12510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM405_12510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM405_12535	COG2814	Major facilitator Superfamily
KM405_12555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM405_12575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_12590	COG1063	alcohol dehydrogenase
KM405_12620	COG3773	Cell wall hydrolase
KM405_12630	COG0745	RESPONSE REGULATOR receiver
KM405_12645	COG0488	(ABC) transporter
KM405_12660	COG1136	(ABC) transporter
KM405_12685	COG0460	homoserine dehydrogenase
KM405_12690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_12700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM405_12765	COG2124	cytochrome p450
KM405_12800	COG0561	phosphatase activity
KM405_12810	COG5002	protein histidine kinase activity
KM405_12815	COG0768	penicillin binding
KM405_12820	COG1819	glycosyl
KM405_12825	COG1794	racemase activity, acting on amino acids and derivatives
KM405_12835	COG1122	ATPase activity
KM405_12850	COG2205	protein histidine kinase activity
KM405_12860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM405_12865	COG0604	alcohol dehydrogenase
KM405_12870	COG0768	penicillin binding
KM405_12880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM405_12915	COG0693	protein deglycase activity
KM405_12945	COG2814	Major facilitator Superfamily
KM405_12960	COG0584	glycerophosphoryl diester phosphodiesterase
KM405_12980	COG0697	spore germination
KM405_13005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM405_13015	COG2223	nitrite transmembrane transporter activity
KM405_13030	COG2816	NAD+ diphosphatase activity
KM405_13035	COG0592	DNA-directed DNA polymerase activity
KM405_13040	COG1051	belongs to the nudix hydrolase family
KM405_13075	COG3878	Protein conserved in bacteria
KM405_13120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM405_13135	COG0322	excinuclease ABC activity
KM405_13175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM405_13200	COG1011	Hydrolase
KM405_13220	COG0076	glutamate decarboxylase activity
KM405_13235	COG1523	belongs to the glycosyl hydrolase 13 family
KM405_13240	COG3227	Zinc metalloprotease (Elastase)
KM405_13260	COG0201	protein transport
KM405_13270	COG0697	spore germination
KM405_13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_13305	COG4129	membrane
KM405_13310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_13325	COG2959	enzyme of heme biosynthesis
KM405_13345	COG3483	tryptophan 2,3-dioxygenase activity
KM405_13350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM405_13355	COG3844	kynureninase activity
KM405_13360	COG1309	transcriptional regulator
KM405_13390	COG3284	Transcriptional regulator
KM405_13410	COG1349	DNA-binding transcription factor activity
KM405_13430	COG1959	2 iron, 2 sulfur cluster binding
KM405_13445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM405_13450	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM405_13455	COG0022	dehydrogenase e1 component
KM405_13460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM405_13470	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_13475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM405_13475	COG0456	acetyltransferase
KM405_13505	COG4176	ABC-type proline glycine betaine transport system permease component
KM405_13510	COG0517	IMP dehydrogenase activity
KM405_13510	COG4175	Glycine betaine
KM405_13535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM405_13540	COG2153	protein acetylation
KM405_13545	COG3397	chitin binding
KM405_13560	COG2205	protein histidine kinase activity
KM405_13585	COG0658	competence protein
KM405_13585	COG2333	competence protein COMEC
KM405_13635	COG3973	AAA domain
KM405_13650	COG2105	PFAM AIG2 family protein
KM405_13655	COG0514	ATP-dependent DNA helicase (RecQ)
KM405_13675	COG4637	Psort location Cytoplasmic, score
KM405_13700	COG3397	chitin binding
KM405_13715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM405_13720	COG1115	amino acid carrier protein
KM405_13725	COG1012	belongs to the aldehyde dehydrogenase family
KM405_13730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM405_13740	COG3938	Belongs to the proline racemase family
KM405_13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM405_13785	COG0586	Pfam SNARE associated Golgi protein
KM405_13800	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM405_13805	COG0519	Catalyzes the synthesis of GMP from XMP
KM405_13810	COG4166	transmembrane transport
KM405_13820	COG4948	Mandelate Racemase Muconate Lactonizing
KM405_13865	COG2936	dipeptidyl-peptidase activity
KM405_13870	COG5002	protein histidine kinase activity
KM405_13910	COG1164	Oligoendopeptidase f
KM405_13925	COG1307	EDD domain protein, DegV family
KM405_13945	COG2814	Major facilitator Superfamily
KM405_13955	COG1664	Polymer-forming cytoskeletal
KM405_13960	COG0789	Transcriptional regulator
KM405_13965	COG4533	DNA binding
KM405_13970	COG0477	Major facilitator Superfamily
KM405_13970	COG2814	Major facilitator Superfamily
KM405_13990	COG2261	transglycosylase associated protein
KM405_14005	COG2226	methyltransferase
KM405_14040	COG0436	Aminotransferase
KM405_14045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM405_14050	COG5146	pantothenate kinase activity
KM405_14070	COG1131	(ABC) transporter
KM405_14115	COG0628	permease
KM405_14125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM405_14130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM405_14135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM405_14140	COG1116	anion transmembrane transporter activity
KM405_14160	COG2816	NAD+ diphosphatase activity
KM405_14180	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM405_14205	COG0697	spore germination
KM405_14210	COG2318	DinB family
KM405_14230	COG4912	Dna alkylation repair
KM405_14250	COG0861	Integral membrane protein TerC family
KM405_14255	COG1368	sulfuric ester hydrolase activity
KM405_14260	COG0488	(ABC) transporter
KM405_14270	COG2409	Drug exporters of the RND superfamily
KM405_14270	COG1033	growth of symbiont in host cell
KM405_14275	COG1033	growth of symbiont in host cell
KM405_14275	COG2409	Drug exporters of the RND superfamily
KM405_14280	COG1033	growth of symbiont in host cell
KM405_14280	COG2409	Drug exporters of the RND superfamily
KM405_14285	COG1309	transcriptional regulator
KM405_14300	COG0287	Prephenate dehydrogenase
KM405_14305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM405_14310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM405_14315	COG1605	Chorismate mutase
KM405_14315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM405_14350	COG3584	3D domain protein
KM405_14350	COG1388	LysM domain
KM405_14360	COG1595	DNA-templated transcription, initiation
KM405_14385	COG1879	ABC-type sugar transport system periplasmic component
KM405_14395	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM405_14405	COG2390	Transcriptional regulator
KM405_14410	COG1070	Carbohydrate kinase
KM405_14440	COG2329	Antibiotic biosynthesis monooxygenase
KM405_14460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_14470	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM405_14475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM405_14480	COG4187	Peptidase family M20/M25/M40
KM405_14485	COG1414	Transcriptional regulator
KM405_14490	COG0833	amino acid
KM405_14495	COG1690	Belongs to the RtcB family
KM405_14500	COG3239	Fatty acid desaturase
KM405_14505	COG1785	Belongs to the alkaline phosphatase family
KM405_14515	COG3655	Transcriptional regulator
KM405_14530	COG4377	Putative membrane peptidase family (DUF2324)
KM405_14540	COG3279	Response regulator of the LytR AlgR family
KM405_14550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_14555	COG0346	lactoylglutathione lyase activity
KM405_14575	COG0714	Associated with various cellular activities
KM405_14600	COG0463	Glycosyl transferase, family 2
KM405_14625	COG0463	Glycosyl transferase, family 2
KM405_14635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM405_14640	COG0753	catalase activity
KM405_14650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM405_14675	COG0714	Associated with various cellular activities
KM405_14685	COG0778	Nitroreductase
KM405_14690	COG1846	Transcriptional regulator
KM405_14725	COG1725	Transcriptional regulator
KM405_14735	COG0577	efflux transmembrane transporter activity
KM405_14735	COG1136	(ABC) transporter
KM405_14760	COG2207	Transcriptional regulator
KM405_14765	COG0456	acetyltransferase
KM405_14785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_14805	COG0642	Histidine kinase
KM405_14810	COG0745	RESPONSE REGULATOR receiver
KM405_14815	COG0596	Alpha beta hydrolase
KM405_14845	COG0730	response to heat
KM405_14855	COG0833	amino acid
KM405_14865	COG4335	DNA alkylation repair
KM405_14905	COG0768	penicillin binding
KM405_14915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM405_14945	COG1984	allophanate hydrolase subunit 2
KM405_14950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM405_14955	COG1414	Transcriptional regulator
KM405_14970	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM405_14975	COG0640	Transcriptional regulator
KM405_14985	COG1960	acyl-CoA dehydrogenase activity
KM405_15005	COG3314	Sporulation integral membrane protein YlbJ
KM405_15020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM405_15035	COG0574	Belongs to the PEP-utilizing enzyme family
KM405_15035	COG3848	Pyruvate phosphate dikinase
KM405_15040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_15055	COG5577	PFAM Coat F domain
KM405_15060	COG3403	YqcI/YcgG family
KM405_15065	COG1280	lysine exporter protein (LysE YggA)
KM405_15100	COG1063	alcohol dehydrogenase
KM405_15115	COG1027	Aspartate ammonia-lyase
KM405_15120	COG0252	asparaginase activity
KM405_15125	COG1396	sequence-specific DNA binding
KM405_15135	COG0322	excinuclease ABC activity
KM405_15140	COG0531	amino acid
KM405_15145	COG1114	Component of the transport system for branched-chain amino acids
KM405_15150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM405_15160	COG0281	malic enzyme
KM405_15175	COG0531	amino acid
KM405_15185	COG0784	Response regulator, receiver
KM405_15195	COG2066	Belongs to the glutaminase family
KM405_15200	COG1115	amino acid carrier protein
KM405_15230	COG0737	Belongs to the 5'-nucleotidase family
KM405_15235	COG0753	catalase activity
KM405_15240	COG2267	carboxylic ester hydrolase activity
KM405_15245	COG1335	isochorismatase
KM405_15265	COG0583	DNA-binding transcription factor activity
KM405_15270	COG1846	Transcriptional regulator
KM405_15310	COG0415	Belongs to the DNA photolyase family
KM405_15315	COG0288	reversible hydration of carbon dioxide
KM405_15325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM405_15330	COG5609	conserved protein (DUF2294)
KM405_15345	COG1575	Belongs to the MenA family. Type 1 subfamily
KM405_15350	COG2267	carboxylic ester hydrolase activity
KM405_15355	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM405_15360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM405_15365	COG1121	(ABC) transporter
KM405_15395	COG0798	PFAM Bile acid sodium symporter
KM405_15400	COG0346	lactoylglutathione lyase activity
KM405_15405	COG0640	Transcriptional regulator
KM405_15420	COG0443	Heat shock 70 kDa protein
KM405_15435	COG1522	sequence-specific DNA binding
KM405_15450	COG0346	lactoylglutathione lyase activity
KM405_15475	COG2169	Transcriptional regulator
KM405_15520	COG2814	Major facilitator Superfamily
KM405_15545	COG0745	RESPONSE REGULATOR receiver
KM405_15550	COG3850	Histidine kinase
KM405_15550	COG5002	protein histidine kinase activity
KM405_15575	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM405_15595	COG1476	TRANSCRIPTIONal
KM405_15610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_15615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM405_15625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_15630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM405_15645	COG1136	(ABC) transporter
KM405_15650	COG0577	efflux transmembrane transporter activity
KM405_15665	COG5002	protein histidine kinase activity
KM405_15665	COG3850	Histidine kinase
KM405_15675	COG2364	Membrane
KM405_15680	COG1846	Transcriptional regulator
KM405_15690	COG2808	Putative FMN-binding domain
KM405_15695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_15700	COG2271	Major facilitator Superfamily
KM405_15705	COG1556	Lactate utilization protein
KM405_15710	COG1139	Iron-sulfur cluster binding protein
KM405_15720	COG0583	DNA-binding transcription factor activity
KM405_15730	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM405_15755	COG0738	Major facilitator superfamily
KM405_15760	COG0673	inositol 2-dehydrogenase activity
KM405_15765	COG0561	phosphatase activity
KM405_15775	COG1609	Transcriptional regulator
KM405_15780	COG0457	Tetratricopeptide repeat
KM405_15800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM405_15830	COG0534	Mate efflux family protein
KM405_15850	COG2814	Major facilitator Superfamily
KM405_15855	COG1309	transcriptional regulator
KM405_15870	COG0814	amino acid
KM405_15875	COG1760	l-serine dehydratase
KM405_15880	COG1760	l-serine dehydratase
KM405_15890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM405_15895	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM405_15905	COG1335	isochorismatase
KM405_15910	COG1522	sequence-specific DNA binding
KM405_15915	COG0531	amino acid
KM405_15930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM405_15950	COG1595	DNA-templated transcription, initiation
KM405_15965	COG0662	Cupin 2, conserved barrel domain protein
KM405_15970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_15970	COG2207	Transcriptional regulator
KM405_16020	COG0477	Major facilitator Superfamily
KM405_16030	COG1846	Transcriptional regulator
KM405_16035	COG2814	Major facilitator Superfamily
KM405_16045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM405_16050	COG1131	(ABC) transporter
KM405_16070	COG2076	Multidrug Resistance protein
KM405_16075	COG1309	transcriptional regulator
KM405_16085	COG2031	fatty acid transporter
KM405_16095	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM405_16125	COG1122	ATPase activity
KM405_16130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM405_16145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM405_16150	COG1288	antiporter activity
KM405_16155	COG2356	endonuclease I
KM405_16170	COG3620	sequence-specific DNA binding
KM405_16175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM405_16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM405_16185	COG0124	histidyl-tRNA synthetase
KM405_16200	COG1733	regulation of RNA biosynthetic process
KM405_16205	COG0778	Nitroreductase
KM405_16225	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_16235	COG1131	(ABC) transporter
KM405_16260	COG1011	Hydrolase
KM405_16270	COG2365	Tyrosine phosphatase family
KM405_16295	COG0346	lactoylglutathione lyase activity
KM405_16300	COG1940	carbohydrate kinase activity
KM405_16305	COG0738	Major facilitator superfamily
KM405_16310	COG0110	maltose O-acetyltransferase activity
KM405_16320	COG0577	efflux transmembrane transporter activity
KM405_16320	COG1136	(ABC) transporter
KM405_16335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM405_16340	COG0628	permease
KM405_16360	COG2226	methyltransferase
KM405_16370	COG0477	Major facilitator Superfamily
KM405_16400	COG1253	flavin adenine dinucleotide binding
KM405_16405	COG0789	Transcriptional regulator
KM405_16410	COG0697	spore germination
KM405_16415	COG1357	PFAM Pentapeptide repeats (8 copies)
KM405_16420	COG3813	Protein conserved in bacteria
KM405_16425	COG2706	6-phosphogluconolactonase activity
KM405_16430	COG1070	Carbohydrate kinase
KM405_16440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM405_16445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM405_16455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM405_16460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM405_16465	COG0604	alcohol dehydrogenase
KM405_16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM405_16480	COG0604	alcohol dehydrogenase
KM405_16480	COG3321	synthase
KM405_16485	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_16510	COG0656	L-ascorbic acid biosynthetic process
KM405_16515	COG2814	Major facilitator Superfamily
KM405_16530	COG0346	lactoylglutathione lyase activity
KM405_16535	COG0814	amino acid
KM405_16560	COG1393	Belongs to the ArsC family
KM405_16565	COG1733	regulation of RNA biosynthetic process
KM405_16570	COG2188	Transcriptional regulator
KM405_16580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM405_16585	COG1733	regulation of RNA biosynthetic process
KM405_16590	COG1733	regulation of RNA biosynthetic process
KM405_16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_16625	COG0384	phenazine biosynthesis protein PhzF
KM405_16635	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_16645	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_16655	COG1733	regulation of RNA biosynthetic process
KM405_16690	COG1191	sigma factor activity
KM405_16705	COG1309	transcriptional regulator
KM405_16725	COG3152	Membrane
KM405_16750	COG1151	hydroxylamine reductase activity
KM405_16760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_16765	COG3757	hydrolase, family 25
KM405_16765	COG3409	Peptidoglycan-binding domain 1 protein
KM405_16800	COG2072	flavoprotein involved in K transport
KM405_16835	COG0604	alcohol dehydrogenase
KM405_16840	COG1113	amino acid transport
KM405_16845	COG2814	Major facilitator Superfamily
KM405_16875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM405_16880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM405_16900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_16915	COG3739	integral membrane protein
KM405_16920	COG0384	phenazine biosynthesis protein PhzF
KM405_16950	COG0583	DNA-binding transcription factor activity
KM405_16970	COG1193	negative regulation of DNA recombination
KM405_16995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM405_17025	COG0584	glycerophosphoryl diester phosphodiesterase
KM405_17050	COG0640	Transcriptional regulator
KM405_17055	COG0604	alcohol dehydrogenase
KM405_17075	COG2808	Putative FMN-binding domain
KM405_17080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM405_17090	COG0385	Bile acid
KM405_17095	COG0277	FAD linked oxidase domain protein
KM405_17125	COG1216	Glycosyl transferase, family 2
KM405_17130	COG1024	Enoyl-CoA hydratase
KM405_17140	COG1285	pathogenesis
KM405_17155	COG2514	catechol 2,3-dioxygenase activity
KM405_17160	COG2720	vancomycin resistance protein
KM405_17200	COG0716	FMN binding
KM405_17230	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_17240	COG0165	Argininosuccinate lyase
KM405_17255	COG4145	pantothenate transmembrane transporter activity
KM405_17265	COG1012	belongs to the aldehyde dehydrogenase family
KM405_17270	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_17280	COG1657	PFAM Prenyltransferase squalene oxidase
KM405_17285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM405_17290	COG2962	Rard protein
KM405_17295	COG3326	Membrane
KM405_17310	COG0489	protein tyrosine kinase activity
KM405_17320	COG0314	molybdopterin synthase activity
KM405_17325	COG0303	'Molybdopterin
KM405_17330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM405_17335	COG2116	formate transmembrane transporter activity
KM405_17345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM405_17350	COG5609	conserved protein (DUF2294)
KM405_17355	COG2427	Protein of unknown function (DUF1641)
KM405_17360	COG3383	formate dehydrogenase (NAD+) activity
KM405_17365	COG0697	spore germination
KM405_17405	COG2226	methyltransferase
KM405_17410	COG4166	transmembrane transport
KM405_17415	COG4166	transmembrane transport
KM405_17420	COG4166	transmembrane transport
KM405_17425	COG1301	dicarboxylic acid transport
KM405_17430	COG1316	TRANSCRIPTIONal
KM405_17440	COG1595	DNA-templated transcription, initiation
KM405_17460	COG1131	(ABC) transporter
KM405_17470	COG0673	inositol 2-dehydrogenase activity
KM405_17475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM405_17480	COG0187	DNA topoisomerase II activity
KM405_17485	COG1832	CoA-binding protein
KM405_17490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM405_17495	COG0745	RESPONSE REGULATOR receiver
KM405_17510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM405_17515	COG4841	protein insertion into membrane
KM405_17520	COG0824	Thioesterase
KM405_17550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM405_17560	COG2274	protein secretion by the type I secretion system
KM405_17565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM405_17605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM405_17620	COG0183	Belongs to the thiolase family
KM405_17625	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_17630	COG1268	BioY protein
KM405_17635	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_17685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_17695	COG5002	protein histidine kinase activity
KM405_17700	COG0400	carboxylic ester hydrolase activity
KM405_17705	COG0346	lactoylglutathione lyase activity
KM405_17710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM405_17715	COG0069	glutamate synthase activity
KM405_17720	COG1902	pentaerythritol trinitrate reductase activity
KM405_17725	COG1329	Transcriptional regulator
KM405_17730	COG0010	Belongs to the arginase family
KM405_17755	COG2226	methyltransferase
KM405_17810	COG4846	Membrane protein involved in cytochrome C biogenesis
KM405_17815	COG0785	Cytochrome C biogenesis protein
KM405_17825	COG0583	DNA-binding transcription factor activity
KM405_17830	COG1380	Effector of murein hydrolase LrgA
KM405_17835	COG1346	cytolysis
KM405_17860	COG3409	Peptidoglycan-binding domain 1 protein
KM405_17860	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM405_17875	COG1132	(ABC) transporter
KM405_17880	COG1132	(ABC) transporter
KM405_17910	COG3639	organic phosphonate transmembrane transporter activity
KM405_17915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM405_17935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM405_17955	COG1695	Transcriptional regulator
KM405_17995	COG3409	Peptidoglycan-binding domain 1 protein
KM405_17995	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM405_17995	COG1388	LysM domain
KM405_18000	COG4824	toxin secretion phage lysis holin
KM405_18155	COG1595	DNA-templated transcription, initiation
KM405_18200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM405_18285	COG1396	sequence-specific DNA binding
KM405_18310	COG0174	glutamine synthetase
KM405_18315	COG0789	Transcriptional regulator
KM405_18320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM405_18330	COG2860	membrane
KM405_18340	COG0464	growth
KM405_18370	COG3584	3D domain protein
KM405_18370	COG1388	LysM domain
KM405_18375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM405_18375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM405_18375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM405_18380	COG1105	Belongs to the carbohydrate kinase PfkB family
KM405_18385	COG1349	DNA-binding transcription factor activity
KM405_18395	COG2322	membrane
KM405_18405	COG1113	amino acid transport
KM405_18420	COG1408	metallophosphoesterase
KM405_18425	COG2116	formate transmembrane transporter activity
KM405_18435	COG2217	Heavy metal translocating P-type atpase
KM405_18440	COG2608	mercury ion transmembrane transporter activity
KM405_18445	COG1937	Protein conserved in bacteria
KM405_18455	COG2819	hydrolase of the alpha beta superfamily
KM405_18460	COG1120	ATPase activity
KM405_18465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_18470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_18480	COG0708	Exodeoxyribonuclease III
KM405_18485	COG2169	Transcriptional regulator
KM405_18490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM405_18495	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM405_18505	COG2364	Membrane
KM405_18520	COG2267	carboxylic ester hydrolase activity
KM405_18525	COG0346	lactoylglutathione lyase activity
KM405_18530	COG5001	Diguanylate cyclase
KM405_18530	COG3300	MHYT domain
KM405_18545	COG1346	cytolysis
KM405_18550	COG1380	Effector of murein hydrolase LrgA
KM405_18555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM405_18560	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM405_18560	COG0596	Alpha beta hydrolase
KM405_18565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM405_18585	COG1404	Belongs to the peptidase S8 family
KM405_18590	COG3773	Cell wall hydrolase
KM405_18595	COG0562	UDP-galactopyranose mutase
KM405_18600	COG1368	sulfuric ester hydrolase activity
KM405_18605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM405_18615	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM405_18640	COG1131	(ABC) transporter
KM405_18660	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM405_18665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM405_18670	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM405_18675	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM405_18675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM405_18685	COG2359	stage V sporulation protein S
KM405_18690	COG1692	metallophosphoesterase
KM405_18715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM405_18720	COG1426	Protein conserved in bacteria
KM405_18735	COG0300	oxidoreductase activity
KM405_18740	COG0612	Peptidase, M16
KM405_18745	COG0612	Peptidase, M16
KM405_18750	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM405_18760	COG3845	ABC transporter
KM405_18765	COG1744	ABC transporter substrate-binding protein PnrA-like
KM405_18770	COG2188	Transcriptional regulator
KM405_18775	COG1674	ftsk spoiiie
KM405_18785	COG0740	serine-type endopeptidase activity
KM405_18790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM405_18800	COG0527	aspartate kinase activity
KM405_18805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM405_18810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM405_18815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM405_18820	COG1873	PFAM PRC-barrel domain
KM405_18825	COG0612	Peptidase, M16
KM405_18830	COG0726	polysaccharide deacetylase
KM405_18845	COG0196	riboflavin kinase activity
KM405_18850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM405_18860	COG1550	Protein conserved in bacteria
KM405_18870	COG1358	cellular component organization or biogenesis
KM405_18875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM405_18880	COG0195	Participates in both transcription termination and antitermination
KM405_18900	COG0750	zinc metalloprotease
KM405_18910	COG4589	Belongs to the CDS family
KM405_18915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM405_18925	COG0528	UMP kinase activity
KM405_18955	COG4974	Belongs to the 'phage' integrase family
KM405_18965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM405_18975	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM405_19015	COG1837	Belongs to the UPF0109 family
KM405_19025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM405_19035	COG0552	protein localization to endoplasmic reticulum
KM405_19040	COG1196	nuclear chromosome segregation
KM405_19050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM405_19055	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_19060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM405_19075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM405_19080	COG1461	Dihydroxyacetone kinase
KM405_19085	COG1302	Protein conserved in bacteria
KM405_19100	COG1564	THIamine pyrophosphokinase
KM405_19105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM405_19110	COG1162	GTPase activity
KM405_19115	COG2815	serine threonine protein kinase
KM405_19115	COG0515	serine threonine protein kinase
KM405_19120	COG0631	protein serine/threonine phosphatase activity
KM405_19130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM405_19130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM405_19140	COG0242	peptide deformylase activity
KM405_19145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM405_19150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM405_19170	COG1561	YicC-like family, N-terminal region
KM405_19175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM405_19185	COG0006	proline dipeptidase activity
KM405_19200	COG3069	C4-dicarboxylate transmembrane transporter activity
KM405_19265	COG0564	pseudouridine synthase activity
KM405_19285	COG3599	regulation of cell shape
KM405_19290	COG2302	S4 RNA-binding domain
KM405_19295	COG0762	integral membrane protein
KM405_19305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM405_19310	COG1496	oxidoreductase activity
KM405_19315	COG1873	PFAM PRC-barrel domain
KM405_19320	COG1191	sigma factor activity
KM405_19325	COG1191	sigma factor activity
KM405_19335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM405_19340	COG0849	cell division
KM405_19345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM405_19350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM405_19360	COG0772	Belongs to the SEDS family
KM405_19375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM405_19380	COG0768	penicillin binding
KM405_19385	COG0768	penicillin binding
KM405_19390	COG4839	cell division protein FtsL
KM405_19405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM405_19420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM405_19425	COG1399	metal-binding, possibly nucleic acid-binding protein
KM405_19475	COG4824	toxin secretion phage lysis holin
KM405_19560	COG4626	Terminase
KM405_19560	COG1802	Transcriptional regulator
KM405_19650	COG0756	dUTP diphosphatase activity
KM405_19665	COG1191	sigma factor activity
KM405_19690	COG1484	DNA-dependent DNA replication
KM405_19720	COG1396	sequence-specific DNA binding
KM405_19735	COG1396	sequence-specific DNA binding
KM405_19750	COG0582	viral genome integration into host DNA
KM405_19760	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM405_19765	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM405_19770	COG3314	Sporulation integral membrane protein YlbJ
KM405_19780	COG0742	ribosomal rna small subunit methyltransferase
KM405_19795	COG3679	Belongs to the UPF0342 family
KM405_19800	COG0406	alpha-ribazole phosphatase activity
KM405_19815	COG2340	Cysteine-rich secretory protein family
KM405_19830	COG3336	cytochrome c oxidase
KM405_19865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM405_19870	COG0772	Belongs to the SEDS family
KM405_19880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM405_19885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM405_19895	COG4896	Protein conserved in bacteria
KM405_19910	COG1217	gtp-binding protein TYPA
KM405_19920	COG0483	inositol monophosphate 1-phosphatase activity
KM405_19940	COG1982	Orn Lys Arg decarboxylase major
KM405_19985	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM405_19990	COG0022	dehydrogenase e1 component
KM405_19995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM405_20005	COG0242	peptide deformylase activity
KM405_20010	COG0561	phosphatase activity
KM405_20020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM405_20025	COG0569	domain protein
KM405_20045	COG0583	DNA-binding transcription factor activity
KM405_20050	COG0517	IMP dehydrogenase activity
KM405_20060	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM405_20070	COG4703	Protein of unknown function (DUF1797)
KM405_20085	COG2200	EAL domain
KM405_20090	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_20095	COG1408	metallophosphoesterase
KM405_20105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM405_20140	COG2814	Major facilitator Superfamily
KM405_20160	COG3209	COG3209 Rhs family protein
KM405_20170	COG2205	protein histidine kinase activity
KM405_20180	COG0436	Aminotransferase
KM405_20185	COG1609	Transcriptional regulator
KM405_20190	COG3833	ABC-type maltose transport systems, permease component
KM405_20195	COG1175	transmembrane transport
KM405_20200	COG2182	Extracellular solute-binding protein
KM405_20210	COG0366	Alpha amylase catalytic
KM405_20215	COG3842	ATPase activity
KM405_20255	COG0183	Belongs to the thiolase family
KM405_20290	COG1695	Transcriptional regulator
KM405_20295	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_20305	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM405_20315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM405_20320	COG0436	Aminotransferase
KM405_20340	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM405_20360	COG2199	diguanylate cyclase activity
KM405_20365	COG0778	Nitroreductase
KM405_20390	COG2190	(PTS) system
KM405_20390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM405_20390	COG1263	PTS System
KM405_20395	COG3711	transcriptional antiterminator
KM405_20405	COG2188	Transcriptional regulator
KM405_20415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM405_20440	COG1547	Domain of unknown function (DUF309)
KM405_20445	COG0456	acetyltransferase
KM405_20450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM405_20455	COG4086	secreted protein
KM405_20460	COG0561	phosphatase activity
KM405_20465	COG0697	spore germination
KM405_20480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_20505	COG0733	neurotransmitter:sodium symporter activity
KM405_20525	COG1686	Belongs to the peptidase S11 family
KM405_20530	COG1725	Transcriptional regulator
KM405_20535	COG1131	(ABC) transporter
KM405_20550	COG1846	Transcriptional regulator
KM405_20565	COG0598	Magnesium transport protein CorA
KM405_20590	COG4974	Belongs to the 'phage' integrase family
KM405_20600	COG0735	belongs to the Fur family
KM405_20605	COG1300	Membrane
KM405_20625	COG0667	Aldo Keto reductase
KM405_20630	COG0656	L-ascorbic acid biosynthetic process
KM405_20635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM405_20635	COG0456	acetyltransferase
KM405_20645	COG1525	nuclease
KM405_20645	COG0737	Belongs to the 5'-nucleotidase family
KM405_20645	COG4085	toxin activity
KM405_20655	COG0596	Alpha beta hydrolase
KM405_20660	COG2056	Na+-H+ antiporter family
KM405_20665	COG1609	Transcriptional regulator
KM405_20670	COG0456	acetyltransferase
KM405_20675	COG1073	alpha beta
KM405_20690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM405_20690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM405_20695	COG0307	riboflavin synthase, alpha
KM405_20720	COG4106	trans-aconitate 2-methyltransferase activity
KM405_20725	COG1073	alpha beta
KM405_20725	COG2226	methyltransferase
KM405_20740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM405_20750	COG1757	Na H antiporter
KM405_20755	COG0737	Belongs to the 5'-nucleotidase family
KM405_20765	COG1522	sequence-specific DNA binding
KM405_20785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM405_20795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM405_20810	COG0300	oxidoreductase activity
KM405_20820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM405_20825	COG1760	l-serine dehydratase
KM405_20830	COG1760	l-serine dehydratase
KM405_20850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM405_20860	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM405_20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_20880	COG1376	ErfK ybiS ycfS ynhG family protein
KM405_20885	COG4129	membrane
KM405_20890	COG1126	abc transporter atp-binding protein
KM405_20895	COG0765	amino acid transport
KM405_20900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM405_20920	COG0772	Belongs to the SEDS family
KM405_20925	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM405_20930	COG0022	dehydrogenase e1 component
KM405_20935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM405_20940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM405_20955	COG0280	phosphate acetyltransferase
KM405_20960	COG3829	transcription factor binding
KM405_20960	COG3290	protein histidine kinase activity
KM405_20970	COG0584	glycerophosphoryl diester phosphodiesterase
KM405_20975	COG3093	addiction module antidote protein HigA
KM405_20985	COG0745	RESPONSE REGULATOR receiver
KM405_20990	COG0750	zinc metalloprotease
KM405_20995	COG0497	DNA recombination
KM405_21005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM405_21015	COG0142	geranyltranstransferase activity
KM405_21040	COG1302	Protein conserved in bacteria
KM405_21045	COG0439	Biotin carboxylase
KM405_21050	COG0511	ligase activity, forming carbon-carbon bonds
KM405_21095	COG3854	ATPases associated with a variety of cellular activities
KM405_21120	COG0006	proline dipeptidase activity
KM405_21135	COG3872	metal-dependent enzyme
KM405_21145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM405_21165	COG0095	Lipoate-protein ligase
KM405_21170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_21175	COG1609	Transcriptional regulator
KM405_21185	COG2076	Multidrug Resistance protein
KM405_21190	COG2076	Multidrug Resistance protein
KM405_21225	COG1131	(ABC) transporter
KM405_21230	COG1725	Transcriptional regulator
KM405_21260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM405_21315	COG4970	Tfp pilus assembly protein FimT
KM405_21325	COG1459	type II secretion system
KM405_21330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM405_21380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM405_21385	COG0646	methionine synthase
KM405_21385	COG1410	methionine synthase
KM405_21390	COG0646	methionine synthase
KM405_21390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM405_21395	COG0626	cystathionine gamma-synthase activity
KM405_21400	COG0626	cystathionine gamma-synthase activity
KM405_21420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_21430	COG1940	carbohydrate kinase activity
KM405_21435	COG4483	Protein conserved in bacteria
KM405_21440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM405_21445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM405_21450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM405_21455	COG0704	Plays a role in the regulation of phosphate uptake
KM405_21465	COG0581	inorganic phosphate transmembrane transporter activity
KM405_21470	COG0573	inorganic phosphate transmembrane transporter activity
KM405_21475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM405_21480	COG0768	penicillin binding
KM405_21485	COG0477	Major facilitator Superfamily
KM405_21490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM405_21515	COG0735	belongs to the Fur family
KM405_21520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM405_21525	COG1121	(ABC) transporter
KM405_21530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_21560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM405_21565	COG2384	SAM-dependent methyltransferase
KM405_21570	COG2010	Cytochrome c
KM405_21575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM405_21580	COG0358	DNA primase activity
KM405_21590	COG0517	IMP dehydrogenase activity
KM405_21605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM405_21610	COG0295	cytidine deaminase activity
KM405_21615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM405_21625	COG1480	7TM receptor with intracellular HD hydrolase
KM405_21630	COG1702	phosphate starvation-inducible protein PhoH
KM405_21645	COG1610	YqeY-like protein
KM405_21650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM405_21655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM405_21660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM405_21690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM405_21695	COG1733	regulation of RNA biosynthetic process
KM405_21720	COG1466	dna polymerase III delta subunit
KM405_21730	COG2333	competence protein COMEC
KM405_21730	COG0658	competence protein
KM405_21735	COG2131	deaminase
KM405_21740	COG1555	photosystem II stabilization
KM405_21740	COG1596	polysaccharide export
KM405_21745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM405_21750	COG2226	methyltransferase
KM405_21755	COG0799	negative regulation of ribosome biogenesis
KM405_21760	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM405_21770	COG1534	Rna-binding protein
KM405_21780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM405_21785	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM405_21810	COG1595	DNA-templated transcription, initiation
KM405_21820	COG0778	Nitroreductase
KM405_21825	COG2357	RelA SpoT domain protein
KM405_21835	COG1785	Belongs to the alkaline phosphatase family
KM405_21845	COG2267	carboxylic ester hydrolase activity
KM405_21880	COG1404	Belongs to the peptidase S8 family
KM405_21885	COG3186	Phenylalanine-4-hydroxylase
KM405_21900	COG2259	Doxx family
KM405_21940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_21950	COG1012	belongs to the aldehyde dehydrogenase family
KM405_21950	COG1454	alcohol dehydrogenase
KM405_21955	COG0626	cystathionine gamma-synthase activity
KM405_21960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM405_21985	COG0768	penicillin binding
KM405_22000	COG0826	peptidase U32
KM405_22005	COG0826	peptidase U32
KM405_22010	COG4122	O-methyltransferase activity
KM405_22015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM405_22035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM405_22045	COG0628	permease
KM405_22065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM405_22075	COG0482	sulfurtransferase activity
KM405_22080	COG1104	cysteine desulfurase activity
KM405_22085	COG1959	2 iron, 2 sulfur cluster binding
KM405_22090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM405_22100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM405_22125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM405_22135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM405_22135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM405_22140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM405_22145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM405_22145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM405_22155	COG2244	polysaccharide biosynthetic process
KM405_22160	COG2323	membrane
KM405_22170	COG1862	Preprotein translocase
KM405_22200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM405_22210	COG0697	spore germination
KM405_22215	COG0697	spore germination
KM405_22220	COG0640	Transcriptional regulator
KM405_22245	COG0157	Belongs to the NadC ModD family
KM405_22250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM405_22255	COG1104	cysteine desulfurase activity
KM405_22260	COG1827	regulation of RNA biosynthetic process
KM405_22265	COG2258	MOSC domain
KM405_22270	COG0077	Prephenate dehydratase
KM405_22275	COG0577	efflux transmembrane transporter activity
KM405_22280	COG0577	efflux transmembrane transporter activity
KM405_22285	COG1136	(ABC) transporter
KM405_22295	COG0745	RESPONSE REGULATOR receiver
KM405_22300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM405_22305	COG3290	protein histidine kinase activity
KM405_22315	COG2868	ribosomal protein
KM405_22325	COG1530	ribonuclease E activity
KM405_22330	COG1994	Peptidase M50
KM405_22335	COG0739	heme binding
KM405_22340	COG2894	cell division
KM405_22360	COG1077	Cell shape determining protein MreB Mrl
KM405_22380	COG0285	dihydrofolate synthase activity
KM405_22385	COG0525	valine-tRNA ligase activity
KM405_22395	COG1388	LysM domain
KM405_22405	COG0113	porphobilinogen synthase activity
KM405_22410	COG1587	Uroporphyrinogen-III synthase
KM405_22420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM405_22430	COG1846	Transcriptional regulator
KM405_22435	COG1764	response to oxidative stress
KM405_22450	COG1067	ATP-dependent peptidase activity
KM405_22450	COG0470	DNA polymerase III
KM405_22495	COG0622	Phosphoesterase
KM405_22510	COG5401	PFAM Sporulation and spore germination
KM405_22530	COG1309	transcriptional regulator
KM405_22545	COG2197	response regulator
KM405_22550	COG2233	PERMEase
KM405_22560	COG0402	S-adenosylhomocysteine deaminase activity
KM405_22565	COG0402	S-adenosylhomocysteine deaminase activity
KM405_22575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM405_22585	COG0444	Belongs to the ABC transporter superfamily
KM405_22590	COG4608	Belongs to the ABC transporter superfamily
KM405_22595	COG3275	phosphorelay sensor kinase activity
KM405_22600	COG3279	Response regulator of the LytR AlgR family
KM405_22615	COG1983	PspC domain protein
KM405_22620	COG1396	sequence-specific DNA binding
KM405_22625	COG0697	spore germination
KM405_22635	COG1959	2 iron, 2 sulfur cluster binding
KM405_22640	COG1668	transmembrane transport
KM405_22645	COG4152	abc transporter atp-binding protein
KM405_22650	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM405_22660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM405_22665	COG1876	peptidase activity
KM405_22670	COG0824	Thioesterase
KM405_22675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM405_22680	COG1053	succinate dehydrogenase
KM405_22685	COG2009	succinate dehydrogenase
KM405_22690	COG1719	4-vinyl reductase, 4VR
KM405_22700	COG3118	belongs to the thioredoxin family
KM405_22705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM405_22710	COG2086	electron transfer activity
KM405_22715	COG1024	Enoyl-CoA hydratase
KM405_22720	COG1309	transcriptional regulator
KM405_22725	COG0318	PFAM AMP-dependent synthetase and ligase
KM405_22745	COG2318	DinB family
KM405_22775	COG1131	(ABC) transporter
KM405_22780	COG2205	protein histidine kinase activity
KM405_22785	COG0745	RESPONSE REGULATOR receiver
KM405_22795	COG4895	conserved protein (DUF2196)
KM405_22800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM405_22815	COG4509	Sortase family
KM405_22820	COG1120	ATPase activity
KM405_22835	COG5386	Cell surface protein
KM405_22845	COG5386	Cell surface protein
KM405_22850	COG1114	Component of the transport system for branched-chain amino acids
KM405_22855	COG1187	pseudouridine synthase activity
KM405_22865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM405_22865	COG1796	DNA polymerase
KM405_22870	COG1286	toxin biosynthetic process
KM405_22915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM405_22925	COG1418	mRNA catabolic process
KM405_22950	COG2814	Major facilitator Superfamily
KM405_22955	COG1566	PFAM secretion protein HlyD family protein
KM405_22960	COG1309	transcriptional regulator
KM405_22965	COG1363	Peptidase, m42
KM405_22990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM405_23000	COG1484	DNA-dependent DNA replication
KM405_23005	COG3611	Membrane attachment protein
KM405_23015	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM405_23020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM405_23025	COG0237	dephospho-CoA kinase activity
KM405_23030	COG1971	Probably functions as a manganese efflux pump
KM405_23040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM405_23040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM405_23045	COG5002	protein histidine kinase activity
KM405_23050	COG0745	RESPONSE REGULATOR receiver
KM405_23070	COG0538	isocitrate dehydrogenase activity
KM405_23075	COG0372	Belongs to the citrate synthase family
KM405_23085	COG0628	permease
KM405_23090	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM405_23115	COG1725	Transcriptional regulator
KM405_23120	COG0281	malic enzyme
KM405_23125	COG0587	DNA-directed DNA polymerase activity
KM405_23140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM405_23160	COG4109	DRTGG domain
KM405_23175	COG0006	proline dipeptidase activity
KM405_23210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_23215	COG0662	Cupin 2, conserved barrel domain protein
KM405_23225	COG1476	TRANSCRIPTIONal
KM405_23240	COG1028	Short-chain dehydrogenase reductase Sdr
KM405_23245	COG0589	response to stress
KM405_23285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_23305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM405_23310	COG0827	DNA restriction-modification system
KM405_23315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM405_23320	COG3874	Sporulation protein YtfJ
KM405_23335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM405_23345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM405_23360	COG1104	cysteine desulfurase activity
KM405_23370	COG0583	DNA-binding transcription factor activity
KM405_23375	COG0697	spore germination
KM405_23385	COG1956	GAF domain-containing protein
KM405_23390	COG0626	cystathionine gamma-synthase activity
KM405_23420	COG1595	DNA-templated transcription, initiation
KM405_23430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM405_23435	COG0454	-acetyltransferase
KM405_23440	COG0517	IMP dehydrogenase activity
KM405_23445	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM405_23455	COG0745	RESPONSE REGULATOR receiver
KM405_23465	COG0666	response to abiotic stimulus
KM405_23500	COG1609	Transcriptional regulator
KM405_23505	COG4851	CamS sex pheromone cAM373 precursor
KM405_23510	COG3118	belongs to the thioredoxin family
KM405_23520	COG2309	aminopeptidase activity
KM405_23540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_23555	COG1674	ftsk spoiiie
KM405_23565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM405_23570	COG4848	Belongs to the UPF0354 family
KM405_23575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM405_23580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM405_23585	COG1363	Peptidase, m42
KM405_23595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_23610	COG0510	thiamine kinase activity
KM405_23615	COG1523	belongs to the glycosyl hydrolase 13 family
KM405_23630	COG1349	DNA-binding transcription factor activity
KM405_23635	COG1187	pseudouridine synthase activity
KM405_23640	COG2244	polysaccharide biosynthetic process
KM405_23645	COG2081	HI0933 family
KM405_23650	COG2814	Major facilitator Superfamily
KM405_23660	COG3832	glyoxalase III activity
KM405_23680	COG1329	Transcriptional regulator
KM405_23690	COG4975	Glucose uptake
KM405_23705	COG0314	molybdopterin synthase activity
KM405_23710	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM405_23715	COG0303	'Molybdopterin
KM405_23725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM405_23750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM405_23760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM405_23805	COG2814	Major facilitator Superfamily
KM405_23810	COG0475	glutathione-regulated potassium exporter activity
KM405_23815	COG0490	domain, Protein
KM405_23820	COG0582	viral genome integration into host DNA
KM405_23830	COG1136	(ABC) transporter
KM405_23850	COG1242	4 iron, 4 sulfur cluster binding
KM405_23855	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM405_23860	COG1131	(ABC) transporter
KM405_23870	COG1794	racemase activity, acting on amino acids and derivatives
KM405_23890	COG2267	carboxylic ester hydrolase activity
KM405_23895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM405_23900	COG0671	phosphoesterase, PA-phosphatase related
KM405_23905	COG0438	transferase activity, transferring glycosyl groups
KM405_23915	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM405_23965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM405_23970	COG5002	protein histidine kinase activity
KM405_23975	COG4191	Histidine kinase
KM405_23980	COG2267	carboxylic ester hydrolase activity
KM405_24000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM405_24005	COG1116	anion transmembrane transporter activity
KM405_24010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM405_24035	COG0494	nUDIX hydrolase
KM405_24065	COG0288	reversible hydration of carbon dioxide
KM405_24070	COG1271	oxidase subunit
KM405_24075	COG1294	oxidase, subunit
KM405_24095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_24120	COG1842	Phage shock protein A
KM405_24150	COG5002	protein histidine kinase activity
KM405_24155	COG0745	RESPONSE REGULATOR receiver
KM405_24185	COG1597	lipid kinase activity
KM405_24220	COG0586	Pfam SNARE associated Golgi protein
KM405_24230	COG0577	efflux transmembrane transporter activity
KM405_24235	COG1136	(ABC) transporter
KM405_24240	COG3708	Transcriptional regulator
KM405_24240	COG2207	Transcriptional regulator
KM405_24245	COG0745	RESPONSE REGULATOR receiver
KM405_24250	COG2205	protein histidine kinase activity
KM405_24255	COG0577	efflux transmembrane transporter activity
KM405_24265	COG0577	efflux transmembrane transporter activity
KM405_24270	COG1136	(ABC) transporter
KM405_24290	COG2188	Transcriptional regulator
KM405_24310	COG3964	amidohydrolase
KM405_24340	COG4948	Mandelate Racemase Muconate Lactonizing
KM405_24350	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM405_24355	COG0596	Alpha beta hydrolase
KM405_24360	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM405_24365	COG1169	isochorismate synthase
KM405_24370	COG1575	Belongs to the MenA family. Type 1 subfamily
KM405_24375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM405_24395	COG0058	SHG alpha-glucan phosphorylase activity
KM405_24400	COG0297	glycogen (starch) synthase activity
KM405_24405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM405_24525	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM405_24560	COG1285	pathogenesis
KM405_24565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM405_24575	COG0166	Belongs to the GPI family
KM405_24580	COG2155	Conserved Protein
KM405_24585	COG1098	S1 RNA binding domain
KM405_24590	COG0436	Aminotransferase
KM405_24595	COG1522	sequence-specific DNA binding
KM405_24600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM405_24605	COG2267	carboxylic ester hydrolase activity
KM405_24615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM405_24635	COG5018	Exonuclease
KM405_24640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM405_24660	COG2050	protein possibly involved in aromatic compounds catabolism
KM405_24670	COG1268	BioY protein
KM405_24680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM405_24685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM405_24700	COG3584	3D domain protein
KM405_24715	COG1252	NADH dehydrogenase
KM405_24730	COG3708	Transcriptional regulator
KM405_24745	COG1683	Conserved Protein
KM405_24765	COG0316	Belongs to the HesB IscA family
KM405_24780	COG1252	NADH dehydrogenase
KM405_24795	COG0390	transport system, permease component
KM405_24800	COG2824	Alkylphosphonate utilization operon protein PhnA
KM405_24840	COG4837	Protein of unknown function (DUF1462)
KM405_24845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM405_24855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM405_24860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM405_24870	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM405_24875	COG0647	UMP catabolic process
KM405_24885	COG2445	Protein of unknown function DUF86
KM405_24890	COG1494	fructose-1,6-bisphosphatase
KM405_24905	COG4470	Protein conserved in bacteria
KM405_24915	COG0789	Transcriptional regulator
KM405_24920	COG4377	Putative membrane peptidase family (DUF2324)
KM405_24945	COG0739	heme binding
KM405_24955	COG3377	Domain of unknown function (DUF1805)
KM405_24960	COG0737	Belongs to the 5'-nucleotidase family
KM405_24965	COG1695	Transcriptional regulator
KM405_24975	COG0719	Fe-S assembly protein
KM405_24980	COG0822	iron-sulfur transferase activity
KM405_24985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM405_24990	COG0719	Fe-S assembly protein
KM405_24995	COG0396	ATPase activity
KM405_25000	COG1464	Belongs to the NlpA lipoprotein family
KM405_25005	COG1464	Belongs to the NlpA lipoprotein family
KM405_25010	COG2011	ABC-type metal ion transport system permease component
KM405_25015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM405_25025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM405_25030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM405_25040	COG1393	Belongs to the ArsC family
KM405_25085	COG0039	L-malate dehydrogenase activity
KM405_25105	COG1309	transcriptional regulator
KM405_25110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM405_25115	COG1960	acyl-CoA dehydrogenase activity
KM405_25120	COG0183	Belongs to the thiolase family
KM405_25125	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM405_25125	COG1024	Enoyl-CoA hydratase
KM405_25135	COG1686	Belongs to the peptidase S11 family
KM405_25150	COG0011	TIGRFAM Protein of
KM405_25155	COG0840	transmembrane signaling receptor activity
KM405_25175	COG2814	Major facilitator Superfamily
KM405_25180	COG0531	amino acid
KM405_25190	COG0706	membrane insertase activity
KM405_25200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM405_25235	COG0586	Pfam SNARE associated Golgi protein
KM405_25245	COG1376	ErfK ybiS ycfS ynhG family protein
KM405_25250	COG0745	RESPONSE REGULATOR receiver
KM405_25255	COG5002	protein histidine kinase activity
KM405_25280	COG2151	metal-sulfur cluster biosynthetic enzyme
KM405_25285	COG3227	Zinc metalloprotease (Elastase)
KM405_25290	COG1741	Belongs to the pirin family
KM405_25305	COG0475	glutathione-regulated potassium exporter activity
KM405_25310	COG0490	domain, Protein
KM405_25315	COG1115	amino acid carrier protein
KM405_25320	COG0783	Belongs to the Dps family
KM405_25335	COG1611	Belongs to the LOG family
KM405_25355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_25360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_25365	COG1115	amino acid carrier protein
KM405_25370	COG1115	amino acid carrier protein
KM405_25375	COG2910	NAD(P)H-binding
KM405_25390	COG0656	L-ascorbic acid biosynthetic process
KM405_25395	COG2814	Major facilitator Superfamily
KM405_25400	COG1733	regulation of RNA biosynthetic process
KM405_25410	COG1252	NADH dehydrogenase
KM405_25415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM405_25420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM405_25430	COG3290	protein histidine kinase activity
KM405_25430	COG0840	transmembrane signaling receptor activity
KM405_25440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM405_25445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM405_25460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM405_25515	COG0557	exoribonuclease II activity
KM405_25520	COG1647	Serine aminopeptidase, S33
KM405_25525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM405_25530	COG1346	cytolysis
KM405_25625	COG4695	Portal protein
KM405_25650	COG4974	Belongs to the 'phage' integrase family
KM405_25660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM405_25665	COG0149	triose-phosphate isomerase activity
KM405_25675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM405_25690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM405_25715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM405_25730	COG2323	membrane
KM405_25735	COG0740	serine-type endopeptidase activity
KM405_25740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM405_25750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM405_25760	COG1051	belongs to the nudix hydrolase family
KM405_25770	COG0492	ferredoxin-NADP+ reductase activity
KM405_25775	COG0457	Tetratricopeptide repeat
KM405_25780	COG0110	maltose O-acetyltransferase activity
KM405_25800	COG1950	PFAM Membrane protein of
KM405_25810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM405_25815	COG0556	nucleotide-excision repair
KM405_25835	COG0789	Transcriptional regulator
KM405_25860	COG2855	membrane
KM405_25865	COG0583	DNA-binding transcription factor activity
KM405_25875	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM405_25880	COG0488	(ABC) transporter
KM405_25890	COG1132	(ABC) transporter
KM405_25895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM405_25900	COG3409	Peptidoglycan-binding domain 1 protein
KM405_25900	COG0793	Belongs to the peptidase S41A family
KM405_25905	COG2177	Part of the ABC transporter FtsEX involved in
KM405_25910	COG2884	Cell division ATP-binding protein ftsE
KM405_25925	COG0653	protein targeting
KM405_25930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM405_25935	COG1278	Cold shock
KM405_25940	COG1040	competence protein
KM405_25945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM405_25950	COG0791	NLP P60 protein
KM405_25950	COG1388	LysM domain
KM405_25955	COG1733	regulation of RNA biosynthetic process
KM405_25960	COG1307	EDD domain protein, DegV family
KM405_25965	COG1739	Uncharacterized protein family UPF0029
KM405_25970	COG1316	TRANSCRIPTIONal
KM405_25975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM405_25980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM405_25985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM405_25995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM405_25995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM405_26010	COG3394	polysaccharide catabolic process
KM405_26015	COG1486	melibiose metabolic process
KM405_26020	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM405_26025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM405_26035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM405_26040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM405_26045	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM405_26055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM405_26060	COG1301	dicarboxylic acid transport
KM405_26070	COG0346	lactoylglutathione lyase activity
KM405_26075	COG1511	domain protein
KM405_26080	COG0583	DNA-binding transcription factor activity
KM405_26085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM405_26100	COG1271	oxidase subunit
KM405_26105	COG1294	oxidase, subunit
KM405_26110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM405_26120	COG1620	l-lactate permease
KM405_26130	COG2389	metal-binding protein
KM405_26140	COG1368	sulfuric ester hydrolase activity
KM405_26155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM405_26165	COG1215	transferase activity, transferring glycosyl groups
KM405_26170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM405_26175	COG1388	LysM domain
KM405_26175	COG3584	3D domain protein
KM405_26200	COG4715	Zinc finger, swim domain protein
KM405_26205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM405_26245	COG0577	efflux transmembrane transporter activity
KM405_26250	COG1136	(ABC) transporter
KM405_26285	COG5002	protein histidine kinase activity
KM405_26290	COG0745	RESPONSE REGULATOR receiver
KM405_26295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM405_26310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM405_26315	COG1134	teichoic acid transport
KM405_26320	COG1682	transport, permease protein
KM405_26325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM405_26370	COG1609	Transcriptional regulator
KM405_26385	COG0739	heme binding
KM405_26405	COG2385	sporulation resulting in formation of a cellular spore
KM405_26420	COG4836	Membrane
KM405_26425	COG1007	ATP synthesis coupled electron transport
KM405_26430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM405_26435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM405_26445	COG0839	Belongs to the complex I subunit 6 family
KM405_26460	COG0649	NAD binding
KM405_26465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM405_26480	COG5001	Diguanylate cyclase
KM405_26480	COG3300	MHYT domain
KM405_26530	COG0356	it plays a direct role in the translocation of protons across the membrane
KM405_26565	COG0698	ribose 5-phosphate isomerase
KM405_26575	COG2190	(PTS) system
KM405_26580	COG2259	Doxx family
KM405_26585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM405_26600	COG0009	L-threonylcarbamoyladenylate synthase
KM405_26615	COG2890	protein-(glutamine-N5) methyltransferase activity
KM405_26635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM405_26640	COG1494	fructose-1,6-bisphosphatase
KM405_26660	COG4821	SIS domain
KM405_26670	COG3343	RNA polymerase activity
KM405_26680	COG1960	acyl-CoA dehydrogenase activity
KM405_26685	COG1960	acyl-CoA dehydrogenase activity
KM405_26690	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM405_26695	COG0183	Belongs to the thiolase family
KM405_26700	COG2181	nitrate reductase activity
KM405_26700	COG0247	lactate metabolic process
KM405_26705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM405_26715	COG5001	Diguanylate cyclase
KM405_26715	COG3300	MHYT domain
KM405_26735	COG2197	response regulator
KM405_26740	COG4585	Histidine kinase
KM405_26745	COG0842	Transport permease protein
KM405_26750	COG1131	(ABC) transporter
KM405_26755	COG0024	Methionine aminopeptidase
KM405_26765	COG2234	aminopeptidase activity
KM405_26785	COG1595	DNA-templated transcription, initiation
KM405_26790	COG0018	arginyl-trna synthetase
KM405_26795	COG4506	Protein conserved in bacteria
KM405_26800	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM405_26815	COG0010	Belongs to the arginase family
KM405_26825	COG2814	Major facilitator Superfamily
KM405_26830	COG0789	Transcriptional regulator
KM405_26835	COG0584	glycerophosphoryl diester phosphodiesterase
KM405_26840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM405_26850	COG1994	Peptidase M50
KM405_26860	COG1078	dGTPase activity
KM405_26865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM405_26870	COG1120	ATPase activity
KM405_26875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM405_26900	COG0095	Lipoate-protein ligase
KM405_26905	COG0280	phosphate acetyltransferase
KM405_26920	COG3773	Cell wall hydrolase
KM405_26930	COG2363	Small membrane protein
KM405_26940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM405_26945	COG2233	PERMEase
KM405_26950	COG0561	phosphatase activity
KM405_26955	COG2814	Major facilitator Superfamily
KM405_26965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM405_26970	COG1131	(ABC) transporter
KM405_26975	COG2755	lipolytic protein G-D-S-L family
KM405_26980	COG1609	Transcriptional regulator
KM405_26990	COG0460	homoserine dehydrogenase
KM405_27000	COG2873	o-acetylhomoserine
KM405_27010	COG1011	Hydrolase
KM405_27015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM405_27025	COG2197	response regulator
KM405_27035	COG0351	phosphomethylpyrimidine kinase
KM405_27040	COG3706	GGDEF domain
KM405_27045	COG2879	small protein
KM405_27050	COG1966	Carbon starvation protein
KM405_27055	COG3279	Response regulator of the LytR AlgR family
KM405_27060	COG0477	Major facilitator Superfamily
KM405_27085	COG0840	transmembrane signaling receptor activity
KM405_27095	COG1607	acyl-coa hydrolase
KM405_27110	COG0488	(ABC) transporter
KM405_27130	COG0463	Glycosyl transferase, family 2
KM405_27135	COG1309	transcriptional regulator
KM405_27140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM405_27145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM405_27145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM405_27150	COG0628	permease
KM405_27165	COG3279	Response regulator of the LytR AlgR family
KM405_27170	COG3275	phosphorelay sensor kinase activity
KM405_27175	COG2814	Major facilitator Superfamily
KM405_27180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM405_27185	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM405_27190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM405_27210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM405_27215	COG1272	protein, Hemolysin III
KM405_27235	COG0516	GMP reductase activity
KM405_27240	COG1164	Oligoendopeptidase f
KM405_27260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM405_27265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM405_27270	COG4853	Protein conserved in bacteria
KM405_27275	COG4863	YycH protein
KM405_27280	COG5002	protein histidine kinase activity
KM405_27285	COG0745	RESPONSE REGULATOR receiver
KM405_27315	COG0305	Participates in initiation and elongation during chromosome replication
KM405_27325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM405_27330	COG4241	membrane
KM405_27340	COG0629	single-stranded DNA binding
KM405_27350	COG0012	GTP binding
KM405_27355	COG4481	Protein conserved in bacteria
KM405_27360	COG0668	transmembrane transport
KM405_27370	COG1475	DNA binding
KM405_27375	COG1192	Involved in chromosome partitioning
KM405_27400	COG1847	R3H domain protein
KM405_27405	COG0706	membrane insertase activity
KM405_27415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM405_27465	COG3344	reverse transcriptase
KM405_27545	COG3344	reverse transcriptase
KM405_27740	COG4962	Type ii secretion system protein e
KM405_27875	COG2311	Membrane
KM405_27895	COG4196	transglutaminase domain protein
KM405_27900	COG0671	phosphoesterase, PA-phosphatase related
KM405_27915	COG1215	transferase activity, transferring glycosyl groups
KM405_27920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM405_27925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM405_28090	COG2002	toxin-antitoxin pair type II binding
KM405_28100	COG4974	Belongs to the 'phage' integrase family
KM405_28155	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM405_28165	COG4974	Belongs to the 'phage' integrase family
KM405_28190	COG0457	Tetratricopeptide repeat
KM405_28395	COG0791	NLP P60 protein
KM405_28395	COG0741	lytic transglycosylase activity
KM405_28460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM405_28520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM405_28530	COG4166	transmembrane transport
KM405_28570	COG1280	lysine exporter protein (LysE YggA)
KM405_28595	COG0681	Belongs to the peptidase S26 family
KM405_28670	COG1309	transcriptional regulator
KM405_28675	COG1683	Conserved Protein
KM405_28715	COG1192	Involved in chromosome partitioning