locus-tag	class	description
KM401_00010	COG0592	DNA-directed DNA polymerase activity
KM401_00015	COG2501	S4 domain
KM401_00025	COG0187	DNA topoisomerase II activity
KM401_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM401_00065	COG0516	GMP reductase activity
KM401_00065	COG0517	IMP dehydrogenase activity
KM401_00070	COG1686	Belongs to the peptidase S11 family
KM401_00100	COG1428	Deoxynucleoside kinase
KM401_00105	COG1428	Deoxynucleoside kinase
KM401_00110	COG1335	isochorismatase
KM401_00115	COG0590	tRNA wobble adenosine to inosine editing
KM401_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM401_00180	COG1982	Orn Lys Arg decarboxylase major
KM401_00190	COG0470	DNA polymerase III
KM401_00195	COG1774	PSP1 C-terminal conserved region
KM401_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM401_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM401_00220	COG2002	toxin-antitoxin pair type II binding
KM401_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_00230	COG0084	hydrolase, TatD family'
KM401_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM401_00250	COG4466	Protein conserved in bacteria
KM401_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM401_00270	COG0251	oxidation-reduction process
KM401_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM401_00305	COG2002	toxin-antitoxin pair type II binding
KM401_00310	COG2244	polysaccharide biosynthetic process
KM401_00315	COG3956	TIGRFAM MazG family protein
KM401_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM401_00340	COG1098	S1 RNA binding domain
KM401_00355	COG2208	phosphoserine phosphatase activity
KM401_00360	COG0037	tRNA processing
KM401_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM401_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM401_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM401_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM401_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM401_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM401_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM401_00420	COG1396	sequence-specific DNA binding
KM401_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM401_00455	COG3880	PFAM UvrB UvrC protein
KM401_00465	COG0542	response to heat
KM401_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM401_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM401_00500	COG1045	serine acetyltransferase
KM401_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM401_00520	COG3688	RNA-binding protein containing a PIN domain
KM401_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM401_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM401_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM401_00565	COG2813	Specifically methylates the guanine in position
KM401_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM401_00580	COG1358	cellular component organization or biogenesis
KM401_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM401_00710	COG0201	protein transport
KM401_00720	COG0024	Methionine aminopeptidase
KM401_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM401_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM401_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_00795	COG0489	protein tyrosine kinase activity
KM401_00805	COG2194	sulfuric ester hydrolase activity
KM401_00810	COG0726	polysaccharide deacetylase
KM401_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM401_00895	COG4856	YbbR-like protein
KM401_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM401_00915	COG0596	Alpha beta hydrolase
KM401_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM401_00940	COG4946	Tricorn protease homolog
KM401_00940	COG1506	peptidase
KM401_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM401_00975	COG2011	ABC-type metal ion transport system permease component
KM401_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_00985	COG1464	Belongs to the NlpA lipoprotein family
KM401_00990	COG0604	alcohol dehydrogenase
KM401_01000	COG0277	FAD linked oxidase domain protein
KM401_01005	COG2271	Major facilitator Superfamily
KM401_01015	COG2814	Major facilitator Superfamily
KM401_01030	COG0601	transmembrane transport
KM401_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_01040	COG0444	Belongs to the ABC transporter superfamily
KM401_01045	COG4608	Belongs to the ABC transporter superfamily
KM401_01050	COG4166	transmembrane transport
KM401_01060	COG2207	Transcriptional regulator
KM401_01075	COG4166	transmembrane transport
KM401_01080	COG4166	transmembrane transport
KM401_01085	COG0656	L-ascorbic acid biosynthetic process
KM401_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_01105	COG4149	molybdate abc transporter
KM401_01115	COG1910	domain protein
KM401_01125	COG0583	DNA-binding transcription factor activity
KM401_01130	COG0697	spore germination
KM401_01145	COG0204	Acyl-transferase
KM401_01155	COG1609	Transcriptional regulator
KM401_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_01175	COG0084	hydrolase, TatD family'
KM401_01180	COG5298	Protein conserved in bacteria
KM401_01205	COG0488	(ABC) transporter
KM401_01220	COG0747	negative chemotaxis
KM401_01225	COG0601	transmembrane transport
KM401_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_01235	COG0444	Belongs to the ABC transporter superfamily
KM401_01240	COG4608	Belongs to the ABC transporter superfamily
KM401_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM401_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM401_01290	COG2814	Major facilitator Superfamily
KM401_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM401_01310	COG4294	response to UV
KM401_01315	COG0457	Tetratricopeptide repeat
KM401_01315	COG0705	Rhomboid family
KM401_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM401_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM401_01335	COG0864	Transcriptional regulator
KM401_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM401_01345	COG2183	response to ionizing radiation
KM401_01440	COG0802	atpase or kinase
KM401_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM401_01450	COG0456	acetyltransferase
KM401_01460	COG0488	(ABC) transporter
KM401_01475	COG1266	CAAX protease self-immunity
KM401_01495	COG2252	PERMEase
KM401_01505	COG5002	protein histidine kinase activity
KM401_01535	COG2226	methyltransferase
KM401_01575	COG1968	undecaprenyl-diphosphatase activity
KM401_01590	COG2205	protein histidine kinase activity
KM401_01595	COG0745	RESPONSE REGULATOR receiver
KM401_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM401_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM401_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM401_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM401_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM401_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM401_01670	COG0151	Belongs to the GarS family
KM401_01695	COG0210	DNA helicase
KM401_01705	COG4851	CamS sex pheromone cAM373 precursor
KM401_01725	COG1335	isochorismatase
KM401_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_01735	COG2011	ABC-type metal ion transport system permease component
KM401_01740	COG1464	Belongs to the NlpA lipoprotein family
KM401_01760	COG1846	Transcriptional regulator
KM401_01785	COG1597	lipid kinase activity
KM401_01790	COG0546	phosphoglycolate phosphatase activity
KM401_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM401_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM401_01810	COG2076	Multidrug Resistance protein
KM401_01815	COG2309	aminopeptidase activity
KM401_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM401_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM401_01850	COG4807	Protein conserved in bacteria
KM401_01875	COG1757	Na H antiporter
KM401_01880	COG1473	amidohydrolase
KM401_01895	COG0450	alkyl hydroperoxide reductase
KM401_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_01940	COG0166	Belongs to the GPI family
KM401_01975	COG5002	protein histidine kinase activity
KM401_01995	COG3541	Predicted nucleotidyltransferase
KM401_02000	COG2814	Major facilitator Superfamily
KM401_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM401_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_02015	COG0765	amino acid transport
KM401_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_02030	COG0840	transmembrane signaling receptor activity
KM401_02035	COG0840	transmembrane signaling receptor activity
KM401_02040	COG0366	Alpha amylase catalytic
KM401_02045	COG1263	PTS System
KM401_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_02045	COG2190	(PTS) system
KM401_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM401_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_02100	COG1116	anion transmembrane transporter activity
KM401_02105	COG0488	(ABC) transporter
KM401_02150	COG2270	Major facilitator Superfamily
KM401_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_02180	COG2310	stress, protein
KM401_02185	COG2310	stress, protein
KM401_02190	COG2310	stress, protein
KM401_02195	COG0861	Integral membrane protein TerC family
KM401_02205	COG3853	Toxic anion resistance protein (TelA)
KM401_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM401_02230	COG1295	ribonuclease BN
KM401_02235	COG2217	Heavy metal translocating P-type atpase
KM401_02240	COG0697	spore germination
KM401_02260	COG0586	Pfam SNARE associated Golgi protein
KM401_02275	COG3871	stress protein (general stress protein 26)
KM401_02280	COG0387	Pfam Sodium calcium exchanger
KM401_02290	COG0535	radical SAM domain protein
KM401_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM401_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM401_02325	COG0582	viral genome integration into host DNA
KM401_02335	COG1396	sequence-specific DNA binding
KM401_02350	COG1396	sequence-specific DNA binding
KM401_02385	COG1484	DNA-dependent DNA replication
KM401_02615	COG0101	tRNA pseudouridine synthase activity
KM401_02625	COG3829	transcription factor binding
KM401_02635	COG0833	amino acid
KM401_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM401_02670	COG1263	PTS System
KM401_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_02690	COG0463	Glycosyl transferase, family 2
KM401_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM401_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM401_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM401_02745	COG1228	amidohydrolase
KM401_02750	COG1090	epimerase
KM401_02780	COG1988	membrane-bound metal-dependent
KM401_02785	COG1194	a g-specific adenine glycosylase
KM401_02810	COG1132	(ABC) transporter
KM401_02815	COG4129	membrane
KM401_02820	COG0070	glutamate synthase
KM401_02820	COG0067	glutamate synthase
KM401_02820	COG0069	glutamate synthase activity
KM401_02830	COG4555	ABC transporter
KM401_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM401_02855	COG0735	belongs to the Fur family
KM401_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM401_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM401_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM401_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM401_03005	COG2766	serine protein kinase
KM401_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM401_03040	COG2268	Band 7 protein
KM401_03050	COG3290	protein histidine kinase activity
KM401_03055	COG4565	transcriptional regulatory protein
KM401_03060	COG2851	Citrate transporter
KM401_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM401_03085	COG3842	ATPase activity
KM401_03090	COG1175	transmembrane transport
KM401_03095	COG0395	ABC-type sugar transport system, permease component
KM401_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM401_03110	COG0745	RESPONSE REGULATOR receiver
KM401_03115	COG5002	protein histidine kinase activity
KM401_03125	COG4990	cell redox homeostasis
KM401_03135	COG3290	protein histidine kinase activity
KM401_03140	COG4565	transcriptional regulatory protein
KM401_03145	COG3493	citrate carrier protein
KM401_03150	COG0281	malic enzyme
KM401_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_03175	COG5002	protein histidine kinase activity
KM401_03180	COG0745	RESPONSE REGULATOR receiver
KM401_03185	COG0456	acetyltransferase
KM401_03185	COG0454	-acetyltransferase
KM401_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM401_03195	COG3383	formate dehydrogenase (NAD+) activity
KM401_03200	COG2427	Protein of unknown function (DUF1641)
KM401_03215	COG0531	amino acid
KM401_03220	COG0640	Transcriptional regulator
KM401_03225	COG2217	Heavy metal translocating P-type atpase
KM401_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM401_03245	COG3227	Zinc metalloprotease (Elastase)
KM401_03265	COG2720	vancomycin resistance protein
KM401_03270	COG1316	TRANSCRIPTIONal
KM401_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_03280	COG0346	lactoylglutathione lyase activity
KM401_03285	COG1253	flavin adenine dinucleotide binding
KM401_03290	COG1027	Aspartate ammonia-lyase
KM401_03295	COG1620	l-lactate permease
KM401_03310	COG3104	oligopeptide transport
KM401_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_03335	COG2226	methyltransferase
KM401_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM401_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM401_03360	COG0714	Associated with various cellular activities
KM401_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_03385	COG0531	amino acid
KM401_03390	COG2188	Transcriptional regulator
KM401_03395	COG1263	PTS System
KM401_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_03400	COG0366	Alpha amylase catalytic
KM401_03415	COG0697	spore germination
KM401_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_03430	COG1115	amino acid carrier protein
KM401_03435	COG1126	abc transporter atp-binding protein
KM401_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_03445	COG0765	amino acid transport
KM401_03450	COG0765	amino acid transport
KM401_03455	COG0833	amino acid
KM401_03480	COG2378	regulation of single-species biofilm formation
KM401_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM401_03490	COG5002	protein histidine kinase activity
KM401_03505	COG0659	secondary active sulfate transmembrane transporter activity
KM401_03520	COG0747	negative chemotaxis
KM401_03530	COG0601	transmembrane transport
KM401_03535	COG4608	Belongs to the ABC transporter superfamily
KM401_03545	COG2271	Major facilitator Superfamily
KM401_03550	COG1846	Transcriptional regulator
KM401_03560	COG1609	Transcriptional regulator
KM401_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM401_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM401_03585	COG1879	ABC-type sugar transport system periplasmic component
KM401_03610	COG1063	alcohol dehydrogenase
KM401_03625	COG3568	Endonuclease Exonuclease Phosphatase
KM401_03650	COG1968	undecaprenyl-diphosphatase activity
KM401_03655	COG0840	transmembrane signaling receptor activity
KM401_03660	COG3584	3D domain protein
KM401_03660	COG1388	LysM domain
KM401_03665	COG1476	TRANSCRIPTIONal
KM401_03680	COG3104	oligopeptide transport
KM401_03685	COG1114	Component of the transport system for branched-chain amino acids
KM401_03700	COG1113	amino acid transport
KM401_03705	COG2252	PERMEase
KM401_03730	COG0475	glutathione-regulated potassium exporter activity
KM401_03730	COG0569	domain protein
KM401_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM401_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM401_03755	COG0833	amino acid
KM401_03760	COG4990	cell redox homeostasis
KM401_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_03780	COG0697	spore germination
KM401_03785	COG0531	amino acid
KM401_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_03805	COG1918	ferrous iron import across plasma membrane
KM401_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM401_03815	COG0573	inorganic phosphate transmembrane transporter activity
KM401_03820	COG0581	inorganic phosphate transmembrane transporter activity
KM401_03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM401_03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM401_03975	COG1116	anion transmembrane transporter activity
KM401_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_03990	COG0352	thiamine-phosphate diphosphorylase activity
KM401_03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_04000	COG2104	thiamine diphosphate biosynthetic process
KM401_04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_04015	COG0351	phosphomethylpyrimidine kinase
KM401_04055	COG2205	protein histidine kinase activity
KM401_04060	COG2814	Major facilitator Superfamily
KM401_04065	COG1846	Transcriptional regulator
KM401_04080	COG2252	PERMEase
KM401_04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM401_04105	COG1621	beta-fructofuranosidase activity
KM401_04110	COG1263	PTS System
KM401_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_04115	COG1609	Transcriptional regulator
KM401_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM401_04165	COG0778	Nitroreductase
KM401_04170	COG2719	SpoVR family
KM401_04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM401_04200	COG1937	Protein conserved in bacteria
KM401_04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM401_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM401_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM401_04235	COG0730	response to heat
KM401_04245	COG1316	TRANSCRIPTIONal
KM401_04250	COG0604	alcohol dehydrogenase
KM401_04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM401_04270	COG3711	transcriptional antiterminator
KM401_04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_04300	COG3584	3D domain protein
KM401_04300	COG1388	LysM domain
KM401_04305	COG0577	efflux transmembrane transporter activity
KM401_04310	COG1136	(ABC) transporter
KM401_04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM401_04335	COG1114	Component of the transport system for branched-chain amino acids
KM401_04340	COG3546	catalase activity
KM401_04375	COG0586	Pfam SNARE associated Golgi protein
KM401_04410	COG0531	amino acid
KM401_04415	COG0475	glutathione-regulated potassium exporter activity
KM401_04425	COG1737	Transcriptional regulator
KM401_04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_04435	COG1263	PTS System
KM401_04445	COG2259	Doxx family
KM401_04460	COG0697	spore germination
KM401_04465	COG1522	sequence-specific DNA binding
KM401_04480	COG2076	Multidrug Resistance protein
KM401_04485	COG1309	transcriptional regulator
KM401_04490	COG2814	Major facilitator Superfamily
KM401_04495	COG1733	regulation of RNA biosynthetic process
KM401_04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_04510	COG4533	DNA binding
KM401_04515	COG2211	Major facilitator Superfamily
KM401_04525	COG0693	protein deglycase activity
KM401_04530	COG0753	catalase activity
KM401_04530	COG0693	protein deglycase activity
KM401_04540	COG0531	amino acid
KM401_04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM401_04555	COG1012	belongs to the aldehyde dehydrogenase family
KM401_04560	COG1132	(ABC) transporter
KM401_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_04575	COG0765	amino acid transport
KM401_04580	COG1126	abc transporter atp-binding protein
KM401_04595	COG0189	ligase activity
KM401_04625	COG0028	Belongs to the TPP enzyme family
KM401_04630	COG3527	Alpha-acetolactate decarboxylase
KM401_04645	COG0561	phosphatase activity
KM401_04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM401_04675	COG0659	secondary active sulfate transmembrane transporter activity
KM401_04695	COG0653	protein targeting
KM401_04700	COG2244	polysaccharide biosynthetic process
KM401_04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_04715	COG4196	transglutaminase domain protein
KM401_04730	COG1696	Membrane protein involved in D-alanine export
KM401_04745	COG1024	Enoyl-CoA hydratase
KM401_04765	COG1363	Peptidase, m42
KM401_04785	COG3938	Belongs to the proline racemase family
KM401_04825	COG0601	transmembrane transport
KM401_04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_04840	COG4608	Belongs to the ABC transporter superfamily
KM401_04845	COG0322	excinuclease ABC activity
KM401_04875	COG0477	Major facilitator Superfamily
KM401_04880	COG3290	protein histidine kinase activity
KM401_04885	COG4565	transcriptional regulatory protein
KM401_04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM401_04920	COG4978	Transcriptional regulator
KM401_04920	COG0789	Transcriptional regulator
KM401_04935	COG0305	Participates in initiation and elongation during chromosome replication
KM401_04975	COG0477	Major facilitator Superfamily
KM401_05020	COG3320	Male sterility
KM401_05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_05025	COG1309	transcriptional regulator
KM401_05045	COG1183	phosphatidylcholine synthase activity
KM401_05065	COG2376	Dihydroxyacetone kinase
KM401_05075	COG2376	Dihydroxyacetone kinase
KM401_05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_05085	COG1959	2 iron, 2 sulfur cluster binding
KM401_05115	COG2770	Histidine kinase
KM401_05115	COG3437	response regulator, receiver
KM401_05165	COG3237	CsbD-like
KM401_05190	COG1191	sigma factor activity
KM401_05200	COG2208	phosphoserine phosphatase activity
KM401_05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM401_05210	COG0784	Response regulator, receiver
KM401_05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_05210	COG2198	Histidine kinase
KM401_05210	COG2205	protein histidine kinase activity
KM401_05265	COG0420	3'-5' exonuclease activity
KM401_05270	COG4717	serine-type aminopeptidase activity
KM401_05290	COG1309	transcriptional regulator
KM401_05295	COG2814	Major facilitator Superfamily
KM401_05300	COG0346	lactoylglutathione lyase activity
KM401_05310	COG0346	lactoylglutathione lyase activity
KM401_05315	COG0457	Tetratricopeptide repeat
KM401_05320	COG2267	carboxylic ester hydrolase activity
KM401_05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM401_05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM401_05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM401_05395	COG0477	Major facilitator Superfamily
KM401_05400	COG0477	Major facilitator Superfamily
KM401_05410	COG3973	AAA domain
KM401_05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_05435	COG4980	gas vesicle protein
KM401_05440	COG0537	adenosine 5'-monophosphoramidase activity
KM401_05445	COG1131	(ABC) transporter
KM401_05450	COG4473	ABC transporter
KM401_05465	COG1309	transcriptional regulator
KM401_05475	COG3402	PFAM membrane-flanked domain
KM401_05525	COG3402	PFAM membrane-flanked domain
KM401_05530	COG3428	Bacterial PH domain
KM401_05535	COG2329	Antibiotic biosynthesis monooxygenase
KM401_05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM401_05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM401_05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM401_05590	COG1309	transcriptional regulator
KM401_05595	COG1511	domain protein
KM401_05620	COG1609	Transcriptional regulator
KM401_05630	COG1234	tRNA 3'-trailer cleavage
KM401_05635	COG0095	Lipoate-protein ligase
KM401_05645	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_05675	COG3209	COG3209 Rhs family protein
KM401_05715	COG1078	dGTPase activity
KM401_05725	COG1595	DNA-templated transcription, initiation
KM401_05730	COG2207	Transcriptional regulator
KM401_05730	COG3708	Transcriptional regulator
KM401_05745	COG2205	protein histidine kinase activity
KM401_05750	COG0745	RESPONSE REGULATOR receiver
KM401_05775	COG0501	Belongs to the peptidase M48B family
KM401_05780	COG0840	transmembrane signaling receptor activity
KM401_05785	COG0697	spore germination
KM401_05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM401_05810	COG2224	Isocitrate lyase
KM401_05835	COG4903	ComK protein
KM401_05840	COG0398	Pfam SNARE associated Golgi protein
KM401_05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM401_05855	COG1074	ATP-dependent DNA helicase activity
KM401_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM401_05925	COG0367	asparagine synthase
KM401_05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM401_05935	COG0753	catalase activity
KM401_05940	COG0004	ammonium transporteR
KM401_05960	COG2996	Protein conserved in bacteria
KM401_05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_05995	COG0561	phosphatase activity
KM401_06005	COG0542	response to heat
KM401_06015	COG2267	carboxylic ester hydrolase activity
KM401_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM401_06040	COG5504	Zn-dependent protease
KM401_06050	COG0180	Tryptophanyl-tRNA synthetase
KM401_06060	COG4166	transmembrane transport
KM401_06065	COG0601	transmembrane transport
KM401_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_06075	COG0444	Belongs to the ABC transporter superfamily
KM401_06080	COG4608	Belongs to the ABC transporter superfamily
KM401_06085	COG0534	Mate efflux family protein
KM401_06090	COG4166	transmembrane transport
KM401_06105	COG0861	Integral membrane protein TerC family
KM401_06110	COG4862	establishment of competence for transformation
KM401_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_06125	COG1164	Oligoendopeptidase f
KM401_06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM401_06140	COG2346	COG2346, Truncated hemoglobins
KM401_06145	COG4116	CYTH
KM401_06155	COG2357	RelA SpoT domain protein
KM401_06165	COG0564	pseudouridine synthase activity
KM401_06185	COG0463	Glycosyl transferase, family 2
KM401_06185	COG1216	Glycosyl transferase, family 2
KM401_06205	COG0457	Tetratricopeptide repeat
KM401_06205	COG0463	Glycosyl transferase, family 2
KM401_06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM401_06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM401_06285	COG2153	protein acetylation
KM401_06295	COG2382	esterase
KM401_06310	COG5492	domain, Protein
KM401_06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
KM401_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM401_06360	COG1620	l-lactate permease
KM401_06365	COG5634	Uncharacterized conserved protein (DUF2278)
KM401_06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_06430	COG1476	TRANSCRIPTIONal
KM401_06490	COG2226	methyltransferase
KM401_06500	COG1686	Belongs to the peptidase S11 family
KM401_06505	COG0681	Belongs to the peptidase S26 family
KM401_06540	COG1012	belongs to the aldehyde dehydrogenase family
KM401_06545	COG3842	ATPase activity
KM401_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM401_06555	COG1177	transmembrane transport
KM401_06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM401_06570	COG2409	Drug exporters of the RND superfamily
KM401_06580	COG0564	pseudouridine synthase activity
KM401_06590	COG2340	Cysteine-rich secretory protein family
KM401_06595	COG0247	lactate metabolic process
KM401_06600	COG0277	FAD linked oxidase domain protein
KM401_06605	COG3835	regulator
KM401_06615	COG0745	RESPONSE REGULATOR receiver
KM401_06620	COG5002	protein histidine kinase activity
KM401_06625	COG2186	Transcriptional regulator
KM401_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM401_06660	COG2116	formate transmembrane transporter activity
KM401_06665	COG0861	Integral membrane protein TerC family
KM401_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_06680	COG2030	dehydratase
KM401_06700	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM401_06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_06730	COG1840	ABC-type Fe3 transport system, periplasmic component
KM401_06760	COG1349	DNA-binding transcription factor activity
KM401_06780	COG2861	carbohydrate metabolic process
KM401_06790	COG3852	Histidine kinase
KM401_06795	COG1846	Transcriptional regulator
KM401_06805	COG2318	DinB family
KM401_06810	COG5002	protein histidine kinase activity
KM401_06820	COG0720	synthase
KM401_06835	COG4873	Protein conserved in bacteria
KM401_06865	COG1780	Probably involved in ribonucleotide reductase function
KM401_06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM401_06890	COG1725	Transcriptional regulator
KM401_06895	COG1131	(ABC) transporter
KM401_06905	COG1131	(ABC) transporter
KM401_06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_06925	COG1522	sequence-specific DNA binding
KM401_06935	COG1335	isochorismatase
KM401_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_06950	COG2070	2-Nitropropane dioxygenase
KM401_06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM401_06965	COG1696	Membrane protein involved in D-alanine export
KM401_06985	COG0716	FMN binding
KM401_07000	COG3173	Aminoglycoside phosphotransferase
KM401_07020	COG0534	Mate efflux family protein
KM401_07025	COG1968	undecaprenyl-diphosphatase activity
KM401_07040	COG1846	Transcriptional regulator
KM401_07050	COG1301	dicarboxylic acid transport
KM401_07055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_07060	COG4709	membrane
KM401_07065	COG3874	Sporulation protein YtfJ
KM401_07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_07095	COG0028	Belongs to the TPP enzyme family
KM401_07100	COG0440	acetolactate synthase activity
KM401_07105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM401_07115	COG0473	3-isopropylmalate dehydrogenase activity
KM401_07140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM401_07175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM401_07190	COG1183	phosphatidylcholine synthase activity
KM401_07195	COG1368	sulfuric ester hydrolase activity
KM401_07205	COG0019	diaminopimelate decarboxylase activity
KM401_07225	COG0529	Catalyzes the synthesis of activated sulfate
KM401_07230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM401_07250	COG1648	precorrin-2 dehydrogenase activity
KM401_07255	COG0733	neurotransmitter:sodium symporter activity
KM401_07275	COG1757	Na H antiporter
KM401_07290	COG4758	membrane
KM401_07295	COG4585	Histidine kinase
KM401_07300	COG2197	response regulator
KM401_07310	COG1114	Component of the transport system for branched-chain amino acids
KM401_07320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM401_07345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM401_07345	COG1017	nitric oxide dioxygenase activity
KM401_07360	COG0730	response to heat
KM401_07365	COG0306	phosphate transporter
KM401_07370	COG1392	Phosphate transport regulator
KM401_07375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_07390	COG3852	Histidine kinase
KM401_07395	COG1801	Protein of unknown function DUF72
KM401_07405	COG0582	viral genome integration into host DNA
KM401_07430	COG0392	lysyltransferase activity
KM401_07430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM401_07445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_07450	COG1686	Belongs to the peptidase S11 family
KM401_07455	COG2715	membrane protein required for spore maturation
KM401_07460	COG0700	Nucleoside recognition
KM401_07465	COG1187	pseudouridine synthase activity
KM401_07475	COG1333	cytochrome c biogenesis protein
KM401_07480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM401_07485	COG0745	RESPONSE REGULATOR receiver
KM401_07490	COG5002	protein histidine kinase activity
KM401_07495	COG2096	Adenosyltransferase
KM401_07510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM401_07515	COG1141	Ferredoxin
KM401_07520	COG4955	Helix-turn-helix domain
KM401_07525	COG0514	ATP-dependent DNA helicase (RecQ)
KM401_07530	COG1266	CAAX protease self-immunity
KM401_07550	COG4862	establishment of competence for transformation
KM401_07555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM401_07575	COG0492	ferredoxin-NADP+ reductase activity
KM401_07650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_07665	COG0142	geranyltranstransferase activity
KM401_07675	COG0142	geranyltranstransferase activity
KM401_07695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM401_07700	COG0457	Tetratricopeptide repeat
KM401_07720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM401_07730	COG4347	Protein of unknown function (DUF1405)
KM401_07745	COG2738	Putative neutral zinc metallopeptidase
KM401_07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_07760	COG1694	Mazg nucleotide pyrophosphohydrolase
KM401_07775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_07780	COG0438	transferase activity, transferring glycosyl groups
KM401_07815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM401_07815	COG1199	ATP-dependent helicase activity
KM401_07835	COG3935	DnaD domain protein
KM401_07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM401_07910	COG0116	Belongs to the methyltransferase superfamily
KM401_07920	COG1199	ATP-dependent helicase activity
KM401_07925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM401_07935	COG3173	Aminoglycoside phosphotransferase
KM401_07940	COG0024	Methionine aminopeptidase
KM401_07950	COG2233	PERMEase
KM401_07955	COG2311	Membrane
KM401_07960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_07970	COG0456	acetyltransferase
KM401_08020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_08045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM401_08060	COG1215	transferase activity, transferring glycosyl groups
KM401_08065	COG0438	transferase activity, transferring glycosyl groups
KM401_08080	COG0454	-acetyltransferase
KM401_08100	COG0328	RNA-DNA hybrid ribonuclease activity
KM401_08140	COG1280	lysine exporter protein (LysE YggA)
KM401_08155	COG3162	membrane
KM401_08160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_08165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_08175	COG0475	glutathione-regulated potassium exporter activity
KM401_08180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_08185	COG0789	Transcriptional regulator
KM401_08185	COG4978	Transcriptional regulator
KM401_08195	COG2323	membrane
KM401_08200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM401_08255	COG1923	regulation of RNA biosynthetic process
KM401_08265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM401_08270	COG1360	Flagellar Motor Protein
KM401_08275	COG2201	protein-glutamate methylesterase activity
KM401_08280	COG0643	Histidine kinase
KM401_08280	COG2198	Histidine kinase
KM401_08285	COG2198	Histidine kinase
KM401_08285	COG0643	Histidine kinase
KM401_08290	COG1776	CheC inhibitor of MCP methylation
KM401_08290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_08305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM401_08325	COG1256	bacterial-type flagellum assembly
KM401_08350	COG1815	bacterial-type flagellum-dependent cell motility
KM401_08355	COG1558	bacterial-type flagellum-dependent cell motility
KM401_08370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_08380	COG1157	protein secretion by the type III secretion system
KM401_08420	COG0835	chemotaxis
KM401_08420	COG0784	Response regulator, receiver
KM401_08430	COG0463	Glycosyl transferase, family 2
KM401_08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM401_08470	COG0741	lytic transglycosylase activity
KM401_08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_08485	COG1776	CheC inhibitor of MCP methylation
KM401_08495	COG1338	Plays a role in the flagellum-specific transport system
KM401_08500	COG1987	bacterial-type flagellum assembly
KM401_08510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM401_08515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM401_08520	COG1419	protein localization to endoplasmic reticulum
KM401_08525	COG4786	Flagellar basal body rod
KM401_08530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_08555	COG1309	transcriptional regulator
KM401_08575	COG2329	Antibiotic biosynthesis monooxygenase
KM401_08600	COG0583	DNA-binding transcription factor activity
KM401_08605	COG3842	ATPase activity
KM401_08610	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM401_08620	COG1234	tRNA 3'-trailer cleavage
KM401_08645	COG1686	Belongs to the peptidase S11 family
KM401_08655	COG0406	alpha-ribazole phosphatase activity
KM401_08685	COG0367	asparagine synthase
KM401_08715	COG1802	Transcriptional regulator
KM401_08720	COG0697	spore germination
KM401_08725	COG0523	cobalamin synthesis protein
KM401_08730	COG0701	Predicted permease
KM401_08740	COG0438	transferase activity, transferring glycosyl groups
KM401_08740	COG1216	Glycosyl transferase, family 2
KM401_08745	COG1757	Na H antiporter
KM401_08750	COG0114	fumarate hydratase activity
KM401_08775	COG3340	Belongs to the peptidase S51 family
KM401_08795	COG0785	Cytochrome C biogenesis protein
KM401_08825	COG2733	membrane
KM401_08860	COG1131	(ABC) transporter
KM401_08875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_08880	COG0528	UMP kinase activity
KM401_08890	COG1027	Aspartate ammonia-lyase
KM401_08895	COG0281	malic enzyme
KM401_08900	COG4191	Histidine kinase
KM401_08905	COG0784	Response regulator, receiver
KM401_08910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_08965	COG1051	belongs to the nudix hydrolase family
KM401_08970	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_08980	COG2814	Major facilitator Superfamily
KM401_08995	COG1966	Carbon starvation protein
KM401_09010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_09020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM401_09030	COG2223	nitrite transmembrane transporter activity
KM401_09035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_09050	COG2244	polysaccharide biosynthetic process
KM401_09055	COG0733	neurotransmitter:sodium symporter activity
KM401_09065	COG5566	PFAM Mor transcription activator
KM401_09070	COG2323	membrane
KM401_09085	COG2084	Dehydrogenase
KM401_09100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_09110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_09115	COG0028	Belongs to the TPP enzyme family
KM401_09120	COG0440	acetolactate synthase activity
KM401_09125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM401_09135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM401_09160	COG2814	Major facilitator Superfamily
KM401_09165	COG3384	dioxygenase
KM401_09175	COG3279	Response regulator of the LytR AlgR family
KM401_09180	COG0427	acetyl-CoA hydrolase
KM401_09200	COG1073	alpha beta
KM401_09230	COG0535	radical SAM domain protein
KM401_09235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_09255	COG1914	H( )-stimulated, divalent metal cation uptake system
KM401_09270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM401_09300	COG2390	Transcriptional regulator
KM401_09310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_09315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM401_09330	COG4224	UPF0291 protein
KM401_09350	COG0006	proline dipeptidase activity
KM401_09355	COG2132	Multicopper oxidase
KM401_09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM401_09385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_09400	COG1276	copper resistance
KM401_09400	COG2372	response to copper ion
KM401_09405	COG4549	nuclear export factor GLE1
KM401_09415	COG0697	spore germination
KM401_09420	COG0583	DNA-binding transcription factor activity
KM401_09425	COG1959	2 iron, 2 sulfur cluster binding
KM401_09430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM401_09435	COG0778	Nitroreductase
KM401_09445	COG0628	permease
KM401_09455	COG1231	oxidoreductase activity
KM401_09460	COG0523	cobalamin synthesis protein
KM401_09475	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_09480	COG2030	dehydratase
KM401_09485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_09495	COG0411	ABC transporter
KM401_09515	COG0583	DNA-binding transcription factor activity
KM401_09525	COG1942	4-Oxalocrotonate Tautomerase
KM401_09545	COG1271	oxidase subunit
KM401_09550	COG1294	oxidase, subunit
KM401_09555	COG4988	ABC transporter
KM401_09560	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM401_09580	COG1686	Belongs to the peptidase S11 family
KM401_09595	COG1388	LysM domain
KM401_09595	COG0791	NLP P60 protein
KM401_09610	COG0745	RESPONSE REGULATOR receiver
KM401_09615	COG5002	protein histidine kinase activity
KM401_09625	COG0300	oxidoreductase activity
KM401_09660	COG0460	homoserine dehydrogenase
KM401_09685	COG1316	TRANSCRIPTIONal
KM401_09695	COG0745	RESPONSE REGULATOR receiver
KM401_09700	COG5002	protein histidine kinase activity
KM401_09715	COG1285	pathogenesis
KM401_09720	COG1247	-acetyltransferase
KM401_09740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_09750	COG1082	Xylose isomerase domain protein TIM barrel
KM401_09765	COG1279	arginine transmembrane transporter activity
KM401_09775	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM401_09815	COG2002	toxin-antitoxin pair type II binding
KM401_09820	COG1404	Belongs to the peptidase S8 family
KM401_09825	COG0640	Transcriptional regulator
KM401_09830	COG0667	Aldo Keto reductase
KM401_09835	COG2814	Major facilitator Superfamily
KM401_09860	COG0840	transmembrane signaling receptor activity
KM401_09875	COG3949	Membrane
KM401_09880	COG0783	Belongs to the Dps family
KM401_09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_09905	COG1231	oxidoreductase activity
KM401_09915	COG4989	oxidoreductase activity
KM401_09920	COG0523	cobalamin synthesis protein
KM401_09925	COG0456	acetyltransferase
KM401_09980	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM401_09980	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM401_09990	COG0702	epimerase
KM401_10000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM401_10010	COG4166	transmembrane transport
KM401_10025	COG0406	alpha-ribazole phosphatase activity
KM401_10035	COG5337	Spore coat protein CotH
KM401_10040	COG1051	belongs to the nudix hydrolase family
KM401_10045	COG0586	Pfam SNARE associated Golgi protein
KM401_10050	COG2244	polysaccharide biosynthetic process
KM401_10060	COG0701	Predicted permease
KM401_10065	COG3689	TIGRFAM TIGR03943 family protein
KM401_10070	COG1607	acyl-coa hydrolase
KM401_10080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_10095	COG0702	epimerase
KM401_10100	COG2839	Protein conserved in bacteria
KM401_10105	COG1253	flavin adenine dinucleotide binding
KM401_10120	COG1114	Component of the transport system for branched-chain amino acids
KM401_10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_10145	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_10155	COG1876	peptidase activity
KM401_10165	COG0154	amidase activity
KM401_10170	COG2211	Major facilitator Superfamily
KM401_10190	COG0561	phosphatase activity
KM401_10200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM401_10205	COG4106	trans-aconitate 2-methyltransferase activity
KM401_10220	COG1819	glycosyl
KM401_10225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_10255	COG0456	acetyltransferase
KM401_10305	COG3874	Sporulation protein YtfJ
KM401_10330	COG2226	methyltransferase
KM401_10355	COG0346	lactoylglutathione lyase activity
KM401_10365	COG0604	alcohol dehydrogenase
KM401_10370	COG1595	DNA-templated transcription, initiation
KM401_10395	COG0386	Belongs to the glutathione peroxidase family
KM401_10400	COG1305	Transglutaminase-like
KM401_10405	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM401_10410	COG0714	Associated with various cellular activities
KM401_10425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM401_10430	COG1140	nitrate reductase beta subunit
KM401_10435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM401_10440	COG2181	nitrate reductase activity
KM401_10460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM401_10465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM401_10470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_10475	COG0303	'Molybdopterin
KM401_10480	COG0314	molybdopterin synthase activity
KM401_10490	COG2223	nitrite transmembrane transporter activity
KM401_10505	COG1648	precorrin-2 dehydrogenase activity
KM401_10515	COG1587	Uroporphyrinogen-III synthase
KM401_10515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM401_10520	COG2146	nitrite reductase [NAD(P)H] activity
KM401_10525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM401_10530	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM401_10565	COG2359	stage V sporulation protein S
KM401_10580	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM401_10595	COG1418	mRNA catabolic process
KM401_10600	COG0488	(ABC) transporter
KM401_10615	COG0629	single-stranded DNA binding
KM401_10630	COG1413	lyase activity
KM401_10645	COG2136	Putative SAM-dependent methyltransferase
KM401_10645	COG2521	methyltransferase
KM401_10650	COG0018	arginyl-trna synthetase
KM401_10675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM401_10695	COG0017	Asparaginyl-tRNA synthetase
KM401_10715	COG1674	ftsk spoiiie
KM401_10785	COG1929	Belongs to the glycerate kinase type-1 family
KM401_10790	COG0471	metal ion transport
KM401_10795	COG0745	RESPONSE REGULATOR receiver
KM401_10800	COG3850	Histidine kinase
KM401_10800	COG5002	protein histidine kinase activity
KM401_10815	COG0733	neurotransmitter:sodium symporter activity
KM401_10840	COG2610	gluconate transmembrane transporter activity
KM401_10845	COG1454	alcohol dehydrogenase
KM401_10850	COG1794	racemase activity, acting on amino acids and derivatives
KM401_10860	COG0456	acetyltransferase
KM401_10875	COG1131	(ABC) transporter
KM401_10890	COG0546	phosphoglycolate phosphatase activity
KM401_10910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_10925	COG0768	penicillin binding
KM401_10930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_10935	COG0204	Acyl-transferase
KM401_10940	COG1272	protein, Hemolysin III
KM401_10950	COG0805	protein transport
KM401_10960	COG1307	EDD domain protein, DegV family
KM401_10965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM401_10970	COG1999	signal sequence binding
KM401_10975	COG0071	Belongs to the small heat shock protein (HSP20) family
KM401_10980	COG0367	asparagine synthase
KM401_10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_11025	COG1051	belongs to the nudix hydrolase family
KM401_11035	COG0668	transmembrane transport
KM401_11040	COG2203	Gaf domain
KM401_11040	COG4585	Histidine kinase
KM401_11045	COG2197	response regulator
KM401_11055	COG1064	alcohol dehydrogenase
KM401_11080	COG1070	Carbohydrate kinase
KM401_11085	COG1070	Carbohydrate kinase
KM401_11115	COG0517	IMP dehydrogenase activity
KM401_11115	COG1125	glycine betaine transport
KM401_11120	COG1174	glycine betaine transport
KM401_11155	COG1253	flavin adenine dinucleotide binding
KM401_11160	COG1012	belongs to the aldehyde dehydrogenase family
KM401_11165	COG5506	Protein of unknown function (DUF1694)
KM401_11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_11185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM401_11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM401_11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM401_11200	COG0456	acetyltransferase
KM401_11205	COG3829	transcription factor binding
KM401_11210	COG1509	lysine 2,3-aminomutase activity
KM401_11250	COG4326	sporulation control protein
KM401_11255	COG0671	phosphoesterase, PA-phosphatase related
KM401_11260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM401_11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_11295	COG1715	Restriction endonuclease
KM401_11295	COG1787	Restriction endonuclease
KM401_11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM401_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_11430	COG2814	Major facilitator Superfamily
KM401_11435	COG4841	protein insertion into membrane
KM401_11440	COG0372	Belongs to the citrate synthase family
KM401_11445	COG2079	MmgE PrpD family protein
KM401_11450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM401_11455	COG1960	acyl-CoA dehydrogenase activity
KM401_11460	COG2084	Dehydrogenase
KM401_11470	COG1280	lysine exporter protein (LysE YggA)
KM401_11475	COG1024	Enoyl-CoA hydratase
KM401_11490	COG0420	3'-5' exonuclease activity
KM401_11495	COG0419	ATPase involved in DNA repair
KM401_11520	COG2223	nitrite transmembrane transporter activity
KM401_11525	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_11530	COG1169	isochorismate synthase
KM401_11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM401_11540	COG3433	isochorismatase activity
KM401_11540	COG1535	isochorismatase
KM401_11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM401_11550	COG3251	PFAM MbtH domain protein
KM401_11555	COG2814	Major facilitator Superfamily
KM401_11570	COG0776	regulation of translation
KM401_11580	COG2318	DinB family
KM401_11590	COG1115	amino acid carrier protein
KM401_11605	COG2329	Antibiotic biosynthesis monooxygenase
KM401_11610	COG1187	pseudouridine synthase activity
KM401_11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_11630	COG0596	Alpha beta hydrolase
KM401_11635	COG2814	Major facilitator Superfamily
KM401_11655	COG2226	methyltransferase
KM401_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_11735	COG1247	-acetyltransferase
KM401_11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM401_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_11785	COG1278	Cold shock
KM401_11800	COG0010	Belongs to the arginase family
KM401_11805	COG0561	phosphatase activity
KM401_11850	COG0583	DNA-binding transcription factor activity
KM401_11855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM401_11870	COG0583	DNA-binding transcription factor activity
KM401_11875	COG2258	MOSC domain
KM401_11890	COG1132	(ABC) transporter
KM401_11895	COG1132	(ABC) transporter
KM401_11915	COG1396	sequence-specific DNA binding
KM401_11940	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM401_11945	COG1595	DNA-templated transcription, initiation
KM401_11970	COG1649	PFAM Uncharacterised BCR, COG1649
KM401_11995	COG2971	BadF BadG BcrA BcrD
KM401_12000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_12005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM401_12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_12055	COG1309	transcriptional regulator
KM401_12070	COG0577	efflux transmembrane transporter activity
KM401_12070	COG1136	(ABC) transporter
KM401_12075	COG0500	methyltransferase
KM401_12075	COG3615	Tellurite resistance protein tehB
KM401_12085	COG2226	methyltransferase
KM401_12090	COG3961	Belongs to the TPP enzyme family
KM401_12095	COG1846	Transcriptional regulator
KM401_12135	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM401_12150	COG1595	DNA-templated transcription, initiation
KM401_12160	COG0768	penicillin binding
KM401_12170	COG2367	Beta-lactamase
KM401_12175	COG0671	phosphoesterase, PA-phosphatase related
KM401_12180	COG1609	Transcriptional regulator
KM401_12185	COG2814	Major facilitator Superfamily
KM401_12190	COG0673	inositol 2-dehydrogenase activity
KM401_12200	COG1012	belongs to the aldehyde dehydrogenase family
KM401_12215	COG0191	fructose-bisphosphate aldolase activity
KM401_12220	COG3718	enzyme involved in inositol metabolism
KM401_12245	COG0457	Tetratricopeptide repeat
KM401_12250	COG1476	TRANSCRIPTIONal
KM401_12265	COG1876	peptidase activity
KM401_12285	COG1309	transcriptional regulator
KM401_12290	COG0488	(ABC) transporter
KM401_12305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_12320	COG1252	NADH dehydrogenase
KM401_12325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_12340	COG1131	(ABC) transporter
KM401_12350	COG1309	transcriptional regulator
KM401_12365	COG1960	acyl-CoA dehydrogenase activity
KM401_12370	COG0439	Biotin carboxylase
KM401_12375	COG0511	ligase activity, forming carbon-carbon bonds
KM401_12380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM401_12385	COG1024	Enoyl-CoA hydratase
KM401_12390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM401_12395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_12405	COG1247	-acetyltransferase
KM401_12410	COG0572	uridine kinase
KM401_12420	COG2318	DinB family
KM401_12425	COG1686	Belongs to the peptidase S11 family
KM401_12450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM401_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_12515	COG2814	Major facilitator Superfamily
KM401_12535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_12570	COG1063	alcohol dehydrogenase
KM401_12600	COG3773	Cell wall hydrolase
KM401_12610	COG0745	RESPONSE REGULATOR receiver
KM401_12625	COG0488	(ABC) transporter
KM401_12640	COG1136	(ABC) transporter
KM401_12665	COG0460	homoserine dehydrogenase
KM401_12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_12680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM401_12745	COG2124	cytochrome p450
KM401_12780	COG0561	phosphatase activity
KM401_12790	COG5002	protein histidine kinase activity
KM401_12795	COG0768	penicillin binding
KM401_12800	COG1819	glycosyl
KM401_12805	COG1794	racemase activity, acting on amino acids and derivatives
KM401_12815	COG1122	ATPase activity
KM401_12830	COG2205	protein histidine kinase activity
KM401_12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_12845	COG0604	alcohol dehydrogenase
KM401_12850	COG0768	penicillin binding
KM401_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_12895	COG0693	protein deglycase activity
KM401_12925	COG2814	Major facilitator Superfamily
KM401_12940	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_12960	COG0697	spore germination
KM401_12985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_12995	COG2223	nitrite transmembrane transporter activity
KM401_13010	COG2816	NAD+ diphosphatase activity
KM401_13015	COG0592	DNA-directed DNA polymerase activity
KM401_13020	COG1051	belongs to the nudix hydrolase family
KM401_13055	COG3878	Protein conserved in bacteria
KM401_13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM401_13115	COG0322	excinuclease ABC activity
KM401_13155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_13180	COG1011	Hydrolase
KM401_13200	COG0076	glutamate decarboxylase activity
KM401_13215	COG1523	belongs to the glycosyl hydrolase 13 family
KM401_13220	COG3227	Zinc metalloprotease (Elastase)
KM401_13240	COG0201	protein transport
KM401_13250	COG0697	spore germination
KM401_13255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_13285	COG4129	membrane
KM401_13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_13305	COG2959	enzyme of heme biosynthesis
KM401_13325	COG3483	tryptophan 2,3-dioxygenase activity
KM401_13330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM401_13335	COG3844	kynureninase activity
KM401_13340	COG1309	transcriptional regulator
KM401_13370	COG3284	Transcriptional regulator
KM401_13390	COG1349	DNA-binding transcription factor activity
KM401_13410	COG1959	2 iron, 2 sulfur cluster binding
KM401_13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM401_13430	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_13435	COG0022	dehydrogenase e1 component
KM401_13440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_13450	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_13455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_13455	COG0456	acetyltransferase
KM401_13485	COG4176	ABC-type proline glycine betaine transport system permease component
KM401_13490	COG0517	IMP dehydrogenase activity
KM401_13490	COG4175	Glycine betaine
KM401_13515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM401_13520	COG2153	protein acetylation
KM401_13525	COG3397	chitin binding
KM401_13540	COG2205	protein histidine kinase activity
KM401_13565	COG0658	competence protein
KM401_13565	COG2333	competence protein COMEC
KM401_13615	COG3973	AAA domain
KM401_13630	COG2105	PFAM AIG2 family protein
KM401_13635	COG0514	ATP-dependent DNA helicase (RecQ)
KM401_13655	COG4637	Psort location Cytoplasmic, score
KM401_13680	COG3397	chitin binding
KM401_13695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM401_13700	COG1115	amino acid carrier protein
KM401_13705	COG1012	belongs to the aldehyde dehydrogenase family
KM401_13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM401_13720	COG3938	Belongs to the proline racemase family
KM401_13725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_13765	COG0586	Pfam SNARE associated Golgi protein
KM401_13780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM401_13785	COG0519	Catalyzes the synthesis of GMP from XMP
KM401_13790	COG4166	transmembrane transport
KM401_13800	COG4948	Mandelate Racemase Muconate Lactonizing
KM401_13845	COG2936	dipeptidyl-peptidase activity
KM401_13850	COG5002	protein histidine kinase activity
KM401_13890	COG1164	Oligoendopeptidase f
KM401_13905	COG1307	EDD domain protein, DegV family
KM401_13925	COG2814	Major facilitator Superfamily
KM401_13935	COG1664	Polymer-forming cytoskeletal
KM401_13940	COG0789	Transcriptional regulator
KM401_13945	COG4533	DNA binding
KM401_13950	COG0477	Major facilitator Superfamily
KM401_13950	COG2814	Major facilitator Superfamily
KM401_13970	COG2261	transglycosylase associated protein
KM401_13985	COG2226	methyltransferase
KM401_14020	COG0436	Aminotransferase
KM401_14025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM401_14030	COG5146	pantothenate kinase activity
KM401_14050	COG1131	(ABC) transporter
KM401_14095	COG0628	permease
KM401_14105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_14115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_14120	COG1116	anion transmembrane transporter activity
KM401_14140	COG2816	NAD+ diphosphatase activity
KM401_14160	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM401_14185	COG0697	spore germination
KM401_14190	COG2318	DinB family
KM401_14210	COG4912	Dna alkylation repair
KM401_14230	COG0861	Integral membrane protein TerC family
KM401_14235	COG1368	sulfuric ester hydrolase activity
KM401_14240	COG0488	(ABC) transporter
KM401_14250	COG1033	growth of symbiont in host cell
KM401_14250	COG2409	Drug exporters of the RND superfamily
KM401_14255	COG2409	Drug exporters of the RND superfamily
KM401_14255	COG1033	growth of symbiont in host cell
KM401_14260	COG2409	Drug exporters of the RND superfamily
KM401_14260	COG1033	growth of symbiont in host cell
KM401_14265	COG1309	transcriptional regulator
KM401_14280	COG0287	Prephenate dehydrogenase
KM401_14285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM401_14290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM401_14295	COG1605	Chorismate mutase
KM401_14295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM401_14330	COG1388	LysM domain
KM401_14330	COG3584	3D domain protein
KM401_14340	COG1595	DNA-templated transcription, initiation
KM401_14365	COG1879	ABC-type sugar transport system periplasmic component
KM401_14375	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM401_14385	COG2390	Transcriptional regulator
KM401_14420	COG2329	Antibiotic biosynthesis monooxygenase
KM401_14440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_14450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM401_14455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_14460	COG4187	Peptidase family M20/M25/M40
KM401_14465	COG1414	Transcriptional regulator
KM401_14470	COG0833	amino acid
KM401_14475	COG1690	Belongs to the RtcB family
KM401_14480	COG3239	Fatty acid desaturase
KM401_14485	COG1785	Belongs to the alkaline phosphatase family
KM401_14495	COG3655	Transcriptional regulator
KM401_14510	COG4377	Putative membrane peptidase family (DUF2324)
KM401_14520	COG3279	Response regulator of the LytR AlgR family
KM401_14530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_14535	COG0346	lactoylglutathione lyase activity
KM401_14555	COG0714	Associated with various cellular activities
KM401_14580	COG0463	Glycosyl transferase, family 2
KM401_14605	COG0463	Glycosyl transferase, family 2
KM401_14615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM401_14620	COG0753	catalase activity
KM401_14630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM401_14655	COG0714	Associated with various cellular activities
KM401_14665	COG0778	Nitroreductase
KM401_14670	COG1846	Transcriptional regulator
KM401_14705	COG1725	Transcriptional regulator
KM401_14715	COG1136	(ABC) transporter
KM401_14715	COG0577	efflux transmembrane transporter activity
KM401_14740	COG2207	Transcriptional regulator
KM401_14745	COG0456	acetyltransferase
KM401_14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_14785	COG0642	Histidine kinase
KM401_14790	COG0745	RESPONSE REGULATOR receiver
KM401_14795	COG0596	Alpha beta hydrolase
KM401_14825	COG0730	response to heat
KM401_14835	COG0833	amino acid
KM401_14845	COG4335	DNA alkylation repair
KM401_14885	COG0768	penicillin binding
KM401_14895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM401_14925	COG1984	allophanate hydrolase subunit 2
KM401_14930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM401_14935	COG1414	Transcriptional regulator
KM401_14950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_14955	COG0640	Transcriptional regulator
KM401_14965	COG1960	acyl-CoA dehydrogenase activity
KM401_14980	COG3314	Sporulation integral membrane protein YlbJ
KM401_14995	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM401_15010	COG3848	Pyruvate phosphate dikinase
KM401_15010	COG0574	Belongs to the PEP-utilizing enzyme family
KM401_15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_15030	COG5577	PFAM Coat F domain
KM401_15035	COG3403	YqcI/YcgG family
KM401_15040	COG1280	lysine exporter protein (LysE YggA)
KM401_15075	COG1063	alcohol dehydrogenase
KM401_15090	COG1027	Aspartate ammonia-lyase
KM401_15095	COG0252	asparaginase activity
KM401_15100	COG1396	sequence-specific DNA binding
KM401_15110	COG0322	excinuclease ABC activity
KM401_15115	COG0531	amino acid
KM401_15120	COG1114	Component of the transport system for branched-chain amino acids
KM401_15125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_15135	COG0281	malic enzyme
KM401_15150	COG0531	amino acid
KM401_15160	COG0784	Response regulator, receiver
KM401_15170	COG2066	Belongs to the glutaminase family
KM401_15175	COG1115	amino acid carrier protein
KM401_15205	COG0737	Belongs to the 5'-nucleotidase family
KM401_15210	COG0753	catalase activity
KM401_15215	COG2267	carboxylic ester hydrolase activity
KM401_15220	COG1335	isochorismatase
KM401_15240	COG0583	DNA-binding transcription factor activity
KM401_15245	COG1846	Transcriptional regulator
KM401_15285	COG0415	Belongs to the DNA photolyase family
KM401_15290	COG0288	reversible hydration of carbon dioxide
KM401_15300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM401_15305	COG5609	conserved protein (DUF2294)
KM401_15320	COG1575	Belongs to the MenA family. Type 1 subfamily
KM401_15325	COG2267	carboxylic ester hydrolase activity
KM401_15330	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM401_15335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM401_15340	COG1121	(ABC) transporter
KM401_15370	COG0798	PFAM Bile acid sodium symporter
KM401_15375	COG0346	lactoylglutathione lyase activity
KM401_15380	COG0640	Transcriptional regulator
KM401_15395	COG0443	Heat shock 70 kDa protein
KM401_15410	COG1522	sequence-specific DNA binding
KM401_15425	COG0346	lactoylglutathione lyase activity
KM401_15450	COG2169	Transcriptional regulator
KM401_15495	COG2814	Major facilitator Superfamily
KM401_15520	COG0745	RESPONSE REGULATOR receiver
KM401_15525	COG3850	Histidine kinase
KM401_15525	COG5002	protein histidine kinase activity
KM401_15550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM401_15570	COG1476	TRANSCRIPTIONal
KM401_15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_15590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM401_15600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_15605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM401_15620	COG1136	(ABC) transporter
KM401_15625	COG0577	efflux transmembrane transporter activity
KM401_15640	COG5002	protein histidine kinase activity
KM401_15640	COG3850	Histidine kinase
KM401_15650	COG2364	Membrane
KM401_15655	COG1846	Transcriptional regulator
KM401_15665	COG2808	Putative FMN-binding domain
KM401_15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_15675	COG2271	Major facilitator Superfamily
KM401_15680	COG1556	Lactate utilization protein
KM401_15685	COG1139	Iron-sulfur cluster binding protein
KM401_15695	COG0583	DNA-binding transcription factor activity
KM401_15705	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_15730	COG0738	Major facilitator superfamily
KM401_15735	COG0673	inositol 2-dehydrogenase activity
KM401_15740	COG0561	phosphatase activity
KM401_15750	COG1609	Transcriptional regulator
KM401_15755	COG0457	Tetratricopeptide repeat
KM401_15775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_15805	COG0534	Mate efflux family protein
KM401_15825	COG2814	Major facilitator Superfamily
KM401_15830	COG1309	transcriptional regulator
KM401_15845	COG0814	amino acid
KM401_15850	COG1760	l-serine dehydratase
KM401_15855	COG1760	l-serine dehydratase
KM401_15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM401_15870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM401_15880	COG1335	isochorismatase
KM401_15885	COG1522	sequence-specific DNA binding
KM401_15890	COG0531	amino acid
KM401_15905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM401_15925	COG1595	DNA-templated transcription, initiation
KM401_15940	COG0662	Cupin 2, conserved barrel domain protein
KM401_15945	COG2207	Transcriptional regulator
KM401_15945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_15995	COG0477	Major facilitator Superfamily
KM401_16005	COG1846	Transcriptional regulator
KM401_16010	COG2814	Major facilitator Superfamily
KM401_16020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_16025	COG1131	(ABC) transporter
KM401_16045	COG2076	Multidrug Resistance protein
KM401_16050	COG1309	transcriptional regulator
KM401_16060	COG2031	fatty acid transporter
KM401_16070	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_16100	COG1122	ATPase activity
KM401_16105	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM401_16120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM401_16125	COG1288	antiporter activity
KM401_16130	COG2356	endonuclease I
KM401_16145	COG3620	sequence-specific DNA binding
KM401_16150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_16155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM401_16160	COG0124	histidyl-tRNA synthetase
KM401_16175	COG1733	regulation of RNA biosynthetic process
KM401_16180	COG0778	Nitroreductase
KM401_16200	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_16210	COG1131	(ABC) transporter
KM401_16235	COG1011	Hydrolase
KM401_16245	COG2365	Tyrosine phosphatase family
KM401_16270	COG0346	lactoylglutathione lyase activity
KM401_16275	COG1940	carbohydrate kinase activity
KM401_16280	COG0738	Major facilitator superfamily
KM401_16285	COG0110	maltose O-acetyltransferase activity
KM401_16295	COG1136	(ABC) transporter
KM401_16295	COG0577	efflux transmembrane transporter activity
KM401_16310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM401_16315	COG0628	permease
KM401_16335	COG2226	methyltransferase
KM401_16345	COG0477	Major facilitator Superfamily
KM401_16375	COG1253	flavin adenine dinucleotide binding
KM401_16380	COG0789	Transcriptional regulator
KM401_16385	COG0697	spore germination
KM401_16390	COG1357	PFAM Pentapeptide repeats (8 copies)
KM401_16395	COG3813	Protein conserved in bacteria
KM401_16400	COG2706	6-phosphogluconolactonase activity
KM401_16405	COG1070	Carbohydrate kinase
KM401_16415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM401_16420	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM401_16430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM401_16435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM401_16440	COG0604	alcohol dehydrogenase
KM401_16445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_16455	COG0604	alcohol dehydrogenase
KM401_16455	COG3321	synthase
KM401_16460	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_16485	COG0656	L-ascorbic acid biosynthetic process
KM401_16490	COG2814	Major facilitator Superfamily
KM401_16505	COG0346	lactoylglutathione lyase activity
KM401_16510	COG0814	amino acid
KM401_16535	COG1393	Belongs to the ArsC family
KM401_16540	COG1733	regulation of RNA biosynthetic process
KM401_16545	COG2188	Transcriptional regulator
KM401_16555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM401_16560	COG1733	regulation of RNA biosynthetic process
KM401_16565	COG1733	regulation of RNA biosynthetic process
KM401_16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_16600	COG0384	phenazine biosynthesis protein PhzF
KM401_16610	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_16620	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_16630	COG1733	regulation of RNA biosynthetic process
KM401_16665	COG1191	sigma factor activity
KM401_16680	COG1309	transcriptional regulator
KM401_16700	COG3152	Membrane
KM401_16725	COG1151	hydroxylamine reductase activity
KM401_16735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_16740	COG3409	Peptidoglycan-binding domain 1 protein
KM401_16740	COG3757	hydrolase, family 25
KM401_16775	COG2072	flavoprotein involved in K transport
KM401_16810	COG0604	alcohol dehydrogenase
KM401_16815	COG1113	amino acid transport
KM401_16820	COG2814	Major facilitator Superfamily
KM401_16850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_16855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_16875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_16890	COG3739	integral membrane protein
KM401_16895	COG0384	phenazine biosynthesis protein PhzF
KM401_16925	COG0583	DNA-binding transcription factor activity
KM401_16945	COG1193	negative regulation of DNA recombination
KM401_16970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_17000	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_17025	COG0640	Transcriptional regulator
KM401_17030	COG0604	alcohol dehydrogenase
KM401_17050	COG2808	Putative FMN-binding domain
KM401_17055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_17065	COG0385	Bile acid
KM401_17070	COG0277	FAD linked oxidase domain protein
KM401_17100	COG1216	Glycosyl transferase, family 2
KM401_17105	COG1024	Enoyl-CoA hydratase
KM401_17115	COG1285	pathogenesis
KM401_17130	COG2514	catechol 2,3-dioxygenase activity
KM401_17135	COG2720	vancomycin resistance protein
KM401_17175	COG0716	FMN binding
KM401_17205	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_17215	COG0165	Argininosuccinate lyase
KM401_17230	COG4145	pantothenate transmembrane transporter activity
KM401_17240	COG1012	belongs to the aldehyde dehydrogenase family
KM401_17245	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_17255	COG1657	PFAM Prenyltransferase squalene oxidase
KM401_17260	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM401_17265	COG2962	Rard protein
KM401_17270	COG3326	Membrane
KM401_17285	COG0489	protein tyrosine kinase activity
KM401_17295	COG0314	molybdopterin synthase activity
KM401_17300	COG0303	'Molybdopterin
KM401_17305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_17310	COG2116	formate transmembrane transporter activity
KM401_17320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM401_17325	COG5609	conserved protein (DUF2294)
KM401_17330	COG2427	Protein of unknown function (DUF1641)
KM401_17335	COG3383	formate dehydrogenase (NAD+) activity
KM401_17340	COG0697	spore germination
KM401_17380	COG2226	methyltransferase
KM401_17385	COG4166	transmembrane transport
KM401_17390	COG4166	transmembrane transport
KM401_17395	COG4166	transmembrane transport
KM401_17400	COG1301	dicarboxylic acid transport
KM401_17405	COG1316	TRANSCRIPTIONal
KM401_17415	COG1595	DNA-templated transcription, initiation
KM401_17435	COG1131	(ABC) transporter
KM401_17445	COG0673	inositol 2-dehydrogenase activity
KM401_17450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM401_17455	COG0187	DNA topoisomerase II activity
KM401_17460	COG1832	CoA-binding protein
KM401_17465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_17470	COG0745	RESPONSE REGULATOR receiver
KM401_17485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_17490	COG4841	protein insertion into membrane
KM401_17495	COG0824	Thioesterase
KM401_17525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_17535	COG2274	protein secretion by the type I secretion system
KM401_17540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM401_17580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_17595	COG0183	Belongs to the thiolase family
KM401_17600	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_17605	COG1268	BioY protein
KM401_17610	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_17660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_17670	COG5002	protein histidine kinase activity
KM401_17675	COG0400	carboxylic ester hydrolase activity
KM401_17680	COG0346	lactoylglutathione lyase activity
KM401_17685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_17690	COG0069	glutamate synthase activity
KM401_17695	COG1902	pentaerythritol trinitrate reductase activity
KM401_17700	COG1329	Transcriptional regulator
KM401_17705	COG0010	Belongs to the arginase family
KM401_17730	COG2226	methyltransferase
KM401_17785	COG4846	Membrane protein involved in cytochrome C biogenesis
KM401_17790	COG0785	Cytochrome C biogenesis protein
KM401_17800	COG0583	DNA-binding transcription factor activity
KM401_17805	COG1380	Effector of murein hydrolase LrgA
KM401_17810	COG1346	cytolysis
KM401_17835	COG3409	Peptidoglycan-binding domain 1 protein
KM401_17835	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM401_17850	COG1132	(ABC) transporter
KM401_17855	COG1132	(ABC) transporter
KM401_17885	COG3639	organic phosphonate transmembrane transporter activity
KM401_17890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM401_17910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM401_17930	COG1695	Transcriptional regulator
KM401_17965	COG1388	LysM domain
KM401_17965	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM401_17965	COG3409	Peptidoglycan-binding domain 1 protein
KM401_17970	COG4824	toxin secretion phage lysis holin
KM401_18125	COG1595	DNA-templated transcription, initiation
KM401_18170	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM401_18255	COG1396	sequence-specific DNA binding
KM401_18280	COG0174	glutamine synthetase
KM401_18285	COG0789	Transcriptional regulator
KM401_18290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM401_18300	COG2860	membrane
KM401_18310	COG0464	growth
KM401_18340	COG3584	3D domain protein
KM401_18340	COG1388	LysM domain
KM401_18345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM401_18345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM401_18345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_18350	COG1105	Belongs to the carbohydrate kinase PfkB family
KM401_18355	COG1349	DNA-binding transcription factor activity
KM401_18365	COG2322	membrane
KM401_18375	COG1113	amino acid transport
KM401_18390	COG1408	metallophosphoesterase
KM401_18395	COG2116	formate transmembrane transporter activity
KM401_18405	COG2217	Heavy metal translocating P-type atpase
KM401_18410	COG2608	mercury ion transmembrane transporter activity
KM401_18415	COG1937	Protein conserved in bacteria
KM401_18425	COG2819	hydrolase of the alpha beta superfamily
KM401_18430	COG1120	ATPase activity
KM401_18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_18440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_18450	COG0708	Exodeoxyribonuclease III
KM401_18455	COG2169	Transcriptional regulator
KM401_18460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM401_18465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM401_18475	COG2364	Membrane
KM401_18490	COG2267	carboxylic ester hydrolase activity
KM401_18495	COG0346	lactoylglutathione lyase activity
KM401_18500	COG3300	MHYT domain
KM401_18500	COG5001	Diguanylate cyclase
KM401_18515	COG1346	cytolysis
KM401_18520	COG1380	Effector of murein hydrolase LrgA
KM401_18525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_18530	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_18530	COG0596	Alpha beta hydrolase
KM401_18535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_18555	COG1404	Belongs to the peptidase S8 family
KM401_18560	COG3773	Cell wall hydrolase
KM401_18565	COG0562	UDP-galactopyranose mutase
KM401_18570	COG1368	sulfuric ester hydrolase activity
KM401_18575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_18585	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM401_18610	COG1131	(ABC) transporter
KM401_18630	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM401_18635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM401_18640	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM401_18645	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM401_18645	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM401_18655	COG2359	stage V sporulation protein S
KM401_18660	COG1692	metallophosphoesterase
KM401_18685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM401_18690	COG1426	Protein conserved in bacteria
KM401_18705	COG0300	oxidoreductase activity
KM401_18710	COG0612	Peptidase, M16
KM401_18715	COG0612	Peptidase, M16
KM401_18720	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM401_18730	COG3845	ABC transporter
KM401_18735	COG1744	ABC transporter substrate-binding protein PnrA-like
KM401_18740	COG2188	Transcriptional regulator
KM401_18745	COG1674	ftsk spoiiie
KM401_18755	COG0740	serine-type endopeptidase activity
KM401_18760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_18770	COG0527	aspartate kinase activity
KM401_18775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM401_18780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM401_18785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM401_18790	COG1873	PFAM PRC-barrel domain
KM401_18795	COG0612	Peptidase, M16
KM401_18800	COG0726	polysaccharide deacetylase
KM401_18815	COG0196	riboflavin kinase activity
KM401_18820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM401_18830	COG1550	Protein conserved in bacteria
KM401_18840	COG1358	cellular component organization or biogenesis
KM401_18845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM401_18850	COG0195	Participates in both transcription termination and antitermination
KM401_18870	COG0750	zinc metalloprotease
KM401_18880	COG4589	Belongs to the CDS family
KM401_18885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM401_18895	COG0528	UMP kinase activity
KM401_18925	COG4974	Belongs to the 'phage' integrase family
KM401_18935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM401_18945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM401_18985	COG1837	Belongs to the UPF0109 family
KM401_18995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM401_19005	COG0552	protein localization to endoplasmic reticulum
KM401_19010	COG1196	nuclear chromosome segregation
KM401_19020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_19025	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_19030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM401_19045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM401_19050	COG1461	Dihydroxyacetone kinase
KM401_19055	COG1302	Protein conserved in bacteria
KM401_19070	COG1564	THIamine pyrophosphokinase
KM401_19075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM401_19080	COG1162	GTPase activity
KM401_19085	COG0515	serine threonine protein kinase
KM401_19085	COG2815	serine threonine protein kinase
KM401_19090	COG0631	protein serine/threonine phosphatase activity
KM401_19100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM401_19100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM401_19110	COG0242	peptide deformylase activity
KM401_19115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM401_19120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM401_19140	COG1561	YicC-like family, N-terminal region
KM401_19145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM401_19155	COG0006	proline dipeptidase activity
KM401_19170	COG3069	C4-dicarboxylate transmembrane transporter activity
KM401_19235	COG0564	pseudouridine synthase activity
KM401_19255	COG3599	regulation of cell shape
KM401_19260	COG2302	S4 RNA-binding domain
KM401_19265	COG0762	integral membrane protein
KM401_19275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM401_19280	COG1496	oxidoreductase activity
KM401_19285	COG1873	PFAM PRC-barrel domain
KM401_19290	COG1191	sigma factor activity
KM401_19295	COG1191	sigma factor activity
KM401_19305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM401_19310	COG0849	cell division
KM401_19315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM401_19320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM401_19330	COG0772	Belongs to the SEDS family
KM401_19345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM401_19350	COG0768	penicillin binding
KM401_19355	COG0768	penicillin binding
KM401_19360	COG4839	cell division protein FtsL
KM401_19375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM401_19390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM401_19395	COG1399	metal-binding, possibly nucleic acid-binding protein
KM401_19445	COG4824	toxin secretion phage lysis holin
KM401_19530	COG1802	Transcriptional regulator
KM401_19530	COG4626	Terminase
KM401_19555	COG0582	viral genome integration into host DNA
KM401_19620	COG0756	dUTP diphosphatase activity
KM401_19635	COG1191	sigma factor activity
KM401_19660	COG1484	DNA-dependent DNA replication
KM401_19690	COG1396	sequence-specific DNA binding
KM401_19705	COG1396	sequence-specific DNA binding
KM401_19720	COG0582	viral genome integration into host DNA
KM401_19730	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM401_19735	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM401_19740	COG3314	Sporulation integral membrane protein YlbJ
KM401_19750	COG0742	ribosomal rna small subunit methyltransferase
KM401_19765	COG3679	Belongs to the UPF0342 family
KM401_19770	COG0406	alpha-ribazole phosphatase activity
KM401_19785	COG2340	Cysteine-rich secretory protein family
KM401_19800	COG3336	cytochrome c oxidase
KM401_19835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM401_19840	COG0772	Belongs to the SEDS family
KM401_19850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM401_19855	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM401_19865	COG4896	Protein conserved in bacteria
KM401_19880	COG1217	gtp-binding protein TYPA
KM401_19890	COG0483	inositol monophosphate 1-phosphatase activity
KM401_19910	COG1982	Orn Lys Arg decarboxylase major
KM401_19955	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_19960	COG0022	dehydrogenase e1 component
KM401_19965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_19975	COG0242	peptide deformylase activity
KM401_19980	COG0561	phosphatase activity
KM401_19990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_19995	COG0569	domain protein
KM401_20015	COG0583	DNA-binding transcription factor activity
KM401_20020	COG0517	IMP dehydrogenase activity
KM401_20030	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM401_20040	COG4703	Protein of unknown function (DUF1797)
KM401_20055	COG2200	EAL domain
KM401_20060	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_20065	COG1408	metallophosphoesterase
KM401_20075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM401_20110	COG2814	Major facilitator Superfamily
KM401_20130	COG3209	COG3209 Rhs family protein
KM401_20140	COG2205	protein histidine kinase activity
KM401_20150	COG0436	Aminotransferase
KM401_20155	COG1609	Transcriptional regulator
KM401_20160	COG3833	ABC-type maltose transport systems, permease component
KM401_20165	COG1175	transmembrane transport
KM401_20170	COG2182	Extracellular solute-binding protein
KM401_20180	COG0366	Alpha amylase catalytic
KM401_20185	COG3842	ATPase activity
KM401_20225	COG0183	Belongs to the thiolase family
KM401_20260	COG1695	Transcriptional regulator
KM401_20265	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_20275	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM401_20285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM401_20290	COG0436	Aminotransferase
KM401_20310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM401_20330	COG2199	diguanylate cyclase activity
KM401_20335	COG0778	Nitroreductase
KM401_20360	COG1263	PTS System
KM401_20360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_20360	COG2190	(PTS) system
KM401_20365	COG3711	transcriptional antiterminator
KM401_20375	COG2188	Transcriptional regulator
KM401_20385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM401_20410	COG1547	Domain of unknown function (DUF309)
KM401_20415	COG0456	acetyltransferase
KM401_20420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM401_20425	COG4086	secreted protein
KM401_20430	COG0561	phosphatase activity
KM401_20435	COG0697	spore germination
KM401_20450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_20475	COG0733	neurotransmitter:sodium symporter activity
KM401_20495	COG1686	Belongs to the peptidase S11 family
KM401_20500	COG1725	Transcriptional regulator
KM401_20505	COG1131	(ABC) transporter
KM401_20520	COG1846	Transcriptional regulator
KM401_20535	COG0598	Magnesium transport protein CorA
KM401_20560	COG4974	Belongs to the 'phage' integrase family
KM401_20570	COG0735	belongs to the Fur family
KM401_20575	COG1300	Membrane
KM401_20595	COG0667	Aldo Keto reductase
KM401_20600	COG0656	L-ascorbic acid biosynthetic process
KM401_20605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_20605	COG0456	acetyltransferase
KM401_20615	COG4085	toxin activity
KM401_20615	COG0737	Belongs to the 5'-nucleotidase family
KM401_20615	COG1525	nuclease
KM401_20625	COG0596	Alpha beta hydrolase
KM401_20630	COG2056	Na+-H+ antiporter family
KM401_20635	COG1609	Transcriptional regulator
KM401_20640	COG0456	acetyltransferase
KM401_20645	COG1073	alpha beta
KM401_20660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM401_20660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM401_20665	COG0307	riboflavin synthase, alpha
KM401_20690	COG4106	trans-aconitate 2-methyltransferase activity
KM401_20695	COG2226	methyltransferase
KM401_20695	COG1073	alpha beta
KM401_20710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_20720	COG1757	Na H antiporter
KM401_20725	COG0737	Belongs to the 5'-nucleotidase family
KM401_20735	COG1522	sequence-specific DNA binding
KM401_20755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM401_20765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM401_20780	COG0300	oxidoreductase activity
KM401_20790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_20795	COG1760	l-serine dehydratase
KM401_20800	COG1760	l-serine dehydratase
KM401_20820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_20830	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM401_20835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_20850	COG1376	ErfK ybiS ycfS ynhG family protein
KM401_20855	COG4129	membrane
KM401_20860	COG1126	abc transporter atp-binding protein
KM401_20865	COG0765	amino acid transport
KM401_20870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_20890	COG0772	Belongs to the SEDS family
KM401_20895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_20900	COG0022	dehydrogenase e1 component
KM401_20905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_20910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM401_20925	COG0280	phosphate acetyltransferase
KM401_20930	COG3829	transcription factor binding
KM401_20930	COG3290	protein histidine kinase activity
KM401_20940	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_20945	COG3093	addiction module antidote protein HigA
KM401_20955	COG0745	RESPONSE REGULATOR receiver
KM401_20960	COG0750	zinc metalloprotease
KM401_20965	COG0497	DNA recombination
KM401_20975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM401_20985	COG0142	geranyltranstransferase activity
KM401_21010	COG1302	Protein conserved in bacteria
KM401_21015	COG0439	Biotin carboxylase
KM401_21020	COG0511	ligase activity, forming carbon-carbon bonds
KM401_21065	COG3854	ATPases associated with a variety of cellular activities
KM401_21090	COG0006	proline dipeptidase activity
KM401_21105	COG3872	metal-dependent enzyme
KM401_21115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM401_21135	COG0095	Lipoate-protein ligase
KM401_21140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_21145	COG1609	Transcriptional regulator
KM401_21155	COG2076	Multidrug Resistance protein
KM401_21160	COG2076	Multidrug Resistance protein
KM401_21200	COG1725	Transcriptional regulator
KM401_21230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_21285	COG4970	Tfp pilus assembly protein FimT
KM401_21295	COG1459	type II secretion system
KM401_21300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM401_21350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM401_21355	COG1410	methionine synthase
KM401_21355	COG0646	methionine synthase
KM401_21360	COG0646	methionine synthase
KM401_21360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM401_21365	COG0626	cystathionine gamma-synthase activity
KM401_21370	COG0626	cystathionine gamma-synthase activity
KM401_21390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_21400	COG1940	carbohydrate kinase activity
KM401_21405	COG4483	Protein conserved in bacteria
KM401_21410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM401_21415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM401_21420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM401_21425	COG0704	Plays a role in the regulation of phosphate uptake
KM401_21435	COG0581	inorganic phosphate transmembrane transporter activity
KM401_21440	COG0573	inorganic phosphate transmembrane transporter activity
KM401_21445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM401_21450	COG0768	penicillin binding
KM401_21455	COG0477	Major facilitator Superfamily
KM401_21460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_21485	COG0735	belongs to the Fur family
KM401_21490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM401_21495	COG1121	(ABC) transporter
KM401_21500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_21530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM401_21535	COG2384	SAM-dependent methyltransferase
KM401_21540	COG2010	Cytochrome c
KM401_21545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM401_21550	COG0358	DNA primase activity
KM401_21565	COG0517	IMP dehydrogenase activity
KM401_21580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM401_21585	COG0295	cytidine deaminase activity
KM401_21590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM401_21600	COG1480	7TM receptor with intracellular HD hydrolase
KM401_21605	COG1702	phosphate starvation-inducible protein PhoH
KM401_21620	COG1610	YqeY-like protein
KM401_21625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM401_21630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM401_21635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM401_21665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM401_21670	COG1733	regulation of RNA biosynthetic process
KM401_21695	COG1466	dna polymerase III delta subunit
KM401_21705	COG0658	competence protein
KM401_21705	COG2333	competence protein COMEC
KM401_21710	COG2131	deaminase
KM401_21715	COG1596	polysaccharide export
KM401_21715	COG1555	photosystem II stabilization
KM401_21720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_21725	COG2226	methyltransferase
KM401_21730	COG0799	negative regulation of ribosome biogenesis
KM401_21735	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM401_21745	COG1534	Rna-binding protein
KM401_21755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM401_21760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM401_21785	COG1595	DNA-templated transcription, initiation
KM401_21795	COG0778	Nitroreductase
KM401_21800	COG2357	RelA SpoT domain protein
KM401_21810	COG1785	Belongs to the alkaline phosphatase family
KM401_21820	COG2267	carboxylic ester hydrolase activity
KM401_21855	COG1404	Belongs to the peptidase S8 family
KM401_21860	COG3186	Phenylalanine-4-hydroxylase
KM401_21875	COG2259	Doxx family
KM401_21915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_21925	COG1012	belongs to the aldehyde dehydrogenase family
KM401_21925	COG1454	alcohol dehydrogenase
KM401_21930	COG0626	cystathionine gamma-synthase activity
KM401_21935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_21960	COG0768	penicillin binding
KM401_21975	COG0826	peptidase U32
KM401_21980	COG0826	peptidase U32
KM401_21985	COG4122	O-methyltransferase activity
KM401_21990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM401_22010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_22020	COG0628	permease
KM401_22040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM401_22050	COG0482	sulfurtransferase activity
KM401_22055	COG1104	cysteine desulfurase activity
KM401_22060	COG1959	2 iron, 2 sulfur cluster binding
KM401_22065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM401_22075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM401_22100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM401_22110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM401_22110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM401_22115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM401_22120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM401_22120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM401_22130	COG2244	polysaccharide biosynthetic process
KM401_22135	COG2323	membrane
KM401_22145	COG1862	Preprotein translocase
KM401_22175	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM401_22185	COG0697	spore germination
KM401_22190	COG0697	spore germination
KM401_22195	COG0640	Transcriptional regulator
KM401_22220	COG0157	Belongs to the NadC ModD family
KM401_22225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM401_22230	COG1104	cysteine desulfurase activity
KM401_22235	COG1827	regulation of RNA biosynthetic process
KM401_22240	COG2258	MOSC domain
KM401_22245	COG0077	Prephenate dehydratase
KM401_22250	COG0577	efflux transmembrane transporter activity
KM401_22255	COG0577	efflux transmembrane transporter activity
KM401_22260	COG1136	(ABC) transporter
KM401_22270	COG0745	RESPONSE REGULATOR receiver
KM401_22275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM401_22280	COG3290	protein histidine kinase activity
KM401_22290	COG2868	ribosomal protein
KM401_22300	COG1530	ribonuclease E activity
KM401_22305	COG1994	Peptidase M50
KM401_22310	COG0739	heme binding
KM401_22315	COG2894	cell division
KM401_22335	COG1077	Cell shape determining protein MreB Mrl
KM401_22355	COG0285	dihydrofolate synthase activity
KM401_22360	COG0525	valine-tRNA ligase activity
KM401_22370	COG1388	LysM domain
KM401_22380	COG0113	porphobilinogen synthase activity
KM401_22385	COG1587	Uroporphyrinogen-III synthase
KM401_22395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM401_22405	COG1846	Transcriptional regulator
KM401_22410	COG1764	response to oxidative stress
KM401_22425	COG0470	DNA polymerase III
KM401_22425	COG1067	ATP-dependent peptidase activity
KM401_22470	COG0622	Phosphoesterase
KM401_22485	COG5401	PFAM Sporulation and spore germination
KM401_22505	COG1309	transcriptional regulator
KM401_22520	COG2197	response regulator
KM401_22525	COG2233	PERMEase
KM401_22535	COG0402	S-adenosylhomocysteine deaminase activity
KM401_22540	COG0402	S-adenosylhomocysteine deaminase activity
KM401_22550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_22560	COG0444	Belongs to the ABC transporter superfamily
KM401_22565	COG4608	Belongs to the ABC transporter superfamily
KM401_22570	COG3275	phosphorelay sensor kinase activity
KM401_22575	COG3279	Response regulator of the LytR AlgR family
KM401_22590	COG1983	PspC domain protein
KM401_22595	COG1396	sequence-specific DNA binding
KM401_22600	COG0697	spore germination
KM401_22610	COG1959	2 iron, 2 sulfur cluster binding
KM401_22615	COG1668	transmembrane transport
KM401_22620	COG4152	abc transporter atp-binding protein
KM401_22625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM401_22635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM401_22640	COG1876	peptidase activity
KM401_22645	COG0824	Thioesterase
KM401_22650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM401_22655	COG1053	succinate dehydrogenase
KM401_22660	COG2009	succinate dehydrogenase
KM401_22665	COG1719	4-vinyl reductase, 4VR
KM401_22675	COG3118	belongs to the thioredoxin family
KM401_22680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM401_22685	COG2086	electron transfer activity
KM401_22690	COG1024	Enoyl-CoA hydratase
KM401_22695	COG1309	transcriptional regulator
KM401_22700	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_22720	COG2318	DinB family
KM401_22750	COG1131	(ABC) transporter
KM401_22755	COG2205	protein histidine kinase activity
KM401_22760	COG0745	RESPONSE REGULATOR receiver
KM401_22770	COG4895	conserved protein (DUF2196)
KM401_22775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM401_22790	COG4509	Sortase family
KM401_22795	COG1120	ATPase activity
KM401_22810	COG5386	Cell surface protein
KM401_22820	COG5386	Cell surface protein
KM401_22825	COG1114	Component of the transport system for branched-chain amino acids
KM401_22830	COG1187	pseudouridine synthase activity
KM401_22840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM401_22840	COG1796	DNA polymerase
KM401_22845	COG1286	toxin biosynthetic process
KM401_22890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM401_22900	COG1418	mRNA catabolic process
KM401_22925	COG2814	Major facilitator Superfamily
KM401_22930	COG1566	PFAM secretion protein HlyD family protein
KM401_22935	COG1309	transcriptional regulator
KM401_22940	COG1363	Peptidase, m42
KM401_22965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_22975	COG1484	DNA-dependent DNA replication
KM401_22980	COG3611	Membrane attachment protein
KM401_22990	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM401_22995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM401_23000	COG0237	dephospho-CoA kinase activity
KM401_23005	COG1971	Probably functions as a manganese efflux pump
KM401_23015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_23015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_23020	COG5002	protein histidine kinase activity
KM401_23025	COG0745	RESPONSE REGULATOR receiver
KM401_23045	COG0538	isocitrate dehydrogenase activity
KM401_23050	COG0372	Belongs to the citrate synthase family
KM401_23060	COG0628	permease
KM401_23065	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM401_23090	COG1725	Transcriptional regulator
KM401_23095	COG0281	malic enzyme
KM401_23100	COG0587	DNA-directed DNA polymerase activity
KM401_23115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM401_23135	COG4109	DRTGG domain
KM401_23150	COG0006	proline dipeptidase activity
KM401_23185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_23190	COG0662	Cupin 2, conserved barrel domain protein
KM401_23200	COG1476	TRANSCRIPTIONal
KM401_23215	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_23220	COG0589	response to stress
KM401_23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_23280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM401_23285	COG0827	DNA restriction-modification system
KM401_23290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM401_23295	COG3874	Sporulation protein YtfJ
KM401_23310	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM401_23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_23335	COG1104	cysteine desulfurase activity
KM401_23345	COG0583	DNA-binding transcription factor activity
KM401_23350	COG0697	spore germination
KM401_23360	COG1956	GAF domain-containing protein
KM401_23365	COG0626	cystathionine gamma-synthase activity
KM401_23395	COG1595	DNA-templated transcription, initiation
KM401_23405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_23410	COG0454	-acetyltransferase
KM401_23415	COG0517	IMP dehydrogenase activity
KM401_23420	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM401_23430	COG0745	RESPONSE REGULATOR receiver
KM401_23440	COG0666	response to abiotic stimulus
KM401_23475	COG1609	Transcriptional regulator
KM401_23480	COG4851	CamS sex pheromone cAM373 precursor
KM401_23485	COG3118	belongs to the thioredoxin family
KM401_23495	COG2309	aminopeptidase activity
KM401_23515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_23530	COG1674	ftsk spoiiie
KM401_23540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_23545	COG4848	Belongs to the UPF0354 family
KM401_23550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_23555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM401_23560	COG1363	Peptidase, m42
KM401_23570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_23585	COG0510	thiamine kinase activity
KM401_23590	COG1523	belongs to the glycosyl hydrolase 13 family
KM401_23605	COG1349	DNA-binding transcription factor activity
KM401_23610	COG1187	pseudouridine synthase activity
KM401_23615	COG2244	polysaccharide biosynthetic process
KM401_23620	COG2081	HI0933 family
KM401_23625	COG2814	Major facilitator Superfamily
KM401_23635	COG3832	glyoxalase III activity
KM401_23655	COG1329	Transcriptional regulator
KM401_23665	COG4975	Glucose uptake
KM401_23680	COG0314	molybdopterin synthase activity
KM401_23685	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM401_23690	COG0303	'Molybdopterin
KM401_23700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_23725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_23735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM401_23780	COG2814	Major facilitator Superfamily
KM401_23785	COG0475	glutathione-regulated potassium exporter activity
KM401_23790	COG0490	domain, Protein
KM401_23795	COG0582	viral genome integration into host DNA
KM401_23805	COG1136	(ABC) transporter
KM401_23825	COG1242	4 iron, 4 sulfur cluster binding
KM401_23830	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM401_23835	COG1131	(ABC) transporter
KM401_23845	COG1794	racemase activity, acting on amino acids and derivatives
KM401_23865	COG2267	carboxylic ester hydrolase activity
KM401_23870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM401_23875	COG0671	phosphoesterase, PA-phosphatase related
KM401_23880	COG0438	transferase activity, transferring glycosyl groups
KM401_23890	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM401_23945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM401_23950	COG5002	protein histidine kinase activity
KM401_23955	COG4191	Histidine kinase
KM401_23960	COG2267	carboxylic ester hydrolase activity
KM401_23980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_23985	COG1116	anion transmembrane transporter activity
KM401_23990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_24015	COG0494	nUDIX hydrolase
KM401_24045	COG0288	reversible hydration of carbon dioxide
KM401_24050	COG1271	oxidase subunit
KM401_24055	COG1294	oxidase, subunit
KM401_24075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_24100	COG1842	Phage shock protein A
KM401_24130	COG5002	protein histidine kinase activity
KM401_24135	COG0745	RESPONSE REGULATOR receiver
KM401_24165	COG1597	lipid kinase activity
KM401_24200	COG0586	Pfam SNARE associated Golgi protein
KM401_24210	COG0577	efflux transmembrane transporter activity
KM401_24215	COG1136	(ABC) transporter
KM401_24220	COG2207	Transcriptional regulator
KM401_24220	COG3708	Transcriptional regulator
KM401_24225	COG0745	RESPONSE REGULATOR receiver
KM401_24230	COG2205	protein histidine kinase activity
KM401_24235	COG0577	efflux transmembrane transporter activity
KM401_24245	COG0577	efflux transmembrane transporter activity
KM401_24250	COG1136	(ABC) transporter
KM401_24270	COG2188	Transcriptional regulator
KM401_24290	COG3964	amidohydrolase
KM401_24320	COG4948	Mandelate Racemase Muconate Lactonizing
KM401_24330	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM401_24335	COG0596	Alpha beta hydrolase
KM401_24340	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM401_24345	COG1169	isochorismate synthase
KM401_24350	COG1575	Belongs to the MenA family. Type 1 subfamily
KM401_24355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM401_24375	COG0058	SHG alpha-glucan phosphorylase activity
KM401_24380	COG0297	glycogen (starch) synthase activity
KM401_24385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM401_24505	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM401_24540	COG1285	pathogenesis
KM401_24545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM401_24555	COG0166	Belongs to the GPI family
KM401_24560	COG2155	Conserved Protein
KM401_24565	COG1098	S1 RNA binding domain
KM401_24570	COG0436	Aminotransferase
KM401_24575	COG1522	sequence-specific DNA binding
KM401_24580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM401_24585	COG2267	carboxylic ester hydrolase activity
KM401_24595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM401_24615	COG5018	Exonuclease
KM401_24620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_24640	COG2050	protein possibly involved in aromatic compounds catabolism
KM401_24650	COG1268	BioY protein
KM401_24660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM401_24665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM401_24680	COG3584	3D domain protein
KM401_24695	COG1252	NADH dehydrogenase
KM401_24710	COG3708	Transcriptional regulator
KM401_24725	COG1683	Conserved Protein
KM401_24745	COG0316	Belongs to the HesB IscA family
KM401_24760	COG1252	NADH dehydrogenase
KM401_24775	COG0390	transport system, permease component
KM401_24780	COG2824	Alkylphosphonate utilization operon protein PhnA
KM401_24820	COG4837	Protein of unknown function (DUF1462)
KM401_24825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM401_24835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_24840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM401_24850	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_24855	COG0647	UMP catabolic process
KM401_24865	COG2445	Protein of unknown function DUF86
KM401_24870	COG1494	fructose-1,6-bisphosphatase
KM401_24885	COG4470	Protein conserved in bacteria
KM401_24895	COG0789	Transcriptional regulator
KM401_24900	COG4377	Putative membrane peptidase family (DUF2324)
KM401_24925	COG0739	heme binding
KM401_24935	COG3377	Domain of unknown function (DUF1805)
KM401_24940	COG0737	Belongs to the 5'-nucleotidase family
KM401_24945	COG1695	Transcriptional regulator
KM401_24955	COG0719	Fe-S assembly protein
KM401_24960	COG0822	iron-sulfur transferase activity
KM401_24965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM401_24970	COG0719	Fe-S assembly protein
KM401_24975	COG0396	ATPase activity
KM401_24980	COG1464	Belongs to the NlpA lipoprotein family
KM401_24985	COG1464	Belongs to the NlpA lipoprotein family
KM401_24990	COG2011	ABC-type metal ion transport system permease component
KM401_24995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_25005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_25010	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM401_25020	COG1393	Belongs to the ArsC family
KM401_25065	COG0039	L-malate dehydrogenase activity
KM401_25085	COG1309	transcriptional regulator
KM401_25090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_25095	COG1960	acyl-CoA dehydrogenase activity
KM401_25100	COG0183	Belongs to the thiolase family
KM401_25105	COG1024	Enoyl-CoA hydratase
KM401_25105	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM401_25115	COG1686	Belongs to the peptidase S11 family
KM401_25130	COG0011	TIGRFAM Protein of
KM401_25135	COG0840	transmembrane signaling receptor activity
KM401_25155	COG2814	Major facilitator Superfamily
KM401_25160	COG0531	amino acid
KM401_25170	COG0706	membrane insertase activity
KM401_25180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_25215	COG0586	Pfam SNARE associated Golgi protein
KM401_25225	COG1376	ErfK ybiS ycfS ynhG family protein
KM401_25230	COG0745	RESPONSE REGULATOR receiver
KM401_25235	COG5002	protein histidine kinase activity
KM401_25260	COG2151	metal-sulfur cluster biosynthetic enzyme
KM401_25265	COG3227	Zinc metalloprotease (Elastase)
KM401_25270	COG1741	Belongs to the pirin family
KM401_25285	COG0475	glutathione-regulated potassium exporter activity
KM401_25290	COG0490	domain, Protein
KM401_25295	COG1115	amino acid carrier protein
KM401_25300	COG0783	Belongs to the Dps family
KM401_25315	COG1611	Belongs to the LOG family
KM401_25335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_25340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_25345	COG1115	amino acid carrier protein
KM401_25350	COG1115	amino acid carrier protein
KM401_25355	COG2910	NAD(P)H-binding
KM401_25370	COG0656	L-ascorbic acid biosynthetic process
KM401_25375	COG2814	Major facilitator Superfamily
KM401_25380	COG1733	regulation of RNA biosynthetic process
KM401_25390	COG1252	NADH dehydrogenase
KM401_25395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM401_25400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM401_25410	COG0840	transmembrane signaling receptor activity
KM401_25410	COG3290	protein histidine kinase activity
KM401_25420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM401_25425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM401_25440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_25495	COG0557	exoribonuclease II activity
KM401_25500	COG1647	Serine aminopeptidase, S33
KM401_25505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM401_25510	COG1346	cytolysis
KM401_25615	COG4695	Portal protein
KM401_25640	COG4974	Belongs to the 'phage' integrase family
KM401_25650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM401_25655	COG0149	triose-phosphate isomerase activity
KM401_25665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM401_25680	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM401_25705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_25720	COG2323	membrane
KM401_25725	COG0740	serine-type endopeptidase activity
KM401_25730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_25740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM401_25750	COG1051	belongs to the nudix hydrolase family
KM401_25760	COG0492	ferredoxin-NADP+ reductase activity
KM401_25765	COG0457	Tetratricopeptide repeat
KM401_25770	COG0110	maltose O-acetyltransferase activity
KM401_25790	COG1950	PFAM Membrane protein of
KM401_25800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_25805	COG0556	nucleotide-excision repair
KM401_25825	COG0789	Transcriptional regulator
KM401_25850	COG2855	membrane
KM401_25855	COG0583	DNA-binding transcription factor activity
KM401_25865	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM401_25870	COG0488	(ABC) transporter
KM401_25880	COG1132	(ABC) transporter
KM401_25885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_25890	COG0793	Belongs to the peptidase S41A family
KM401_25890	COG3409	Peptidoglycan-binding domain 1 protein
KM401_25895	COG2177	Part of the ABC transporter FtsEX involved in
KM401_25900	COG2884	Cell division ATP-binding protein ftsE
KM401_25915	COG0653	protein targeting
KM401_25920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM401_25925	COG1278	Cold shock
KM401_25930	COG1040	competence protein
KM401_25935	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM401_25940	COG1388	LysM domain
KM401_25940	COG0791	NLP P60 protein
KM401_25945	COG1733	regulation of RNA biosynthetic process
KM401_25950	COG1307	EDD domain protein, DegV family
KM401_25955	COG1739	Uncharacterized protein family UPF0029
KM401_25960	COG1316	TRANSCRIPTIONal
KM401_25965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM401_25970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM401_25975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM401_25985	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM401_25985	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM401_26000	COG3394	polysaccharide catabolic process
KM401_26005	COG1486	melibiose metabolic process
KM401_26010	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_26015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_26025	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM401_26030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM401_26035	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_26045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_26050	COG1301	dicarboxylic acid transport
KM401_26060	COG0346	lactoylglutathione lyase activity
KM401_26065	COG1511	domain protein
KM401_26070	COG0583	DNA-binding transcription factor activity
KM401_26075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM401_26090	COG1271	oxidase subunit
KM401_26095	COG1294	oxidase, subunit
KM401_26100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_26120	COG2389	metal-binding protein
KM401_26130	COG1368	sulfuric ester hydrolase activity
KM401_26145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_26155	COG1215	transferase activity, transferring glycosyl groups
KM401_26160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_26165	COG3584	3D domain protein
KM401_26165	COG1388	LysM domain
KM401_26190	COG4715	Zinc finger, swim domain protein
KM401_26195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_26235	COG0577	efflux transmembrane transporter activity
KM401_26240	COG1136	(ABC) transporter
KM401_26275	COG5002	protein histidine kinase activity
KM401_26280	COG0745	RESPONSE REGULATOR receiver
KM401_26285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM401_26300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM401_26305	COG1134	teichoic acid transport
KM401_26310	COG1682	transport, permease protein
KM401_26315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM401_26360	COG1609	Transcriptional regulator
KM401_26375	COG0739	heme binding
KM401_26395	COG2385	sporulation resulting in formation of a cellular spore
KM401_26410	COG4836	Membrane
KM401_26415	COG1007	ATP synthesis coupled electron transport
KM401_26420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM401_26425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM401_26435	COG0839	Belongs to the complex I subunit 6 family
KM401_26450	COG0649	NAD binding
KM401_26455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM401_26470	COG3300	MHYT domain
KM401_26470	COG5001	Diguanylate cyclase
KM401_26520	COG0356	it plays a direct role in the translocation of protons across the membrane
KM401_26555	COG0698	ribose 5-phosphate isomerase
KM401_26565	COG2190	(PTS) system
KM401_26570	COG2259	Doxx family
KM401_26575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM401_26590	COG0009	L-threonylcarbamoyladenylate synthase
KM401_26605	COG2890	protein-(glutamine-N5) methyltransferase activity
KM401_26625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM401_26630	COG1494	fructose-1,6-bisphosphatase
KM401_26650	COG4821	SIS domain
KM401_26660	COG3343	RNA polymerase activity
KM401_26670	COG1960	acyl-CoA dehydrogenase activity
KM401_26675	COG1960	acyl-CoA dehydrogenase activity
KM401_26680	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM401_26685	COG0183	Belongs to the thiolase family
KM401_26690	COG0247	lactate metabolic process
KM401_26690	COG2181	nitrate reductase activity
KM401_26695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_26705	COG5001	Diguanylate cyclase
KM401_26705	COG3300	MHYT domain
KM401_26725	COG2197	response regulator
KM401_26730	COG4585	Histidine kinase
KM401_26735	COG0842	Transport permease protein
KM401_26740	COG1131	(ABC) transporter
KM401_26745	COG0024	Methionine aminopeptidase
KM401_26755	COG2234	aminopeptidase activity
KM401_26775	COG1595	DNA-templated transcription, initiation
KM401_26780	COG0018	arginyl-trna synthetase
KM401_26785	COG4506	Protein conserved in bacteria
KM401_26790	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_26805	COG0010	Belongs to the arginase family
KM401_26815	COG2814	Major facilitator Superfamily
KM401_26820	COG0789	Transcriptional regulator
KM401_26825	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_26830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_26840	COG1994	Peptidase M50
KM401_26850	COG1078	dGTPase activity
KM401_26855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_26860	COG1120	ATPase activity
KM401_26865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_26890	COG0095	Lipoate-protein ligase
KM401_26895	COG0280	phosphate acetyltransferase
KM401_26910	COG3773	Cell wall hydrolase
KM401_26920	COG2363	Small membrane protein
KM401_26930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM401_26935	COG2233	PERMEase
KM401_26940	COG0561	phosphatase activity
KM401_26945	COG2814	Major facilitator Superfamily
KM401_26955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_26960	COG1131	(ABC) transporter
KM401_26965	COG2755	lipolytic protein G-D-S-L family
KM401_26970	COG1609	Transcriptional regulator
KM401_26980	COG0460	homoserine dehydrogenase
KM401_26990	COG2873	o-acetylhomoserine
KM401_27000	COG1011	Hydrolase
KM401_27005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM401_27015	COG2197	response regulator
KM401_27025	COG0351	phosphomethylpyrimidine kinase
KM401_27030	COG3706	GGDEF domain
KM401_27035	COG2879	small protein
KM401_27040	COG1966	Carbon starvation protein
KM401_27045	COG3279	Response regulator of the LytR AlgR family
KM401_27050	COG0477	Major facilitator Superfamily
KM401_27075	COG0840	transmembrane signaling receptor activity
KM401_27085	COG1607	acyl-coa hydrolase
KM401_27100	COG0488	(ABC) transporter
KM401_27120	COG0463	Glycosyl transferase, family 2
KM401_27125	COG1309	transcriptional regulator
KM401_27130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM401_27135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_27135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_27140	COG0628	permease
KM401_27155	COG3279	Response regulator of the LytR AlgR family
KM401_27160	COG3275	phosphorelay sensor kinase activity
KM401_27165	COG2814	Major facilitator Superfamily
KM401_27170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_27175	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM401_27180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_27200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM401_27205	COG1272	protein, Hemolysin III
KM401_27225	COG0516	GMP reductase activity
KM401_27230	COG1164	Oligoendopeptidase f
KM401_27250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_27255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM401_27260	COG4853	Protein conserved in bacteria
KM401_27265	COG4863	YycH protein
KM401_27270	COG5002	protein histidine kinase activity
KM401_27275	COG0745	RESPONSE REGULATOR receiver
KM401_27305	COG0305	Participates in initiation and elongation during chromosome replication
KM401_27315	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM401_27320	COG4241	membrane
KM401_27330	COG0629	single-stranded DNA binding
KM401_27340	COG0012	GTP binding
KM401_27345	COG4481	Protein conserved in bacteria
KM401_27350	COG0668	transmembrane transport
KM401_27360	COG1475	DNA binding
KM401_27365	COG1192	Involved in chromosome partitioning
KM401_27390	COG1847	R3H domain protein
KM401_27395	COG0706	membrane insertase activity
KM401_27405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM401_27560	COG0741	lytic transglycosylase activity
KM401_27560	COG0791	NLP P60 protein
KM401_27625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM401_27685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_27695	COG4166	transmembrane transport
KM401_27730	COG1280	lysine exporter protein (LysE YggA)
KM401_27755	COG0681	Belongs to the peptidase S26 family
KM401_27830	COG1309	transcriptional regulator
KM401_27835	COG1683	Conserved Protein
KM401_27880	COG1192	Involved in chromosome partitioning