locus-tag	class	description
M1C60_00010	COG0592	DNA-directed DNA polymerase activity
M1C60_00015	COG2501	S4 domain
M1C60_00025	COG0187	DNA topoisomerase II activity
M1C60_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1C60_00065	COG0516	GMP reductase activity
M1C60_00065	COG0517	IMP dehydrogenase activity
M1C60_00070	COG1686	Belongs to the peptidase S11 family
M1C60_00100	COG1428	Deoxynucleoside kinase
M1C60_00105	COG1428	Deoxynucleoside kinase
M1C60_00110	COG1335	isochorismatase
M1C60_00115	COG0590	tRNA wobble adenosine to inosine editing
M1C60_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1C60_00180	COG1982	Orn Lys Arg decarboxylase major
M1C60_00190	COG0470	DNA polymerase III
M1C60_00195	COG1774	PSP1 C-terminal conserved region
M1C60_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M1C60_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M1C60_00220	COG2002	toxin-antitoxin pair type II binding
M1C60_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_00230	COG0084	hydrolase, TatD family'
M1C60_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1C60_00250	COG4466	Protein conserved in bacteria
M1C60_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M1C60_00270	COG0251	oxidation-reduction process
M1C60_00305	COG2002	toxin-antitoxin pair type II binding
M1C60_00315	COG3956	TIGRFAM MazG family protein
M1C60_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1C60_00340	COG1098	S1 RNA binding domain
M1C60_00355	COG2208	phosphoserine phosphatase activity
M1C60_00360	COG0037	tRNA processing
M1C60_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M1C60_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1C60_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1C60_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
M1C60_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1C60_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M1C60_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1C60_00420	COG1396	sequence-specific DNA binding
M1C60_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1C60_00455	COG3880	PFAM UvrB UvrC protein
M1C60_00465	COG0542	response to heat
M1C60_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M1C60_00480	COG4956	integral membrane protein (PIN domain superfamily)
M1C60_00500	COG1045	serine acetyltransferase
M1C60_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1C60_00520	COG3688	RNA-binding protein containing a PIN domain
M1C60_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1C60_00540	COG0250	Participates in transcription elongation, termination and antitermination
M1C60_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M1C60_00565	COG2813	Specifically methylates the guanine in position
M1C60_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M1C60_00580	COG1358	cellular component organization or biogenesis
M1C60_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
M1C60_00710	COG0201	protein transport
M1C60_00720	COG0024	Methionine aminopeptidase
M1C60_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M1C60_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1C60_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_00795	COG0489	protein tyrosine kinase activity
M1C60_00805	COG2194	sulfuric ester hydrolase activity
M1C60_00810	COG0726	polysaccharide deacetylase
M1C60_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M1C60_00895	COG4856	YbbR-like protein
M1C60_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1C60_00915	COG0596	Alpha beta hydrolase
M1C60_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M1C60_00940	COG1506	peptidase
M1C60_00940	COG4946	Tricorn protease homolog
M1C60_00940	COG0823	Involved in the tonB-independent uptake of proteins
M1C60_00975	COG2011	ABC-type metal ion transport system permease component
M1C60_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_00985	COG1464	Belongs to the NlpA lipoprotein family
M1C60_00990	COG0604	alcohol dehydrogenase
M1C60_01000	COG0277	FAD linked oxidase domain protein
M1C60_01005	COG2271	Major facilitator Superfamily
M1C60_01015	COG2814	Major facilitator Superfamily
M1C60_01030	COG0601	transmembrane transport
M1C60_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_01040	COG0444	Belongs to the ABC transporter superfamily
M1C60_01045	COG4608	Belongs to the ABC transporter superfamily
M1C60_01050	COG4166	transmembrane transport
M1C60_01060	COG2207	Transcriptional regulator
M1C60_01075	COG4166	transmembrane transport
M1C60_01080	COG4166	transmembrane transport
M1C60_01085	COG0656	L-ascorbic acid biosynthetic process
M1C60_01105	COG4149	molybdate abc transporter
M1C60_01115	COG1910	domain protein
M1C60_01125	COG0583	DNA-binding transcription factor activity
M1C60_01130	COG0697	spore germination
M1C60_01145	COG0204	Acyl-transferase
M1C60_01155	COG1609	Transcriptional regulator
M1C60_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_01175	COG0084	hydrolase, TatD family'
M1C60_01180	COG5298	Protein conserved in bacteria
M1C60_01205	COG0488	(ABC) transporter
M1C60_01220	COG0747	negative chemotaxis
M1C60_01225	COG0601	transmembrane transport
M1C60_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_01235	COG0444	Belongs to the ABC transporter superfamily
M1C60_01240	COG4608	Belongs to the ABC transporter superfamily
M1C60_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
M1C60_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1C60_01290	COG2814	Major facilitator Superfamily
M1C60_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1C60_01310	COG4294	response to UV
M1C60_01315	COG0705	Rhomboid family
M1C60_01315	COG0457	Tetratricopeptide repeat
M1C60_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1C60_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1C60_01335	COG0864	Transcriptional regulator
M1C60_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
M1C60_01345	COG2183	response to ionizing radiation
M1C60_01440	COG0802	atpase or kinase
M1C60_01445	COG1214	PFAM Peptidase M22, glycoprotease
M1C60_01450	COG0456	acetyltransferase
M1C60_01460	COG0488	(ABC) transporter
M1C60_01475	COG1266	CAAX protease self-immunity
M1C60_01495	COG2252	PERMEase
M1C60_01535	COG2226	methyltransferase
M1C60_01580	COG1968	undecaprenyl-diphosphatase activity
M1C60_01595	COG2205	protein histidine kinase activity
M1C60_01600	COG0745	RESPONSE REGULATOR receiver
M1C60_01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M1C60_01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1C60_01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1C60_01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1C60_01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M1C60_01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1C60_01680	COG0151	Belongs to the GarS family
M1C60_01705	COG0210	DNA helicase
M1C60_01715	COG4851	CamS sex pheromone cAM373 precursor
M1C60_01735	COG1335	isochorismatase
M1C60_01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_01745	COG2011	ABC-type metal ion transport system permease component
M1C60_01750	COG1464	Belongs to the NlpA lipoprotein family
M1C60_01775	COG1846	Transcriptional regulator
M1C60_01800	COG1597	lipid kinase activity
M1C60_01805	COG0546	phosphoglycolate phosphatase activity
M1C60_01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1C60_01820	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_01825	COG2076	Multidrug Resistance protein
M1C60_01830	COG2309	aminopeptidase activity
M1C60_01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1C60_01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1C60_01865	COG4807	Protein conserved in bacteria
M1C60_01890	COG1757	Na H antiporter
M1C60_01895	COG1473	amidohydrolase
M1C60_01910	COG0450	alkyl hydroperoxide reductase
M1C60_01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_01955	COG0166	Belongs to the GPI family
M1C60_01990	COG5002	protein histidine kinase activity
M1C60_02010	COG3541	Predicted nucleotidyltransferase
M1C60_02015	COG2814	Major facilitator Superfamily
M1C60_02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_02020	COG0723	plastoquinol--plastocyanin reductase activity
M1C60_02030	COG0765	amino acid transport
M1C60_02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_02045	COG0840	transmembrane signaling receptor activity
M1C60_02050	COG0840	transmembrane signaling receptor activity
M1C60_02055	COG0366	Alpha amylase catalytic
M1C60_02060	COG1263	PTS System
M1C60_02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_02060	COG2190	(PTS) system
M1C60_02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M1C60_02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_02115	COG1116	anion transmembrane transporter activity
M1C60_02120	COG0488	(ABC) transporter
M1C60_02165	COG2270	Major facilitator Superfamily
M1C60_02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_02195	COG2310	stress, protein
M1C60_02200	COG2310	stress, protein
M1C60_02205	COG2310	stress, protein
M1C60_02210	COG0861	Integral membrane protein TerC family
M1C60_02220	COG3853	Toxic anion resistance protein (TelA)
M1C60_02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1C60_02245	COG1295	ribonuclease BN
M1C60_02250	COG2217	Heavy metal translocating P-type atpase
M1C60_02255	COG0697	spore germination
M1C60_02275	COG0586	Pfam SNARE associated Golgi protein
M1C60_02290	COG3871	stress protein (general stress protein 26)
M1C60_02295	COG0387	Pfam Sodium calcium exchanger
M1C60_02305	COG0535	radical SAM domain protein
M1C60_02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1C60_02335	COG0582	viral genome integration into host DNA
M1C60_02345	COG1396	sequence-specific DNA binding
M1C60_02360	COG1396	sequence-specific DNA binding
M1C60_02395	COG1484	DNA-dependent DNA replication
M1C60_02625	COG0101	tRNA pseudouridine synthase activity
M1C60_02635	COG3829	transcription factor binding
M1C60_02645	COG0833	amino acid
M1C60_02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1C60_02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_02680	COG1263	PTS System
M1C60_02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_02700	COG0463	Glycosyl transferase, family 2
M1C60_02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1C60_02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M1C60_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M1C60_02745	COG1228	amidohydrolase
M1C60_02750	COG1090	epimerase
M1C60_02780	COG1988	membrane-bound metal-dependent
M1C60_02785	COG1194	a g-specific adenine glycosylase
M1C60_02810	COG1132	(ABC) transporter
M1C60_02815	COG4129	membrane
M1C60_02820	COG0069	glutamate synthase activity
M1C60_02820	COG0070	glutamate synthase
M1C60_02820	COG0067	glutamate synthase
M1C60_02830	COG4555	ABC transporter
M1C60_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1C60_02855	COG0735	belongs to the Fur family
M1C60_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M1C60_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1C60_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1C60_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1C60_03005	COG2766	serine protein kinase
M1C60_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1C60_03040	COG2268	Band 7 protein
M1C60_03050	COG3290	protein histidine kinase activity
M1C60_03055	COG4565	transcriptional regulatory protein
M1C60_03060	COG2851	Citrate transporter
M1C60_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1C60_03085	COG3842	ATPase activity
M1C60_03090	COG1175	transmembrane transport
M1C60_03095	COG0395	ABC-type sugar transport system, permease component
M1C60_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1C60_03110	COG0745	RESPONSE REGULATOR receiver
M1C60_03115	COG5002	protein histidine kinase activity
M1C60_03125	COG4990	cell redox homeostasis
M1C60_03135	COG3290	protein histidine kinase activity
M1C60_03140	COG4565	transcriptional regulatory protein
M1C60_03145	COG3493	citrate carrier protein
M1C60_03150	COG0281	malic enzyme
M1C60_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_03175	COG5002	protein histidine kinase activity
M1C60_03180	COG0745	RESPONSE REGULATOR receiver
M1C60_03185	COG0456	acetyltransferase
M1C60_03185	COG0454	-acetyltransferase
M1C60_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1C60_03195	COG3383	formate dehydrogenase (NAD+) activity
M1C60_03215	COG0531	amino acid
M1C60_03220	COG0640	Transcriptional regulator
M1C60_03225	COG2217	Heavy metal translocating P-type atpase
M1C60_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M1C60_03245	COG3227	Zinc metalloprotease (Elastase)
M1C60_03265	COG2720	vancomycin resistance protein
M1C60_03270	COG1316	TRANSCRIPTIONal
M1C60_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_03280	COG0346	lactoylglutathione lyase activity
M1C60_03290	COG1027	Aspartate ammonia-lyase
M1C60_03295	COG1620	l-lactate permease
M1C60_03310	COG3104	oligopeptide transport
M1C60_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_03335	COG2226	methyltransferase
M1C60_03340	COG0156	8-amino-7-oxononanoate synthase activity
M1C60_03360	COG0714	Associated with various cellular activities
M1C60_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_03385	COG0531	amino acid
M1C60_03390	COG2188	Transcriptional regulator
M1C60_03395	COG1263	PTS System
M1C60_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_03400	COG0366	Alpha amylase catalytic
M1C60_03415	COG0697	spore germination
M1C60_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_03430	COG1115	amino acid carrier protein
M1C60_03435	COG1126	abc transporter atp-binding protein
M1C60_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_03445	COG0765	amino acid transport
M1C60_03450	COG0765	amino acid transport
M1C60_03455	COG0833	amino acid
M1C60_03480	COG2378	regulation of single-species biofilm formation
M1C60_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1C60_03490	COG5002	protein histidine kinase activity
M1C60_03505	COG0659	secondary active sulfate transmembrane transporter activity
M1C60_03520	COG0747	negative chemotaxis
M1C60_03530	COG0601	transmembrane transport
M1C60_03535	COG4608	Belongs to the ABC transporter superfamily
M1C60_03545	COG2271	Major facilitator Superfamily
M1C60_03550	COG1846	Transcriptional regulator
M1C60_03560	COG1609	Transcriptional regulator
M1C60_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1C60_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1C60_03585	COG1879	ABC-type sugar transport system periplasmic component
M1C60_03610	COG1063	alcohol dehydrogenase
M1C60_03625	COG3568	Endonuclease Exonuclease Phosphatase
M1C60_03650	COG1968	undecaprenyl-diphosphatase activity
M1C60_03655	COG0840	transmembrane signaling receptor activity
M1C60_03665	COG1476	TRANSCRIPTIONal
M1C60_03680	COG3104	oligopeptide transport
M1C60_03685	COG1114	Component of the transport system for branched-chain amino acids
M1C60_03700	COG1113	amino acid transport
M1C60_03705	COG2252	PERMEase
M1C60_03730	COG0569	domain protein
M1C60_03730	COG0475	glutathione-regulated potassium exporter activity
M1C60_03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1C60_03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1C60_03755	COG4990	cell redox homeostasis
M1C60_03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_03775	COG0697	spore germination
M1C60_03780	COG0531	amino acid
M1C60_03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_03800	COG1918	ferrous iron import across plasma membrane
M1C60_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1C60_03810	COG0573	inorganic phosphate transmembrane transporter activity
M1C60_03815	COG0581	inorganic phosphate transmembrane transporter activity
M1C60_03945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M1C60_03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1C60_03970	COG1116	anion transmembrane transporter activity
M1C60_03975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_03980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_03985	COG0352	thiamine-phosphate diphosphorylase activity
M1C60_03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_03995	COG2104	thiamine diphosphate biosynthetic process
M1C60_04005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_04010	COG0351	phosphomethylpyrimidine kinase
M1C60_04050	COG2205	protein histidine kinase activity
M1C60_04055	COG2814	Major facilitator Superfamily
M1C60_04060	COG1846	Transcriptional regulator
M1C60_04075	COG2252	PERMEase
M1C60_04080	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1C60_04100	COG1621	beta-fructofuranosidase activity
M1C60_04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_04105	COG1263	PTS System
M1C60_04110	COG1609	Transcriptional regulator
M1C60_04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M1C60_04160	COG0778	Nitroreductase
M1C60_04165	COG2719	SpoVR family
M1C60_04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1C60_04195	COG1937	Protein conserved in bacteria
M1C60_04200	COG0425	Belongs to the sulfur carrier protein TusA family
M1C60_04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_04210	COG0425	Belongs to the sulfur carrier protein TusA family
M1C60_04225	COG2210	Belongs to the sulfur carrier protein TusA family
M1C60_04230	COG0730	response to heat
M1C60_04240	COG1316	TRANSCRIPTIONal
M1C60_04245	COG0604	alcohol dehydrogenase
M1C60_04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
M1C60_04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_04265	COG3711	transcriptional antiterminator
M1C60_04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_04295	COG1388	LysM domain
M1C60_04295	COG3584	3D domain protein
M1C60_04300	COG0577	efflux transmembrane transporter activity
M1C60_04305	COG1136	(ABC) transporter
M1C60_04315	COG5522	Integral membrane protein (intg_mem_TP0381)
M1C60_04330	COG1114	Component of the transport system for branched-chain amino acids
M1C60_04335	COG3546	catalase activity
M1C60_04370	COG0586	Pfam SNARE associated Golgi protein
M1C60_04405	COG0531	amino acid
M1C60_04410	COG0475	glutathione-regulated potassium exporter activity
M1C60_04420	COG1737	Transcriptional regulator
M1C60_04430	COG1263	PTS System
M1C60_04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_04440	COG2259	Doxx family
M1C60_04455	COG0697	spore germination
M1C60_04460	COG1522	sequence-specific DNA binding
M1C60_04475	COG2076	Multidrug Resistance protein
M1C60_04480	COG1309	transcriptional regulator
M1C60_04485	COG2814	Major facilitator Superfamily
M1C60_04490	COG1733	regulation of RNA biosynthetic process
M1C60_04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_04505	COG4533	DNA binding
M1C60_04510	COG2211	Major facilitator Superfamily
M1C60_04520	COG0693	protein deglycase activity
M1C60_04525	COG0693	protein deglycase activity
M1C60_04525	COG0753	catalase activity
M1C60_04535	COG0531	amino acid
M1C60_04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1C60_04550	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_04555	COG1132	(ABC) transporter
M1C60_04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_04570	COG0765	amino acid transport
M1C60_04575	COG1126	abc transporter atp-binding protein
M1C60_04590	COG0189	ligase activity
M1C60_04620	COG0028	Belongs to the TPP enzyme family
M1C60_04625	COG3527	Alpha-acetolactate decarboxylase
M1C60_04640	COG0561	phosphatase activity
M1C60_04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1C60_04670	COG0659	secondary active sulfate transmembrane transporter activity
M1C60_04690	COG0653	protein targeting
M1C60_04695	COG2244	polysaccharide biosynthetic process
M1C60_04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_04710	COG4196	transglutaminase domain protein
M1C60_04725	COG1696	Membrane protein involved in D-alanine export
M1C60_04740	COG1024	Enoyl-CoA hydratase
M1C60_04760	COG1363	Peptidase, m42
M1C60_04780	COG3938	Belongs to the proline racemase family
M1C60_04820	COG0601	transmembrane transport
M1C60_04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_04835	COG4608	Belongs to the ABC transporter superfamily
M1C60_04870	COG0477	Major facilitator Superfamily
M1C60_04875	COG3290	protein histidine kinase activity
M1C60_04880	COG4565	transcriptional regulatory protein
M1C60_04885	COG3181	Tripartite tricarboxylate transporter family receptor
M1C60_04915	COG0789	Transcriptional regulator
M1C60_04915	COG4978	Transcriptional regulator
M1C60_04930	COG0305	Participates in initiation and elongation during chromosome replication
M1C60_04970	COG0477	Major facilitator Superfamily
M1C60_05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_05015	COG3320	Male sterility
M1C60_05020	COG1309	transcriptional regulator
M1C60_05040	COG1183	phosphatidylcholine synthase activity
M1C60_05060	COG2376	Dihydroxyacetone kinase
M1C60_05070	COG2376	Dihydroxyacetone kinase
M1C60_05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_05080	COG1959	2 iron, 2 sulfur cluster binding
M1C60_05110	COG3437	response regulator, receiver
M1C60_05110	COG2770	Histidine kinase
M1C60_05160	COG3237	CsbD-like
M1C60_05185	COG1191	sigma factor activity
M1C60_05195	COG2208	phosphoserine phosphatase activity
M1C60_05200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1C60_05205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_05205	COG2198	Histidine kinase
M1C60_05205	COG2205	protein histidine kinase activity
M1C60_05205	COG0784	Response regulator, receiver
M1C60_05260	COG0420	3'-5' exonuclease activity
M1C60_05285	COG1309	transcriptional regulator
M1C60_05290	COG2814	Major facilitator Superfamily
M1C60_05295	COG0346	lactoylglutathione lyase activity
M1C60_05305	COG0457	Tetratricopeptide repeat
M1C60_05310	COG2267	carboxylic ester hydrolase activity
M1C60_05330	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1C60_05335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M1C60_05345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M1C60_05385	COG0477	Major facilitator Superfamily
M1C60_05390	COG0477	Major facilitator Superfamily
M1C60_05400	COG3973	AAA domain
M1C60_05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_05425	COG4980	gas vesicle protein
M1C60_05430	COG0537	adenosine 5'-monophosphoramidase activity
M1C60_05435	COG1131	(ABC) transporter
M1C60_05440	COG4473	ABC transporter
M1C60_05455	COG1309	transcriptional regulator
M1C60_05465	COG3402	PFAM membrane-flanked domain
M1C60_05510	COG3402	PFAM membrane-flanked domain
M1C60_05515	COG3428	Bacterial PH domain
M1C60_05520	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_05530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M1C60_05535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1C60_05540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1C60_05575	COG1309	transcriptional regulator
M1C60_05580	COG1511	domain protein
M1C60_05605	COG1609	Transcriptional regulator
M1C60_05615	COG1234	tRNA 3'-trailer cleavage
M1C60_05620	COG0095	Lipoate-protein ligase
M1C60_05630	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_05660	COG3209	COG3209 Rhs family protein
M1C60_05700	COG1078	dGTPase activity
M1C60_05710	COG1595	DNA-templated transcription, initiation
M1C60_05715	COG2207	Transcriptional regulator
M1C60_05715	COG3708	Transcriptional regulator
M1C60_05730	COG2205	protein histidine kinase activity
M1C60_05735	COG0745	RESPONSE REGULATOR receiver
M1C60_05760	COG0501	Belongs to the peptidase M48B family
M1C60_05765	COG0840	transmembrane signaling receptor activity
M1C60_05770	COG0697	spore germination
M1C60_05790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1C60_05795	COG2224	Isocitrate lyase
M1C60_05820	COG4903	ComK protein
M1C60_05825	COG0398	Pfam SNARE associated Golgi protein
M1C60_05835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M1C60_05840	COG1074	ATP-dependent DNA helicase activity
M1C60_05885	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1C60_05910	COG0367	asparagine synthase
M1C60_05915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1C60_05920	COG0753	catalase activity
M1C60_05925	COG0004	ammonium transporteR
M1C60_05945	COG2996	Protein conserved in bacteria
M1C60_05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_05980	COG0561	phosphatase activity
M1C60_05990	COG0542	response to heat
M1C60_06000	COG2267	carboxylic ester hydrolase activity
M1C60_06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1C60_06025	COG5504	Zn-dependent protease
M1C60_06035	COG0180	Tryptophanyl-tRNA synthetase
M1C60_06045	COG4166	transmembrane transport
M1C60_06050	COG0601	transmembrane transport
M1C60_06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_06060	COG0444	Belongs to the ABC transporter superfamily
M1C60_06065	COG4608	Belongs to the ABC transporter superfamily
M1C60_06070	COG0534	Mate efflux family protein
M1C60_06075	COG4166	transmembrane transport
M1C60_06090	COG0861	Integral membrane protein TerC family
M1C60_06095	COG4862	establishment of competence for transformation
M1C60_06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_06110	COG1164	Oligoendopeptidase f
M1C60_06120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1C60_06125	COG2346	COG2346, Truncated hemoglobins
M1C60_06130	COG4116	CYTH
M1C60_06140	COG2357	RelA SpoT domain protein
M1C60_06150	COG0564	pseudouridine synthase activity
M1C60_06170	COG0463	Glycosyl transferase, family 2
M1C60_06170	COG1216	Glycosyl transferase, family 2
M1C60_06190	COG0463	Glycosyl transferase, family 2
M1C60_06190	COG0457	Tetratricopeptide repeat
M1C60_06210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M1C60_06225	COG1091	dTDP-4-dehydrorhamnose reductase activity
M1C60_06270	COG2153	protein acetylation
M1C60_06280	COG2382	esterase
M1C60_06295	COG5492	domain, Protein
M1C60_06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_06310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1C60_06310	COG0512	Glutamine amidotransferase of anthranilate synthase
M1C60_06345	COG1620	l-lactate permease
M1C60_06350	COG5634	Uncharacterized conserved protein (DUF2278)
M1C60_06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_06415	COG1476	TRANSCRIPTIONal
M1C60_06475	COG2226	methyltransferase
M1C60_06485	COG1686	Belongs to the peptidase S11 family
M1C60_06490	COG0681	Belongs to the peptidase S26 family
M1C60_06525	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_06530	COG3842	ATPase activity
M1C60_06535	COG1176	ABC-type spermidine putrescine transport system, permease component I
M1C60_06540	COG1177	transmembrane transport
M1C60_06545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M1C60_06555	COG2409	Drug exporters of the RND superfamily
M1C60_06565	COG0564	pseudouridine synthase activity
M1C60_06575	COG2340	Cysteine-rich secretory protein family
M1C60_06580	COG0247	lactate metabolic process
M1C60_06585	COG0277	FAD linked oxidase domain protein
M1C60_06590	COG3835	regulator
M1C60_06600	COG0745	RESPONSE REGULATOR receiver
M1C60_06605	COG5002	protein histidine kinase activity
M1C60_06610	COG2186	Transcriptional regulator
M1C60_06630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1C60_06640	COG2116	formate transmembrane transporter activity
M1C60_06645	COG0861	Integral membrane protein TerC family
M1C60_06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_06660	COG2030	dehydratase
M1C60_06680	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_06685	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1C60_06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_06710	COG1840	ABC-type Fe3 transport system, periplasmic component
M1C60_06740	COG1349	DNA-binding transcription factor activity
M1C60_06760	COG2861	carbohydrate metabolic process
M1C60_06770	COG3852	Histidine kinase
M1C60_06775	COG1846	Transcriptional regulator
M1C60_06785	COG2318	DinB family
M1C60_06795	COG5002	protein histidine kinase activity
M1C60_06805	COG0720	synthase
M1C60_06820	COG4873	Protein conserved in bacteria
M1C60_06850	COG1780	Probably involved in ribonucleotide reductase function
M1C60_06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1C60_06875	COG1725	Transcriptional regulator
M1C60_06880	COG1131	(ABC) transporter
M1C60_06890	COG1131	(ABC) transporter
M1C60_06895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_06910	COG1522	sequence-specific DNA binding
M1C60_06920	COG1335	isochorismatase
M1C60_06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_06935	COG2070	2-Nitropropane dioxygenase
M1C60_06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1C60_06950	COG1696	Membrane protein involved in D-alanine export
M1C60_06975	COG0716	FMN binding
M1C60_06990	COG3173	Aminoglycoside phosphotransferase
M1C60_07010	COG0534	Mate efflux family protein
M1C60_07015	COG1968	undecaprenyl-diphosphatase activity
M1C60_07030	COG1846	Transcriptional regulator
M1C60_07040	COG1301	dicarboxylic acid transport
M1C60_07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_07050	COG4709	membrane
M1C60_07055	COG3874	Sporulation protein YtfJ
M1C60_07075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_07080	COG0028	Belongs to the TPP enzyme family
M1C60_07085	COG0440	acetolactate synthase activity
M1C60_07090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1C60_07100	COG0473	3-isopropylmalate dehydrogenase activity
M1C60_07125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1C60_07160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1C60_07175	COG1183	phosphatidylcholine synthase activity
M1C60_07180	COG1368	sulfuric ester hydrolase activity
M1C60_07190	COG0019	diaminopimelate decarboxylase activity
M1C60_07210	COG0529	Catalyzes the synthesis of activated sulfate
M1C60_07215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1C60_07235	COG1648	precorrin-2 dehydrogenase activity
M1C60_07240	COG0733	neurotransmitter:sodium symporter activity
M1C60_07260	COG1757	Na H antiporter
M1C60_07275	COG4758	membrane
M1C60_07280	COG4585	Histidine kinase
M1C60_07285	COG2197	response regulator
M1C60_07295	COG1114	Component of the transport system for branched-chain amino acids
M1C60_07330	COG1017	nitric oxide dioxygenase activity
M1C60_07330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1C60_07345	COG0730	response to heat
M1C60_07350	COG0306	phosphate transporter
M1C60_07355	COG1392	Phosphate transport regulator
M1C60_07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_07375	COG3852	Histidine kinase
M1C60_07380	COG1801	Protein of unknown function DUF72
M1C60_07390	COG0582	viral genome integration into host DNA
M1C60_07395	COG5002	protein histidine kinase activity
M1C60_07415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M1C60_07415	COG0392	lysyltransferase activity
M1C60_07430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_07435	COG1686	Belongs to the peptidase S11 family
M1C60_07440	COG2715	membrane protein required for spore maturation
M1C60_07445	COG0700	Nucleoside recognition
M1C60_07450	COG1187	pseudouridine synthase activity
M1C60_07460	COG1333	cytochrome c biogenesis protein
M1C60_07465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1C60_07470	COG0745	RESPONSE REGULATOR receiver
M1C60_07475	COG5002	protein histidine kinase activity
M1C60_07480	COG2096	Adenosyltransferase
M1C60_07495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M1C60_07500	COG1141	Ferredoxin
M1C60_07505	COG4955	Helix-turn-helix domain
M1C60_07510	COG0514	ATP-dependent DNA helicase (RecQ)
M1C60_07515	COG1266	CAAX protease self-immunity
M1C60_07535	COG4862	establishment of competence for transformation
M1C60_07540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1C60_07560	COG0492	ferredoxin-NADP+ reductase activity
M1C60_07565	COG0252	asparaginase activity
M1C60_07635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_07650	COG0142	geranyltranstransferase activity
M1C60_07660	COG0142	geranyltranstransferase activity
M1C60_07680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1C60_07685	COG0457	Tetratricopeptide repeat
M1C60_07705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M1C60_07715	COG4347	Protein of unknown function (DUF1405)
M1C60_07730	COG2738	Putative neutral zinc metallopeptidase
M1C60_07740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_07745	COG1694	Mazg nucleotide pyrophosphohydrolase
M1C60_07760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_07765	COG0438	transferase activity, transferring glycosyl groups
M1C60_07800	COG1199	ATP-dependent helicase activity
M1C60_07800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1C60_07820	COG3935	DnaD domain protein
M1C60_07825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1C60_07835	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1C60_07835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_07895	COG0116	Belongs to the methyltransferase superfamily
M1C60_07905	COG1199	ATP-dependent helicase activity
M1C60_07910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M1C60_07920	COG3173	Aminoglycoside phosphotransferase
M1C60_07925	COG0024	Methionine aminopeptidase
M1C60_07935	COG2233	PERMEase
M1C60_07940	COG2311	Membrane
M1C60_07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_07955	COG0456	acetyltransferase
M1C60_08005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_08030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1C60_08045	COG1215	transferase activity, transferring glycosyl groups
M1C60_08050	COG0438	transferase activity, transferring glycosyl groups
M1C60_08065	COG0454	-acetyltransferase
M1C60_08085	COG0328	RNA-DNA hybrid ribonuclease activity
M1C60_08125	COG1280	lysine exporter protein (LysE YggA)
M1C60_08140	COG3162	membrane
M1C60_08145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_08160	COG0475	glutathione-regulated potassium exporter activity
M1C60_08165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_08170	COG4978	Transcriptional regulator
M1C60_08170	COG0789	Transcriptional regulator
M1C60_08180	COG2323	membrane
M1C60_08185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
M1C60_08240	COG1923	regulation of RNA biosynthetic process
M1C60_08250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1C60_08255	COG1360	Flagellar Motor Protein
M1C60_08260	COG2201	protein-glutamate methylesterase activity
M1C60_08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_08270	COG1776	CheC inhibitor of MCP methylation
M1C60_08285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1C60_08305	COG1256	bacterial-type flagellum assembly
M1C60_08330	COG1815	bacterial-type flagellum-dependent cell motility
M1C60_08335	COG1558	bacterial-type flagellum-dependent cell motility
M1C60_08350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_08360	COG1157	protein secretion by the type III secretion system
M1C60_08395	COG0835	chemotaxis
M1C60_08395	COG0784	Response regulator, receiver
M1C60_08405	COG0463	Glycosyl transferase, family 2
M1C60_08430	COG0457	Tetratricopeptide repeat
M1C60_08430	COG0463	Glycosyl transferase, family 2
M1C60_08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M1C60_08450	COG0741	lytic transglycosylase activity
M1C60_08465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_08465	COG1776	CheC inhibitor of MCP methylation
M1C60_08475	COG1338	Plays a role in the flagellum-specific transport system
M1C60_08480	COG1987	bacterial-type flagellum assembly
M1C60_08490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1C60_08495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1C60_08500	COG1419	protein localization to endoplasmic reticulum
M1C60_08505	COG4786	Flagellar basal body rod
M1C60_08510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_08535	COG1309	transcriptional regulator
M1C60_08555	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_08580	COG0583	DNA-binding transcription factor activity
M1C60_08590	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1C60_08600	COG1234	tRNA 3'-trailer cleavage
M1C60_08625	COG1686	Belongs to the peptidase S11 family
M1C60_08635	COG0406	alpha-ribazole phosphatase activity
M1C60_08665	COG0367	asparagine synthase
M1C60_08695	COG1802	Transcriptional regulator
M1C60_08700	COG0697	spore germination
M1C60_08705	COG0523	cobalamin synthesis protein
M1C60_08710	COG0701	Predicted permease
M1C60_08720	COG0438	transferase activity, transferring glycosyl groups
M1C60_08720	COG1216	Glycosyl transferase, family 2
M1C60_08725	COG1757	Na H antiporter
M1C60_08730	COG0114	fumarate hydratase activity
M1C60_08755	COG3340	Belongs to the peptidase S51 family
M1C60_08775	COG0785	Cytochrome C biogenesis protein
M1C60_08805	COG2733	membrane
M1C60_08840	COG1131	(ABC) transporter
M1C60_08855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_08860	COG0528	UMP kinase activity
M1C60_08870	COG1027	Aspartate ammonia-lyase
M1C60_08875	COG0281	malic enzyme
M1C60_08880	COG4191	Histidine kinase
M1C60_08885	COG0784	Response regulator, receiver
M1C60_08890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1C60_08950	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_08960	COG2814	Major facilitator Superfamily
M1C60_08975	COG1966	Carbon starvation protein
M1C60_08990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1C60_09010	COG2223	nitrite transmembrane transporter activity
M1C60_09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_09030	COG2244	polysaccharide biosynthetic process
M1C60_09035	COG0733	neurotransmitter:sodium symporter activity
M1C60_09045	COG5566	PFAM Mor transcription activator
M1C60_09050	COG2323	membrane
M1C60_09070	COG2084	Dehydrogenase
M1C60_09085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_09095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_09100	COG0028	Belongs to the TPP enzyme family
M1C60_09105	COG0440	acetolactate synthase activity
M1C60_09110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1C60_09120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1C60_09145	COG2814	Major facilitator Superfamily
M1C60_09150	COG3384	dioxygenase
M1C60_09160	COG3279	Response regulator of the LytR AlgR family
M1C60_09165	COG0427	acetyl-CoA hydrolase
M1C60_09185	COG1073	alpha beta
M1C60_09215	COG0535	radical SAM domain protein
M1C60_09220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_09240	COG1914	H( )-stimulated, divalent metal cation uptake system
M1C60_09255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1C60_09285	COG2390	Transcriptional regulator
M1C60_09295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_09300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M1C60_09315	COG4224	UPF0291 protein
M1C60_09335	COG0006	proline dipeptidase activity
M1C60_09340	COG2132	Multicopper oxidase
M1C60_09355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1C60_09370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_09385	COG1276	copper resistance
M1C60_09385	COG2372	response to copper ion
M1C60_09390	COG4549	nuclear export factor GLE1
M1C60_09400	COG0697	spore germination
M1C60_09405	COG0583	DNA-binding transcription factor activity
M1C60_09410	COG1959	2 iron, 2 sulfur cluster binding
M1C60_09415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1C60_09430	COG0628	permease
M1C60_09440	COG1231	oxidoreductase activity
M1C60_09445	COG0523	cobalamin synthesis protein
M1C60_09460	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_09465	COG2030	dehydratase
M1C60_09470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_09480	COG0411	ABC transporter
M1C60_09500	COG0583	DNA-binding transcription factor activity
M1C60_09510	COG1942	4-Oxalocrotonate Tautomerase
M1C60_09520	COG1846	Transcriptional regulator
M1C60_09530	COG1271	oxidase subunit
M1C60_09535	COG1294	oxidase, subunit
M1C60_09540	COG4988	ABC transporter
M1C60_09545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M1C60_09565	COG1686	Belongs to the peptidase S11 family
M1C60_09580	COG0791	NLP P60 protein
M1C60_09580	COG1388	LysM domain
M1C60_09595	COG0745	RESPONSE REGULATOR receiver
M1C60_09600	COG5002	protein histidine kinase activity
M1C60_09610	COG0300	oxidoreductase activity
M1C60_09645	COG0460	homoserine dehydrogenase
M1C60_09670	COG1316	TRANSCRIPTIONal
M1C60_09680	COG0745	RESPONSE REGULATOR receiver
M1C60_09685	COG5002	protein histidine kinase activity
M1C60_09700	COG1285	pathogenesis
M1C60_09705	COG1247	-acetyltransferase
M1C60_09725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_09735	COG1082	Xylose isomerase domain protein TIM barrel
M1C60_09750	COG1279	arginine transmembrane transporter activity
M1C60_09760	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1C60_09800	COG2002	toxin-antitoxin pair type II binding
M1C60_09805	COG1404	Belongs to the peptidase S8 family
M1C60_09810	COG0640	Transcriptional regulator
M1C60_09815	COG0667	Aldo Keto reductase
M1C60_09820	COG2814	Major facilitator Superfamily
M1C60_09845	COG0840	transmembrane signaling receptor activity
M1C60_09860	COG3949	Membrane
M1C60_09865	COG0783	Belongs to the Dps family
M1C60_09880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_09890	COG1231	oxidoreductase activity
M1C60_09900	COG4989	oxidoreductase activity
M1C60_09905	COG0523	cobalamin synthesis protein
M1C60_09910	COG0456	acetyltransferase
M1C60_09970	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1C60_09970	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1C60_09980	COG0702	epimerase
M1C60_09990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1C60_10000	COG4166	transmembrane transport
M1C60_10015	COG0406	alpha-ribazole phosphatase activity
M1C60_10025	COG5337	Spore coat protein CotH
M1C60_10030	COG1051	belongs to the nudix hydrolase family
M1C60_10035	COG0586	Pfam SNARE associated Golgi protein
M1C60_10040	COG2244	polysaccharide biosynthetic process
M1C60_10050	COG0701	Predicted permease
M1C60_10055	COG3689	TIGRFAM TIGR03943 family protein
M1C60_10060	COG1607	acyl-coa hydrolase
M1C60_10070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_10085	COG0702	epimerase
M1C60_10090	COG2839	Protein conserved in bacteria
M1C60_10095	COG1253	flavin adenine dinucleotide binding
M1C60_10110	COG1114	Component of the transport system for branched-chain amino acids
M1C60_10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_10135	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_10145	COG1876	peptidase activity
M1C60_10155	COG0154	amidase activity
M1C60_10160	COG2211	Major facilitator Superfamily
M1C60_10180	COG0561	phosphatase activity
M1C60_10190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1C60_10195	COG4106	trans-aconitate 2-methyltransferase activity
M1C60_10210	COG1819	glycosyl
M1C60_10215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_10220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_10255	COG0456	acetyltransferase
M1C60_10310	COG3874	Sporulation protein YtfJ
M1C60_10335	COG2226	methyltransferase
M1C60_10360	COG0346	lactoylglutathione lyase activity
M1C60_10370	COG0604	alcohol dehydrogenase
M1C60_10375	COG1595	DNA-templated transcription, initiation
M1C60_10400	COG0386	Belongs to the glutathione peroxidase family
M1C60_10405	COG1305	Transglutaminase-like
M1C60_10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M1C60_10415	COG0714	Associated with various cellular activities
M1C60_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M1C60_10435	COG1140	nitrate reductase beta subunit
M1C60_10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M1C60_10445	COG2181	nitrate reductase activity
M1C60_10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1C60_10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1C60_10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_10480	COG0303	'Molybdopterin
M1C60_10485	COG0314	molybdopterin synthase activity
M1C60_10495	COG2223	nitrite transmembrane transporter activity
M1C60_10510	COG1648	precorrin-2 dehydrogenase activity
M1C60_10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1C60_10520	COG1587	Uroporphyrinogen-III synthase
M1C60_10525	COG2146	nitrite reductase [NAD(P)H] activity
M1C60_10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1C60_10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
M1C60_10570	COG2359	stage V sporulation protein S
M1C60_10595	COG1418	mRNA catabolic process
M1C60_10600	COG0488	(ABC) transporter
M1C60_10615	COG0629	single-stranded DNA binding
M1C60_10630	COG1413	lyase activity
M1C60_10645	COG2521	methyltransferase
M1C60_10645	COG2136	Putative SAM-dependent methyltransferase
M1C60_10650	COG0018	arginyl-trna synthetase
M1C60_10675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1C60_10695	COG0017	Asparaginyl-tRNA synthetase
M1C60_10715	COG1674	ftsk spoiiie
M1C60_10785	COG1929	Belongs to the glycerate kinase type-1 family
M1C60_10790	COG0471	metal ion transport
M1C60_10795	COG0745	RESPONSE REGULATOR receiver
M1C60_10800	COG3850	Histidine kinase
M1C60_10800	COG5002	protein histidine kinase activity
M1C60_10815	COG0733	neurotransmitter:sodium symporter activity
M1C60_10840	COG2610	gluconate transmembrane transporter activity
M1C60_10845	COG1454	alcohol dehydrogenase
M1C60_10850	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_10860	COG0456	acetyltransferase
M1C60_10875	COG1131	(ABC) transporter
M1C60_10890	COG0546	phosphoglycolate phosphatase activity
M1C60_10910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_10925	COG0768	penicillin binding
M1C60_10930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_10935	COG0204	Acyl-transferase
M1C60_10940	COG1272	protein, Hemolysin III
M1C60_10950	COG0805	protein transport
M1C60_10960	COG1307	EDD domain protein, DegV family
M1C60_10965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M1C60_10970	COG1999	signal sequence binding
M1C60_10975	COG0071	Belongs to the small heat shock protein (HSP20) family
M1C60_10980	COG0367	asparagine synthase
M1C60_10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_11035	COG0668	transmembrane transport
M1C60_11040	COG4585	Histidine kinase
M1C60_11040	COG2203	Gaf domain
M1C60_11045	COG2197	response regulator
M1C60_11055	COG1064	alcohol dehydrogenase
M1C60_11110	COG0517	IMP dehydrogenase activity
M1C60_11110	COG1125	glycine betaine transport
M1C60_11115	COG1174	glycine betaine transport
M1C60_11150	COG1253	flavin adenine dinucleotide binding
M1C60_11155	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_11160	COG5506	Protein of unknown function (DUF1694)
M1C60_11175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_11180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1C60_11185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1C60_11190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1C60_11195	COG0456	acetyltransferase
M1C60_11200	COG3829	transcription factor binding
M1C60_11205	COG1509	lysine 2,3-aminomutase activity
M1C60_11245	COG4326	sporulation control protein
M1C60_11250	COG0671	phosphoesterase, PA-phosphatase related
M1C60_11255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1C60_11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_11290	COG1787	Restriction endonuclease
M1C60_11290	COG1715	Restriction endonuclease
M1C60_11380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_11420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_11420	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1C60_11430	COG2814	Major facilitator Superfamily
M1C60_11435	COG4841	protein insertion into membrane
M1C60_11440	COG0372	Belongs to the citrate synthase family
M1C60_11445	COG2079	MmgE PrpD family protein
M1C60_11450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M1C60_11455	COG1960	acyl-CoA dehydrogenase activity
M1C60_11460	COG2084	Dehydrogenase
M1C60_11470	COG1280	lysine exporter protein (LysE YggA)
M1C60_11475	COG1024	Enoyl-CoA hydratase
M1C60_11490	COG0420	3'-5' exonuclease activity
M1C60_11495	COG0419	ATPase involved in DNA repair
M1C60_11515	COG2223	nitrite transmembrane transporter activity
M1C60_11520	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_11525	COG1169	isochorismate synthase
M1C60_11530	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1C60_11535	COG1535	isochorismatase
M1C60_11535	COG3433	isochorismatase activity
M1C60_11540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1C60_11545	COG3251	PFAM MbtH domain protein
M1C60_11550	COG2814	Major facilitator Superfamily
M1C60_11565	COG0776	regulation of translation
M1C60_11575	COG2318	DinB family
M1C60_11585	COG1115	amino acid carrier protein
M1C60_11600	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_11605	COG1187	pseudouridine synthase activity
M1C60_11610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_11625	COG0596	Alpha beta hydrolase
M1C60_11630	COG2814	Major facilitator Superfamily
M1C60_11650	COG2226	methyltransferase
M1C60_11695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_11730	COG1247	-acetyltransferase
M1C60_11760	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1C60_11770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_11780	COG1278	Cold shock
M1C60_11795	COG0010	Belongs to the arginase family
M1C60_11800	COG0561	phosphatase activity
M1C60_11845	COG0583	DNA-binding transcription factor activity
M1C60_11850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1C60_11865	COG0583	DNA-binding transcription factor activity
M1C60_11870	COG2258	MOSC domain
M1C60_11885	COG1132	(ABC) transporter
M1C60_11910	COG1396	sequence-specific DNA binding
M1C60_11935	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
M1C60_11940	COG1595	DNA-templated transcription, initiation
M1C60_11965	COG1649	PFAM Uncharacterised BCR, COG1649
M1C60_11990	COG2971	BadF BadG BcrA BcrD
M1C60_11995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_12000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1C60_12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_12050	COG1309	transcriptional regulator
M1C60_12065	COG1136	(ABC) transporter
M1C60_12065	COG0577	efflux transmembrane transporter activity
M1C60_12070	COG3615	Tellurite resistance protein tehB
M1C60_12070	COG0500	methyltransferase
M1C60_12080	COG2226	methyltransferase
M1C60_12085	COG3961	Belongs to the TPP enzyme family
M1C60_12090	COG1846	Transcriptional regulator
M1C60_12130	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1C60_12145	COG1595	DNA-templated transcription, initiation
M1C60_12155	COG0768	penicillin binding
M1C60_12165	COG2367	Beta-lactamase
M1C60_12170	COG0671	phosphoesterase, PA-phosphatase related
M1C60_12175	COG1609	Transcriptional regulator
M1C60_12180	COG2814	Major facilitator Superfamily
M1C60_12185	COG0673	inositol 2-dehydrogenase activity
M1C60_12195	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_12210	COG0191	fructose-bisphosphate aldolase activity
M1C60_12215	COG3718	enzyme involved in inositol metabolism
M1C60_12240	COG0457	Tetratricopeptide repeat
M1C60_12245	COG1476	TRANSCRIPTIONal
M1C60_12260	COG1876	peptidase activity
M1C60_12280	COG1309	transcriptional regulator
M1C60_12285	COG0488	(ABC) transporter
M1C60_12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_12315	COG1252	NADH dehydrogenase
M1C60_12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_12335	COG1131	(ABC) transporter
M1C60_12345	COG1309	transcriptional regulator
M1C60_12360	COG1960	acyl-CoA dehydrogenase activity
M1C60_12365	COG0439	Biotin carboxylase
M1C60_12370	COG0511	ligase activity, forming carbon-carbon bonds
M1C60_12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1C60_12380	COG1024	Enoyl-CoA hydratase
M1C60_12385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1C60_12390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_12400	COG1247	-acetyltransferase
M1C60_12405	COG0572	uridine kinase
M1C60_12415	COG2318	DinB family
M1C60_12420	COG1686	Belongs to the peptidase S11 family
M1C60_12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1C60_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_12510	COG2814	Major facilitator Superfamily
M1C60_12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_12565	COG1063	alcohol dehydrogenase
M1C60_12595	COG3773	Cell wall hydrolase
M1C60_12605	COG0745	RESPONSE REGULATOR receiver
M1C60_12620	COG0488	(ABC) transporter
M1C60_12635	COG1136	(ABC) transporter
M1C60_12660	COG0460	homoserine dehydrogenase
M1C60_12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1C60_12740	COG2124	cytochrome p450
M1C60_12775	COG0561	phosphatase activity
M1C60_12785	COG0768	penicillin binding
M1C60_12790	COG1819	glycosyl
M1C60_12795	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_12805	COG1122	ATPase activity
M1C60_12820	COG2205	protein histidine kinase activity
M1C60_12830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_12835	COG0604	alcohol dehydrogenase
M1C60_12840	COG0768	penicillin binding
M1C60_12850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_12885	COG0693	protein deglycase activity
M1C60_12915	COG2814	Major facilitator Superfamily
M1C60_12930	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_12950	COG0697	spore germination
M1C60_12980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_12990	COG2223	nitrite transmembrane transporter activity
M1C60_13005	COG2816	NAD+ diphosphatase activity
M1C60_13010	COG0592	DNA-directed DNA polymerase activity
M1C60_13015	COG1051	belongs to the nudix hydrolase family
M1C60_13050	COG3878	Protein conserved in bacteria
M1C60_13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1C60_13115	COG0322	excinuclease ABC activity
M1C60_13155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_13180	COG1011	Hydrolase
M1C60_13200	COG0076	glutamate decarboxylase activity
M1C60_13215	COG1523	belongs to the glycosyl hydrolase 13 family
M1C60_13220	COG3227	Zinc metalloprotease (Elastase)
M1C60_13250	COG0697	spore germination
M1C60_13255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_13285	COG4129	membrane
M1C60_13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_13305	COG2959	enzyme of heme biosynthesis
M1C60_13325	COG3483	tryptophan 2,3-dioxygenase activity
M1C60_13330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
M1C60_13335	COG3844	kynureninase activity
M1C60_13340	COG1309	transcriptional regulator
M1C60_13370	COG3284	Transcriptional regulator
M1C60_13390	COG1349	DNA-binding transcription factor activity
M1C60_13410	COG1959	2 iron, 2 sulfur cluster binding
M1C60_13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1C60_13430	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_13435	COG0022	dehydrogenase e1 component
M1C60_13440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_13450	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_13455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_13455	COG0456	acetyltransferase
M1C60_13490	COG0517	IMP dehydrogenase activity
M1C60_13490	COG4175	Glycine betaine
M1C60_13515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M1C60_13520	COG2153	protein acetylation
M1C60_13525	COG3397	chitin binding
M1C60_13540	COG2205	protein histidine kinase activity
M1C60_13565	COG2333	competence protein COMEC
M1C60_13565	COG0658	competence protein
M1C60_13615	COG3973	AAA domain
M1C60_13630	COG2105	PFAM AIG2 family protein
M1C60_13635	COG0514	ATP-dependent DNA helicase (RecQ)
M1C60_13655	COG4637	Psort location Cytoplasmic, score
M1C60_13680	COG3397	chitin binding
M1C60_13695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1C60_13700	COG1115	amino acid carrier protein
M1C60_13705	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1C60_13720	COG3938	Belongs to the proline racemase family
M1C60_13725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_13765	COG0586	Pfam SNARE associated Golgi protein
M1C60_13780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1C60_13785	COG0519	Catalyzes the synthesis of GMP from XMP
M1C60_13790	COG4166	transmembrane transport
M1C60_13800	COG4948	Mandelate Racemase Muconate Lactonizing
M1C60_13845	COG2936	dipeptidyl-peptidase activity
M1C60_13850	COG5002	protein histidine kinase activity
M1C60_13900	COG1307	EDD domain protein, DegV family
M1C60_13920	COG2814	Major facilitator Superfamily
M1C60_13930	COG1664	Polymer-forming cytoskeletal
M1C60_13935	COG0789	Transcriptional regulator
M1C60_13940	COG4533	DNA binding
M1C60_13945	COG0477	Major facilitator Superfamily
M1C60_13945	COG2814	Major facilitator Superfamily
M1C60_13965	COG2261	transglycosylase associated protein
M1C60_13980	COG2226	methyltransferase
M1C60_14015	COG0436	Aminotransferase
M1C60_14020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M1C60_14025	COG5146	pantothenate kinase activity
M1C60_14045	COG1131	(ABC) transporter
M1C60_14090	COG0628	permease
M1C60_14105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_14115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_14120	COG1116	anion transmembrane transporter activity
M1C60_14140	COG2816	NAD+ diphosphatase activity
M1C60_14160	COG2746	aminoglycoside 3-N-acetyltransferase activity
M1C60_14185	COG0697	spore germination
M1C60_14190	COG2318	DinB family
M1C60_14210	COG4912	Dna alkylation repair
M1C60_14230	COG0861	Integral membrane protein TerC family
M1C60_14235	COG1368	sulfuric ester hydrolase activity
M1C60_14240	COG0488	(ABC) transporter
M1C60_14255	COG1309	transcriptional regulator
M1C60_14270	COG0287	Prephenate dehydrogenase
M1C60_14275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1C60_14280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M1C60_14285	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M1C60_14285	COG1605	Chorismate mutase
M1C60_14330	COG1595	DNA-templated transcription, initiation
M1C60_14355	COG1879	ABC-type sugar transport system periplasmic component
M1C60_14365	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1C60_14375	COG2390	Transcriptional regulator
M1C60_14410	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_14430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_14440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M1C60_14445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_14450	COG4187	Peptidase family M20/M25/M40
M1C60_14455	COG1414	Transcriptional regulator
M1C60_14460	COG0833	amino acid
M1C60_14465	COG1690	Belongs to the RtcB family
M1C60_14475	COG1785	Belongs to the alkaline phosphatase family
M1C60_14485	COG3655	Transcriptional regulator
M1C60_14500	COG4377	Putative membrane peptidase family (DUF2324)
M1C60_14510	COG3279	Response regulator of the LytR AlgR family
M1C60_14520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_14525	COG0346	lactoylglutathione lyase activity
M1C60_14545	COG0714	Associated with various cellular activities
M1C60_14570	COG0463	Glycosyl transferase, family 2
M1C60_14590	COG0463	Glycosyl transferase, family 2
M1C60_14600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1C60_14605	COG0753	catalase activity
M1C60_14615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1C60_14640	COG0714	Associated with various cellular activities
M1C60_14650	COG0778	Nitroreductase
M1C60_14655	COG1846	Transcriptional regulator
M1C60_14690	COG1725	Transcriptional regulator
M1C60_14700	COG0577	efflux transmembrane transporter activity
M1C60_14700	COG1136	(ABC) transporter
M1C60_14725	COG2207	Transcriptional regulator
M1C60_14730	COG0456	acetyltransferase
M1C60_14750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_14770	COG0642	Histidine kinase
M1C60_14775	COG0745	RESPONSE REGULATOR receiver
M1C60_14780	COG0596	Alpha beta hydrolase
M1C60_14810	COG0730	response to heat
M1C60_14820	COG0833	amino acid
M1C60_14830	COG4335	DNA alkylation repair
M1C60_14870	COG0768	penicillin binding
M1C60_14880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1C60_14915	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M1C60_14920	COG1414	Transcriptional regulator
M1C60_14935	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_14940	COG0640	Transcriptional regulator
M1C60_14950	COG1960	acyl-CoA dehydrogenase activity
M1C60_14965	COG3314	Sporulation integral membrane protein YlbJ
M1C60_14980	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M1C60_14995	COG3848	Pyruvate phosphate dikinase
M1C60_14995	COG0574	Belongs to the PEP-utilizing enzyme family
M1C60_15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_15015	COG5577	PFAM Coat F domain
M1C60_15020	COG3403	YqcI/YcgG family
M1C60_15025	COG1280	lysine exporter protein (LysE YggA)
M1C60_15060	COG1063	alcohol dehydrogenase
M1C60_15075	COG1027	Aspartate ammonia-lyase
M1C60_15080	COG0252	asparaginase activity
M1C60_15085	COG1396	sequence-specific DNA binding
M1C60_15095	COG0322	excinuclease ABC activity
M1C60_15100	COG0531	amino acid
M1C60_15105	COG1114	Component of the transport system for branched-chain amino acids
M1C60_15110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_15120	COG0281	malic enzyme
M1C60_15135	COG0531	amino acid
M1C60_15145	COG0784	Response regulator, receiver
M1C60_15155	COG2066	Belongs to the glutaminase family
M1C60_15160	COG1115	amino acid carrier protein
M1C60_15190	COG0737	Belongs to the 5'-nucleotidase family
M1C60_15195	COG0753	catalase activity
M1C60_15200	COG2267	carboxylic ester hydrolase activity
M1C60_15205	COG1335	isochorismatase
M1C60_15225	COG0583	DNA-binding transcription factor activity
M1C60_15275	COG0415	Belongs to the DNA photolyase family
M1C60_15280	COG0288	reversible hydration of carbon dioxide
M1C60_15290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1C60_15295	COG5609	conserved protein (DUF2294)
M1C60_15310	COG1575	Belongs to the MenA family. Type 1 subfamily
M1C60_15315	COG2267	carboxylic ester hydrolase activity
M1C60_15320	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1C60_15325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1C60_15330	COG1121	(ABC) transporter
M1C60_15360	COG0798	PFAM Bile acid sodium symporter
M1C60_15365	COG0346	lactoylglutathione lyase activity
M1C60_15370	COG0640	Transcriptional regulator
M1C60_15385	COG0443	Heat shock 70 kDa protein
M1C60_15400	COG1522	sequence-specific DNA binding
M1C60_15415	COG0346	lactoylglutathione lyase activity
M1C60_15435	COG2169	Transcriptional regulator
M1C60_15440	COG2169	Transcriptional regulator
M1C60_15485	COG2814	Major facilitator Superfamily
M1C60_15510	COG0745	RESPONSE REGULATOR receiver
M1C60_15515	COG3850	Histidine kinase
M1C60_15515	COG5002	protein histidine kinase activity
M1C60_15540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1C60_15560	COG1476	TRANSCRIPTIONal
M1C60_15575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_15580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1C60_15590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_15595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M1C60_15610	COG1136	(ABC) transporter
M1C60_15615	COG0577	efflux transmembrane transporter activity
M1C60_15630	COG5002	protein histidine kinase activity
M1C60_15630	COG3850	Histidine kinase
M1C60_15640	COG2364	Membrane
M1C60_15645	COG1846	Transcriptional regulator
M1C60_15655	COG2808	Putative FMN-binding domain
M1C60_15660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_15665	COG2271	Major facilitator Superfamily
M1C60_15670	COG1556	Lactate utilization protein
M1C60_15675	COG1139	Iron-sulfur cluster binding protein
M1C60_15685	COG0583	DNA-binding transcription factor activity
M1C60_15695	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_15720	COG0673	inositol 2-dehydrogenase activity
M1C60_15725	COG0561	phosphatase activity
M1C60_15735	COG1609	Transcriptional regulator
M1C60_15740	COG0457	Tetratricopeptide repeat
M1C60_15760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_15790	COG0534	Mate efflux family protein
M1C60_15810	COG2814	Major facilitator Superfamily
M1C60_15815	COG1309	transcriptional regulator
M1C60_15830	COG0814	amino acid
M1C60_15835	COG1760	l-serine dehydratase
M1C60_15840	COG1760	l-serine dehydratase
M1C60_15850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1C60_15855	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
M1C60_15865	COG1335	isochorismatase
M1C60_15870	COG1522	sequence-specific DNA binding
M1C60_15875	COG0531	amino acid
M1C60_15895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1C60_15915	COG1595	DNA-templated transcription, initiation
M1C60_15930	COG0662	Cupin 2, conserved barrel domain protein
M1C60_15935	COG2207	Transcriptional regulator
M1C60_15935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_15985	COG0477	Major facilitator Superfamily
M1C60_15995	COG1846	Transcriptional regulator
M1C60_16000	COG2814	Major facilitator Superfamily
M1C60_16010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_16015	COG1131	(ABC) transporter
M1C60_16035	COG2076	Multidrug Resistance protein
M1C60_16040	COG1309	transcriptional regulator
M1C60_16050	COG2031	fatty acid transporter
M1C60_16060	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_16090	COG1122	ATPase activity
M1C60_16095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1C60_16110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1C60_16115	COG1288	antiporter activity
M1C60_16120	COG2356	endonuclease I
M1C60_16135	COG3620	sequence-specific DNA binding
M1C60_16140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_16145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1C60_16150	COG0124	histidyl-tRNA synthetase
M1C60_16165	COG1733	regulation of RNA biosynthetic process
M1C60_16170	COG0778	Nitroreductase
M1C60_16190	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_16200	COG1131	(ABC) transporter
M1C60_16225	COG1011	Hydrolase
M1C60_16235	COG2365	Tyrosine phosphatase family
M1C60_16260	COG0346	lactoylglutathione lyase activity
M1C60_16265	COG1940	carbohydrate kinase activity
M1C60_16270	COG0738	Major facilitator superfamily
M1C60_16275	COG0110	maltose O-acetyltransferase activity
M1C60_16285	COG0577	efflux transmembrane transporter activity
M1C60_16285	COG1136	(ABC) transporter
M1C60_16300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M1C60_16305	COG0628	permease
M1C60_16325	COG2226	methyltransferase
M1C60_16335	COG0477	Major facilitator Superfamily
M1C60_16365	COG1253	flavin adenine dinucleotide binding
M1C60_16370	COG0789	Transcriptional regulator
M1C60_16375	COG0697	spore germination
M1C60_16380	COG1357	PFAM Pentapeptide repeats (8 copies)
M1C60_16385	COG3813	Protein conserved in bacteria
M1C60_16390	COG2706	6-phosphogluconolactonase activity
M1C60_16395	COG1070	Carbohydrate kinase
M1C60_16405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1C60_16410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M1C60_16420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1C60_16425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1C60_16430	COG0604	alcohol dehydrogenase
M1C60_16435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_16445	COG0604	alcohol dehydrogenase
M1C60_16445	COG3321	synthase
M1C60_16450	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_16475	COG0656	L-ascorbic acid biosynthetic process
M1C60_16480	COG2814	Major facilitator Superfamily
M1C60_16495	COG0346	lactoylglutathione lyase activity
M1C60_16500	COG0814	amino acid
M1C60_16525	COG1393	Belongs to the ArsC family
M1C60_16530	COG1733	regulation of RNA biosynthetic process
M1C60_16535	COG2188	Transcriptional regulator
M1C60_16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M1C60_16550	COG1733	regulation of RNA biosynthetic process
M1C60_16555	COG1733	regulation of RNA biosynthetic process
M1C60_16570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_16590	COG0384	phenazine biosynthesis protein PhzF
M1C60_16600	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_16610	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_16620	COG1733	regulation of RNA biosynthetic process
M1C60_16650	COG1191	sigma factor activity
M1C60_16665	COG1309	transcriptional regulator
M1C60_16685	COG3152	Membrane
M1C60_16710	COG1151	hydroxylamine reductase activity
M1C60_16720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_16725	COG3757	hydrolase, family 25
M1C60_16725	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_16760	COG2072	flavoprotein involved in K transport
M1C60_16795	COG0604	alcohol dehydrogenase
M1C60_16800	COG1113	amino acid transport
M1C60_16805	COG2814	Major facilitator Superfamily
M1C60_16835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_16840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_16875	COG3739	integral membrane protein
M1C60_16880	COG0384	phenazine biosynthesis protein PhzF
M1C60_16910	COG0583	DNA-binding transcription factor activity
M1C60_16930	COG1193	negative regulation of DNA recombination
M1C60_16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_16990	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_17015	COG0640	Transcriptional regulator
M1C60_17020	COG0604	alcohol dehydrogenase
M1C60_17040	COG2808	Putative FMN-binding domain
M1C60_17045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_17055	COG0385	Bile acid
M1C60_17060	COG0277	FAD linked oxidase domain protein
M1C60_17090	COG1216	Glycosyl transferase, family 2
M1C60_17095	COG1024	Enoyl-CoA hydratase
M1C60_17105	COG1285	pathogenesis
M1C60_17120	COG2514	catechol 2,3-dioxygenase activity
M1C60_17125	COG2720	vancomycin resistance protein
M1C60_17165	COG0716	FMN binding
M1C60_17195	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_17205	COG0165	Argininosuccinate lyase
M1C60_17220	COG4145	pantothenate transmembrane transporter activity
M1C60_17230	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_17235	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_17245	COG1657	PFAM Prenyltransferase squalene oxidase
M1C60_17250	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M1C60_17255	COG2962	Rard protein
M1C60_17260	COG3326	Membrane
M1C60_17275	COG0489	protein tyrosine kinase activity
M1C60_17285	COG0314	molybdopterin synthase activity
M1C60_17290	COG0303	'Molybdopterin
M1C60_17295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_17300	COG2116	formate transmembrane transporter activity
M1C60_17310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1C60_17315	COG5609	conserved protein (DUF2294)
M1C60_17320	COG2427	Protein of unknown function (DUF1641)
M1C60_17325	COG3383	formate dehydrogenase (NAD+) activity
M1C60_17335	COG0697	spore germination
M1C60_17375	COG2226	methyltransferase
M1C60_17380	COG4166	transmembrane transport
M1C60_17390	COG4166	transmembrane transport
M1C60_17395	COG1301	dicarboxylic acid transport
M1C60_17400	COG1316	TRANSCRIPTIONal
M1C60_17410	COG1595	DNA-templated transcription, initiation
M1C60_17430	COG1131	(ABC) transporter
M1C60_17440	COG0673	inositol 2-dehydrogenase activity
M1C60_17445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1C60_17450	COG0187	DNA topoisomerase II activity
M1C60_17455	COG1832	CoA-binding protein
M1C60_17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_17465	COG0745	RESPONSE REGULATOR receiver
M1C60_17480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_17485	COG4841	protein insertion into membrane
M1C60_17490	COG0824	Thioesterase
M1C60_17520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_17530	COG2274	protein secretion by the type I secretion system
M1C60_17535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1C60_17575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_17590	COG0183	Belongs to the thiolase family
M1C60_17595	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_17600	COG1268	BioY protein
M1C60_17605	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_17655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_17665	COG5002	protein histidine kinase activity
M1C60_17670	COG0400	carboxylic ester hydrolase activity
M1C60_17675	COG0346	lactoylglutathione lyase activity
M1C60_17680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_17685	COG0069	glutamate synthase activity
M1C60_17690	COG1902	pentaerythritol trinitrate reductase activity
M1C60_17695	COG1329	Transcriptional regulator
M1C60_17700	COG0010	Belongs to the arginase family
M1C60_17725	COG2226	methyltransferase
M1C60_17760	COG4846	Membrane protein involved in cytochrome C biogenesis
M1C60_17765	COG0785	Cytochrome C biogenesis protein
M1C60_17775	COG0583	DNA-binding transcription factor activity
M1C60_17780	COG1380	Effector of murein hydrolase LrgA
M1C60_17785	COG1346	cytolysis
M1C60_17810	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1C60_17810	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_17825	COG1132	(ABC) transporter
M1C60_17830	COG1132	(ABC) transporter
M1C60_17860	COG3639	organic phosphonate transmembrane transporter activity
M1C60_17865	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
M1C60_17885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1C60_17905	COG1695	Transcriptional regulator
M1C60_17945	COG1388	LysM domain
M1C60_17945	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_17945	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1C60_17950	COG4824	toxin secretion phage lysis holin
M1C60_18105	COG1595	DNA-templated transcription, initiation
M1C60_18150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
M1C60_18230	COG1396	sequence-specific DNA binding
M1C60_18255	COG0174	glutamine synthetase
M1C60_18260	COG0789	Transcriptional regulator
M1C60_18265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M1C60_18275	COG2860	membrane
M1C60_18280	COG0464	growth
M1C60_18310	COG1388	LysM domain
M1C60_18310	COG3584	3D domain protein
M1C60_18315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1C60_18315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1C60_18315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_18320	COG1105	Belongs to the carbohydrate kinase PfkB family
M1C60_18325	COG1349	DNA-binding transcription factor activity
M1C60_18335	COG2322	membrane
M1C60_18345	COG1113	amino acid transport
M1C60_18360	COG1408	metallophosphoesterase
M1C60_18365	COG2116	formate transmembrane transporter activity
M1C60_18375	COG2217	Heavy metal translocating P-type atpase
M1C60_18380	COG2608	mercury ion transmembrane transporter activity
M1C60_18385	COG1937	Protein conserved in bacteria
M1C60_18395	COG2819	hydrolase of the alpha beta superfamily
M1C60_18400	COG1120	ATPase activity
M1C60_18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_18415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_18420	COG0708	Exodeoxyribonuclease III
M1C60_18425	COG2169	Transcriptional regulator
M1C60_18430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1C60_18435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M1C60_18445	COG2364	Membrane
M1C60_18460	COG2267	carboxylic ester hydrolase activity
M1C60_18465	COG0346	lactoylglutathione lyase activity
M1C60_18470	COG5001	Diguanylate cyclase
M1C60_18470	COG3300	MHYT domain
M1C60_18485	COG1346	cytolysis
M1C60_18490	COG1380	Effector of murein hydrolase LrgA
M1C60_18495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_18500	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_18500	COG0596	Alpha beta hydrolase
M1C60_18505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_18525	COG1404	Belongs to the peptidase S8 family
M1C60_18530	COG3773	Cell wall hydrolase
M1C60_18535	COG0562	UDP-galactopyranose mutase
M1C60_18540	COG1368	sulfuric ester hydrolase activity
M1C60_18545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_18555	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M1C60_18580	COG1131	(ABC) transporter
M1C60_18600	COG4550	Control of competence regulator ComK, YlbF/YmcA
M1C60_18605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1C60_18610	COG1013	pyruvate-flavodoxin oxidoreductase activity
M1C60_18615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M1C60_18615	COG0674	pyruvate-flavodoxin oxidoreductase activity
M1C60_18625	COG2359	stage V sporulation protein S
M1C60_18630	COG1692	metallophosphoesterase
M1C60_18655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1C60_18660	COG1426	Protein conserved in bacteria
M1C60_18675	COG0300	oxidoreductase activity
M1C60_18680	COG0612	Peptidase, M16
M1C60_18685	COG0612	Peptidase, M16
M1C60_18690	COG1079	Belongs to the binding-protein-dependent transport system permease family
M1C60_18700	COG3845	ABC transporter
M1C60_18705	COG1744	ABC transporter substrate-binding protein PnrA-like
M1C60_18710	COG2188	Transcriptional regulator
M1C60_18715	COG1674	ftsk spoiiie
M1C60_18725	COG0740	serine-type endopeptidase activity
M1C60_18730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_18740	COG0527	aspartate kinase activity
M1C60_18745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1C60_18750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1C60_18755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1C60_18760	COG1873	PFAM PRC-barrel domain
M1C60_18765	COG0612	Peptidase, M16
M1C60_18770	COG0726	polysaccharide deacetylase
M1C60_18785	COG0196	riboflavin kinase activity
M1C60_18790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1C60_18800	COG1550	Protein conserved in bacteria
M1C60_18810	COG1358	cellular component organization or biogenesis
M1C60_18815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M1C60_18820	COG0195	Participates in both transcription termination and antitermination
M1C60_18840	COG0750	zinc metalloprotease
M1C60_18850	COG4589	Belongs to the CDS family
M1C60_18855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1C60_18865	COG0528	UMP kinase activity
M1C60_18895	COG4974	Belongs to the 'phage' integrase family
M1C60_18905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1C60_18915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M1C60_18955	COG1837	Belongs to the UPF0109 family
M1C60_18965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1C60_18975	COG0552	protein localization to endoplasmic reticulum
M1C60_18980	COG1196	nuclear chromosome segregation
M1C60_18990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_18995	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_19000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1C60_19015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1C60_19020	COG1461	Dihydroxyacetone kinase
M1C60_19025	COG1302	Protein conserved in bacteria
M1C60_19040	COG1564	THIamine pyrophosphokinase
M1C60_19045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1C60_19050	COG1162	GTPase activity
M1C60_19055	COG0515	serine threonine protein kinase
M1C60_19055	COG2815	serine threonine protein kinase
M1C60_19060	COG0631	protein serine/threonine phosphatase activity
M1C60_19070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M1C60_19070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M1C60_19080	COG0242	peptide deformylase activity
M1C60_19085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1C60_19090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1C60_19110	COG1561	YicC-like family, N-terminal region
M1C60_19115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1C60_19125	COG0006	proline dipeptidase activity
M1C60_19140	COG3069	C4-dicarboxylate transmembrane transporter activity
M1C60_19205	COG0564	pseudouridine synthase activity
M1C60_19225	COG3599	regulation of cell shape
M1C60_19230	COG2302	S4 RNA-binding domain
M1C60_19235	COG0762	integral membrane protein
M1C60_19245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M1C60_19250	COG1496	oxidoreductase activity
M1C60_19255	COG1873	PFAM PRC-barrel domain
M1C60_19260	COG1191	sigma factor activity
M1C60_19265	COG1191	sigma factor activity
M1C60_19275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1C60_19280	COG0849	cell division
M1C60_19285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1C60_19290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1C60_19300	COG0772	Belongs to the SEDS family
M1C60_19315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1C60_19320	COG0768	penicillin binding
M1C60_19325	COG0768	penicillin binding
M1C60_19330	COG4839	cell division protein FtsL
M1C60_19345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1C60_19360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M1C60_19365	COG1399	metal-binding, possibly nucleic acid-binding protein
M1C60_19415	COG4824	toxin secretion phage lysis holin
M1C60_19510	COG1802	Transcriptional regulator
M1C60_19510	COG4626	Terminase
M1C60_19535	COG0582	viral genome integration into host DNA
M1C60_19600	COG0756	dUTP diphosphatase activity
M1C60_19615	COG1191	sigma factor activity
M1C60_19640	COG1484	DNA-dependent DNA replication
M1C60_19670	COG1396	sequence-specific DNA binding
M1C60_19685	COG1396	sequence-specific DNA binding
M1C60_19700	COG0582	viral genome integration into host DNA
M1C60_19710	COG3480	Lon protease (S16) C-terminal proteolytic domain
M1C60_19715	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1C60_19720	COG3314	Sporulation integral membrane protein YlbJ
M1C60_19730	COG0742	ribosomal rna small subunit methyltransferase
M1C60_19745	COG3679	Belongs to the UPF0342 family
M1C60_19750	COG0406	alpha-ribazole phosphatase activity
M1C60_19765	COG2340	Cysteine-rich secretory protein family
M1C60_19780	COG3336	cytochrome c oxidase
M1C60_19815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M1C60_19820	COG0772	Belongs to the SEDS family
M1C60_19830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M1C60_19835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M1C60_19845	COG4896	Protein conserved in bacteria
M1C60_19860	COG1217	gtp-binding protein TYPA
M1C60_19870	COG0483	inositol monophosphate 1-phosphatase activity
M1C60_19890	COG1982	Orn Lys Arg decarboxylase major
M1C60_19935	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_19940	COG0022	dehydrogenase e1 component
M1C60_19945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_19955	COG0242	peptide deformylase activity
M1C60_19960	COG0561	phosphatase activity
M1C60_19970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_19975	COG0569	domain protein
M1C60_19995	COG0583	DNA-binding transcription factor activity
M1C60_20000	COG0517	IMP dehydrogenase activity
M1C60_20010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M1C60_20020	COG4703	Protein of unknown function (DUF1797)
M1C60_20035	COG2200	EAL domain
M1C60_20040	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_20045	COG1408	metallophosphoesterase
M1C60_20055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M1C60_20090	COG2814	Major facilitator Superfamily
M1C60_20110	COG3209	COG3209 Rhs family protein
M1C60_20120	COG2205	protein histidine kinase activity
M1C60_20130	COG0436	Aminotransferase
M1C60_20135	COG1609	Transcriptional regulator
M1C60_20140	COG3833	ABC-type maltose transport systems, permease component
M1C60_20145	COG1175	transmembrane transport
M1C60_20150	COG2182	Extracellular solute-binding protein
M1C60_20160	COG0366	Alpha amylase catalytic
M1C60_20165	COG3842	ATPase activity
M1C60_20205	COG0183	Belongs to the thiolase family
M1C60_20240	COG1695	Transcriptional regulator
M1C60_20245	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_20255	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M1C60_20265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1C60_20270	COG0436	Aminotransferase
M1C60_20290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M1C60_20310	COG2199	diguanylate cyclase activity
M1C60_20315	COG0778	Nitroreductase
M1C60_20340	COG2190	(PTS) system
M1C60_20340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_20340	COG1263	PTS System
M1C60_20345	COG3711	transcriptional antiterminator
M1C60_20355	COG2188	Transcriptional regulator
M1C60_20365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M1C60_20390	COG1547	Domain of unknown function (DUF309)
M1C60_20395	COG0456	acetyltransferase
M1C60_20405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1C60_20410	COG4086	secreted protein
M1C60_20415	COG0561	phosphatase activity
M1C60_20420	COG0697	spore germination
M1C60_20435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_20460	COG0733	neurotransmitter:sodium symporter activity
M1C60_20480	COG1686	Belongs to the peptidase S11 family
M1C60_20485	COG1725	Transcriptional regulator
M1C60_20490	COG1131	(ABC) transporter
M1C60_20505	COG1846	Transcriptional regulator
M1C60_20520	COG0598	Magnesium transport protein CorA
M1C60_20545	COG4974	Belongs to the 'phage' integrase family
M1C60_20555	COG0735	belongs to the Fur family
M1C60_20560	COG1300	Membrane
M1C60_20580	COG0667	Aldo Keto reductase
M1C60_20585	COG0656	L-ascorbic acid biosynthetic process
M1C60_20590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_20590	COG0456	acetyltransferase
M1C60_20600	COG1525	nuclease
M1C60_20600	COG4085	toxin activity
M1C60_20600	COG0737	Belongs to the 5'-nucleotidase family
M1C60_20610	COG0596	Alpha beta hydrolase
M1C60_20615	COG2056	Na+-H+ antiporter family
M1C60_20620	COG1609	Transcriptional regulator
M1C60_20625	COG0456	acetyltransferase
M1C60_20630	COG1073	alpha beta
M1C60_20645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1C60_20645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1C60_20650	COG0307	riboflavin synthase, alpha
M1C60_20675	COG4106	trans-aconitate 2-methyltransferase activity
M1C60_20680	COG1073	alpha beta
M1C60_20680	COG2226	methyltransferase
M1C60_20695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_20705	COG1757	Na H antiporter
M1C60_20710	COG0737	Belongs to the 5'-nucleotidase family
M1C60_20720	COG1522	sequence-specific DNA binding
M1C60_20740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1C60_20750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1C60_20765	COG0300	oxidoreductase activity
M1C60_20775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_20780	COG1760	l-serine dehydratase
M1C60_20785	COG1760	l-serine dehydratase
M1C60_20805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_20815	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1C60_20820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_20835	COG1376	ErfK ybiS ycfS ynhG family protein
M1C60_20840	COG4129	membrane
M1C60_20845	COG1126	abc transporter atp-binding protein
M1C60_20850	COG0765	amino acid transport
M1C60_20855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_20870	COG2816	NAD+ diphosphatase activity
M1C60_20875	COG0772	Belongs to the SEDS family
M1C60_20880	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_20885	COG0022	dehydrogenase e1 component
M1C60_20890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_20895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1C60_20910	COG0280	phosphate acetyltransferase
M1C60_20915	COG3290	protein histidine kinase activity
M1C60_20915	COG3829	transcription factor binding
M1C60_20925	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_20930	COG3093	addiction module antidote protein HigA
M1C60_20940	COG0745	RESPONSE REGULATOR receiver
M1C60_20945	COG0750	zinc metalloprotease
M1C60_20950	COG0497	DNA recombination
M1C60_20960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M1C60_20970	COG0142	geranyltranstransferase activity
M1C60_20995	COG1302	Protein conserved in bacteria
M1C60_21000	COG0439	Biotin carboxylase
M1C60_21005	COG0511	ligase activity, forming carbon-carbon bonds
M1C60_21050	COG3854	ATPases associated with a variety of cellular activities
M1C60_21075	COG0006	proline dipeptidase activity
M1C60_21090	COG3872	metal-dependent enzyme
M1C60_21100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1C60_21120	COG0095	Lipoate-protein ligase
M1C60_21125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_21130	COG1609	Transcriptional regulator
M1C60_21140	COG2076	Multidrug Resistance protein
M1C60_21145	COG2076	Multidrug Resistance protein
M1C60_21185	COG1725	Transcriptional regulator
M1C60_21215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1C60_21270	COG4970	Tfp pilus assembly protein FimT
M1C60_21280	COG1459	type II secretion system
M1C60_21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1C60_21335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M1C60_21340	COG0646	methionine synthase
M1C60_21340	COG1410	methionine synthase
M1C60_21345	COG0646	methionine synthase
M1C60_21345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1C60_21350	COG0626	cystathionine gamma-synthase activity
M1C60_21355	COG0626	cystathionine gamma-synthase activity
M1C60_21375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_21385	COG1940	carbohydrate kinase activity
M1C60_21390	COG4483	Protein conserved in bacteria
M1C60_21395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1C60_21400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M1C60_21405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1C60_21410	COG0704	Plays a role in the regulation of phosphate uptake
M1C60_21420	COG0581	inorganic phosphate transmembrane transporter activity
M1C60_21425	COG0573	inorganic phosphate transmembrane transporter activity
M1C60_21430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1C60_21435	COG0768	penicillin binding
M1C60_21440	COG0477	Major facilitator Superfamily
M1C60_21445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_21470	COG0735	belongs to the Fur family
M1C60_21475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1C60_21480	COG1121	(ABC) transporter
M1C60_21485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_21515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1C60_21520	COG2384	SAM-dependent methyltransferase
M1C60_21525	COG2010	Cytochrome c
M1C60_21530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M1C60_21535	COG0358	DNA primase activity
M1C60_21545	COG0517	IMP dehydrogenase activity
M1C60_21560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1C60_21565	COG0295	cytidine deaminase activity
M1C60_21570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M1C60_21580	COG1480	7TM receptor with intracellular HD hydrolase
M1C60_21585	COG1702	phosphate starvation-inducible protein PhoH
M1C60_21600	COG1610	YqeY-like protein
M1C60_21605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M1C60_21610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1C60_21615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1C60_21645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1C60_21650	COG1733	regulation of RNA biosynthetic process
M1C60_21675	COG1466	dna polymerase III delta subunit
M1C60_21685	COG2333	competence protein COMEC
M1C60_21685	COG0658	competence protein
M1C60_21690	COG2131	deaminase
M1C60_21695	COG1555	photosystem II stabilization
M1C60_21695	COG1596	polysaccharide export
M1C60_21700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_21705	COG2226	methyltransferase
M1C60_21710	COG0799	negative regulation of ribosome biogenesis
M1C60_21715	COG1713	HD superfamily hydrolase involved in NAD metabolism
M1C60_21725	COG1534	Rna-binding protein
M1C60_21735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M1C60_21740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M1C60_21765	COG1595	DNA-templated transcription, initiation
M1C60_21775	COG0778	Nitroreductase
M1C60_21780	COG2357	RelA SpoT domain protein
M1C60_21790	COG1785	Belongs to the alkaline phosphatase family
M1C60_21800	COG2267	carboxylic ester hydrolase activity
M1C60_21835	COG1404	Belongs to the peptidase S8 family
M1C60_21840	COG3186	Phenylalanine-4-hydroxylase
M1C60_21855	COG2259	Doxx family
M1C60_21895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_21905	COG1454	alcohol dehydrogenase
M1C60_21905	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_21910	COG0626	cystathionine gamma-synthase activity
M1C60_21915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_21940	COG0768	penicillin binding
M1C60_21955	COG0826	peptidase U32
M1C60_21960	COG0826	peptidase U32
M1C60_21965	COG4122	O-methyltransferase activity
M1C60_21970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1C60_21990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_22000	COG0628	permease
M1C60_22020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1C60_22030	COG0482	sulfurtransferase activity
M1C60_22035	COG1104	cysteine desulfurase activity
M1C60_22040	COG1959	2 iron, 2 sulfur cluster binding
M1C60_22045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1C60_22055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1C60_22080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1C60_22090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M1C60_22090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1C60_22095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1C60_22100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1C60_22100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1C60_22110	COG2244	polysaccharide biosynthetic process
M1C60_22115	COG2323	membrane
M1C60_22125	COG1862	Preprotein translocase
M1C60_22155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M1C60_22165	COG0697	spore germination
M1C60_22170	COG0697	spore germination
M1C60_22175	COG0640	Transcriptional regulator
M1C60_22200	COG0157	Belongs to the NadC ModD family
M1C60_22205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M1C60_22210	COG1104	cysteine desulfurase activity
M1C60_22215	COG1827	regulation of RNA biosynthetic process
M1C60_22220	COG2258	MOSC domain
M1C60_22225	COG0077	Prephenate dehydratase
M1C60_22230	COG0577	efflux transmembrane transporter activity
M1C60_22235	COG0577	efflux transmembrane transporter activity
M1C60_22240	COG1136	(ABC) transporter
M1C60_22250	COG0745	RESPONSE REGULATOR receiver
M1C60_22255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M1C60_22260	COG3290	protein histidine kinase activity
M1C60_22270	COG2868	ribosomal protein
M1C60_22280	COG1530	ribonuclease E activity
M1C60_22285	COG1994	Peptidase M50
M1C60_22290	COG0739	heme binding
M1C60_22295	COG2894	cell division
M1C60_22315	COG1077	Cell shape determining protein MreB Mrl
M1C60_22335	COG0285	dihydrofolate synthase activity
M1C60_22340	COG0525	valine-tRNA ligase activity
M1C60_22350	COG1388	LysM domain
M1C60_22360	COG0113	porphobilinogen synthase activity
M1C60_22365	COG1587	Uroporphyrinogen-III synthase
M1C60_22375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1C60_22385	COG1846	Transcriptional regulator
M1C60_22390	COG1764	response to oxidative stress
M1C60_22405	COG0470	DNA polymerase III
M1C60_22405	COG1067	ATP-dependent peptidase activity
M1C60_22450	COG0622	Phosphoesterase
M1C60_22465	COG5401	PFAM Sporulation and spore germination
M1C60_22485	COG1309	transcriptional regulator
M1C60_22500	COG2197	response regulator
M1C60_22505	COG2233	PERMEase
M1C60_22515	COG0402	S-adenosylhomocysteine deaminase activity
M1C60_22520	COG0402	S-adenosylhomocysteine deaminase activity
M1C60_22530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_22540	COG0444	Belongs to the ABC transporter superfamily
M1C60_22545	COG4608	Belongs to the ABC transporter superfamily
M1C60_22550	COG3275	phosphorelay sensor kinase activity
M1C60_22555	COG3279	Response regulator of the LytR AlgR family
M1C60_22570	COG1983	PspC domain protein
M1C60_22575	COG1396	sequence-specific DNA binding
M1C60_22580	COG0697	spore germination
M1C60_22590	COG1959	2 iron, 2 sulfur cluster binding
M1C60_22595	COG1668	transmembrane transport
M1C60_22600	COG4152	abc transporter atp-binding protein
M1C60_22605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M1C60_22615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1C60_22620	COG1876	peptidase activity
M1C60_22625	COG0824	Thioesterase
M1C60_22630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1C60_22635	COG1053	succinate dehydrogenase
M1C60_22640	COG2009	succinate dehydrogenase
M1C60_22645	COG1719	4-vinyl reductase, 4VR
M1C60_22655	COG3118	belongs to the thioredoxin family
M1C60_22660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M1C60_22665	COG2086	electron transfer activity
M1C60_22670	COG1024	Enoyl-CoA hydratase
M1C60_22680	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_22700	COG2318	DinB family
M1C60_22730	COG1131	(ABC) transporter
M1C60_22735	COG2205	protein histidine kinase activity
M1C60_22740	COG0745	RESPONSE REGULATOR receiver
M1C60_22750	COG4895	conserved protein (DUF2196)
M1C60_22755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M1C60_22770	COG4509	Sortase family
M1C60_22775	COG1120	ATPase activity
M1C60_22790	COG5386	Cell surface protein
M1C60_22800	COG5386	Cell surface protein
M1C60_22805	COG1114	Component of the transport system for branched-chain amino acids
M1C60_22810	COG1187	pseudouridine synthase activity
M1C60_22820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1C60_22820	COG1796	DNA polymerase
M1C60_22825	COG1286	toxin biosynthetic process
M1C60_22870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1C60_22880	COG1418	mRNA catabolic process
M1C60_22905	COG2814	Major facilitator Superfamily
M1C60_22910	COG1566	PFAM secretion protein HlyD family protein
M1C60_22915	COG1309	transcriptional regulator
M1C60_22920	COG1363	Peptidase, m42
M1C60_22945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_22955	COG1484	DNA-dependent DNA replication
M1C60_22960	COG3611	Membrane attachment protein
M1C60_22970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1C60_22975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1C60_22980	COG0237	dephospho-CoA kinase activity
M1C60_22985	COG1971	Probably functions as a manganese efflux pump
M1C60_22995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_22995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_23000	COG5002	protein histidine kinase activity
M1C60_23005	COG0745	RESPONSE REGULATOR receiver
M1C60_23025	COG0538	isocitrate dehydrogenase activity
M1C60_23030	COG0372	Belongs to the citrate synthase family
M1C60_23040	COG0628	permease
M1C60_23045	COG3030	protein affecting phage T7 exclusion by the F plasmid
M1C60_23070	COG1725	Transcriptional regulator
M1C60_23075	COG0281	malic enzyme
M1C60_23080	COG0587	DNA-directed DNA polymerase activity
M1C60_23095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M1C60_23115	COG4109	DRTGG domain
M1C60_23130	COG0006	proline dipeptidase activity
M1C60_23170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_23175	COG0662	Cupin 2, conserved barrel domain protein
M1C60_23185	COG1476	TRANSCRIPTIONal
M1C60_23200	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_23205	COG0589	response to stress
M1C60_23245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_23265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1C60_23270	COG0827	DNA restriction-modification system
M1C60_23275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M1C60_23280	COG3874	Sporulation protein YtfJ
M1C60_23295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M1C60_23305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_23320	COG1104	cysteine desulfurase activity
M1C60_23330	COG0583	DNA-binding transcription factor activity
M1C60_23335	COG0697	spore germination
M1C60_23345	COG1956	GAF domain-containing protein
M1C60_23350	COG0626	cystathionine gamma-synthase activity
M1C60_23380	COG1595	DNA-templated transcription, initiation
M1C60_23390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_23395	COG0454	-acetyltransferase
M1C60_23400	COG0517	IMP dehydrogenase activity
M1C60_23405	COG0123	including yeast histone deacetylase and acetoin utilization protein
M1C60_23415	COG0745	RESPONSE REGULATOR receiver
M1C60_23425	COG0666	response to abiotic stimulus
M1C60_23460	COG1609	Transcriptional regulator
M1C60_23465	COG4851	CamS sex pheromone cAM373 precursor
M1C60_23470	COG3118	belongs to the thioredoxin family
M1C60_23480	COG2309	aminopeptidase activity
M1C60_23500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_23515	COG1674	ftsk spoiiie
M1C60_23525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_23530	COG4848	Belongs to the UPF0354 family
M1C60_23535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_23540	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
M1C60_23545	COG1363	Peptidase, m42
M1C60_23555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_23570	COG0510	thiamine kinase activity
M1C60_23575	COG1523	belongs to the glycosyl hydrolase 13 family
M1C60_23590	COG1349	DNA-binding transcription factor activity
M1C60_23595	COG1187	pseudouridine synthase activity
M1C60_23600	COG2244	polysaccharide biosynthetic process
M1C60_23605	COG2081	HI0933 family
M1C60_23610	COG2814	Major facilitator Superfamily
M1C60_23620	COG3832	glyoxalase III activity
M1C60_23640	COG1329	Transcriptional regulator
M1C60_23650	COG4975	Glucose uptake
M1C60_23665	COG0314	molybdopterin synthase activity
M1C60_23670	COG1763	Mo-molybdopterin cofactor biosynthetic process
M1C60_23675	COG0303	'Molybdopterin
M1C60_23685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_23710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_23720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1C60_23760	COG2814	Major facilitator Superfamily
M1C60_23765	COG0475	glutathione-regulated potassium exporter activity
M1C60_23770	COG0490	domain, Protein
M1C60_23775	COG0582	viral genome integration into host DNA
M1C60_23785	COG1136	(ABC) transporter
M1C60_23805	COG1242	4 iron, 4 sulfur cluster binding
M1C60_23810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M1C60_23815	COG1131	(ABC) transporter
M1C60_23825	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_23845	COG2267	carboxylic ester hydrolase activity
M1C60_23850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1C60_23855	COG0671	phosphoesterase, PA-phosphatase related
M1C60_23860	COG0438	transferase activity, transferring glycosyl groups
M1C60_23870	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1C60_23925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1C60_23930	COG5002	protein histidine kinase activity
M1C60_23940	COG2267	carboxylic ester hydrolase activity
M1C60_23960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_23965	COG1116	anion transmembrane transporter activity
M1C60_23970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_23995	COG0494	nUDIX hydrolase
M1C60_24030	COG0288	reversible hydration of carbon dioxide
M1C60_24035	COG1271	oxidase subunit
M1C60_24040	COG1294	oxidase, subunit
M1C60_24060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_24085	COG1842	Phage shock protein A
M1C60_24115	COG5002	protein histidine kinase activity
M1C60_24120	COG0745	RESPONSE REGULATOR receiver
M1C60_24150	COG1597	lipid kinase activity
M1C60_24185	COG0586	Pfam SNARE associated Golgi protein
M1C60_24195	COG0577	efflux transmembrane transporter activity
M1C60_24200	COG1136	(ABC) transporter
M1C60_24205	COG2207	Transcriptional regulator
M1C60_24205	COG3708	Transcriptional regulator
M1C60_24210	COG0745	RESPONSE REGULATOR receiver
M1C60_24215	COG2205	protein histidine kinase activity
M1C60_24225	COG0577	efflux transmembrane transporter activity
M1C60_24230	COG1136	(ABC) transporter
M1C60_24250	COG2188	Transcriptional regulator
M1C60_24270	COG3964	amidohydrolase
M1C60_24300	COG4948	Mandelate Racemase Muconate Lactonizing
M1C60_24310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M1C60_24315	COG0596	Alpha beta hydrolase
M1C60_24320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M1C60_24325	COG1169	isochorismate synthase
M1C60_24330	COG1575	Belongs to the MenA family. Type 1 subfamily
M1C60_24335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1C60_24355	COG0058	SHG alpha-glucan phosphorylase activity
M1C60_24360	COG0297	glycogen (starch) synthase activity
M1C60_24365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M1C60_24480	COG0544	peptidyl-prolyl cis-trans isomerase activity
M1C60_24515	COG1285	pathogenesis
M1C60_24520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1C60_24530	COG0166	Belongs to the GPI family
M1C60_24535	COG2155	Conserved Protein
M1C60_24540	COG1098	S1 RNA binding domain
M1C60_24545	COG0436	Aminotransferase
M1C60_24550	COG1522	sequence-specific DNA binding
M1C60_24555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1C60_24560	COG2267	carboxylic ester hydrolase activity
M1C60_24570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M1C60_24590	COG5018	Exonuclease
M1C60_24595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_24615	COG2050	protein possibly involved in aromatic compounds catabolism
M1C60_24625	COG1268	BioY protein
M1C60_24635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1C60_24640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1C60_24655	COG3584	3D domain protein
M1C60_24670	COG1252	NADH dehydrogenase
M1C60_24685	COG3708	Transcriptional regulator
M1C60_24700	COG1683	Conserved Protein
M1C60_24720	COG0316	Belongs to the HesB IscA family
M1C60_24735	COG1252	NADH dehydrogenase
M1C60_24750	COG0390	transport system, permease component
M1C60_24755	COG2824	Alkylphosphonate utilization operon protein PhnA
M1C60_24795	COG4837	Protein of unknown function (DUF1462)
M1C60_24800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M1C60_24810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_24815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1C60_24825	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_24830	COG0647	UMP catabolic process
M1C60_24840	COG2445	Protein of unknown function DUF86
M1C60_24845	COG1494	fructose-1,6-bisphosphatase
M1C60_24860	COG4470	Protein conserved in bacteria
M1C60_24870	COG0789	Transcriptional regulator
M1C60_24875	COG4377	Putative membrane peptidase family (DUF2324)
M1C60_24900	COG0739	heme binding
M1C60_24910	COG3377	Domain of unknown function (DUF1805)
M1C60_24915	COG0737	Belongs to the 5'-nucleotidase family
M1C60_24920	COG1695	Transcriptional regulator
M1C60_24930	COG0719	Fe-S assembly protein
M1C60_24935	COG0822	iron-sulfur transferase activity
M1C60_24940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1C60_24945	COG0719	Fe-S assembly protein
M1C60_24950	COG0396	ATPase activity
M1C60_24955	COG1464	Belongs to the NlpA lipoprotein family
M1C60_24960	COG1464	Belongs to the NlpA lipoprotein family
M1C60_24965	COG2011	ABC-type metal ion transport system permease component
M1C60_24970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_24980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_24985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1C60_24995	COG1393	Belongs to the ArsC family
M1C60_25040	COG0039	L-malate dehydrogenase activity
M1C60_25065	COG1309	transcriptional regulator
M1C60_25070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_25075	COG1960	acyl-CoA dehydrogenase activity
M1C60_25080	COG0183	Belongs to the thiolase family
M1C60_25085	COG1024	Enoyl-CoA hydratase
M1C60_25085	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1C60_25095	COG1686	Belongs to the peptidase S11 family
M1C60_25110	COG0011	TIGRFAM Protein of
M1C60_25115	COG0840	transmembrane signaling receptor activity
M1C60_25135	COG2814	Major facilitator Superfamily
M1C60_25140	COG0531	amino acid
M1C60_25150	COG0706	membrane insertase activity
M1C60_25160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_25195	COG0586	Pfam SNARE associated Golgi protein
M1C60_25205	COG1376	ErfK ybiS ycfS ynhG family protein
M1C60_25210	COG0745	RESPONSE REGULATOR receiver
M1C60_25215	COG5002	protein histidine kinase activity
M1C60_25240	COG2151	metal-sulfur cluster biosynthetic enzyme
M1C60_25245	COG3227	Zinc metalloprotease (Elastase)
M1C60_25250	COG1741	Belongs to the pirin family
M1C60_25265	COG0475	glutathione-regulated potassium exporter activity
M1C60_25270	COG0490	domain, Protein
M1C60_25275	COG1115	amino acid carrier protein
M1C60_25280	COG0783	Belongs to the Dps family
M1C60_25295	COG1611	Belongs to the LOG family
M1C60_25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_25320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_25325	COG1115	amino acid carrier protein
M1C60_25330	COG1115	amino acid carrier protein
M1C60_25335	COG2910	NAD(P)H-binding
M1C60_25350	COG0656	L-ascorbic acid biosynthetic process
M1C60_25355	COG2814	Major facilitator Superfamily
M1C60_25360	COG1733	regulation of RNA biosynthetic process
M1C60_25370	COG1252	NADH dehydrogenase
M1C60_25375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1C60_25380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1C60_25390	COG0840	transmembrane signaling receptor activity
M1C60_25390	COG3290	protein histidine kinase activity
M1C60_25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1C60_25405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1C60_25420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_25475	COG0557	exoribonuclease II activity
M1C60_25480	COG1647	Serine aminopeptidase, S33
M1C60_25485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1C60_25490	COG1346	cytolysis
M1C60_25585	COG4695	Portal protein
M1C60_25610	COG4974	Belongs to the 'phage' integrase family
M1C60_25620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1C60_25625	COG0149	triose-phosphate isomerase activity
M1C60_25635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1C60_25650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M1C60_25675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_25690	COG2323	membrane
M1C60_25695	COG0740	serine-type endopeptidase activity
M1C60_25700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_25710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M1C60_25720	COG1051	belongs to the nudix hydrolase family
M1C60_25730	COG0492	ferredoxin-NADP+ reductase activity
M1C60_25735	COG0457	Tetratricopeptide repeat
M1C60_25740	COG0110	maltose O-acetyltransferase activity
M1C60_25760	COG1950	PFAM Membrane protein of
M1C60_25770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_25775	COG0556	nucleotide-excision repair
M1C60_25795	COG0789	Transcriptional regulator
M1C60_25820	COG2855	membrane
M1C60_25825	COG0583	DNA-binding transcription factor activity
M1C60_25835	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1C60_25840	COG0488	(ABC) transporter
M1C60_25850	COG1132	(ABC) transporter
M1C60_25855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_25860	COG0793	Belongs to the peptidase S41A family
M1C60_25860	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_25865	COG2177	Part of the ABC transporter FtsEX involved in
M1C60_25870	COG2884	Cell division ATP-binding protein ftsE
M1C60_25885	COG0653	protein targeting
M1C60_25890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M1C60_25895	COG1278	Cold shock
M1C60_25900	COG1040	competence protein
M1C60_25905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M1C60_25910	COG0791	NLP P60 protein
M1C60_25910	COG1388	LysM domain
M1C60_25915	COG1733	regulation of RNA biosynthetic process
M1C60_25920	COG1307	EDD domain protein, DegV family
M1C60_25925	COG1739	Uncharacterized protein family UPF0029
M1C60_25930	COG1316	TRANSCRIPTIONal
M1C60_25935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1C60_25940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1C60_25945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M1C60_25955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M1C60_25955	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M1C60_25970	COG3394	polysaccharide catabolic process
M1C60_25975	COG1486	melibiose metabolic process
M1C60_25980	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_25985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_25995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M1C60_26000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1C60_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_26015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_26020	COG1301	dicarboxylic acid transport
M1C60_26030	COG0346	lactoylglutathione lyase activity
M1C60_26035	COG1511	domain protein
M1C60_26040	COG0583	DNA-binding transcription factor activity
M1C60_26045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M1C60_26060	COG1271	oxidase subunit
M1C60_26065	COG1294	oxidase, subunit
M1C60_26070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_26080	COG1620	l-lactate permease
M1C60_26090	COG2389	metal-binding protein
M1C60_26100	COG1368	sulfuric ester hydrolase activity
M1C60_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_26125	COG1215	transferase activity, transferring glycosyl groups
M1C60_26130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_26135	COG1388	LysM domain
M1C60_26135	COG3584	3D domain protein
M1C60_26160	COG4715	Zinc finger, swim domain protein
M1C60_26205	COG0577	efflux transmembrane transporter activity
M1C60_26210	COG1136	(ABC) transporter
M1C60_26245	COG5002	protein histidine kinase activity
M1C60_26250	COG0745	RESPONSE REGULATOR receiver
M1C60_26255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1C60_26275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1C60_26280	COG1134	teichoic acid transport
M1C60_26285	COG1682	transport, permease protein
M1C60_26290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1C60_26335	COG1609	Transcriptional regulator
M1C60_26350	COG0739	heme binding
M1C60_26370	COG2385	sporulation resulting in formation of a cellular spore
M1C60_26385	COG4836	Membrane
M1C60_26390	COG1007	ATP synthesis coupled electron transport
M1C60_26395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1C60_26400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1C60_26410	COG0839	Belongs to the complex I subunit 6 family
M1C60_26425	COG0649	NAD binding
M1C60_26430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1C60_26445	COG3300	MHYT domain
M1C60_26445	COG5001	Diguanylate cyclase
M1C60_26495	COG0356	it plays a direct role in the translocation of protons across the membrane
M1C60_26530	COG0698	ribose 5-phosphate isomerase
M1C60_26540	COG2190	(PTS) system
M1C60_26545	COG2259	Doxx family
M1C60_26550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1C60_26565	COG0009	L-threonylcarbamoyladenylate synthase
M1C60_26580	COG2890	protein-(glutamine-N5) methyltransferase activity
M1C60_26600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M1C60_26605	COG1494	fructose-1,6-bisphosphatase
M1C60_26625	COG4821	SIS domain
M1C60_26635	COG3343	RNA polymerase activity
M1C60_26645	COG1960	acyl-CoA dehydrogenase activity
M1C60_26650	COG1960	acyl-CoA dehydrogenase activity
M1C60_26655	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1C60_26660	COG0183	Belongs to the thiolase family
M1C60_26665	COG0247	lactate metabolic process
M1C60_26665	COG2181	nitrate reductase activity
M1C60_26670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_26680	COG5001	Diguanylate cyclase
M1C60_26680	COG3300	MHYT domain
M1C60_26700	COG2197	response regulator
M1C60_26705	COG4585	Histidine kinase
M1C60_26710	COG0842	Transport permease protein
M1C60_26715	COG1131	(ABC) transporter
M1C60_26720	COG0024	Methionine aminopeptidase
M1C60_26730	COG2234	aminopeptidase activity
M1C60_26750	COG1595	DNA-templated transcription, initiation
M1C60_26755	COG0018	arginyl-trna synthetase
M1C60_26760	COG4506	Protein conserved in bacteria
M1C60_26765	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_26780	COG0010	Belongs to the arginase family
M1C60_26790	COG2814	Major facilitator Superfamily
M1C60_26795	COG0789	Transcriptional regulator
M1C60_26800	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_26805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_26815	COG1994	Peptidase M50
M1C60_26825	COG1078	dGTPase activity
M1C60_26830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_26835	COG1120	ATPase activity
M1C60_26840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_26865	COG0095	Lipoate-protein ligase
M1C60_26870	COG0280	phosphate acetyltransferase
M1C60_26885	COG3773	Cell wall hydrolase
M1C60_26895	COG2363	Small membrane protein
M1C60_26905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1C60_26910	COG2233	PERMEase
M1C60_26915	COG0561	phosphatase activity
M1C60_26920	COG2814	Major facilitator Superfamily
M1C60_26930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_26935	COG1131	(ABC) transporter
M1C60_26940	COG2755	lipolytic protein G-D-S-L family
M1C60_26945	COG1609	Transcriptional regulator
M1C60_26955	COG0460	homoserine dehydrogenase
M1C60_26965	COG2873	o-acetylhomoserine
M1C60_26975	COG1011	Hydrolase
M1C60_26980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1C60_26990	COG2197	response regulator
M1C60_27000	COG0351	phosphomethylpyrimidine kinase
M1C60_27005	COG3706	GGDEF domain
M1C60_27010	COG2879	small protein
M1C60_27015	COG1966	Carbon starvation protein
M1C60_27020	COG3279	Response regulator of the LytR AlgR family
M1C60_27025	COG0477	Major facilitator Superfamily
M1C60_27050	COG0840	transmembrane signaling receptor activity
M1C60_27060	COG1607	acyl-coa hydrolase
M1C60_27075	COG0488	(ABC) transporter
M1C60_27095	COG0463	Glycosyl transferase, family 2
M1C60_27100	COG1309	transcriptional regulator
M1C60_27105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1C60_27110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_27110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_27115	COG0628	permease
M1C60_27130	COG3279	Response regulator of the LytR AlgR family
M1C60_27135	COG3275	phosphorelay sensor kinase activity
M1C60_27140	COG2814	Major facilitator Superfamily
M1C60_27145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_27150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M1C60_27155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_27175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1C60_27180	COG1272	protein, Hemolysin III
M1C60_27200	COG0516	GMP reductase activity
M1C60_27205	COG1164	Oligoendopeptidase f
M1C60_27225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_27230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M1C60_27235	COG4853	Protein conserved in bacteria
M1C60_27240	COG4863	YycH protein
M1C60_27245	COG5002	protein histidine kinase activity
M1C60_27250	COG0745	RESPONSE REGULATOR receiver
M1C60_27280	COG0305	Participates in initiation and elongation during chromosome replication
M1C60_27290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M1C60_27295	COG4241	membrane
M1C60_27305	COG0629	single-stranded DNA binding
M1C60_27315	COG0012	GTP binding
M1C60_27320	COG4481	Protein conserved in bacteria
M1C60_27325	COG0668	transmembrane transport
M1C60_27335	COG1475	DNA binding
M1C60_27340	COG1192	Involved in chromosome partitioning
M1C60_27365	COG1847	R3H domain protein
M1C60_27370	COG0706	membrane insertase activity
M1C60_27380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M1C60_27485	COG4962	Type ii secretion system protein e
M1C60_27690	COG3344	reverse transcriptase
M1C60_27770	COG3344	reverse transcriptase
M1C60_27875	COG0457	Tetratricopeptide repeat
M1C60_27900	COG4974	Belongs to the 'phage' integrase family
M1C60_27910	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1C60_27970	COG4974	Belongs to the 'phage' integrase family
M1C60_27980	COG2002	toxin-antitoxin pair type II binding
M1C60_28150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1C60_28155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1C60_28175	COG0671	phosphoesterase, PA-phosphatase related
M1C60_28180	COG4196	transglutaminase domain protein
M1C60_28200	COG2311	Membrane
M1C60_28390	COG0741	lytic transglycosylase activity
M1C60_28390	COG0791	NLP P60 protein
M1C60_28510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_28520	COG4166	transmembrane transport
M1C60_28565	COG1280	lysine exporter protein (LysE YggA)
M1C60_28600	COG0681	Belongs to the peptidase S26 family
M1C60_28675	COG1309	transcriptional regulator
M1C60_28680	COG1683	Conserved Protein
M1C60_28725	COG1192	Involved in chromosome partitioning