locus-tag	class	description
M1D19_00010	COG0592	DNA-directed DNA polymerase activity
M1D19_00015	COG2501	S4 domain
M1D19_00025	COG0187	DNA topoisomerase II activity
M1D19_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1D19_00065	COG0516	GMP reductase activity
M1D19_00065	COG0517	IMP dehydrogenase activity
M1D19_00070	COG1686	Belongs to the peptidase S11 family
M1D19_00100	COG1428	Deoxynucleoside kinase
M1D19_00105	COG1428	Deoxynucleoside kinase
M1D19_00110	COG1335	isochorismatase
M1D19_00115	COG0590	tRNA wobble adenosine to inosine editing
M1D19_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1D19_00180	COG1982	Orn Lys Arg decarboxylase major
M1D19_00190	COG0470	DNA polymerase III
M1D19_00195	COG1774	PSP1 C-terminal conserved region
M1D19_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M1D19_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M1D19_00220	COG2002	toxin-antitoxin pair type II binding
M1D19_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1D19_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1D19_00230	COG0084	hydrolase, TatD family'
M1D19_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1D19_00250	COG4466	Protein conserved in bacteria
M1D19_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M1D19_00270	COG0251	oxidation-reduction process
M1D19_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1D19_00305	COG2002	toxin-antitoxin pair type II binding
M1D19_00310	COG2244	polysaccharide biosynthetic process
M1D19_00315	COG3956	TIGRFAM MazG family protein
M1D19_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1D19_00340	COG1098	S1 RNA binding domain
M1D19_00355	COG2208	phosphoserine phosphatase activity
M1D19_00360	COG0037	tRNA processing
M1D19_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M1D19_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1D19_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1D19_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1D19_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
M1D19_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1D19_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1D19_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M1D19_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1D19_00420	COG1396	sequence-specific DNA binding
M1D19_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1D19_00455	COG3880	PFAM UvrB UvrC protein
M1D19_00465	COG0542	response to heat
M1D19_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M1D19_00480	COG4956	integral membrane protein (PIN domain superfamily)
M1D19_00500	COG1045	serine acetyltransferase
M1D19_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1D19_00520	COG3688	RNA-binding protein containing a PIN domain
M1D19_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1D19_00540	COG0250	Participates in transcription elongation, termination and antitermination
M1D19_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M1D19_00565	COG2813	Specifically methylates the guanine in position
M1D19_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M1D19_00580	COG1358	cellular component organization or biogenesis
M1D19_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
M1D19_00710	COG0201	protein transport
M1D19_00720	COG0024	Methionine aminopeptidase
M1D19_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M1D19_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1D19_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1D19_00795	COG0489	protein tyrosine kinase activity
M1D19_00805	COG2194	sulfuric ester hydrolase activity
M1D19_00810	COG0726	polysaccharide deacetylase
M1D19_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M1D19_00895	COG4856	YbbR-like protein
M1D19_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1D19_00915	COG0596	Alpha beta hydrolase
M1D19_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M1D19_00940	COG0823	Involved in the tonB-independent uptake of proteins
M1D19_00940	COG1506	peptidase
M1D19_00940	COG4946	Tricorn protease homolog
M1D19_00975	COG2011	ABC-type metal ion transport system permease component
M1D19_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1D19_00985	COG1464	Belongs to the NlpA lipoprotein family
M1D19_00990	COG0604	alcohol dehydrogenase
M1D19_01000	COG0277	FAD linked oxidase domain protein
M1D19_01005	COG2271	Major facilitator Superfamily
M1D19_01015	COG2814	Major facilitator Superfamily
M1D19_01030	COG0601	transmembrane transport
M1D19_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1D19_01040	COG0444	Belongs to the ABC transporter superfamily
M1D19_01045	COG4608	Belongs to the ABC transporter superfamily
M1D19_01050	COG4166	transmembrane transport
M1D19_01060	COG2207	Transcriptional regulator
M1D19_01075	COG4166	transmembrane transport
M1D19_01080	COG4166	transmembrane transport
M1D19_01085	COG0656	L-ascorbic acid biosynthetic process
M1D19_01105	COG4149	molybdate abc transporter
M1D19_01115	COG1910	domain protein
M1D19_01125	COG0583	DNA-binding transcription factor activity
M1D19_01130	COG0697	spore germination
M1D19_01145	COG0204	Acyl-transferase
M1D19_01155	COG1609	Transcriptional regulator
M1D19_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_01175	COG0084	hydrolase, TatD family'
M1D19_01180	COG5298	Protein conserved in bacteria
M1D19_01205	COG0488	(ABC) transporter
M1D19_01220	COG0747	negative chemotaxis
M1D19_01225	COG0601	transmembrane transport
M1D19_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1D19_01235	COG0444	Belongs to the ABC transporter superfamily
M1D19_01260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
M1D19_01265	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1D19_01275	COG2814	Major facilitator Superfamily
M1D19_01285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1D19_01295	COG4294	response to UV
M1D19_01300	COG0705	Rhomboid family
M1D19_01300	COG0457	Tetratricopeptide repeat
M1D19_01310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1D19_01315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1D19_01320	COG0864	Transcriptional regulator
M1D19_01325	COG2337	Toxic component of a toxin-antitoxin (TA) module
M1D19_01330	COG2183	response to ionizing radiation
M1D19_01425	COG0802	atpase or kinase
M1D19_01430	COG1214	PFAM Peptidase M22, glycoprotease
M1D19_01435	COG0456	acetyltransferase
M1D19_01445	COG0488	(ABC) transporter
M1D19_01460	COG1266	CAAX protease self-immunity
M1D19_01480	COG2252	PERMEase
M1D19_01490	COG5002	protein histidine kinase activity
M1D19_01520	COG2226	methyltransferase
M1D19_01565	COG1968	undecaprenyl-diphosphatase activity
M1D19_01580	COG2205	protein histidine kinase activity
M1D19_01585	COG0745	RESPONSE REGULATOR receiver
M1D19_01610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M1D19_01615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1D19_01620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1D19_01630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1D19_01645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M1D19_01655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1D19_01665	COG0151	Belongs to the GarS family
M1D19_01690	COG0210	DNA helicase
M1D19_01700	COG4851	CamS sex pheromone cAM373 precursor
M1D19_01720	COG1335	isochorismatase
M1D19_01725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1D19_01730	COG2011	ABC-type metal ion transport system permease component
M1D19_01735	COG1464	Belongs to the NlpA lipoprotein family
M1D19_01760	COG1846	Transcriptional regulator
M1D19_01785	COG1597	lipid kinase activity
M1D19_01790	COG0546	phosphoglycolate phosphatase activity
M1D19_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1D19_01805	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_01810	COG2076	Multidrug Resistance protein
M1D19_01815	COG2309	aminopeptidase activity
M1D19_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1D19_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1D19_01850	COG4807	Protein conserved in bacteria
M1D19_01875	COG1757	Na H antiporter
M1D19_01880	COG1473	amidohydrolase
M1D19_01895	COG0450	alkyl hydroperoxide reductase
M1D19_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_01940	COG0166	Belongs to the GPI family
M1D19_01975	COG5002	protein histidine kinase activity
M1D19_01995	COG3541	Predicted nucleotidyltransferase
M1D19_02000	COG2814	Major facilitator Superfamily
M1D19_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1D19_02005	COG0723	plastoquinol--plastocyanin reductase activity
M1D19_02015	COG0765	amino acid transport
M1D19_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1D19_02030	COG0840	transmembrane signaling receptor activity
M1D19_02035	COG0840	transmembrane signaling receptor activity
M1D19_02040	COG0366	Alpha amylase catalytic
M1D19_02045	COG2190	(PTS) system
M1D19_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_02045	COG1263	PTS System
M1D19_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M1D19_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1D19_02100	COG1116	anion transmembrane transporter activity
M1D19_02105	COG0488	(ABC) transporter
M1D19_02150	COG2270	Major facilitator Superfamily
M1D19_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1D19_02180	COG2310	stress, protein
M1D19_02185	COG2310	stress, protein
M1D19_02190	COG2310	stress, protein
M1D19_02195	COG0861	Integral membrane protein TerC family
M1D19_02205	COG3853	Toxic anion resistance protein (TelA)
M1D19_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1D19_02230	COG1295	ribonuclease BN
M1D19_02235	COG2217	Heavy metal translocating P-type atpase
M1D19_02240	COG0697	spore germination
M1D19_02260	COG0586	Pfam SNARE associated Golgi protein
M1D19_02275	COG3871	stress protein (general stress protein 26)
M1D19_02280	COG0387	Pfam Sodium calcium exchanger
M1D19_02290	COG0535	radical SAM domain protein
M1D19_02315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1D19_02320	COG0582	viral genome integration into host DNA
M1D19_02330	COG1396	sequence-specific DNA binding
M1D19_02345	COG1396	sequence-specific DNA binding
M1D19_02380	COG1484	DNA-dependent DNA replication
M1D19_02610	COG0101	tRNA pseudouridine synthase activity
M1D19_02620	COG3829	transcription factor binding
M1D19_02630	COG0833	amino acid
M1D19_02635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1D19_02665	COG1263	PTS System
M1D19_02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_02670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1D19_02685	COG0463	Glycosyl transferase, family 2
M1D19_02695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1D19_02695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M1D19_02710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M1D19_02730	COG1228	amidohydrolase
M1D19_02735	COG1090	epimerase
M1D19_02765	COG1988	membrane-bound metal-dependent
M1D19_02770	COG1194	a g-specific adenine glycosylase
M1D19_02795	COG1132	(ABC) transporter
M1D19_02800	COG4129	membrane
M1D19_02805	COG0067	glutamate synthase
M1D19_02805	COG0069	glutamate synthase activity
M1D19_02805	COG0070	glutamate synthase
M1D19_02815	COG4555	ABC transporter
M1D19_02835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1D19_02840	COG0735	belongs to the Fur family
M1D19_02955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M1D19_02960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1D19_02970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1D19_02980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1D19_02990	COG2766	serine protein kinase
M1D19_03010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1D19_03020	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1D19_03025	COG2268	Band 7 protein
M1D19_03035	COG3290	protein histidine kinase activity
M1D19_03045	COG2851	Citrate transporter
M1D19_03065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1D19_03070	COG3842	ATPase activity
M1D19_03075	COG1175	transmembrane transport
M1D19_03080	COG0395	ABC-type sugar transport system, permease component
M1D19_03090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1D19_03095	COG0745	RESPONSE REGULATOR receiver
M1D19_03100	COG5002	protein histidine kinase activity
M1D19_03110	COG4990	cell redox homeostasis
M1D19_03120	COG3290	protein histidine kinase activity
M1D19_03125	COG4565	transcriptional regulatory protein
M1D19_03130	COG3493	citrate carrier protein
M1D19_03135	COG0281	malic enzyme
M1D19_03150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_03160	COG5002	protein histidine kinase activity
M1D19_03165	COG0745	RESPONSE REGULATOR receiver
M1D19_03170	COG0456	acetyltransferase
M1D19_03170	COG0454	-acetyltransferase
M1D19_03175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1D19_03180	COG3383	formate dehydrogenase (NAD+) activity
M1D19_03200	COG0531	amino acid
M1D19_03205	COG0640	Transcriptional regulator
M1D19_03210	COG2217	Heavy metal translocating P-type atpase
M1D19_03215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M1D19_03230	COG3227	Zinc metalloprotease (Elastase)
M1D19_03250	COG2720	vancomycin resistance protein
M1D19_03255	COG1316	TRANSCRIPTIONal
M1D19_03260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_03265	COG0346	lactoylglutathione lyase activity
M1D19_03275	COG1027	Aspartate ammonia-lyase
M1D19_03280	COG1620	l-lactate permease
M1D19_03295	COG3104	oligopeptide transport
M1D19_03300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_03320	COG2226	methyltransferase
M1D19_03325	COG0156	8-amino-7-oxononanoate synthase activity
M1D19_03340	COG4548	von Willebrand factor, type A
M1D19_03345	COG0714	Associated with various cellular activities
M1D19_03350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1D19_03370	COG0531	amino acid
M1D19_03375	COG2188	Transcriptional regulator
M1D19_03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_03380	COG1263	PTS System
M1D19_03385	COG0366	Alpha amylase catalytic
M1D19_03400	COG0697	spore germination
M1D19_03410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1D19_03415	COG1115	amino acid carrier protein
M1D19_03420	COG1126	abc transporter atp-binding protein
M1D19_03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1D19_03430	COG0765	amino acid transport
M1D19_03435	COG0765	amino acid transport
M1D19_03440	COG0833	amino acid
M1D19_03465	COG2378	regulation of single-species biofilm formation
M1D19_03470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1D19_03475	COG5002	protein histidine kinase activity
M1D19_03490	COG0659	secondary active sulfate transmembrane transporter activity
M1D19_03505	COG0747	negative chemotaxis
M1D19_03515	COG0601	transmembrane transport
M1D19_03520	COG4608	Belongs to the ABC transporter superfamily
M1D19_03530	COG2271	Major facilitator Superfamily
M1D19_03535	COG1846	Transcriptional regulator
M1D19_03545	COG1609	Transcriptional regulator
M1D19_03550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1D19_03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1D19_03570	COG1879	ABC-type sugar transport system periplasmic component
M1D19_03595	COG1063	alcohol dehydrogenase
M1D19_03610	COG3568	Endonuclease Exonuclease Phosphatase
M1D19_03635	COG1968	undecaprenyl-diphosphatase activity
M1D19_03640	COG0840	transmembrane signaling receptor activity
M1D19_03645	COG3584	3D domain protein
M1D19_03645	COG1388	LysM domain
M1D19_03650	COG1476	TRANSCRIPTIONal
M1D19_03665	COG3104	oligopeptide transport
M1D19_03670	COG1114	Component of the transport system for branched-chain amino acids
M1D19_03685	COG1113	amino acid transport
M1D19_03690	COG2252	PERMEase
M1D19_03715	COG0475	glutathione-regulated potassium exporter activity
M1D19_03715	COG0569	domain protein
M1D19_03730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1D19_03735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1D19_03740	COG4990	cell redox homeostasis
M1D19_03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1D19_03760	COG0697	spore germination
M1D19_03765	COG0531	amino acid
M1D19_03775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1D19_03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1D19_03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1D19_03785	COG1918	ferrous iron import across plasma membrane
M1D19_03790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1D19_03795	COG0573	inorganic phosphate transmembrane transporter activity
M1D19_03800	COG0581	inorganic phosphate transmembrane transporter activity
M1D19_03810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1D19_03925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M1D19_03945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1D19_03950	COG1116	anion transmembrane transporter activity
M1D19_03955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1D19_03960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1D19_03965	COG0352	thiamine-phosphate diphosphorylase activity
M1D19_03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1D19_03975	COG2104	thiamine diphosphate biosynthetic process
M1D19_03985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1D19_03990	COG0351	phosphomethylpyrimidine kinase
M1D19_04030	COG2205	protein histidine kinase activity
M1D19_04035	COG2814	Major facilitator Superfamily
M1D19_04040	COG1846	Transcriptional regulator
M1D19_04055	COG2252	PERMEase
M1D19_04060	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_04075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1D19_04080	COG1621	beta-fructofuranosidase activity
M1D19_04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_04085	COG1263	PTS System
M1D19_04090	COG1609	Transcriptional regulator
M1D19_04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1D19_04105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M1D19_04140	COG0778	Nitroreductase
M1D19_04145	COG2719	SpoVR family
M1D19_04170	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1D19_04175	COG1937	Protein conserved in bacteria
M1D19_04180	COG0425	Belongs to the sulfur carrier protein TusA family
M1D19_04180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1D19_04185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1D19_04190	COG0425	Belongs to the sulfur carrier protein TusA family
M1D19_04205	COG2210	Belongs to the sulfur carrier protein TusA family
M1D19_04210	COG0730	response to heat
M1D19_04220	COG1316	TRANSCRIPTIONal
M1D19_04225	COG0604	alcohol dehydrogenase
M1D19_04230	COG1283	sodium-dependent phosphate transmembrane transporter activity
M1D19_04245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1D19_04245	COG3711	transcriptional antiterminator
M1D19_04250	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1D19_04255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1D19_04275	COG1388	LysM domain
M1D19_04275	COG3584	3D domain protein
M1D19_04280	COG0577	efflux transmembrane transporter activity
M1D19_04285	COG1136	(ABC) transporter
M1D19_04295	COG5522	Integral membrane protein (intg_mem_TP0381)
M1D19_04310	COG1114	Component of the transport system for branched-chain amino acids
M1D19_04315	COG3546	catalase activity
M1D19_04350	COG0586	Pfam SNARE associated Golgi protein
M1D19_04385	COG0531	amino acid
M1D19_04390	COG0475	glutathione-regulated potassium exporter activity
M1D19_04400	COG1737	Transcriptional regulator
M1D19_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_04410	COG1263	PTS System
M1D19_04420	COG2259	Doxx family
M1D19_04435	COG0697	spore germination
M1D19_04440	COG1522	sequence-specific DNA binding
M1D19_04455	COG2076	Multidrug Resistance protein
M1D19_04460	COG1309	transcriptional regulator
M1D19_04465	COG2814	Major facilitator Superfamily
M1D19_04470	COG1733	regulation of RNA biosynthetic process
M1D19_04480	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1D19_04485	COG4533	DNA binding
M1D19_04490	COG2211	Major facilitator Superfamily
M1D19_04500	COG0693	protein deglycase activity
M1D19_04505	COG0753	catalase activity
M1D19_04515	COG0531	amino acid
M1D19_04520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1D19_04530	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_04535	COG1132	(ABC) transporter
M1D19_04545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1D19_04550	COG0765	amino acid transport
M1D19_04555	COG1126	abc transporter atp-binding protein
M1D19_04570	COG0189	ligase activity
M1D19_04600	COG0028	Belongs to the TPP enzyme family
M1D19_04605	COG3527	Alpha-acetolactate decarboxylase
M1D19_04620	COG0561	phosphatase activity
M1D19_04635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1D19_04650	COG0659	secondary active sulfate transmembrane transporter activity
M1D19_04670	COG0653	protein targeting
M1D19_04675	COG2244	polysaccharide biosynthetic process
M1D19_04685	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1D19_04690	COG4196	transglutaminase domain protein
M1D19_04705	COG1696	Membrane protein involved in D-alanine export
M1D19_04720	COG1024	Enoyl-CoA hydratase
M1D19_04740	COG1363	Peptidase, m42
M1D19_04760	COG3938	Belongs to the proline racemase family
M1D19_04800	COG0601	transmembrane transport
M1D19_04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1D19_04815	COG4608	Belongs to the ABC transporter superfamily
M1D19_04850	COG0477	Major facilitator Superfamily
M1D19_04855	COG3290	protein histidine kinase activity
M1D19_04860	COG4565	transcriptional regulatory protein
M1D19_04865	COG3181	Tripartite tricarboxylate transporter family receptor
M1D19_04895	COG0789	Transcriptional regulator
M1D19_04895	COG4978	Transcriptional regulator
M1D19_04910	COG0305	Participates in initiation and elongation during chromosome replication
M1D19_04950	COG0477	Major facilitator Superfamily
M1D19_04995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1D19_04995	COG3320	Male sterility
M1D19_05000	COG1309	transcriptional regulator
M1D19_05020	COG1183	phosphatidylcholine synthase activity
M1D19_05040	COG2376	Dihydroxyacetone kinase
M1D19_05050	COG2376	Dihydroxyacetone kinase
M1D19_05055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1D19_05060	COG1959	2 iron, 2 sulfur cluster binding
M1D19_05090	COG2770	Histidine kinase
M1D19_05090	COG3437	response regulator, receiver
M1D19_05145	COG3237	CsbD-like
M1D19_05170	COG1191	sigma factor activity
M1D19_05180	COG2208	phosphoserine phosphatase activity
M1D19_05185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1D19_05190	COG2198	Histidine kinase
M1D19_05190	COG0784	Response regulator, receiver
M1D19_05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1D19_05190	COG2205	protein histidine kinase activity
M1D19_05245	COG0420	3'-5' exonuclease activity
M1D19_05270	COG1309	transcriptional regulator
M1D19_05275	COG2814	Major facilitator Superfamily
M1D19_05280	COG0346	lactoylglutathione lyase activity
M1D19_05285	COG0346	lactoylglutathione lyase activity
M1D19_05290	COG0457	Tetratricopeptide repeat
M1D19_05295	COG2267	carboxylic ester hydrolase activity
M1D19_05315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1D19_05320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M1D19_05330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M1D19_05370	COG0477	Major facilitator Superfamily
M1D19_05375	COG0477	Major facilitator Superfamily
M1D19_05385	COG3973	AAA domain
M1D19_05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1D19_05410	COG4980	gas vesicle protein
M1D19_05415	COG0537	adenosine 5'-monophosphoramidase activity
M1D19_05420	COG1131	(ABC) transporter
M1D19_05425	COG4473	ABC transporter
M1D19_05440	COG1309	transcriptional regulator
M1D19_05450	COG3402	PFAM membrane-flanked domain
M1D19_05495	COG3402	PFAM membrane-flanked domain
M1D19_05500	COG3428	Bacterial PH domain
M1D19_05505	COG2329	Antibiotic biosynthesis monooxygenase
M1D19_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1D19_05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M1D19_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1D19_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1D19_05560	COG1309	transcriptional regulator
M1D19_05565	COG1511	domain protein
M1D19_05600	COG1234	tRNA 3'-trailer cleavage
M1D19_05605	COG0095	Lipoate-protein ligase
M1D19_05615	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_05645	COG3209	COG3209 Rhs family protein
M1D19_05685	COG1078	dGTPase activity
M1D19_05695	COG1595	DNA-templated transcription, initiation
M1D19_05700	COG2207	Transcriptional regulator
M1D19_05700	COG3708	Transcriptional regulator
M1D19_05715	COG2205	protein histidine kinase activity
M1D19_05720	COG0745	RESPONSE REGULATOR receiver
M1D19_05745	COG0501	Belongs to the peptidase M48B family
M1D19_05750	COG0840	transmembrane signaling receptor activity
M1D19_05755	COG0697	spore germination
M1D19_05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1D19_05780	COG2224	Isocitrate lyase
M1D19_05805	COG4903	ComK protein
M1D19_05810	COG0398	Pfam SNARE associated Golgi protein
M1D19_05820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M1D19_05825	COG1074	ATP-dependent DNA helicase activity
M1D19_05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1D19_05895	COG0367	asparagine synthase
M1D19_05900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1D19_05905	COG0753	catalase activity
M1D19_05910	COG0004	ammonium transporteR
M1D19_05930	COG2996	Protein conserved in bacteria
M1D19_05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1D19_05950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_05965	COG0561	phosphatase activity
M1D19_05975	COG0542	response to heat
M1D19_05985	COG2267	carboxylic ester hydrolase activity
M1D19_06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1D19_06010	COG5504	Zn-dependent protease
M1D19_06020	COG0180	Tryptophanyl-tRNA synthetase
M1D19_06030	COG4166	transmembrane transport
M1D19_06035	COG0601	transmembrane transport
M1D19_06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1D19_06045	COG0444	Belongs to the ABC transporter superfamily
M1D19_06050	COG4608	Belongs to the ABC transporter superfamily
M1D19_06055	COG0534	Mate efflux family protein
M1D19_06060	COG4166	transmembrane transport
M1D19_06075	COG0861	Integral membrane protein TerC family
M1D19_06080	COG4862	establishment of competence for transformation
M1D19_06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1D19_06095	COG1164	Oligoendopeptidase f
M1D19_06105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1D19_06110	COG2346	COG2346, Truncated hemoglobins
M1D19_06115	COG4116	CYTH
M1D19_06125	COG2357	RelA SpoT domain protein
M1D19_06135	COG0564	pseudouridine synthase activity
M1D19_06155	COG0463	Glycosyl transferase, family 2
M1D19_06155	COG1216	Glycosyl transferase, family 2
M1D19_06175	COG0457	Tetratricopeptide repeat
M1D19_06175	COG0463	Glycosyl transferase, family 2
M1D19_06195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M1D19_06210	COG1091	dTDP-4-dehydrorhamnose reductase activity
M1D19_06255	COG2153	protein acetylation
M1D19_06265	COG2382	esterase
M1D19_06280	COG5492	domain, Protein
M1D19_06285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1D19_06295	COG0512	Glutamine amidotransferase of anthranilate synthase
M1D19_06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1D19_06330	COG1620	l-lactate permease
M1D19_06335	COG5634	Uncharacterized conserved protein (DUF2278)
M1D19_06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1D19_06400	COG1476	TRANSCRIPTIONal
M1D19_06460	COG2226	methyltransferase
M1D19_06470	COG1686	Belongs to the peptidase S11 family
M1D19_06475	COG0681	Belongs to the peptidase S26 family
M1D19_06510	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_06515	COG3842	ATPase activity
M1D19_06520	COG1176	ABC-type spermidine putrescine transport system, permease component I
M1D19_06525	COG1177	transmembrane transport
M1D19_06530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M1D19_06540	COG2409	Drug exporters of the RND superfamily
M1D19_06550	COG0564	pseudouridine synthase activity
M1D19_06560	COG2340	Cysteine-rich secretory protein family
M1D19_06565	COG0247	lactate metabolic process
M1D19_06570	COG0277	FAD linked oxidase domain protein
M1D19_06575	COG3835	regulator
M1D19_06585	COG0745	RESPONSE REGULATOR receiver
M1D19_06590	COG5002	protein histidine kinase activity
M1D19_06595	COG2186	Transcriptional regulator
M1D19_06615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1D19_06625	COG2116	formate transmembrane transporter activity
M1D19_06630	COG0861	Integral membrane protein TerC family
M1D19_06635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1D19_06645	COG2030	dehydratase
M1D19_06665	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_06670	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1D19_06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1D19_06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1D19_06695	COG1840	ABC-type Fe3 transport system, periplasmic component
M1D19_06725	COG1349	DNA-binding transcription factor activity
M1D19_06745	COG2861	carbohydrate metabolic process
M1D19_06755	COG3852	Histidine kinase
M1D19_06760	COG1846	Transcriptional regulator
M1D19_06770	COG2318	DinB family
M1D19_06780	COG5002	protein histidine kinase activity
M1D19_06790	COG0720	synthase
M1D19_06805	COG4873	Protein conserved in bacteria
M1D19_06835	COG1780	Probably involved in ribonucleotide reductase function
M1D19_06855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1D19_06860	COG1725	Transcriptional regulator
M1D19_06865	COG1131	(ABC) transporter
M1D19_06875	COG1131	(ABC) transporter
M1D19_06880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1D19_06895	COG1522	sequence-specific DNA binding
M1D19_06905	COG1335	isochorismatase
M1D19_06915	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1D19_06920	COG2070	2-Nitropropane dioxygenase
M1D19_06925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1D19_06935	COG1696	Membrane protein involved in D-alanine export
M1D19_06955	COG0716	FMN binding
M1D19_06970	COG3173	Aminoglycoside phosphotransferase
M1D19_06990	COG0534	Mate efflux family protein
M1D19_06995	COG1968	undecaprenyl-diphosphatase activity
M1D19_07010	COG1846	Transcriptional regulator
M1D19_07020	COG1301	dicarboxylic acid transport
M1D19_07025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1D19_07030	COG4709	membrane
M1D19_07035	COG3874	Sporulation protein YtfJ
M1D19_07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1D19_07065	COG0028	Belongs to the TPP enzyme family
M1D19_07070	COG0440	acetolactate synthase activity
M1D19_07075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1D19_07085	COG0473	3-isopropylmalate dehydrogenase activity
M1D19_07110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1D19_07145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1D19_07160	COG1183	phosphatidylcholine synthase activity
M1D19_07165	COG1368	sulfuric ester hydrolase activity
M1D19_07175	COG0019	diaminopimelate decarboxylase activity
M1D19_07195	COG0529	Catalyzes the synthesis of activated sulfate
M1D19_07200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1D19_07220	COG1648	precorrin-2 dehydrogenase activity
M1D19_07225	COG0733	neurotransmitter:sodium symporter activity
M1D19_07245	COG1757	Na H antiporter
M1D19_07260	COG4758	membrane
M1D19_07265	COG4585	Histidine kinase
M1D19_07270	COG2197	response regulator
M1D19_07280	COG1114	Component of the transport system for branched-chain amino acids
M1D19_07290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1D19_07315	COG1017	nitric oxide dioxygenase activity
M1D19_07315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1D19_07330	COG0730	response to heat
M1D19_07335	COG0306	phosphate transporter
M1D19_07340	COG1392	Phosphate transport regulator
M1D19_07345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1D19_07365	COG1801	Protein of unknown function DUF72
M1D19_07375	COG0582	viral genome integration into host DNA
M1D19_07380	COG5002	protein histidine kinase activity
M1D19_07400	COG0392	lysyltransferase activity
M1D19_07400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M1D19_07415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1D19_07420	COG1686	Belongs to the peptidase S11 family
M1D19_07425	COG2715	membrane protein required for spore maturation
M1D19_07430	COG0700	Nucleoside recognition
M1D19_07435	COG1187	pseudouridine synthase activity
M1D19_07445	COG1333	cytochrome c biogenesis protein
M1D19_07450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1D19_07455	COG0745	RESPONSE REGULATOR receiver
M1D19_07460	COG5002	protein histidine kinase activity
M1D19_07465	COG2096	Adenosyltransferase
M1D19_07480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M1D19_07485	COG1141	Ferredoxin
M1D19_07490	COG4955	Helix-turn-helix domain
M1D19_07495	COG0514	ATP-dependent DNA helicase (RecQ)
M1D19_07500	COG1266	CAAX protease self-immunity
M1D19_07520	COG4862	establishment of competence for transformation
M1D19_07525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1D19_07545	COG0492	ferredoxin-NADP+ reductase activity
M1D19_07550	COG0252	asparaginase activity
M1D19_07620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1D19_07635	COG0142	geranyltranstransferase activity
M1D19_07645	COG0142	geranyltranstransferase activity
M1D19_07665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1D19_07670	COG0457	Tetratricopeptide repeat
M1D19_07690	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M1D19_07700	COG4347	Protein of unknown function (DUF1405)
M1D19_07715	COG2738	Putative neutral zinc metallopeptidase
M1D19_07725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_07730	COG1694	Mazg nucleotide pyrophosphohydrolase
M1D19_07745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1D19_07750	COG0438	transferase activity, transferring glycosyl groups
M1D19_07785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1D19_07785	COG1199	ATP-dependent helicase activity
M1D19_07805	COG3935	DnaD domain protein
M1D19_07810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1D19_07820	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1D19_07820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1D19_07880	COG0116	Belongs to the methyltransferase superfamily
M1D19_07890	COG1199	ATP-dependent helicase activity
M1D19_07895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M1D19_07905	COG3173	Aminoglycoside phosphotransferase
M1D19_07910	COG0024	Methionine aminopeptidase
M1D19_07920	COG2233	PERMEase
M1D19_07925	COG2311	Membrane
M1D19_07930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1D19_07940	COG0456	acetyltransferase
M1D19_07990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1D19_08015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1D19_08030	COG1215	transferase activity, transferring glycosyl groups
M1D19_08035	COG0438	transferase activity, transferring glycosyl groups
M1D19_08050	COG0454	-acetyltransferase
M1D19_08070	COG0328	RNA-DNA hybrid ribonuclease activity
M1D19_08110	COG1280	lysine exporter protein (LysE YggA)
M1D19_08125	COG3162	membrane
M1D19_08130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1D19_08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1D19_08145	COG0475	glutathione-regulated potassium exporter activity
M1D19_08150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1D19_08155	COG0789	Transcriptional regulator
M1D19_08155	COG4978	Transcriptional regulator
M1D19_08165	COG2323	membrane
M1D19_08170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
M1D19_08225	COG1923	regulation of RNA biosynthetic process
M1D19_08235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1D19_08240	COG1360	Flagellar Motor Protein
M1D19_08245	COG2201	protein-glutamate methylesterase activity
M1D19_08255	COG1776	CheC inhibitor of MCP methylation
M1D19_08255	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1D19_08270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1D19_08290	COG1256	bacterial-type flagellum assembly
M1D19_08315	COG1815	bacterial-type flagellum-dependent cell motility
M1D19_08320	COG1558	bacterial-type flagellum-dependent cell motility
M1D19_08335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1D19_08345	COG1157	protein secretion by the type III secretion system
M1D19_08390	COG0463	Glycosyl transferase, family 2
M1D19_08420	COG0463	Glycosyl transferase, family 2
M1D19_08420	COG0457	Tetratricopeptide repeat
M1D19_08435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M1D19_08440	COG0741	lytic transglycosylase activity
M1D19_08455	COG1776	CheC inhibitor of MCP methylation
M1D19_08455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1D19_08465	COG1338	Plays a role in the flagellum-specific transport system
M1D19_08470	COG1987	bacterial-type flagellum assembly
M1D19_08480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1D19_08485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1D19_08495	COG4786	Flagellar basal body rod
M1D19_08500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1D19_08525	COG1309	transcriptional regulator
M1D19_08545	COG2329	Antibiotic biosynthesis monooxygenase
M1D19_08570	COG0583	DNA-binding transcription factor activity
M1D19_08580	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1D19_08590	COG1234	tRNA 3'-trailer cleavage
M1D19_08615	COG1686	Belongs to the peptidase S11 family
M1D19_08625	COG0406	alpha-ribazole phosphatase activity
M1D19_08655	COG0367	asparagine synthase
M1D19_08685	COG1802	Transcriptional regulator
M1D19_08690	COG0697	spore germination
M1D19_08695	COG0523	cobalamin synthesis protein
M1D19_08700	COG0701	Predicted permease
M1D19_08710	COG0438	transferase activity, transferring glycosyl groups
M1D19_08710	COG1216	Glycosyl transferase, family 2
M1D19_08715	COG1757	Na H antiporter
M1D19_08720	COG0114	fumarate hydratase activity
M1D19_08745	COG3340	Belongs to the peptidase S51 family
M1D19_08765	COG0785	Cytochrome C biogenesis protein
M1D19_08795	COG2733	membrane
M1D19_08830	COG1131	(ABC) transporter
M1D19_08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1D19_08850	COG0528	UMP kinase activity
M1D19_08860	COG1027	Aspartate ammonia-lyase
M1D19_08875	COG1063	alcohol dehydrogenase
M1D19_08910	COG1280	lysine exporter protein (LysE YggA)
M1D19_08915	COG3403	YqcI/YcgG family
M1D19_08920	COG5577	PFAM Coat F domain
M1D19_08935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_08940	COG0574	Belongs to the PEP-utilizing enzyme family
M1D19_08940	COG3848	Pyruvate phosphate dikinase
M1D19_08955	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M1D19_08970	COG3314	Sporulation integral membrane protein YlbJ
M1D19_08985	COG1960	acyl-CoA dehydrogenase activity
M1D19_08995	COG0640	Transcriptional regulator
M1D19_09000	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1D19_09015	COG1414	Transcriptional regulator
M1D19_09020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M1D19_09055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1D19_09065	COG0768	penicillin binding
M1D19_09105	COG4335	DNA alkylation repair
M1D19_09115	COG0833	amino acid
M1D19_09125	COG0730	response to heat
M1D19_09155	COG0596	Alpha beta hydrolase
M1D19_09160	COG0745	RESPONSE REGULATOR receiver
M1D19_09165	COG0642	Histidine kinase
M1D19_09185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_09205	COG0456	acetyltransferase
M1D19_09210	COG2207	Transcriptional regulator
M1D19_09235	COG1136	(ABC) transporter
M1D19_09235	COG0577	efflux transmembrane transporter activity
M1D19_09245	COG1725	Transcriptional regulator
M1D19_09280	COG1846	Transcriptional regulator
M1D19_09285	COG0778	Nitroreductase
M1D19_09295	COG0714	Associated with various cellular activities
M1D19_09320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1D19_09330	COG0753	catalase activity
M1D19_09335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1D19_09345	COG0463	Glycosyl transferase, family 2
M1D19_09365	COG0463	Glycosyl transferase, family 2
M1D19_09390	COG0714	Associated with various cellular activities
M1D19_09410	COG0346	lactoylglutathione lyase activity
M1D19_09415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_09425	COG3279	Response regulator of the LytR AlgR family
M1D19_09435	COG4377	Putative membrane peptidase family (DUF2324)
M1D19_09450	COG3655	Transcriptional regulator
M1D19_09460	COG1785	Belongs to the alkaline phosphatase family
M1D19_09470	COG1690	Belongs to the RtcB family
M1D19_09475	COG0833	amino acid
M1D19_09480	COG1414	Transcriptional regulator
M1D19_09485	COG4187	Peptidase family M20/M25/M40
M1D19_09490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1D19_09495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M1D19_09505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_09525	COG2329	Antibiotic biosynthesis monooxygenase
M1D19_09560	COG2390	Transcriptional regulator
M1D19_09570	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1D19_09580	COG1879	ABC-type sugar transport system periplasmic component
M1D19_09605	COG1595	DNA-templated transcription, initiation
M1D19_09615	COG1388	LysM domain
M1D19_09615	COG3584	3D domain protein
M1D19_09650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M1D19_09650	COG1605	Chorismate mutase
M1D19_09655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M1D19_09660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1D19_09665	COG0287	Prephenate dehydrogenase
M1D19_09680	COG1309	transcriptional regulator
M1D19_09695	COG0488	(ABC) transporter
M1D19_09700	COG1368	sulfuric ester hydrolase activity
M1D19_09705	COG0861	Integral membrane protein TerC family
M1D19_09725	COG4912	Dna alkylation repair
M1D19_09745	COG2318	DinB family
M1D19_09750	COG0697	spore germination
M1D19_09775	COG2746	aminoglycoside 3-N-acetyltransferase activity
M1D19_09795	COG2816	NAD+ diphosphatase activity
M1D19_09815	COG1116	anion transmembrane transporter activity
M1D19_09820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1D19_09825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1D19_09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1D19_09845	COG0628	permease
M1D19_09910	COG5146	pantothenate kinase activity
M1D19_09915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M1D19_09920	COG0436	Aminotransferase
M1D19_09955	COG2226	methyltransferase
M1D19_09970	COG2261	transglycosylase associated protein
M1D19_09990	COG2814	Major facilitator Superfamily
M1D19_09990	COG0477	Major facilitator Superfamily
M1D19_09995	COG4533	DNA binding
M1D19_10000	COG0789	Transcriptional regulator
M1D19_10005	COG1664	Polymer-forming cytoskeletal
M1D19_10015	COG2814	Major facilitator Superfamily
M1D19_10035	COG1307	EDD domain protein, DegV family
M1D19_10085	COG5002	protein histidine kinase activity
M1D19_10090	COG2936	dipeptidyl-peptidase activity
M1D19_10135	COG4948	Mandelate Racemase Muconate Lactonizing
M1D19_10145	COG4166	transmembrane transport
M1D19_10150	COG0519	Catalyzes the synthesis of GMP from XMP
M1D19_10155	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1D19_10170	COG0586	Pfam SNARE associated Golgi protein
M1D19_10210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1D19_10215	COG3938	Belongs to the proline racemase family
M1D19_10225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1D19_10230	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_10235	COG1115	amino acid carrier protein
M1D19_10240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1D19_10255	COG3397	chitin binding
M1D19_10280	COG4637	Psort location Cytoplasmic, score
M1D19_10300	COG0514	ATP-dependent DNA helicase (RecQ)
M1D19_10305	COG2105	PFAM AIG2 family protein
M1D19_10320	COG3973	AAA domain
M1D19_10370	COG0658	competence protein
M1D19_10370	COG2333	competence protein COMEC
M1D19_10395	COG2205	protein histidine kinase activity
M1D19_10410	COG3397	chitin binding
M1D19_10415	COG2153	protein acetylation
M1D19_10420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M1D19_10445	COG0517	IMP dehydrogenase activity
M1D19_10445	COG4175	Glycine betaine
M1D19_10450	COG4176	ABC-type proline glycine betaine transport system permease component
M1D19_10480	COG0456	acetyltransferase
M1D19_10480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1D19_10485	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_10495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1D19_10500	COG0022	dehydrogenase e1 component
M1D19_10505	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1D19_10510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1D19_10525	COG1959	2 iron, 2 sulfur cluster binding
M1D19_10545	COG1349	DNA-binding transcription factor activity
M1D19_10565	COG3284	Transcriptional regulator
M1D19_10595	COG1309	transcriptional regulator
M1D19_10600	COG3844	kynureninase activity
M1D19_10605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
M1D19_10610	COG3483	tryptophan 2,3-dioxygenase activity
M1D19_10630	COG2959	enzyme of heme biosynthesis
M1D19_10645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_10650	COG4129	membrane
M1D19_10680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_10685	COG0697	spore germination
M1D19_10695	COG0201	protein transport
M1D19_10715	COG3227	Zinc metalloprotease (Elastase)
M1D19_10720	COG1523	belongs to the glycosyl hydrolase 13 family
M1D19_10735	COG0076	glutamate decarboxylase activity
M1D19_10755	COG1011	Hydrolase
M1D19_10780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1D19_10820	COG0322	excinuclease ABC activity
M1D19_10835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1D19_10885	COG3878	Protein conserved in bacteria
M1D19_10920	COG1051	belongs to the nudix hydrolase family
M1D19_10925	COG0592	DNA-directed DNA polymerase activity
M1D19_10930	COG2816	NAD+ diphosphatase activity
M1D19_10945	COG2223	nitrite transmembrane transporter activity
M1D19_10955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1D19_10985	COG0697	spore germination
M1D19_11005	COG0584	glycerophosphoryl diester phosphodiesterase
M1D19_11020	COG2814	Major facilitator Superfamily
M1D19_11050	COG0693	protein deglycase activity
M1D19_11085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1D19_11095	COG0768	penicillin binding
M1D19_11100	COG0604	alcohol dehydrogenase
M1D19_11105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1D19_11115	COG2205	protein histidine kinase activity
M1D19_11130	COG1122	ATPase activity
M1D19_11140	COG1794	racemase activity, acting on amino acids and derivatives
M1D19_11145	COG1819	glycosyl
M1D19_11150	COG0768	penicillin binding
M1D19_11160	COG0561	phosphatase activity
M1D19_11195	COG2124	cytochrome p450
M1D19_11260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1D19_11270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_11275	COG0460	homoserine dehydrogenase
M1D19_11300	COG1136	(ABC) transporter
M1D19_11330	COG0745	RESPONSE REGULATOR receiver
M1D19_11340	COG3773	Cell wall hydrolase
M1D19_11355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1D19_11360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1D19_11375	COG1063	alcohol dehydrogenase
M1D19_11390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_11410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1D19_11430	COG2814	Major facilitator Superfamily
M1D19_11455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1D19_11455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1D19_11495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1D19_11525	COG2318	DinB family
M1D19_11535	COG0572	uridine kinase
M1D19_11540	COG1247	-acetyltransferase
M1D19_11550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1D19_11555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1D19_11560	COG1024	Enoyl-CoA hydratase
M1D19_11565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1D19_11570	COG0511	ligase activity, forming carbon-carbon bonds
M1D19_11575	COG0439	Biotin carboxylase
M1D19_11580	COG1960	acyl-CoA dehydrogenase activity
M1D19_11595	COG1309	transcriptional regulator
M1D19_11605	COG1131	(ABC) transporter
M1D19_11620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1D19_11625	COG1252	NADH dehydrogenase
M1D19_11640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_11655	COG0488	(ABC) transporter
M1D19_11660	COG1309	transcriptional regulator
M1D19_11680	COG1876	peptidase activity
M1D19_11695	COG1476	TRANSCRIPTIONal
M1D19_11700	COG0457	Tetratricopeptide repeat
M1D19_11725	COG3718	enzyme involved in inositol metabolism
M1D19_11730	COG0191	fructose-bisphosphate aldolase activity
M1D19_11745	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_11755	COG0673	inositol 2-dehydrogenase activity
M1D19_11760	COG2814	Major facilitator Superfamily
M1D19_11765	COG1609	Transcriptional regulator
M1D19_11770	COG0671	phosphoesterase, PA-phosphatase related
M1D19_11775	COG2367	Beta-lactamase
M1D19_11795	COG1595	DNA-templated transcription, initiation
M1D19_11810	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1D19_11850	COG1846	Transcriptional regulator
M1D19_11855	COG3961	Belongs to the TPP enzyme family
M1D19_11860	COG2226	methyltransferase
M1D19_11870	COG3615	Tellurite resistance protein tehB
M1D19_11870	COG0500	methyltransferase
M1D19_11875	COG0577	efflux transmembrane transporter activity
M1D19_11875	COG1136	(ABC) transporter
M1D19_11890	COG1309	transcriptional regulator
M1D19_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_11940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1D19_11945	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1D19_11950	COG2971	BadF BadG BcrA BcrD
M1D19_11975	COG1649	PFAM Uncharacterised BCR, COG1649
M1D19_12000	COG1595	DNA-templated transcription, initiation
M1D19_12005	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
M1D19_12030	COG1396	sequence-specific DNA binding
M1D19_12050	COG1132	(ABC) transporter
M1D19_12055	COG1132	(ABC) transporter
M1D19_12070	COG2258	MOSC domain
M1D19_12075	COG0583	DNA-binding transcription factor activity
M1D19_12090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1D19_12095	COG0583	DNA-binding transcription factor activity
M1D19_12140	COG0561	phosphatase activity
M1D19_12145	COG0010	Belongs to the arginase family
M1D19_12160	COG1278	Cold shock
M1D19_12170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_12180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1D19_12210	COG1247	-acetyltransferase
M1D19_12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_12290	COG2226	methyltransferase
M1D19_12310	COG2814	Major facilitator Superfamily
M1D19_12315	COG0596	Alpha beta hydrolase
M1D19_12330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1D19_12335	COG1187	pseudouridine synthase activity
M1D19_12340	COG2329	Antibiotic biosynthesis monooxygenase
M1D19_12355	COG1115	amino acid carrier protein
M1D19_12365	COG2318	DinB family
M1D19_12375	COG0776	regulation of translation
M1D19_12390	COG2814	Major facilitator Superfamily
M1D19_12395	COG3251	PFAM MbtH domain protein
M1D19_12400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1D19_12405	COG3433	isochorismatase activity
M1D19_12405	COG1535	isochorismatase
M1D19_12410	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1D19_12415	COG1169	isochorismate synthase
M1D19_12420	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_12425	COG2223	nitrite transmembrane transporter activity
M1D19_12450	COG0419	ATPase involved in DNA repair
M1D19_12455	COG0420	3'-5' exonuclease activity
M1D19_12470	COG1024	Enoyl-CoA hydratase
M1D19_12475	COG1280	lysine exporter protein (LysE YggA)
M1D19_12485	COG2084	Dehydrogenase
M1D19_12490	COG1960	acyl-CoA dehydrogenase activity
M1D19_12495	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M1D19_12500	COG2079	MmgE PrpD family protein
M1D19_12505	COG0372	Belongs to the citrate synthase family
M1D19_12510	COG4841	protein insertion into membrane
M1D19_12515	COG2814	Major facilitator Superfamily
M1D19_12525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1D19_12525	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1D19_12565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1D19_12655	COG1715	Restriction endonuclease
M1D19_12655	COG1787	Restriction endonuclease
M1D19_12685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1D19_12690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1D19_12695	COG0671	phosphoesterase, PA-phosphatase related
M1D19_12700	COG4326	sporulation control protein
M1D19_12740	COG1509	lysine 2,3-aminomutase activity
M1D19_12745	COG3829	transcription factor binding
M1D19_12750	COG0456	acetyltransferase
M1D19_12755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1D19_12760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1D19_12765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1D19_12770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1D19_12785	COG5506	Protein of unknown function (DUF1694)
M1D19_12790	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_12795	COG1253	flavin adenine dinucleotide binding
M1D19_12830	COG1174	glycine betaine transport
M1D19_12835	COG1125	glycine betaine transport
M1D19_12835	COG0517	IMP dehydrogenase activity
M1D19_12890	COG1064	alcohol dehydrogenase
M1D19_12900	COG2197	response regulator
M1D19_12905	COG2203	Gaf domain
M1D19_12905	COG4585	Histidine kinase
M1D19_12910	COG0668	transmembrane transport
M1D19_12945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1D19_12950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_12965	COG0367	asparagine synthase
M1D19_12970	COG0071	Belongs to the small heat shock protein (HSP20) family
M1D19_12975	COG1999	signal sequence binding
M1D19_12980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M1D19_12985	COG1307	EDD domain protein, DegV family
M1D19_12995	COG0805	protein transport
M1D19_13005	COG1272	protein, Hemolysin III
M1D19_13010	COG0204	Acyl-transferase
M1D19_13015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1D19_13020	COG0768	penicillin binding
M1D19_13035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1D19_13055	COG0546	phosphoglycolate phosphatase activity
M1D19_13070	COG1131	(ABC) transporter
M1D19_13085	COG0456	acetyltransferase
M1D19_13095	COG1794	racemase activity, acting on amino acids and derivatives
M1D19_13100	COG1454	alcohol dehydrogenase
M1D19_13105	COG2610	gluconate transmembrane transporter activity
M1D19_13130	COG0733	neurotransmitter:sodium symporter activity
M1D19_13145	COG5002	protein histidine kinase activity
M1D19_13145	COG3850	Histidine kinase
M1D19_13150	COG0745	RESPONSE REGULATOR receiver
M1D19_13155	COG0471	metal ion transport
M1D19_13160	COG1929	Belongs to the glycerate kinase type-1 family
M1D19_13230	COG1674	ftsk spoiiie
M1D19_13250	COG0017	Asparaginyl-tRNA synthetase
M1D19_13270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1D19_13295	COG0018	arginyl-trna synthetase
M1D19_13300	COG2521	methyltransferase
M1D19_13300	COG2136	Putative SAM-dependent methyltransferase
M1D19_13315	COG1413	lyase activity
M1D19_13330	COG0629	single-stranded DNA binding
M1D19_13345	COG0488	(ABC) transporter
M1D19_13350	COG1418	mRNA catabolic process
M1D19_13375	COG2359	stage V sporulation protein S
M1D19_13410	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
M1D19_13415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1D19_13420	COG2146	nitrite reductase [NAD(P)H] activity
M1D19_13425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1D19_13425	COG1587	Uroporphyrinogen-III synthase
M1D19_13435	COG1648	precorrin-2 dehydrogenase activity
M1D19_13450	COG2223	nitrite transmembrane transporter activity
M1D19_13460	COG0314	molybdopterin synthase activity
M1D19_13465	COG0303	'Molybdopterin
M1D19_13470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1D19_13475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1D19_13480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1D19_13500	COG2181	nitrate reductase activity
M1D19_13505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M1D19_13510	COG1140	nitrate reductase beta subunit
M1D19_13515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M1D19_13530	COG0714	Associated with various cellular activities
M1D19_13535	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M1D19_13540	COG1305	Transglutaminase-like
M1D19_13545	COG0386	Belongs to the glutathione peroxidase family
M1D19_13570	COG1595	DNA-templated transcription, initiation
M1D19_13575	COG0604	alcohol dehydrogenase
M1D19_13585	COG0346	lactoylglutathione lyase activity
M1D19_13610	COG2226	methyltransferase
M1D19_13635	COG3874	Sporulation protein YtfJ
M1D19_13690	COG0456	acetyltransferase
M1D19_13725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_13730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_13735	COG1819	glycosyl
M1D19_13750	COG4106	trans-aconitate 2-methyltransferase activity
M1D19_13755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1D19_13765	COG0561	phosphatase activity
M1D19_13785	COG2211	Major facilitator Superfamily
M1D19_13790	COG0154	amidase activity
M1D19_13800	COG1876	peptidase activity
M1D19_13810	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1D19_13830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1D19_13835	COG1114	Component of the transport system for branched-chain amino acids
M1D19_13850	COG1253	flavin adenine dinucleotide binding
M1D19_13855	COG2839	Protein conserved in bacteria
M1D19_13860	COG0702	epimerase
M1D19_13885	COG1607	acyl-coa hydrolase
M1D19_13890	COG3689	TIGRFAM TIGR03943 family protein
M1D19_13895	COG0701	Predicted permease
M1D19_13905	COG2244	polysaccharide biosynthetic process
M1D19_13910	COG0586	Pfam SNARE associated Golgi protein
M1D19_13915	COG1051	belongs to the nudix hydrolase family
M1D19_13920	COG5337	Spore coat protein CotH
M1D19_13930	COG0406	alpha-ribazole phosphatase activity
M1D19_13945	COG4166	transmembrane transport
M1D19_13955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1D19_13965	COG0702	epimerase
M1D19_13975	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1D19_13975	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1D19_14035	COG0456	acetyltransferase
M1D19_14040	COG0523	cobalamin synthesis protein
M1D19_14045	COG4989	oxidoreductase activity
M1D19_14055	COG1231	oxidoreductase activity
M1D19_14065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1D19_14080	COG0783	Belongs to the Dps family
M1D19_14085	COG3949	Membrane
M1D19_14100	COG0840	transmembrane signaling receptor activity
M1D19_14125	COG2814	Major facilitator Superfamily
M1D19_14130	COG0667	Aldo Keto reductase
M1D19_14135	COG0640	Transcriptional regulator
M1D19_14140	COG1404	Belongs to the peptidase S8 family
M1D19_14145	COG2002	toxin-antitoxin pair type II binding
M1D19_14185	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1D19_14195	COG1279	arginine transmembrane transporter activity
M1D19_14210	COG1082	Xylose isomerase domain protein TIM barrel
M1D19_14220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1D19_14240	COG1247	-acetyltransferase
M1D19_14245	COG1285	pathogenesis
M1D19_14260	COG5002	protein histidine kinase activity
M1D19_14265	COG0745	RESPONSE REGULATOR receiver
M1D19_14275	COG1316	TRANSCRIPTIONal
M1D19_14300	COG0460	homoserine dehydrogenase
M1D19_14335	COG0300	oxidoreductase activity
M1D19_14345	COG5002	protein histidine kinase activity
M1D19_14350	COG0745	RESPONSE REGULATOR receiver
M1D19_14365	COG1388	LysM domain
M1D19_14365	COG0791	NLP P60 protein
M1D19_14380	COG1686	Belongs to the peptidase S11 family
M1D19_14400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M1D19_14405	COG4988	ABC transporter
M1D19_14410	COG1294	oxidase, subunit
M1D19_14415	COG1271	oxidase subunit
M1D19_14425	COG1846	Transcriptional regulator
M1D19_14435	COG1942	4-Oxalocrotonate Tautomerase
M1D19_14445	COG0583	DNA-binding transcription factor activity
M1D19_14465	COG0411	ABC transporter
M1D19_14475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_14480	COG2030	dehydratase
M1D19_14485	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_14500	COG0523	cobalamin synthesis protein
M1D19_14505	COG1231	oxidoreductase activity
M1D19_14515	COG0628	permease
M1D19_14525	COG0778	Nitroreductase
M1D19_14530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1D19_14535	COG1959	2 iron, 2 sulfur cluster binding
M1D19_14540	COG0583	DNA-binding transcription factor activity
M1D19_14545	COG0697	spore germination
M1D19_14555	COG4549	nuclear export factor GLE1
M1D19_14560	COG2372	response to copper ion
M1D19_14560	COG1276	copper resistance
M1D19_14575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1D19_14590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1D19_14605	COG2132	Multicopper oxidase
M1D19_14610	COG0006	proline dipeptidase activity
M1D19_14630	COG4224	UPF0291 protein
M1D19_14645	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M1D19_14650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_14660	COG2390	Transcriptional regulator
M1D19_14690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1D19_14705	COG1914	H( )-stimulated, divalent metal cation uptake system
M1D19_14725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_14730	COG0535	radical SAM domain protein
M1D19_14760	COG1073	alpha beta
M1D19_14780	COG0427	acetyl-CoA hydrolase
M1D19_14785	COG3279	Response regulator of the LytR AlgR family
M1D19_14795	COG3384	dioxygenase
M1D19_14800	COG2814	Major facilitator Superfamily
M1D19_14825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1D19_14835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1D19_14840	COG0440	acetolactate synthase activity
M1D19_14845	COG0028	Belongs to the TPP enzyme family
M1D19_14850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1D19_14860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1D19_14875	COG2084	Dehydrogenase
M1D19_14895	COG2323	membrane
M1D19_14900	COG5566	PFAM Mor transcription activator
M1D19_14910	COG0733	neurotransmitter:sodium symporter activity
M1D19_14915	COG2244	polysaccharide biosynthetic process
M1D19_14930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1D19_14935	COG2223	nitrite transmembrane transporter activity
M1D19_14945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1D19_14955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_14970	COG1966	Carbon starvation protein
M1D19_14985	COG2814	Major facilitator Superfamily
M1D19_14995	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1D19_15055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1D19_15060	COG0784	Response regulator, receiver
M1D19_15065	COG4191	Histidine kinase
M1D19_15070	COG0281	malic enzyme
M1D19_15075	COG1027	Aspartate ammonia-lyase
M1D19_15080	COG0252	asparaginase activity
M1D19_15085	COG1396	sequence-specific DNA binding
M1D19_15095	COG0322	excinuclease ABC activity
M1D19_15100	COG0531	amino acid
M1D19_15105	COG1114	Component of the transport system for branched-chain amino acids
M1D19_15110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1D19_15120	COG0281	malic enzyme
M1D19_15140	COG0531	amino acid
M1D19_15150	COG0784	Response regulator, receiver
M1D19_15160	COG2066	Belongs to the glutaminase family
M1D19_15195	COG0737	Belongs to the 5'-nucleotidase family
M1D19_15200	COG0753	catalase activity
M1D19_15205	COG2267	carboxylic ester hydrolase activity
M1D19_15210	COG1335	isochorismatase
M1D19_15230	COG0583	DNA-binding transcription factor activity
M1D19_15280	COG0415	Belongs to the DNA photolyase family
M1D19_15285	COG0288	reversible hydration of carbon dioxide
M1D19_15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1D19_15300	COG5609	conserved protein (DUF2294)
M1D19_15315	COG1575	Belongs to the MenA family. Type 1 subfamily
M1D19_15320	COG2267	carboxylic ester hydrolase activity
M1D19_15325	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1D19_15330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1D19_15335	COG1121	(ABC) transporter
M1D19_15365	COG0798	PFAM Bile acid sodium symporter
M1D19_15370	COG0346	lactoylglutathione lyase activity
M1D19_15375	COG0640	Transcriptional regulator
M1D19_15390	COG0443	Heat shock 70 kDa protein
M1D19_15405	COG1522	sequence-specific DNA binding
M1D19_15420	COG0346	lactoylglutathione lyase activity
M1D19_15495	COG2814	Major facilitator Superfamily
M1D19_15520	COG0745	RESPONSE REGULATOR receiver
M1D19_15525	COG3850	Histidine kinase
M1D19_15525	COG5002	protein histidine kinase activity
M1D19_15550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1D19_15570	COG1476	TRANSCRIPTIONal
M1D19_15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_15590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1D19_15600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_15605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M1D19_15620	COG1136	(ABC) transporter
M1D19_15625	COG0577	efflux transmembrane transporter activity
M1D19_15640	COG3850	Histidine kinase
M1D19_15640	COG5002	protein histidine kinase activity
M1D19_15650	COG2364	Membrane
M1D19_15655	COG1846	Transcriptional regulator
M1D19_15665	COG2808	Putative FMN-binding domain
M1D19_15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_15675	COG2271	Major facilitator Superfamily
M1D19_15680	COG1556	Lactate utilization protein
M1D19_15685	COG1139	Iron-sulfur cluster binding protein
M1D19_15695	COG0583	DNA-binding transcription factor activity
M1D19_15705	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1D19_15730	COG0738	Major facilitator superfamily
M1D19_15735	COG0673	inositol 2-dehydrogenase activity
M1D19_15740	COG0561	phosphatase activity
M1D19_15750	COG1609	Transcriptional regulator
M1D19_15755	COG0457	Tetratricopeptide repeat
M1D19_15775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1D19_15805	COG0534	Mate efflux family protein
M1D19_15825	COG2814	Major facilitator Superfamily
M1D19_15830	COG1309	transcriptional regulator
M1D19_15845	COG0814	amino acid
M1D19_15850	COG1760	l-serine dehydratase
M1D19_15855	COG1760	l-serine dehydratase
M1D19_15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1D19_15870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
M1D19_15880	COG1335	isochorismatase
M1D19_15885	COG1522	sequence-specific DNA binding
M1D19_15890	COG0531	amino acid
M1D19_15910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1D19_15930	COG1595	DNA-templated transcription, initiation
M1D19_15945	COG0662	Cupin 2, conserved barrel domain protein
M1D19_15950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_15950	COG2207	Transcriptional regulator
M1D19_16000	COG0477	Major facilitator Superfamily
M1D19_16010	COG1846	Transcriptional regulator
M1D19_16015	COG2814	Major facilitator Superfamily
M1D19_16025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1D19_16030	COG1131	(ABC) transporter
M1D19_16050	COG2076	Multidrug Resistance protein
M1D19_16055	COG1309	transcriptional regulator
M1D19_16065	COG2031	fatty acid transporter
M1D19_16075	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1D19_16105	COG1122	ATPase activity
M1D19_16110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1D19_16125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1D19_16130	COG1288	antiporter activity
M1D19_16135	COG2356	endonuclease I
M1D19_16150	COG3620	sequence-specific DNA binding
M1D19_16155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1D19_16160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1D19_16165	COG0124	histidyl-tRNA synthetase
M1D19_16180	COG1733	regulation of RNA biosynthetic process
M1D19_16185	COG0778	Nitroreductase
M1D19_16205	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_16215	COG1131	(ABC) transporter
M1D19_16240	COG1011	Hydrolase
M1D19_16250	COG2365	Tyrosine phosphatase family
M1D19_16275	COG0346	lactoylglutathione lyase activity
M1D19_16280	COG1940	carbohydrate kinase activity
M1D19_16285	COG0738	Major facilitator superfamily
M1D19_16290	COG0110	maltose O-acetyltransferase activity
M1D19_16300	COG0577	efflux transmembrane transporter activity
M1D19_16300	COG1136	(ABC) transporter
M1D19_16315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M1D19_16320	COG0628	permease
M1D19_16340	COG2226	methyltransferase
M1D19_16350	COG0477	Major facilitator Superfamily
M1D19_16380	COG1253	flavin adenine dinucleotide binding
M1D19_16385	COG0789	Transcriptional regulator
M1D19_16390	COG0697	spore germination
M1D19_16395	COG1357	PFAM Pentapeptide repeats (8 copies)
M1D19_16400	COG3813	Protein conserved in bacteria
M1D19_16405	COG2706	6-phosphogluconolactonase activity
M1D19_16410	COG1070	Carbohydrate kinase
M1D19_16420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1D19_16425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M1D19_16435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1D19_16440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1D19_16445	COG0604	alcohol dehydrogenase
M1D19_16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1D19_16460	COG0604	alcohol dehydrogenase
M1D19_16460	COG3321	synthase
M1D19_16465	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_16490	COG0656	L-ascorbic acid biosynthetic process
M1D19_16495	COG2814	Major facilitator Superfamily
M1D19_16510	COG0346	lactoylglutathione lyase activity
M1D19_16515	COG0814	amino acid
M1D19_16540	COG1393	Belongs to the ArsC family
M1D19_16545	COG1733	regulation of RNA biosynthetic process
M1D19_16550	COG2188	Transcriptional regulator
M1D19_16560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M1D19_16565	COG1733	regulation of RNA biosynthetic process
M1D19_16570	COG1733	regulation of RNA biosynthetic process
M1D19_16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_16605	COG0384	phenazine biosynthesis protein PhzF
M1D19_16615	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_16625	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_16635	COG1733	regulation of RNA biosynthetic process
M1D19_16665	COG1191	sigma factor activity
M1D19_16680	COG1309	transcriptional regulator
M1D19_16700	COG3152	Membrane
M1D19_16725	COG1151	hydroxylamine reductase activity
M1D19_16735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_16740	COG3409	Peptidoglycan-binding domain 1 protein
M1D19_16740	COG3757	hydrolase, family 25
M1D19_16775	COG2072	flavoprotein involved in K transport
M1D19_16815	COG1113	amino acid transport
M1D19_16820	COG2814	Major facilitator Superfamily
M1D19_16850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1D19_16855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1D19_16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_16890	COG3739	integral membrane protein
M1D19_16895	COG0384	phenazine biosynthesis protein PhzF
M1D19_16925	COG0583	DNA-binding transcription factor activity
M1D19_16945	COG1193	negative regulation of DNA recombination
M1D19_16970	COG1164	Oligoendopeptidase f
M1D19_16975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1D19_17005	COG0584	glycerophosphoryl diester phosphodiesterase
M1D19_17030	COG0640	Transcriptional regulator
M1D19_17035	COG0604	alcohol dehydrogenase
M1D19_17055	COG2808	Putative FMN-binding domain
M1D19_17060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1D19_17070	COG0385	Bile acid
M1D19_17075	COG0277	FAD linked oxidase domain protein
M1D19_17105	COG1216	Glycosyl transferase, family 2
M1D19_17110	COG1024	Enoyl-CoA hydratase
M1D19_17120	COG1285	pathogenesis
M1D19_17135	COG2514	catechol 2,3-dioxygenase activity
M1D19_17140	COG2720	vancomycin resistance protein
M1D19_17180	COG0716	FMN binding
M1D19_17210	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_17220	COG0165	Argininosuccinate lyase
M1D19_17235	COG4145	pantothenate transmembrane transporter activity
M1D19_17245	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_17250	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_17260	COG1657	PFAM Prenyltransferase squalene oxidase
M1D19_17265	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M1D19_17270	COG2962	Rard protein
M1D19_17275	COG3326	Membrane
M1D19_17290	COG0489	protein tyrosine kinase activity
M1D19_17300	COG0314	molybdopterin synthase activity
M1D19_17305	COG0303	'Molybdopterin
M1D19_17310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1D19_17315	COG2116	formate transmembrane transporter activity
M1D19_17325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1D19_17330	COG5609	conserved protein (DUF2294)
M1D19_17335	COG2427	Protein of unknown function (DUF1641)
M1D19_17340	COG3383	formate dehydrogenase (NAD+) activity
M1D19_17350	COG0697	spore germination
M1D19_17390	COG2226	methyltransferase
M1D19_17395	COG4166	transmembrane transport
M1D19_17400	COG4166	transmembrane transport
M1D19_17405	COG1301	dicarboxylic acid transport
M1D19_17410	COG1316	TRANSCRIPTIONal
M1D19_17420	COG1595	DNA-templated transcription, initiation
M1D19_17440	COG1131	(ABC) transporter
M1D19_17450	COG0673	inositol 2-dehydrogenase activity
M1D19_17455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1D19_17460	COG0187	DNA topoisomerase II activity
M1D19_17465	COG1832	CoA-binding protein
M1D19_17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1D19_17475	COG0745	RESPONSE REGULATOR receiver
M1D19_17490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1D19_17495	COG4841	protein insertion into membrane
M1D19_17500	COG0824	Thioesterase
M1D19_17530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1D19_17540	COG2274	protein secretion by the type I secretion system
M1D19_17545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1D19_17585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1D19_17600	COG0183	Belongs to the thiolase family
M1D19_17605	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_17610	COG1268	BioY protein
M1D19_17615	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_17665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_17675	COG5002	protein histidine kinase activity
M1D19_17680	COG0400	carboxylic ester hydrolase activity
M1D19_17685	COG0346	lactoylglutathione lyase activity
M1D19_17690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1D19_17695	COG0069	glutamate synthase activity
M1D19_17700	COG1902	pentaerythritol trinitrate reductase activity
M1D19_17705	COG1329	Transcriptional regulator
M1D19_17710	COG0010	Belongs to the arginase family
M1D19_17735	COG2226	methyltransferase
M1D19_17770	COG4846	Membrane protein involved in cytochrome C biogenesis
M1D19_17775	COG0785	Cytochrome C biogenesis protein
M1D19_17785	COG0583	DNA-binding transcription factor activity
M1D19_17790	COG1380	Effector of murein hydrolase LrgA
M1D19_17795	COG1346	cytolysis
M1D19_17820	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1D19_17820	COG3409	Peptidoglycan-binding domain 1 protein
M1D19_17835	COG1132	(ABC) transporter
M1D19_17840	COG1132	(ABC) transporter
M1D19_17870	COG3639	organic phosphonate transmembrane transporter activity
M1D19_17875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
M1D19_17895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1D19_17915	COG1695	Transcriptional regulator
M1D19_17955	COG3409	Peptidoglycan-binding domain 1 protein
M1D19_17955	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1D19_17955	COG1388	LysM domain
M1D19_17960	COG4824	toxin secretion phage lysis holin
M1D19_18115	COG1595	DNA-templated transcription, initiation
M1D19_18160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
M1D19_18245	COG1396	sequence-specific DNA binding
M1D19_18270	COG0174	glutamine synthetase
M1D19_18275	COG0789	Transcriptional regulator
M1D19_18280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M1D19_18290	COG2860	membrane
M1D19_18295	COG0464	growth
M1D19_18325	COG3584	3D domain protein
M1D19_18325	COG1388	LysM domain
M1D19_18330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1D19_18330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1D19_18330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1D19_18335	COG1105	Belongs to the carbohydrate kinase PfkB family
M1D19_18340	COG1349	DNA-binding transcription factor activity
M1D19_18350	COG2322	membrane
M1D19_18360	COG1113	amino acid transport
M1D19_18375	COG1408	metallophosphoesterase
M1D19_18380	COG2116	formate transmembrane transporter activity
M1D19_18390	COG2217	Heavy metal translocating P-type atpase
M1D19_18395	COG2608	mercury ion transmembrane transporter activity
M1D19_18400	COG1937	Protein conserved in bacteria
M1D19_18410	COG2819	hydrolase of the alpha beta superfamily
M1D19_18415	COG1120	ATPase activity
M1D19_18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_18430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_18435	COG0708	Exodeoxyribonuclease III
M1D19_18440	COG2169	Transcriptional regulator
M1D19_18445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1D19_18450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M1D19_18460	COG2364	Membrane
M1D19_18475	COG2267	carboxylic ester hydrolase activity
M1D19_18480	COG0346	lactoylglutathione lyase activity
M1D19_18485	COG3300	MHYT domain
M1D19_18485	COG5001	Diguanylate cyclase
M1D19_18505	COG1346	cytolysis
M1D19_18510	COG1380	Effector of murein hydrolase LrgA
M1D19_18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1D19_18520	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1D19_18520	COG0596	Alpha beta hydrolase
M1D19_18525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1D19_18545	COG1404	Belongs to the peptidase S8 family
M1D19_18550	COG3773	Cell wall hydrolase
M1D19_18555	COG0562	UDP-galactopyranose mutase
M1D19_18560	COG1368	sulfuric ester hydrolase activity
M1D19_18565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1D19_18575	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M1D19_18600	COG1131	(ABC) transporter
M1D19_18620	COG4550	Control of competence regulator ComK, YlbF/YmcA
M1D19_18625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1D19_18630	COG1013	pyruvate-flavodoxin oxidoreductase activity
M1D19_18635	COG0674	pyruvate-flavodoxin oxidoreductase activity
M1D19_18635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M1D19_18645	COG2359	stage V sporulation protein S
M1D19_18650	COG1692	metallophosphoesterase
M1D19_18675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1D19_18680	COG1426	Protein conserved in bacteria
M1D19_18695	COG0300	oxidoreductase activity
M1D19_18700	COG0612	Peptidase, M16
M1D19_18705	COG0612	Peptidase, M16
M1D19_18720	COG3845	ABC transporter
M1D19_18725	COG1744	ABC transporter substrate-binding protein PnrA-like
M1D19_18730	COG2188	Transcriptional regulator
M1D19_18735	COG1674	ftsk spoiiie
M1D19_18745	COG0740	serine-type endopeptidase activity
M1D19_18750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1D19_18760	COG0527	aspartate kinase activity
M1D19_18765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1D19_18770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1D19_18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1D19_18780	COG1873	PFAM PRC-barrel domain
M1D19_18785	COG0612	Peptidase, M16
M1D19_18790	COG0726	polysaccharide deacetylase
M1D19_18805	COG0196	riboflavin kinase activity
M1D19_18810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1D19_18820	COG1550	Protein conserved in bacteria
M1D19_18830	COG1358	cellular component organization or biogenesis
M1D19_18835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M1D19_18840	COG0195	Participates in both transcription termination and antitermination
M1D19_18860	COG0750	zinc metalloprotease
M1D19_18870	COG4589	Belongs to the CDS family
M1D19_18875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1D19_18885	COG0528	UMP kinase activity
M1D19_18915	COG4974	Belongs to the 'phage' integrase family
M1D19_18925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1D19_18935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M1D19_18975	COG1837	Belongs to the UPF0109 family
M1D19_18985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1D19_18995	COG0552	protein localization to endoplasmic reticulum
M1D19_19000	COG1196	nuclear chromosome segregation
M1D19_19010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1D19_19015	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_19020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1D19_19035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1D19_19040	COG1461	Dihydroxyacetone kinase
M1D19_19045	COG1302	Protein conserved in bacteria
M1D19_19060	COG1564	THIamine pyrophosphokinase
M1D19_19065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1D19_19070	COG1162	GTPase activity
M1D19_19075	COG2815	serine threonine protein kinase
M1D19_19075	COG0515	serine threonine protein kinase
M1D19_19080	COG0631	protein serine/threonine phosphatase activity
M1D19_19090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M1D19_19090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M1D19_19100	COG0242	peptide deformylase activity
M1D19_19105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1D19_19110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1D19_19130	COG1561	YicC-like family, N-terminal region
M1D19_19135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1D19_19145	COG0006	proline dipeptidase activity
M1D19_19160	COG3069	C4-dicarboxylate transmembrane transporter activity
M1D19_19225	COG0564	pseudouridine synthase activity
M1D19_19245	COG3599	regulation of cell shape
M1D19_19250	COG2302	S4 RNA-binding domain
M1D19_19255	COG0762	integral membrane protein
M1D19_19265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M1D19_19270	COG1496	oxidoreductase activity
M1D19_19275	COG1873	PFAM PRC-barrel domain
M1D19_19280	COG1191	sigma factor activity
M1D19_19285	COG1191	sigma factor activity
M1D19_19295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1D19_19300	COG0849	cell division
M1D19_19305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1D19_19310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1D19_19320	COG0772	Belongs to the SEDS family
M1D19_19335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1D19_19340	COG0768	penicillin binding
M1D19_19345	COG0768	penicillin binding
M1D19_19350	COG4839	cell division protein FtsL
M1D19_19365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1D19_19380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M1D19_19385	COG1399	metal-binding, possibly nucleic acid-binding protein
M1D19_19435	COG4824	toxin secretion phage lysis holin
M1D19_19535	COG1802	Transcriptional regulator
M1D19_19535	COG4626	Terminase
M1D19_19560	COG0582	viral genome integration into host DNA
M1D19_19625	COG0756	dUTP diphosphatase activity
M1D19_19640	COG1191	sigma factor activity
M1D19_19665	COG1484	DNA-dependent DNA replication
M1D19_19695	COG1396	sequence-specific DNA binding
M1D19_19710	COG1396	sequence-specific DNA binding
M1D19_19725	COG0582	viral genome integration into host DNA
M1D19_19735	COG3480	Lon protease (S16) C-terminal proteolytic domain
M1D19_19740	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1D19_19745	COG3314	Sporulation integral membrane protein YlbJ
M1D19_19755	COG0742	ribosomal rna small subunit methyltransferase
M1D19_19770	COG3679	Belongs to the UPF0342 family
M1D19_19775	COG0406	alpha-ribazole phosphatase activity
M1D19_19790	COG2340	Cysteine-rich secretory protein family
M1D19_19805	COG3336	cytochrome c oxidase
M1D19_19840	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M1D19_19845	COG0772	Belongs to the SEDS family
M1D19_19855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M1D19_19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M1D19_19870	COG4896	Protein conserved in bacteria
M1D19_19885	COG1217	gtp-binding protein TYPA
M1D19_19895	COG0483	inositol monophosphate 1-phosphatase activity
M1D19_19915	COG1982	Orn Lys Arg decarboxylase major
M1D19_19960	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1D19_19965	COG0022	dehydrogenase e1 component
M1D19_19970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1D19_19980	COG0242	peptide deformylase activity
M1D19_19985	COG0561	phosphatase activity
M1D19_19995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1D19_20000	COG0569	domain protein
M1D19_20020	COG0583	DNA-binding transcription factor activity
M1D19_20025	COG0517	IMP dehydrogenase activity
M1D19_20035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M1D19_20045	COG4703	Protein of unknown function (DUF1797)
M1D19_20060	COG2200	EAL domain
M1D19_20065	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_20070	COG1408	metallophosphoesterase
M1D19_20080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M1D19_20115	COG2814	Major facilitator Superfamily
M1D19_20135	COG3209	COG3209 Rhs family protein
M1D19_20145	COG2205	protein histidine kinase activity
M1D19_20155	COG0436	Aminotransferase
M1D19_20160	COG1609	Transcriptional regulator
M1D19_20165	COG3833	ABC-type maltose transport systems, permease component
M1D19_20170	COG1175	transmembrane transport
M1D19_20175	COG2182	Extracellular solute-binding protein
M1D19_20185	COG0366	Alpha amylase catalytic
M1D19_20190	COG3842	ATPase activity
M1D19_20230	COG0183	Belongs to the thiolase family
M1D19_20265	COG1695	Transcriptional regulator
M1D19_20270	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_20280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M1D19_20290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1D19_20295	COG0436	Aminotransferase
M1D19_20315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M1D19_20335	COG2199	diguanylate cyclase activity
M1D19_20340	COG0778	Nitroreductase
M1D19_20365	COG1263	PTS System
M1D19_20365	COG2190	(PTS) system
M1D19_20365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1D19_20370	COG3711	transcriptional antiterminator
M1D19_20380	COG2188	Transcriptional regulator
M1D19_20390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M1D19_20415	COG1547	Domain of unknown function (DUF309)
M1D19_20420	COG0456	acetyltransferase
M1D19_20430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1D19_20435	COG4086	secreted protein
M1D19_20440	COG0561	phosphatase activity
M1D19_20445	COG0697	spore germination
M1D19_20460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_20485	COG0733	neurotransmitter:sodium symporter activity
M1D19_20505	COG1686	Belongs to the peptidase S11 family
M1D19_20510	COG1725	Transcriptional regulator
M1D19_20515	COG1131	(ABC) transporter
M1D19_20530	COG1846	Transcriptional regulator
M1D19_20545	COG0598	Magnesium transport protein CorA
M1D19_20570	COG4974	Belongs to the 'phage' integrase family
M1D19_20580	COG0735	belongs to the Fur family
M1D19_20585	COG1300	Membrane
M1D19_20605	COG0667	Aldo Keto reductase
M1D19_20610	COG0656	L-ascorbic acid biosynthetic process
M1D19_20615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1D19_20615	COG0456	acetyltransferase
M1D19_20625	COG1525	nuclease
M1D19_20625	COG4085	toxin activity
M1D19_20625	COG0737	Belongs to the 5'-nucleotidase family
M1D19_20635	COG0596	Alpha beta hydrolase
M1D19_20640	COG2056	Na+-H+ antiporter family
M1D19_20645	COG1609	Transcriptional regulator
M1D19_20650	COG0456	acetyltransferase
M1D19_20655	COG1073	alpha beta
M1D19_20670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1D19_20670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1D19_20675	COG0307	riboflavin synthase, alpha
M1D19_20700	COG4106	trans-aconitate 2-methyltransferase activity
M1D19_20705	COG2226	methyltransferase
M1D19_20705	COG1073	alpha beta
M1D19_20720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1D19_20730	COG1757	Na H antiporter
M1D19_20735	COG0737	Belongs to the 5'-nucleotidase family
M1D19_20745	COG1522	sequence-specific DNA binding
M1D19_20765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1D19_20775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1D19_20790	COG0300	oxidoreductase activity
M1D19_20800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1D19_20805	COG1760	l-serine dehydratase
M1D19_20810	COG1760	l-serine dehydratase
M1D19_20825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1D19_20835	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1D19_20840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_20855	COG1376	ErfK ybiS ycfS ynhG family protein
M1D19_20860	COG4129	membrane
M1D19_20865	COG1126	abc transporter atp-binding protein
M1D19_20870	COG0765	amino acid transport
M1D19_20875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1D19_20890	COG2816	NAD+ diphosphatase activity
M1D19_20895	COG0772	Belongs to the SEDS family
M1D19_20900	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1D19_20905	COG0022	dehydrogenase e1 component
M1D19_20910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1D19_20915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1D19_20930	COG0280	phosphate acetyltransferase
M1D19_20935	COG3829	transcription factor binding
M1D19_20935	COG3290	protein histidine kinase activity
M1D19_20945	COG0584	glycerophosphoryl diester phosphodiesterase
M1D19_20950	COG3093	addiction module antidote protein HigA
M1D19_20960	COG0745	RESPONSE REGULATOR receiver
M1D19_20965	COG0750	zinc metalloprotease
M1D19_20970	COG0497	DNA recombination
M1D19_20980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M1D19_20990	COG0142	geranyltranstransferase activity
M1D19_21015	COG1302	Protein conserved in bacteria
M1D19_21020	COG0439	Biotin carboxylase
M1D19_21025	COG0511	ligase activity, forming carbon-carbon bonds
M1D19_21070	COG3854	ATPases associated with a variety of cellular activities
M1D19_21095	COG0006	proline dipeptidase activity
M1D19_21110	COG3872	metal-dependent enzyme
M1D19_21120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1D19_21140	COG0095	Lipoate-protein ligase
M1D19_21145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1D19_21150	COG1609	Transcriptional regulator
M1D19_21160	COG2076	Multidrug Resistance protein
M1D19_21165	COG2076	Multidrug Resistance protein
M1D19_21200	COG1131	(ABC) transporter
M1D19_21205	COG1725	Transcriptional regulator
M1D19_21235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1D19_21290	COG4970	Tfp pilus assembly protein FimT
M1D19_21300	COG1459	type II secretion system
M1D19_21305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1D19_21355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M1D19_21360	COG0646	methionine synthase
M1D19_21360	COG1410	methionine synthase
M1D19_21365	COG0646	methionine synthase
M1D19_21365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1D19_21370	COG0626	cystathionine gamma-synthase activity
M1D19_21375	COG0626	cystathionine gamma-synthase activity
M1D19_21395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_21405	COG1940	carbohydrate kinase activity
M1D19_21410	COG4483	Protein conserved in bacteria
M1D19_21415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1D19_21420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M1D19_21425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1D19_21430	COG0704	Plays a role in the regulation of phosphate uptake
M1D19_21440	COG0581	inorganic phosphate transmembrane transporter activity
M1D19_21445	COG0573	inorganic phosphate transmembrane transporter activity
M1D19_21450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1D19_21455	COG0768	penicillin binding
M1D19_21460	COG0477	Major facilitator Superfamily
M1D19_21465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1D19_21490	COG0735	belongs to the Fur family
M1D19_21495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1D19_21500	COG1121	(ABC) transporter
M1D19_21505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_21535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1D19_21540	COG2384	SAM-dependent methyltransferase
M1D19_21545	COG2010	Cytochrome c
M1D19_21550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M1D19_21555	COG0358	DNA primase activity
M1D19_21570	COG0517	IMP dehydrogenase activity
M1D19_21585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1D19_21590	COG0295	cytidine deaminase activity
M1D19_21595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M1D19_21605	COG1480	7TM receptor with intracellular HD hydrolase
M1D19_21610	COG1702	phosphate starvation-inducible protein PhoH
M1D19_21625	COG1610	YqeY-like protein
M1D19_21630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M1D19_21635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1D19_21640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1D19_21670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1D19_21675	COG1733	regulation of RNA biosynthetic process
M1D19_21700	COG1466	dna polymerase III delta subunit
M1D19_21710	COG0658	competence protein
M1D19_21710	COG2333	competence protein COMEC
M1D19_21715	COG2131	deaminase
M1D19_21720	COG1555	photosystem II stabilization
M1D19_21720	COG1596	polysaccharide export
M1D19_21725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1D19_21730	COG2226	methyltransferase
M1D19_21735	COG0799	negative regulation of ribosome biogenesis
M1D19_21740	COG1713	HD superfamily hydrolase involved in NAD metabolism
M1D19_21750	COG1534	Rna-binding protein
M1D19_21760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M1D19_21765	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M1D19_21790	COG1595	DNA-templated transcription, initiation
M1D19_21800	COG0778	Nitroreductase
M1D19_21805	COG2357	RelA SpoT domain protein
M1D19_21815	COG1785	Belongs to the alkaline phosphatase family
M1D19_21825	COG2267	carboxylic ester hydrolase activity
M1D19_21860	COG1404	Belongs to the peptidase S8 family
M1D19_21865	COG3186	Phenylalanine-4-hydroxylase
M1D19_21880	COG2259	Doxx family
M1D19_21920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_21930	COG1012	belongs to the aldehyde dehydrogenase family
M1D19_21930	COG1454	alcohol dehydrogenase
M1D19_21935	COG0626	cystathionine gamma-synthase activity
M1D19_21940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1D19_21965	COG0768	penicillin binding
M1D19_21980	COG0826	peptidase U32
M1D19_21985	COG0826	peptidase U32
M1D19_21990	COG4122	O-methyltransferase activity
M1D19_21995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1D19_22015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1D19_22025	COG0628	permease
M1D19_22045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1D19_22055	COG0482	sulfurtransferase activity
M1D19_22060	COG1104	cysteine desulfurase activity
M1D19_22065	COG1959	2 iron, 2 sulfur cluster binding
M1D19_22070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1D19_22080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1D19_22105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1D19_22115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1D19_22115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M1D19_22120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1D19_22125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1D19_22125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1D19_22135	COG2244	polysaccharide biosynthetic process
M1D19_22140	COG2323	membrane
M1D19_22150	COG1862	Preprotein translocase
M1D19_22180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M1D19_22190	COG0697	spore germination
M1D19_22195	COG0697	spore germination
M1D19_22200	COG0640	Transcriptional regulator
M1D19_22225	COG0157	Belongs to the NadC ModD family
M1D19_22230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M1D19_22235	COG1104	cysteine desulfurase activity
M1D19_22240	COG1827	regulation of RNA biosynthetic process
M1D19_22245	COG2258	MOSC domain
M1D19_22250	COG0077	Prephenate dehydratase
M1D19_22255	COG0577	efflux transmembrane transporter activity
M1D19_22260	COG0577	efflux transmembrane transporter activity
M1D19_22265	COG1136	(ABC) transporter
M1D19_22275	COG0745	RESPONSE REGULATOR receiver
M1D19_22280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M1D19_22285	COG3290	protein histidine kinase activity
M1D19_22295	COG2868	ribosomal protein
M1D19_22305	COG1530	ribonuclease E activity
M1D19_22310	COG1994	Peptidase M50
M1D19_22315	COG0739	heme binding
M1D19_22320	COG2894	cell division
M1D19_22340	COG1077	Cell shape determining protein MreB Mrl
M1D19_22360	COG0285	dihydrofolate synthase activity
M1D19_22365	COG0525	valine-tRNA ligase activity
M1D19_22375	COG1388	LysM domain
M1D19_22385	COG0113	porphobilinogen synthase activity
M1D19_22390	COG1587	Uroporphyrinogen-III synthase
M1D19_22400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1D19_22410	COG1846	Transcriptional regulator
M1D19_22415	COG1764	response to oxidative stress
M1D19_22430	COG0470	DNA polymerase III
M1D19_22430	COG1067	ATP-dependent peptidase activity
M1D19_22475	COG0622	Phosphoesterase
M1D19_22490	COG5401	PFAM Sporulation and spore germination
M1D19_22510	COG1309	transcriptional regulator
M1D19_22525	COG2197	response regulator
M1D19_22530	COG2233	PERMEase
M1D19_22540	COG0402	S-adenosylhomocysteine deaminase activity
M1D19_22545	COG0402	S-adenosylhomocysteine deaminase activity
M1D19_22555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1D19_22565	COG0444	Belongs to the ABC transporter superfamily
M1D19_22570	COG4608	Belongs to the ABC transporter superfamily
M1D19_22575	COG3275	phosphorelay sensor kinase activity
M1D19_22580	COG3279	Response regulator of the LytR AlgR family
M1D19_22595	COG1983	PspC domain protein
M1D19_22600	COG1396	sequence-specific DNA binding
M1D19_22605	COG0697	spore germination
M1D19_22615	COG1959	2 iron, 2 sulfur cluster binding
M1D19_22620	COG1668	transmembrane transport
M1D19_22625	COG4152	abc transporter atp-binding protein
M1D19_22630	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M1D19_22640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1D19_22645	COG1876	peptidase activity
M1D19_22650	COG0824	Thioesterase
M1D19_22655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1D19_22660	COG1053	succinate dehydrogenase
M1D19_22665	COG2009	succinate dehydrogenase
M1D19_22670	COG1719	4-vinyl reductase, 4VR
M1D19_22680	COG3118	belongs to the thioredoxin family
M1D19_22685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M1D19_22690	COG2086	electron transfer activity
M1D19_22695	COG1024	Enoyl-CoA hydratase
M1D19_22705	COG0318	PFAM AMP-dependent synthetase and ligase
M1D19_22725	COG2318	DinB family
M1D19_22755	COG1131	(ABC) transporter
M1D19_22760	COG2205	protein histidine kinase activity
M1D19_22765	COG0745	RESPONSE REGULATOR receiver
M1D19_22775	COG4895	conserved protein (DUF2196)
M1D19_22780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M1D19_22795	COG4509	Sortase family
M1D19_22800	COG1120	ATPase activity
M1D19_22815	COG5386	Cell surface protein
M1D19_22825	COG5386	Cell surface protein
M1D19_22830	COG1114	Component of the transport system for branched-chain amino acids
M1D19_22835	COG1187	pseudouridine synthase activity
M1D19_22845	COG1796	DNA polymerase
M1D19_22845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1D19_22850	COG1286	toxin biosynthetic process
M1D19_22895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1D19_22905	COG1418	mRNA catabolic process
M1D19_22930	COG2814	Major facilitator Superfamily
M1D19_22935	COG1566	PFAM secretion protein HlyD family protein
M1D19_22940	COG1309	transcriptional regulator
M1D19_22945	COG1363	Peptidase, m42
M1D19_22970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1D19_22980	COG1484	DNA-dependent DNA replication
M1D19_22985	COG3611	Membrane attachment protein
M1D19_22995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1D19_23000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1D19_23005	COG0237	dephospho-CoA kinase activity
M1D19_23010	COG1971	Probably functions as a manganese efflux pump
M1D19_23020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1D19_23020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1D19_23025	COG5002	protein histidine kinase activity
M1D19_23030	COG0745	RESPONSE REGULATOR receiver
M1D19_23050	COG0538	isocitrate dehydrogenase activity
M1D19_23055	COG0372	Belongs to the citrate synthase family
M1D19_23065	COG0628	permease
M1D19_23070	COG3030	protein affecting phage T7 exclusion by the F plasmid
M1D19_23095	COG1725	Transcriptional regulator
M1D19_23100	COG0281	malic enzyme
M1D19_23105	COG0587	DNA-directed DNA polymerase activity
M1D19_23120	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M1D19_23140	COG4109	DRTGG domain
M1D19_23155	COG0006	proline dipeptidase activity
M1D19_23195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_23200	COG0662	Cupin 2, conserved barrel domain protein
M1D19_23210	COG1476	TRANSCRIPTIONal
M1D19_23225	COG1028	Short-chain dehydrogenase reductase Sdr
M1D19_23230	COG0589	response to stress
M1D19_23270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_23290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1D19_23295	COG0827	DNA restriction-modification system
M1D19_23300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M1D19_23305	COG3874	Sporulation protein YtfJ
M1D19_23320	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M1D19_23330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1D19_23345	COG1104	cysteine desulfurase activity
M1D19_23355	COG0583	DNA-binding transcription factor activity
M1D19_23360	COG0697	spore germination
M1D19_23370	COG1956	GAF domain-containing protein
M1D19_23375	COG0626	cystathionine gamma-synthase activity
M1D19_23405	COG1595	DNA-templated transcription, initiation
M1D19_23415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1D19_23420	COG0454	-acetyltransferase
M1D19_23425	COG0517	IMP dehydrogenase activity
M1D19_23430	COG0123	including yeast histone deacetylase and acetoin utilization protein
M1D19_23440	COG0745	RESPONSE REGULATOR receiver
M1D19_23450	COG0666	response to abiotic stimulus
M1D19_23485	COG1609	Transcriptional regulator
M1D19_23490	COG4851	CamS sex pheromone cAM373 precursor
M1D19_23495	COG3118	belongs to the thioredoxin family
M1D19_23505	COG2309	aminopeptidase activity
M1D19_23525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_23540	COG1674	ftsk spoiiie
M1D19_23550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1D19_23555	COG4848	Belongs to the UPF0354 family
M1D19_23560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1D19_23565	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
M1D19_23570	COG1363	Peptidase, m42
M1D19_23580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_23595	COG0510	thiamine kinase activity
M1D19_23600	COG1523	belongs to the glycosyl hydrolase 13 family
M1D19_23615	COG1349	DNA-binding transcription factor activity
M1D19_23620	COG1187	pseudouridine synthase activity
M1D19_23625	COG2244	polysaccharide biosynthetic process
M1D19_23630	COG2081	HI0933 family
M1D19_23635	COG2814	Major facilitator Superfamily
M1D19_23645	COG3832	glyoxalase III activity
M1D19_23665	COG1329	Transcriptional regulator
M1D19_23675	COG4975	Glucose uptake
M1D19_23690	COG0314	molybdopterin synthase activity
M1D19_23695	COG1763	Mo-molybdopterin cofactor biosynthetic process
M1D19_23700	COG0303	'Molybdopterin
M1D19_23710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1D19_23735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1D19_23745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1D19_23790	COG2814	Major facilitator Superfamily
M1D19_23795	COG0475	glutathione-regulated potassium exporter activity
M1D19_23800	COG0490	domain, Protein
M1D19_23805	COG0582	viral genome integration into host DNA
M1D19_23815	COG1136	(ABC) transporter
M1D19_23835	COG1242	4 iron, 4 sulfur cluster binding
M1D19_23840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M1D19_23845	COG1131	(ABC) transporter
M1D19_23855	COG1794	racemase activity, acting on amino acids and derivatives
M1D19_23875	COG2267	carboxylic ester hydrolase activity
M1D19_23880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1D19_23885	COG0671	phosphoesterase, PA-phosphatase related
M1D19_23890	COG0438	transferase activity, transferring glycosyl groups
M1D19_23900	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1D19_23955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1D19_23960	COG5002	protein histidine kinase activity
M1D19_23965	COG4191	Histidine kinase
M1D19_23970	COG2267	carboxylic ester hydrolase activity
M1D19_23990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1D19_23995	COG1116	anion transmembrane transporter activity
M1D19_24000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1D19_24025	COG0494	nUDIX hydrolase
M1D19_24060	COG0288	reversible hydration of carbon dioxide
M1D19_24065	COG1271	oxidase subunit
M1D19_24070	COG1294	oxidase, subunit
M1D19_24090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_24115	COG1842	Phage shock protein A
M1D19_24145	COG5002	protein histidine kinase activity
M1D19_24150	COG0745	RESPONSE REGULATOR receiver
M1D19_24180	COG1597	lipid kinase activity
M1D19_24215	COG0586	Pfam SNARE associated Golgi protein
M1D19_24225	COG0577	efflux transmembrane transporter activity
M1D19_24230	COG1136	(ABC) transporter
M1D19_24235	COG2207	Transcriptional regulator
M1D19_24235	COG3708	Transcriptional regulator
M1D19_24240	COG0745	RESPONSE REGULATOR receiver
M1D19_24245	COG2205	protein histidine kinase activity
M1D19_24255	COG0577	efflux transmembrane transporter activity
M1D19_24260	COG1136	(ABC) transporter
M1D19_24280	COG2188	Transcriptional regulator
M1D19_24300	COG3964	amidohydrolase
M1D19_24330	COG4948	Mandelate Racemase Muconate Lactonizing
M1D19_24340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M1D19_24345	COG0596	Alpha beta hydrolase
M1D19_24350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M1D19_24355	COG1169	isochorismate synthase
M1D19_24360	COG1575	Belongs to the MenA family. Type 1 subfamily
M1D19_24365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1D19_24385	COG0058	SHG alpha-glucan phosphorylase activity
M1D19_24390	COG0297	glycogen (starch) synthase activity
M1D19_24395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M1D19_24510	COG0544	peptidyl-prolyl cis-trans isomerase activity
M1D19_24545	COG1285	pathogenesis
M1D19_24550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1D19_24560	COG0166	Belongs to the GPI family
M1D19_24565	COG2155	Conserved Protein
M1D19_24570	COG1098	S1 RNA binding domain
M1D19_24575	COG0436	Aminotransferase
M1D19_24580	COG1522	sequence-specific DNA binding
M1D19_24585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1D19_24590	COG2267	carboxylic ester hydrolase activity
M1D19_24600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M1D19_24620	COG5018	Exonuclease
M1D19_24625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1D19_24645	COG2050	protein possibly involved in aromatic compounds catabolism
M1D19_24655	COG1268	BioY protein
M1D19_24665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1D19_24670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1D19_24685	COG3584	3D domain protein
M1D19_24700	COG1252	NADH dehydrogenase
M1D19_24715	COG3708	Transcriptional regulator
M1D19_24730	COG1683	Conserved Protein
M1D19_24750	COG0316	Belongs to the HesB IscA family
M1D19_24765	COG1252	NADH dehydrogenase
M1D19_24780	COG0390	transport system, permease component
M1D19_24785	COG2824	Alkylphosphonate utilization operon protein PhnA
M1D19_24825	COG4837	Protein of unknown function (DUF1462)
M1D19_24830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M1D19_24840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1D19_24845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1D19_24855	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1D19_24860	COG0647	UMP catabolic process
M1D19_24870	COG2445	Protein of unknown function DUF86
M1D19_24875	COG1494	fructose-1,6-bisphosphatase
M1D19_24890	COG4470	Protein conserved in bacteria
M1D19_24900	COG0789	Transcriptional regulator
M1D19_24905	COG4377	Putative membrane peptidase family (DUF2324)
M1D19_24930	COG0739	heme binding
M1D19_24940	COG3377	Domain of unknown function (DUF1805)
M1D19_24945	COG0737	Belongs to the 5'-nucleotidase family
M1D19_24950	COG1695	Transcriptional regulator
M1D19_24960	COG0719	Fe-S assembly protein
M1D19_24965	COG0822	iron-sulfur transferase activity
M1D19_24970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1D19_24975	COG0719	Fe-S assembly protein
M1D19_24980	COG0396	ATPase activity
M1D19_24985	COG1464	Belongs to the NlpA lipoprotein family
M1D19_24990	COG1464	Belongs to the NlpA lipoprotein family
M1D19_24995	COG2011	ABC-type metal ion transport system permease component
M1D19_25000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1D19_25010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1D19_25015	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1D19_25025	COG1393	Belongs to the ArsC family
M1D19_25070	COG0039	L-malate dehydrogenase activity
M1D19_25095	COG1309	transcriptional regulator
M1D19_25100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1D19_25105	COG1960	acyl-CoA dehydrogenase activity
M1D19_25110	COG0183	Belongs to the thiolase family
M1D19_25115	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1D19_25115	COG1024	Enoyl-CoA hydratase
M1D19_25125	COG1686	Belongs to the peptidase S11 family
M1D19_25140	COG0011	TIGRFAM Protein of
M1D19_25145	COG0840	transmembrane signaling receptor activity
M1D19_25165	COG2814	Major facilitator Superfamily
M1D19_25170	COG0531	amino acid
M1D19_25180	COG0706	membrane insertase activity
M1D19_25190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1D19_25225	COG0586	Pfam SNARE associated Golgi protein
M1D19_25235	COG1376	ErfK ybiS ycfS ynhG family protein
M1D19_25240	COG0745	RESPONSE REGULATOR receiver
M1D19_25245	COG5002	protein histidine kinase activity
M1D19_25270	COG2151	metal-sulfur cluster biosynthetic enzyme
M1D19_25275	COG3227	Zinc metalloprotease (Elastase)
M1D19_25280	COG1741	Belongs to the pirin family
M1D19_25295	COG0475	glutathione-regulated potassium exporter activity
M1D19_25300	COG0490	domain, Protein
M1D19_25305	COG1115	amino acid carrier protein
M1D19_25310	COG0783	Belongs to the Dps family
M1D19_25325	COG1611	Belongs to the LOG family
M1D19_25345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_25350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_25355	COG1115	amino acid carrier protein
M1D19_25360	COG1115	amino acid carrier protein
M1D19_25365	COG2910	NAD(P)H-binding
M1D19_25380	COG0656	L-ascorbic acid biosynthetic process
M1D19_25385	COG2814	Major facilitator Superfamily
M1D19_25390	COG1733	regulation of RNA biosynthetic process
M1D19_25400	COG1252	NADH dehydrogenase
M1D19_25405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1D19_25410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1D19_25420	COG0840	transmembrane signaling receptor activity
M1D19_25420	COG3290	protein histidine kinase activity
M1D19_25430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1D19_25435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1D19_25450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1D19_25505	COG0557	exoribonuclease II activity
M1D19_25510	COG1647	Serine aminopeptidase, S33
M1D19_25515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1D19_25520	COG1346	cytolysis
M1D19_25625	COG4695	Portal protein
M1D19_25650	COG4974	Belongs to the 'phage' integrase family
M1D19_25660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1D19_25665	COG0149	triose-phosphate isomerase activity
M1D19_25675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1D19_25690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M1D19_25715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1D19_25730	COG2323	membrane
M1D19_25735	COG0740	serine-type endopeptidase activity
M1D19_25740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1D19_25750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M1D19_25760	COG1051	belongs to the nudix hydrolase family
M1D19_25770	COG0492	ferredoxin-NADP+ reductase activity
M1D19_25775	COG0457	Tetratricopeptide repeat
M1D19_25780	COG0110	maltose O-acetyltransferase activity
M1D19_25800	COG1950	PFAM Membrane protein of
M1D19_25810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1D19_25815	COG0556	nucleotide-excision repair
M1D19_25835	COG0789	Transcriptional regulator
M1D19_25860	COG2855	membrane
M1D19_25865	COG0583	DNA-binding transcription factor activity
M1D19_25875	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1D19_25880	COG0488	(ABC) transporter
M1D19_25890	COG1132	(ABC) transporter
M1D19_25895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1D19_25900	COG0793	Belongs to the peptidase S41A family
M1D19_25900	COG3409	Peptidoglycan-binding domain 1 protein
M1D19_25905	COG2177	Part of the ABC transporter FtsEX involved in
M1D19_25910	COG2884	Cell division ATP-binding protein ftsE
M1D19_25925	COG0653	protein targeting
M1D19_25930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M1D19_25935	COG1278	Cold shock
M1D19_25940	COG1040	competence protein
M1D19_25945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M1D19_25950	COG0791	NLP P60 protein
M1D19_25950	COG1388	LysM domain
M1D19_25955	COG1733	regulation of RNA biosynthetic process
M1D19_25960	COG1307	EDD domain protein, DegV family
M1D19_25965	COG1739	Uncharacterized protein family UPF0029
M1D19_25970	COG1316	TRANSCRIPTIONal
M1D19_25975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1D19_25980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1D19_25985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M1D19_25995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M1D19_25995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M1D19_26010	COG3394	polysaccharide catabolic process
M1D19_26015	COG1486	melibiose metabolic process
M1D19_26020	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1D19_26025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1D19_26035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M1D19_26040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1D19_26045	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1D19_26055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1D19_26060	COG1301	dicarboxylic acid transport
M1D19_26070	COG0346	lactoylglutathione lyase activity
M1D19_26075	COG1511	domain protein
M1D19_26080	COG0583	DNA-binding transcription factor activity
M1D19_26085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M1D19_26100	COG1271	oxidase subunit
M1D19_26105	COG1294	oxidase, subunit
M1D19_26110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1D19_26120	COG1620	l-lactate permease
M1D19_26130	COG2389	metal-binding protein
M1D19_26140	COG1368	sulfuric ester hydrolase activity
M1D19_26155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1D19_26170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1D19_26175	COG1388	LysM domain
M1D19_26175	COG3584	3D domain protein
M1D19_26200	COG4715	Zinc finger, swim domain protein
M1D19_26205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1D19_26245	COG0577	efflux transmembrane transporter activity
M1D19_26250	COG1136	(ABC) transporter
M1D19_26285	COG5002	protein histidine kinase activity
M1D19_26290	COG0745	RESPONSE REGULATOR receiver
M1D19_26295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1D19_26315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1D19_26320	COG1134	teichoic acid transport
M1D19_26325	COG1682	transport, permease protein
M1D19_26330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1D19_26375	COG1609	Transcriptional regulator
M1D19_26390	COG0739	heme binding
M1D19_26410	COG2385	sporulation resulting in formation of a cellular spore
M1D19_26425	COG4836	Membrane
M1D19_26430	COG1007	ATP synthesis coupled electron transport
M1D19_26435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1D19_26440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1D19_26450	COG0839	Belongs to the complex I subunit 6 family
M1D19_26465	COG0649	NAD binding
M1D19_26470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1D19_26485	COG5001	Diguanylate cyclase
M1D19_26485	COG3300	MHYT domain
M1D19_26535	COG0356	it plays a direct role in the translocation of protons across the membrane
M1D19_26570	COG0698	ribose 5-phosphate isomerase
M1D19_26580	COG2190	(PTS) system
M1D19_26585	COG2259	Doxx family
M1D19_26590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1D19_26605	COG0009	L-threonylcarbamoyladenylate synthase
M1D19_26620	COG2890	protein-(glutamine-N5) methyltransferase activity
M1D19_26640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M1D19_26645	COG1494	fructose-1,6-bisphosphatase
M1D19_26665	COG4821	SIS domain
M1D19_26675	COG3343	RNA polymerase activity
M1D19_26685	COG1960	acyl-CoA dehydrogenase activity
M1D19_26690	COG1960	acyl-CoA dehydrogenase activity
M1D19_26695	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1D19_26700	COG0183	Belongs to the thiolase family
M1D19_26705	COG0247	lactate metabolic process
M1D19_26705	COG2181	nitrate reductase activity
M1D19_26710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1D19_26720	COG5001	Diguanylate cyclase
M1D19_26720	COG3300	MHYT domain
M1D19_26740	COG2197	response regulator
M1D19_26745	COG4585	Histidine kinase
M1D19_26750	COG0842	Transport permease protein
M1D19_26755	COG1131	(ABC) transporter
M1D19_26760	COG0024	Methionine aminopeptidase
M1D19_26770	COG2234	aminopeptidase activity
M1D19_26790	COG1595	DNA-templated transcription, initiation
M1D19_26795	COG0018	arginyl-trna synthetase
M1D19_26800	COG4506	Protein conserved in bacteria
M1D19_26805	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1D19_26820	COG0010	Belongs to the arginase family
M1D19_26830	COG2814	Major facilitator Superfamily
M1D19_26835	COG0789	Transcriptional regulator
M1D19_26840	COG0584	glycerophosphoryl diester phosphodiesterase
M1D19_26845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1D19_26855	COG1994	Peptidase M50
M1D19_26865	COG1078	dGTPase activity
M1D19_26870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1D19_26875	COG1120	ATPase activity
M1D19_26880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1D19_26905	COG0095	Lipoate-protein ligase
M1D19_26910	COG0280	phosphate acetyltransferase
M1D19_26925	COG3773	Cell wall hydrolase
M1D19_26935	COG2363	Small membrane protein
M1D19_26950	COG2233	PERMEase
M1D19_26955	COG0561	phosphatase activity
M1D19_26960	COG2814	Major facilitator Superfamily
M1D19_26970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1D19_26975	COG1131	(ABC) transporter
M1D19_26980	COG2755	lipolytic protein G-D-S-L family
M1D19_26985	COG1609	Transcriptional regulator
M1D19_26995	COG0460	homoserine dehydrogenase
M1D19_27005	COG2873	o-acetylhomoserine
M1D19_27015	COG1011	Hydrolase
M1D19_27020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1D19_27030	COG2197	response regulator
M1D19_27040	COG0351	phosphomethylpyrimidine kinase
M1D19_27045	COG3706	GGDEF domain
M1D19_27050	COG2879	small protein
M1D19_27055	COG1966	Carbon starvation protein
M1D19_27060	COG3279	Response regulator of the LytR AlgR family
M1D19_27065	COG0477	Major facilitator Superfamily
M1D19_27090	COG0840	transmembrane signaling receptor activity
M1D19_27100	COG1607	acyl-coa hydrolase
M1D19_27115	COG0488	(ABC) transporter
M1D19_27135	COG0463	Glycosyl transferase, family 2
M1D19_27140	COG1309	transcriptional regulator
M1D19_27145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1D19_27150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1D19_27150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1D19_27155	COG0628	permease
M1D19_27170	COG3279	Response regulator of the LytR AlgR family
M1D19_27175	COG3275	phosphorelay sensor kinase activity
M1D19_27180	COG2814	Major facilitator Superfamily
M1D19_27185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1D19_27190	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M1D19_27195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1D19_27215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1D19_27220	COG1272	protein, Hemolysin III
M1D19_27240	COG0516	GMP reductase activity
M1D19_27245	COG1164	Oligoendopeptidase f
M1D19_27265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1D19_27270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M1D19_27275	COG4853	Protein conserved in bacteria
M1D19_27280	COG4863	YycH protein
M1D19_27285	COG5002	protein histidine kinase activity
M1D19_27290	COG0745	RESPONSE REGULATOR receiver
M1D19_27320	COG0305	Participates in initiation and elongation during chromosome replication
M1D19_27330	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M1D19_27335	COG4241	membrane
M1D19_27345	COG0629	single-stranded DNA binding
M1D19_27355	COG0012	GTP binding
M1D19_27360	COG4481	Protein conserved in bacteria
M1D19_27365	COG0668	transmembrane transport
M1D19_27375	COG1475	DNA binding
M1D19_27380	COG1192	Involved in chromosome partitioning
M1D19_27405	COG1847	R3H domain protein
M1D19_27410	COG0706	membrane insertase activity
M1D19_27420	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M1D19_27525	COG4962	Type ii secretion system protein e
M1D19_27730	COG3344	reverse transcriptase
M1D19_27810	COG3344	reverse transcriptase
M1D19_27915	COG0457	Tetratricopeptide repeat
M1D19_27940	COG4974	Belongs to the 'phage' integrase family
M1D19_27950	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1D19_28015	COG4974	Belongs to the 'phage' integrase family
M1D19_28025	COG2002	toxin-antitoxin pair type II binding
M1D19_28200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1D19_28205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1D19_28225	COG0671	phosphoesterase, PA-phosphatase related
M1D19_28230	COG4196	transglutaminase domain protein
M1D19_28255	COG2311	Membrane