locus-tag class description BAZ_00002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAZ_00003 ENOG410848D S4 domain protein YaaA BAZ_00006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAZ_00013 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAZ_00020 ENOG4105ZMH deoxynucleoside kinase BAZ_00022 ENOG4105GTG Isochorismatase BAZ_00023 ENOG4108Z6B deaminase BAZ_00024 ENOG4105C6E dna polymerase iii BAZ_00028 ENOG41067KS pro-sigma K processing BAZ_00035 ENOG4105CXN decarboxylase BAZ_00037 ENOG4105FA2 dna polymerase iii BAZ_00038 ENOG4105MA4 psp1 domain protein BAZ_00040 ENOG41060K3 Methyltransferase BAZ_00042 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAZ_00043 ENOG4105KRN Transcriptional regulator, abrb family BAZ_00045 ENOG4105F8V Hydrolase, tatD family BAZ_00046 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BAZ_00048 ENOG4105XFA sporulation peptidase YabG BAZ_00049 ENOG4105W42 Veg protein BAZ_00052 ENOG4105DFT pur operon repressor BAZ_00053 ENOG4105KME endoribonuclease L-psp BAZ_00056 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAZ_00057 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BAZ_00059 ENOG4108JA2 transcriptioN-repair coupling factor BAZ_00060 ENOG4108M14 stage v sporulation protein t BAZ_00062 ENOG4108IY2 MazG family BAZ_00063 ENOG41082I2 s4 domain protein BAZ_00064 ENOG4105VYY sporulation protein yabp BAZ_00067 ENOG41060GV RNA binding s1 domain protein BAZ_00071 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAZ_00072 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAZ_00073 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAZ_00076 ENOG4105C6T cysteine synthase BAZ_00077 ENOG4105CRQ synthase (Component I) BAZ_00078 ENOG4105DDQ anthranilate synthase BAZ_00079 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAZ_00080 ENOG4105EEI dihydropteroate synthase BAZ_00081 ENOG4105KRF dihydroneopterin aldolase BAZ_00082 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAZ_00084 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAZ_00090 ENOG4108Z0C Uvrb UvrC protein BAZ_00093 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAZ_00095 ENOG4105CTP PilT protein domain protein BAZ_00099 ENOG4105D7W serine acetyltransferase BAZ_00102 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAZ_00103 ENOG4105M0M Tetracycline resistance protein BAZ_00104 ENOG4105QIV RNA polymerase BAZ_00106 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAZ_00111 ENOG4107Y49 methyltransferase BAZ_00113 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAZ_00114 ENOG4105XPM ribosomal protein BAZ_00135 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAZ_00140 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAZ_00142 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAZ_00144 ENOG41067V7 50S ribosomal protein L36 BAZ_00150 ENOG4108JJB ABC transporter BAZ_00151 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAZ_00152 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAZ_00157 ENOG4105D1F ATP-binding protein BAZ_00160 ENOG4108NMV polysaccharide deacetylase BAZ_00177 ENOG4105C8B TIGR00159 family BAZ_00178 ENOG4107U5W ybbr family BAZ_00180 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BAZ_00181 ENOG4108VQT Alpha beta hydrolase fold protein BAZ_00183 ENOG4105CMG Carbohydrate kinase BAZ_00184 ENOG4105CMG Carbohydrate kinase BAZ_00186 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAZ_00187 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAZ_00195 ENOG4108PSK reductase BAZ_00196 ENOG4108UMI ABC transporter, permease BAZ_00197 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAZ_00198 ENOG4105D01 (LipO)protein BAZ_00199 ENOG4105EE1 crotonyl-CoA reductase BAZ_00201 ENOG4105IQ5 FAD linked oxidase domain protein BAZ_00204 ENOG4105C2C drug resistance transporter, Bcr CflA BAZ_00207 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAZ_00208 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAZ_00209 ENOG4105C3U ABC transporter BAZ_00210 ENOG4108JQ7 (ABC) transporter BAZ_00216 ENOG4108J59 Extracellular solute-binding protein, family 5 BAZ_00217 ENOG4108J59 Extracellular solute-binding protein, family 5 BAZ_00219 ENOG4105II7 pyrroline-5-carboxylate reductase BAZ_00220 ENOG4107XDY Nicotinamide Mononucleotide Transporter BAZ_00222 ENOG4105E0C molybdate abc transporter BAZ_00223 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAZ_00224 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAZ_00225 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAZ_00228 ENOG4105EGI Transcriptional regulator BAZ_00232 ENOG4105F6E Acyl-transferase BAZ_00236 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAZ_00239 ENOG4108RE7 deoxyribonuclease BAZ_00240 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAZ_00244 ENOG4105C5H ABC transporter BAZ_00247 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BAZ_00249 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAZ_00250 ENOG4105C3U ABC transporter BAZ_00251 ENOG4108JQ7 (ABC) transporter BAZ_00252 ENOG410667J hydrolase BAZ_00259 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BAZ_00260 ENOG4105ERH Fumarylacetoacetate hydrolase BAZ_00262 ENOG4108SC4 )-transporter BAZ_00263 ENOG4105CPF Cell wall formation (By similarity) BAZ_00264 ENOG4105CPF Cell wall formation (By similarity) BAZ_00265 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAZ_00268 ENOG4107ZXI Rhomboid family BAZ_00270 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAZ_00271 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAZ_00273 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAZ_00292 ENOG4105K8N protein family UPF0079, ATPase BAZ_00293 ENOG41072GX Peptidase M22 Glycoprotease BAZ_00294 ENOG410801F ribosomal-protein-alanine acetyltransferase BAZ_00295 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAZ_00296 ENOG4105C5H ABC transporter BAZ_00299 ENOG4108TYN CAAX amino terminal protease family protein BAZ_00303 ENOG4105C7N Xanthine uracil vitamin C permease BAZ_00305 ENOG4105BZU Histidine kinase BAZ_00311 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAZ_00316 ENOG4108SHN Glycosyl transferase, family 2 BAZ_00320 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAZ_00321 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAZ_00322 ENOG4105C83 adenylosuccinate lyase BAZ_00324 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAZ_00329 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAZ_00331 ENOG4105C12 Phosphoribosylglycinamide synthetase BAZ_00336 ENOG4105C4R Atp-dependent dna helicase BAZ_00342 ENOG4108W2Y isochorismatase BAZ_00343 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAZ_00344 ENOG4108UMI ABC transporter, permease BAZ_00345 ENOG4105D01 (LipO)protein BAZ_00349 ENOG4105D0U Arsenite-activated ATPase (ArsA) BAZ_00350 ENOG410834F Transcriptional regulator BAZ_00351 ENOG4107I77 yiaA/B two helix domain BAZ_00355 ENOG4105CBD Diacylglycerol kinase BAZ_00356 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAZ_00357 ENOG4108JPW Aminotransferase BAZ_00359 ENOG4105C26 Dehydrogenase BAZ_00360 ENOG4105KPY Small multidrug resistance protein BAZ_00364 ENOG4105D9N nucleoside BAZ_00365 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAZ_00368 ENOG4108W15 Protein of unknown function (DUF1456) BAZ_00371 ENOG4105DTQ mandelate racemase muconate lactonizing BAZ_00373 ENOG4105DFD Na H antiporter BAZ_00377 ENOG4105D3R alkyl hydroperoxide reductase BAZ_00378 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BAZ_00380 ENOG4107W7X Aldolase BAZ_00381 ENOG4105EHG Permease protein BAZ_00382 ENOG4105DQ5 transport system permease protein BAZ_00383 ENOG4108V5C ABC transporter BAZ_00387 ENOG4106UIA BAZ_00388 ENOG4106UIA BAZ_00392 ENOG4105BZU Histidine kinase BAZ_00396 ENOG410756H nucleotidyltransferase BAZ_00397 ENOG4105D2S major facilitator superfamily BAZ_00400 ENOG4105E5Q amino acid AbC transporter BAZ_00401 ENOG4105EAB amino acid AbC transporter BAZ_00403 ENOG4105C8Q Methyl-accepting chemotaxis BAZ_00404 ENOG4105C8Q Methyl-accepting chemotaxis BAZ_00406 ENOG4105CI1 PTS System BAZ_00412 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAZ_00415 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAZ_00418 ENOG4105C5H ABC transporter BAZ_00423 ENOG41062JF Transcriptional regulator BAZ_00427 ENOG4105DEU major facilitator superfamily BAZ_00430 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BAZ_00433 ENOG4108N0M stress protein BAZ_00434 ENOG4106FN3 tellurium resistance protein BAZ_00435 ENOG4106FN3 tellurium resistance protein BAZ_00436 ENOG4107TS3 membrane protein, TerC BAZ_00437 ENOG4108TTB tellurium resistance protein BAZ_00441 ENOG4105KJF protein tyrosine phosphatase BAZ_00443 ENOG4107U9T Pfam:Ribonuclease_BN BAZ_00444 ENOG4105C59 p-type ATPase BAZ_00445 ENOG4105C59 p-type ATPase BAZ_00446 ENOG4108IPJ Membrane BAZ_00448 ENOG4105C3F Signal peptidase i BAZ_00451 ENOG4107ZTW SNARE associated Golgi BAZ_00454 ENOG410606W general stress protein BAZ_00455 ENOG4105UPD Calcium Proton BAZ_00463 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAZ_00464 ENOG4105VTR Integrase BAZ_00522 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAZ_00524 ENOG4108JUB Transcriptional regulator BAZ_00526 ENOG4108IQI permease BAZ_00532 ENOG4105CSV Glutaminase BAZ_00534 ENOG4108A04 Beta-lactamase BAZ_00537 ENOG4105CKK Glycosyl transferase, family 2 BAZ_00539 ENOG4107QQG Dehydrogenase BAZ_00540 ENOG4105C3I Nad-dependent epimerase dehydratase BAZ_00543 ENOG4105F1A Pyruvate formate-lyase BAZ_00547 ENOG4105CI2 imidazolone-5-propionate hydrolase BAZ_00548 ENOG4105ECP epimerase BAZ_00554 ENOG41067AE Membrane-bound metal-dependent hydrolase BAZ_00555 ENOG4105CEN a g-specific adenine glycosylase BAZ_00556 ENOG4106BXE BAZ_00560 ENOG4105BZ1 (ABC) transporter BAZ_00561 ENOG4107NBY Membrane BAZ_00562 ENOG4105CBC glutamate synthase BAZ_00564 ENOG4108IUW ABC transporter BAZ_00568 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAZ_00569 ENOG4105G5W regulator Fur family BAZ_00592 ENOG4108JQC penicillin-binding protein 1A BAZ_00593 ENOG4107ZQN disulfide bond BAZ_00595 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAZ_00597 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAZ_00598 ENOG4105BZU Histidine kinase BAZ_00600 ENOG4105CYN Serine protein kinase BAZ_00604 ENOG4105C94 Transporter BAZ_00607 ENOG4105DZ6 Band 7 protein BAZ_00609 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAZ_00610 ENOG4108MRH transcriptional regulatory protein BAZ_00611 ENOG4105D4T Citrate transporter BAZ_00615 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAZ_00616 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAZ_00617 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAZ_00618 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BAZ_00619 ENOG4105BZ7 extracellular solute-binding protein family 1 BAZ_00620 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BAZ_00621 ENOG4108STX response regulator BAZ_00622 ENOG4105US7 Histidine kinase BAZ_00627 ENOG4108MRH transcriptional regulatory protein BAZ_00629 ENOG4105C6K Malic enzyme BAZ_00631 ENOG4108UZ3 Transporter BAZ_00632 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAZ_00634 ENOG4105BZU Histidine kinase BAZ_00635 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_00637 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAZ_00638 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAZ_00639 ENOG4108JB9 formate dehydrogenase BAZ_00644 ENOG4105CUB amino acid BAZ_00646 ENOG4105C59 p-type ATPase BAZ_00647 ENOG4105DAP Nicotinate phosphoribosyltransferase BAZ_00654 ENOG41073R8 VanW family BAZ_00655 ENOG4108KGH TRANSCRIPTIONal BAZ_00656 ENOG4105D9N nucleoside BAZ_00657 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAZ_00658 ENOG4105C37 (CBS) domain BAZ_00659 ENOG4108IJ0 Aspartate ammonia-lyase BAZ_00660 ENOG4105DAA L-lactate BAZ_00663 ENOG4105DUX Transporter BAZ_00664 ENOG4108MES Periplasmic binding protein BAZ_00665 ENOG4105DQ5 transport system permease protein BAZ_00666 ENOG4108IHU transport system permease protein BAZ_00667 ENOG4105E0A ABC, transporter BAZ_00668 ENOG4105DMQ Methyltransferase BAZ_00670 ENOG4105EXW epimerase dehydratase BAZ_00672 ENOG4107T89 von Willebrand factor, type A BAZ_00673 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAZ_00674 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAZ_00677 ENOG4105BZU Histidine kinase BAZ_00678 ENOG4105D5Q Arginine ornithine antiporter BAZ_00679 ENOG4107414 GntR family transcriptional regulator BAZ_00680 ENOG4105C5Y PTS System BAZ_00681 ENOG4105CG3 alpha amylase, catalytic region BAZ_00684 ENOG4105E1K spore germination protein BAZ_00686 ENOG4105CRN Aminoglycoside phosphotransferase BAZ_00687 ENOG4105BZG amino acid carrier protein BAZ_00688 ENOG4105CDA abc transporter atp-binding protein BAZ_00689 ENOG4105CT1 (ABC) transporter BAZ_00690 ENOG4105EAD ABC transporter BAZ_00691 ENOG4105DRP amino acid AbC transporter BAZ_00692 ENOG4108IQI permease BAZ_00697 ENOG4105D29 Helix-turn-helix type 11 domain protein BAZ_00698 ENOG4105NAE bifunctional deaminase-reductase domain protein BAZ_00699 ENOG4105BZU Histidine kinase BAZ_00702 ENOG4105CHH sulfate transporter BAZ_00703 ENOG41068KF Universal stress protein BAZ_00705 ENOG4105DEF Extracellular solute-binding protein, family 5 BAZ_00707 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAZ_00708 ENOG4108JQ7 (ABC) transporter BAZ_00710 ENOG4105CXY transporter BAZ_00711 ENOG41067TZ transcriptional regulator, MarR family BAZ_00712 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_00713 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_00714 ENOG4105ETE Transcriptional regulator (LacI family BAZ_00715 ENOG4108RVA ribokinase BAZ_00717 ENOG4105C2J ABC transporter BAZ_00718 ENOG4105CNN ABC, transporter BAZ_00719 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAZ_00720 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAZ_00732 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAZ_00733 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAZ_00734 ENOG41069ER domain protein BAZ_00735 ENOG4105VZ8 Transcriptional regulator BAZ_00736 ENOG4107D63 BAZ_00738 ENOG4105DUX Transporter BAZ_00742 ENOG4105C85 amino acid BAZ_00743 ENOG4105C7N Xanthine uracil vitamin C permease BAZ_00751 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAZ_00752 ENOG4105E2S oxidase) subunit II BAZ_00755 ENOG4106CAD Protein of unknown function (DUF3311) BAZ_00756 ENOG4105E1V na solute symporter BAZ_00759 ENOG4108NHD germination protein BAZ_00760 ENOG4105CE1 Ferrous iron transport protein b BAZ_00761 ENOG4105CE1 Ferrous iron transport protein b BAZ_00762 ENOG4105CE1 Ferrous iron transport protein b BAZ_00763 ENOG4105CVA phosphate BAZ_00764 ENOG4105C8U phosphate abc transporter BAZ_00765 ENOG4105E2Z phosphate ABC transporter (Permease BAZ_00791 ENOG41080XQ Signal transduction protein with cbs domains BAZ_00795 ENOG4105ETU transcriptional activator (TenA BAZ_00797 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAZ_00799 ENOG4108VEU Thiamine monophosphate synthase BAZ_00800 ENOG41080HI glycine oxidase BAZ_00803 ENOG4105D06 uba thif-type nad fad binding protein BAZ_00804 ENOG4105DWF phosphomethylpyrimidine kinase BAZ_00813 ENOG4108INS Transcriptional regulator BAZ_00816 ENOG4105C7N Xanthine uracil vitamin C permease BAZ_00823 ENOG4105C5Y PTS System BAZ_00830 ENOG4108B31 Spore germination protein BAZ_00835 ENOG4107Y03 Nitroreductase BAZ_00836 ENOG4105ED1 spovr family BAZ_00841 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BAZ_00842 ENOG4105XTG Pfam:DUF156 BAZ_00843 ENOG4105VFE sira family BAZ_00844 ENOG4107TPS domain protein BAZ_00845 ENOG4105VFE sira family BAZ_00847 ENOG41085GJ domain protein BAZ_00849 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BAZ_00850 ENOG41087NI Sulfite exporter TauE/SafE BAZ_00852 ENOG4108KGH TRANSCRIPTIONal BAZ_00857 ENOG4105EMD TRANSCRIPTIONal BAZ_00858 ENOG4105VCP PTS System BAZ_00859 ENOG4105VZJ PTS System BAZ_00863 ENOG41069ER domain protein BAZ_00864 ENOG4107RBB ABC transporter, permease BAZ_00865 ENOG4105C19 ABC transporter BAZ_00871 ENOG4105WEF catalase BAZ_00878 ENOG4107T5V SNARE associated Golgi BAZ_00885 ENOG4105CUB amino acid BAZ_00886 ENOG4107RWR Sodium hydrogen exchanger BAZ_00888 ENOG4106KNT transcriptional regulator BAZ_00895 ENOG4108PCN EamA-like transporter family BAZ_00896 ENOG4108YXU transcriptional regulator AsnC family BAZ_00898 ENOG4105KPY Small multidrug resistance protein BAZ_00899 ENOG4105KPY Small multidrug resistance protein BAZ_00904 ENOG4105NF4 modulator of drug activity BAZ_00905 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAZ_00906 ENOG4105E5W Transporter BAZ_00908 ENOG4107RKG DJ-1/PfpI family BAZ_00909 ENOG4105CH6 catalase BAZ_00911 ENOG4105D5Q Arginine ornithine antiporter BAZ_00912 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAZ_00914 ENOG4105C26 Dehydrogenase BAZ_00915 ENOG4105BZ1 (ABC) transporter BAZ_00916 ENOG4105BZ1 (ABC) transporter BAZ_00917 ENOG4105BZ1 (ABC) transporter BAZ_00919 ENOG4105DRP amino acid AbC transporter BAZ_00920 ENOG4105CDA abc transporter atp-binding protein BAZ_00923 ENOG410839P BAZ_00930 ENOG4107FQX Alpha-acetolactate decarboxylase BAZ_00935 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAZ_00937 ENOG4105D4P Coproporphyrinogen iii oxidase BAZ_00940 ENOG4105CHH sulfate transporter BAZ_00948 ENOG4106AKK s-layer domain-containing protein BAZ_00950 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAZ_00951 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAZ_00954 ENOG4105CGU Enoyl-CoA hydratase BAZ_00957 ENOG4105DER m42 family BAZ_00961 ENOG4105CTU Proline racemase BAZ_00969 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAZ_00972 ENOG4108JQ7 (ABC) transporter BAZ_00978 ENOG4105CSH Transporter BAZ_00980 ENOG4108MRH transcriptional regulatory protein BAZ_00989 ENOG4105CDU Replicative dna helicase BAZ_00997 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_01007 ENOG4107P5I polyketide synthase BAZ_01008 ENOG4108IG5 Transcriptional regulator BAZ_01012 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAZ_01016 ENOG4105CMT Dihydroxyacetone kinase BAZ_01018 ENOG4105CMT Dihydroxyacetone kinase BAZ_01019 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAZ_01020 ENOG410847I Transcriptional regulator, BadM Rrf2 family BAZ_01025 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BAZ_01038 ENOG4105WN5 stage II sporulation protein BAZ_01040 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_01042 ENOG4108MJI response regulator BAZ_01043 ENOG4105BZU Histidine kinase BAZ_01044 ENOG4105BZU Histidine kinase BAZ_01049 ENOG4105K8R UPF0145 protein BAZ_01055 ENOG4107VRP DNA repair exonuclease BAZ_01056 ENOG4106D4I domain protein BAZ_01057 ENOG4105D7V transposase BAZ_01060 ENOG4108IND Tetr family transcriptional regulator BAZ_01061 ENOG4105EQ0 Major Facilitator superfamily BAZ_01066 ENOG4108MUZ hydrolase BAZ_01070 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAZ_01073 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAZ_01076 ENOG4105EMN RNA polymerase sigma factor BAZ_01081 ENOG4105C57 major facilitator superfamily BAZ_01082 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_01084 ENOG4105EEM helicase BAZ_01085 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAZ_01090 ENOG4105K59 histidine triad (HIT) protein BAZ_01097 ENOG410905X membrane-flanked domain protein BAZ_01099 ENOG4105CKV Membrane BAZ_01109 ENOG410905X membrane-flanked domain protein BAZ_01110 ENOG4105CKV Membrane BAZ_01111 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAZ_01112 ENOG4105BZ4 penicillin-binding protein BAZ_01113 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAZ_01115 ENOG4105C1Q protoporphyrinogen oxidase BAZ_01120 ENOG4105NA0 Transcriptional regulator BAZ_01123 ENOG4105ECB domain protein BAZ_01129 ENOG4106AXD BAZ_01130 ENOG4108RQ5 Beta-lactamase domain-containing protein BAZ_01131 ENOG4105DF9 Lipoate-protein, ligase BAZ_01133 ENOG4105CEY Amp-dependent synthetase and ligase BAZ_01139 ENOG4105CNA YD repeat protein BAZ_01144 ENOG4105ENX hydrolase BAZ_01146 ENOG4107RN3 metallophosphoesterase BAZ_01147 ENOG4107TVP HD domain protein BAZ_01149 ENOG4108AEY RNA polymerase sigma factor BAZ_01150 ENOG41086D8 Transcriptional regulator BAZ_01154 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAZ_01159 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAZ_01161 ENOG4105C8Q Methyl-accepting chemotaxis BAZ_01165 ENOG4105ZU5 s-layer protein BAZ_01166 ENOG4107QP3 malate synthase g BAZ_01169 ENOG4105VEQ Cold shock protein BAZ_01172 ENOG4105XVF Competence transcription factor BAZ_01175 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAZ_01176 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAZ_01184 ENOG4105ERH Fumarylacetoacetate hydrolase BAZ_01189 ENOG4105CAQ asparagine synthetase BAZ_01190 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAZ_01191 ENOG4105CH6 catalase BAZ_01192 ENOG4105BZU Histidine kinase BAZ_01196 ENOG4105QNR S1 RNA binding domain protein BAZ_01198 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAZ_01200 ENOG4107AYK membrAne BAZ_01201 ENOG41073B9 BAZ_01203 ENOG4108KP7 hydrolase BAZ_01205 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAZ_01210 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAZ_01211 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAZ_01214 ENOG4105C31 Tryptophanyl-tRNA synthetase BAZ_01217 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAZ_01218 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAZ_01220 ENOG4108JQ7 (ABC) transporter BAZ_01221 ENOG4105UQX Mate efflux family protein BAZ_01225 ENOG4108ZCF integral membrane protein BAZ_01227 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAZ_01229 ENOG4105DPN Oligoendopeptidase f BAZ_01232 ENOG4108Z18 K06886 hemoglobin BAZ_01233 ENOG4105MIX Adenylate cyclase BAZ_01236 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAZ_01237 ENOG4105EMS pseudouridine synthase BAZ_01240 ENOG4105CNI cell division protein FtsW BAZ_01242 ENOG4105K64 Glycosyl transferase, family 2 BAZ_01246 ENOG4107TVC Glycosyl transferase, family 2 BAZ_01250 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAZ_01251 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BAZ_01253 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAZ_01260 ENOG4105ENA helicase BAZ_01261 ENOG4105C4R Atp-dependent dna helicase BAZ_01263 ENOG4108WVJ 2'-5' rna ligase BAZ_01268 ENOG4105CK7 Sodium proline symporter BAZ_01269 ENOG4105CRQ synthase (Component I) BAZ_01270 ENOG4105DDQ anthranilate synthase BAZ_01288 ENOG4105C7S Dehydrogenase BAZ_01290 ENOG4105VZ8 Transcriptional regulator BAZ_01301 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BAZ_01303 ENOG4105DZ1 carboxypeptidase BAZ_01304 ENOG4105VFR signal peptidase BAZ_01310 ENOG4105C26 Dehydrogenase BAZ_01311 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAZ_01312 ENOG4105F38 ABC transporter, permease BAZ_01313 ENOG4105D38 putrescine abc transporter BAZ_01314 ENOG4107RUE extracellular solute-binding protein family 1 BAZ_01316 ENOG4105EYF MMPL domain protein BAZ_01318 ENOG4108YBP pseudouridine synthase BAZ_01320 ENOG4105K4I Scp-like extracellular BAZ_01321 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAZ_01322 ENOG4105CQB FAD linked oxidase domain protein BAZ_01325 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_01326 ENOG4105BZU Histidine kinase BAZ_01327 ENOG4105JXH GntR family transcriptional regulator BAZ_01331 ENOG4106A3R peptidase BAZ_01333 ENOG4108QTI )-transporter BAZ_01334 ENOG4107TS3 membrane protein, TerC BAZ_01335 ENOG4105CZN Potassium uptake protein BAZ_01336 ENOG410681C small acid-soluble spore protein BAZ_01337 ENOG4108Z7G MaoC domain protein dehydratase BAZ_01341 ENOG4105CHR reductase BAZ_01343 ENOG4105MWK D-amino acid dehydrogenase, small subunit BAZ_01347 ENOG4105C4Y ABC transporter BAZ_01349 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAZ_01352 ENOG4107RCV ABC transporter, permease BAZ_01353 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BAZ_01357 ENOG4105E98 transcriptional regulator DeoR family BAZ_01362 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAZ_01363 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAZ_01365 ENOG4105PXI polysaccharide deacetylase BAZ_01367 ENOG4105BZU Histidine kinase BAZ_01368 ENOG41090MY MarR family Transcriptional regulator BAZ_01370 ENOG4106DF1 BAZ_01372 ENOG4105BZU Histidine kinase BAZ_01374 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BAZ_01375 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAZ_01383 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BAZ_01384 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAZ_01386 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAZ_01387 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAZ_01388 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAZ_01389 ENOG4105CZV ABC transporter BAZ_01391 ENOG4105CJ1 ABC, transporter BAZ_01399 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAZ_01400 ENOG4105EA8 2-Nitropropane dioxygenase BAZ_01401 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAZ_01403 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAZ_01408 ENOG4105NQC Flavodoxin BAZ_01415 ENOG4107QMU Mate efflux family protein BAZ_01416 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAZ_01422 ENOG4105CZN Potassium uptake protein BAZ_01423 ENOG41063Y9 BAZ_01424 ENOG4105KBJ sporulation protein ytfj BAZ_01429 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAZ_01430 ENOG4105C7K acetolactate synthase BAZ_01431 ENOG4108ZP8 Acetolactate synthase small subunit BAZ_01432 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAZ_01434 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAZ_01439 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAZ_01446 ENOG4107RVV histidinol phosphate phosphatase, hisj family BAZ_01449 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAZ_01450 ENOG4105E0M Sulfatase BAZ_01452 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAZ_01456 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAZ_01457 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAZ_01459 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAZ_01460 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAZ_01461 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAZ_01462 ENOG4105C8J )-transporter BAZ_01466 ENOG4105DFD Na H antiporter BAZ_01470 ENOG4105ENE Histidine kinase BAZ_01471 ENOG4105WH1 Two component transcriptional regulator luxr family BAZ_01475 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BAZ_01480 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAZ_01484 ENOG4105CJ3 phosphate transporter BAZ_01485 ENOG4107GRR phosphate transport regulator BAZ_01486 ENOG4105BZ4 penicillin-binding protein BAZ_01489 ENOG4105BZU Histidine kinase BAZ_01490 ENOG4105I3N Conserved Protein BAZ_01493 ENOG4105BZU Histidine kinase BAZ_01501 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAZ_01502 ENOG4105DZ1 carboxypeptidase BAZ_01503 ENOG4108JIC nucleoside recognition domain protein BAZ_01505 ENOG4105FE9 pseudouridine synthase BAZ_01507 ENOG4107TWT Cytochrome c biogenesis protein BAZ_01508 ENOG4105CRE cytochrome C BAZ_01509 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_01510 ENOG4105BZU Histidine kinase BAZ_01511 ENOG4108WBT adenosyltransferase BAZ_01514 ENOG4108SAX Membrane BAZ_01516 ENOG4105T7X BAZ_01517 ENOG4105C9U ATP-dependent DNA helicase RecQ BAZ_01518 ENOG4105I7S Abortive infection protein BAZ_01520 ENOG4107RGJ metallophosphoesterase BAZ_01521 ENOG4107X2D transcriptional regulator, merr family BAZ_01522 ENOG4108S6Z Negative regulator of genetic competence BAZ_01527 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAZ_01528 ENOG4107RB3 L-asparaginase BAZ_01535 ENOG4105S2F BAZ_01536 ENOG41065D1 BAZ_01542 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAZ_01545 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAZ_01547 ENOG4105EAH synthase BAZ_01551 ENOG4105CIH Imidazole acetol-phosphate transaminase BAZ_01552 ENOG41068YB TPR repeat-containing protein BAZ_01555 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BAZ_01556 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAZ_01557 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BAZ_01563 ENOG4108JYZ YitT family BAZ_01564 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAZ_01567 ENOG4105FJR Lmbe family BAZ_01568 ENOG4105CPK Glycosyl transferase (Group 1 BAZ_01575 ENOG4105DVT helicase BAZ_01576 ENOG4105YAC BAZ_01580 ENOG4105CSM endonuclease III BAZ_01582 ENOG4105BZ4 penicillin-binding protein BAZ_01593 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAZ_01595 ENOG4105DVT helicase BAZ_01596 ENOG4105CTD carboxy-peptidase BAZ_01599 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAZ_01601 ENOG4105C2W permease BAZ_01602 ENOG4105DHF Membrane BAZ_01604 ENOG410890F Dynamin family BAZ_01606 ENOG4108W0I acetyltransferase BAZ_01608 ENOG4105KHC sulfurtransferase BAZ_01611 ENOG4106032 Glutathionylspermidine synthase BAZ_01624 ENOG4105CPK Glycosyl transferase (Group 1 BAZ_01627 ENOG4108SZE gCN5-related N-acetyltransferase BAZ_01631 ENOG41081VK Ribonuclease BAZ_01644 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAZ_01646 ENOG4107RWR Sodium hydrogen exchanger BAZ_01647 ENOG4105CN5 Metallo-Beta-Lactamase BAZ_01648 ENOG4108Z5V transcriptional regulator, merr family BAZ_01650 ENOG4105H67 Protein of unknown function (DUF421) BAZ_01651 ENOG41080C8 DUF218 domain BAZ_01662 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAZ_01664 ENOG4107R0U MotA TolQ exbB proton channel BAZ_01665 ENOG4105ER2 Ompa motb domain protein BAZ_01666 ENOG4107YTP response regulator receiver protein BAZ_01667 ENOG4105CBS Chea signal transduction histidine kinase BAZ_01668 ENOG4105CBS Chea signal transduction histidine kinase BAZ_01669 ENOG4105DD5 Flagellar motor switch protein BAZ_01672 ENOG4105BZU Histidine kinase BAZ_01676 ENOG4105E1Q flagellar hook-associated protein BAZ_01677 ENOG4105DTJ flagellar hook-associated protein BAZ_01682 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAZ_01683 ENOG4108ZC9 flagellar basal-body rod protein flgc BAZ_01684 ENOG41075Z6 flagellar hook-basal body complex protein fliE BAZ_01685 ENOG4107U2N Flagellar M-ring protein BAZ_01687 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAZ_01694 ENOG4105BZE flagellar hook protein, FlgE BAZ_01698 ENOG4107R88 Chemotaxis protein (CheV) BAZ_01700 ENOG4105K64 Glycosyl transferase, family 2 BAZ_01706 ENOG4107TVC Glycosyl transferase, family 2 BAZ_01711 ENOG4105I03 Flagellin BAZ_01712 ENOG4105E4C Lytic transglycosylase catalytic BAZ_01713 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAZ_01715 ENOG4105DD5 Flagellar motor switch protein BAZ_01717 ENOG4105CN7 Flagellar biosynthetic protein FliP BAZ_01718 ENOG4105VS8 Flagellar biosynthetic protein fliq BAZ_01720 ENOG4105D00 flagellar biosynthetic protein flhB BAZ_01721 ENOG4105D7B Flagellar biosynthesis protein flha BAZ_01722 ENOG4105FZW flagellar biosynthesis regulator FlhF BAZ_01723 ENOG4105KTQ flagellar basal-body rod protein BAZ_01724 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAZ_01729 ENOG4108RZE Tetr family transcriptional regulator BAZ_01733 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAZ_01738 ENOG4105DUM transcriptional regulator, lysR family BAZ_01739 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAZ_01740 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAZ_01741 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BAZ_01742 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAZ_01749 ENOG4105CVJ phosphoglycerate mutase BAZ_01756 ENOG4105CAQ asparagine synthetase BAZ_01760 ENOG4105PGM cation diffusion facilitator family transporter BAZ_01762 ENOG4105DRR Transcriptional regulator, GntR family BAZ_01763 ENOG4108UZ3 Transporter BAZ_01764 ENOG4105CKI cobalamin synthesis protein BAZ_01765 ENOG4108PJD permease BAZ_01768 ENOG4105DFD Na H antiporter BAZ_01769 ENOG4105C9Q fumarate hydratase class II BAZ_01773 ENOG4107QJQ Mate efflux family protein BAZ_01774 ENOG4107QJQ Mate efflux family protein BAZ_01775 ENOG4105EC3 peptidase S51, dipeptidase E BAZ_01779 ENOG4107QIV Cytochrome c biogenesis protein BAZ_01786 ENOG4106BRA Membrane BAZ_01793 ENOG4105CJ1 ABC, transporter BAZ_01797 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAZ_01799 ENOG4108IJ0 Aspartate ammonia-lyase BAZ_01800 ENOG4105C6K Malic enzyme BAZ_01815 ENOG4105FVX BAZ_01823 ENOG4105CSR polyphosphate kinase 2 BAZ_01824 ENOG4105DXI Major Facilitator superfamily BAZ_01825 ENOG4105DXI Major Facilitator superfamily BAZ_01828 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAZ_01831 ENOG4105EU0 Major facilitator Superfamily BAZ_01832 ENOG4105C6T cysteine synthase BAZ_01836 ENOG4105C8J )-transporter BAZ_01838 ENOG4105X5K response regulator receiver protein BAZ_01839 ENOG4105H67 Protein of unknown function (DUF421) BAZ_01842 ENOG4106KE4 Dehydrogenase BAZ_01846 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAZ_01847 ENOG4105CHR reductase BAZ_01848 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAZ_01849 ENOG4105C7K acetolactate synthase BAZ_01850 ENOG4108ZP8 Acetolactate synthase small subunit BAZ_01851 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAZ_01853 ENOG4105C7B Threonine dehydratase BAZ_01858 ENOG4105C6X Major Facilitator BAZ_01859 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BAZ_01861 ENOG4105DY9 regulatoR BAZ_01862 ENOG4105CYC Transferase BAZ_01866 ENOG4105F6J Alpha beta hydrolase fold BAZ_01867 ENOG4108J59 Extracellular solute-binding protein, family 5 BAZ_01873 ENOG41068WN BAZ_01878 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAZ_01879 ENOG4105C72 UPF0176 protein BAZ_01881 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAZ_01883 ENOG4105C0X amino acid BAZ_01884 ENOG4105C0X amino acid BAZ_01889 ENOG4107RHR regulatoR BAZ_01891 ENOG4105D9N nucleoside BAZ_01892 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAZ_01898 ENOG4107RAQ aminopeptidase BAZ_01899 ENOG4107STQ Multicopper oxidase BAZ_01909 ENOG4108T5E Copper resistance protein BAZ_01910 ENOG4105KTB nuclear export factor GLE1 BAZ_01912 ENOG4107RT3 EamA-like transporter family BAZ_01913 ENOG4105GZI Transcriptional regulator BAZ_01914 ENOG4108Z40 Transcriptional regulator BAZ_01915 ENOG4107ZXU DSBA oxidoreductase BAZ_01916 ENOG4108TVJ Nitroreductase BAZ_01918 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAZ_01919 ENOG4106F5Q Membrane BAZ_01920 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAZ_01922 ENOG4105CKI cobalamin synthesis protein BAZ_01926 ENOG4108Z7G MaoC domain protein dehydratase BAZ_01927 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAZ_01929 ENOG4105C0Z ABC transporter BAZ_01930 ENOG4108IV0 ABC, transporter BAZ_01931 ENOG4105C32 Amino acid ABC transporter (Permease) BAZ_01933 ENOG4105SKE transcriptional Regulator LysR family BAZ_01937 ENOG4105YGB Transcriptional regulator BAZ_01939 ENOG4105C4M (Ubiquinol oxidase) subunit I BAZ_01940 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAZ_01941 ENOG4108JJ9 ABC, transporter BAZ_01942 ENOG4108JJ8 (ABC) transporter BAZ_01950 ENOG4105BZ1 (ABC) transporter BAZ_01951 ENOG4105BZ1 (ABC) transporter BAZ_01952 ENOG4105EFI regulatoR BAZ_01953 ENOG4105BZU Histidine kinase BAZ_01956 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAZ_01957 ENOG4108ZJ4 polysaccharide deacetylase BAZ_01961 ENOG4105D6E homoserine dehydrogenase BAZ_01966 ENOG4108KGH TRANSCRIPTIONal BAZ_01968 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAZ_01969 ENOG4105BZU Histidine kinase BAZ_01970 ENOG4107VMI polysaccharide deacetylase BAZ_01972 ENOG4105KT7 mgtC SapB transporter BAZ_01973 ENOG4105VRR gCN5-related N-acetyltransferase BAZ_01975 ENOG4105DUU IucA IucC family protein BAZ_01976 ENOG4105CEY Amp-dependent synthetase and ligase BAZ_01979 ENOG4108WBH protein TIM barrel BAZ_01980 ENOG4105YWU small acid-soluble spore protein BAZ_01981 ENOG4107RCC Major Facilitator Superfamily BAZ_01983 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAZ_01994 ENOG4105KRN Transcriptional regulator, abrb family BAZ_01996 ENOG4105YVS arsR family transcriptional regulator BAZ_01997 ENOG4107SET aldo keto reductase BAZ_01998 ENOG4107XZQ multidrug resistance protein BAZ_02003 ENOG4105C8Q Methyl-accepting chemotaxis BAZ_02006 ENOG4108K88 Membrane BAZ_02007 ENOG4108WPJ Ferritin-like domain BAZ_02010 ENOG4105DEN Luciferase family BAZ_02014 ENOG4107QM2 Aldo Keto reductase BAZ_02015 ENOG4105CKI cobalamin synthesis protein BAZ_02026 ENOG4105DSE periplasmic solute binding protein BAZ_02028 ENOG4105K4T epimerase BAZ_02030 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAZ_02035 ENOG4105CVJ phosphoglycerate mutase BAZ_02039 ENOG4107T5V SNARE associated Golgi BAZ_02042 ENOG4108PJD permease BAZ_02044 ENOG4108S4H thioesterase Superfamily protein BAZ_02045 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAZ_02049 ENOG4105SXS Protein of unknown function (DUF456) BAZ_02050 ENOG4105C37 (CBS) domain BAZ_02054 ENOG4108Z7R Chaperone CsaA BAZ_02058 ENOG4108ZRV stage ii sporulation protein p BAZ_02060 ENOG4108VXD carboxy-peptidase BAZ_02062 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAZ_02067 ENOG4108X4Q Hydrolase BAZ_02069 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAZ_02070 ENOG4107RBS Methyltransferase BAZ_02073 ENOG41087PP glycosyltransferase MGT family BAZ_02074 ENOG4108JYZ YitT family BAZ_02076 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAZ_02082 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAZ_02091 ENOG4105KBJ sporulation protein ytfj BAZ_02095 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAZ_02099 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAZ_02100 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_02102 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BAZ_02103 ENOG4105EMN RNA polymerase sigma factor BAZ_02108 ENOG4108V06 Glutathione peroxidase BAZ_02111 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAZ_02115 ENOG4108IUE nitrate reductase beta subunit BAZ_02116 ENOG4105R3A Nitrate reductase BAZ_02121 ENOG4107V6Q Cyclic nucleotide-binding domain BAZ_02122 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAZ_02123 ENOG4105D06 uba thif-type nad fad binding protein BAZ_02124 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAZ_02125 ENOG4108ZAF Molybdopterin BAZ_02130 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAZ_02131 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAZ_02132 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAZ_02133 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAZ_02134 ENOG4108IFG nitrite reductase, (NAD(P)H) BAZ_02135 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BAZ_02142 ENOG4105MCT stage V sporulation protein S BAZ_02145 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAZ_02149 ENOG4105C5H ABC transporter BAZ_02152 ENOG4108UUM single-stranded DNA-binding protein BAZ_02155 ENOG41061H0 Monooxygenase BAZ_02159 ENOG4107YX5 Pfam:DUF548 BAZ_02160 ENOG4105C75 arginyL-tRNA synthetase BAZ_02166 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAZ_02169 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAZ_02170 ENOG4105C5S asparaginyl-tRNA synthetase BAZ_02174 ENOG4105EC2 ftsk spoIIIe BAZ_02193 ENOG4105BZW Glycerate kinase BAZ_02194 ENOG4107QPK )-transporter BAZ_02195 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_02196 ENOG41062D9 Histidine kinase BAZ_02199 ENOG4105C8J )-transporter BAZ_02203 ENOG4107XGZ Hydrolase BAZ_02204 ENOG4105CY2 Citrate transporter BAZ_02205 ENOG4105C0A alcohol dehydrogenase BAZ_02208 ENOG4105KD7 acetyltransferase BAZ_02210 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BAZ_02215 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BAZ_02219 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BAZ_02222 ENOG4107RVG penicillin-binding protein BAZ_02223 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAZ_02224 ENOG4105E9Q Acyl-transferase BAZ_02225 ENOG4108UT2 hemolysin iii BAZ_02227 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAZ_02229 ENOG4108RCR degv family BAZ_02230 ENOG4105E8R UPF0173 metal-dependent hydrolase BAZ_02231 ENOG4108KF3 Electron transport protein SCO1 SenC BAZ_02232 ENOG4107Y70 Heat shock protein BAZ_02233 ENOG4105CAQ asparagine synthetase BAZ_02237 ENOG4108MES Periplasmic binding protein BAZ_02238 ENOG4105F0I Aminotransferase BAZ_02245 ENOG4105D8X mechanosensitive ion channel BAZ_02246 ENOG4105BZU Histidine kinase BAZ_02247 ENOG4105WH1 Two component transcriptional regulator luxr family BAZ_02249 ENOG4106KNT transcriptional regulator BAZ_02257 ENOG4105CMG Carbohydrate kinase BAZ_02258 ENOG4105CMG Carbohydrate kinase BAZ_02264 ENOG4108IJ8 ABC transporter BAZ_02265 ENOG4105E90 ABC transporter BAZ_02272 ENOG4105C37 (CBS) domain BAZ_02277 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAZ_02280 ENOG4107S4Y M20 DapE family protein YgeY BAZ_02281 ENOG4108TSC N-acetyltransferase BAZ_02282 ENOG4108JUB Transcriptional regulator BAZ_02283 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAZ_02291 ENOG4108N23 SpoOM-related protein BAZ_02292 ENOG410841Q phosphoesterase PA-phosphatase related protein BAZ_02294 ENOG4105SZ6 Thioredoxin BAZ_02296 ENOG4108IBT Inherit from COG: transposase BAZ_02315 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAZ_02323 ENOG4105BZ4 penicillin-binding protein BAZ_02324 ENOG4105CZM Major Facilitator BAZ_02325 ENOG4105W8X HesB YadR YfhF-family protein BAZ_02327 ENOG4105DXD 2-methylcitrate dehydratase BAZ_02328 ENOG4105CR4 methylisocitrate lyase BAZ_02329 ENOG4105C1G acyl-Coa dehydrogenase BAZ_02330 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAZ_02332 ENOG4105N14 lysine exporter protein LysE YggA BAZ_02333 ENOG4105E39 Enoyl-CoA hydratase BAZ_02336 ENOG4107RFY SbcCD D subunit BAZ_02337 ENOG4105EYH Exonuclease BAZ_02341 ENOG4105FCD Major Facilitator BAZ_02342 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAZ_02343 ENOG4105E4F Isochorismate synthase BAZ_02344 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAZ_02345 ENOG4105WQI isochorismatase BAZ_02346 ENOG4105CEY Amp-dependent synthetase and ligase BAZ_02347 ENOG4105WQT MbtH domain protein BAZ_02348 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_02351 ENOG4105K70 DNA-binding protein BAZ_02355 ENOG4105BZG amino acid carrier protein BAZ_02359 ENOG4105FE9 pseudouridine synthase BAZ_02360 ENOG4105C22 threonyL-tRNA synthetase BAZ_02361 ENOG4105C19 ABC transporter BAZ_02364 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAZ_02370 ENOG4108D32 Methyltransferase BAZ_02376 ENOG41081I9 integral membrane protein BAZ_02377 ENOG41081I9 integral membrane protein BAZ_02380 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAZ_02382 ENOG4105EYF MMPL domain protein BAZ_02387 ENOG4105WCN acetyltransferase BAZ_02393 ENOG4105C1Q protoporphyrinogen oxidase BAZ_02395 ENOG41068WN BAZ_02397 ENOG4105VEQ Cold shock protein BAZ_02401 ENOG410667J hydrolase BAZ_02408 ENOG4107V2S Transcriptional regulator BAZ_02409 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAZ_02412 ENOG4105DND Transcriptional regulator BAZ_02413 ENOG4108RPX mosc domain containing protein BAZ_02416 ENOG4105BZ1 (ABC) transporter BAZ_02417 ENOG4105BZ1 (ABC) transporter BAZ_02421 ENOG4108JCI Transcriptional regulator BAZ_02426 ENOG4108KPJ rna polymerase sigma factor BAZ_02431 ENOG4105F32 YngK protein BAZ_02436 ENOG4105RD7 BadF BadG BcrA BcrD BAZ_02438 ENOG4107STF Involved in phosphonate degradation (By similarity) BAZ_02441 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAZ_02444 ENOG4105C1J atp-dependent rna helicase BAZ_02446 ENOG4108RZE Tetr family transcriptional regulator BAZ_02450 ENOG41088CC tellurite resistance protein tehB BAZ_02452 ENOG4108I0C methyltransferase BAZ_02453 ENOG4107RA9 decarboxylase BAZ_02454 ENOG41090HR transcriptional regulator BAZ_02460 ENOG4105CIN aminoacyl-histidine dipeptidase BAZ_02466 ENOG4107RF6 penicillin-binding protein BAZ_02467 ENOG4107RF6 penicillin-binding protein BAZ_02468 ENOG4107RF6 penicillin-binding protein BAZ_02470 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAZ_02471 ENOG4105ETE Transcriptional regulator (LacI family BAZ_02472 ENOG4105IE8 Alpha-ketoglutarate permease BAZ_02473 ENOG4105CK5 oxidoreductase BAZ_02478 ENOG4105D2N Aldolase BAZ_02479 ENOG4105DH8 myo-inositol catabolism BAZ_02483 ENOG4105CGH 5'-nucleotidase BAZ_02484 ENOG4105CGH 5'-nucleotidase BAZ_02487 ENOG4105VZ8 Transcriptional regulator BAZ_02490 ENOG4108VXD carboxy-peptidase BAZ_02494 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BAZ_02495 ENOG41067SE Tetr family transcriptional regulator BAZ_02496 ENOG4105C5H ABC transporter BAZ_02498 ENOG4105BZU Histidine kinase BAZ_02500 ENOG4106ANW SMI1_KNR4 BAZ_02501 ENOG4105CEP NADH dehydrogenase BAZ_02502 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BAZ_02505 ENOG4105CJ1 ABC, transporter BAZ_02507 ENOG4107Z3H Transcriptional regulator, TetR family BAZ_02510 ENOG4105C1G acyl-Coa dehydrogenase BAZ_02511 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAZ_02512 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAZ_02513 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAZ_02514 ENOG4105E39 Enoyl-CoA hydratase BAZ_02515 ENOG4107QX3 carboxylase BAZ_02516 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAZ_02518 ENOG4105WCN acetyltransferase BAZ_02519 ENOG4105DBI uridine monophosphokinase BAZ_02522 ENOG4105DZ1 carboxypeptidase BAZ_02525 ENOG4105T9C HD domain BAZ_02527 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BAZ_02536 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAZ_02536 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAZ_02539 ENOG4105FQP Beta-lactamase BAZ_02541 ENOG4107Y80 Major Facilitator superfamily BAZ_02545 ENOG4105CUV Homoserine Kinase BAZ_02551 ENOG4105CPQ Dehydrogenase BAZ_02554 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAZ_02576 ENOG4105ETU transcriptional activator (TenA BAZ_02600 ENOG410667J hydrolase BAZ_02602 ENOG4105BZU Histidine kinase BAZ_02603 ENOG4107RF6 penicillin-binding protein BAZ_02607 ENOG4108JJB ABC transporter BAZ_02610 ENOG4108HGU Histidine kinase BAZ_02613 ENOG4105CB2 alcohol dehydrogenase BAZ_02614 ENOG4105CJN penicillin-binding protein BAZ_02616 ENOG4105FQP Beta-lactamase BAZ_02622 ENOG4108V4B ThiJ pfpI BAZ_02627 ENOG4107Y80 Major Facilitator superfamily BAZ_02631 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAZ_02636 ENOG4107Y9U Membrane BAZ_02643 ENOG4105FCD Major Facilitator BAZ_02645 ENOG4105E09 nadh pyrophosphatase BAZ_02646 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAZ_02647 ENOG4108Z4K mutator MutT protein BAZ_02654 ENOG4108XI2 Domain of unknown function (DUF1963) BAZ_02660 ENOG4108NRW Phospholipase, patatin family BAZ_02661 ENOG4105KWG Pfam:DUF1696 BAZ_02668 ENOG4105PKS Excinuclease abc c subunit domain protein BAZ_02676 ENOG4107VFR oxidoreductase BAZ_02681 ENOG4105PAD Hydrolase BAZ_02686 ENOG4105DY8 decarboxylase BAZ_02689 ENOG4108IUM Glycogen debranching enzyme BAZ_02694 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAZ_02696 ENOG4105FDR Membrane BAZ_02703 ENOG4108V3A UPF0421 protein BAZ_02707 ENOG4105MSI germination protein ypeb BAZ_02711 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BAZ_02712 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BAZ_02713 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BAZ_02714 ENOG4107Z3H Transcriptional regulator, TetR family BAZ_02720 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAZ_02724 ENOG4105E98 transcriptional regulator DeoR family BAZ_02728 ENOG41062ES Transcriptional regulator BAZ_02733 ENOG4107QKR Dehydrogenase BAZ_02735 ENOG4107RUY (E1 component), alpha subunit BAZ_02737 ENOG4105E1F short-chain dehydrogenase reductase BAZ_02738 ENOG4105RHY Pfam:UPF0157 BAZ_02744 ENOG4107SQ8 Glycine betaine BAZ_02745 ENOG4108IJ7 Glycine betaine BAZ_02750 ENOG4105E66 phosphoriboisomerase A BAZ_02751 ENOG41082BV acetyltransferase BAZ_02752 ENOG4108M1A Chitin-binding protein BAZ_02761 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAZ_02767 ENOG4108Z7F N-acetyltransferase BAZ_02771 ENOG4105EEM helicase BAZ_02775 ENOG4105C9U ATP-dependent DNA helicase RecQ BAZ_02783 ENOG4108M1A Chitin-binding protein BAZ_02786 ENOG4105BZG amino acid carrier protein BAZ_02787 ENOG4105C26 Dehydrogenase BAZ_02788 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAZ_02789 ENOG4105CTU Proline racemase BAZ_02790 ENOG4105CTU Proline racemase BAZ_02791 ENOG41080HI glycine oxidase BAZ_02798 ENOG4107T5V SNARE associated Golgi BAZ_02801 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAZ_02802 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAZ_02805 ENOG4105DTQ mandelate racemase muconate lactonizing BAZ_02813 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BAZ_02814 ENOG4105BZU Histidine kinase BAZ_02815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_02822 ENOG4105DPN Oligoendopeptidase f BAZ_02825 ENOG4105EPR degv family BAZ_02833 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAZ_02834 ENOG4106K7D Major facilitator family transporter BAZ_02838 ENOG4107BMA Transglycosylase associated protein BAZ_02841 ENOG41089UC methyltransferase, type 11 BAZ_02847 ENOG4105CHM Aminotransferase BAZ_02853 ENOG4105DVE abc transporter atp-binding protein BAZ_02862 ENOG4105C02 permease BAZ_02864 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BAZ_02865 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAZ_02866 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAZ_02871 ENOG4105E09 nadh pyrophosphatase BAZ_02875 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BAZ_02885 ENOG4107VC0 DNA alkylation repair enzyme BAZ_02887 ENOG4107VMI polysaccharide deacetylase BAZ_02889 ENOG4108ZCF integral membrane protein BAZ_02890 ENOG4105E0M Sulfatase BAZ_02891 ENOG4105C5H ABC transporter BAZ_02893 ENOG4105EYF MMPL domain protein BAZ_02894 ENOG4105EYF MMPL domain protein BAZ_02895 ENOG41082JN Transcriptional regulator BAZ_02899 ENOG4105CIH Imidazole acetol-phosphate transaminase BAZ_02900 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAZ_02901 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAZ_02909 ENOG41069ER domain protein BAZ_02911 ENOG4105EMN RNA polymerase sigma factor BAZ_02917 ENOG4105D4B ABC, transporter BAZ_02919 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BAZ_02921 ENOG4105DKT Transcriptional regulator BAZ_02922 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BAZ_02925 ENOG41061GT Aldolase BAZ_02929 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAZ_02935 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAZ_02936 ENOG4105II7 pyrroline-5-carboxylate reductase BAZ_02938 ENOG4107258 Transcriptional regulator BAZ_02940 ENOG4105E0Y RtcB Protein BAZ_02941 ENOG4105ECK Fatty Acid Desaturase BAZ_02942 ENOG4105G6Z alkaline phosphatase BAZ_02944 ENOG4105VMP Transcriptional regulator BAZ_02947 ENOG41090T1 Membrane BAZ_02949 ENOG4108WCX response regulator BAZ_02951 ENOG41068WN BAZ_02956 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAZ_02961 ENOG4105CKK Glycosyl transferase, family 2 BAZ_02966 ENOG4105CKK Glycosyl transferase, family 2 BAZ_02969 ENOG4105C8Y Acetylornithine aminotransferase BAZ_02978 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAZ_02980 ENOG4108TVJ Nitroreductase BAZ_02981 ENOG4105FS7 Transcriptional regulator BAZ_02988 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAZ_02990 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BAZ_02996 ENOG4108XET gCN5-related N-acetyltransferase BAZ_03012 ENOG410635A Membrane BAZ_03013 ENOG4105KNA -acetyltransferase BAZ_03014 ENOG4108IQI permease BAZ_03016 ENOG4105F1N DNA alkylation repair BAZ_03025 ENOG4107RF6 penicillin-binding protein BAZ_03027 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAZ_03034 ENOG4105P4J Allophanate hydrolase, subunit 1 BAZ_03035 ENOG4107258 Transcriptional regulator BAZ_03037 ENOG4106N3A copper homeostasis protein cutc BAZ_03038 ENOG4108ZRV stage ii sporulation protein p BAZ_03039 ENOG4108ZHR arsR family transcriptional regulator BAZ_03041 ENOG4105FDT acyl-CoA dehydrogenase BAZ_03045 ENOG4105DWD nucleoside recognition domain protein BAZ_03051 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAZ_03052 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAZ_03067 ENOG4105E2A Dehydrogenase BAZ_03070 ENOG4108IJ0 Aspartate ammonia-lyase BAZ_03071 ENOG4105HDK L-asparaginase BAZ_03072 ENOG4108IMY Transcriptional regulator BAZ_03074 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAZ_03075 ENOG4105CUB amino acid BAZ_03077 ENOG4105II7 pyrroline-5-carboxylate reductase BAZ_03079 ENOG4105C6K Malic enzyme BAZ_03082 ENOG4108NHD germination protein BAZ_03083 ENOG4108NHD germination protein BAZ_03084 ENOG4108Q8B Spore germination protein BAZ_03089 ENOG4105CSV Glutaminase BAZ_03097 ENOG4105CGH 5'-nucleotidase BAZ_03098 ENOG4105CH6 catalase BAZ_03100 ENOG4105CHJ isochorismatase hydrolase BAZ_03106 ENOG41090MY MarR family Transcriptional regulator BAZ_03114 ENOG4108606 TspO/MBR family BAZ_03115 ENOG4105CVP deoxyribo-dipyrimidine photolyase BAZ_03118 ENOG4108TWJ NADH dehydrogenase subunit 5 BAZ_03119 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BAZ_03121 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAZ_03122 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BAZ_03123 ENOG4105DSE periplasmic solute binding protein BAZ_03124 ENOG4105CC5 ABC transporter BAZ_03125 ENOG4105DIK (ABC) transporter BAZ_03131 ENOG4105D6J arsenicaL-resistance protein BAZ_03132 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_03133 ENOG41085FC arsR family transcriptional regulator BAZ_03137 ENOG4105F7F Chaperone BAZ_03139 ENOG4105CHR reductase BAZ_03140 ENOG4108YXU transcriptional regulator AsnC family BAZ_03154 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAZ_03155 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_03157 ENOG4105IIP Membrane BAZ_03160 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_03161 ENOG41062D9 Histidine kinase BAZ_03166 ENOG4105K6H D-cysteine desulfhydrase BAZ_03172 ENOG4105VZ8 Transcriptional regulator BAZ_03175 ENOG4108NNI Beta-lactamase domain-containing protein BAZ_03176 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAZ_03178 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAZ_03179 ENOG4105JQZ Methyltransferase BAZ_03182 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAZ_03183 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BAZ_03186 ENOG4105BZU Histidine kinase BAZ_03189 ENOG4108U05 Transcriptional regulator BAZ_03190 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAZ_03192 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAZ_03193 ENOG4105DJB Major Facilitator Superfamily BAZ_03194 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BAZ_03195 ENOG4107QR9 Iron-sulfur cluster binding protein BAZ_03197 ENOG4106P55 Transcriptional regulator BAZ_03199 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAZ_03205 ENOG4105TRI Hydrolase BAZ_03213 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAZ_03220 ENOG4107QJQ Mate efflux family protein BAZ_03223 ENOG4105MZU cell filamentation protein BAZ_03224 ENOG4105EQ0 Major Facilitator superfamily BAZ_03225 ENOG4108JGH Tetr family transcriptional regulator BAZ_03228 ENOG4105C44 Serine transporter BAZ_03229 ENOG4105EJQ L-serine dehydratase BAZ_03231 ENOG4108JPW Aminotransferase BAZ_03234 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BAZ_03236 ENOG4105DVH amino acid BAZ_03239 ENOG4108JQ1 Dehydrogenase BAZ_03243 ENOG4108AEY RNA polymerase sigma factor BAZ_03246 ENOG41082W1 Cupin 2, conserved barrel domain protein BAZ_03247 ENOG410874W AraC family transcriptional regulator BAZ_03250 ENOG4105HIR S-layer domain protein BAZ_03258 ENOG4108ISG Major Facilitator BAZ_03260 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAZ_03261 ENOG4105CZM Major Facilitator BAZ_03265 ENOG4105DA5 (ABC) transporter BAZ_03266 ENOG41069JR BAZ_03268 ENOG4105RXJ BAZ_03269 ENOG4105KPY Small multidrug resistance protein BAZ_03270 ENOG4105KBX Transcriptional regulator, TetR family BAZ_03272 ENOG4105CRW Short chain fatty acid transporter BAZ_03274 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAZ_03280 ENOG4108JJB ABC transporter BAZ_03281 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAZ_03286 ENOG4108K8S endonuclease I BAZ_03289 ENOG41067QW Transcriptional regulator BAZ_03291 ENOG4108Z66 YbaK ebsC protein BAZ_03292 ENOG4105CUT histidyl-tRNA synthetase BAZ_03295 ENOG4105KVH Transcriptional regulator BAZ_03296 ENOG4108RCM Nitroreductase BAZ_03300 ENOG4108PSK reductase BAZ_03302 ENOG4105CJ1 ABC, transporter BAZ_03314 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_03315 ENOG4105DKQ ROK family BAZ_03316 ENOG4106UW1 Major Facilitator superfamily BAZ_03317 ENOG4108UW5 maltose o-acetyltransferase BAZ_03319 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAZ_03321 ENOG4105C31 Tryptophanyl-tRNA synthetase BAZ_03322 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAZ_03327 ENOG4105DMQ Methyltransferase BAZ_03329 ENOG4105EV4 Multidrug resistance protein mdtH BAZ_03335 ENOG4105C37 (CBS) domain BAZ_03338 ENOG4105DDN Pentapeptide repeat-containing protein BAZ_03339 ENOG4105XDF Protein of unknown function (DUF1272) BAZ_03340 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAZ_03341 ENOG4105CMG Carbohydrate kinase BAZ_03342 ENOG4105C6Z Gluconate BAZ_03343 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAZ_03346 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAZ_03347 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAZ_03348 ENOG4105CIS alcohol dehydrogenase BAZ_03349 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BAZ_03352 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAZ_03353 ENOG4105D4Y metalloprotease BAZ_03357 ENOG4105CV8 reductase BAZ_03358 ENOG4105F27 Major Facilitator BAZ_03361 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAZ_03362 ENOG4105C44 Serine transporter BAZ_03368 ENOG4105KVH Transcriptional regulator BAZ_03369 ENOG4108TZY GntR Family Transcriptional Regulator BAZ_03370 ENOG4105D9R oxidoreductase BAZ_03372 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BAZ_03373 ENOG4105KVH Transcriptional regulator BAZ_03374 ENOG4105KVH Transcriptional regulator BAZ_03381 ENOG4105JAB phenazine biosynthesis protein, phzf family BAZ_03383 ENOG4105CHR reductase BAZ_03387 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAZ_03388 ENOG4105KVH Transcriptional regulator BAZ_03392 ENOG4108ZJ4 polysaccharide deacetylase BAZ_03402 ENOG4105KAF membrAne BAZ_03407 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BAZ_03411 ENOG4107YXZ hydrolase, family 25 BAZ_03416 ENOG4105ED2 Beta-lactamase BAZ_03418 ENOG4105H3G oxidoreductase BAZ_03425 ENOG4105CIS alcohol dehydrogenase BAZ_03432 ENOG4108TN2 lmbE family BAZ_03434 ENOG4107R3E Citrate transporter BAZ_03438 ENOG4108MES Periplasmic binding protein BAZ_03440 ENOG4105EHG Permease protein BAZ_03441 ENOG4105DQ5 transport system permease protein BAZ_03442 ENOG4105NX3 Membrane BAZ_03443 ENOG4107ZY0 Phenazine biosynthesis-like protein BAZ_03447 ENOG4107CUJ Protein of unknown function (DUF2690) BAZ_03449 ENOG4107V2S Transcriptional regulator BAZ_03453 ENOG4105C98 muts2 protein BAZ_03455 ENOG4105E5K Alpha-amylase BAZ_03456 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAZ_03457 ENOG4105DPN Oligoendopeptidase f BAZ_03458 ENOG4108A04 Beta-lactamase BAZ_03464 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAZ_03468 ENOG41082BM Transcriptional regulator, arsr family BAZ_03469 ENOG4105CIS alcohol dehydrogenase BAZ_03475 ENOG4105RHY Pfam:UPF0157 BAZ_03477 ENOG4105C09 Bile acid BAZ_03478 ENOG4105CQB FAD linked oxidase domain protein BAZ_03482 ENOG4108UT6 Transferase hexapeptide repeat containing protein BAZ_03484 ENOG4105K64 Glycosyl transferase, family 2 BAZ_03485 ENOG4105E39 Enoyl-CoA hydratase BAZ_03487 ENOG4105KT7 mgtC SapB transporter BAZ_03489 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_03490 ENOG41073R8 VanW family BAZ_03492 ENOG4108R1P BAZ_03496 ENOG4105VEQ Cold shock protein BAZ_03500 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BAZ_03504 ENOG410904N short-chain dehydrogenase reductase BAZ_03506 ENOG4106IQC argininosuccinate lyase BAZ_03509 ENOG4108IA2 Sodium pantothenate symporter BAZ_03511 ENOG4105C26 Dehydrogenase BAZ_03512 ENOG4105CHR reductase BAZ_03514 ENOG4105EWU Squalene--hopene cyclase BAZ_03516 ENOG4105FR1 rard protein BAZ_03517 ENOG410696E Membrane BAZ_03520 ENOG4105D1F ATP-binding protein BAZ_03522 ENOG4108ZAF Molybdopterin BAZ_03523 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAZ_03524 ENOG4105D06 uba thif-type nad fad binding protein BAZ_03525 ENOG4105TMB Formate nitrite transporter BAZ_03527 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAZ_03528 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAZ_03530 ENOG4108JB9 formate dehydrogenase BAZ_03532 ENOG4105E1K spore germination protein BAZ_03544 ENOG4107QJT sodium dicarboxylate symporter BAZ_03545 ENOG4108KGH TRANSCRIPTIONal BAZ_03547 ENOG4105EMN RNA polymerase sigma factor BAZ_03551 ENOG4105CIG ABC transporter BAZ_03553 ENOG4105D9R oxidoreductase BAZ_03555 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAZ_03556 ENOG4105K4P CoA-binding domain protein BAZ_03557 ENOG4105C0H protease BAZ_03558 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_03560 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BAZ_03561 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAZ_03562 ENOG4105W8X HesB YadR YfhF-family protein BAZ_03568 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAZ_03569 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAZ_03571 ENOG4108JJA ABC, transporter BAZ_03572 ENOG4108I0Z Aconitate hydratase BAZ_03577 ENOG4105E5W Transporter BAZ_03579 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAZ_03583 ENOG4107F3J Amp-dependent synthetase and ligase BAZ_03584 ENOG4107ZYJ bioY protein BAZ_03585 ENOG4105CEY Amp-dependent synthetase and ligase BAZ_03594 ENOG4107AYK membrAne BAZ_03596 ENOG4105BZU Histidine kinase BAZ_03597 ENOG4105FBA Phospholipase Carboxylesterase BAZ_03598 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAZ_03599 ENOG4105CK7 Sodium proline symporter BAZ_03600 ENOG4105CBC glutamate synthase BAZ_03601 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAZ_03602 ENOG4108VJ1 Transcriptional regulator (CarD family BAZ_03603 ENOG4108903 Formimidoylglutamase BAZ_03608 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BAZ_03619 ENOG4107QIV Cytochrome c biogenesis protein BAZ_03621 ENOG4107RSM transcriptional regulator BAZ_03622 ENOG4105VAW lrga family BAZ_03623 ENOG41067MG lrgb family BAZ_03628 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAZ_03631 ENOG4105BZ1 (ABC) transporter BAZ_03632 ENOG4105BZ1 (ABC) transporter BAZ_03636 ENOG4105D7V transposase BAZ_03639 ENOG4105D5T phosphonate abc transporter BAZ_03642 ENOG4105CGH 5'-nucleotidase BAZ_03644 ENOG4108SVB resolvase BAZ_03648 ENOG4105K7K Transcriptional regulator BAZ_03656 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAZ_03657 ENOG4105XSJ toxin secretion phage lysis holin BAZ_03697 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BAZ_03718 ENOG4105C5F glutamine synthetase BAZ_03719 ENOG4105KV4 Transcriptional regulator BAZ_03720 ENOG4105CXI aluminum resistance protein BAZ_03721 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAZ_03722 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAZ_03723 ENOG4105EN6 Membrane BAZ_03725 ENOG4106F1P AAA ATPase, central domain protein BAZ_03731 ENOG41069ER domain protein BAZ_03732 ENOG4105DM4 PTS System BAZ_03733 ENOG4105DE4 1-phosphofructokinase BAZ_03734 ENOG4105E98 transcriptional regulator DeoR family BAZ_03735 ENOG4107QW4 alcohol dehydrogenase BAZ_03736 ENOG4107QW4 alcohol dehydrogenase BAZ_03737 ENOG4108SJC Membrane BAZ_03740 ENOG4105C85 amino acid BAZ_03744 ENOG4105TMB Formate nitrite transporter BAZ_03745 ENOG4105K70 DNA-binding protein BAZ_03746 ENOG4105C59 p-type ATPase BAZ_03747 ENOG4105C59 p-type ATPase BAZ_03748 ENOG410681U heavy metal transport detoxification protein BAZ_03749 ENOG4105VPX protein, conserved in bacteria BAZ_03751 ENOG4105NIV Esterase BAZ_03752 ENOG4105E0A ABC, transporter BAZ_03757 ENOG4105CGK Exodeoxyribonuclease III BAZ_03759 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAZ_03760 ENOG4105D03 DNA-3-methyladenine glycosylase II BAZ_03766 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_03768 ENOG4105BZU Histidine kinase BAZ_03771 ENOG41067MG lrgb family BAZ_03774 ENOG4107TTQ Alpha beta hydrolase fold BAZ_03775 ENOG4107YEI lmbE family BAZ_03780 ENOG4105F0V Cell wall hydrolase BAZ_03781 ENOG4107R6R udp-galactopyranose mutase BAZ_03782 ENOG4105E0M Sulfatase BAZ_03783 ENOG410890F Dynamin family BAZ_03785 ENOG4107QHE Choloylglycine hydrolase BAZ_03790 ENOG4105DA5 (ABC) transporter BAZ_03795 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAZ_03796 ENOG4105DQU oxidoreductase, subunit beta BAZ_03797 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BAZ_03798 ENOG4108IGT Dipeptidase BAZ_03799 ENOG4105MCT stage V sporulation protein S BAZ_03800 ENOG4105D48 metallophosphoesterase BAZ_03805 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAZ_03808 ENOG4105XZV Protein of unknown function (DUF3243) BAZ_03809 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAZ_03813 ENOG4105UIB (ABC) transporter BAZ_03814 ENOG4105UIB (ABC) transporter BAZ_03815 ENOG4108JQ9 ABC transporter BAZ_03816 ENOG4105DIH basic membrane BAZ_03817 ENOG4105FDP GntR family transcriptional regulator BAZ_03818 ENOG4107QZI cell division protein FtsK BAZ_03820 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAZ_03822 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAZ_03824 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAZ_03825 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAZ_03826 ENOG4105E35 Dipicolinate synthase subunit A BAZ_03828 ENOG4105C1V Peptidase, M16 BAZ_03832 ENOG4105DTN riboflavin biosynthesis protein ribF BAZ_03833 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAZ_03835 ENOG4105W7A Protein of unknown function (DUF503) BAZ_03837 ENOG4105VHM ribosomal protein BAZ_03838 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAZ_03839 ENOG4105CHV Transcription elongation factor NusA BAZ_03841 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAZ_03843 ENOG4105DZP Membrane-associated zinc metalloprotease BAZ_03844 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAZ_03845 ENOG4105KNE Phosphatidate cytidylyltransferase BAZ_03846 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAZ_03854 ENOG4108HE4 integrase family BAZ_03856 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAZ_03858 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAZ_03861 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAZ_03866 ENOG4105VB6 UPF0109 protein BAZ_03870 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAZ_03871 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAZ_03874 ENOG4105CHR reductase BAZ_03875 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAZ_03878 ENOG4105CB5 ATP-dependent DNA helicase recG BAZ_03879 ENOG4105DP4 dak2 domain fusion protein ylov BAZ_03880 ENOG4108ZAA Alkaline-shock protein BAZ_03882 ENOG4105FJ0 thiamine BAZ_03883 ENOG4105DJV ribulose-phosphate 3-epimerase BAZ_03884 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAZ_03885 ENOG4105D9P serine threonine protein kinase BAZ_03886 ENOG4108ZF3 Phosphatase BAZ_03888 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAZ_03890 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAZ_03891 ENOG4105C25 Primosomal protein n' BAZ_03892 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAZ_03896 ENOG4105DSJ YicC domain protein BAZ_03898 ENOG4105F23 Fibronectin-binding protein BAZ_03899 ENOG4105DC7 peptidase M24 BAZ_03910 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAZ_03915 ENOG4105C34 Pseudouridine synthase BAZ_03918 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAZ_03920 ENOG4105DBK s4 domain protein BAZ_03921 ENOG41067XK integral membrane protein BAZ_03923 ENOG4105DFA alanine racemase domain protein BAZ_03924 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAZ_03925 ENOG4105WR5 sporulation protein, YlmC YmxH family BAZ_03927 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_03929 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAZ_03930 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAZ_03931 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAZ_03932 ENOG4105D4A Cell wall formation (By similarity) BAZ_03933 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAZ_03934 ENOG4105CNI cell division protein FtsW BAZ_03937 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAZ_03938 ENOG4105CJN penicillin-binding protein BAZ_03939 ENOG4105CJN penicillin-binding protein BAZ_03940 ENOG41068DC Essential cell division protein (By similarity) BAZ_03947 ENOG4105KNH Nucleic acid-binding protein BAZ_03957 ENOG4105XSJ toxin secretion phage lysis holin BAZ_03974 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAZ_03976 ENOG4105CAR Terminase, large subunit BAZ_03993 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAZ_03996 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_04007 ENOG4108IMY Transcriptional regulator BAZ_04015 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAZ_04017 ENOG41063PX domain protein BAZ_04018 ENOG4105D78 K07001 NTE family protein BAZ_04019 ENOG4105H20 Sporulation integral membrane protein YlbJ BAZ_04021 ENOG4106H78 methyltransferase BAZ_04026 ENOG4107TB6 phosphoglycerate mutase BAZ_04029 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAZ_04039 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAZ_04040 ENOG4105CNI cell division protein FtsW BAZ_04043 ENOG4108IAB Phoh family BAZ_04047 ENOG4105QA2 BAZ_04048 ENOG4105CI3 gtp-binding protein typa BAZ_04050 ENOG4105ECY inositol monophosphatase BAZ_04054 ENOG4105CXN decarboxylase BAZ_04063 ENOG4105C7S Dehydrogenase BAZ_04064 ENOG4105CPP Dehydrogenase, E1 component BAZ_04067 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAZ_04068 ENOG4108X4Q Hydrolase BAZ_04070 ENOG4105CN5 Metallo-Beta-Lactamase BAZ_04071 ENOG4107ZYR domain protein BAZ_04078 ENOG4108XRC Protein of unknown function (DUF458) BAZ_04080 ENOG4107IN1 Protein of unknown function (DUF1797) BAZ_04083 ENOG4105EPM Diguanylate phosphodiesterase BAZ_04084 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAZ_04087 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BAZ_04089 ENOG4105UIN BAZ_04100 ENOG4108HGU Histidine kinase BAZ_04102 ENOG4105CHM Aminotransferase BAZ_04103 ENOG4105FKQ transcriptional regulator BAZ_04104 ENOG4105EG2 ABC transporter, permease BAZ_04106 ENOG4107FKK extracellular solute-binding protein family 1 BAZ_04108 ENOG4105CG3 alpha amylase, catalytic region BAZ_04117 ENOG4105CHU acetyl-coa acetyltransferase BAZ_04124 ENOG4105K7K Transcriptional regulator BAZ_04125 ENOG4105DTD Dehydrogenase BAZ_04127 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAZ_04129 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAZ_04134 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAZ_04137 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAZ_04138 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAZ_04139 ENOG4106TD9 Diguanylate cyclase BAZ_04143 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAZ_04146 ENOG4105CID antiterminator BAZ_04148 ENOG4105FDP GntR family transcriptional regulator BAZ_04150 ENOG4105CE4 GlcNAc 6-P deacetylase BAZ_04157 ENOG4107ZE5 PPIases accelerate the folding of proteins BAZ_04158 ENOG4105PTM secreted protein BAZ_04159 ENOG4105J7I hydrolase BAZ_04161 ENOG4105G6R Stage v sporulation protein ae BAZ_04163 ENOG4105CZ3 stage V sporulation protein ad BAZ_04164 ENOG41090VF Stage v sporulation protein ac BAZ_04168 ENOG4105C8J )-transporter BAZ_04169 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_04171 ENOG41082AN stage II sporulation protein BAZ_04172 ENOG4105DZ1 carboxypeptidase BAZ_04173 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAZ_04174 ENOG4105DVE abc transporter atp-binding protein BAZ_04180 ENOG4105D7N magnesium and cobalt transport protein CorA BAZ_04185 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAZ_04187 ENOG4105I3K Ferric uptake regulator, Fur family BAZ_04188 ENOG4105MZ9 stage II sporulation protein m BAZ_04192 ENOG4105CPC Aldo Keto reductase BAZ_04194 ENOG4105RHY Pfam:UPF0157 BAZ_04198 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAZ_04200 ENOG4105ETE Transcriptional regulator (LacI family BAZ_04201 ENOG4108YM7 Gcn5-related n-acetyltransferase BAZ_04205 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAZ_04206 ENOG4108R6K riboflavin synthase, subunit alpha BAZ_04210 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAZ_04211 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAZ_04212 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAZ_04213 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAZ_04215 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAZ_04217 ENOG4105DFD Na H antiporter BAZ_04218 ENOG4105CGH 5'-nucleotidase BAZ_04226 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BAZ_04229 ENOG4108IXY short-chain dehydrogenase reductase BAZ_04230 ENOG41069FQ Metallo-beta-lactamase superfamily BAZ_04232 ENOG4105II7 pyrroline-5-carboxylate reductase BAZ_04233 ENOG4105EJQ L-serine dehydratase BAZ_04237 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAZ_04238 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAZ_04240 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAZ_04241 ENOG4105D9U N-acetyltransferase BAZ_04243 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAZ_04244 ENOG4108QEG Membrane BAZ_04245 ENOG4105CDA abc transporter atp-binding protein BAZ_04246 ENOG4105E5Q amino acid AbC transporter BAZ_04247 ENOG4108HW3 (ABC) transporter BAZ_04249 ENOG4105G7B Protein of unknown function (DUF2992) BAZ_04250 ENOG4105E09 nadh pyrophosphatase BAZ_04252 ENOG4105C7S Dehydrogenase BAZ_04253 ENOG4105CPP Dehydrogenase, E1 component BAZ_04257 ENOG4107RDP Dehydrogenase BAZ_04259 ENOG4108JUB Transcriptional regulator BAZ_04261 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAZ_04264 ENOG4107QQR Sporulation BAZ_04265 ENOG4105S1Z Stage IV sporulation protein B BAZ_04266 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAZ_04268 ENOG4105DX0 Hemolysin A BAZ_04270 ENOG4105CTB Polyprenyl synthetase BAZ_04275 ENOG4108ZSR alkaline shock protein BAZ_04276 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAZ_04281 ENOG410644B Stage III sporulation protein af BAZ_04283 ENOG4105KQ4 Stage iii sporulation protein ad BAZ_04284 ENOG4108CQH stage III sporulation protein AC BAZ_04285 ENOG4105KR5 Stage iii sporulation protein BAZ_04286 ENOG4105CD2 stage iii sporulation protein aa BAZ_04291 ENOG4105DC7 peptidase M24 BAZ_04294 ENOG4105CBJ Metal-dependent enzyme BAZ_04296 ENOG4107YBY Hydrolase BAZ_04300 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAZ_04301 ENOG4105WZW rhodanese family BAZ_04305 ENOG41080TC multidrug resistance protein BAZ_04312 ENOG4105CJ1 ABC, transporter BAZ_04313 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAZ_04319 ENOG4105C0D helicase BAZ_04343 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAZ_04344 ENOG4105C3R Methionine synthase BAZ_04346 ENOG4105C28 cystathionine BAZ_04347 ENOG4105C28 cystathionine BAZ_04351 ENOG4105C5X domain protein BAZ_04353 ENOG4105DKQ ROK family BAZ_04355 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAZ_04358 ENOG4108UTW Plays a role in the regulation of phosphate uptake BAZ_04359 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAZ_04360 ENOG4105E2Z phosphate ABC transporter (Permease BAZ_04361 ENOG4105C8U phosphate abc transporter BAZ_04362 ENOG4105PWN phosphate abc transporter BAZ_04363 ENOG4107RF6 penicillin-binding protein BAZ_04365 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAZ_04370 ENOG4105N80 Ferric uptake regulator, Fur family BAZ_04372 ENOG4105FDK ABC transporter BAZ_04373 ENOG4108JYZ YitT family BAZ_04374 ENOG41069ZM Protein of unknown function (DUF2624) BAZ_04379 ENOG4105EGD dinuclear metal center protein, YbgI family BAZ_04382 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_04383 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAZ_04388 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAZ_04389 ENOG4105KG3 cytidine deaminase BAZ_04390 ENOG4107YR5 Diacylglycerol kinase BAZ_04392 ENOG4105CTJ Metal Dependent Phosphohydrolase BAZ_04393 ENOG4105C9A Phoh family BAZ_04395 ENOG41068P3 sporulation protein YqfC BAZ_04396 ENOG4105KTH gatB Yqey BAZ_04398 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAZ_04399 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAZ_04403 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAZ_04405 ENOG4105CSA Coproporphyrinogen iii oxidase BAZ_04406 ENOG4105KVH Transcriptional regulator BAZ_04411 ENOG4105TQK DNA polymerase iii, delta' subunit BAZ_04413 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAZ_04414 ENOG4108UK2 deaminase BAZ_04415 ENOG4105KQC Competence protein BAZ_04417 ENOG4105DXX methyltransferase BAZ_04419 ENOG4108WF2 Metal Dependent Phosphohydrolase BAZ_04421 ENOG410812S Rna-binding protein BAZ_04423 ENOG4105CQW ribosome biogenesis GTPase YqeH BAZ_04424 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAZ_04426 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_04431 ENOG4108TVJ Nitroreductase BAZ_04434 ENOG4105G6Z alkaline phosphatase BAZ_04436 ENOG4108MUZ hydrolase BAZ_04443 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAZ_04444 ENOG4105MIR Phenylalanine 4-monooxygenase BAZ_04446 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_04447 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_04455 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAZ_04456 ENOG4108V5C ABC transporter BAZ_04458 ENOG4108EKI Dehydrogenase BAZ_04459 ENOG4105C28 cystathionine BAZ_04465 ENOG4107XRG penicillin-binding protein BAZ_04468 ENOG4105CFP Peptidase U32 BAZ_04469 ENOG4105XYU peptidase (U32 family) BAZ_04470 ENOG4108VQJ O-methyltransferase BAZ_04471 ENOG4105HHA aminodeoxychorismate lyase BAZ_04475 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAZ_04477 ENOG4105C02 permease BAZ_04480 ENOG41060CR BAZ_04481 ENOG4105C7H Helicase, RecD TraA family BAZ_04483 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAZ_04484 ENOG4105C3J Cysteine desulfurase BAZ_04486 ENOG4105D1H recombination factor protein RarA BAZ_04487 ENOG4108VCI transcription factor, rsfa family BAZ_04488 ENOG4105CUZ uba thif-type nad fad binding protein BAZ_04490 ENOG4105CUT histidyl-tRNA synthetase BAZ_04493 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAZ_04495 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAZ_04496 ENOG41076HS cation diffusion facilitator family transporter BAZ_04497 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAZ_04499 ENOG4105CKP Polysaccharide Biosynthesis Protein BAZ_04500 ENOG4108QG2 Membrane BAZ_04502 ENOG4105VIE preprotein translocase, subunit YajC BAZ_04505 ENOG41061AI Protein of unknown function (DUF2905) BAZ_04508 ENOG4108HUF Transporter BAZ_04510 ENOG4108IPJ Membrane BAZ_04511 ENOG4108IPJ Membrane BAZ_04512 ENOG41082BM Transcriptional regulator, arsr family BAZ_04517 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAZ_04518 ENOG4108IYU L-aspartate oxidase BAZ_04521 ENOG4108RPX mosc domain containing protein BAZ_04522 ENOG4105CQC Prephenate dehydratase BAZ_04526 ENOG4105EWM Histidine kinase BAZ_04529 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAZ_04532 ENOG4105X36 (ribosomal) protein BAZ_04534 ENOG4105C03 ribonuclease BAZ_04537 ENOG4107QMS site-determining protein BAZ_04540 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAZ_04541 ENOG4105DFF Rod shape-determining protein mreb BAZ_04545 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAZ_04546 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAZ_04548 ENOG41068KH stage VI sporulation protein D BAZ_04550 ENOG4105D52 delta-aminolevulinic acid dehydratase BAZ_04555 ENOG4105K56 Transcriptional regulator BAZ_04559 ENOG4108IUQ atp-dependent protease BAZ_04565 ENOG4108QCI YvbH-like oligomerisation region BAZ_04569 ENOG4105M59 Phosphodiesterase, mj0936 family BAZ_04570 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAZ_04572 ENOG4108XJQ germination protein BAZ_04574 ENOG4108PCX Major Facilitator BAZ_04576 ENOG4105KBX Transcriptional regulator, TetR family BAZ_04579 ENOG4105PFC Transcriptional regulator BAZ_04582 ENOG4105DZC cytosine deaminase BAZ_04583 ENOG4105DZC cytosine deaminase BAZ_04584 ENOG4105DEF Extracellular solute-binding protein, family 5 BAZ_04585 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAZ_04588 ENOG4108JQ7 (ABC) transporter BAZ_04589 ENOG4108HRK Histidine kinase BAZ_04590 ENOG4105DY9 regulatoR BAZ_04593 ENOG41067S9 phage shock protein C, PspC BAZ_04594 ENOG4108JCI Transcriptional regulator BAZ_04596 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BAZ_04597 ENOG4108Z40 Transcriptional regulator BAZ_04598 ENOG4105RHA ABC transporter, permease BAZ_04599 ENOG4108IUX (ABC) transporter BAZ_04600 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BAZ_04601 ENOG4105ER2 Ompa motb domain protein BAZ_04602 ENOG4105ER2 Ompa motb domain protein BAZ_04603 ENOG4105E14 MotA TolQ exbB proton channel BAZ_04604 ENOG4108VXD carboxy-peptidase BAZ_04606 ENOG4105E33 succinate dehydrogenase BAZ_04608 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAZ_04611 ENOG4105K63 Thioredoxin BAZ_04612 ENOG4105C10 Electron transfer flavoprotein BAZ_04613 ENOG4105BZJ Electron transfer flavoprotein BAZ_04614 ENOG41060WC Enoyl-CoA hydratase BAZ_04615 ENOG4107Z3H Transcriptional regulator, TetR family BAZ_04616 ENOG4105CEY Amp-dependent synthetase and ligase BAZ_04618 ENOG4105J76 Periplasmic binding protein BAZ_04619 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAZ_04628 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAZ_04631 ENOG4105DR4 Methyltransferase BAZ_04634 ENOG4105KFN sortase, SrtB family BAZ_04635 ENOG4105E0A ABC, transporter BAZ_04638 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BAZ_04640 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BAZ_04642 ENOG4105FE9 pseudouridine synthase BAZ_04645 ENOG4105DCG PHP domain protein BAZ_04652 ENOG4105C5S asparaginyl-tRNA synthetase BAZ_04653 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAZ_04655 ENOG4108RWN rrna methyltransferase BAZ_04662 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAZ_04663 ENOG4105CW7 secretion protein, HlyD family BAZ_04664 ENOG4108JGH Tetr family transcriptional regulator BAZ_04665 ENOG4105CN9 Peptidase m42 family protein BAZ_04669 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAZ_04670 ENOG4105C22 threonyL-tRNA synthetase BAZ_04671 ENOG4108TDW sporulation protein YtxC BAZ_04675 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAZ_04676 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAZ_04677 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAZ_04679 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAZ_04680 ENOG4105C2M dna polymerase I BAZ_04681 ENOG4105BZU Histidine kinase BAZ_04682 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAZ_04686 ENOG4108HMX isocitrate dehydrogenase (NADP) BAZ_04687 ENOG4105BZN citrate synthase BAZ_04689 ENOG4108REF Sporulation integral membrane protein ytvi BAZ_04690 ENOG4105FS0 cytoplasmic membrane protein BAZ_04695 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAZ_04696 ENOG4105C6K Malic enzyme BAZ_04697 ENOG4105C0B DNA polymerase III (alpha subunit) BAZ_04698 ENOG4105VV2 BAZ_04700 ENOG4105SFS phosphoesterase RecJ domain protein BAZ_04707 ENOG4105DC7 peptidase M24 BAZ_04714 ENOG4105Z7P Acetyltransferase (GNAT) family BAZ_04715 ENOG41082W1 Cupin 2, conserved barrel domain protein BAZ_04717 ENOG4105VZ8 Transcriptional regulator BAZ_04721 ENOG4107YZX Universal stress protein BAZ_04730 ENOG4108JYZ YitT family BAZ_04734 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAZ_04736 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAZ_04737 ENOG4105KBJ sporulation protein ytfj BAZ_04740 ENOG4105EFZ amidohydrolase BAZ_04742 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAZ_04747 ENOG4106KR7 LysR family Transcriptional regulator BAZ_04749 ENOG4105U5Y Transcriptional regulator BAZ_04750 ENOG4105U5Y Transcriptional regulator BAZ_04752 ENOG4105C28 cystathionine BAZ_04756 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAZ_04758 ENOG4105EMN RNA polymerase sigma factor BAZ_04761 ENOG4105F1V Acetoin utilization protein BAZ_04762 ENOG4105W87 Cbs domain BAZ_04763 ENOG4105DGU Histone deacetylase BAZ_04765 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAZ_04767 ENOG4107SNB ankyrin repeat protein YahD BAZ_04768 ENOG4105EP9 oxidoreductase BAZ_04774 ENOG4105ETE Transcriptional regulator (LacI family BAZ_04778 ENOG4105C88 aminopeptidase BAZ_04787 ENOG4108VDD TRNA binding domain protein BAZ_04793 ENOG4105C8F Beta-lactamase domain protein BAZ_04796 ENOG4108V15 phosphotransferase enzyme family BAZ_04797 ENOG4108IUM Glycogen debranching enzyme BAZ_04799 ENOG4107QSE Dipeptidase BAZ_04800 ENOG4107QSE Dipeptidase BAZ_04801 ENOG4105YW5 deoR family transcriptional regulator BAZ_04804 ENOG4105CBX hi0933 family BAZ_04811 ENOG4108VJ1 Transcriptional regulator (CarD family BAZ_04812 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BAZ_04813 ENOG4105CSC Glucose uptake protein BAZ_04816 ENOG4108ZAF Molybdopterin BAZ_04817 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAZ_04818 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAZ_04820 ENOG4105D06 uba thif-type nad fad binding protein BAZ_04821 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAZ_04825 ENOG41085GJ domain protein BAZ_04827 ENOG4105DWV Homoserine O-trans-acetylase BAZ_04829 ENOG4108B31 Spore germination protein BAZ_04835 ENOG410605W Major Facilitator BAZ_04836 ENOG4107S91 Sodium hydrogen exchanger BAZ_04837 ENOG4105NCW Trka-c domain protein BAZ_04840 ENOG4105C19 ABC transporter BAZ_04844 ENOG4105N5T Radical SAM Protein BAZ_04846 ENOG4105DA5 (ABC) transporter BAZ_04852 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAZ_04853 ENOG4108Z0R Transferase BAZ_04854 ENOG4105YVM Phosphoesterase, PA-phosphatase related BAZ_04855 ENOG4105BZF Glycosyl transferase (Group 1 BAZ_04857 ENOG4108RIR Molybdenum cofactor biosynthesis protein BAZ_04867 ENOG4105EGD dinuclear metal center protein, YbgI family BAZ_04868 ENOG4105BZU Histidine kinase BAZ_04869 ENOG4105BZU Histidine kinase BAZ_04870 ENOG4107S9D Alpha beta hydrolase BAZ_04871 ENOG4107T7U Sulfatase BAZ_04875 ENOG4105D2X ABC transporter substrate-binding protein BAZ_04877 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAZ_04881 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAZ_04889 ENOG4108V2W Carbonate dehydratase BAZ_04890 ENOG4105C4M (Ubiquinol oxidase) subunit I BAZ_04891 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAZ_04900 ENOG41087YS Phage shock protein A BAZ_04907 ENOG4105BZU Histidine kinase BAZ_04909 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_04914 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAZ_04915 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAZ_04922 ENOG4107ZTW SNARE associated Golgi BAZ_04925 ENOG4105C19 ABC transporter BAZ_04926 ENOG41086D8 Transcriptional regulator BAZ_04937 ENOG4105C6Z Gluconate BAZ_04938 ENOG4105FDP GntR family transcriptional regulator BAZ_04942 ENOG41069H0 dihydroorotase EC 3.5.2.3 BAZ_04948 ENOG4105DTQ mandelate racemase muconate lactonizing BAZ_04950 ENOG4108IPT Naphthoate synthase BAZ_04951 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAZ_04952 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAZ_04953 ENOG4105E4F Isochorismate synthase BAZ_04954 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAZ_04956 ENOG4105VEQ Cold shock protein BAZ_04961 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BAZ_04963 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BAZ_04965 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAZ_04984 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BAZ_04991 ENOG4105KT7 mgtC SapB transporter BAZ_04992 ENOG4107PBV potassium channel BAZ_04994 ENOG4107QYV phosphohexose isomerase BAZ_04995 ENOG4105WG9 Conserved Protein BAZ_04997 ENOG4105CHM Aminotransferase BAZ_04998 ENOG4108ZB6 transcriptional regulator AsnC family BAZ_04999 ENOG4105C5I Dehydrogenase BAZ_05000 ENOG4108MUZ hydrolase BAZ_05002 ENOG4105C87 Aminotransferase class I and II BAZ_05005 ENOG4105Y38 Kinase-associated protein B BAZ_05007 ENOG4107R3E Citrate transporter BAZ_05010 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BAZ_05011 ENOG4105KA0 thioesterase Superfamily protein BAZ_05015 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAZ_05019 ENOG41069ER domain protein BAZ_05022 ENOG4105CEP NADH dehydrogenase BAZ_05028 ENOG4105EWC Purine nucleoside phosphorylase BAZ_05031 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAZ_05035 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAZ_05036 ENOG4105C4B ABC transporter, permease BAZ_05037 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BAZ_05046 ENOG41083MR nifu domain-containing protein BAZ_05049 ENOG4108W5N phosphatidylglycerophosphatase a BAZ_05051 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAZ_05052 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAZ_05055 ENOG4105CBT Fructose-1,6-bisphosphatase BAZ_05058 ENOG4105MMD transcriptional regulator BAZ_05059 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BAZ_05060 ENOG4107TXC Transcriptional regulator BAZ_05061 ENOG41090T1 Membrane BAZ_05066 ENOG4105FAA peptidase M23 BAZ_05068 ENOG4105KZD Domain of unknown function (DUF1805) BAZ_05069 ENOG4107R8B 5'-nucleotidase BAZ_05072 ENOG4105DIW FeS assembly protein SUFB BAZ_05073 ENOG4108UNV SUF system FeS assembly protein, NifU family BAZ_05074 ENOG4105C9B Cysteine desulfurase BAZ_05075 ENOG4105JRK feS assembly protein SufD BAZ_05076 ENOG4105C3K feS assembly ATPase SufC BAZ_05077 ENOG4105D01 (LipO)protein BAZ_05078 ENOG4105D01 (LipO)protein BAZ_05079 ENOG4108UMI ABC transporter, permease BAZ_05085 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAZ_05094 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAZ_05100 ENOG4108W8B Beta-lactamase domain protein BAZ_05101 ENOG4105C1G acyl-Coa dehydrogenase BAZ_05102 ENOG4105CHU acetyl-coa acetyltransferase BAZ_05105 ENOG4105DZ1 carboxypeptidase BAZ_05109 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAZ_05113 ENOG4108SUT Major Facilitator Superfamily BAZ_05114 ENOG4107R7I amino acid BAZ_05116 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAZ_05118 ENOG4107AYK membrAne BAZ_05125 ENOG4107ZTW SNARE associated Golgi BAZ_05127 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BAZ_05128 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_05129 ENOG4105BZU Histidine kinase BAZ_05131 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAZ_05134 ENOG4105VG1 fes assembly suf system protein BAZ_05135 ENOG4105D4Y metalloprotease BAZ_05139 ENOG4107S91 Sodium hydrogen exchanger BAZ_05140 ENOG4105NCW Trka-c domain protein BAZ_05142 ENOG4108RMU ferritin dps family protein BAZ_05145 ENOG4108URH decarboxylase BAZ_05150 ENOG4105D9N nucleoside BAZ_05151 ENOG4105D9N nucleoside BAZ_05154 ENOG4108RYK Nad-dependent epimerase dehydratase BAZ_05159 ENOG4105CV8 reductase BAZ_05160 ENOG4105F27 Major Facilitator BAZ_05161 ENOG4105KVH Transcriptional regulator BAZ_05164 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAZ_05165 ENOG4105D4A Cell wall formation (By similarity) BAZ_05167 ENOG4105C8Q Methyl-accepting chemotaxis BAZ_05169 ENOG4105WMR Protein CrcB homolog BAZ_05170 ENOG4105WMR Protein CrcB homolog BAZ_05173 ENOG4108MK9 spermidine N(1)-acetyltransferase BAZ_05174 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BAZ_05177 ENOG4108IPW abc transporter atp-binding protein BAZ_05178 ENOG4105CM4 permease protein BAZ_05184 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAZ_05186 ENOG4105XZU Preprotein translocase, subunit SecG BAZ_05187 ENOG41067MG lrgb family BAZ_05207 ENOG4105EFC phage portal protein HK97 family BAZ_05212 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAZ_05214 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAZ_05215 ENOG4105CP7 Triose-phosphate isomerase BAZ_05220 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_05224 ENOG41090VF Stage v sporulation protein ac BAZ_05225 ENOG4105CZ3 stage V sporulation protein ad BAZ_05228 ENOG4105H67 Protein of unknown function (DUF421) BAZ_05229 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAZ_05230 ENOG4105KRI phosphocarrier protein (HPr BAZ_05232 ENOG4105CHW UPF0052 protein BAZ_05234 ENOG4108Z4K mutator MutT protein BAZ_05236 ENOG4105C3M thioredoxin reductase BAZ_05238 ENOG4108S4C acetyltransferase BAZ_05242 ENOG41086DT Membrane protein of unknown function BAZ_05244 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAZ_05245 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAZ_05246 ENOG4105D7V transposase BAZ_05249 ENOG4107TXC Transcriptional regulator BAZ_05253 ENOG4105HMI Membrane BAZ_05254 ENOG4105DUM transcriptional regulator, lysR family BAZ_05256 ENOG4108WS4 fmn reductase BAZ_05259 ENOG4105BZ1 (ABC) transporter BAZ_05261 ENOG4105CN1 protease BAZ_05262 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAZ_05263 ENOG4105CAK Cell division ATP-binding protein ftsE BAZ_05265 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BAZ_05266 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAZ_05267 ENOG4105MS2 ribosomal subunit Interface protein BAZ_05268 ENOG4105VEQ Cold shock protein BAZ_05269 ENOG41081UC Inherit from COG: Competence protein BAZ_05272 ENOG4105KVH Transcriptional regulator BAZ_05274 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAZ_05275 ENOG4108KGH TRANSCRIPTIONal BAZ_05276 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAZ_05277 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAZ_05278 ENOG4105ESV Glycosyl transferase, family 4 BAZ_05280 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAZ_05283 ENOG410901P UPF0249 protein BAZ_05284 ENOG4105F8D glycoside hydrolase family 4 BAZ_05285 ENOG4105VCP PTS System BAZ_05286 ENOG4105CK1 PTS System BAZ_05288 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAZ_05289 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAZ_05290 ENOG4105VCP PTS System BAZ_05292 ENOG4105VZJ PTS System BAZ_05295 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BAZ_05296 ENOG4105ECB domain protein BAZ_05297 ENOG4107RSM transcriptional regulator BAZ_05305 ENOG4105DAA L-lactate BAZ_05307 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BAZ_05309 ENOG4105E0M Sulfatase BAZ_05315 ENOG4107R8N Glycosyl transferase, family 2 BAZ_05317 ENOG4105C94 Transporter BAZ_05318 ENOG41069ER domain protein BAZ_05323 ENOG4105KBK Zinc finger, swim domain protein BAZ_05324 ENOG4105C0D helicase BAZ_05330 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAZ_05332 ENOG4107RBB ABC transporter, permease BAZ_05333 ENOG4105C19 ABC transporter BAZ_05337 ENOG4105CXY transporter BAZ_05340 ENOG4105BZU Histidine kinase BAZ_05341 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_05342 ENOG4105CMR udp-glucose 4-epimerase BAZ_05345 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAZ_05346 ENOG4105EY8 ABC transporter BAZ_05356 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAZ_05358 ENOG4105FRN stage II sporulation protein BAZ_05361 ENOG4105DY9 regulatoR BAZ_05362 ENOG4108IUW ABC transporter BAZ_05366 ENOG4106778 Protein of unknown function (DUF1146) BAZ_05367 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAZ_05368 ENOG4105C8S subunit m BAZ_05369 ENOG4105D65 subunit l BAZ_05374 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAZ_05375 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAZ_05377 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAZ_05378 ENOG4105BZU Histidine kinase BAZ_05388 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAZ_05389 ENOG41062M3 atp synthase BAZ_05394 ENOG4108YZG isomerase BAZ_05397 ENOG4108VGI doxx family BAZ_05398 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAZ_05401 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAZ_05403 ENOG4108ZXQ stage ii sporulation protein r BAZ_05404 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAZ_05405 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAZ_05408 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAZ_05409 ENOG4105CBT Fructose-1,6-bisphosphatase BAZ_05410 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAZ_05417 ENOG4105C1G acyl-Coa dehydrogenase BAZ_05418 ENOG4105C1G acyl-Coa dehydrogenase BAZ_05419 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAZ_05421 ENOG4105DF6 Fe-S oxidoreductase BAZ_05424 ENOG4105BZU Histidine kinase BAZ_05429 ENOG4105BZU Histidine kinase BAZ_05430 ENOG4105KCT ABC transporter BAZ_05431 ENOG4108M15 ABC transporter BAZ_05432 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAZ_05436 ENOG4105IIU Aminopeptidase BAZ_05440 ENOG4105EMN RNA polymerase sigma factor BAZ_05442 ENOG410684U Domain of unknown function (DUF1934) BAZ_05446 ENOG4105CYW agmatinase BAZ_05448 ENOG4105DXB Major Facilitator superfamily BAZ_05449 ENOG4107SWG transcriptional regulator MERR family BAZ_05450 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAZ_05451 ENOG4105BZ4 penicillin-binding protein BAZ_05452 ENOG4108XFG YwhD family BAZ_05453 ENOG4108Z4T Peptidase M50 BAZ_05454 ENOG41069HH 4-oxalocrotonate tautomerase BAZ_05455 ENOG4105DCI Phosphohydrolase BAZ_05456 ENOG4108MES Periplasmic binding protein BAZ_05457 ENOG4105E0A ABC, transporter BAZ_05458 ENOG4105EHG Permease protein BAZ_05459 ENOG4105DQ5 transport system permease protein BAZ_05460 ENOG4105DQ5 transport system permease protein BAZ_05462 ENOG4108VCI transcription factor, rsfa family BAZ_05465 ENOG4108IJ2 phosphate acetyltransferase BAZ_05468 ENOG4108VKI Cell wall hydrolase BAZ_05472 ENOG4107SVH Potassium channel protein BAZ_05474 ENOG410667J hydrolase BAZ_05475 ENOG4105VCH membrane BAZ_05477 ENOG4108TU7 Inherit from COG: (ABC) transporter BAZ_05478 ENOG4105CJ1 ABC, transporter BAZ_05479 ENOG41090WU lipolytic protein G-D-S-L family BAZ_05482 ENOG4105D6E homoserine dehydrogenase BAZ_05488 ENOG4108Y4K DNA-binding transcriptional activator BAZ_05490 ENOG4105WH1 Two component transcriptional regulator luxr family BAZ_05491 ENOG4105BZU Histidine kinase BAZ_05492 ENOG4105BZU Histidine kinase BAZ_05493 ENOG4105DWF phosphomethylpyrimidine kinase BAZ_05494 ENOG4105BZU Histidine kinase BAZ_05495 ENOG4105VCD cytoplasmic protein BAZ_05496 ENOG4105D22 carbon starvation protein BAZ_05497 ENOG4105DY9 regulatoR BAZ_05498 ENOG41079KZ Major Facilitator Superfamily BAZ_05502 ENOG4105EN6 Membrane BAZ_05503 ENOG4106YBV Methyl-accepting chemotaxis BAZ_05505 ENOG4108S4H thioesterase Superfamily protein BAZ_05507 ENOG4105JEU Glycosyl transferase, family 2 BAZ_05508 ENOG4105C5H ABC transporter BAZ_05513 ENOG4105CKK Glycosyl transferase, family 2 BAZ_05514 ENOG41067SE Tetr family transcriptional regulator BAZ_05516 ENOG4105E0X reductase BAZ_05517 ENOG4106F5Q Membrane BAZ_05520 ENOG4105DY9 regulatoR BAZ_05521 ENOG4108HRK Histidine kinase BAZ_05522 ENOG4107RGD Major Facilitator superfamily BAZ_05525 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAZ_05527 ENOG4105IW1 AmiS UreI transporter BAZ_05529 ENOG4105CMR udp-glucose 4-epimerase BAZ_05530 ENOG4108UT2 hemolysin iii BAZ_05532 ENOG4105C1J atp-dependent rna helicase BAZ_05536 ENOG4105DPN Oligoendopeptidase f BAZ_05540 ENOG4105C0H protease BAZ_05541 ENOG4105Q2H domain protein BAZ_05544 ENOG4105BZU Histidine kinase BAZ_05545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAZ_05551 ENOG4105CDU Replicative dna helicase BAZ_05553 ENOG4105BZR domain protein BAZ_05554 ENOG4108XMW Membrane BAZ_05556 ENOG4108UUM single-stranded DNA-binding protein BAZ_05558 ENOG4105C3G gtp-binding protein BAZ_05559 ENOG4105VDK protein, conserved in bacteria BAZ_05560 ENOG4105D8X mechanosensitive ion channel BAZ_05561 ENOG4108ZDA Sporulation protein YyaC BAZ_05562 ENOG4105FA0 parb-like partition protein BAZ_05563 ENOG4107QJE Chromosome Partitioning Protein BAZ_05567 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAZ_05569 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAZ_pXO1_00011 ENOG4105EKQ RNA-directed DNA polymerase BAZ_pXO1_00033 ENOG4105EKQ RNA-directed DNA polymerase BAZ_pXO1_00045 ENOG4106JUT Streptomycin 3''-adenylyltransferase BAZ_pXO1_00059 ENOG4105CNU cell division protein FtsK BAZ_pXO1_00108 ENOG4105DHF Membrane BAZ_pXO1_00114 ENOG4106AKK s-layer domain-containing protein BAZ_pXO1_00115 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAZ_pXO1_00118 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAZ_pXO1_00119 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAZ_pXO1_00120 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAZ_pXO1_00124 ENOG4105DQ6 Transposase BAZ_pXO1_00125 ENOG4105DQ6 Transposase BAZ_pXO1_00133 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BAZ_pXO1_00139 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAZ_pXO1_00161 ENOG4105KRN Transcriptional regulator, abrb family BAZ_pXO1_00163 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAZ_pXO1_00170 ENOG4108IBT Inherit from COG: transposase BAZ_pXO1_00172 ENOG4105DQ6 Transposase BAZ_pXO1_00173 ENOG4105DQ6 Transposase BAZ_pXO1_00176 ENOG4105DQ6 Transposase BAZ_pXO1_00179 ENOG4108MEK Metal-binding protein YodA BAZ_pXO1_00181 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BAZ_pXO1_00188 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAZ_pXO2-00006 ENOG4105K4H Nlp p60 protein BAZ_pXO2-00041 ENOG4107QJE Chromosome Partitioning Protein BAZ_pXO2-00046 ENOG4105DQ6 Transposase BAZ_pXO2-00052 ENOG4105EWC Purine nucleoside phosphorylase BAZ_pXO2-00071 ENOG4105C3F Signal peptidase i BAZ_pXO2-00078 ENOG4105N14 lysine exporter protein LysE YggA BAZ_pXO2-00084 ENOG4108J59 Extracellular solute-binding protein, family 5 BAZ_pXO2-00088 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAZ_pXO2-00099 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAZ_pXO2-00100 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)