locus-tag class description BACvac02_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BACvac02_0003 ENOG410848D S4 domain protein YaaA BACvac02_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BACvac02_0015 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BACvac02_0022 ENOG4105ZMH deoxynucleoside kinase BACvac02_0024 ENOG4105GTG Isochorismatase BACvac02_0025 ENOG4108Z6B deaminase BACvac02_0026 ENOG4105C6E dna polymerase iii BACvac02_0030 ENOG41067KS pro-sigma K processing BACvac02_0039 ENOG4105CXN decarboxylase BACvac02_0041 ENOG4105FA2 dna polymerase iii BACvac02_0042 ENOG4105MA4 psp1 domain protein BACvac02_0044 ENOG41060K3 Methyltransferase BACvac02_0046 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BACvac02_0047 ENOG4105KRN Transcriptional regulator, abrb family BACvac02_0049 ENOG4105F8V Hydrolase, tatD family BACvac02_0050 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BACvac02_0052 ENOG4105XFA sporulation peptidase YabG BACvac02_0054 ENOG4105W42 Veg protein BACvac02_0057 ENOG4105DFT pur operon repressor BACvac02_0058 ENOG4105KME endoribonuclease L-psp BACvac02_0061 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BACvac02_0062 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BACvac02_0064 ENOG4108JA2 transcriptioN-repair coupling factor BACvac02_0065 ENOG4108JA2 transcriptioN-repair coupling factor BACvac02_0066 ENOG4108M14 stage v sporulation protein t BACvac02_0068 ENOG4108IY2 MazG family BACvac02_0069 ENOG41082I2 s4 domain protein BACvac02_0070 ENOG4105VYY sporulation protein yabp BACvac02_0073 ENOG41060GV RNA binding s1 domain protein BACvac02_0077 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BACvac02_0078 ENOG4108UGV hypoxanthine phosphoribosyltransferase BACvac02_0079 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BACvac02_0082 ENOG4105C6T cysteine synthase BACvac02_0083 ENOG4105CRQ synthase (Component I) BACvac02_0084 ENOG4105DDQ anthranilate synthase BACvac02_0085 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BACvac02_0086 ENOG4105EEI dihydropteroate synthase BACvac02_0087 ENOG4105KRF dihydroneopterin aldolase BACvac02_0088 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BACvac02_0090 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BACvac02_0098 ENOG4108Z0C Uvrb UvrC protein BACvac02_0102 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BACvac02_0104 ENOG4105CTP PilT protein domain protein BACvac02_0108 ENOG4105D7W serine acetyltransferase BACvac02_0111 ENOG4105C2N RNA methyltransferase TrmH family group 3 BACvac02_0112 ENOG4105M0M Tetracycline resistance protein BACvac02_0113 ENOG4105QIV RNA polymerase BACvac02_0115 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BACvac02_0120 ENOG4107Y49 methyltransferase BACvac02_0122 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BACvac02_0123 ENOG4105XPM ribosomal protein BACvac02_0143 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BACvac02_0148 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BACvac02_0149 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BACvac02_0151 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BACvac02_0158 ENOG4108JJB ABC transporter BACvac02_0159 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BACvac02_0165 ENOG4105D1F ATP-binding protein BACvac02_0168 ENOG4108NMV polysaccharide deacetylase BACvac02_0187 ENOG4105C8B TIGR00159 family BACvac02_0188 ENOG4107U5W ybbr family BACvac02_0190 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BACvac02_0191 ENOG4108VQT Alpha beta hydrolase fold protein BACvac02_0193 ENOG4105CMG Carbohydrate kinase BACvac02_0194 ENOG4105CMG Carbohydrate kinase BACvac02_0196 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BACvac02_0197 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BACvac02_0204 ENOG4108PSK reductase BACvac02_0205 ENOG4108UMI ABC transporter, permease BACvac02_0206 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_0207 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_0208 ENOG4105D01 (LipO)protein BACvac02_0209 ENOG4105EE1 crotonyl-CoA reductase BACvac02_0211 ENOG4105IQ5 FAD linked oxidase domain protein BACvac02_0214 ENOG4105C2C drug resistance transporter, Bcr CflA BACvac02_0217 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BACvac02_0218 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACvac02_0219 ENOG4105C3U ABC transporter BACvac02_0220 ENOG4108JQ7 (ABC) transporter BACvac02_0226 ENOG4108J59 Extracellular solute-binding protein, family 5 BACvac02_0227 ENOG4108J59 Extracellular solute-binding protein, family 5 BACvac02_0229 ENOG4105II7 pyrroline-5-carboxylate reductase BACvac02_0230 ENOG4107XDY Nicotinamide Mononucleotide Transporter BACvac02_0232 ENOG4105E0C molybdate abc transporter BACvac02_0235 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BACvac02_0238 ENOG4105EGI Transcriptional regulator BACvac02_0243 ENOG4105F6E Acyl-transferase BACvac02_0246 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BACvac02_0249 ENOG4108RE7 deoxyribonuclease BACvac02_0250 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BACvac02_0255 ENOG4105C5H ABC transporter BACvac02_0258 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BACvac02_0260 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACvac02_0261 ENOG4105C3U ABC transporter BACvac02_0262 ENOG4108JQ7 (ABC) transporter BACvac02_0270 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BACvac02_0271 ENOG4105ERH Fumarylacetoacetate hydrolase BACvac02_0273 ENOG4108SC4 )-transporter BACvac02_0274 ENOG4105CPF Cell wall formation (By similarity) BACvac02_0276 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BACvac02_0279 ENOG4107ZXI Rhomboid family BACvac02_0281 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BACvac02_0282 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BACvac02_0284 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BACvac02_0306 ENOG4105K8N protein family UPF0079, ATPase BACvac02_0307 ENOG41072GX Peptidase M22 Glycoprotease BACvac02_0308 ENOG410801F ribosomal-protein-alanine acetyltransferase BACvac02_0309 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BACvac02_0310 ENOG4105C5H ABC transporter BACvac02_0313 ENOG4108TYN CAAX amino terminal protease family protein BACvac02_0317 ENOG4105C7N Xanthine uracil vitamin C permease BACvac02_0319 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_0320 ENOG4105BZU Histidine kinase BACvac02_0333 ENOG4108SHN Glycosyl transferase, family 2 BACvac02_0339 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BACvac02_0343 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_0349 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BACvac02_0350 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BACvac02_0351 ENOG4105C83 adenylosuccinate lyase BACvac02_0353 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BACvac02_0359 ENOG4108V3E phosphoribosylglycinamide formyltransferase BACvac02_0361 ENOG4105C12 Phosphoribosylglycinamide synthetase BACvac02_0367 ENOG4105C4R Atp-dependent dna helicase BACvac02_0375 ENOG4108W2Y isochorismatase BACvac02_0376 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_0377 ENOG4108UMI ABC transporter, permease BACvac02_0378 ENOG4105D01 (LipO)protein BACvac02_0382 ENOG410834F Transcriptional regulator BACvac02_0387 ENOG4105CBD Diacylglycerol kinase BACvac02_0389 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BACvac02_0390 ENOG4108JPW Aminotransferase BACvac02_0392 ENOG4105C26 Dehydrogenase BACvac02_0393 ENOG4105KPY Small multidrug resistance protein BACvac02_0397 ENOG4105D9N nucleoside BACvac02_0398 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BACvac02_0402 ENOG4108W15 Protein of unknown function (DUF1456) BACvac02_0405 ENOG4105DTQ mandelate racemase muconate lactonizing BACvac02_0407 ENOG4105DFD Na H antiporter BACvac02_0411 ENOG4105D3R alkyl hydroperoxide reductase BACvac02_0412 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BACvac02_0414 ENOG4107W7X Aldolase BACvac02_0415 ENOG4105EHG Permease protein BACvac02_0416 ENOG4105DQ5 transport system permease protein BACvac02_0417 ENOG4108V5C ABC transporter BACvac02_0428 ENOG4105BZU Histidine kinase BACvac02_0432 ENOG410756H nucleotidyltransferase BACvac02_0433 ENOG4105D2S major facilitator superfamily BACvac02_0437 ENOG4105E5Q amino acid AbC transporter BACvac02_0438 ENOG4105EAB amino acid AbC transporter BACvac02_0440 ENOG4105C8Q Methyl-accepting chemotaxis BACvac02_0441 ENOG4105C8Q Methyl-accepting chemotaxis BACvac02_0443 ENOG4105CI1 PTS System BACvac02_0450 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BACvac02_0453 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BACvac02_0456 ENOG4105C5H ABC transporter BACvac02_0462 ENOG41062JF Transcriptional regulator BACvac02_0466 ENOG4105DEU major facilitator superfamily BACvac02_0469 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BACvac02_0470 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BACvac02_0474 ENOG4108N0M stress protein BACvac02_0475 ENOG4106FN3 tellurium resistance protein BACvac02_0476 ENOG4106FN3 tellurium resistance protein BACvac02_0477 ENOG4107TS3 membrane protein, TerC BACvac02_0478 ENOG4108TTB tellurium resistance protein BACvac02_0482 ENOG4105KJF protein tyrosine phosphatase BACvac02_0484 ENOG4107U9T Pfam:Ribonuclease_BN BACvac02_0485 ENOG4105C59 p-type ATPase BACvac02_0486 ENOG4108IPJ Membrane BACvac02_0488 ENOG4105C3F Signal peptidase i BACvac02_0491 ENOG4107ZTW SNARE associated Golgi BACvac02_0494 ENOG410606W general stress protein BACvac02_0495 ENOG4105UPD Calcium Proton BACvac02_0503 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BACvac02_0504 ENOG4105VTR Integrase BACvac02_0562 ENOG4108JUB Transcriptional regulator BACvac02_0564 ENOG4108IQI permease BACvac02_0570 ENOG4105CSV Glutaminase BACvac02_0573 ENOG4108A04 Beta-lactamase BACvac02_0576 ENOG4105CKK Glycosyl transferase, family 2 BACvac02_0578 ENOG4107QQG Dehydrogenase BACvac02_0579 ENOG4105C3I Nad-dependent epimerase dehydratase BACvac02_0583 ENOG4105F1A Pyruvate formate-lyase BACvac02_0587 ENOG4105CI2 imidazolone-5-propionate hydrolase BACvac02_0588 ENOG4105ECP epimerase BACvac02_0593 ENOG41067AE Membrane-bound metal-dependent hydrolase BACvac02_0594 ENOG4105CEN a g-specific adenine glycosylase BACvac02_0595 ENOG4106BXE BACvac02_0599 ENOG4105BZ1 (ABC) transporter BACvac02_0600 ENOG4107NBY Membrane BACvac02_0601 ENOG4105CBC glutamate synthase BACvac02_0602 ENOG4105CBC glutamate synthase BACvac02_0604 ENOG4108IUW ABC transporter BACvac02_0608 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BACvac02_0609 ENOG4105G5W regulator Fur family BACvac02_0634 ENOG4108JQC penicillin-binding protein 1A BACvac02_0635 ENOG4107ZQN disulfide bond BACvac02_0637 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BACvac02_0639 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BACvac02_0640 ENOG4105BZU Histidine kinase BACvac02_0643 ENOG4105CYN Serine protein kinase BACvac02_0647 ENOG4105C94 Transporter BACvac02_0650 ENOG4105DZ6 Band 7 protein BACvac02_0652 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BACvac02_0654 ENOG4108V9W transcriptional regulatory protein BACvac02_0655 ENOG4105D4T Citrate transporter BACvac02_0659 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BACvac02_0660 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_0661 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BACvac02_0662 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BACvac02_0663 ENOG4105BZ7 extracellular solute-binding protein family 1 BACvac02_0664 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BACvac02_0665 ENOG4108STX response regulator BACvac02_0666 ENOG4105US7 Histidine kinase BACvac02_0671 ENOG4108MRH transcriptional regulatory protein BACvac02_0673 ENOG4105C6K Malic enzyme BACvac02_0677 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BACvac02_0679 ENOG4105BZU Histidine kinase BACvac02_0680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_0682 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BACvac02_0683 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BACvac02_0684 ENOG4108JB9 formate dehydrogenase BACvac02_0690 ENOG4105CUB amino acid BACvac02_0692 ENOG4105C59 p-type ATPase BACvac02_0693 ENOG4105DAP Nicotinate phosphoribosyltransferase BACvac02_0694 ENOG4105DAP Nicotinate phosphoribosyltransferase BACvac02_0703 ENOG41073R8 VanW family BACvac02_0704 ENOG4108KGH TRANSCRIPTIONal BACvac02_0705 ENOG4105D9N nucleoside BACvac02_0706 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BACvac02_0707 ENOG4105C37 (CBS) domain BACvac02_0708 ENOG4108IJ0 Aspartate ammonia-lyase BACvac02_0709 ENOG4105DAA L-lactate BACvac02_0712 ENOG4105DUX Transporter BACvac02_0713 ENOG4108MES Periplasmic binding protein BACvac02_0714 ENOG4105DQ5 transport system permease protein BACvac02_0715 ENOG4108IHU transport system permease protein BACvac02_0716 ENOG4105E0A ABC, transporter BACvac02_0717 ENOG4105DMQ Methyltransferase BACvac02_0719 ENOG4105EXW epimerase dehydratase BACvac02_0721 ENOG4107T89 von Willebrand factor, type A BACvac02_0722 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BACvac02_0723 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACvac02_0726 ENOG4105BZU Histidine kinase BACvac02_0727 ENOG4105D5Q Arginine ornithine antiporter BACvac02_0728 ENOG4107414 GntR family transcriptional regulator BACvac02_0729 ENOG4105C5Y PTS System BACvac02_0730 ENOG4105CG3 alpha amylase, catalytic region BACvac02_0733 ENOG4105E1K spore germination protein BACvac02_0735 ENOG4105CRN Aminoglycoside phosphotransferase BACvac02_0736 ENOG4105BZG amino acid carrier protein BACvac02_0737 ENOG4105BZG amino acid carrier protein BACvac02_0738 ENOG4105CDA abc transporter atp-binding protein BACvac02_0739 ENOG4105CT1 (ABC) transporter BACvac02_0740 ENOG4105EAD ABC transporter BACvac02_0741 ENOG4105DRP amino acid AbC transporter BACvac02_0742 ENOG4108IQI permease BACvac02_0747 ENOG4105D29 Helix-turn-helix type 11 domain protein BACvac02_0748 ENOG4105NAE bifunctional deaminase-reductase domain protein BACvac02_0749 ENOG4105BZU Histidine kinase BACvac02_0752 ENOG4105CHH sulfate transporter BACvac02_0753 ENOG41068KF Universal stress protein BACvac02_0755 ENOG4105DEF Extracellular solute-binding protein, family 5 BACvac02_0757 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BACvac02_0758 ENOG4108JQ7 (ABC) transporter BACvac02_0760 ENOG4105CXY transporter BACvac02_0761 ENOG41067TZ transcriptional regulator, MarR family BACvac02_0763 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_0765 ENOG4105ETE Transcriptional regulator (LacI family BACvac02_0766 ENOG4108RVA ribokinase BACvac02_0768 ENOG4105C2J ABC transporter BACvac02_0769 ENOG4105CNN ABC, transporter BACvac02_0770 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BACvac02_0771 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BACvac02_0783 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BACvac02_0784 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BACvac02_0786 ENOG41069ER domain protein BACvac02_0787 ENOG4105VZ8 Transcriptional regulator BACvac02_0789 ENOG4107D63 BACvac02_0791 ENOG4105DUX Transporter BACvac02_0795 ENOG4105C85 amino acid BACvac02_0796 ENOG4105C7N Xanthine uracil vitamin C permease BACvac02_0797 ENOG4105C7N Xanthine uracil vitamin C permease BACvac02_0805 ENOG4105BZ9 Cytochrome C oxidase, subunit I BACvac02_0806 ENOG4105E2S oxidase) subunit II BACvac02_0809 ENOG4106CAD Protein of unknown function (DUF3311) BACvac02_0810 ENOG4105E1V na solute symporter BACvac02_0813 ENOG4108NHD germination protein BACvac02_0814 ENOG4105CE1 Ferrous iron transport protein b BACvac02_0816 ENOG4105CE1 Ferrous iron transport protein b BACvac02_0817 ENOG4105CE1 Ferrous iron transport protein b BACvac02_0818 ENOG4105CVA phosphate BACvac02_0819 ENOG4105C8U phosphate abc transporter BACvac02_0820 ENOG4105E2Z phosphate ABC transporter (Permease BACvac02_0849 ENOG41080XQ Signal transduction protein with cbs domains BACvac02_0854 ENOG4105ETU transcriptional activator (TenA BACvac02_0855 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_0857 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BACvac02_0859 ENOG4108VEU Thiamine monophosphate synthase BACvac02_0860 ENOG41080HI glycine oxidase BACvac02_0863 ENOG4105D06 uba thif-type nad fad binding protein BACvac02_0864 ENOG4105DWF phosphomethylpyrimidine kinase BACvac02_0873 ENOG4108INS Transcriptional regulator BACvac02_0876 ENOG4105C7N Xanthine uracil vitamin C permease BACvac02_0884 ENOG4105C5Y PTS System BACvac02_0891 ENOG4108B31 Spore germination protein BACvac02_0897 ENOG4107Y03 Nitroreductase BACvac02_0898 ENOG4105ED1 spovr family BACvac02_0905 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BACvac02_0906 ENOG4105XTG Pfam:DUF156 BACvac02_0907 ENOG4105VFE sira family BACvac02_0908 ENOG4107TPS domain protein BACvac02_0909 ENOG4105VFE sira family BACvac02_0910 ENOG41085GJ domain protein BACvac02_0913 ENOG41087NI Sulfite exporter TauE/SafE BACvac02_0915 ENOG4108KGH TRANSCRIPTIONal BACvac02_0920 ENOG4105EMD TRANSCRIPTIONal BACvac02_0921 ENOG4105VCP PTS System BACvac02_0922 ENOG4105VZJ PTS System BACvac02_0926 ENOG41069ER domain protein BACvac02_0927 ENOG4107RBB ABC transporter, permease BACvac02_0928 ENOG4105C19 ABC transporter BACvac02_0935 ENOG4105WEF catalase BACvac02_0942 ENOG4107T5V SNARE associated Golgi BACvac02_0948 ENOG4105CUB amino acid BACvac02_0949 ENOG4107RWR Sodium hydrogen exchanger BACvac02_0951 ENOG4106KNT transcriptional regulator BACvac02_0960 ENOG4108YXU transcriptional regulator AsnC family BACvac02_0962 ENOG4105KPY Small multidrug resistance protein BACvac02_0963 ENOG4105KPY Small multidrug resistance protein BACvac02_0968 ENOG4105NF4 modulator of drug activity BACvac02_0969 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BACvac02_0970 ENOG4105E5W Transporter BACvac02_0973 ENOG4107RKG DJ-1/PfpI family BACvac02_0975 ENOG4105CH6 catalase BACvac02_0978 ENOG4105D5Q Arginine ornithine antiporter BACvac02_0979 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BACvac02_0981 ENOG4105C26 Dehydrogenase BACvac02_0982 ENOG4105BZ1 (ABC) transporter BACvac02_0983 ENOG4105BZ1 (ABC) transporter BACvac02_0984 ENOG4105BZ1 (ABC) transporter BACvac02_0986 ENOG4105DRP amino acid AbC transporter BACvac02_0987 ENOG4105CDA abc transporter atp-binding protein BACvac02_0988 ENOG410839P BACvac02_0995 ENOG4107FQX Alpha-acetolactate decarboxylase BACvac02_1000 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BACvac02_1003 ENOG4105D4P Coproporphyrinogen iii oxidase BACvac02_1006 ENOG4105CHH sulfate transporter BACvac02_1015 ENOG4106AKK s-layer domain-containing protein BACvac02_1016 ENOG4106AKK s-layer domain-containing protein BACvac02_1018 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BACvac02_1019 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BACvac02_1022 ENOG4105CGU Enoyl-CoA hydratase BACvac02_1025 ENOG4105DER m42 family BACvac02_1029 ENOG4105CTU Proline racemase BACvac02_1030 ENOG4105CTU Proline racemase BACvac02_1039 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACvac02_1042 ENOG4108JQ7 (ABC) transporter BACvac02_1049 ENOG4105CSH Transporter BACvac02_1051 ENOG4108MRH transcriptional regulatory protein BACvac02_1060 ENOG4105CDU Replicative dna helicase BACvac02_1067 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_1078 ENOG4107P5I polyketide synthase BACvac02_1079 ENOG4108IG5 Transcriptional regulator BACvac02_1083 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BACvac02_1087 ENOG4105CMT Dihydroxyacetone kinase BACvac02_1089 ENOG4105CMT Dihydroxyacetone kinase BACvac02_1090 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BACvac02_1091 ENOG410847I Transcriptional regulator, BadM Rrf2 family BACvac02_1097 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BACvac02_1109 ENOG4105WN5 stage II sporulation protein BACvac02_1111 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_1113 ENOG4108MJI response regulator BACvac02_1114 ENOG4105BZU Histidine kinase BACvac02_1115 ENOG4105BZU Histidine kinase BACvac02_1120 ENOG4105K8R UPF0145 protein BACvac02_1125 ENOG4107VRP DNA repair exonuclease BACvac02_1126 ENOG4106D4I domain protein BACvac02_1127 ENOG4105D7V transposase BACvac02_1130 ENOG4108IND Tetr family transcriptional regulator BACvac02_1131 ENOG4105EQ0 Major Facilitator superfamily BACvac02_1134 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BACvac02_1137 ENOG4108MUZ hydrolase BACvac02_1141 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BACvac02_1144 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BACvac02_1148 ENOG4105EMN RNA polymerase sigma factor BACvac02_1153 ENOG4105C57 major facilitator superfamily BACvac02_1156 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_1158 ENOG4105EEM helicase BACvac02_1159 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BACvac02_1164 ENOG4105K59 histidine triad (HIT) protein BACvac02_1171 ENOG410905X membrane-flanked domain protein BACvac02_1173 ENOG4105CKV Membrane BACvac02_1181 ENOG410905X membrane-flanked domain protein BACvac02_1182 ENOG4105CKV Membrane BACvac02_1183 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BACvac02_1184 ENOG4105BZ4 penicillin-binding protein BACvac02_1185 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BACvac02_1187 ENOG4105C1Q protoporphyrinogen oxidase BACvac02_1193 ENOG4105NA0 Transcriptional regulator BACvac02_1196 ENOG4105ECB domain protein BACvac02_1202 ENOG4108RQ5 Beta-lactamase domain-containing protein BACvac02_1203 ENOG4105DF9 Lipoate-protein, ligase BACvac02_1205 ENOG4105CEY Amp-dependent synthetase and ligase BACvac02_1208 ENOG4105CNA YD repeat protein BACvac02_1212 ENOG4105CNA YD repeat protein BACvac02_1220 ENOG4105ENX hydrolase BACvac02_1222 ENOG4107RN3 metallophosphoesterase BACvac02_1223 ENOG4107TVP HD domain protein BACvac02_1225 ENOG4108AEY RNA polymerase sigma factor BACvac02_1226 ENOG41086D8 Transcriptional regulator BACvac02_1229 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_1233 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BACvac02_1234 ENOG4105C8Q Methyl-accepting chemotaxis BACvac02_1239 ENOG4105ZU5 s-layer protein BACvac02_1240 ENOG4107QP3 malate synthase g BACvac02_1243 ENOG4105VEQ Cold shock protein BACvac02_1246 ENOG4105XVF Competence transcription factor BACvac02_1249 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BACvac02_1250 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BACvac02_1251 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BACvac02_1259 ENOG4105ERH Fumarylacetoacetate hydrolase BACvac02_1260 ENOG4105ERH Fumarylacetoacetate hydrolase BACvac02_1265 ENOG4105CAQ asparagine synthetase BACvac02_1266 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BACvac02_1267 ENOG4105CH6 catalase BACvac02_1268 ENOG4105CH6 catalase BACvac02_1274 ENOG4105QNR S1 RNA binding domain protein BACvac02_1276 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BACvac02_1278 ENOG4107AYK membrAne BACvac02_1279 ENOG4107AYK membrAne BACvac02_1280 ENOG41073B9 BACvac02_1282 ENOG4108KP7 hydrolase BACvac02_1284 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BACvac02_1289 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BACvac02_1290 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BACvac02_1293 ENOG4105C31 Tryptophanyl-tRNA synthetase BACvac02_1296 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BACvac02_1297 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACvac02_1299 ENOG4108JQ7 (ABC) transporter BACvac02_1300 ENOG4105UQX Mate efflux family protein BACvac02_1305 ENOG4108ZCF integral membrane protein BACvac02_1307 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACvac02_1309 ENOG4105DPN Oligoendopeptidase f BACvac02_1312 ENOG4108Z18 K06886 hemoglobin BACvac02_1313 ENOG4105MIX Adenylate cyclase BACvac02_1316 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BACvac02_1321 ENOG4105CNI cell division protein FtsW BACvac02_1322 ENOG4105CNI cell division protein FtsW BACvac02_1324 ENOG4105K64 Glycosyl transferase, family 2 BACvac02_1329 ENOG4107TVC Glycosyl transferase, family 2 BACvac02_1333 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BACvac02_1334 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BACvac02_1336 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BACvac02_1346 ENOG4108WVJ 2'-5' rna ligase BACvac02_1351 ENOG4105CK7 Sodium proline symporter BACvac02_1352 ENOG4105CRQ synthase (Component I) BACvac02_1353 ENOG4105DDQ anthranilate synthase BACvac02_1372 ENOG4105C7S Dehydrogenase BACvac02_1373 ENOG4105C7S Dehydrogenase BACvac02_1375 ENOG4105VZ8 Transcriptional regulator BACvac02_1384 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BACvac02_1387 ENOG4105DZ1 carboxypeptidase BACvac02_1388 ENOG4105VFR signal peptidase BACvac02_1395 ENOG4105C26 Dehydrogenase BACvac02_1396 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_1397 ENOG4105F38 ABC transporter, permease BACvac02_1398 ENOG4105D38 putrescine abc transporter BACvac02_1399 ENOG4107RUE extracellular solute-binding protein family 1 BACvac02_1401 ENOG4105EYF MMPL domain protein BACvac02_1405 ENOG4105K4I Scp-like extracellular BACvac02_1406 ENOG4105K4I Scp-like extracellular BACvac02_1407 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BACvac02_1408 ENOG4105CQB FAD linked oxidase domain protein BACvac02_1411 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_1412 ENOG4105BZU Histidine kinase BACvac02_1413 ENOG4105JXH GntR family transcriptional regulator BACvac02_1417 ENOG4106A3R peptidase BACvac02_1419 ENOG4108QTI )-transporter BACvac02_1420 ENOG4107TS3 membrane protein, TerC BACvac02_1421 ENOG4105CZN Potassium uptake protein BACvac02_1422 ENOG410681C small acid-soluble spore protein BACvac02_1423 ENOG4108Z7G MaoC domain protein dehydratase BACvac02_1427 ENOG4105CHR reductase BACvac02_1429 ENOG4105MWK D-amino acid dehydrogenase, small subunit BACvac02_1434 ENOG4105C4Y ABC transporter BACvac02_1436 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_1438 ENOG4107RCV ABC transporter, permease BACvac02_1439 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BACvac02_1442 ENOG4105E98 transcriptional regulator DeoR family BACvac02_1447 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BACvac02_1451 ENOG4105PXI polysaccharide deacetylase BACvac02_1453 ENOG4105BZU Histidine kinase BACvac02_1454 ENOG41090MY MarR family Transcriptional regulator BACvac02_1456 ENOG4106DF1 BACvac02_1458 ENOG4105BZU Histidine kinase BACvac02_1460 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BACvac02_1461 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BACvac02_1469 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BACvac02_1470 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BACvac02_1472 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BACvac02_1473 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BACvac02_1474 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BACvac02_1475 ENOG4105CZV ABC transporter BACvac02_1477 ENOG4105CJ1 ABC, transporter BACvac02_1486 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BACvac02_1487 ENOG4105EA8 2-Nitropropane dioxygenase BACvac02_1488 ENOG4105EA8 2-Nitropropane dioxygenase BACvac02_1489 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BACvac02_1491 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BACvac02_1495 ENOG4105NQC Flavodoxin BACvac02_1502 ENOG4107QMU Mate efflux family protein BACvac02_1503 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BACvac02_1509 ENOG4105CZN Potassium uptake protein BACvac02_1510 ENOG41063Y9 BACvac02_1511 ENOG4105KBJ sporulation protein ytfj BACvac02_1516 ENOG4105CM2 brancheD-chain amino acid aminotransferase BACvac02_1517 ENOG4105C7K acetolactate synthase BACvac02_1518 ENOG4108ZP8 Acetolactate synthase small subunit BACvac02_1519 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BACvac02_1521 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BACvac02_1526 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BACvac02_1533 ENOG4107RVV histidinol phosphate phosphatase, hisj family BACvac02_1536 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BACvac02_1537 ENOG4107QZ2 Sulfatase BACvac02_1538 ENOG4105E0M Sulfatase BACvac02_1540 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BACvac02_1544 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BACvac02_1545 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BACvac02_1547 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BACvac02_1548 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BACvac02_1549 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BACvac02_1550 ENOG4105C8J )-transporter BACvac02_1554 ENOG4105DFD Na H antiporter BACvac02_1558 ENOG4105ENE Histidine kinase BACvac02_1559 ENOG4105WH1 Two component transcriptional regulator luxr family BACvac02_1562 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BACvac02_1567 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BACvac02_1571 ENOG4105CJ3 phosphate transporter BACvac02_1572 ENOG4107GRR phosphate transport regulator BACvac02_1573 ENOG4105BZ4 penicillin-binding protein BACvac02_1574 ENOG4105BZ4 penicillin-binding protein BACvac02_1577 ENOG4105BZU Histidine kinase BACvac02_1578 ENOG4105I3N Conserved Protein BACvac02_1581 ENOG4105BZU Histidine kinase BACvac02_1589 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BACvac02_1590 ENOG4105DZ1 carboxypeptidase BACvac02_1591 ENOG4108JIC nucleoside recognition domain protein BACvac02_1595 ENOG4107TWT Cytochrome c biogenesis protein BACvac02_1596 ENOG4105CRE cytochrome C BACvac02_1597 ENOG4105CRE cytochrome C BACvac02_1598 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_1599 ENOG4105BZU Histidine kinase BACvac02_1600 ENOG4108WBT adenosyltransferase BACvac02_1603 ENOG4108SAX Membrane BACvac02_1604 ENOG4108SAX Membrane BACvac02_1606 ENOG4105T7X BACvac02_1607 ENOG4105C9U ATP-dependent DNA helicase RecQ BACvac02_1608 ENOG4105I7S Abortive infection protein BACvac02_1611 ENOG4107X2D transcriptional regulator, merr family BACvac02_1612 ENOG4108S6Z Negative regulator of genetic competence BACvac02_1617 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BACvac02_1618 ENOG4105HDK L-asparaginase BACvac02_1624 ENOG4105S2F BACvac02_1630 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BACvac02_1631 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BACvac02_1634 ENOG4105XXQ heptaprenyl diphosphate synthase component I BACvac02_1636 ENOG4105EAH synthase BACvac02_1640 ENOG4105CIH Imidazole acetol-phosphate transaminase BACvac02_1642 ENOG41068YB TPR repeat-containing protein BACvac02_1645 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BACvac02_1646 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BACvac02_1647 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BACvac02_1654 ENOG4108JYZ YitT family BACvac02_1655 ENOG4108JYZ YitT family BACvac02_1656 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BACvac02_1659 ENOG4105FJR Lmbe family BACvac02_1660 ENOG4105CPK Glycosyl transferase (Group 1 BACvac02_1667 ENOG4105DVT helicase BACvac02_1668 ENOG4105YAC BACvac02_1672 ENOG4105CSM endonuclease III BACvac02_1674 ENOG4105BZ4 penicillin-binding protein BACvac02_1686 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BACvac02_1688 ENOG4105DVT helicase BACvac02_1689 ENOG4105CTD carboxy-peptidase BACvac02_1690 ENOG4105CTD carboxy-peptidase BACvac02_1693 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BACvac02_1696 ENOG4105C2W permease BACvac02_1697 ENOG4105DHF Membrane BACvac02_1699 ENOG410890F Dynamin family BACvac02_1701 ENOG4108W0I acetyltransferase BACvac02_1703 ENOG4105KHC sulfurtransferase BACvac02_1706 ENOG4106032 Glutathionylspermidine synthase BACvac02_1715 ENOG4105D3Q Sugar transferase BACvac02_1720 ENOG4105CPK Glycosyl transferase (Group 1 BACvac02_1724 ENOG4108SZE gCN5-related N-acetyltransferase BACvac02_1728 ENOG41081VK Ribonuclease BACvac02_1742 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACvac02_1744 ENOG4107RWR Sodium hydrogen exchanger BACvac02_1745 ENOG4105CN5 Metallo-Beta-Lactamase BACvac02_1746 ENOG4108Z5V transcriptional regulator, merr family BACvac02_1748 ENOG4105H67 Protein of unknown function (DUF421) BACvac02_1750 ENOG41080C8 DUF218 domain BACvac02_1761 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BACvac02_1763 ENOG4107R0U MotA TolQ exbB proton channel BACvac02_1764 ENOG4105ER2 Ompa motb domain protein BACvac02_1765 ENOG4107YTP response regulator receiver protein BACvac02_1768 ENOG4105DD5 Flagellar motor switch protein BACvac02_1772 ENOG4105BZU Histidine kinase BACvac02_1776 ENOG4105E1Q flagellar hook-associated protein BACvac02_1782 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BACvac02_1783 ENOG4108ZC9 flagellar basal-body rod protein flgc BACvac02_1784 ENOG41075Z6 flagellar hook-basal body complex protein fliE BACvac02_1787 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BACvac02_1795 ENOG4105BZE flagellar hook protein, FlgE BACvac02_1802 ENOG4105K64 Glycosyl transferase, family 2 BACvac02_1809 ENOG4107TVC Glycosyl transferase, family 2 BACvac02_1815 ENOG4105I03 Flagellin BACvac02_1816 ENOG4105E4C Lytic transglycosylase catalytic BACvac02_1820 ENOG4105DD5 Flagellar motor switch protein BACvac02_1822 ENOG4105CN7 Flagellar biosynthetic protein FliP BACvac02_1823 ENOG4105VS8 Flagellar biosynthetic protein fliq BACvac02_1825 ENOG4105D00 flagellar biosynthetic protein flhB BACvac02_1826 ENOG4105D7B Flagellar biosynthesis protein flha BACvac02_1827 ENOG4105FZW flagellar biosynthesis regulator FlhF BACvac02_1828 ENOG4105KTQ flagellar basal-body rod protein BACvac02_1829 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BACvac02_1834 ENOG4108RZE Tetr family transcriptional regulator BACvac02_1837 ENOG4105KAC Antibiotic biosynthesis monooxygenase BACvac02_1842 ENOG4105DUM transcriptional regulator, lysR family BACvac02_1843 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_1844 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BACvac02_1845 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BACvac02_1846 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BACvac02_1853 ENOG4105CVJ phosphoglycerate mutase BACvac02_1859 ENOG4105CAQ asparagine synthetase BACvac02_1864 ENOG4105PGM cation diffusion facilitator family transporter BACvac02_1866 ENOG4105DRR Transcriptional regulator, GntR family BACvac02_1867 ENOG4108UZ3 Transporter BACvac02_1868 ENOG4108UZ3 Transporter BACvac02_1869 ENOG4105CKI cobalamin synthesis protein BACvac02_1870 ENOG4108PJD permease BACvac02_1873 ENOG4105DFD Na H antiporter BACvac02_1874 ENOG4105C9Q fumarate hydratase class II BACvac02_1877 ENOG4107QJQ Mate efflux family protein BACvac02_1878 ENOG4107QJQ Mate efflux family protein BACvac02_1880 ENOG4105EC3 peptidase S51, dipeptidase E BACvac02_1884 ENOG4107QIV Cytochrome c biogenesis protein BACvac02_1891 ENOG4106BRA Membrane BACvac02_1899 ENOG4105CJ1 ABC, transporter BACvac02_1904 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACvac02_1905 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BACvac02_1907 ENOG4108IJ0 Aspartate ammonia-lyase BACvac02_1908 ENOG4105C6K Malic enzyme BACvac02_1922 ENOG4105FVX BACvac02_1923 ENOG4105FVX BACvac02_1931 ENOG4105CSR polyphosphate kinase 2 BACvac02_1936 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BACvac02_1939 ENOG4105EU0 Major facilitator Superfamily BACvac02_1940 ENOG4105C6T cysteine synthase BACvac02_1945 ENOG4105C8J )-transporter BACvac02_1947 ENOG4105X5K response regulator receiver protein BACvac02_1948 ENOG4105H67 Protein of unknown function (DUF421) BACvac02_1954 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BACvac02_1955 ENOG4105CHR reductase BACvac02_1956 ENOG4105CM2 brancheD-chain amino acid aminotransferase BACvac02_1957 ENOG4105C7K acetolactate synthase BACvac02_1959 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BACvac02_1961 ENOG4105C7B Threonine dehydratase BACvac02_1965 ENOG4105C6X Major Facilitator BACvac02_1967 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BACvac02_1969 ENOG4105DY9 regulatoR BACvac02_1970 ENOG4105CYC Transferase BACvac02_1974 ENOG4105F6J Alpha beta hydrolase fold BACvac02_1976 ENOG4108J59 Extracellular solute-binding protein, family 5 BACvac02_1984 ENOG41068WN BACvac02_1989 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BACvac02_1990 ENOG4105C72 UPF0176 protein BACvac02_1992 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BACvac02_2000 ENOG4107RHR regulatoR BACvac02_2002 ENOG4105D9N nucleoside BACvac02_2003 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BACvac02_2012 ENOG4107RAQ aminopeptidase BACvac02_2013 ENOG4107STQ Multicopper oxidase BACvac02_2024 ENOG4108T5E Copper resistance protein BACvac02_2025 ENOG4105KTB nuclear export factor GLE1 BACvac02_2027 ENOG4107RT3 EamA-like transporter family BACvac02_2028 ENOG4105GZI Transcriptional regulator BACvac02_2029 ENOG4108Z40 Transcriptional regulator BACvac02_2030 ENOG4107ZXU DSBA oxidoreductase BACvac02_2031 ENOG4108TVJ Nitroreductase BACvac02_2034 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BACvac02_2035 ENOG4106F5Q Membrane BACvac02_2036 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BACvac02_2038 ENOG4105CKI cobalamin synthesis protein BACvac02_2042 ENOG4108Z7G MaoC domain protein dehydratase BACvac02_2043 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BACvac02_2045 ENOG4105C0Z ABC transporter BACvac02_2046 ENOG4108IV0 ABC, transporter BACvac02_2047 ENOG4105C32 Amino acid ABC transporter (Permease) BACvac02_2049 ENOG4105SKE transcriptional Regulator LysR family BACvac02_2056 ENOG4105C4M (Ubiquinol oxidase) subunit I BACvac02_2057 ENOG4105C4M (Ubiquinol oxidase) subunit I BACvac02_2058 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BACvac02_2059 ENOG4108JJ9 ABC, transporter BACvac02_2060 ENOG4108JJ9 ABC, transporter BACvac02_2061 ENOG4108JJ8 (ABC) transporter BACvac02_2069 ENOG4105BZ1 (ABC) transporter BACvac02_2070 ENOG4105BZ1 (ABC) transporter BACvac02_2071 ENOG4105BZ1 (ABC) transporter BACvac02_2072 ENOG4105EFI regulatoR BACvac02_2073 ENOG4105BZU Histidine kinase BACvac02_2077 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BACvac02_2078 ENOG4108ZJ4 polysaccharide deacetylase BACvac02_2085 ENOG4105D6E homoserine dehydrogenase BACvac02_2090 ENOG4108KGH TRANSCRIPTIONal BACvac02_2092 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_2093 ENOG4105BZU Histidine kinase BACvac02_2094 ENOG4107VMI polysaccharide deacetylase BACvac02_2096 ENOG4105KT7 mgtC SapB transporter BACvac02_2098 ENOG4105VRR gCN5-related N-acetyltransferase BACvac02_2100 ENOG4105DUU IucA IucC family protein BACvac02_2101 ENOG4105CEY Amp-dependent synthetase and ligase BACvac02_2104 ENOG4108WBH protein TIM barrel BACvac02_2105 ENOG4105YWU small acid-soluble spore protein BACvac02_2109 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BACvac02_2121 ENOG4105KRN Transcriptional regulator, abrb family BACvac02_2123 ENOG4105YVS arsR family transcriptional regulator BACvac02_2124 ENOG4107SET aldo keto reductase BACvac02_2125 ENOG4107XZQ multidrug resistance protein BACvac02_2130 ENOG4105C8Q Methyl-accepting chemotaxis BACvac02_2132 ENOG4108K88 Membrane BACvac02_2133 ENOG4108WPJ Ferritin-like domain BACvac02_2136 ENOG4105DEN Luciferase family BACvac02_2140 ENOG4107QM2 Aldo Keto reductase BACvac02_2141 ENOG4105CKI cobalamin synthesis protein BACvac02_2149 ENOG4105DSE periplasmic solute binding protein BACvac02_2152 ENOG4105K4T epimerase BACvac02_2154 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BACvac02_2159 ENOG4105CVJ phosphoglycerate mutase BACvac02_2164 ENOG4107T5V SNARE associated Golgi BACvac02_2167 ENOG4108PJD permease BACvac02_2169 ENOG4108S4H thioesterase Superfamily protein BACvac02_2170 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BACvac02_2175 ENOG4105SXS Protein of unknown function (DUF456) BACvac02_2176 ENOG4105C37 (CBS) domain BACvac02_2181 ENOG4108Z7R Chaperone CsaA BACvac02_2183 ENOG4108ZRV stage ii sporulation protein p BACvac02_2185 ENOG4108VXD carboxy-peptidase BACvac02_2188 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BACvac02_2193 ENOG4108X4Q Hydrolase BACvac02_2195 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BACvac02_2196 ENOG4107RBS Methyltransferase BACvac02_2199 ENOG41087PP glycosyltransferase MGT family BACvac02_2200 ENOG4108JYZ YitT family BACvac02_2201 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BACvac02_2208 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BACvac02_2216 ENOG4105KBJ sporulation protein ytfj BACvac02_2221 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BACvac02_2226 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BACvac02_2227 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_2229 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BACvac02_2230 ENOG4105EMN RNA polymerase sigma factor BACvac02_2235 ENOG4108V06 Glutathione peroxidase BACvac02_2238 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BACvac02_2242 ENOG4108IUE nitrate reductase beta subunit BACvac02_2243 ENOG4105R3A Nitrate reductase BACvac02_2248 ENOG4107V6Q Cyclic nucleotide-binding domain BACvac02_2249 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BACvac02_2250 ENOG4105D06 uba thif-type nad fad binding protein BACvac02_2251 ENOG4105CVM Molybdenum cofactor synthesis domain protein BACvac02_2252 ENOG4108ZAF Molybdopterin BACvac02_2258 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BACvac02_2259 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BACvac02_2260 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BACvac02_2261 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BACvac02_2262 ENOG4108IFG nitrite reductase, (NAD(P)H) BACvac02_2263 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BACvac02_2270 ENOG4105MCT stage V sporulation protein S BACvac02_2274 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BACvac02_2279 ENOG4105C5H ABC transporter BACvac02_2282 ENOG4108UUM single-stranded DNA-binding protein BACvac02_2290 ENOG4107YX5 Pfam:DUF548 BACvac02_2291 ENOG4105C75 arginyL-tRNA synthetase BACvac02_2297 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BACvac02_2300 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BACvac02_2301 ENOG4105C5S asparaginyl-tRNA synthetase BACvac02_2305 ENOG4105EC2 ftsk spoIIIe BACvac02_2323 ENOG4105BZW Glycerate kinase BACvac02_2324 ENOG4107QPK )-transporter BACvac02_2325 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_2326 ENOG41062D9 Histidine kinase BACvac02_2330 ENOG4105C8J )-transporter BACvac02_2334 ENOG4107XGZ Hydrolase BACvac02_2335 ENOG4105CY2 Citrate transporter BACvac02_2336 ENOG4105C0A alcohol dehydrogenase BACvac02_2340 ENOG4105KD7 acetyltransferase BACvac02_2349 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BACvac02_2354 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BACvac02_2357 ENOG4107RVG penicillin-binding protein BACvac02_2358 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BACvac02_2359 ENOG4105E9Q Acyl-transferase BACvac02_2360 ENOG4108UT2 hemolysin iii BACvac02_2362 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BACvac02_2364 ENOG4108RCR degv family BACvac02_2366 ENOG4105E8R UPF0173 metal-dependent hydrolase BACvac02_2367 ENOG4108KF3 Electron transport protein SCO1 SenC BACvac02_2368 ENOG4107Y70 Heat shock protein BACvac02_2369 ENOG4105CAQ asparagine synthetase BACvac02_2373 ENOG4108MES Periplasmic binding protein BACvac02_2374 ENOG4105F0I Aminotransferase BACvac02_2382 ENOG4105D8X mechanosensitive ion channel BACvac02_2383 ENOG4105BZU Histidine kinase BACvac02_2384 ENOG4105WH1 Two component transcriptional regulator luxr family BACvac02_2394 ENOG4105CMG Carbohydrate kinase BACvac02_2401 ENOG4108IJ8 ABC transporter BACvac02_2402 ENOG4105E90 ABC transporter BACvac02_2411 ENOG4105C37 (CBS) domain BACvac02_2417 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACvac02_2420 ENOG4107S4Y M20 DapE family protein YgeY BACvac02_2421 ENOG4108TSC N-acetyltransferase BACvac02_2422 ENOG4108JUB Transcriptional regulator BACvac02_2423 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BACvac02_2424 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BACvac02_2431 ENOG4108N23 SpoOM-related protein BACvac02_2432 ENOG410841Q phosphoesterase PA-phosphatase related protein BACvac02_2434 ENOG4105SZ6 Thioredoxin BACvac02_2437 ENOG4108IBT Inherit from COG: transposase BACvac02_2455 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BACvac02_2463 ENOG4105BZ4 penicillin-binding protein BACvac02_2464 ENOG4105CZM Major Facilitator BACvac02_2465 ENOG4105W8X HesB YadR YfhF-family protein BACvac02_2467 ENOG4105DXD 2-methylcitrate dehydratase BACvac02_2468 ENOG4105CR4 methylisocitrate lyase BACvac02_2470 ENOG4105C1G acyl-Coa dehydrogenase BACvac02_2471 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BACvac02_2473 ENOG4105N14 lysine exporter protein LysE YggA BACvac02_2474 ENOG4105E39 Enoyl-CoA hydratase BACvac02_2477 ENOG4107RFY SbcCD D subunit BACvac02_2478 ENOG4105EYH Exonuclease BACvac02_2485 ENOG4105FCD Major Facilitator BACvac02_2486 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BACvac02_2487 ENOG4105E4F Isochorismate synthase BACvac02_2488 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BACvac02_2489 ENOG4105WQI isochorismatase BACvac02_2490 ENOG4105CEY Amp-dependent synthetase and ligase BACvac02_2491 ENOG4105WQT MbtH domain protein BACvac02_2492 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_2495 ENOG4105K70 DNA-binding protein BACvac02_2500 ENOG4105BZG amino acid carrier protein BACvac02_2506 ENOG4105C22 threonyL-tRNA synthetase BACvac02_2507 ENOG4105C19 ABC transporter BACvac02_2510 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BACvac02_2516 ENOG4108D32 Methyltransferase BACvac02_2523 ENOG41081I9 integral membrane protein BACvac02_2525 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BACvac02_2527 ENOG4105EYF MMPL domain protein BACvac02_2532 ENOG4105WCN acetyltransferase BACvac02_2538 ENOG4105C1Q protoporphyrinogen oxidase BACvac02_2540 ENOG41068WN BACvac02_2542 ENOG4105VEQ Cold shock protein BACvac02_2547 ENOG410667J hydrolase BACvac02_2555 ENOG4107V2S Transcriptional regulator BACvac02_2556 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BACvac02_2559 ENOG4105DND Transcriptional regulator BACvac02_2560 ENOG4108RPX mosc domain containing protein BACvac02_2564 ENOG4105BZ1 (ABC) transporter BACvac02_2565 ENOG4105BZ1 (ABC) transporter BACvac02_2566 ENOG4105BZ1 (ABC) transporter BACvac02_2569 ENOG4108JCI Transcriptional regulator BACvac02_2575 ENOG4108KPJ rna polymerase sigma factor BACvac02_2581 ENOG4105F32 YngK protein BACvac02_2586 ENOG4105RD7 BadF BadG BcrA BcrD BACvac02_2588 ENOG4107STF Involved in phosphonate degradation (By similarity) BACvac02_2592 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BACvac02_2595 ENOG4105C1J atp-dependent rna helicase BACvac02_2598 ENOG4108RZE Tetr family transcriptional regulator BACvac02_2602 ENOG41088CC tellurite resistance protein tehB BACvac02_2604 ENOG4108I0C methyltransferase BACvac02_2605 ENOG4107RA9 decarboxylase BACvac02_2606 ENOG41090HR transcriptional regulator BACvac02_2615 ENOG4105CIN aminoacyl-histidine dipeptidase BACvac02_2621 ENOG4107RF6 penicillin-binding protein BACvac02_2622 ENOG4107RF6 penicillin-binding protein BACvac02_2623 ENOG4107RF6 penicillin-binding protein BACvac02_2625 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BACvac02_2626 ENOG4105ETE Transcriptional regulator (LacI family BACvac02_2627 ENOG4105ETE Transcriptional regulator (LacI family BACvac02_2628 ENOG4105IE8 Alpha-ketoglutarate permease BACvac02_2629 ENOG4105CK5 oxidoreductase BACvac02_2635 ENOG4105D2N Aldolase BACvac02_2636 ENOG4105DH8 myo-inositol catabolism BACvac02_2639 ENOG4105CGH 5'-nucleotidase BACvac02_2643 ENOG4105VZ8 Transcriptional regulator BACvac02_2645 ENOG4108VXD carboxy-peptidase BACvac02_2650 ENOG41067SE Tetr family transcriptional regulator BACvac02_2651 ENOG4105C5H ABC transporter BACvac02_2653 ENOG4105BZU Histidine kinase BACvac02_2656 ENOG4106ANW SMI1_KNR4 BACvac02_2657 ENOG4105CEP NADH dehydrogenase BACvac02_2658 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BACvac02_2661 ENOG4105CJ1 ABC, transporter BACvac02_2663 ENOG4107Z3H Transcriptional regulator, TetR family BACvac02_2666 ENOG4105C1G acyl-Coa dehydrogenase BACvac02_2667 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BACvac02_2668 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BACvac02_2669 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BACvac02_2670 ENOG4105E39 Enoyl-CoA hydratase BACvac02_2671 ENOG4107QX3 carboxylase BACvac02_2672 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BACvac02_2674 ENOG4105WCN acetyltransferase BACvac02_2675 ENOG4105DBI uridine monophosphokinase BACvac02_2678 ENOG4105DZ1 carboxypeptidase BACvac02_2682 ENOG4105T9C HD domain BACvac02_2684 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BACvac02_2694 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BACvac02_2694 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BACvac02_2697 ENOG4105FQP Beta-lactamase BACvac02_2699 ENOG4107Y80 Major Facilitator superfamily BACvac02_2703 ENOG4105CUV Homoserine Kinase BACvac02_2710 ENOG4105CPQ Dehydrogenase BACvac02_2713 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BACvac02_2714 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BACvac02_2736 ENOG4105ETU transcriptional activator (TenA BACvac02_2757 ENOG410667J hydrolase BACvac02_2759 ENOG4105BZU Histidine kinase BACvac02_2761 ENOG4107RF6 penicillin-binding protein BACvac02_2765 ENOG4108JJB ABC transporter BACvac02_2768 ENOG4108HGU Histidine kinase BACvac02_2771 ENOG4105CB2 alcohol dehydrogenase BACvac02_2772 ENOG4105CJN penicillin-binding protein BACvac02_2773 ENOG4105CJN penicillin-binding protein BACvac02_2775 ENOG4105FQP Beta-lactamase BACvac02_2782 ENOG4108V4B ThiJ pfpI BACvac02_2788 ENOG4107Y80 Major Facilitator superfamily BACvac02_2792 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BACvac02_2797 ENOG4107Y9U Membrane BACvac02_2805 ENOG4105FCD Major Facilitator BACvac02_2808 ENOG4105E09 nadh pyrophosphatase BACvac02_2809 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BACvac02_2810 ENOG4108Z4K mutator MutT protein BACvac02_2817 ENOG4108XI2 Domain of unknown function (DUF1963) BACvac02_2823 ENOG4105KWG Pfam:DUF1696 BACvac02_2830 ENOG4105PKS Excinuclease abc c subunit domain protein BACvac02_2838 ENOG4107VFR oxidoreductase BACvac02_2843 ENOG4105PAD Hydrolase BACvac02_2848 ENOG4105DY8 decarboxylase BACvac02_2849 ENOG4105DY8 decarboxylase BACvac02_2852 ENOG4108IUM Glycogen debranching enzyme BACvac02_2857 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BACvac02_2858 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BACvac02_2860 ENOG4105FDR Membrane BACvac02_2867 ENOG4108V3A UPF0421 protein BACvac02_2871 ENOG4105MSI germination protein ypeb BACvac02_2875 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BACvac02_2876 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BACvac02_2877 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BACvac02_2878 ENOG4107Z3H Transcriptional regulator, TetR family BACvac02_2884 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BACvac02_2888 ENOG4105E98 transcriptional regulator DeoR family BACvac02_2892 ENOG41062ES Transcriptional regulator BACvac02_2897 ENOG4107QKR Dehydrogenase BACvac02_2899 ENOG4107RUY (E1 component), alpha subunit BACvac02_2901 ENOG4105E1F short-chain dehydrogenase reductase BACvac02_2902 ENOG4105RHY Pfam:UPF0157 BACvac02_2907 ENOG4107SQ8 Glycine betaine BACvac02_2909 ENOG4108IJ7 Glycine betaine BACvac02_2914 ENOG4105E66 phosphoriboisomerase A BACvac02_2915 ENOG41082BV acetyltransferase BACvac02_2916 ENOG4108M1A Chitin-binding protein BACvac02_2926 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BACvac02_2936 ENOG4105EEM helicase BACvac02_2940 ENOG4105C9U ATP-dependent DNA helicase RecQ BACvac02_2949 ENOG4108M1A Chitin-binding protein BACvac02_2952 ENOG4105BZG amino acid carrier protein BACvac02_2953 ENOG4105C26 Dehydrogenase BACvac02_2954 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BACvac02_2955 ENOG4105CTU Proline racemase BACvac02_2956 ENOG4105CTU Proline racemase BACvac02_2957 ENOG41080HI glycine oxidase BACvac02_2965 ENOG4107T5V SNARE associated Golgi BACvac02_2967 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BACvac02_2968 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BACvac02_2971 ENOG4105DTQ mandelate racemase muconate lactonizing BACvac02_2983 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BACvac02_2984 ENOG4105BZU Histidine kinase BACvac02_2985 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_2992 ENOG4105DPN Oligoendopeptidase f BACvac02_2995 ENOG4105EPR degv family BACvac02_3003 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BACvac02_3004 ENOG4106K7D Major facilitator family transporter BACvac02_3008 ENOG4107BMA Transglycosylase associated protein BACvac02_3012 ENOG41089UC methyltransferase, type 11 BACvac02_3019 ENOG4105CHM Aminotransferase BACvac02_3025 ENOG4105DVE abc transporter atp-binding protein BACvac02_3034 ENOG4105C02 permease BACvac02_3037 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BACvac02_3038 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BACvac02_3039 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BACvac02_3044 ENOG4105E09 nadh pyrophosphatase BACvac02_3048 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BACvac02_3058 ENOG4107VC0 DNA alkylation repair enzyme BACvac02_3061 ENOG4107VMI polysaccharide deacetylase BACvac02_3063 ENOG4108ZCF integral membrane protein BACvac02_3064 ENOG4105E0M Sulfatase BACvac02_3065 ENOG4105C5H ABC transporter BACvac02_3069 ENOG4105EYF MMPL domain protein BACvac02_3070 ENOG41082JN Transcriptional regulator BACvac02_3074 ENOG4105CIH Imidazole acetol-phosphate transaminase BACvac02_3075 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BACvac02_3076 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BACvac02_3085 ENOG41069ER domain protein BACvac02_3089 ENOG4105EMN RNA polymerase sigma factor BACvac02_3093 ENOG4105D4B ABC, transporter BACvac02_3096 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BACvac02_3098 ENOG4105DKT Transcriptional regulator BACvac02_3099 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BACvac02_3102 ENOG41061GT Aldolase BACvac02_3106 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BACvac02_3112 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BACvac02_3114 ENOG4105II7 pyrroline-5-carboxylate reductase BACvac02_3117 ENOG4107258 Transcriptional regulator BACvac02_3119 ENOG4105E0Y RtcB Protein BACvac02_3121 ENOG4105ECK Fatty Acid Desaturase BACvac02_3122 ENOG4105G6Z alkaline phosphatase BACvac02_3124 ENOG4105VMP Transcriptional regulator BACvac02_3128 ENOG41090T1 Membrane BACvac02_3130 ENOG4108WCX response regulator BACvac02_3132 ENOG41068WN BACvac02_3137 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BACvac02_3141 ENOG4105CKK Glycosyl transferase, family 2 BACvac02_3145 ENOG4105CKK Glycosyl transferase, family 2 BACvac02_3147 ENOG4105C8Y Acetylornithine aminotransferase BACvac02_3156 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BACvac02_3158 ENOG4108TVJ Nitroreductase BACvac02_3159 ENOG4105FS7 Transcriptional regulator BACvac02_3168 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BACvac02_3171 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BACvac02_3178 ENOG4108XET gCN5-related N-acetyltransferase BACvac02_3194 ENOG410635A Membrane BACvac02_3195 ENOG4105KNA -acetyltransferase BACvac02_3196 ENOG4108IQI permease BACvac02_3198 ENOG4105F1N DNA alkylation repair BACvac02_3207 ENOG4107RF6 penicillin-binding protein BACvac02_3209 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BACvac02_3216 ENOG4105P4J Allophanate hydrolase, subunit 1 BACvac02_3217 ENOG4107258 Transcriptional regulator BACvac02_3219 ENOG4106N3A copper homeostasis protein cutc BACvac02_3220 ENOG4108ZRV stage ii sporulation protein p BACvac02_3221 ENOG4108ZHR arsR family transcriptional regulator BACvac02_3223 ENOG4105FDT acyl-CoA dehydrogenase BACvac02_3227 ENOG4105DWD nucleoside recognition domain protein BACvac02_3228 ENOG4105DWD nucleoside recognition domain protein BACvac02_3234 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BACvac02_3249 ENOG4105E2A Dehydrogenase BACvac02_3253 ENOG4108IJ0 Aspartate ammonia-lyase BACvac02_3255 ENOG4105HDK L-asparaginase BACvac02_3256 ENOG4108IMY Transcriptional regulator BACvac02_3258 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BACvac02_3259 ENOG4105CUB amino acid BACvac02_3261 ENOG4105II7 pyrroline-5-carboxylate reductase BACvac02_3264 ENOG4105C6K Malic enzyme BACvac02_3267 ENOG4108NHD germination protein BACvac02_3274 ENOG4105CSV Glutaminase BACvac02_3281 ENOG4105CGH 5'-nucleotidase BACvac02_3282 ENOG4105CH6 catalase BACvac02_3284 ENOG4105CHJ isochorismatase hydrolase BACvac02_3297 ENOG4108606 TspO/MBR family BACvac02_3298 ENOG4105CVP deoxyribo-dipyrimidine photolyase BACvac02_3302 ENOG4108TWJ NADH dehydrogenase subunit 5 BACvac02_3303 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BACvac02_3305 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BACvac02_3306 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BACvac02_3307 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BACvac02_3309 ENOG4105DSE periplasmic solute binding protein BACvac02_3310 ENOG4105CC5 ABC transporter BACvac02_3311 ENOG4105DIK (ABC) transporter BACvac02_3317 ENOG4105D6J arsenicaL-resistance protein BACvac02_3318 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_3319 ENOG41085FC arsR family transcriptional regulator BACvac02_3322 ENOG4105F7F Chaperone BACvac02_3325 ENOG4105CHR reductase BACvac02_3326 ENOG4108YXU transcriptional regulator AsnC family BACvac02_3343 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BACvac02_3344 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_3346 ENOG4105IIP Membrane BACvac02_3349 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_3350 ENOG41062D9 Histidine kinase BACvac02_3356 ENOG4105K6H D-cysteine desulfhydrase BACvac02_3363 ENOG4105VZ8 Transcriptional regulator BACvac02_3366 ENOG4108NNI Beta-lactamase domain-containing protein BACvac02_3367 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BACvac02_3369 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BACvac02_3370 ENOG4105JQZ Methyltransferase BACvac02_3373 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BACvac02_3374 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BACvac02_3377 ENOG4105BZU Histidine kinase BACvac02_3380 ENOG4108U05 Transcriptional regulator BACvac02_3384 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BACvac02_3385 ENOG4105DJB Major Facilitator Superfamily BACvac02_3386 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BACvac02_3387 ENOG4107QR9 Iron-sulfur cluster binding protein BACvac02_3389 ENOG4106P55 Transcriptional regulator BACvac02_3391 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BACvac02_3398 ENOG4105TRI Hydrolase BACvac02_3407 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BACvac02_3414 ENOG4107QJQ Mate efflux family protein BACvac02_3419 ENOG4105EQ0 Major Facilitator superfamily BACvac02_3420 ENOG4108JGH Tetr family transcriptional regulator BACvac02_3422 ENOG4105C44 Serine transporter BACvac02_3423 ENOG4105EJQ L-serine dehydratase BACvac02_3427 ENOG4108JPW Aminotransferase BACvac02_3430 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BACvac02_3432 ENOG4105DVH amino acid BACvac02_3435 ENOG4108JQ1 Dehydrogenase BACvac02_3439 ENOG4108AEY RNA polymerase sigma factor BACvac02_3442 ENOG41082W1 Cupin 2, conserved barrel domain protein BACvac02_3443 ENOG410874W AraC family transcriptional regulator BACvac02_3448 ENOG4105HIR S-layer domain protein BACvac02_3458 ENOG4108ISG Major Facilitator BACvac02_3461 ENOG4105CZM Major Facilitator BACvac02_3465 ENOG4105DA5 (ABC) transporter BACvac02_3466 ENOG41069JR BACvac02_3469 ENOG4105KPY Small multidrug resistance protein BACvac02_3470 ENOG4105KBX Transcriptional regulator, TetR family BACvac02_3472 ENOG4105CRW Short chain fatty acid transporter BACvac02_3474 ENOG4105DYS nad(p)h dehydrogenase (quinone) BACvac02_3480 ENOG4108JJB ABC transporter BACvac02_3481 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BACvac02_3486 ENOG4108K8S endonuclease I BACvac02_3489 ENOG41067QW Transcriptional regulator BACvac02_3491 ENOG4108Z66 YbaK ebsC protein BACvac02_3493 ENOG4105CUT histidyl-tRNA synthetase BACvac02_3496 ENOG4105KVH Transcriptional regulator BACvac02_3497 ENOG4108RCM Nitroreductase BACvac02_3501 ENOG4108PSK reductase BACvac02_3503 ENOG4105CJ1 ABC, transporter BACvac02_3514 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_3517 ENOG4106UW1 Major Facilitator superfamily BACvac02_3518 ENOG4108UW5 maltose o-acetyltransferase BACvac02_3520 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BACvac02_3522 ENOG4105C31 Tryptophanyl-tRNA synthetase BACvac02_3523 ENOG4105C31 Tryptophanyl-tRNA synthetase BACvac02_3524 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BACvac02_3528 ENOG4105DMQ Methyltransferase BACvac02_3530 ENOG4105EV4 Multidrug resistance protein mdtH BACvac02_3536 ENOG4105C37 (CBS) domain BACvac02_3539 ENOG4105DDN Pentapeptide repeat-containing protein BACvac02_3540 ENOG4105XDF Protein of unknown function (DUF1272) BACvac02_3541 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BACvac02_3542 ENOG4105CMG Carbohydrate kinase BACvac02_3543 ENOG4105C6Z Gluconate BACvac02_3544 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BACvac02_3547 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BACvac02_3548 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BACvac02_3549 ENOG4105CIS alcohol dehydrogenase BACvac02_3550 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BACvac02_3553 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BACvac02_3554 ENOG4105D4Y metalloprotease BACvac02_3559 ENOG4105CV8 reductase BACvac02_3560 ENOG4105F27 Major Facilitator BACvac02_3563 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BACvac02_3564 ENOG4105C44 Serine transporter BACvac02_3570 ENOG4105KVH Transcriptional regulator BACvac02_3571 ENOG4108TZY GntR Family Transcriptional Regulator BACvac02_3572 ENOG4105D9R oxidoreductase BACvac02_3574 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BACvac02_3575 ENOG4105KVH Transcriptional regulator BACvac02_3576 ENOG4105KVH Transcriptional regulator BACvac02_3583 ENOG4105JAB phenazine biosynthesis protein, phzf family BACvac02_3585 ENOG4105CHR reductase BACvac02_3590 ENOG4105KVH Transcriptional regulator BACvac02_3595 ENOG4108ZJ4 polysaccharide deacetylase BACvac02_3612 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BACvac02_3615 ENOG4107YXZ hydrolase, family 25 BACvac02_3619 ENOG4105ED2 Beta-lactamase BACvac02_3621 ENOG4105H3G oxidoreductase BACvac02_3628 ENOG4105CIS alcohol dehydrogenase BACvac02_3635 ENOG4108TN2 lmbE family BACvac02_3637 ENOG4107R3E Citrate transporter BACvac02_3640 ENOG4108MES Periplasmic binding protein BACvac02_3642 ENOG4105EHG Permease protein BACvac02_3643 ENOG4105DQ5 transport system permease protein BACvac02_3644 ENOG4105NX3 Membrane BACvac02_3645 ENOG4107ZY0 Phenazine biosynthesis-like protein BACvac02_3649 ENOG4107CUJ Protein of unknown function (DUF2690) BACvac02_3651 ENOG4107V2S Transcriptional regulator BACvac02_3656 ENOG4105C98 muts2 protein BACvac02_3658 ENOG4105E5K Alpha-amylase BACvac02_3659 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BACvac02_3661 ENOG4105DPN Oligoendopeptidase f BACvac02_3663 ENOG4108A04 Beta-lactamase BACvac02_3669 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BACvac02_3673 ENOG41082BM Transcriptional regulator, arsr family BACvac02_3674 ENOG4105CIS alcohol dehydrogenase BACvac02_3680 ENOG4105RHY Pfam:UPF0157 BACvac02_3682 ENOG4105C09 Bile acid BACvac02_3683 ENOG4105CQB FAD linked oxidase domain protein BACvac02_3688 ENOG4108UT6 Transferase hexapeptide repeat containing protein BACvac02_3690 ENOG4105K64 Glycosyl transferase, family 2 BACvac02_3691 ENOG4105E39 Enoyl-CoA hydratase BACvac02_3693 ENOG4105KT7 mgtC SapB transporter BACvac02_3695 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_3696 ENOG41073R8 VanW family BACvac02_3699 ENOG4108R1P BACvac02_3704 ENOG4105VEQ Cold shock protein BACvac02_3709 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BACvac02_3713 ENOG410904N short-chain dehydrogenase reductase BACvac02_3715 ENOG4106IQC argininosuccinate lyase BACvac02_3718 ENOG4108IA2 Sodium pantothenate symporter BACvac02_3720 ENOG4105C26 Dehydrogenase BACvac02_3721 ENOG4105CHR reductase BACvac02_3723 ENOG4105EWU Squalene--hopene cyclase BACvac02_3725 ENOG4105FR1 rard protein BACvac02_3726 ENOG410696E Membrane BACvac02_3729 ENOG4105D1F ATP-binding protein BACvac02_3731 ENOG4108ZAF Molybdopterin BACvac02_3732 ENOG4105CVM Molybdenum cofactor synthesis domain protein BACvac02_3733 ENOG4105D06 uba thif-type nad fad binding protein BACvac02_3734 ENOG4105TMB Formate nitrite transporter BACvac02_3737 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BACvac02_3738 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BACvac02_3740 ENOG4108JB9 formate dehydrogenase BACvac02_3741 ENOG4105E1K spore germination protein BACvac02_3754 ENOG4107QJT sodium dicarboxylate symporter BACvac02_3756 ENOG4108KGH TRANSCRIPTIONal BACvac02_3758 ENOG4105EMN RNA polymerase sigma factor BACvac02_3763 ENOG4105CIG ABC transporter BACvac02_3765 ENOG4105D9R oxidoreductase BACvac02_3767 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BACvac02_3768 ENOG4105K4P CoA-binding domain protein BACvac02_3769 ENOG4105C0H protease BACvac02_3770 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_3773 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BACvac02_3774 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BACvac02_3775 ENOG4105W8X HesB YadR YfhF-family protein BACvac02_3781 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BACvac02_3782 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BACvac02_3783 ENOG4108JJA ABC, transporter BACvac02_3784 ENOG4108I0Z Aconitate hydratase BACvac02_3785 ENOG4108I0Z Aconitate hydratase BACvac02_3791 ENOG4105E5W Transporter BACvac02_3793 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BACvac02_3797 ENOG4107F3J Amp-dependent synthetase and ligase BACvac02_3798 ENOG4107ZYJ bioY protein BACvac02_3799 ENOG4105CEY Amp-dependent synthetase and ligase BACvac02_3810 ENOG4107AYK membrAne BACvac02_3812 ENOG4105BZU Histidine kinase BACvac02_3813 ENOG4105FBA Phospholipase Carboxylesterase BACvac02_3814 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BACvac02_3815 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BACvac02_3816 ENOG4105CK7 Sodium proline symporter BACvac02_3818 ENOG4105CBC glutamate synthase BACvac02_3819 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BACvac02_3820 ENOG4108VJ1 Transcriptional regulator (CarD family BACvac02_3821 ENOG4108903 Formimidoylglutamase BACvac02_3827 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BACvac02_3838 ENOG4107QIV Cytochrome c biogenesis protein BACvac02_3840 ENOG4107RSM transcriptional regulator BACvac02_3841 ENOG4105VAW lrga family BACvac02_3842 ENOG41067MG lrgb family BACvac02_3849 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BACvac02_3852 ENOG4105BZ1 (ABC) transporter BACvac02_3853 ENOG4105BZ1 (ABC) transporter BACvac02_3857 ENOG4105D7V transposase BACvac02_3860 ENOG4105D5T phosphonate abc transporter BACvac02_3865 ENOG4108SVB resolvase BACvac02_3869 ENOG4105K7K Transcriptional regulator BACvac02_3878 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BACvac02_3879 ENOG4105XSJ toxin secretion phage lysis holin BACvac02_3921 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BACvac02_3942 ENOG4105C5F glutamine synthetase BACvac02_3943 ENOG4105KV4 Transcriptional regulator BACvac02_3944 ENOG4105CXI aluminum resistance protein BACvac02_3945 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BACvac02_3946 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BACvac02_3947 ENOG4105EN6 Membrane BACvac02_3948 ENOG4106F1P AAA ATPase, central domain protein BACvac02_3954 ENOG41069ER domain protein BACvac02_3955 ENOG4105DM4 PTS System BACvac02_3956 ENOG4105DE4 1-phosphofructokinase BACvac02_3957 ENOG4105E98 transcriptional regulator DeoR family BACvac02_3961 ENOG4108SJC Membrane BACvac02_3964 ENOG4105C85 amino acid BACvac02_3968 ENOG4105TMB Formate nitrite transporter BACvac02_3969 ENOG4105TMB Formate nitrite transporter BACvac02_3970 ENOG4105K70 DNA-binding protein BACvac02_3971 ENOG4105C59 p-type ATPase BACvac02_3972 ENOG4105C59 p-type ATPase BACvac02_3973 ENOG410681U heavy metal transport detoxification protein BACvac02_3974 ENOG4105VPX protein, conserved in bacteria BACvac02_3976 ENOG4105NIV Esterase BACvac02_3977 ENOG4105E0A ABC, transporter BACvac02_3983 ENOG4105CGK Exodeoxyribonuclease III BACvac02_3985 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BACvac02_3986 ENOG4105D03 DNA-3-methyladenine glycosylase II BACvac02_3992 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_3994 ENOG4105BZU Histidine kinase BACvac02_3998 ENOG41067MG lrgb family BACvac02_4001 ENOG4107TTQ Alpha beta hydrolase fold BACvac02_4002 ENOG4107YEI lmbE family BACvac02_4007 ENOG4105F0V Cell wall hydrolase BACvac02_4008 ENOG4107R6R udp-galactopyranose mutase BACvac02_4009 ENOG4105E0M Sulfatase BACvac02_4010 ENOG410890F Dynamin family BACvac02_4012 ENOG4107QHE Choloylglycine hydrolase BACvac02_4017 ENOG4105DA5 (ABC) transporter BACvac02_4022 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BACvac02_4023 ENOG4105DQU oxidoreductase, subunit beta BACvac02_4024 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BACvac02_4025 ENOG4108IGT Dipeptidase BACvac02_4026 ENOG4105MCT stage V sporulation protein S BACvac02_4027 ENOG4105D48 metallophosphoesterase BACvac02_4032 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BACvac02_4033 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BACvac02_4036 ENOG4105XZV Protein of unknown function (DUF3243) BACvac02_4037 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BACvac02_4038 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BACvac02_4044 ENOG4108JQ9 ABC transporter BACvac02_4045 ENOG4105DIH basic membrane BACvac02_4046 ENOG4105FDP GntR family transcriptional regulator BACvac02_4047 ENOG4107QZI cell division protein FtsK BACvac02_4049 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BACvac02_4051 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BACvac02_4053 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BACvac02_4054 ENOG4108S0H Dipicolinic acid synthetase, b subunit BACvac02_4055 ENOG4105E35 Dipicolinate synthase subunit A BACvac02_4057 ENOG4105C1V Peptidase, M16 BACvac02_4060 ENOG4105DTN riboflavin biosynthesis protein ribF BACvac02_4063 ENOG4105W7A Protein of unknown function (DUF503) BACvac02_4065 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BACvac02_4066 ENOG4105CHV Transcription elongation factor NusA BACvac02_4068 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BACvac02_4071 ENOG4105DZP Membrane-associated zinc metalloprotease BACvac02_4072 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BACvac02_4073 ENOG4105KNE Phosphatidate cytidylyltransferase BACvac02_4074 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BACvac02_4083 ENOG4108HE4 integrase family BACvac02_4085 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BACvac02_4087 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BACvac02_4090 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BACvac02_4095 ENOG4105VB6 UPF0109 protein BACvac02_4100 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BACvac02_4101 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BACvac02_4104 ENOG4105CHR reductase BACvac02_4105 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BACvac02_4108 ENOG4105CB5 ATP-dependent DNA helicase recG BACvac02_4109 ENOG4105DP4 dak2 domain fusion protein ylov BACvac02_4110 ENOG4108ZAA Alkaline-shock protein BACvac02_4112 ENOG4105FJ0 thiamine BACvac02_4113 ENOG4105DJV ribulose-phosphate 3-epimerase BACvac02_4114 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BACvac02_4115 ENOG4105D9P serine threonine protein kinase BACvac02_4116 ENOG4105D9P serine threonine protein kinase BACvac02_4117 ENOG4108ZF3 Phosphatase BACvac02_4119 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BACvac02_4121 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BACvac02_4122 ENOG4105C25 Primosomal protein n' BACvac02_4123 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BACvac02_4127 ENOG4105DSJ YicC domain protein BACvac02_4129 ENOG4105F23 Fibronectin-binding protein BACvac02_4130 ENOG4105F23 Fibronectin-binding protein BACvac02_4131 ENOG4105DC7 peptidase M24 BACvac02_4141 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BACvac02_4149 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BACvac02_4151 ENOG4105DBK s4 domain protein BACvac02_4153 ENOG4105DFA alanine racemase domain protein BACvac02_4154 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BACvac02_4155 ENOG4105WR5 sporulation protein, YlmC YmxH family BACvac02_4157 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4158 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4160 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BACvac02_4161 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BACvac02_4162 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BACvac02_4163 ENOG4105D4A Cell wall formation (By similarity) BACvac02_4164 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BACvac02_4165 ENOG4105CNI cell division protein FtsW BACvac02_4166 ENOG4105CNI cell division protein FtsW BACvac02_4169 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BACvac02_4170 ENOG4105CJN penicillin-binding protein BACvac02_4171 ENOG4105CJN penicillin-binding protein BACvac02_4172 ENOG4105CJN penicillin-binding protein BACvac02_4173 ENOG4105CJN penicillin-binding protein BACvac02_4174 ENOG4105CJN penicillin-binding protein BACvac02_4175 ENOG41068DC Essential cell division protein (By similarity) BACvac02_4183 ENOG4105KNH Nucleic acid-binding protein BACvac02_4193 ENOG4105XSJ toxin secretion phage lysis holin BACvac02_4212 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BACvac02_4214 ENOG4105CAR Terminase, large subunit BACvac02_4231 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BACvac02_4233 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4242 ENOG4108IMY Transcriptional regulator BACvac02_4249 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BACvac02_4251 ENOG41063PX domain protein BACvac02_4252 ENOG4105D78 K07001 NTE family protein BACvac02_4253 ENOG4105H20 Sporulation integral membrane protein YlbJ BACvac02_4255 ENOG4106H78 methyltransferase BACvac02_4261 ENOG4107TB6 phosphoglycerate mutase BACvac02_4265 ENOG4106UY4 Inherit from COG: Scp-like extracellular BACvac02_4275 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BACvac02_4276 ENOG4105CNI cell division protein FtsW BACvac02_4277 ENOG4105CNI cell division protein FtsW BACvac02_4280 ENOG4108IAB Phoh family BACvac02_4285 ENOG4105QA2 BACvac02_4286 ENOG4105CI3 gtp-binding protein typa BACvac02_4287 ENOG4105CI3 gtp-binding protein typa BACvac02_4289 ENOG4105ECY inositol monophosphatase BACvac02_4293 ENOG4105CXN decarboxylase BACvac02_4301 ENOG4105C7S Dehydrogenase BACvac02_4302 ENOG4105CPP Dehydrogenase, E1 component BACvac02_4305 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BACvac02_4306 ENOG4108X4Q Hydrolase BACvac02_4308 ENOG4105CN5 Metallo-Beta-Lactamase BACvac02_4309 ENOG4105CN5 Metallo-Beta-Lactamase BACvac02_4310 ENOG4107ZYR domain protein BACvac02_4317 ENOG4108XRC Protein of unknown function (DUF458) BACvac02_4319 ENOG4107IN1 Protein of unknown function (DUF1797) BACvac02_4322 ENOG4105EPM Diguanylate phosphodiesterase BACvac02_4323 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BACvac02_4325 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BACvac02_4327 ENOG4105UIN BACvac02_4341 ENOG4108HGU Histidine kinase BACvac02_4342 ENOG4108HGU Histidine kinase BACvac02_4344 ENOG4105CHM Aminotransferase BACvac02_4345 ENOG4105FKQ transcriptional regulator BACvac02_4346 ENOG4105EG2 ABC transporter, permease BACvac02_4348 ENOG4107FKK extracellular solute-binding protein family 1 BACvac02_4350 ENOG4105CG3 alpha amylase, catalytic region BACvac02_4351 ENOG4105CG3 alpha amylase, catalytic region BACvac02_4360 ENOG4105CHU acetyl-coa acetyltransferase BACvac02_4368 ENOG4105K7K Transcriptional regulator BACvac02_4369 ENOG4105DTD Dehydrogenase BACvac02_4371 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BACvac02_4373 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BACvac02_4378 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BACvac02_4381 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BACvac02_4382 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BACvac02_4383 ENOG4105BZU Histidine kinase BACvac02_4387 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BACvac02_4390 ENOG4105CID antiterminator BACvac02_4392 ENOG4105FDP GntR family transcriptional regulator BACvac02_4394 ENOG4105CE4 GlcNAc 6-P deacetylase BACvac02_4402 ENOG4107ZE5 PPIases accelerate the folding of proteins BACvac02_4403 ENOG4105PTM secreted protein BACvac02_4404 ENOG4105J7I hydrolase BACvac02_4408 ENOG4105CZ3 stage V sporulation protein ad BACvac02_4409 ENOG41090VF Stage v sporulation protein ac BACvac02_4414 ENOG4105C8J )-transporter BACvac02_4415 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4417 ENOG41082AN stage II sporulation protein BACvac02_4418 ENOG4105DZ1 carboxypeptidase BACvac02_4420 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BACvac02_4421 ENOG4105DVE abc transporter atp-binding protein BACvac02_4430 ENOG4105D7N magnesium and cobalt transport protein CorA BACvac02_4435 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BACvac02_4437 ENOG4105I3K Ferric uptake regulator, Fur family BACvac02_4438 ENOG4105MZ9 stage II sporulation protein m BACvac02_4442 ENOG4105CPC Aldo Keto reductase BACvac02_4444 ENOG4105RHY Pfam:UPF0157 BACvac02_4449 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BACvac02_4451 ENOG4105ETE Transcriptional regulator (LacI family BACvac02_4452 ENOG4108YM7 Gcn5-related n-acetyltransferase BACvac02_4456 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BACvac02_4457 ENOG4108R6K riboflavin synthase, subunit alpha BACvac02_4461 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BACvac02_4462 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BACvac02_4463 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BACvac02_4464 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BACvac02_4466 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BACvac02_4469 ENOG4105DFD Na H antiporter BACvac02_4470 ENOG4105CGH 5'-nucleotidase BACvac02_4478 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BACvac02_4479 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BACvac02_4482 ENOG4108IXY short-chain dehydrogenase reductase BACvac02_4485 ENOG4105II7 pyrroline-5-carboxylate reductase BACvac02_4486 ENOG4105EJQ L-serine dehydratase BACvac02_4491 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BACvac02_4492 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BACvac02_4493 ENOG4105D9U N-acetyltransferase BACvac02_4496 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BACvac02_4497 ENOG4108QEG Membrane BACvac02_4498 ENOG4105CDA abc transporter atp-binding protein BACvac02_4499 ENOG4105E5Q amino acid AbC transporter BACvac02_4500 ENOG4108HW3 (ABC) transporter BACvac02_4503 ENOG4105G7B Protein of unknown function (DUF2992) BACvac02_4504 ENOG4105E09 nadh pyrophosphatase BACvac02_4506 ENOG4105C7S Dehydrogenase BACvac02_4507 ENOG4105CPP Dehydrogenase, E1 component BACvac02_4511 ENOG4107RDP Dehydrogenase BACvac02_4513 ENOG4108JUB Transcriptional regulator BACvac02_4514 ENOG4108JUB Transcriptional regulator BACvac02_4516 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BACvac02_4519 ENOG4107QQR Sporulation BACvac02_4520 ENOG4105S1Z Stage IV sporulation protein B BACvac02_4521 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BACvac02_4523 ENOG4105DX0 Hemolysin A BACvac02_4525 ENOG4105CTB Polyprenyl synthetase BACvac02_4530 ENOG4108ZSR alkaline shock protein BACvac02_4531 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BACvac02_4535 ENOG410644B Stage III sporulation protein af BACvac02_4537 ENOG4105KQ4 Stage iii sporulation protein ad BACvac02_4538 ENOG4108CQH stage III sporulation protein AC BACvac02_4539 ENOG4105KR5 Stage iii sporulation protein BACvac02_4540 ENOG4105CD2 stage iii sporulation protein aa BACvac02_4541 ENOG4105CD2 stage iii sporulation protein aa BACvac02_4545 ENOG4105DC7 peptidase M24 BACvac02_4548 ENOG4105CBJ Metal-dependent enzyme BACvac02_4550 ENOG4107YBY Hydrolase BACvac02_4554 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BACvac02_4555 ENOG4105WZW rhodanese family BACvac02_4559 ENOG41080TC multidrug resistance protein BACvac02_4567 ENOG4105CJ1 ABC, transporter BACvac02_4568 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BACvac02_4574 ENOG4105C0D helicase BACvac02_4599 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BACvac02_4603 ENOG4105C28 cystathionine BACvac02_4604 ENOG4105C28 cystathionine BACvac02_4608 ENOG4105C5X domain protein BACvac02_4610 ENOG4105DKQ ROK family BACvac02_4612 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BACvac02_4615 ENOG4108UTW Plays a role in the regulation of phosphate uptake BACvac02_4616 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BACvac02_4617 ENOG4105E2Z phosphate ABC transporter (Permease BACvac02_4618 ENOG4105C8U phosphate abc transporter BACvac02_4619 ENOG4105PWN phosphate abc transporter BACvac02_4620 ENOG4107RF6 penicillin-binding protein BACvac02_4622 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BACvac02_4627 ENOG4105N80 Ferric uptake regulator, Fur family BACvac02_4629 ENOG4105FDK ABC transporter BACvac02_4630 ENOG4108JYZ YitT family BACvac02_4631 ENOG41069ZM Protein of unknown function (DUF2624) BACvac02_4637 ENOG4105EGD dinuclear metal center protein, YbgI family BACvac02_4640 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4641 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BACvac02_4648 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BACvac02_4649 ENOG4105KG3 cytidine deaminase BACvac02_4650 ENOG4107YR5 Diacylglycerol kinase BACvac02_4652 ENOG4105CTJ Metal Dependent Phosphohydrolase BACvac02_4653 ENOG4105C9A Phoh family BACvac02_4656 ENOG41068P3 sporulation protein YqfC BACvac02_4657 ENOG4105KTH gatB Yqey BACvac02_4659 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BACvac02_4660 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BACvac02_4664 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BACvac02_4666 ENOG4105CSA Coproporphyrinogen iii oxidase BACvac02_4667 ENOG4105KVH Transcriptional regulator BACvac02_4672 ENOG4105TQK DNA polymerase iii, delta' subunit BACvac02_4674 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BACvac02_4675 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BACvac02_4677 ENOG4108UK2 deaminase BACvac02_4678 ENOG4105KQC Competence protein BACvac02_4680 ENOG4105DXX methyltransferase BACvac02_4682 ENOG4108WF2 Metal Dependent Phosphohydrolase BACvac02_4684 ENOG410812S Rna-binding protein BACvac02_4686 ENOG4105CQW ribosome biogenesis GTPase YqeH BACvac02_4687 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BACvac02_4690 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_4693 ENOG4105WDJ 50S ribosomal protein L33 BACvac02_4694 ENOG4108TVJ Nitroreductase BACvac02_4697 ENOG4105G6Z alkaline phosphatase BACvac02_4700 ENOG4108MUZ hydrolase BACvac02_4707 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BACvac02_4708 ENOG4105MIR Phenylalanine 4-monooxygenase BACvac02_4710 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_4711 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_4720 ENOG4105S6R Iron-hydroxamate transporter permease subunit BACvac02_4721 ENOG4108V5C ABC transporter BACvac02_4723 ENOG4108EKI Dehydrogenase BACvac02_4724 ENOG4105C28 cystathionine BACvac02_4730 ENOG4107XRG penicillin-binding protein BACvac02_4733 ENOG4105CFP Peptidase U32 BACvac02_4734 ENOG4105XYU peptidase (U32 family) BACvac02_4735 ENOG4108VQJ O-methyltransferase BACvac02_4736 ENOG4105HHA aminodeoxychorismate lyase BACvac02_4740 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BACvac02_4743 ENOG4105C02 permease BACvac02_4746 ENOG41060CR BACvac02_4747 ENOG4105C7H Helicase, RecD TraA family BACvac02_4749 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BACvac02_4750 ENOG4105C3J Cysteine desulfurase BACvac02_4752 ENOG4105D1H recombination factor protein RarA BACvac02_4753 ENOG4108VCI transcription factor, rsfa family BACvac02_4754 ENOG4105CUZ uba thif-type nad fad binding protein BACvac02_4756 ENOG4105CUT histidyl-tRNA synthetase BACvac02_4757 ENOG4105CUT histidyl-tRNA synthetase BACvac02_4761 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BACvac02_4763 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BACvac02_4764 ENOG41076HS cation diffusion facilitator family transporter BACvac02_4765 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BACvac02_4767 ENOG4105CKP Polysaccharide Biosynthesis Protein BACvac02_4768 ENOG4108QG2 Membrane BACvac02_4770 ENOG4105VIE preprotein translocase, subunit YajC BACvac02_4773 ENOG41061AI Protein of unknown function (DUF2905) BACvac02_4776 ENOG4108HUF Transporter BACvac02_4780 ENOG41082BM Transcriptional regulator, arsr family BACvac02_4786 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BACvac02_4787 ENOG4108IYU L-aspartate oxidase BACvac02_4790 ENOG4108RPX mosc domain containing protein BACvac02_4791 ENOG4105CQC Prephenate dehydratase BACvac02_4796 ENOG4105EWM Histidine kinase BACvac02_4799 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BACvac02_4802 ENOG4105X36 (ribosomal) protein BACvac02_4804 ENOG4105C03 ribonuclease BACvac02_4807 ENOG4107QMS site-determining protein BACvac02_4810 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BACvac02_4811 ENOG4105DFF Rod shape-determining protein mreb BACvac02_4815 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BACvac02_4816 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BACvac02_4818 ENOG41068KH stage VI sporulation protein D BACvac02_4820 ENOG4105D52 delta-aminolevulinic acid dehydratase BACvac02_4825 ENOG4105K56 Transcriptional regulator BACvac02_4829 ENOG4108IUQ atp-dependent protease BACvac02_4834 ENOG4108QCI YvbH-like oligomerisation region BACvac02_4838 ENOG4105M59 Phosphodiesterase, mj0936 family BACvac02_4841 ENOG4108XJQ germination protein BACvac02_4843 ENOG4108PCX Major Facilitator BACvac02_4846 ENOG4105KBX Transcriptional regulator, TetR family BACvac02_4849 ENOG4105PFC Transcriptional regulator BACvac02_4852 ENOG4105DZC cytosine deaminase BACvac02_4853 ENOG4105DZC cytosine deaminase BACvac02_4854 ENOG4105DZC cytosine deaminase BACvac02_4855 ENOG4105DEF Extracellular solute-binding protein, family 5 BACvac02_4857 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BACvac02_4860 ENOG4108JQ7 (ABC) transporter BACvac02_4861 ENOG4108JQ7 (ABC) transporter BACvac02_4862 ENOG4108HRK Histidine kinase BACvac02_4863 ENOG4105DY9 regulatoR BACvac02_4868 ENOG4108JCI Transcriptional regulator BACvac02_4870 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BACvac02_4871 ENOG4108Z40 Transcriptional regulator BACvac02_4872 ENOG4105RHA ABC transporter, permease BACvac02_4873 ENOG4108IUX (ABC) transporter BACvac02_4875 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BACvac02_4876 ENOG4105ER2 Ompa motb domain protein BACvac02_4878 ENOG4105E14 MotA TolQ exbB proton channel BACvac02_4879 ENOG4108VXD carboxy-peptidase BACvac02_4881 ENOG4105E33 succinate dehydrogenase BACvac02_4883 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BACvac02_4886 ENOG4105K63 Thioredoxin BACvac02_4887 ENOG4105C10 Electron transfer flavoprotein BACvac02_4888 ENOG4105BZJ Electron transfer flavoprotein BACvac02_4889 ENOG41060WC Enoyl-CoA hydratase BACvac02_4890 ENOG4107Z3H Transcriptional regulator, TetR family BACvac02_4891 ENOG4105CEY Amp-dependent synthetase and ligase BACvac02_4894 ENOG4105J76 Periplasmic binding protein BACvac02_4895 ENOG4105S6R Iron-hydroxamate transporter permease subunit BACvac02_4903 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_4905 ENOG4105DR4 Methyltransferase BACvac02_4908 ENOG4105KFN sortase, SrtB family BACvac02_4909 ENOG4105E0A ABC, transporter BACvac02_4912 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BACvac02_4914 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BACvac02_4921 ENOG4105DCG PHP domain protein BACvac02_4928 ENOG4105C5S asparaginyl-tRNA synthetase BACvac02_4929 ENOG4105C5S asparaginyl-tRNA synthetase BACvac02_4930 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BACvac02_4931 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BACvac02_4933 ENOG4108RWN rrna methyltransferase BACvac02_4941 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_4942 ENOG4105C0R drug resistance transporter emrb qaca subfamily BACvac02_4943 ENOG4105CW7 secretion protein, HlyD family BACvac02_4944 ENOG4105CW7 secretion protein, HlyD family BACvac02_4945 ENOG4108JGH Tetr family transcriptional regulator BACvac02_4946 ENOG4105CN9 Peptidase m42 family protein BACvac02_4950 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BACvac02_4951 ENOG4105C22 threonyL-tRNA synthetase BACvac02_4952 ENOG4108TDW sporulation protein YtxC BACvac02_4956 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BACvac02_4957 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BACvac02_4958 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BACvac02_4960 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BACvac02_4961 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BACvac02_4962 ENOG4105C2M dna polymerase I BACvac02_4963 ENOG4105BZU Histidine kinase BACvac02_4964 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_4968 ENOG4108HMX isocitrate dehydrogenase (NADP) BACvac02_4969 ENOG4105BZN citrate synthase BACvac02_4971 ENOG4108REF Sporulation integral membrane protein ytvi BACvac02_4972 ENOG4105FS0 cytoplasmic membrane protein BACvac02_4977 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BACvac02_4978 ENOG4105C6K Malic enzyme BACvac02_4979 ENOG4105C0B DNA polymerase III (alpha subunit) BACvac02_4980 ENOG4105VV2 BACvac02_4982 ENOG4105SFS phosphoesterase RecJ domain protein BACvac02_4989 ENOG4105DC7 peptidase M24 BACvac02_4995 ENOG4105Z7P Acetyltransferase (GNAT) family BACvac02_4996 ENOG41082W1 Cupin 2, conserved barrel domain protein BACvac02_4998 ENOG4105VZ8 Transcriptional regulator BACvac02_5002 ENOG4107YZX Universal stress protein BACvac02_5011 ENOG4108JYZ YitT family BACvac02_5015 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BACvac02_5017 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BACvac02_5018 ENOG4105KBJ sporulation protein ytfj BACvac02_5021 ENOG4105EFZ amidohydrolase BACvac02_5023 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BACvac02_5029 ENOG4106KR7 LysR family Transcriptional regulator BACvac02_5034 ENOG4105C28 cystathionine BACvac02_5038 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BACvac02_5040 ENOG4105EMN RNA polymerase sigma factor BACvac02_5043 ENOG4105F1V Acetoin utilization protein BACvac02_5044 ENOG4105W87 Cbs domain BACvac02_5045 ENOG4105DGU Histone deacetylase BACvac02_5047 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BACvac02_5049 ENOG4107SNB ankyrin repeat protein YahD BACvac02_5050 ENOG4105EP9 oxidoreductase BACvac02_5056 ENOG4105ETE Transcriptional regulator (LacI family BACvac02_5060 ENOG4105C88 aminopeptidase BACvac02_5069 ENOG4108VDD TRNA binding domain protein BACvac02_5075 ENOG4105C8F Beta-lactamase domain protein BACvac02_5078 ENOG4108V15 phosphotransferase enzyme family BACvac02_5079 ENOG4108IUM Glycogen debranching enzyme BACvac02_5083 ENOG4105YW5 deoR family transcriptional regulator BACvac02_5086 ENOG4105CBX hi0933 family BACvac02_5093 ENOG4108VJ1 Transcriptional regulator (CarD family BACvac02_5094 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BACvac02_5095 ENOG4105CSC Glucose uptake protein BACvac02_5098 ENOG4108ZAF Molybdopterin BACvac02_5099 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BACvac02_5100 ENOG4105CVM Molybdenum cofactor synthesis domain protein BACvac02_5102 ENOG4105D06 uba thif-type nad fad binding protein BACvac02_5103 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BACvac02_5104 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BACvac02_5108 ENOG41085GJ domain protein BACvac02_5110 ENOG4105DWV Homoserine O-trans-acetylase BACvac02_5112 ENOG4108B31 Spore germination protein BACvac02_5119 ENOG410605W Major Facilitator BACvac02_5120 ENOG410605W Major Facilitator BACvac02_5121 ENOG4107S91 Sodium hydrogen exchanger BACvac02_5122 ENOG4105NCW Trka-c domain protein BACvac02_5126 ENOG4105C19 ABC transporter BACvac02_5130 ENOG4105N5T Radical SAM Protein BACvac02_5132 ENOG4105DA5 (ABC) transporter BACvac02_5139 ENOG4105E8V Alpha Beta Hydrolase Fold protein BACvac02_5140 ENOG4108Z0R Transferase BACvac02_5141 ENOG4105YVM Phosphoesterase, PA-phosphatase related BACvac02_5142 ENOG4105BZF Glycosyl transferase (Group 1 BACvac02_5144 ENOG4108RIR Molybdenum cofactor biosynthesis protein BACvac02_5154 ENOG4105EGD dinuclear metal center protein, YbgI family BACvac02_5155 ENOG4105BZU Histidine kinase BACvac02_5156 ENOG4105BZU Histidine kinase BACvac02_5158 ENOG4107S9D Alpha beta hydrolase BACvac02_5159 ENOG4107T7U Sulfatase BACvac02_5164 ENOG4105D2X ABC transporter substrate-binding protein BACvac02_5168 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BACvac02_5175 ENOG4108V2W Carbonate dehydratase BACvac02_5176 ENOG4105C4M (Ubiquinol oxidase) subunit I BACvac02_5177 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BACvac02_5186 ENOG41087YS Phage shock protein A BACvac02_5191 ENOG4105BZU Histidine kinase BACvac02_5192 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_5196 ENOG4108UGV hypoxanthine phosphoribosyltransferase BACvac02_5197 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BACvac02_5203 ENOG4107ZTW SNARE associated Golgi BACvac02_5206 ENOG4105C19 ABC transporter BACvac02_5207 ENOG41086D8 Transcriptional regulator BACvac02_5218 ENOG4105C6Z Gluconate BACvac02_5219 ENOG4105FDP GntR family transcriptional regulator BACvac02_5223 ENOG41069H0 dihydroorotase EC 3.5.2.3 BACvac02_5229 ENOG4105DTQ mandelate racemase muconate lactonizing BACvac02_5231 ENOG4108IPT Naphthoate synthase BACvac02_5232 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BACvac02_5233 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BACvac02_5234 ENOG4105E4F Isochorismate synthase BACvac02_5235 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BACvac02_5237 ENOG4105VEQ Cold shock protein BACvac02_5241 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BACvac02_5243 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BACvac02_5246 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BACvac02_5265 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BACvac02_5274 ENOG4105KT7 mgtC SapB transporter BACvac02_5275 ENOG4107PBV potassium channel BACvac02_5277 ENOG4107QYV phosphohexose isomerase BACvac02_5278 ENOG4105WG9 Conserved Protein BACvac02_5280 ENOG4105CHM Aminotransferase BACvac02_5281 ENOG4108ZB6 transcriptional regulator AsnC family BACvac02_5282 ENOG4105C5I Dehydrogenase BACvac02_5283 ENOG4108MUZ hydrolase BACvac02_5285 ENOG4105C87 Aminotransferase class I and II BACvac02_5288 ENOG4105Y38 Kinase-associated protein B BACvac02_5290 ENOG4107R3E Citrate transporter BACvac02_5293 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BACvac02_5294 ENOG4105KA0 thioesterase Superfamily protein BACvac02_5298 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BACvac02_5302 ENOG41069ER domain protein BACvac02_5305 ENOG4105CEP NADH dehydrogenase BACvac02_5311 ENOG4105EWC Purine nucleoside phosphorylase BACvac02_5315 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BACvac02_5320 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BACvac02_5321 ENOG4105C4B ABC transporter, permease BACvac02_5322 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BACvac02_5331 ENOG41083MR nifu domain-containing protein BACvac02_5334 ENOG4108W5N phosphatidylglycerophosphatase a BACvac02_5336 ENOG4105DYS nad(p)h dehydrogenase (quinone) BACvac02_5337 ENOG4105D4U had-superfamily hydrolase, subfamily iia BACvac02_5340 ENOG4105CBT Fructose-1,6-bisphosphatase BACvac02_5343 ENOG4105MMD transcriptional regulator BACvac02_5345 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BACvac02_5346 ENOG4107TXC Transcriptional regulator BACvac02_5347 ENOG41090T1 Membrane BACvac02_5352 ENOG4105FAA peptidase M23 BACvac02_5354 ENOG4105KZD Domain of unknown function (DUF1805) BACvac02_5360 ENOG4105DIW FeS assembly protein SUFB BACvac02_5361 ENOG4108UNV SUF system FeS assembly protein, NifU family BACvac02_5362 ENOG4105C9B Cysteine desulfurase BACvac02_5363 ENOG4105JRK feS assembly protein SufD BACvac02_5364 ENOG4105C3K feS assembly ATPase SufC BACvac02_5366 ENOG4105D01 (LipO)protein BACvac02_5367 ENOG4105D01 (LipO)protein BACvac02_5368 ENOG4108UMI ABC transporter, permease BACvac02_5375 ENOG41080E8 Transcriptional regulator, Spx MgsR family BACvac02_5383 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BACvac02_5388 ENOG4108W8B Beta-lactamase domain protein BACvac02_5389 ENOG4105C1G acyl-Coa dehydrogenase BACvac02_5391 ENOG4105CHU acetyl-coa acetyltransferase BACvac02_5395 ENOG4105DZ1 carboxypeptidase BACvac02_5399 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BACvac02_5402 ENOG4108SUT Major Facilitator Superfamily BACvac02_5403 ENOG4107R7I amino acid BACvac02_5405 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BACvac02_5407 ENOG4107AYK membrAne BACvac02_5414 ENOG4107ZTW SNARE associated Golgi BACvac02_5416 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BACvac02_5417 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_5418 ENOG4105BZU Histidine kinase BACvac02_5420 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BACvac02_5423 ENOG4105VG1 fes assembly suf system protein BACvac02_5424 ENOG4105D4Y metalloprotease BACvac02_5428 ENOG4107S91 Sodium hydrogen exchanger BACvac02_5429 ENOG4105NCW Trka-c domain protein BACvac02_5430 ENOG4105NCW Trka-c domain protein BACvac02_5432 ENOG4108RMU ferritin dps family protein BACvac02_5436 ENOG4108URH decarboxylase BACvac02_5441 ENOG4105D9N nucleoside BACvac02_5442 ENOG4105D9N nucleoside BACvac02_5445 ENOG4108RYK Nad-dependent epimerase dehydratase BACvac02_5450 ENOG4105CV8 reductase BACvac02_5451 ENOG4105F27 Major Facilitator BACvac02_5452 ENOG4105KVH Transcriptional regulator BACvac02_5455 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BACvac02_5456 ENOG4105D4A Cell wall formation (By similarity) BACvac02_5458 ENOG4105C8Q Methyl-accepting chemotaxis BACvac02_5460 ENOG4105WMR Protein CrcB homolog BACvac02_5463 ENOG4108MK9 spermidine N(1)-acetyltransferase BACvac02_5464 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BACvac02_5467 ENOG4108IPW abc transporter atp-binding protein BACvac02_5468 ENOG4105CM4 permease protein BACvac02_5474 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BACvac02_5477 ENOG4105XZU Preprotein translocase, subunit SecG BACvac02_5478 ENOG41067MG lrgb family BACvac02_5499 ENOG4105EFC phage portal protein HK97 family BACvac02_5506 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BACvac02_5508 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BACvac02_5509 ENOG4105CP7 Triose-phosphate isomerase BACvac02_5515 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BACvac02_5519 ENOG41090VF Stage v sporulation protein ac BACvac02_5520 ENOG4105CZ3 stage V sporulation protein ad BACvac02_5523 ENOG4105H67 Protein of unknown function (DUF421) BACvac02_5524 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BACvac02_5525 ENOG4105KRI phosphocarrier protein (HPr BACvac02_5527 ENOG4105CHW UPF0052 protein BACvac02_5529 ENOG4108Z4K mutator MutT protein BACvac02_5531 ENOG4105C3M thioredoxin reductase BACvac02_5533 ENOG4108S4C acetyltransferase BACvac02_5537 ENOG41086DT Membrane protein of unknown function BACvac02_5539 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BACvac02_5540 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BACvac02_5541 ENOG4105D7V transposase BACvac02_5544 ENOG4107TXC Transcriptional regulator BACvac02_5550 ENOG4105DUM transcriptional regulator, lysR family BACvac02_5552 ENOG4108WS4 fmn reductase BACvac02_5555 ENOG4105BZ1 (ABC) transporter BACvac02_5556 ENOG4105BZ1 (ABC) transporter BACvac02_5558 ENOG4105CN1 protease BACvac02_5559 ENOG4105CRP Part of the ABC transporter FtsEX involved in BACvac02_5560 ENOG4105CAK Cell division ATP-binding protein ftsE BACvac02_5562 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BACvac02_5563 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BACvac02_5564 ENOG4105MS2 ribosomal subunit Interface protein BACvac02_5566 ENOG4105VEQ Cold shock protein BACvac02_5567 ENOG41081UC Inherit from COG: Competence protein BACvac02_5570 ENOG4105KVH Transcriptional regulator BACvac02_5572 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BACvac02_5573 ENOG4108KGH TRANSCRIPTIONal BACvac02_5574 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BACvac02_5575 ENOG4105C6Y Udp-glucose 6-dehydrogenase BACvac02_5577 ENOG4105ESV Glycosyl transferase, family 4 BACvac02_5579 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BACvac02_5582 ENOG410901P UPF0249 protein BACvac02_5583 ENOG4105F8D glycoside hydrolase family 4 BACvac02_5584 ENOG4105VCP PTS System BACvac02_5585 ENOG4105CK1 PTS System BACvac02_5587 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BACvac02_5588 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BACvac02_5589 ENOG4105VCP PTS System BACvac02_5591 ENOG4105VZJ PTS System BACvac02_5594 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BACvac02_5595 ENOG4105ECB domain protein BACvac02_5596 ENOG4105ECB domain protein BACvac02_5597 ENOG4107RSM transcriptional regulator BACvac02_5598 ENOG4105C5Q Transcriptional regulator BACvac02_5606 ENOG4105DAA L-lactate BACvac02_5608 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BACvac02_5611 ENOG4105E0M Sulfatase BACvac02_5619 ENOG4107R8N Glycosyl transferase, family 2 BACvac02_5621 ENOG4105C94 Transporter BACvac02_5622 ENOG41069ER domain protein BACvac02_5628 ENOG4105KBK Zinc finger, swim domain protein BACvac02_5629 ENOG4105C0D helicase BACvac02_5630 ENOG4105C0D helicase BACvac02_5638 ENOG4107RBB ABC transporter, permease BACvac02_5639 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BACvac02_5640 ENOG4105C19 ABC transporter BACvac02_5644 ENOG4105CXY transporter BACvac02_5647 ENOG4105BZU Histidine kinase BACvac02_5648 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_5650 ENOG4105CMR udp-glucose 4-epimerase BACvac02_5653 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BACvac02_5654 ENOG4105EY8 ABC transporter BACvac02_5655 ENOG4105EY8 ABC transporter BACvac02_5667 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BACvac02_5670 ENOG4105FRN stage II sporulation protein BACvac02_5674 ENOG4105DY9 regulatoR BACvac02_5679 ENOG4106778 Protein of unknown function (DUF1146) BACvac02_5680 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BACvac02_5681 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BACvac02_5682 ENOG4105C8S subunit m BACvac02_5683 ENOG4105D65 subunit l BACvac02_5688 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BACvac02_5689 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BACvac02_5691 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BACvac02_5692 ENOG4105BZU Histidine kinase BACvac02_5703 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BACvac02_5704 ENOG41062M3 atp synthase BACvac02_5710 ENOG4108YZG isomerase BACvac02_5711 ENOG4107WAU Protein tyrosine phosphatase BACvac02_5713 ENOG4108VGI doxx family BACvac02_5714 ENOG4107XC4 flavin reductase domain protein, FMN-binding BACvac02_5717 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BACvac02_5719 ENOG4108ZXQ stage ii sporulation protein r BACvac02_5720 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BACvac02_5721 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BACvac02_5722 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BACvac02_5724 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BACvac02_5725 ENOG4105CBT Fructose-1,6-bisphosphatase BACvac02_5726 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BACvac02_5733 ENOG4105C1G acyl-Coa dehydrogenase BACvac02_5734 ENOG4105C1G acyl-Coa dehydrogenase BACvac02_5735 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BACvac02_5738 ENOG4105DF6 Fe-S oxidoreductase BACvac02_5742 ENOG4105BZU Histidine kinase BACvac02_5743 ENOG4105BZU Histidine kinase BACvac02_5748 ENOG4105BZU Histidine kinase BACvac02_5749 ENOG4105KCT ABC transporter BACvac02_5750 ENOG4108M15 ABC transporter BACvac02_5751 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BACvac02_5755 ENOG4105IIU Aminopeptidase BACvac02_5759 ENOG4105EMN RNA polymerase sigma factor BACvac02_5761 ENOG410684U Domain of unknown function (DUF1934) BACvac02_5766 ENOG4105CYW agmatinase BACvac02_5768 ENOG4105DXB Major Facilitator superfamily BACvac02_5769 ENOG4107SWG transcriptional regulator MERR family BACvac02_5770 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BACvac02_5771 ENOG4105BZ4 penicillin-binding protein BACvac02_5773 ENOG4108XFG YwhD family BACvac02_5774 ENOG4108Z4T Peptidase M50 BACvac02_5775 ENOG4108Z4T Peptidase M50 BACvac02_5776 ENOG41069HH 4-oxalocrotonate tautomerase BACvac02_5777 ENOG4105DCI Phosphohydrolase BACvac02_5778 ENOG4108MES Periplasmic binding protein BACvac02_5779 ENOG4105E0A ABC, transporter BACvac02_5780 ENOG4105EHG Permease protein BACvac02_5781 ENOG4105DQ5 transport system permease protein BACvac02_5782 ENOG4105DQ5 transport system permease protein BACvac02_5784 ENOG4108VCI transcription factor, rsfa family BACvac02_5787 ENOG4108IJ2 phosphate acetyltransferase BACvac02_5791 ENOG4108VKI Cell wall hydrolase BACvac02_5795 ENOG4107SVH Potassium channel protein BACvac02_5797 ENOG410667J hydrolase BACvac02_5798 ENOG4105VCH membrane BACvac02_5800 ENOG4108TU7 Inherit from COG: (ABC) transporter BACvac02_5801 ENOG4105CJ1 ABC, transporter BACvac02_5802 ENOG41090WU lipolytic protein G-D-S-L family BACvac02_5805 ENOG4105D6E homoserine dehydrogenase BACvac02_5810 ENOG4108Y4K DNA-binding transcriptional activator BACvac02_5812 ENOG4105WH1 Two component transcriptional regulator luxr family BACvac02_5813 ENOG4105BZU Histidine kinase BACvac02_5815 ENOG4105BZU Histidine kinase BACvac02_5816 ENOG4105DWF phosphomethylpyrimidine kinase BACvac02_5817 ENOG4105BZU Histidine kinase BACvac02_5818 ENOG4105VCD cytoplasmic protein BACvac02_5819 ENOG4105D22 carbon starvation protein BACvac02_5820 ENOG4105DY9 regulatoR BACvac02_5821 ENOG41079KZ Major Facilitator Superfamily BACvac02_5826 ENOG4105EN6 Membrane BACvac02_5827 ENOG4106YBV Methyl-accepting chemotaxis BACvac02_5829 ENOG4108S4H thioesterase Superfamily protein BACvac02_5831 ENOG4105JEU Glycosyl transferase, family 2 BACvac02_5832 ENOG4105C5H ABC transporter BACvac02_5836 ENOG4105CKK Glycosyl transferase, family 2 BACvac02_5837 ENOG41067SE Tetr family transcriptional regulator BACvac02_5839 ENOG4105E0X reductase BACvac02_5840 ENOG4106F5Q Membrane BACvac02_5843 ENOG4105DY9 regulatoR BACvac02_5844 ENOG4108HRK Histidine kinase BACvac02_5845 ENOG4107RGD Major Facilitator superfamily BACvac02_5848 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BACvac02_5850 ENOG4105IW1 AmiS UreI transporter BACvac02_5852 ENOG4105CMR udp-glucose 4-epimerase BACvac02_5853 ENOG4108UT2 hemolysin iii BACvac02_5855 ENOG4105C1J atp-dependent rna helicase BACvac02_5858 ENOG4105DPN Oligoendopeptidase f BACvac02_5862 ENOG4105C0H protease BACvac02_5863 ENOG4105Q2H domain protein BACvac02_5866 ENOG4105BZU Histidine kinase BACvac02_5867 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BACvac02_5873 ENOG4105CDU Replicative dna helicase BACvac02_5875 ENOG4105BZR domain protein BACvac02_5876 ENOG4108XMW Membrane BACvac02_5878 ENOG4108UUM single-stranded DNA-binding protein BACvac02_5880 ENOG4105C3G gtp-binding protein BACvac02_5881 ENOG4105D8X mechanosensitive ion channel BACvac02_5882 ENOG4108ZDA Sporulation protein YyaC BACvac02_5883 ENOG4105FA0 parb-like partition protein BACvac02_5884 ENOG4107QJE Chromosome Partitioning Protein BACvac02_5888 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BACvac02_5890 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins