locus-tag class description CEQ19_00025 ENOG4105ETU transcriptional activator (TenA CEQ19_00155 ENOG410667J hydrolase CEQ19_00165 ENOG4105BZU Histidine kinase CEQ19_00170 ENOG4107RF6 penicillin-binding protein CEQ19_00190 ENOG4108JJB ABC transporter CEQ19_00205 ENOG4108HGU Histidine kinase CEQ19_00220 ENOG4105CB2 alcohol dehydrogenase CEQ19_00225 ENOG4105CJN penicillin-binding protein CEQ19_00235 ENOG4105FQP Beta-lactamase CEQ19_00270 ENOG4108V4B ThiJ pfpI CEQ19_00310 ENOG4107Y80 Major Facilitator superfamily CEQ19_00330 ENOG4107VXM glycerophosphoryl diester phosphodiesterase CEQ19_00350 ENOG4107Y9U Membrane CEQ19_00390 ENOG4105FCD Major Facilitator CEQ19_00405 ENOG4105E09 nadh pyrophosphatase CEQ19_00410 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CEQ19_00415 ENOG4108Z4K mutator MutT protein CEQ19_00450 ENOG4108XI2 Domain of unknown function (DUF1963) CEQ19_00480 ENOG4105KWG Pfam:DUF1696 CEQ19_00515 ENOG4105PKS Excinuclease abc c subunit domain protein CEQ19_00560 ENOG4107VFR oxidoreductase CEQ19_00585 ENOG4105PAD Hydrolase CEQ19_00605 ENOG4105DY8 decarboxylase CEQ19_00620 ENOG4108IUM Glycogen debranching enzyme CEQ19_00645 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CEQ19_00655 ENOG4105FDR Membrane CEQ19_00690 ENOG4108V3A UPF0421 protein CEQ19_00710 ENOG4105MSI germination protein ypeb CEQ19_00730 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) CEQ19_00735 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) CEQ19_00740 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) CEQ19_00745 ENOG4107Z3H Transcriptional regulator, TetR family CEQ19_00780 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family CEQ19_00800 ENOG4105E98 transcriptional regulator DeoR family CEQ19_00820 ENOG41062ES Transcriptional regulator CEQ19_00845 ENOG4107QKR Dehydrogenase CEQ19_00855 ENOG4107RUY (E1 component), alpha subunit CEQ19_00865 ENOG4105E1F short-chain dehydrogenase reductase CEQ19_00870 ENOG4105RHY Pfam:UPF0157 CEQ19_00905 ENOG4107SQ8 Glycine betaine CEQ19_00910 ENOG4108IJ7 Glycine betaine CEQ19_00935 ENOG4105E66 phosphoriboisomerase A CEQ19_00940 ENOG41082BV acetyltransferase CEQ19_00945 ENOG4108M1A Chitin-binding protein CEQ19_00990 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 CEQ19_01040 ENOG4105EEM helicase CEQ19_01060 ENOG4105C9U ATP-dependent DNA helicase RecQ CEQ19_01115 ENOG4108M1A Chitin-binding protein CEQ19_01130 ENOG4105BZG amino acid carrier protein CEQ19_01135 ENOG4105C26 Dehydrogenase CEQ19_01140 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CEQ19_01145 ENOG4105CTU Proline racemase CEQ19_01150 ENOG4105CTU Proline racemase CEQ19_01155 ENOG41080HI glycine oxidase CEQ19_01195 ENOG4107T5V SNARE associated Golgi CEQ19_01210 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD CEQ19_01215 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) CEQ19_01230 ENOG4105DTQ mandelate racemase muconate lactonizing CEQ19_01280 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) CEQ19_01285 ENOG4105BZU Histidine kinase CEQ19_01325 ENOG4105DPN Oligoendopeptidase f CEQ19_01340 ENOG4105EPR degv family CEQ19_01385 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CEQ19_01390 ENOG4106K7D Major facilitator family transporter CEQ19_01410 ENOG4107BMA Transglycosylase associated protein CEQ19_01425 ENOG41089UC methyltransferase, type 11 CEQ19_01465 ENOG4105CHM Aminotransferase CEQ19_01545 ENOG4105C02 permease CEQ19_01560 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) CEQ19_01565 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CEQ19_01570 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein CEQ19_01595 ENOG4105E09 nadh pyrophosphatase CEQ19_01615 ENOG4108AQF aminoglycoside N(3)-acetyltransferase CEQ19_01670 ENOG4107VC0 DNA alkylation repair enzyme CEQ19_01685 ENOG4107VMI polysaccharide deacetylase CEQ19_01695 ENOG4108ZCF integral membrane protein CEQ19_01700 ENOG4105E0M Sulfatase CEQ19_01710 ENOG4105C5H ABC transporter CEQ19_01720 ENOG4105EYF MMPL domain protein CEQ19_01725 ENOG4105EYF MMPL domain protein CEQ19_01730 ENOG41082JN Transcriptional regulator CEQ19_01750 ENOG4105CIH Imidazole acetol-phosphate transaminase CEQ19_01755 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase CEQ19_01765 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase CEQ19_01815 ENOG41069ER domain protein CEQ19_01830 ENOG4105EMN RNA polymerase sigma factor CEQ19_01855 ENOG4105D4B ABC, transporter CEQ19_01865 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CEQ19_01875 ENOG4105DKT Transcriptional regulator CEQ19_01890 ENOG41061GT Aldolase CEQ19_01910 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) CEQ19_01940 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) CEQ19_01950 ENOG4105II7 pyrroline-5-carboxylate reductase CEQ19_01960 ENOG4107258 Transcriptional regulator CEQ19_01975 ENOG4105E0Y RtcB Protein CEQ19_01980 ENOG4105ECK Fatty Acid Desaturase CEQ19_01985 ENOG4105G6Z alkaline phosphatase CEQ19_01995 ENOG4105VMP Transcriptional regulator CEQ19_02010 ENOG41090T1 Membrane CEQ19_02020 ENOG4108WCX response regulator CEQ19_02030 ENOG41068WN CEQ19_02055 ENOG4105C7R Atpase associated with various cellular activities aaa_3 CEQ19_02085 ENOG4105CKK Glycosyl transferase, family 2 CEQ19_02110 ENOG4105CKK Glycosyl transferase, family 2 CEQ19_02120 ENOG4105C8Y Acetylornithine aminotransferase CEQ19_02165 ENOG4105C7R Atpase associated with various cellular activities aaa_3 CEQ19_02175 ENOG4108TVJ Nitroreductase CEQ19_02180 ENOG4105FS7 Transcriptional regulator CEQ19_02220 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family CEQ19_02235 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CEQ19_02270 ENOG4108XET gCN5-related N-acetyltransferase CEQ19_02350 ENOG410635A Membrane CEQ19_02355 ENOG4105KNA -acetyltransferase CEQ19_02360 ENOG4108IQI permease CEQ19_02370 ENOG4105F1N DNA alkylation repair CEQ19_02410 ENOG4107RF6 penicillin-binding protein CEQ19_02420 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CEQ19_02460 ENOG4105P4J Allophanate hydrolase, subunit 1 CEQ19_02465 ENOG4107258 Transcriptional regulator CEQ19_02475 ENOG4106N3A copper homeostasis protein cutc CEQ19_02485 ENOG4108ZRV stage ii sporulation protein p CEQ19_02490 ENOG4108ZHR arsR family transcriptional regulator CEQ19_02500 ENOG4105FDT acyl-CoA dehydrogenase CEQ19_02520 ENOG4105DWD nucleoside recognition domain protein CEQ19_02550 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CEQ19_02630 ENOG4105E2A Dehydrogenase CEQ19_02645 ENOG4108IJ0 Aspartate ammonia-lyase CEQ19_02650 ENOG4105HDK L-asparaginase CEQ19_02655 ENOG4108IMY Transcriptional regulator CEQ19_02665 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) CEQ19_02670 ENOG4105CUB amino acid CEQ19_02680 ENOG4105II7 pyrroline-5-carboxylate reductase CEQ19_02690 ENOG4105C6K Malic enzyme CEQ19_02710 ENOG4108Q8B Spore germination protein CEQ19_02735 ENOG4105CSV Glutaminase CEQ19_02770 ENOG4105CGH 5'-nucleotidase CEQ19_02775 ENOG4105CH6 catalase CEQ19_02785 ENOG4105CHJ isochorismatase hydrolase CEQ19_02815 ENOG41090MY MarR family Transcriptional regulator CEQ19_02855 ENOG4108606 TspO/MBR family CEQ19_02860 ENOG4105CVP deoxyribo-dipyrimidine photolyase CEQ19_02875 ENOG4108TWJ NADH dehydrogenase subunit 5 CEQ19_02880 ENOG4105GPN Uncharacterized conserved protein (DUF2294) CEQ19_02895 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CEQ19_02900 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) CEQ19_02910 ENOG4105DSE periplasmic solute binding protein CEQ19_02915 ENOG4105CC5 ABC transporter CEQ19_02920 ENOG4105DIK (ABC) transporter CEQ19_02950 ENOG4105D6J arsenicaL-resistance protein CEQ19_02955 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_02960 ENOG41085FC arsR family transcriptional regulator CEQ19_02975 ENOG4105F7F Chaperone CEQ19_02990 ENOG4105CHR reductase CEQ19_02995 ENOG4108YXU transcriptional regulator AsnC family CEQ19_03075 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) CEQ19_03085 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ19_03100 ENOG4105IIP Membrane CEQ19_03115 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_03120 ENOG41062D9 Histidine kinase CEQ19_03155 ENOG4105K6H D-cysteine desulfhydrase CEQ19_03185 ENOG4105VZ8 Transcriptional regulator CEQ19_03200 ENOG4108NNI Beta-lactamase domain-containing protein CEQ19_03205 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CEQ19_03215 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CEQ19_03220 ENOG4105JQZ Methyltransferase CEQ19_03235 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) CEQ19_03240 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) CEQ19_03260 ENOG4105BZU Histidine kinase CEQ19_03275 ENOG4108U05 Transcriptional regulator CEQ19_03295 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) CEQ19_03300 ENOG4105DJB Major Facilitator Superfamily CEQ19_03305 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) CEQ19_03310 ENOG4107QR9 Iron-sulfur cluster binding protein CEQ19_03320 ENOG4106P55 Transcriptional regulator CEQ19_03330 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CEQ19_03370 ENOG4105TRI Hydrolase CEQ19_03410 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CEQ19_03440 ENOG4107QJQ Mate efflux family protein CEQ19_03460 ENOG4105MZU cell filamentation protein CEQ19_03465 ENOG4105EQ0 Major Facilitator superfamily CEQ19_03470 ENOG4108JGH Tetr family transcriptional regulator CEQ19_03485 ENOG4105C44 Serine transporter CEQ19_03490 ENOG4105EJQ L-serine dehydratase CEQ19_03510 ENOG4108JPW Aminotransferase CEQ19_03525 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) CEQ19_03535 ENOG4105DVH amino acid CEQ19_03555 ENOG4108JQ1 Dehydrogenase CEQ19_03575 ENOG4108AEY RNA polymerase sigma factor CEQ19_03590 ENOG41082W1 Cupin 2, conserved barrel domain protein CEQ19_03600 ENOG410874W AraC family transcriptional regulator CEQ19_03650 ENOG4108ISG Major Facilitator CEQ19_03660 ENOG4107MII Sugar-specific transcriptional regulator TrmB CEQ19_03665 ENOG4105CZM Major Facilitator CEQ19_03685 ENOG4105DA5 (ABC) transporter CEQ19_03690 ENOG41069JR CEQ19_03700 ENOG4105RXJ CEQ19_03705 ENOG4105KPY Small multidrug resistance protein CEQ19_03710 ENOG4105KBX Transcriptional regulator, TetR family CEQ19_03725 ENOG4105CRW Short chain fatty acid transporter CEQ19_03735 ENOG4105DYS nad(p)h dehydrogenase (quinone) CEQ19_03765 ENOG4108JJB ABC transporter CEQ19_03770 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) CEQ19_03795 ENOG4108K8S endonuclease I CEQ19_03810 ENOG41067QW Transcriptional regulator CEQ19_03820 ENOG4108Z66 YbaK ebsC protein CEQ19_03825 ENOG4105CUT histidyl-tRNA synthetase CEQ19_03840 ENOG4105KVH Transcriptional regulator CEQ19_03845 ENOG4108RCM Nitroreductase CEQ19_03870 ENOG4108PSK reductase CEQ19_03880 ENOG4105CJ1 ABC, transporter CEQ19_03940 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_03945 ENOG4105DKQ ROK family CEQ19_03950 ENOG4106UW1 Major Facilitator superfamily CEQ19_03955 ENOG4108UW5 maltose o-acetyltransferase CEQ19_03970 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) CEQ19_03980 ENOG4105C31 Tryptophanyl-tRNA synthetase CEQ19_03985 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) CEQ19_04010 ENOG4105DMQ Methyltransferase CEQ19_04020 ENOG4105EV4 Multidrug resistance protein mdtH CEQ19_04050 ENOG4105C37 (CBS) domain CEQ19_04065 ENOG4105DDN Pentapeptide repeat-containing protein CEQ19_04070 ENOG4105XDF Protein of unknown function (DUF1272) CEQ19_04075 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) CEQ19_04080 ENOG4105CMG Carbohydrate kinase CEQ19_04085 ENOG4105C6Z Gluconate CEQ19_04090 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEQ19_04105 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CEQ19_04110 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CEQ19_04115 ENOG4105CIS alcohol dehydrogenase CEQ19_04120 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone CEQ19_04140 ENOG4105EWI Short-chain dehydrogenase reductase Sdr CEQ19_04145 ENOG4105D4Y metalloprotease CEQ19_04165 ENOG4105CV8 reductase CEQ19_04170 ENOG4105F27 Major Facilitator CEQ19_04190 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) CEQ19_04195 ENOG4105C44 Serine transporter CEQ19_04230 ENOG4105KVH Transcriptional regulator CEQ19_04235 ENOG4108TZY GntR Family Transcriptional Regulator CEQ19_04245 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CEQ19_04250 ENOG4105KVH Transcriptional regulator CEQ19_04255 ENOG4105KVH Transcriptional regulator CEQ19_04290 ENOG4105JAB phenazine biosynthesis protein, phzf family CEQ19_04300 ENOG4105CHR reductase CEQ19_04320 ENOG4105KVH Transcriptional regulator CEQ19_04395 ENOG4105KAF membrAne CEQ19_04425 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) CEQ19_04445 ENOG4107YXZ hydrolase, family 25 CEQ19_04470 ENOG4105ED2 Beta-lactamase CEQ19_04480 ENOG4105H3G oxidoreductase CEQ19_04560 ENOG4108TN2 lmbE family CEQ19_04570 ENOG4107R3E Citrate transporter CEQ19_04600 ENOG4105EHG Permease protein CEQ19_04605 ENOG4105DQ5 transport system permease protein CEQ19_04610 ENOG4105NX3 Membrane CEQ19_04615 ENOG4107ZY0 Phenazine biosynthesis-like protein CEQ19_04635 ENOG4107CUJ Protein of unknown function (DUF2690) CEQ19_04645 ENOG4107V2S Transcriptional regulator CEQ19_04665 ENOG4105C98 muts2 protein CEQ19_04675 ENOG4105E5K Alpha-amylase CEQ19_04685 ENOG4105DPN Oligoendopeptidase f CEQ19_04690 ENOG4108A04 Beta-lactamase CEQ19_04720 ENOG4107VXM glycerophosphoryl diester phosphodiesterase CEQ19_04745 ENOG41082BM Transcriptional regulator, arsr family CEQ19_04750 ENOG4105CIS alcohol dehydrogenase CEQ19_04775 ENOG4105RHY Pfam:UPF0157 CEQ19_04785 ENOG4105C09 Bile acid CEQ19_04790 ENOG4105CQB FAD linked oxidase domain protein CEQ19_04820 ENOG4108UT6 Transferase hexapeptide repeat containing protein CEQ19_04830 ENOG4105K64 Glycosyl transferase, family 2 CEQ19_04835 ENOG4105E39 Enoyl-CoA hydratase CEQ19_04845 ENOG4105KT7 mgtC SapB transporter CEQ19_04860 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_04865 ENOG41073R8 VanW family CEQ19_04875 ENOG4108R1P CEQ19_04895 ENOG4105VEQ Cold shock protein CEQ19_04915 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) CEQ19_04935 ENOG410904N short-chain dehydrogenase reductase CEQ19_04945 ENOG4106IQC argininosuccinate lyase CEQ19_04960 ENOG4108IA2 Sodium pantothenate symporter CEQ19_04970 ENOG4105C26 Dehydrogenase CEQ19_04975 ENOG4105CHR reductase CEQ19_04985 ENOG4105EWU Squalene--hopene cyclase CEQ19_04995 ENOG4105FR1 rard protein CEQ19_05000 ENOG410696E Membrane CEQ19_05015 ENOG4105D1F ATP-binding protein CEQ19_05025 ENOG4108ZAF Molybdopterin CEQ19_05030 ENOG4105CVM Molybdenum cofactor synthesis domain protein CEQ19_05035 ENOG4105D06 uba thif-type nad fad binding protein CEQ19_05040 ENOG4105TMB Formate nitrite transporter CEQ19_05055 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) CEQ19_05060 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) CEQ19_05070 ENOG4108JB9 formate dehydrogenase CEQ19_05080 ENOG4105E1K spore germination protein CEQ19_05140 ENOG4107QJT sodium dicarboxylate symporter CEQ19_05145 ENOG4108KGH TRANSCRIPTIONal CEQ19_05155 ENOG4105EMN RNA polymerase sigma factor CEQ19_05180 ENOG4105CIG ABC transporter CEQ19_05190 ENOG4105D9R oxidoreductase CEQ19_05200 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ19_05210 ENOG4105K4P CoA-binding domain protein CEQ19_05215 ENOG4105C0H protease CEQ19_05220 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_05230 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CEQ19_05235 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) CEQ19_05240 ENOG4105W8X HesB YadR YfhF-family protein CEQ19_05270 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) CEQ19_05280 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CEQ19_05290 ENOG4108JJA ABC, transporter CEQ19_05295 ENOG4108I0Z Aconitate hydratase CEQ19_05335 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CEQ19_05355 ENOG4107F3J Amp-dependent synthetase and ligase CEQ19_05360 ENOG4107ZYJ bioY protein CEQ19_05365 ENOG4105CEY Amp-dependent synthetase and ligase CEQ19_05420 ENOG4107AYK membrAne CEQ19_05435 ENOG4105BZU Histidine kinase CEQ19_05440 ENOG4105FBA Phospholipase Carboxylesterase CEQ19_05445 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase CEQ19_05450 ENOG4105CK7 Sodium proline symporter CEQ19_05455 ENOG4105CBC glutamate synthase CEQ19_05460 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEQ19_05465 ENOG4108VJ1 Transcriptional regulator (CarD family CEQ19_05470 ENOG4108903 Formimidoylglutamase CEQ19_05495 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) CEQ19_05560 ENOG4107QIV Cytochrome c biogenesis protein CEQ19_05575 ENOG4107RSM transcriptional regulator CEQ19_05580 ENOG4105VAW lrga family CEQ19_05585 ENOG41067MG lrgb family CEQ19_05610 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase CEQ19_05625 ENOG4105BZ1 (ABC) transporter CEQ19_05630 ENOG4105BZ1 (ABC) transporter CEQ19_05655 ENOG4105D7V transposase CEQ19_05675 ENOG4105D5T phosphonate abc transporter CEQ19_05695 ENOG4108SVB resolvase CEQ19_05715 ENOG4105K7K Transcriptional regulator CEQ19_05760 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase CEQ19_05765 ENOG4105XSJ toxin secretion phage lysis holin CEQ19_05970 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) CEQ19_06085 ENOG4105C5F glutamine synthetase CEQ19_06090 ENOG4105KV4 Transcriptional regulator CEQ19_06095 ENOG4105CXI aluminum resistance protein CEQ19_06105 ENOG4105EN6 Membrane CEQ19_06115 ENOG4106F1P AAA ATPase, central domain protein CEQ19_06145 ENOG41069ER domain protein CEQ19_06155 ENOG4105DM4 PTS System CEQ19_06160 ENOG4105DE4 1-phosphofructokinase CEQ19_06165 ENOG4105E98 transcriptional regulator DeoR family CEQ19_06175 ENOG4108SJC Membrane CEQ19_06190 ENOG4105C85 amino acid CEQ19_06215 ENOG4105TMB Formate nitrite transporter CEQ19_06220 ENOG4105K70 DNA-binding protein CEQ19_06230 ENOG4105C59 p-type ATPase CEQ19_06235 ENOG410681U heavy metal transport detoxification protein CEQ19_06240 ENOG4105VPX protein, conserved in bacteria CEQ19_06250 ENOG4105NIV Esterase CEQ19_06255 ENOG4105E0A ABC, transporter CEQ19_06275 ENOG4105CGK Exodeoxyribonuclease III CEQ19_06285 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEQ19_06290 ENOG4105D03 DNA-3-methyladenine glycosylase II CEQ19_06320 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_06325 ENOG4105BZU Histidine kinase CEQ19_06345 ENOG41067MG lrgb family CEQ19_06360 ENOG4107TTQ Alpha beta hydrolase fold CEQ19_06365 ENOG4107YEI lmbE family CEQ19_06390 ENOG4105F0V Cell wall hydrolase CEQ19_06395 ENOG4107R6R udp-galactopyranose mutase CEQ19_06400 ENOG4105E0M Sulfatase CEQ19_06405 ENOG410890F Dynamin family CEQ19_06415 ENOG4107QHE Choloylglycine hydrolase CEQ19_06440 ENOG4105DA5 (ABC) transporter CEQ19_06465 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) CEQ19_06470 ENOG4105DQU oxidoreductase, subunit beta CEQ19_06475 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein CEQ19_06480 ENOG4108IGT Dipeptidase CEQ19_06485 ENOG4105MCT stage V sporulation protein S CEQ19_06490 ENOG4105D48 metallophosphoesterase CEQ19_06515 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase CEQ19_06530 ENOG4105XZV Protein of unknown function (DUF3243) CEQ19_06535 ENOG4108RKS Short-chain dehydrogenase reductase Sdr CEQ19_06565 ENOG4108JQ9 ABC transporter CEQ19_06570 ENOG4105DIH basic membrane CEQ19_06575 ENOG4105FDP GntR family transcriptional regulator CEQ19_06580 ENOG4107QZI cell division protein FtsK CEQ19_06590 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit CEQ19_06605 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CEQ19_06615 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEQ19_06620 ENOG4108S0H Dipicolinic acid synthetase, b subunit CEQ19_06625 ENOG4105E35 Dipicolinate synthase subunit A CEQ19_06640 ENOG4105C1V Peptidase, M16 CEQ19_06660 ENOG4105DTN riboflavin biosynthesis protein ribF CEQ19_06665 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) CEQ19_06675 ENOG4105W7A Protein of unknown function (DUF503) CEQ19_06685 ENOG4105VHM ribosomal protein CEQ19_06690 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination CEQ19_06695 ENOG4105CHV Transcription elongation factor NusA CEQ19_06705 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) CEQ19_06720 ENOG4105DZP Membrane-associated zinc metalloprotease CEQ19_06725 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) CEQ19_06730 ENOG4105KNE Phosphatidate cytidylyltransferase CEQ19_06735 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CEQ19_06775 ENOG4108HE4 integrase family CEQ19_06785 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CEQ19_06795 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CEQ19_06810 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) CEQ19_06835 ENOG4105VB6 UPF0109 protein CEQ19_06855 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CEQ19_06860 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) CEQ19_06875 ENOG4105CHR reductase CEQ19_06880 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CEQ19_06895 ENOG4105CB5 ATP-dependent DNA helicase recG CEQ19_06900 ENOG4105DP4 dak2 domain fusion protein ylov CEQ19_06905 ENOG4108ZAA Alkaline-shock protein CEQ19_06920 ENOG4105FJ0 thiamine CEQ19_06925 ENOG4105DJV ribulose-phosphate 3-epimerase CEQ19_06930 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) CEQ19_06935 ENOG4105D9P serine threonine protein kinase CEQ19_06940 ENOG4108ZF3 Phosphatase CEQ19_06950 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B CEQ19_06960 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CEQ19_06965 ENOG4105C25 Primosomal protein n' CEQ19_06970 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CEQ19_06990 ENOG4105DSJ YicC domain protein CEQ19_07000 ENOG4105F23 Fibronectin-binding protein CEQ19_07005 ENOG4105DC7 peptidase M24 CEQ19_07065 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CEQ19_07090 ENOG4105C34 Pseudouridine synthase CEQ19_07105 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) CEQ19_07115 ENOG4105DBK s4 domain protein CEQ19_07120 ENOG41067XK integral membrane protein CEQ19_07130 ENOG4105DFA alanine racemase domain protein CEQ19_07135 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CEQ19_07140 ENOG4105WR5 sporulation protein, YlmC YmxH family CEQ19_07150 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_07160 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CEQ19_07165 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CEQ19_07170 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) CEQ19_07175 ENOG4105D4A Cell wall formation (By similarity) CEQ19_07180 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) CEQ19_07185 ENOG4105CNI cell division protein FtsW CEQ19_07200 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CEQ19_07205 ENOG4105CJN penicillin-binding protein CEQ19_07210 ENOG4105CJN penicillin-binding protein CEQ19_07215 ENOG41068DC Essential cell division protein (By similarity) CEQ19_07250 ENOG4105KNH Nucleic acid-binding protein CEQ19_07300 ENOG4105XSJ toxin secretion phage lysis holin CEQ19_07380 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) CEQ19_07390 ENOG4105CAR Terminase, large subunit CEQ19_07495 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) CEQ19_07510 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_07565 ENOG4108IMY Transcriptional regulator CEQ19_07600 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) CEQ19_07610 ENOG41063PX domain protein CEQ19_07615 ENOG4105D78 K07001 NTE family protein CEQ19_07620 ENOG4105H20 Sporulation integral membrane protein YlbJ CEQ19_07630 ENOG4106H78 methyltransferase CEQ19_07650 ENOG4107TB6 phosphoglycerate mutase CEQ19_07665 ENOG4106UY4 Inherit from COG: Scp-like extracellular CEQ19_07715 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) CEQ19_07725 ENOG4105CNI cell division protein FtsW CEQ19_07740 ENOG4108IAB Phoh family CEQ19_07760 ENOG4105QA2 CEQ19_07765 ENOG4105CI3 gtp-binding protein typa CEQ19_07775 ENOG4105ECY inositol monophosphatase CEQ19_07795 ENOG4105CXN decarboxylase CEQ19_07840 ENOG4105C7S Dehydrogenase CEQ19_07845 ENOG4105CPP Dehydrogenase, E1 component CEQ19_07860 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CEQ19_07865 ENOG4108X4Q Hydrolase CEQ19_07880 ENOG4105CN5 Metallo-Beta-Lactamase CEQ19_07885 ENOG4107ZYR domain protein CEQ19_07920 ENOG4108XRC Protein of unknown function (DUF458) CEQ19_07930 ENOG4107IN1 Protein of unknown function (DUF1797) CEQ19_07945 ENOG4105EPM Diguanylate phosphodiesterase CEQ19_07950 ENOG4105K6S Short-chain dehydrogenase reductase Sdr CEQ19_07970 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CEQ19_07980 ENOG4105UIN CEQ19_08045 ENOG4108HGU Histidine kinase CEQ19_08055 ENOG4105CHM Aminotransferase CEQ19_08060 ENOG4105FKQ transcriptional regulator CEQ19_08065 ENOG4105EG2 ABC transporter, permease CEQ19_08075 ENOG4107FKK extracellular solute-binding protein family 1 CEQ19_08085 ENOG4105CG3 alpha amylase, catalytic region CEQ19_08130 ENOG4105CHU acetyl-coa acetyltransferase CEQ19_08170 ENOG4105K7K Transcriptional regulator CEQ19_08175 ENOG4105DTD Dehydrogenase CEQ19_08185 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) CEQ19_08195 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CEQ19_08220 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) CEQ19_08245 ENOG4106TD9 Diguanylate cyclase CEQ19_08265 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CEQ19_08280 ENOG4105CID antiterminator CEQ19_08290 ENOG4105FDP GntR family transcriptional regulator CEQ19_08300 ENOG4105CE4 GlcNAc 6-P deacetylase CEQ19_08345 ENOG4107ZE5 PPIases accelerate the folding of proteins CEQ19_08350 ENOG4105PTM secreted protein CEQ19_08355 ENOG4105J7I hydrolase CEQ19_08365 ENOG4105G6R Stage v sporulation protein ae CEQ19_08375 ENOG4105CZ3 stage V sporulation protein ad CEQ19_08380 ENOG41090VF Stage v sporulation protein ac CEQ19_08400 ENOG4105C8J )-transporter CEQ19_08405 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_08415 ENOG41082AN stage II sporulation protein CEQ19_08420 ENOG4105DZ1 carboxypeptidase CEQ19_08430 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family CEQ19_08435 ENOG4105DVE abc transporter atp-binding protein CEQ19_08470 ENOG4105D7N magnesium and cobalt transport protein CorA CEQ19_08495 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ19_08505 ENOG4105I3K Ferric uptake regulator, Fur family CEQ19_08510 ENOG4105MZ9 stage II sporulation protein m CEQ19_08530 ENOG4105CPC Aldo Keto reductase CEQ19_08540 ENOG4105RHY Pfam:UPF0157 CEQ19_08560 ENOG4107SKW Inherit from COG: Alpha beta hydrolase CEQ19_08570 ENOG4105ETE Transcriptional regulator (LacI family CEQ19_08575 ENOG4108YM7 Gcn5-related n-acetyltransferase CEQ19_08595 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CEQ19_08600 ENOG4108R6K riboflavin synthase, subunit alpha CEQ19_08620 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) CEQ19_08625 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CEQ19_08630 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CEQ19_08635 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CEQ19_08645 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CEQ19_08660 ENOG4105DFD Na H antiporter CEQ19_08665 ENOG4105CGH 5'-nucleotidase CEQ19_08705 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) CEQ19_08720 ENOG4108IXY short-chain dehydrogenase reductase CEQ19_08730 ENOG4105II7 pyrroline-5-carboxylate reductase CEQ19_08735 ENOG4105EJQ L-serine dehydratase CEQ19_08765 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CEQ19_08775 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CEQ19_08780 ENOG4105D9U N-acetyltransferase CEQ19_08795 ENOG4108VZI ErfK ybiS ycfS ynhG family protein CEQ19_08800 ENOG4108QEG Membrane CEQ19_08805 ENOG4105CDA abc transporter atp-binding protein CEQ19_08810 ENOG4105E5Q amino acid AbC transporter CEQ19_08815 ENOG4108HW3 (ABC) transporter CEQ19_08830 ENOG4105G7B Protein of unknown function (DUF2992) CEQ19_08835 ENOG4105E09 nadh pyrophosphatase CEQ19_08850 ENOG4105C7S Dehydrogenase CEQ19_08855 ENOG4105CPP Dehydrogenase, E1 component CEQ19_08875 ENOG4107RDP Dehydrogenase CEQ19_08890 ENOG4108JUB Transcriptional regulator CEQ19_08900 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CEQ19_08915 ENOG4107QQR Sporulation CEQ19_08925 ENOG4105S1Z Stage IV sporulation protein B CEQ19_08930 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CEQ19_08940 ENOG4105DX0 Hemolysin A CEQ19_08950 ENOG4105CTB Polyprenyl synthetase CEQ19_08975 ENOG4108ZSR alkaline shock protein CEQ19_08980 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CEQ19_09005 ENOG410644B Stage III sporulation protein af CEQ19_09015 ENOG4105KQ4 Stage iii sporulation protein ad CEQ19_09020 ENOG4108CQH stage III sporulation protein AC CEQ19_09025 ENOG4105KR5 Stage iii sporulation protein CEQ19_09030 ENOG4105CD2 stage iii sporulation protein aa CEQ19_09055 ENOG4105DC7 peptidase M24 CEQ19_09070 ENOG4105CBJ Metal-dependent enzyme CEQ19_09080 ENOG4107YBY Hydrolase CEQ19_09100 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) CEQ19_09105 ENOG4105WZW rhodanese family CEQ19_09125 ENOG41080TC multidrug resistance protein CEQ19_09165 ENOG4105CJ1 ABC, transporter CEQ19_09170 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family CEQ19_09205 ENOG4105C0D helicase CEQ19_09330 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) CEQ19_09335 ENOG4105C3R Methionine synthase CEQ19_09345 ENOG4105C28 cystathionine CEQ19_09350 ENOG4105C28 cystathionine CEQ19_09370 ENOG4105C5X domain protein CEQ19_09380 ENOG4105DKQ ROK family CEQ19_09390 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CEQ19_09405 ENOG4108UTW Plays a role in the regulation of phosphate uptake CEQ19_09410 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) CEQ19_09415 ENOG4105E2Z phosphate ABC transporter (Permease CEQ19_09420 ENOG4105C8U phosphate abc transporter CEQ19_09425 ENOG4105PWN phosphate abc transporter CEQ19_09430 ENOG4107RF6 penicillin-binding protein CEQ19_09440 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEQ19_09465 ENOG4105N80 Ferric uptake regulator, Fur family CEQ19_09475 ENOG4105FDK ABC transporter CEQ19_09480 ENOG4108JYZ YitT family CEQ19_09485 ENOG41069ZM Protein of unknown function (DUF2624) CEQ19_09510 ENOG4105EGD dinuclear metal center protein, YbgI family CEQ19_09525 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_09530 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CEQ19_09570 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) CEQ19_09575 ENOG4105KG3 cytidine deaminase CEQ19_09580 ENOG4107YR5 Diacylglycerol kinase CEQ19_09590 ENOG4105CTJ Metal Dependent Phosphohydrolase CEQ19_09595 ENOG4105C9A Phoh family CEQ19_09610 ENOG41068P3 sporulation protein YqfC CEQ19_09615 ENOG4105KTH gatB Yqey CEQ19_09630 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) CEQ19_09635 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CEQ19_09655 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ CEQ19_09665 ENOG4105CSA Coproporphyrinogen iii oxidase CEQ19_09670 ENOG4105KVH Transcriptional regulator CEQ19_09695 ENOG4105TQK DNA polymerase iii, delta' subunit CEQ19_09705 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 CEQ19_09710 ENOG4108UK2 deaminase CEQ19_09715 ENOG4105KQC Competence protein CEQ19_09725 ENOG4105DXX methyltransferase CEQ19_09735 ENOG4108WF2 Metal Dependent Phosphohydrolase CEQ19_09745 ENOG410812S Rna-binding protein CEQ19_09755 ENOG4105CQW ribosome biogenesis GTPase YqeH CEQ19_09760 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase CEQ19_09775 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_09800 ENOG4108TVJ Nitroreductase CEQ19_09815 ENOG4105G6Z alkaline phosphatase CEQ19_09825 ENOG4108MUZ hydrolase CEQ19_09860 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin CEQ19_09865 ENOG4105MIR Phenylalanine 4-monooxygenase CEQ19_09915 ENOG4105S6R Iron-hydroxamate transporter permease subunit CEQ19_09920 ENOG4108V5C ABC transporter CEQ19_09935 ENOG4108EKI Dehydrogenase CEQ19_09940 ENOG4105C28 cystathionine CEQ19_09970 ENOG4107XRG penicillin-binding protein CEQ19_09985 ENOG4105CFP Peptidase U32 CEQ19_09990 ENOG4105XYU peptidase (U32 family) CEQ19_09995 ENOG4108VQJ O-methyltransferase CEQ19_10000 ENOG4105HHA aminodeoxychorismate lyase CEQ19_10020 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CEQ19_10030 ENOG4105C02 permease CEQ19_10045 ENOG41060CR CEQ19_10050 ENOG4105C7H Helicase, RecD TraA family CEQ19_10060 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) CEQ19_10065 ENOG4105C3J Cysteine desulfurase CEQ19_10075 ENOG4105D1H recombination factor protein RarA CEQ19_10080 ENOG4108VCI transcription factor, rsfa family CEQ19_10085 ENOG4105CUZ uba thif-type nad fad binding protein CEQ19_10095 ENOG4105CUT histidyl-tRNA synthetase CEQ19_10115 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CEQ19_10125 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CEQ19_10130 ENOG41076HS cation diffusion facilitator family transporter CEQ19_10135 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CEQ19_10145 ENOG4105CKP Polysaccharide Biosynthesis Protein CEQ19_10150 ENOG4108QG2 Membrane CEQ19_10160 ENOG4105VIE preprotein translocase, subunit YajC CEQ19_10175 ENOG41061AI Protein of unknown function (DUF2905) CEQ19_10190 ENOG4108HUF Transporter CEQ19_10200 ENOG4108IPJ Membrane CEQ19_10205 ENOG4108IPJ Membrane CEQ19_10210 ENOG41082BM Transcriptional regulator, arsr family CEQ19_10235 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CEQ19_10240 ENOG4108IYU L-aspartate oxidase CEQ19_10255 ENOG4108RPX mosc domain containing protein CEQ19_10260 ENOG4105CQC Prephenate dehydratase CEQ19_10290 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control CEQ19_10305 ENOG4105X36 (ribosomal) protein CEQ19_10315 ENOG4105C03 ribonuclease CEQ19_10330 ENOG4107QMS site-determining protein CEQ19_10345 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CEQ19_10350 ENOG4105DFF Rod shape-determining protein mreb CEQ19_10375 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CEQ19_10380 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CEQ19_10390 ENOG41068KH stage VI sporulation protein D CEQ19_10400 ENOG4105D52 delta-aminolevulinic acid dehydratase CEQ19_10425 ENOG4105K56 Transcriptional regulator CEQ19_10445 ENOG4108IUQ atp-dependent protease CEQ19_10475 ENOG4108QCI YvbH-like oligomerisation region CEQ19_10500 ENOG4105M59 Phosphodiesterase, mj0936 family CEQ19_10515 ENOG4108XJQ germination protein CEQ19_10525 ENOG4108PCX Major Facilitator CEQ19_10535 ENOG4105KBX Transcriptional regulator, TetR family CEQ19_10550 ENOG4105PFC Transcriptional regulator CEQ19_10565 ENOG4105DZC cytosine deaminase CEQ19_10570 ENOG4105DZC cytosine deaminase CEQ19_10575 ENOG4105DEF Extracellular solute-binding protein, family 5 CEQ19_10580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ19_10595 ENOG4108JQ7 (ABC) transporter CEQ19_10605 ENOG4105DY9 regulatoR CEQ19_10620 ENOG41067S9 phage shock protein C, PspC CEQ19_10625 ENOG4108JCI Transcriptional regulator CEQ19_10635 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CEQ19_10640 ENOG4108Z40 Transcriptional regulator CEQ19_10645 ENOG4105RHA ABC transporter, permease CEQ19_10650 ENOG4108IUX (ABC) transporter CEQ19_10655 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family CEQ19_10665 ENOG4105E14 MotA TolQ exbB proton channel CEQ19_10670 ENOG4108VXD carboxy-peptidase CEQ19_10680 ENOG4105E33 succinate dehydrogenase CEQ19_10690 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit CEQ19_10705 ENOG4105K63 Thioredoxin CEQ19_10710 ENOG4105C10 Electron transfer flavoprotein CEQ19_10715 ENOG4105BZJ Electron transfer flavoprotein CEQ19_10720 ENOG41060WC Enoyl-CoA hydratase CEQ19_10725 ENOG4107Z3H Transcriptional regulator, TetR family CEQ19_10730 ENOG4105CEY Amp-dependent synthetase and ligase CEQ19_10745 ENOG4105J76 Periplasmic binding protein CEQ19_10750 ENOG4105S6R Iron-hydroxamate transporter permease subunit CEQ19_10795 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_10810 ENOG4105DR4 Methyltransferase CEQ19_10825 ENOG4105KFN sortase, SrtB family CEQ19_10830 ENOG4105E0A ABC, transporter CEQ19_10845 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) CEQ19_10855 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) CEQ19_10865 ENOG4105FE9 pseudouridine synthase CEQ19_10880 ENOG4105DCG PHP domain protein CEQ19_10915 ENOG4105C5S asparaginyl-tRNA synthetase CEQ19_10920 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CEQ19_10930 ENOG4108RWN rrna methyltransferase CEQ19_10965 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ19_10970 ENOG4105CW7 secretion protein, HlyD family CEQ19_10975 ENOG4108JGH Tetr family transcriptional regulator CEQ19_10980 ENOG4105CN9 Peptidase m42 family protein CEQ19_11000 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) CEQ19_11005 ENOG4105C22 threonyL-tRNA synthetase CEQ19_11010 ENOG4108TDW sporulation protein YtxC CEQ19_11030 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) CEQ19_11040 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CEQ19_11045 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CEQ19_11055 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) CEQ19_11060 ENOG4105C2M dna polymerase I CEQ19_11065 ENOG4105BZU Histidine kinase CEQ19_11070 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_11095 ENOG4108HMX isocitrate dehydrogenase (NADP) CEQ19_11100 ENOG4105BZN citrate synthase CEQ19_11115 ENOG4108REF Sporulation integral membrane protein ytvi CEQ19_11120 ENOG4105FS0 cytoplasmic membrane protein CEQ19_11145 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family CEQ19_11150 ENOG4105C6K Malic enzyme CEQ19_11155 ENOG4105C0B DNA polymerase III (alpha subunit) CEQ19_11160 ENOG4105VV2 CEQ19_11170 ENOG4105SFS phosphoesterase RecJ domain protein CEQ19_11210 ENOG4105DC7 peptidase M24 CEQ19_11250 ENOG4105Z7P Acetyltransferase (GNAT) family CEQ19_11255 ENOG41082W1 Cupin 2, conserved barrel domain protein CEQ19_11265 ENOG4105VZ8 Transcriptional regulator CEQ19_11285 ENOG4107YZX Universal stress protein CEQ19_11335 ENOG4108JYZ YitT family CEQ19_11355 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) CEQ19_11365 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CEQ19_11370 ENOG4105KBJ sporulation protein ytfj CEQ19_11385 ENOG4105EFZ amidohydrolase CEQ19_11395 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CEQ19_11420 ENOG4106KR7 LysR family Transcriptional regulator CEQ19_11440 ENOG4105C28 cystathionine CEQ19_11465 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) CEQ19_11475 ENOG4105EMN RNA polymerase sigma factor CEQ19_11490 ENOG4105F1V Acetoin utilization protein CEQ19_11495 ENOG4105W87 Cbs domain CEQ19_11500 ENOG4105DGU Histone deacetylase CEQ19_11510 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_11520 ENOG4107SNB ankyrin repeat protein YahD CEQ19_11525 ENOG4105EP9 oxidoreductase CEQ19_11555 ENOG4105ETE Transcriptional regulator (LacI family CEQ19_11580 ENOG4105C88 aminopeptidase CEQ19_11625 ENOG4108VDD TRNA binding domain protein CEQ19_11655 ENOG4105C8F Beta-lactamase domain protein CEQ19_11670 ENOG4108V15 phosphotransferase enzyme family CEQ19_11675 ENOG4108IUM Glycogen debranching enzyme CEQ19_11695 ENOG4105YW5 deoR family transcriptional regulator CEQ19_11710 ENOG4105CBX hi0933 family CEQ19_11755 ENOG4108VJ1 Transcriptional regulator (CarD family CEQ19_11760 ENOG4107EXU Short-chain dehydrogenase reductase Sdr CEQ19_11765 ENOG4105CSC Glucose uptake protein CEQ19_11780 ENOG4108ZAF Molybdopterin CEQ19_11785 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein CEQ19_11790 ENOG4105CVM Molybdenum cofactor synthesis domain protein CEQ19_11800 ENOG4105D06 uba thif-type nad fad binding protein CEQ19_11825 ENOG41085GJ domain protein CEQ19_11835 ENOG4105DWV Homoserine O-trans-acetylase CEQ19_11845 ENOG4108B31 Spore germination protein CEQ19_11880 ENOG410605W Major Facilitator CEQ19_11885 ENOG4107S91 Sodium hydrogen exchanger CEQ19_11890 ENOG4105NCW Trka-c domain protein CEQ19_11905 ENOG4105C19 ABC transporter CEQ19_11925 ENOG4105N5T Radical SAM Protein CEQ19_11935 ENOG4105DA5 (ABC) transporter CEQ19_11965 ENOG4105E8V Alpha Beta Hydrolase Fold protein CEQ19_11970 ENOG4108Z0R Transferase CEQ19_11975 ENOG4105YVM Phosphoesterase, PA-phosphatase related CEQ19_11980 ENOG4105BZF Glycosyl transferase (Group 1 CEQ19_11990 ENOG4108RIR Molybdenum cofactor biosynthesis protein CEQ19_12050 ENOG4105EGD dinuclear metal center protein, YbgI family CEQ19_12055 ENOG4105BZU Histidine kinase CEQ19_12060 ENOG4105BZU Histidine kinase CEQ19_12065 ENOG4107S9D Alpha beta hydrolase CEQ19_12070 ENOG4107T7U Sulfatase CEQ19_12090 ENOG4105D2X ABC transporter substrate-binding protein CEQ19_12100 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component CEQ19_12165 ENOG4108V2W Carbonate dehydratase CEQ19_12170 ENOG4105C4M (Ubiquinol oxidase) subunit I CEQ19_12175 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CEQ19_12225 ENOG41087YS Phage shock protein A CEQ19_12260 ENOG4105BZU Histidine kinase CEQ19_12265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_12290 ENOG4108UGV hypoxanthine phosphoribosyltransferase CEQ19_12295 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) CEQ19_12335 ENOG4107ZTW SNARE associated Golgi CEQ19_12350 ENOG4105C19 ABC transporter CEQ19_12355 ENOG41086D8 Transcriptional regulator CEQ19_12395 ENOG4105C6Z Gluconate CEQ19_12400 ENOG4105FDP GntR family transcriptional regulator CEQ19_12420 ENOG41069H0 dihydroorotase EC 3.5.2.3 CEQ19_12450 ENOG4105DTQ mandelate racemase muconate lactonizing CEQ19_12465 ENOG4108IPT Naphthoate synthase CEQ19_12470 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) CEQ19_12475 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) CEQ19_12480 ENOG4105E4F Isochorismate synthase CEQ19_12485 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CEQ19_12495 ENOG4105VEQ Cold shock protein CEQ19_12520 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) CEQ19_12530 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) CEQ19_12555 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CEQ19_12655 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation CEQ19_12700 ENOG4105KT7 mgtC SapB transporter CEQ19_12705 ENOG4107PBV potassium channel CEQ19_12715 ENOG4107QYV phosphohexose isomerase CEQ19_12725 ENOG4105WG9 Conserved Protein CEQ19_12735 ENOG4105CHM Aminotransferase CEQ19_12740 ENOG4108ZB6 transcriptional regulator AsnC family CEQ19_12745 ENOG4105C5I Dehydrogenase CEQ19_12750 ENOG4108MUZ hydrolase CEQ19_12760 ENOG4105C87 Aminotransferase class I and II CEQ19_12775 ENOG4105Y38 Kinase-associated protein B CEQ19_12785 ENOG4107R3E Citrate transporter CEQ19_12805 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) CEQ19_12810 ENOG4105KA0 thioesterase Superfamily protein CEQ19_12830 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEQ19_12850 ENOG41069ER domain protein CEQ19_12865 ENOG4105CEP NADH dehydrogenase CEQ19_12895 ENOG4105EWC Purine nucleoside phosphorylase CEQ19_12915 ENOG4108YX9 iron--sulfur cluster insertion protein erpA CEQ19_12940 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_12945 ENOG4105C4B ABC transporter, permease CEQ19_12950 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CEQ19_12995 ENOG41083MR nifu domain-containing protein CEQ19_13010 ENOG4108W5N phosphatidylglycerophosphatase a CEQ19_13020 ENOG4105DYS nad(p)h dehydrogenase (quinone) CEQ19_13025 ENOG4105D4U had-superfamily hydrolase, subfamily iia CEQ19_13040 ENOG4105CBT Fructose-1,6-bisphosphatase CEQ19_13060 ENOG4105MMD transcriptional regulator CEQ19_13065 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CEQ19_13070 ENOG4107TXC Transcriptional regulator CEQ19_13075 ENOG41090T1 Membrane CEQ19_13100 ENOG4105FAA peptidase M23 CEQ19_13110 ENOG4105KZD Domain of unknown function (DUF1805) CEQ19_13115 ENOG4107R8B 5'-nucleotidase CEQ19_13135 ENOG4105DIW FeS assembly protein SUFB CEQ19_13140 ENOG4108UNV SUF system FeS assembly protein, NifU family CEQ19_13145 ENOG4105C9B Cysteine desulfurase CEQ19_13150 ENOG4105JRK feS assembly protein SufD CEQ19_13155 ENOG4105C3K feS assembly ATPase SufC CEQ19_13160 ENOG4105D01 (LipO)protein CEQ19_13165 ENOG4105D01 (LipO)protein CEQ19_13170 ENOG4108UMI ABC transporter, permease CEQ19_13215 ENOG41080E8 Transcriptional regulator, Spx MgsR family CEQ19_13270 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CEQ19_13300 ENOG4108W8B Beta-lactamase domain protein CEQ19_13305 ENOG4105C1G acyl-Coa dehydrogenase CEQ19_13315 ENOG4105CHU acetyl-coa acetyltransferase CEQ19_13335 ENOG4105DZ1 carboxypeptidase CEQ19_13355 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CEQ19_13375 ENOG4108SUT Major Facilitator Superfamily CEQ19_13380 ENOG4107R7I amino acid CEQ19_13390 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CEQ19_13400 ENOG4107AYK membrAne CEQ19_13440 ENOG4107ZTW SNARE associated Golgi CEQ19_13450 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CEQ19_13455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_13460 ENOG4105BZU Histidine kinase CEQ19_13470 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) CEQ19_13485 ENOG4105VG1 fes assembly suf system protein CEQ19_13490 ENOG4105D4Y metalloprotease CEQ19_13510 ENOG4107S91 Sodium hydrogen exchanger CEQ19_13515 ENOG4105NCW Trka-c domain protein CEQ19_13530 ENOG4108RMU ferritin dps family protein CEQ19_13545 ENOG4108URH decarboxylase CEQ19_13570 ENOG4105D9N nucleoside CEQ19_13575 ENOG4105D9N nucleoside CEQ19_13590 ENOG4108RYK Nad-dependent epimerase dehydratase CEQ19_13620 ENOG4105CV8 reductase CEQ19_13625 ENOG4105F27 Major Facilitator CEQ19_13630 ENOG4105KVH Transcriptional regulator CEQ19_13645 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) CEQ19_13650 ENOG4105D4A Cell wall formation (By similarity) CEQ19_13660 ENOG4105C8Q Methyl-accepting chemotaxis CEQ19_13670 ENOG4105WMR Protein CrcB homolog CEQ19_13675 ENOG4105WMR Protein CrcB homolog CEQ19_13690 ENOG4108MK9 spermidine N(1)-acetyltransferase CEQ19_13695 ENOG4108VY7 phosphate-starvation-inducible protein PsiE CEQ19_13715 ENOG4108IPW abc transporter atp-binding protein CEQ19_13720 ENOG4105CM4 permease protein CEQ19_13750 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CEQ19_13760 ENOG4105XZU Preprotein translocase, subunit SecG CEQ19_13765 ENOG41067MG lrgb family CEQ19_13875 ENOG4105EFC phage portal protein HK97 family CEQ19_13900 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ19_13910 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) CEQ19_13915 ENOG4105CP7 Triose-phosphate isomerase CEQ19_13940 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_13960 ENOG41090VF Stage v sporulation protein ac CEQ19_13965 ENOG4105CZ3 stage V sporulation protein ad CEQ19_13980 ENOG4105H67 Protein of unknown function (DUF421) CEQ19_13985 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) CEQ19_13990 ENOG4105KRI phosphocarrier protein (HPr CEQ19_14000 ENOG4105CHW UPF0052 protein CEQ19_14010 ENOG4108Z4K mutator MutT protein CEQ19_14020 ENOG4105C3M thioredoxin reductase CEQ19_14030 ENOG4108S4C acetyltransferase CEQ19_14050 ENOG41086DT Membrane protein of unknown function CEQ19_14060 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CEQ19_14065 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) CEQ19_14070 ENOG4105D7V transposase CEQ19_14085 ENOG4107TXC Transcriptional regulator CEQ19_14115 ENOG4105DUM transcriptional regulator, lysR family CEQ19_14125 ENOG4108WS4 fmn reductase CEQ19_14140 ENOG4105BZ1 (ABC) transporter CEQ19_14155 ENOG4105CN1 protease CEQ19_14160 ENOG4105CRP Part of the ABC transporter FtsEX involved in CEQ19_14165 ENOG4105CAK Cell division ATP-binding protein ftsE CEQ19_14190 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving CEQ19_14195 ENOG4105MS2 ribosomal subunit Interface protein CEQ19_14200 ENOG4105VEQ Cold shock protein CEQ19_14205 ENOG41081UC Inherit from COG: Competence protein CEQ19_14220 ENOG4105KVH Transcriptional regulator CEQ19_14235 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CEQ19_14240 ENOG4108KGH TRANSCRIPTIONal CEQ19_14245 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CEQ19_14250 ENOG4105C6Y Udp-glucose 6-dehydrogenase CEQ19_14255 ENOG4105ESV Glycosyl transferase, family 4 CEQ19_14265 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEQ19_14280 ENOG410901P UPF0249 protein CEQ19_14285 ENOG4105F8D glycoside hydrolase family 4 CEQ19_14290 ENOG4105VCP PTS System CEQ19_14295 ENOG4105CK1 PTS System CEQ19_14305 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) CEQ19_14310 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) CEQ19_14315 ENOG4105VCP PTS System CEQ19_14325 ENOG4105VZJ PTS System CEQ19_14340 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_14345 ENOG4105ECB domain protein CEQ19_14350 ENOG4107RSM transcriptional regulator CEQ19_14395 ENOG4105DAA L-lactate CEQ19_14405 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) CEQ19_14420 ENOG4105E0M Sulfatase CEQ19_14460 ENOG4105C94 Transporter CEQ19_14470 ENOG41069ER domain protein CEQ19_14495 ENOG4105KBK Zinc finger, swim domain protein CEQ19_14500 ENOG4105C0D helicase CEQ19_14530 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_14540 ENOG4107RBB ABC transporter, permease CEQ19_14545 ENOG4105C19 ABC transporter CEQ19_14565 ENOG4105CXY transporter CEQ19_14580 ENOG4105BZU Histidine kinase CEQ19_14585 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_14590 ENOG4105CMR udp-glucose 4-epimerase CEQ19_14605 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CEQ19_14610 ENOG4105EY8 ABC transporter CEQ19_14665 ENOG4105MT0 Sporulation transcriptional regulator spoiiid CEQ19_14680 ENOG4105FRN stage II sporulation protein CEQ19_14715 ENOG4106778 Protein of unknown function (DUF1146) CEQ19_14725 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEQ19_14730 ENOG4105C8S subunit m CEQ19_14735 ENOG4105D65 subunit l CEQ19_14760 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEQ19_14765 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain CEQ19_14775 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain CEQ19_14780 ENOG4105BZU Histidine kinase CEQ19_14835 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) CEQ19_14840 ENOG41062M3 atp synthase CEQ19_14870 ENOG4108YZG isomerase CEQ19_14890 ENOG4108VGI doxx family CEQ19_14895 ENOG4107XC4 flavin reductase domain protein, FMN-binding CEQ19_14910 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) CEQ19_14920 ENOG4108ZXQ stage ii sporulation protein r CEQ19_14925 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CEQ19_14930 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) CEQ19_14945 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) CEQ19_14950 ENOG4105CBT Fructose-1,6-bisphosphatase CEQ19_14960 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) CEQ19_14995 ENOG4105C1G acyl-Coa dehydrogenase CEQ19_15000 ENOG4105C1G acyl-Coa dehydrogenase CEQ19_15005 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase CEQ19_15015 ENOG4105DF6 Fe-S oxidoreductase CEQ19_15030 ENOG4105BZU Histidine kinase CEQ19_15060 ENOG4105BZU Histidine kinase CEQ19_15065 ENOG4105KCT ABC transporter CEQ19_15070 ENOG4108M15 ABC transporter CEQ19_15075 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) CEQ19_15100 ENOG4105IIU Aminopeptidase CEQ19_15120 ENOG4105EMN RNA polymerase sigma factor CEQ19_15130 ENOG410684U Domain of unknown function (DUF1934) CEQ19_15155 ENOG4105CYW agmatinase CEQ19_15165 ENOG4105DXB Major Facilitator superfamily CEQ19_15170 ENOG4107SWG transcriptional regulator MERR family CEQ19_15175 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CEQ19_15180 ENOG4105BZ4 penicillin-binding protein CEQ19_15190 ENOG4108XFG YwhD family CEQ19_15195 ENOG4108Z4T Peptidase M50 CEQ19_15200 ENOG41069HH 4-oxalocrotonate tautomerase CEQ19_15205 ENOG4105DCI Phosphohydrolase CEQ19_15210 ENOG4108MES Periplasmic binding protein CEQ19_15215 ENOG4105E0A ABC, transporter CEQ19_15220 ENOG4105EHG Permease protein CEQ19_15240 ENOG4108VCI transcription factor, rsfa family CEQ19_15255 ENOG4108IJ2 phosphate acetyltransferase CEQ19_15270 ENOG4108VKI Cell wall hydrolase CEQ19_15300 ENOG410667J hydrolase CEQ19_15305 ENOG4105VCH membrane CEQ19_15315 ENOG4108TU7 Inherit from COG: (ABC) transporter CEQ19_15320 ENOG4105CJ1 ABC, transporter CEQ19_15325 ENOG41090WU lipolytic protein G-D-S-L family CEQ19_15340 ENOG4105D6E homoserine dehydrogenase CEQ19_15365 ENOG4108Y4K DNA-binding transcriptional activator CEQ19_15375 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ19_15385 ENOG4105DWF phosphomethylpyrimidine kinase CEQ19_15390 ENOG4105BZU Histidine kinase CEQ19_15395 ENOG4105VCD cytoplasmic protein CEQ19_15400 ENOG4105D22 carbon starvation protein CEQ19_15405 ENOG4105DY9 regulatoR CEQ19_15410 ENOG41079KZ Major Facilitator Superfamily CEQ19_15430 ENOG4105EN6 Membrane CEQ19_15435 ENOG4106YBV Methyl-accepting chemotaxis CEQ19_15445 ENOG4108S4H thioesterase Superfamily protein CEQ19_15455 ENOG4105JEU Glycosyl transferase, family 2 CEQ19_15460 ENOG4105C5H ABC transporter CEQ19_15490 ENOG4105CKK Glycosyl transferase, family 2 CEQ19_15495 ENOG41067SE Tetr family transcriptional regulator CEQ19_15505 ENOG4105E0X reductase CEQ19_15510 ENOG4106F5Q Membrane CEQ19_15525 ENOG4105DY9 regulatoR CEQ19_15530 ENOG4108HRK Histidine kinase CEQ19_15535 ENOG4107RGD Major Facilitator superfamily CEQ19_15555 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEQ19_15565 ENOG4105IW1 AmiS UreI transporter CEQ19_15575 ENOG4105CMR udp-glucose 4-epimerase CEQ19_15580 ENOG4108UT2 hemolysin iii CEQ19_15590 ENOG4105C1J atp-dependent rna helicase CEQ19_15605 ENOG4105DPN Oligoendopeptidase f CEQ19_15625 ENOG4105C0H protease CEQ19_15630 ENOG4105Q2H domain protein CEQ19_15645 ENOG4105BZU Histidine kinase CEQ19_15650 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_15680 ENOG4105CDU Replicative dna helicase CEQ19_15690 ENOG4105BZR domain protein CEQ19_15695 ENOG4108XMW Membrane CEQ19_15705 ENOG4108UUM single-stranded DNA-binding protein CEQ19_15715 ENOG4105C3G gtp-binding protein CEQ19_15720 ENOG4105VDK protein, conserved in bacteria CEQ19_15725 ENOG4105D8X mechanosensitive ion channel CEQ19_15730 ENOG4108ZDA Sporulation protein YyaC CEQ19_15735 ENOG4105FA0 parb-like partition protein CEQ19_15740 ENOG4107QJE Chromosome Partitioning Protein CEQ19_15760 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) CEQ19_15770 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CEQ19_15790 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CEQ19_15795 ENOG410848D S4 domain protein YaaA CEQ19_15810 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ19_15845 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CEQ19_15880 ENOG4105ZMH deoxynucleoside kinase CEQ19_15890 ENOG4105GTG Isochorismatase CEQ19_15900 ENOG4108Z6B deaminase CEQ19_15910 ENOG4105C6E dna polymerase iii CEQ19_15930 ENOG41067KS pro-sigma K processing CEQ19_15965 ENOG4105CXN decarboxylase CEQ19_15975 ENOG4105FA2 dna polymerase iii CEQ19_15980 ENOG4105MA4 psp1 domain protein CEQ19_15990 ENOG41060K3 Methyltransferase CEQ19_16000 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CEQ19_16005 ENOG4105KRN Transcriptional regulator, abrb family CEQ19_16015 ENOG4105F8V Hydrolase, tatD family CEQ19_16020 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) CEQ19_16030 ENOG4105XFA sporulation peptidase YabG CEQ19_16035 ENOG4105W42 Veg protein CEQ19_16050 ENOG4105DFT pur operon repressor CEQ19_16060 ENOG4105KME endoribonuclease L-psp CEQ19_16075 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CEQ19_16080 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) CEQ19_16090 ENOG4108JA2 transcriptioN-repair coupling factor CEQ19_16095 ENOG4108M14 stage v sporulation protein t CEQ19_16105 ENOG4108IY2 MazG family CEQ19_16110 ENOG41082I2 s4 domain protein CEQ19_16115 ENOG4105VYY sporulation protein yabp CEQ19_16130 ENOG41060GV RNA binding s1 domain protein CEQ19_16150 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) CEQ19_16155 ENOG4108UGV hypoxanthine phosphoribosyltransferase CEQ19_16160 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CEQ19_16175 ENOG4105C6T cysteine synthase CEQ19_16180 ENOG4105CRQ synthase (Component I) CEQ19_16185 ENOG4105DDQ anthranilate synthase CEQ19_16190 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 CEQ19_16195 ENOG4105EEI dihydropteroate synthase CEQ19_16200 ENOG4105KRF dihydroneopterin aldolase CEQ19_16205 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CEQ19_16215 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CEQ19_16245 ENOG4108Z0C Uvrb UvrC protein CEQ19_16260 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CEQ19_16270 ENOG4105CTP PilT protein domain protein CEQ19_16290 ENOG4105D7W serine acetyltransferase CEQ19_16305 ENOG4105C2N RNA methyltransferase TrmH family group 3 CEQ19_16310 ENOG4105M0M Tetracycline resistance protein CEQ19_16315 ENOG4105QIV RNA polymerase CEQ19_16330 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CEQ19_16355 ENOG4107Y49 methyltransferase CEQ19_16365 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) CEQ19_16370 ENOG4105XPM ribosomal protein CEQ19_16475 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) CEQ19_16500 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CEQ19_16510 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CEQ19_16520 ENOG41067V7 50S ribosomal protein L36 CEQ19_16550 ENOG4108JJB ABC transporter CEQ19_16555 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) CEQ19_16560 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) CEQ19_16585 ENOG4105D1F ATP-binding protein CEQ19_16600 ENOG4108NMV polysaccharide deacetylase CEQ19_16690 ENOG4105C8B TIGR00159 family CEQ19_16695 ENOG4107U5W ybbr family CEQ19_16710 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CEQ19_16715 ENOG4108VQT Alpha beta hydrolase fold protein CEQ19_16740 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CEQ19_16745 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein CEQ19_16785 ENOG4108UMI ABC transporter, permease CEQ19_16790 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_16795 ENOG4105D01 (LipO)protein CEQ19_16800 ENOG4105EE1 crotonyl-CoA reductase CEQ19_16810 ENOG4105IQ5 FAD linked oxidase domain protein CEQ19_16825 ENOG4105C2C drug resistance transporter, Bcr CflA CEQ19_16840 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ19_16845 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ19_16850 ENOG4105C3U ABC transporter CEQ19_16855 ENOG4108JQ7 (ABC) transporter CEQ19_16885 ENOG4108J59 Extracellular solute-binding protein, family 5 CEQ19_16890 ENOG4108J59 Extracellular solute-binding protein, family 5 CEQ19_16900 ENOG4105II7 pyrroline-5-carboxylate reductase CEQ19_16910 ENOG4107XDY Nicotinamide Mononucleotide Transporter CEQ19_16920 ENOG4105E0C molybdate abc transporter CEQ19_16930 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family CEQ19_16950 ENOG4105EGI Transcriptional regulator CEQ19_16970 ENOG4105F6E Acyl-transferase CEQ19_16990 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) CEQ19_17005 ENOG4108RE7 deoxyribonuclease CEQ19_17010 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) CEQ19_17035 ENOG4105C5H ABC transporter CEQ19_17050 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CEQ19_17060 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ19_17065 ENOG4105C3U ABC transporter CEQ19_17070 ENOG4108JQ7 (ABC) transporter CEQ19_17095 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase CEQ19_17100 ENOG4105ERH Fumarylacetoacetate hydrolase CEQ19_17115 ENOG4108SC4 )-transporter CEQ19_17125 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) CEQ19_17140 ENOG4107ZXI Rhomboid family CEQ19_17150 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein CEQ19_17155 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEQ19_17165 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) CEQ19_17265 ENOG4105K8N protein family UPF0079, ATPase CEQ19_17270 ENOG41072GX Peptidase M22 Glycoprotease CEQ19_17275 ENOG410801F ribosomal-protein-alanine acetyltransferase CEQ19_17280 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) CEQ19_17285 ENOG4105C5H ABC transporter CEQ19_17300 ENOG4108TYN CAAX amino terminal protease family protein CEQ19_17320 ENOG4105C7N Xanthine uracil vitamin C permease CEQ19_17330 ENOG4105BZU Histidine kinase CEQ19_17360 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CEQ19_17410 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) CEQ19_17430 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_17455 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CEQ19_17460 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CEQ19_17465 ENOG4105C83 adenylosuccinate lyase CEQ19_17475 ENOG4105VR9 phosphoribosylformylglycinamidine synthase CEQ19_17500 ENOG4108V3E phosphoribosylglycinamide formyltransferase CEQ19_17510 ENOG4105C12 Phosphoribosylglycinamide synthetase CEQ19_17540 ENOG4105C4R Atp-dependent dna helicase CEQ19_17570 ENOG4108W2Y isochorismatase CEQ19_17580 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_17585 ENOG4108UMI ABC transporter, permease CEQ19_17590 ENOG4105D01 (LipO)protein CEQ19_17610 ENOG410834F Transcriptional regulator CEQ19_17635 ENOG4105CBD Diacylglycerol kinase CEQ19_17640 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CEQ19_17645 ENOG4108JPW Aminotransferase CEQ19_17655 ENOG4105C26 Dehydrogenase CEQ19_17660 ENOG4105KPY Small multidrug resistance protein CEQ19_17680 ENOG4105D9N nucleoside CEQ19_17685 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CEQ19_17700 ENOG4108W15 Protein of unknown function (DUF1456) CEQ19_17715 ENOG4105DTQ mandelate racemase muconate lactonizing CEQ19_17725 ENOG4105DFD Na H antiporter CEQ19_17745 ENOG4105D3R alkyl hydroperoxide reductase CEQ19_17750 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) CEQ19_17760 ENOG4107W7X Aldolase CEQ19_17765 ENOG4105EHG Permease protein CEQ19_17770 ENOG4105DQ5 transport system permease protein CEQ19_17775 ENOG4108V5C ABC transporter CEQ19_17805 ENOG4106UIA CEQ19_17810 ENOG4106UIA CEQ19_17845 ENOG4105BZU Histidine kinase CEQ19_17865 ENOG410756H nucleotidyltransferase CEQ19_17870 ENOG4105D2S major facilitator superfamily CEQ19_17885 ENOG4105E5Q amino acid AbC transporter CEQ19_17890 ENOG4105EAB amino acid AbC transporter CEQ19_17905 ENOG4105C8Q Methyl-accepting chemotaxis CEQ19_17910 ENOG4105C8Q Methyl-accepting chemotaxis CEQ19_17920 ENOG4105CI1 PTS System CEQ19_17950 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CEQ19_17965 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CEQ19_17980 ENOG4105C5H ABC transporter CEQ19_18005 ENOG41062JF Transcriptional regulator CEQ19_18025 ENOG4105DEU major facilitator superfamily CEQ19_18040 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) CEQ19_18055 ENOG4108N0M stress protein CEQ19_18060 ENOG4106FN3 tellurium resistance protein CEQ19_18065 ENOG4106FN3 tellurium resistance protein CEQ19_18070 ENOG4107TS3 membrane protein, TerC CEQ19_18075 ENOG4108TTB tellurium resistance protein CEQ19_18095 ENOG4105KJF protein tyrosine phosphatase CEQ19_18105 ENOG4107U9T Pfam:Ribonuclease_BN CEQ19_18115 ENOG4105C59 p-type ATPase CEQ19_18120 ENOG4108IPJ Membrane CEQ19_18140 ENOG4107ZTW SNARE associated Golgi CEQ19_18155 ENOG410606W general stress protein CEQ19_18160 ENOG4105UPD Calcium Proton CEQ19_18200 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CEQ19_18205 ENOG4105VTR Integrase CEQ19_18210 ENOG4108IMY Transcriptional regulator CEQ19_18520 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) CEQ19_18530 ENOG4108JUB Transcriptional regulator CEQ19_18540 ENOG4108IQI permease CEQ19_18575 ENOG4105CSV Glutaminase CEQ19_18590 ENOG4108A04 Beta-lactamase CEQ19_18605 ENOG4105CKK Glycosyl transferase, family 2 CEQ19_18615 ENOG4107QQG Dehydrogenase CEQ19_18620 ENOG4105C3I Nad-dependent epimerase dehydratase CEQ19_18640 ENOG4105F1A Pyruvate formate-lyase CEQ19_18660 ENOG4105CI2 imidazolone-5-propionate hydrolase CEQ19_18665 ENOG4105ECP epimerase CEQ19_18695 ENOG41067AE Membrane-bound metal-dependent hydrolase CEQ19_18700 ENOG4105CEN a g-specific adenine glycosylase CEQ19_18705 ENOG4106BXE CEQ19_18725 ENOG4105BZ1 (ABC) transporter CEQ19_18730 ENOG4107NBY Membrane CEQ19_18735 ENOG4105CBC glutamate synthase CEQ19_18745 ENOG4108IUW ABC transporter CEQ19_18765 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CEQ19_18770 ENOG4105G5W regulator Fur family CEQ19_18890 ENOG4108JQC penicillin-binding protein 1A CEQ19_18895 ENOG4107ZQN disulfide bond CEQ19_18905 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CEQ19_18915 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CEQ19_18920 ENOG4105BZU Histidine kinase CEQ19_18930 ENOG4105CYN Serine protein kinase CEQ19_18955 ENOG4105C94 Transporter CEQ19_18970 ENOG4105DZ6 Band 7 protein CEQ19_18980 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CEQ19_18990 ENOG4105D4T Citrate transporter CEQ19_19010 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator CEQ19_19015 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_19020 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CEQ19_19025 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component CEQ19_19030 ENOG4105BZ7 extracellular solute-binding protein family 1 CEQ19_19035 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) CEQ19_19040 ENOG4108STX response regulator CEQ19_19045 ENOG4105US7 Histidine kinase CEQ19_19070 ENOG4108MRH transcriptional regulatory protein CEQ19_19080 ENOG4105C6K Malic enzyme CEQ19_19090 ENOG4108UZ3 Transporter CEQ19_19095 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEQ19_19105 ENOG4105BZU Histidine kinase CEQ19_19110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_19120 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) CEQ19_19125 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) CEQ19_19130 ENOG4108JB9 formate dehydrogenase CEQ19_19150 ENOG4105CUB amino acid CEQ19_19160 ENOG4105C59 p-type ATPase CEQ19_19165 ENOG4105DAP Nicotinate phosphoribosyltransferase CEQ19_19200 ENOG41073R8 VanW family CEQ19_19205 ENOG4108KGH TRANSCRIPTIONal CEQ19_19210 ENOG4105D9N nucleoside CEQ19_19215 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CEQ19_19220 ENOG4105C37 (CBS) domain CEQ19_19225 ENOG4108IJ0 Aspartate ammonia-lyase CEQ19_19230 ENOG4105DAA L-lactate CEQ19_19245 ENOG4105DUX Transporter CEQ19_19250 ENOG4108MES Periplasmic binding protein CEQ19_19255 ENOG4105DQ5 transport system permease protein CEQ19_19260 ENOG4108IHU transport system permease protein CEQ19_19265 ENOG4105E0A ABC, transporter CEQ19_19270 ENOG4105DMQ Methyltransferase CEQ19_19290 ENOG4107T89 von Willebrand factor, type A CEQ19_19295 ENOG4105GMT ATPase associated with various cellular activities aaa_5 CEQ19_19300 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CEQ19_19315 ENOG4105BZU Histidine kinase CEQ19_19320 ENOG4105D5Q Arginine ornithine antiporter CEQ19_19325 ENOG4107414 GntR family transcriptional regulator CEQ19_19330 ENOG4105C5Y PTS System CEQ19_19335 ENOG4105CG3 alpha amylase, catalytic region CEQ19_19350 ENOG4105E1K spore germination protein CEQ19_19360 ENOG4105CRN Aminoglycoside phosphotransferase CEQ19_19365 ENOG4105BZG amino acid carrier protein CEQ19_19370 ENOG4105CDA abc transporter atp-binding protein CEQ19_19375 ENOG4105CT1 (ABC) transporter CEQ19_19380 ENOG4105EAD ABC transporter CEQ19_19385 ENOG4105DRP amino acid AbC transporter CEQ19_19390 ENOG4108IQI permease CEQ19_19415 ENOG4105D29 Helix-turn-helix type 11 domain protein CEQ19_19420 ENOG4105NAE bifunctional deaminase-reductase domain protein CEQ19_19425 ENOG4105BZU Histidine kinase CEQ19_19440 ENOG4105CHH sulfate transporter CEQ19_19445 ENOG41068KF Universal stress protein CEQ19_19455 ENOG4105DEF Extracellular solute-binding protein, family 5 CEQ19_19465 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ19_19470 ENOG4108JQ7 (ABC) transporter CEQ19_19480 ENOG4105CXY transporter CEQ19_19485 ENOG41067TZ transcriptional regulator, MarR family CEQ19_19495 ENOG4105ETE Transcriptional regulator (LacI family CEQ19_19500 ENOG4108RVA ribokinase CEQ19_19510 ENOG4105C2J ABC transporter CEQ19_19515 ENOG4105CNN ABC, transporter CEQ19_19520 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ19_19525 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEQ19_19585 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) CEQ19_19590 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CEQ19_19595 ENOG41069ER domain protein CEQ19_19600 ENOG4105VZ8 Transcriptional regulator CEQ19_19605 ENOG4107D63 CEQ19_19615 ENOG4105DUX Transporter CEQ19_19635 ENOG4105C85 amino acid CEQ19_19640 ENOG4105C7N Xanthine uracil vitamin C permease CEQ19_19680 ENOG4105BZ9 Cytochrome C oxidase, subunit I CEQ19_19685 ENOG4105E2S oxidase) subunit II CEQ19_19690 ENOG4108IQI permease CEQ19_19705 ENOG4106CAD Protein of unknown function (DUF3311) CEQ19_19710 ENOG4105E1V na solute symporter CEQ19_19725 ENOG4108NHD germination protein CEQ19_19735 ENOG4105CE1 Ferrous iron transport protein b CEQ19_19740 ENOG4105CE1 Ferrous iron transport protein b CEQ19_19745 ENOG4105CE1 Ferrous iron transport protein b CEQ19_19750 ENOG4105CVA phosphate CEQ19_19755 ENOG4105C8U phosphate abc transporter CEQ19_19760 ENOG4105E2Z phosphate ABC transporter (Permease CEQ19_19885 ENOG41080XQ Signal transduction protein with cbs domains CEQ19_19910 ENOG4105ETU transcriptional activator (TenA CEQ19_19920 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CEQ19_19930 ENOG4108VEU Thiamine monophosphate synthase CEQ19_19935 ENOG41080HI glycine oxidase CEQ19_19950 ENOG4105D06 uba thif-type nad fad binding protein CEQ19_19955 ENOG4105DWF phosphomethylpyrimidine kinase CEQ19_20010 ENOG4108INS Transcriptional regulator CEQ19_20025 ENOG4105C7N Xanthine uracil vitamin C permease CEQ19_20055 ENOG4105C5Y PTS System CEQ19_20115 ENOG4107Y03 Nitroreductase CEQ19_20120 ENOG4105ED1 spovr family CEQ19_20150 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase CEQ19_20155 ENOG4105XTG Pfam:DUF156 CEQ19_20160 ENOG4105VFE sira family CEQ19_20165 ENOG4107TPS domain protein CEQ19_20170 ENOG4105VFE sira family CEQ19_20175 ENOG41085GJ domain protein CEQ19_20185 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase CEQ19_20190 ENOG41087NI Sulfite exporter TauE/SafE CEQ19_20200 ENOG4108KGH TRANSCRIPTIONal CEQ19_20230 ENOG4105EMD TRANSCRIPTIONal CEQ19_20235 ENOG4105VCP PTS System CEQ19_20240 ENOG4105VZJ PTS System CEQ19_20260 ENOG41069ER domain protein CEQ19_20265 ENOG4107RBB ABC transporter, permease CEQ19_20270 ENOG4105C19 ABC transporter CEQ19_20300 ENOG4105WEF catalase CEQ19_20335 ENOG4107T5V SNARE associated Golgi CEQ19_20375 ENOG4105CUB amino acid CEQ19_20380 ENOG4107RWR Sodium hydrogen exchanger CEQ19_20390 ENOG4106KNT transcriptional regulator CEQ19_20425 ENOG4108PCN EamA-like transporter family CEQ19_20430 ENOG4108YXU transcriptional regulator AsnC family CEQ19_20440 ENOG4105KPY Small multidrug resistance protein CEQ19_20445 ENOG4105KPY Small multidrug resistance protein CEQ19_20470 ENOG4105NF4 modulator of drug activity CEQ19_20475 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CEQ19_20480 ENOG4105E5W Transporter CEQ19_20490 ENOG4107RKG DJ-1/PfpI family CEQ19_20495 ENOG4105CH6 catalase CEQ19_20505 ENOG4105D5Q Arginine ornithine antiporter CEQ19_20510 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) CEQ19_20520 ENOG4105C26 Dehydrogenase CEQ19_20540 ENOG4105BZ1 (ABC) transporter CEQ19_20560 ENOG4105DRP amino acid AbC transporter CEQ19_20565 ENOG4105CDA abc transporter atp-binding protein CEQ19_20580 ENOG410839P CEQ19_20615 ENOG4107FQX Alpha-acetolactate decarboxylase CEQ19_20650 ENOG4105D4P Coproporphyrinogen iii oxidase CEQ19_20670 ENOG4105CHH sulfate transporter CEQ19_20710 ENOG4106AKK s-layer domain-containing protein CEQ19_20720 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CEQ19_20725 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CEQ19_20745 ENOG4105CGU Enoyl-CoA hydratase CEQ19_20765 ENOG4105DER m42 family CEQ19_20785 ENOG4105CTU Proline racemase CEQ19_20825 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ19_20835 ENOG4108JQ7 (ABC) transporter CEQ19_20845 ENOG4105PKS Excinuclease abc c subunit domain protein CEQ19_20880 ENOG4105CSH Transporter CEQ19_20890 ENOG4108MRH transcriptional regulatory protein CEQ19_20940 ENOG4105CDU Replicative dna helicase CEQ19_20990 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ19_21040 ENOG4107P5I polyketide synthase CEQ19_21045 ENOG4108IG5 Transcriptional regulator CEQ19_21065 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase CEQ19_21085 ENOG4105CMT Dihydroxyacetone kinase CEQ19_21095 ENOG4105CMT Dihydroxyacetone kinase CEQ19_21100 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) CEQ19_21105 ENOG410847I Transcriptional regulator, BadM Rrf2 family CEQ19_21140 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase CEQ19_21220 ENOG4105WN5 stage II sporulation protein CEQ19_21230 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ19_21240 ENOG4108MJI response regulator CEQ19_21245 ENOG4105BZU Histidine kinase CEQ19_21250 ENOG4105BZU Histidine kinase CEQ19_21275 ENOG4105K8R UPF0145 protein CEQ19_21310 ENOG4107VRP DNA repair exonuclease CEQ19_21315 ENOG4106D4I domain protein CEQ19_21320 ENOG4105D7V transposase CEQ19_21335 ENOG4108IND Tetr family transcriptional regulator CEQ19_21340 ENOG4105EQ0 Major Facilitator superfamily CEQ19_21365 ENOG4108MUZ hydrolase CEQ19_21385 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator CEQ19_21400 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CEQ19_21420 ENOG4105EMN RNA polymerase sigma factor CEQ19_21445 ENOG4105C57 major facilitator superfamily CEQ19_21450 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ19_21460 ENOG4105EEM helicase CEQ19_21465 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CEQ19_21495 ENOG4105K59 histidine triad (HIT) protein CEQ19_21535 ENOG410905X membrane-flanked domain protein CEQ19_21580 ENOG410905X membrane-flanked domain protein CEQ19_21585 ENOG4105CKV Membrane CEQ19_21590 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation CEQ19_21595 ENOG4105BZ4 penicillin-binding protein CEQ19_21600 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) CEQ19_21610 ENOG4105C1Q protoporphyrinogen oxidase CEQ19_21635 ENOG4105NA0 Transcriptional regulator CEQ19_21650 ENOG4105ECB domain protein CEQ19_21680 ENOG4106AXD CEQ19_21685 ENOG4108RQ5 Beta-lactamase domain-containing protein CEQ19_21690 ENOG4105DF9 Lipoate-protein, ligase CEQ19_21700 ENOG4105CEY Amp-dependent synthetase and ligase CEQ19_21730 ENOG4105CNA YD repeat protein CEQ19_21780 ENOG4105ENX hydrolase CEQ19_21790 ENOG4107RN3 metallophosphoesterase CEQ19_21795 ENOG4107TVP HD domain protein CEQ19_21805 ENOG4108AEY RNA polymerase sigma factor CEQ19_21810 ENOG41086D8 Transcriptional regulator CEQ19_21830 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_21855 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 CEQ19_21860 ENOG4105C8Q Methyl-accepting chemotaxis CEQ19_21880 ENOG4105ZU5 s-layer protein CEQ19_21885 ENOG4107QP3 malate synthase g CEQ19_21900 ENOG4105VEQ Cold shock protein CEQ19_21915 ENOG4105XVF Competence transcription factor CEQ19_21930 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination CEQ19_21935 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation CEQ19_21980 ENOG4105ERH Fumarylacetoacetate hydrolase CEQ19_22005 ENOG4105CAQ asparagine synthetase CEQ19_22010 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) CEQ19_22015 ENOG4105CH6 catalase CEQ19_22020 ENOG4105BZU Histidine kinase CEQ19_22045 ENOG4105QNR S1 RNA binding domain protein CEQ19_22055 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CEQ19_22065 ENOG4107AYK membrAne CEQ19_22070 ENOG41073B9 CEQ19_22080 ENOG4108KP7 hydrolase CEQ19_22095 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ19_22125 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CEQ19_22130 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEQ19_22145 ENOG4105C31 Tryptophanyl-tRNA synthetase CEQ19_22165 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ19_22170 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ19_22180 ENOG4108JQ7 (ABC) transporter CEQ19_22185 ENOG4105UQX Mate efflux family protein CEQ19_22210 ENOG4108ZCF integral membrane protein CEQ19_22220 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CEQ19_22230 ENOG4105DPN Oligoendopeptidase f CEQ19_22245 ENOG4108Z18 K06886 hemoglobin CEQ19_22250 ENOG4105MIX Adenylate cyclase CEQ19_22265 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) CEQ19_22270 ENOG4105EMS pseudouridine synthase CEQ19_22300 ENOG4105K64 Glycosyl transferase, family 2 CEQ19_22320 ENOG4107TVC Glycosyl transferase, family 2 CEQ19_22340 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CEQ19_22345 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase CEQ19_22355 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase CEQ19_22405 ENOG4108WVJ 2'-5' rna ligase CEQ19_22430 ENOG4105CK7 Sodium proline symporter CEQ19_22445 ENOG4105CRQ synthase (Component I) CEQ19_22450 ENOG4105DDQ anthranilate synthase CEQ19_22545 ENOG4105C7S Dehydrogenase CEQ19_22555 ENOG4105VZ8 Transcriptional regulator CEQ19_22615 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) CEQ19_22630 ENOG4105DZ1 carboxypeptidase CEQ19_22635 ENOG4105VFR signal peptidase CEQ19_22670 ENOG4105C26 Dehydrogenase CEQ19_22675 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_22680 ENOG4105F38 ABC transporter, permease CEQ19_22685 ENOG4105D38 putrescine abc transporter CEQ19_22690 ENOG4107RUE extracellular solute-binding protein family 1 CEQ19_22700 ENOG4105EYF MMPL domain protein CEQ19_22710 ENOG4108YBP pseudouridine synthase CEQ19_22720 ENOG4105K4I Scp-like extracellular CEQ19_22725 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CEQ19_22730 ENOG4105CQB FAD linked oxidase domain protein CEQ19_22745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_22750 ENOG4105BZU Histidine kinase CEQ19_22755 ENOG4105JXH GntR family transcriptional regulator CEQ19_22775 ENOG4106A3R peptidase CEQ19_22785 ENOG4108QTI )-transporter CEQ19_22790 ENOG4107TS3 membrane protein, TerC CEQ19_22795 ENOG4105CZN Potassium uptake protein CEQ19_22800 ENOG410681C small acid-soluble spore protein CEQ19_22805 ENOG4108Z7G MaoC domain protein dehydratase CEQ19_22825 ENOG4105CHR reductase CEQ19_22835 ENOG4105MWK D-amino acid dehydrogenase, small subunit CEQ19_22860 ENOG4105C4Y ABC transporter CEQ19_22875 ENOG4108KAZ Involved in phosphonate degradation (By similarity) CEQ19_22890 ENOG4105E98 transcriptional regulator DeoR family CEQ19_22920 ENOG4105PXI polysaccharide deacetylase CEQ19_22930 ENOG4105BZU Histidine kinase CEQ19_22935 ENOG41090MY MarR family Transcriptional regulator CEQ19_22945 ENOG4106DF1 CEQ19_22955 ENOG4105BZU Histidine kinase CEQ19_22965 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CEQ19_22970 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CEQ19_23015 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) CEQ19_23035 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEQ19_23040 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family CEQ19_23045 ENOG4105CZV ABC transporter CEQ19_23055 ENOG4105CJ1 ABC, transporter CEQ19_23095 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CEQ19_23100 ENOG4105EA8 2-Nitropropane dioxygenase CEQ19_23105 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD CEQ19_23115 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CEQ19_23140 ENOG4105NQC Flavodoxin CEQ19_23180 ENOG4107QMU Mate efflux family protein CEQ19_23185 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) CEQ19_23215 ENOG4105CZN Potassium uptake protein CEQ19_23220 ENOG41063Y9 CEQ19_23225 ENOG4105KBJ sporulation protein ytfj CEQ19_23255 ENOG4105CM2 brancheD-chain amino acid aminotransferase CEQ19_23260 ENOG4105C7K acetolactate synthase CEQ19_23265 ENOG4108ZP8 Acetolactate synthase small subunit CEQ19_23270 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase CEQ19_23280 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CEQ19_23305 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CEQ19_23340 ENOG4107RVV histidinol phosphate phosphatase, hisj family CEQ19_23355 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase CEQ19_23360 ENOG4105E0M Sulfatase CEQ19_23370 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CEQ19_23390 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CEQ19_23395 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) CEQ19_23405 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CEQ19_23410 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein CEQ19_23415 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein CEQ19_23425 ENOG4105C8J )-transporter CEQ19_23445 ENOG4105DFD Na H antiporter CEQ19_23465 ENOG4105ENE Histidine kinase CEQ19_23470 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ19_23490 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) CEQ19_23515 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEQ19_23540 ENOG4105CJ3 phosphate transporter CEQ19_23545 ENOG4107GRR phosphate transport regulator CEQ19_23550 ENOG4105BZ4 penicillin-binding protein CEQ19_23575 ENOG4105I3N Conserved Protein CEQ19_23590 ENOG4105BZU Histidine kinase CEQ19_23630 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEQ19_23635 ENOG4105DZ1 carboxypeptidase CEQ19_23640 ENOG4108JIC nucleoside recognition domain protein CEQ19_23650 ENOG4105FE9 pseudouridine synthase CEQ19_23660 ENOG4107TWT Cytochrome c biogenesis protein CEQ19_23665 ENOG4105CRE cytochrome C CEQ19_23670 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_23675 ENOG4105BZU Histidine kinase CEQ19_23680 ENOG4108WBT adenosyltransferase CEQ19_23695 ENOG4108SAX Membrane CEQ19_23705 ENOG4105T7X CEQ19_23710 ENOG4105C9U ATP-dependent DNA helicase RecQ CEQ19_23715 ENOG4105I7S Abortive infection protein CEQ19_23730 ENOG4107X2D transcriptional regulator, merr family CEQ19_23735 ENOG4108S6Z Negative regulator of genetic competence CEQ19_23760 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase CEQ19_23765 ENOG4105HDK L-asparaginase CEQ19_23800 ENOG4105S2F CEQ19_23805 ENOG41065D1 CEQ19_23835 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) CEQ19_23850 ENOG4105XXQ heptaprenyl diphosphate synthase component I CEQ19_23860 ENOG4105EAH synthase CEQ19_23880 ENOG4105CIH Imidazole acetol-phosphate transaminase CEQ19_23885 ENOG41068YB TPR repeat-containing protein CEQ19_23900 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) CEQ19_23905 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) CEQ19_23910 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit CEQ19_23945 ENOG4108JYZ YitT family CEQ19_23955 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase CEQ19_23970 ENOG4105FJR Lmbe family CEQ19_23975 ENOG4105CPK Glycosyl transferase (Group 1 CEQ19_24015 ENOG4105DVT helicase CEQ19_24020 ENOG4105YAC CEQ19_24040 ENOG4105CSM endonuclease III CEQ19_24050 ENOG4105BZ4 penicillin-binding protein CEQ19_24115 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) CEQ19_24125 ENOG4105DVT helicase CEQ19_24130 ENOG4105CTD carboxy-peptidase CEQ19_24145 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CEQ19_24155 ENOG4105C2W permease CEQ19_24160 ENOG4105DHF Membrane CEQ19_24170 ENOG410890F Dynamin family CEQ19_24180 ENOG4108W0I acetyltransferase CEQ19_24190 ENOG4105KHC sulfurtransferase CEQ19_24215 ENOG4106032 Glutathionylspermidine synthase CEQ19_24280 ENOG4105CPK Glycosyl transferase (Group 1 CEQ19_24295 ENOG4108SZE gCN5-related N-acetyltransferase CEQ19_24315 ENOG41081VK Ribonuclease CEQ19_24380 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CEQ19_24395 ENOG4107RWR Sodium hydrogen exchanger CEQ19_24400 ENOG4105CN5 Metallo-Beta-Lactamase CEQ19_24405 ENOG4108Z5V transcriptional regulator, merr family CEQ19_24415 ENOG4105H67 Protein of unknown function (DUF421) CEQ19_24420 ENOG41080C8 DUF218 domain CEQ19_24475 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) CEQ19_24485 ENOG4107R0U MotA TolQ exbB proton channel CEQ19_24490 ENOG4105ER2 Ompa motb domain protein CEQ19_24495 ENOG4107YTP response regulator receiver protein CEQ19_24500 ENOG4105CBS Chea signal transduction histidine kinase CEQ19_24505 ENOG4105CBS Chea signal transduction histidine kinase CEQ19_24510 ENOG4105DD5 Flagellar motor switch protein CEQ19_24525 ENOG4105BZU Histidine kinase CEQ19_24545 ENOG4105E1Q flagellar hook-associated protein CEQ19_24570 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CEQ19_24575 ENOG4108ZC9 flagellar basal-body rod protein flgc CEQ19_24580 ENOG41075Z6 flagellar hook-basal body complex protein fliE CEQ19_24590 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEQ19_24625 ENOG4105BZE flagellar hook protein, FlgE CEQ19_24655 ENOG4105K64 Glycosyl transferase, family 2 CEQ19_24700 ENOG4105I03 Flagellin CEQ19_24705 ENOG4105E4C Lytic transglycosylase catalytic CEQ19_24720 ENOG4105DD5 Flagellar motor switch protein CEQ19_24730 ENOG4105CN7 Flagellar biosynthetic protein FliP CEQ19_24735 ENOG4105VS8 Flagellar biosynthetic protein fliq CEQ19_24745 ENOG4105D00 flagellar biosynthetic protein flhB CEQ19_24750 ENOG4105D7B Flagellar biosynthesis protein flha CEQ19_24760 ENOG4105KTQ flagellar basal-body rod protein CEQ19_24765 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CEQ19_24790 ENOG4108RZE Tetr family transcriptional regulator CEQ19_24810 ENOG4105KAC Antibiotic biosynthesis monooxygenase CEQ19_24835 ENOG4105DUM transcriptional regulator, lysR family CEQ19_24840 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ19_24845 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CEQ19_24850 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component CEQ19_24855 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) CEQ19_24895 ENOG4105CVJ phosphoglycerate mutase CEQ19_24925 ENOG4105CAQ asparagine synthetase CEQ19_24945 ENOG4105PGM cation diffusion facilitator family transporter CEQ19_24955 ENOG4105DRR Transcriptional regulator, GntR family CEQ19_24960 ENOG4108UZ3 Transporter CEQ19_24965 ENOG4105CKI cobalamin synthesis protein CEQ19_24975 ENOG4108PJD permease CEQ19_24990 ENOG4105DFD Na H antiporter CEQ19_24995 ENOG4105C9Q fumarate hydratase class II CEQ19_25025 ENOG4105EC3 peptidase S51, dipeptidase E CEQ19_25045 ENOG4107QIV Cytochrome c biogenesis protein CEQ19_25080 ENOG4106BRA Membrane CEQ19_25120 ENOG4105CJ1 ABC, transporter CEQ19_25140 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) CEQ19_25150 ENOG4108IJ0 Aspartate ammonia-lyase CEQ19_25155 ENOG4105C6K Malic enzyme CEQ19_25230 ENOG4105FVX CEQ19_25270 ENOG4105CSR polyphosphate kinase 2 CEQ19_25295 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CEQ19_25305 ENOG4105EU0 Major facilitator Superfamily CEQ19_25310 ENOG4105C6T cysteine synthase CEQ19_25330 ENOG4105C8J )-transporter CEQ19_25340 ENOG4105X5K response regulator receiver protein CEQ19_25345 ENOG4105H67 Protein of unknown function (DUF421) CEQ19_25365 ENOG4106KE4 Dehydrogenase CEQ19_25385 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) CEQ19_25390 ENOG4105CHR reductase CEQ19_25395 ENOG4105CM2 brancheD-chain amino acid aminotransferase CEQ19_25400 ENOG4105C7K acetolactate synthase CEQ19_25405 ENOG4108ZP8 Acetolactate synthase small subunit CEQ19_25410 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase CEQ19_25420 ENOG4105C7B Threonine dehydratase CEQ19_25445 ENOG4105C6X Major Facilitator CEQ19_25450 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CEQ19_25460 ENOG4105DY9 regulatoR CEQ19_25465 ENOG4105CYC Transferase CEQ19_25485 ENOG4105F6J Alpha beta hydrolase fold CEQ19_25495 ENOG4108J59 Extracellular solute-binding protein, family 5 CEQ19_25530 ENOG41068WN CEQ19_25555 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) CEQ19_25560 ENOG4105C72 UPF0176 protein CEQ19_25570 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CEQ19_25605 ENOG4107RHR regulatoR CEQ19_25615 ENOG4105D9N nucleoside CEQ19_25620 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) CEQ19_25655 ENOG4107RAQ aminopeptidase CEQ19_25660 ENOG4107STQ Multicopper oxidase CEQ19_25705 ENOG4108T5E Copper resistance protein CEQ19_25710 ENOG4105KTB nuclear export factor GLE1 CEQ19_25720 ENOG4107RT3 EamA-like transporter family CEQ19_25725 ENOG4105GZI Transcriptional regulator CEQ19_25730 ENOG4108Z40 Transcriptional regulator CEQ19_25735 ENOG4107ZXU DSBA oxidoreductase CEQ19_25740 ENOG4108TVJ Nitroreductase CEQ19_25750 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) CEQ19_25755 ENOG4106F5Q Membrane CEQ19_25760 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CEQ19_25770 ENOG4105CKI cobalamin synthesis protein CEQ19_25790 ENOG4108Z7G MaoC domain protein dehydratase CEQ19_25795 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CEQ19_25810 ENOG4105C0Z ABC transporter CEQ19_25815 ENOG4108IV0 ABC, transporter CEQ19_25820 ENOG4105C32 Amino acid ABC transporter (Permease) CEQ19_25830 ENOG4105SKE transcriptional Regulator LysR family CEQ19_25850 ENOG4105YGB Transcriptional regulator CEQ19_25860 ENOG4105C4M (Ubiquinol oxidase) subunit I CEQ19_25865 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CEQ19_25870 ENOG4108JJ9 ABC, transporter CEQ19_25875 ENOG4108JJ8 (ABC) transporter CEQ19_25930 ENOG4105EFI regulatoR CEQ19_25935 ENOG4105BZU Histidine kinase CEQ19_25955 ENOG41075D4 Aminoglycoside 6-adenylyltransferase CEQ19_25960 ENOG4108ZJ4 polysaccharide deacetylase CEQ19_25990 ENOG4105D6E homoserine dehydrogenase CEQ19_26015 ENOG4108KGH TRANSCRIPTIONal CEQ19_26025 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ19_26030 ENOG4105BZU Histidine kinase CEQ19_26035 ENOG4107VMI polysaccharide deacetylase CEQ19_26045 ENOG4105KT7 mgtC SapB transporter CEQ19_26050 ENOG4105VRR gCN5-related N-acetyltransferase CEQ19_26060 ENOG4105DUU IucA IucC family protein CEQ19_26065 ENOG4105CEY Amp-dependent synthetase and ligase CEQ19_26080 ENOG4108WBH protein TIM barrel CEQ19_26085 ENOG4105YWU small acid-soluble spore protein CEQ19_26095 ENOG4108ZUB Lysine exporter protein (Lyse ygga) CEQ19_26150 ENOG4105KRN Transcriptional regulator, abrb family CEQ19_26160 ENOG4105YVS arsR family transcriptional regulator CEQ19_26165 ENOG4107SET aldo keto reductase CEQ19_26170 ENOG4107XZQ multidrug resistance protein CEQ19_26195 ENOG4105C8Q Methyl-accepting chemotaxis CEQ19_26215 ENOG4108K88 Membrane CEQ19_26220 ENOG4108WPJ Ferritin-like domain CEQ19_26235 ENOG4105DEN Luciferase family CEQ19_26255 ENOG4107QM2 Aldo Keto reductase CEQ19_26260 ENOG4105CKI cobalamin synthesis protein CEQ19_26340 ENOG4105DSE periplasmic solute binding protein CEQ19_26350 ENOG4105K4T epimerase CEQ19_26360 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEQ19_26385 ENOG4105CVJ phosphoglycerate mutase CEQ19_26405 ENOG4107T5V SNARE associated Golgi CEQ19_26420 ENOG4108PJD permease CEQ19_26430 ENOG4108S4H thioesterase Superfamily protein CEQ19_26445 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CEQ19_26465 ENOG4105SXS Protein of unknown function (DUF456) CEQ19_26470 ENOG4105C37 (CBS) domain CEQ19_26490 ENOG4108Z7R Chaperone CsaA CEQ19_26510 ENOG4108ZRV stage ii sporulation protein p CEQ19_26520 ENOG4108VXD carboxy-peptidase CEQ19_26530 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) CEQ19_26555 ENOG4108X4Q Hydrolase CEQ19_26565 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEQ19_26570 ENOG4107RBS Methyltransferase CEQ19_26585 ENOG41087PP glycosyltransferase MGT family CEQ19_26590 ENOG4108JYZ YitT family CEQ19_26595 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEQ19_26625 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) CEQ19_26685 ENOG4105KBJ sporulation protein ytfj CEQ19_26710 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) CEQ19_26730 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) CEQ19_26735 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase CEQ19_26745 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CEQ19_26750 ENOG4105EMN RNA polymerase sigma factor CEQ19_26775 ENOG4108V06 Glutathione peroxidase CEQ19_26790 ENOG4105C7R Atpase associated with various cellular activities aaa_3 CEQ19_26810 ENOG4108IUE nitrate reductase beta subunit CEQ19_26815 ENOG4105R3A Nitrate reductase CEQ19_26840 ENOG4107V6Q Cyclic nucleotide-binding domain CEQ19_26845 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CEQ19_26850 ENOG4105D06 uba thif-type nad fad binding protein CEQ19_26855 ENOG4105CVM Molybdenum cofactor synthesis domain protein CEQ19_26860 ENOG4108ZAF Molybdopterin CEQ19_26890 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein CEQ19_26895 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein CEQ19_26900 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CEQ19_26905 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit CEQ19_26910 ENOG4108IFG nitrite reductase, (NAD(P)H) CEQ19_26915 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) CEQ19_26950 ENOG4105MCT stage V sporulation protein S CEQ19_26970 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase CEQ19_26990 ENOG4105C5H ABC transporter CEQ19_27005 ENOG4108UUM single-stranded DNA-binding protein CEQ19_27035 ENOG4107YX5 Pfam:DUF548 CEQ19_27040 ENOG4105C75 arginyL-tRNA synthetase CEQ19_27070 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) CEQ19_27090 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) CEQ19_27095 ENOG4105C5S asparaginyl-tRNA synthetase CEQ19_27115 ENOG4105EC2 ftsk spoIIIe CEQ19_27225 ENOG4105BZW Glycerate kinase CEQ19_27230 ENOG4107QPK )-transporter CEQ19_27235 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ19_27240 ENOG41062D9 Histidine kinase CEQ19_27255 ENOG4105C8J )-transporter CEQ19_27275 ENOG4107XGZ Hydrolase CEQ19_27280 ENOG4105CY2 Citrate transporter CEQ19_27285 ENOG4105C0A alcohol dehydrogenase CEQ19_27300 ENOG4105KD7 acetyltransferase CEQ19_27330 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 CEQ19_27350 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) CEQ19_27365 ENOG4107RVG penicillin-binding protein CEQ19_27370 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) CEQ19_27375 ENOG4105E9Q Acyl-transferase CEQ19_27380 ENOG4108UT2 hemolysin iii CEQ19_27390 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CEQ19_27405 ENOG4108RCR degv family CEQ19_27410 ENOG4105E8R UPF0173 metal-dependent hydrolase CEQ19_27415 ENOG4108KF3 Electron transport protein SCO1 SenC CEQ19_27420 ENOG4107Y70 Heat shock protein CEQ19_27425 ENOG4105CAQ asparagine synthetase CEQ19_27445 ENOG4108MES Periplasmic binding protein CEQ19_27450 ENOG4105F0I Aminotransferase CEQ19_27485 ENOG4105D8X mechanosensitive ion channel CEQ19_27490 ENOG4105BZU Histidine kinase CEQ19_27495 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ19_27540 ENOG4105CMG Carbohydrate kinase CEQ19_27545 ENOG4105CMG Carbohydrate kinase CEQ19_27575 ENOG4108IJ8 ABC transporter CEQ19_27580 ENOG4105E90 ABC transporter CEQ19_27615 ENOG4105C37 (CBS) domain CEQ19_27645 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CEQ19_27660 ENOG4107S4Y M20 DapE family protein YgeY CEQ19_27665 ENOG4108TSC N-acetyltransferase CEQ19_27670 ENOG4108JUB Transcriptional regulator CEQ19_27680 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CEQ19_27720 ENOG4108N23 SpoOM-related protein CEQ19_27725 ENOG410841Q phosphoesterase PA-phosphatase related protein CEQ19_27735 ENOG4105SZ6 Thioredoxin CEQ19_27750 ENOG4108IBT Inherit from COG: transposase CEQ19_27875 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CEQ19_27915 ENOG4105BZ4 penicillin-binding protein CEQ19_27920 ENOG4105CZM Major Facilitator CEQ19_27925 ENOG4105W8X HesB YadR YfhF-family protein CEQ19_27935 ENOG4105DXD 2-methylcitrate dehydratase CEQ19_27940 ENOG4105CR4 methylisocitrate lyase CEQ19_27945 ENOG4105C1G acyl-Coa dehydrogenase CEQ19_27950 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CEQ19_27960 ENOG4105N14 lysine exporter protein LysE YggA CEQ19_27965 ENOG4105E39 Enoyl-CoA hydratase CEQ19_27980 ENOG4107RFY SbcCD D subunit CEQ19_27985 ENOG4105EYH Exonuclease CEQ19_28020 ENOG4105FCD Major Facilitator CEQ19_28030 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase CEQ19_28035 ENOG4105E4F Isochorismate synthase CEQ19_28040 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CEQ19_28045 ENOG4105WQI isochorismatase CEQ19_28050 ENOG4105CEY Amp-dependent synthetase and ligase CEQ19_28055 ENOG4105WQT MbtH domain protein CEQ19_28060 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ19_28075 ENOG4105K70 DNA-binding protein CEQ19_28095 ENOG4105BZG amino acid carrier protein CEQ19_28115 ENOG4105FE9 pseudouridine synthase CEQ19_28120 ENOG4105C22 threonyL-tRNA synthetase CEQ19_28145 ENOG4107SKW Inherit from COG: Alpha beta hydrolase CEQ19_28170 ENOG4108D32 Methyltransferase CEQ19_28200 ENOG41081I9 integral membrane protein CEQ19_28215 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) CEQ19_28225 ENOG4105EYF MMPL domain protein CEQ19_28250 ENOG4105WCN acetyltransferase CEQ19_28280 ENOG4105C1Q protoporphyrinogen oxidase CEQ19_28290 ENOG41068WN CEQ19_28300 ENOG4105VEQ Cold shock protein CEQ19_28320 ENOG410667J hydrolase CEQ19_28370 ENOG4107V2S Transcriptional regulator CEQ19_28375 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEQ19_28390 ENOG4105DND Transcriptional regulator CEQ19_28395 ENOG4108RPX mosc domain containing protein CEQ19_28410 ENOG4105BZ1 (ABC) transporter CEQ19_28415 ENOG4105BZ1 (ABC) transporter CEQ19_28435 ENOG4108JCI Transcriptional regulator CEQ19_28465 ENOG4108KPJ rna polymerase sigma factor CEQ19_28495 ENOG4105F32 YngK protein CEQ19_28525 ENOG4105RD7 BadF BadG BcrA BcrD CEQ19_28535 ENOG4107STF Involved in phosphonate degradation (By similarity) CEQ19_28560 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) CEQ19_28575 ENOG4105C1J atp-dependent rna helicase CEQ19_28590 ENOG4108RZE Tetr family transcriptional regulator CEQ19_28610 ENOG41088CC tellurite resistance protein tehB CEQ19_28620 ENOG4108I0C methyltransferase CEQ19_28625 ENOG4107RA9 decarboxylase CEQ19_28630 ENOG41090HR transcriptional regulator CEQ19_28680 ENOG4105CIN aminoacyl-histidine dipeptidase CEQ19_28710 ENOG4107RF6 penicillin-binding protein CEQ19_28730 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CEQ19_28735 ENOG4105ETE Transcriptional regulator (LacI family CEQ19_28740 ENOG4105IE8 Alpha-ketoglutarate permease CEQ19_28745 ENOG4105CK5 oxidoreductase CEQ19_28770 ENOG4105D2N Aldolase CEQ19_28775 ENOG4105DH8 myo-inositol catabolism CEQ19_28805 ENOG4105VZ8 Transcriptional regulator CEQ19_28825 ENOG4108VXD carboxy-peptidase CEQ19_28845 ENOG41067SE Tetr family transcriptional regulator CEQ19_28850 ENOG4105C5H ABC transporter CEQ19_28860 ENOG4105BZU Histidine kinase CEQ19_28875 ENOG4106ANW SMI1_KNR4 CEQ19_28880 ENOG4105CEP NADH dehydrogenase CEQ19_28885 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) CEQ19_28900 ENOG4105CJ1 ABC, transporter CEQ19_28910 ENOG4107Z3H Transcriptional regulator, TetR family CEQ19_28930 ENOG4105C1G acyl-Coa dehydrogenase CEQ19_28935 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CEQ19_28940 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit CEQ19_28945 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase CEQ19_28950 ENOG4105E39 Enoyl-CoA hydratase CEQ19_28955 ENOG4107QX3 carboxylase CEQ19_28960 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CEQ19_28970 ENOG4105WCN acetyltransferase CEQ19_28975 ENOG4105DBI uridine monophosphokinase CEQ19_29005 ENOG4105T9C HD domain CEQ19_29020 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) CEQ19_29060 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CEQ19_29060 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CEQ19_29075 ENOG4105FQP Beta-lactamase CEQ19_29085 ENOG4107Y80 Major Facilitator superfamily CEQ19_29105 ENOG4105CUV Homoserine Kinase CEQ19_29140 ENOG4105CPQ Dehydrogenase CEQ19_29425 ENOG4105DHF Membrane CEQ19_29455 ENOG4106AKK s-layer domain-containing protein CEQ19_29460 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CEQ19_29490 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEQ19_29495 ENOG4105C6Y Udp-glucose 6-dehydrogenase CEQ19_29555 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) CEQ19_29585 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) CEQ19_29705 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ19_29735 ENOG4108IBT Inherit from COG: transposase CEQ19_29760 ENOG4108MEK Metal-binding protein YodA CEQ19_29775 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) CEQ19_29805 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) CEQ19_29900 ENOG4105EKQ RNA-directed DNA polymerase CEQ19_29995 ENOG4105EKQ RNA-directed DNA polymerase CEQ19_30125 ENOG4105CNU cell division protein FtsK CEQ19_30185 ENOG4105EYF MMPL domain protein