locus-tag class description FOC08_00020 ENOG4105EFC phage portal protein HK97 family FOC08_00045 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC08_00055 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FOC08_00060 ENOG4105CP7 Triose-phosphate isomerase FOC08_00085 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_00105 ENOG41090VF Stage v sporulation protein ac FOC08_00110 ENOG4105CZ3 stage V sporulation protein ad FOC08_00125 ENOG4105H67 Protein of unknown function (DUF421) FOC08_00130 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOC08_00135 ENOG4105KRI phosphocarrier protein (HPr FOC08_00145 ENOG4105CHW UPF0052 protein FOC08_00155 ENOG4108Z4K mutator MutT protein FOC08_00165 ENOG4105C3M thioredoxin reductase FOC08_00175 ENOG4108S4C acetyltransferase FOC08_00195 ENOG41086DT Membrane protein of unknown function FOC08_00205 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC08_00210 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC08_00215 ENOG4105D7V transposase FOC08_00230 ENOG4107TXC Transcriptional regulator FOC08_00255 ENOG4105HMI Membrane FOC08_00260 ENOG4105DUM transcriptional regulator, lysR family FOC08_00270 ENOG4108WS4 fmn reductase FOC08_00285 ENOG4105BZ1 (ABC) transporter FOC08_00295 ENOG4105CN1 protease FOC08_00300 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC08_00305 ENOG4105CAK Cell division ATP-binding protein ftsE FOC08_00325 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FOC08_00330 ENOG4105MS2 ribosomal subunit Interface protein FOC08_00335 ENOG4105VEQ Cold shock protein FOC08_00340 ENOG41081UC Inherit from COG: Competence protein FOC08_00355 ENOG4105KVH Transcriptional regulator FOC08_00365 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC08_00370 ENOG4108KGH TRANSCRIPTIONal FOC08_00375 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC08_00380 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC08_00385 ENOG4105ESV Glycosyl transferase, family 4 FOC08_00395 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC08_00410 ENOG410901P UPF0249 protein FOC08_00415 ENOG4105F8D glycoside hydrolase family 4 FOC08_00420 ENOG4105VCP PTS System FOC08_00425 ENOG4105CK1 PTS System FOC08_00435 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC08_00440 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) FOC08_00445 ENOG4105VCP PTS System FOC08_00455 ENOG4105VZJ PTS System FOC08_00470 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_00475 ENOG4105ECB domain protein FOC08_00480 ENOG4107RSM transcriptional regulator FOC08_00520 ENOG4105DAA L-lactate FOC08_00530 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC08_00540 ENOG4105E0M Sulfatase FOC08_00570 ENOG4105C94 Transporter FOC08_00575 ENOG41069ER domain protein FOC08_00600 ENOG4105KBK Zinc finger, swim domain protein FOC08_00605 ENOG4105C0D helicase FOC08_00635 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_00645 ENOG4107RBB ABC transporter, permease FOC08_00650 ENOG4105C19 ABC transporter FOC08_00670 ENOG4105CXY transporter FOC08_00685 ENOG4105BZU Histidine kinase FOC08_00690 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_00695 ENOG4105CMR udp-glucose 4-epimerase FOC08_00710 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC08_00715 ENOG4105EY8 ABC transporter FOC08_00770 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC08_00785 ENOG4105FRN stage II sporulation protein FOC08_00820 ENOG4106778 Protein of unknown function (DUF1146) FOC08_00825 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC08_00830 ENOG4105C8S subunit m FOC08_00835 ENOG4105D65 subunit l FOC08_00860 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC08_00865 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC08_00875 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC08_00880 ENOG4105BZU Histidine kinase FOC08_00930 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC08_00935 ENOG41062M3 atp synthase FOC08_00965 ENOG4108YZG isomerase FOC08_00980 ENOG4108VGI doxx family FOC08_00985 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC08_01000 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC08_01010 ENOG4108ZXQ stage ii sporulation protein r FOC08_01015 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC08_01020 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FOC08_01035 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC08_01040 ENOG4105CBT Fructose-1,6-bisphosphatase FOC08_01045 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FOC08_01080 ENOG4105C1G acyl-Coa dehydrogenase FOC08_01085 ENOG4105C1G acyl-Coa dehydrogenase FOC08_01090 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC08_01100 ENOG4105DF6 Fe-S oxidoreductase FOC08_01115 ENOG4105BZU Histidine kinase FOC08_01140 ENOG4105BZU Histidine kinase FOC08_01145 ENOG4105KCT ABC transporter FOC08_01150 ENOG4108M15 ABC transporter FOC08_01155 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC08_01165 ENOG4105IIU Aminopeptidase FOC08_01185 ENOG4105EMN RNA polymerase sigma factor FOC08_01195 ENOG410684U Domain of unknown function (DUF1934) FOC08_01215 ENOG4105CYW agmatinase FOC08_01225 ENOG4105DXB Major Facilitator superfamily FOC08_01230 ENOG4107SWG transcriptional regulator MERR family FOC08_01235 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC08_01240 ENOG4105BZ4 penicillin-binding protein FOC08_01245 ENOG4108XFG YwhD family FOC08_01250 ENOG4108Z4T Peptidase M50 FOC08_01255 ENOG41069HH 4-oxalocrotonate tautomerase FOC08_01260 ENOG4105DCI Phosphohydrolase FOC08_01265 ENOG4108MES Periplasmic binding protein FOC08_01270 ENOG4105E0A ABC, transporter FOC08_01275 ENOG4105EHG Permease protein FOC08_01290 ENOG4108VCI transcription factor, rsfa family FOC08_01305 ENOG4108IJ2 phosphate acetyltransferase FOC08_01320 ENOG4108VKI Cell wall hydrolase FOC08_01350 ENOG410667J hydrolase FOC08_01355 ENOG4105VCH membrane FOC08_01365 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC08_01370 ENOG4105CJ1 ABC, transporter FOC08_01375 ENOG41090WU lipolytic protein G-D-S-L family FOC08_01390 ENOG4105D6E homoserine dehydrogenase FOC08_01415 ENOG4108Y4K DNA-binding transcriptional activator FOC08_01425 ENOG4105WH1 Two component transcriptional regulator luxr family FOC08_01435 ENOG4105DWF phosphomethylpyrimidine kinase FOC08_01440 ENOG4105BZU Histidine kinase FOC08_01445 ENOG4105VCD cytoplasmic protein FOC08_01450 ENOG4105D22 carbon starvation protein FOC08_01455 ENOG4105DY9 regulatoR FOC08_01460 ENOG41079KZ Major Facilitator Superfamily FOC08_01480 ENOG4105EN6 Membrane FOC08_01485 ENOG4106YBV Methyl-accepting chemotaxis FOC08_01495 ENOG4108S4H thioesterase Superfamily protein FOC08_01505 ENOG4105JEU Glycosyl transferase, family 2 FOC08_01510 ENOG4105C5H ABC transporter FOC08_01530 ENOG4105CKK Glycosyl transferase, family 2 FOC08_01535 ENOG41067SE Tetr family transcriptional regulator FOC08_01545 ENOG4105E0X reductase FOC08_01550 ENOG4106F5Q Membrane FOC08_01565 ENOG4105DY9 regulatoR FOC08_01570 ENOG4108HRK Histidine kinase FOC08_01575 ENOG4107RGD Major Facilitator superfamily FOC08_01590 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC08_01600 ENOG4105IW1 AmiS UreI transporter FOC08_01610 ENOG4105CMR udp-glucose 4-epimerase FOC08_01615 ENOG4108UT2 hemolysin iii FOC08_01625 ENOG4105C1J atp-dependent rna helicase FOC08_01640 ENOG4105DPN Oligoendopeptidase f FOC08_01660 ENOG4105C0H protease FOC08_01665 ENOG4105Q2H domain protein FOC08_01680 ENOG4105BZU Histidine kinase FOC08_01685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_01715 ENOG4105CDU Replicative dna helicase FOC08_01725 ENOG4105BZR domain protein FOC08_01730 ENOG4108XMW Membrane FOC08_01740 ENOG4108UUM single-stranded DNA-binding protein FOC08_01750 ENOG4105C3G gtp-binding protein FOC08_01755 ENOG4105VDK protein, conserved in bacteria FOC08_01760 ENOG4105D8X mechanosensitive ion channel FOC08_01765 ENOG4108ZDA Sporulation protein YyaC FOC08_01770 ENOG4105FA0 parb-like partition protein FOC08_01775 ENOG4107QJE Chromosome Partitioning Protein FOC08_01795 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FOC08_01805 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC08_01825 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC08_01830 ENOG410848D S4 domain protein YaaA FOC08_01845 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC08_01880 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC08_01915 ENOG4105ZMH deoxynucleoside kinase FOC08_01925 ENOG4105GTG Isochorismatase FOC08_01930 ENOG4108Z6B deaminase FOC08_01940 ENOG4105C6E dna polymerase iii FOC08_01960 ENOG41067KS pro-sigma K processing FOC08_01995 ENOG4105CXN decarboxylase FOC08_02005 ENOG4105FA2 dna polymerase iii FOC08_02010 ENOG4105MA4 psp1 domain protein FOC08_02020 ENOG41060K3 Methyltransferase FOC08_02030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC08_02035 ENOG4105KRN Transcriptional regulator, abrb family FOC08_02045 ENOG4105F8V Hydrolase, tatD family FOC08_02050 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC08_02060 ENOG4105XFA sporulation peptidase YabG FOC08_02065 ENOG4105W42 Veg protein FOC08_02080 ENOG4105DFT pur operon repressor FOC08_02085 ENOG4105KME endoribonuclease L-psp FOC08_02100 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FOC08_02105 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FOC08_02115 ENOG4108JA2 transcriptioN-repair coupling factor FOC08_02120 ENOG4108M14 stage v sporulation protein t FOC08_02130 ENOG4108IY2 MazG family FOC08_02135 ENOG41082I2 s4 domain protein FOC08_02140 ENOG4105VYY sporulation protein yabp FOC08_02155 ENOG41060GV RNA binding s1 domain protein FOC08_02175 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FOC08_02180 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC08_02185 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC08_02200 ENOG4105C6T cysteine synthase FOC08_02205 ENOG4105CRQ synthase (Component I) FOC08_02210 ENOG4105DDQ anthranilate synthase FOC08_02215 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC08_02220 ENOG4105EEI dihydropteroate synthase FOC08_02225 ENOG4105KRF dihydroneopterin aldolase FOC08_02230 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC08_02240 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC08_02270 ENOG4108Z0C Uvrb UvrC protein FOC08_02285 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC08_02295 ENOG4105CTP PilT protein domain protein FOC08_02315 ENOG4105D7W serine acetyltransferase FOC08_02330 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC08_02335 ENOG4105M0M Tetracycline resistance protein FOC08_02340 ENOG4105QIV RNA polymerase FOC08_02355 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC08_02380 ENOG4107Y49 methyltransferase FOC08_02390 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FOC08_02395 ENOG4105XPM ribosomal protein FOC08_02500 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FOC08_02525 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC08_02535 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC08_02545 ENOG41067V7 50S ribosomal protein L36 FOC08_02575 ENOG4108JJB ABC transporter FOC08_02580 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC08_02585 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FOC08_02610 ENOG4105D1F ATP-binding protein FOC08_02625 ENOG4108NMV polysaccharide deacetylase FOC08_02705 ENOG4105C8B TIGR00159 family FOC08_02710 ENOG4107U5W ybbr family FOC08_02725 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FOC08_02730 ENOG4108VQT Alpha beta hydrolase fold protein FOC08_02750 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC08_02755 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FOC08_02790 ENOG4108UMI ABC transporter, permease FOC08_02795 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC08_02800 ENOG4105D01 (LipO)protein FOC08_02805 ENOG4105EE1 crotonyl-CoA reductase FOC08_02815 ENOG4105IQ5 FAD linked oxidase domain protein FOC08_02830 ENOG4105C2C drug resistance transporter, Bcr CflA FOC08_02845 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC08_02850 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC08_02855 ENOG4105C3U ABC transporter FOC08_02860 ENOG4108JQ7 (ABC) transporter FOC08_02890 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC08_02895 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC08_02905 ENOG4105II7 pyrroline-5-carboxylate reductase FOC08_02910 ENOG4107XDY Nicotinamide Mononucleotide Transporter FOC08_02920 ENOG4105E0C molybdate abc transporter FOC08_02930 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC08_02940 ENOG4105EGI Transcriptional regulator FOC08_02960 ENOG4105F6E Acyl-transferase FOC08_02980 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC08_02990 ENOG4108RE7 deoxyribonuclease FOC08_02995 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC08_03015 ENOG4105C5H ABC transporter FOC08_03030 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FOC08_03040 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC08_03045 ENOG4105C3U ABC transporter FOC08_03050 ENOG4108JQ7 (ABC) transporter FOC08_03070 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC08_03075 ENOG4105ERH Fumarylacetoacetate hydrolase FOC08_03085 ENOG4108SC4 )-transporter FOC08_03095 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC08_03110 ENOG4107ZXI Rhomboid family FOC08_03120 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC08_03125 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC08_03135 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC08_03235 ENOG4105K8N protein family UPF0079, ATPase FOC08_03240 ENOG41072GX Peptidase M22 Glycoprotease FOC08_03245 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC08_03250 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC08_03255 ENOG4105C5H ABC transporter FOC08_03270 ENOG4108TYN CAAX amino terminal protease family protein FOC08_03290 ENOG4105C7N Xanthine uracil vitamin C permease FOC08_03300 ENOG4105BZU Histidine kinase FOC08_03330 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC08_03370 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC08_03390 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_03410 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC08_03415 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC08_03420 ENOG4105C83 adenylosuccinate lyase FOC08_03430 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC08_03455 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC08_03465 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC08_03490 ENOG4105C4R Atp-dependent dna helicase FOC08_03515 ENOG4108W2Y isochorismatase FOC08_03520 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC08_03525 ENOG4108UMI ABC transporter, permease FOC08_03530 ENOG4105D01 (LipO)protein FOC08_03550 ENOG410834F Transcriptional regulator FOC08_03575 ENOG4105CBD Diacylglycerol kinase FOC08_03580 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC08_03585 ENOG4108JPW Aminotransferase FOC08_03595 ENOG4105C26 Dehydrogenase FOC08_03600 ENOG4105KPY Small multidrug resistance protein FOC08_03620 ENOG4105D9N nucleoside FOC08_03625 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC08_03640 ENOG4108W15 Protein of unknown function (DUF1456) FOC08_03655 ENOG4105DTQ mandelate racemase muconate lactonizing FOC08_03665 ENOG4105DFD Na H antiporter FOC08_03685 ENOG4105D3R alkyl hydroperoxide reductase FOC08_03690 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) FOC08_03700 ENOG4107W7X Aldolase FOC08_03705 ENOG4105EHG Permease protein FOC08_03710 ENOG4105DQ5 transport system permease protein FOC08_03715 ENOG4108V5C ABC transporter FOC08_03735 ENOG4106UIA FOC08_03740 ENOG4106UIA FOC08_03765 ENOG4105BZU Histidine kinase FOC08_03785 ENOG410756H nucleotidyltransferase FOC08_03790 ENOG4105D2S major facilitator superfamily FOC08_03805 ENOG4105E5Q amino acid AbC transporter FOC08_03810 ENOG4105EAB amino acid AbC transporter FOC08_03820 ENOG4105C8Q Methyl-accepting chemotaxis FOC08_03825 ENOG4105C8Q Methyl-accepting chemotaxis FOC08_03835 ENOG4105CI1 PTS System FOC08_03865 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC08_03880 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC08_03895 ENOG4105C5H ABC transporter FOC08_03920 ENOG41062JF Transcriptional regulator FOC08_03940 ENOG4105DEU major facilitator superfamily FOC08_03955 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) FOC08_03970 ENOG4108N0M stress protein FOC08_03975 ENOG4106FN3 tellurium resistance protein FOC08_03980 ENOG4106FN3 tellurium resistance protein FOC08_03985 ENOG4107TS3 membrane protein, TerC FOC08_03990 ENOG4108TTB tellurium resistance protein FOC08_04010 ENOG4105KJF protein tyrosine phosphatase FOC08_04020 ENOG4107U9T Pfam:Ribonuclease_BN FOC08_04025 ENOG4105C59 p-type ATPase FOC08_04030 ENOG4108IPJ Membrane FOC08_04050 ENOG4107ZTW SNARE associated Golgi FOC08_04065 ENOG410606W general stress protein FOC08_04070 ENOG4105UPD Calcium Proton FOC08_04110 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC08_04115 ENOG4105VTR Integrase FOC08_04120 ENOG4108IMY Transcriptional regulator FOC08_04380 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FOC08_04390 ENOG4108JUB Transcriptional regulator FOC08_04400 ENOG4108IQI permease FOC08_04425 ENOG4105CSV Glutaminase FOC08_04435 ENOG4108A04 Beta-lactamase FOC08_04450 ENOG4105CKK Glycosyl transferase, family 2 FOC08_04460 ENOG4107QQG Dehydrogenase FOC08_04465 ENOG4105C3I Nad-dependent epimerase dehydratase FOC08_04485 ENOG4105F1A Pyruvate formate-lyase FOC08_04505 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC08_04510 ENOG4105ECP epimerase FOC08_04540 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC08_04545 ENOG4105CEN a g-specific adenine glycosylase FOC08_04550 ENOG4106BXE FOC08_04570 ENOG4105BZ1 (ABC) transporter FOC08_04575 ENOG4107NBY Membrane FOC08_04580 ENOG4105CBC glutamate synthase FOC08_04590 ENOG4108IUW ABC transporter FOC08_04610 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC08_04615 ENOG4105G5W regulator Fur family FOC08_04730 ENOG4108JQC penicillin-binding protein 1A FOC08_04735 ENOG4107ZQN disulfide bond FOC08_04745 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC08_04755 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC08_04760 ENOG4105BZU Histidine kinase FOC08_04765 ENOG4105CYN Serine protein kinase FOC08_04785 ENOG4105C94 Transporter FOC08_04800 ENOG4105DZ6 Band 7 protein FOC08_04810 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC08_04820 ENOG4105D4T Citrate transporter FOC08_04840 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC08_04845 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC08_04850 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC08_04855 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC08_04860 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC08_04865 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC08_04870 ENOG4108STX response regulator FOC08_04875 ENOG4105US7 Histidine kinase FOC08_04900 ENOG4108MRH transcriptional regulatory protein FOC08_04910 ENOG4105C6K Malic enzyme FOC08_04920 ENOG4108UZ3 Transporter FOC08_04925 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC08_04935 ENOG4105BZU Histidine kinase FOC08_04940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_04945 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC08_04950 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC08_04955 ENOG4108JB9 formate dehydrogenase FOC08_04975 ENOG4105CUB amino acid FOC08_04985 ENOG4105C59 p-type ATPase FOC08_04990 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC08_05025 ENOG41073R8 VanW family FOC08_05030 ENOG4108KGH TRANSCRIPTIONal FOC08_05035 ENOG4105D9N nucleoside FOC08_05040 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC08_05045 ENOG4105C37 (CBS) domain FOC08_05050 ENOG4108IJ0 Aspartate ammonia-lyase FOC08_05055 ENOG4105DAA L-lactate FOC08_05070 ENOG4105DUX Transporter FOC08_05075 ENOG4108MES Periplasmic binding protein FOC08_05080 ENOG4105DQ5 transport system permease protein FOC08_05085 ENOG4108IHU transport system permease protein FOC08_05090 ENOG4105E0A ABC, transporter FOC08_05095 ENOG4105DMQ Methyltransferase FOC08_05105 ENOG4105EXW epimerase dehydratase FOC08_05115 ENOG4107T89 von Willebrand factor, type A FOC08_05120 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC08_05125 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC08_05140 ENOG4105BZU Histidine kinase FOC08_05145 ENOG4105D5Q Arginine ornithine antiporter FOC08_05150 ENOG4107414 GntR family transcriptional regulator FOC08_05155 ENOG4105C5Y PTS System FOC08_05160 ENOG4105CG3 alpha amylase, catalytic region FOC08_05175 ENOG4105E1K spore germination protein FOC08_05185 ENOG4105CRN Aminoglycoside phosphotransferase FOC08_05190 ENOG4105BZG amino acid carrier protein FOC08_05195 ENOG4105CDA abc transporter atp-binding protein FOC08_05200 ENOG4105CT1 (ABC) transporter FOC08_05205 ENOG4105EAD ABC transporter FOC08_05210 ENOG4105DRP amino acid AbC transporter FOC08_05215 ENOG4108IQI permease FOC08_05240 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC08_05245 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC08_05250 ENOG4105BZU Histidine kinase FOC08_05265 ENOG4105CHH sulfate transporter FOC08_05270 ENOG41068KF Universal stress protein FOC08_05280 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC08_05290 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC08_05295 ENOG4108JQ7 (ABC) transporter FOC08_05305 ENOG4105CXY transporter FOC08_05310 ENOG41067TZ transcriptional regulator, MarR family FOC08_05320 ENOG4105ETE Transcriptional regulator (LacI family FOC08_05325 ENOG4108RVA ribokinase FOC08_05335 ENOG4105C2J ABC transporter FOC08_05340 ENOG4105CNN ABC, transporter FOC08_05345 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC08_05350 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC08_05410 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC08_05415 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC08_05420 ENOG41069ER domain protein FOC08_05425 ENOG4105VZ8 Transcriptional regulator FOC08_05430 ENOG4107D63 FOC08_05440 ENOG4105DUX Transporter FOC08_05460 ENOG4105C85 amino acid FOC08_05465 ENOG4105C7N Xanthine uracil vitamin C permease FOC08_05505 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC08_05510 ENOG4105E2S oxidase) subunit II FOC08_05515 ENOG4108IQI permease FOC08_05530 ENOG4106CAD Protein of unknown function (DUF3311) FOC08_05535 ENOG4105E1V na solute symporter FOC08_05550 ENOG4108NHD germination protein FOC08_05555 ENOG4105CE1 Ferrous iron transport protein b FOC08_05560 ENOG4105CE1 Ferrous iron transport protein b FOC08_05565 ENOG4105CE1 Ferrous iron transport protein b FOC08_05570 ENOG4105CVA phosphate FOC08_05575 ENOG4105C8U phosphate abc transporter FOC08_05580 ENOG4105E2Z phosphate ABC transporter (Permease FOC08_05705 ENOG41080XQ Signal transduction protein with cbs domains FOC08_05725 ENOG4105ETU transcriptional activator (TenA FOC08_05735 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC08_05745 ENOG4108VEU Thiamine monophosphate synthase FOC08_05750 ENOG41080HI glycine oxidase FOC08_05765 ENOG4105D06 uba thif-type nad fad binding protein FOC08_05770 ENOG4105DWF phosphomethylpyrimidine kinase FOC08_05820 ENOG4108INS Transcriptional regulator FOC08_05835 ENOG4105C7N Xanthine uracil vitamin C permease FOC08_05865 ENOG4105C5Y PTS System FOC08_05920 ENOG4107Y03 Nitroreductase FOC08_05925 ENOG4105ED1 spovr family FOC08_05950 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC08_05955 ENOG4105XTG Pfam:DUF156 FOC08_05960 ENOG4105VFE sira family FOC08_05965 ENOG4107TPS domain protein FOC08_05970 ENOG4105VFE sira family FOC08_05975 ENOG41085GJ domain protein FOC08_05985 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC08_05990 ENOG41087NI Sulfite exporter TauE/SafE FOC08_06000 ENOG4108KGH TRANSCRIPTIONal FOC08_06025 ENOG4105EMD TRANSCRIPTIONal FOC08_06030 ENOG4105VCP PTS System FOC08_06035 ENOG4105VZJ PTS System FOC08_06055 ENOG41069ER domain protein FOC08_06060 ENOG4107RBB ABC transporter, permease FOC08_06065 ENOG4105C19 ABC transporter FOC08_06095 ENOG4105WEF catalase FOC08_06130 ENOG4107T5V SNARE associated Golgi FOC08_06160 ENOG4105CUB amino acid FOC08_06165 ENOG4107RWR Sodium hydrogen exchanger FOC08_06175 ENOG4106KNT transcriptional regulator FOC08_06210 ENOG4108PCN EamA-like transporter family FOC08_06215 ENOG4108YXU transcriptional regulator AsnC family FOC08_06225 ENOG4105KPY Small multidrug resistance protein FOC08_06230 ENOG4105KPY Small multidrug resistance protein FOC08_06255 ENOG4105NF4 modulator of drug activity FOC08_06260 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC08_06265 ENOG4105E5W Transporter FOC08_06275 ENOG4107RKG DJ-1/PfpI family FOC08_06280 ENOG4105CH6 catalase FOC08_06290 ENOG4105D5Q Arginine ornithine antiporter FOC08_06295 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC08_06305 ENOG4105C26 Dehydrogenase FOC08_06310 ENOG4105BZ1 (ABC) transporter FOC08_06325 ENOG4105DRP amino acid AbC transporter FOC08_06330 ENOG4105CDA abc transporter atp-binding protein FOC08_06345 ENOG410839P FOC08_06380 ENOG4107FQX Alpha-acetolactate decarboxylase FOC08_06410 ENOG4105D4P Coproporphyrinogen iii oxidase FOC08_06425 ENOG4105CHH sulfate transporter FOC08_06465 ENOG4106AKK s-layer domain-containing protein FOC08_06475 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC08_06480 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC08_06495 ENOG4105CGU Enoyl-CoA hydratase FOC08_06515 ENOG4105DER m42 family FOC08_06535 ENOG4105CTU Proline racemase FOC08_06575 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC08_06585 ENOG4108JQ7 (ABC) transporter FOC08_06590 ENOG4105PKS Excinuclease abc c subunit domain protein FOC08_06620 ENOG4105CSH Transporter FOC08_06630 ENOG4108MRH transcriptional regulatory protein FOC08_06680 ENOG4105CDU Replicative dna helicase FOC08_06710 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC08_06755 ENOG4107P5I polyketide synthase FOC08_06760 ENOG4108IG5 Transcriptional regulator FOC08_06780 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC08_06800 ENOG4105CMT Dihydroxyacetone kinase FOC08_06810 ENOG4105CMT Dihydroxyacetone kinase FOC08_06815 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FOC08_06820 ENOG410847I Transcriptional regulator, BadM Rrf2 family FOC08_06850 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC08_06915 ENOG4105WN5 stage II sporulation protein FOC08_06925 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_06935 ENOG4108MJI response regulator FOC08_06940 ENOG4105BZU Histidine kinase FOC08_06945 ENOG4105BZU Histidine kinase FOC08_06965 ENOG4105K8R UPF0145 protein FOC08_06995 ENOG4107VRP DNA repair exonuclease FOC08_07005 ENOG4105D7V transposase FOC08_07020 ENOG4108IND Tetr family transcriptional regulator FOC08_07025 ENOG4105EQ0 Major Facilitator superfamily FOC08_07045 ENOG4108MUZ hydrolase FOC08_07065 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC08_07080 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC08_07090 ENOG4105EMN RNA polymerase sigma factor FOC08_07115 ENOG4105C57 major facilitator superfamily FOC08_07120 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC08_07130 ENOG4105EEM helicase FOC08_07135 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC08_07160 ENOG4105K59 histidine triad (HIT) protein FOC08_07190 ENOG410905X membrane-flanked domain protein FOC08_07235 ENOG410905X membrane-flanked domain protein FOC08_07240 ENOG4105CKV Membrane FOC08_07245 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC08_07250 ENOG4105BZ4 penicillin-binding protein FOC08_07255 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FOC08_07265 ENOG4105C1Q protoporphyrinogen oxidase FOC08_07290 ENOG4105NA0 Transcriptional regulator FOC08_07305 ENOG4105ECB domain protein FOC08_07335 ENOG4106AXD FOC08_07340 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC08_07345 ENOG4105DF9 Lipoate-protein, ligase FOC08_07355 ENOG4105CEY Amp-dependent synthetase and ligase FOC08_07385 ENOG4105CNA YD repeat protein FOC08_07420 ENOG4107TVP HD domain protein FOC08_07430 ENOG4108AEY RNA polymerase sigma factor FOC08_07435 ENOG41086D8 Transcriptional regulator FOC08_07450 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_07475 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC08_07480 ENOG4105C8Q Methyl-accepting chemotaxis FOC08_07500 ENOG4105ZU5 s-layer protein FOC08_07505 ENOG4107QP3 malate synthase g FOC08_07520 ENOG4105VEQ Cold shock protein FOC08_07535 ENOG4105XVF Competence transcription factor FOC08_07550 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination FOC08_07555 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FOC08_07600 ENOG4105ERH Fumarylacetoacetate hydrolase FOC08_07625 ENOG4105CAQ asparagine synthetase FOC08_07630 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC08_07635 ENOG4105CH6 catalase FOC08_07660 ENOG4105QNR S1 RNA binding domain protein FOC08_07670 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC08_07680 ENOG4107AYK membrAne FOC08_07685 ENOG41073B9 FOC08_07695 ENOG4108KP7 hydrolase FOC08_07705 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC08_07730 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC08_07735 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC08_07750 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC08_07765 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC08_07770 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC08_07780 ENOG4108JQ7 (ABC) transporter FOC08_07785 ENOG4105UQX Mate efflux family protein FOC08_07805 ENOG4108ZCF integral membrane protein FOC08_07815 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC08_07825 ENOG4105DPN Oligoendopeptidase f FOC08_07835 ENOG4108Z18 K06886 hemoglobin FOC08_07840 ENOG4105MIX Adenylate cyclase FOC08_07855 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FOC08_07860 ENOG4105EMS pseudouridine synthase FOC08_07880 ENOG4105K64 Glycosyl transferase, family 2 FOC08_07900 ENOG4107TVC Glycosyl transferase, family 2 FOC08_07920 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC08_07925 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC08_07935 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC08_07985 ENOG4108WVJ 2'-5' rna ligase FOC08_08010 ENOG4105CK7 Sodium proline symporter FOC08_08015 ENOG4105CRQ synthase (Component I) FOC08_08020 ENOG4105DDQ anthranilate synthase FOC08_08115 ENOG4105C7S Dehydrogenase FOC08_08125 ENOG4105VZ8 Transcriptional regulator FOC08_08185 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FOC08_08195 ENOG4105DZ1 carboxypeptidase FOC08_08200 ENOG4105VFR signal peptidase FOC08_08235 ENOG4105C26 Dehydrogenase FOC08_08240 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC08_08245 ENOG4105F38 ABC transporter, permease FOC08_08250 ENOG4105D38 putrescine abc transporter FOC08_08255 ENOG4107RUE extracellular solute-binding protein family 1 FOC08_08265 ENOG4105EYF MMPL domain protein FOC08_08275 ENOG4108YBP pseudouridine synthase FOC08_08285 ENOG4105K4I Scp-like extracellular FOC08_08290 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC08_08295 ENOG4105CQB FAD linked oxidase domain protein FOC08_08310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_08315 ENOG4105BZU Histidine kinase FOC08_08320 ENOG4105JXH GntR family transcriptional regulator FOC08_08340 ENOG4106A3R peptidase FOC08_08350 ENOG4108QTI )-transporter FOC08_08355 ENOG4107TS3 membrane protein, TerC FOC08_08360 ENOG4105CZN Potassium uptake protein FOC08_08365 ENOG410681C small acid-soluble spore protein FOC08_08370 ENOG4108Z7G MaoC domain protein dehydratase FOC08_08390 ENOG4105CHR reductase FOC08_08400 ENOG4105MWK D-amino acid dehydrogenase, small subunit FOC08_08415 ENOG4105C4Y ABC transporter FOC08_08430 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FOC08_08445 ENOG4105E98 transcriptional regulator DeoR family FOC08_08465 ENOG4105PXI polysaccharide deacetylase FOC08_08475 ENOG4105BZU Histidine kinase FOC08_08480 ENOG41090MY MarR family Transcriptional regulator FOC08_08490 ENOG4106DF1 FOC08_08495 ENOG4105BZU Histidine kinase FOC08_08505 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC08_08510 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC08_08545 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC08_08565 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC08_08570 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC08_08575 ENOG4105CZV ABC transporter FOC08_08585 ENOG4105CJ1 ABC, transporter FOC08_08625 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC08_08630 ENOG4105EA8 2-Nitropropane dioxygenase FOC08_08635 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC08_08645 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC08_08665 ENOG4105NQC Flavodoxin FOC08_08690 ENOG4107QMU Mate efflux family protein FOC08_08695 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC08_08725 ENOG4105CZN Potassium uptake protein FOC08_08730 ENOG41063Y9 FOC08_08735 ENOG4105KBJ sporulation protein ytfj FOC08_08760 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC08_08765 ENOG4105C7K acetolactate synthase FOC08_08770 ENOG4108ZP8 Acetolactate synthase small subunit FOC08_08775 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC08_08785 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FOC08_08810 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FOC08_08845 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC08_08860 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC08_08865 ENOG4105E0M Sulfatase FOC08_08875 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC08_08895 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC08_08900 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC08_08910 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC08_08915 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC08_08920 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC08_08925 ENOG4105C8J )-transporter FOC08_08945 ENOG4105DFD Na H antiporter FOC08_08965 ENOG4105ENE Histidine kinase FOC08_08970 ENOG4105WH1 Two component transcriptional regulator luxr family FOC08_08990 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FOC08_09015 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FOC08_09035 ENOG4105CJ3 phosphate transporter FOC08_09040 ENOG4107GRR phosphate transport regulator FOC08_09045 ENOG4105BZ4 penicillin-binding protein FOC08_09065 ENOG4105I3N Conserved Protein FOC08_09080 ENOG4105BZU Histidine kinase FOC08_09115 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC08_09120 ENOG4105DZ1 carboxypeptidase FOC08_09125 ENOG4108JIC nucleoside recognition domain protein FOC08_09135 ENOG4105FE9 pseudouridine synthase FOC08_09145 ENOG4107TWT Cytochrome c biogenesis protein FOC08_09150 ENOG4105CRE cytochrome C FOC08_09155 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_09160 ENOG4105BZU Histidine kinase FOC08_09165 ENOG4108WBT adenosyltransferase FOC08_09180 ENOG4108SAX Membrane FOC08_09190 ENOG4105T7X FOC08_09195 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC08_09200 ENOG4105I7S Abortive infection protein FOC08_09215 ENOG4107X2D transcriptional regulator, merr family FOC08_09220 ENOG4108S6Z Negative regulator of genetic competence FOC08_09245 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC08_09250 ENOG4105HDK L-asparaginase FOC08_09285 ENOG4105S2F FOC08_09290 ENOG41065D1 FOC08_09320 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC08_09335 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC08_09345 ENOG4105EAH synthase FOC08_09365 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC08_09370 ENOG41068YB TPR repeat-containing protein FOC08_09385 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC08_09390 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC08_09395 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit FOC08_09425 ENOG4108JYZ YitT family FOC08_09430 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC08_09445 ENOG4105FJR Lmbe family FOC08_09450 ENOG4105CPK Glycosyl transferase (Group 1 FOC08_09485 ENOG4105DVT helicase FOC08_09490 ENOG4105YAC FOC08_09510 ENOG4105CSM endonuclease III FOC08_09520 ENOG4105BZ4 penicillin-binding protein FOC08_09575 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC08_09585 ENOG4105DVT helicase FOC08_09590 ENOG4105CTD carboxy-peptidase FOC08_09605 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC08_09620 ENOG4105C2W permease FOC08_09625 ENOG4105DHF Membrane FOC08_09635 ENOG410890F Dynamin family FOC08_09645 ENOG4108W0I acetyltransferase FOC08_09655 ENOG4105KHC sulfurtransferase FOC08_09755 ENOG4108SZE gCN5-related N-acetyltransferase FOC08_09775 ENOG41081VK Ribonuclease FOC08_09840 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC08_09850 ENOG4107RWR Sodium hydrogen exchanger FOC08_09860 ENOG4108Z5V transcriptional regulator, merr family FOC08_09870 ENOG4105H67 Protein of unknown function (DUF421) FOC08_09875 ENOG41080C8 DUF218 domain FOC08_09930 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC08_09940 ENOG4107R0U MotA TolQ exbB proton channel FOC08_09945 ENOG4105ER2 Ompa motb domain protein FOC08_09950 ENOG4107YTP response regulator receiver protein FOC08_09960 ENOG4105DD5 Flagellar motor switch protein FOC08_09975 ENOG4105BZU Histidine kinase FOC08_09995 ENOG4105E1Q flagellar hook-associated protein FOC08_10020 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC08_10025 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC08_10030 ENOG41075Z6 flagellar hook-basal body complex protein fliE FOC08_10040 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC08_10075 ENOG4105BZE flagellar hook protein, FlgE FOC08_10100 ENOG4105K64 Glycosyl transferase, family 2 FOC08_10135 ENOG4105I03 Flagellin FOC08_10140 ENOG4105E4C Lytic transglycosylase catalytic FOC08_10155 ENOG4105DD5 Flagellar motor switch protein FOC08_10165 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC08_10170 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC08_10180 ENOG4105D00 flagellar biosynthetic protein flhB FOC08_10185 ENOG4105D7B Flagellar biosynthesis protein flha FOC08_10195 ENOG4105KTQ flagellar basal-body rod protein FOC08_10200 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC08_10225 ENOG4108RZE Tetr family transcriptional regulator FOC08_10245 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC08_10270 ENOG4105DUM transcriptional regulator, lysR family FOC08_10275 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC08_10280 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC08_10285 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC08_10290 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC08_10330 ENOG4105CVJ phosphoglycerate mutase FOC08_10360 ENOG4105CAQ asparagine synthetase FOC08_10380 ENOG4105PGM cation diffusion facilitator family transporter FOC08_10390 ENOG4105DRR Transcriptional regulator, GntR family FOC08_10395 ENOG4108UZ3 Transporter FOC08_10400 ENOG4105CKI cobalamin synthesis protein FOC08_10405 ENOG4108PJD permease FOC08_10420 ENOG4105DFD Na H antiporter FOC08_10425 ENOG4105C9Q fumarate hydratase class II FOC08_10450 ENOG4105EC3 peptidase S51, dipeptidase E FOC08_10470 ENOG4107QIV Cytochrome c biogenesis protein FOC08_10500 ENOG4106BRA Membrane FOC08_10535 ENOG4105CJ1 ABC, transporter FOC08_10555 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC08_10565 ENOG4108IJ0 Aspartate ammonia-lyase FOC08_10570 ENOG4105C6K Malic enzyme FOC08_10630 ENOG4105FVX FOC08_10670 ENOG4105CSR polyphosphate kinase 2 FOC08_10690 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC08_10700 ENOG4105EU0 Major facilitator Superfamily FOC08_10705 ENOG4105C6T cysteine synthase FOC08_10725 ENOG4105C8J )-transporter FOC08_10735 ENOG4105X5K response regulator receiver protein FOC08_10740 ENOG4105H67 Protein of unknown function (DUF421) FOC08_10755 ENOG4106KE4 Dehydrogenase FOC08_10770 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC08_10775 ENOG4105CHR reductase FOC08_10780 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC08_10785 ENOG4105C7K acetolactate synthase FOC08_10790 ENOG4108ZP8 Acetolactate synthase small subunit FOC08_10795 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC08_10805 ENOG4105C7B Threonine dehydratase FOC08_10830 ENOG4105C6X Major Facilitator FOC08_10835 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC08_10845 ENOG4105DY9 regulatoR FOC08_10850 ENOG4105CYC Transferase FOC08_10870 ENOG4105F6J Alpha beta hydrolase fold FOC08_10905 ENOG41068WN FOC08_10925 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC08_10930 ENOG4105C72 UPF0176 protein FOC08_10940 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOC08_10970 ENOG4107RHR regulatoR FOC08_10980 ENOG4105D9N nucleoside FOC08_10985 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC08_11020 ENOG4107RAQ aminopeptidase FOC08_11025 ENOG4107STQ Multicopper oxidase FOC08_11070 ENOG4108T5E Copper resistance protein FOC08_11075 ENOG4105KTB nuclear export factor GLE1 FOC08_11085 ENOG4107RT3 EamA-like transporter family FOC08_11090 ENOG4105GZI Transcriptional regulator FOC08_11095 ENOG4108Z40 Transcriptional regulator FOC08_11100 ENOG4107ZXU DSBA oxidoreductase FOC08_11105 ENOG4108TVJ Nitroreductase FOC08_11110 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC08_11115 ENOG4106F5Q Membrane FOC08_11120 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC08_11130 ENOG4105CKI cobalamin synthesis protein FOC08_11150 ENOG4108Z7G MaoC domain protein dehydratase FOC08_11155 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC08_11165 ENOG4105C0Z ABC transporter FOC08_11170 ENOG4108IV0 ABC, transporter FOC08_11175 ENOG4105C32 Amino acid ABC transporter (Permease) FOC08_11185 ENOG4105SKE transcriptional Regulator LysR family FOC08_11205 ENOG4105YGB Transcriptional regulator FOC08_11215 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC08_11220 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC08_11225 ENOG4108JJ9 ABC, transporter FOC08_11230 ENOG4108JJ8 (ABC) transporter FOC08_11280 ENOG4105EFI regulatoR FOC08_11285 ENOG4105BZU Histidine kinase FOC08_11305 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC08_11310 ENOG4108ZJ4 polysaccharide deacetylase FOC08_11330 ENOG4105D6E homoserine dehydrogenase FOC08_11355 ENOG4108KGH TRANSCRIPTIONal FOC08_11365 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_11370 ENOG4105BZU Histidine kinase FOC08_11375 ENOG4107VMI polysaccharide deacetylase FOC08_11385 ENOG4105KT7 mgtC SapB transporter FOC08_11390 ENOG4105VRR gCN5-related N-acetyltransferase FOC08_11400 ENOG4105DUU IucA IucC family protein FOC08_11405 ENOG4105CEY Amp-dependent synthetase and ligase FOC08_11420 ENOG4108WBH protein TIM barrel FOC08_11425 ENOG4105YWU small acid-soluble spore protein FOC08_11435 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC08_11485 ENOG4105KRN Transcriptional regulator, abrb family FOC08_11495 ENOG4105YVS arsR family transcriptional regulator FOC08_11500 ENOG4107SET aldo keto reductase FOC08_11505 ENOG4107XZQ multidrug resistance protein FOC08_11530 ENOG4105C8Q Methyl-accepting chemotaxis FOC08_11545 ENOG4108K88 Membrane FOC08_11550 ENOG4108WPJ Ferritin-like domain FOC08_11565 ENOG4105DEN Luciferase family FOC08_11585 ENOG4107QM2 Aldo Keto reductase FOC08_11590 ENOG4105CKI cobalamin synthesis protein FOC08_11645 ENOG4105DSE periplasmic solute binding protein FOC08_11650 ENOG4105K4T epimerase FOC08_11660 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC08_11685 ENOG4105CVJ phosphoglycerate mutase FOC08_11705 ENOG4107T5V SNARE associated Golgi FOC08_11720 ENOG4108PJD permease FOC08_11730 ENOG4108S4H thioesterase Superfamily protein FOC08_11740 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC08_11760 ENOG4105SXS Protein of unknown function (DUF456) FOC08_11765 ENOG4105C37 (CBS) domain FOC08_11785 ENOG4108Z7R Chaperone CsaA FOC08_11805 ENOG4108ZRV stage ii sporulation protein p FOC08_11815 ENOG4108VXD carboxy-peptidase FOC08_11825 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC08_11850 ENOG4108X4Q Hydrolase FOC08_11860 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC08_11865 ENOG4107RBS Methyltransferase FOC08_11880 ENOG41087PP glycosyltransferase MGT family FOC08_11885 ENOG4108JYZ YitT family FOC08_11890 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC08_11915 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC08_11965 ENOG4105KBJ sporulation protein ytfj FOC08_11990 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC08_12015 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_12025 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC08_12030 ENOG4105EMN RNA polymerase sigma factor FOC08_12055 ENOG4108V06 Glutathione peroxidase FOC08_12070 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC08_12090 ENOG4108IUE nitrate reductase beta subunit FOC08_12095 ENOG4105R3A Nitrate reductase FOC08_12120 ENOG4107V6Q Cyclic nucleotide-binding domain FOC08_12125 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC08_12130 ENOG4105D06 uba thif-type nad fad binding protein FOC08_12135 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC08_12140 ENOG4108ZAF Molybdopterin FOC08_12165 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC08_12170 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC08_12175 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC08_12180 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC08_12185 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC08_12190 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC08_12225 ENOG4105MCT stage V sporulation protein S FOC08_12240 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC08_12260 ENOG4105C5H ABC transporter FOC08_12275 ENOG4108UUM single-stranded DNA-binding protein FOC08_12305 ENOG4107YX5 Pfam:DUF548 FOC08_12310 ENOG4105C75 arginyL-tRNA synthetase FOC08_12335 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FOC08_12355 ENOG4105C5S asparaginyl-tRNA synthetase FOC08_12375 ENOG4105EC2 ftsk spoIIIe FOC08_12445 ENOG4105BZW Glycerate kinase FOC08_12450 ENOG4107QPK )-transporter FOC08_12455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_12460 ENOG41062D9 Histidine kinase FOC08_12475 ENOG4105C8J )-transporter FOC08_12495 ENOG4107XGZ Hydrolase FOC08_12500 ENOG4105CY2 Citrate transporter FOC08_12505 ENOG4105C0A alcohol dehydrogenase FOC08_12520 ENOG4105KD7 acetyltransferase FOC08_12550 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC08_12570 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC08_12585 ENOG4107RVG penicillin-binding protein FOC08_12590 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FOC08_12595 ENOG4105E9Q Acyl-transferase FOC08_12600 ENOG4108UT2 hemolysin iii FOC08_12610 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC08_12620 ENOG4108RCR degv family FOC08_12625 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC08_12630 ENOG4108KF3 Electron transport protein SCO1 SenC FOC08_12635 ENOG4107Y70 Heat shock protein FOC08_12640 ENOG4105CAQ asparagine synthetase FOC08_12655 ENOG4108MES Periplasmic binding protein FOC08_12660 ENOG4105F0I Aminotransferase FOC08_12695 ENOG4105D8X mechanosensitive ion channel FOC08_12700 ENOG4105BZU Histidine kinase FOC08_12705 ENOG4105WH1 Two component transcriptional regulator luxr family FOC08_12740 ENOG4105CMG Carbohydrate kinase FOC08_12745 ENOG4105CMG Carbohydrate kinase FOC08_12775 ENOG4108IJ8 ABC transporter FOC08_12780 ENOG4105E90 ABC transporter FOC08_12815 ENOG4105C37 (CBS) domain FOC08_12840 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC08_12855 ENOG4107S4Y M20 DapE family protein YgeY FOC08_12860 ENOG4108TSC N-acetyltransferase FOC08_12865 ENOG4108JUB Transcriptional regulator FOC08_12870 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC08_12910 ENOG4108N23 SpoOM-related protein FOC08_12915 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC08_12925 ENOG4105SZ6 Thioredoxin FOC08_12940 ENOG4108IBT Inherit from COG: transposase FOC08_13045 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC08_13085 ENOG4105BZ4 penicillin-binding protein FOC08_13090 ENOG4105CZM Major Facilitator FOC08_13095 ENOG4105W8X HesB YadR YfhF-family protein FOC08_13105 ENOG4105DXD 2-methylcitrate dehydratase FOC08_13110 ENOG4105CR4 methylisocitrate lyase FOC08_13115 ENOG4105C1G acyl-Coa dehydrogenase FOC08_13120 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC08_13130 ENOG4105N14 lysine exporter protein LysE YggA FOC08_13135 ENOG4105E39 Enoyl-CoA hydratase FOC08_13150 ENOG4107RFY SbcCD D subunit FOC08_13155 ENOG4105EYH Exonuclease FOC08_13175 ENOG4105FCD Major Facilitator FOC08_13180 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC08_13185 ENOG4105E4F Isochorismate synthase FOC08_13190 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC08_13195 ENOG4105WQI isochorismatase FOC08_13200 ENOG4105CEY Amp-dependent synthetase and ligase FOC08_13205 ENOG4105WQT MbtH domain protein FOC08_13210 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC08_13225 ENOG4105K70 DNA-binding protein FOC08_13245 ENOG4105BZG amino acid carrier protein FOC08_13265 ENOG4105FE9 pseudouridine synthase FOC08_13270 ENOG4105C22 threonyL-tRNA synthetase FOC08_13285 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC08_13310 ENOG4108D32 Methyltransferase FOC08_13340 ENOG41081I9 integral membrane protein FOC08_13355 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC08_13365 ENOG4105EYF MMPL domain protein FOC08_13390 ENOG4105WCN acetyltransferase FOC08_13420 ENOG4105C1Q protoporphyrinogen oxidase FOC08_13430 ENOG41068WN FOC08_13440 ENOG4105VEQ Cold shock protein FOC08_13460 ENOG410667J hydrolase FOC08_13495 ENOG4107V2S Transcriptional regulator FOC08_13500 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC08_13515 ENOG4105DND Transcriptional regulator FOC08_13520 ENOG4108RPX mosc domain containing protein FOC08_13535 ENOG4105BZ1 (ABC) transporter FOC08_13540 ENOG4105BZ1 (ABC) transporter FOC08_13560 ENOG4108JCI Transcriptional regulator FOC08_13590 ENOG4108KPJ rna polymerase sigma factor FOC08_13640 ENOG4105RD7 BadF BadG BcrA BcrD FOC08_13650 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC08_13670 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC08_13685 ENOG4105C1J atp-dependent rna helicase FOC08_13700 ENOG4108RZE Tetr family transcriptional regulator FOC08_13720 ENOG41088CC tellurite resistance protein tehB FOC08_13730 ENOG4108I0C methyltransferase FOC08_13735 ENOG4107RA9 decarboxylase FOC08_13740 ENOG41090HR transcriptional regulator FOC08_13770 ENOG4105CIN aminoacyl-histidine dipeptidase FOC08_13795 ENOG4107RF6 penicillin-binding protein FOC08_13810 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC08_13815 ENOG4105ETE Transcriptional regulator (LacI family FOC08_13820 ENOG4105IE8 Alpha-ketoglutarate permease FOC08_13825 ENOG4105CK5 oxidoreductase FOC08_13850 ENOG4105D2N Aldolase FOC08_13855 ENOG4105DH8 myo-inositol catabolism FOC08_13885 ENOG4105VZ8 Transcriptional regulator FOC08_13900 ENOG4108VXD carboxy-peptidase FOC08_13920 ENOG41067SE Tetr family transcriptional regulator FOC08_13925 ENOG4105C5H ABC transporter FOC08_13935 ENOG4105BZU Histidine kinase FOC08_13950 ENOG4106ANW SMI1_KNR4 FOC08_13955 ENOG4105CEP NADH dehydrogenase FOC08_13960 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FOC08_13975 ENOG4105CJ1 ABC, transporter FOC08_13985 ENOG4107Z3H Transcriptional regulator, TetR family FOC08_14000 ENOG4105C1G acyl-Coa dehydrogenase FOC08_14005 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC08_14010 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC08_14015 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC08_14020 ENOG4105E39 Enoyl-CoA hydratase FOC08_14025 ENOG4107QX3 carboxylase FOC08_14030 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC08_14040 ENOG4105WCN acetyltransferase FOC08_14045 ENOG4105DBI uridine monophosphokinase FOC08_14060 ENOG4105DZ1 carboxypeptidase FOC08_14075 ENOG4105T9C HD domain FOC08_14085 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC08_14125 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC08_14125 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC08_14140 ENOG4105FQP Beta-lactamase FOC08_14150 ENOG4107Y80 Major Facilitator superfamily FOC08_14165 ENOG4105CUV Homoserine Kinase FOC08_14200 ENOG4105CPQ Dehydrogenase FOC08_14305 ENOG4105ETU transcriptional activator (TenA FOC08_14405 ENOG410667J hydrolase FOC08_14415 ENOG4105BZU Histidine kinase FOC08_14420 ENOG4107RF6 penicillin-binding protein FOC08_14440 ENOG4108JJB ABC transporter FOC08_14455 ENOG4108HGU Histidine kinase FOC08_14470 ENOG4105CB2 alcohol dehydrogenase FOC08_14475 ENOG4105CJN penicillin-binding protein FOC08_14485 ENOG4105FQP Beta-lactamase FOC08_14520 ENOG4108V4B ThiJ pfpI FOC08_14550 ENOG4107Y80 Major Facilitator superfamily FOC08_14565 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC08_14585 ENOG4107Y9U Membrane FOC08_14615 ENOG4105FCD Major Facilitator FOC08_14630 ENOG4105E09 nadh pyrophosphatase FOC08_14635 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC08_14640 ENOG4108Z4K mutator MutT protein FOC08_14675 ENOG4108XI2 Domain of unknown function (DUF1963) FOC08_14705 ENOG4105KWG Pfam:DUF1696 FOC08_14740 ENOG4105PKS Excinuclease abc c subunit domain protein FOC08_14780 ENOG4107VFR oxidoreductase FOC08_14805 ENOG4105PAD Hydrolase FOC08_14825 ENOG4105DY8 decarboxylase FOC08_14840 ENOG4108IUM Glycogen debranching enzyme FOC08_14865 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC08_14875 ENOG4105FDR Membrane FOC08_14910 ENOG4108V3A UPF0421 protein FOC08_14930 ENOG4105MSI germination protein ypeb FOC08_14950 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) FOC08_14955 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) FOC08_14960 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) FOC08_14965 ENOG4107Z3H Transcriptional regulator, TetR family FOC08_14995 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC08_15010 ENOG4105E98 transcriptional regulator DeoR family FOC08_15030 ENOG41062ES Transcriptional regulator FOC08_15050 ENOG4107QKR Dehydrogenase FOC08_15060 ENOG4107RUY (E1 component), alpha subunit FOC08_15070 ENOG4105E1F short-chain dehydrogenase reductase FOC08_15075 ENOG4105RHY Pfam:UPF0157 FOC08_15105 ENOG4107SQ8 Glycine betaine FOC08_15110 ENOG4108IJ7 Glycine betaine FOC08_15135 ENOG4105E66 phosphoriboisomerase A FOC08_15140 ENOG41082BV acetyltransferase FOC08_15145 ENOG4108M1A Chitin-binding protein FOC08_15180 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC08_15230 ENOG4105EEM helicase FOC08_15250 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC08_15295 ENOG4108M1A Chitin-binding protein FOC08_15315 ENOG4105BZG amino acid carrier protein FOC08_15320 ENOG4105C26 Dehydrogenase FOC08_15325 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC08_15330 ENOG4105CTU Proline racemase FOC08_15335 ENOG4105CTU Proline racemase FOC08_15340 ENOG41080HI glycine oxidase FOC08_15380 ENOG4107T5V SNARE associated Golgi FOC08_15395 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC08_15400 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FOC08_15415 ENOG4105DTQ mandelate racemase muconate lactonizing FOC08_15460 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC08_15465 ENOG4105BZU Histidine kinase FOC08_15505 ENOG4105DPN Oligoendopeptidase f FOC08_15520 ENOG4105EPR degv family FOC08_15560 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC08_15565 ENOG4106K7D Major facilitator family transporter FOC08_15585 ENOG4107BMA Transglycosylase associated protein FOC08_15600 ENOG41089UC methyltransferase, type 11 FOC08_15635 ENOG4105CHM Aminotransferase FOC08_15705 ENOG4105C02 permease FOC08_15715 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC08_15720 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC08_15725 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC08_15750 ENOG4105E09 nadh pyrophosphatase FOC08_15770 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC08_15820 ENOG4107VC0 DNA alkylation repair enzyme FOC08_15830 ENOG4107VMI polysaccharide deacetylase FOC08_15840 ENOG4108ZCF integral membrane protein FOC08_15845 ENOG4105E0M Sulfatase FOC08_15850 ENOG4105C5H ABC transporter FOC08_15860 ENOG4105EYF MMPL domain protein FOC08_15865 ENOG4105EYF MMPL domain protein FOC08_15870 ENOG4105EYF MMPL domain protein FOC08_15875 ENOG41082JN Transcriptional regulator FOC08_15895 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC08_15900 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FOC08_15905 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC08_15940 ENOG41069ER domain protein FOC08_15950 ENOG4105EMN RNA polymerase sigma factor FOC08_15975 ENOG4105D4B ABC, transporter FOC08_15985 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC08_15995 ENOG4105DKT Transcriptional regulator FOC08_16010 ENOG41061GT Aldolase FOC08_16030 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC08_16060 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FOC08_16065 ENOG4105II7 pyrroline-5-carboxylate reductase FOC08_16075 ENOG4107258 Transcriptional regulator FOC08_16085 ENOG4105E0Y RtcB Protein FOC08_16090 ENOG4105ECK Fatty Acid Desaturase FOC08_16095 ENOG4105G6Z alkaline phosphatase FOC08_16105 ENOG4105VMP Transcriptional regulator FOC08_16120 ENOG41090T1 Membrane FOC08_16130 ENOG4108WCX response regulator FOC08_16140 ENOG41068WN FOC08_16165 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC08_16190 ENOG4105CKK Glycosyl transferase, family 2 FOC08_16215 ENOG4105CKK Glycosyl transferase, family 2 FOC08_16225 ENOG4105C8Y Acetylornithine aminotransferase FOC08_16265 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC08_16275 ENOG4108TVJ Nitroreductase FOC08_16280 ENOG4105FS7 Transcriptional regulator FOC08_16315 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC08_16325 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC08_16355 ENOG4108XET gCN5-related N-acetyltransferase FOC08_16435 ENOG410635A Membrane FOC08_16440 ENOG4105KNA -acetyltransferase FOC08_16445 ENOG4108IQI permease FOC08_16455 ENOG4105F1N DNA alkylation repair FOC08_16500 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOC08_16535 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC08_16540 ENOG4107258 Transcriptional regulator FOC08_16550 ENOG4106N3A copper homeostasis protein cutc FOC08_16555 ENOG4108ZRV stage ii sporulation protein p FOC08_16560 ENOG4108ZHR arsR family transcriptional regulator FOC08_16570 ENOG4105FDT acyl-CoA dehydrogenase FOC08_16585 ENOG4105DWD nucleoside recognition domain protein FOC08_16615 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC08_16675 ENOG4105E2A Dehydrogenase FOC08_16690 ENOG4108IJ0 Aspartate ammonia-lyase FOC08_16695 ENOG4105HDK L-asparaginase FOC08_16700 ENOG4108IMY Transcriptional regulator FOC08_16710 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC08_16715 ENOG4105CUB amino acid FOC08_16725 ENOG4105II7 pyrroline-5-carboxylate reductase FOC08_16735 ENOG4105C6K Malic enzyme FOC08_16770 ENOG4105CSV Glutaminase FOC08_16805 ENOG4105CGH 5'-nucleotidase FOC08_16810 ENOG4105CH6 catalase FOC08_16820 ENOG4105CHJ isochorismatase hydrolase FOC08_16845 ENOG41090MY MarR family Transcriptional regulator FOC08_16880 ENOG4108606 TspO/MBR family FOC08_16885 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC08_16900 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC08_16905 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC08_16920 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC08_16925 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FOC08_16930 ENOG4105DSE periplasmic solute binding protein FOC08_16935 ENOG4105CC5 ABC transporter FOC08_16940 ENOG4105DIK (ABC) transporter FOC08_16970 ENOG4105D6J arsenicaL-resistance protein FOC08_16975 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_16980 ENOG41085FC arsR family transcriptional regulator FOC08_16995 ENOG4105F7F Chaperone FOC08_17005 ENOG4105CHR reductase FOC08_17010 ENOG4108YXU transcriptional regulator AsnC family FOC08_17085 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC08_17090 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC08_17100 ENOG4105IIP Membrane FOC08_17115 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_17120 ENOG41062D9 Histidine kinase FOC08_17145 ENOG4105K6H D-cysteine desulfhydrase FOC08_17165 ENOG4105VZ8 Transcriptional regulator FOC08_17180 ENOG4108NNI Beta-lactamase domain-containing protein FOC08_17185 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOC08_17195 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC08_17200 ENOG4105JQZ Methyltransferase FOC08_17215 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC08_17220 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC08_17235 ENOG4105BZU Histidine kinase FOC08_17250 ENOG4108U05 Transcriptional regulator FOC08_17265 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC08_17270 ENOG4105DJB Major Facilitator Superfamily FOC08_17275 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FOC08_17280 ENOG4107QR9 Iron-sulfur cluster binding protein FOC08_17290 ENOG4106P55 Transcriptional regulator FOC08_17300 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC08_17330 ENOG4105TRI Hydrolase FOC08_17360 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC08_17390 ENOG4107QJQ Mate efflux family protein FOC08_17410 ENOG4105EQ0 Major Facilitator superfamily FOC08_17415 ENOG4108JGH Tetr family transcriptional regulator FOC08_17430 ENOG4105C44 Serine transporter FOC08_17435 ENOG4105EJQ L-serine dehydratase FOC08_17450 ENOG4108JPW Aminotransferase FOC08_17465 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FOC08_17475 ENOG4105DVH amino acid FOC08_17490 ENOG4108JQ1 Dehydrogenase FOC08_17510 ENOG4108AEY RNA polymerase sigma factor FOC08_17525 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC08_17530 ENOG410874W AraC family transcriptional regulator FOC08_17580 ENOG4108ISG Major Facilitator FOC08_17590 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC08_17595 ENOG4105CZM Major Facilitator FOC08_17615 ENOG4105DA5 (ABC) transporter FOC08_17620 ENOG41069JR FOC08_17630 ENOG4105RXJ FOC08_17635 ENOG4105KPY Small multidrug resistance protein FOC08_17640 ENOG4105KBX Transcriptional regulator, TetR family FOC08_17650 ENOG4105CRW Short chain fatty acid transporter FOC08_17660 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC08_17690 ENOG4108JJB ABC transporter FOC08_17695 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC08_17720 ENOG4108K8S endonuclease I FOC08_17735 ENOG41067QW Transcriptional regulator FOC08_17745 ENOG4108Z66 YbaK ebsC protein FOC08_17750 ENOG4105CUT histidyl-tRNA synthetase FOC08_17765 ENOG4105KVH Transcriptional regulator FOC08_17770 ENOG4108RCM Nitroreductase FOC08_17790 ENOG4108PSK reductase FOC08_17800 ENOG4105CJ1 ABC, transporter FOC08_17860 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_17865 ENOG4105DKQ ROK family FOC08_17870 ENOG4106UW1 Major Facilitator superfamily FOC08_17875 ENOG4108UW5 maltose o-acetyltransferase FOC08_17885 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC08_17890 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC08_17895 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FOC08_17915 ENOG4105DMQ Methyltransferase FOC08_17925 ENOG4105EV4 Multidrug resistance protein mdtH FOC08_17955 ENOG4105C37 (CBS) domain FOC08_17970 ENOG4105DDN Pentapeptide repeat-containing protein FOC08_17975 ENOG4105XDF Protein of unknown function (DUF1272) FOC08_17980 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC08_17985 ENOG4105CMG Carbohydrate kinase FOC08_17990 ENOG4105C6Z Gluconate FOC08_17995 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC08_18010 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC08_18015 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC08_18020 ENOG4105CIS alcohol dehydrogenase FOC08_18025 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FOC08_18040 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FOC08_18045 ENOG4105D4Y metalloprotease FOC08_18065 ENOG4105CV8 reductase FOC08_18070 ENOG4105F27 Major Facilitator FOC08_18085 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) FOC08_18090 ENOG4105C44 Serine transporter FOC08_18120 ENOG4105KVH Transcriptional regulator FOC08_18125 ENOG4108TZY GntR Family Transcriptional Regulator FOC08_18135 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FOC08_18140 ENOG4105KVH Transcriptional regulator FOC08_18145 ENOG4105KVH Transcriptional regulator FOC08_18180 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC08_18190 ENOG4105CHR reductase FOC08_18210 ENOG4105KVH Transcriptional regulator FOC08_18280 ENOG4105KAF membrAne FOC08_18305 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC08_18320 ENOG4107YXZ hydrolase, family 25 FOC08_18345 ENOG4105ED2 Beta-lactamase FOC08_18355 ENOG4105H3G oxidoreductase FOC08_18425 ENOG4108TN2 lmbE family FOC08_18435 ENOG4107R3E Citrate transporter FOC08_18455 ENOG4108MES Periplasmic binding protein FOC08_18460 ENOG4105EHG Permease protein FOC08_18465 ENOG4105DQ5 transport system permease protein FOC08_18470 ENOG4105NX3 Membrane FOC08_18475 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC08_18495 ENOG4107CUJ Protein of unknown function (DUF2690) FOC08_18505 ENOG4107V2S Transcriptional regulator FOC08_18525 ENOG4105C98 muts2 protein FOC08_18535 ENOG4105E5K Alpha-amylase FOC08_18545 ENOG4105DPN Oligoendopeptidase f FOC08_18550 ENOG4108A04 Beta-lactamase FOC08_18580 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC08_18605 ENOG41082BM Transcriptional regulator, arsr family FOC08_18610 ENOG4105CIS alcohol dehydrogenase FOC08_18635 ENOG4105RHY Pfam:UPF0157 FOC08_18645 ENOG4105C09 Bile acid FOC08_18650 ENOG4105CQB FAD linked oxidase domain protein FOC08_18670 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC08_18680 ENOG4105K64 Glycosyl transferase, family 2 FOC08_18685 ENOG4105E39 Enoyl-CoA hydratase FOC08_18695 ENOG4105KT7 mgtC SapB transporter FOC08_18710 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_18715 ENOG41073R8 VanW family FOC08_18725 ENOG4108R1P FOC08_18740 ENOG4105VEQ Cold shock protein FOC08_18760 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC08_18780 ENOG410904N short-chain dehydrogenase reductase FOC08_18790 ENOG4106IQC argininosuccinate lyase FOC08_18805 ENOG4108IA2 Sodium pantothenate symporter FOC08_18815 ENOG4105C26 Dehydrogenase FOC08_18820 ENOG4105CHR reductase FOC08_18830 ENOG4105EWU Squalene--hopene cyclase FOC08_18840 ENOG4105FR1 rard protein FOC08_18845 ENOG410696E Membrane FOC08_18860 ENOG4105D1F ATP-binding protein FOC08_18870 ENOG4108ZAF Molybdopterin FOC08_18875 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC08_18880 ENOG4105D06 uba thif-type nad fad binding protein FOC08_18885 ENOG4105TMB Formate nitrite transporter FOC08_18895 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC08_18900 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC08_18910 ENOG4108JB9 formate dehydrogenase FOC08_18915 ENOG4105E1K spore germination protein FOC08_18980 ENOG4108KGH TRANSCRIPTIONal FOC08_18990 ENOG4105EMN RNA polymerase sigma factor FOC08_19005 ENOG4105CIG ABC transporter FOC08_19015 ENOG4105D9R oxidoreductase FOC08_19025 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC08_19030 ENOG4105K4P CoA-binding domain protein FOC08_19035 ENOG4105C0H protease FOC08_19040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_19050 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC08_19055 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FOC08_19060 ENOG4105W8X HesB YadR YfhF-family protein FOC08_19090 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC08_19095 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC08_19105 ENOG4108JJA ABC, transporter FOC08_19110 ENOG4108I0Z Aconitate hydratase FOC08_19150 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC08_19170 ENOG4107F3J Amp-dependent synthetase and ligase FOC08_19175 ENOG4107ZYJ bioY protein FOC08_19180 ENOG4105CEY Amp-dependent synthetase and ligase FOC08_19230 ENOG4107AYK membrAne FOC08_19240 ENOG4105BZU Histidine kinase FOC08_19245 ENOG4105FBA Phospholipase Carboxylesterase FOC08_19250 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC08_19255 ENOG4105CK7 Sodium proline symporter FOC08_19260 ENOG4105CBC glutamate synthase FOC08_19265 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC08_19270 ENOG4108VJ1 Transcriptional regulator (CarD family FOC08_19275 ENOG4108903 Formimidoylglutamase FOC08_19300 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FOC08_19360 ENOG4107QIV Cytochrome c biogenesis protein FOC08_19370 ENOG4107RSM transcriptional regulator FOC08_19375 ENOG4105VAW lrga family FOC08_19380 ENOG41067MG lrgb family FOC08_19405 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC08_19420 ENOG4105BZ1 (ABC) transporter FOC08_19425 ENOG4105BZ1 (ABC) transporter FOC08_19445 ENOG4105D7V transposase FOC08_19460 ENOG4105D5T phosphonate abc transporter FOC08_19480 ENOG4108SVB resolvase FOC08_19500 ENOG4105K7K Transcriptional regulator FOC08_19530 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FOC08_19535 ENOG4105XSJ toxin secretion phage lysis holin FOC08_19715 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FOC08_19815 ENOG4105C5F glutamine synthetase FOC08_19820 ENOG4105KV4 Transcriptional regulator FOC08_19825 ENOG4105CXI aluminum resistance protein FOC08_19835 ENOG4105EN6 Membrane FOC08_19845 ENOG4106F1P AAA ATPase, central domain protein FOC08_19875 ENOG41069ER domain protein FOC08_19880 ENOG4105DM4 PTS System FOC08_19885 ENOG4105DE4 1-phosphofructokinase FOC08_19890 ENOG4105E98 transcriptional regulator DeoR family FOC08_19900 ENOG4108SJC Membrane FOC08_19910 ENOG4105C85 amino acid FOC08_19925 ENOG4105TMB Formate nitrite transporter FOC08_19930 ENOG4105K70 DNA-binding protein FOC08_19935 ENOG4105C59 p-type ATPase FOC08_19940 ENOG410681U heavy metal transport detoxification protein FOC08_19945 ENOG4105VPX protein, conserved in bacteria FOC08_19955 ENOG4105NIV Esterase FOC08_19960 ENOG4105E0A ABC, transporter FOC08_19980 ENOG4105CGK Exodeoxyribonuclease III FOC08_19990 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC08_19995 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC08_20025 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC08_20030 ENOG4105BZU Histidine kinase FOC08_20045 ENOG41067MG lrgb family FOC08_20060 ENOG4107TTQ Alpha beta hydrolase fold FOC08_20065 ENOG4107YEI lmbE family FOC08_20090 ENOG4105F0V Cell wall hydrolase FOC08_20095 ENOG4107R6R udp-galactopyranose mutase FOC08_20100 ENOG4105E0M Sulfatase FOC08_20105 ENOG410890F Dynamin family FOC08_20115 ENOG4107QHE Choloylglycine hydrolase FOC08_20140 ENOG4105DA5 (ABC) transporter FOC08_20165 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC08_20170 ENOG4105DQU oxidoreductase, subunit beta FOC08_20175 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC08_20180 ENOG4108IGT Dipeptidase FOC08_20185 ENOG4105MCT stage V sporulation protein S FOC08_20190 ENOG4105D48 metallophosphoesterase FOC08_20215 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC08_20230 ENOG4105XZV Protein of unknown function (DUF3243) FOC08_20235 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC08_20260 ENOG4108JQ9 ABC transporter FOC08_20265 ENOG4105DIH basic membrane FOC08_20270 ENOG4105FDP GntR family transcriptional regulator FOC08_20275 ENOG4107QZI cell division protein FtsK FOC08_20285 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC08_20295 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC08_20305 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC08_20310 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC08_20315 ENOG4105E35 Dipicolinate synthase subunit A FOC08_20325 ENOG4105C1V Peptidase, M16 FOC08_20345 ENOG4105DTN riboflavin biosynthesis protein ribF FOC08_20350 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FOC08_20360 ENOG4105W7A Protein of unknown function (DUF503) FOC08_20370 ENOG4105VHM ribosomal protein FOC08_20375 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC08_20380 ENOG4105CHV Transcription elongation factor NusA FOC08_20390 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC08_20400 ENOG4105DZP Membrane-associated zinc metalloprotease FOC08_20405 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FOC08_20410 ENOG4105KNE Phosphatidate cytidylyltransferase FOC08_20415 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FOC08_20455 ENOG4108HE4 integrase family FOC08_20465 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC08_20475 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC08_20490 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC08_20515 ENOG4105VB6 UPF0109 protein FOC08_20535 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC08_20540 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC08_20555 ENOG4105CHR reductase FOC08_20560 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC08_20575 ENOG4105CB5 ATP-dependent DNA helicase recG FOC08_20580 ENOG4105DP4 dak2 domain fusion protein ylov FOC08_20585 ENOG4108ZAA Alkaline-shock protein FOC08_20600 ENOG4105FJ0 thiamine FOC08_20605 ENOG4105DJV ribulose-phosphate 3-epimerase FOC08_20610 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC08_20615 ENOG4105D9P serine threonine protein kinase FOC08_20620 ENOG4108ZF3 Phosphatase FOC08_20630 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC08_20640 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC08_20645 ENOG4105C25 Primosomal protein n' FOC08_20650 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC08_20670 ENOG4105DSJ YicC domain protein FOC08_20680 ENOG4105F23 Fibronectin-binding protein FOC08_20685 ENOG4105DC7 peptidase M24 FOC08_20740 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FOC08_20765 ENOG4105C34 Pseudouridine synthase FOC08_20780 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FOC08_20790 ENOG4105DBK s4 domain protein FOC08_20795 ENOG41067XK integral membrane protein FOC08_20805 ENOG4105DFA alanine racemase domain protein FOC08_20810 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC08_20815 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC08_20825 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_20835 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC08_20840 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC08_20845 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC08_20850 ENOG4105D4A Cell wall formation (By similarity) FOC08_20855 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FOC08_20860 ENOG4105CNI cell division protein FtsW FOC08_20875 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC08_20880 ENOG4105CJN penicillin-binding protein FOC08_20885 ENOG4105CJN penicillin-binding protein FOC08_20890 ENOG41068DC Essential cell division protein (By similarity) FOC08_20930 ENOG4105KNH Nucleic acid-binding protein FOC08_20980 ENOG4105XSJ toxin secretion phage lysis holin FOC08_21060 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOC08_21070 ENOG4105CAR Terminase, large subunit FOC08_21155 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FOC08_21170 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_21215 ENOG4108IMY Transcriptional regulator FOC08_21235 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) FOC08_21245 ENOG41063PX domain protein FOC08_21250 ENOG4105D78 K07001 NTE family protein FOC08_21255 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC08_21265 ENOG4106H78 methyltransferase FOC08_21285 ENOG4107TB6 phosphoglycerate mutase FOC08_21300 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC08_21350 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC08_21355 ENOG4105CNI cell division protein FtsW FOC08_21370 ENOG4108IAB Phoh family FOC08_21390 ENOG4105QA2 FOC08_21395 ENOG4105CI3 gtp-binding protein typa FOC08_21405 ENOG4105ECY inositol monophosphatase FOC08_21425 ENOG4105CXN decarboxylase FOC08_21470 ENOG4105C7S Dehydrogenase FOC08_21475 ENOG4105CPP Dehydrogenase, E1 component FOC08_21490 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC08_21495 ENOG4108X4Q Hydrolase FOC08_21505 ENOG4105CN5 Metallo-Beta-Lactamase FOC08_21510 ENOG4107ZYR domain protein FOC08_21545 ENOG4108XRC Protein of unknown function (DUF458) FOC08_21550 ENOG4107IN1 Protein of unknown function (DUF1797) FOC08_21565 ENOG4105EPM Diguanylate phosphodiesterase FOC08_21570 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC08_21585 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC08_21595 ENOG4105UIN FOC08_21650 ENOG4108HGU Histidine kinase FOC08_21660 ENOG4105CHM Aminotransferase FOC08_21665 ENOG4105FKQ transcriptional regulator FOC08_21670 ENOG4105EG2 ABC transporter, permease FOC08_21680 ENOG4107FKK extracellular solute-binding protein family 1 FOC08_21690 ENOG4105CG3 alpha amylase, catalytic region FOC08_21735 ENOG4105CHU acetyl-coa acetyltransferase FOC08_21775 ENOG4105K7K Transcriptional regulator FOC08_21780 ENOG4105DTD Dehydrogenase FOC08_21790 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FOC08_21800 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC08_21825 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FOC08_21845 ENOG4106TD9 Diguanylate cyclase FOC08_21865 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC08_21880 ENOG4105CID antiterminator FOC08_21890 ENOG4105FDP GntR family transcriptional regulator FOC08_21900 ENOG4105CE4 GlcNAc 6-P deacetylase FOC08_21935 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC08_21940 ENOG4105PTM secreted protein FOC08_21945 ENOG4105J7I hydrolase FOC08_21955 ENOG4105G6R Stage v sporulation protein ae FOC08_21965 ENOG4105CZ3 stage V sporulation protein ad FOC08_21970 ENOG41090VF Stage v sporulation protein ac FOC08_21990 ENOG4105C8J )-transporter FOC08_21995 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_22005 ENOG41082AN stage II sporulation protein FOC08_22010 ENOG4105DZ1 carboxypeptidase FOC08_22015 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC08_22020 ENOG4105DVE abc transporter atp-binding protein FOC08_22050 ENOG4105D7N magnesium and cobalt transport protein CorA FOC08_22075 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC08_22085 ENOG4105I3K Ferric uptake regulator, Fur family FOC08_22090 ENOG4105MZ9 stage II sporulation protein m FOC08_22110 ENOG4105CPC Aldo Keto reductase FOC08_22120 ENOG4105RHY Pfam:UPF0157 FOC08_22140 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC08_22150 ENOG4105ETE Transcriptional regulator (LacI family FOC08_22155 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC08_22175 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC08_22180 ENOG4108R6K riboflavin synthase, subunit alpha FOC08_22200 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FOC08_22205 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC08_22210 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC08_22215 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FOC08_22225 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC08_22235 ENOG4105DFD Na H antiporter FOC08_22240 ENOG4105CGH 5'-nucleotidase FOC08_22280 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FOC08_22295 ENOG4108IXY short-chain dehydrogenase reductase FOC08_22305 ENOG4105II7 pyrroline-5-carboxylate reductase FOC08_22310 ENOG4105EJQ L-serine dehydratase FOC08_22335 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC08_22345 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC08_22350 ENOG4105D9U N-acetyltransferase FOC08_22365 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC08_22370 ENOG4108QEG Membrane FOC08_22375 ENOG4105CDA abc transporter atp-binding protein FOC08_22380 ENOG4105E5Q amino acid AbC transporter FOC08_22385 ENOG4108HW3 (ABC) transporter FOC08_22395 ENOG4105G7B Protein of unknown function (DUF2992) FOC08_22410 ENOG4105C7S Dehydrogenase FOC08_22415 ENOG4105CPP Dehydrogenase, E1 component FOC08_22435 ENOG4107RDP Dehydrogenase FOC08_22445 ENOG4108JUB Transcriptional regulator FOC08_22455 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC08_22470 ENOG4107QQR Sporulation FOC08_22475 ENOG4105S1Z Stage IV sporulation protein B FOC08_22480 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC08_22490 ENOG4105DX0 Hemolysin A FOC08_22500 ENOG4105CTB Polyprenyl synthetase FOC08_22525 ENOG4108ZSR alkaline shock protein FOC08_22530 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC08_22555 ENOG410644B Stage III sporulation protein af FOC08_22565 ENOG4105KQ4 Stage iii sporulation protein ad FOC08_22570 ENOG4108CQH stage III sporulation protein AC FOC08_22575 ENOG4105KR5 Stage iii sporulation protein FOC08_22580 ENOG4105CD2 stage iii sporulation protein aa FOC08_22605 ENOG4105DC7 peptidase M24 FOC08_22620 ENOG4105CBJ Metal-dependent enzyme FOC08_22630 ENOG4107YBY Hydrolase FOC08_22650 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC08_22655 ENOG4105WZW rhodanese family FOC08_22675 ENOG41080TC multidrug resistance protein FOC08_22710 ENOG4105CJ1 ABC, transporter FOC08_22715 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC08_22745 ENOG4105C0D helicase FOC08_22865 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FOC08_22870 ENOG4105C3R Methionine synthase FOC08_22880 ENOG4105C28 cystathionine FOC08_22885 ENOG4105C28 cystathionine FOC08_22905 ENOG4105C5X domain protein FOC08_22915 ENOG4105DKQ ROK family FOC08_22925 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC08_22940 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC08_22945 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FOC08_22950 ENOG4105E2Z phosphate ABC transporter (Permease FOC08_22955 ENOG4105C8U phosphate abc transporter FOC08_22960 ENOG4105PWN phosphate abc transporter FOC08_22965 ENOG4107RF6 penicillin-binding protein FOC08_22975 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC08_23000 ENOG4105N80 Ferric uptake regulator, Fur family FOC08_23010 ENOG4105FDK ABC transporter FOC08_23015 ENOG4108JYZ YitT family FOC08_23020 ENOG41069ZM Protein of unknown function (DUF2624) FOC08_23045 ENOG4105EGD dinuclear metal center protein, YbgI family FOC08_23060 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_23065 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC08_23090 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC08_23095 ENOG4105KG3 cytidine deaminase FOC08_23100 ENOG4107YR5 Diacylglycerol kinase FOC08_23110 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC08_23115 ENOG4105C9A Phoh family FOC08_23125 ENOG41068P3 sporulation protein YqfC FOC08_23130 ENOG4105KTH gatB Yqey FOC08_23140 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC08_23145 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC08_23165 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FOC08_23175 ENOG4105CSA Coproporphyrinogen iii oxidase FOC08_23180 ENOG4105KVH Transcriptional regulator FOC08_23205 ENOG4105TQK DNA polymerase iii, delta' subunit FOC08_23215 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC08_23220 ENOG4108UK2 deaminase FOC08_23225 ENOG4105KQC Competence protein FOC08_23235 ENOG4105DXX methyltransferase FOC08_23245 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC08_23255 ENOG410812S Rna-binding protein FOC08_23265 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC08_23270 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC08_23285 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC08_23305 ENOG4108TVJ Nitroreductase FOC08_23320 ENOG4105G6Z alkaline phosphatase FOC08_23330 ENOG4108MUZ hydrolase FOC08_23365 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC08_23370 ENOG4105MIR Phenylalanine 4-monooxygenase FOC08_23420 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC08_23425 ENOG4108V5C ABC transporter FOC08_23435 ENOG4108EKI Dehydrogenase FOC08_23440 ENOG4105C28 cystathionine FOC08_23470 ENOG4107XRG penicillin-binding protein FOC08_23485 ENOG4105CFP Peptidase U32 FOC08_23490 ENOG4105XYU peptidase (U32 family) FOC08_23495 ENOG4108VQJ O-methyltransferase FOC08_23500 ENOG4105HHA aminodeoxychorismate lyase FOC08_23520 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC08_23530 ENOG4105C02 permease FOC08_23545 ENOG41060CR FOC08_23550 ENOG4105C7H Helicase, RecD TraA family FOC08_23560 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FOC08_23565 ENOG4105C3J Cysteine desulfurase FOC08_23575 ENOG4105D1H recombination factor protein RarA FOC08_23580 ENOG4108VCI transcription factor, rsfa family FOC08_23585 ENOG4105CUZ uba thif-type nad fad binding protein FOC08_23595 ENOG4105CUT histidyl-tRNA synthetase FOC08_23605 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC08_23615 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC08_23620 ENOG41076HS cation diffusion facilitator family transporter FOC08_23625 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC08_23635 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC08_23640 ENOG4108QG2 Membrane FOC08_23650 ENOG4105VIE preprotein translocase, subunit YajC FOC08_23665 ENOG41061AI Protein of unknown function (DUF2905) FOC08_23680 ENOG4108HUF Transporter FOC08_23690 ENOG4108IPJ Membrane FOC08_23695 ENOG4108IPJ Membrane FOC08_23700 ENOG41082BM Transcriptional regulator, arsr family FOC08_23725 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC08_23730 ENOG4108IYU L-aspartate oxidase FOC08_23745 ENOG4108RPX mosc domain containing protein FOC08_23750 ENOG4105CQC Prephenate dehydratase FOC08_23780 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FOC08_23795 ENOG4105X36 (ribosomal) protein FOC08_23805 ENOG4105C03 ribonuclease FOC08_23820 ENOG4107QMS site-determining protein FOC08_23835 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FOC08_23840 ENOG4105DFF Rod shape-determining protein mreb FOC08_23860 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC08_23865 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FOC08_23875 ENOG41068KH stage VI sporulation protein D FOC08_23885 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC08_23910 ENOG4105K56 Transcriptional regulator FOC08_23930 ENOG4108IUQ atp-dependent protease FOC08_23955 ENOG4108QCI YvbH-like oligomerisation region FOC08_23975 ENOG4105M59 Phosphodiesterase, mj0936 family FOC08_23980 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FOC08_23990 ENOG4108XJQ germination protein FOC08_24000 ENOG4108PCX Major Facilitator FOC08_24010 ENOG4105KBX Transcriptional regulator, TetR family FOC08_24025 ENOG4105PFC Transcriptional regulator FOC08_24040 ENOG4105DZC cytosine deaminase FOC08_24045 ENOG4105DZC cytosine deaminase FOC08_24050 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC08_24055 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC08_24070 ENOG4108JQ7 (ABC) transporter FOC08_24080 ENOG4105DY9 regulatoR FOC08_24095 ENOG41067S9 phage shock protein C, PspC FOC08_24100 ENOG4108JCI Transcriptional regulator FOC08_24110 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC08_24115 ENOG4108Z40 Transcriptional regulator FOC08_24120 ENOG4105RHA ABC transporter, permease FOC08_24125 ENOG4108IUX (ABC) transporter FOC08_24130 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC08_24140 ENOG4105E14 MotA TolQ exbB proton channel FOC08_24145 ENOG4108VXD carboxy-peptidase FOC08_24155 ENOG4105E33 succinate dehydrogenase FOC08_24165 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC08_24180 ENOG4105K63 Thioredoxin FOC08_24185 ENOG4105C10 Electron transfer flavoprotein FOC08_24190 ENOG4105BZJ Electron transfer flavoprotein FOC08_24195 ENOG41060WC Enoyl-CoA hydratase FOC08_24200 ENOG4107Z3H Transcriptional regulator, TetR family FOC08_24205 ENOG4105CEY Amp-dependent synthetase and ligase FOC08_24215 ENOG4105J76 Periplasmic binding protein FOC08_24220 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC08_24260 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_24270 ENOG4105DR4 Methyltransferase FOC08_24285 ENOG4105KFN sortase, SrtB family FOC08_24290 ENOG4105E0A ABC, transporter FOC08_24305 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC08_24315 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC08_24325 ENOG4105FE9 pseudouridine synthase FOC08_24335 ENOG4105DCG PHP domain protein FOC08_24370 ENOG4105C5S asparaginyl-tRNA synthetase FOC08_24375 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FOC08_24385 ENOG4108RWN rrna methyltransferase FOC08_24420 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC08_24425 ENOG4105CW7 secretion protein, HlyD family FOC08_24430 ENOG4108JGH Tetr family transcriptional regulator FOC08_24435 ENOG4105CN9 Peptidase m42 family protein FOC08_24455 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FOC08_24460 ENOG4105C22 threonyL-tRNA synthetase FOC08_24465 ENOG4108TDW sporulation protein YtxC FOC08_24485 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) FOC08_24495 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC08_24500 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOC08_24510 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FOC08_24515 ENOG4105C2M dna polymerase I FOC08_24520 ENOG4105BZU Histidine kinase FOC08_24525 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_24540 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC08_24545 ENOG4105BZN citrate synthase FOC08_24555 ENOG4108REF Sporulation integral membrane protein ytvi FOC08_24560 ENOG4105FS0 cytoplasmic membrane protein FOC08_24585 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC08_24590 ENOG4105C6K Malic enzyme FOC08_24595 ENOG4105C0B DNA polymerase III (alpha subunit) FOC08_24600 ENOG4105VV2 FOC08_24610 ENOG4105SFS phosphoesterase RecJ domain protein FOC08_24645 ENOG4105DC7 peptidase M24 FOC08_24680 ENOG4105Z7P Acetyltransferase (GNAT) family FOC08_24685 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC08_24695 ENOG4105VZ8 Transcriptional regulator FOC08_24715 ENOG4107YZX Universal stress protein FOC08_24755 ENOG4108JYZ YitT family FOC08_24775 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FOC08_24785 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC08_24790 ENOG4105KBJ sporulation protein ytfj FOC08_24805 ENOG4105EFZ amidohydrolase FOC08_24815 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC08_24840 ENOG4106KR7 LysR family Transcriptional regulator FOC08_24860 ENOG4105C28 cystathionine FOC08_24880 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC08_24890 ENOG4105EMN RNA polymerase sigma factor FOC08_24910 ENOG4105F1V Acetoin utilization protein FOC08_24915 ENOG4105W87 Cbs domain FOC08_24920 ENOG4105DGU Histone deacetylase FOC08_24930 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC08_24940 ENOG4107SNB ankyrin repeat protein YahD FOC08_24945 ENOG4105EP9 oxidoreductase FOC08_24975 ENOG4105ETE Transcriptional regulator (LacI family FOC08_24995 ENOG4105C88 aminopeptidase FOC08_25040 ENOG4108VDD TRNA binding domain protein FOC08_25070 ENOG4105C8F Beta-lactamase domain protein FOC08_25085 ENOG4108V15 phosphotransferase enzyme family FOC08_25090 ENOG4108IUM Glycogen debranching enzyme FOC08_25105 ENOG4105YW5 deoR family transcriptional regulator FOC08_25120 ENOG4105CBX hi0933 family FOC08_25155 ENOG4108VJ1 Transcriptional regulator (CarD family FOC08_25160 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC08_25165 ENOG4105CSC Glucose uptake protein FOC08_25180 ENOG4108ZAF Molybdopterin FOC08_25185 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC08_25190 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC08_25200 ENOG4105D06 uba thif-type nad fad binding protein FOC08_25225 ENOG41085GJ domain protein FOC08_25235 ENOG4105DWV Homoserine O-trans-acetylase FOC08_25245 ENOG4108B31 Spore germination protein FOC08_25275 ENOG410605W Major Facilitator FOC08_25280 ENOG4107S91 Sodium hydrogen exchanger FOC08_25285 ENOG4105NCW Trka-c domain protein FOC08_25300 ENOG4105C19 ABC transporter FOC08_25320 ENOG4105N5T Radical SAM Protein FOC08_25330 ENOG4105DA5 (ABC) transporter FOC08_25360 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC08_25365 ENOG4108Z0R Transferase FOC08_25370 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC08_25375 ENOG4105BZF Glycosyl transferase (Group 1 FOC08_25385 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC08_25435 ENOG4105EGD dinuclear metal center protein, YbgI family FOC08_25440 ENOG4105BZU Histidine kinase FOC08_25445 ENOG4105BZU Histidine kinase FOC08_25450 ENOG4107S9D Alpha beta hydrolase FOC08_25470 ENOG4105D2X ABC transporter substrate-binding protein FOC08_25480 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC08_25535 ENOG4108V2W Carbonate dehydratase FOC08_25540 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC08_25545 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC08_25590 ENOG41087YS Phage shock protein A FOC08_25625 ENOG4105BZU Histidine kinase FOC08_25630 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_25655 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC08_25660 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC08_25695 ENOG4107ZTW SNARE associated Golgi FOC08_25710 ENOG4105C19 ABC transporter FOC08_25715 ENOG41086D8 Transcriptional regulator FOC08_25755 ENOG4105C6Z Gluconate FOC08_25760 ENOG4105FDP GntR family transcriptional regulator FOC08_25780 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC08_25810 ENOG4105DTQ mandelate racemase muconate lactonizing FOC08_25820 ENOG4108IPT Naphthoate synthase FOC08_25825 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC08_25830 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) FOC08_25835 ENOG4105E4F Isochorismate synthase FOC08_25840 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC08_25850 ENOG4105VEQ Cold shock protein FOC08_25870 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FOC08_25880 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FOC08_25900 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC08_25995 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC08_26030 ENOG4105KT7 mgtC SapB transporter FOC08_26035 ENOG4107PBV potassium channel FOC08_26045 ENOG4107QYV phosphohexose isomerase FOC08_26050 ENOG4105WG9 Conserved Protein FOC08_26060 ENOG4105CHM Aminotransferase FOC08_26065 ENOG4108ZB6 transcriptional regulator AsnC family FOC08_26070 ENOG4105C5I Dehydrogenase FOC08_26075 ENOG4108MUZ hydrolase FOC08_26085 ENOG4105C87 Aminotransferase class I and II FOC08_26095 ENOG4105Y38 Kinase-associated protein B FOC08_26105 ENOG4107R3E Citrate transporter FOC08_26120 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) FOC08_26125 ENOG4105KA0 thioesterase Superfamily protein FOC08_26145 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC08_26165 ENOG41069ER domain protein FOC08_26180 ENOG4105CEP NADH dehydrogenase FOC08_26210 ENOG4105EWC Purine nucleoside phosphorylase FOC08_26230 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC08_26255 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC08_26260 ENOG4105C4B ABC transporter, permease FOC08_26265 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC08_26310 ENOG41083MR nifu domain-containing protein FOC08_26325 ENOG4108W5N phosphatidylglycerophosphatase a FOC08_26335 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC08_26340 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC08_26355 ENOG4105CBT Fructose-1,6-bisphosphatase FOC08_26370 ENOG4105MMD transcriptional regulator FOC08_26375 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC08_26380 ENOG4107TXC Transcriptional regulator FOC08_26385 ENOG41090T1 Membrane FOC08_26410 ENOG4105FAA peptidase M23 FOC08_26420 ENOG4105KZD Domain of unknown function (DUF1805) FOC08_26425 ENOG4107R8B 5'-nucleotidase FOC08_26440 ENOG4105DIW FeS assembly protein SUFB FOC08_26445 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC08_26450 ENOG4105C9B Cysteine desulfurase FOC08_26455 ENOG4105JRK feS assembly protein SufD FOC08_26460 ENOG4105C3K feS assembly ATPase SufC FOC08_26465 ENOG4105D01 (LipO)protein FOC08_26470 ENOG4105D01 (LipO)protein FOC08_26475 ENOG4108UMI ABC transporter, permease FOC08_26510 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC08_26555 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC08_26580 ENOG4108W8B Beta-lactamase domain protein FOC08_26585 ENOG4105C1G acyl-Coa dehydrogenase FOC08_26590 ENOG4105CHU acetyl-coa acetyltransferase FOC08_26605 ENOG4105DZ1 carboxypeptidase FOC08_26625 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC08_26640 ENOG4108SUT Major Facilitator Superfamily FOC08_26645 ENOG4107R7I amino acid FOC08_26655 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC08_26665 ENOG4107AYK membrAne FOC08_26700 ENOG4107ZTW SNARE associated Golgi FOC08_26710 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC08_26715 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC08_26720 ENOG4105BZU Histidine kinase FOC08_26730 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FOC08_26745 ENOG4105VG1 fes assembly suf system protein FOC08_26750 ENOG4105D4Y metalloprotease FOC08_26770 ENOG4107S91 Sodium hydrogen exchanger FOC08_26775 ENOG4105NCW Trka-c domain protein FOC08_26785 ENOG4108RMU ferritin dps family protein FOC08_26800 ENOG4108URH decarboxylase FOC08_26820 ENOG4105D9N nucleoside FOC08_26825 ENOG4105D9N nucleoside FOC08_26840 ENOG4108RYK Nad-dependent epimerase dehydratase FOC08_26855 ENOG4105CV8 reductase FOC08_26860 ENOG4105F27 Major Facilitator FOC08_26865 ENOG4105KVH Transcriptional regulator FOC08_26880 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC08_26885 ENOG4105D4A Cell wall formation (By similarity) FOC08_26895 ENOG4105C8Q Methyl-accepting chemotaxis FOC08_26905 ENOG4105WMR Protein CrcB homolog FOC08_26910 ENOG4105WMR Protein CrcB homolog FOC08_26925 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC08_26930 ENOG4108VY7 phosphate-starvation-inducible protein PsiE FOC08_26945 ENOG4108IPW abc transporter atp-binding protein FOC08_26950 ENOG4105CM4 permease protein FOC08_26980 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC08_26990 ENOG4105XZU Preprotein translocase, subunit SecG FOC08_26995 ENOG41067MG lrgb family FOC08_27085 ENOG4108QY5 Ferric enterobactin transport protein