locus-tag	class	description
FOC12_00005	COG3403	YqcI/YcgG family
FOC12_00010	COG5577	PFAM Coat F domain
FOC12_00025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_00030	COG3848	Pyruvate phosphate dikinase
FOC12_00030	COG0574	Belongs to the PEP-utilizing enzyme family
FOC12_00045	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC12_00075	COG1960	acyl-CoA dehydrogenase activity
FOC12_00085	COG0640	Transcriptional regulator
FOC12_00090	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC12_00105	COG1414	Transcriptional regulator
FOC12_00110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC12_00115	COG1984	allophanate hydrolase subunit 2
FOC12_00145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC12_00190	COG4335	DNA alkylation repair
FOC12_00200	COG0833	amino acid
FOC12_00210	COG0730	response to heat
FOC12_00240	COG0596	Alpha beta hydrolase
FOC12_00245	COG0745	RESPONSE REGULATOR receiver
FOC12_00250	COG0642	Histidine kinase
FOC12_00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_00290	COG0456	acetyltransferase
FOC12_00295	COG2207	Transcriptional regulator
FOC12_00320	COG0577	efflux transmembrane transporter activity
FOC12_00320	COG1136	(ABC) transporter
FOC12_00330	COG1725	Transcriptional regulator
FOC12_00365	COG1846	Transcriptional regulator
FOC12_00370	COG0778	Nitroreductase
FOC12_00380	COG0714	Associated with various cellular activities
FOC12_00405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC12_00415	COG0753	catalase activity
FOC12_00420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC12_00430	COG0463	Glycosyl transferase, family 2
FOC12_00455	COG0463	Glycosyl transferase, family 2
FOC12_00480	COG0714	Associated with various cellular activities
FOC12_00500	COG0346	lactoylglutathione lyase activity
FOC12_00505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_00515	COG3279	Response regulator of the LytR AlgR family
FOC12_00525	COG4377	Putative membrane peptidase family (DUF2324)
FOC12_00540	COG3655	Transcriptional regulator
FOC12_00550	COG1785	Belongs to the alkaline phosphatase family
FOC12_00555	COG3239	Fatty acid desaturase
FOC12_00560	COG1690	Belongs to the RtcB family
FOC12_00565	COG0833	amino acid
FOC12_00570	COG1414	Transcriptional regulator
FOC12_00575	COG4187	Peptidase family M20/M25/M40
FOC12_00580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC12_00585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC12_00595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_00615	COG2329	Antibiotic biosynthesis monooxygenase
FOC12_00650	COG2390	Transcriptional regulator
FOC12_00660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC12_00670	COG1879	ABC-type sugar transport system periplasmic component
FOC12_00695	COG1595	DNA-templated transcription, initiation
FOC12_00705	COG1388	LysM domain
FOC12_00705	COG3584	3D domain protein
FOC12_00740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC12_00740	COG1605	Chorismate mutase
FOC12_00745	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC12_00750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC12_00755	COG0287	Prephenate dehydrogenase
FOC12_00770	COG1309	transcriptional regulator
FOC12_00775	COG2409	Drug exporters of the RND superfamily
FOC12_00775	COG1033	growth of symbiont in host cell
FOC12_00780	COG1033	growth of symbiont in host cell
FOC12_00780	COG2409	Drug exporters of the RND superfamily
FOC12_00785	COG1033	growth of symbiont in host cell
FOC12_00785	COG2409	Drug exporters of the RND superfamily
FOC12_00795	COG0488	(ABC) transporter
FOC12_00800	COG1368	sulfuric ester hydrolase activity
FOC12_00805	COG0861	Integral membrane protein TerC family
FOC12_00815	COG0726	polysaccharide deacetylase
FOC12_00825	COG4912	Dna alkylation repair
FOC12_00845	COG2318	DinB family
FOC12_00850	COG0697	spore germination
FOC12_00875	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC12_00915	COG1116	anion transmembrane transporter activity
FOC12_00920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC12_00925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC12_00930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC12_00940	COG0628	permease
FOC12_01000	COG5146	pantothenate kinase activity
FOC12_01005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC12_01010	COG0436	Aminotransferase
FOC12_01045	COG2226	methyltransferase
FOC12_01060	COG2261	transglycosylase associated protein
FOC12_01080	COG2814	Major facilitator Superfamily
FOC12_01080	COG0477	Major facilitator Superfamily
FOC12_01085	COG4533	DNA binding
FOC12_01090	COG0789	Transcriptional regulator
FOC12_01095	COG1664	Polymer-forming cytoskeletal
FOC12_01105	COG2814	Major facilitator Superfamily
FOC12_01125	COG1307	EDD domain protein, DegV family
FOC12_01140	COG1164	Oligoendopeptidase f
FOC12_01180	COG5002	protein histidine kinase activity
FOC12_01185	COG2936	dipeptidyl-peptidase activity
FOC12_01230	COG4948	Mandelate Racemase Muconate Lactonizing
FOC12_01240	COG4166	transmembrane transport
FOC12_01245	COG0519	Catalyzes the synthesis of GMP from XMP
FOC12_01250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC12_01265	COG0586	Pfam SNARE associated Golgi protein
FOC12_01305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC12_01310	COG3938	Belongs to the proline racemase family
FOC12_01320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC12_01325	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_01330	COG1115	amino acid carrier protein
FOC12_01335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC12_01350	COG3397	chitin binding
FOC12_01375	COG4637	Psort location Cytoplasmic, score
FOC12_01395	COG0514	ATP-dependent DNA helicase (RecQ)
FOC12_01400	COG2105	PFAM AIG2 family protein
FOC12_01415	COG3973	AAA domain
FOC12_01465	COG2333	competence protein COMEC
FOC12_01465	COG0658	competence protein
FOC12_01485	COG2205	protein histidine kinase activity
FOC12_01500	COG3397	chitin binding
FOC12_01505	COG2153	protein acetylation
FOC12_01510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC12_01525	COG0740	serine-type endopeptidase activity
FOC12_01535	COG0517	IMP dehydrogenase activity
FOC12_01535	COG4175	Glycine betaine
FOC12_01540	COG4176	ABC-type proline glycine betaine transport system permease component
FOC12_01570	COG0456	acetyltransferase
FOC12_01570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC12_01575	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_01585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC12_01590	COG0022	dehydrogenase e1 component
FOC12_01595	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC12_01600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC12_01615	COG1959	2 iron, 2 sulfur cluster binding
FOC12_01635	COG1349	DNA-binding transcription factor activity
FOC12_01650	COG3284	Transcriptional regulator
FOC12_01680	COG1309	transcriptional regulator
FOC12_01685	COG3844	kynureninase activity
FOC12_01690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC12_01695	COG3483	tryptophan 2,3-dioxygenase activity
FOC12_01710	COG3409	Peptidoglycan-binding domain 1 protein
FOC12_01710	COG3773	Cell wall hydrolase
FOC12_01715	COG2959	enzyme of heme biosynthesis
FOC12_01730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_01735	COG4129	membrane
FOC12_01765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_01770	COG0697	spore germination
FOC12_01780	COG0201	protein transport
FOC12_01800	COG3227	Zinc metalloprotease (Elastase)
FOC12_01805	COG1523	belongs to the glycosyl hydrolase 13 family
FOC12_01820	COG0076	glutamate decarboxylase activity
FOC12_01840	COG1011	Hydrolase
FOC12_01865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC12_01905	COG0322	excinuclease ABC activity
FOC12_01920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC12_01970	COG3878	Protein conserved in bacteria
FOC12_02005	COG1051	belongs to the nudix hydrolase family
FOC12_02010	COG0592	DNA-directed DNA polymerase activity
FOC12_02015	COG2816	NAD+ diphosphatase activity
FOC12_02030	COG2223	nitrite transmembrane transporter activity
FOC12_02060	COG0697	spore germination
FOC12_02080	COG0584	glycerophosphoryl diester phosphodiesterase
FOC12_02095	COG2814	Major facilitator Superfamily
FOC12_02125	COG0693	protein deglycase activity
FOC12_02160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC12_02175	COG0604	alcohol dehydrogenase
FOC12_02190	COG2205	protein histidine kinase activity
FOC12_02205	COG1122	ATPase activity
FOC12_02215	COG1794	racemase activity, acting on amino acids and derivatives
FOC12_02220	COG1819	glycosyl
FOC12_02230	COG5002	protein histidine kinase activity
FOC12_02240	COG0561	phosphatase activity
FOC12_02275	COG2124	cytochrome p450
FOC12_02340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC12_02350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_02355	COG0460	homoserine dehydrogenase
FOC12_02380	COG1136	(ABC) transporter
FOC12_02410	COG0745	RESPONSE REGULATOR receiver
FOC12_02420	COG3773	Cell wall hydrolase
FOC12_02445	COG1063	alcohol dehydrogenase
FOC12_02460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_02480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC12_02495	COG2814	Major facilitator Superfamily
FOC12_02505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC12_02520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC12_02520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC12_02560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC12_02585	COG1686	Belongs to the peptidase S11 family
FOC12_02590	COG2318	DinB family
FOC12_02600	COG0572	uridine kinase
FOC12_02605	COG1247	-acetyltransferase
FOC12_02615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC12_02620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC12_02625	COG1024	Enoyl-CoA hydratase
FOC12_02630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC12_02635	COG0511	ligase activity, forming carbon-carbon bonds
FOC12_02640	COG0439	Biotin carboxylase
FOC12_02645	COG1960	acyl-CoA dehydrogenase activity
FOC12_02660	COG1309	transcriptional regulator
FOC12_02670	COG1131	(ABC) transporter
FOC12_02685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_02690	COG1252	NADH dehydrogenase
FOC12_02705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_02725	COG1309	transcriptional regulator
FOC12_02745	COG1876	peptidase activity
FOC12_02760	COG1476	TRANSCRIPTIONal
FOC12_02765	COG0457	Tetratricopeptide repeat
FOC12_02790	COG3718	enzyme involved in inositol metabolism
FOC12_02810	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_02820	COG0673	inositol 2-dehydrogenase activity
FOC12_02825	COG2814	Major facilitator Superfamily
FOC12_02830	COG1609	Transcriptional regulator
FOC12_02835	COG0671	phosphoesterase, PA-phosphatase related
FOC12_02840	COG2367	Beta-lactamase
FOC12_02850	COG0768	penicillin binding
FOC12_02860	COG1595	DNA-templated transcription, initiation
FOC12_02875	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC12_02905	COG1846	Transcriptional regulator
FOC12_02910	COG3961	Belongs to the TPP enzyme family
FOC12_02915	COG2226	methyltransferase
FOC12_02925	COG0500	methyltransferase
FOC12_02925	COG3615	Tellurite resistance protein tehB
FOC12_02930	COG1136	(ABC) transporter
FOC12_02930	COG0577	efflux transmembrane transporter activity
FOC12_02945	COG1309	transcriptional regulator
FOC12_02975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_02995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC12_03000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC12_03005	COG2971	BadF BadG BcrA BcrD
FOC12_03055	COG1595	DNA-templated transcription, initiation
FOC12_03085	COG1396	sequence-specific DNA binding
FOC12_03105	COG1132	(ABC) transporter
FOC12_03110	COG1132	(ABC) transporter
FOC12_03125	COG2258	MOSC domain
FOC12_03130	COG0583	DNA-binding transcription factor activity
FOC12_03145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC12_03150	COG0583	DNA-binding transcription factor activity
FOC12_03190	COG0561	phosphatase activity
FOC12_03195	COG0010	Belongs to the arginase family
FOC12_03210	COG1278	Cold shock
FOC12_03220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_03260	COG1247	-acetyltransferase
FOC12_03295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_03340	COG2226	methyltransferase
FOC12_03360	COG2814	Major facilitator Superfamily
FOC12_03365	COG0596	Alpha beta hydrolase
FOC12_03380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC12_03385	COG1187	pseudouridine synthase activity
FOC12_03390	COG2329	Antibiotic biosynthesis monooxygenase
FOC12_03405	COG1115	amino acid carrier protein
FOC12_03415	COG2318	DinB family
FOC12_03425	COG0776	regulation of translation
FOC12_03440	COG2814	Major facilitator Superfamily
FOC12_03445	COG3251	PFAM MbtH domain protein
FOC12_03450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC12_03455	COG3433	isochorismatase activity
FOC12_03455	COG1535	isochorismatase
FOC12_03460	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC12_03465	COG1169	isochorismate synthase
FOC12_03470	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_03475	COG2223	nitrite transmembrane transporter activity
FOC12_03495	COG0419	ATPase involved in DNA repair
FOC12_03500	COG0420	3'-5' exonuclease activity
FOC12_03515	COG1024	Enoyl-CoA hydratase
FOC12_03520	COG1280	lysine exporter protein (LysE YggA)
FOC12_03525	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_03530	COG2084	Dehydrogenase
FOC12_03535	COG1960	acyl-CoA dehydrogenase activity
FOC12_03540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC12_03545	COG2079	MmgE PrpD family protein
FOC12_03550	COG0372	Belongs to the citrate synthase family
FOC12_03555	COG4841	protein insertion into membrane
FOC12_03560	COG2814	Major facilitator Superfamily
FOC12_03565	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC12_03565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC12_03605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC12_03695	COG1715	Restriction endonuclease
FOC12_03695	COG1787	Restriction endonuclease
FOC12_03725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC12_03730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC12_03735	COG0671	phosphoesterase, PA-phosphatase related
FOC12_03740	COG4326	sporulation control protein
FOC12_03780	COG1509	lysine 2,3-aminomutase activity
FOC12_03785	COG3829	transcription factor binding
FOC12_03790	COG0456	acetyltransferase
FOC12_03795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC12_03800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC12_03805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC12_03810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC12_03825	COG5506	Protein of unknown function (DUF1694)
FOC12_03830	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_03835	COG1253	flavin adenine dinucleotide binding
FOC12_03870	COG1174	glycine betaine transport
FOC12_03875	COG0517	IMP dehydrogenase activity
FOC12_03875	COG1125	glycine betaine transport
FOC12_03905	COG1070	Carbohydrate kinase
FOC12_03930	COG1064	alcohol dehydrogenase
FOC12_03940	COG2197	response regulator
FOC12_03945	COG2203	Gaf domain
FOC12_03945	COG4585	Histidine kinase
FOC12_03950	COG0668	transmembrane transport
FOC12_03960	COG1051	belongs to the nudix hydrolase family
FOC12_03985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC12_03990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_04005	COG0367	asparagine synthase
FOC12_04010	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC12_04015	COG1999	signal sequence binding
FOC12_04020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC12_04025	COG1307	EDD domain protein, DegV family
FOC12_04035	COG0805	protein transport
FOC12_04045	COG1272	protein, Hemolysin III
FOC12_04050	COG0204	Acyl-transferase
FOC12_04055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC12_04060	COG0768	penicillin binding
FOC12_04075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC12_04095	COG0546	phosphoglycolate phosphatase activity
FOC12_04110	COG1131	(ABC) transporter
FOC12_04125	COG0456	acetyltransferase
FOC12_04135	COG1794	racemase activity, acting on amino acids and derivatives
FOC12_04140	COG1454	alcohol dehydrogenase
FOC12_04145	COG2610	gluconate transmembrane transporter activity
FOC12_04170	COG0733	neurotransmitter:sodium symporter activity
FOC12_04185	COG5002	protein histidine kinase activity
FOC12_04185	COG3850	Histidine kinase
FOC12_04190	COG0745	RESPONSE REGULATOR receiver
FOC12_04195	COG0471	metal ion transport
FOC12_04200	COG1929	Belongs to the glycerate kinase type-1 family
FOC12_04270	COG1674	ftsk spoiiie
FOC12_04290	COG0017	Asparaginyl-tRNA synthetase
FOC12_04310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC12_04335	COG0018	arginyl-trna synthetase
FOC12_04340	COG2521	methyltransferase
FOC12_04340	COG2136	Putative SAM-dependent methyltransferase
FOC12_04355	COG1413	lyase activity
FOC12_04370	COG0629	single-stranded DNA binding
FOC12_04385	COG0488	(ABC) transporter
FOC12_04390	COG1418	mRNA catabolic process
FOC12_04405	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC12_04420	COG2359	stage V sporulation protein S
FOC12_04455	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC12_04460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC12_04465	COG2146	nitrite reductase [NAD(P)H] activity
FOC12_04470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC12_04470	COG1587	Uroporphyrinogen-III synthase
FOC12_04480	COG1648	precorrin-2 dehydrogenase activity
FOC12_04495	COG2223	nitrite transmembrane transporter activity
FOC12_04505	COG0314	molybdopterin synthase activity
FOC12_04510	COG0303	'Molybdopterin
FOC12_04515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC12_04520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC12_04525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC12_04545	COG2181	nitrate reductase activity
FOC12_04550	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC12_04555	COG1140	nitrate reductase beta subunit
FOC12_04560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC12_04575	COG0714	Associated with various cellular activities
FOC12_04580	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC12_04585	COG1305	Transglutaminase-like
FOC12_04590	COG0386	Belongs to the glutathione peroxidase family
FOC12_04615	COG1595	DNA-templated transcription, initiation
FOC12_04620	COG0604	alcohol dehydrogenase
FOC12_04630	COG0346	lactoylglutathione lyase activity
FOC12_04655	COG2226	methyltransferase
FOC12_04680	COG3874	Sporulation protein YtfJ
FOC12_04730	COG0456	acetyltransferase
FOC12_04755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_04760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_04765	COG1819	glycosyl
FOC12_04785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC12_04795	COG0561	phosphatase activity
FOC12_04815	COG2211	Major facilitator Superfamily
FOC12_04820	COG0154	amidase activity
FOC12_04830	COG1876	peptidase activity
FOC12_04840	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC12_04860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_04865	COG1114	Component of the transport system for branched-chain amino acids
FOC12_04880	COG1253	flavin adenine dinucleotide binding
FOC12_04885	COG2839	Protein conserved in bacteria
FOC12_04890	COG0702	epimerase
FOC12_04905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC12_04915	COG1607	acyl-coa hydrolase
FOC12_04920	COG3689	TIGRFAM TIGR03943 family protein
FOC12_04925	COG0701	Predicted permease
FOC12_04935	COG2244	polysaccharide biosynthetic process
FOC12_04940	COG0586	Pfam SNARE associated Golgi protein
FOC12_04945	COG1051	belongs to the nudix hydrolase family
FOC12_04950	COG5337	Spore coat protein CotH
FOC12_04960	COG0406	alpha-ribazole phosphatase activity
FOC12_04975	COG4166	transmembrane transport
FOC12_04985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC12_04995	COG0702	epimerase
FOC12_05000	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC12_05000	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC12_05050	COG0456	acetyltransferase
FOC12_05055	COG0523	cobalamin synthesis protein
FOC12_05060	COG4989	oxidoreductase activity
FOC12_05070	COG1231	oxidoreductase activity
FOC12_05080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC12_05095	COG0783	Belongs to the Dps family
FOC12_05100	COG3949	Membrane
FOC12_05115	COG0840	transmembrane signaling receptor activity
FOC12_05140	COG2814	Major facilitator Superfamily
FOC12_05145	COG0667	Aldo Keto reductase
FOC12_05150	COG0640	Transcriptional regulator
FOC12_05155	COG1404	Belongs to the peptidase S8 family
FOC12_05160	COG2002	toxin-antitoxin pair type II binding
FOC12_05200	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC12_05210	COG1279	arginine transmembrane transporter activity
FOC12_05225	COG1082	Xylose isomerase domain protein TIM barrel
FOC12_05240	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_05245	COG4264	IucA IucC family
FOC12_05255	COG1247	-acetyltransferase
FOC12_05260	COG1285	pathogenesis
FOC12_05270	COG0726	polysaccharide deacetylase
FOC12_05275	COG5002	protein histidine kinase activity
FOC12_05280	COG0745	RESPONSE REGULATOR receiver
FOC12_05290	COG1316	TRANSCRIPTIONal
FOC12_05315	COG0460	homoserine dehydrogenase
FOC12_05335	COG0726	polysaccharide deacetylase
FOC12_05350	COG0300	oxidoreductase activity
FOC12_05360	COG5002	protein histidine kinase activity
FOC12_05365	COG0745	RESPONSE REGULATOR receiver
FOC12_05380	COG0791	NLP P60 protein
FOC12_05380	COG1388	LysM domain
FOC12_05395	COG1686	Belongs to the peptidase S11 family
FOC12_05415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC12_05420	COG4988	ABC transporter
FOC12_05425	COG1294	oxidase, subunit
FOC12_05430	COG1271	oxidase subunit
FOC12_05440	COG1846	Transcriptional regulator
FOC12_05460	COG0583	DNA-binding transcription factor activity
FOC12_05480	COG0411	ABC transporter
FOC12_05490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_05495	COG2030	dehydratase
FOC12_05500	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_05515	COG0523	cobalamin synthesis protein
FOC12_05520	COG1231	oxidoreductase activity
FOC12_05525	COG0039	L-malate dehydrogenase activity
FOC12_05530	COG0628	permease
FOC12_05540	COG0778	Nitroreductase
FOC12_05545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC12_05550	COG1959	2 iron, 2 sulfur cluster binding
FOC12_05555	COG0583	DNA-binding transcription factor activity
FOC12_05560	COG0697	spore germination
FOC12_05570	COG4549	nuclear export factor GLE1
FOC12_05575	COG2372	response to copper ion
FOC12_05575	COG1276	copper resistance
FOC12_05590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC12_05620	COG2132	Multicopper oxidase
FOC12_05625	COG0006	proline dipeptidase activity
FOC12_05645	COG4224	UPF0291 protein
FOC12_05660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC12_05665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_05675	COG2390	Transcriptional regulator
FOC12_05705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC12_05720	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC12_05740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_05775	COG1073	alpha beta
FOC12_05795	COG0427	acetyl-CoA hydrolase
FOC12_05800	COG3279	Response regulator of the LytR AlgR family
FOC12_05810	COG3384	dioxygenase
FOC12_05815	COG2814	Major facilitator Superfamily
FOC12_05840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC12_05850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC12_05855	COG0440	acetolactate synthase activity
FOC12_05860	COG0028	Belongs to the TPP enzyme family
FOC12_05865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC12_05875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC12_05890	COG2084	Dehydrogenase
FOC12_05905	COG2323	membrane
FOC12_05910	COG5566	PFAM Mor transcription activator
FOC12_05920	COG0733	neurotransmitter:sodium symporter activity
FOC12_05925	COG2244	polysaccharide biosynthetic process
FOC12_05940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC12_05945	COG2223	nitrite transmembrane transporter activity
FOC12_05965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_05980	COG1966	Carbon starvation protein
FOC12_06005	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC12_06010	COG1051	belongs to the nudix hydrolase family
FOC12_06060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC12_06065	COG0784	Response regulator, receiver
FOC12_06070	COG4191	Histidine kinase
FOC12_06075	COG0281	malic enzyme
FOC12_06080	COG1027	Aspartate ammonia-lyase
FOC12_06090	COG0528	UMP kinase activity
FOC12_06095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC12_06110	COG1131	(ABC) transporter
FOC12_06145	COG2733	membrane
FOC12_06175	COG0785	Cytochrome C biogenesis protein
FOC12_06195	COG3340	Belongs to the peptidase S51 family
FOC12_06220	COG0114	fumarate hydratase activity
FOC12_06225	COG1757	Na H antiporter
FOC12_06230	COG1216	Glycosyl transferase, family 2
FOC12_06230	COG0438	transferase activity, transferring glycosyl groups
FOC12_06240	COG0701	Predicted permease
FOC12_06245	COG0523	cobalamin synthesis protein
FOC12_06250	COG0697	spore germination
FOC12_06255	COG1802	Transcriptional regulator
FOC12_06285	COG0367	asparagine synthase
FOC12_06315	COG0406	alpha-ribazole phosphatase activity
FOC12_06325	COG1686	Belongs to the peptidase S11 family
FOC12_06355	COG1234	tRNA 3'-trailer cleavage
FOC12_06360	COG1177	transmembrane transport
FOC12_06365	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC12_06370	COG3842	ATPase activity
FOC12_06400	COG2329	Antibiotic biosynthesis monooxygenase
FOC12_06420	COG1309	transcriptional regulator
FOC12_06445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC12_06450	COG4786	Flagellar basal body rod
FOC12_06460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC12_06465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC12_06475	COG1987	bacterial-type flagellum assembly
FOC12_06480	COG1338	Plays a role in the flagellum-specific transport system
FOC12_06490	COG1776	CheC inhibitor of MCP methylation
FOC12_06490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC12_06505	COG0741	lytic transglycosylase activity
FOC12_06510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC12_06545	COG0463	Glycosyl transferase, family 2
FOC12_06595	COG1157	protein secretion by the type III secretion system
FOC12_06605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC12_06615	COG1677	Flagellar hook-basal body complex protein FliE
FOC12_06620	COG1558	bacterial-type flagellum-dependent cell motility
FOC12_06625	COG1815	bacterial-type flagellum-dependent cell motility
FOC12_06650	COG1256	bacterial-type flagellum assembly
FOC12_06670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC12_06685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC12_06685	COG1776	CheC inhibitor of MCP methylation
FOC12_06695	COG2201	protein-glutamate methylesterase activity
FOC12_06700	COG1360	Flagellar Motor Protein
FOC12_06705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC12_06715	COG1923	regulation of RNA biosynthetic process
FOC12_06770	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC12_06775	COG2323	membrane
FOC12_06785	COG0789	Transcriptional regulator
FOC12_06785	COG4978	Transcriptional regulator
FOC12_06795	COG0475	glutathione-regulated potassium exporter activity
FOC12_06805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC12_06810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC12_06815	COG3162	membrane
FOC12_06830	COG1280	lysine exporter protein (LysE YggA)
FOC12_06870	COG0328	RNA-DNA hybrid ribonuclease activity
FOC12_06890	COG0454	-acetyltransferase
FOC12_06910	COG1215	transferase activity, transferring glycosyl groups
FOC12_06925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC12_06950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC12_07000	COG0456	acetyltransferase
FOC12_07010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC12_07020	COG2311	Membrane
FOC12_07025	COG2233	PERMEase
FOC12_07040	COG0024	Methionine aminopeptidase
FOC12_07045	COG3173	Aminoglycoside phosphotransferase
FOC12_07055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC12_07060	COG1199	ATP-dependent helicase activity
FOC12_07070	COG0116	Belongs to the methyltransferase superfamily
FOC12_07085	COG4474	Belongs to the UPF0398 family
FOC12_07125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC12_07125	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC12_07135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC12_07140	COG3935	DnaD domain protein
FOC12_07160	COG1199	ATP-dependent helicase activity
FOC12_07160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC12_07195	COG0438	transferase activity, transferring glycosyl groups
FOC12_07200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC12_07215	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC12_07220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_07230	COG2738	Putative neutral zinc metallopeptidase
FOC12_07245	COG4347	Protein of unknown function (DUF1405)
FOC12_07255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC12_07275	COG0457	Tetratricopeptide repeat
FOC12_07280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC12_07295	COG0105	UTP biosynthetic process
FOC12_07300	COG0142	geranyltranstransferase activity
FOC12_07310	COG0142	geranyltranstransferase activity
FOC12_07325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC12_07400	COG0492	ferredoxin-NADP+ reductase activity
FOC12_07420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC12_07425	COG4862	establishment of competence for transformation
FOC12_07445	COG1266	CAAX protease self-immunity
FOC12_07450	COG0514	ATP-dependent DNA helicase (RecQ)
FOC12_07455	COG4955	Helix-turn-helix domain
FOC12_07460	COG1141	Ferredoxin
FOC12_07465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC12_07480	COG2096	Adenosyltransferase
FOC12_07485	COG5002	protein histidine kinase activity
FOC12_07490	COG0745	RESPONSE REGULATOR receiver
FOC12_07495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC12_07500	COG1333	cytochrome c biogenesis protein
FOC12_07510	COG1187	pseudouridine synthase activity
FOC12_07515	COG0700	Nucleoside recognition
FOC12_07520	COG2715	membrane protein required for spore maturation
FOC12_07525	COG1686	Belongs to the peptidase S11 family
FOC12_07530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC12_07545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC12_07545	COG0392	lysyltransferase activity
FOC12_07565	COG5002	protein histidine kinase activity
FOC12_07570	COG0582	viral genome integration into host DNA
FOC12_07580	COG1801	Protein of unknown function DUF72
FOC12_07600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC12_07605	COG1392	Phosphate transport regulator
FOC12_07610	COG0306	phosphate transporter
FOC12_07615	COG0730	response to heat
FOC12_07630	COG1017	nitric oxide dioxygenase activity
FOC12_07630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC12_07655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC12_07665	COG1114	Component of the transport system for branched-chain amino acids
FOC12_07675	COG2197	response regulator
FOC12_07680	COG4585	Histidine kinase
FOC12_07685	COG4758	membrane
FOC12_07700	COG1757	Na H antiporter
FOC12_07720	COG0733	neurotransmitter:sodium symporter activity
FOC12_07725	COG1648	precorrin-2 dehydrogenase activity
FOC12_07745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC12_07750	COG0529	Catalyzes the synthesis of activated sulfate
FOC12_07770	COG0019	diaminopimelate decarboxylase activity
FOC12_07780	COG1368	sulfuric ester hydrolase activity
FOC12_07785	COG1183	phosphatidylcholine synthase activity
FOC12_07800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC12_07835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC12_07860	COG0473	3-isopropylmalate dehydrogenase activity
FOC12_07870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC12_07875	COG0440	acetolactate synthase activity
FOC12_07880	COG0028	Belongs to the TPP enzyme family
FOC12_07885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC12_07910	COG3874	Sporulation protein YtfJ
FOC12_07915	COG4709	membrane
FOC12_07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC12_07925	COG1301	dicarboxylic acid transport
FOC12_07935	COG1846	Transcriptional regulator
FOC12_07950	COG1968	undecaprenyl-diphosphatase activity
FOC12_07955	COG0534	Mate efflux family protein
FOC12_07970	COG3173	Aminoglycoside phosphotransferase
FOC12_07980	COG0716	FMN binding
FOC12_08000	COG1696	Membrane protein involved in D-alanine export
FOC12_08010	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC12_08015	COG2070	2-Nitropropane dioxygenase
FOC12_08020	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC12_08030	COG1335	isochorismatase
FOC12_08040	COG1522	sequence-specific DNA binding
FOC12_08055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC12_08060	COG1131	(ABC) transporter
FOC12_08070	COG1131	(ABC) transporter
FOC12_08075	COG1725	Transcriptional regulator
FOC12_08080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC12_08100	COG1780	Probably involved in ribonucleotide reductase function
FOC12_08125	COG4873	Protein conserved in bacteria
FOC12_08140	COG0720	synthase
FOC12_08150	COG5002	protein histidine kinase activity
FOC12_08155	COG2318	DinB family
FOC12_08165	COG1846	Transcriptional regulator
FOC12_08170	COG3852	Histidine kinase
FOC12_08180	COG2861	carbohydrate metabolic process
FOC12_08200	COG1349	DNA-binding transcription factor activity
FOC12_08215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC12_08230	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC12_08240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC12_08250	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC12_08255	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_08275	COG2030	dehydratase
FOC12_08285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC12_08290	COG0861	Integral membrane protein TerC family
FOC12_08295	COG2116	formate transmembrane transporter activity
FOC12_08305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC12_08325	COG2186	Transcriptional regulator
FOC12_08330	COG5002	protein histidine kinase activity
FOC12_08335	COG0745	RESPONSE REGULATOR receiver
FOC12_08345	COG3835	regulator
FOC12_08350	COG0277	FAD linked oxidase domain protein
FOC12_08355	COG0247	lactate metabolic process
FOC12_08360	COG2340	Cysteine-rich secretory protein family
FOC12_08370	COG0564	pseudouridine synthase activity
FOC12_08380	COG2409	Drug exporters of the RND superfamily
FOC12_08390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC12_08395	COG1177	transmembrane transport
FOC12_08400	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC12_08405	COG3842	ATPase activity
FOC12_08410	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_08445	COG0681	Belongs to the peptidase S26 family
FOC12_08450	COG1686	Belongs to the peptidase S11 family
FOC12_08460	COG2226	methyltransferase
FOC12_08520	COG1476	TRANSCRIPTIONal
FOC12_08530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC12_08585	COG5634	Uncharacterized conserved protein (DUF2278)
FOC12_08590	COG1620	l-lactate permease
FOC12_08625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC12_08625	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC12_08635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC12_08640	COG5492	domain, Protein
FOC12_08655	COG2382	esterase
FOC12_08660	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC12_08665	COG2153	protein acetylation
FOC12_08710	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC12_08725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC12_08745	COG0463	Glycosyl transferase, family 2
FOC12_08745	COG0457	Tetratricopeptide repeat
FOC12_08765	COG1216	Glycosyl transferase, family 2
FOC12_08785	COG0564	pseudouridine synthase activity
FOC12_08790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC12_08795	COG2357	RelA SpoT domain protein
FOC12_08805	COG4116	CYTH
FOC12_08810	COG2346	COG2346, Truncated hemoglobins
FOC12_08820	COG1164	Oligoendopeptidase f
FOC12_08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC12_08835	COG4862	establishment of competence for transformation
FOC12_08840	COG0861	Integral membrane protein TerC family
FOC12_08845	COG1393	Belongs to the ArsC family
FOC12_08855	COG4166	transmembrane transport
FOC12_08860	COG0534	Mate efflux family protein
FOC12_08865	COG4608	Belongs to the ABC transporter superfamily
FOC12_08870	COG0444	Belongs to the ABC transporter superfamily
FOC12_08875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC12_08880	COG0601	transmembrane transport
FOC12_08885	COG4166	transmembrane transport
FOC12_08895	COG0180	Tryptophanyl-tRNA synthetase
FOC12_08905	COG5504	Zn-dependent protease
FOC12_08910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC12_08915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_08930	COG2267	carboxylic ester hydrolase activity
FOC12_08940	COG0542	response to heat
FOC12_08950	COG0561	phosphatase activity
FOC12_08965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_08975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC12_08985	COG2996	Protein conserved in bacteria
FOC12_09010	COG0753	catalase activity
FOC12_09020	COG0367	asparagine synthase
FOC12_09045	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC12_09090	COG1074	ATP-dependent DNA helicase activity
FOC12_09095	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC12_09105	COG0398	Pfam SNARE associated Golgi protein
FOC12_09110	COG4903	ComK protein
FOC12_09125	COG1278	Cold shock
FOC12_09135	COG2224	Isocitrate lyase
FOC12_09140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC12_09145	COG0497	DNA recombination
FOC12_09160	COG0697	spore germination
FOC12_09165	COG0840	transmembrane signaling receptor activity
FOC12_09170	COG0501	Belongs to the peptidase M48B family
FOC12_09195	COG0745	RESPONSE REGULATOR receiver
FOC12_09200	COG2205	protein histidine kinase activity
FOC12_09210	COG2207	Transcriptional regulator
FOC12_09210	COG3708	Transcriptional regulator
FOC12_09215	COG1595	DNA-templated transcription, initiation
FOC12_09225	COG1078	dGTPase activity
FOC12_09260	COG3209	COG3209 Rhs family protein
FOC12_09290	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_09300	COG0095	Lipoate-protein ligase
FOC12_09305	COG1234	tRNA 3'-trailer cleavage
FOC12_09315	COG1609	Transcriptional regulator
FOC12_09340	COG1511	domain protein
FOC12_09345	COG1309	transcriptional regulator
FOC12_09390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC12_09395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC12_09400	COG2329	Antibiotic biosynthesis monooxygenase
FOC12_09405	COG3428	Bacterial PH domain
FOC12_09410	COG3402	PFAM membrane-flanked domain
FOC12_09455	COG3402	PFAM membrane-flanked domain
FOC12_09460	COG1309	transcriptional regulator
FOC12_09475	COG4473	ABC transporter
FOC12_09480	COG1131	(ABC) transporter
FOC12_09485	COG0537	adenosine 5'-monophosphoramidase activity
FOC12_09490	COG4980	gas vesicle protein
FOC12_09510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC12_09515	COG3973	AAA domain
FOC12_09525	COG0477	Major facilitator Superfamily
FOC12_09530	COG0477	Major facilitator Superfamily
FOC12_09565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC12_09575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC12_09580	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC12_09600	COG2267	carboxylic ester hydrolase activity
FOC12_09605	COG0457	Tetratricopeptide repeat
FOC12_09610	COG0346	lactoylglutathione lyase activity
FOC12_09615	COG0346	lactoylglutathione lyase activity
FOC12_09620	COG2814	Major facilitator Superfamily
FOC12_09625	COG1309	transcriptional regulator
FOC12_09650	COG0420	3'-5' exonuclease activity
FOC12_09680	COG0393	Putative heavy-metal-binding
FOC12_09700	COG2205	protein histidine kinase activity
FOC12_09700	COG2198	Histidine kinase
FOC12_09700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC12_09700	COG0784	Response regulator, receiver
FOC12_09705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC12_09710	COG2208	phosphoserine phosphatase activity
FOC12_09720	COG1191	sigma factor activity
FOC12_09745	COG3237	CsbD-like
FOC12_09795	COG3437	response regulator, receiver
FOC12_09795	COG2770	Histidine kinase
FOC12_09825	COG1959	2 iron, 2 sulfur cluster binding
FOC12_09830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC12_09835	COG2376	Dihydroxyacetone kinase
FOC12_09845	COG2376	Dihydroxyacetone kinase
FOC12_09865	COG1183	phosphatidylcholine synthase activity
FOC12_09890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC12_09890	COG3320	Male sterility
FOC12_09935	COG0477	Major facilitator Superfamily
FOC12_09965	COG0305	Participates in initiation and elongation during chromosome replication
FOC12_09980	COG0789	Transcriptional regulator
FOC12_09980	COG4978	Transcriptional regulator
FOC12_10010	COG3181	Tripartite tricarboxylate transporter family receptor
FOC12_10015	COG4565	transcriptional regulatory protein
FOC12_10020	COG3290	protein histidine kinase activity
FOC12_10025	COG0477	Major facilitator Superfamily
FOC12_10055	COG0322	excinuclease ABC activity
FOC12_10060	COG4608	Belongs to the ABC transporter superfamily
FOC12_10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC12_10075	COG0601	transmembrane transport
FOC12_10110	COG3938	Belongs to the proline racemase family
FOC12_10130	COG1363	Peptidase, m42
FOC12_10150	COG1024	Enoyl-CoA hydratase
FOC12_10165	COG1696	Membrane protein involved in D-alanine export
FOC12_10180	COG4196	transglutaminase domain protein
FOC12_10185	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC12_10195	COG2244	polysaccharide biosynthetic process
FOC12_10200	COG0653	protein targeting
FOC12_10220	COG0659	secondary active sulfate transmembrane transporter activity
FOC12_10235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC12_10250	COG0561	phosphatase activity
FOC12_10265	COG3527	Alpha-acetolactate decarboxylase
FOC12_10270	COG0028	Belongs to the TPP enzyme family
FOC12_10300	COG0189	ligase activity
FOC12_10315	COG1126	abc transporter atp-binding protein
FOC12_10320	COG0765	amino acid transport
FOC12_10325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC12_10335	COG1132	(ABC) transporter
FOC12_10340	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_10350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC12_10355	COG0531	amino acid
FOC12_10365	COG0693	protein deglycase activity
FOC12_10365	COG0753	catalase activity
FOC12_10370	COG0693	protein deglycase activity
FOC12_10380	COG2211	Major facilitator Superfamily
FOC12_10385	COG4533	DNA binding
FOC12_10390	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC12_10400	COG1733	regulation of RNA biosynthetic process
FOC12_10405	COG2814	Major facilitator Superfamily
FOC12_10410	COG1309	transcriptional regulator
FOC12_10415	COG2076	Multidrug Resistance protein
FOC12_10420	COG2076	Multidrug Resistance protein
FOC12_10430	COG1522	sequence-specific DNA binding
FOC12_10435	COG0697	spore germination
FOC12_10450	COG2259	Doxx family
FOC12_10460	COG1263	PTS System
FOC12_10460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_10470	COG1737	Transcriptional regulator
FOC12_10480	COG0475	glutathione-regulated potassium exporter activity
FOC12_10485	COG0531	amino acid
FOC12_10515	COG0586	Pfam SNARE associated Golgi protein
FOC12_10550	COG3546	catalase activity
FOC12_10555	COG1114	Component of the transport system for branched-chain amino acids
FOC12_10570	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC12_10580	COG1136	(ABC) transporter
FOC12_10585	COG0577	efflux transmembrane transporter activity
FOC12_10590	COG3584	3D domain protein
FOC12_10590	COG1388	LysM domain
FOC12_10610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC12_10615	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC12_10620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC12_10620	COG3711	transcriptional antiterminator
FOC12_10635	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC12_10640	COG0604	alcohol dehydrogenase
FOC12_10645	COG1316	TRANSCRIPTIONal
FOC12_10655	COG0730	response to heat
FOC12_10660	COG2210	Belongs to the sulfur carrier protein TusA family
FOC12_10670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_10675	COG0425	Belongs to the sulfur carrier protein TusA family
FOC12_10680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_10680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_10685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_10685	COG0425	Belongs to the sulfur carrier protein TusA family
FOC12_10690	COG1937	Protein conserved in bacteria
FOC12_10695	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC12_10720	COG2719	SpoVR family
FOC12_10725	COG0778	Nitroreductase
FOC12_10760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC12_10765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC12_10775	COG1609	Transcriptional regulator
FOC12_10780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_10780	COG1263	PTS System
FOC12_10785	COG1621	beta-fructofuranosidase activity
FOC12_10790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC12_10805	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_10810	COG2252	PERMEase
FOC12_10825	COG1846	Transcriptional regulator
FOC12_10830	COG2814	Major facilitator Superfamily
FOC12_10835	COG2205	protein histidine kinase activity
FOC12_10875	COG0351	phosphomethylpyrimidine kinase
FOC12_10880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC12_10890	COG2104	thiamine diphosphate biosynthetic process
FOC12_10895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC12_10900	COG0352	thiamine-phosphate diphosphorylase activity
FOC12_10905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC12_10910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC12_10915	COG1116	anion transmembrane transporter activity
FOC12_10920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC12_10940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC12_11055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC12_11065	COG0581	inorganic phosphate transmembrane transporter activity
FOC12_11070	COG0573	inorganic phosphate transmembrane transporter activity
FOC12_11075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC12_11080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC12_11080	COG1918	ferrous iron import across plasma membrane
FOC12_11085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC12_11090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC12_11100	COG0531	amino acid
FOC12_11105	COG0697	spore germination
FOC12_11110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC12_11125	COG4990	cell redox homeostasis
FOC12_11130	COG0833	amino acid
FOC12_11135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC12_11140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC12_11155	COG0475	glutathione-regulated potassium exporter activity
FOC12_11155	COG0569	domain protein
FOC12_11180	COG2252	PERMEase
FOC12_11185	COG1113	amino acid transport
FOC12_11200	COG1114	Component of the transport system for branched-chain amino acids
FOC12_11205	COG3104	oligopeptide transport
FOC12_11220	COG1476	TRANSCRIPTIONal
FOC12_11225	COG3584	3D domain protein
FOC12_11225	COG1388	LysM domain
FOC12_11230	COG0840	transmembrane signaling receptor activity
FOC12_11235	COG1968	undecaprenyl-diphosphatase activity
FOC12_11260	COG3568	Endonuclease Exonuclease Phosphatase
FOC12_11275	COG1063	alcohol dehydrogenase
FOC12_11295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC12_11300	COG1879	ABC-type sugar transport system periplasmic component
FOC12_11305	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC12_11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC12_11325	COG1609	Transcriptional regulator
FOC12_11335	COG1846	Transcriptional regulator
FOC12_11340	COG2271	Major facilitator Superfamily
FOC12_11350	COG4608	Belongs to the ABC transporter superfamily
FOC12_11355	COG0601	transmembrane transport
FOC12_11365	COG0747	negative chemotaxis
FOC12_11380	COG0659	secondary active sulfate transmembrane transporter activity
FOC12_11395	COG5002	protein histidine kinase activity
FOC12_11400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC12_11405	COG2378	regulation of single-species biofilm formation
FOC12_11430	COG0833	amino acid
FOC12_11435	COG0765	amino acid transport
FOC12_11440	COG0765	amino acid transport
FOC12_11445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC12_11450	COG1126	abc transporter atp-binding protein
FOC12_11455	COG1115	amino acid carrier protein
FOC12_11460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC12_11470	COG0697	spore germination
FOC12_11485	COG0366	Alpha amylase catalytic
FOC12_11490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_11490	COG1263	PTS System
FOC12_11495	COG2188	Transcriptional regulator
FOC12_11500	COG0531	amino acid
FOC12_11520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC12_11525	COG0714	Associated with various cellular activities
FOC12_11530	COG4548	von Willebrand factor, type A
FOC12_11540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC12_11545	COG0156	8-amino-7-oxononanoate synthase activity
FOC12_11550	COG2226	methyltransferase
FOC12_11560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_11565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_11570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_11575	COG3104	oligopeptide transport
FOC12_11590	COG1620	l-lactate permease
FOC12_11595	COG1027	Aspartate ammonia-lyase
FOC12_11600	COG1253	flavin adenine dinucleotide binding
FOC12_11605	COG0346	lactoylglutathione lyase activity
FOC12_11610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_11615	COG1316	TRANSCRIPTIONal
FOC12_11620	COG2720	vancomycin resistance protein
FOC12_11640	COG3227	Zinc metalloprotease (Elastase)
FOC12_11655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC12_11660	COG2217	Heavy metal translocating P-type atpase
FOC12_11665	COG0640	Transcriptional regulator
FOC12_11670	COG0531	amino acid
FOC12_11685	COG2427	Protein of unknown function (DUF1641)
FOC12_11690	COG3383	formate dehydrogenase (NAD+) activity
FOC12_11695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC12_11700	COG0454	-acetyltransferase
FOC12_11700	COG0456	acetyltransferase
FOC12_11705	COG0745	RESPONSE REGULATOR receiver
FOC12_11710	COG5002	protein histidine kinase activity
FOC12_11720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_11735	COG0281	malic enzyme
FOC12_11740	COG3493	citrate carrier protein
FOC12_11745	COG4565	transcriptional regulatory protein
FOC12_11750	COG3290	protein histidine kinase activity
FOC12_11760	COG4990	cell redox homeostasis
FOC12_11770	COG5002	protein histidine kinase activity
FOC12_11775	COG0745	RESPONSE REGULATOR receiver
FOC12_11780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC12_11790	COG0395	ABC-type sugar transport system, permease component
FOC12_11795	COG1175	transmembrane transport
FOC12_11800	COG3842	ATPase activity
FOC12_11805	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC12_11825	COG2851	Citrate transporter
FOC12_11835	COG3290	protein histidine kinase activity
FOC12_11845	COG2268	Band 7 protein
FOC12_11850	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC12_11860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC12_11880	COG2766	serine protein kinase
FOC12_11890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC12_11900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC12_11910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC12_11915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC12_12030	COG0735	belongs to the Fur family
FOC12_12035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC12_12055	COG4555	ABC transporter
FOC12_12065	COG0070	glutamate synthase
FOC12_12065	COG0069	glutamate synthase activity
FOC12_12065	COG0067	glutamate synthase
FOC12_12070	COG4129	membrane
FOC12_12075	COG1132	(ABC) transporter
FOC12_12100	COG1194	a g-specific adenine glycosylase
FOC12_12105	COG1988	membrane-bound metal-dependent
FOC12_12135	COG1090	epimerase
FOC12_12140	COG1228	amidohydrolase
FOC12_12160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC12_12180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC12_12180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC12_12195	COG0463	Glycosyl transferase, family 2
FOC12_12210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC12_12215	COG1263	PTS System
FOC12_12215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_12220	COG2066	Belongs to the glutaminase family
FOC12_12240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC12_12245	COG0833	amino acid
FOC12_12255	COG3829	transcription factor binding
FOC12_12265	COG0101	tRNA pseudouridine synthase activity
FOC12_12470	COG1484	DNA-dependent DNA replication
FOC12_12505	COG1396	sequence-specific DNA binding
FOC12_12520	COG1396	sequence-specific DNA binding
FOC12_12525	COG0582	viral genome integration into host DNA
FOC12_12530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC12_12535	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC12_12560	COG0535	radical SAM domain protein
FOC12_12570	COG0387	Pfam Sodium calcium exchanger
FOC12_12575	COG3871	stress protein (general stress protein 26)
FOC12_12590	COG0586	Pfam SNARE associated Golgi protein
FOC12_12610	COG0697	spore germination
FOC12_12615	COG2217	Heavy metal translocating P-type atpase
FOC12_12620	COG1295	ribonuclease BN
FOC12_12630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC12_12645	COG3853	Toxic anion resistance protein (TelA)
FOC12_12655	COG0861	Integral membrane protein TerC family
FOC12_12660	COG2310	stress, protein
FOC12_12665	COG2310	stress, protein
FOC12_12670	COG2310	stress, protein
FOC12_12685	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC12_12700	COG2270	Major facilitator Superfamily
FOC12_12745	COG0488	(ABC) transporter
FOC12_12750	COG1116	anion transmembrane transporter activity
FOC12_12760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC12_12775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC12_12805	COG2190	(PTS) system
FOC12_12805	COG1263	PTS System
FOC12_12805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_12810	COG0366	Alpha amylase catalytic
FOC12_12815	COG0840	transmembrane signaling receptor activity
FOC12_12820	COG0840	transmembrane signaling receptor activity
FOC12_12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC12_12835	COG0765	amino acid transport
FOC12_12845	COG0723	plastoquinol--plastocyanin reductase activity
FOC12_12845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC12_12850	COG2814	Major facilitator Superfamily
FOC12_12855	COG3541	Predicted nucleotidyltransferase
FOC12_12875	COG5002	protein histidine kinase activity
FOC12_12910	COG0166	Belongs to the GPI family
FOC12_12925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_12930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_12935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_12940	COG0235	Class ii aldolase
FOC12_12950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC12_12955	COG0450	alkyl hydroperoxide reductase
FOC12_12970	COG1473	amidohydrolase
FOC12_13000	COG4807	Protein conserved in bacteria
FOC12_13010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC12_13015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC12_13020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_13035	COG2309	aminopeptidase activity
FOC12_13040	COG2076	Multidrug Resistance protein
FOC12_13045	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_13055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC12_13060	COG0546	phosphoglycolate phosphatase activity
FOC12_13065	COG1597	lipid kinase activity
FOC12_13090	COG1846	Transcriptional regulator
FOC12_13110	COG1464	Belongs to the NlpA lipoprotein family
FOC12_13115	COG2011	ABC-type metal ion transport system permease component
FOC12_13120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC12_13125	COG1335	isochorismatase
FOC12_13140	COG4851	CamS sex pheromone cAM373 precursor
FOC12_13150	COG0210	DNA helicase
FOC12_13175	COG0151	Belongs to the GarS family
FOC12_13185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC12_13195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC12_13210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC12_13220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC12_13225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC12_13230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC12_13250	COG0745	RESPONSE REGULATOR receiver
FOC12_13255	COG2205	protein histidine kinase activity
FOC12_13270	COG1968	undecaprenyl-diphosphatase activity
FOC12_13310	COG2226	methyltransferase
FOC12_13345	COG5002	protein histidine kinase activity
FOC12_13355	COG2252	PERMEase
FOC12_13375	COG1266	CAAX protease self-immunity
FOC12_13390	COG0488	(ABC) transporter
FOC12_13395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC12_13400	COG0456	acetyltransferase
FOC12_13405	COG1214	PFAM Peptidase M22, glycoprotease
FOC12_13410	COG0802	atpase or kinase
FOC12_13505	COG2183	response to ionizing radiation
FOC12_13510	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC12_13515	COG0864	Transcriptional regulator
FOC12_13520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC12_13525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC12_13535	COG0705	Rhomboid family
FOC12_13535	COG0457	Tetratricopeptide repeat
FOC12_13540	COG4294	response to UV
FOC12_13550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC12_13560	COG2814	Major facilitator Superfamily
FOC12_13570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC12_13575	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC12_13595	COG4608	Belongs to the ABC transporter superfamily
FOC12_13600	COG0444	Belongs to the ABC transporter superfamily
FOC12_13610	COG0601	transmembrane transport
FOC12_13615	COG0747	negative chemotaxis
FOC12_13630	COG0488	(ABC) transporter
FOC12_13650	COG5298	Protein conserved in bacteria
FOC12_13655	COG0084	hydrolase, TatD family'
FOC12_13665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_13675	COG1609	Transcriptional regulator
FOC12_13685	COG0204	Acyl-transferase
FOC12_13700	COG0697	spore germination
FOC12_13705	COG0583	DNA-binding transcription factor activity
FOC12_13715	COG1910	domain protein
FOC12_13725	COG4149	molybdate abc transporter
FOC12_13730	COG4975	Glucose uptake
FOC12_13740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC12_13745	COG0656	L-ascorbic acid biosynthetic process
FOC12_13750	COG4166	transmembrane transport
FOC12_13755	COG4166	transmembrane transport
FOC12_13770	COG2207	Transcriptional regulator
FOC12_13780	COG4166	transmembrane transport
FOC12_13785	COG4608	Belongs to the ABC transporter superfamily
FOC12_13790	COG0444	Belongs to the ABC transporter superfamily
FOC12_13795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC12_13800	COG0601	transmembrane transport
FOC12_13815	COG2814	Major facilitator Superfamily
FOC12_13825	COG2271	Major facilitator Superfamily
FOC12_13830	COG0277	FAD linked oxidase domain protein
FOC12_13845	COG1464	Belongs to the NlpA lipoprotein family
FOC12_13850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC12_13855	COG2011	ABC-type metal ion transport system permease component
FOC12_13890	COG4946	Tricorn protease homolog
FOC12_13890	COG0823	Involved in the tonB-independent uptake of proteins
FOC12_13890	COG1506	peptidase
FOC12_13895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC12_13915	COG0596	Alpha beta hydrolase
FOC12_13920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC12_13935	COG4856	YbbR-like protein
FOC12_13940	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC12_14020	COG0726	polysaccharide deacetylase
FOC12_14025	COG2194	sulfuric ester hydrolase activity
FOC12_14035	COG0489	protein tyrosine kinase activity
FOC12_14040	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC12_14060	COG0101	tRNA pseudouridine synthase activity
FOC12_14065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC12_14070	COG1122	ATPase activity
FOC12_14100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC12_14110	COG0024	Methionine aminopeptidase
FOC12_14120	COG0201	protein transport
FOC12_14145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC12_14250	COG1358	cellular component organization or biogenesis
FOC12_14255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC12_14265	COG2813	Specifically methylates the guanine in position
FOC12_14290	COG0250	Participates in transcription elongation, termination and antitermination
FOC12_14295	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC12_14300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC12_14310	COG3688	RNA-binding protein containing a PIN domain
FOC12_14315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC12_14330	COG1045	serine acetyltransferase
FOC12_14350	COG4956	integral membrane protein (PIN domain superfamily)
FOC12_14360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC12_14365	COG0542	response to heat
FOC12_14375	COG3880	PFAM UvrB UvrC protein
FOC12_14405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC12_14410	COG1396	sequence-specific DNA binding
FOC12_14415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC12_14420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC12_14425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC12_14430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC12_14435	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC12_14440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC12_14445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC12_14460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC12_14470	COG0037	tRNA processing
FOC12_14475	COG2208	phosphoserine phosphatase activity
FOC12_14490	COG1098	S1 RNA binding domain
FOC12_14510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC12_14515	COG3956	TIGRFAM MazG family protein
FOC12_14520	COG2244	polysaccharide biosynthetic process
FOC12_14525	COG2002	toxin-antitoxin pair type II binding
FOC12_14530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC12_14540	COG0193	aminoacyl-tRNA hydrolase activity
FOC12_14545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC12_14560	COG0251	oxidation-reduction process
FOC12_14565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC12_14580	COG4466	Protein conserved in bacteria
FOC12_14595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC12_14600	COG0084	hydrolase, TatD family'
FOC12_14605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_14605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_14610	COG2002	toxin-antitoxin pair type II binding
FOC12_14615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC12_14625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC12_14635	COG1774	PSP1 C-terminal conserved region
FOC12_14640	COG0470	DNA polymerase III
FOC12_14650	COG1982	Orn Lys Arg decarboxylase major
FOC12_14705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC12_14715	COG0590	tRNA wobble adenosine to inosine editing
FOC12_14720	COG1335	isochorismatase
FOC12_14725	COG1428	Deoxynucleoside kinase
FOC12_14730	COG1428	Deoxynucleoside kinase
FOC12_14760	COG1686	Belongs to the peptidase S11 family
FOC12_14765	COG0516	GMP reductase activity
FOC12_14765	COG0517	IMP dehydrogenase activity
FOC12_14800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC12_14805	COG0187	DNA topoisomerase II activity
FOC12_14815	COG2501	S4 domain
FOC12_14820	COG0592	DNA-directed DNA polymerase activity
FOC12_14840	COG0706	membrane insertase activity
FOC12_14845	COG1847	R3H domain protein
FOC12_14850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC12_14870	COG1192	Involved in chromosome partitioning
FOC12_14875	COG1475	DNA binding
FOC12_14885	COG0668	transmembrane transport
FOC12_14890	COG4481	Protein conserved in bacteria
FOC12_14895	COG0012	GTP binding
FOC12_14905	COG0629	single-stranded DNA binding
FOC12_14915	COG4241	membrane
FOC12_14920	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC12_14930	COG0305	Participates in initiation and elongation during chromosome replication
FOC12_14960	COG0745	RESPONSE REGULATOR receiver
FOC12_14965	COG5002	protein histidine kinase activity
FOC12_14970	COG4863	YycH protein
FOC12_14975	COG4853	Protein conserved in bacteria
FOC12_14980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC12_14985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC12_15005	COG1164	Oligoendopeptidase f
FOC12_15010	COG0516	GMP reductase activity
FOC12_15030	COG1272	protein, Hemolysin III
FOC12_15035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC12_15055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC12_15060	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC12_15065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC12_15070	COG2814	Major facilitator Superfamily
FOC12_15075	COG3275	phosphorelay sensor kinase activity
FOC12_15080	COG3279	Response regulator of the LytR AlgR family
FOC12_15095	COG0628	permease
FOC12_15100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC12_15100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC12_15105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC12_15110	COG1309	transcriptional regulator
FOC12_15115	COG0463	Glycosyl transferase, family 2
FOC12_15135	COG0488	(ABC) transporter
FOC12_15150	COG1607	acyl-coa hydrolase
FOC12_15160	COG0840	transmembrane signaling receptor activity
FOC12_15185	COG0477	Major facilitator Superfamily
FOC12_15190	COG3279	Response regulator of the LytR AlgR family
FOC12_15195	COG1966	Carbon starvation protein
FOC12_15200	COG2879	small protein
FOC12_15205	COG3706	GGDEF domain
FOC12_15210	COG0351	phosphomethylpyrimidine kinase
FOC12_15220	COG2197	response regulator
FOC12_15230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC12_15235	COG1011	Hydrolase
FOC12_15255	COG0460	homoserine dehydrogenase
FOC12_15265	COG1609	Transcriptional regulator
FOC12_15270	COG2755	lipolytic protein G-D-S-L family
FOC12_15275	COG1131	(ABC) transporter
FOC12_15280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC12_15290	COG2814	Major facilitator Superfamily
FOC12_15295	COG0561	phosphatase activity
FOC12_15300	COG2233	PERMEase
FOC12_15315	COG2363	Small membrane protein
FOC12_15325	COG3773	Cell wall hydrolase
FOC12_15340	COG0280	phosphate acetyltransferase
FOC12_15345	COG0095	Lipoate-protein ligase
FOC12_15370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_15375	COG1120	ATPase activity
FOC12_15380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_15385	COG1078	dGTPase activity
FOC12_15395	COG1994	Peptidase M50
FOC12_15405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC12_15410	COG0584	glycerophosphoryl diester phosphodiesterase
FOC12_15415	COG0789	Transcriptional regulator
FOC12_15420	COG2814	Major facilitator Superfamily
FOC12_15425	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC12_15430	COG0010	Belongs to the arginase family
FOC12_15445	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC12_15450	COG4506	Protein conserved in bacteria
FOC12_15455	COG0018	arginyl-trna synthetase
FOC12_15460	COG1595	DNA-templated transcription, initiation
FOC12_15480	COG2234	aminopeptidase activity
FOC12_15490	COG0024	Methionine aminopeptidase
FOC12_15495	COG1131	(ABC) transporter
FOC12_15500	COG0842	Transport permease protein
FOC12_15505	COG4585	Histidine kinase
FOC12_15510	COG2197	response regulator
FOC12_15535	COG3300	MHYT domain
FOC12_15535	COG5001	Diguanylate cyclase
FOC12_15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC12_15550	COG2181	nitrate reductase activity
FOC12_15550	COG0247	lactate metabolic process
FOC12_15555	COG0183	Belongs to the thiolase family
FOC12_15560	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC12_15565	COG1960	acyl-CoA dehydrogenase activity
FOC12_15570	COG1960	acyl-CoA dehydrogenase activity
FOC12_15580	COG3343	RNA polymerase activity
FOC12_15590	COG4821	SIS domain
FOC12_15605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC12_15610	COG1494	fructose-1,6-bisphosphatase
FOC12_15615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC12_15630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC12_15635	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC12_15650	COG0009	L-threonylcarbamoyladenylate synthase
FOC12_15665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC12_15670	COG2259	Doxx family
FOC12_15675	COG2190	(PTS) system
FOC12_15685	COG0698	ribose 5-phosphate isomerase
FOC12_15720	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC12_15770	COG5001	Diguanylate cyclase
FOC12_15770	COG3300	MHYT domain
FOC12_15775	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC12_15785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC12_15790	COG0649	NAD binding
FOC12_15805	COG0839	Belongs to the complex I subunit 6 family
FOC12_15815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC12_15820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC12_15825	COG1007	ATP synthesis coupled electron transport
FOC12_15830	COG4836	Membrane
FOC12_15840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC12_15845	COG2385	sporulation resulting in formation of a cellular spore
FOC12_15850	COG4555	ABC transporter
FOC12_15855	COG3279	Response regulator of the LytR AlgR family
FOC12_15870	COG0739	heme binding
FOC12_15885	COG1609	Transcriptional regulator
FOC12_15930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC12_15935	COG1682	transport, permease protein
FOC12_15940	COG1134	teichoic acid transport
FOC12_15945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC12_15960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC12_15965	COG0745	RESPONSE REGULATOR receiver
FOC12_15970	COG5002	protein histidine kinase activity
FOC12_16005	COG1136	(ABC) transporter
FOC12_16010	COG0577	efflux transmembrane transporter activity
FOC12_16020	COG1191	sigma factor activity
FOC12_16050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC12_16055	COG4715	Zinc finger, swim domain protein
FOC12_16080	COG1388	LysM domain
FOC12_16080	COG3584	3D domain protein
FOC12_16085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC12_16100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_16115	COG1368	sulfuric ester hydrolase activity
FOC12_16125	COG2389	metal-binding protein
FOC12_16135	COG1620	l-lactate permease
FOC12_16145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC12_16150	COG1294	oxidase, subunit
FOC12_16155	COG1271	oxidase subunit
FOC12_16170	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC12_16175	COG0583	DNA-binding transcription factor activity
FOC12_16180	COG1511	domain protein
FOC12_16185	COG0346	lactoylglutathione lyase activity
FOC12_16195	COG1301	dicarboxylic acid transport
FOC12_16200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC12_16210	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC12_16215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC12_16220	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC12_16230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC12_16235	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC12_16240	COG1486	melibiose metabolic process
FOC12_16245	COG3394	polysaccharide catabolic process
FOC12_16260	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC12_16260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC12_16270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC12_16275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC12_16280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC12_16285	COG1316	TRANSCRIPTIONal
FOC12_16290	COG1739	Uncharacterized protein family UPF0029
FOC12_16295	COG1307	EDD domain protein, DegV family
FOC12_16300	COG1733	regulation of RNA biosynthetic process
FOC12_16305	COG0791	NLP P60 protein
FOC12_16305	COG1388	LysM domain
FOC12_16310	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC12_16315	COG1040	competence protein
FOC12_16320	COG1278	Cold shock
FOC12_16325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC12_16330	COG0653	protein targeting
FOC12_16350	COG2884	Cell division ATP-binding protein ftsE
FOC12_16355	COG2177	Part of the ABC transporter FtsEX involved in
FOC12_16360	COG0793	Belongs to the peptidase S41A family
FOC12_16360	COG3409	Peptidoglycan-binding domain 1 protein
FOC12_16365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC12_16370	COG1132	(ABC) transporter
FOC12_16385	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC12_16395	COG0583	DNA-binding transcription factor activity
FOC12_16400	COG2855	membrane
FOC12_16425	COG0789	Transcriptional regulator
FOC12_16445	COG0556	nucleotide-excision repair
FOC12_16450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC12_16460	COG1950	PFAM Membrane protein of
FOC12_16480	COG0110	maltose O-acetyltransferase activity
FOC12_16485	COG0457	Tetratricopeptide repeat
FOC12_16490	COG0492	ferredoxin-NADP+ reductase activity
FOC12_16500	COG1051	belongs to the nudix hydrolase family
FOC12_16510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC12_16520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC12_16525	COG0740	serine-type endopeptidase activity
FOC12_16530	COG2323	membrane
FOC12_16545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_16570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC12_16585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC12_16595	COG0149	triose-phosphate isomerase activity
FOC12_16600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC12_16610	COG4974	Belongs to the 'phage' integrase family
FOC12_16635	COG4695	Portal protein
FOC12_16730	COG1346	cytolysis
FOC12_16735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC12_16740	COG1647	Serine aminopeptidase, S33
FOC12_16745	COG0557	exoribonuclease II activity
FOC12_16795	COG3223	Belongs to the PsiE family
FOC12_16800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_16815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC12_16820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC12_16830	COG3290	protein histidine kinase activity
FOC12_16830	COG0840	transmembrane signaling receptor activity
FOC12_16840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC12_16845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC12_16850	COG1252	NADH dehydrogenase
FOC12_16860	COG1733	regulation of RNA biosynthetic process
FOC12_16865	COG2814	Major facilitator Superfamily
FOC12_16870	COG0656	L-ascorbic acid biosynthetic process
FOC12_16885	COG2910	NAD(P)H-binding
FOC12_16890	COG1115	amino acid carrier protein
FOC12_16895	COG1115	amino acid carrier protein
FOC12_16900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_16905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC12_16925	COG1611	Belongs to the LOG family
FOC12_16940	COG0783	Belongs to the Dps family
FOC12_16945	COG1115	amino acid carrier protein
FOC12_16950	COG0490	domain, Protein
FOC12_16955	COG0475	glutathione-regulated potassium exporter activity
FOC12_16970	COG1741	Belongs to the pirin family
FOC12_16975	COG3227	Zinc metalloprotease (Elastase)
FOC12_16980	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC12_16995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_17005	COG5002	protein histidine kinase activity
FOC12_17010	COG0745	RESPONSE REGULATOR receiver
FOC12_17015	COG1376	ErfK ybiS ycfS ynhG family protein
FOC12_17025	COG0586	Pfam SNARE associated Golgi protein
FOC12_17060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_17070	COG0706	membrane insertase activity
FOC12_17080	COG0531	amino acid
FOC12_17085	COG2814	Major facilitator Superfamily
FOC12_17100	COG0840	transmembrane signaling receptor activity
FOC12_17105	COG0011	TIGRFAM Protein of
FOC12_17120	COG1686	Belongs to the peptidase S11 family
FOC12_17130	COG1024	Enoyl-CoA hydratase
FOC12_17130	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC12_17135	COG0183	Belongs to the thiolase family
FOC12_17140	COG1960	acyl-CoA dehydrogenase activity
FOC12_17145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_17150	COG1309	transcriptional regulator
FOC12_17170	COG0039	L-malate dehydrogenase activity
FOC12_17215	COG1393	Belongs to the ArsC family
FOC12_17230	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC12_17235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC12_17245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC12_17250	COG2011	ABC-type metal ion transport system permease component
FOC12_17255	COG1464	Belongs to the NlpA lipoprotein family
FOC12_17260	COG1464	Belongs to the NlpA lipoprotein family
FOC12_17265	COG0396	ATPase activity
FOC12_17270	COG0719	Fe-S assembly protein
FOC12_17275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC12_17280	COG0822	iron-sulfur transferase activity
FOC12_17285	COG0719	Fe-S assembly protein
FOC12_17295	COG1695	Transcriptional regulator
FOC12_17300	COG0737	Belongs to the 5'-nucleotidase family
FOC12_17305	COG3377	Domain of unknown function (DUF1805)
FOC12_17315	COG0739	heme binding
FOC12_17340	COG4377	Putative membrane peptidase family (DUF2324)
FOC12_17345	COG0789	Transcriptional regulator
FOC12_17355	COG4470	Protein conserved in bacteria
FOC12_17370	COG1494	fructose-1,6-bisphosphatase
FOC12_17375	COG2445	Protein of unknown function DUF86
FOC12_17385	COG0647	UMP catabolic process
FOC12_17390	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC12_17400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC12_17405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC12_17415	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC12_17420	COG4837	Protein of unknown function (DUF1462)
FOC12_17460	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC12_17465	COG0390	transport system, permease component
FOC12_17480	COG1252	NADH dehydrogenase
FOC12_17495	COG0316	Belongs to the HesB IscA family
FOC12_17515	COG1683	Conserved Protein
FOC12_17530	COG3708	Transcriptional regulator
FOC12_17545	COG1252	NADH dehydrogenase
FOC12_17560	COG3584	3D domain protein
FOC12_17575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC12_17580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC12_17590	COG1268	BioY protein
FOC12_17600	COG2050	protein possibly involved in aromatic compounds catabolism
FOC12_17605	COG0423	glycine-tRNA ligase activity
FOC12_17620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC12_17625	COG5018	Exonuclease
FOC12_17640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC12_17650	COG2267	carboxylic ester hydrolase activity
FOC12_17655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC12_17660	COG1522	sequence-specific DNA binding
FOC12_17665	COG0436	Aminotransferase
FOC12_17670	COG1098	S1 RNA binding domain
FOC12_17675	COG2155	Conserved Protein
FOC12_17680	COG0166	Belongs to the GPI family
FOC12_17690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC12_17695	COG1285	pathogenesis
FOC12_17730	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC12_17825	COG0039	L-malate dehydrogenase activity
FOC12_17845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC12_17850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC12_17855	COG0297	glycogen (starch) synthase activity
FOC12_17860	COG0058	SHG alpha-glucan phosphorylase activity
FOC12_17875	COG1278	Cold shock
FOC12_17880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC12_17885	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC12_17890	COG1169	isochorismate synthase
FOC12_17895	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC12_17900	COG0596	Alpha beta hydrolase
FOC12_17905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC12_17915	COG4948	Mandelate Racemase Muconate Lactonizing
FOC12_17945	COG3964	amidohydrolase
FOC12_17985	COG1136	(ABC) transporter
FOC12_17990	COG0577	efflux transmembrane transporter activity
FOC12_18000	COG2205	protein histidine kinase activity
FOC12_18005	COG0745	RESPONSE REGULATOR receiver
FOC12_18010	COG3708	Transcriptional regulator
FOC12_18010	COG2207	Transcriptional regulator
FOC12_18015	COG1136	(ABC) transporter
FOC12_18020	COG0577	efflux transmembrane transporter activity
FOC12_18030	COG0586	Pfam SNARE associated Golgi protein
FOC12_18065	COG1597	lipid kinase activity
FOC12_18095	COG0745	RESPONSE REGULATOR receiver
FOC12_18100	COG5002	protein histidine kinase activity
FOC12_18135	COG1842	Phage shock protein A
FOC12_18160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_18180	COG1294	oxidase, subunit
FOC12_18185	COG1271	oxidase subunit
FOC12_18190	COG0288	reversible hydration of carbon dioxide
FOC12_18220	COG0494	nUDIX hydrolase
FOC12_18245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC12_18250	COG1116	anion transmembrane transporter activity
FOC12_18255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC12_18275	COG2267	carboxylic ester hydrolase activity
FOC12_18280	COG4191	Histidine kinase
FOC12_18285	COG5002	protein histidine kinase activity
FOC12_18290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC12_18340	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC12_18350	COG0438	transferase activity, transferring glycosyl groups
FOC12_18355	COG0671	phosphoesterase, PA-phosphatase related
FOC12_18360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC12_18365	COG2267	carboxylic ester hydrolase activity
FOC12_18385	COG1794	racemase activity, acting on amino acids and derivatives
FOC12_18395	COG1131	(ABC) transporter
FOC12_18400	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC12_18405	COG1242	4 iron, 4 sulfur cluster binding
FOC12_18425	COG1136	(ABC) transporter
FOC12_18435	COG0582	viral genome integration into host DNA
FOC12_18440	COG0490	domain, Protein
FOC12_18445	COG0475	glutathione-regulated potassium exporter activity
FOC12_18450	COG2814	Major facilitator Superfamily
FOC12_18490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC12_18500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_18525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC12_18535	COG0303	'Molybdopterin
FOC12_18540	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC12_18545	COG0314	molybdopterin synthase activity
FOC12_18560	COG4975	Glucose uptake
FOC12_18570	COG1329	Transcriptional regulator
FOC12_18590	COG3832	glyoxalase III activity
FOC12_18600	COG2814	Major facilitator Superfamily
FOC12_18605	COG2081	HI0933 family
FOC12_18610	COG2244	polysaccharide biosynthetic process
FOC12_18615	COG1187	pseudouridine synthase activity
FOC12_18620	COG1349	DNA-binding transcription factor activity
FOC12_18635	COG1523	belongs to the glycosyl hydrolase 13 family
FOC12_18640	COG0510	thiamine kinase activity
FOC12_18655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_18665	COG1363	Peptidase, m42
FOC12_18670	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC12_18675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC12_18680	COG4848	Belongs to the UPF0354 family
FOC12_18685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_18695	COG1674	ftsk spoiiie
FOC12_18710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_18730	COG2309	aminopeptidase activity
FOC12_18740	COG3118	belongs to the thioredoxin family
FOC12_18745	COG4851	CamS sex pheromone cAM373 precursor
FOC12_18750	COG1609	Transcriptional regulator
FOC12_18785	COG0666	response to abiotic stimulus
FOC12_18795	COG0745	RESPONSE REGULATOR receiver
FOC12_18805	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC12_18810	COG0517	IMP dehydrogenase activity
FOC12_18815	COG0454	-acetyltransferase
FOC12_18820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC12_18835	COG1595	DNA-templated transcription, initiation
FOC12_18845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC12_18865	COG0626	cystathionine gamma-synthase activity
FOC12_18870	COG1956	GAF domain-containing protein
FOC12_18880	COG0697	spore germination
FOC12_18885	COG0583	DNA-binding transcription factor activity
FOC12_18895	COG1104	cysteine desulfurase activity
FOC12_18910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC12_18920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC12_18925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC12_18935	COG3874	Sporulation protein YtfJ
FOC12_18940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC12_18945	COG0827	DNA restriction-modification system
FOC12_18950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC12_18970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_19010	COG0589	response to stress
FOC12_19015	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_19030	COG1476	TRANSCRIPTIONal
FOC12_19040	COG0662	Cupin 2, conserved barrel domain protein
FOC12_19045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_19080	COG0006	proline dipeptidase activity
FOC12_19095	COG4109	DRTGG domain
FOC12_19115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC12_19130	COG0587	DNA-directed DNA polymerase activity
FOC12_19135	COG0281	malic enzyme
FOC12_19140	COG1725	Transcriptional regulator
FOC12_19165	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC12_19170	COG0628	permease
FOC12_19180	COG0372	Belongs to the citrate synthase family
FOC12_19185	COG0538	isocitrate dehydrogenase activity
FOC12_19200	COG0745	RESPONSE REGULATOR receiver
FOC12_19205	COG5002	protein histidine kinase activity
FOC12_19210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC12_19210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC12_19215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC12_19220	COG1971	Probably functions as a manganese efflux pump
FOC12_19225	COG0237	dephospho-CoA kinase activity
FOC12_19230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC12_19240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC12_19250	COG3611	Membrane attachment protein
FOC12_19255	COG1484	DNA-dependent DNA replication
FOC12_19265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC12_19270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC12_19290	COG1363	Peptidase, m42
FOC12_19295	COG1309	transcriptional regulator
FOC12_19300	COG1566	PFAM secretion protein HlyD family protein
FOC12_19305	COG2814	Major facilitator Superfamily
FOC12_19330	COG1418	mRNA catabolic process
FOC12_19340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC12_19350	COG0072	phenylalanine-tRNA ligase activity
FOC12_19350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC12_19355	COG0017	Asparaginyl-tRNA synthetase
FOC12_19385	COG1286	toxin biosynthetic process
FOC12_19390	COG1796	DNA polymerase
FOC12_19390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC12_19400	COG1187	pseudouridine synthase activity
FOC12_19405	COG1114	Component of the transport system for branched-chain amino acids
FOC12_19410	COG5386	Cell surface protein
FOC12_19420	COG5386	Cell surface protein
FOC12_19435	COG1120	ATPase activity
FOC12_19440	COG4509	Sortase family
FOC12_19455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC12_19460	COG4895	conserved protein (DUF2196)
FOC12_19465	COG0745	RESPONSE REGULATOR receiver
FOC12_19470	COG2205	protein histidine kinase activity
FOC12_19475	COG1131	(ABC) transporter
FOC12_19500	COG2318	DinB family
FOC12_19520	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_19525	COG1309	transcriptional regulator
FOC12_19530	COG1024	Enoyl-CoA hydratase
FOC12_19535	COG2086	electron transfer activity
FOC12_19540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC12_19545	COG3118	belongs to the thioredoxin family
FOC12_19555	COG1719	4-vinyl reductase, 4VR
FOC12_19560	COG2009	succinate dehydrogenase
FOC12_19565	COG1053	succinate dehydrogenase
FOC12_19570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC12_19575	COG0824	Thioesterase
FOC12_19580	COG1876	peptidase activity
FOC12_19585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC12_19595	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC12_19600	COG4152	abc transporter atp-binding protein
FOC12_19605	COG1668	transmembrane transport
FOC12_19610	COG1959	2 iron, 2 sulfur cluster binding
FOC12_19620	COG0697	spore germination
FOC12_19625	COG1396	sequence-specific DNA binding
FOC12_19630	COG1983	PspC domain protein
FOC12_19645	COG3279	Response regulator of the LytR AlgR family
FOC12_19655	COG4608	Belongs to the ABC transporter superfamily
FOC12_19660	COG0444	Belongs to the ABC transporter superfamily
FOC12_19680	COG0402	S-adenosylhomocysteine deaminase activity
FOC12_19685	COG0402	S-adenosylhomocysteine deaminase activity
FOC12_19695	COG2233	PERMEase
FOC12_19700	COG2197	response regulator
FOC12_19715	COG1309	transcriptional regulator
FOC12_19735	COG5401	PFAM Sporulation and spore germination
FOC12_19745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC12_19750	COG0622	Phosphoesterase
FOC12_19795	COG0470	DNA polymerase III
FOC12_19795	COG1067	ATP-dependent peptidase activity
FOC12_19810	COG1764	response to oxidative stress
FOC12_19815	COG1846	Transcriptional regulator
FOC12_19825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC12_19835	COG1587	Uroporphyrinogen-III synthase
FOC12_19840	COG0113	porphobilinogen synthase activity
FOC12_19850	COG1388	LysM domain
FOC12_19860	COG0525	valine-tRNA ligase activity
FOC12_19865	COG0285	dihydrofolate synthase activity
FOC12_19885	COG1077	Cell shape determining protein MreB Mrl
FOC12_19890	COG1792	Involved in formation and maintenance of cell shape
FOC12_19905	COG2894	cell division
FOC12_19910	COG0739	heme binding
FOC12_19915	COG1994	Peptidase M50
FOC12_19920	COG1530	ribonuclease E activity
FOC12_19930	COG2868	ribosomal protein
FOC12_19945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC12_19950	COG0745	RESPONSE REGULATOR receiver
FOC12_19960	COG1136	(ABC) transporter
FOC12_19965	COG0577	efflux transmembrane transporter activity
FOC12_19970	COG0577	efflux transmembrane transporter activity
FOC12_19975	COG0077	Prephenate dehydratase
FOC12_19980	COG2258	MOSC domain
FOC12_19985	COG1827	regulation of RNA biosynthetic process
FOC12_19990	COG1104	cysteine desulfurase activity
FOC12_19995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC12_20000	COG0157	Belongs to the NadC ModD family
FOC12_20025	COG0640	Transcriptional regulator
FOC12_20030	COG0697	spore germination
FOC12_20035	COG0697	spore germination
FOC12_20045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC12_20075	COG1862	Preprotein translocase
FOC12_20085	COG2323	membrane
FOC12_20090	COG2244	polysaccharide biosynthetic process
FOC12_20100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC12_20100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC12_20105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC12_20110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC12_20110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC12_20120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC12_20130	COG0124	histidyl-tRNA synthetase
FOC12_20140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC12_20150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC12_20155	COG1959	2 iron, 2 sulfur cluster binding
FOC12_20160	COG1104	cysteine desulfurase activity
FOC12_20165	COG0482	sulfurtransferase activity
FOC12_20175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC12_20195	COG0628	permease
FOC12_20205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC12_20225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC12_20255	COG0768	penicillin binding
FOC12_20280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC12_20285	COG0626	cystathionine gamma-synthase activity
FOC12_20290	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_20290	COG1454	alcohol dehydrogenase
FOC12_20300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_20340	COG2259	Doxx family
FOC12_20355	COG3186	Phenylalanine-4-hydroxylase
FOC12_20395	COG2267	carboxylic ester hydrolase activity
FOC12_20405	COG1785	Belongs to the alkaline phosphatase family
FOC12_20415	COG2357	RelA SpoT domain protein
FOC12_20420	COG0778	Nitroreductase
FOC12_20430	COG1595	DNA-templated transcription, initiation
FOC12_20440	COG1191	sigma factor activity
FOC12_20455	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC12_20460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC12_20470	COG1534	Rna-binding protein
FOC12_20480	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC12_20485	COG0799	negative regulation of ribosome biogenesis
FOC12_20490	COG2226	methyltransferase
FOC12_20495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC12_20500	COG1555	photosystem II stabilization
FOC12_20500	COG1596	polysaccharide export
FOC12_20505	COG2131	deaminase
FOC12_20510	COG2333	competence protein COMEC
FOC12_20510	COG0658	competence protein
FOC12_20520	COG1466	dna polymerase III delta subunit
FOC12_20545	COG1733	regulation of RNA biosynthetic process
FOC12_20550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC12_20560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC12_20580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC12_20585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC12_20595	COG1610	YqeY-like protein
FOC12_20610	COG1702	phosphate starvation-inducible protein PhoH
FOC12_20615	COG1480	7TM receptor with intracellular HD hydrolase
FOC12_20625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC12_20630	COG0295	cytidine deaminase activity
FOC12_20635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC12_20650	COG0517	IMP dehydrogenase activity
FOC12_20660	COG0358	DNA primase activity
FOC12_20665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC12_20670	COG2010	Cytochrome c
FOC12_20675	COG2384	SAM-dependent methyltransferase
FOC12_20680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC12_20710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_20715	COG1121	(ABC) transporter
FOC12_20720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC12_20725	COG0735	belongs to the Fur family
FOC12_20750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC12_20755	COG0477	Major facilitator Superfamily
FOC12_20765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC12_20770	COG0573	inorganic phosphate transmembrane transporter activity
FOC12_20775	COG0581	inorganic phosphate transmembrane transporter activity
FOC12_20780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC12_20785	COG0704	Plays a role in the regulation of phosphate uptake
FOC12_20790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC12_20800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC12_20805	COG4483	Protein conserved in bacteria
FOC12_20810	COG1940	carbohydrate kinase activity
FOC12_20820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_20840	COG0626	cystathionine gamma-synthase activity
FOC12_20845	COG0626	cystathionine gamma-synthase activity
FOC12_20850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC12_20850	COG0646	methionine synthase
FOC12_20855	COG0646	methionine synthase
FOC12_20855	COG1410	methionine synthase
FOC12_20860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC12_20910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC12_20915	COG1459	type II secretion system
FOC12_20925	COG4970	Tfp pilus assembly protein FimT
FOC12_20980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC12_21010	COG1725	Transcriptional regulator
FOC12_21015	COG1131	(ABC) transporter
FOC12_21050	COG2076	Multidrug Resistance protein
FOC12_21055	COG2076	Multidrug Resistance protein
FOC12_21065	COG1609	Transcriptional regulator
FOC12_21070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC12_21075	COG0095	Lipoate-protein ligase
FOC12_21095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC12_21105	COG3872	metal-dependent enzyme
FOC12_21120	COG0006	proline dipeptidase activity
FOC12_21145	COG3854	ATPases associated with a variety of cellular activities
FOC12_21190	COG0511	ligase activity, forming carbon-carbon bonds
FOC12_21195	COG0439	Biotin carboxylase
FOC12_21200	COG1302	Protein conserved in bacteria
FOC12_21225	COG0142	geranyltranstransferase activity
FOC12_21235	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC12_21245	COG0497	DNA recombination
FOC12_21250	COG0750	zinc metalloprotease
FOC12_21255	COG0745	RESPONSE REGULATOR receiver
FOC12_21265	COG3093	addiction module antidote protein HigA
FOC12_21270	COG0584	glycerophosphoryl diester phosphodiesterase
FOC12_21280	COG3829	transcription factor binding
FOC12_21280	COG3290	protein histidine kinase activity
FOC12_21285	COG0280	phosphate acetyltransferase
FOC12_21290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC12_21300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC12_21305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC12_21310	COG0022	dehydrogenase e1 component
FOC12_21315	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC12_21320	COG0772	Belongs to the SEDS family
FOC12_21340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC12_21345	COG0765	amino acid transport
FOC12_21350	COG1126	abc transporter atp-binding protein
FOC12_21355	COG4129	membrane
FOC12_21360	COG1376	ErfK ybiS ycfS ynhG family protein
FOC12_21375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC12_21380	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC12_21390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC12_21410	COG1760	l-serine dehydratase
FOC12_21415	COG1760	l-serine dehydratase
FOC12_21420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC12_21430	COG0300	oxidoreductase activity
FOC12_21445	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC12_21455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC12_21475	COG1522	sequence-specific DNA binding
FOC12_21485	COG0737	Belongs to the 5'-nucleotidase family
FOC12_21500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC12_21510	COG0156	8-amino-7-oxononanoate synthase activity
FOC12_21515	COG2226	methyltransferase
FOC12_21515	COG1073	alpha beta
FOC12_21520	COG4106	trans-aconitate 2-methyltransferase activity
FOC12_21525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC12_21545	COG0307	riboflavin synthase, alpha
FOC12_21550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC12_21550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC12_21565	COG1073	alpha beta
FOC12_21570	COG0456	acetyltransferase
FOC12_21575	COG1609	Transcriptional regulator
FOC12_21580	COG2056	Na+-H+ antiporter family
FOC12_21585	COG0596	Alpha beta hydrolase
FOC12_21595	COG1525	nuclease
FOC12_21595	COG0737	Belongs to the 5'-nucleotidase family
FOC12_21595	COG4085	toxin activity
FOC12_21605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC12_21605	COG0456	acetyltransferase
FOC12_21610	COG0656	L-ascorbic acid biosynthetic process
FOC12_21615	COG0667	Aldo Keto reductase
FOC12_21635	COG1300	Membrane
FOC12_21640	COG0735	belongs to the Fur family
FOC12_21650	COG4974	Belongs to the 'phage' integrase family
FOC12_21675	COG0598	Magnesium transport protein CorA
FOC12_21690	COG1846	Transcriptional regulator
FOC12_21705	COG1131	(ABC) transporter
FOC12_21710	COG1725	Transcriptional regulator
FOC12_21715	COG1686	Belongs to the peptidase S11 family
FOC12_21735	COG0733	neurotransmitter:sodium symporter activity
FOC12_21760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_21775	COG0697	spore germination
FOC12_21780	COG0561	phosphatase activity
FOC12_21785	COG4086	secreted protein
FOC12_21790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC12_21795	COG0456	acetyltransferase
FOC12_21800	COG1547	Domain of unknown function (DUF309)
FOC12_21825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC12_21845	COG3711	transcriptional antiterminator
FOC12_21850	COG2190	(PTS) system
FOC12_21850	COG1263	PTS System
FOC12_21850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC12_21875	COG0778	Nitroreductase
FOC12_21880	COG3706	GGDEF domain
FOC12_21900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC12_21920	COG0436	Aminotransferase
FOC12_21925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC12_21945	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_21950	COG1695	Transcriptional regulator
FOC12_21990	COG0183	Belongs to the thiolase family
FOC12_22030	COG3842	ATPase activity
FOC12_22035	COG0366	Alpha amylase catalytic
FOC12_22045	COG2182	Extracellular solute-binding protein
FOC12_22050	COG1175	transmembrane transport
FOC12_22055	COG3833	ABC-type maltose transport systems, permease component
FOC12_22060	COG1609	Transcriptional regulator
FOC12_22065	COG0436	Aminotransferase
FOC12_22075	COG2205	protein histidine kinase activity
FOC12_22085	COG3209	COG3209 Rhs family protein
FOC12_22105	COG2814	Major facilitator Superfamily
FOC12_22140	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC12_22150	COG1408	metallophosphoesterase
FOC12_22155	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_22160	COG2200	EAL domain
FOC12_22175	COG4703	Protein of unknown function (DUF1797)
FOC12_22180	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC12_22190	COG0517	IMP dehydrogenase activity
FOC12_22195	COG0583	DNA-binding transcription factor activity
FOC12_22215	COG0569	domain protein
FOC12_22220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC12_22235	COG0242	peptide deformylase activity
FOC12_22245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC12_22250	COG0022	dehydrogenase e1 component
FOC12_22255	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC12_22300	COG1982	Orn Lys Arg decarboxylase major
FOC12_22320	COG0483	inositol monophosphate 1-phosphatase activity
FOC12_22345	COG4896	Protein conserved in bacteria
FOC12_22355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC12_22360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC12_22365	COG4838	Belongs to the UPF0358 family
FOC12_22370	COG0772	Belongs to the SEDS family
FOC12_22375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC12_22410	COG3336	cytochrome c oxidase
FOC12_22425	COG2340	Cysteine-rich secretory protein family
FOC12_22440	COG0406	alpha-ribazole phosphatase activity
FOC12_22445	COG3679	Belongs to the UPF0342 family
FOC12_22460	COG0742	ribosomal rna small subunit methyltransferase
FOC12_22470	COG3314	Sporulation integral membrane protein YlbJ
FOC12_22475	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC12_22480	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC12_22490	COG0582	viral genome integration into host DNA
FOC12_22500	COG1396	sequence-specific DNA binding
FOC12_22510	COG1396	sequence-specific DNA binding
FOC12_22530	COG1484	DNA-dependent DNA replication
FOC12_22555	COG1191	sigma factor activity
FOC12_22630	COG0582	viral genome integration into host DNA
FOC12_22655	COG4626	Terminase
FOC12_22655	COG1802	Transcriptional regulator
FOC12_22745	COG4824	toxin secretion phage lysis holin
FOC12_22795	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC12_22820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC12_22835	COG4839	cell division protein FtsL
FOC12_22845	COG0768	penicillin binding
FOC12_22850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC12_22865	COG0772	Belongs to the SEDS family
FOC12_22870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC12_22875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC12_22880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC12_22885	COG0849	cell division
FOC12_22890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC12_22900	COG1191	sigma factor activity
FOC12_22905	COG1191	sigma factor activity
FOC12_22910	COG1873	PFAM PRC-barrel domain
FOC12_22920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC12_22930	COG0762	integral membrane protein
FOC12_22935	COG2302	S4 RNA-binding domain
FOC12_22940	COG3599	regulation of cell shape
FOC12_22960	COG0564	pseudouridine synthase activity
FOC12_22985	COG0505	Belongs to the CarA family
FOC12_23025	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC12_23040	COG0006	proline dipeptidase activity
FOC12_23050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC12_23055	COG1561	YicC-like family, N-terminal region
FOC12_23065	COG0194	GDP metabolic process
FOC12_23075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC12_23080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC12_23085	COG0242	peptide deformylase activity
FOC12_23095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC12_23095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC12_23105	COG0631	protein serine/threonine phosphatase activity
FOC12_23110	COG0515	serine threonine protein kinase
FOC12_23110	COG2815	serine threonine protein kinase
FOC12_23115	COG1162	GTPase activity
FOC12_23120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC12_23125	COG1564	THIamine pyrophosphokinase
FOC12_23140	COG1302	Protein conserved in bacteria
FOC12_23145	COG1461	Dihydroxyacetone kinase
FOC12_23150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC12_23165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC12_23170	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_23185	COG1196	nuclear chromosome segregation
FOC12_23190	COG0552	protein localization to endoplasmic reticulum
FOC12_23200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC12_23210	COG1837	Belongs to the UPF0109 family
FOC12_23250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC12_23260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC12_23270	COG4974	Belongs to the 'phage' integrase family
FOC12_23300	COG0528	UMP kinase activity
FOC12_23310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC12_23315	COG4589	Belongs to the CDS family
FOC12_23320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC12_23325	COG0750	zinc metalloprotease
FOC12_23345	COG0195	Participates in both transcription termination and antitermination
FOC12_23350	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC12_23355	COG1358	cellular component organization or biogenesis
FOC12_23365	COG1550	Protein conserved in bacteria
FOC12_23375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC12_23380	COG0196	riboflavin kinase activity
FOC12_23395	COG0726	polysaccharide deacetylase
FOC12_23400	COG0612	Peptidase, M16
FOC12_23405	COG1873	PFAM PRC-barrel domain
FOC12_23410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC12_23415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC12_23420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC12_23425	COG0527	aspartate kinase activity
FOC12_23435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC12_23440	COG0740	serine-type endopeptidase activity
FOC12_23450	COG1674	ftsk spoiiie
FOC12_23455	COG2188	Transcriptional regulator
FOC12_23480	COG0612	Peptidase, M16
FOC12_23485	COG0612	Peptidase, M16
FOC12_23490	COG0300	oxidoreductase activity
FOC12_23505	COG1426	Protein conserved in bacteria
FOC12_23510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC12_23535	COG1692	metallophosphoesterase
FOC12_23540	COG2359	stage V sporulation protein S
FOC12_23550	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC12_23550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC12_23555	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC12_23560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC12_23565	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC12_23610	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC12_23620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC12_23625	COG1368	sulfuric ester hydrolase activity
FOC12_23630	COG0562	UDP-galactopyranose mutase
FOC12_23635	COG3773	Cell wall hydrolase
FOC12_23640	COG1404	Belongs to the peptidase S8 family
FOC12_23660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC12_23665	COG0596	Alpha beta hydrolase
FOC12_23665	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC12_23670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC12_23675	COG1380	Effector of murein hydrolase LrgA
FOC12_23680	COG1346	cytolysis
FOC12_23700	COG3300	MHYT domain
FOC12_23700	COG5001	Diguanylate cyclase
FOC12_23705	COG0346	lactoylglutathione lyase activity
FOC12_23710	COG2267	carboxylic ester hydrolase activity
FOC12_23725	COG2364	Membrane
FOC12_23735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC12_23740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC12_23745	COG2169	Transcriptional regulator
FOC12_23750	COG0708	Exodeoxyribonuclease III
FOC12_23760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_23765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_23770	COG1120	ATPase activity
FOC12_23775	COG2819	hydrolase of the alpha beta superfamily
FOC12_23785	COG1937	Protein conserved in bacteria
FOC12_23790	COG2608	mercury ion transmembrane transporter activity
FOC12_23795	COG2217	Heavy metal translocating P-type atpase
FOC12_23805	COG2116	formate transmembrane transporter activity
FOC12_23810	COG1408	metallophosphoesterase
FOC12_23820	COG1113	amino acid transport
FOC12_23830	COG2322	membrane
FOC12_23840	COG1349	DNA-binding transcription factor activity
FOC12_23845	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC12_23850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC12_23850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC12_23850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC12_23855	COG3584	3D domain protein
FOC12_23855	COG1388	LysM domain
FOC12_23885	COG0464	growth
FOC12_23895	COG2860	membrane
FOC12_23905	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC12_23910	COG0789	Transcriptional regulator
FOC12_23915	COG0174	glutamine synthetase
FOC12_23935	COG1396	sequence-specific DNA binding
FOC12_24015	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC12_24050	COG1595	DNA-templated transcription, initiation
FOC12_24195	COG4824	toxin secretion phage lysis holin
FOC12_24200	COG3409	Peptidoglycan-binding domain 1 protein
FOC12_24200	COG1388	LysM domain
FOC12_24200	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC12_24230	COG1695	Transcriptional regulator
FOC12_24250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC12_24270	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC12_24275	COG3639	organic phosphonate transmembrane transporter activity
FOC12_24305	COG1132	(ABC) transporter
FOC12_24310	COG1132	(ABC) transporter
FOC12_24325	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC12_24325	COG3409	Peptidoglycan-binding domain 1 protein
FOC12_24350	COG1346	cytolysis
FOC12_24355	COG1380	Effector of murein hydrolase LrgA
FOC12_24360	COG0583	DNA-binding transcription factor activity
FOC12_24370	COG0785	Cytochrome C biogenesis protein
FOC12_24375	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC12_24425	COG2226	methyltransferase
FOC12_24450	COG0010	Belongs to the arginase family
FOC12_24455	COG1329	Transcriptional regulator
FOC12_24460	COG1902	pentaerythritol trinitrate reductase activity
FOC12_24465	COG0069	glutamate synthase activity
FOC12_24470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC12_24475	COG0346	lactoylglutathione lyase activity
FOC12_24480	COG0400	carboxylic ester hydrolase activity
FOC12_24485	COG5002	protein histidine kinase activity
FOC12_24495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_24545	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_24550	COG1268	BioY protein
FOC12_24555	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_24560	COG0183	Belongs to the thiolase family
FOC12_24575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC12_24605	COG0726	polysaccharide deacetylase
FOC12_24615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC12_24620	COG2274	protein secretion by the type I secretion system
FOC12_24630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC12_24660	COG0824	Thioesterase
FOC12_24665	COG4841	protein insertion into membrane
FOC12_24670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC12_24685	COG0745	RESPONSE REGULATOR receiver
FOC12_24690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC12_24695	COG1832	CoA-binding protein
FOC12_24700	COG0187	DNA topoisomerase II activity
FOC12_24705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC12_24710	COG0673	inositol 2-dehydrogenase activity
FOC12_24720	COG1131	(ABC) transporter
FOC12_24735	COG1595	DNA-templated transcription, initiation
FOC12_24745	COG1316	TRANSCRIPTIONal
FOC12_24755	COG4166	transmembrane transport
FOC12_24760	COG4166	transmembrane transport
FOC12_24765	COG4166	transmembrane transport
FOC12_24770	COG2226	methyltransferase
FOC12_24810	COG0697	spore germination
FOC12_24815	COG3383	formate dehydrogenase (NAD+) activity
FOC12_24820	COG2427	Protein of unknown function (DUF1641)
FOC12_24825	COG5609	conserved protein (DUF2294)
FOC12_24830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC12_24840	COG2116	formate transmembrane transporter activity
FOC12_24845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC12_24850	COG0303	'Molybdopterin
FOC12_24855	COG0314	molybdopterin synthase activity
FOC12_24865	COG0489	protein tyrosine kinase activity
FOC12_24880	COG3326	Membrane
FOC12_24885	COG2962	Rard protein
FOC12_24890	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC12_24895	COG1657	PFAM Prenyltransferase squalene oxidase
FOC12_24905	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_24910	COG1012	belongs to the aldehyde dehydrogenase family
FOC12_24920	COG4145	pantothenate transmembrane transporter activity
FOC12_24935	COG0165	Argininosuccinate lyase
FOC12_24945	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_24975	COG0716	FMN binding
FOC12_24985	COG1278	Cold shock
FOC12_25010	COG2720	vancomycin resistance protein
FOC12_25015	COG2514	catechol 2,3-dioxygenase activity
FOC12_25030	COG1285	pathogenesis
FOC12_25040	COG1024	Enoyl-CoA hydratase
FOC12_25045	COG1216	Glycosyl transferase, family 2
FOC12_25075	COG0277	FAD linked oxidase domain protein
FOC12_25080	COG0385	Bile acid
FOC12_25090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC12_25095	COG2808	Putative FMN-binding domain
FOC12_25115	COG0604	alcohol dehydrogenase
FOC12_25120	COG0640	Transcriptional regulator
FOC12_25145	COG0584	glycerophosphoryl diester phosphodiesterase
FOC12_25175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC12_25180	COG1164	Oligoendopeptidase f
FOC12_25200	COG1193	negative regulation of DNA recombination
FOC12_25220	COG0583	DNA-binding transcription factor activity
FOC12_25250	COG0384	phenazine biosynthesis protein PhzF
FOC12_25255	COG3739	integral membrane protein
FOC12_25260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_25265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC12_25270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_25290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC12_25295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC12_25325	COG2814	Major facilitator Superfamily
FOC12_25330	COG1113	amino acid transport
FOC12_25370	COG2072	flavoprotein involved in K transport
FOC12_25405	COG3409	Peptidoglycan-binding domain 1 protein
FOC12_25405	COG3757	hydrolase, family 25
FOC12_25410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_25420	COG1151	hydroxylamine reductase activity
FOC12_25445	COG3152	Membrane
FOC12_25465	COG1309	transcriptional regulator
FOC12_25480	COG1191	sigma factor activity
FOC12_25515	COG1733	regulation of RNA biosynthetic process
FOC12_25525	COG0318	PFAM AMP-dependent synthetase and ligase
FOC12_25535	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_25545	COG0384	phenazine biosynthesis protein PhzF
FOC12_25565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_25580	COG1733	regulation of RNA biosynthetic process
FOC12_25585	COG1733	regulation of RNA biosynthetic process
FOC12_25590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC12_25600	COG2188	Transcriptional regulator
FOC12_25605	COG1733	regulation of RNA biosynthetic process
FOC12_25610	COG1393	Belongs to the ArsC family
FOC12_25635	COG0814	amino acid
FOC12_25640	COG0346	lactoylglutathione lyase activity
FOC12_25655	COG2814	Major facilitator Superfamily
FOC12_25660	COG0656	L-ascorbic acid biosynthetic process
FOC12_25685	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_25700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC12_25705	COG0604	alcohol dehydrogenase
FOC12_25710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC12_25715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC12_25725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC12_25730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC12_25740	COG1070	Carbohydrate kinase
FOC12_25745	COG2706	6-phosphogluconolactonase activity
FOC12_25750	COG3813	Protein conserved in bacteria
FOC12_25755	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC12_25760	COG0697	spore germination
FOC12_25765	COG0789	Transcriptional regulator
FOC12_25770	COG1253	flavin adenine dinucleotide binding
FOC12_25800	COG0477	Major facilitator Superfamily
FOC12_25810	COG2226	methyltransferase
FOC12_25825	COG0628	permease
FOC12_25830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC12_25835	COG0180	Tryptophanyl-tRNA synthetase
FOC12_25840	COG1136	(ABC) transporter
FOC12_25850	COG0110	maltose O-acetyltransferase activity
FOC12_25855	COG0738	Major facilitator superfamily
FOC12_25860	COG1940	carbohydrate kinase activity
FOC12_25865	COG0346	lactoylglutathione lyase activity
FOC12_25900	COG1011	Hydrolase
FOC12_25925	COG1131	(ABC) transporter
FOC12_25935	COG1028	Short-chain dehydrogenase reductase Sdr
FOC12_25955	COG0778	Nitroreductase
FOC12_25960	COG1733	regulation of RNA biosynthetic process
FOC12_25975	COG0124	histidyl-tRNA synthetase
FOC12_25980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC12_25985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC12_25990	COG3620	sequence-specific DNA binding
FOC12_26005	COG2356	endonuclease I
FOC12_26010	COG1288	antiporter activity
FOC12_26015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC12_26030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC12_26035	COG1122	ATPase activity
FOC12_26065	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC12_26075	COG2031	fatty acid transporter
FOC12_26085	COG1309	transcriptional regulator
FOC12_26090	COG2076	Multidrug Resistance protein
FOC12_26110	COG1131	(ABC) transporter
FOC12_26115	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC12_26130	COG2814	Major facilitator Superfamily
FOC12_26135	COG1846	Transcriptional regulator
FOC12_26145	COG0477	Major facilitator Superfamily
FOC12_26195	COG2207	Transcriptional regulator
FOC12_26195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC12_26200	COG0662	Cupin 2, conserved barrel domain protein
FOC12_26215	COG1595	DNA-templated transcription, initiation
FOC12_26235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC12_26250	COG0531	amino acid
FOC12_26255	COG1522	sequence-specific DNA binding
FOC12_26260	COG1335	isochorismatase
FOC12_26270	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC12_26275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC12_26285	COG1760	l-serine dehydratase
FOC12_26290	COG1760	l-serine dehydratase
FOC12_26295	COG0814	amino acid
FOC12_26310	COG1309	transcriptional regulator
FOC12_26315	COG2814	Major facilitator Superfamily
FOC12_26335	COG0534	Mate efflux family protein
FOC12_26365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC12_26380	COG0457	Tetratricopeptide repeat
FOC12_26385	COG1609	Transcriptional regulator
FOC12_26395	COG0561	phosphatase activity
FOC12_26400	COG0673	inositol 2-dehydrogenase activity
FOC12_26405	COG0738	Major facilitator superfamily
FOC12_26425	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC12_26435	COG0583	DNA-binding transcription factor activity
FOC12_26445	COG1139	Iron-sulfur cluster binding protein
FOC12_26450	COG1556	Lactate utilization protein
FOC12_26455	COG2271	Major facilitator Superfamily
FOC12_26460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC12_26465	COG2808	Putative FMN-binding domain
FOC12_26475	COG1846	Transcriptional regulator
FOC12_26480	COG2364	Membrane
FOC12_26490	COG5002	protein histidine kinase activity
FOC12_26490	COG3850	Histidine kinase
FOC12_26505	COG0577	efflux transmembrane transporter activity
FOC12_26510	COG1136	(ABC) transporter
FOC12_26525	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC12_26530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC12_26540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC12_26545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC12_26560	COG1476	TRANSCRIPTIONal
FOC12_26580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC12_26605	COG3850	Histidine kinase
FOC12_26605	COG5002	protein histidine kinase activity
FOC12_26610	COG0745	RESPONSE REGULATOR receiver
FOC12_26635	COG2814	Major facilitator Superfamily
FOC12_26675	COG2169	Transcriptional regulator
FOC12_26700	COG0346	lactoylglutathione lyase activity
FOC12_26715	COG1522	sequence-specific DNA binding
FOC12_26730	COG0443	Heat shock 70 kDa protein
FOC12_26745	COG0640	Transcriptional regulator
FOC12_26750	COG0346	lactoylglutathione lyase activity
FOC12_26755	COG0798	PFAM Bile acid sodium symporter
FOC12_26785	COG1121	(ABC) transporter
FOC12_26790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC12_26795	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC12_26800	COG2267	carboxylic ester hydrolase activity
FOC12_26805	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC12_26820	COG5609	conserved protein (DUF2294)
FOC12_26825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC12_26835	COG0288	reversible hydration of carbon dioxide
FOC12_26840	COG0415	Belongs to the DNA photolyase family
FOC12_26880	COG1846	Transcriptional regulator
FOC12_26885	COG0583	DNA-binding transcription factor activity
FOC12_26905	COG1335	isochorismatase
FOC12_26910	COG2267	carboxylic ester hydrolase activity
FOC12_26915	COG0753	catalase activity
FOC12_26920	COG0737	Belongs to the 5'-nucleotidase family
FOC12_26955	COG2066	Belongs to the glutaminase family
FOC12_26965	COG0784	Response regulator, receiver
FOC12_26990	COG0281	malic enzyme
FOC12_27000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC12_27005	COG1114	Component of the transport system for branched-chain amino acids
FOC12_27010	COG0531	amino acid
FOC12_27015	COG0322	excinuclease ABC activity
FOC12_27025	COG1396	sequence-specific DNA binding
FOC12_27030	COG0252	asparaginase activity
FOC12_27035	COG1027	Aspartate ammonia-lyase
FOC12_27050	COG1063	alcohol dehydrogenase
FOC12_27080	COG1280	lysine exporter protein (LysE YggA)