locus-tag	class	description
C3496_00010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3496_00015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3496_00015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3496_00025	COG2244	polysaccharide biosynthetic process
C3496_00030	COG2323	membrane
C3496_00040	COG1862	Preprotein translocase
C3496_00070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C3496_00080	COG0697	spore germination
C3496_00085	COG0640	Transcriptional regulator
C3496_00110	COG0157	Belongs to the NadC ModD family
C3496_00115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C3496_00120	COG1104	cysteine desulfurase activity
C3496_00125	COG1827	regulation of RNA biosynthetic process
C3496_00130	COG2258	MOSC domain
C3496_00135	COG0077	Prephenate dehydratase
C3496_00140	COG0577	efflux transmembrane transporter activity
C3496_00145	COG0577	efflux transmembrane transporter activity
C3496_00150	COG1136	(ABC) transporter
C3496_00155	COG5002	protein histidine kinase activity
C3496_00160	COG0745	RESPONSE REGULATOR receiver
C3496_00170	COG3290	protein histidine kinase activity
C3496_00180	COG2868	ribosomal protein
C3496_00190	COG1530	ribonuclease E activity
C3496_00195	COG1994	Peptidase M50
C3496_00200	COG0739	heme binding
C3496_00205	COG2894	cell division
C3496_00225	COG1077	Cell shape determining protein MreB Mrl
C3496_00250	COG0285	dihydrofolate synthase activity
C3496_00255	COG0525	valine-tRNA ligase activity
C3496_00265	COG1388	LysM domain
C3496_00275	COG0113	porphobilinogen synthase activity
C3496_00280	COG1587	Uroporphyrinogen-III synthase
C3496_00290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3496_00300	COG1846	Transcriptional regulator
C3496_00305	COG1764	response to oxidative stress
C3496_00320	COG1067	ATP-dependent peptidase activity
C3496_00320	COG0470	DNA polymerase III
C3496_00370	COG0622	Phosphoesterase
C3496_00385	COG5401	PFAM Sporulation and spore germination
C3496_00405	COG1309	transcriptional regulator
C3496_00420	COG2197	response regulator
C3496_00455	COG0640	Transcriptional regulator
C3496_00465	COG0798	PFAM Bile acid sodium symporter
C3496_00480	COG0803	Belongs to the bacterial solute-binding protein 9 family
C3496_00485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3496_00490	COG1121	(ABC) transporter
C3496_00505	COG1999	signal sequence binding
C3496_00510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3496_00515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3496_00545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C3496_00545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3496_00560	COG2197	response regulator
C3496_00565	COG2233	PERMEase
C3496_00570	COG0402	S-adenosylhomocysteine deaminase activity
C3496_00580	COG1396	sequence-specific DNA binding
C3496_00585	COG0697	spore germination
C3496_00595	COG1959	2 iron, 2 sulfur cluster binding
C3496_00600	COG1668	transmembrane transport
C3496_00605	COG4152	abc transporter atp-binding protein
C3496_00610	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C3496_00615	COG1360	Flagellar Motor Protein
C3496_00620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3496_00625	COG1876	peptidase activity
C3496_00630	COG0824	Thioesterase
C3496_00635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3496_00640	COG1053	succinate dehydrogenase
C3496_00645	COG2009	succinate dehydrogenase
C3496_00650	COG1719	4-vinyl reductase, 4VR
C3496_00660	COG3118	belongs to the thioredoxin family
C3496_00665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C3496_00670	COG2086	electron transfer activity
C3496_00675	COG1024	Enoyl-CoA hydratase
C3496_00680	COG1309	transcriptional regulator
C3496_00685	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_00695	COG2318	DinB family
C3496_00720	COG1131	(ABC) transporter
C3496_00725	COG2205	protein histidine kinase activity
C3496_00730	COG0745	RESPONSE REGULATOR receiver
C3496_00740	COG4895	conserved protein (DUF2196)
C3496_00745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C3496_00760	COG4509	Sortase family
C3496_00765	COG1120	ATPase activity
C3496_00780	COG5386	Cell surface protein
C3496_00785	COG5386	Cell surface protein
C3496_00790	COG1114	Component of the transport system for branched-chain amino acids
C3496_00795	COG1187	pseudouridine synthase activity
C3496_00810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3496_00810	COG1796	DNA polymerase
C3496_00815	COG1286	toxin biosynthetic process
C3496_00865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3496_00875	COG1418	mRNA catabolic process
C3496_00885	COG2814	Major facilitator Superfamily
C3496_00890	COG1566	PFAM secretion protein HlyD family protein
C3496_00895	COG1309	transcriptional regulator
C3496_00900	COG1363	Peptidase, m42
C3496_00925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3496_00935	COG1484	DNA-dependent DNA replication
C3496_00940	COG3611	Membrane attachment protein
C3496_00950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C3496_00960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3496_00965	COG0237	dephospho-CoA kinase activity
C3496_00970	COG1971	Probably functions as a manganese efflux pump
C3496_00980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_00980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_00985	COG5002	protein histidine kinase activity
C3496_00990	COG0745	RESPONSE REGULATOR receiver
C3496_01015	COG0538	isocitrate dehydrogenase activity
C3496_01020	COG0372	Belongs to the citrate synthase family
C3496_01035	COG0628	permease
C3496_01040	COG3030	protein affecting phage T7 exclusion by the F plasmid
C3496_01065	COG1725	Transcriptional regulator
C3496_01070	COG0281	malic enzyme
C3496_01075	COG0587	DNA-directed DNA polymerase activity
C3496_01090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C3496_01115	COG4109	DRTGG domain
C3496_01130	COG0006	proline dipeptidase activity
C3496_01175	COG0662	Cupin 2, conserved barrel domain protein
C3496_01185	COG1476	TRANSCRIPTIONal
C3496_01200	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_01205	COG0589	response to stress
C3496_01260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_01275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C3496_01280	COG0827	DNA restriction-modification system
C3496_01285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C3496_01290	COG3874	Sporulation protein YtfJ
C3496_01305	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C3496_01315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_01330	COG1104	cysteine desulfurase activity
C3496_01340	COG0583	DNA-binding transcription factor activity
C3496_01345	COG0697	spore germination
C3496_01350	COG1309	transcriptional regulator
C3496_01355	COG1956	GAF domain-containing protein
C3496_01360	COG0626	cystathionine gamma-synthase activity
C3496_01395	COG1595	DNA-templated transcription, initiation
C3496_01405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_01410	COG0454	-acetyltransferase
C3496_01415	COG0517	IMP dehydrogenase activity
C3496_01420	COG0123	including yeast histone deacetylase and acetoin utilization protein
C3496_01435	COG0745	RESPONSE REGULATOR receiver
C3496_01445	COG0666	response to abiotic stimulus
C3496_01480	COG1609	Transcriptional regulator
C3496_01495	COG4851	CamS sex pheromone cAM373 precursor
C3496_01500	COG3118	belongs to the thioredoxin family
C3496_01510	COG2309	aminopeptidase activity
C3496_01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_01555	COG1674	ftsk spoiiie
C3496_01570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_01585	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C3496_01590	COG1363	Peptidase, m42
C3496_01600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_01615	COG0510	thiamine kinase activity
C3496_01620	COG1523	belongs to the glycosyl hydrolase 13 family
C3496_01635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_01640	COG1349	DNA-binding transcription factor activity
C3496_01645	COG1187	pseudouridine synthase activity
C3496_01650	COG2244	polysaccharide biosynthetic process
C3496_01655	COG2081	HI0933 family
C3496_01660	COG2814	Major facilitator Superfamily
C3496_01670	COG3832	glyoxalase III activity
C3496_01695	COG1329	Transcriptional regulator
C3496_01720	COG0314	molybdopterin synthase activity
C3496_01735	COG1763	Mo-molybdopterin cofactor biosynthetic process
C3496_01740	COG0303	'Molybdopterin
C3496_01750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_01755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3496_01775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_01785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3496_01825	COG2814	Major facilitator Superfamily
C3496_01830	COG0475	glutathione-regulated potassium exporter activity
C3496_01835	COG0490	domain, Protein
C3496_01840	COG0582	viral genome integration into host DNA
C3496_01850	COG1136	(ABC) transporter
C3496_01870	COG1242	4 iron, 4 sulfur cluster binding
C3496_01875	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C3496_01890	COG1794	racemase activity, acting on amino acids and derivatives
C3496_01915	COG2267	carboxylic ester hydrolase activity
C3496_01920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3496_01925	COG0671	phosphoesterase, PA-phosphatase related
C3496_01930	COG0438	transferase activity, transferring glycosyl groups
C3496_01940	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3496_01955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_02005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3496_02010	COG5002	protein histidine kinase activity
C3496_02015	COG4191	Histidine kinase
C3496_02020	COG2267	carboxylic ester hydrolase activity
C3496_02045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_02050	COG1116	anion transmembrane transporter activity
C3496_02055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_02075	COG0494	nUDIX hydrolase
C3496_02105	COG0288	reversible hydration of carbon dioxide
C3496_02110	COG1271	oxidase subunit
C3496_02115	COG1294	oxidase, subunit
C3496_02140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_02165	COG1842	Phage shock protein A
C3496_02210	COG5002	protein histidine kinase activity
C3496_02215	COG0745	RESPONSE REGULATOR receiver
C3496_02240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3496_02245	COG1597	lipid kinase activity
C3496_02260	COG0577	efflux transmembrane transporter activity
C3496_02265	COG1136	(ABC) transporter
C3496_02290	COG0586	Pfam SNARE associated Golgi protein
C3496_02300	COG4977	sequence-specific DNA binding
C3496_02310	COG0577	efflux transmembrane transporter activity
C3496_02315	COG1136	(ABC) transporter
C3496_02320	COG3708	Transcriptional regulator
C3496_02320	COG2207	Transcriptional regulator
C3496_02330	COG1131	(ABC) transporter
C3496_02335	COG5658	integral membrane protein
C3496_02340	COG0640	Transcriptional regulator
C3496_02345	COG0745	RESPONSE REGULATOR receiver
C3496_02350	COG2205	protein histidine kinase activity
C3496_02355	COG0577	efflux transmembrane transporter activity
C3496_02360	COG0577	efflux transmembrane transporter activity
C3496_02365	COG1136	(ABC) transporter
C3496_02370	COG0577	efflux transmembrane transporter activity
C3496_02385	COG2188	Transcriptional regulator
C3496_02405	COG3964	amidohydrolase
C3496_02425	COG4948	Mandelate Racemase Muconate Lactonizing
C3496_02440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C3496_02445	COG0596	Alpha beta hydrolase
C3496_02455	COG1169	isochorismate synthase
C3496_02460	COG1575	Belongs to the MenA family. Type 1 subfamily
C3496_02465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3496_02490	COG0058	SHG alpha-glucan phosphorylase activity
C3496_02500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C3496_02635	COG0544	peptidyl-prolyl cis-trans isomerase activity
C3496_02675	COG1285	pathogenesis
C3496_02680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3496_02700	COG2155	Conserved Protein
C3496_02705	COG1098	S1 RNA binding domain
C3496_02710	COG0436	Aminotransferase
C3496_02715	COG1522	sequence-specific DNA binding
C3496_02720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3496_02725	COG2267	carboxylic ester hydrolase activity
C3496_02735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C3496_02750	COG5018	Exonuclease
C3496_02755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_02780	COG2050	protein possibly involved in aromatic compounds catabolism
C3496_02790	COG1268	BioY protein
C3496_02800	COG0297	glycogen (starch) synthase activity
C3496_02820	COG4485	Bacterial membrane protein, YfhO
C3496_02825	COG2246	polysaccharide biosynthetic process
C3496_02830	COG0463	Glycosyl transferase, family 2
C3496_02835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3496_02840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3496_02860	COG3584	3D domain protein
C3496_02875	COG1252	NADH dehydrogenase
C3496_02890	COG3708	Transcriptional regulator
C3496_02905	COG1683	Conserved Protein
C3496_02920	COG0316	Belongs to the HesB IscA family
C3496_02935	COG1252	NADH dehydrogenase
C3496_02950	COG0390	transport system, permease component
C3496_02955	COG2824	Alkylphosphonate utilization operon protein PhnA
C3496_02975	COG4837	Protein of unknown function (DUF1462)
C3496_02980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C3496_02990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_02995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3496_03010	COG1136	(ABC) transporter
C3496_03010	COG0577	efflux transmembrane transporter activity
C3496_03015	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_03025	COG0647	UMP catabolic process
C3496_03035	COG2445	Protein of unknown function DUF86
C3496_03040	COG1494	fructose-1,6-bisphosphatase
C3496_03060	COG4470	Protein conserved in bacteria
C3496_03070	COG0789	Transcriptional regulator
C3496_03075	COG4377	Putative membrane peptidase family (DUF2324)
C3496_03100	COG0739	heme binding
C3496_03110	COG3377	Domain of unknown function (DUF1805)
C3496_03115	COG0737	Belongs to the 5'-nucleotidase family
C3496_03125	COG0719	Fe-S assembly protein
C3496_03130	COG0822	iron-sulfur transferase activity
C3496_03135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C3496_03140	COG0719	Fe-S assembly protein
C3496_03145	COG0396	ATPase activity
C3496_03150	COG1464	Belongs to the NlpA lipoprotein family
C3496_03155	COG1464	Belongs to the NlpA lipoprotein family
C3496_03160	COG2011	ABC-type metal ion transport system permease component
C3496_03175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_03180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3496_03200	COG1393	Belongs to the ArsC family
C3496_03260	COG1309	transcriptional regulator
C3496_03265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_03270	COG1960	acyl-CoA dehydrogenase activity
C3496_03280	COG0183	Belongs to the thiolase family
C3496_03285	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_03285	COG1024	Enoyl-CoA hydratase
C3496_03300	COG1686	Belongs to the peptidase S11 family
C3496_03315	COG0011	TIGRFAM Protein of
C3496_03320	COG0840	transmembrane signaling receptor activity
C3496_03335	COG2814	Major facilitator Superfamily
C3496_03340	COG0531	amino acid
C3496_03355	COG0706	membrane insertase activity
C3496_03365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_03410	COG0586	Pfam SNARE associated Golgi protein
C3496_03420	COG1376	ErfK ybiS ycfS ynhG family protein
C3496_03425	COG0745	RESPONSE REGULATOR receiver
C3496_03430	COG5002	protein histidine kinase activity
C3496_03460	COG0840	transmembrane signaling receptor activity
C3496_03465	COG2151	metal-sulfur cluster biosynthetic enzyme
C3496_03470	COG3227	Zinc metalloprotease (Elastase)
C3496_03475	COG1741	Belongs to the pirin family
C3496_03490	COG0586	Pfam SNARE associated Golgi protein
C3496_03495	COG0475	glutathione-regulated potassium exporter activity
C3496_03500	COG0490	domain, Protein
C3496_03510	COG1115	amino acid carrier protein
C3496_03515	COG0783	Belongs to the Dps family
C3496_03530	COG1611	Belongs to the LOG family
C3496_03550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_03555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_03560	COG1115	amino acid carrier protein
C3496_03565	COG1115	amino acid carrier protein
C3496_03570	COG2910	NAD(P)H-binding
C3496_03590	COG0656	L-ascorbic acid biosynthetic process
C3496_03595	COG2814	Major facilitator Superfamily
C3496_03600	COG1733	regulation of RNA biosynthetic process
C3496_03610	COG1252	NADH dehydrogenase
C3496_03615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3496_03630	COG0840	transmembrane signaling receptor activity
C3496_03630	COG3290	protein histidine kinase activity
C3496_03640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3496_03660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_03720	COG0557	exoribonuclease II activity
C3496_03725	COG1647	Serine aminopeptidase, S33
C3496_03730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3496_03735	COG1346	cytolysis
C3496_03770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3496_03785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C3496_03810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_03825	COG2323	membrane
C3496_03835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_03845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C3496_03855	COG1051	belongs to the nudix hydrolase family
C3496_03865	COG0492	ferredoxin-NADP+ reductase activity
C3496_03870	COG0457	Tetratricopeptide repeat
C3496_03875	COG0110	maltose O-acetyltransferase activity
C3496_03895	COG1950	PFAM Membrane protein of
C3496_03905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C3496_03925	COG0789	Transcriptional regulator
C3496_03955	COG0583	DNA-binding transcription factor activity
C3496_03965	COG0655	NAD(P)H dehydrogenase (quinone) activity
C3496_03980	COG1132	(ABC) transporter
C3496_03985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_03990	COG0793	Belongs to the peptidase S41A family
C3496_03990	COG3409	Peptidoglycan-binding domain 1 protein
C3496_03995	COG2177	Part of the ABC transporter FtsEX involved in
C3496_04000	COG2884	Cell division ATP-binding protein ftsE
C3496_04020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C3496_04025	COG1278	Cold shock
C3496_04030	COG1040	competence protein
C3496_04035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C3496_04040	COG0791	NLP P60 protein
C3496_04040	COG1388	LysM domain
C3496_04045	COG1733	regulation of RNA biosynthetic process
C3496_04055	COG1307	EDD domain protein, DegV family
C3496_04060	COG1739	Uncharacterized protein family UPF0029
C3496_04065	COG1316	TRANSCRIPTIONal
C3496_04070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3496_04075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C3496_04080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3496_04090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C3496_04090	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C3496_04110	COG1486	melibiose metabolic process
C3496_04115	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_04120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_04130	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C3496_04140	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_04150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_04155	COG1301	dicarboxylic acid transport
C3496_04165	COG0346	lactoylglutathione lyase activity
C3496_04170	COG1511	domain protein
C3496_04175	COG0583	DNA-binding transcription factor activity
C3496_04180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C3496_04190	COG1271	oxidase subunit
C3496_04195	COG1294	oxidase, subunit
C3496_04200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_04210	COG1620	l-lactate permease
C3496_04220	COG2389	metal-binding protein
C3496_04235	COG1368	sulfuric ester hydrolase activity
C3496_04250	COG0791	NLP P60 protein
C3496_04250	COG1388	LysM domain
C3496_04255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_04265	COG1215	transferase activity, transferring glycosyl groups
C3496_04275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_04285	COG3584	3D domain protein
C3496_04285	COG1388	LysM domain
C3496_04295	COG4715	Zinc finger, swim domain protein
C3496_04300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_04340	COG0577	efflux transmembrane transporter activity
C3496_04345	COG1136	(ABC) transporter
C3496_04380	COG5002	protein histidine kinase activity
C3496_04385	COG0745	RESPONSE REGULATOR receiver
C3496_04390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3496_04410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3496_04425	COG1134	teichoic acid transport
C3496_04430	COG1682	transport, permease protein
C3496_04435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3496_04480	COG1609	Transcriptional regulator
C3496_04495	COG0739	heme binding
C3496_04510	COG3279	Response regulator of the LytR AlgR family
C3496_04515	COG2385	sporulation resulting in formation of a cellular spore
C3496_04530	COG4836	Membrane
C3496_04535	COG1007	ATP synthesis coupled electron transport
C3496_04540	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3496_04545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3496_04555	COG0839	Belongs to the complex I subunit 6 family
C3496_04575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3496_04590	COG5001	Diguanylate cyclase
C3496_04590	COG3300	MHYT domain
C3496_04640	COG0356	it plays a direct role in the translocation of protons across the membrane
C3496_04675	COG0698	ribose 5-phosphate isomerase
C3496_04690	COG2190	(PTS) system
C3496_04695	COG2259	Doxx family
C3496_04700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3496_04720	COG0009	L-threonylcarbamoyladenylate synthase
C3496_04735	COG2890	protein-(glutamine-N5) methyltransferase activity
C3496_04760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C3496_04765	COG1494	fructose-1,6-bisphosphatase
C3496_04790	COG4821	SIS domain
C3496_04810	COG1960	acyl-CoA dehydrogenase activity
C3496_04815	COG1960	acyl-CoA dehydrogenase activity
C3496_04820	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_04825	COG0183	Belongs to the thiolase family
C3496_04830	COG0247	lactate metabolic process
C3496_04830	COG2181	nitrate reductase activity
C3496_04835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_04845	COG3300	MHYT domain
C3496_04845	COG5001	Diguanylate cyclase
C3496_04865	COG2197	response regulator
C3496_04870	COG4585	Histidine kinase
C3496_04875	COG0842	Transport permease protein
C3496_04880	COG1131	(ABC) transporter
C3496_04885	COG0024	Methionine aminopeptidase
C3496_04895	COG2234	aminopeptidase activity
C3496_04915	COG1595	DNA-templated transcription, initiation
C3496_04925	COG4506	Protein conserved in bacteria
C3496_04930	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_04950	COG0010	Belongs to the arginase family
C3496_04960	COG2814	Major facilitator Superfamily
C3496_04965	COG0789	Transcriptional regulator
C3496_04970	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_04975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_04985	COG1994	Peptidase M50
C3496_04995	COG1078	dGTPase activity
C3496_05000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_05005	COG1120	ATPase activity
C3496_05010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_05015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_05035	COG0095	Lipoate-protein ligase
C3496_05040	COG0280	phosphate acetyltransferase
C3496_05055	COG3773	Cell wall hydrolase
C3496_05065	COG2363	Small membrane protein
C3496_05075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3496_05080	COG2233	PERMEase
C3496_05085	COG0561	phosphatase activity
C3496_05090	COG2814	Major facilitator Superfamily
C3496_05100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3496_05105	COG1131	(ABC) transporter
C3496_05110	COG2755	lipolytic protein G-D-S-L family
C3496_05115	COG1609	Transcriptional regulator
C3496_05125	COG0460	homoserine dehydrogenase
C3496_05135	COG2873	o-acetylhomoserine
C3496_05145	COG1011	Hydrolase
C3496_05150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3496_05160	COG2197	response regulator
C3496_05165	COG4585	Histidine kinase
C3496_05165	COG2203	Gaf domain
C3496_05170	COG0351	phosphomethylpyrimidine kinase
C3496_05175	COG3706	GGDEF domain
C3496_05180	COG2879	small protein
C3496_05185	COG1966	Carbon starvation protein
C3496_05190	COG3279	Response regulator of the LytR AlgR family
C3496_05195	COG0477	Major facilitator Superfamily
C3496_05220	COG0840	transmembrane signaling receptor activity
C3496_05230	COG1607	acyl-coa hydrolase
C3496_05245	COG0488	(ABC) transporter
C3496_05255	COG1309	transcriptional regulator
C3496_05260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3496_05265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_05265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_05270	COG0628	permease
C3496_05285	COG3279	Response regulator of the LytR AlgR family
C3496_05290	COG3275	phosphorelay sensor kinase activity
C3496_05295	COG2814	Major facilitator Superfamily
C3496_05300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_05305	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C3496_05315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_05335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3496_05340	COG1272	protein, Hemolysin III
C3496_05360	COG1164	Oligoendopeptidase f
C3496_05380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_05385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C3496_05390	COG4853	Protein conserved in bacteria
C3496_05395	COG4863	YycH protein
C3496_05400	COG5002	protein histidine kinase activity
C3496_05405	COG0745	RESPONSE REGULATOR receiver
C3496_05435	COG0305	Participates in initiation and elongation during chromosome replication
C3496_05445	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C3496_05450	COG4241	membrane
C3496_05460	COG0629	single-stranded DNA binding
C3496_05470	COG0012	GTP binding
C3496_05475	COG4481	Protein conserved in bacteria
C3496_05480	COG0668	transmembrane transport
C3496_05490	COG1475	DNA binding
C3496_05495	COG1192	Involved in chromosome partitioning
C3496_05520	COG1847	R3H domain protein
C3496_05525	COG0706	membrane insertase activity
C3496_05535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C3496_05545	COG0592	DNA-directed DNA polymerase activity
C3496_05550	COG2501	S4 domain
C3496_05560	COG0187	DNA topoisomerase II activity
C3496_05565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3496_05600	COG0517	IMP dehydrogenase activity
C3496_05600	COG0516	GMP reductase activity
C3496_05605	COG1686	Belongs to the peptidase S11 family
C3496_05635	COG1428	Deoxynucleoside kinase
C3496_05640	COG1428	Deoxynucleoside kinase
C3496_05645	COG1335	isochorismatase
C3496_05655	COG0590	tRNA wobble adenosine to inosine editing
C3496_05665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3496_05720	COG1982	Orn Lys Arg decarboxylase major
C3496_05730	COG0470	DNA polymerase III
C3496_05735	COG1774	PSP1 C-terminal conserved region
C3496_05745	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C3496_05760	COG2002	toxin-antitoxin pair type II binding
C3496_05765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_05765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_05770	COG0084	hydrolase, TatD family'
C3496_05775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3496_05790	COG4466	Protein conserved in bacteria
C3496_05805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3496_05815	COG0251	oxidation-reduction process
C3496_05845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3496_05850	COG2002	toxin-antitoxin pair type II binding
C3496_05855	COG2244	polysaccharide biosynthetic process
C3496_05860	COG3956	TIGRFAM MazG family protein
C3496_05865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3496_05885	COG1098	S1 RNA binding domain
C3496_05900	COG2208	phosphoserine phosphatase activity
C3496_05910	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3496_05915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3496_05930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_05935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3496_05940	COG0512	Glutamine amidotransferase of anthranilate synthase
C3496_05945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_05950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3496_05955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3496_05960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3496_05965	COG1396	sequence-specific DNA binding
C3496_05970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3496_06060	COG3880	PFAM UvrB UvrC protein
C3496_06070	COG0542	response to heat
C3496_06075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C3496_06085	COG4956	integral membrane protein (PIN domain superfamily)
C3496_06105	COG1045	serine acetyltransferase
C3496_06120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3496_06125	COG3688	RNA-binding protein containing a PIN domain
C3496_06140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3496_06145	COG0250	Participates in transcription elongation, termination and antitermination
C3496_06150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C3496_06170	COG2813	Specifically methylates the guanine in position
C3496_06185	COG1358	cellular component organization or biogenesis
C3496_06255	COG0255	Belongs to the universal ribosomal protein uL29 family
C3496_06315	COG0201	protein transport
C3496_06325	COG0024	Methionine aminopeptidase
C3496_06335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3496_06370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3496_06395	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_06400	COG0489	protein tyrosine kinase activity
C3496_06410	COG2194	sulfuric ester hydrolase activity
C3496_06415	COG0726	polysaccharide deacetylase
C3496_06495	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C3496_06500	COG4856	YbbR-like protein
C3496_06600	COG0596	Alpha beta hydrolase
C3496_06620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C3496_06625	COG0823	Involved in the tonB-independent uptake of proteins
C3496_06625	COG4946	Tricorn protease homolog
C3496_06625	COG1506	peptidase
C3496_06655	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_06660	COG2011	ABC-type metal ion transport system permease component
C3496_06670	COG1464	Belongs to the NlpA lipoprotein family
C3496_06675	COG0604	alcohol dehydrogenase
C3496_06685	COG0277	FAD linked oxidase domain protein
C3496_06690	COG2271	Major facilitator Superfamily
C3496_06700	COG2814	Major facilitator Superfamily
C3496_06715	COG0601	transmembrane transport
C3496_06720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_06725	COG0444	Belongs to the ABC transporter superfamily
C3496_06730	COG4608	Belongs to the ABC transporter superfamily
C3496_06735	COG4166	transmembrane transport
C3496_06745	COG2207	Transcriptional regulator
C3496_06755	COG1309	transcriptional regulator
C3496_06765	COG4166	transmembrane transport
C3496_06770	COG4166	transmembrane transport
C3496_06775	COG0656	L-ascorbic acid biosynthetic process
C3496_06780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_06795	COG4149	molybdate abc transporter
C3496_06800	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3496_06805	COG1910	domain protein
C3496_06825	COG0697	spore germination
C3496_06840	COG0204	Acyl-transferase
C3496_06855	COG1609	Transcriptional regulator
C3496_06865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_06890	COG5298	Protein conserved in bacteria
C3496_06915	COG0488	(ABC) transporter
C3496_06920	COG4585	Histidine kinase
C3496_06925	COG2197	response regulator
C3496_06930	COG1131	(ABC) transporter
C3496_06935	COG1511	domain protein
C3496_06935	COG0842	Transport permease protein
C3496_06940	COG0842	Transport permease protein
C3496_06955	COG0747	negative chemotaxis
C3496_06960	COG0601	transmembrane transport
C3496_06965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_06970	COG0444	Belongs to the ABC transporter superfamily
C3496_06975	COG4608	Belongs to the ABC transporter superfamily
C3496_06980	COG0561	phosphatase activity
C3496_07015	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C3496_07020	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3496_07035	COG0531	amino acid
C3496_07050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3496_07060	COG4294	response to UV
C3496_07065	COG0705	Rhomboid family
C3496_07075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C3496_07080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3496_07085	COG0864	Transcriptional regulator
C3496_07090	COG2337	Toxic component of a toxin-antitoxin (TA) module
C3496_07095	COG2183	response to ionizing radiation
C3496_07190	COG0802	atpase or kinase
C3496_07195	COG1214	PFAM Peptidase M22, glycoprotease
C3496_07200	COG0456	acetyltransferase
C3496_07210	COG0488	(ABC) transporter
C3496_07225	COG1266	CAAX protease self-immunity
C3496_07245	COG2252	PERMEase
C3496_07255	COG5002	protein histidine kinase activity
C3496_07280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3496_07355	COG2205	protein histidine kinase activity
C3496_07360	COG0745	RESPONSE REGULATOR receiver
C3496_07380	COG0697	spore germination
C3496_07410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C3496_07415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3496_07420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C3496_07430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3496_07445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C3496_07455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3496_07465	COG0151	Belongs to the GarS family
C3496_07495	COG0210	DNA helicase
C3496_07505	COG4851	CamS sex pheromone cAM373 precursor
C3496_07525	COG1335	isochorismatase
C3496_07540	COG2011	ABC-type metal ion transport system permease component
C3496_07545	COG1464	Belongs to the NlpA lipoprotein family
C3496_07560	COG0003	Pfam Anion-transporting ATPase
C3496_07565	COG1846	Transcriptional regulator
C3496_07570	COG4682	membrane
C3496_07590	COG1597	lipid kinase activity
C3496_07595	COG0546	phosphoglycolate phosphatase activity
C3496_07600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3496_07610	COG1012	belongs to the aldehyde dehydrogenase family
C3496_07615	COG2076	Multidrug Resistance protein
C3496_07620	COG2309	aminopeptidase activity
C3496_07635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_07640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3496_07645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3496_07655	COG5002	protein histidine kinase activity
C3496_07660	COG4807	Protein conserved in bacteria
C3496_07685	COG1757	Na H antiporter
C3496_07690	COG1473	amidohydrolase
C3496_07705	COG0450	alkyl hydroperoxide reductase
C3496_07725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_07730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_07735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_07760	COG0166	Belongs to the GPI family
C3496_07795	COG5002	protein histidine kinase activity
C3496_07815	COG3541	Predicted nucleotidyltransferase
C3496_07820	COG2814	Major facilitator Superfamily
C3496_07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_07825	COG0723	plastoquinol--plastocyanin reductase activity
C3496_07835	COG0765	amino acid transport
C3496_07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_07850	COG0840	transmembrane signaling receptor activity
C3496_07855	COG0366	Alpha amylase catalytic
C3496_07860	COG2190	(PTS) system
C3496_07860	COG1263	PTS System
C3496_07860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_07895	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C3496_07910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_07920	COG1116	anion transmembrane transporter activity
C3496_07925	COG0488	(ABC) transporter
C3496_07970	COG2270	Major facilitator Superfamily
C3496_07995	COG4193	domain, Protein
C3496_08005	COG2310	stress, protein
C3496_08010	COG2310	stress, protein
C3496_08015	COG2310	stress, protein
C3496_08020	COG0861	Integral membrane protein TerC family
C3496_08030	COG3853	Toxic anion resistance protein (TelA)
C3496_08045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3496_08055	COG1295	ribonuclease BN
C3496_08065	COG2217	Heavy metal translocating P-type atpase
C3496_08070	COG0697	spore germination
C3496_08080	COG0681	Belongs to the peptidase S26 family
C3496_08090	COG0586	Pfam SNARE associated Golgi protein
C3496_08105	COG3871	stress protein (general stress protein 26)
C3496_08110	COG0387	Pfam Sodium calcium exchanger
C3496_08120	COG0535	radical SAM domain protein
C3496_08140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C3496_08160	COG3829	transcription factor binding
C3496_08170	COG0833	amino acid
C3496_08175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_08215	COG1263	PTS System
C3496_08215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_08220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_08240	COG0463	Glycosyl transferase, family 2
C3496_08265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C3496_08285	COG1228	amidohydrolase
C3496_08290	COG1090	epimerase
C3496_08320	COG1988	membrane-bound metal-dependent
C3496_08325	COG1194	a g-specific adenine glycosylase
C3496_08350	COG1132	(ABC) transporter
C3496_08355	COG4129	membrane
C3496_08360	COG0070	glutamate synthase
C3496_08360	COG0069	glutamate synthase activity
C3496_08360	COG0067	glutamate synthase
C3496_08370	COG4555	ABC transporter
C3496_08390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3496_08395	COG0735	belongs to the Fur family
C3496_08515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C3496_08520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3496_08530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3496_08540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3496_08555	COG2766	serine protein kinase
C3496_08585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_08595	COG1585	Membrane protein implicated in regulation of membrane protease activity
C3496_08600	COG2268	Band 7 protein
C3496_08610	COG3290	protein histidine kinase activity
C3496_08615	COG4565	transcriptional regulatory protein
C3496_08620	COG2851	Citrate transporter
C3496_08650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C3496_08655	COG3842	ATPase activity
C3496_08660	COG1175	transmembrane transport
C3496_08665	COG0395	ABC-type sugar transport system, permease component
C3496_08675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3496_08680	COG0745	RESPONSE REGULATOR receiver
C3496_08685	COG5002	protein histidine kinase activity
C3496_08695	COG4990	cell redox homeostasis
C3496_08705	COG3290	protein histidine kinase activity
C3496_08710	COG4565	transcriptional regulatory protein
C3496_08715	COG3493	citrate carrier protein
C3496_08720	COG0281	malic enzyme
C3496_08730	COG0697	spore germination
C3496_08735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_08745	COG5002	protein histidine kinase activity
C3496_08750	COG0745	RESPONSE REGULATOR receiver
C3496_08760	COG0456	acetyltransferase
C3496_08760	COG0454	-acetyltransferase
C3496_08765	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3496_08770	COG3383	formate dehydrogenase (NAD+) activity
C3496_08775	COG2427	Protein of unknown function (DUF1641)
C3496_08790	COG0531	amino acid
C3496_08800	COG0640	Transcriptional regulator
C3496_08805	COG2217	Heavy metal translocating P-type atpase
C3496_08810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C3496_08820	COG3227	Zinc metalloprotease (Elastase)
C3496_08840	COG2720	vancomycin resistance protein
C3496_08845	COG1316	TRANSCRIPTIONal
C3496_08850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_08855	COG0346	lactoylglutathione lyase activity
C3496_08860	COG1253	flavin adenine dinucleotide binding
C3496_08865	COG1027	Aspartate ammonia-lyase
C3496_08870	COG1620	l-lactate permease
C3496_08885	COG3104	oligopeptide transport
C3496_08890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_08895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_08900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_08910	COG2226	methyltransferase
C3496_08915	COG0156	8-amino-7-oxononanoate synthase activity
C3496_08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3496_08925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C3496_08935	COG4548	von Willebrand factor, type A
C3496_08940	COG0714	Associated with various cellular activities
C3496_08945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_08965	COG0531	amino acid
C3496_08970	COG2188	Transcriptional regulator
C3496_08975	COG1263	PTS System
C3496_08975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_08980	COG0366	Alpha amylase catalytic
C3496_08995	COG0697	spore germination
C3496_09005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_09010	COG1115	amino acid carrier protein
C3496_09020	COG1126	abc transporter atp-binding protein
C3496_09025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_09030	COG0765	amino acid transport
C3496_09035	COG0765	amino acid transport
C3496_09040	COG0833	amino acid
C3496_09065	COG2378	regulation of single-species biofilm formation
C3496_09070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3496_09075	COG5002	protein histidine kinase activity
C3496_09090	COG0659	secondary active sulfate transmembrane transporter activity
C3496_09105	COG0747	negative chemotaxis
C3496_09115	COG0601	transmembrane transport
C3496_09120	COG4608	Belongs to the ABC transporter superfamily
C3496_09130	COG2271	Major facilitator Superfamily
C3496_09135	COG1846	Transcriptional regulator
C3496_09140	COG0477	Major facilitator Superfamily
C3496_09145	COG1609	Transcriptional regulator
C3496_09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3496_09165	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3496_09170	COG1879	ABC-type sugar transport system periplasmic component
C3496_09185	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_09195	COG1063	alcohol dehydrogenase
C3496_09210	COG3568	Endonuclease Exonuclease Phosphatase
C3496_09240	COG0840	transmembrane signaling receptor activity
C3496_09245	COG1388	LysM domain
C3496_09245	COG3584	3D domain protein
C3496_09250	COG1476	TRANSCRIPTIONal
C3496_09265	COG3104	oligopeptide transport
C3496_09270	COG1114	Component of the transport system for branched-chain amino acids
C3496_09285	COG1113	amino acid transport
C3496_09290	COG2252	PERMEase
C3496_09305	COG2153	protein acetylation
C3496_09315	COG0569	domain protein
C3496_09315	COG0475	glutathione-regulated potassium exporter activity
C3496_09330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3496_09335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3496_09340	COG0833	amino acid
C3496_09345	COG4990	cell redox homeostasis
C3496_09360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_09365	COG0697	spore germination
C3496_09370	COG0531	amino acid
C3496_09385	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_09390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_09395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_09395	COG1918	ferrous iron import across plasma membrane
C3496_09400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3496_09405	COG0573	inorganic phosphate transmembrane transporter activity
C3496_09410	COG0581	inorganic phosphate transmembrane transporter activity
C3496_09420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3496_09540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C3496_09565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3496_09570	COG1116	anion transmembrane transporter activity
C3496_09575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_09580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_09585	COG0352	thiamine-phosphate diphosphorylase activity
C3496_09590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_09595	COG2104	thiamine diphosphate biosynthetic process
C3496_09605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_09610	COG0351	phosphomethylpyrimidine kinase
C3496_09655	COG2205	protein histidine kinase activity
C3496_09660	COG2814	Major facilitator Superfamily
C3496_09665	COG1846	Transcriptional regulator
C3496_09680	COG2252	PERMEase
C3496_09685	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_09705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_09745	COG0778	Nitroreductase
C3496_09750	COG2719	SpoVR family
C3496_09760	COG1414	Transcriptional regulator
C3496_09780	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3496_09785	COG1937	Protein conserved in bacteria
C3496_09790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_09790	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_09795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_09795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_09800	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_09805	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_09815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_09815	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_09825	COG2210	Belongs to the sulfur carrier protein TusA family
C3496_09830	COG0730	response to heat
C3496_09840	COG1316	TRANSCRIPTIONal
C3496_09845	COG0604	alcohol dehydrogenase
C3496_09865	COG3711	transcriptional antiterminator
C3496_09865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_09870	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_09875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_09895	COG3584	3D domain protein
C3496_09895	COG1388	LysM domain
C3496_09900	COG0577	efflux transmembrane transporter activity
C3496_09905	COG1136	(ABC) transporter
C3496_09915	COG5522	Integral membrane protein (intg_mem_TP0381)
C3496_09930	COG0577	efflux transmembrane transporter activity
C3496_09935	COG1114	Component of the transport system for branched-chain amino acids
C3496_09940	COG3546	catalase activity
C3496_09975	COG0586	Pfam SNARE associated Golgi protein
C3496_10010	COG0531	amino acid
C3496_10015	COG0475	glutathione-regulated potassium exporter activity
C3496_10025	COG1737	Transcriptional regulator
C3496_10035	COG1263	PTS System
C3496_10035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_10045	COG2259	Doxx family
C3496_10065	COG1522	sequence-specific DNA binding
C3496_10080	COG2076	Multidrug Resistance protein
C3496_10085	COG1309	transcriptional regulator
C3496_10090	COG2814	Major facilitator Superfamily
C3496_10095	COG1733	regulation of RNA biosynthetic process
C3496_10105	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_10110	COG4533	DNA binding
C3496_10115	COG2211	Major facilitator Superfamily
C3496_10125	COG0693	protein deglycase activity
C3496_10130	COG0753	catalase activity
C3496_10130	COG0693	protein deglycase activity
C3496_10140	COG0531	amino acid
C3496_10145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C3496_10155	COG1012	belongs to the aldehyde dehydrogenase family
C3496_10175	COG1132	(ABC) transporter
C3496_10180	COG1132	(ABC) transporter
C3496_10190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_10195	COG0765	amino acid transport
C3496_10200	COG1126	abc transporter atp-binding protein
C3496_10215	COG0189	ligase activity
C3496_10245	COG0028	Belongs to the TPP enzyme family
C3496_10250	COG3527	Alpha-acetolactate decarboxylase
C3496_10265	COG0561	phosphatase activity
C3496_10285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3496_10305	COG0659	secondary active sulfate transmembrane transporter activity
C3496_10315	COG1024	Enoyl-CoA hydratase
C3496_10330	COG1363	Peptidase, m42
C3496_10350	COG3938	Belongs to the proline racemase family
C3496_10375	COG0601	transmembrane transport
C3496_10380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_10385	COG0444	Belongs to the ABC transporter superfamily
C3496_10390	COG4608	Belongs to the ABC transporter superfamily
C3496_10400	COG0477	Major facilitator Superfamily
C3496_10405	COG3290	protein histidine kinase activity
C3496_10410	COG4565	transcriptional regulatory protein
C3496_10415	COG3181	Tripartite tricarboxylate transporter family receptor
C3496_10500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C3496_10510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C3496_10525	COG0789	Transcriptional regulator
C3496_10525	COG4978	Transcriptional regulator
C3496_10540	COG0305	Participates in initiation and elongation during chromosome replication
C3496_10565	COG0477	Major facilitator Superfamily
C3496_10620	COG3320	Male sterility
C3496_10620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_10625	COG1309	transcriptional regulator
C3496_10635	COG3711	transcriptional antiterminator
C3496_10640	COG1263	PTS System
C3496_10640	COG2190	(PTS) system
C3496_10640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_10645	COG2723	6-phospho-beta-galactosidase activity
C3496_10655	COG1183	phosphatidylcholine synthase activity
C3496_10700	COG2376	Dihydroxyacetone kinase
C3496_10715	COG2376	Dihydroxyacetone kinase
C3496_10830	COG3237	CsbD-like
C3496_10855	COG1191	sigma factor activity
C3496_10865	COG2208	phosphoserine phosphatase activity
C3496_10870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3496_10875	COG0784	Response regulator, receiver
C3496_10875	COG2205	protein histidine kinase activity
C3496_10875	COG2198	Histidine kinase
C3496_10925	COG4585	Histidine kinase
C3496_10930	COG2197	response regulator
C3496_10960	COG0420	3'-5' exonuclease activity
C3496_10965	COG4717	serine-type aminopeptidase activity
C3496_11000	COG0346	lactoylglutathione lyase activity
C3496_11005	COG0346	lactoylglutathione lyase activity
C3496_11010	COG0457	Tetratricopeptide repeat
C3496_11020	COG2267	carboxylic ester hydrolase activity
C3496_11050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C3496_11055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C3496_11065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C3496_11085	COG0772	Belongs to the SEDS family
C3496_11100	COG0477	Major facilitator Superfamily
C3496_11105	COG0477	Major facilitator Superfamily
C3496_11115	COG3973	AAA domain
C3496_11120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_11145	COG4980	gas vesicle protein
C3496_11150	COG0537	adenosine 5'-monophosphoramidase activity
C3496_11160	COG1131	(ABC) transporter
C3496_11165	COG4473	ABC transporter
C3496_11245	COG1309	transcriptional regulator
C3496_11255	COG3402	PFAM membrane-flanked domain
C3496_11260	COG3428	Bacterial PH domain
C3496_11280	COG3402	PFAM membrane-flanked domain
C3496_11285	COG3428	Bacterial PH domain
C3496_11290	COG2329	Antibiotic biosynthesis monooxygenase
C3496_11295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_11310	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3496_11345	COG1309	transcriptional regulator
C3496_11350	COG1511	domain protein
C3496_11365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_11375	COG2378	regulation of single-species biofilm formation
C3496_11385	COG1609	Transcriptional regulator
C3496_11395	COG1234	tRNA 3'-trailer cleavage
C3496_11400	COG0095	Lipoate-protein ligase
C3496_11410	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_11430	COG1408	metallophosphoesterase
C3496_11440	COG1078	dGTPase activity
C3496_11450	COG0477	Major facilitator Superfamily
C3496_11460	COG1595	DNA-templated transcription, initiation
C3496_11470	COG3708	Transcriptional regulator
C3496_11470	COG2207	Transcriptional regulator
C3496_11485	COG2205	protein histidine kinase activity
C3496_11490	COG0745	RESPONSE REGULATOR receiver
C3496_11515	COG0501	Belongs to the peptidase M48B family
C3496_11520	COG0840	transmembrane signaling receptor activity
C3496_11525	COG0697	spore germination
C3496_11535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C3496_11540	COG2224	Isocitrate lyase
C3496_11570	COG4903	ComK protein
C3496_11575	COG0398	Pfam SNARE associated Golgi protein
C3496_11590	COG1074	ATP-dependent DNA helicase activity
C3496_11635	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3496_11660	COG0367	asparagine synthase
C3496_11670	COG0753	catalase activity
C3496_11675	COG0004	ammonium transporteR
C3496_11700	COG2996	Protein conserved in bacteria
C3496_11705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_11715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_11730	COG0561	phosphatase activity
C3496_11745	COG0542	response to heat
C3496_11755	COG2267	carboxylic ester hydrolase activity
C3496_11775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_11780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3496_11785	COG5504	Zn-dependent protease
C3496_11800	COG0180	Tryptophanyl-tRNA synthetase
C3496_11815	COG4166	transmembrane transport
C3496_11820	COG0601	transmembrane transport
C3496_11825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_11830	COG0444	Belongs to the ABC transporter superfamily
C3496_11835	COG4608	Belongs to the ABC transporter superfamily
C3496_11840	COG0534	Mate efflux family protein
C3496_11845	COG4166	transmembrane transport
C3496_11865	COG0861	Integral membrane protein TerC family
C3496_11870	COG4862	establishment of competence for transformation
C3496_11875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_11885	COG1164	Oligoendopeptidase f
C3496_11900	COG2346	COG2346, Truncated hemoglobins
C3496_11905	COG4116	CYTH
C3496_11915	COG2357	RelA SpoT domain protein
C3496_11925	COG0564	pseudouridine synthase activity
C3496_11940	COG0772	Belongs to the SEDS family
C3496_11945	COG1216	Glycosyl transferase, family 2
C3496_11945	COG0463	Glycosyl transferase, family 2
C3496_11965	COG0463	Glycosyl transferase, family 2
C3496_11965	COG0457	Tetratricopeptide repeat
C3496_11985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3496_12000	COG1091	dTDP-4-dehydrorhamnose reductase activity
C3496_12045	COG2153	protein acetylation
C3496_12055	COG2382	esterase
C3496_12070	COG5492	domain, Protein
C3496_12075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_12090	COG0512	Glutamine amidotransferase of anthranilate synthase
C3496_12090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C3496_12125	COG1620	l-lactate permease
C3496_12130	COG5634	Uncharacterized conserved protein (DUF2278)
C3496_12195	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_12205	COG1476	TRANSCRIPTIONal
C3496_12335	COG4974	Belongs to the 'phage' integrase family
C3496_12345	COG2226	methyltransferase
C3496_12360	COG1686	Belongs to the peptidase S11 family
C3496_12365	COG0681	Belongs to the peptidase S26 family
C3496_12385	COG1396	sequence-specific DNA binding
C3496_12400	COG1012	belongs to the aldehyde dehydrogenase family
C3496_12410	COG1176	ABC-type spermidine putrescine transport system, permease component I
C3496_12415	COG1177	transmembrane transport
C3496_12420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C3496_12430	COG2409	Drug exporters of the RND superfamily
C3496_12440	COG0564	pseudouridine synthase activity
C3496_12450	COG2340	Cysteine-rich secretory protein family
C3496_12455	COG0247	lactate metabolic process
C3496_12460	COG0277	FAD linked oxidase domain protein
C3496_12465	COG3835	regulator
C3496_12475	COG0745	RESPONSE REGULATOR receiver
C3496_12480	COG5002	protein histidine kinase activity
C3496_12485	COG2186	Transcriptional regulator
C3496_12505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C3496_12515	COG2116	formate transmembrane transporter activity
C3496_12520	COG0861	Integral membrane protein TerC family
C3496_12525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_12535	COG2030	dehydratase
C3496_12555	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_12560	COG3243	poly(R)-hydroxyalkanoic acid synthase
C3496_12570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_12590	COG1840	ABC-type Fe3 transport system, periplasmic component
C3496_12595	COG3842	ATPase activity
C3496_12620	COG1349	DNA-binding transcription factor activity
C3496_12635	COG0235	Class ii aldolase
C3496_12645	COG2861	carbohydrate metabolic process
C3496_12655	COG3852	Histidine kinase
C3496_12660	COG1846	Transcriptional regulator
C3496_12670	COG2318	DinB family
C3496_12680	COG5002	protein histidine kinase activity
C3496_12690	COG0720	synthase
C3496_12705	COG4873	Protein conserved in bacteria
C3496_12740	COG1780	Probably involved in ribonucleotide reductase function
C3496_12755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3496_12760	COG1725	Transcriptional regulator
C3496_12765	COG1131	(ABC) transporter
C3496_12775	COG1131	(ABC) transporter
C3496_12780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3496_12785	COG1266	CAAX protease self-immunity
C3496_12795	COG1522	sequence-specific DNA binding
C3496_12805	COG1335	isochorismatase
C3496_12815	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_12820	COG2070	2-Nitropropane dioxygenase
C3496_12825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C3496_12835	COG1696	Membrane protein involved in D-alanine export
C3496_12860	COG0716	FMN binding
C3496_12875	COG3173	Aminoglycoside phosphotransferase
C3496_12905	COG1968	undecaprenyl-diphosphatase activity
C3496_12920	COG1846	Transcriptional regulator
C3496_12930	COG1301	dicarboxylic acid transport
C3496_12935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_12940	COG4709	membrane
C3496_12945	COG3874	Sporulation protein YtfJ
C3496_12975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_12980	COG0028	Belongs to the TPP enzyme family
C3496_12985	COG0440	acetolactate synthase activity
C3496_13060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3496_13075	COG1183	phosphatidylcholine synthase activity
C3496_13080	COG1368	sulfuric ester hydrolase activity
C3496_13090	COG0019	diaminopimelate decarboxylase activity
C3496_13110	COG0529	Catalyzes the synthesis of activated sulfate
C3496_13115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3496_13135	COG1648	precorrin-2 dehydrogenase activity
C3496_13145	COG0733	neurotransmitter:sodium symporter activity
C3496_13165	COG1757	Na H antiporter
C3496_13180	COG4758	membrane
C3496_13185	COG4585	Histidine kinase
C3496_13190	COG2197	response regulator
C3496_13200	COG1114	Component of the transport system for branched-chain amino acids
C3496_13210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3496_13225	COG1994	Peptidase M50
C3496_13255	COG0730	response to heat
C3496_13260	COG0306	phosphate transporter
C3496_13265	COG1392	Phosphate transport regulator
C3496_13270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_13285	COG3852	Histidine kinase
C3496_13290	COG1801	Protein of unknown function DUF72
C3496_13300	COG0582	viral genome integration into host DNA
C3496_13305	COG5002	protein histidine kinase activity
C3496_13320	COG0392	lysyltransferase activity
C3496_13320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C3496_13335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_13340	COG1686	Belongs to the peptidase S11 family
C3496_13345	COG2715	membrane protein required for spore maturation
C3496_13350	COG0700	Nucleoside recognition
C3496_13355	COG1187	pseudouridine synthase activity
C3496_13365	COG1333	cytochrome c biogenesis protein
C3496_13370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3496_13375	COG0745	RESPONSE REGULATOR receiver
C3496_13380	COG5002	protein histidine kinase activity
C3496_13385	COG2096	Adenosyltransferase
C3496_13390	COG4942	peptidase
C3496_13400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C3496_13405	COG1141	Ferredoxin
C3496_13415	COG0514	ATP-dependent DNA helicase (RecQ)
C3496_13420	COG1266	CAAX protease self-immunity
C3496_13430	COG1408	metallophosphoesterase
C3496_13440	COG4862	establishment of competence for transformation
C3496_13445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3496_13465	COG0492	ferredoxin-NADP+ reductase activity
C3496_13540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_13555	COG0142	geranyltranstransferase activity
C3496_13565	COG0142	geranyltranstransferase activity
C3496_13590	COG0457	Tetratricopeptide repeat
C3496_13610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C3496_13625	COG4347	Protein of unknown function (DUF1405)
C3496_13640	COG2738	Putative neutral zinc metallopeptidase
C3496_13650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_13660	COG1694	Mazg nucleotide pyrophosphohydrolase
C3496_13675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_13680	COG0438	transferase activity, transferring glycosyl groups
C3496_13720	COG1199	ATP-dependent helicase activity
C3496_13720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3496_13740	COG3935	DnaD domain protein
C3496_13745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3496_13755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_13755	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3496_13815	COG0116	Belongs to the methyltransferase superfamily
C3496_13825	COG1199	ATP-dependent helicase activity
C3496_13830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C3496_13840	COG3173	Aminoglycoside phosphotransferase
C3496_13845	COG0024	Methionine aminopeptidase
C3496_13855	COG2233	PERMEase
C3496_13860	COG2311	Membrane
C3496_13870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_13880	COG0456	acetyltransferase
C3496_13915	COG0754	glutathionylspermidine amidase activity
C3496_13930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_13955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3496_13970	COG1215	transferase activity, transferring glycosyl groups
C3496_13975	COG0438	transferase activity, transferring glycosyl groups
C3496_14010	COG0328	RNA-DNA hybrid ribonuclease activity
C3496_14045	COG3403	YqcI/YcgG family
C3496_14050	COG1280	lysine exporter protein (LysE YggA)
C3496_14065	COG3162	membrane
C3496_14070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_14075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_14085	COG0475	glutathione-regulated potassium exporter activity
C3496_14090	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_14095	COG0789	Transcriptional regulator
C3496_14095	COG4978	Transcriptional regulator
C3496_14105	COG2323	membrane
C3496_14110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C3496_14165	COG1923	regulation of RNA biosynthetic process
C3496_14175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3496_14180	COG1360	Flagellar Motor Protein
C3496_14185	COG2201	protein-glutamate methylesterase activity
C3496_14190	COG0643	Histidine kinase
C3496_14190	COG2198	Histidine kinase
C3496_14195	COG1776	CheC inhibitor of MCP methylation
C3496_14195	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_14210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3496_14230	COG1256	bacterial-type flagellum assembly
C3496_14235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_14255	COG1815	bacterial-type flagellum-dependent cell motility
C3496_14260	COG1558	bacterial-type flagellum-dependent cell motility
C3496_14270	COG1766	The M ring may be actively involved in energy transduction
C3496_14275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_14285	COG1157	protein secretion by the type III secretion system
C3496_14320	COG0835	chemotaxis
C3496_14320	COG0784	Response regulator, receiver
C3496_14330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_14335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_14340	COG0741	lytic transglycosylase activity
C3496_14350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_14355	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_14355	COG1776	CheC inhibitor of MCP methylation
C3496_14365	COG1338	Plays a role in the flagellum-specific transport system
C3496_14370	COG1987	bacterial-type flagellum assembly
C3496_14380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3496_14385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3496_14390	COG1419	protein localization to endoplasmic reticulum
C3496_14395	COG4786	Flagellar basal body rod
C3496_14400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3496_14425	COG1309	transcriptional regulator
C3496_14445	COG2329	Antibiotic biosynthesis monooxygenase
C3496_14470	COG0583	DNA-binding transcription factor activity
C3496_14475	COG3842	ATPase activity
C3496_14480	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3496_14490	COG1234	tRNA 3'-trailer cleavage
C3496_14520	COG1686	Belongs to the peptidase S11 family
C3496_14530	COG0406	alpha-ribazole phosphatase activity
C3496_14545	COG1846	Transcriptional regulator
C3496_14555	COG0367	asparagine synthase
C3496_14585	COG1802	Transcriptional regulator
C3496_14590	COG0697	spore germination
C3496_14595	COG0523	cobalamin synthesis protein
C3496_14610	COG0438	transferase activity, transferring glycosyl groups
C3496_14610	COG1216	Glycosyl transferase, family 2
C3496_14615	COG1757	Na H antiporter
C3496_14620	COG0789	Transcriptional regulator
C3496_14630	COG0114	fumarate hydratase activity
C3496_14650	COG0534	Mate efflux family protein
C3496_14660	COG3340	Belongs to the peptidase S51 family
C3496_14680	COG0785	Cytochrome C biogenesis protein
C3496_14705	COG2733	membrane
C3496_14745	COG1131	(ABC) transporter
C3496_14760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_14765	COG0528	UMP kinase activity
C3496_14775	COG1027	Aspartate ammonia-lyase
C3496_14780	COG0281	malic enzyme
C3496_14785	COG4191	Histidine kinase
C3496_14790	COG0784	Response regulator, receiver
C3496_14795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_14820	COG3620	sequence-specific DNA binding
C3496_14860	COG2814	Major facilitator Superfamily
C3496_14875	COG1966	Carbon starvation protein
C3496_14890	COG0477	Major facilitator Superfamily
C3496_14895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_14900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3496_14905	COG4166	transmembrane transport
C3496_14910	COG2223	nitrite transmembrane transporter activity
C3496_14915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_14930	COG2244	polysaccharide biosynthetic process
C3496_14935	COG0733	neurotransmitter:sodium symporter activity
C3496_14945	COG5566	PFAM Mor transcription activator
C3496_14950	COG2323	membrane
C3496_14975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_14985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_14990	COG0028	Belongs to the TPP enzyme family
C3496_15000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C3496_15010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3496_15035	COG2814	Major facilitator Superfamily
C3496_15040	COG3384	dioxygenase
C3496_15050	COG3279	Response regulator of the LytR AlgR family
C3496_15055	COG0427	acetyl-CoA hydrolase
C3496_15075	COG1073	alpha beta
C3496_15080	COG1131	(ABC) transporter
C3496_15085	COG4166	transmembrane transport
C3496_15110	COG0535	radical SAM domain protein
C3496_15115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_15140	COG1914	H( )-stimulated, divalent metal cation uptake system
C3496_15155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3496_15160	COG0531	amino acid
C3496_15195	COG0714	Associated with various cellular activities
C3496_15205	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C3496_15230	COG2390	Transcriptional regulator
C3496_15240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_15245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C3496_15255	COG4846	Membrane protein involved in cytochrome C biogenesis
C3496_15285	COG2132	Multicopper oxidase
C3496_15300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3496_15345	COG1114	Component of the transport system for branched-chain amino acids
C3496_15355	COG2372	response to copper ion
C3496_15355	COG1276	copper resistance
C3496_15360	COG4549	nuclear export factor GLE1
C3496_15370	COG0697	spore germination
C3496_15375	COG0583	DNA-binding transcription factor activity
C3496_15380	COG1959	2 iron, 2 sulfur cluster binding
C3496_15385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3496_15390	COG0778	Nitroreductase
C3496_15405	COG0628	permease
C3496_15420	COG1231	oxidoreductase activity
C3496_15430	COG0523	cobalamin synthesis protein
C3496_15440	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_15445	COG2030	dehydratase
C3496_15450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_15465	COG0411	ABC transporter
C3496_15485	COG0583	DNA-binding transcription factor activity
C3496_15495	COG1942	4-Oxalocrotonate Tautomerase
C3496_15515	COG1271	oxidase subunit
C3496_15520	COG1294	oxidase, subunit
C3496_15525	COG4988	ABC transporter
C3496_15530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C3496_15550	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_15555	COG1686	Belongs to the peptidase S11 family
C3496_15570	COG1388	LysM domain
C3496_15570	COG0791	NLP P60 protein
C3496_15580	COG1132	(ABC) transporter
C3496_15585	COG0745	RESPONSE REGULATOR receiver
C3496_15590	COG5002	protein histidine kinase activity
C3496_15600	COG0300	oxidoreductase activity
C3496_15605	COG4122	O-methyltransferase activity
C3496_15640	COG0460	homoserine dehydrogenase
C3496_15665	COG1316	TRANSCRIPTIONal
C3496_15675	COG0745	RESPONSE REGULATOR receiver
C3496_15680	COG5002	protein histidine kinase activity
C3496_15695	COG1285	pathogenesis
C3496_15700	COG1247	-acetyltransferase
C3496_15720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_15730	COG1082	Xylose isomerase domain protein TIM barrel
C3496_15740	COG2814	Major facilitator Superfamily
C3496_15745	COG1279	arginine transmembrane transporter activity
C3496_15750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_15760	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3496_15795	COG0577	efflux transmembrane transporter activity
C3496_15800	COG2002	toxin-antitoxin pair type II binding
C3496_15805	COG1404	Belongs to the peptidase S8 family
C3496_15810	COG0640	Transcriptional regulator
C3496_15815	COG0667	Aldo Keto reductase
C3496_15825	COG2814	Major facilitator Superfamily
C3496_15850	COG0840	transmembrane signaling receptor activity
C3496_15870	COG3949	Membrane
C3496_15875	COG0783	Belongs to the Dps family
C3496_15890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_15900	COG1231	oxidoreductase activity
C3496_15910	COG4989	oxidoreductase activity
C3496_15920	COG0523	cobalamin synthesis protein
C3496_15925	COG0456	acetyltransferase
C3496_15930	COG3443	Belongs to the bacterial solute-binding protein 9 family
C3496_15930	COG0803	Belongs to the bacterial solute-binding protein 9 family
C3496_15940	COG0702	epimerase
C3496_15950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3496_15960	COG4166	transmembrane transport
C3496_15975	COG0406	alpha-ribazole phosphatase activity
C3496_15985	COG5337	Spore coat protein CotH
C3496_15990	COG1051	belongs to the nudix hydrolase family
C3496_15995	COG0586	Pfam SNARE associated Golgi protein
C3496_16000	COG2244	polysaccharide biosynthetic process
C3496_16010	COG0701	Predicted permease
C3496_16015	COG3689	TIGRFAM TIGR03943 family protein
C3496_16020	COG1607	acyl-coa hydrolase
C3496_16030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_16045	COG0702	epimerase
C3496_16050	COG2839	Protein conserved in bacteria
C3496_16055	COG1253	flavin adenine dinucleotide binding
C3496_16070	COG1114	Component of the transport system for branched-chain amino acids
C3496_16075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_16095	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_16105	COG1876	peptidase activity
C3496_16115	COG0154	amidase activity
C3496_16120	COG2211	Major facilitator Superfamily
C3496_16135	COG2368	4-hydroxyphenylacetate
C3496_16145	COG0196	riboflavin kinase activity
C3496_16160	COG0251	oxidation-reduction process
C3496_16170	COG3971	2-oxopent-4-enoate hydratase activity
C3496_16190	COG1942	4-Oxalocrotonate Tautomerase
C3496_16200	COG0561	phosphatase activity
C3496_16210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3496_16230	COG1819	glycosyl
C3496_16235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_16240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_16270	COG0456	acetyltransferase
C3496_16360	COG0582	viral genome integration into host DNA
C3496_16465	COG3874	Sporulation protein YtfJ
C3496_16490	COG2226	methyltransferase
C3496_16510	COG1082	Xylose isomerase domain protein TIM barrel
C3496_16515	COG0346	lactoylglutathione lyase activity
C3496_16525	COG0604	alcohol dehydrogenase
C3496_16530	COG1595	DNA-templated transcription, initiation
C3496_16555	COG0426	domain, Protein
C3496_16555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3496_16575	COG0386	Belongs to the glutathione peroxidase family
C3496_16580	COG1305	Transglutaminase-like
C3496_16585	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C3496_16590	COG0714	Associated with various cellular activities
C3496_16605	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C3496_16610	COG1140	nitrate reductase beta subunit
C3496_16615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C3496_16620	COG2181	nitrate reductase activity
C3496_16625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3496_16630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3496_16635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_16640	COG0303	'Molybdopterin
C3496_16645	COG0314	molybdopterin synthase activity
C3496_16655	COG2223	nitrite transmembrane transporter activity
C3496_16675	COG1648	precorrin-2 dehydrogenase activity
C3496_16685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3496_16685	COG1587	Uroporphyrinogen-III synthase
C3496_16690	COG2146	nitrite reductase [NAD(P)H] activity
C3496_16695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3496_16700	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C3496_16735	COG2359	stage V sporulation protein S
C3496_16780	COG1418	mRNA catabolic process
C3496_16785	COG0488	(ABC) transporter
C3496_16800	COG0629	single-stranded DNA binding
C3496_16805	COG1413	lyase activity
C3496_16820	COG2521	methyltransferase
C3496_16820	COG2136	Putative SAM-dependent methyltransferase
C3496_16875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3496_16885	COG0017	Asparaginyl-tRNA synthetase
C3496_16905	COG1674	ftsk spoiiie
C3496_17050	COG0733	neurotransmitter:sodium symporter activity
C3496_17075	COG2610	gluconate transmembrane transporter activity
C3496_17080	COG1454	alcohol dehydrogenase
C3496_17085	COG1794	racemase activity, acting on amino acids and derivatives
C3496_17095	COG0456	acetyltransferase
C3496_17100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C3496_17110	COG1131	(ABC) transporter
C3496_17115	COG4473	ABC transporter
C3496_17125	COG0546	phosphoglycolate phosphatase activity
C3496_17145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_17160	COG0768	penicillin binding
C3496_17170	COG0204	Acyl-transferase
C3496_17175	COG1272	protein, Hemolysin III
C3496_17185	COG0805	protein transport
C3496_17200	COG1307	EDD domain protein, DegV family
C3496_17210	COG1999	signal sequence binding
C3496_17215	COG0071	Belongs to the small heat shock protein (HSP20) family
C3496_17220	COG0367	asparagine synthase
C3496_17240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_17245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_17260	COG1335	isochorismatase
C3496_17265	COG1051	belongs to the nudix hydrolase family
C3496_17270	COG0071	Belongs to the small heat shock protein (HSP20) family
C3496_17275	COG0668	transmembrane transport
C3496_17280	COG2203	Gaf domain
C3496_17280	COG4585	Histidine kinase
C3496_17285	COG2197	response regulator
C3496_17290	COG1737	Transcriptional regulator
C3496_17295	COG1064	alcohol dehydrogenase
C3496_17350	COG1125	glycine betaine transport
C3496_17350	COG0517	IMP dehydrogenase activity
C3496_17355	COG1174	glycine betaine transport
C3496_17390	COG1253	flavin adenine dinucleotide binding
C3496_17395	COG1012	belongs to the aldehyde dehydrogenase family
C3496_17400	COG5506	Protein of unknown function (DUF1694)
C3496_17420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_17425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3496_17430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3496_17435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_17440	COG0456	acetyltransferase
C3496_17445	COG3829	transcription factor binding
C3496_17455	COG1509	lysine 2,3-aminomutase activity
C3496_17490	COG3064	Membrane
C3496_17490	COG4991	sh3 domain protein
C3496_17490	COG0515	serine threonine protein kinase
C3496_17495	COG4326	sporulation control protein
C3496_17500	COG0671	phosphoesterase, PA-phosphatase related
C3496_17505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3496_17510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_17590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_17635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_17635	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3496_17645	COG2814	Major facilitator Superfamily
C3496_17650	COG4841	protein insertion into membrane
C3496_17655	COG0372	Belongs to the citrate synthase family
C3496_17660	COG2079	MmgE PrpD family protein
C3496_17665	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C3496_17670	COG1960	acyl-CoA dehydrogenase activity
C3496_17675	COG2084	Dehydrogenase
C3496_17685	COG1280	lysine exporter protein (LysE YggA)
C3496_17690	COG1024	Enoyl-CoA hydratase
C3496_17705	COG0420	3'-5' exonuclease activity
C3496_17740	COG2223	nitrite transmembrane transporter activity
C3496_17750	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_17755	COG1169	isochorismate synthase
C3496_17760	COG1021	2,3-dihydroxybenzoate-AMP ligase
C3496_17765	COG1535	isochorismatase
C3496_17765	COG3433	isochorismatase activity
C3496_17770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3496_17775	COG3251	PFAM MbtH domain protein
C3496_17780	COG2814	Major facilitator Superfamily
C3496_17795	COG0776	regulation of translation
C3496_17805	COG2318	DinB family
C3496_17815	COG1115	amino acid carrier protein
C3496_17830	COG2329	Antibiotic biosynthesis monooxygenase
C3496_17835	COG1187	pseudouridine synthase activity
C3496_17840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3496_17845	COG1136	(ABC) transporter
C3496_17860	COG0596	Alpha beta hydrolase
C3496_17865	COG2814	Major facilitator Superfamily
C3496_17880	COG0028	Belongs to the TPP enzyme family
C3496_17960	COG1247	-acetyltransferase
C3496_17985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3496_18000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_18010	COG1278	Cold shock
C3496_18030	COG0010	Belongs to the arginase family
C3496_18035	COG0561	phosphatase activity
C3496_18045	COG0583	DNA-binding transcription factor activity
C3496_18050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3496_18065	COG0583	DNA-binding transcription factor activity
C3496_18070	COG2258	MOSC domain
C3496_18085	COG1132	(ABC) transporter
C3496_18090	COG1132	(ABC) transporter
C3496_18110	COG1396	sequence-specific DNA binding
C3496_18140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3496_18150	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C3496_18155	COG1595	DNA-templated transcription, initiation
C3496_18185	COG1649	PFAM Uncharacterised BCR, COG1649
C3496_18215	COG2971	BadF BadG BcrA BcrD
C3496_18225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C3496_18265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_18295	COG1309	transcriptional regulator
C3496_18310	COG1136	(ABC) transporter
C3496_18310	COG0577	efflux transmembrane transporter activity
C3496_18315	COG3615	Tellurite resistance protein tehB
C3496_18315	COG0500	methyltransferase
C3496_18325	COG3961	Belongs to the TPP enzyme family
C3496_18330	COG1846	Transcriptional regulator
C3496_18360	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3496_18375	COG0110	maltose O-acetyltransferase activity
C3496_18385	COG0768	penicillin binding
C3496_18390	COG1595	DNA-templated transcription, initiation
C3496_18400	COG0768	penicillin binding
C3496_18405	COG0768	penicillin binding
C3496_18410	COG2367	Beta-lactamase
C3496_18420	COG1609	Transcriptional regulator
C3496_18425	COG2814	Major facilitator Superfamily
C3496_18430	COG0673	inositol 2-dehydrogenase activity
C3496_18455	COG0191	fructose-bisphosphate aldolase activity
C3496_18460	COG3718	enzyme involved in inositol metabolism
C3496_18475	COG3773	Cell wall hydrolase
C3496_18490	COG2755	lipolytic protein G-D-S-L family
C3496_18490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3496_18510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_18555	COG1131	(ABC) transporter
C3496_18570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_18600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3496_18655	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_18665	COG1252	NADH dehydrogenase
C3496_18685	COG1131	(ABC) transporter
C3496_18695	COG1309	transcriptional regulator
C3496_18715	COG1960	acyl-CoA dehydrogenase activity
C3496_18720	COG0439	Biotin carboxylase
C3496_18725	COG0511	ligase activity, forming carbon-carbon bonds
C3496_18730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3496_18735	COG1024	Enoyl-CoA hydratase
C3496_18740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3496_18745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_18755	COG1247	-acetyltransferase
C3496_18760	COG0572	uridine kinase
C3496_18770	COG2318	DinB family
C3496_18775	COG1686	Belongs to the peptidase S11 family
C3496_18800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C3496_18805	COG2910	NAD(P)H-binding
C3496_18820	COG3227	Zinc metalloprotease (Elastase)
C3496_18825	COG2207	Transcriptional regulator
C3496_18870	COG0789	Transcriptional regulator
C3496_18890	COG2226	methyltransferase
C3496_18905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_18925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_18940	COG1063	alcohol dehydrogenase
C3496_18945	COG2323	membrane
C3496_18960	COG3386	PFAM SMP-30 Gluconolaconase
C3496_18970	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C3496_18975	COG3773	Cell wall hydrolase
C3496_18990	COG0745	RESPONSE REGULATOR receiver
C3496_18995	COG2205	protein histidine kinase activity
C3496_19000	COG0488	(ABC) transporter
C3496_19015	COG1136	(ABC) transporter
C3496_19020	COG0577	efflux transmembrane transporter activity
C3496_19040	COG0460	homoserine dehydrogenase
C3496_19045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_19055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3496_19155	COG2124	cytochrome p450
C3496_19190	COG0561	phosphatase activity
C3496_19200	COG5002	protein histidine kinase activity
C3496_19205	COG0768	penicillin binding
C3496_19210	COG1819	glycosyl
C3496_19215	COG1794	racemase activity, acting on amino acids and derivatives
C3496_19240	COG2205	protein histidine kinase activity
C3496_19250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_19255	COG0604	alcohol dehydrogenase
C3496_19260	COG0671	phosphoesterase, PA-phosphatase related
C3496_19265	COG0768	penicillin binding
C3496_19325	COG0693	protein deglycase activity
C3496_19350	COG0789	Transcriptional regulator
C3496_19360	COG2814	Major facilitator Superfamily
C3496_19380	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_19400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_19405	COG0697	spore germination
C3496_19425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_19435	COG2223	nitrite transmembrane transporter activity
C3496_19450	COG2816	NAD+ diphosphatase activity
C3496_19455	COG0592	DNA-directed DNA polymerase activity
C3496_19460	COG1051	belongs to the nudix hydrolase family
C3496_19495	COG3878	Protein conserved in bacteria
C3496_19515	COG4667	esterase of the alpha-beta hydrolase superfamily
C3496_19540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3496_19555	COG0322	excinuclease ABC activity
C3496_19600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_19620	COG1011	Hydrolase
C3496_19650	COG1523	belongs to the glycosyl hydrolase 13 family
C3496_19655	COG3227	Zinc metalloprotease (Elastase)
C3496_19675	COG0346	lactoylglutathione lyase activity
C3496_19680	COG0201	protein transport
C3496_19690	COG0697	spore germination
C3496_19695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_19735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_19750	COG2959	enzyme of heme biosynthesis
C3496_19785	COG1309	transcriptional regulator
C3496_19820	COG3284	Transcriptional regulator
C3496_19830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_19835	COG1349	DNA-binding transcription factor activity
C3496_19855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3496_19860	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_19865	COG0022	dehydrogenase e1 component
C3496_19870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_19880	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_19885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_19885	COG0456	acetyltransferase
C3496_19920	COG4176	ABC-type proline glycine betaine transport system permease component
C3496_19925	COG4175	Glycine betaine
C3496_19925	COG0517	IMP dehydrogenase activity
C3496_19950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C3496_19955	COG2153	protein acetylation
C3496_19960	COG3397	chitin binding
C3496_19965	COG1819	glycosyl
C3496_19985	COG2205	protein histidine kinase activity
C3496_19990	COG2226	methyltransferase
C3496_20030	COG3973	AAA domain
C3496_20050	COG0514	ATP-dependent DNA helicase (RecQ)
C3496_20080	COG4637	Psort location Cytoplasmic, score
C3496_20105	COG3397	chitin binding
C3496_20120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C3496_20125	COG1115	amino acid carrier protein
C3496_20130	COG1012	belongs to the aldehyde dehydrogenase family
C3496_20135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3496_20145	COG3938	Belongs to the proline racemase family
C3496_20150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_20190	COG0586	Pfam SNARE associated Golgi protein
C3496_20205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C3496_20215	COG4166	transmembrane transport
C3496_20225	COG4948	Mandelate Racemase Muconate Lactonizing
C3496_20275	COG2936	dipeptidyl-peptidase activity
C3496_20280	COG5002	protein histidine kinase activity
C3496_20285	COG0745	RESPONSE REGULATOR receiver
C3496_20315	COG1164	Oligoendopeptidase f
C3496_20320	COG0531	amino acid
C3496_20325	COG1522	sequence-specific DNA binding
C3496_20340	COG1307	EDD domain protein, DegV family
C3496_20370	COG2814	Major facilitator Superfamily
C3496_20375	COG1664	Polymer-forming cytoskeletal
C3496_20380	COG1664	Polymer-forming cytoskeletal
C3496_20385	COG0789	Transcriptional regulator
C3496_20390	COG4533	DNA binding
C3496_20395	COG0477	Major facilitator Superfamily
C3496_20395	COG2814	Major facilitator Superfamily
C3496_20415	COG2261	transglycosylase associated protein
C3496_20430	COG2226	methyltransferase
C3496_20470	COG0436	Aminotransferase
C3496_20475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3496_20485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C3496_20500	COG1131	(ABC) transporter
C3496_20555	COG0628	permease
C3496_20570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_20575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_20580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_20615	COG2746	aminoglycoside 3-N-acetyltransferase activity
C3496_20640	COG0697	spore germination
C3496_20645	COG2318	DinB family
C3496_20665	COG4912	Dna alkylation repair
C3496_20685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_20690	COG0861	Integral membrane protein TerC family
C3496_20695	COG1368	sulfuric ester hydrolase activity
C3496_20705	COG0488	(ABC) transporter
C3496_20715	COG2409	Drug exporters of the RND superfamily
C3496_20715	COG1033	growth of symbiont in host cell
C3496_20720	COG1309	transcriptional regulator
C3496_20735	COG0287	Prephenate dehydrogenase
C3496_20755	COG1605	Chorismate mutase
C3496_20755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C3496_20795	COG3584	3D domain protein
C3496_20795	COG1388	LysM domain
C3496_20805	COG2610	gluconate transmembrane transporter activity
C3496_20810	COG1024	Enoyl-CoA hydratase
C3496_20820	COG3290	protein histidine kinase activity
C3496_20820	COG3829	transcription factor binding
C3496_20835	COG1879	ABC-type sugar transport system periplasmic component
C3496_20845	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3496_20855	COG2390	Transcriptional regulator
C3496_20860	COG1070	Carbohydrate kinase
C3496_20895	COG2329	Antibiotic biosynthesis monooxygenase
C3496_20915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_20925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3496_20935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_20950	COG4187	Peptidase family M20/M25/M40
C3496_20955	COG1414	Transcriptional regulator
C3496_20960	COG0833	amino acid
C3496_20965	COG1690	Belongs to the RtcB family
C3496_20970	COG3239	Fatty acid desaturase
C3496_20975	COG1785	Belongs to the alkaline phosphatase family
C3496_20985	COG3655	Transcriptional regulator
C3496_21000	COG4377	Putative membrane peptidase family (DUF2324)
C3496_21010	COG3279	Response regulator of the LytR AlgR family
C3496_21020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_21025	COG0346	lactoylglutathione lyase activity
C3496_21050	COG0714	Associated with various cellular activities
C3496_21075	COG0463	Glycosyl transferase, family 2
C3496_21095	COG0463	Glycosyl transferase, family 2
C3496_21105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3496_21110	COG0753	catalase activity
C3496_21120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C3496_21130	COG1280	lysine exporter protein (LysE YggA)
C3496_21135	COG3403	YqcI/YcgG family
C3496_21170	COG0778	Nitroreductase
C3496_21175	COG1846	Transcriptional regulator
C3496_21200	COG4884	unkown
C3496_21200	COG3831	ATPase activity
C3496_21210	COG1136	(ABC) transporter
C3496_21240	COG0456	acetyltransferase
C3496_21260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_21305	COG0730	response to heat
C3496_21315	COG0833	amino acid
C3496_21325	COG4335	DNA alkylation repair
C3496_21330	COG4978	Transcriptional regulator
C3496_21330	COG0789	Transcriptional regulator
C3496_21360	COG0768	penicillin binding
C3496_21395	COG1984	allophanate hydrolase subunit 2
C3496_21400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C3496_21405	COG1414	Transcriptional regulator
C3496_21420	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_21425	COG0640	Transcriptional regulator
C3496_21440	COG1960	acyl-CoA dehydrogenase activity
C3496_21455	COG3314	Sporulation integral membrane protein YlbJ
C3496_21465	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C3496_21480	COG3848	Pyruvate phosphate dikinase
C3496_21480	COG0574	Belongs to the PEP-utilizing enzyme family
C3496_21490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_21495	COG5577	PFAM Coat F domain
C3496_21505	COG3403	YqcI/YcgG family
C3496_21510	COG1280	lysine exporter protein (LysE YggA)
C3496_21515	COG1113	amino acid transport
C3496_21545	COG1063	alcohol dehydrogenase
C3496_21555	COG1027	Aspartate ammonia-lyase
C3496_21560	COG0252	asparaginase activity
C3496_21565	COG1396	sequence-specific DNA binding
C3496_21570	COG2801	Transposase and inactivated derivatives
C3496_21575	COG0322	excinuclease ABC activity
C3496_21580	COG0531	amino acid
C3496_21585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_21595	COG0784	Response regulator, receiver
C3496_21600	COG4191	Histidine kinase
C3496_21610	COG1115	amino acid carrier protein
C3496_21640	COG0737	Belongs to the 5'-nucleotidase family
C3496_21645	COG0753	catalase activity
C3496_21650	COG2267	carboxylic ester hydrolase activity
C3496_21655	COG1335	isochorismatase
C3496_21675	COG0583	DNA-binding transcription factor activity
C3496_21755	COG0415	Belongs to the DNA photolyase family
C3496_21760	COG0288	reversible hydration of carbon dioxide
C3496_21770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3496_21775	COG5609	conserved protein (DUF2294)
C3496_21795	COG1575	Belongs to the MenA family. Type 1 subfamily
C3496_21800	COG2267	carboxylic ester hydrolase activity
C3496_21805	COG4641	Protein conserved in bacteria
C3496_21810	COG1136	(ABC) transporter
C3496_21815	COG0577	efflux transmembrane transporter activity
C3496_21865	COG0798	PFAM Bile acid sodium symporter
C3496_21870	COG0346	lactoylglutathione lyase activity
C3496_21875	COG0640	Transcriptional regulator
C3496_21890	COG0443	Heat shock 70 kDa protein
C3496_21905	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_21925	COG0346	lactoylglutathione lyase activity
C3496_21945	COG2169	Transcriptional regulator
C3496_21995	COG2814	Major facilitator Superfamily
C3496_22055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C3496_22080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_22085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3496_22095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_22100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C3496_22120	COG0577	efflux transmembrane transporter activity
C3496_22135	COG3850	Histidine kinase
C3496_22135	COG5002	protein histidine kinase activity
C3496_22145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_22150	COG2271	Major facilitator Superfamily
C3496_22155	COG1556	Lactate utilization protein
C3496_22160	COG1139	Iron-sulfur cluster binding protein
C3496_22170	COG0583	DNA-binding transcription factor activity
C3496_22190	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_22210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3496_22230	COG0662	Cupin 2, conserved barrel domain protein
C3496_22240	COG2207	Transcriptional regulator
C3496_22240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_22280	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3496_22280	COG3409	Peptidoglycan-binding domain 1 protein
C3496_22320	COG0477	Major facilitator Superfamily
C3496_22335	COG1846	Transcriptional regulator
C3496_22340	COG2814	Major facilitator Superfamily
C3496_22355	COG2076	Multidrug Resistance protein
C3496_22360	COG1309	transcriptional regulator
C3496_22370	COG2031	fatty acid transporter
C3496_22380	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_22415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3496_22430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C3496_22435	COG1288	antiporter activity
C3496_22455	COG0789	Transcriptional regulator
C3496_22505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C3496_22520	COG1733	regulation of RNA biosynthetic process
C3496_22525	COG0778	Nitroreductase
C3496_22550	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_22560	COG1131	(ABC) transporter
C3496_22590	COG1011	Hydrolase
C3496_22600	COG2365	Tyrosine phosphatase family
C3496_22630	COG0346	lactoylglutathione lyase activity
C3496_22635	COG1940	carbohydrate kinase activity
C3496_22640	COG0738	Major facilitator superfamily
C3496_22645	COG0110	maltose O-acetyltransferase activity
C3496_22655	COG1136	(ABC) transporter
C3496_22655	COG0577	efflux transmembrane transporter activity
C3496_22675	COG0628	permease
C3496_22695	COG2226	methyltransferase
C3496_22735	COG1253	flavin adenine dinucleotide binding
C3496_22740	COG0789	Transcriptional regulator
C3496_22750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3496_22780	COG0697	spore germination
C3496_22785	COG1357	PFAM Pentapeptide repeats (8 copies)
C3496_22790	COG3813	Protein conserved in bacteria
C3496_22795	COG2706	6-phosphogluconolactonase activity
C3496_22800	COG1070	Carbohydrate kinase
C3496_22810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C3496_22815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C3496_22825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3496_22830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3496_22835	COG0604	alcohol dehydrogenase
C3496_22840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_22860	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_22875	COG0840	transmembrane signaling receptor activity
C3496_22885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_22885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_22890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3496_22890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3496_22895	COG1733	regulation of RNA biosynthetic process
C3496_22920	COG0814	amino acid
C3496_22955	COG1393	Belongs to the ArsC family
C3496_22965	COG1733	regulation of RNA biosynthetic process
C3496_22970	COG2188	Transcriptional regulator
C3496_22975	COG0673	inositol 2-dehydrogenase activity
C3496_22980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C3496_22985	COG1733	regulation of RNA biosynthetic process
C3496_22990	COG1733	regulation of RNA biosynthetic process
C3496_23010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_23030	COG0384	phenazine biosynthesis protein PhzF
C3496_23040	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_23055	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_23060	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_23065	COG1733	regulation of RNA biosynthetic process
C3496_23085	COG1191	sigma factor activity
C3496_23100	COG1309	transcriptional regulator
C3496_23120	COG3152	Membrane
C3496_23150	COG1151	hydroxylamine reductase activity
C3496_23165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_23170	COG3409	Peptidoglycan-binding domain 1 protein
C3496_23170	COG3757	hydrolase, family 25
C3496_23205	COG2072	flavoprotein involved in K transport
C3496_23250	COG0714	Associated with various cellular activities
C3496_23290	COG0604	alcohol dehydrogenase
C3496_23295	COG1113	amino acid transport
C3496_23300	COG2814	Major facilitator Superfamily
C3496_23335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_23340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_23350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_23355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_23360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_23365	COG3739	integral membrane protein
C3496_23370	COG0384	phenazine biosynthesis protein PhzF
C3496_23405	COG0583	DNA-binding transcription factor activity
C3496_23415	COG2890	protein-(glutamine-N5) methyltransferase activity
C3496_23430	COG1193	negative regulation of DNA recombination
C3496_23445	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C3496_23450	COG1164	Oligoendopeptidase f
C3496_23455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_23480	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_23505	COG0640	Transcriptional regulator
C3496_23510	COG0604	alcohol dehydrogenase
C3496_23520	COG0457	Tetratricopeptide repeat
C3496_23530	COG2808	Putative FMN-binding domain
C3496_23545	COG0385	Bile acid
C3496_23550	COG0277	FAD linked oxidase domain protein
C3496_23590	COG1216	Glycosyl transferase, family 2
C3496_23595	COG1024	Enoyl-CoA hydratase
C3496_23605	COG1285	pathogenesis
C3496_23620	COG2514	catechol 2,3-dioxygenase activity
C3496_23625	COG2720	vancomycin resistance protein
C3496_23665	COG0716	FMN binding
C3496_23695	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_23705	COG0165	Argininosuccinate lyase
C3496_23720	COG4145	pantothenate transmembrane transporter activity
C3496_23730	COG1012	belongs to the aldehyde dehydrogenase family
C3496_23735	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_23745	COG1657	PFAM Prenyltransferase squalene oxidase
C3496_23750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C3496_23755	COG2962	Rard protein
C3496_23760	COG3326	Membrane
C3496_23775	COG0489	protein tyrosine kinase activity
C3496_23785	COG0314	molybdopterin synthase activity
C3496_23790	COG0303	'Molybdopterin
C3496_23795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_23800	COG2116	formate transmembrane transporter activity
C3496_23815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3496_23820	COG5609	conserved protein (DUF2294)
C3496_23825	COG2427	Protein of unknown function (DUF1641)
C3496_23830	COG3383	formate dehydrogenase (NAD+) activity
C3496_23840	COG0697	spore germination
C3496_23890	COG2226	methyltransferase
C3496_23900	COG4166	transmembrane transport
C3496_23905	COG4166	transmembrane transport
C3496_23910	COG1301	dicarboxylic acid transport
C3496_23915	COG1316	TRANSCRIPTIONal
C3496_23925	COG1595	DNA-templated transcription, initiation
C3496_23940	COG1131	(ABC) transporter
C3496_23950	COG0673	inositol 2-dehydrogenase activity
C3496_23955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3496_23960	COG0187	DNA topoisomerase II activity
C3496_23970	COG1832	CoA-binding protein
C3496_23975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_23980	COG0745	RESPONSE REGULATOR receiver
C3496_24000	COG4841	protein insertion into membrane
C3496_24005	COG0824	Thioesterase
C3496_24040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_24055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C3496_24085	COG2211	Major facilitator Superfamily
C3496_24095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3496_24110	COG0183	Belongs to the thiolase family
C3496_24115	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_24120	COG1268	BioY protein
C3496_24125	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_24140	COG1396	sequence-specific DNA binding
C3496_24190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_24205	COG5002	protein histidine kinase activity
C3496_24210	COG0400	carboxylic ester hydrolase activity
C3496_24215	COG0346	lactoylglutathione lyase activity
C3496_24220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_24225	COG0069	glutamate synthase activity
C3496_24230	COG1902	pentaerythritol trinitrate reductase activity
C3496_24235	COG1329	Transcriptional regulator
C3496_24240	COG0010	Belongs to the arginase family
C3496_24305	COG4846	Membrane protein involved in cytochrome C biogenesis
C3496_24310	COG0785	Cytochrome C biogenesis protein
C3496_24325	COG1473	amidohydrolase
C3496_24335	COG1131	(ABC) transporter
C3496_24345	COG0583	DNA-binding transcription factor activity
C3496_24355	COG1346	cytolysis
C3496_24370	COG0730	response to heat
C3496_24395	COG1132	(ABC) transporter
C3496_24400	COG1132	(ABC) transporter
C3496_24445	COG0737	Belongs to the 5'-nucleotidase family
C3496_24455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C3496_24475	COG1695	Transcriptional regulator
C3496_24490	COG1196	nuclear chromosome segregation
C3496_24490	COG0741	lytic transglycosylase activity
C3496_24490	COG0739	heme binding
C3496_24495	COG0741	lytic transglycosylase activity
C3496_24525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C3496_24530	COG0174	glutamine synthetase
C3496_24535	COG0789	Transcriptional regulator
C3496_24540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C3496_24545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3496_24550	COG2860	membrane
C3496_24555	COG0464	growth
C3496_24585	COG3584	3D domain protein
C3496_24585	COG1388	LysM domain
C3496_24595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3496_24595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3496_24595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_24600	COG1105	Belongs to the carbohydrate kinase PfkB family
C3496_24605	COG1349	DNA-binding transcription factor activity
C3496_24610	COG1979	alcohol dehydrogenase
C3496_24615	COG2322	membrane
C3496_24630	COG1113	amino acid transport
C3496_24650	COG1408	metallophosphoesterase
C3496_24655	COG2116	formate transmembrane transporter activity
C3496_24670	COG2217	Heavy metal translocating P-type atpase
C3496_24675	COG2608	mercury ion transmembrane transporter activity
C3496_24680	COG1937	Protein conserved in bacteria
C3496_24690	COG2819	hydrolase of the alpha beta superfamily
C3496_24695	COG1120	ATPase activity
C3496_24700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_24705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_24710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_24715	COG0708	Exodeoxyribonuclease III
C3496_24720	COG2169	Transcriptional regulator
C3496_24725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3496_24730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C3496_24740	COG2364	Membrane
C3496_24755	COG2267	carboxylic ester hydrolase activity
C3496_24760	COG0346	lactoylglutathione lyase activity
C3496_24765	COG3300	MHYT domain
C3496_24765	COG5001	Diguanylate cyclase
C3496_24785	COG1380	Effector of murein hydrolase LrgA
C3496_24790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_24795	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_24795	COG0596	Alpha beta hydrolase
C3496_24800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_24820	COG1404	Belongs to the peptidase S8 family
C3496_24825	COG3773	Cell wall hydrolase
C3496_24835	COG1368	sulfuric ester hydrolase activity
C3496_24840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_24875	COG0604	alcohol dehydrogenase
C3496_24875	COG3321	synthase
C3496_24890	COG2086	electron transfer activity
C3496_24895	COG1960	acyl-CoA dehydrogenase activity
C3496_24910	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_24935	COG1136	(ABC) transporter
C3496_24965	COG4550	Control of competence regulator ComK, YlbF/YmcA
C3496_24975	COG1013	pyruvate-flavodoxin oxidoreductase activity
C3496_24980	COG0674	pyruvate-flavodoxin oxidoreductase activity
C3496_24980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C3496_24990	COG2359	stage V sporulation protein S
C3496_24995	COG1692	metallophosphoesterase
C3496_25020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3496_25025	COG1426	Protein conserved in bacteria
C3496_25040	COG0300	oxidoreductase activity
C3496_25045	COG0612	Peptidase, M16
C3496_25050	COG0612	Peptidase, M16
C3496_25055	COG1079	Belongs to the binding-protein-dependent transport system permease family
C3496_25060	COG4603	Belongs to the binding-protein-dependent transport system permease family
C3496_25065	COG3845	ABC transporter
C3496_25070	COG1744	ABC transporter substrate-binding protein PnrA-like
C3496_25075	COG2188	Transcriptional regulator
C3496_25085	COG1674	ftsk spoiiie
C3496_25095	COG0740	serine-type endopeptidase activity
C3496_25100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_25115	COG0527	aspartate kinase activity
C3496_25120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3496_25125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3496_25150	COG4824	toxin secretion phage lysis holin
C3496_25210	COG0582	viral genome integration into host DNA
C3496_25245	COG0305	Participates in initiation and elongation during chromosome replication
C3496_25280	COG1396	sequence-specific DNA binding
C3496_25315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3496_25325	COG1873	PFAM PRC-barrel domain
C3496_25330	COG0612	Peptidase, M16
C3496_25335	COG0726	polysaccharide deacetylase
C3496_25350	COG0196	riboflavin kinase activity
C3496_25365	COG1550	Protein conserved in bacteria
C3496_25375	COG1358	cellular component organization or biogenesis
C3496_25380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C3496_25385	COG0195	Participates in both transcription termination and antitermination
C3496_25410	COG0750	zinc metalloprotease
C3496_25420	COG4589	Belongs to the CDS family
C3496_25435	COG0528	UMP kinase activity
C3496_25465	COG4974	Belongs to the 'phage' integrase family
C3496_25475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3496_25480	COG0758	DNA mediated transformation
C3496_25485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3496_25525	COG1837	Belongs to the UPF0109 family
C3496_25535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3496_25545	COG0552	protein localization to endoplasmic reticulum
C3496_25550	COG1196	nuclear chromosome segregation
C3496_25560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_25565	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_25570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3496_25585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3496_25590	COG1461	Dihydroxyacetone kinase
C3496_25595	COG1302	Protein conserved in bacteria
C3496_25610	COG1564	THIamine pyrophosphokinase
C3496_25615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3496_25625	COG0515	serine threonine protein kinase
C3496_25625	COG2815	serine threonine protein kinase
C3496_25630	COG0631	protein serine/threonine phosphatase activity
C3496_25640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C3496_25640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C3496_25650	COG0242	peptide deformylase activity
C3496_25655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3496_25660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3496_25680	COG1561	YicC-like family, N-terminal region
C3496_25685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C3496_25695	COG0006	proline dipeptidase activity
C3496_25715	COG3069	C4-dicarboxylate transmembrane transporter activity
C3496_25780	COG0564	pseudouridine synthase activity
C3496_25800	COG3599	regulation of cell shape
C3496_25805	COG2302	S4 RNA-binding domain
C3496_25810	COG0762	integral membrane protein
C3496_25820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C3496_25825	COG1496	oxidoreductase activity
C3496_25830	COG1873	PFAM PRC-barrel domain
C3496_25835	COG1191	sigma factor activity
C3496_25840	COG1191	sigma factor activity
C3496_25850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C3496_25855	COG0849	cell division
C3496_25860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C3496_25875	COG0772	Belongs to the SEDS family
C3496_25890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3496_25895	COG0768	penicillin binding
C3496_25900	COG0768	penicillin binding
C3496_25905	COG4839	cell division protein FtsL
C3496_25920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3496_25935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C3496_25940	COG1399	metal-binding, possibly nucleic acid-binding protein
C3496_25950	COG3480	Lon protease (S16) C-terminal proteolytic domain
C3496_25955	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3496_25960	COG3314	Sporulation integral membrane protein YlbJ
C3496_25970	COG0742	ribosomal rna small subunit methyltransferase
C3496_25985	COG3679	Belongs to the UPF0342 family
C3496_25990	COG0406	alpha-ribazole phosphatase activity
C3496_26005	COG2340	Cysteine-rich secretory protein family
C3496_26020	COG3336	cytochrome c oxidase
C3496_26055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C3496_26065	COG0772	Belongs to the SEDS family
C3496_26075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3496_26080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C3496_26090	COG4896	Protein conserved in bacteria
C3496_26105	COG1217	gtp-binding protein TYPA
C3496_26115	COG0483	inositol monophosphate 1-phosphatase activity
C3496_26135	COG1982	Orn Lys Arg decarboxylase major
C3496_26185	COG0022	dehydrogenase e1 component
C3496_26190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_26200	COG0242	peptide deformylase activity
C3496_26205	COG0561	phosphatase activity
C3496_26220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_26225	COG0569	domain protein
C3496_26245	COG0583	DNA-binding transcription factor activity
C3496_26250	COG0517	IMP dehydrogenase activity
C3496_26260	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C3496_26270	COG4703	Protein of unknown function (DUF1797)
C3496_26285	COG2200	EAL domain
C3496_26290	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_26295	COG1408	metallophosphoesterase
C3496_26310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C3496_26350	COG2814	Major facilitator Superfamily
C3496_26375	COG3209	COG3209 Rhs family protein
C3496_26390	COG2205	protein histidine kinase activity
C3496_26400	COG0436	Aminotransferase
C3496_26405	COG1609	Transcriptional regulator
C3496_26410	COG3833	ABC-type maltose transport systems, permease component
C3496_26415	COG1175	transmembrane transport
C3496_26420	COG2182	Extracellular solute-binding protein
C3496_26430	COG0366	Alpha amylase catalytic
C3496_26435	COG3842	ATPase activity
C3496_26480	COG0183	Belongs to the thiolase family
C3496_26515	COG1695	Transcriptional regulator
C3496_26520	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_26540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3496_26545	COG0436	Aminotransferase
C3496_26580	COG2084	Dehydrogenase
C3496_26590	COG2199	diguanylate cyclase activity
C3496_26595	COG0778	Nitroreductase
C3496_26620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_26620	COG2190	(PTS) system
C3496_26620	COG1263	PTS System
C3496_26625	COG3711	transcriptional antiterminator
C3496_26635	COG2188	Transcriptional regulator
C3496_26645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C3496_26675	COG1547	Domain of unknown function (DUF309)
C3496_26680	COG0456	acetyltransferase
C3496_26690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3496_26695	COG4086	secreted protein
C3496_26700	COG0561	phosphatase activity
C3496_26705	COG0697	spore germination
C3496_26720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_26745	COG0733	neurotransmitter:sodium symporter activity
C3496_26765	COG1686	Belongs to the peptidase S11 family
C3496_26775	COG1725	Transcriptional regulator
C3496_26780	COG1131	(ABC) transporter
C3496_26800	COG1846	Transcriptional regulator
C3496_26815	COG0598	Magnesium transport protein CorA
C3496_26840	COG4974	Belongs to the 'phage' integrase family
C3496_26850	COG0735	belongs to the Fur family
C3496_26855	COG1300	Membrane
C3496_26875	COG0667	Aldo Keto reductase
C3496_26880	COG0656	L-ascorbic acid biosynthetic process
C3496_26885	COG0456	acetyltransferase
C3496_26885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_26895	COG4085	toxin activity
C3496_26895	COG1525	nuclease
C3496_26895	COG0737	Belongs to the 5'-nucleotidase family
C3496_26905	COG0596	Alpha beta hydrolase
C3496_26910	COG2056	Na+-H+ antiporter family
C3496_26915	COG1609	Transcriptional regulator
C3496_26920	COG0456	acetyltransferase
C3496_26925	COG1073	alpha beta
C3496_26940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_26940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_26945	COG0307	riboflavin synthase, alpha
C3496_26970	COG4106	trans-aconitate 2-methyltransferase activity
C3496_26975	COG1073	alpha beta
C3496_26975	COG2226	methyltransferase
C3496_26990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_27005	COG1757	Na H antiporter
C3496_27010	COG0737	Belongs to the 5'-nucleotidase family
C3496_27020	COG1522	sequence-specific DNA binding
C3496_27040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3496_27065	COG0300	oxidoreductase activity
C3496_27070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_27075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_27080	COG1760	l-serine dehydratase
C3496_27085	COG1760	l-serine dehydratase
C3496_27120	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3496_27125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_27140	COG1376	ErfK ybiS ycfS ynhG family protein
C3496_27145	COG4129	membrane
C3496_27150	COG1126	abc transporter atp-binding protein
C3496_27155	COG0765	amino acid transport
C3496_27160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_27185	COG2323	membrane
C3496_27190	COG0772	Belongs to the SEDS family
C3496_27200	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_27205	COG0022	dehydrogenase e1 component
C3496_27210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_27215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3496_27230	COG0280	phosphate acetyltransferase
C3496_27240	COG3290	protein histidine kinase activity
C3496_27240	COG3829	transcription factor binding
C3496_27250	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_27255	COG3093	addiction module antidote protein HigA
C3496_27265	COG0745	RESPONSE REGULATOR receiver
C3496_27275	COG0750	zinc metalloprotease
C3496_27280	COG0497	DNA recombination
C3496_27290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C3496_27300	COG0142	geranyltranstransferase activity
C3496_27325	COG1302	Protein conserved in bacteria
C3496_27330	COG0439	Biotin carboxylase
C3496_27335	COG0511	ligase activity, forming carbon-carbon bonds
C3496_27380	COG3854	ATPases associated with a variety of cellular activities
C3496_27405	COG0006	proline dipeptidase activity
C3496_27420	COG3872	metal-dependent enzyme
C3496_27430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3496_27465	COG0095	Lipoate-protein ligase
C3496_27470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_27475	COG1609	Transcriptional regulator
C3496_27485	COG2076	Multidrug Resistance protein
C3496_27490	COG2076	Multidrug Resistance protein
C3496_27530	COG1131	(ABC) transporter
C3496_27535	COG1725	Transcriptional regulator
C3496_27570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_27630	COG4970	Tfp pilus assembly protein FimT
C3496_27640	COG1459	type II secretion system
C3496_27645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3496_27695	COG1410	methionine synthase
C3496_27695	COG0646	methionine synthase
C3496_27700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3496_27700	COG0646	methionine synthase
C3496_27705	COG0626	cystathionine gamma-synthase activity
C3496_27710	COG0626	cystathionine gamma-synthase activity
C3496_27730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_27740	COG1940	carbohydrate kinase activity
C3496_27745	COG4483	Protein conserved in bacteria
C3496_27750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3496_27755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C3496_27760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3496_27765	COG0704	Plays a role in the regulation of phosphate uptake
C3496_27775	COG0581	inorganic phosphate transmembrane transporter activity
C3496_27780	COG0573	inorganic phosphate transmembrane transporter activity
C3496_27785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3496_27790	COG0768	penicillin binding
C3496_27795	COG0477	Major facilitator Superfamily
C3496_27800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_27825	COG0735	belongs to the Fur family
C3496_27830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3496_27835	COG1121	(ABC) transporter
C3496_27840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_27870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3496_27875	COG2384	SAM-dependent methyltransferase
C3496_27880	COG2010	Cytochrome c
C3496_27885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3496_27890	COG0358	DNA primase activity
C3496_27910	COG0517	IMP dehydrogenase activity
C3496_27925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C3496_27930	COG0295	cytidine deaminase activity
C3496_27935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C3496_27945	COG1480	7TM receptor with intracellular HD hydrolase
C3496_27950	COG1702	phosphate starvation-inducible protein PhoH
C3496_27970	COG1610	YqeY-like protein
C3496_27975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C3496_27985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3496_27990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3496_28020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3496_28025	COG1733	regulation of RNA biosynthetic process
C3496_28050	COG1466	dna polymerase III delta subunit
C3496_28060	COG0658	competence protein
C3496_28060	COG2333	competence protein COMEC
C3496_28065	COG2131	deaminase
C3496_28070	COG1596	polysaccharide export
C3496_28070	COG1555	photosystem II stabilization
C3496_28075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_28080	COG2226	methyltransferase
C3496_28085	COG0799	negative regulation of ribosome biogenesis
C3496_28090	COG1713	HD superfamily hydrolase involved in NAD metabolism
C3496_28100	COG1534	Rna-binding protein
C3496_28110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C3496_28115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C3496_28140	COG1595	DNA-templated transcription, initiation
C3496_28150	COG0778	Nitroreductase
C3496_28155	COG2357	RelA SpoT domain protein
C3496_28165	COG1785	Belongs to the alkaline phosphatase family
C3496_28175	COG2267	carboxylic ester hydrolase activity
C3496_28210	COG1404	Belongs to the peptidase S8 family
C3496_28215	COG3186	Phenylalanine-4-hydroxylase
C3496_28225	COG2514	catechol 2,3-dioxygenase activity
C3496_28230	COG2259	Doxx family
C3496_28270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_28280	COG1012	belongs to the aldehyde dehydrogenase family
C3496_28280	COG1454	alcohol dehydrogenase
C3496_28285	COG0626	cystathionine gamma-synthase activity
C3496_28290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_28315	COG0768	penicillin binding
C3496_28335	COG0826	peptidase U32
C3496_28340	COG0826	peptidase U32
C3496_28345	COG4122	O-methyltransferase activity
C3496_28350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3496_28380	COG0628	permease
C3496_28400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3496_28415	COG1104	cysteine desulfurase activity
C3496_28420	COG1959	2 iron, 2 sulfur cluster binding
C3496_28425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C3496_28440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3496_28470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance