locus-tag	class	description
HYU01_00015	COG0592	DNA-directed DNA polymerase activity
HYU01_00020	COG2501	S4 domain
HYU01_00030	COG0187	DNA topoisomerase II activity
HYU01_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HYU01_00070	COG0517	IMP dehydrogenase activity
HYU01_00070	COG0516	GMP reductase activity
HYU01_00075	COG1686	Belongs to the peptidase S11 family
HYU01_00105	COG1428	Deoxynucleoside kinase
HYU01_00110	COG1428	Deoxynucleoside kinase
HYU01_00115	COG1335	isochorismatase
HYU01_00120	COG0590	tRNA wobble adenosine to inosine editing
HYU01_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HYU01_00180	COG1982	Orn Lys Arg decarboxylase major
HYU01_00190	COG0470	DNA polymerase III
HYU01_00195	COG1774	PSP1 C-terminal conserved region
HYU01_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HYU01_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HYU01_00220	COG2002	toxin-antitoxin pair type II binding
HYU01_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_00230	COG0084	hydrolase, TatD family'
HYU01_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HYU01_00250	COG4466	Protein conserved in bacteria
HYU01_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HYU01_00270	COG0251	oxidation-reduction process
HYU01_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HYU01_00290	COG0193	aminoacyl-tRNA hydrolase activity
HYU01_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HYU01_00305	COG2002	toxin-antitoxin pair type II binding
HYU01_00310	COG2244	polysaccharide biosynthetic process
HYU01_00315	COG3956	TIGRFAM MazG family protein
HYU01_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HYU01_00340	COG1098	S1 RNA binding domain
HYU01_00355	COG2208	phosphoserine phosphatase activity
HYU01_00360	COG0037	tRNA processing
HYU01_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HYU01_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HYU01_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HYU01_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
HYU01_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HYU01_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HYU01_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HYU01_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HYU01_00420	COG1396	sequence-specific DNA binding
HYU01_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HYU01_00455	COG3880	PFAM UvrB UvrC protein
HYU01_00465	COG0542	response to heat
HYU01_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HYU01_00480	COG4956	integral membrane protein (PIN domain superfamily)
HYU01_00500	COG1045	serine acetyltransferase
HYU01_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HYU01_00520	COG3688	RNA-binding protein containing a PIN domain
HYU01_00530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HYU01_00535	COG0250	Participates in transcription elongation, termination and antitermination
HYU01_00560	COG2813	Specifically methylates the guanine in position
HYU01_00570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HYU01_00575	COG1358	cellular component organization or biogenesis
HYU01_00680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HYU01_00705	COG0201	protein transport
HYU01_00715	COG0024	Methionine aminopeptidase
HYU01_00725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HYU01_00755	COG1122	ATPase activity
HYU01_00760	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HYU01_00765	COG0101	tRNA pseudouridine synthase activity
HYU01_00785	COG0860	N-Acetylmuramoyl-L-alanine amidase
HYU01_00790	COG0489	protein tyrosine kinase activity
HYU01_00800	COG2194	sulfuric ester hydrolase activity
HYU01_00805	COG0726	polysaccharide deacetylase
HYU01_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HYU01_00895	COG4856	YbbR-like protein
HYU01_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HYU01_00915	COG0596	Alpha beta hydrolase
HYU01_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HYU01_00940	COG0823	Involved in the tonB-independent uptake of proteins
HYU01_00940	COG1506	peptidase
HYU01_00940	COG4946	Tricorn protease homolog
HYU01_00975	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_00980	COG2011	ABC-type metal ion transport system permease component
HYU01_00985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HYU01_00990	COG1464	Belongs to the NlpA lipoprotein family
HYU01_01010	COG2271	Major facilitator Superfamily
HYU01_01020	COG2814	Major facilitator Superfamily
HYU01_01035	COG0601	transmembrane transport
HYU01_01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HYU01_01045	COG0444	Belongs to the ABC transporter superfamily
HYU01_01050	COG4608	Belongs to the ABC transporter superfamily
HYU01_01055	COG4166	transmembrane transport
HYU01_01065	COG2207	Transcriptional regulator
HYU01_01080	COG4166	transmembrane transport
HYU01_01085	COG4166	transmembrane transport
HYU01_01090	COG0656	L-ascorbic acid biosynthetic process
HYU01_01095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HYU01_01115	COG4149	molybdate abc transporter
HYU01_01120	COG0725	ABC transporter, periplasmic molybdate-binding protein
HYU01_01125	COG1910	domain protein
HYU01_01140	COG0583	DNA-binding transcription factor activity
HYU01_01145	COG0697	spore germination
HYU01_01160	COG0204	Acyl-transferase
HYU01_01175	COG1609	Transcriptional regulator
HYU01_01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_01200	COG0084	hydrolase, TatD family'
HYU01_01205	COG5298	Protein conserved in bacteria
HYU01_01230	COG0488	(ABC) transporter
HYU01_01245	COG0747	negative chemotaxis
HYU01_01250	COG0601	transmembrane transport
HYU01_01260	COG0444	Belongs to the ABC transporter superfamily
HYU01_01265	COG4608	Belongs to the ABC transporter superfamily
HYU01_01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HYU01_01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
HYU01_01300	COG2814	Major facilitator Superfamily
HYU01_01310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HYU01_01320	COG4294	response to UV
HYU01_01325	COG0705	Rhomboid family
HYU01_01325	COG0457	Tetratricopeptide repeat
HYU01_01335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HYU01_01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HYU01_01350	COG0864	Transcriptional regulator
HYU01_01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
HYU01_01360	COG2183	response to ionizing radiation
HYU01_01455	COG0802	atpase or kinase
HYU01_01460	COG1214	PFAM Peptidase M22, glycoprotease
HYU01_01465	COG0456	acetyltransferase
HYU01_01470	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HYU01_01475	COG0488	(ABC) transporter
HYU01_01490	COG1266	CAAX protease self-immunity
HYU01_01510	COG2252	PERMEase
HYU01_01520	COG5002	protein histidine kinase activity
HYU01_01540	COG1968	undecaprenyl-diphosphatase activity
HYU01_01555	COG2205	protein histidine kinase activity
HYU01_01560	COG0745	RESPONSE REGULATOR receiver
HYU01_01580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HYU01_01585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HYU01_01590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HYU01_01600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HYU01_01615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HYU01_01625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HYU01_01635	COG0151	Belongs to the GarS family
HYU01_01660	COG0210	DNA helicase
HYU01_01670	COG4851	CamS sex pheromone cAM373 precursor
HYU01_01690	COG1335	isochorismatase
HYU01_01695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HYU01_01700	COG2011	ABC-type metal ion transport system permease component
HYU01_01705	COG1464	Belongs to the NlpA lipoprotein family
HYU01_01720	COG1846	Transcriptional regulator
HYU01_01745	COG1597	lipid kinase activity
HYU01_01750	COG0546	phosphoglycolate phosphatase activity
HYU01_01755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HYU01_01765	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_01770	COG2076	Multidrug Resistance protein
HYU01_01775	COG2309	aminopeptidase activity
HYU01_01790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_01795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HYU01_01800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HYU01_01810	COG4807	Protein conserved in bacteria
HYU01_01840	COG1473	amidohydrolase
HYU01_01855	COG0450	alkyl hydroperoxide reductase
HYU01_01860	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HYU01_01870	COG0235	Class ii aldolase
HYU01_01875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_01880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_01885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_01900	COG0166	Belongs to the GPI family
HYU01_01940	COG5002	protein histidine kinase activity
HYU01_01960	COG3541	Predicted nucleotidyltransferase
HYU01_01965	COG2814	Major facilitator Superfamily
HYU01_01970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HYU01_01970	COG0723	plastoquinol--plastocyanin reductase activity
HYU01_01980	COG0765	amino acid transport
HYU01_01985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HYU01_02005	COG0840	transmembrane signaling receptor activity
HYU01_02010	COG0366	Alpha amylase catalytic
HYU01_02015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_02015	COG2190	(PTS) system
HYU01_02015	COG1263	PTS System
HYU01_02045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HYU01_02060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HYU01_02070	COG1116	anion transmembrane transporter activity
HYU01_02075	COG0488	(ABC) transporter
HYU01_02120	COG2270	Major facilitator Superfamily
HYU01_02135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HYU01_02150	COG2310	stress, protein
HYU01_02155	COG2310	stress, protein
HYU01_02160	COG2310	stress, protein
HYU01_02165	COG0861	Integral membrane protein TerC family
HYU01_02175	COG3853	Toxic anion resistance protein (TelA)
HYU01_02190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HYU01_02200	COG1295	ribonuclease BN
HYU01_02210	COG2217	Heavy metal translocating P-type atpase
HYU01_02215	COG0697	spore germination
HYU01_02235	COG0586	Pfam SNARE associated Golgi protein
HYU01_02250	COG3871	stress protein (general stress protein 26)
HYU01_02255	COG0387	Pfam Sodium calcium exchanger
HYU01_02265	COG0535	radical SAM domain protein
HYU01_02290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HYU01_02295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HYU01_02300	COG0582	viral genome integration into host DNA
HYU01_02315	COG1396	sequence-specific DNA binding
HYU01_02335	COG1396	sequence-specific DNA binding
HYU01_02370	COG1484	DNA-dependent DNA replication
HYU01_02475	COG0582	viral genome integration into host DNA
HYU01_02480	COG0582	viral genome integration into host DNA
HYU01_02610	COG0101	tRNA pseudouridine synthase activity
HYU01_02620	COG3829	transcription factor binding
HYU01_02630	COG0833	amino acid
HYU01_02635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HYU01_02660	COG2066	Belongs to the glutaminase family
HYU01_02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_02665	COG1263	PTS System
HYU01_02670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HYU01_02685	COG0463	Glycosyl transferase, family 2
HYU01_02700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HYU01_02700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HYU01_02715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HYU01_02735	COG1228	amidohydrolase
HYU01_02740	COG1090	epimerase
HYU01_02770	COG1988	membrane-bound metal-dependent
HYU01_02775	COG1194	a g-specific adenine glycosylase
HYU01_02800	COG1132	(ABC) transporter
HYU01_02805	COG4129	membrane
HYU01_02810	COG0067	glutamate synthase
HYU01_02810	COG0069	glutamate synthase activity
HYU01_02810	COG0070	glutamate synthase
HYU01_02820	COG4555	ABC transporter
HYU01_02840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HYU01_02845	COG0735	belongs to the Fur family
HYU01_02960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HYU01_02965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HYU01_02975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HYU01_02985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HYU01_03000	COG2766	serine protein kinase
HYU01_03020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HYU01_03030	COG1585	Membrane protein implicated in regulation of membrane protease activity
HYU01_03035	COG2268	Band 7 protein
HYU01_03045	COG3290	protein histidine kinase activity
HYU01_03050	COG4565	transcriptional regulatory protein
HYU01_03055	COG2851	Citrate transporter
HYU01_03075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HYU01_03080	COG3842	ATPase activity
HYU01_03085	COG1175	transmembrane transport
HYU01_03090	COG0395	ABC-type sugar transport system, permease component
HYU01_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HYU01_03110	COG0745	RESPONSE REGULATOR receiver
HYU01_03115	COG5002	protein histidine kinase activity
HYU01_03125	COG4990	cell redox homeostasis
HYU01_03135	COG3290	protein histidine kinase activity
HYU01_03140	COG4565	transcriptional regulatory protein
HYU01_03145	COG3493	citrate carrier protein
HYU01_03150	COG0281	malic enzyme
HYU01_03170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_03180	COG5002	protein histidine kinase activity
HYU01_03185	COG0745	RESPONSE REGULATOR receiver
HYU01_03200	COG0456	acetyltransferase
HYU01_03200	COG0454	-acetyltransferase
HYU01_03205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HYU01_03210	COG3383	formate dehydrogenase (NAD+) activity
HYU01_03220	COG2427	Protein of unknown function (DUF1641)
HYU01_03235	COG0531	amino acid
HYU01_03240	COG0640	Transcriptional regulator
HYU01_03245	COG2217	Heavy metal translocating P-type atpase
HYU01_03250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HYU01_03265	COG3227	Zinc metalloprotease (Elastase)
HYU01_03285	COG2720	vancomycin resistance protein
HYU01_03290	COG1316	TRANSCRIPTIONal
HYU01_03295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_03300	COG0346	lactoylglutathione lyase activity
HYU01_03305	COG1253	flavin adenine dinucleotide binding
HYU01_03310	COG1027	Aspartate ammonia-lyase
HYU01_03315	COG1620	l-lactate permease
HYU01_03330	COG3104	oligopeptide transport
HYU01_03335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_03340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_03345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_03355	COG2226	methyltransferase
HYU01_03360	COG0156	8-amino-7-oxononanoate synthase activity
HYU01_03365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HYU01_03375	COG4548	von Willebrand factor, type A
HYU01_03380	COG0714	Associated with various cellular activities
HYU01_03385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HYU01_03405	COG0531	amino acid
HYU01_03410	COG2188	Transcriptional regulator
HYU01_03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_03415	COG1263	PTS System
HYU01_03420	COG0366	Alpha amylase catalytic
HYU01_03435	COG0697	spore germination
HYU01_03445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HYU01_03450	COG1115	amino acid carrier protein
HYU01_03455	COG1126	abc transporter atp-binding protein
HYU01_03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HYU01_03465	COG0765	amino acid transport
HYU01_03470	COG0765	amino acid transport
HYU01_03475	COG0833	amino acid
HYU01_03500	COG2378	regulation of single-species biofilm formation
HYU01_03505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HYU01_03510	COG5002	protein histidine kinase activity
HYU01_03525	COG0659	secondary active sulfate transmembrane transporter activity
HYU01_03540	COG0747	negative chemotaxis
HYU01_03550	COG0601	transmembrane transport
HYU01_03555	COG4608	Belongs to the ABC transporter superfamily
HYU01_03565	COG2271	Major facilitator Superfamily
HYU01_03570	COG1846	Transcriptional regulator
HYU01_03575	COG0477	Major facilitator Superfamily
HYU01_03580	COG0477	Major facilitator Superfamily
HYU01_03585	COG1609	Transcriptional regulator
HYU01_03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HYU01_03600	COG1129	ABC transporter
HYU01_03605	COG1172	Belongs to the binding-protein-dependent transport system permease family
HYU01_03610	COG1879	ABC-type sugar transport system periplasmic component
HYU01_03615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HYU01_03635	COG1063	alcohol dehydrogenase
HYU01_03650	COG3568	Endonuclease Exonuclease Phosphatase
HYU01_03675	COG1968	undecaprenyl-diphosphatase activity
HYU01_03680	COG0840	transmembrane signaling receptor activity
HYU01_03685	COG3584	3D domain protein
HYU01_03685	COG1388	LysM domain
HYU01_03690	COG1476	TRANSCRIPTIONal
HYU01_03705	COG3104	oligopeptide transport
HYU01_03710	COG1114	Component of the transport system for branched-chain amino acids
HYU01_03725	COG1113	amino acid transport
HYU01_03730	COG2252	PERMEase
HYU01_03755	COG0475	glutathione-regulated potassium exporter activity
HYU01_03755	COG0569	domain protein
HYU01_03770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HYU01_03775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HYU01_03780	COG4990	cell redox homeostasis
HYU01_03795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HYU01_03800	COG0697	spore germination
HYU01_03805	COG0531	amino acid
HYU01_03820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HYU01_03825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HYU01_03830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HYU01_03830	COG1918	ferrous iron import across plasma membrane
HYU01_03835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HYU01_03840	COG0573	inorganic phosphate transmembrane transporter activity
HYU01_03845	COG0581	inorganic phosphate transmembrane transporter activity
HYU01_03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HYU01_03895	COG0544	peptidyl-prolyl cis-trans isomerase activity
HYU01_03975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HYU01_03995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HYU01_04000	COG1116	anion transmembrane transporter activity
HYU01_04005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HYU01_04010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HYU01_04015	COG0352	thiamine-phosphate diphosphorylase activity
HYU01_04020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HYU01_04025	COG2104	thiamine diphosphate biosynthetic process
HYU01_04035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HYU01_04040	COG0351	phosphomethylpyrimidine kinase
HYU01_04085	COG2205	protein histidine kinase activity
HYU01_04090	COG2814	Major facilitator Superfamily
HYU01_04095	COG1846	Transcriptional regulator
HYU01_04110	COG2252	PERMEase
HYU01_04115	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_04120	COG1376	ErfK ybiS ycfS ynhG family protein
HYU01_04130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HYU01_04135	COG1621	beta-fructofuranosidase activity
HYU01_04140	COG1263	PTS System
HYU01_04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_04145	COG1609	Transcriptional regulator
HYU01_04155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HYU01_04160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HYU01_04195	COG0778	Nitroreductase
HYU01_04200	COG2719	SpoVR family
HYU01_04230	COG0446	pyridine nucleotide-disulphide oxidoreductase
HYU01_04235	COG1937	Protein conserved in bacteria
HYU01_04240	COG0425	Belongs to the sulfur carrier protein TusA family
HYU01_04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_04250	COG0425	Belongs to the sulfur carrier protein TusA family
HYU01_04255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_04265	COG2210	Belongs to the sulfur carrier protein TusA family
HYU01_04270	COG0730	response to heat
HYU01_04280	COG1316	TRANSCRIPTIONal
HYU01_04285	COG0604	alcohol dehydrogenase
HYU01_04290	COG1283	sodium-dependent phosphate transmembrane transporter activity
HYU01_04305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HYU01_04305	COG3711	transcriptional antiterminator
HYU01_04310	COG1447	Phosphotransferase system cellobiose-specific component IIA
HYU01_04315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HYU01_04335	COG3584	3D domain protein
HYU01_04335	COG1388	LysM domain
HYU01_04340	COG0577	efflux transmembrane transporter activity
HYU01_04345	COG1136	(ABC) transporter
HYU01_04355	COG5522	Integral membrane protein (intg_mem_TP0381)
HYU01_04370	COG1114	Component of the transport system for branched-chain amino acids
HYU01_04375	COG3546	catalase activity
HYU01_04410	COG0586	Pfam SNARE associated Golgi protein
HYU01_04445	COG0531	amino acid
HYU01_04455	COG0475	glutathione-regulated potassium exporter activity
HYU01_04465	COG1737	Transcriptional regulator
HYU01_04475	COG1263	PTS System
HYU01_04475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_04485	COG2259	Doxx family
HYU01_04500	COG0697	spore germination
HYU01_04505	COG1522	sequence-specific DNA binding
HYU01_04515	COG2076	Multidrug Resistance protein
HYU01_04520	COG2076	Multidrug Resistance protein
HYU01_04525	COG1309	transcriptional regulator
HYU01_04530	COG2814	Major facilitator Superfamily
HYU01_04535	COG1733	regulation of RNA biosynthetic process
HYU01_04545	COG2249	NAD(P)H dehydrogenase (quinone) activity
HYU01_04550	COG4533	DNA binding
HYU01_04555	COG2211	Major facilitator Superfamily
HYU01_04565	COG0693	protein deglycase activity
HYU01_04570	COG0753	catalase activity
HYU01_04570	COG0693	protein deglycase activity
HYU01_04580	COG0531	amino acid
HYU01_04585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HYU01_04595	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_04605	COG1132	(ABC) transporter
HYU01_04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HYU01_04625	COG0765	amino acid transport
HYU01_04630	COG1126	abc transporter atp-binding protein
HYU01_04645	COG0189	ligase activity
HYU01_04675	COG0028	Belongs to the TPP enzyme family
HYU01_04680	COG3527	Alpha-acetolactate decarboxylase
HYU01_04695	COG0561	phosphatase activity
HYU01_04710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HYU01_04725	COG0659	secondary active sulfate transmembrane transporter activity
HYU01_04745	COG0653	protein targeting
HYU01_04750	COG2244	polysaccharide biosynthetic process
HYU01_04760	COG0860	N-Acetylmuramoyl-L-alanine amidase
HYU01_04765	COG4196	transglutaminase domain protein
HYU01_04780	COG1696	Membrane protein involved in D-alanine export
HYU01_04795	COG1024	Enoyl-CoA hydratase
HYU01_04815	COG1363	Peptidase, m42
HYU01_04835	COG3938	Belongs to the proline racemase family
HYU01_04875	COG0601	transmembrane transport
HYU01_04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HYU01_04890	COG4608	Belongs to the ABC transporter superfamily
HYU01_04925	COG0477	Major facilitator Superfamily
HYU01_04930	COG3290	protein histidine kinase activity
HYU01_04935	COG4565	transcriptional regulatory protein
HYU01_04940	COG3181	Tripartite tricarboxylate transporter family receptor
HYU01_04970	COG0789	Transcriptional regulator
HYU01_04970	COG4978	Transcriptional regulator
HYU01_04985	COG0305	Participates in initiation and elongation during chromosome replication
HYU01_05030	COG0477	Major facilitator Superfamily
HYU01_05105	COG1183	phosphatidylcholine synthase activity
HYU01_05125	COG2376	Dihydroxyacetone kinase
HYU01_05135	COG2376	Dihydroxyacetone kinase
HYU01_05140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HYU01_05145	COG1959	2 iron, 2 sulfur cluster binding
HYU01_05170	COG3437	response regulator, receiver
HYU01_05170	COG2770	Histidine kinase
HYU01_05225	COG3237	CsbD-like
HYU01_05250	COG1191	sigma factor activity
HYU01_05260	COG2208	phosphoserine phosphatase activity
HYU01_05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HYU01_05270	COG0784	Response regulator, receiver
HYU01_05270	COG2205	protein histidine kinase activity
HYU01_05270	COG2198	Histidine kinase
HYU01_05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HYU01_05295	COG0393	Putative heavy-metal-binding
HYU01_05335	COG0420	3'-5' exonuclease activity
HYU01_05340	COG4717	serine-type aminopeptidase activity
HYU01_05365	COG1309	transcriptional regulator
HYU01_05370	COG2814	Major facilitator Superfamily
HYU01_05375	COG0346	lactoylglutathione lyase activity
HYU01_05380	COG0346	lactoylglutathione lyase activity
HYU01_05385	COG0457	Tetratricopeptide repeat
HYU01_05395	COG2267	carboxylic ester hydrolase activity
HYU01_05415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HYU01_05420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HYU01_05430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HYU01_05470	COG0477	Major facilitator Superfamily
HYU01_05475	COG0477	Major facilitator Superfamily
HYU01_05485	COG3973	AAA domain
HYU01_05490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HYU01_05515	COG4980	gas vesicle protein
HYU01_05520	COG0537	adenosine 5'-monophosphoramidase activity
HYU01_05525	COG1131	(ABC) transporter
HYU01_05530	COG4473	ABC transporter
HYU01_05545	COG1309	transcriptional regulator
HYU01_05555	COG3402	PFAM membrane-flanked domain
HYU01_05565	COG3428	Bacterial PH domain
HYU01_05605	COG3402	PFAM membrane-flanked domain
HYU01_05610	COG3428	Bacterial PH domain
HYU01_05615	COG2329	Antibiotic biosynthesis monooxygenase
HYU01_05620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HYU01_05625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HYU01_05670	COG1309	transcriptional regulator
HYU01_05675	COG1511	domain protein
HYU01_05700	COG1609	Transcriptional regulator
HYU01_05710	COG1234	tRNA 3'-trailer cleavage
HYU01_05715	COG0095	Lipoate-protein ligase
HYU01_05725	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_05755	COG3209	COG3209 Rhs family protein
HYU01_05785	COG1408	metallophosphoesterase
HYU01_05790	COG1078	dGTPase activity
HYU01_05800	COG1595	DNA-templated transcription, initiation
HYU01_05805	COG3708	Transcriptional regulator
HYU01_05805	COG2207	Transcriptional regulator
HYU01_05820	COG2205	protein histidine kinase activity
HYU01_05825	COG0745	RESPONSE REGULATOR receiver
HYU01_05850	COG0501	Belongs to the peptidase M48B family
HYU01_05855	COG0840	transmembrane signaling receptor activity
HYU01_05860	COG0697	spore germination
HYU01_05875	COG0497	DNA recombination
HYU01_05880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HYU01_05885	COG2224	Isocitrate lyase
HYU01_05895	COG1278	Cold shock
HYU01_05910	COG4903	ComK protein
HYU01_05915	COG0398	Pfam SNARE associated Golgi protein
HYU01_05925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HYU01_05930	COG1074	ATP-dependent DNA helicase activity
HYU01_05975	COG0179	Fumarylacetoacetate (FAA) hydrolase
HYU01_06000	COG0367	asparagine synthase
HYU01_06010	COG0753	catalase activity
HYU01_06015	COG0004	ammonium transporteR
HYU01_06035	COG2996	Protein conserved in bacteria
HYU01_06045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HYU01_06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_06070	COG0561	phosphatase activity
HYU01_06080	COG0542	response to heat
HYU01_06090	COG2267	carboxylic ester hydrolase activity
HYU01_06105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HYU01_06115	COG5504	Zn-dependent protease
HYU01_06125	COG0180	Tryptophanyl-tRNA synthetase
HYU01_06135	COG4166	transmembrane transport
HYU01_06140	COG0601	transmembrane transport
HYU01_06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HYU01_06150	COG0444	Belongs to the ABC transporter superfamily
HYU01_06155	COG4608	Belongs to the ABC transporter superfamily
HYU01_06160	COG0534	Mate efflux family protein
HYU01_06165	COG4166	transmembrane transport
HYU01_06175	COG1393	Belongs to the ArsC family
HYU01_06180	COG0861	Integral membrane protein TerC family
HYU01_06185	COG4862	establishment of competence for transformation
HYU01_06190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HYU01_06200	COG1164	Oligoendopeptidase f
HYU01_06215	COG2346	COG2346, Truncated hemoglobins
HYU01_06220	COG4116	CYTH
HYU01_06230	COG2357	RelA SpoT domain protein
HYU01_06235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HYU01_06240	COG0564	pseudouridine synthase activity
HYU01_06255	COG0772	Belongs to the SEDS family
HYU01_06260	COG1216	Glycosyl transferase, family 2
HYU01_06280	COG0457	Tetratricopeptide repeat
HYU01_06280	COG0463	Glycosyl transferase, family 2
HYU01_06300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HYU01_06315	COG1091	dTDP-4-dehydrorhamnose reductase activity
HYU01_06360	COG2153	protein acetylation
HYU01_06365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HYU01_06370	COG2382	esterase
HYU01_06385	COG5492	domain, Protein
HYU01_06390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HYU01_06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HYU01_06405	COG0512	Glutamine amidotransferase of anthranilate synthase
HYU01_06440	COG1620	l-lactate permease
HYU01_06445	COG5634	Uncharacterized conserved protein (DUF2278)
HYU01_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
HYU01_06505	COG1476	TRANSCRIPTIONal
HYU01_06560	COG2226	methyltransferase
HYU01_06570	COG1686	Belongs to the peptidase S11 family
HYU01_06575	COG0681	Belongs to the peptidase S26 family
HYU01_06610	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_06615	COG3842	ATPase activity
HYU01_06620	COG1176	ABC-type spermidine putrescine transport system, permease component I
HYU01_06625	COG1177	transmembrane transport
HYU01_06630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HYU01_06640	COG2409	Drug exporters of the RND superfamily
HYU01_06650	COG0564	pseudouridine synthase activity
HYU01_06660	COG2340	Cysteine-rich secretory protein family
HYU01_06665	COG0247	lactate metabolic process
HYU01_06670	COG0277	FAD linked oxidase domain protein
HYU01_06675	COG3835	regulator
HYU01_06685	COG0745	RESPONSE REGULATOR receiver
HYU01_06690	COG5002	protein histidine kinase activity
HYU01_06695	COG2186	Transcriptional regulator
HYU01_06715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HYU01_06725	COG2116	formate transmembrane transporter activity
HYU01_06730	COG0861	Integral membrane protein TerC family
HYU01_06745	COG2030	dehydratase
HYU01_06765	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_06770	COG3243	poly(R)-hydroxyalkanoic acid synthase
HYU01_06780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HYU01_06795	COG1840	ABC-type Fe3 transport system, periplasmic component
HYU01_06820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HYU01_06835	COG1349	DNA-binding transcription factor activity
HYU01_06860	COG2861	carbohydrate metabolic process
HYU01_06870	COG3852	Histidine kinase
HYU01_06875	COG1846	Transcriptional regulator
HYU01_06885	COG2318	DinB family
HYU01_06895	COG5002	protein histidine kinase activity
HYU01_06905	COG0720	synthase
HYU01_06920	COG4873	Protein conserved in bacteria
HYU01_06950	COG1780	Probably involved in ribonucleotide reductase function
HYU01_06970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HYU01_06975	COG1725	Transcriptional regulator
HYU01_06980	COG1131	(ABC) transporter
HYU01_06990	COG1131	(ABC) transporter
HYU01_06995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HYU01_07010	COG1522	sequence-specific DNA binding
HYU01_07020	COG1335	isochorismatase
HYU01_07030	COG1619	proteins homologs of microcin C7 resistance protein MccF
HYU01_07035	COG2070	2-Nitropropane dioxygenase
HYU01_07040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HYU01_07050	COG1696	Membrane protein involved in D-alanine export
HYU01_07075	COG0716	FMN binding
HYU01_07090	COG3173	Aminoglycoside phosphotransferase
HYU01_07110	COG0534	Mate efflux family protein
HYU01_07115	COG1968	undecaprenyl-diphosphatase activity
HYU01_07130	COG1846	Transcriptional regulator
HYU01_07140	COG1301	dicarboxylic acid transport
HYU01_07145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HYU01_07150	COG4709	membrane
HYU01_07155	COG3874	Sporulation protein YtfJ
HYU01_07180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HYU01_07185	COG0028	Belongs to the TPP enzyme family
HYU01_07190	COG0440	acetolactate synthase activity
HYU01_07195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HYU01_07205	COG0473	3-isopropylmalate dehydrogenase activity
HYU01_07230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HYU01_07265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HYU01_07280	COG1183	phosphatidylcholine synthase activity
HYU01_07285	COG1368	sulfuric ester hydrolase activity
HYU01_07295	COG0019	diaminopimelate decarboxylase activity
HYU01_07315	COG0529	Catalyzes the synthesis of activated sulfate
HYU01_07320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HYU01_07340	COG1648	precorrin-2 dehydrogenase activity
HYU01_07345	COG0733	neurotransmitter:sodium symporter activity
HYU01_07365	COG1757	Na H antiporter
HYU01_07380	COG4758	membrane
HYU01_07385	COG4585	Histidine kinase
HYU01_07390	COG2197	response regulator
HYU01_07400	COG1114	Component of the transport system for branched-chain amino acids
HYU01_07410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HYU01_07440	COG1017	nitric oxide dioxygenase activity
HYU01_07440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HYU01_07455	COG0730	response to heat
HYU01_07460	COG0306	phosphate transporter
HYU01_07465	COG1392	Phosphate transport regulator
HYU01_07490	COG3852	Histidine kinase
HYU01_07495	COG1801	Protein of unknown function DUF72
HYU01_07510	COG0582	viral genome integration into host DNA
HYU01_07515	COG5002	protein histidine kinase activity
HYU01_07535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HYU01_07535	COG0392	lysyltransferase activity
HYU01_07550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HYU01_07555	COG1686	Belongs to the peptidase S11 family
HYU01_07560	COG2715	membrane protein required for spore maturation
HYU01_07565	COG0700	Nucleoside recognition
HYU01_07570	COG1187	pseudouridine synthase activity
HYU01_07580	COG1333	cytochrome c biogenesis protein
HYU01_07585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HYU01_07590	COG0745	RESPONSE REGULATOR receiver
HYU01_07595	COG5002	protein histidine kinase activity
HYU01_07600	COG2096	Adenosyltransferase
HYU01_07615	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HYU01_07620	COG1141	Ferredoxin
HYU01_07625	COG4955	Helix-turn-helix domain
HYU01_07630	COG0514	ATP-dependent DNA helicase (RecQ)
HYU01_07635	COG1266	CAAX protease self-immunity
HYU01_07655	COG4862	establishment of competence for transformation
HYU01_07660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HYU01_07680	COG0492	ferredoxin-NADP+ reductase activity
HYU01_07685	COG0252	asparaginase activity
HYU01_07755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HYU01_07770	COG0142	geranyltranstransferase activity
HYU01_07780	COG0142	geranyltranstransferase activity
HYU01_07785	COG0105	UTP biosynthetic process
HYU01_07800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HYU01_07805	COG0457	Tetratricopeptide repeat
HYU01_07825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HYU01_07835	COG4347	Protein of unknown function (DUF1405)
HYU01_07850	COG2738	Putative neutral zinc metallopeptidase
HYU01_07860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_07865	COG1694	Mazg nucleotide pyrophosphohydrolase
HYU01_07880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HYU01_07885	COG0438	transferase activity, transferring glycosyl groups
HYU01_07940	COG3935	DnaD domain protein
HYU01_07945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HYU01_07955	COG4499	WXG100 protein secretion system (Wss), protein YukC
HYU01_07955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HYU01_08000	COG4474	Belongs to the UPF0398 family
HYU01_08010	COG0116	Belongs to the methyltransferase superfamily
HYU01_08020	COG1199	ATP-dependent helicase activity
HYU01_08025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HYU01_08035	COG3173	Aminoglycoside phosphotransferase
HYU01_08040	COG0024	Methionine aminopeptidase
HYU01_08050	COG2233	PERMEase
HYU01_08055	COG2311	Membrane
HYU01_08065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HYU01_08075	COG0456	acetyltransferase
HYU01_08100	COG0754	glutathionylspermidine amidase activity
HYU01_08120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HYU01_08145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HYU01_08160	COG1215	transferase activity, transferring glycosyl groups
HYU01_08180	COG0454	-acetyltransferase
HYU01_08205	COG0328	RNA-DNA hybrid ribonuclease activity
HYU01_08245	COG1280	lysine exporter protein (LysE YggA)
HYU01_08260	COG3162	membrane
HYU01_08265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HYU01_08270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HYU01_08280	COG0475	glutathione-regulated potassium exporter activity
HYU01_08285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HYU01_08290	COG0789	Transcriptional regulator
HYU01_08290	COG4978	Transcriptional regulator
HYU01_08300	COG2323	membrane
HYU01_08305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HYU01_08360	COG1923	regulation of RNA biosynthetic process
HYU01_08370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HYU01_08375	COG1360	Flagellar Motor Protein
HYU01_08380	COG2201	protein-glutamate methylesterase activity
HYU01_08390	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HYU01_08390	COG1776	CheC inhibitor of MCP methylation
HYU01_08405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HYU01_08425	COG1256	bacterial-type flagellum assembly
HYU01_08430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HYU01_08455	COG1815	bacterial-type flagellum-dependent cell motility
HYU01_08460	COG1558	bacterial-type flagellum-dependent cell motility
HYU01_08465	COG1677	Flagellar hook-basal body complex protein FliE
HYU01_08470	COG1766	The M ring may be actively involved in energy transduction
HYU01_08480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HYU01_08490	COG1157	protein secretion by the type III secretion system
HYU01_08535	COG0835	chemotaxis
HYU01_08535	COG0784	Response regulator, receiver
HYU01_08545	COG0463	Glycosyl transferase, family 2
HYU01_08580	COG0457	Tetratricopeptide repeat
HYU01_08580	COG0463	Glycosyl transferase, family 2
HYU01_08605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HYU01_08610	COG0741	lytic transglycosylase activity
HYU01_08625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HYU01_08625	COG1776	CheC inhibitor of MCP methylation
HYU01_08635	COG1338	Plays a role in the flagellum-specific transport system
HYU01_08640	COG1987	bacterial-type flagellum assembly
HYU01_08650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HYU01_08655	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HYU01_08660	COG1419	protein localization to endoplasmic reticulum
HYU01_08665	COG4786	Flagellar basal body rod
HYU01_08670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HYU01_08695	COG1309	transcriptional regulator
HYU01_08715	COG2329	Antibiotic biosynthesis monooxygenase
HYU01_08745	COG3842	ATPase activity
HYU01_08750	COG0725	ABC transporter, periplasmic molybdate-binding protein
HYU01_08755	COG1177	transmembrane transport
HYU01_08760	COG1234	tRNA 3'-trailer cleavage
HYU01_08785	COG1686	Belongs to the peptidase S11 family
HYU01_08795	COG0406	alpha-ribazole phosphatase activity
HYU01_08825	COG0367	asparagine synthase
HYU01_08855	COG1802	Transcriptional regulator
HYU01_08860	COG0697	spore germination
HYU01_08865	COG0523	cobalamin synthesis protein
HYU01_08870	COG0701	Predicted permease
HYU01_08880	COG0438	transferase activity, transferring glycosyl groups
HYU01_08880	COG1216	Glycosyl transferase, family 2
HYU01_08885	COG1757	Na H antiporter
HYU01_08890	COG0114	fumarate hydratase activity
HYU01_08915	COG3340	Belongs to the peptidase S51 family
HYU01_08935	COG0785	Cytochrome C biogenesis protein
HYU01_08970	COG2733	membrane
HYU01_09005	COG1131	(ABC) transporter
HYU01_09020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HYU01_09025	COG0528	UMP kinase activity
HYU01_09035	COG1027	Aspartate ammonia-lyase
HYU01_09040	COG0281	malic enzyme
HYU01_09045	COG4191	Histidine kinase
HYU01_09050	COG0784	Response regulator, receiver
HYU01_09060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HYU01_09125	COG0860	N-Acetylmuramoyl-L-alanine amidase
HYU01_09150	COG1966	Carbon starvation protein
HYU01_09160	COG0477	Major facilitator Superfamily
HYU01_09165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HYU01_09185	COG4166	transmembrane transport
HYU01_09210	COG2244	polysaccharide biosynthetic process
HYU01_09215	COG0733	neurotransmitter:sodium symporter activity
HYU01_09230	COG5566	PFAM Mor transcription activator
HYU01_09235	COG2323	membrane
HYU01_09255	COG2084	Dehydrogenase
HYU01_09275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HYU01_09285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HYU01_09290	COG0028	Belongs to the TPP enzyme family
HYU01_09295	COG0440	acetolactate synthase activity
HYU01_09300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HYU01_09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HYU01_09340	COG3384	dioxygenase
HYU01_09350	COG3279	Response regulator of the LytR AlgR family
HYU01_09355	COG0427	acetyl-CoA hydrolase
HYU01_09375	COG1073	alpha beta
HYU01_09385	COG4166	transmembrane transport
HYU01_09425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_09445	COG1914	H( )-stimulated, divalent metal cation uptake system
HYU01_09460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HYU01_09495	COG2390	Transcriptional regulator
HYU01_09505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_09510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HYU01_09520	COG4224	UPF0291 protein
HYU01_09540	COG0006	proline dipeptidase activity
HYU01_09545	COG2132	Multicopper oxidase
HYU01_09575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HYU01_09590	COG2372	response to copper ion
HYU01_09590	COG1276	copper resistance
HYU01_09595	COG4549	nuclear export factor GLE1
HYU01_09605	COG0697	spore germination
HYU01_09610	COG0583	DNA-binding transcription factor activity
HYU01_09615	COG1959	2 iron, 2 sulfur cluster binding
HYU01_09620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HYU01_09625	COG0778	Nitroreductase
HYU01_09640	COG0628	permease
HYU01_09645	COG0039	L-malate dehydrogenase activity
HYU01_09650	COG1231	oxidoreductase activity
HYU01_09655	COG0523	cobalamin synthesis protein
HYU01_09670	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_09675	COG2030	dehydratase
HYU01_09680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_09690	COG0411	ABC transporter
HYU01_09710	COG0583	DNA-binding transcription factor activity
HYU01_09730	COG1846	Transcriptional regulator
HYU01_09740	COG1271	oxidase subunit
HYU01_09745	COG1294	oxidase, subunit
HYU01_09750	COG4988	ABC transporter
HYU01_09755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HYU01_09775	COG1686	Belongs to the peptidase S11 family
HYU01_09785	COG0791	NLP P60 protein
HYU01_09785	COG1388	LysM domain
HYU01_09795	COG1132	(ABC) transporter
HYU01_09800	COG1132	(ABC) transporter
HYU01_09805	COG0745	RESPONSE REGULATOR receiver
HYU01_09820	COG0300	oxidoreductase activity
HYU01_09835	COG0726	polysaccharide deacetylase
HYU01_09860	COG0460	homoserine dehydrogenase
HYU01_09885	COG1316	TRANSCRIPTIONal
HYU01_09895	COG0745	RESPONSE REGULATOR receiver
HYU01_09900	COG5002	protein histidine kinase activity
HYU01_09905	COG0726	polysaccharide deacetylase
HYU01_09915	COG1285	pathogenesis
HYU01_09920	COG1247	-acetyltransferase
HYU01_09930	COG4264	IucA IucC family
HYU01_09935	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_09950	COG1082	Xylose isomerase domain protein TIM barrel
HYU01_09960	COG2814	Major facilitator Superfamily
HYU01_09965	COG1279	arginine transmembrane transporter activity
HYU01_09975	COG1752	Esterase of the alpha-beta hydrolase superfamily
HYU01_10010	COG0577	efflux transmembrane transporter activity
HYU01_10015	COG2002	toxin-antitoxin pair type II binding
HYU01_10020	COG1404	Belongs to the peptidase S8 family
HYU01_10025	COG0640	Transcriptional regulator
HYU01_10030	COG0667	Aldo Keto reductase
HYU01_10060	COG0840	transmembrane signaling receptor activity
HYU01_10075	COG3949	Membrane
HYU01_10080	COG0783	Belongs to the Dps family
HYU01_10095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HYU01_10105	COG1231	oxidoreductase activity
HYU01_10115	COG4989	oxidoreductase activity
HYU01_10120	COG0523	cobalamin synthesis protein
HYU01_10125	COG0456	acetyltransferase
HYU01_10185	COG3443	Belongs to the bacterial solute-binding protein 9 family
HYU01_10185	COG0803	Belongs to the bacterial solute-binding protein 9 family
HYU01_10195	COG0702	epimerase
HYU01_10205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HYU01_10215	COG4166	transmembrane transport
HYU01_10230	COG0406	alpha-ribazole phosphatase activity
HYU01_10240	COG5337	Spore coat protein CotH
HYU01_10245	COG1051	belongs to the nudix hydrolase family
HYU01_10250	COG0586	Pfam SNARE associated Golgi protein
HYU01_10255	COG2244	polysaccharide biosynthetic process
HYU01_10265	COG0701	Predicted permease
HYU01_10270	COG3689	TIGRFAM TIGR03943 family protein
HYU01_10275	COG1607	acyl-coa hydrolase
HYU01_10285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HYU01_10300	COG0702	epimerase
HYU01_10305	COG2839	Protein conserved in bacteria
HYU01_10310	COG1253	flavin adenine dinucleotide binding
HYU01_10325	COG1114	Component of the transport system for branched-chain amino acids
HYU01_10330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_10345	COG0860	N-Acetylmuramoyl-L-alanine amidase
HYU01_10355	COG1876	peptidase activity
HYU01_10365	COG0154	amidase activity
HYU01_10370	COG2211	Major facilitator Superfamily
HYU01_10390	COG0561	phosphatase activity
HYU01_10400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HYU01_10420	COG1819	glycosyl
HYU01_10425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_10430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_10460	COG0456	acetyltransferase
HYU01_10510	COG3874	Sporulation protein YtfJ
HYU01_10555	COG1082	Xylose isomerase domain protein TIM barrel
HYU01_10560	COG0346	lactoylglutathione lyase activity
HYU01_10570	COG0604	alcohol dehydrogenase
HYU01_10575	COG1595	DNA-templated transcription, initiation
HYU01_10600	COG0386	Belongs to the glutathione peroxidase family
HYU01_10605	COG1305	Transglutaminase-like
HYU01_10610	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HYU01_10615	COG0714	Associated with various cellular activities
HYU01_10630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HYU01_10635	COG1140	nitrate reductase beta subunit
HYU01_10640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HYU01_10645	COG2181	nitrate reductase activity
HYU01_10665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HYU01_10670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HYU01_10675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HYU01_10680	COG0303	'Molybdopterin
HYU01_10685	COG0314	molybdopterin synthase activity
HYU01_10695	COG2223	nitrite transmembrane transporter activity
HYU01_10710	COG1648	precorrin-2 dehydrogenase activity
HYU01_10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HYU01_10720	COG1587	Uroporphyrinogen-III synthase
HYU01_10725	COG2146	nitrite reductase [NAD(P)H] activity
HYU01_10735	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HYU01_10770	COG2359	stage V sporulation protein S
HYU01_10790	COG5632	N-Acetylmuramoyl-L-alanine amidase
HYU01_10805	COG1418	mRNA catabolic process
HYU01_10810	COG0488	(ABC) transporter
HYU01_10825	COG0629	single-stranded DNA binding
HYU01_10840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HYU01_10845	COG1413	lyase activity
HYU01_10860	COG2521	methyltransferase
HYU01_10860	COG2136	Putative SAM-dependent methyltransferase
HYU01_10865	COG0018	arginyl-trna synthetase
HYU01_10890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HYU01_10905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HYU01_10910	COG0017	Asparaginyl-tRNA synthetase
HYU01_10930	COG1674	ftsk spoiiie
HYU01_11020	COG1929	Belongs to the glycerate kinase type-1 family
HYU01_11025	COG0471	metal ion transport
HYU01_11030	COG0745	RESPONSE REGULATOR receiver
HYU01_11035	COG3850	Histidine kinase
HYU01_11035	COG5002	protein histidine kinase activity
HYU01_11050	COG0733	neurotransmitter:sodium symporter activity
HYU01_11075	COG2610	gluconate transmembrane transporter activity
HYU01_11080	COG1454	alcohol dehydrogenase
HYU01_11085	COG1794	racemase activity, acting on amino acids and derivatives
HYU01_11095	COG0456	acetyltransferase
HYU01_11110	COG1131	(ABC) transporter
HYU01_11115	COG4473	ABC transporter
HYU01_11130	COG0546	phosphoglycolate phosphatase activity
HYU01_11150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HYU01_11165	COG0768	penicillin binding
HYU01_11170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HYU01_11175	COG0204	Acyl-transferase
HYU01_11180	COG1272	protein, Hemolysin III
HYU01_11190	COG0805	protein transport
HYU01_11200	COG1307	EDD domain protein, DegV family
HYU01_11205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HYU01_11210	COG1999	signal sequence binding
HYU01_11215	COG0071	Belongs to the small heat shock protein (HSP20) family
HYU01_11220	COG0367	asparagine synthase
HYU01_11240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_11245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HYU01_11280	COG0668	transmembrane transport
HYU01_11285	COG2203	Gaf domain
HYU01_11285	COG4585	Histidine kinase
HYU01_11290	COG2197	response regulator
HYU01_11300	COG1737	Transcriptional regulator
HYU01_11305	COG1064	alcohol dehydrogenase
HYU01_11335	COG1070	Carbohydrate kinase
HYU01_11370	COG0517	IMP dehydrogenase activity
HYU01_11370	COG1125	glycine betaine transport
HYU01_11375	COG1174	glycine betaine transport
HYU01_11410	COG1253	flavin adenine dinucleotide binding
HYU01_11415	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_11420	COG5506	Protein of unknown function (DUF1694)
HYU01_11435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HYU01_11440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HYU01_11445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HYU01_11450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HYU01_11455	COG0456	acetyltransferase
HYU01_11460	COG3829	transcription factor binding
HYU01_11465	COG1509	lysine 2,3-aminomutase activity
HYU01_11505	COG4326	sporulation control protein
HYU01_11510	COG0671	phosphoesterase, PA-phosphatase related
HYU01_11515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HYU01_11520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HYU01_11550	COG1787	Restriction endonuclease
HYU01_11550	COG1715	Restriction endonuclease
HYU01_11640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HYU01_11675	COG4499	WXG100 protein secretion system (Wss), protein YukC
HYU01_11675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HYU01_11685	COG2814	Major facilitator Superfamily
HYU01_11690	COG4841	protein insertion into membrane
HYU01_11695	COG0372	Belongs to the citrate synthase family
HYU01_11700	COG2079	MmgE PrpD family protein
HYU01_11705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HYU01_11710	COG1960	acyl-CoA dehydrogenase activity
HYU01_11715	COG2084	Dehydrogenase
HYU01_11720	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_11725	COG1280	lysine exporter protein (LysE YggA)
HYU01_11730	COG1024	Enoyl-CoA hydratase
HYU01_11745	COG0420	3'-5' exonuclease activity
HYU01_11750	COG0419	ATPase involved in DNA repair
HYU01_11780	COG2223	nitrite transmembrane transporter activity
HYU01_11785	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_11790	COG1169	isochorismate synthase
HYU01_11795	COG1021	2,3-dihydroxybenzoate-AMP ligase
HYU01_11800	COG1535	isochorismatase
HYU01_11800	COG3433	isochorismatase activity
HYU01_11810	COG3251	PFAM MbtH domain protein
HYU01_11815	COG2814	Major facilitator Superfamily
HYU01_11830	COG0776	regulation of translation
HYU01_11840	COG2318	DinB family
HYU01_11870	COG2329	Antibiotic biosynthesis monooxygenase
HYU01_11875	COG1187	pseudouridine synthase activity
HYU01_11880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HYU01_11895	COG0596	Alpha beta hydrolase
HYU01_11900	COG2814	Major facilitator Superfamily
HYU01_11920	COG2226	methyltransferase
HYU01_11965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_12000	COG1247	-acetyltransferase
HYU01_12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_12050	COG1278	Cold shock
HYU01_12065	COG0010	Belongs to the arginase family
HYU01_12070	COG0561	phosphatase activity
HYU01_12115	COG0583	DNA-binding transcription factor activity
HYU01_12120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HYU01_12135	COG0583	DNA-binding transcription factor activity
HYU01_12140	COG2258	MOSC domain
HYU01_12155	COG1132	(ABC) transporter
HYU01_12160	COG1132	(ABC) transporter
HYU01_12180	COG1396	sequence-specific DNA binding
HYU01_12210	COG1595	DNA-templated transcription, initiation
HYU01_12235	COG1649	PFAM Uncharacterised BCR, COG1649
HYU01_12260	COG2971	BadF BadG BcrA BcrD
HYU01_12265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HYU01_12270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HYU01_12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_12320	COG1309	transcriptional regulator
HYU01_12335	COG1136	(ABC) transporter
HYU01_12335	COG0577	efflux transmembrane transporter activity
HYU01_12340	COG3615	Tellurite resistance protein tehB
HYU01_12340	COG0500	methyltransferase
HYU01_12350	COG2226	methyltransferase
HYU01_12355	COG3961	Belongs to the TPP enzyme family
HYU01_12360	COG1846	Transcriptional regulator
HYU01_12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
HYU01_12425	COG1595	DNA-templated transcription, initiation
HYU01_12435	COG0768	penicillin binding
HYU01_12445	COG2367	Beta-lactamase
HYU01_12450	COG0671	phosphoesterase, PA-phosphatase related
HYU01_12455	COG1609	Transcriptional regulator
HYU01_12465	COG0673	inositol 2-dehydrogenase activity
HYU01_12475	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_12510	COG0737	Belongs to the 5'-nucleotidase family
HYU01_12520	COG0457	Tetratricopeptide repeat
HYU01_12525	COG1476	TRANSCRIPTIONal
HYU01_12540	COG1876	peptidase activity
HYU01_12565	COG1309	transcriptional regulator
HYU01_12585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_12600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_12615	COG1131	(ABC) transporter
HYU01_12625	COG1309	transcriptional regulator
HYU01_12640	COG1960	acyl-CoA dehydrogenase activity
HYU01_12645	COG0439	Biotin carboxylase
HYU01_12650	COG0511	ligase activity, forming carbon-carbon bonds
HYU01_12655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HYU01_12660	COG1024	Enoyl-CoA hydratase
HYU01_12665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HYU01_12670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HYU01_12680	COG1247	-acetyltransferase
HYU01_12685	COG0572	uridine kinase
HYU01_12695	COG2318	DinB family
HYU01_12700	COG1686	Belongs to the peptidase S11 family
HYU01_12725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HYU01_12780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HYU01_12790	COG2814	Major facilitator Superfamily
HYU01_12810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HYU01_12830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_12840	COG1063	alcohol dehydrogenase
HYU01_12855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HYU01_12860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HYU01_12875	COG3773	Cell wall hydrolase
HYU01_12885	COG0745	RESPONSE REGULATOR receiver
HYU01_12915	COG1136	(ABC) transporter
HYU01_12940	COG0460	homoserine dehydrogenase
HYU01_12945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_12955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HYU01_13045	COG2124	cytochrome p450
HYU01_13085	COG0561	phosphatase activity
HYU01_13095	COG5002	protein histidine kinase activity
HYU01_13105	COG1819	glycosyl
HYU01_13110	COG1794	racemase activity, acting on amino acids and derivatives
HYU01_13120	COG1122	ATPase activity
HYU01_13135	COG2205	protein histidine kinase activity
HYU01_13150	COG0604	alcohol dehydrogenase
HYU01_13165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HYU01_13200	COG0693	protein deglycase activity
HYU01_13230	COG2814	Major facilitator Superfamily
HYU01_13250	COG0584	glycerophosphoryl diester phosphodiesterase
HYU01_13270	COG0697	spore germination
HYU01_13305	COG2223	nitrite transmembrane transporter activity
HYU01_13315	COG2816	NAD+ diphosphatase activity
HYU01_13320	COG0592	DNA-directed DNA polymerase activity
HYU01_13325	COG1051	belongs to the nudix hydrolase family
HYU01_13360	COG3878	Protein conserved in bacteria
HYU01_13415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HYU01_13430	COG0322	excinuclease ABC activity
HYU01_13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HYU01_13500	COG1011	Hydrolase
HYU01_13520	COG0076	glutamate decarboxylase activity
HYU01_13535	COG1523	belongs to the glycosyl hydrolase 13 family
HYU01_13540	COG3227	Zinc metalloprotease (Elastase)
HYU01_13560	COG0201	protein transport
HYU01_13570	COG0697	spore germination
HYU01_13575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_13605	COG4129	membrane
HYU01_13610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_13625	COG2959	enzyme of heme biosynthesis
HYU01_13630	COG3409	Peptidoglycan-binding domain 1 protein
HYU01_13630	COG3773	Cell wall hydrolase
HYU01_13645	COG3483	tryptophan 2,3-dioxygenase activity
HYU01_13650	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HYU01_13655	COG3844	kynureninase activity
HYU01_13660	COG1309	transcriptional regulator
HYU01_13690	COG3284	Transcriptional regulator
HYU01_13710	COG1349	DNA-binding transcription factor activity
HYU01_13730	COG1959	2 iron, 2 sulfur cluster binding
HYU01_13750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HYU01_13755	COG0508	dehydrogenase complex catalyzes the overall conversion of
HYU01_13760	COG0022	dehydrogenase e1 component
HYU01_13765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HYU01_13780	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_13785	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HYU01_13785	COG0456	acetyltransferase
HYU01_13810	COG4176	ABC-type proline glycine betaine transport system permease component
HYU01_13815	COG0517	IMP dehydrogenase activity
HYU01_13815	COG4175	Glycine betaine
HYU01_13825	COG0740	serine-type endopeptidase activity
HYU01_13840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HYU01_13845	COG2153	protein acetylation
HYU01_13850	COG3397	chitin binding
HYU01_13865	COG2205	protein histidine kinase activity
HYU01_13895	COG2333	competence protein COMEC
HYU01_13895	COG0658	competence protein
HYU01_13945	COG3973	AAA domain
HYU01_13960	COG2105	PFAM AIG2 family protein
HYU01_13965	COG0514	ATP-dependent DNA helicase (RecQ)
HYU01_13990	COG4637	Psort location Cytoplasmic, score
HYU01_14015	COG3397	chitin binding
HYU01_14025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HYU01_14030	COG1115	amino acid carrier protein
HYU01_14035	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_14040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HYU01_14050	COG3938	Belongs to the proline racemase family
HYU01_14055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HYU01_14095	COG0586	Pfam SNARE associated Golgi protein
HYU01_14110	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HYU01_14115	COG0519	Catalyzes the synthesis of GMP from XMP
HYU01_14120	COG4166	transmembrane transport
HYU01_14130	COG4948	Mandelate Racemase Muconate Lactonizing
HYU01_14175	COG2936	dipeptidyl-peptidase activity
HYU01_14185	COG5002	protein histidine kinase activity
HYU01_14190	COG0745	RESPONSE REGULATOR receiver
HYU01_14235	COG1307	EDD domain protein, DegV family
HYU01_14260	COG2814	Major facilitator Superfamily
HYU01_14270	COG1664	Polymer-forming cytoskeletal
HYU01_14275	COG0789	Transcriptional regulator
HYU01_14280	COG4533	DNA binding
HYU01_14285	COG2814	Major facilitator Superfamily
HYU01_14285	COG0477	Major facilitator Superfamily
HYU01_14305	COG2261	transglycosylase associated protein
HYU01_14320	COG2226	methyltransferase
HYU01_14355	COG0436	Aminotransferase
HYU01_14360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HYU01_14365	COG5146	pantothenate kinase activity
HYU01_14385	COG1131	(ABC) transporter
HYU01_14440	COG0628	permease
HYU01_14455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HYU01_14460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HYU01_14465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HYU01_14470	COG1116	anion transmembrane transporter activity
HYU01_14510	COG2746	aminoglycoside 3-N-acetyltransferase activity
HYU01_14535	COG0697	spore germination
HYU01_14540	COG2318	DinB family
HYU01_14560	COG4912	Dna alkylation repair
HYU01_14575	COG0726	polysaccharide deacetylase
HYU01_14585	COG0861	Integral membrane protein TerC family
HYU01_14590	COG1368	sulfuric ester hydrolase activity
HYU01_14595	COG0488	(ABC) transporter
HYU01_14605	COG2409	Drug exporters of the RND superfamily
HYU01_14605	COG1033	growth of symbiont in host cell
HYU01_14610	COG2409	Drug exporters of the RND superfamily
HYU01_14610	COG1033	growth of symbiont in host cell
HYU01_14615	COG1309	transcriptional regulator
HYU01_14630	COG0287	Prephenate dehydrogenase
HYU01_14635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HYU01_14640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HYU01_14645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HYU01_14645	COG1605	Chorismate mutase
HYU01_14680	COG3584	3D domain protein
HYU01_14680	COG1388	LysM domain
HYU01_14690	COG1595	DNA-templated transcription, initiation
HYU01_14715	COG1879	ABC-type sugar transport system periplasmic component
HYU01_14725	COG1172	Belongs to the binding-protein-dependent transport system permease family
HYU01_14735	COG2390	Transcriptional regulator
HYU01_14740	COG1070	Carbohydrate kinase
HYU01_14770	COG2329	Antibiotic biosynthesis monooxygenase
HYU01_14790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_14800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HYU01_14805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HYU01_14810	COG4187	Peptidase family M20/M25/M40
HYU01_14815	COG1414	Transcriptional regulator
HYU01_14820	COG0833	amino acid
HYU01_14825	COG1690	Belongs to the RtcB family
HYU01_14830	COG3239	Fatty acid desaturase
HYU01_14835	COG1785	Belongs to the alkaline phosphatase family
HYU01_14845	COG3655	Transcriptional regulator
HYU01_14860	COG4377	Putative membrane peptidase family (DUF2324)
HYU01_14870	COG3279	Response regulator of the LytR AlgR family
HYU01_14880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_14885	COG0346	lactoylglutathione lyase activity
HYU01_14905	COG0714	Associated with various cellular activities
HYU01_14930	COG0463	Glycosyl transferase, family 2
HYU01_14955	COG0463	Glycosyl transferase, family 2
HYU01_14965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HYU01_14970	COG0753	catalase activity
HYU01_14980	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HYU01_15005	COG0714	Associated with various cellular activities
HYU01_15015	COG0778	Nitroreductase
HYU01_15020	COG1846	Transcriptional regulator
HYU01_15055	COG1725	Transcriptional regulator
HYU01_15065	COG0577	efflux transmembrane transporter activity
HYU01_15065	COG1136	(ABC) transporter
HYU01_15090	COG2207	Transcriptional regulator
HYU01_15095	COG0456	acetyltransferase
HYU01_15115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_15135	COG0642	Histidine kinase
HYU01_15140	COG0745	RESPONSE REGULATOR receiver
HYU01_15145	COG0596	Alpha beta hydrolase
HYU01_15175	COG0730	response to heat
HYU01_15185	COG0833	amino acid
HYU01_15195	COG4335	DNA alkylation repair
HYU01_15245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HYU01_15280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HYU01_15285	COG1414	Transcriptional regulator
HYU01_15300	COG0860	N-Acetylmuramoyl-L-alanine amidase
HYU01_15305	COG0640	Transcriptional regulator
HYU01_15315	COG1960	acyl-CoA dehydrogenase activity
HYU01_15350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HYU01_15365	COG3848	Pyruvate phosphate dikinase
HYU01_15365	COG0574	Belongs to the PEP-utilizing enzyme family
HYU01_15370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_15385	COG5577	PFAM Coat F domain
HYU01_15395	COG3403	YqcI/YcgG family
HYU01_15400	COG1280	lysine exporter protein (LysE YggA)
HYU01_15435	COG1063	alcohol dehydrogenase
HYU01_15455	COG1027	Aspartate ammonia-lyase
HYU01_15460	COG0252	asparaginase activity
HYU01_15465	COG1396	sequence-specific DNA binding
HYU01_15475	COG0322	excinuclease ABC activity
HYU01_15480	COG0531	amino acid
HYU01_15485	COG1114	Component of the transport system for branched-chain amino acids
HYU01_15490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HYU01_15500	COG0281	malic enzyme
HYU01_15515	COG0531	amino acid
HYU01_15520	COG0697	spore germination
HYU01_15535	COG0784	Response regulator, receiver
HYU01_15545	COG2066	Belongs to the glutaminase family
HYU01_15555	COG1115	amino acid carrier protein
HYU01_15580	COG0737	Belongs to the 5'-nucleotidase family
HYU01_15585	COG0753	catalase activity
HYU01_15590	COG2267	carboxylic ester hydrolase activity
HYU01_15595	COG1335	isochorismatase
HYU01_15615	COG0583	DNA-binding transcription factor activity
HYU01_15625	COG0598	Magnesium transport protein CorA
HYU01_15660	COG0415	Belongs to the DNA photolyase family
HYU01_15665	COG0288	reversible hydration of carbon dioxide
HYU01_15675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HYU01_15680	COG5609	conserved protein (DUF2294)
HYU01_15690	COG1575	Belongs to the MenA family. Type 1 subfamily
HYU01_15695	COG2267	carboxylic ester hydrolase activity
HYU01_15700	COG0803	Belongs to the bacterial solute-binding protein 9 family
HYU01_15705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HYU01_15710	COG1121	(ABC) transporter
HYU01_15740	COG0798	PFAM Bile acid sodium symporter
HYU01_15745	COG0346	lactoylglutathione lyase activity
HYU01_15750	COG0640	Transcriptional regulator
HYU01_15770	COG0443	Heat shock 70 kDa protein
HYU01_15785	COG1522	sequence-specific DNA binding
HYU01_15800	COG0346	lactoylglutathione lyase activity
HYU01_15820	COG2169	Transcriptional regulator
HYU01_15865	COG2814	Major facilitator Superfamily
HYU01_15890	COG0745	RESPONSE REGULATOR receiver
HYU01_15895	COG5002	protein histidine kinase activity
HYU01_15895	COG3850	Histidine kinase
HYU01_15920	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HYU01_15950	COG1476	TRANSCRIPTIONal
HYU01_15965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_15970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HYU01_15980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_15985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HYU01_16000	COG1136	(ABC) transporter
HYU01_16005	COG0577	efflux transmembrane transporter activity
HYU01_16020	COG3850	Histidine kinase
HYU01_16020	COG5002	protein histidine kinase activity
HYU01_16030	COG2364	Membrane
HYU01_16035	COG1846	Transcriptional regulator
HYU01_16045	COG2808	Putative FMN-binding domain
HYU01_16050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_16055	COG2271	Major facilitator Superfamily
HYU01_16060	COG1556	Lactate utilization protein
HYU01_16065	COG1139	Iron-sulfur cluster binding protein
HYU01_16075	COG0583	DNA-binding transcription factor activity
HYU01_16085	COG1619	proteins homologs of microcin C7 resistance protein MccF
HYU01_16115	COG0673	inositol 2-dehydrogenase activity
HYU01_16120	COG0561	phosphatase activity
HYU01_16130	COG1609	Transcriptional regulator
HYU01_16135	COG0457	Tetratricopeptide repeat
HYU01_16160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HYU01_16195	COG0534	Mate efflux family protein
HYU01_16210	COG2814	Major facilitator Superfamily
HYU01_16215	COG1309	transcriptional regulator
HYU01_16225	COG0814	amino acid
HYU01_16230	COG1760	l-serine dehydratase
HYU01_16245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HYU01_16250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HYU01_16265	COG1522	sequence-specific DNA binding
HYU01_16270	COG0531	amino acid
HYU01_16285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HYU01_16305	COG1595	DNA-templated transcription, initiation
HYU01_16320	COG0662	Cupin 2, conserved barrel domain protein
HYU01_16330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_16330	COG2207	Transcriptional regulator
HYU01_16385	COG0477	Major facilitator Superfamily
HYU01_16395	COG1846	Transcriptional regulator
HYU01_16400	COG2814	Major facilitator Superfamily
HYU01_16415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HYU01_16420	COG1131	(ABC) transporter
HYU01_16440	COG2076	Multidrug Resistance protein
HYU01_16445	COG1309	transcriptional regulator
HYU01_16460	COG2031	fatty acid transporter
HYU01_16470	COG2249	NAD(P)H dehydrogenase (quinone) activity
HYU01_16500	COG1122	ATPase activity
HYU01_16505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HYU01_16520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HYU01_16525	COG1288	antiporter activity
HYU01_16530	COG2356	endonuclease I
HYU01_16545	COG3620	sequence-specific DNA binding
HYU01_16550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HYU01_16555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HYU01_16560	COG0124	histidyl-tRNA synthetase
HYU01_16575	COG1733	regulation of RNA biosynthetic process
HYU01_16580	COG0778	Nitroreductase
HYU01_16600	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_16610	COG1131	(ABC) transporter
HYU01_16635	COG1011	Hydrolase
HYU01_16670	COG0346	lactoylglutathione lyase activity
HYU01_16675	COG1940	carbohydrate kinase activity
HYU01_16680	COG0738	Major facilitator superfamily
HYU01_16685	COG0110	maltose O-acetyltransferase activity
HYU01_16695	COG1136	(ABC) transporter
HYU01_16705	COG0180	Tryptophanyl-tRNA synthetase
HYU01_16710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HYU01_16715	COG0628	permease
HYU01_16735	COG2226	methyltransferase
HYU01_16745	COG0477	Major facilitator Superfamily
HYU01_16775	COG1253	flavin adenine dinucleotide binding
HYU01_16780	COG0789	Transcriptional regulator
HYU01_16785	COG0697	spore germination
HYU01_16790	COG1357	PFAM Pentapeptide repeats (8 copies)
HYU01_16795	COG3813	Protein conserved in bacteria
HYU01_16800	COG2706	6-phosphogluconolactonase activity
HYU01_16805	COG1070	Carbohydrate kinase
HYU01_16815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HYU01_16820	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HYU01_16830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HYU01_16835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HYU01_16840	COG0604	alcohol dehydrogenase
HYU01_16845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HYU01_16860	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_16885	COG0656	L-ascorbic acid biosynthetic process
HYU01_16890	COG2814	Major facilitator Superfamily
HYU01_16905	COG0346	lactoylglutathione lyase activity
HYU01_16910	COG0814	amino acid
HYU01_16935	COG1393	Belongs to the ArsC family
HYU01_16940	COG1733	regulation of RNA biosynthetic process
HYU01_16945	COG2188	Transcriptional regulator
HYU01_16950	COG0673	inositol 2-dehydrogenase activity
HYU01_16955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HYU01_16960	COG1733	regulation of RNA biosynthetic process
HYU01_16965	COG1733	regulation of RNA biosynthetic process
HYU01_16980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_17000	COG0384	phenazine biosynthesis protein PhzF
HYU01_17010	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_17020	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_17030	COG1733	regulation of RNA biosynthetic process
HYU01_17065	COG1191	sigma factor activity
HYU01_17080	COG1309	transcriptional regulator
HYU01_17100	COG3152	Membrane
HYU01_17130	COG1151	hydroxylamine reductase activity
HYU01_17145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_17150	COG3409	Peptidoglycan-binding domain 1 protein
HYU01_17150	COG3757	hydrolase, family 25
HYU01_17185	COG2072	flavoprotein involved in K transport
HYU01_17225	COG0604	alcohol dehydrogenase
HYU01_17230	COG1113	amino acid transport
HYU01_17235	COG2814	Major facilitator Superfamily
HYU01_17265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HYU01_17270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HYU01_17290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_17300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_17310	COG3739	integral membrane protein
HYU01_17315	COG0384	phenazine biosynthesis protein PhzF
HYU01_17345	COG0583	DNA-binding transcription factor activity
HYU01_17365	COG1193	negative regulation of DNA recombination
HYU01_17380	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HYU01_17385	COG1164	Oligoendopeptidase f
HYU01_17390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HYU01_17420	COG0584	glycerophosphoryl diester phosphodiesterase
HYU01_17445	COG0640	Transcriptional regulator
HYU01_17450	COG0604	alcohol dehydrogenase
HYU01_17470	COG2808	Putative FMN-binding domain
HYU01_17485	COG0385	Bile acid
HYU01_17490	COG0277	FAD linked oxidase domain protein
HYU01_17525	COG1216	Glycosyl transferase, family 2
HYU01_17530	COG1024	Enoyl-CoA hydratase
HYU01_17540	COG1285	pathogenesis
HYU01_17550	COG2514	catechol 2,3-dioxygenase activity
HYU01_17555	COG2720	vancomycin resistance protein
HYU01_17585	COG1278	Cold shock
HYU01_17595	COG0716	FMN binding
HYU01_17625	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_17650	COG4145	pantothenate transmembrane transporter activity
HYU01_17655	COG3924	membrane
HYU01_17660	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_17665	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_17675	COG1657	PFAM Prenyltransferase squalene oxidase
HYU01_17680	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HYU01_17685	COG2962	Rard protein
HYU01_17690	COG3326	Membrane
HYU01_17705	COG0489	protein tyrosine kinase activity
HYU01_17715	COG0314	molybdopterin synthase activity
HYU01_17720	COG0303	'Molybdopterin
HYU01_17725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HYU01_17730	COG2116	formate transmembrane transporter activity
HYU01_17740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HYU01_17745	COG5609	conserved protein (DUF2294)
HYU01_17750	COG2427	Protein of unknown function (DUF1641)
HYU01_17755	COG3383	formate dehydrogenase (NAD+) activity
HYU01_17765	COG0697	spore germination
HYU01_17805	COG2226	methyltransferase
HYU01_17810	COG4166	transmembrane transport
HYU01_17815	COG4166	transmembrane transport
HYU01_17820	COG1301	dicarboxylic acid transport
HYU01_17825	COG1316	TRANSCRIPTIONal
HYU01_17835	COG1595	DNA-templated transcription, initiation
HYU01_17855	COG1131	(ABC) transporter
HYU01_17865	COG0673	inositol 2-dehydrogenase activity
HYU01_17870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HYU01_17875	COG0187	DNA topoisomerase II activity
HYU01_17880	COG1832	CoA-binding protein
HYU01_17885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HYU01_17890	COG0745	RESPONSE REGULATOR receiver
HYU01_17905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HYU01_17910	COG4841	protein insertion into membrane
HYU01_17915	COG0824	Thioesterase
HYU01_17945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HYU01_17955	COG2274	protein secretion by the type I secretion system
HYU01_17960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HYU01_17970	COG0726	polysaccharide deacetylase
HYU01_17985	COG2211	Major facilitator Superfamily
HYU01_17995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HYU01_18010	COG0183	Belongs to the thiolase family
HYU01_18015	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_18020	COG1268	BioY protein
HYU01_18025	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_18070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_18080	COG5002	protein histidine kinase activity
HYU01_18085	COG0400	carboxylic ester hydrolase activity
HYU01_18090	COG0346	lactoylglutathione lyase activity
HYU01_18095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HYU01_18100	COG0069	glutamate synthase activity
HYU01_18105	COG1902	pentaerythritol trinitrate reductase activity
HYU01_18110	COG1329	Transcriptional regulator
HYU01_18115	COG0010	Belongs to the arginase family
HYU01_18140	COG2226	methyltransferase
HYU01_18215	COG4846	Membrane protein involved in cytochrome C biogenesis
HYU01_18220	COG0785	Cytochrome C biogenesis protein
HYU01_18230	COG0583	DNA-binding transcription factor activity
HYU01_18235	COG1380	Effector of murein hydrolase LrgA
HYU01_18240	COG1346	cytolysis
HYU01_18260	COG0730	response to heat
HYU01_18270	COG5632	N-Acetylmuramoyl-L-alanine amidase
HYU01_18270	COG3409	Peptidoglycan-binding domain 1 protein
HYU01_18285	COG1132	(ABC) transporter
HYU01_18290	COG1132	(ABC) transporter
HYU01_18320	COG3639	organic phosphonate transmembrane transporter activity
HYU01_18325	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HYU01_18345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HYU01_18365	COG1695	Transcriptional regulator
HYU01_18410	COG1388	LysM domain
HYU01_18410	COG3409	Peptidoglycan-binding domain 1 protein
HYU01_18410	COG5632	N-Acetylmuramoyl-L-alanine amidase
HYU01_18415	COG4824	toxin secretion phage lysis holin
HYU01_18580	COG1595	DNA-templated transcription, initiation
HYU01_18625	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HYU01_18715	COG1396	sequence-specific DNA binding
HYU01_18740	COG0174	glutamine synthetase
HYU01_18745	COG0789	Transcriptional regulator
HYU01_18750	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HYU01_18755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HYU01_18760	COG2860	membrane
HYU01_18770	COG0464	growth
HYU01_18800	COG3584	3D domain protein
HYU01_18800	COG1388	LysM domain
HYU01_18805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HYU01_18805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HYU01_18805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HYU01_18810	COG1105	Belongs to the carbohydrate kinase PfkB family
HYU01_18815	COG1349	DNA-binding transcription factor activity
HYU01_18825	COG2322	membrane
HYU01_18840	COG1113	amino acid transport
HYU01_18855	COG1408	metallophosphoesterase
HYU01_18860	COG2116	formate transmembrane transporter activity
HYU01_18870	COG2217	Heavy metal translocating P-type atpase
HYU01_18875	COG2608	mercury ion transmembrane transporter activity
HYU01_18880	COG1937	Protein conserved in bacteria
HYU01_18890	COG2819	hydrolase of the alpha beta superfamily
HYU01_18895	COG1120	ATPase activity
HYU01_18900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_18905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_18920	COG2169	Transcriptional regulator
HYU01_18925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HYU01_18930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HYU01_18940	COG2364	Membrane
HYU01_18955	COG2267	carboxylic ester hydrolase activity
HYU01_18960	COG0346	lactoylglutathione lyase activity
HYU01_18965	COG5001	Diguanylate cyclase
HYU01_18965	COG3300	MHYT domain
HYU01_18980	COG1346	cytolysis
HYU01_18985	COG1380	Effector of murein hydrolase LrgA
HYU01_18990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HYU01_18995	COG0508	dehydrogenase complex catalyzes the overall conversion of
HYU01_18995	COG0596	Alpha beta hydrolase
HYU01_19000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HYU01_19015	COG1404	Belongs to the peptidase S8 family
HYU01_19020	COG3773	Cell wall hydrolase
HYU01_19025	COG0562	UDP-galactopyranose mutase
HYU01_19035	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HYU01_19045	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HYU01_19090	COG4550	Control of competence regulator ComK, YlbF/YmcA
HYU01_19095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HYU01_19100	COG1013	pyruvate-flavodoxin oxidoreductase activity
HYU01_19105	COG0674	pyruvate-flavodoxin oxidoreductase activity
HYU01_19105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HYU01_19115	COG2359	stage V sporulation protein S
HYU01_19120	COG1692	metallophosphoesterase
HYU01_19145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HYU01_19150	COG1426	Protein conserved in bacteria
HYU01_19165	COG0300	oxidoreductase activity
HYU01_19170	COG0612	Peptidase, M16
HYU01_19175	COG0612	Peptidase, M16
HYU01_19205	COG2188	Transcriptional regulator
HYU01_19210	COG1674	ftsk spoiiie
HYU01_19220	COG0740	serine-type endopeptidase activity
HYU01_19225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HYU01_19240	COG0527	aspartate kinase activity
HYU01_19245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HYU01_19250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HYU01_19255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HYU01_19260	COG1873	PFAM PRC-barrel domain
HYU01_19265	COG0612	Peptidase, M16
HYU01_19270	COG0726	polysaccharide deacetylase
HYU01_19285	COG0196	riboflavin kinase activity
HYU01_19290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HYU01_19300	COG1550	Protein conserved in bacteria
HYU01_19310	COG1358	cellular component organization or biogenesis
HYU01_19315	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HYU01_19320	COG0195	Participates in both transcription termination and antitermination
HYU01_19340	COG0750	zinc metalloprotease
HYU01_19345	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HYU01_19350	COG4589	Belongs to the CDS family
HYU01_19365	COG0528	UMP kinase activity
HYU01_19395	COG4974	Belongs to the 'phage' integrase family
HYU01_19405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HYU01_19415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HYU01_19455	COG1837	Belongs to the UPF0109 family
HYU01_19465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HYU01_19475	COG0552	protein localization to endoplasmic reticulum
HYU01_19480	COG1196	nuclear chromosome segregation
HYU01_19495	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_19500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HYU01_19515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HYU01_19520	COG1461	Dihydroxyacetone kinase
HYU01_19525	COG1302	Protein conserved in bacteria
HYU01_19540	COG1564	THIamine pyrophosphokinase
HYU01_19545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HYU01_19550	COG1162	GTPase activity
HYU01_19555	COG2815	serine threonine protein kinase
HYU01_19555	COG0515	serine threonine protein kinase
HYU01_19560	COG0631	protein serine/threonine phosphatase activity
HYU01_19570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HYU01_19570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HYU01_19580	COG0242	peptide deformylase activity
HYU01_19585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HYU01_19590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HYU01_19600	COG0194	GDP metabolic process
HYU01_19610	COG1561	YicC-like family, N-terminal region
HYU01_19615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HYU01_19625	COG0006	proline dipeptidase activity
HYU01_19640	COG3069	C4-dicarboxylate transmembrane transporter activity
HYU01_19680	COG0505	Belongs to the CarA family
HYU01_19705	COG0564	pseudouridine synthase activity
HYU01_19720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HYU01_19725	COG3599	regulation of cell shape
HYU01_19730	COG2302	S4 RNA-binding domain
HYU01_19735	COG0762	integral membrane protein
HYU01_19745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HYU01_19755	COG1873	PFAM PRC-barrel domain
HYU01_19760	COG1191	sigma factor activity
HYU01_19765	COG1191	sigma factor activity
HYU01_19775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HYU01_19780	COG0849	cell division
HYU01_19790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HYU01_19795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HYU01_19800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HYU01_19805	COG0772	Belongs to the SEDS family
HYU01_19820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HYU01_19825	COG0768	penicillin binding
HYU01_19835	COG4839	cell division protein FtsL
HYU01_19850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HYU01_19870	COG1399	metal-binding, possibly nucleic acid-binding protein
HYU01_19920	COG4824	toxin secretion phage lysis holin
HYU01_20010	COG1802	Transcriptional regulator
HYU01_20010	COG4626	Terminase
HYU01_20035	COG0582	viral genome integration into host DNA
HYU01_20130	COG1191	sigma factor activity
HYU01_20155	COG1484	DNA-dependent DNA replication
HYU01_20180	COG1396	sequence-specific DNA binding
HYU01_20200	COG1396	sequence-specific DNA binding
HYU01_20220	COG0582	viral genome integration into host DNA
HYU01_20230	COG3480	Lon protease (S16) C-terminal proteolytic domain
HYU01_20235	COG1752	Esterase of the alpha-beta hydrolase superfamily
HYU01_20240	COG3314	Sporulation integral membrane protein YlbJ
HYU01_20250	COG0742	ribosomal rna small subunit methyltransferase
HYU01_20265	COG3679	Belongs to the UPF0342 family
HYU01_20270	COG0406	alpha-ribazole phosphatase activity
HYU01_20285	COG2340	Cysteine-rich secretory protein family
HYU01_20300	COG3336	cytochrome c oxidase
HYU01_20335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HYU01_20340	COG0772	Belongs to the SEDS family
HYU01_20345	COG4838	Belongs to the UPF0358 family
HYU01_20350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HYU01_20355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HYU01_20365	COG4896	Protein conserved in bacteria
HYU01_20390	COG0483	inositol monophosphate 1-phosphatase activity
HYU01_20410	COG1982	Orn Lys Arg decarboxylase major
HYU01_20455	COG0022	dehydrogenase e1 component
HYU01_20460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HYU01_20470	COG0242	peptide deformylase activity
HYU01_20475	COG0561	phosphatase activity
HYU01_20485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HYU01_20490	COG0569	domain protein
HYU01_20510	COG0583	DNA-binding transcription factor activity
HYU01_20515	COG0517	IMP dehydrogenase activity
HYU01_20525	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HYU01_20535	COG4703	Protein of unknown function (DUF1797)
HYU01_20550	COG2200	EAL domain
HYU01_20555	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_20560	COG1408	metallophosphoesterase
HYU01_20605	COG2814	Major facilitator Superfamily
HYU01_20625	COG3209	COG3209 Rhs family protein
HYU01_20635	COG2205	protein histidine kinase activity
HYU01_20645	COG0436	Aminotransferase
HYU01_20650	COG1609	Transcriptional regulator
HYU01_20655	COG3833	ABC-type maltose transport systems, permease component
HYU01_20660	COG1175	transmembrane transport
HYU01_20665	COG2182	Extracellular solute-binding protein
HYU01_20675	COG0366	Alpha amylase catalytic
HYU01_20680	COG3842	ATPase activity
HYU01_20720	COG0183	Belongs to the thiolase family
HYU01_20755	COG1695	Transcriptional regulator
HYU01_20760	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_20780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HYU01_20785	COG0436	Aminotransferase
HYU01_20805	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HYU01_20825	COG3706	GGDEF domain
HYU01_20830	COG0778	Nitroreductase
HYU01_20855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HYU01_20855	COG2190	(PTS) system
HYU01_20855	COG1263	PTS System
HYU01_20860	COG3711	transcriptional antiterminator
HYU01_20880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HYU01_20905	COG1547	Domain of unknown function (DUF309)
HYU01_20910	COG0456	acetyltransferase
HYU01_20915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HYU01_20920	COG4086	secreted protein
HYU01_20925	COG0561	phosphatase activity
HYU01_20930	COG0697	spore germination
HYU01_20945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_20970	COG0733	neurotransmitter:sodium symporter activity
HYU01_20990	COG1686	Belongs to the peptidase S11 family
HYU01_20995	COG1725	Transcriptional regulator
HYU01_21000	COG1131	(ABC) transporter
HYU01_21015	COG1846	Transcriptional regulator
HYU01_21030	COG0598	Magnesium transport protein CorA
HYU01_21055	COG4974	Belongs to the 'phage' integrase family
HYU01_21065	COG0735	belongs to the Fur family
HYU01_21070	COG1300	Membrane
HYU01_21090	COG0667	Aldo Keto reductase
HYU01_21095	COG0656	L-ascorbic acid biosynthetic process
HYU01_21100	COG0456	acetyltransferase
HYU01_21100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HYU01_21110	COG0737	Belongs to the 5'-nucleotidase family
HYU01_21110	COG1525	nuclease
HYU01_21110	COG4085	toxin activity
HYU01_21120	COG0596	Alpha beta hydrolase
HYU01_21125	COG2056	Na+-H+ antiporter family
HYU01_21130	COG1609	Transcriptional regulator
HYU01_21135	COG0456	acetyltransferase
HYU01_21140	COG1073	alpha beta
HYU01_21155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HYU01_21155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HYU01_21160	COG0307	riboflavin synthase, alpha
HYU01_21180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HYU01_21185	COG4106	trans-aconitate 2-methyltransferase activity
HYU01_21190	COG2226	methyltransferase
HYU01_21190	COG1073	alpha beta
HYU01_21195	COG0156	8-amino-7-oxononanoate synthase activity
HYU01_21205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HYU01_21220	COG0737	Belongs to the 5'-nucleotidase family
HYU01_21230	COG1522	sequence-specific DNA binding
HYU01_21250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HYU01_21260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HYU01_21275	COG0300	oxidoreductase activity
HYU01_21280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_21285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HYU01_21290	COG1760	l-serine dehydratase
HYU01_21295	COG1760	l-serine dehydratase
HYU01_21315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HYU01_21325	COG2195	Cleaves the N-terminal amino acid of tripeptides
HYU01_21330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_21345	COG1376	ErfK ybiS ycfS ynhG family protein
HYU01_21350	COG4129	membrane
HYU01_21355	COG1126	abc transporter atp-binding protein
HYU01_21360	COG0765	amino acid transport
HYU01_21365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HYU01_21385	COG0772	Belongs to the SEDS family
HYU01_21390	COG0508	dehydrogenase complex catalyzes the overall conversion of
HYU01_21395	COG0022	dehydrogenase e1 component
HYU01_21400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HYU01_21405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HYU01_21415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HYU01_21420	COG0280	phosphate acetyltransferase
HYU01_21425	COG3829	transcription factor binding
HYU01_21425	COG3290	protein histidine kinase activity
HYU01_21435	COG0584	glycerophosphoryl diester phosphodiesterase
HYU01_21450	COG0745	RESPONSE REGULATOR receiver
HYU01_21455	COG0750	zinc metalloprotease
HYU01_21460	COG0497	DNA recombination
HYU01_21470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HYU01_21480	COG0142	geranyltranstransferase activity
HYU01_21505	COG1302	Protein conserved in bacteria
HYU01_21510	COG0439	Biotin carboxylase
HYU01_21515	COG0511	ligase activity, forming carbon-carbon bonds
HYU01_21555	COG3854	ATPases associated with a variety of cellular activities
HYU01_21580	COG0006	proline dipeptidase activity
HYU01_21595	COG3872	metal-dependent enzyme
HYU01_21605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HYU01_21625	COG0095	Lipoate-protein ligase
HYU01_21630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_21635	COG1609	Transcriptional regulator
HYU01_21645	COG2076	Multidrug Resistance protein
HYU01_21650	COG2076	Multidrug Resistance protein
HYU01_21685	COG1131	(ABC) transporter
HYU01_21690	COG1725	Transcriptional regulator
HYU01_21720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HYU01_21775	COG4970	Tfp pilus assembly protein FimT
HYU01_21785	COG1459	type II secretion system
HYU01_21790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HYU01_21840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HYU01_21850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HYU01_21850	COG0646	methionine synthase
HYU01_21855	COG0626	cystathionine gamma-synthase activity
HYU01_21860	COG0626	cystathionine gamma-synthase activity
HYU01_21885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_21895	COG1940	carbohydrate kinase activity
HYU01_21900	COG4483	Protein conserved in bacteria
HYU01_21905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HYU01_21915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HYU01_21925	COG0704	Plays a role in the regulation of phosphate uptake
HYU01_21930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HYU01_21935	COG0581	inorganic phosphate transmembrane transporter activity
HYU01_21940	COG0573	inorganic phosphate transmembrane transporter activity
HYU01_21945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HYU01_21955	COG0477	Major facilitator Superfamily
HYU01_21960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HYU01_21985	COG0735	belongs to the Fur family
HYU01_21990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HYU01_21995	COG1121	(ABC) transporter
HYU01_22000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_22030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HYU01_22035	COG2384	SAM-dependent methyltransferase
HYU01_22040	COG2010	Cytochrome c
HYU01_22045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HYU01_22050	COG0358	DNA primase activity
HYU01_22060	COG0517	IMP dehydrogenase activity
HYU01_22075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HYU01_22080	COG0295	cytidine deaminase activity
HYU01_22085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HYU01_22095	COG1480	7TM receptor with intracellular HD hydrolase
HYU01_22100	COG1702	phosphate starvation-inducible protein PhoH
HYU01_22115	COG1610	YqeY-like protein
HYU01_22125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HYU01_22130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HYU01_22150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HYU01_22160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HYU01_22165	COG1733	regulation of RNA biosynthetic process
HYU01_22190	COG1466	dna polymerase III delta subunit
HYU01_22205	COG2131	deaminase
HYU01_22210	COG1596	polysaccharide export
HYU01_22210	COG1555	photosystem II stabilization
HYU01_22215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HYU01_22220	COG2226	methyltransferase
HYU01_22225	COG0799	negative regulation of ribosome biogenesis
HYU01_22230	COG1713	HD superfamily hydrolase involved in NAD metabolism
HYU01_22240	COG1534	Rna-binding protein
HYU01_22250	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HYU01_22255	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HYU01_22270	COG1191	sigma factor activity
HYU01_22280	COG1595	DNA-templated transcription, initiation
HYU01_22290	COG0778	Nitroreductase
HYU01_22295	COG2357	RelA SpoT domain protein
HYU01_22305	COG1785	Belongs to the alkaline phosphatase family
HYU01_22315	COG2267	carboxylic ester hydrolase activity
HYU01_22350	COG1404	Belongs to the peptidase S8 family
HYU01_22365	COG3186	Phenylalanine-4-hydroxylase
HYU01_22375	COG2514	catechol 2,3-dioxygenase activity
HYU01_22380	COG2259	Doxx family
HYU01_22420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_22430	COG1454	alcohol dehydrogenase
HYU01_22430	COG1012	belongs to the aldehyde dehydrogenase family
HYU01_22435	COG0626	cystathionine gamma-synthase activity
HYU01_22440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HYU01_22465	COG0768	penicillin binding
HYU01_22495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HYU01_22515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HYU01_22525	COG0628	permease
HYU01_22545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HYU01_22555	COG0482	sulfurtransferase activity
HYU01_22560	COG1104	cysteine desulfurase activity
HYU01_22565	COG1959	2 iron, 2 sulfur cluster binding
HYU01_22570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HYU01_22580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HYU01_22590	COG0124	histidyl-tRNA synthetase
HYU01_22605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HYU01_22615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HYU01_22615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HYU01_22620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HYU01_22625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HYU01_22625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HYU01_22635	COG2244	polysaccharide biosynthetic process
HYU01_22640	COG2323	membrane
HYU01_22650	COG1862	Preprotein translocase
HYU01_22680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HYU01_22690	COG0697	spore germination
HYU01_22695	COG0697	spore germination
HYU01_22700	COG0640	Transcriptional regulator
HYU01_22725	COG0157	Belongs to the NadC ModD family
HYU01_22730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HYU01_22735	COG1104	cysteine desulfurase activity
HYU01_22740	COG1827	regulation of RNA biosynthetic process
HYU01_22745	COG2258	MOSC domain
HYU01_22750	COG0077	Prephenate dehydratase
HYU01_22755	COG0577	efflux transmembrane transporter activity
HYU01_22760	COG0577	efflux transmembrane transporter activity
HYU01_22765	COG1136	(ABC) transporter
HYU01_22770	COG5002	protein histidine kinase activity
HYU01_22780	COG0745	RESPONSE REGULATOR receiver
HYU01_22785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HYU01_22790	COG3290	protein histidine kinase activity
HYU01_22800	COG2868	ribosomal protein
HYU01_22810	COG1530	ribonuclease E activity
HYU01_22815	COG1994	Peptidase M50
HYU01_22820	COG0739	heme binding
HYU01_22825	COG2894	cell division
HYU01_22840	COG1792	Involved in formation and maintenance of cell shape
HYU01_22845	COG1077	Cell shape determining protein MreB Mrl
HYU01_22865	COG0285	dihydrofolate synthase activity
HYU01_22870	COG0525	valine-tRNA ligase activity
HYU01_22880	COG1388	LysM domain
HYU01_22890	COG0113	porphobilinogen synthase activity
HYU01_22895	COG1587	Uroporphyrinogen-III synthase
HYU01_22905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HYU01_22915	COG1846	Transcriptional regulator
HYU01_22920	COG1764	response to oxidative stress
HYU01_22935	COG0470	DNA polymerase III
HYU01_22935	COG1067	ATP-dependent peptidase activity
HYU01_22980	COG0622	Phosphoesterase
HYU01_22985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HYU01_22995	COG5401	PFAM Sporulation and spore germination
HYU01_23015	COG1309	transcriptional regulator
HYU01_23035	COG2197	response regulator
HYU01_23040	COG2233	PERMEase
HYU01_23050	COG0402	S-adenosylhomocysteine deaminase activity
HYU01_23055	COG0402	S-adenosylhomocysteine deaminase activity
HYU01_23075	COG0444	Belongs to the ABC transporter superfamily
HYU01_23080	COG4608	Belongs to the ABC transporter superfamily
HYU01_23085	COG3275	phosphorelay sensor kinase activity
HYU01_23090	COG3279	Response regulator of the LytR AlgR family
HYU01_23105	COG1983	PspC domain protein
HYU01_23110	COG1396	sequence-specific DNA binding
HYU01_23115	COG0697	spore germination
HYU01_23125	COG1959	2 iron, 2 sulfur cluster binding
HYU01_23130	COG1668	transmembrane transport
HYU01_23140	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HYU01_23150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HYU01_23155	COG1876	peptidase activity
HYU01_23160	COG0824	Thioesterase
HYU01_23165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HYU01_23170	COG1053	succinate dehydrogenase
HYU01_23175	COG2009	succinate dehydrogenase
HYU01_23180	COG1719	4-vinyl reductase, 4VR
HYU01_23190	COG3118	belongs to the thioredoxin family
HYU01_23195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HYU01_23200	COG2086	electron transfer activity
HYU01_23205	COG1024	Enoyl-CoA hydratase
HYU01_23210	COG1309	transcriptional regulator
HYU01_23215	COG0318	PFAM AMP-dependent synthetase and ligase
HYU01_23240	COG2318	DinB family
HYU01_23270	COG1131	(ABC) transporter
HYU01_23275	COG2205	protein histidine kinase activity
HYU01_23280	COG0745	RESPONSE REGULATOR receiver
HYU01_23290	COG4895	conserved protein (DUF2196)
HYU01_23295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HYU01_23310	COG4509	Sortase family
HYU01_23315	COG1120	ATPase activity
HYU01_23330	COG5386	Cell surface protein
HYU01_23340	COG5386	Cell surface protein
HYU01_23345	COG1114	Component of the transport system for branched-chain amino acids
HYU01_23350	COG1187	pseudouridine synthase activity
HYU01_23365	COG1796	DNA polymerase
HYU01_23365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HYU01_23370	COG1286	toxin biosynthetic process
HYU01_23400	COG0017	Asparaginyl-tRNA synthetase
HYU01_23405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_23405	COG0072	phenylalanine-tRNA ligase activity
HYU01_23415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HYU01_23425	COG1418	mRNA catabolic process
HYU01_23450	COG2814	Major facilitator Superfamily
HYU01_23455	COG1566	PFAM secretion protein HlyD family protein
HYU01_23460	COG1309	transcriptional regulator
HYU01_23465	COG1363	Peptidase, m42
HYU01_23485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HYU01_23490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HYU01_23500	COG1484	DNA-dependent DNA replication
HYU01_23505	COG3611	Membrane attachment protein
HYU01_23515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HYU01_23520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HYU01_23525	COG0237	dephospho-CoA kinase activity
HYU01_23530	COG1971	Probably functions as a manganese efflux pump
HYU01_23535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HYU01_23540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HYU01_23540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HYU01_23545	COG5002	protein histidine kinase activity
HYU01_23550	COG0745	RESPONSE REGULATOR receiver
HYU01_23575	COG0538	isocitrate dehydrogenase activity
HYU01_23580	COG0372	Belongs to the citrate synthase family
HYU01_23590	COG0628	permease
HYU01_23600	COG3030	protein affecting phage T7 exclusion by the F plasmid
HYU01_23625	COG1725	Transcriptional regulator
HYU01_23630	COG0281	malic enzyme
HYU01_23635	COG0587	DNA-directed DNA polymerase activity
HYU01_23650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HYU01_23670	COG4109	DRTGG domain
HYU01_23685	COG0006	proline dipeptidase activity
HYU01_23720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_23725	COG0662	Cupin 2, conserved barrel domain protein
HYU01_23735	COG1476	TRANSCRIPTIONal
HYU01_23750	COG1028	Short-chain dehydrogenase reductase Sdr
HYU01_23755	COG0589	response to stress
HYU01_23800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_23820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HYU01_23825	COG0827	DNA restriction-modification system
HYU01_23830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HYU01_23835	COG3874	Sporulation protein YtfJ
HYU01_23845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HYU01_23850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HYU01_23860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HYU01_23875	COG1104	cysteine desulfurase activity
HYU01_23885	COG0583	DNA-binding transcription factor activity
HYU01_23890	COG0697	spore germination
HYU01_23900	COG1956	GAF domain-containing protein
HYU01_23905	COG0626	cystathionine gamma-synthase activity
HYU01_23925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HYU01_23935	COG1595	DNA-templated transcription, initiation
HYU01_23945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HYU01_23950	COG0454	-acetyltransferase
HYU01_23955	COG0517	IMP dehydrogenase activity
HYU01_23960	COG0123	including yeast histone deacetylase and acetoin utilization protein
HYU01_23970	COG0745	RESPONSE REGULATOR receiver
HYU01_23980	COG0666	response to abiotic stimulus
HYU01_24015	COG1609	Transcriptional regulator
HYU01_24020	COG4851	CamS sex pheromone cAM373 precursor
HYU01_24025	COG3118	belongs to the thioredoxin family
HYU01_24035	COG2309	aminopeptidase activity
HYU01_24055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_24070	COG1674	ftsk spoiiie
HYU01_24080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_24085	COG4848	Belongs to the UPF0354 family
HYU01_24090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HYU01_24095	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HYU01_24100	COG1363	Peptidase, m42
HYU01_24110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_24125	COG0510	thiamine kinase activity
HYU01_24130	COG1523	belongs to the glycosyl hydrolase 13 family
HYU01_24140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HYU01_24145	COG1349	DNA-binding transcription factor activity
HYU01_24150	COG1187	pseudouridine synthase activity
HYU01_24155	COG2244	polysaccharide biosynthetic process
HYU01_24160	COG2081	HI0933 family
HYU01_24165	COG2814	Major facilitator Superfamily
HYU01_24175	COG3832	glyoxalase III activity
HYU01_24195	COG1329	Transcriptional regulator
HYU01_24205	COG4975	Glucose uptake
HYU01_24220	COG0314	molybdopterin synthase activity
HYU01_24225	COG1763	Mo-molybdopterin cofactor biosynthetic process
HYU01_24230	COG0303	'Molybdopterin
HYU01_24240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HYU01_24245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HYU01_24265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HYU01_24275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HYU01_24320	COG2814	Major facilitator Superfamily
HYU01_24325	COG0475	glutathione-regulated potassium exporter activity
HYU01_24330	COG0490	domain, Protein
HYU01_24335	COG0582	viral genome integration into host DNA
HYU01_24345	COG1136	(ABC) transporter
HYU01_24365	COG1242	4 iron, 4 sulfur cluster binding
HYU01_24370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HYU01_24375	COG1131	(ABC) transporter
HYU01_24385	COG1794	racemase activity, acting on amino acids and derivatives
HYU01_24405	COG2267	carboxylic ester hydrolase activity
HYU01_24410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HYU01_24415	COG0671	phosphoesterase, PA-phosphatase related
HYU01_24420	COG0438	transferase activity, transferring glycosyl groups
HYU01_24430	COG0521	Mo-molybdopterin cofactor biosynthetic process
HYU01_24480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HYU01_24485	COG5002	protein histidine kinase activity
HYU01_24490	COG4191	Histidine kinase
HYU01_24495	COG2267	carboxylic ester hydrolase activity
HYU01_24515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HYU01_24520	COG1116	anion transmembrane transporter activity
HYU01_24525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HYU01_24550	COG0494	nUDIX hydrolase
HYU01_24580	COG0288	reversible hydration of carbon dioxide
HYU01_24585	COG1271	oxidase subunit
HYU01_24590	COG1294	oxidase, subunit
HYU01_24615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_24640	COG1842	Phage shock protein A
HYU01_24675	COG5002	protein histidine kinase activity
HYU01_24680	COG0745	RESPONSE REGULATOR receiver
HYU01_24710	COG1597	lipid kinase activity
HYU01_24745	COG0586	Pfam SNARE associated Golgi protein
HYU01_24755	COG0577	efflux transmembrane transporter activity
HYU01_24760	COG1136	(ABC) transporter
HYU01_24765	COG2207	Transcriptional regulator
HYU01_24765	COG3708	Transcriptional regulator
HYU01_24770	COG0745	RESPONSE REGULATOR receiver
HYU01_24775	COG2205	protein histidine kinase activity
HYU01_24780	COG0577	efflux transmembrane transporter activity
HYU01_24785	COG0577	efflux transmembrane transporter activity
HYU01_24790	COG1136	(ABC) transporter
HYU01_24830	COG3964	amidohydrolase
HYU01_24860	COG4948	Mandelate Racemase Muconate Lactonizing
HYU01_24870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HYU01_24875	COG0596	Alpha beta hydrolase
HYU01_24880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HYU01_24885	COG1169	isochorismate synthase
HYU01_24895	COG1575	Belongs to the MenA family. Type 1 subfamily
HYU01_24900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HYU01_24905	COG1278	Cold shock
HYU01_24925	COG0058	SHG alpha-glucan phosphorylase activity
HYU01_24930	COG0297	glycogen (starch) synthase activity
HYU01_24935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HYU01_24940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HYU01_24955	COG0039	L-malate dehydrogenase activity
HYU01_25050	COG0544	peptidyl-prolyl cis-trans isomerase activity
HYU01_25085	COG1285	pathogenesis
HYU01_25090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HYU01_25100	COG0166	Belongs to the GPI family
HYU01_25105	COG2155	Conserved Protein
HYU01_25110	COG1098	S1 RNA binding domain
HYU01_25115	COG0436	Aminotransferase
HYU01_25120	COG1522	sequence-specific DNA binding
HYU01_25125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HYU01_25130	COG2267	carboxylic ester hydrolase activity
HYU01_25140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HYU01_25160	COG5018	Exonuclease
HYU01_25165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HYU01_25180	COG0423	glycine-tRNA ligase activity
HYU01_25185	COG2050	protein possibly involved in aromatic compounds catabolism
HYU01_25195	COG1268	BioY protein
HYU01_25205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HYU01_25210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HYU01_25225	COG3584	3D domain protein
HYU01_25240	COG1252	NADH dehydrogenase
HYU01_25255	COG3708	Transcriptional regulator
HYU01_25270	COG1683	Conserved Protein
HYU01_25285	COG0316	Belongs to the HesB IscA family
HYU01_25300	COG1252	NADH dehydrogenase
HYU01_25310	COG2274	protein secretion by the type I secretion system
HYU01_25315	COG0390	transport system, permease component
HYU01_25320	COG2824	Alkylphosphonate utilization operon protein PhnA
HYU01_25360	COG4837	Protein of unknown function (DUF1462)
HYU01_25365	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HYU01_25375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HYU01_25380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HYU01_25395	COG2249	NAD(P)H dehydrogenase (quinone) activity
HYU01_25400	COG0647	UMP catabolic process
HYU01_25410	COG2445	Protein of unknown function DUF86
HYU01_25415	COG1494	fructose-1,6-bisphosphatase
HYU01_25430	COG4470	Protein conserved in bacteria
HYU01_25440	COG0789	Transcriptional regulator
HYU01_25445	COG4377	Putative membrane peptidase family (DUF2324)
HYU01_25470	COG0739	heme binding
HYU01_25480	COG3377	Domain of unknown function (DUF1805)
HYU01_25485	COG0737	Belongs to the 5'-nucleotidase family
HYU01_25495	COG1695	Transcriptional regulator
HYU01_25505	COG0719	Fe-S assembly protein
HYU01_25510	COG0822	iron-sulfur transferase activity
HYU01_25515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HYU01_25520	COG0719	Fe-S assembly protein
HYU01_25525	COG0396	ATPase activity
HYU01_25530	COG1464	Belongs to the NlpA lipoprotein family
HYU01_25535	COG1464	Belongs to the NlpA lipoprotein family
HYU01_25540	COG2011	ABC-type metal ion transport system permease component
HYU01_25545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HYU01_25555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HYU01_25560	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HYU01_25575	COG1393	Belongs to the ArsC family
HYU01_25620	COG0039	L-malate dehydrogenase activity
HYU01_25645	COG1309	transcriptional regulator
HYU01_25650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HYU01_25655	COG1960	acyl-CoA dehydrogenase activity
HYU01_25665	COG0183	Belongs to the thiolase family
HYU01_25670	COG1250	3-hydroxyacyl-CoA dehydrogenase
HYU01_25670	COG1024	Enoyl-CoA hydratase
HYU01_25680	COG1686	Belongs to the peptidase S11 family
HYU01_25695	COG0011	TIGRFAM Protein of
HYU01_25700	COG0840	transmembrane signaling receptor activity
HYU01_25720	COG2814	Major facilitator Superfamily
HYU01_25725	COG0531	amino acid
HYU01_25735	COG0706	membrane insertase activity
HYU01_25745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HYU01_25780	COG0586	Pfam SNARE associated Golgi protein
HYU01_25790	COG1376	ErfK ybiS ycfS ynhG family protein
HYU01_25795	COG0745	RESPONSE REGULATOR receiver
HYU01_25800	COG5002	protein histidine kinase activity
HYU01_25810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HYU01_25825	COG2151	metal-sulfur cluster biosynthetic enzyme
HYU01_25830	COG3227	Zinc metalloprotease (Elastase)
HYU01_25840	COG1741	Belongs to the pirin family
HYU01_25855	COG0475	glutathione-regulated potassium exporter activity
HYU01_25860	COG0490	domain, Protein
HYU01_25870	COG1115	amino acid carrier protein
HYU01_25875	COG0783	Belongs to the Dps family
HYU01_25890	COG1611	Belongs to the LOG family
HYU01_25905	COG2311	Membrane
HYU01_25915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_25920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_25925	COG1115	amino acid carrier protein
HYU01_25930	COG1115	amino acid carrier protein
HYU01_25935	COG2910	NAD(P)H-binding
HYU01_25950	COG0656	L-ascorbic acid biosynthetic process
HYU01_25955	COG2814	Major facilitator Superfamily
HYU01_25960	COG1733	regulation of RNA biosynthetic process
HYU01_25970	COG1252	NADH dehydrogenase
HYU01_25975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HYU01_25980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HYU01_25990	COG3290	protein histidine kinase activity
HYU01_25990	COG0840	transmembrane signaling receptor activity
HYU01_26000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HYU01_26005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HYU01_26020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HYU01_26025	COG3223	Belongs to the PsiE family
HYU01_26070	COG0557	exoribonuclease II activity
HYU01_26075	COG1647	Serine aminopeptidase, S33
HYU01_26080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HYU01_26085	COG1346	cytolysis
HYU01_26180	COG4695	Portal protein
HYU01_26200	COG4974	Belongs to the 'phage' integrase family
HYU01_26215	COG0149	triose-phosphate isomerase activity
HYU01_26225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HYU01_26240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HYU01_26270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HYU01_26285	COG2323	membrane
HYU01_26290	COG0740	serine-type endopeptidase activity
HYU01_26295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HYU01_26305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HYU01_26315	COG1051	belongs to the nudix hydrolase family
HYU01_26325	COG0492	ferredoxin-NADP+ reductase activity
HYU01_26330	COG0457	Tetratricopeptide repeat
HYU01_26335	COG0110	maltose O-acetyltransferase activity
HYU01_26355	COG1950	PFAM Membrane protein of
HYU01_26365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HYU01_26370	COG0556	nucleotide-excision repair
HYU01_26390	COG0789	Transcriptional regulator
HYU01_26415	COG2855	membrane
HYU01_26420	COG0583	DNA-binding transcription factor activity
HYU01_26430	COG0655	NAD(P)H dehydrogenase (quinone) activity
HYU01_26445	COG1132	(ABC) transporter
HYU01_26450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HYU01_26455	COG3409	Peptidoglycan-binding domain 1 protein
HYU01_26455	COG0793	Belongs to the peptidase S41A family
HYU01_26460	COG2177	Part of the ABC transporter FtsEX involved in
HYU01_26465	COG2884	Cell division ATP-binding protein ftsE
HYU01_26475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HYU01_26485	COG0653	protein targeting
HYU01_26490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HYU01_26495	COG1278	Cold shock
HYU01_26500	COG1040	competence protein
HYU01_26505	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HYU01_26510	COG1388	LysM domain
HYU01_26510	COG0791	NLP P60 protein
HYU01_26515	COG1733	regulation of RNA biosynthetic process
HYU01_26520	COG1307	EDD domain protein, DegV family
HYU01_26525	COG1739	Uncharacterized protein family UPF0029
HYU01_26530	COG1316	TRANSCRIPTIONal
HYU01_26535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HYU01_26540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HYU01_26545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HYU01_26555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HYU01_26555	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HYU01_26570	COG3394	polysaccharide catabolic process
HYU01_26575	COG1486	melibiose metabolic process
HYU01_26580	COG1447	Phosphotransferase system cellobiose-specific component IIA
HYU01_26585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HYU01_26595	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HYU01_26600	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HYU01_26605	COG1447	Phosphotransferase system cellobiose-specific component IIA
HYU01_26615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HYU01_26620	COG1301	dicarboxylic acid transport
HYU01_26630	COG0346	lactoylglutathione lyase activity
HYU01_26635	COG1511	domain protein
HYU01_26640	COG0583	DNA-binding transcription factor activity
HYU01_26645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HYU01_26665	COG1271	oxidase subunit
HYU01_26670	COG1294	oxidase, subunit
HYU01_26675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HYU01_26685	COG1620	l-lactate permease
HYU01_26695	COG2389	metal-binding protein
HYU01_26705	COG1368	sulfuric ester hydrolase activity
HYU01_26725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HYU01_26735	COG1215	transferase activity, transferring glycosyl groups
HYU01_26745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HYU01_26750	COG3584	3D domain protein
HYU01_26750	COG1388	LysM domain
HYU01_26775	COG4715	Zinc finger, swim domain protein
HYU01_26780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HYU01_26815	COG1191	sigma factor activity
HYU01_26825	COG0577	efflux transmembrane transporter activity
HYU01_26830	COG1136	(ABC) transporter
HYU01_26865	COG5002	protein histidine kinase activity
HYU01_26870	COG0745	RESPONSE REGULATOR receiver
HYU01_26875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HYU01_26900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HYU01_26905	COG1134	teichoic acid transport
HYU01_26910	COG1682	transport, permease protein
HYU01_26915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HYU01_26955	COG1609	Transcriptional regulator
HYU01_26970	COG0739	heme binding
HYU01_26985	COG3279	Response regulator of the LytR AlgR family
HYU01_26990	COG4555	ABC transporter
HYU01_26995	COG2385	sporulation resulting in formation of a cellular spore
HYU01_27000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HYU01_27010	COG4836	Membrane
HYU01_27015	COG1007	ATP synthesis coupled electron transport
HYU01_27020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HYU01_27025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HYU01_27035	COG0839	Belongs to the complex I subunit 6 family
HYU01_27050	COG0649	NAD binding
HYU01_27055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HYU01_27065	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HYU01_27070	COG3300	MHYT domain
HYU01_27070	COG5001	Diguanylate cyclase
HYU01_27120	COG0356	it plays a direct role in the translocation of protons across the membrane
HYU01_27155	COG0698	ribose 5-phosphate isomerase
HYU01_27165	COG2190	(PTS) system
HYU01_27170	COG2259	Doxx family
HYU01_27175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HYU01_27195	COG0009	L-threonylcarbamoyladenylate synthase
HYU01_27210	COG2890	protein-(glutamine-N5) methyltransferase activity
HYU01_27215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HYU01_27235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HYU01_27240	COG1494	fructose-1,6-bisphosphatase
HYU01_27245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HYU01_27260	COG4821	SIS domain
HYU01_27270	COG3343	RNA polymerase activity
HYU01_27280	COG1960	acyl-CoA dehydrogenase activity
HYU01_27285	COG1960	acyl-CoA dehydrogenase activity
HYU01_27290	COG1250	3-hydroxyacyl-CoA dehydrogenase
HYU01_27295	COG0183	Belongs to the thiolase family
HYU01_27300	COG0247	lactate metabolic process
HYU01_27300	COG2181	nitrate reductase activity
HYU01_27305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HYU01_27315	COG3300	MHYT domain
HYU01_27315	COG5001	Diguanylate cyclase
HYU01_27330	COG2197	response regulator
HYU01_27335	COG4585	Histidine kinase
HYU01_27340	COG0842	Transport permease protein
HYU01_27345	COG1131	(ABC) transporter
HYU01_27350	COG0024	Methionine aminopeptidase
HYU01_27365	COG2234	aminopeptidase activity
HYU01_27385	COG1595	DNA-templated transcription, initiation
HYU01_27390	COG0018	arginyl-trna synthetase
HYU01_27395	COG4506	Protein conserved in bacteria
HYU01_27400	COG1619	proteins homologs of microcin C7 resistance protein MccF
HYU01_27420	COG0010	Belongs to the arginase family
HYU01_27425	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HYU01_27430	COG2814	Major facilitator Superfamily
HYU01_27435	COG0789	Transcriptional regulator
HYU01_27440	COG0584	glycerophosphoryl diester phosphodiesterase
HYU01_27445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HYU01_27455	COG1994	Peptidase M50
HYU01_27465	COG1078	dGTPase activity
HYU01_27470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HYU01_27475	COG1120	ATPase activity
HYU01_27480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_27485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HYU01_27505	COG0095	Lipoate-protein ligase
HYU01_27510	COG0280	phosphate acetyltransferase
HYU01_27525	COG3773	Cell wall hydrolase
HYU01_27535	COG2363	Small membrane protein
HYU01_27545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HYU01_27550	COG2233	PERMEase
HYU01_27555	COG0561	phosphatase activity
HYU01_27560	COG2814	Major facilitator Superfamily
HYU01_27570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HYU01_27575	COG1131	(ABC) transporter
HYU01_27580	COG2755	lipolytic protein G-D-S-L family
HYU01_27585	COG1609	Transcriptional regulator
HYU01_27595	COG0460	homoserine dehydrogenase
HYU01_27615	COG1011	Hydrolase
HYU01_27620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HYU01_27635	COG2197	response regulator
HYU01_27645	COG0351	phosphomethylpyrimidine kinase
HYU01_27650	COG3706	GGDEF domain
HYU01_27655	COG2879	small protein
HYU01_27660	COG1966	Carbon starvation protein
HYU01_27665	COG3279	Response regulator of the LytR AlgR family
HYU01_27670	COG0477	Major facilitator Superfamily
HYU01_27695	COG0840	transmembrane signaling receptor activity
HYU01_27705	COG1607	acyl-coa hydrolase
HYU01_27720	COG0488	(ABC) transporter
HYU01_27745	COG0463	Glycosyl transferase, family 2
HYU01_27750	COG1309	transcriptional regulator
HYU01_27755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HYU01_27760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HYU01_27760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HYU01_27765	COG0628	permease
HYU01_27780	COG3279	Response regulator of the LytR AlgR family
HYU01_27785	COG3275	phosphorelay sensor kinase activity
HYU01_27790	COG2814	Major facilitator Superfamily
HYU01_27795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HYU01_27800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HYU01_27805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HYU01_27825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HYU01_27830	COG1272	protein, Hemolysin III
HYU01_27855	COG1164	Oligoendopeptidase f
HYU01_27875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HYU01_27880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HYU01_27885	COG4853	Protein conserved in bacteria
HYU01_27890	COG4863	YycH protein
HYU01_27895	COG5002	protein histidine kinase activity
HYU01_27900	COG0745	RESPONSE REGULATOR receiver
HYU01_27930	COG0305	Participates in initiation and elongation during chromosome replication
HYU01_27940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HYU01_27945	COG4241	membrane
HYU01_27955	COG0629	single-stranded DNA binding
HYU01_27965	COG0012	GTP binding
HYU01_27970	COG4481	Protein conserved in bacteria
HYU01_27975	COG0668	transmembrane transport
HYU01_27985	COG1475	DNA binding
HYU01_27990	COG1192	Involved in chromosome partitioning
HYU01_28010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HYU01_28015	COG1847	R3H domain protein
HYU01_28020	COG0706	membrane insertase activity
HYU01_28085	COG3344	reverse transcriptase
HYU01_28185	COG3344	reverse transcriptase
HYU01_28405	COG4962	Type ii secretion system protein e
HYU01_28550	COG2311	Membrane
HYU01_28580	COG4196	transglutaminase domain protein
HYU01_28585	COG0671	phosphoesterase, PA-phosphatase related
HYU01_28610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HYU01_28615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HYU01_28635	COG2801	Transposase and inactivated derivatives
HYU01_28830	COG2002	toxin-antitoxin pair type II binding
HYU01_28840	COG4974	Belongs to the 'phage' integrase family
HYU01_28885	COG2801	Transposase and inactivated derivatives
HYU01_28910	COG3443	Belongs to the bacterial solute-binding protein 9 family
HYU01_28920	COG4974	Belongs to the 'phage' integrase family
HYU01_28945	COG0457	Tetratricopeptide repeat
HYU01_28955	COG1923	regulation of RNA biosynthetic process
HYU01_29200	COG1192	Involved in chromosome partitioning
HYU01_29220	COG2801	Transposase and inactivated derivatives
HYU01_29250	COG1683	Conserved Protein
HYU01_29255	COG1309	transcriptional regulator
HYU01_29340	COG0681	Belongs to the peptidase S26 family
HYU01_29370	COG1280	lysine exporter protein (LysE YggA)
HYU01_29405	COG4166	transmembrane transport
HYU01_29425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII