locus-tag class description BF37_1003 ENOG4105F1A Pyruvate formate-lyase BF37_1006 ENOG4105C3I Nad-dependent epimerase dehydratase BF37_1007 ENOG4107QQG Dehydrogenase BF37_1009 ENOG4105CKK Glycosyl transferase, family 2 BF37_1012 ENOG4108A04 Beta-lactamase BF37_1014 ENOG4105CSV Glutaminase BF37_1020 ENOG4108IQI permease BF37_1022 ENOG4108JUB Transcriptional regulator BF37_1024 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BF37_105 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BF37_1082 ENOG4105VTR Integrase BF37_1083 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF37_1091 ENOG4105UPD Calcium Proton BF37_1092 ENOG410606W general stress protein BF37_1095 ENOG4107ZTW SNARE associated Golgi BF37_1098 ENOG4105C3F Signal peptidase i BF37_110 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BF37_1100 ENOG4108IPJ Membrane BF37_1101 ENOG4105C59 p-type ATPase BF37_1102 ENOG4107U9T Pfam:Ribonuclease_BN BF37_1104 ENOG4105KJF protein tyrosine phosphatase BF37_1108 ENOG4108TTB tellurium resistance protein BF37_1109 ENOG4107TS3 membrane protein, TerC BF37_1110 ENOG4106FN3 tellurium resistance protein BF37_1111 ENOG4106FN3 tellurium resistance protein BF37_1112 ENOG4108N0M stress protein BF37_1115 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BF37_1118 ENOG4105DEU major facilitator superfamily BF37_112 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BF37_1122 ENOG41062JF Transcriptional regulator BF37_1127 ENOG4105C5H ABC transporter BF37_113 ENOG4108ZP8 Acetolactate synthase small subunit BF37_1130 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF37_1133 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BF37_1139 ENOG4105CI1 PTS System BF37_114 ENOG4105C7K acetolactate synthase BF37_1141 ENOG4105C8Q Methyl-accepting chemotaxis BF37_1142 ENOG4105C8Q Methyl-accepting chemotaxis BF37_1144 ENOG4105EAB amino acid AbC transporter BF37_1145 ENOG4105E5Q amino acid AbC transporter BF37_1148 ENOG4105D2S major facilitator superfamily BF37_1149 ENOG410756H nucleotidyltransferase BF37_115 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF37_1153 ENOG4105BZU Histidine kinase BF37_1157 ENOG4106UIA BF37_1158 ENOG4106UIA BF37_1162 ENOG4108V5C ABC transporter BF37_1163 ENOG4105DQ5 transport system permease protein BF37_1164 ENOG4105EHG Permease protein BF37_1165 ENOG4107W7X Aldolase BF37_1167 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BF37_1168 ENOG4105D3R alkyl hydroperoxide reductase BF37_1173 ENOG4105DFD Na H antiporter BF37_1174 ENOG4105DTQ mandelate racemase muconate lactonizing BF37_1177 ENOG4108W15 Protein of unknown function (DUF1456) BF37_1180 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF37_1181 ENOG4105D9N nucleoside BF37_1185 ENOG4105KPY Small multidrug resistance protein BF37_1186 ENOG4105C26 Dehydrogenase BF37_1188 ENOG4108JPW Aminotransferase BF37_1189 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BF37_1190 ENOG4105CBD Diacylglycerol kinase BF37_1194 ENOG4107I77 yiaA/B two helix domain BF37_1195 ENOG410834F Transcriptional regulator BF37_1196 ENOG4105D0U Arsenite-activated ATPase (ArsA) BF37_120 ENOG4105KBJ sporulation protein ytfj BF37_1200 ENOG4105D01 (LipO)protein BF37_1201 ENOG4108UMI ABC transporter, permease BF37_1202 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BF37_1203 ENOG4108W2Y isochorismatase BF37_1209 ENOG4105C4R Atp-dependent dna helicase BF37_121 ENOG41063Y9 BF37_1214 ENOG4105C12 Phosphoribosylglycinamide synthetase BF37_1216 ENOG4108V3E phosphoribosylglycinamide formyltransferase BF37_122 ENOG4105CZN Potassium uptake protein BF37_1221 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BF37_1223 ENOG4105C83 adenylosuccinate lyase BF37_1224 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BF37_1225 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BF37_1230 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_1234 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BF37_1239 ENOG4108SHN Glycosyl transferase, family 2 BF37_1244 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF37_1252 ENOG4105BZU Histidine kinase BF37_1254 ENOG4105C7N Xanthine uracil vitamin C permease BF37_1258 ENOG4108TYN CAAX amino terminal protease family protein BF37_1261 ENOG4105C5H ABC transporter BF37_1262 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF37_1263 ENOG410801F ribosomal-protein-alanine acetyltransferase BF37_1264 ENOG41072GX Peptidase M22 Glycoprotease BF37_1265 ENOG4105K8N protein family UPF0079, ATPase BF37_128 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BF37_1285 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BF37_1287 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF37_1288 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BF37_129 ENOG4107QMU Mate efflux family protein BF37_1291 ENOG4107ZXI Rhomboid family BF37_1293 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF37_1294 ENOG4105CPF Cell wall formation (By similarity) BF37_1295 ENOG4105CPF Cell wall formation (By similarity) BF37_1296 ENOG4108SC4 )-transporter BF37_1298 ENOG4105ERH Fumarylacetoacetate hydrolase BF37_1299 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BF37_1306 ENOG410667J hydrolase BF37_1307 ENOG4108JQ7 (ABC) transporter BF37_1308 ENOG4105C3U ABC transporter BF37_1309 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF37_1311 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BF37_1314 ENOG4105C5H ABC transporter BF37_1318 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BF37_1319 ENOG4108RE7 deoxyribonuclease BF37_1322 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF37_1326 ENOG4105F6E Acyl-transferase BF37_1330 ENOG4105EGI Transcriptional regulator BF37_1333 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BF37_1334 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF37_1335 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF37_1336 ENOG4105E0C molybdate abc transporter BF37_1338 ENOG4107XDY Nicotinamide Mononucleotide Transporter BF37_1339 ENOG4105II7 pyrroline-5-carboxylate reductase BF37_1341 ENOG4108J59 Extracellular solute-binding protein, family 5 BF37_1342 ENOG4108J59 Extracellular solute-binding protein, family 5 BF37_1348 ENOG4108JQ7 (ABC) transporter BF37_1349 ENOG4105C3U ABC transporter BF37_1350 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF37_1351 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF37_1354 ENOG4105C2C drug resistance transporter, Bcr CflA BF37_1357 ENOG4105IQ5 FAD linked oxidase domain protein BF37_1359 ENOG4105EE1 crotonyl-CoA reductase BF37_136 ENOG4105NQC Flavodoxin BF37_1360 ENOG4105D01 (LipO)protein BF37_1361 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BF37_1362 ENOG4108UMI ABC transporter, permease BF37_1363 ENOG4108PSK reductase BF37_1371 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BF37_1372 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BF37_1374 ENOG4105CMG Carbohydrate kinase BF37_1375 ENOG4105CMG Carbohydrate kinase BF37_1377 ENOG4108VQT Alpha beta hydrolase fold protein BF37_1378 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BF37_1380 ENOG4107U5W ybbr family BF37_1381 ENOG4105C8B TIGR00159 family BF37_1399 ENOG4108NMV polysaccharide deacetylase BF37_1402 ENOG4105D1F ATP-binding protein BF37_1407 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BF37_1408 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF37_1409 ENOG4108JJB ABC transporter BF37_141 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF37_1415 ENOG41067V7 50S ribosomal protein L36 BF37_1417 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF37_1419 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF37_1424 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BF37_143 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF37_144 ENOG4105EA8 2-Nitropropane dioxygenase BF37_1445 ENOG4105XPM ribosomal protein BF37_1446 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BF37_1448 ENOG4107Y49 methyltransferase BF37_145 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF37_1453 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BF37_1455 ENOG4105QIV RNA polymerase BF37_1456 ENOG4105M0M Tetracycline resistance protein BF37_1457 ENOG4105C2N RNA methyltransferase TrmH family group 3 BF37_1460 ENOG4105D7W serine acetyltransferase BF37_1464 ENOG4105CTP PilT protein domain protein BF37_1466 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BF37_1469 ENOG4108Z0C Uvrb UvrC protein BF37_1476 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BF37_1478 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BF37_1479 ENOG4105KRF dihydroneopterin aldolase BF37_1480 ENOG4105EEI dihydropteroate synthase BF37_1481 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BF37_1482 ENOG4105DDQ anthranilate synthase BF37_1483 ENOG4105CRQ synthase (Component I) BF37_1484 ENOG4105C6T cysteine synthase BF37_1487 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BF37_1488 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF37_1489 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BF37_1493 ENOG41060GV RNA binding s1 domain protein BF37_1496 ENOG4105VYY sporulation protein yabp BF37_1497 ENOG41082I2 s4 domain protein BF37_1498 ENOG4108IY2 MazG family BF37_1500 ENOG4108M14 stage v sporulation protein t BF37_1501 ENOG4108JA2 transcriptioN-repair coupling factor BF37_1503 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BF37_1504 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BF37_1507 ENOG4105KME endoribonuclease L-psp BF37_1508 ENOG4105DFT pur operon repressor BF37_1511 ENOG4105W42 Veg protein BF37_1512 ENOG4105XFA sporulation peptidase YabG BF37_1514 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BF37_1515 ENOG4105F8V Hydrolase, tatD family BF37_1517 ENOG4105KRN Transcriptional regulator, abrb family BF37_1518 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BF37_1520 ENOG41060K3 Methyltransferase BF37_1522 ENOG4105MA4 psp1 domain protein BF37_1523 ENOG4105FA2 dna polymerase iii BF37_1525 ENOG4105CXN decarboxylase BF37_153 ENOG4105CJ1 ABC, transporter BF37_1533 ENOG41067KS pro-sigma K processing BF37_1537 ENOG4105C6E dna polymerase iii BF37_1538 ENOG4108Z6B deaminase BF37_1539 ENOG4105GTG Isochorismatase BF37_1541 ENOG4105ZMH deoxynucleoside kinase BF37_1548 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BF37_155 ENOG4105CZV ABC transporter BF37_1556 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF37_1559 ENOG410848D S4 domain protein YaaA BF37_156 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF37_1560 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF37_1564 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF37_1566 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BF37_157 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF37_1570 ENOG4107QJE Chromosome Partitioning Protein BF37_1571 ENOG4105FA0 parb-like partition protein BF37_1572 ENOG4108ZDA Sporulation protein YyaC BF37_1573 ENOG4105D8X mechanosensitive ion channel BF37_1574 ENOG4105VDK protein, conserved in bacteria BF37_1575 ENOG4105C3G gtp-binding protein BF37_1577 ENOG4108UUM single-stranded DNA-binding protein BF37_1579 ENOG4108XMW Membrane BF37_158 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF37_1580 ENOG4105BZR domain protein BF37_1582 ENOG4105CDU Replicative dna helicase BF37_1588 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_1589 ENOG4105BZU Histidine kinase BF37_1592 ENOG4105Q2H domain protein BF37_1593 ENOG4105C0H protease BF37_1597 ENOG4105DPN Oligoendopeptidase f BF37_16 ENOG4107RB3 L-asparaginase BF37_160 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF37_1600 ENOG4105C1J atp-dependent rna helicase BF37_1602 ENOG4108UT2 hemolysin iii BF37_1603 ENOG4105CMR udp-glucose 4-epimerase BF37_1605 ENOG4105IW1 AmiS UreI transporter BF37_1607 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF37_161 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BF37_1610 ENOG4107RGD Major Facilitator superfamily BF37_1611 ENOG4108HRK Histidine kinase BF37_1612 ENOG4105DY9 regulatoR BF37_1615 ENOG4106F5Q Membrane BF37_1616 ENOG4105E0X reductase BF37_1618 ENOG41067SE Tetr family transcriptional regulator BF37_1619 ENOG4105CKK Glycosyl transferase, family 2 BF37_1624 ENOG4105C5H ABC transporter BF37_1625 ENOG4105JEU Glycosyl transferase, family 2 BF37_1627 ENOG4108S4H thioesterase Superfamily protein BF37_1629 ENOG4106YBV Methyl-accepting chemotaxis BF37_1630 ENOG4105EN6 Membrane BF37_1634 ENOG41079KZ Major Facilitator Superfamily BF37_1635 ENOG4105DY9 regulatoR BF37_1636 ENOG4105D22 carbon starvation protein BF37_1637 ENOG4105VCD cytoplasmic protein BF37_1638 ENOG4105BZU Histidine kinase BF37_1639 ENOG4105DWF phosphomethylpyrimidine kinase BF37_1640 ENOG4105BZU Histidine kinase BF37_1641 ENOG4105BZU Histidine kinase BF37_1642 ENOG4105WH1 Two component transcriptional regulator luxr family BF37_1644 ENOG4108Y4K DNA-binding transcriptional activator BF37_1650 ENOG4105D6E homoserine dehydrogenase BF37_1653 ENOG41090WU lipolytic protein G-D-S-L family BF37_1654 ENOG4105CJ1 ABC, transporter BF37_1655 ENOG4108TU7 Inherit from COG: (ABC) transporter BF37_1657 ENOG4105VCH membrane BF37_1658 ENOG410667J hydrolase BF37_1660 ENOG4107SVH Potassium channel protein BF37_1664 ENOG4108VKI Cell wall hydrolase BF37_1667 ENOG4108IJ2 phosphate acetyltransferase BF37_1670 ENOG4108VCI transcription factor, rsfa family BF37_1672 ENOG4105DQ5 transport system permease protein BF37_1673 ENOG4105DQ5 transport system permease protein BF37_1674 ENOG4105EHG Permease protein BF37_1675 ENOG4105E0A ABC, transporter BF37_1676 ENOG4108MES Periplasmic binding protein BF37_1677 ENOG4105DCI Phosphohydrolase BF37_1678 ENOG41069HH 4-oxalocrotonate tautomerase BF37_1679 ENOG4108Z4T Peptidase M50 BF37_1680 ENOG4108XFG YwhD family BF37_1681 ENOG4105BZ4 penicillin-binding protein BF37_1682 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF37_1683 ENOG4107SWG transcriptional regulator MERR family BF37_1684 ENOG4105DXB Major Facilitator superfamily BF37_1686 ENOG4105CYW agmatinase BF37_169 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BF37_1690 ENOG410684U Domain of unknown function (DUF1934) BF37_1692 ENOG4105EMN RNA polymerase sigma factor BF37_1696 ENOG4105IIU Aminopeptidase BF37_17 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BF37_170 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BF37_1700 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BF37_1701 ENOG4108M15 ABC transporter BF37_1702 ENOG4105KCT ABC transporter BF37_1703 ENOG4105BZU Histidine kinase BF37_1708 ENOG4105BZU Histidine kinase BF37_1711 ENOG4105DF6 Fe-S oxidoreductase BF37_1713 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BF37_1714 ENOG4105C1G acyl-Coa dehydrogenase BF37_1715 ENOG4105C1G acyl-Coa dehydrogenase BF37_172 ENOG4105BZU Histidine kinase BF37_1722 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BF37_1723 ENOG4105CBT Fructose-1,6-bisphosphatase BF37_1724 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BF37_1727 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BF37_1728 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BF37_1729 ENOG4108ZXQ stage ii sporulation protein r BF37_1731 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF37_1734 ENOG4107XC4 flavin reductase domain protein, FMN-binding BF37_1735 ENOG4108VGI doxx family BF37_1738 ENOG4108YZG isomerase BF37_174 ENOG4106DF1 BF37_1743 ENOG41062M3 atp synthase BF37_1744 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BF37_1754 ENOG4105BZU Histidine kinase BF37_1755 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BF37_1757 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BF37_1758 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BF37_176 ENOG41090MY MarR family Transcriptional regulator BF37_1763 ENOG4105D65 subunit l BF37_1764 ENOG4105C8S subunit m BF37_1765 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BF37_1766 ENOG4106778 Protein of unknown function (DUF1146) BF37_177 ENOG4105BZU Histidine kinase BF37_1770 ENOG4108IUW ABC transporter BF37_1771 ENOG4105DY9 regulatoR BF37_1774 ENOG4105FRN stage II sporulation protein BF37_1776 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BF37_1789 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF37_179 ENOG4105PXI polysaccharide deacetylase BF37_1792 ENOG4105CMR udp-glucose 4-epimerase BF37_1793 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_1794 ENOG4105BZU Histidine kinase BF37_1797 ENOG4105CXY transporter BF37_1801 ENOG4105C19 ABC transporter BF37_1802 ENOG4107RBB ABC transporter, permease BF37_1804 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_181 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BF37_1810 ENOG4105C0D helicase BF37_1811 ENOG4105KBK Zinc finger, swim domain protein BF37_1816 ENOG41069ER domain protein BF37_1817 ENOG4105C94 Transporter BF37_1819 ENOG4107R8N Glycosyl transferase, family 2 BF37_182 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BF37_1825 ENOG4105E0M Sulfatase BF37_1828 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BF37_1830 ENOG4105DAA L-lactate BF37_1838 ENOG4107RSM transcriptional regulator BF37_1839 ENOG4105ECB domain protein BF37_1840 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_1843 ENOG4105VZJ PTS System BF37_1845 ENOG4105VCP PTS System BF37_1846 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BF37_1847 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BF37_1849 ENOG4105CK1 PTS System BF37_1850 ENOG4105VCP PTS System BF37_1851 ENOG4105F8D glycoside hydrolase family 4 BF37_1852 ENOG410901P UPF0249 protein BF37_1855 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BF37_1857 ENOG4105ESV Glycosyl transferase, family 4 BF37_1858 ENOG4105C6Y Udp-glucose 6-dehydrogenase BF37_1859 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF37_1860 ENOG4108KGH TRANSCRIPTIONal BF37_1861 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BF37_1863 ENOG4105KVH Transcriptional regulator BF37_1866 ENOG41081UC Inherit from COG: Competence protein BF37_1867 ENOG4105VEQ Cold shock protein BF37_1868 ENOG4105MS2 ribosomal subunit Interface protein BF37_1869 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BF37_187 ENOG4105E98 transcriptional regulator DeoR family BF37_1870 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BF37_1872 ENOG4105CAK Cell division ATP-binding protein ftsE BF37_1873 ENOG4105CRP Part of the ABC transporter FtsEX involved in BF37_1874 ENOG4105CN1 protease BF37_1876 ENOG4105BZ1 (ABC) transporter BF37_1879 ENOG4108WS4 fmn reductase BF37_1881 ENOG4105DUM transcriptional regulator, lysR family BF37_1882 ENOG4105HMI Membrane BF37_1886 ENOG4107TXC Transcriptional regulator BF37_1889 ENOG4105D7V transposase BF37_1890 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BF37_1891 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF37_1893 ENOG41086DT Membrane protein of unknown function BF37_1897 ENOG4108S4C acetyltransferase BF37_1899 ENOG4105C3M thioredoxin reductase BF37_1901 ENOG4108Z4K mutator MutT protein BF37_1903 ENOG4105CHW UPF0052 protein BF37_1905 ENOG4105KRI phosphocarrier protein (HPr BF37_1906 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BF37_1907 ENOG4105H67 Protein of unknown function (DUF421) BF37_191 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BF37_1910 ENOG4105CZ3 stage V sporulation protein ad BF37_1911 ENOG41090VF Stage v sporulation protein ac BF37_1915 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_192 ENOG4107RCV ABC transporter, permease BF37_1920 ENOG4105CP7 Triose-phosphate isomerase BF37_1921 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BF37_1923 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF37_1928 ENOG4105EFC phage portal protein HK97 family BF37_1948 ENOG41067MG lrgb family BF37_1949 ENOG4105XZU Preprotein translocase, subunit SecG BF37_195 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF37_1951 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BF37_1956 ENOG4105CM4 permease protein BF37_1957 ENOG4108IPW abc transporter atp-binding protein BF37_1960 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BF37_1961 ENOG4108MK9 spermidine N(1)-acetyltransferase BF37_1964 ENOG4105WMR Protein CrcB homolog BF37_1965 ENOG4105WMR Protein CrcB homolog BF37_1967 ENOG4105C8Q Methyl-accepting chemotaxis BF37_1969 ENOG4105D4A Cell wall formation (By similarity) BF37_197 ENOG4105C4Y ABC transporter BF37_1970 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BF37_1973 ENOG4105KVH Transcriptional regulator BF37_1974 ENOG4105F27 Major Facilitator BF37_1975 ENOG4105CV8 reductase BF37_1980 ENOG4108RYK Nad-dependent epimerase dehydratase BF37_1983 ENOG4105D9N nucleoside BF37_1984 ENOG4105D9N nucleoside BF37_1989 ENOG4108URH decarboxylase BF37_1992 ENOG4108RMU ferritin dps family protein BF37_1994 ENOG4105NCW Trka-c domain protein BF37_1995 ENOG4107S91 Sodium hydrogen exchanger BF37_1999 ENOG4105D4Y metalloprotease BF37_2 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BF37_2000 ENOG4105VG1 fes assembly suf system protein BF37_2003 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BF37_2005 ENOG4105BZU Histidine kinase BF37_2006 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_2007 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BF37_2009 ENOG4107ZTW SNARE associated Golgi BF37_201 ENOG4105MWK D-amino acid dehydrogenase, small subunit BF37_2016 ENOG4107AYK membrAne BF37_2018 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF37_2020 ENOG4107R7I amino acid BF37_2021 ENOG4108SUT Major Facilitator Superfamily BF37_2025 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF37_2029 ENOG4105DZ1 carboxypeptidase BF37_203 ENOG4105CHR reductase BF37_2032 ENOG4105CHU acetyl-coa acetyltransferase BF37_2033 ENOG4105C1G acyl-Coa dehydrogenase BF37_2034 ENOG4108W8B Beta-lactamase domain protein BF37_2040 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF37_2049 ENOG41080E8 Transcriptional regulator, Spx MgsR family BF37_2055 ENOG4108UMI ABC transporter, permease BF37_2056 ENOG4105D01 (LipO)protein BF37_2057 ENOG4105D01 (LipO)protein BF37_2058 ENOG4105C3K feS assembly ATPase SufC BF37_2059 ENOG4105JRK feS assembly protein SufD BF37_2060 ENOG4105C9B Cysteine desulfurase BF37_2061 ENOG4108UNV SUF system FeS assembly protein, NifU family BF37_2062 ENOG4105DIW FeS assembly protein SUFB BF37_2065 ENOG4107R8B 5'-nucleotidase BF37_2066 ENOG4105KZD Domain of unknown function (DUF1805) BF37_2068 ENOG4105FAA peptidase M23 BF37_207 ENOG4108Z7G MaoC domain protein dehydratase BF37_2073 ENOG41090T1 Membrane BF37_2074 ENOG4107TXC Transcriptional regulator BF37_2075 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BF37_2076 ENOG4105MMD transcriptional regulator BF37_2079 ENOG4105CBT Fructose-1,6-bisphosphatase BF37_208 ENOG410681C small acid-soluble spore protein BF37_2082 ENOG4105D4U had-superfamily hydrolase, subfamily iia BF37_2083 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF37_2085 ENOG4108W5N phosphatidylglycerophosphatase a BF37_2088 ENOG41083MR nifu domain-containing protein BF37_209 ENOG4105CZN Potassium uptake protein BF37_2097 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BF37_2098 ENOG4105C4B ABC transporter, permease BF37_2099 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BF37_210 ENOG4107TS3 membrane protein, TerC BF37_2103 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BF37_2106 ENOG4105EWC Purine nucleoside phosphorylase BF37_211 ENOG4108QTI )-transporter BF37_2112 ENOG4105CEP NADH dehydrogenase BF37_2115 ENOG41069ER domain protein BF37_2119 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF37_2123 ENOG4105KA0 thioesterase Superfamily protein BF37_2124 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BF37_2127 ENOG4107R3E Citrate transporter BF37_2129 ENOG4105Y38 Kinase-associated protein B BF37_213 ENOG4106A3R peptidase BF37_2132 ENOG4105C87 Aminotransferase class I and II BF37_2134 ENOG4108MUZ hydrolase BF37_2135 ENOG4105C5I Dehydrogenase BF37_2136 ENOG4108ZB6 transcriptional regulator AsnC family BF37_2137 ENOG4105CHM Aminotransferase BF37_2139 ENOG4105WG9 Conserved Protein BF37_2140 ENOG4107QYV phosphohexose isomerase BF37_2141 ENOG4107PBV potassium channel BF37_2143 ENOG4105KT7 mgtC SapB transporter BF37_2151 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BF37_217 ENOG4105JXH GntR family transcriptional regulator BF37_2170 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF37_2172 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BF37_2174 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BF37_2179 ENOG4105VEQ Cold shock protein BF37_218 ENOG4105BZU Histidine kinase BF37_2181 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF37_2182 ENOG4105E4F Isochorismate synthase BF37_2183 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BF37_2184 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BF37_2185 ENOG4108IPT Naphthoate synthase BF37_2187 ENOG4105DTQ mandelate racemase muconate lactonizing BF37_219 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_2193 ENOG41069H0 dihydroorotase EC 3.5.2.3 BF37_2197 ENOG4105FDP GntR family transcriptional regulator BF37_2198 ENOG4105C6Z Gluconate BF37_22 ENOG4108S6Z Negative regulator of genetic competence BF37_2209 ENOG41086D8 Transcriptional regulator BF37_2210 ENOG4105C19 ABC transporter BF37_2213 ENOG4107ZTW SNARE associated Golgi BF37_222 ENOG4105CQB FAD linked oxidase domain protein BF37_2220 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BF37_2221 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF37_2226 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_2227 ENOG4105BZU Histidine kinase BF37_223 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BF37_2234 ENOG41087YS Phage shock protein A BF37_224 ENOG4105K4I Scp-like extracellular BF37_2243 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF37_2244 ENOG4105C4M (Ubiquinol oxidase) subunit I BF37_2246 ENOG4108V2W Carbonate dehydratase BF37_2253 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BF37_2257 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BF37_2259 ENOG4105D2X ABC transporter substrate-binding protein BF37_226 ENOG4108YBP pseudouridine synthase BF37_2263 ENOG4107T7U Sulfatase BF37_2264 ENOG4107S9D Alpha beta hydrolase BF37_2267 ENOG4105BZU Histidine kinase BF37_2268 ENOG4105EGD dinuclear metal center protein, YbgI family BF37_2278 ENOG4108RIR Molybdenum cofactor biosynthesis protein BF37_228 ENOG4105EYF MMPL domain protein BF37_2280 ENOG4105BZF Glycosyl transferase (Group 1 BF37_2281 ENOG4105YVM Phosphoesterase, PA-phosphatase related BF37_2282 ENOG4108Z0R Transferase BF37_2283 ENOG4105E8V Alpha Beta Hydrolase Fold protein BF37_2289 ENOG4105DA5 (ABC) transporter BF37_2291 ENOG4105N5T Radical SAM Protein BF37_2295 ENOG4105C19 ABC transporter BF37_2298 ENOG4105NCW Trka-c domain protein BF37_2299 ENOG4107S91 Sodium hydrogen exchanger BF37_23 ENOG4107X2D transcriptional regulator, merr family BF37_230 ENOG4107RUE extracellular solute-binding protein family 1 BF37_2300 ENOG410605W Major Facilitator BF37_2306 ENOG4108B31 Spore germination protein BF37_2308 ENOG4105DWV Homoserine O-trans-acetylase BF37_231 ENOG4105D38 putrescine abc transporter BF37_2310 ENOG41085GJ domain protein BF37_2314 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF37_2315 ENOG4105D06 uba thif-type nad fad binding protein BF37_2317 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF37_2318 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BF37_2319 ENOG4108ZAF Molybdopterin BF37_232 ENOG4105F38 ABC transporter, permease BF37_2322 ENOG4105CSC Glucose uptake protein BF37_2323 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BF37_2324 ENOG4108VJ1 Transcriptional regulator (CarD family BF37_233 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF37_2331 ENOG4105CBX hi0933 family BF37_2334 ENOG4105YW5 deoR family transcriptional regulator BF37_2335 ENOG4107QSE Dipeptidase BF37_2336 ENOG4107QSE Dipeptidase BF37_2338 ENOG4108IUM Glycogen debranching enzyme BF37_2339 ENOG4108V15 phosphotransferase enzyme family BF37_234 ENOG4105C26 Dehydrogenase BF37_2342 ENOG4105C8F Beta-lactamase domain protein BF37_2348 ENOG4108VDD TRNA binding domain protein BF37_2357 ENOG4105C88 aminopeptidase BF37_2361 ENOG4105ETE Transcriptional regulator (LacI family BF37_2367 ENOG4105EP9 oxidoreductase BF37_2368 ENOG4107SNB ankyrin repeat protein YahD BF37_2370 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_2372 ENOG4105DGU Histone deacetylase BF37_2373 ENOG4105W87 Cbs domain BF37_2374 ENOG4105F1V Acetoin utilization protein BF37_2377 ENOG4105EMN RNA polymerase sigma factor BF37_2379 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BF37_2383 ENOG4105C28 cystathionine BF37_2385 ENOG4105U5Y Transcriptional regulator BF37_2386 ENOG4105U5Y Transcriptional regulator BF37_2388 ENOG4106KR7 LysR family Transcriptional regulator BF37_2393 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF37_2395 ENOG4105EFZ amidohydrolase BF37_2398 ENOG4105KBJ sporulation protein ytfj BF37_2399 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BF37_24 ENOG4107RGJ metallophosphoesterase BF37_240 ENOG4105VFR signal peptidase BF37_2401 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BF37_2405 ENOG4108JYZ YitT family BF37_241 ENOG4105DZ1 carboxypeptidase BF37_2414 ENOG4107YZX Universal stress protein BF37_2418 ENOG4105VZ8 Transcriptional regulator BF37_2420 ENOG41082W1 Cupin 2, conserved barrel domain protein BF37_2421 ENOG4105Z7P Acetyltransferase (GNAT) family BF37_2428 ENOG4105DC7 peptidase M24 BF37_243 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BF37_2435 ENOG4105SFS phosphoesterase RecJ domain protein BF37_2437 ENOG4105VV2 BF37_2438 ENOG4105C0B DNA polymerase III (alpha subunit) BF37_2439 ENOG4105C6K Malic enzyme BF37_2440 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF37_2445 ENOG4105FS0 cytoplasmic membrane protein BF37_2446 ENOG4108REF Sporulation integral membrane protein ytvi BF37_2448 ENOG4105BZN citrate synthase BF37_2449 ENOG4108HMX isocitrate dehydrogenase (NADP) BF37_2453 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_2454 ENOG4105BZU Histidine kinase BF37_2455 ENOG4105C2M dna polymerase I BF37_2456 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BF37_2458 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BF37_2459 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BF37_2460 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BF37_2464 ENOG4108TDW sporulation protein YtxC BF37_2465 ENOG4105C22 threonyL-tRNA synthetase BF37_2466 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BF37_2470 ENOG4105CN9 Peptidase m42 family protein BF37_2471 ENOG4108JGH Tetr family transcriptional regulator BF37_2472 ENOG4105CW7 secretion protein, HlyD family BF37_2473 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_2480 ENOG4108RWN rrna methyltransferase BF37_2482 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BF37_2483 ENOG4105C5S asparaginyl-tRNA synthetase BF37_2490 ENOG4105DCG PHP domain protein BF37_2493 ENOG4105FE9 pseudouridine synthase BF37_2495 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BF37_2497 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BF37_2500 ENOG4105E0A ABC, transporter BF37_2501 ENOG4105KFN sortase, SrtB family BF37_2504 ENOG4105DR4 Methyltransferase BF37_2507 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_2516 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF37_2517 ENOG4105J76 Periplasmic binding protein BF37_2519 ENOG4105CEY Amp-dependent synthetase and ligase BF37_2520 ENOG4107Z3H Transcriptional regulator, TetR family BF37_2521 ENOG41060WC Enoyl-CoA hydratase BF37_2522 ENOG4105BZJ Electron transfer flavoprotein BF37_2523 ENOG4105C10 Electron transfer flavoprotein BF37_2524 ENOG4105K63 Thioredoxin BF37_2527 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BF37_2529 ENOG4105E33 succinate dehydrogenase BF37_2531 ENOG4108VXD carboxy-peptidase BF37_2532 ENOG4105E14 MotA TolQ exbB proton channel BF37_2533 ENOG4105ER2 Ompa motb domain protein BF37_2534 ENOG4105ER2 Ompa motb domain protein BF37_2535 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BF37_2536 ENOG4108IUX (ABC) transporter BF37_2537 ENOG4105RHA ABC transporter, permease BF37_2538 ENOG4108Z40 Transcriptional regulator BF37_2539 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BF37_254 ENOG4105VZ8 Transcriptional regulator BF37_2541 ENOG4108JCI Transcriptional regulator BF37_2542 ENOG41067S9 phage shock protein C, PspC BF37_2545 ENOG4105DY9 regulatoR BF37_2546 ENOG4108HRK Histidine kinase BF37_2547 ENOG4108JQ7 (ABC) transporter BF37_2550 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF37_2551 ENOG4105DEF Extracellular solute-binding protein, family 5 BF37_2552 ENOG4105DZC cytosine deaminase BF37_2553 ENOG4105DZC cytosine deaminase BF37_2556 ENOG4105PFC Transcriptional regulator BF37_2559 ENOG4105KBX Transcriptional regulator, TetR family BF37_256 ENOG4105C7S Dehydrogenase BF37_2561 ENOG4108PCX Major Facilitator BF37_2563 ENOG4108XJQ germination protein BF37_2565 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BF37_2566 ENOG4105M59 Phosphodiesterase, mj0936 family BF37_2570 ENOG4108QCI YvbH-like oligomerisation region BF37_2576 ENOG4108IUQ atp-dependent protease BF37_2580 ENOG4105K56 Transcriptional regulator BF37_2585 ENOG4105D52 delta-aminolevulinic acid dehydratase BF37_2587 ENOG41068KH stage VI sporulation protein D BF37_2589 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BF37_2590 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BF37_2594 ENOG4105DFF Rod shape-determining protein mreb BF37_2595 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BF37_2598 ENOG4107QMS site-determining protein BF37_26 ENOG4105I7S Abortive infection protein BF37_2601 ENOG4105C03 ribonuclease BF37_2603 ENOG4105X36 (ribosomal) protein BF37_2606 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BF37_2609 ENOG4105EWM Histidine kinase BF37_2613 ENOG4105CQC Prephenate dehydratase BF37_2614 ENOG4108RPX mosc domain containing protein BF37_2617 ENOG4108IYU L-aspartate oxidase BF37_2618 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BF37_2623 ENOG41082BM Transcriptional regulator, arsr family BF37_2624 ENOG4108IPJ Membrane BF37_2625 ENOG4108IPJ Membrane BF37_2627 ENOG4108HUF Transporter BF37_2630 ENOG41061AI Protein of unknown function (DUF2905) BF37_2633 ENOG4105VIE preprotein translocase, subunit YajC BF37_2635 ENOG4108QG2 Membrane BF37_2636 ENOG4105CKP Polysaccharide Biosynthesis Protein BF37_2638 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BF37_2639 ENOG41076HS cation diffusion facilitator family transporter BF37_2640 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BF37_2642 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF37_2645 ENOG4105CUT histidyl-tRNA synthetase BF37_2647 ENOG4105CUZ uba thif-type nad fad binding protein BF37_2648 ENOG4108VCI transcription factor, rsfa family BF37_2649 ENOG4105D1H recombination factor protein RarA BF37_2651 ENOG4105C3J Cysteine desulfurase BF37_2652 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BF37_2654 ENOG4105C7H Helicase, RecD TraA family BF37_2655 ENOG41060CR BF37_2658 ENOG4105C02 permease BF37_2660 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF37_2664 ENOG4105HHA aminodeoxychorismate lyase BF37_2665 ENOG4108VQJ O-methyltransferase BF37_2666 ENOG4105XYU peptidase (U32 family) BF37_2667 ENOG4105CFP Peptidase U32 BF37_2670 ENOG4107XRG penicillin-binding protein BF37_2676 ENOG4105C28 cystathionine BF37_2677 ENOG4108EKI Dehydrogenase BF37_2679 ENOG4108V5C ABC transporter BF37_2680 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF37_2688 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_2689 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_2691 ENOG4105MIR Phenylalanine 4-monooxygenase BF37_2692 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BF37_2699 ENOG4108MUZ hydrolase BF37_27 ENOG4105C9U ATP-dependent DNA helicase RecQ BF37_2701 ENOG4105G6Z alkaline phosphatase BF37_2704 ENOG4108TVJ Nitroreductase BF37_2709 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_2711 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BF37_2712 ENOG4105CQW ribosome biogenesis GTPase YqeH BF37_2714 ENOG410812S Rna-binding protein BF37_2716 ENOG4108WF2 Metal Dependent Phosphohydrolase BF37_2718 ENOG4105DXX methyltransferase BF37_2720 ENOG4105KQC Competence protein BF37_2721 ENOG4108UK2 deaminase BF37_2722 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF37_2724 ENOG4105TQK DNA polymerase iii, delta' subunit BF37_2729 ENOG4105KVH Transcriptional regulator BF37_2730 ENOG4105CSA Coproporphyrinogen iii oxidase BF37_2732 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BF37_2736 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BF37_2737 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BF37_2739 ENOG4105KTH gatB Yqey BF37_274 ENOG4105DDQ anthranilate synthase BF37_2740 ENOG41068P3 sporulation protein YqfC BF37_2742 ENOG4105C9A Phoh family BF37_2743 ENOG4105CTJ Metal Dependent Phosphohydrolase BF37_2745 ENOG4107YR5 Diacylglycerol kinase BF37_2746 ENOG4105KG3 cytidine deaminase BF37_2747 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BF37_275 ENOG4105CRQ synthase (Component I) BF37_2752 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BF37_2753 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_2756 ENOG4105EGD dinuclear metal center protein, YbgI family BF37_276 ENOG4105CK7 Sodium proline symporter BF37_2761 ENOG41069ZM Protein of unknown function (DUF2624) BF37_2762 ENOG4108JYZ YitT family BF37_2763 ENOG4105FDK ABC transporter BF37_2765 ENOG4105N80 Ferric uptake regulator, Fur family BF37_2770 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF37_2772 ENOG4107RF6 penicillin-binding protein BF37_2773 ENOG4105PWN phosphate abc transporter BF37_2774 ENOG4105C8U phosphate abc transporter BF37_2775 ENOG4105E2Z phosphate ABC transporter (Permease BF37_2776 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BF37_2777 ENOG4108UTW Plays a role in the regulation of phosphate uptake BF37_2780 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BF37_2782 ENOG4105DKQ ROK family BF37_2784 ENOG4105C5X domain protein BF37_2788 ENOG4105C28 cystathionine BF37_2789 ENOG4105C28 cystathionine BF37_2791 ENOG4105C3R Methionine synthase BF37_2792 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BF37_28 ENOG4105T7X BF37_281 ENOG4108WVJ 2'-5' rna ligase BF37_2816 ENOG4105C0D helicase BF37_2822 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF37_2823 ENOG4105CJ1 ABC, transporter BF37_2830 ENOG41080TC multidrug resistance protein BF37_2834 ENOG4105WZW rhodanese family BF37_2835 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BF37_2840 ENOG4107YBY Hydrolase BF37_2841 ENOG4105CBJ Metal-dependent enzyme BF37_2844 ENOG4105DC7 peptidase M24 BF37_2849 ENOG4105CD2 stage iii sporulation protein aa BF37_2850 ENOG4105KR5 Stage iii sporulation protein BF37_2851 ENOG4108CQH stage III sporulation protein AC BF37_2852 ENOG4105KQ4 Stage iii sporulation protein ad BF37_2854 ENOG410644B Stage III sporulation protein af BF37_2859 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF37_2860 ENOG4108ZSR alkaline shock protein BF37_2865 ENOG4105CTB Polyprenyl synthetase BF37_2867 ENOG4105DX0 Hemolysin A BF37_2869 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BF37_2870 ENOG4105S1Z Stage IV sporulation protein B BF37_2871 ENOG4107QQR Sporulation BF37_2874 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF37_2876 ENOG4108JUB Transcriptional regulator BF37_2878 ENOG4107RDP Dehydrogenase BF37_2882 ENOG4105CPP Dehydrogenase, E1 component BF37_2883 ENOG4105C7S Dehydrogenase BF37_2885 ENOG4105E09 nadh pyrophosphatase BF37_2886 ENOG4105G7B Protein of unknown function (DUF2992) BF37_2888 ENOG4108HW3 (ABC) transporter BF37_2889 ENOG4105E5Q amino acid AbC transporter BF37_2890 ENOG4105CDA abc transporter atp-binding protein BF37_2891 ENOG4108QEG Membrane BF37_2892 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BF37_2894 ENOG4105D9U N-acetyltransferase BF37_2895 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BF37_290 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BF37_2902 ENOG4105EJQ L-serine dehydratase BF37_2903 ENOG4105II7 pyrroline-5-carboxylate reductase BF37_2905 ENOG41069FQ Metallo-beta-lactamase superfamily BF37_2906 ENOG4108IXY short-chain dehydrogenase reductase BF37_2909 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BF37_2917 ENOG4105CGH 5'-nucleotidase BF37_2918 ENOG4105DFD Na H antiporter BF37_292 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BF37_2920 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF37_2922 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BF37_2923 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF37_2924 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF37_2925 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BF37_2929 ENOG4108R6K riboflavin synthase, subunit alpha BF37_293 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BF37_2930 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF37_2934 ENOG4108YM7 Gcn5-related n-acetyltransferase BF37_2935 ENOG4105ETE Transcriptional regulator (LacI family BF37_2937 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF37_2941 ENOG4105RHY Pfam:UPF0157 BF37_2943 ENOG4105CPC Aldo Keto reductase BF37_2947 ENOG4105MZ9 stage II sporulation protein m BF37_2948 ENOG4105I3K Ferric uptake regulator, Fur family BF37_2950 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF37_2955 ENOG4105D7N magnesium and cobalt transport protein CorA BF37_2962 ENOG4105DVE abc transporter atp-binding protein BF37_2963 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF37_2964 ENOG4105DZ1 carboxypeptidase BF37_2965 ENOG41082AN stage II sporulation protein BF37_2967 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_2968 ENOG4105C8J )-transporter BF37_297 ENOG4107TVC Glycosyl transferase, family 2 BF37_2972 ENOG41090VF Stage v sporulation protein ac BF37_2973 ENOG4105CZ3 stage V sporulation protein ad BF37_2975 ENOG4105G6R Stage v sporulation protein ae BF37_2977 ENOG4105J7I hydrolase BF37_2978 ENOG4105PTM secreted protein BF37_2979 ENOG4107ZE5 PPIases accelerate the folding of proteins BF37_2986 ENOG4105CE4 GlcNAc 6-P deacetylase BF37_2988 ENOG4105FDP GntR family transcriptional regulator BF37_2990 ENOG4105CID antiterminator BF37_2993 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BF37_2997 ENOG4106TD9 Diguanylate cyclase BF37_2998 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF37_2999 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF37_30 ENOG4108SAX Membrane BF37_3002 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BF37_3007 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BF37_3009 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BF37_301 ENOG4105K64 Glycosyl transferase, family 2 BF37_3011 ENOG4105DTD Dehydrogenase BF37_3012 ENOG4105K7K Transcriptional regulator BF37_3019 ENOG4105CHU acetyl-coa acetyltransferase BF37_3028 ENOG4105CG3 alpha amylase, catalytic region BF37_303 ENOG4105CNI cell division protein FtsW BF37_3030 ENOG4107FKK extracellular solute-binding protein family 1 BF37_3032 ENOG4105EG2 ABC transporter, permease BF37_3033 ENOG4105FKQ transcriptional regulator BF37_3034 ENOG4105CHM Aminotransferase BF37_3036 ENOG4108HGU Histidine kinase BF37_3047 ENOG4105UIN BF37_3049 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BF37_3052 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BF37_3053 ENOG4105EPM Diguanylate phosphodiesterase BF37_3056 ENOG4107IN1 Protein of unknown function (DUF1797) BF37_3058 ENOG4108XRC Protein of unknown function (DUF458) BF37_306 ENOG4105EMS pseudouridine synthase BF37_3065 ENOG4107ZYR domain protein BF37_3066 ENOG4105CN5 Metallo-Beta-Lactamase BF37_3068 ENOG4108X4Q Hydrolase BF37_3069 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF37_307 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BF37_3072 ENOG4105CPP Dehydrogenase, E1 component BF37_3073 ENOG4105C7S Dehydrogenase BF37_3082 ENOG4105CXN decarboxylase BF37_3086 ENOG4105ECY inositol monophosphatase BF37_3088 ENOG4105CI3 gtp-binding protein typa BF37_3089 ENOG4105QA2 BF37_3093 ENOG4108IAB Phoh family BF37_3096 ENOG4105CNI cell division protein FtsW BF37_3097 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BF37_310 ENOG4105MIX Adenylate cyclase BF37_3107 ENOG4106UY4 Inherit from COG: Scp-like extracellular BF37_311 ENOG4108Z18 K06886 hemoglobin BF37_3110 ENOG4107TB6 phosphoglycerate mutase BF37_3115 ENOG4106H78 methyltransferase BF37_3116 ENOG4105H20 Sporulation integral membrane protein YlbJ BF37_3118 ENOG4105D78 K07001 NTE family protein BF37_3119 ENOG41063PX domain protein BF37_3121 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BF37_3129 ENOG4108IMY Transcriptional regulator BF37_314 ENOG4105DPN Oligoendopeptidase f BF37_3140 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_3143 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BF37_316 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF37_3161 ENOG4105CAR Terminase, large subunit BF37_3163 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BF37_318 ENOG4108ZCF integral membrane protein BF37_3180 ENOG4105XSJ toxin secretion phage lysis holin BF37_3190 ENOG4105KNH Nucleic acid-binding protein BF37_3197 ENOG41068DC Essential cell division protein (By similarity) BF37_3198 ENOG4105CJN penicillin-binding protein BF37_3199 ENOG4105CJN penicillin-binding protein BF37_3200 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF37_3203 ENOG4105CNI cell division protein FtsW BF37_3204 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BF37_3205 ENOG4105D4A Cell wall formation (By similarity) BF37_3206 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BF37_3207 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BF37_3208 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BF37_3210 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_3212 ENOG4105WR5 sporulation protein, YlmC YmxH family BF37_3213 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BF37_3214 ENOG4105DFA alanine racemase domain protein BF37_3216 ENOG41067XK integral membrane protein BF37_3217 ENOG4105DBK s4 domain protein BF37_3219 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BF37_322 ENOG4105UQX Mate efflux family protein BF37_3222 ENOG4105C34 Pseudouridine synthase BF37_3227 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BF37_323 ENOG4108JQ7 (ABC) transporter BF37_3238 ENOG4105DC7 peptidase M24 BF37_3239 ENOG4105F23 Fibronectin-binding protein BF37_3241 ENOG4105DSJ YicC domain protein BF37_3245 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BF37_3246 ENOG4105C25 Primosomal protein n' BF37_3247 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF37_3249 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BF37_325 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF37_3251 ENOG4108ZF3 Phosphatase BF37_3252 ENOG4105D9P serine threonine protein kinase BF37_3253 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BF37_3254 ENOG4105DJV ribulose-phosphate 3-epimerase BF37_3255 ENOG4105FJ0 thiamine BF37_3257 ENOG4108ZAA Alkaline-shock protein BF37_3258 ENOG4105DP4 dak2 domain fusion protein ylov BF37_3259 ENOG4105CB5 ATP-dependent DNA helicase recG BF37_326 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF37_3262 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BF37_3263 ENOG4105CHR reductase BF37_3266 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BF37_3267 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BF37_3271 ENOG4105VB6 UPF0109 protein BF37_3276 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BF37_3279 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BF37_3281 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF37_3283 ENOG4108HE4 integrase family BF37_329 ENOG4105C31 Tryptophanyl-tRNA synthetase BF37_3291 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BF37_3292 ENOG4105KNE Phosphatidate cytidylyltransferase BF37_3293 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BF37_3294 ENOG4105DZP Membrane-associated zinc metalloprotease BF37_3296 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF37_3298 ENOG4105CHV Transcription elongation factor NusA BF37_3299 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BF37_33 ENOG4108WBT adenosyltransferase BF37_3300 ENOG4105VHM ribosomal protein BF37_3302 ENOG4105W7A Protein of unknown function (DUF503) BF37_3304 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BF37_3305 ENOG4105DTN riboflavin biosynthesis protein ribF BF37_3309 ENOG4105C1V Peptidase, M16 BF37_3311 ENOG4105E35 Dipicolinate synthase subunit A BF37_3312 ENOG4108S0H Dipicolinic acid synthetase, b subunit BF37_3313 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF37_3315 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF37_3317 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BF37_3319 ENOG4107QZI cell division protein FtsK BF37_332 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF37_3320 ENOG4105FDP GntR family transcriptional regulator BF37_3321 ENOG4105DIH basic membrane BF37_3322 ENOG4108JQ9 ABC transporter BF37_3323 ENOG4105UIB (ABC) transporter BF37_3324 ENOG4105UIB (ABC) transporter BF37_3328 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BF37_3329 ENOG4105XZV Protein of unknown function (DUF3243) BF37_333 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF37_3332 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BF37_3337 ENOG4105D48 metallophosphoesterase BF37_3338 ENOG4105MCT stage V sporulation protein S BF37_3339 ENOG4108IGT Dipeptidase BF37_3340 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BF37_3341 ENOG4105DQU oxidoreductase, subunit beta BF37_3342 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BF37_3347 ENOG4105DA5 (ABC) transporter BF37_3352 ENOG4107QHE Choloylglycine hydrolase BF37_3354 ENOG410890F Dynamin family BF37_3355 ENOG4105E0M Sulfatase BF37_3356 ENOG4107R6R udp-galactopyranose mutase BF37_3357 ENOG4105F0V Cell wall hydrolase BF37_3361 ENOG4107YEI lmbE family BF37_3362 ENOG4107TTQ Alpha beta hydrolase fold BF37_3369 ENOG4105BZU Histidine kinase BF37_3370 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_3376 ENOG4105D03 DNA-3-methyladenine glycosylase II BF37_338 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF37_3380 ENOG4105CGK Exodeoxyribonuclease III BF37_3385 ENOG4105E0A ABC, transporter BF37_3386 ENOG4105NIV Esterase BF37_3388 ENOG4105VPX protein, conserved in bacteria BF37_3389 ENOG410681U heavy metal transport detoxification protein BF37_3390 ENOG4105C59 p-type ATPase BF37_3391 ENOG4105C59 p-type ATPase BF37_3392 ENOG4105K70 DNA-binding protein BF37_3393 ENOG4105TMB Formate nitrite transporter BF37_3397 ENOG4105C85 amino acid BF37_34 ENOG4105BZU Histidine kinase BF37_340 ENOG4108KP7 hydrolase BF37_3400 ENOG4108SJC Membrane BF37_3401 ENOG4107QW4 alcohol dehydrogenase BF37_3402 ENOG4107QW4 alcohol dehydrogenase BF37_3403 ENOG4105E98 transcriptional regulator DeoR family BF37_3404 ENOG4105DE4 1-phosphofructokinase BF37_3405 ENOG4105DM4 PTS System BF37_3406 ENOG41069ER domain protein BF37_3413 ENOG4106F1P AAA ATPase, central domain protein BF37_3414 ENOG4105EN6 Membrane BF37_3415 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF37_3416 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF37_3417 ENOG4105CXI aluminum resistance protein BF37_3418 ENOG4105KV4 Transcriptional regulator BF37_3419 ENOG4105C5F glutamine synthetase BF37_342 ENOG41073B9 BF37_343 ENOG4107AYK membrAne BF37_3441 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BF37_345 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF37_347 ENOG4105QNR S1 RNA binding domain protein BF37_3481 ENOG4105XSJ toxin secretion phage lysis holin BF37_3482 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BF37_3490 ENOG4105K7K Transcriptional regulator BF37_3494 ENOG4108SVB resolvase BF37_3496 ENOG4105CGH 5'-nucleotidase BF37_3499 ENOG4105D5T phosphonate abc transporter BF37_35 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_3502 ENOG4105D7V transposase BF37_3506 ENOG4105BZ1 (ABC) transporter BF37_3507 ENOG4105BZ1 (ABC) transporter BF37_3510 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF37_3515 ENOG41067MG lrgb family BF37_3516 ENOG4105VAW lrga family BF37_3517 ENOG4107RSM transcriptional regulator BF37_3519 ENOG4107QIV Cytochrome c biogenesis protein BF37_352 ENOG4105BZU Histidine kinase BF37_353 ENOG4105CH6 catalase BF37_3530 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BF37_3535 ENOG4108903 Formimidoylglutamase BF37_3536 ENOG4108VJ1 Transcriptional regulator (CarD family BF37_3537 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BF37_3538 ENOG4105CBC glutamate synthase BF37_3539 ENOG4105CK7 Sodium proline symporter BF37_354 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BF37_3540 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BF37_3541 ENOG4105FBA Phospholipase Carboxylesterase BF37_3542 ENOG4105BZU Histidine kinase BF37_3544 ENOG4107AYK membrAne BF37_355 ENOG4105CAQ asparagine synthetase BF37_3553 ENOG4105CEY Amp-dependent synthetase and ligase BF37_3554 ENOG4107ZYJ bioY protein BF37_3555 ENOG4107F3J Amp-dependent synthetase and ligase BF37_3559 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF37_3561 ENOG4105E5W Transporter BF37_3566 ENOG4108I0Z Aconitate hydratase BF37_3567 ENOG4108JJA ABC, transporter BF37_3569 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF37_3570 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF37_3576 ENOG4105W8X HesB YadR YfhF-family protein BF37_3577 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BF37_3578 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BF37_3580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_3581 ENOG4105C0H protease BF37_3582 ENOG4105K4P CoA-binding domain protein BF37_3583 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF37_3585 ENOG4105D9R oxidoreductase BF37_3587 ENOG4105CIG ABC transporter BF37_3591 ENOG4105EMN RNA polymerase sigma factor BF37_3593 ENOG4108KGH TRANSCRIPTIONal BF37_3594 ENOG4107QJT sodium dicarboxylate symporter BF37_36 ENOG4105CRE cytochrome C BF37_360 ENOG4105ERH Fumarylacetoacetate hydrolase BF37_3607 ENOG4105E1K spore germination protein BF37_3609 ENOG4108JB9 formate dehydrogenase BF37_3611 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BF37_3612 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF37_3614 ENOG4105TMB Formate nitrite transporter BF37_3615 ENOG4105D06 uba thif-type nad fad binding protein BF37_3616 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF37_3617 ENOG4108ZAF Molybdopterin BF37_3619 ENOG4105D1F ATP-binding protein BF37_3622 ENOG410696E Membrane BF37_3623 ENOG4105FR1 rard protein BF37_3625 ENOG4105EWU Squalene--hopene cyclase BF37_3627 ENOG4105CHR reductase BF37_3628 ENOG4105C26 Dehydrogenase BF37_3629 ENOG4105RG0 Membrane BF37_3630 ENOG4108IA2 Sodium pantothenate symporter BF37_3633 ENOG4106IQC argininosuccinate lyase BF37_3636 ENOG410904N short-chain dehydrogenase reductase BF37_3640 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BF37_3644 ENOG4105VEQ Cold shock protein BF37_3648 ENOG4108R1P BF37_3650 ENOG41073R8 VanW family BF37_3651 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_3653 ENOG4105KT7 mgtC SapB transporter BF37_3655 ENOG4105E39 Enoyl-CoA hydratase BF37_3656 ENOG4105K64 Glycosyl transferase, family 2 BF37_3658 ENOG4108UT6 Transferase hexapeptide repeat containing protein BF37_3662 ENOG4105CQB FAD linked oxidase domain protein BF37_3663 ENOG4105C09 Bile acid BF37_3665 ENOG4105RHY Pfam:UPF0157 BF37_3671 ENOG4105CIS alcohol dehydrogenase BF37_3672 ENOG41082BM Transcriptional regulator, arsr family BF37_3676 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF37_368 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BF37_3682 ENOG4108A04 Beta-lactamase BF37_3683 ENOG4105DPN Oligoendopeptidase f BF37_3684 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BF37_3685 ENOG4105E5K Alpha-amylase BF37_3687 ENOG4105C98 muts2 protein BF37_369 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BF37_3691 ENOG4107V2S Transcriptional regulator BF37_3693 ENOG4107CUJ Protein of unknown function (DUF2690) BF37_3697 ENOG4107ZY0 Phenazine biosynthesis-like protein BF37_3698 ENOG4105NX3 Membrane BF37_3699 ENOG4105DQ5 transport system permease protein BF37_37 ENOG4107TWT Cytochrome c biogenesis protein BF37_3700 ENOG4105EHG Permease protein BF37_3702 ENOG4108MES Periplasmic binding protein BF37_3706 ENOG4107R3E Citrate transporter BF37_3708 ENOG4108TN2 lmbE family BF37_3715 ENOG4105CIS alcohol dehydrogenase BF37_372 ENOG4105XVF Competence transcription factor BF37_3722 ENOG4105H3G oxidoreductase BF37_3724 ENOG4105ED2 Beta-lactamase BF37_3729 ENOG4107YXZ hydrolase, family 25 BF37_3733 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BF37_3738 ENOG4105KAF membrAne BF37_3748 ENOG4108ZJ4 polysaccharide deacetylase BF37_375 ENOG4105VEQ Cold shock protein BF37_3752 ENOG4105KVH Transcriptional regulator BF37_3753 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BF37_3757 ENOG4105CHR reductase BF37_3759 ENOG4105JAB phenazine biosynthesis protein, phzf family BF37_3766 ENOG4105KVH Transcriptional regulator BF37_3767 ENOG4105KVH Transcriptional regulator BF37_3768 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BF37_3770 ENOG4105D9R oxidoreductase BF37_3771 ENOG4108TZY GntR Family Transcriptional Regulator BF37_3772 ENOG4105KVH Transcriptional regulator BF37_3779 ENOG4105C44 Serine transporter BF37_378 ENOG4107QP3 malate synthase g BF37_3780 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BF37_3783 ENOG4105F27 Major Facilitator BF37_3784 ENOG4105CV8 reductase BF37_3788 ENOG4105D4Y metalloprotease BF37_3789 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BF37_379 ENOG4105ZU5 s-layer protein BF37_3792 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BF37_3793 ENOG4105CIS alcohol dehydrogenase BF37_3794 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF37_3795 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF37_3798 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF37_3799 ENOG4105C6Z Gluconate BF37_3800 ENOG4105CMG Carbohydrate kinase BF37_3801 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BF37_3802 ENOG4105XDF Protein of unknown function (DUF1272) BF37_3803 ENOG4105DDN Pentapeptide repeat-containing protein BF37_3806 ENOG4105C37 (CBS) domain BF37_3812 ENOG4105EV4 Multidrug resistance protein mdtH BF37_3814 ENOG4105DMQ Methyltransferase BF37_3819 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BF37_3820 ENOG4105C31 Tryptophanyl-tRNA synthetase BF37_3822 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BF37_3824 ENOG4108UW5 maltose o-acetyltransferase BF37_3825 ENOG4106UW1 Major Facilitator superfamily BF37_3826 ENOG4105DKQ ROK family BF37_3827 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_3839 ENOG4105CJ1 ABC, transporter BF37_3841 ENOG4108PSK reductase BF37_3845 ENOG4108RCM Nitroreductase BF37_3846 ENOG4105KVH Transcriptional regulator BF37_3849 ENOG4105CUT histidyl-tRNA synthetase BF37_385 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BF37_3850 ENOG4108Z66 YbaK ebsC protein BF37_3852 ENOG41067QW Transcriptional regulator BF37_3855 ENOG4108K8S endonuclease I BF37_3860 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF37_3861 ENOG4108JJB ABC transporter BF37_3867 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF37_3869 ENOG4105CRW Short chain fatty acid transporter BF37_3871 ENOG4105KBX Transcriptional regulator, TetR family BF37_3872 ENOG4105KPY Small multidrug resistance protein BF37_3873 ENOG4105RXJ BF37_3875 ENOG41069JR BF37_3876 ENOG4105DA5 (ABC) transporter BF37_3880 ENOG4105CZM Major Facilitator BF37_3881 ENOG4107MII Sugar-specific transcriptional regulator TrmB BF37_3883 ENOG4108ISG Major Facilitator BF37_3891 ENOG4105HIR S-layer domain protein BF37_3894 ENOG410874W AraC family transcriptional regulator BF37_3895 ENOG41082W1 Cupin 2, conserved barrel domain protein BF37_3898 ENOG4108AEY RNA polymerase sigma factor BF37_39 ENOG4105FE9 pseudouridine synthase BF37_390 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_3902 ENOG4108JQ1 Dehydrogenase BF37_3905 ENOG4105DVH amino acid BF37_3907 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BF37_3910 ENOG4108JPW Aminotransferase BF37_3912 ENOG4105EJQ L-serine dehydratase BF37_3913 ENOG4105C44 Serine transporter BF37_3916 ENOG4108JGH Tetr family transcriptional regulator BF37_3917 ENOG4105EQ0 Major Facilitator superfamily BF37_3918 ENOG4105MZU cell filamentation protein BF37_3921 ENOG4107QJQ Mate efflux family protein BF37_3928 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF37_3936 ENOG4105TRI Hydrolase BF37_394 ENOG41086D8 Transcriptional regulator BF37_3942 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF37_3944 ENOG4106P55 Transcriptional regulator BF37_3946 ENOG4107QR9 Iron-sulfur cluster binding protein BF37_3947 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BF37_3948 ENOG4105DJB Major Facilitator Superfamily BF37_3949 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF37_395 ENOG4108AEY RNA polymerase sigma factor BF37_3951 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BF37_3952 ENOG4108U05 Transcriptional regulator BF37_3955 ENOG4105BZU Histidine kinase BF37_3958 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BF37_3959 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BF37_3962 ENOG4105JQZ Methyltransferase BF37_3963 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF37_3965 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF37_3966 ENOG4108NNI Beta-lactamase domain-containing protein BF37_3969 ENOG4105VZ8 Transcriptional regulator BF37_397 ENOG4107TVP HD domain protein BF37_3975 ENOG4105K6H D-cysteine desulfhydrase BF37_398 ENOG4107RN3 metallophosphoesterase BF37_3980 ENOG41062D9 Histidine kinase BF37_3981 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_3984 ENOG4105IIP Membrane BF37_3986 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_3987 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BF37_400 ENOG4105ENX hydrolase BF37_4001 ENOG4108YXU transcriptional regulator AsnC family BF37_4002 ENOG4105CHR reductase BF37_4004 ENOG4105F7F Chaperone BF37_4009 ENOG41085FC arsR family transcriptional regulator BF37_4010 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_4011 ENOG4105D6J arsenicaL-resistance protein BF37_4017 ENOG4105DIK (ABC) transporter BF37_4018 ENOG4105CC5 ABC transporter BF37_4019 ENOG4105DSE periplasmic solute binding protein BF37_4020 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BF37_4021 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF37_4023 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BF37_4024 ENOG4108TWJ NADH dehydrogenase subunit 5 BF37_4027 ENOG4105CVP deoxyribo-dipyrimidine photolyase BF37_4028 ENOG4108606 TspO/MBR family BF37_4036 ENOG41090MY MarR family Transcriptional regulator BF37_4042 ENOG4105CHJ isochorismatase hydrolase BF37_4044 ENOG4105CH6 catalase BF37_4045 ENOG4105CGH 5'-nucleotidase BF37_405 ENOG4105CNA YD repeat protein BF37_4053 ENOG4105CSV Glutaminase BF37_4058 ENOG4108Q8B Spore germination protein BF37_4059 ENOG4108NHD germination protein BF37_4060 ENOG4108NHD germination protein BF37_4063 ENOG4105C6K Malic enzyme BF37_4065 ENOG4105II7 pyrroline-5-carboxylate reductase BF37_4067 ENOG4105CUB amino acid BF37_4068 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BF37_4070 ENOG4108IMY Transcriptional regulator BF37_4071 ENOG4105HDK L-asparaginase BF37_4072 ENOG4108IJ0 Aspartate ammonia-lyase BF37_4075 ENOG4105E2A Dehydrogenase BF37_4090 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BF37_4096 ENOG4105DWD nucleoside recognition domain protein BF37_41 ENOG4108JIC nucleoside recognition domain protein BF37_4100 ENOG4105FDT acyl-CoA dehydrogenase BF37_4102 ENOG4108ZHR arsR family transcriptional regulator BF37_4103 ENOG4108ZRV stage ii sporulation protein p BF37_4104 ENOG4106N3A copper homeostasis protein cutc BF37_4106 ENOG4107258 Transcriptional regulator BF37_4107 ENOG4105P4J Allophanate hydrolase, subunit 1 BF37_411 ENOG4105CEY Amp-dependent synthetase and ligase BF37_4114 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BF37_4116 ENOG4107RF6 penicillin-binding protein BF37_4124 ENOG4105F1N DNA alkylation repair BF37_4126 ENOG4108IQI permease BF37_4127 ENOG4105KNA -acetyltransferase BF37_4128 ENOG410635A Membrane BF37_413 ENOG4105DF9 Lipoate-protein, ligase BF37_414 ENOG4108RQ5 Beta-lactamase domain-containing protein BF37_4144 ENOG4108XET gCN5-related N-acetyltransferase BF37_415 ENOG4106AXD BF37_4150 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF37_4152 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF37_4159 ENOG4105FS7 Transcriptional regulator BF37_4160 ENOG4108TVJ Nitroreductase BF37_4162 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF37_4171 ENOG4105C8Y Acetylornithine aminotransferase BF37_4173 ENOG4105CKK Glycosyl transferase, family 2 BF37_4178 ENOG4105CKK Glycosyl transferase, family 2 BF37_4183 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF37_4188 ENOG41068WN BF37_4190 ENOG4108WCX response regulator BF37_4192 ENOG41090T1 Membrane BF37_4195 ENOG4105VMP Transcriptional regulator BF37_4197 ENOG4105G6Z alkaline phosphatase BF37_4198 ENOG4105ECK Fatty Acid Desaturase BF37_4199 ENOG4105E0Y RtcB Protein BF37_42 ENOG4105DZ1 carboxypeptidase BF37_4201 ENOG4107258 Transcriptional regulator BF37_4203 ENOG4105II7 pyrroline-5-carboxylate reductase BF37_4204 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BF37_421 ENOG4105ECB domain protein BF37_4210 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BF37_4214 ENOG41061GT Aldolase BF37_4217 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BF37_4218 ENOG4105DKT Transcriptional regulator BF37_4220 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BF37_4222 ENOG4105D4B ABC, transporter BF37_4228 ENOG4105EMN RNA polymerase sigma factor BF37_4230 ENOG41069ER domain protein BF37_4238 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BF37_4239 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BF37_424 ENOG4105NA0 Transcriptional regulator BF37_4240 ENOG4105CIH Imidazole acetol-phosphate transaminase BF37_4244 ENOG41082JN Transcriptional regulator BF37_4245 ENOG4105EYF MMPL domain protein BF37_4246 ENOG4105EYF MMPL domain protein BF37_4248 ENOG4105C5H ABC transporter BF37_4249 ENOG4105E0M Sulfatase BF37_4250 ENOG4108ZCF integral membrane protein BF37_4252 ENOG4107VMI polysaccharide deacetylase BF37_4254 ENOG4107VC0 DNA alkylation repair enzyme BF37_4264 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BF37_4268 ENOG4105E09 nadh pyrophosphatase BF37_4273 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BF37_4274 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BF37_4275 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BF37_4277 ENOG4105C02 permease BF37_4286 ENOG4105DVE abc transporter atp-binding protein BF37_429 ENOG4105C1Q protoporphyrinogen oxidase BF37_4292 ENOG4105CHM Aminotransferase BF37_4299 ENOG41089UC methyltransferase, type 11 BF37_43 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF37_4302 ENOG4107BMA Transglycosylase associated protein BF37_4306 ENOG4106K7D Major facilitator family transporter BF37_4307 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF37_431 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BF37_4315 ENOG4105EPR degv family BF37_4318 ENOG4105DPN Oligoendopeptidase f BF37_432 ENOG4105BZ4 penicillin-binding protein BF37_4325 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_4326 ENOG4105BZU Histidine kinase BF37_4327 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BF37_433 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BF37_4335 ENOG4105DTQ mandelate racemase muconate lactonizing BF37_4338 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BF37_4339 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF37_434 ENOG4105CKV Membrane BF37_4342 ENOG4107T5V SNARE associated Golgi BF37_4349 ENOG41080HI glycine oxidase BF37_435 ENOG410905X membrane-flanked domain protein BF37_4350 ENOG4105CTU Proline racemase BF37_4351 ENOG4105CTU Proline racemase BF37_4352 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF37_4353 ENOG4105C26 Dehydrogenase BF37_4354 ENOG4105BZG amino acid carrier protein BF37_4357 ENOG4108M1A Chitin-binding protein BF37_4365 ENOG4105C9U ATP-dependent DNA helicase RecQ BF37_4369 ENOG4105EEM helicase BF37_4373 ENOG4108Z7F N-acetyltransferase BF37_4379 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF37_4388 ENOG4108M1A Chitin-binding protein BF37_4389 ENOG41082BV acetyltransferase BF37_4390 ENOG4105E66 phosphoriboisomerase A BF37_4395 ENOG4108IJ7 Glycine betaine BF37_4396 ENOG4107SQ8 Glycine betaine BF37_4402 ENOG4105RHY Pfam:UPF0157 BF37_4403 ENOG4105E1F short-chain dehydrogenase reductase BF37_4405 ENOG4107RUY (E1 component), alpha subunit BF37_4407 ENOG4107QKR Dehydrogenase BF37_4412 ENOG41062ES Transcriptional regulator BF37_4416 ENOG4105E98 transcriptional regulator DeoR family BF37_4420 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BF37_4426 ENOG4107Z3H Transcriptional regulator, TetR family BF37_4427 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BF37_4428 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BF37_4429 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BF37_4433 ENOG4105MSI germination protein ypeb BF37_4437 ENOG4108V3A UPF0421 protein BF37_444 ENOG4105CKV Membrane BF37_4444 ENOG4105FDR Membrane BF37_4446 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF37_4455 ENOG4105DY8 decarboxylase BF37_446 ENOG410905X membrane-flanked domain protein BF37_4460 ENOG4105PAD Hydrolase BF37_4465 ENOG4107VFR oxidoreductase BF37_4473 ENOG4105PKS Excinuclease abc c subunit domain protein BF37_4480 ENOG4105KWG Pfam:DUF1696 BF37_4481 ENOG4108NRW Phospholipase, patatin family BF37_4487 ENOG4108XI2 Domain of unknown function (DUF1963) BF37_4494 ENOG4108Z4K mutator MutT protein BF37_4495 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF37_4496 ENOG4105E09 nadh pyrophosphatase BF37_4498 ENOG4105FCD Major Facilitator BF37_4505 ENOG4107Y9U Membrane BF37_4510 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF37_4514 ENOG4107Y80 Major Facilitator superfamily BF37_4519 ENOG4108V4B ThiJ pfpI BF37_4525 ENOG4105FQP Beta-lactamase BF37_4527 ENOG4105CJN penicillin-binding protein BF37_453 ENOG4105K59 histidine triad (HIT) protein BF37_4532 ENOG4108HGU Histidine kinase BF37_4535 ENOG4108JJB ABC transporter BF37_4539 ENOG4107RF6 penicillin-binding protein BF37_4540 ENOG4105BZU Histidine kinase BF37_4542 ENOG410667J hydrolase BF37_4566 ENOG4105ETU transcriptional activator (TenA BF37_458 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF37_4587 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF37_4588 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF37_459 ENOG4105EEM helicase BF37_4591 ENOG4105CPQ Dehydrogenase BF37_4597 ENOG4105CUV Homoserine Kinase BF37_4601 ENOG4107Y80 Major Facilitator superfamily BF37_4603 ENOG4105FQP Beta-lactamase BF37_4606 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF37_4606 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF37_461 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_4615 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BF37_4617 ENOG4105T9C HD domain BF37_462 ENOG4105C57 major facilitator superfamily BF37_4620 ENOG4105DZ1 carboxypeptidase BF37_4623 ENOG4105DBI uridine monophosphokinase BF37_4624 ENOG4105WCN acetyltransferase BF37_4626 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF37_4627 ENOG4107QX3 carboxylase BF37_4628 ENOG4105E39 Enoyl-CoA hydratase BF37_4629 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BF37_4630 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BF37_4631 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF37_4632 ENOG4105C1G acyl-Coa dehydrogenase BF37_4637 ENOG4105CJ1 ABC, transporter BF37_4640 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BF37_4641 ENOG4105CEP NADH dehydrogenase BF37_4642 ENOG4106ANW SMI1_KNR4 BF37_4644 ENOG4105BZU Histidine kinase BF37_4646 ENOG4105C5H ABC transporter BF37_4647 ENOG41067SE Tetr family transcriptional regulator BF37_4652 ENOG4108VXD carboxy-peptidase BF37_4655 ENOG4105VZ8 Transcriptional regulator BF37_4658 ENOG4105CGH 5'-nucleotidase BF37_4659 ENOG4105CGH 5'-nucleotidase BF37_4663 ENOG4105DH8 myo-inositol catabolism BF37_4664 ENOG4105D2N Aldolase BF37_4669 ENOG4105CK5 oxidoreductase BF37_467 ENOG4105EMN RNA polymerase sigma factor BF37_4670 ENOG4105IE8 Alpha-ketoglutarate permease BF37_4671 ENOG4105ETE Transcriptional regulator (LacI family BF37_4672 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF37_4674 ENOG4107RF6 penicillin-binding protein BF37_4675 ENOG4107RF6 penicillin-binding protein BF37_4676 ENOG4107RF6 penicillin-binding protein BF37_4682 ENOG4105CIN aminoacyl-histidine dipeptidase BF37_4688 ENOG41090HR transcriptional regulator BF37_4689 ENOG4107RA9 decarboxylase BF37_4690 ENOG4108I0C methyltransferase BF37_4692 ENOG41088CC tellurite resistance protein tehB BF37_4696 ENOG4108RZE Tetr family transcriptional regulator BF37_4698 ENOG4105C1J atp-dependent rna helicase BF37_470 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BF37_4701 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF37_4704 ENOG4107STF Involved in phosphonate degradation (By similarity) BF37_4706 ENOG4105RD7 BadF BadG BcrA BcrD BF37_4711 ENOG4105F32 YngK protein BF37_4716 ENOG4108KPJ rna polymerase sigma factor BF37_4721 ENOG4108JCI Transcriptional regulator BF37_4725 ENOG4105BZ1 (ABC) transporter BF37_4726 ENOG4105BZ1 (ABC) transporter BF37_4729 ENOG4108RPX mosc domain containing protein BF37_473 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF37_4730 ENOG4105DND Transcriptional regulator BF37_4733 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF37_4734 ENOG4107V2S Transcriptional regulator BF37_4742 ENOG410667J hydrolase BF37_4746 ENOG4105VEQ Cold shock protein BF37_4748 ENOG41068WN BF37_4750 ENOG4105C1Q protoporphyrinogen oxidase BF37_4756 ENOG4105WCN acetyltransferase BF37_4761 ENOG4105EYF MMPL domain protein BF37_4763 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF37_4766 ENOG41081I9 integral membrane protein BF37_477 ENOG4108MUZ hydrolase BF37_4772 ENOG4108D32 Methyltransferase BF37_4778 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF37_4782 ENOG4105C22 threonyL-tRNA synthetase BF37_4783 ENOG4105FE9 pseudouridine synthase BF37_4787 ENOG4105BZG amino acid carrier protein BF37_4791 ENOG4105K70 DNA-binding protein BF37_4794 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_4795 ENOG4105WQT MbtH domain protein BF37_4796 ENOG4105CEY Amp-dependent synthetase and ligase BF37_4797 ENOG4105WQI isochorismatase BF37_4798 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BF37_4799 ENOG4105E4F Isochorismate synthase BF37_4800 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BF37_4801 ENOG4105FCD Major Facilitator BF37_4805 ENOG4105EYH Exonuclease BF37_4806 ENOG4107RFY SbcCD D subunit BF37_4809 ENOG4105E39 Enoyl-CoA hydratase BF37_4810 ENOG4105N14 lysine exporter protein LysE YggA BF37_4812 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF37_4813 ENOG4105C1G acyl-Coa dehydrogenase BF37_4814 ENOG4105CR4 methylisocitrate lyase BF37_4815 ENOG4105DXD 2-methylcitrate dehydratase BF37_4817 ENOG4105W8X HesB YadR YfhF-family protein BF37_4818 ENOG4105CZM Major Facilitator BF37_4819 ENOG4105BZ4 penicillin-binding protein BF37_482 ENOG4105EQ0 Major Facilitator superfamily BF37_4827 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF37_483 ENOG4108IND Tetr family transcriptional regulator BF37_4846 ENOG4108IBT Inherit from COG: transposase BF37_4848 ENOG4105SZ6 Thioredoxin BF37_4849 ENOG410841Q phosphoesterase PA-phosphatase related protein BF37_4851 ENOG4108N23 SpoOM-related protein BF37_4859 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BF37_486 ENOG4105D7V transposase BF37_4860 ENOG4108JUB Transcriptional regulator BF37_4861 ENOG4108TSC N-acetyltransferase BF37_4862 ENOG4107S4Y M20 DapE family protein YgeY BF37_4865 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF37_487 ENOG4106D4I domain protein BF37_4870 ENOG4105C37 (CBS) domain BF37_4877 ENOG4105E90 ABC transporter BF37_4878 ENOG4108IJ8 ABC transporter BF37_488 ENOG4107VRP DNA repair exonuclease BF37_4884 ENOG4105CMG Carbohydrate kinase BF37_4885 ENOG4105CMG Carbohydrate kinase BF37_4894 ENOG4106KNT transcriptional regulator BF37_4896 ENOG4105WH1 Two component transcriptional regulator luxr family BF37_4897 ENOG4105BZU Histidine kinase BF37_4898 ENOG4105D8X mechanosensitive ion channel BF37_4905 ENOG4105F0I Aminotransferase BF37_4906 ENOG4108MES Periplasmic binding protein BF37_4910 ENOG4105CAQ asparagine synthetase BF37_4911 ENOG4107Y70 Heat shock protein BF37_4912 ENOG4108KF3 Electron transport protein SCO1 SenC BF37_4913 ENOG4105E8R UPF0173 metal-dependent hydrolase BF37_4914 ENOG4108RCR degv family BF37_4916 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BF37_4918 ENOG4108UT2 hemolysin iii BF37_4919 ENOG4105E9Q Acyl-transferase BF37_4920 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BF37_4921 ENOG4107RVG penicillin-binding protein BF37_4924 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BF37_4928 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BF37_4933 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BF37_4935 ENOG4105KD7 acetyltransferase BF37_4938 ENOG4105C0A alcohol dehydrogenase BF37_4939 ENOG4105CY2 Citrate transporter BF37_494 ENOG4105K8R UPF0145 protein BF37_4940 ENOG4107XGZ Hydrolase BF37_4944 ENOG4105C8J )-transporter BF37_4947 ENOG41062D9 Histidine kinase BF37_4948 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_4949 ENOG4107QPK )-transporter BF37_4950 ENOG4105BZW Glycerate kinase BF37_4968 ENOG4105EC2 ftsk spoIIIe BF37_4972 ENOG4105C5S asparaginyl-tRNA synthetase BF37_4973 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF37_4976 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BF37_4982 ENOG4105C75 arginyL-tRNA synthetase BF37_4983 ENOG4107YX5 Pfam:DUF548 BF37_4987 ENOG41061H0 Monooxygenase BF37_499 ENOG4105BZU Histidine kinase BF37_4990 ENOG4108UUM single-stranded DNA-binding protein BF37_4993 ENOG4105C5H ABC transporter BF37_4997 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF37_500 ENOG4105BZU Histidine kinase BF37_5000 ENOG4105MCT stage V sporulation protein S BF37_5007 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BF37_5008 ENOG4108IFG nitrite reductase, (NAD(P)H) BF37_5009 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BF37_501 ENOG4108MJI response regulator BF37_5010 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF37_5011 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF37_5012 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF37_5017 ENOG4108ZAF Molybdopterin BF37_5018 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF37_5019 ENOG4105D06 uba thif-type nad fad binding protein BF37_5020 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF37_5021 ENOG4107V6Q Cyclic nucleotide-binding domain BF37_5026 ENOG4105R3A Nitrate reductase BF37_5027 ENOG4108IUE nitrate reductase beta subunit BF37_503 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF37_5031 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF37_5034 ENOG4108V06 Glutathione peroxidase BF37_5039 ENOG4105EMN RNA polymerase sigma factor BF37_5040 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BF37_5042 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BF37_5043 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BF37_5047 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BF37_505 ENOG4105WN5 stage II sporulation protein BF37_5052 ENOG4105KBJ sporulation protein ytfj BF37_5061 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF37_5067 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF37_5068 ENOG4108JYZ YitT family BF37_5069 ENOG41087PP glycosyltransferase MGT family BF37_5072 ENOG4107RBS Methyltransferase BF37_5073 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF37_5075 ENOG4108X4Q Hydrolase BF37_5080 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF37_5082 ENOG4108VXD carboxy-peptidase BF37_5084 ENOG4108ZRV stage ii sporulation protein p BF37_5088 ENOG4108Z7R Chaperone CsaA BF37_5092 ENOG4105C37 (CBS) domain BF37_5093 ENOG4105SXS Protein of unknown function (DUF456) BF37_5097 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF37_5098 ENOG4108S4H thioesterase Superfamily protein BF37_51 ENOG4105BZU Histidine kinase BF37_5100 ENOG4108PJD permease BF37_5103 ENOG4107T5V SNARE associated Golgi BF37_5107 ENOG4105CVJ phosphoglycerate mutase BF37_5112 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF37_5114 ENOG4105K4T epimerase BF37_5116 ENOG4105DSE periplasmic solute binding protein BF37_5128 ENOG4105CKI cobalamin synthesis protein BF37_5129 ENOG4107QM2 Aldo Keto reductase BF37_5133 ENOG4105DEN Luciferase family BF37_5136 ENOG4108WPJ Ferritin-like domain BF37_5137 ENOG4108K88 Membrane BF37_5140 ENOG4105C8Q Methyl-accepting chemotaxis BF37_5145 ENOG4107XZQ multidrug resistance protein BF37_5146 ENOG4107SET aldo keto reductase BF37_5147 ENOG4105YVS arsR family transcriptional regulator BF37_5149 ENOG4105KRN Transcriptional regulator, abrb family BF37_5160 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BF37_5162 ENOG4107RCC Major Facilitator Superfamily BF37_5163 ENOG4105YWU small acid-soluble spore protein BF37_5164 ENOG4108WBH protein TIM barrel BF37_5167 ENOG4105CEY Amp-dependent synthetase and ligase BF37_5168 ENOG4105DUU IucA IucC family protein BF37_5170 ENOG4105VRR gCN5-related N-acetyltransferase BF37_5171 ENOG4105KT7 mgtC SapB transporter BF37_5173 ENOG4107VMI polysaccharide deacetylase BF37_5174 ENOG4105BZU Histidine kinase BF37_5175 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF37_5177 ENOG4108KGH TRANSCRIPTIONal BF37_518 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BF37_5182 ENOG4105D6E homoserine dehydrogenase BF37_5186 ENOG4108ZJ4 polysaccharide deacetylase BF37_5187 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BF37_5190 ENOG4105BZU Histidine kinase BF37_5191 ENOG4105EFI regulatoR BF37_5192 ENOG4105BZ1 (ABC) transporter BF37_5193 ENOG4105BZ1 (ABC) transporter BF37_5201 ENOG4108JJ8 (ABC) transporter BF37_5202 ENOG4108JJ9 ABC, transporter BF37_5203 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF37_5204 ENOG4105C4M (Ubiquinol oxidase) subunit I BF37_5206 ENOG4105YGB Transcriptional regulator BF37_5208 ENOG4105MDS 4-oxalocrotonate tautomerase BF37_5210 ENOG4105SKE transcriptional Regulator LysR family BF37_5212 ENOG4105C32 Amino acid ABC transporter (Permease) BF37_5213 ENOG4108IV0 ABC, transporter BF37_5214 ENOG4105C0Z ABC transporter BF37_5216 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF37_5217 ENOG4108Z7G MaoC domain protein dehydratase BF37_5221 ENOG4105CKI cobalamin synthesis protein BF37_5223 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF37_5224 ENOG4106F5Q Membrane BF37_5225 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF37_5227 ENOG4108TVJ Nitroreductase BF37_5228 ENOG4107ZXU DSBA oxidoreductase BF37_5229 ENOG4108Z40 Transcriptional regulator BF37_523 ENOG410847I Transcriptional regulator, BadM Rrf2 family BF37_5230 ENOG4105GZI Transcriptional regulator BF37_5231 ENOG4107RT3 EamA-like transporter family BF37_5233 ENOG4105KTB nuclear export factor GLE1 BF37_5234 ENOG4108T5E Copper resistance protein BF37_524 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BF37_5244 ENOG4107STQ Multicopper oxidase BF37_5245 ENOG4107RAQ aminopeptidase BF37_525 ENOG4105CMT Dihydroxyacetone kinase BF37_5251 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BF37_5252 ENOG4105D9N nucleoside BF37_5254 ENOG4107RHR regulatoR BF37_5259 ENOG4105C0X amino acid BF37_5260 ENOG4105C0X amino acid BF37_5262 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BF37_5264 ENOG4105C72 UPF0176 protein BF37_5265 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BF37_527 ENOG4105CMT Dihydroxyacetone kinase BF37_5270 ENOG41068WN BF37_5276 ENOG4108J59 Extracellular solute-binding protein, family 5 BF37_5277 ENOG4105F6J Alpha beta hydrolase fold BF37_5281 ENOG4105CYC Transferase BF37_5282 ENOG4105DY9 regulatoR BF37_5284 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BF37_5285 ENOG4105C6X Major Facilitator BF37_5290 ENOG4105C7B Threonine dehydratase BF37_5292 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BF37_5293 ENOG4108ZP8 Acetolactate synthase small subunit BF37_5294 ENOG4105C7K acetolactate synthase BF37_5295 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF37_5296 ENOG4105CHR reductase BF37_5297 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BF37_5301 ENOG4106KE4 Dehydrogenase BF37_5304 ENOG4105H67 Protein of unknown function (DUF421) BF37_5305 ENOG4105X5K response regulator receiver protein BF37_5307 ENOG4105C8J )-transporter BF37_531 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF37_5311 ENOG4105C6T cysteine synthase BF37_5312 ENOG4105EU0 Major facilitator Superfamily BF37_5315 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF37_5318 ENOG4105DXI Major Facilitator superfamily BF37_5319 ENOG4105DXI Major Facilitator superfamily BF37_5320 ENOG4105CSR polyphosphate kinase 2 BF37_5328 ENOG4105FVX BF37_5341 ENOG4105C6K Malic enzyme BF37_5342 ENOG4108IJ0 Aspartate ammonia-lyase BF37_5344 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BF37_5348 ENOG4105CJ1 ABC, transporter BF37_535 ENOG4108IG5 Transcriptional regulator BF37_5355 ENOG4106BRA Membrane BF37_536 ENOG4107P5I polyketide synthase BF37_5362 ENOG4107QIV Cytochrome c biogenesis protein BF37_5366 ENOG4105EC3 peptidase S51, dipeptidase E BF37_5367 ENOG4107QJQ Mate efflux family protein BF37_5368 ENOG4107QJQ Mate efflux family protein BF37_5372 ENOG4105C9Q fumarate hydratase class II BF37_5373 ENOG4105DFD Na H antiporter BF37_5376 ENOG4108PJD permease BF37_5377 ENOG4105CKI cobalamin synthesis protein BF37_5378 ENOG4108UZ3 Transporter BF37_5379 ENOG4105DRR Transcriptional regulator, GntR family BF37_5381 ENOG4105PGM cation diffusion facilitator family transporter BF37_5385 ENOG4105CAQ asparagine synthetase BF37_5392 ENOG4105CVJ phosphoglycerate mutase BF37_5399 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BF37_54 ENOG4105I3N Conserved Protein BF37_5400 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BF37_5401 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF37_5402 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF37_5403 ENOG4105DUM transcriptional regulator, lysR family BF37_5408 ENOG4105KAC Antibiotic biosynthesis monooxygenase BF37_5412 ENOG4108RZE Tetr family transcriptional regulator BF37_5417 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF37_5418 ENOG4105KTQ flagellar basal-body rod protein BF37_5419 ENOG4105FZW flagellar biosynthesis regulator FlhF BF37_5420 ENOG4105D7B Flagellar biosynthesis protein flha BF37_5421 ENOG4105D00 flagellar biosynthetic protein flhB BF37_5423 ENOG4105VS8 Flagellar biosynthetic protein fliq BF37_5427 ENOG4105DD5 Flagellar motor switch protein BF37_5429 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF37_5430 ENOG4105E4C Lytic transglycosylase catalytic BF37_5431 ENOG4105I03 Flagellin BF37_5436 ENOG4107TVC Glycosyl transferase, family 2 BF37_5442 ENOG4105K64 Glycosyl transferase, family 2 BF37_5444 ENOG4107R88 Chemotaxis protein (CheV) BF37_5456 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF37_5458 ENOG4107U2N Flagellar M-ring protein BF37_5459 ENOG41075Z6 flagellar hook-basal body complex protein fliE BF37_546 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_5460 ENOG4108ZC9 flagellar basal-body rod protein flgc BF37_5461 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BF37_5466 ENOG4105DTJ flagellar hook-associated protein BF37_5467 ENOG4105E1Q flagellar hook-associated protein BF37_5471 ENOG4105BZU Histidine kinase BF37_5474 ENOG4105DD5 Flagellar motor switch protein BF37_5475 ENOG4105CBS Chea signal transduction histidine kinase BF37_5476 ENOG4105CBS Chea signal transduction histidine kinase BF37_5477 ENOG4107YTP response regulator receiver protein BF37_5478 ENOG4105ER2 Ompa motb domain protein BF37_5479 ENOG4107R0U MotA TolQ exbB proton channel BF37_5481 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BF37_5492 ENOG41080C8 DUF218 domain BF37_5493 ENOG4105H67 Protein of unknown function (DUF421) BF37_5495 ENOG4108Z5V transcriptional regulator, merr family BF37_5496 ENOG4105CN5 Metallo-Beta-Lactamase BF37_5497 ENOG4107RWR Sodium hydrogen exchanger BF37_5499 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF37_55 ENOG4105BZU Histidine kinase BF37_5512 ENOG41081VK Ribonuclease BF37_5516 ENOG4108SZE gCN5-related N-acetyltransferase BF37_5519 ENOG4105CPK Glycosyl transferase (Group 1 BF37_5534 ENOG4106032 Glutathionylspermidine synthase BF37_5537 ENOG4105KHC sulfurtransferase BF37_5539 ENOG4108W0I acetyltransferase BF37_554 ENOG4105CDU Replicative dna helicase BF37_5541 ENOG410890F Dynamin family BF37_5543 ENOG4105DHF Membrane BF37_5544 ENOG4105C2W permease BF37_5546 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF37_5549 ENOG4105CTD carboxy-peptidase BF37_5550 ENOG4105DVT helicase BF37_5552 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BF37_5563 ENOG4105BZ4 penicillin-binding protein BF37_5565 ENOG4105CSM endonuclease III BF37_5569 ENOG4105YAC BF37_5570 ENOG4105DVT helicase BF37_5577 ENOG4105CPK Glycosyl transferase (Group 1 BF37_5578 ENOG4105FJR Lmbe family BF37_5581 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BF37_5582 ENOG4108JYZ YitT family BF37_5588 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BF37_5589 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BF37_5590 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BF37_5593 ENOG41068YB TPR repeat-containing protein BF37_5594 ENOG4105CIH Imidazole acetol-phosphate transaminase BF37_5598 ENOG4105EAH synthase BF37_5600 ENOG4105XXQ heptaprenyl diphosphate synthase component I BF37_5611 ENOG4105KRN Transcriptional regulator, abrb family BF37_5613 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF37_5620 ENOG4108IBT Inherit from COG: transposase BF37_5622 ENOG4105DQ6 Transposase BF37_5625 ENOG4105DQ6 Transposase BF37_5627 ENOG4105DQ6 Transposase BF37_5629 ENOG4108MEK Metal-binding protein YodA BF37_563 ENOG4108MRH transcriptional regulatory protein BF37_5631 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BF37_5638 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BF37_565 ENOG4105CSH Transporter BF37_5659 ENOG4105EKQ RNA-directed DNA polymerase BF37_5680 ENOG4105EKQ RNA-directed DNA polymerase BF37_5692 ENOG4106JUT Streptomycin 3''-adenylyltransferase BF37_5706 ENOG4105CNU cell division protein FtsK BF37_571 ENOG4108JQ7 (ABC) transporter BF37_574 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF37_5755 ENOG4105DHF Membrane BF37_5761 ENOG4106AKK s-layer domain-containing protein BF37_5762 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF37_5766 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF37_5767 ENOG4105C6Y Udp-glucose 6-dehydrogenase BF37_5768 ENOG4105C6Y Udp-glucose 6-dehydrogenase BF37_5772 ENOG4105DQ6 Transposase BF37_5780 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BF37_58 ENOG4105BZ4 penicillin-binding protein BF37_5805 ENOG4105N14 lysine exporter protein LysE YggA BF37_5811 ENOG4108J59 Extracellular solute-binding protein, family 5 BF37_5813 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF37_582 ENOG4105CTU Proline racemase BF37_5823 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF37_5824 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF37_5838 ENOG4105K4H Nlp p60 protein BF37_586 ENOG4105DER m42 family BF37_5872 ENOG4107QJE Chromosome Partitioning Protein BF37_5877 ENOG4105DQ6 Transposase BF37_5884 ENOG4105EWC Purine nucleoside phosphorylase BF37_589 ENOG4105CGU Enoyl-CoA hydratase BF37_59 ENOG4107GRR phosphate transport regulator BF37_592 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF37_593 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF37_595 ENOG4106AKK s-layer domain-containing protein BF37_60 ENOG4105CJ3 phosphate transporter BF37_603 ENOG4105CHH sulfate transporter BF37_606 ENOG4105D4P Coproporphyrinogen iii oxidase BF37_613 ENOG4107FQX Alpha-acetolactate decarboxylase BF37_620 ENOG410839P BF37_623 ENOG4105CDA abc transporter atp-binding protein BF37_624 ENOG4105DRP amino acid AbC transporter BF37_626 ENOG4105BZ1 (ABC) transporter BF37_627 ENOG4105BZ1 (ABC) transporter BF37_628 ENOG4105BZ1 (ABC) transporter BF37_629 ENOG4105C26 Dehydrogenase BF37_631 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BF37_632 ENOG4105D5Q Arginine ornithine antiporter BF37_634 ENOG4105CH6 catalase BF37_635 ENOG4107RKG DJ-1/PfpI family BF37_637 ENOG4105E5W Transporter BF37_638 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF37_639 ENOG4105NF4 modulator of drug activity BF37_64 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BF37_644 ENOG4105KPY Small multidrug resistance protein BF37_645 ENOG4105KPY Small multidrug resistance protein BF37_647 ENOG4108YXU transcriptional regulator AsnC family BF37_648 ENOG4108PCN EamA-like transporter family BF37_655 ENOG4106KNT transcriptional regulator BF37_657 ENOG4107RWR Sodium hydrogen exchanger BF37_658 ENOG4105CUB amino acid BF37_665 ENOG4107T5V SNARE associated Golgi BF37_672 ENOG4105WEF catalase BF37_678 ENOG4105C19 ABC transporter BF37_679 ENOG4107RBB ABC transporter, permease BF37_680 ENOG41069ER domain protein BF37_684 ENOG4105VZJ PTS System BF37_685 ENOG4105VCP PTS System BF37_686 ENOG4105EMD TRANSCRIPTIONal BF37_69 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BF37_691 ENOG4108KGH TRANSCRIPTIONal BF37_693 ENOG41087NI Sulfite exporter TauE/SafE BF37_694 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BF37_696 ENOG41085GJ domain protein BF37_698 ENOG4105VFE sira family BF37_699 ENOG4107TPS domain protein BF37_700 ENOG4105VFE sira family BF37_701 ENOG4105XTG Pfam:DUF156 BF37_702 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BF37_707 ENOG4105ED1 spovr family BF37_708 ENOG4107Y03 Nitroreductase BF37_713 ENOG4108B31 Spore germination protein BF37_720 ENOG4105C5Y PTS System BF37_727 ENOG4105C7N Xanthine uracil vitamin C permease BF37_73 ENOG4105WH1 Two component transcriptional regulator luxr family BF37_730 ENOG4108INS Transcriptional regulator BF37_739 ENOG4105DWF phosphomethylpyrimidine kinase BF37_74 ENOG4105ENE Histidine kinase BF37_740 ENOG4105D06 uba thif-type nad fad binding protein BF37_743 ENOG41080HI glycine oxidase BF37_744 ENOG4108VEU Thiamine monophosphate synthase BF37_746 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF37_748 ENOG4105ETU transcriptional activator (TenA BF37_752 ENOG41080XQ Signal transduction protein with cbs domains BF37_779 ENOG4105E2Z phosphate ABC transporter (Permease BF37_78 ENOG4105DFD Na H antiporter BF37_780 ENOG4105C8U phosphate abc transporter BF37_781 ENOG4105CVA phosphate BF37_782 ENOG4105CE1 Ferrous iron transport protein b BF37_783 ENOG4105CE1 Ferrous iron transport protein b BF37_784 ENOG4105CE1 Ferrous iron transport protein b BF37_785 ENOG4108NHD germination protein BF37_788 ENOG4105E1V na solute symporter BF37_789 ENOG4106CAD Protein of unknown function (DUF3311) BF37_792 ENOG4105E2S oxidase) subunit II BF37_793 ENOG4105BZ9 Cytochrome C oxidase, subunit I BF37_8 ENOG41065D1 BF37_801 ENOG4105C7N Xanthine uracil vitamin C permease BF37_802 ENOG4105C85 amino acid BF37_806 ENOG4105DUX Transporter BF37_808 ENOG4107D63 BF37_809 ENOG4105VZ8 Transcriptional regulator BF37_810 ENOG41069ER domain protein BF37_811 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF37_812 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BF37_82 ENOG4105C8J )-transporter BF37_824 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF37_825 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF37_826 ENOG4105CNN ABC, transporter BF37_827 ENOG4105C2J ABC transporter BF37_829 ENOG4108RVA ribokinase BF37_83 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF37_830 ENOG4105ETE Transcriptional regulator (LacI family BF37_831 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_832 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF37_833 ENOG41067TZ transcriptional regulator, MarR family BF37_834 ENOG4105CXY transporter BF37_836 ENOG4108JQ7 (ABC) transporter BF37_837 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF37_839 ENOG4105DEF Extracellular solute-binding protein, family 5 BF37_84 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF37_841 ENOG41068KF Universal stress protein BF37_842 ENOG4105CHH sulfate transporter BF37_845 ENOG4105BZU Histidine kinase BF37_846 ENOG4105NAE bifunctional deaminase-reductase domain protein BF37_847 ENOG4105D29 Helix-turn-helix type 11 domain protein BF37_85 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF37_852 ENOG4108IQI permease BF37_853 ENOG4105DRP amino acid AbC transporter BF37_854 ENOG4105EAD ABC transporter BF37_855 ENOG4105CT1 (ABC) transporter BF37_856 ENOG4105CDA abc transporter atp-binding protein BF37_857 ENOG4105BZG amino acid carrier protein BF37_858 ENOG4105CRN Aminoglycoside phosphotransferase BF37_860 ENOG4105E1K spore germination protein BF37_863 ENOG4105CG3 alpha amylase, catalytic region BF37_864 ENOG4105C5Y PTS System BF37_865 ENOG4107414 GntR family transcriptional regulator BF37_866 ENOG4105D5Q Arginine ornithine antiporter BF37_867 ENOG4105BZU Histidine kinase BF37_87 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BF37_870 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF37_871 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BF37_872 ENOG4107T89 von Willebrand factor, type A BF37_874 ENOG4105EXW epimerase dehydratase BF37_876 ENOG4105DMQ Methyltransferase BF37_877 ENOG4105E0A ABC, transporter BF37_878 ENOG4108IHU transport system permease protein BF37_879 ENOG4105DQ5 transport system permease protein BF37_88 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BF37_880 ENOG4108MES Periplasmic binding protein BF37_881 ENOG4105DUX Transporter BF37_884 ENOG4105DAA L-lactate BF37_885 ENOG4108IJ0 Aspartate ammonia-lyase BF37_886 ENOG4105C37 (CBS) domain BF37_887 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BF37_888 ENOG4105D9N nucleoside BF37_889 ENOG4108KGH TRANSCRIPTIONal BF37_890 ENOG41073R8 VanW family BF37_897 ENOG4105DAP Nicotinate phosphoribosyltransferase BF37_898 ENOG4105C59 p-type ATPase BF37_9 ENOG4105S2F BF37_900 ENOG4105CUB amino acid BF37_905 ENOG4108JB9 formate dehydrogenase BF37_906 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF37_907 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF37_909 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF37_910 ENOG4105BZU Histidine kinase BF37_912 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF37_913 ENOG4108UZ3 Transporter BF37_915 ENOG4105C6K Malic enzyme BF37_917 ENOG4108MRH transcriptional regulatory protein BF37_92 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BF37_922 ENOG4105US7 Histidine kinase BF37_923 ENOG4108STX response regulator BF37_924 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BF37_925 ENOG4105BZ7 extracellular solute-binding protein family 1 BF37_926 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BF37_927 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BF37_928 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF37_929 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF37_933 ENOG4105D4T Citrate transporter BF37_934 ENOG4108MRH transcriptional regulatory protein BF37_935 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BF37_937 ENOG4105DZ6 Band 7 protein BF37_94 ENOG4105E0M Sulfatase BF37_940 ENOG4105C94 Transporter BF37_944 ENOG4105CYN Serine protein kinase BF37_946 ENOG4105BZU Histidine kinase BF37_947 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BF37_949 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BF37_95 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF37_951 ENOG4107ZQN disulfide bond BF37_952 ENOG4108JQC penicillin-binding protein 1A BF37_977 ENOG4105G5W regulator Fur family BF37_978 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF37_98 ENOG4107RVV histidinol phosphate phosphatase, hisj family BF37_982 ENOG4108IUW ABC transporter BF37_984 ENOG4105CBC glutamate synthase BF37_985 ENOG4107NBY Membrane BF37_986 ENOG4105BZ1 (ABC) transporter BF37_990 ENOG4106BXE BF37_991 ENOG4105CEN a g-specific adenine glycosylase BF37_992 ENOG41067AE Membrane-bound metal-dependent hydrolase BF37_998 ENOG4105ECP epimerase BF37_999 ENOG4105CI2 imidazolone-5-propionate hydrolase