locus-tag	class	description
BF37_1003	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF37_1006	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF37_1006	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF37_1009	COG0463	Glycosyl transferase, family 2
BF37_1012	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF37_1013	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_1013	COG1263	PTS System
BF37_1014	COG2066	Belongs to the glutaminase family
BF37_1019	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF37_1020	COG0833	amino acid
BF37_1022	COG3829	transcription factor binding
BF37_1024	COG0101	tRNA pseudouridine synthase activity
BF37_105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF37_1071	COG1484	DNA-dependent DNA replication
BF37_1078	COG1396	sequence-specific DNA binding
BF37_1082	COG0582	viral genome integration into host DNA
BF37_1083	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF37_1084	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF37_1089	COG0535	radical SAM domain protein
BF37_1091	COG0387	Pfam Sodium calcium exchanger
BF37_1092	COG3871	stress protein (general stress protein 26)
BF37_1095	COG0586	Pfam SNARE associated Golgi protein
BF37_1098	COG0681	Belongs to the peptidase S26 family
BF37_110	COG0473	3-isopropylmalate dehydrogenase activity
BF37_1100	COG0697	spore germination
BF37_1101	COG2217	Heavy metal translocating P-type atpase
BF37_1102	COG1295	ribonuclease BN
BF37_1104	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF37_1107	COG3853	Toxic anion resistance protein (TelA)
BF37_1109	COG0861	Integral membrane protein TerC family
BF37_1110	COG2310	stress, protein
BF37_1111	COG2310	stress, protein
BF37_1112	COG2310	stress, protein
BF37_1115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF37_1118	COG2270	Major facilitator Superfamily
BF37_112	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF37_1127	COG0488	(ABC) transporter
BF37_1128	COG1116	anion transmembrane transporter activity
BF37_113	COG0440	acetolactate synthase activity
BF37_1130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF37_1133	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF37_1139	COG2190	(PTS) system
BF37_1139	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_1139	COG1263	PTS System
BF37_114	COG0028	Belongs to the TPP enzyme family
BF37_1140	COG0366	Alpha amylase catalytic
BF37_1141	COG0840	transmembrane signaling receptor activity
BF37_1142	COG0840	transmembrane signaling receptor activity
BF37_1144	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF37_1145	COG0765	amino acid transport
BF37_1147	COG0723	plastoquinol--plastocyanin reductase activity
BF37_1147	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF37_1148	COG2814	Major facilitator Superfamily
BF37_1149	COG3541	Predicted nucleotidyltransferase
BF37_115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF37_1153	COG5002	protein histidine kinase activity
BF37_1159	COG0166	Belongs to the GPI family
BF37_1162	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_1163	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_1164	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_1165	COG0235	Class ii aldolase
BF37_1167	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF37_1168	COG0450	alkyl hydroperoxide reductase
BF37_1171	COG1473	amidohydrolase
BF37_1177	COG4807	Protein conserved in bacteria
BF37_1179	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF37_1180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF37_1181	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_1184	COG2309	aminopeptidase activity
BF37_1185	COG2076	Multidrug Resistance protein
BF37_1186	COG1012	belongs to the aldehyde dehydrogenase family
BF37_1188	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF37_1189	COG0546	phosphoglycolate phosphatase activity
BF37_1190	COG1597	lipid kinase activity
BF37_1194	COG4682	membrane
BF37_1195	COG1846	Transcriptional regulator
BF37_1196	COG0003	Pfam Anion-transporting ATPase
BF37_1197	COG0003	Pfam Anion-transporting ATPase
BF37_120	COG3874	Sporulation protein YtfJ
BF37_1200	COG1464	Belongs to the NlpA lipoprotein family
BF37_1201	COG2011	ABC-type metal ion transport system permease component
BF37_1202	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF37_1203	COG1335	isochorismatase
BF37_1207	COG4851	CamS sex pheromone cAM373 precursor
BF37_1209	COG0210	DNA helicase
BF37_121	COG4709	membrane
BF37_1214	COG0151	Belongs to the GarS family
BF37_1216	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF37_1218	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF37_122	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF37_1221	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF37_1223	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF37_1224	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF37_1225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF37_123	COG1301	dicarboxylic acid transport
BF37_1230	COG0745	RESPONSE REGULATOR receiver
BF37_1231	COG2205	protein histidine kinase activity
BF37_1234	COG1968	undecaprenyl-diphosphatase activity
BF37_1239	COG1215	transferase activity, transferring glycosyl groups
BF37_1244	COG2226	methyltransferase
BF37_125	COG1846	Transcriptional regulator
BF37_1252	COG5002	protein histidine kinase activity
BF37_1254	COG2252	PERMEase
BF37_1258	COG1266	CAAX protease self-immunity
BF37_1261	COG0488	(ABC) transporter
BF37_1262	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF37_1263	COG0456	acetyltransferase
BF37_1264	COG1214	PFAM Peptidase M22, glycoprotease
BF37_1265	COG0802	atpase or kinase
BF37_128	COG1968	undecaprenyl-diphosphatase activity
BF37_1284	COG2183	response to ionizing radiation
BF37_1285	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF37_1286	COG0864	Transcriptional regulator
BF37_1287	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF37_1288	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF37_129	COG0534	Mate efflux family protein
BF37_1290	COG4294	response to UV
BF37_1291	COG0457	Tetratricopeptide repeat
BF37_1291	COG0705	Rhomboid family
BF37_1293	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF37_1296	COG2814	Major facilitator Superfamily
BF37_1298	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF37_1299	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF37_1305	COG0561	phosphatase activity
BF37_1306	COG0561	phosphatase activity
BF37_1307	COG4608	Belongs to the ABC transporter superfamily
BF37_1308	COG0444	Belongs to the ABC transporter superfamily
BF37_1310	COG0601	transmembrane transport
BF37_1311	COG0747	negative chemotaxis
BF37_1314	COG0488	(ABC) transporter
BF37_1318	COG5298	Protein conserved in bacteria
BF37_1319	COG0084	hydrolase, TatD family'
BF37_1322	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_1324	COG1609	Transcriptional regulator
BF37_1326	COG0204	Acyl-transferase
BF37_1329	COG0697	spore germination
BF37_133	COG3173	Aminoglycoside phosphotransferase
BF37_1330	COG0583	DNA-binding transcription factor activity
BF37_1333	COG1910	domain protein
BF37_1334	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF37_1335	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF37_1336	COG4149	molybdate abc transporter
BF37_1339	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF37_1340	COG0656	L-ascorbic acid biosynthetic process
BF37_1341	COG4166	transmembrane transport
BF37_1342	COG4166	transmembrane transport
BF37_1345	COG2207	Transcriptional regulator
BF37_1347	COG4166	transmembrane transport
BF37_1348	COG4608	Belongs to the ABC transporter superfamily
BF37_1349	COG0444	Belongs to the ABC transporter superfamily
BF37_1350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF37_1351	COG0601	transmembrane transport
BF37_1354	COG2814	Major facilitator Superfamily
BF37_1356	COG2271	Major facilitator Superfamily
BF37_1357	COG0277	FAD linked oxidase domain protein
BF37_136	COG0716	FMN binding
BF37_1360	COG1464	Belongs to the NlpA lipoprotein family
BF37_1361	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF37_1362	COG2011	ABC-type metal ion transport system permease component
BF37_1363	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_1371	COG0823	Involved in the tonB-independent uptake of proteins
BF37_1371	COG1506	peptidase
BF37_1371	COG4946	Tricorn protease homolog
BF37_1372	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF37_1377	COG0596	Alpha beta hydrolase
BF37_1378	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF37_1380	COG4856	YbbR-like protein
BF37_1381	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF37_1399	COG0726	polysaccharide deacetylase
BF37_1400	COG2194	sulfuric ester hydrolase activity
BF37_1402	COG0489	protein tyrosine kinase activity
BF37_1403	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF37_1407	COG0101	tRNA pseudouridine synthase activity
BF37_1408	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF37_1409	COG1122	ATPase activity
BF37_141	COG1696	Membrane protein involved in D-alanine export
BF37_1415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF37_1417	COG0024	Methionine aminopeptidase
BF37_1419	COG0201	protein transport
BF37_1424	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF37_143	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF37_144	COG2070	2-Nitropropane dioxygenase
BF37_1445	COG1358	cellular component organization or biogenesis
BF37_1446	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF37_1448	COG2813	Specifically methylates the guanine in position
BF37_145	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF37_1453	COG0250	Participates in transcription elongation, termination and antitermination
BF37_1454	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF37_1456	COG3688	RNA-binding protein containing a PIN domain
BF37_1457	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF37_1460	COG1045	serine acetyltransferase
BF37_1464	COG4956	integral membrane protein (PIN domain superfamily)
BF37_1466	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF37_1467	COG0542	response to heat
BF37_1469	COG3880	PFAM UvrB UvrC protein
BF37_147	COG1335	isochorismatase
BF37_1476	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF37_1477	COG1396	sequence-specific DNA binding
BF37_1478	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF37_1479	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF37_1480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF37_1481	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF37_1482	COG0512	Glutamine amidotransferase of anthranilate synthase
BF37_1483	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF37_1484	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF37_1487	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF37_1489	COG0037	tRNA processing
BF37_149	COG1522	sequence-specific DNA binding
BF37_1490	COG2208	phosphoserine phosphatase activity
BF37_1493	COG1098	S1 RNA binding domain
BF37_1497	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF37_1498	COG3956	TIGRFAM MazG family protein
BF37_1499	COG2244	polysaccharide biosynthetic process
BF37_1500	COG2002	toxin-antitoxin pair type II binding
BF37_1501	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF37_1503	COG0193	aminoacyl-tRNA hydrolase activity
BF37_1504	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF37_1507	COG0251	oxidation-reduction process
BF37_1508	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF37_1511	COG4466	Protein conserved in bacteria
BF37_1514	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF37_1515	COG0084	hydrolase, TatD family'
BF37_1516	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_1516	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_1517	COG2002	toxin-antitoxin pair type II binding
BF37_1518	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF37_152	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF37_1520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF37_1522	COG1774	PSP1 C-terminal conserved region
BF37_1523	COG0470	DNA polymerase III
BF37_1525	COG1982	Orn Lys Arg decarboxylase major
BF37_153	COG1131	(ABC) transporter
BF37_1537	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF37_1538	COG0590	tRNA wobble adenosine to inosine editing
BF37_1539	COG1335	isochorismatase
BF37_1540	COG1428	Deoxynucleoside kinase
BF37_1541	COG1428	Deoxynucleoside kinase
BF37_1547	COG1686	Belongs to the peptidase S11 family
BF37_1548	COG0517	IMP dehydrogenase activity
BF37_1548	COG0516	GMP reductase activity
BF37_155	COG1131	(ABC) transporter
BF37_1556	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF37_1557	COG0187	DNA topoisomerase II activity
BF37_1559	COG2501	S4 domain
BF37_156	COG1725	Transcriptional regulator
BF37_1560	COG0592	DNA-directed DNA polymerase activity
BF37_1564	COG0706	membrane insertase activity
BF37_1565	COG1847	R3H domain protein
BF37_1566	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF37_157	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF37_1570	COG1192	Involved in chromosome partitioning
BF37_1571	COG1475	DNA binding
BF37_1573	COG0668	transmembrane transport
BF37_1574	COG4481	Protein conserved in bacteria
BF37_1575	COG0012	GTP binding
BF37_1577	COG0629	single-stranded DNA binding
BF37_1579	COG4241	membrane
BF37_158	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF37_1580	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF37_1582	COG0305	Participates in initiation and elongation during chromosome replication
BF37_1588	COG0745	RESPONSE REGULATOR receiver
BF37_1589	COG5002	protein histidine kinase activity
BF37_1590	COG4863	YycH protein
BF37_1591	COG4853	Protein conserved in bacteria
BF37_1592	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF37_1593	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF37_1597	COG1164	Oligoendopeptidase f
BF37_1598	COG0516	GMP reductase activity
BF37_16	COG0252	asparaginase activity
BF37_160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF37_1602	COG1272	protein, Hemolysin III
BF37_1603	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF37_1607	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF37_1608	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF37_1609	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF37_161	COG1780	Probably involved in ribonucleotide reductase function
BF37_1610	COG2814	Major facilitator Superfamily
BF37_1611	COG3275	phosphorelay sensor kinase activity
BF37_1612	COG3279	Response regulator of the LytR AlgR family
BF37_1615	COG0628	permease
BF37_1616	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF37_1616	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF37_1617	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF37_1618	COG1309	transcriptional regulator
BF37_1619	COG0463	Glycosyl transferase, family 2
BF37_1624	COG0488	(ABC) transporter
BF37_1627	COG1607	acyl-coa hydrolase
BF37_1629	COG0840	transmembrane signaling receptor activity
BF37_1634	COG0477	Major facilitator Superfamily
BF37_1635	COG3279	Response regulator of the LytR AlgR family
BF37_1636	COG1966	Carbon starvation protein
BF37_1637	COG2879	small protein
BF37_1638	COG3706	GGDEF domain
BF37_1639	COG0351	phosphomethylpyrimidine kinase
BF37_1640	COG4585	Histidine kinase
BF37_1640	COG2203	Gaf domain
BF37_1641	COG2203	Gaf domain
BF37_1641	COG4585	Histidine kinase
BF37_1642	COG2197	response regulator
BF37_1644	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF37_1645	COG1011	Hydrolase
BF37_1650	COG0460	homoserine dehydrogenase
BF37_1652	COG1609	Transcriptional regulator
BF37_1653	COG2755	lipolytic protein G-D-S-L family
BF37_1654	COG1131	(ABC) transporter
BF37_1655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF37_1657	COG2814	Major facilitator Superfamily
BF37_1658	COG0561	phosphatase activity
BF37_1659	COG2233	PERMEase
BF37_1660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF37_1662	COG2363	Small membrane protein
BF37_1664	COG3773	Cell wall hydrolase
BF37_1667	COG0280	phosphate acetyltransferase
BF37_1668	COG0095	Lipoate-protein ligase
BF37_167	COG4873	Protein conserved in bacteria
BF37_1672	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_1673	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_1674	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_1675	COG1120	ATPase activity
BF37_1676	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_1677	COG1078	dGTPase activity
BF37_1679	COG1994	Peptidase M50
BF37_1681	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF37_1682	COG0584	glycerophosphoryl diester phosphodiesterase
BF37_1683	COG0789	Transcriptional regulator
BF37_1684	COG2814	Major facilitator Superfamily
BF37_1685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF37_1686	COG0010	Belongs to the arginase family
BF37_1689	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF37_1690	COG4506	Protein conserved in bacteria
BF37_1691	COG0018	arginyl-trna synthetase
BF37_1692	COG1595	DNA-templated transcription, initiation
BF37_1696	COG2234	aminopeptidase activity
BF37_17	COG0492	ferredoxin-NADP+ reductase activity
BF37_170	COG0720	synthase
BF37_1700	COG0024	Methionine aminopeptidase
BF37_1701	COG1131	(ABC) transporter
BF37_1702	COG0842	Transport permease protein
BF37_1703	COG4585	Histidine kinase
BF37_1704	COG2197	response regulator
BF37_1708	COG3300	MHYT domain
BF37_1708	COG5001	Diguanylate cyclase
BF37_1710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF37_1711	COG2181	nitrate reductase activity
BF37_1711	COG0247	lactate metabolic process
BF37_1712	COG0183	Belongs to the thiolase family
BF37_1713	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF37_1714	COG1960	acyl-CoA dehydrogenase activity
BF37_1715	COG1960	acyl-CoA dehydrogenase activity
BF37_1717	COG3343	RNA polymerase activity
BF37_1719	COG4821	SIS domain
BF37_172	COG5002	protein histidine kinase activity
BF37_1722	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF37_1723	COG1494	fructose-1,6-bisphosphatase
BF37_1724	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF37_1727	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF37_1728	COG2890	protein-(glutamine-N5) methyltransferase activity
BF37_1731	COG0009	L-threonylcarbamoyladenylate synthase
BF37_1734	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF37_1735	COG2259	Doxx family
BF37_1736	COG2190	(PTS) system
BF37_1738	COG0698	ribose 5-phosphate isomerase
BF37_174	COG2318	DinB family
BF37_1744	COG0356	it plays a direct role in the translocation of protons across the membrane
BF37_1754	COG5001	Diguanylate cyclase
BF37_1754	COG3300	MHYT domain
BF37_1755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF37_1757	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF37_1758	COG0649	NAD binding
BF37_176	COG1846	Transcriptional regulator
BF37_1761	COG0839	Belongs to the complex I subunit 6 family
BF37_1763	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF37_1764	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF37_1765	COG1007	ATP synthesis coupled electron transport
BF37_1766	COG4836	Membrane
BF37_1768	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF37_1769	COG2385	sporulation resulting in formation of a cellular spore
BF37_177	COG3852	Histidine kinase
BF37_1770	COG4555	ABC transporter
BF37_1771	COG3279	Response regulator of the LytR AlgR family
BF37_1774	COG0739	heme binding
BF37_1776	COG1609	Transcriptional regulator
BF37_1785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF37_1786	COG1682	transport, permease protein
BF37_1789	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF37_179	COG2861	carbohydrate metabolic process
BF37_1792	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF37_1793	COG0745	RESPONSE REGULATOR receiver
BF37_1794	COG5002	protein histidine kinase activity
BF37_1801	COG1136	(ABC) transporter
BF37_1802	COG0577	efflux transmembrane transporter activity
BF37_1804	COG1191	sigma factor activity
BF37_1810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF37_1811	COG4715	Zinc finger, swim domain protein
BF37_1816	COG1388	LysM domain
BF37_1816	COG3584	3D domain protein
BF37_1817	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF37_1819	COG1215	transferase activity, transferring glycosyl groups
BF37_182	COG0235	Class ii aldolase
BF37_1821	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_1822	COG1388	LysM domain
BF37_1822	COG0791	NLP P60 protein
BF37_1825	COG1368	sulfuric ester hydrolase activity
BF37_1828	COG2389	metal-binding protein
BF37_1830	COG1620	l-lactate permease
BF37_1832	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF37_1833	COG1294	oxidase, subunit
BF37_1834	COG1271	oxidase subunit
BF37_1837	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF37_1838	COG0583	DNA-binding transcription factor activity
BF37_1839	COG1511	domain protein
BF37_1840	COG0346	lactoylglutathione lyase activity
BF37_1842	COG1301	dicarboxylic acid transport
BF37_1843	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF37_1845	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF37_1846	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF37_1847	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF37_1849	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF37_1850	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF37_1851	COG1486	melibiose metabolic process
BF37_1852	COG3394	polysaccharide catabolic process
BF37_1855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF37_1855	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF37_1857	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF37_1858	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF37_1859	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF37_1860	COG1316	TRANSCRIPTIONal
BF37_1861	COG1739	Uncharacterized protein family UPF0029
BF37_1862	COG1307	EDD domain protein, DegV family
BF37_1863	COG1733	regulation of RNA biosynthetic process
BF37_1864	COG1388	LysM domain
BF37_1864	COG0791	NLP P60 protein
BF37_1865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF37_1866	COG1040	competence protein
BF37_1867	COG1278	Cold shock
BF37_1868	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF37_1869	COG0653	protein targeting
BF37_187	COG1349	DNA-binding transcription factor activity
BF37_1870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF37_1872	COG2884	Cell division ATP-binding protein ftsE
BF37_1873	COG2177	Part of the ABC transporter FtsEX involved in
BF37_1874	COG3409	Peptidoglycan-binding domain 1 protein
BF37_1874	COG0793	Belongs to the peptidase S41A family
BF37_1875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF37_1876	COG1132	(ABC) transporter
BF37_1879	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF37_1881	COG0583	DNA-binding transcription factor activity
BF37_1882	COG2855	membrane
BF37_1886	COG0789	Transcriptional regulator
BF37_1890	COG0556	nucleotide-excision repair
BF37_1891	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF37_1893	COG1950	PFAM Membrane protein of
BF37_1897	COG0110	maltose O-acetyltransferase activity
BF37_1898	COG0457	Tetratricopeptide repeat
BF37_1899	COG0492	ferredoxin-NADP+ reductase activity
BF37_1901	COG1051	belongs to the nudix hydrolase family
BF37_1903	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF37_1905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF37_1906	COG0740	serine-type endopeptidase activity
BF37_1907	COG2323	membrane
BF37_191	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF37_1910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_1915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF37_1918	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF37_1920	COG0149	triose-phosphate isomerase activity
BF37_1921	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF37_1923	COG4974	Belongs to the 'phage' integrase family
BF37_1928	COG4695	Portal protein
BF37_194	COG3842	ATPase activity
BF37_1948	COG1346	cytolysis
BF37_1949	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF37_195	COG3842	ATPase activity
BF37_1950	COG1647	Serine aminopeptidase, S33
BF37_1951	COG0557	exoribonuclease II activity
BF37_1960	COG3223	Belongs to the PsiE family
BF37_1961	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_1964	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF37_1965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF37_1967	COG3290	protein histidine kinase activity
BF37_1967	COG0840	transmembrane signaling receptor activity
BF37_1969	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF37_197	COG1840	ABC-type Fe3 transport system, periplasmic component
BF37_1970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF37_1971	COG1252	NADH dehydrogenase
BF37_1973	COG1733	regulation of RNA biosynthetic process
BF37_1974	COG2814	Major facilitator Superfamily
BF37_1975	COG0656	L-ascorbic acid biosynthetic process
BF37_1980	COG2910	NAD(P)H-binding
BF37_1981	COG1115	amino acid carrier protein
BF37_1982	COG1115	amino acid carrier protein
BF37_1983	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_1984	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_1986	COG2311	Membrane
BF37_1989	COG1611	Belongs to the LOG family
BF37_1992	COG0783	Belongs to the Dps family
BF37_1993	COG1115	amino acid carrier protein
BF37_1994	COG0490	domain, Protein
BF37_1995	COG0475	glutathione-regulated potassium exporter activity
BF37_1998	COG1741	Belongs to the pirin family
BF37_1999	COG3227	Zinc metalloprotease (Elastase)
BF37_2	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF37_200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF37_2000	COG2151	metal-sulfur cluster biosynthetic enzyme
BF37_2003	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_2005	COG5002	protein histidine kinase activity
BF37_2006	COG0745	RESPONSE REGULATOR receiver
BF37_2007	COG1376	ErfK ybiS ycfS ynhG family protein
BF37_2009	COG0586	Pfam SNARE associated Golgi protein
BF37_2016	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_2018	COG0706	membrane insertase activity
BF37_202	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF37_2020	COG0531	amino acid
BF37_2021	COG2814	Major facilitator Superfamily
BF37_2025	COG0840	transmembrane signaling receptor activity
BF37_2026	COG0011	TIGRFAM Protein of
BF37_2029	COG1686	Belongs to the peptidase S11 family
BF37_203	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_2031	COG1024	Enoyl-CoA hydratase
BF37_2031	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF37_2032	COG0183	Belongs to the thiolase family
BF37_2033	COG1960	acyl-CoA dehydrogenase activity
BF37_2034	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_2035	COG1309	transcriptional regulator
BF37_2040	COG0039	L-malate dehydrogenase activity
BF37_2049	COG1393	Belongs to the ArsC family
BF37_2051	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF37_2052	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF37_2054	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF37_2055	COG2011	ABC-type metal ion transport system permease component
BF37_2056	COG1464	Belongs to the NlpA lipoprotein family
BF37_2057	COG1464	Belongs to the NlpA lipoprotein family
BF37_2058	COG0396	ATPase activity
BF37_2059	COG0719	Fe-S assembly protein
BF37_2060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF37_2061	COG0822	iron-sulfur transferase activity
BF37_2062	COG0719	Fe-S assembly protein
BF37_2064	COG1695	Transcriptional regulator
BF37_2065	COG0737	Belongs to the 5'-nucleotidase family
BF37_2066	COG3377	Domain of unknown function (DUF1805)
BF37_2068	COG0739	heme binding
BF37_207	COG2030	dehydratase
BF37_2073	COG4377	Putative membrane peptidase family (DUF2324)
BF37_2074	COG0789	Transcriptional regulator
BF37_2076	COG4470	Protein conserved in bacteria
BF37_2079	COG1494	fructose-1,6-bisphosphatase
BF37_2080	COG2445	Protein of unknown function DUF86
BF37_2082	COG0647	UMP catabolic process
BF37_2083	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF37_2085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF37_2086	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF37_2088	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF37_2089	COG4837	Protein of unknown function (DUF1462)
BF37_209	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF37_2097	COG2824	Alkylphosphonate utilization operon protein PhnA
BF37_2098	COG0390	transport system, permease component
BF37_21	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF37_210	COG0861	Integral membrane protein TerC family
BF37_2100	COG1252	NADH dehydrogenase
BF37_2103	COG0316	Belongs to the HesB IscA family
BF37_2106	COG1683	Conserved Protein
BF37_2109	COG3708	Transcriptional regulator
BF37_211	COG2116	formate transmembrane transporter activity
BF37_2112	COG1252	NADH dehydrogenase
BF37_2115	COG3584	3D domain protein
BF37_2118	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF37_2119	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF37_2121	COG1268	BioY protein
BF37_2123	COG2050	protein possibly involved in aromatic compounds catabolism
BF37_2124	COG0423	glycine-tRNA ligase activity
BF37_2127	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF37_2128	COG5018	Exonuclease
BF37_213	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF37_2132	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF37_2134	COG2267	carboxylic ester hydrolase activity
BF37_2135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF37_2136	COG1522	sequence-specific DNA binding
BF37_2137	COG0436	Aminotransferase
BF37_2138	COG1098	S1 RNA binding domain
BF37_2139	COG2155	Conserved Protein
BF37_2140	COG0166	Belongs to the GPI family
BF37_2141	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF37_2143	COG1285	pathogenesis
BF37_2151	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF37_217	COG2186	Transcriptional regulator
BF37_2170	COG0039	L-malate dehydrogenase activity
BF37_2172	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF37_2173	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF37_2174	COG0297	glycogen (starch) synthase activity
BF37_2175	COG0058	SHG alpha-glucan phosphorylase activity
BF37_2179	COG1278	Cold shock
BF37_218	COG5002	protein histidine kinase activity
BF37_2180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF37_2181	COG1575	Belongs to the MenA family. Type 1 subfamily
BF37_2182	COG1169	isochorismate synthase
BF37_2183	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF37_2184	COG0596	Alpha beta hydrolase
BF37_2185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF37_2187	COG4948	Mandelate Racemase Muconate Lactonizing
BF37_219	COG0745	RESPONSE REGULATOR receiver
BF37_2193	COG3964	amidohydrolase
BF37_22	COG4862	establishment of competence for transformation
BF37_2200	COG0577	efflux transmembrane transporter activity
BF37_2201	COG0577	efflux transmembrane transporter activity
BF37_2202	COG1136	(ABC) transporter
BF37_2203	COG0577	efflux transmembrane transporter activity
BF37_2204	COG0577	efflux transmembrane transporter activity
BF37_2206	COG0577	efflux transmembrane transporter activity
BF37_2207	COG2205	protein histidine kinase activity
BF37_2208	COG0745	RESPONSE REGULATOR receiver
BF37_2209	COG3708	Transcriptional regulator
BF37_2209	COG2207	Transcriptional regulator
BF37_221	COG3835	regulator
BF37_2210	COG1136	(ABC) transporter
BF37_2211	COG0577	efflux transmembrane transporter activity
BF37_2213	COG0586	Pfam SNARE associated Golgi protein
BF37_222	COG0277	FAD linked oxidase domain protein
BF37_2220	COG1597	lipid kinase activity
BF37_2226	COG0745	RESPONSE REGULATOR receiver
BF37_2227	COG5002	protein histidine kinase activity
BF37_223	COG0247	lactate metabolic process
BF37_2234	COG1842	Phage shock protein A
BF37_2239	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_224	COG2340	Cysteine-rich secretory protein family
BF37_2243	COG1294	oxidase, subunit
BF37_2244	COG1271	oxidase subunit
BF37_2246	COG0288	reversible hydration of carbon dioxide
BF37_2251	COG0494	nUDIX hydrolase
BF37_2253	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF37_2257	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF37_2258	COG1116	anion transmembrane transporter activity
BF37_2259	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF37_226	COG0564	pseudouridine synthase activity
BF37_2263	COG1368	sulfuric ester hydrolase activity
BF37_2264	COG2267	carboxylic ester hydrolase activity
BF37_2267	COG5002	protein histidine kinase activity
BF37_2268	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF37_2278	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF37_228	COG2409	Drug exporters of the RND superfamily
BF37_2280	COG0438	transferase activity, transferring glycosyl groups
BF37_2281	COG0671	phosphoesterase, PA-phosphatase related
BF37_2282	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF37_2283	COG2267	carboxylic ester hydrolase activity
BF37_2287	COG1794	racemase activity, acting on amino acids and derivatives
BF37_2289	COG1131	(ABC) transporter
BF37_2290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF37_2291	COG1242	4 iron, 4 sulfur cluster binding
BF37_2295	COG1136	(ABC) transporter
BF37_2297	COG0582	viral genome integration into host DNA
BF37_2298	COG0490	domain, Protein
BF37_2299	COG0475	glutathione-regulated potassium exporter activity
BF37_230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF37_2300	COG2814	Major facilitator Superfamily
BF37_2308	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF37_231	COG1177	transmembrane transport
BF37_2310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_2314	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF37_2315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF37_2317	COG0303	'Molybdopterin
BF37_2318	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF37_2319	COG0314	molybdopterin synthase activity
BF37_232	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF37_2322	COG4975	Glucose uptake
BF37_2324	COG1329	Transcriptional regulator
BF37_2328	COG3832	glyoxalase III activity
BF37_233	COG3842	ATPase activity
BF37_2330	COG2814	Major facilitator Superfamily
BF37_2331	COG2081	HI0933 family
BF37_2332	COG2244	polysaccharide biosynthetic process
BF37_2333	COG1187	pseudouridine synthase activity
BF37_2334	COG1349	DNA-binding transcription factor activity
BF37_2335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF37_2336	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF37_2338	COG1523	belongs to the glycosyl hydrolase 13 family
BF37_2339	COG0510	thiamine kinase activity
BF37_234	COG1012	belongs to the aldehyde dehydrogenase family
BF37_2342	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_2344	COG1363	Peptidase, m42
BF37_2345	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF37_2346	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF37_2347	COG4848	Belongs to the UPF0354 family
BF37_2348	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_2350	COG1674	ftsk spoiiie
BF37_2353	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_2357	COG2309	aminopeptidase activity
BF37_2359	COG3118	belongs to the thioredoxin family
BF37_2360	COG4851	CamS sex pheromone cAM373 precursor
BF37_2361	COG1609	Transcriptional regulator
BF37_2368	COG0666	response to abiotic stimulus
BF37_2370	COG0745	RESPONSE REGULATOR receiver
BF37_2372	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF37_2373	COG0517	IMP dehydrogenase activity
BF37_2374	COG0454	-acetyltransferase
BF37_2375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF37_2377	COG1595	DNA-templated transcription, initiation
BF37_2379	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF37_2383	COG0626	cystathionine gamma-synthase activity
BF37_2384	COG1956	GAF domain-containing protein
BF37_2385	COG1309	transcriptional regulator
BF37_2386	COG1309	transcriptional regulator
BF37_2387	COG0697	spore germination
BF37_2388	COG0583	DNA-binding transcription factor activity
BF37_2390	COG1104	cysteine desulfurase activity
BF37_2393	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF37_2395	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF37_2396	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF37_2398	COG3874	Sporulation protein YtfJ
BF37_2399	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF37_24	COG1408	metallophosphoesterase
BF37_240	COG0681	Belongs to the peptidase S26 family
BF37_2400	COG0827	DNA restriction-modification system
BF37_2401	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF37_2405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_241	COG1686	Belongs to the peptidase S11 family
BF37_2414	COG0589	response to stress
BF37_2415	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_2418	COG1476	TRANSCRIPTIONal
BF37_2420	COG0662	Cupin 2, conserved barrel domain protein
BF37_2421	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_2428	COG0006	proline dipeptidase activity
BF37_243	COG2226	methyltransferase
BF37_2431	COG4109	DRTGG domain
BF37_2435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF37_2438	COG0587	DNA-directed DNA polymerase activity
BF37_2439	COG0281	malic enzyme
BF37_2440	COG1725	Transcriptional regulator
BF37_2445	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF37_2446	COG0628	permease
BF37_2448	COG0372	Belongs to the citrate synthase family
BF37_2449	COG0538	isocitrate dehydrogenase activity
BF37_2453	COG0745	RESPONSE REGULATOR receiver
BF37_2454	COG5002	protein histidine kinase activity
BF37_2455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF37_2455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF37_2456	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF37_2457	COG1971	Probably functions as a manganese efflux pump
BF37_2458	COG0237	dephospho-CoA kinase activity
BF37_2459	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF37_2460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF37_2462	COG3611	Membrane attachment protein
BF37_2463	COG1484	DNA-dependent DNA replication
BF37_2465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF37_2466	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF37_2470	COG1363	Peptidase, m42
BF37_2471	COG1309	transcriptional regulator
BF37_2472	COG1566	PFAM secretion protein HlyD family protein
BF37_2473	COG2814	Major facilitator Superfamily
BF37_2478	COG1418	mRNA catabolic process
BF37_2480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF37_2482	COG0072	phenylalanine-tRNA ligase activity
BF37_2482	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_2483	COG0017	Asparaginyl-tRNA synthetase
BF37_2489	COG1286	toxin biosynthetic process
BF37_2490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF37_2490	COG1796	DNA polymerase
BF37_2493	COG1187	pseudouridine synthase activity
BF37_2494	COG1114	Component of the transport system for branched-chain amino acids
BF37_2495	COG5386	Cell surface protein
BF37_2497	COG5386	Cell surface protein
BF37_2500	COG1120	ATPase activity
BF37_2501	COG4509	Sortase family
BF37_2504	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF37_2505	COG4895	conserved protein (DUF2196)
BF37_2507	COG0745	RESPONSE REGULATOR receiver
BF37_2508	COG2205	protein histidine kinase activity
BF37_2509	COG1131	(ABC) transporter
BF37_2515	COG2318	DinB family
BF37_2519	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_2520	COG1309	transcriptional regulator
BF37_2521	COG1024	Enoyl-CoA hydratase
BF37_2522	COG2086	electron transfer activity
BF37_2523	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF37_2524	COG3118	belongs to the thioredoxin family
BF37_2526	COG1719	4-vinyl reductase, 4VR
BF37_2527	COG2009	succinate dehydrogenase
BF37_2528	COG1053	succinate dehydrogenase
BF37_2529	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF37_2530	COG0824	Thioesterase
BF37_2531	COG1876	peptidase activity
BF37_2532	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF37_2533	COG1360	Flagellar Motor Protein
BF37_2534	COG1360	Flagellar Motor Protein
BF37_2535	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF37_2536	COG4152	abc transporter atp-binding protein
BF37_2537	COG1668	transmembrane transport
BF37_2538	COG1959	2 iron, 2 sulfur cluster binding
BF37_254	COG1476	TRANSCRIPTIONal
BF37_2540	COG0697	spore germination
BF37_2541	COG1396	sequence-specific DNA binding
BF37_2542	COG1983	PspC domain protein
BF37_2545	COG3279	Response regulator of the LytR AlgR family
BF37_2546	COG3275	phosphorelay sensor kinase activity
BF37_2547	COG4608	Belongs to the ABC transporter superfamily
BF37_2548	COG0444	Belongs to the ABC transporter superfamily
BF37_2552	COG0402	S-adenosylhomocysteine deaminase activity
BF37_2553	COG0402	S-adenosylhomocysteine deaminase activity
BF37_2555	COG2233	PERMEase
BF37_2556	COG2197	response regulator
BF37_2559	COG1309	transcriptional regulator
BF37_256	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF37_2563	COG5401	PFAM Sporulation and spore germination
BF37_2565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF37_2566	COG0622	Phosphoesterase
BF37_2576	COG0470	DNA polymerase III
BF37_2576	COG1067	ATP-dependent peptidase activity
BF37_2579	COG1764	response to oxidative stress
BF37_2580	COG1846	Transcriptional regulator
BF37_2582	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF37_2584	COG1587	Uroporphyrinogen-III synthase
BF37_2585	COG0113	porphobilinogen synthase activity
BF37_2587	COG1388	LysM domain
BF37_2589	COG0525	valine-tRNA ligase activity
BF37_2590	COG0285	dihydrofolate synthase activity
BF37_2594	COG1077	Cell shape determining protein MreB Mrl
BF37_2595	COG1792	Involved in formation and maintenance of cell shape
BF37_2598	COG2894	cell division
BF37_2599	COG0739	heme binding
BF37_26	COG1266	CAAX protease self-immunity
BF37_2600	COG1994	Peptidase M50
BF37_2601	COG1530	ribonuclease E activity
BF37_2603	COG2868	ribosomal protein
BF37_2605	COG3290	protein histidine kinase activity
BF37_2606	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF37_2607	COG0745	RESPONSE REGULATOR receiver
BF37_2609	COG5002	protein histidine kinase activity
BF37_2610	COG1136	(ABC) transporter
BF37_2611	COG0577	efflux transmembrane transporter activity
BF37_2612	COG0577	efflux transmembrane transporter activity
BF37_2613	COG0077	Prephenate dehydratase
BF37_2614	COG2258	MOSC domain
BF37_2615	COG1827	regulation of RNA biosynthetic process
BF37_2616	COG1104	cysteine desulfurase activity
BF37_2617	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF37_2618	COG0157	Belongs to the NadC ModD family
BF37_2623	COG0640	Transcriptional regulator
BF37_2624	COG0697	spore germination
BF37_2625	COG0697	spore germination
BF37_2627	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF37_2633	COG1862	Preprotein translocase
BF37_2635	COG2323	membrane
BF37_2636	COG2244	polysaccharide biosynthetic process
BF37_2638	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF37_2638	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF37_2639	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF37_2640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF37_2640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF37_2642	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF37_2645	COG0124	histidyl-tRNA synthetase
BF37_2647	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF37_2649	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF37_2650	COG1959	2 iron, 2 sulfur cluster binding
BF37_2651	COG1104	cysteine desulfurase activity
BF37_2652	COG0482	sulfurtransferase activity
BF37_2654	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF37_2658	COG0628	permease
BF37_266	COG5634	Uncharacterized conserved protein (DUF2278)
BF37_2660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF37_2664	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF37_267	COG1620	l-lactate permease
BF37_2670	COG0768	penicillin binding
BF37_2675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF37_2676	COG0626	cystathionine gamma-synthase activity
BF37_2677	COG1454	alcohol dehydrogenase
BF37_2677	COG1012	belongs to the aldehyde dehydrogenase family
BF37_2679	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_2687	COG2259	Doxx family
BF37_2688	COG2514	catechol 2,3-dioxygenase activity
BF37_2689	COG2514	catechol 2,3-dioxygenase activity
BF37_2691	COG3186	Phenylalanine-4-hydroxylase
BF37_2692	COG1404	Belongs to the peptidase S8 family
BF37_2699	COG2267	carboxylic ester hydrolase activity
BF37_27	COG0514	ATP-dependent DNA helicase (RecQ)
BF37_2701	COG1785	Belongs to the alkaline phosphatase family
BF37_2703	COG2357	RelA SpoT domain protein
BF37_2704	COG0778	Nitroreductase
BF37_2706	COG1595	DNA-templated transcription, initiation
BF37_2709	COG1191	sigma factor activity
BF37_2711	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF37_2712	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF37_2714	COG1534	Rna-binding protein
BF37_2716	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF37_2717	COG0799	negative regulation of ribosome biogenesis
BF37_2718	COG2226	methyltransferase
BF37_2719	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF37_2720	COG1555	photosystem II stabilization
BF37_2720	COG1596	polysaccharide export
BF37_2721	COG2131	deaminase
BF37_2722	COG2333	competence protein COMEC
BF37_2722	COG0658	competence protein
BF37_2724	COG1466	dna polymerase III delta subunit
BF37_2729	COG1733	regulation of RNA biosynthetic process
BF37_2730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF37_2732	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF37_2736	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF37_2737	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF37_2739	COG1610	YqeY-like protein
BF37_274	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF37_274	COG0512	Glutamine amidotransferase of anthranilate synthase
BF37_2742	COG1702	phosphate starvation-inducible protein PhoH
BF37_2743	COG1480	7TM receptor with intracellular HD hydrolase
BF37_2745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF37_2746	COG0295	cytidine deaminase activity
BF37_2747	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF37_2750	COG0517	IMP dehydrogenase activity
BF37_2752	COG0358	DNA primase activity
BF37_2753	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF37_2754	COG2010	Cytochrome c
BF37_2755	COG2384	SAM-dependent methyltransferase
BF37_2756	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF37_276	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF37_2762	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_2763	COG1121	(ABC) transporter
BF37_2764	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF37_2765	COG0735	belongs to the Fur family
BF37_277	COG5492	domain, Protein
BF37_2770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF37_2771	COG0477	Major facilitator Superfamily
BF37_2773	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF37_2774	COG0573	inorganic phosphate transmembrane transporter activity
BF37_2775	COG0581	inorganic phosphate transmembrane transporter activity
BF37_2776	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF37_2777	COG0704	Plays a role in the regulation of phosphate uptake
BF37_2778	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF37_2780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF37_2781	COG4483	Protein conserved in bacteria
BF37_2782	COG1940	carbohydrate kinase activity
BF37_2784	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_2788	COG0626	cystathionine gamma-synthase activity
BF37_2789	COG0626	cystathionine gamma-synthase activity
BF37_2790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF37_2790	COG0646	methionine synthase
BF37_2791	COG0646	methionine synthase
BF37_2791	COG1410	methionine synthase
BF37_2792	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF37_28	COG4955	Helix-turn-helix domain
BF37_280	COG2382	esterase
BF37_2802	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF37_2803	COG1459	type II secretion system
BF37_2805	COG4970	Tfp pilus assembly protein FimT
BF37_281	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF37_2816	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF37_282	COG2153	protein acetylation
BF37_2822	COG1725	Transcriptional regulator
BF37_2823	COG1131	(ABC) transporter
BF37_2830	COG2076	Multidrug Resistance protein
BF37_2831	COG2076	Multidrug Resistance protein
BF37_2833	COG1609	Transcriptional regulator
BF37_2834	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_2835	COG0095	Lipoate-protein ligase
BF37_2840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF37_2841	COG3872	metal-dependent enzyme
BF37_2844	COG0006	proline dipeptidase activity
BF37_2849	COG3854	ATPases associated with a variety of cellular activities
BF37_2858	COG0511	ligase activity, forming carbon-carbon bonds
BF37_2859	COG0439	Biotin carboxylase
BF37_2860	COG1302	Protein conserved in bacteria
BF37_2865	COG0142	geranyltranstransferase activity
BF37_2867	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF37_2869	COG0497	DNA recombination
BF37_2870	COG0750	zinc metalloprotease
BF37_2871	COG0745	RESPONSE REGULATOR receiver
BF37_2873	COG3093	addiction module antidote protein HigA
BF37_2874	COG0584	glycerophosphoryl diester phosphodiesterase
BF37_2876	COG3290	protein histidine kinase activity
BF37_2876	COG3829	transcription factor binding
BF37_2877	COG0280	phosphate acetyltransferase
BF37_2878	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF37_2880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF37_2881	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF37_2882	COG0022	dehydrogenase e1 component
BF37_2883	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF37_2884	COG0772	Belongs to the SEDS family
BF37_2885	COG2816	NAD+ diphosphatase activity
BF37_2888	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF37_2889	COG0765	amino acid transport
BF37_2890	COG1126	abc transporter atp-binding protein
BF37_2891	COG4129	membrane
BF37_2892	COG1376	ErfK ybiS ycfS ynhG family protein
BF37_2894	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_2895	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF37_29	COG1141	Ferredoxin
BF37_290	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF37_2901	COG1760	l-serine dehydratase
BF37_2902	COG1760	l-serine dehydratase
BF37_2903	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF37_2905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_2906	COG0300	oxidoreductase activity
BF37_2909	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF37_2911	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF37_2915	COG1522	sequence-specific DNA binding
BF37_2917	COG0737	Belongs to the 5'-nucleotidase family
BF37_2920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF37_2922	COG0156	8-amino-7-oxononanoate synthase activity
BF37_2923	COG2226	methyltransferase
BF37_2923	COG1073	alpha beta
BF37_2924	COG4106	trans-aconitate 2-methyltransferase activity
BF37_2925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF37_2929	COG0307	riboflavin synthase, alpha
BF37_293	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF37_2930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF37_2930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF37_2933	COG1073	alpha beta
BF37_2934	COG0456	acetyltransferase
BF37_2935	COG1609	Transcriptional regulator
BF37_2936	COG2056	Na+-H+ antiporter family
BF37_2937	COG0596	Alpha beta hydrolase
BF37_2939	COG0737	Belongs to the 5'-nucleotidase family
BF37_2939	COG4085	toxin activity
BF37_2939	COG1525	nuclease
BF37_2941	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF37_2941	COG0456	acetyltransferase
BF37_2942	COG0656	L-ascorbic acid biosynthetic process
BF37_2943	COG0667	Aldo Keto reductase
BF37_2947	COG1300	Membrane
BF37_2948	COG0735	belongs to the Fur family
BF37_2950	COG4974	Belongs to the 'phage' integrase family
BF37_2955	COG0598	Magnesium transport protein CorA
BF37_2958	COG1846	Transcriptional regulator
BF37_2962	COG1131	(ABC) transporter
BF37_2963	COG1725	Transcriptional regulator
BF37_2964	COG1686	Belongs to the peptidase S11 family
BF37_2968	COG0733	neurotransmitter:sodium symporter activity
BF37_297	COG0463	Glycosyl transferase, family 2
BF37_297	COG0457	Tetratricopeptide repeat
BF37_2973	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_2976	COG0697	spore germination
BF37_2977	COG0561	phosphatase activity
BF37_2978	COG4086	secreted protein
BF37_2979	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF37_2980	COG0456	acetyltransferase
BF37_2981	COG1547	Domain of unknown function (DUF309)
BF37_2986	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF37_2990	COG3711	transcriptional antiterminator
BF37_2991	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_2991	COG2190	(PTS) system
BF37_2991	COG1263	PTS System
BF37_2996	COG0778	Nitroreductase
BF37_2997	COG3706	GGDEF domain
BF37_2998	COG2084	Dehydrogenase
BF37_2999	COG2084	Dehydrogenase
BF37_30	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF37_3002	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF37_3006	COG0436	Aminotransferase
BF37_3007	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF37_301	COG1216	Glycosyl transferase, family 2
BF37_3011	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3012	COG1695	Transcriptional regulator
BF37_3019	COG0183	Belongs to the thiolase family
BF37_302	COG0772	Belongs to the SEDS family
BF37_3027	COG3842	ATPase activity
BF37_3028	COG0366	Alpha amylase catalytic
BF37_303	COG0772	Belongs to the SEDS family
BF37_3030	COG2182	Extracellular solute-binding protein
BF37_3031	COG1175	transmembrane transport
BF37_3032	COG3833	ABC-type maltose transport systems, permease component
BF37_3033	COG1609	Transcriptional regulator
BF37_3034	COG0436	Aminotransferase
BF37_3036	COG2205	protein histidine kinase activity
BF37_3038	COG3209	COG3209 Rhs family protein
BF37_3042	COG2814	Major facilitator Superfamily
BF37_3049	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF37_3051	COG1408	metallophosphoesterase
BF37_3052	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3053	COG2200	EAL domain
BF37_3056	COG4703	Protein of unknown function (DUF1797)
BF37_3058	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF37_306	COG0564	pseudouridine synthase activity
BF37_3060	COG0517	IMP dehydrogenase activity
BF37_3061	COG0583	DNA-binding transcription factor activity
BF37_3065	COG0569	domain protein
BF37_3066	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF37_3068	COG0561	phosphatase activity
BF37_3069	COG0242	peptide deformylase activity
BF37_307	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF37_3071	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF37_3072	COG0022	dehydrogenase e1 component
BF37_3073	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF37_308	COG2357	RelA SpoT domain protein
BF37_3082	COG1982	Orn Lys Arg decarboxylase major
BF37_3086	COG0483	inositol monophosphate 1-phosphatase activity
BF37_3091	COG4896	Protein conserved in bacteria
BF37_3093	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF37_3094	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF37_3095	COG4838	Belongs to the UPF0358 family
BF37_3096	COG0772	Belongs to the SEDS family
BF37_3097	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF37_310	COG4116	CYTH
BF37_3104	COG3336	cytochrome c oxidase
BF37_3107	COG2340	Cysteine-rich secretory protein family
BF37_311	COG2346	COG2346, Truncated hemoglobins
BF37_3110	COG0406	alpha-ribazole phosphatase activity
BF37_3111	COG3679	Belongs to the UPF0342 family
BF37_3115	COG0742	ribosomal rna small subunit methyltransferase
BF37_3116	COG3314	Sporulation integral membrane protein YlbJ
BF37_3118	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF37_3119	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF37_3121	COG0582	viral genome integration into host DNA
BF37_3125	COG1396	sequence-specific DNA binding
BF37_3129	COG1396	sequence-specific DNA binding
BF37_3135	COG1484	DNA-dependent DNA replication
BF37_314	COG1164	Oligoendopeptidase f
BF37_3140	COG1191	sigma factor activity
BF37_3156	COG0582	viral genome integration into host DNA
BF37_316	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF37_3161	COG4626	Terminase
BF37_3161	COG1802	Transcriptional regulator
BF37_317	COG4862	establishment of competence for transformation
BF37_318	COG0861	Integral membrane protein TerC family
BF37_3180	COG4824	toxin secretion phage lysis holin
BF37_319	COG1393	Belongs to the ArsC family
BF37_3190	COG1399	metal-binding, possibly nucleic acid-binding protein
BF37_3194	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF37_3197	COG4839	cell division protein FtsL
BF37_3199	COG0768	penicillin binding
BF37_3200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF37_3203	COG0772	Belongs to the SEDS family
BF37_3204	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF37_3205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF37_3206	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF37_3207	COG0849	cell division
BF37_3208	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF37_321	COG4166	transmembrane transport
BF37_3210	COG1191	sigma factor activity
BF37_3211	COG1191	sigma factor activity
BF37_3212	COG1873	PFAM PRC-barrel domain
BF37_3214	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF37_3216	COG0762	integral membrane protein
BF37_3217	COG2302	S4 RNA-binding domain
BF37_3218	COG3599	regulation of cell shape
BF37_3219	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF37_322	COG0534	Mate efflux family protein
BF37_3222	COG0564	pseudouridine synthase activity
BF37_3227	COG0505	Belongs to the CarA family
BF37_323	COG4608	Belongs to the ABC transporter superfamily
BF37_3235	COG3069	C4-dicarboxylate transmembrane transporter activity
BF37_3238	COG0006	proline dipeptidase activity
BF37_324	COG0444	Belongs to the ABC transporter superfamily
BF37_3240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF37_3241	COG1561	YicC-like family, N-terminal region
BF37_3243	COG0194	GDP metabolic process
BF37_3245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF37_3246	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF37_3247	COG0242	peptide deformylase activity
BF37_3249	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF37_3249	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF37_325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF37_3251	COG0631	protein serine/threonine phosphatase activity
BF37_3252	COG2815	serine threonine protein kinase
BF37_3252	COG0515	serine threonine protein kinase
BF37_3253	COG1162	GTPase activity
BF37_3254	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF37_3255	COG1564	THIamine pyrophosphokinase
BF37_3257	COG1302	Protein conserved in bacteria
BF37_3258	COG1461	Dihydroxyacetone kinase
BF37_3259	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF37_326	COG0601	transmembrane transport
BF37_3262	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF37_3263	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3266	COG1196	nuclear chromosome segregation
BF37_3267	COG0552	protein localization to endoplasmic reticulum
BF37_3269	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF37_327	COG4166	transmembrane transport
BF37_3271	COG1837	Belongs to the UPF0109 family
BF37_3279	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF37_3281	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF37_3283	COG4974	Belongs to the 'phage' integrase family
BF37_3289	COG0528	UMP kinase activity
BF37_329	COG0180	Tryptophanyl-tRNA synthetase
BF37_3291	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF37_3292	COG4589	Belongs to the CDS family
BF37_3293	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF37_3294	COG0750	zinc metalloprotease
BF37_3298	COG0195	Participates in both transcription termination and antitermination
BF37_3299	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF37_33	COG2096	Adenosyltransferase
BF37_3300	COG1358	cellular component organization or biogenesis
BF37_3302	COG1550	Protein conserved in bacteria
BF37_3304	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF37_3305	COG0196	riboflavin kinase activity
BF37_3308	COG0726	polysaccharide deacetylase
BF37_3309	COG0612	Peptidase, M16
BF37_331	COG5504	Zn-dependent protease
BF37_3310	COG1873	PFAM PRC-barrel domain
BF37_3311	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF37_3312	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF37_3313	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF37_3314	COG0527	aspartate kinase activity
BF37_3316	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF37_3317	COG0740	serine-type endopeptidase activity
BF37_3319	COG1674	ftsk spoiiie
BF37_332	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF37_3320	COG2188	Transcriptional regulator
BF37_3326	COG0612	Peptidase, M16
BF37_3327	COG0612	Peptidase, M16
BF37_3328	COG0300	oxidoreductase activity
BF37_333	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_3331	COG1426	Protein conserved in bacteria
BF37_3332	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF37_3337	COG1692	metallophosphoesterase
BF37_3338	COG2359	stage V sporulation protein S
BF37_3340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF37_3340	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF37_3341	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF37_3342	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF37_3343	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF37_3352	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF37_3354	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF37_3355	COG1368	sulfuric ester hydrolase activity
BF37_3356	COG0562	UDP-galactopyranose mutase
BF37_3357	COG3773	Cell wall hydrolase
BF37_3358	COG1404	Belongs to the peptidase S8 family
BF37_336	COG2267	carboxylic ester hydrolase activity
BF37_3361	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF37_3362	COG0596	Alpha beta hydrolase
BF37_3362	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF37_3363	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_3364	COG1380	Effector of murein hydrolase LrgA
BF37_3369	COG5001	Diguanylate cyclase
BF37_3369	COG3300	MHYT domain
BF37_3370	COG0346	lactoylglutathione lyase activity
BF37_3371	COG2267	carboxylic ester hydrolase activity
BF37_3374	COG2364	Membrane
BF37_3376	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF37_3379	COG2169	Transcriptional regulator
BF37_338	COG0542	response to heat
BF37_3380	COG0708	Exodeoxyribonuclease III
BF37_3382	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_3383	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_3384	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_3385	COG1120	ATPase activity
BF37_3386	COG2819	hydrolase of the alpha beta superfamily
BF37_3388	COG1937	Protein conserved in bacteria
BF37_3389	COG2608	mercury ion transmembrane transporter activity
BF37_3390	COG2217	Heavy metal translocating P-type atpase
BF37_3391	COG2217	Heavy metal translocating P-type atpase
BF37_3393	COG2116	formate transmembrane transporter activity
BF37_3394	COG1408	metallophosphoesterase
BF37_3397	COG1113	amino acid transport
BF37_34	COG5002	protein histidine kinase activity
BF37_340	COG0561	phosphatase activity
BF37_3400	COG2322	membrane
BF37_3401	COG1979	alcohol dehydrogenase
BF37_3402	COG1979	alcohol dehydrogenase
BF37_3403	COG1349	DNA-binding transcription factor activity
BF37_3404	COG1105	Belongs to the carbohydrate kinase PfkB family
BF37_3405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF37_3405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF37_3405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF37_3406	COG1388	LysM domain
BF37_3406	COG3584	3D domain protein
BF37_3413	COG0464	growth
BF37_3414	COG2860	membrane
BF37_3415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF37_3416	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF37_3417	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF37_3418	COG0789	Transcriptional regulator
BF37_3419	COG0174	glutamine synthetase
BF37_3424	COG1396	sequence-specific DNA binding
BF37_343	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_3441	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF37_3449	COG1595	DNA-templated transcription, initiation
BF37_345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF37_347	COG2996	Protein conserved in bacteria
BF37_3481	COG4824	toxin secretion phage lysis holin
BF37_3482	COG1388	LysM domain
BF37_3482	COG3409	Peptidoglycan-binding domain 1 protein
BF37_3482	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF37_3490	COG1695	Transcriptional regulator
BF37_3494	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF37_3496	COG0737	Belongs to the 5'-nucleotidase family
BF37_3499	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF37_35	COG0745	RESPONSE REGULATOR receiver
BF37_3500	COG3639	organic phosphonate transmembrane transporter activity
BF37_3506	COG1132	(ABC) transporter
BF37_3507	COG1132	(ABC) transporter
BF37_3510	COG3409	Peptidoglycan-binding domain 1 protein
BF37_3510	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF37_3512	COG0730	response to heat
BF37_3515	COG1346	cytolysis
BF37_3516	COG1380	Effector of murein hydrolase LrgA
BF37_3517	COG0583	DNA-binding transcription factor activity
BF37_3519	COG0785	Cytochrome C biogenesis protein
BF37_352	COG0004	ammonium transporteR
BF37_3520	COG4846	Membrane protein involved in cytochrome C biogenesis
BF37_353	COG0753	catalase activity
BF37_3530	COG2226	methyltransferase
BF37_3535	COG0010	Belongs to the arginase family
BF37_3536	COG1329	Transcriptional regulator
BF37_3537	COG1902	pentaerythritol trinitrate reductase activity
BF37_3538	COG0069	glutamate synthase activity
BF37_3539	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF37_3540	COG0346	lactoylglutathione lyase activity
BF37_3541	COG0400	carboxylic ester hydrolase activity
BF37_3542	COG5002	protein histidine kinase activity
BF37_3544	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_355	COG0367	asparagine synthase
BF37_3553	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_3554	COG1268	BioY protein
BF37_3555	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_3556	COG0183	Belongs to the thiolase family
BF37_3559	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF37_3561	COG2211	Major facilitator Superfamily
BF37_3564	COG0726	polysaccharide deacetylase
BF37_3566	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF37_3567	COG2274	protein secretion by the type I secretion system
BF37_3569	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF37_3575	COG0824	Thioesterase
BF37_3576	COG4841	protein insertion into membrane
BF37_3577	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF37_3580	COG0745	RESPONSE REGULATOR receiver
BF37_3581	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF37_3582	COG1832	CoA-binding protein
BF37_3583	COG0187	DNA topoisomerase II activity
BF37_3584	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF37_3585	COG0673	inositol 2-dehydrogenase activity
BF37_3587	COG1131	(ABC) transporter
BF37_3591	COG1595	DNA-templated transcription, initiation
BF37_3593	COG1316	TRANSCRIPTIONal
BF37_3594	COG1301	dicarboxylic acid transport
BF37_3595	COG4166	transmembrane transport
BF37_3596	COG4166	transmembrane transport
BF37_3597	COG4166	transmembrane transport
BF37_3598	COG2226	methyltransferase
BF37_36	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF37_360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF37_3607	COG0697	spore germination
BF37_3609	COG3383	formate dehydrogenase (NAD+) activity
BF37_3610	COG2427	Protein of unknown function (DUF1641)
BF37_3611	COG5609	conserved protein (DUF2294)
BF37_3612	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF37_3614	COG2116	formate transmembrane transporter activity
BF37_3615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF37_3616	COG0303	'Molybdopterin
BF37_3617	COG0314	molybdopterin synthase activity
BF37_3619	COG0489	protein tyrosine kinase activity
BF37_3622	COG3326	Membrane
BF37_3623	COG2962	Rard protein
BF37_3624	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF37_3625	COG1657	PFAM Prenyltransferase squalene oxidase
BF37_3627	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3628	COG1012	belongs to the aldehyde dehydrogenase family
BF37_3629	COG3924	membrane
BF37_3630	COG4145	pantothenate transmembrane transporter activity
BF37_3633	COG0165	Argininosuccinate lyase
BF37_3636	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3642	COG0716	FMN binding
BF37_3644	COG1278	Cold shock
BF37_3650	COG2720	vancomycin resistance protein
BF37_3651	COG2514	catechol 2,3-dioxygenase activity
BF37_3653	COG1285	pathogenesis
BF37_3655	COG1024	Enoyl-CoA hydratase
BF37_3656	COG1216	Glycosyl transferase, family 2
BF37_3662	COG0277	FAD linked oxidase domain protein
BF37_3663	COG0385	Bile acid
BF37_3665	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF37_3666	COG2808	Putative FMN-binding domain
BF37_3669	COG0457	Tetratricopeptide repeat
BF37_3671	COG0604	alcohol dehydrogenase
BF37_3672	COG0640	Transcriptional regulator
BF37_3676	COG0584	glycerophosphoryl diester phosphodiesterase
BF37_368	COG1074	ATP-dependent DNA helicase activity
BF37_3682	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF37_3683	COG1164	Oligoendopeptidase f
BF37_3684	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF37_3687	COG1193	negative regulation of DNA recombination
BF37_369	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF37_3691	COG0583	DNA-binding transcription factor activity
BF37_3697	COG0384	phenazine biosynthesis protein PhzF
BF37_3698	COG3739	integral membrane protein
BF37_3699	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_37	COG1333	cytochrome c biogenesis protein
BF37_3700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_3702	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_3706	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF37_3707	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF37_371	COG0398	Pfam SNARE associated Golgi protein
BF37_3713	COG2814	Major facilitator Superfamily
BF37_3714	COG1113	amino acid transport
BF37_3715	COG0604	alcohol dehydrogenase
BF37_372	COG4903	ComK protein
BF37_3722	COG2072	flavoprotein involved in K transport
BF37_3729	COG3409	Peptidoglycan-binding domain 1 protein
BF37_3729	COG3757	hydrolase, family 25
BF37_3730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_3733	COG1151	hydroxylamine reductase activity
BF37_3738	COG3152	Membrane
BF37_3742	COG1309	transcriptional regulator
BF37_3745	COG1191	sigma factor activity
BF37_3748	COG0726	polysaccharide deacetylase
BF37_375	COG1278	Cold shock
BF37_3752	COG1733	regulation of RNA biosynthetic process
BF37_3753	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF37_3755	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_3757	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3759	COG0384	phenazine biosynthesis protein PhzF
BF37_3763	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_3766	COG1733	regulation of RNA biosynthetic process
BF37_3767	COG1733	regulation of RNA biosynthetic process
BF37_3768	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF37_377	COG2224	Isocitrate lyase
BF37_3770	COG0673	inositol 2-dehydrogenase activity
BF37_3771	COG2188	Transcriptional regulator
BF37_3772	COG1733	regulation of RNA biosynthetic process
BF37_3779	COG0814	amino acid
BF37_378	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF37_3780	COG0346	lactoylglutathione lyase activity
BF37_3783	COG2814	Major facilitator Superfamily
BF37_3784	COG0656	L-ascorbic acid biosynthetic process
BF37_3789	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_379	COG0497	DNA recombination
BF37_3792	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF37_3793	COG0604	alcohol dehydrogenase
BF37_3794	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF37_3795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF37_3797	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF37_3798	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF37_3800	COG1070	Carbohydrate kinase
BF37_3801	COG2706	6-phosphogluconolactonase activity
BF37_3802	COG3813	Protein conserved in bacteria
BF37_3803	COG1357	PFAM Pentapeptide repeats (8 copies)
BF37_3804	COG0697	spore germination
BF37_3805	COG0789	Transcriptional regulator
BF37_3806	COG1253	flavin adenine dinucleotide binding
BF37_3812	COG0477	Major facilitator Superfamily
BF37_3814	COG2226	methyltransferase
BF37_3818	COG0628	permease
BF37_3819	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF37_382	COG0697	spore germination
BF37_3820	COG0180	Tryptophanyl-tRNA synthetase
BF37_3822	COG1136	(ABC) transporter
BF37_3824	COG0110	maltose O-acetyltransferase activity
BF37_3825	COG0738	Major facilitator superfamily
BF37_3826	COG1940	carbohydrate kinase activity
BF37_3827	COG0346	lactoylglutathione lyase activity
BF37_3834	COG1011	Hydrolase
BF37_3839	COG1131	(ABC) transporter
BF37_3841	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_3845	COG0778	Nitroreductase
BF37_3846	COG1733	regulation of RNA biosynthetic process
BF37_3849	COG0124	histidyl-tRNA synthetase
BF37_385	COG0501	Belongs to the peptidase M48B family
BF37_3850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF37_3851	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF37_3852	COG3620	sequence-specific DNA binding
BF37_3855	COG2356	endonuclease I
BF37_3856	COG1288	antiporter activity
BF37_3857	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF37_3860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF37_3861	COG1122	ATPase activity
BF37_3867	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF37_3869	COG2031	fatty acid transporter
BF37_3871	COG1309	transcriptional regulator
BF37_3872	COG2076	Multidrug Resistance protein
BF37_3876	COG1131	(ABC) transporter
BF37_3877	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF37_3880	COG2814	Major facilitator Superfamily
BF37_3881	COG1846	Transcriptional regulator
BF37_3883	COG0477	Major facilitator Superfamily
BF37_3894	COG2207	Transcriptional regulator
BF37_3894	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_3895	COG0662	Cupin 2, conserved barrel domain protein
BF37_3898	COG1595	DNA-templated transcription, initiation
BF37_39	COG1187	pseudouridine synthase activity
BF37_390	COG0745	RESPONSE REGULATOR receiver
BF37_3902	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF37_3905	COG0531	amino acid
BF37_3906	COG1522	sequence-specific DNA binding
BF37_3907	COG1335	isochorismatase
BF37_3909	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF37_391	COG2205	protein histidine kinase activity
BF37_3910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF37_3911	COG1760	l-serine dehydratase
BF37_3912	COG1760	l-serine dehydratase
BF37_3913	COG0814	amino acid
BF37_3916	COG1309	transcriptional regulator
BF37_3917	COG2814	Major facilitator Superfamily
BF37_3918	COG2184	nucleotidyltransferase activity
BF37_3921	COG0534	Mate efflux family protein
BF37_3928	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF37_3932	COG0457	Tetratricopeptide repeat
BF37_3933	COG1609	Transcriptional regulator
BF37_3934	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF37_3935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF37_3936	COG0561	phosphatase activity
BF37_3937	COG0673	inositol 2-dehydrogenase activity
BF37_3938	COG0738	Major facilitator superfamily
BF37_394	COG2207	Transcriptional regulator
BF37_394	COG3708	Transcriptional regulator
BF37_3942	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF37_3944	COG0583	DNA-binding transcription factor activity
BF37_3946	COG1139	Iron-sulfur cluster binding protein
BF37_3947	COG1556	Lactate utilization protein
BF37_3948	COG2271	Major facilitator Superfamily
BF37_3949	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_395	COG1595	DNA-templated transcription, initiation
BF37_3950	COG2808	Putative FMN-binding domain
BF37_3951	COG0456	acetyltransferase
BF37_3952	COG1846	Transcriptional regulator
BF37_3953	COG2364	Membrane
BF37_3955	COG5002	protein histidine kinase activity
BF37_3955	COG3850	Histidine kinase
BF37_3958	COG0577	efflux transmembrane transporter activity
BF37_3959	COG1136	(ABC) transporter
BF37_3962	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF37_3963	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_3965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF37_3966	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_3969	COG1476	TRANSCRIPTIONal
BF37_397	COG1078	dGTPase activity
BF37_3975	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF37_398	COG1408	metallophosphoesterase
BF37_3980	COG5002	protein histidine kinase activity
BF37_3980	COG3850	Histidine kinase
BF37_3981	COG0745	RESPONSE REGULATOR receiver
BF37_3986	COG2814	Major facilitator Superfamily
BF37_3998	COG0346	lactoylglutathione lyase activity
BF37_40	COG0700	Nucleoside recognition
BF37_4001	COG1522	sequence-specific DNA binding
BF37_4004	COG0443	Heat shock 70 kDa protein
BF37_4009	COG0640	Transcriptional regulator
BF37_4010	COG0346	lactoylglutathione lyase activity
BF37_4011	COG0798	PFAM Bile acid sodium symporter
BF37_4017	COG1121	(ABC) transporter
BF37_4018	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF37_4019	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF37_4020	COG2267	carboxylic ester hydrolase activity
BF37_4021	COG1575	Belongs to the MenA family. Type 1 subfamily
BF37_4023	COG5609	conserved protein (DUF2294)
BF37_4024	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF37_4026	COG0288	reversible hydration of carbon dioxide
BF37_4027	COG0415	Belongs to the DNA photolyase family
BF37_4034	COG0598	Magnesium transport protein CorA
BF37_4035	COG0598	Magnesium transport protein CorA
BF37_4036	COG1846	Transcriptional regulator
BF37_4037	COG0583	DNA-binding transcription factor activity
BF37_4042	COG1335	isochorismatase
BF37_4043	COG2267	carboxylic ester hydrolase activity
BF37_4044	COG0753	catalase activity
BF37_4045	COG0737	Belongs to the 5'-nucleotidase family
BF37_405	COG3209	COG3209 Rhs family protein
BF37_4051	COG1115	amino acid carrier protein
BF37_4053	COG2066	Belongs to the glutaminase family
BF37_4054	COG4191	Histidine kinase
BF37_4055	COG4191	Histidine kinase
BF37_4056	COG0784	Response regulator, receiver
BF37_4057	COG0697	spore germination
BF37_4058	COG0531	amino acid
BF37_4063	COG0281	malic enzyme
BF37_4065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF37_4066	COG1114	Component of the transport system for branched-chain amino acids
BF37_4067	COG0531	amino acid
BF37_4068	COG0322	excinuclease ABC activity
BF37_4070	COG1396	sequence-specific DNA binding
BF37_4071	COG0252	asparaginase activity
BF37_4072	COG1027	Aspartate ammonia-lyase
BF37_4075	COG1063	alcohol dehydrogenase
BF37_4081	COG1113	amino acid transport
BF37_4082	COG1113	amino acid transport
BF37_4083	COG1280	lysine exporter protein (LysE YggA)
BF37_4084	COG3403	YqcI/YcgG family
BF37_4086	COG5577	PFAM Coat F domain
BF37_4089	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_4090	COG0574	Belongs to the PEP-utilizing enzyme family
BF37_4090	COG3848	Pyruvate phosphate dikinase
BF37_4093	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF37_41	COG2715	membrane protein required for spore maturation
BF37_4100	COG1960	acyl-CoA dehydrogenase activity
BF37_4102	COG0640	Transcriptional regulator
BF37_4103	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF37_4106	COG1414	Transcriptional regulator
BF37_4107	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF37_4108	COG1984	allophanate hydrolase subunit 2
BF37_411	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_4114	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF37_4124	COG4335	DNA alkylation repair
BF37_4126	COG0833	amino acid
BF37_4128	COG0730	response to heat
BF37_413	COG0095	Lipoate-protein ligase
BF37_4134	COG0596	Alpha beta hydrolase
BF37_4135	COG0745	RESPONSE REGULATOR receiver
BF37_4136	COG0642	Histidine kinase
BF37_414	COG1234	tRNA 3'-trailer cleavage
BF37_4140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_4144	COG0456	acetyltransferase
BF37_4145	COG2207	Transcriptional regulator
BF37_4150	COG0577	efflux transmembrane transporter activity
BF37_4150	COG1136	(ABC) transporter
BF37_4152	COG1725	Transcriptional regulator
BF37_4159	COG1846	Transcriptional regulator
BF37_416	COG1609	Transcriptional regulator
BF37_4160	COG0778	Nitroreductase
BF37_4162	COG0714	Associated with various cellular activities
BF37_4168	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF37_4170	COG0753	catalase activity
BF37_4171	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF37_4173	COG0463	Glycosyl transferase, family 2
BF37_4178	COG0463	Glycosyl transferase, family 2
BF37_4183	COG0714	Associated with various cellular activities
BF37_4187	COG0346	lactoylglutathione lyase activity
BF37_4188	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_4190	COG3279	Response regulator of the LytR AlgR family
BF37_4192	COG4377	Putative membrane peptidase family (DUF2324)
BF37_4195	COG3655	Transcriptional regulator
BF37_4197	COG1785	Belongs to the alkaline phosphatase family
BF37_4198	COG3239	Fatty acid desaturase
BF37_4199	COG1690	Belongs to the RtcB family
BF37_42	COG1686	Belongs to the peptidase S11 family
BF37_4200	COG0833	amino acid
BF37_4201	COG1414	Transcriptional regulator
BF37_4202	COG4187	Peptidase family M20/M25/M40
BF37_4203	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF37_4204	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF37_4206	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_421	COG1511	domain protein
BF37_4210	COG2329	Antibiotic biosynthesis monooxygenase
BF37_4217	COG1070	Carbohydrate kinase
BF37_4218	COG2390	Transcriptional regulator
BF37_422	COG1309	transcriptional regulator
BF37_4220	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF37_4222	COG1879	ABC-type sugar transport system periplasmic component
BF37_4228	COG1595	DNA-templated transcription, initiation
BF37_4230	COG1388	LysM domain
BF37_4230	COG3584	3D domain protein
BF37_4238	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF37_4238	COG1605	Chorismate mutase
BF37_4239	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF37_4240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF37_4241	COG0287	Prephenate dehydrogenase
BF37_4244	COG1309	transcriptional regulator
BF37_4245	COG2409	Drug exporters of the RND superfamily
BF37_4245	COG1033	growth of symbiont in host cell
BF37_4246	COG1033	growth of symbiont in host cell
BF37_4246	COG2409	Drug exporters of the RND superfamily
BF37_4248	COG0488	(ABC) transporter
BF37_4249	COG1368	sulfuric ester hydrolase activity
BF37_4250	COG0861	Integral membrane protein TerC family
BF37_4252	COG0726	polysaccharide deacetylase
BF37_4254	COG4912	Dna alkylation repair
BF37_4258	COG2318	DinB family
BF37_4259	COG0697	spore germination
BF37_4264	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF37_4272	COG1116	anion transmembrane transporter activity
BF37_4273	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF37_4274	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF37_4275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF37_4277	COG0628	permease
BF37_4286	COG1131	(ABC) transporter
BF37_4290	COG5146	pantothenate kinase activity
BF37_4291	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF37_4292	COG0436	Aminotransferase
BF37_4299	COG2226	methyltransferase
BF37_43	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF37_4302	COG2261	transglycosylase associated protein
BF37_4306	COG0477	Major facilitator Superfamily
BF37_4306	COG2814	Major facilitator Superfamily
BF37_4307	COG4533	DNA binding
BF37_4308	COG0789	Transcriptional regulator
BF37_4309	COG1664	Polymer-forming cytoskeletal
BF37_431	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF37_4311	COG2814	Major facilitator Superfamily
BF37_4315	COG1307	EDD domain protein, DegV family
BF37_4318	COG1164	Oligoendopeptidase f
BF37_432	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF37_4325	COG0745	RESPONSE REGULATOR receiver
BF37_4326	COG5002	protein histidine kinase activity
BF37_4327	COG2936	dipeptidyl-peptidase activity
BF37_433	COG2329	Antibiotic biosynthesis monooxygenase
BF37_4335	COG4948	Mandelate Racemase Muconate Lactonizing
BF37_4337	COG4166	transmembrane transport
BF37_4338	COG0519	Catalyzes the synthesis of GMP from XMP
BF37_4339	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF37_434	COG3428	Bacterial PH domain
BF37_4342	COG0586	Pfam SNARE associated Golgi protein
BF37_4349	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF37_435	COG3402	PFAM membrane-flanked domain
BF37_4350	COG3938	Belongs to the proline racemase family
BF37_4352	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF37_4353	COG1012	belongs to the aldehyde dehydrogenase family
BF37_4354	COG1115	amino acid carrier protein
BF37_4355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF37_4357	COG3397	chitin binding
BF37_4362	COG4637	Psort location Cytoplasmic, score
BF37_4365	COG0514	ATP-dependent DNA helicase (RecQ)
BF37_4366	COG2105	PFAM AIG2 family protein
BF37_4369	COG3973	AAA domain
BF37_4379	COG0658	competence protein
BF37_4379	COG2333	competence protein COMEC
BF37_4384	COG2205	protein histidine kinase activity
BF37_4388	COG3397	chitin binding
BF37_4389	COG2153	protein acetylation
BF37_4390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF37_4393	COG0740	serine-type endopeptidase activity
BF37_4395	COG0517	IMP dehydrogenase activity
BF37_4395	COG4175	Glycine betaine
BF37_4396	COG4176	ABC-type proline glycine betaine transport system permease component
BF37_4402	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF37_4402	COG0456	acetyltransferase
BF37_4403	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_4405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF37_4406	COG0022	dehydrogenase e1 component
BF37_4407	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF37_4408	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF37_4412	COG1959	2 iron, 2 sulfur cluster binding
BF37_4416	COG1349	DNA-binding transcription factor activity
BF37_4420	COG3284	Transcriptional regulator
BF37_4426	COG1309	transcriptional regulator
BF37_4427	COG3844	kynureninase activity
BF37_4428	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF37_4429	COG3483	tryptophan 2,3-dioxygenase activity
BF37_4432	COG3773	Cell wall hydrolase
BF37_4432	COG3409	Peptidoglycan-binding domain 1 protein
BF37_4433	COG2959	enzyme of heme biosynthesis
BF37_4436	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_4437	COG4129	membrane
BF37_444	COG3428	Bacterial PH domain
BF37_4443	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_4444	COG0697	spore germination
BF37_4446	COG0201	protein transport
BF37_4450	COG3227	Zinc metalloprotease (Elastase)
BF37_4455	COG0076	glutamate decarboxylase activity
BF37_446	COG3402	PFAM membrane-flanked domain
BF37_4460	COG1011	Hydrolase
BF37_4465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF37_4473	COG0322	excinuclease ABC activity
BF37_4476	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF37_448	COG1309	transcriptional regulator
BF37_4481	COG4667	esterase of the alpha-beta hydrolase superfamily
BF37_4487	COG3878	Protein conserved in bacteria
BF37_4494	COG1051	belongs to the nudix hydrolase family
BF37_4495	COG0592	DNA-directed DNA polymerase activity
BF37_4496	COG2816	NAD+ diphosphatase activity
BF37_4498	COG2223	nitrite transmembrane transporter activity
BF37_4505	COG0697	spore germination
BF37_4506	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_4507	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_451	COG4473	ABC transporter
BF37_4510	COG0584	glycerophosphoryl diester phosphodiesterase
BF37_4514	COG2814	Major facilitator Superfamily
BF37_4519	COG0693	protein deglycase activity
BF37_452	COG1131	(ABC) transporter
BF37_4525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF37_453	COG0537	adenosine 5'-monophosphoramidase activity
BF37_4532	COG2205	protein histidine kinase activity
BF37_4535	COG1122	ATPase activity
BF37_4537	COG1794	racemase activity, acting on amino acids and derivatives
BF37_4538	COG1819	glycosyl
BF37_454	COG4980	gas vesicle protein
BF37_4540	COG5002	protein histidine kinase activity
BF37_4542	COG0561	phosphatase activity
BF37_4549	COG2124	cytochrome p450
BF37_4566	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF37_4568	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_4569	COG0460	homoserine dehydrogenase
BF37_4573	COG0577	efflux transmembrane transporter activity
BF37_4574	COG0577	efflux transmembrane transporter activity
BF37_4575	COG1136	(ABC) transporter
BF37_458	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF37_4580	COG2205	protein histidine kinase activity
BF37_4582	COG0745	RESPONSE REGULATOR receiver
BF37_4584	COG3773	Cell wall hydrolase
BF37_4587	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF37_4588	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF37_459	COG3973	AAA domain
BF37_4591	COG1063	alcohol dehydrogenase
BF37_4593	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_4597	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF37_46	COG0392	lysyltransferase activity
BF37_46	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF37_4601	COG2814	Major facilitator Superfamily
BF37_4603	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF37_4606	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF37_4606	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF37_461	COG0477	Major facilitator Superfamily
BF37_4611	COG3227	Zinc metalloprotease (Elastase)
BF37_4615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF37_462	COG0477	Major facilitator Superfamily
BF37_4620	COG1686	Belongs to the peptidase S11 family
BF37_4621	COG2318	DinB family
BF37_4623	COG0572	uridine kinase
BF37_4624	COG1247	-acetyltransferase
BF37_4626	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF37_4627	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF37_4628	COG1024	Enoyl-CoA hydratase
BF37_4629	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF37_4630	COG0511	ligase activity, forming carbon-carbon bonds
BF37_4631	COG0439	Biotin carboxylase
BF37_4632	COG1960	acyl-CoA dehydrogenase activity
BF37_4637	COG1131	(ABC) transporter
BF37_4640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_4641	COG1252	NADH dehydrogenase
BF37_4643	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_4647	COG1309	transcriptional regulator
BF37_4652	COG1876	peptidase activity
BF37_4655	COG1476	TRANSCRIPTIONal
BF37_4656	COG0457	Tetratricopeptide repeat
BF37_4658	COG0737	Belongs to the 5'-nucleotidase family
BF37_4659	COG0737	Belongs to the 5'-nucleotidase family
BF37_4663	COG3718	enzyme involved in inositol metabolism
BF37_4667	COG1012	belongs to the aldehyde dehydrogenase family
BF37_4669	COG0673	inositol 2-dehydrogenase activity
BF37_4670	COG2814	Major facilitator Superfamily
BF37_4671	COG1609	Transcriptional regulator
BF37_4672	COG0671	phosphoesterase, PA-phosphatase related
BF37_4673	COG2367	Beta-lactamase
BF37_4676	COG0768	penicillin binding
BF37_4678	COG1595	DNA-templated transcription, initiation
BF37_4682	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF37_4688	COG1846	Transcriptional regulator
BF37_4689	COG3961	Belongs to the TPP enzyme family
BF37_4690	COG2226	methyltransferase
BF37_4692	COG0500	methyltransferase
BF37_4692	COG3615	Tellurite resistance protein tehB
BF37_4693	COG1136	(ABC) transporter
BF37_4693	COG0577	efflux transmembrane transporter activity
BF37_4696	COG1309	transcriptional regulator
BF37_470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF37_4701	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_4704	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF37_4705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF37_4706	COG2971	BadF BadG BcrA BcrD
BF37_4711	COG1649	PFAM Uncharacterised BCR, COG1649
BF37_4716	COG1595	DNA-templated transcription, initiation
BF37_472	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF37_4721	COG1396	sequence-specific DNA binding
BF37_4725	COG1132	(ABC) transporter
BF37_4726	COG1132	(ABC) transporter
BF37_4729	COG2258	MOSC domain
BF37_473	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF37_4730	COG0583	DNA-binding transcription factor activity
BF37_4733	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF37_4734	COG0583	DNA-binding transcription factor activity
BF37_4742	COG0561	phosphatase activity
BF37_4743	COG0010	Belongs to the arginase family
BF37_4746	COG1278	Cold shock
BF37_4748	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_4756	COG1247	-acetyltransferase
BF37_4763	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_477	COG2267	carboxylic ester hydrolase activity
BF37_4772	COG2226	methyltransferase
BF37_4777	COG2814	Major facilitator Superfamily
BF37_4778	COG0596	Alpha beta hydrolase
BF37_4782	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF37_4783	COG1187	pseudouridine synthase activity
BF37_4784	COG2329	Antibiotic biosynthesis monooxygenase
BF37_4787	COG1115	amino acid carrier protein
BF37_4789	COG2318	DinB family
BF37_479	COG0457	Tetratricopeptide repeat
BF37_4791	COG0776	regulation of translation
BF37_4794	COG2814	Major facilitator Superfamily
BF37_4795	COG3251	PFAM MbtH domain protein
BF37_4796	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF37_4797	COG3433	isochorismatase activity
BF37_4797	COG1535	isochorismatase
BF37_4798	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF37_4799	COG1169	isochorismate synthase
BF37_480	COG0346	lactoylglutathione lyase activity
BF37_4800	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_4801	COG2223	nitrite transmembrane transporter activity
BF37_4805	COG0419	ATPase involved in DNA repair
BF37_4806	COG0420	3'-5' exonuclease activity
BF37_4809	COG1024	Enoyl-CoA hydratase
BF37_481	COG0346	lactoylglutathione lyase activity
BF37_4810	COG1280	lysine exporter protein (LysE YggA)
BF37_4811	COG1012	belongs to the aldehyde dehydrogenase family
BF37_4812	COG2084	Dehydrogenase
BF37_4813	COG1960	acyl-CoA dehydrogenase activity
BF37_4814	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF37_4815	COG2079	MmgE PrpD family protein
BF37_4816	COG0372	Belongs to the citrate synthase family
BF37_4817	COG4841	protein insertion into membrane
BF37_4818	COG2814	Major facilitator Superfamily
BF37_4819	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF37_4819	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF37_482	COG2814	Major facilitator Superfamily
BF37_4827	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF37_483	COG1309	transcriptional regulator
BF37_4843	COG1787	Restriction endonuclease
BF37_4843	COG1715	Restriction endonuclease
BF37_4848	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF37_4849	COG0671	phosphoesterase, PA-phosphatase related
BF37_4850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF37_4851	COG4326	sporulation control protein
BF37_4859	COG1509	lysine 2,3-aminomutase activity
BF37_4860	COG3829	transcription factor binding
BF37_4861	COG0456	acetyltransferase
BF37_4862	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF37_4863	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF37_4864	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF37_4865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF37_4868	COG5506	Protein of unknown function (DUF1694)
BF37_4869	COG1012	belongs to the aldehyde dehydrogenase family
BF37_487	COG4717	serine-type aminopeptidase activity
BF37_4870	COG1253	flavin adenine dinucleotide binding
BF37_4877	COG1174	glycine betaine transport
BF37_4878	COG1125	glycine betaine transport
BF37_4878	COG0517	IMP dehydrogenase activity
BF37_488	COG0420	3'-5' exonuclease activity
BF37_4885	COG1070	Carbohydrate kinase
BF37_4893	COG1064	alcohol dehydrogenase
BF37_4894	COG1737	Transcriptional regulator
BF37_4896	COG2197	response regulator
BF37_4897	COG4585	Histidine kinase
BF37_4897	COG2203	Gaf domain
BF37_4898	COG0668	transmembrane transport
BF37_4900	COG1051	belongs to the nudix hydrolase family
BF37_4901	COG1335	isochorismatase
BF37_4905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF37_4906	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_4910	COG0367	asparagine synthase
BF37_4911	COG0071	Belongs to the small heat shock protein (HSP20) family
BF37_4912	COG1999	signal sequence binding
BF37_4913	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF37_4914	COG1307	EDD domain protein, DegV family
BF37_4916	COG0805	protein transport
BF37_4918	COG1272	protein, Hemolysin III
BF37_4919	COG0204	Acyl-transferase
BF37_4920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF37_4921	COG0768	penicillin binding
BF37_4924	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF37_4928	COG0546	phosphoglycolate phosphatase activity
BF37_4930	COG4473	ABC transporter
BF37_4931	COG1131	(ABC) transporter
BF37_4933	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF37_4935	COG0456	acetyltransferase
BF37_4937	COG1794	racemase activity, acting on amino acids and derivatives
BF37_4938	COG1454	alcohol dehydrogenase
BF37_4939	COG2610	gluconate transmembrane transporter activity
BF37_494	COG0393	Putative heavy-metal-binding
BF37_4944	COG0733	neurotransmitter:sodium symporter activity
BF37_4947	COG3850	Histidine kinase
BF37_4947	COG5002	protein histidine kinase activity
BF37_4948	COG0745	RESPONSE REGULATOR receiver
BF37_4949	COG0471	metal ion transport
BF37_4950	COG1929	Belongs to the glycerate kinase type-1 family
BF37_4968	COG1674	ftsk spoiiie
BF37_4972	COG0017	Asparaginyl-tRNA synthetase
BF37_4973	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF37_4976	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF37_4982	COG0018	arginyl-trna synthetase
BF37_4983	COG2521	methyltransferase
BF37_4983	COG2136	Putative SAM-dependent methyltransferase
BF37_4986	COG1413	lyase activity
BF37_4987	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF37_499	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF37_499	COG2198	Histidine kinase
BF37_499	COG2205	protein histidine kinase activity
BF37_499	COG0784	Response regulator, receiver
BF37_4990	COG0629	single-stranded DNA binding
BF37_4993	COG0488	(ABC) transporter
BF37_4994	COG1418	mRNA catabolic process
BF37_4997	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF37_500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF37_5000	COG2359	stage V sporulation protein S
BF37_5007	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF37_5008	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF37_5009	COG2146	nitrite reductase [NAD(P)H] activity
BF37_501	COG2208	phosphoserine phosphatase activity
BF37_5010	COG1587	Uroporphyrinogen-III synthase
BF37_5010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF37_5012	COG1648	precorrin-2 dehydrogenase activity
BF37_5015	COG2223	nitrite transmembrane transporter activity
BF37_5017	COG0314	molybdopterin synthase activity
BF37_5018	COG0303	'Molybdopterin
BF37_5019	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF37_5020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF37_5021	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF37_5025	COG2181	nitrate reductase activity
BF37_5026	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF37_5027	COG1140	nitrate reductase beta subunit
BF37_5028	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF37_503	COG1191	sigma factor activity
BF37_5031	COG0714	Associated with various cellular activities
BF37_5032	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF37_5033	COG1305	Transglutaminase-like
BF37_5034	COG0386	Belongs to the glutathione peroxidase family
BF37_5039	COG1595	DNA-templated transcription, initiation
BF37_5040	COG0604	alcohol dehydrogenase
BF37_5042	COG0346	lactoylglutathione lyase activity
BF37_5043	COG1082	Xylose isomerase domain protein TIM barrel
BF37_5047	COG2226	methyltransferase
BF37_5052	COG3874	Sporulation protein YtfJ
BF37_5061	COG0456	acetyltransferase
BF37_5067	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_5068	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_5069	COG1819	glycosyl
BF37_5073	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF37_5075	COG0561	phosphatase activity
BF37_5079	COG2211	Major facilitator Superfamily
BF37_508	COG3237	CsbD-like
BF37_5080	COG0154	amidase activity
BF37_5082	COG1876	peptidase activity
BF37_5084	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF37_5088	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF37_5089	COG1114	Component of the transport system for branched-chain amino acids
BF37_5092	COG1253	flavin adenine dinucleotide binding
BF37_5093	COG2839	Protein conserved in bacteria
BF37_5094	COG0702	epimerase
BF37_5097	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF37_5098	COG1607	acyl-coa hydrolase
BF37_5099	COG3689	TIGRFAM TIGR03943 family protein
BF37_51	COG5002	protein histidine kinase activity
BF37_5100	COG0701	Predicted permease
BF37_5102	COG2244	polysaccharide biosynthetic process
BF37_5103	COG0586	Pfam SNARE associated Golgi protein
BF37_5104	COG1051	belongs to the nudix hydrolase family
BF37_5105	COG5337	Spore coat protein CotH
BF37_5107	COG0406	alpha-ribazole phosphatase activity
BF37_5110	COG4166	transmembrane transport
BF37_5112	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF37_5114	COG0702	epimerase
BF37_5116	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF37_5116	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF37_5127	COG0456	acetyltransferase
BF37_5128	COG0523	cobalamin synthesis protein
BF37_5129	COG4989	oxidoreductase activity
BF37_5131	COG1231	oxidoreductase activity
BF37_5133	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF37_5136	COG0783	Belongs to the Dps family
BF37_5137	COG3949	Membrane
BF37_5140	COG0840	transmembrane signaling receptor activity
BF37_5145	COG2814	Major facilitator Superfamily
BF37_5146	COG0667	Aldo Keto reductase
BF37_5147	COG0640	Transcriptional regulator
BF37_5148	COG1404	Belongs to the peptidase S8 family
BF37_5149	COG2002	toxin-antitoxin pair type II binding
BF37_5150	COG0577	efflux transmembrane transporter activity
BF37_5151	COG0577	efflux transmembrane transporter activity
BF37_5158	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF37_5160	COG1279	arginine transmembrane transporter activity
BF37_5161	COG2814	Major facilitator Superfamily
BF37_5162	COG2814	Major facilitator Superfamily
BF37_5164	COG1082	Xylose isomerase domain protein TIM barrel
BF37_5167	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_5168	COG4264	IucA IucC family
BF37_5170	COG1247	-acetyltransferase
BF37_5171	COG1285	pathogenesis
BF37_5173	COG0726	polysaccharide deacetylase
BF37_5174	COG5002	protein histidine kinase activity
BF37_5175	COG0745	RESPONSE REGULATOR receiver
BF37_5177	COG1316	TRANSCRIPTIONal
BF37_518	COG3437	response regulator, receiver
BF37_518	COG2770	Histidine kinase
BF37_5182	COG0460	homoserine dehydrogenase
BF37_5186	COG0726	polysaccharide deacetylase
BF37_5188	COG0300	oxidoreductase activity
BF37_5190	COG5002	protein histidine kinase activity
BF37_5191	COG0745	RESPONSE REGULATOR receiver
BF37_5192	COG1132	(ABC) transporter
BF37_5193	COG1132	(ABC) transporter
BF37_5195	COG1388	LysM domain
BF37_5195	COG0791	NLP P60 protein
BF37_5197	COG1686	Belongs to the peptidase S11 family
BF37_52	COG0582	viral genome integration into host DNA
BF37_5201	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF37_5202	COG4988	ABC transporter
BF37_5203	COG1294	oxidase, subunit
BF37_5204	COG1271	oxidase subunit
BF37_5206	COG1846	Transcriptional regulator
BF37_5208	COG1942	4-Oxalocrotonate Tautomerase
BF37_5210	COG0583	DNA-binding transcription factor activity
BF37_5214	COG0411	ABC transporter
BF37_5216	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_5217	COG2030	dehydratase
BF37_5218	COG0318	PFAM AMP-dependent synthetase and ligase
BF37_5221	COG0523	cobalamin synthesis protein
BF37_5222	COG1231	oxidoreductase activity
BF37_5223	COG0039	L-malate dehydrogenase activity
BF37_5224	COG0628	permease
BF37_5227	COG0778	Nitroreductase
BF37_5228	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF37_5229	COG1959	2 iron, 2 sulfur cluster binding
BF37_523	COG1959	2 iron, 2 sulfur cluster binding
BF37_5230	COG0583	DNA-binding transcription factor activity
BF37_5231	COG0697	spore germination
BF37_5233	COG4549	nuclear export factor GLE1
BF37_5234	COG1276	copper resistance
BF37_5234	COG2372	response to copper ion
BF37_5236	COG1114	Component of the transport system for branched-chain amino acids
BF37_5237	COG1114	Component of the transport system for branched-chain amino acids
BF37_5238	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF37_524	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF37_5244	COG2132	Multicopper oxidase
BF37_5245	COG0006	proline dipeptidase activity
BF37_5249	COG4224	UPF0291 protein
BF37_525	COG2376	Dihydroxyacetone kinase
BF37_5251	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF37_5252	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_5254	COG2390	Transcriptional regulator
BF37_5259	COG0531	amino acid
BF37_5260	COG0531	amino acid
BF37_5262	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF37_5265	COG1914	H( )-stimulated, divalent metal cation uptake system
BF37_527	COG2376	Dihydroxyacetone kinase
BF37_5270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF37_5276	COG4166	transmembrane transport
BF37_5277	COG1073	alpha beta
BF37_5281	COG0427	acetyl-CoA hydrolase
BF37_5282	COG3279	Response regulator of the LytR AlgR family
BF37_5284	COG3384	dioxygenase
BF37_5285	COG2814	Major facilitator Superfamily
BF37_5290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF37_5292	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF37_5293	COG0440	acetolactate synthase activity
BF37_5294	COG0028	Belongs to the TPP enzyme family
BF37_5295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF37_5297	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF37_5301	COG2084	Dehydrogenase
BF37_5304	COG2323	membrane
BF37_5305	COG5566	PFAM Mor transcription activator
BF37_5307	COG0733	neurotransmitter:sodium symporter activity
BF37_5308	COG2244	polysaccharide biosynthetic process
BF37_531	COG1183	phosphatidylcholine synthase activity
BF37_5311	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF37_5312	COG2223	nitrite transmembrane transporter activity
BF37_5313	COG4166	transmembrane transport
BF37_5315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF37_5317	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF37_5318	COG0477	Major facilitator Superfamily
BF37_5319	COG0477	Major facilitator Superfamily
BF37_5321	COG1966	Carbon starvation protein
BF37_5326	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF37_5327	COG1051	belongs to the nudix hydrolase family
BF37_5338	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF37_5339	COG0784	Response regulator, receiver
BF37_5340	COG4191	Histidine kinase
BF37_5341	COG0281	malic enzyme
BF37_5342	COG1027	Aspartate ammonia-lyase
BF37_5344	COG0528	UMP kinase activity
BF37_5345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF37_5348	COG1131	(ABC) transporter
BF37_5355	COG2733	membrane
BF37_536	COG3320	Male sterility
BF37_536	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF37_5362	COG0785	Cytochrome C biogenesis protein
BF37_5366	COG3340	Belongs to the peptidase S51 family
BF37_5367	COG0534	Mate efflux family protein
BF37_5368	COG0534	Mate efflux family protein
BF37_5372	COG0114	fumarate hydratase activity
BF37_5373	COG1757	Na H antiporter
BF37_5374	COG0438	transferase activity, transferring glycosyl groups
BF37_5374	COG1216	Glycosyl transferase, family 2
BF37_5376	COG0701	Predicted permease
BF37_5377	COG0523	cobalamin synthesis protein
BF37_5378	COG0697	spore germination
BF37_5379	COG1802	Transcriptional regulator
BF37_5385	COG0367	asparagine synthase
BF37_5392	COG0406	alpha-ribazole phosphatase activity
BF37_5394	COG1686	Belongs to the peptidase S11 family
BF37_5399	COG1234	tRNA 3'-trailer cleavage
BF37_54	COG1801	Protein of unknown function DUF72
BF37_5400	COG1177	transmembrane transport
BF37_5401	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF37_5402	COG3842	ATPase activity
BF37_5408	COG2329	Antibiotic biosynthesis monooxygenase
BF37_5412	COG1309	transcriptional regulator
BF37_5417	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF37_5418	COG4786	Flagellar basal body rod
BF37_5419	COG1419	protein localization to endoplasmic reticulum
BF37_5420	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF37_5421	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF37_5423	COG1987	bacterial-type flagellum assembly
BF37_5427	COG1776	CheC inhibitor of MCP methylation
BF37_5427	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF37_5429	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF37_5430	COG0741	lytic transglycosylase activity
BF37_5431	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF37_5436	COG0457	Tetratricopeptide repeat
BF37_5436	COG0463	Glycosyl transferase, family 2
BF37_5442	COG0463	Glycosyl transferase, family 2
BF37_5444	COG0835	chemotaxis
BF37_5444	COG0784	Response regulator, receiver
BF37_5454	COG1157	protein secretion by the type III secretion system
BF37_5456	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF37_5458	COG1766	The M ring may be actively involved in energy transduction
BF37_5459	COG1677	Flagellar hook-basal body complex protein FliE
BF37_546	COG0477	Major facilitator Superfamily
BF37_5460	COG1558	bacterial-type flagellum-dependent cell motility
BF37_5461	COG1815	bacterial-type flagellum-dependent cell motility
BF37_5466	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF37_5467	COG1256	bacterial-type flagellum assembly
BF37_5471	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF37_5474	COG1776	CheC inhibitor of MCP methylation
BF37_5474	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF37_5475	COG0643	Histidine kinase
BF37_5475	COG2198	Histidine kinase
BF37_5476	COG2198	Histidine kinase
BF37_5476	COG0643	Histidine kinase
BF37_5477	COG2201	protein-glutamate methylesterase activity
BF37_5478	COG1360	Flagellar Motor Protein
BF37_5479	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF37_5481	COG1923	regulation of RNA biosynthetic process
BF37_5492	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF37_5493	COG2323	membrane
BF37_5495	COG4978	Transcriptional regulator
BF37_5495	COG0789	Transcriptional regulator
BF37_5496	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF37_5497	COG0475	glutathione-regulated potassium exporter activity
BF37_5499	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF37_55	COG3852	Histidine kinase
BF37_5500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF37_5501	COG3162	membrane
BF37_5504	COG1280	lysine exporter protein (LysE YggA)
BF37_5512	COG0328	RNA-DNA hybrid ribonuclease activity
BF37_5516	COG0454	-acetyltransferase
BF37_5519	COG0438	transferase activity, transferring glycosyl groups
BF37_5520	COG1215	transferase activity, transferring glycosyl groups
BF37_5531	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF37_5534	COG0754	glutathionylspermidine amidase activity
BF37_5539	COG0456	acetyltransferase
BF37_554	COG0305	Participates in initiation and elongation during chromosome replication
BF37_5541	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF37_5543	COG2311	Membrane
BF37_5544	COG2233	PERMEase
BF37_5546	COG0024	Methionine aminopeptidase
BF37_5547	COG3173	Aminoglycoside phosphotransferase
BF37_5549	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF37_5550	COG1199	ATP-dependent helicase activity
BF37_5552	COG0116	Belongs to the methyltransferase superfamily
BF37_5554	COG4474	Belongs to the UPF0398 family
BF37_5563	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF37_5563	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF37_5565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF37_5566	COG3935	DnaD domain protein
BF37_557	COG0789	Transcriptional regulator
BF37_557	COG4978	Transcriptional regulator
BF37_5570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF37_5570	COG1199	ATP-dependent helicase activity
BF37_5577	COG0438	transferase activity, transferring glycosyl groups
BF37_5578	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF37_5581	COG1694	Mazg nucleotide pyrophosphohydrolase
BF37_5582	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF37_5584	COG2738	Putative neutral zinc metallopeptidase
BF37_5587	COG4347	Protein of unknown function (DUF1405)
BF37_5589	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF37_5593	COG0457	Tetratricopeptide repeat
BF37_5594	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF37_5597	COG0105	UTP biosynthetic process
BF37_5598	COG0142	geranyltranstransferase activity
BF37_5600	COG0142	geranyltranstransferase activity
BF37_5611	COG2002	toxin-antitoxin pair type II binding
BF37_5613	COG4974	Belongs to the 'phage' integrase family
BF37_562	COG3181	Tripartite tricarboxylate transporter family receptor
BF37_5622	COG2801	Transposase and inactivated derivatives
BF37_5625	COG2801	Transposase and inactivated derivatives
BF37_5627	COG2801	Transposase and inactivated derivatives
BF37_5629	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF37_563	COG4565	transcriptional regulatory protein
BF37_5631	COG4974	Belongs to the 'phage' integrase family
BF37_5636	COG0457	Tetratricopeptide repeat
BF37_5638	COG1923	regulation of RNA biosynthetic process
BF37_564	COG3290	protein histidine kinase activity
BF37_565	COG0477	Major facilitator Superfamily
BF37_5659	COG3344	reverse transcriptase
BF37_5680	COG3344	reverse transcriptase
BF37_571	COG4608	Belongs to the ABC transporter superfamily
BF37_572	COG0444	Belongs to the ABC transporter superfamily
BF37_5725	COG4962	Type ii secretion system protein e
BF37_573	COG0444	Belongs to the ABC transporter superfamily
BF37_574	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF37_575	COG0601	transmembrane transport
BF37_5755	COG2311	Membrane
BF37_5761	COG4196	transglutaminase domain protein
BF37_5762	COG0671	phosphoesterase, PA-phosphatase related
BF37_5766	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF37_5767	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF37_5768	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF37_5772	COG2801	Transposase and inactivated derivatives
BF37_58	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF37_5805	COG1280	lysine exporter protein (LysE YggA)
BF37_5811	COG4166	transmembrane transport
BF37_5813	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF37_582	COG3938	Belongs to the proline racemase family
BF37_5823	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF37_5824	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF37_5838	COG0791	NLP P60 protein
BF37_5838	COG0741	lytic transglycosylase activity
BF37_586	COG1363	Peptidase, m42
BF37_5872	COG1192	Involved in chromosome partitioning
BF37_5877	COG2801	Transposase and inactivated derivatives
BF37_5884	COG1683	Conserved Protein
BF37_5885	COG1309	transcriptional regulator
BF37_589	COG1024	Enoyl-CoA hydratase
BF37_59	COG1392	Phosphate transport regulator
BF37_592	COG1696	Membrane protein involved in D-alanine export
BF37_595	COG4196	transglutaminase domain protein
BF37_596	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF37_598	COG2244	polysaccharide biosynthetic process
BF37_599	COG0653	protein targeting
BF37_60	COG0306	phosphate transporter
BF37_603	COG0659	secondary active sulfate transmembrane transporter activity
BF37_606	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF37_61	COG0730	response to heat
BF37_610	COG0561	phosphatase activity
BF37_613	COG3527	Alpha-acetolactate decarboxylase
BF37_614	COG0028	Belongs to the TPP enzyme family
BF37_620	COG0189	ligase activity
BF37_623	COG1126	abc transporter atp-binding protein
BF37_624	COG0765	amino acid transport
BF37_625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF37_626	COG1132	(ABC) transporter
BF37_627	COG1132	(ABC) transporter
BF37_628	COG1132	(ABC) transporter
BF37_629	COG1012	belongs to the aldehyde dehydrogenase family
BF37_631	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF37_632	COG0531	amino acid
BF37_634	COG0753	catalase activity
BF37_634	COG0693	protein deglycase activity
BF37_635	COG0693	protein deglycase activity
BF37_637	COG2211	Major facilitator Superfamily
BF37_638	COG4533	DNA binding
BF37_639	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF37_64	COG1017	nitric oxide dioxygenase activity
BF37_64	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF37_641	COG1733	regulation of RNA biosynthetic process
BF37_642	COG2814	Major facilitator Superfamily
BF37_643	COG1309	transcriptional regulator
BF37_644	COG2076	Multidrug Resistance protein
BF37_645	COG2076	Multidrug Resistance protein
BF37_647	COG1522	sequence-specific DNA binding
BF37_648	COG0697	spore germination
BF37_651	COG2259	Doxx family
BF37_653	COG1263	PTS System
BF37_653	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_655	COG1737	Transcriptional regulator
BF37_657	COG0475	glutathione-regulated potassium exporter activity
BF37_658	COG0531	amino acid
BF37_665	COG0586	Pfam SNARE associated Golgi protein
BF37_672	COG3546	catalase activity
BF37_673	COG1114	Component of the transport system for branched-chain amino acids
BF37_676	COG5522	Integral membrane protein (intg_mem_TP0381)
BF37_678	COG1136	(ABC) transporter
BF37_679	COG0577	efflux transmembrane transporter activity
BF37_680	COG1388	LysM domain
BF37_680	COG3584	3D domain protein
BF37_684	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF37_685	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF37_686	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF37_686	COG3711	transcriptional antiterminator
BF37_689	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF37_69	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF37_690	COG0604	alcohol dehydrogenase
BF37_691	COG1316	TRANSCRIPTIONal
BF37_693	COG0730	response to heat
BF37_694	COG2210	Belongs to the sulfur carrier protein TusA family
BF37_696	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_698	COG0425	Belongs to the sulfur carrier protein TusA family
BF37_699	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_699	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF37_700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF37_700	COG0425	Belongs to the sulfur carrier protein TusA family
BF37_701	COG1937	Protein conserved in bacteria
BF37_702	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF37_707	COG2719	SpoVR family
BF37_708	COG0778	Nitroreductase
BF37_71	COG1114	Component of the transport system for branched-chain amino acids
BF37_716	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF37_717	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF37_719	COG1609	Transcriptional regulator
BF37_720	COG1263	PTS System
BF37_720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_721	COG1621	beta-fructofuranosidase activity
BF37_722	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF37_726	COG1028	Short-chain dehydrogenase reductase Sdr
BF37_727	COG2252	PERMEase
BF37_73	COG2197	response regulator
BF37_730	COG1846	Transcriptional regulator
BF37_731	COG2814	Major facilitator Superfamily
BF37_732	COG2205	protein histidine kinase activity
BF37_739	COG0351	phosphomethylpyrimidine kinase
BF37_74	COG4585	Histidine kinase
BF37_740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF37_742	COG2104	thiamine diphosphate biosynthetic process
BF37_743	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF37_744	COG0352	thiamine-phosphate diphosphorylase activity
BF37_745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF37_746	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF37_747	COG1116	anion transmembrane transporter activity
BF37_748	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF37_75	COG4758	membrane
BF37_752	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF37_777	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF37_779	COG0581	inorganic phosphate transmembrane transporter activity
BF37_78	COG1757	Na H antiporter
BF37_780	COG0573	inorganic phosphate transmembrane transporter activity
BF37_781	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF37_782	COG1918	ferrous iron import across plasma membrane
BF37_782	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF37_783	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF37_784	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF37_786	COG0531	amino acid
BF37_787	COG0697	spore germination
BF37_788	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF37_791	COG4990	cell redox homeostasis
BF37_792	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF37_793	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF37_796	COG0569	domain protein
BF37_796	COG0475	glutathione-regulated potassium exporter activity
BF37_801	COG2252	PERMEase
BF37_802	COG1113	amino acid transport
BF37_805	COG1114	Component of the transport system for branched-chain amino acids
BF37_806	COG3104	oligopeptide transport
BF37_809	COG1476	TRANSCRIPTIONal
BF37_810	COG1388	LysM domain
BF37_810	COG3584	3D domain protein
BF37_811	COG0840	transmembrane signaling receptor activity
BF37_812	COG1968	undecaprenyl-diphosphatase activity
BF37_817	COG3568	Endonuclease Exonuclease Phosphatase
BF37_82	COG0733	neurotransmitter:sodium symporter activity
BF37_820	COG1063	alcohol dehydrogenase
BF37_824	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF37_825	COG1879	ABC-type sugar transport system periplasmic component
BF37_826	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF37_827	COG1129	ABC transporter
BF37_829	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF37_83	COG1648	precorrin-2 dehydrogenase activity
BF37_830	COG1609	Transcriptional regulator
BF37_831	COG0477	Major facilitator Superfamily
BF37_832	COG0477	Major facilitator Superfamily
BF37_833	COG1846	Transcriptional regulator
BF37_834	COG2271	Major facilitator Superfamily
BF37_836	COG4608	Belongs to the ABC transporter superfamily
BF37_837	COG0601	transmembrane transport
BF37_839	COG0747	negative chemotaxis
BF37_842	COG0659	secondary active sulfate transmembrane transporter activity
BF37_845	COG5002	protein histidine kinase activity
BF37_846	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF37_847	COG2378	regulation of single-species biofilm formation
BF37_852	COG0833	amino acid
BF37_853	COG0765	amino acid transport
BF37_854	COG0765	amino acid transport
BF37_855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF37_856	COG1126	abc transporter atp-binding protein
BF37_857	COG1115	amino acid carrier protein
BF37_858	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF37_860	COG0697	spore germination
BF37_863	COG0366	Alpha amylase catalytic
BF37_864	COG1263	PTS System
BF37_864	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF37_865	COG2188	Transcriptional regulator
BF37_866	COG0531	amino acid
BF37_87	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF37_870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF37_871	COG0714	Associated with various cellular activities
BF37_872	COG4548	von Willebrand factor, type A
BF37_874	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF37_875	COG0156	8-amino-7-oxononanoate synthase activity
BF37_876	COG2226	methyltransferase
BF37_878	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_879	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF37_88	COG0529	Catalyzes the synthesis of activated sulfate
BF37_880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF37_881	COG3104	oligopeptide transport
BF37_884	COG1620	l-lactate permease
BF37_885	COG1027	Aspartate ammonia-lyase
BF37_886	COG1253	flavin adenine dinucleotide binding
BF37_887	COG0346	lactoylglutathione lyase activity
BF37_888	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF37_889	COG1316	TRANSCRIPTIONal
BF37_890	COG2720	vancomycin resistance protein
BF37_894	COG3227	Zinc metalloprotease (Elastase)
BF37_897	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF37_898	COG2217	Heavy metal translocating P-type atpase
BF37_899	COG0640	Transcriptional regulator
BF37_900	COG0531	amino acid
BF37_905	COG3383	formate dehydrogenase (NAD+) activity
BF37_906	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF37_907	COG0454	-acetyltransferase
BF37_907	COG0456	acetyltransferase
BF37_909	COG0745	RESPONSE REGULATOR receiver
BF37_910	COG5002	protein histidine kinase activity
BF37_912	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF37_915	COG0281	malic enzyme
BF37_916	COG3493	citrate carrier protein
BF37_917	COG4565	transcriptional regulatory protein
BF37_918	COG3290	protein histidine kinase activity
BF37_92	COG0019	diaminopimelate decarboxylase activity
BF37_920	COG4990	cell redox homeostasis
BF37_922	COG5002	protein histidine kinase activity
BF37_923	COG0745	RESPONSE REGULATOR receiver
BF37_924	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF37_926	COG0395	ABC-type sugar transport system, permease component
BF37_927	COG1175	transmembrane transport
BF37_928	COG3842	ATPase activity
BF37_929	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF37_933	COG2851	Citrate transporter
BF37_934	COG4565	transcriptional regulatory protein
BF37_935	COG3290	protein histidine kinase activity
BF37_937	COG2268	Band 7 protein
BF37_938	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF37_94	COG1368	sulfuric ester hydrolase activity
BF37_940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF37_944	COG2766	serine protein kinase
BF37_947	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF37_949	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF37_95	COG1183	phosphatidylcholine synthase activity
BF37_951	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF37_952	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF37_977	COG0735	belongs to the Fur family
BF37_978	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF37_98	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF37_982	COG4555	ABC transporter
BF37_984	COG0067	glutamate synthase
BF37_984	COG0069	glutamate synthase activity
BF37_984	COG0070	glutamate synthase
BF37_985	COG4129	membrane
BF37_986	COG1132	(ABC) transporter
BF37_991	COG1194	a g-specific adenine glycosylase
BF37_992	COG1988	membrane-bound metal-dependent
BF37_998	COG1090	epimerase
BF37_999	COG1228	amidohydrolase