locus-tag class description DNQ11_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DNQ11_00015 ENOG410848D S4 domain protein YaaA DNQ11_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DNQ11_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DNQ11_00100 ENOG4105ZMH deoxynucleoside kinase DNQ11_00110 ENOG4105GTG Isochorismatase DNQ11_00120 ENOG4108Z6B deaminase DNQ11_00130 ENOG4105C6E dna polymerase iii DNQ11_00150 ENOG41067KS pro-sigma K processing DNQ11_00185 ENOG4105CXN decarboxylase DNQ11_00195 ENOG4105FA2 dna polymerase iii DNQ11_00200 ENOG4105MA4 psp1 domain protein DNQ11_00210 ENOG41060K3 Methyltransferase DNQ11_00220 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DNQ11_00225 ENOG4105KRN Transcriptional regulator, abrb family DNQ11_00235 ENOG4105F8V Hydrolase, tatD family DNQ11_00240 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) DNQ11_00250 ENOG4105XFA sporulation peptidase YabG DNQ11_00255 ENOG4105W42 Veg protein DNQ11_00270 ENOG4105DFT pur operon repressor DNQ11_00280 ENOG4105KME endoribonuclease L-psp DNQ11_00295 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DNQ11_00300 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) DNQ11_00310 ENOG4108JA2 transcriptioN-repair coupling factor DNQ11_00315 ENOG4108M14 stage v sporulation protein t DNQ11_00325 ENOG4108IY2 MazG family DNQ11_00330 ENOG41082I2 s4 domain protein DNQ11_00335 ENOG4105VYY sporulation protein yabp DNQ11_00350 ENOG41060GV RNA binding s1 domain protein DNQ11_00370 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DNQ11_00375 ENOG4108UGV hypoxanthine phosphoribosyltransferase DNQ11_00380 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DNQ11_00395 ENOG4105C6T cysteine synthase DNQ11_00400 ENOG4105CRQ synthase (Component I) DNQ11_00405 ENOG4105DDQ anthranilate synthase DNQ11_00410 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 DNQ11_00415 ENOG4105EEI dihydropteroate synthase DNQ11_00420 ENOG4105KRF dihydroneopterin aldolase DNQ11_00425 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DNQ11_00435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DNQ11_00465 ENOG4108Z0C Uvrb UvrC protein DNQ11_00480 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DNQ11_00490 ENOG4105CTP PilT protein domain protein DNQ11_00510 ENOG4105D7W serine acetyltransferase DNQ11_00525 ENOG4105C2N RNA methyltransferase TrmH family group 3 DNQ11_00530 ENOG4105M0M Tetracycline resistance protein DNQ11_00535 ENOG4105QIV RNA polymerase DNQ11_00550 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DNQ11_00575 ENOG4107Y49 methyltransferase DNQ11_00585 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DNQ11_00590 ENOG4105XPM ribosomal protein DNQ11_00695 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DNQ11_00720 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DNQ11_00730 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DNQ11_00740 ENOG41067V7 50S ribosomal protein L36 DNQ11_00770 ENOG4108JJB ABC transporter DNQ11_00775 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DNQ11_00780 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DNQ11_00805 ENOG4105D1F ATP-binding protein DNQ11_00820 ENOG4108NMV polysaccharide deacetylase DNQ11_00905 ENOG4105C8B TIGR00159 family DNQ11_00910 ENOG4107U5W ybbr family DNQ11_00925 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DNQ11_00930 ENOG4108VQT Alpha beta hydrolase fold protein DNQ11_00950 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) DNQ11_00960 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein DNQ11_00995 ENOG4108UMI ABC transporter, permease DNQ11_01000 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_01005 ENOG4105D01 (LipO)protein DNQ11_01010 ENOG4105EE1 crotonyl-CoA reductase DNQ11_01020 ENOG4105IQ5 FAD linked oxidase domain protein DNQ11_01035 ENOG4105C2C drug resistance transporter, Bcr CflA DNQ11_01050 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DNQ11_01055 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DNQ11_01060 ENOG4105C3U ABC transporter DNQ11_01065 ENOG4108JQ7 (ABC) transporter DNQ11_01095 ENOG4108J59 Extracellular solute-binding protein, family 5 DNQ11_01100 ENOG4108J59 Extracellular solute-binding protein, family 5 DNQ11_01110 ENOG4105II7 pyrroline-5-carboxylate reductase DNQ11_01120 ENOG4107XDY Nicotinamide Mononucleotide Transporter DNQ11_01130 ENOG4105E0C molybdate abc transporter DNQ11_01140 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family DNQ11_01155 ENOG4105EGI Transcriptional regulator DNQ11_01175 ENOG4105F6E Acyl-transferase DNQ11_01200 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DNQ11_01215 ENOG4108RE7 deoxyribonuclease DNQ11_01220 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) DNQ11_01245 ENOG4105C5H ABC transporter DNQ11_01260 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein DNQ11_01270 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DNQ11_01275 ENOG4105C3U ABC transporter DNQ11_01280 ENOG4108JQ7 (ABC) transporter DNQ11_01320 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DNQ11_01325 ENOG4105ERH Fumarylacetoacetate hydrolase DNQ11_01340 ENOG4108SC4 )-transporter DNQ11_01350 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DNQ11_01365 ENOG4107ZXI Rhomboid family DNQ11_01375 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein DNQ11_01380 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DNQ11_01390 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) DNQ11_01490 ENOG4105K8N protein family UPF0079, ATPase DNQ11_01495 ENOG41072GX Peptidase M22 Glycoprotease DNQ11_01500 ENOG410801F ribosomal-protein-alanine acetyltransferase DNQ11_01505 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DNQ11_01510 ENOG4105C5H ABC transporter DNQ11_01525 ENOG4108TYN CAAX amino terminal protease family protein DNQ11_01545 ENOG4105C7N Xanthine uracil vitamin C permease DNQ11_01555 ENOG4105BZU Histidine kinase DNQ11_01590 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DNQ11_01635 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DNQ11_01655 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_01680 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DNQ11_01685 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DNQ11_01690 ENOG4105C83 adenylosuccinate lyase DNQ11_01700 ENOG4105VR9 phosphoribosylformylglycinamidine synthase DNQ11_01725 ENOG4108V3E phosphoribosylglycinamide formyltransferase DNQ11_01735 ENOG4105C12 Phosphoribosylglycinamide synthetase DNQ11_01765 ENOG4105C4R Atp-dependent dna helicase DNQ11_01795 ENOG4108W2Y isochorismatase DNQ11_01805 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_01810 ENOG4108UMI ABC transporter, permease DNQ11_01815 ENOG4105D01 (LipO)protein DNQ11_01835 ENOG410834F Transcriptional regulator DNQ11_01860 ENOG4105CBD Diacylglycerol kinase DNQ11_01865 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DNQ11_01870 ENOG4108JPW Aminotransferase DNQ11_01880 ENOG4105C26 Dehydrogenase DNQ11_01885 ENOG4105KPY Small multidrug resistance protein DNQ11_01905 ENOG4105D9N nucleoside DNQ11_01910 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DNQ11_01925 ENOG4108W15 Protein of unknown function (DUF1456) DNQ11_01940 ENOG4105DTQ mandelate racemase muconate lactonizing DNQ11_01950 ENOG4105DFD Na H antiporter DNQ11_01970 ENOG4105D3R alkyl hydroperoxide reductase DNQ11_01975 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) DNQ11_01985 ENOG4107W7X Aldolase DNQ11_01990 ENOG4105EHG Permease protein DNQ11_01995 ENOG4105DQ5 transport system permease protein DNQ11_02000 ENOG4108V5C ABC transporter DNQ11_02030 ENOG4106UIA DNQ11_02035 ENOG4106UIA DNQ11_02070 ENOG4105BZU Histidine kinase DNQ11_02090 ENOG410756H nucleotidyltransferase DNQ11_02095 ENOG4105D2S major facilitator superfamily DNQ11_02110 ENOG4105E5Q amino acid AbC transporter DNQ11_02115 ENOG4105EAB amino acid AbC transporter DNQ11_02130 ENOG4105C8Q Methyl-accepting chemotaxis DNQ11_02135 ENOG4105C8Q Methyl-accepting chemotaxis DNQ11_02145 ENOG4105CI1 PTS System DNQ11_02175 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter DNQ11_02190 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DNQ11_02205 ENOG4105C5H ABC transporter DNQ11_02230 ENOG41062JF Transcriptional regulator DNQ11_02250 ENOG4105DEU major facilitator superfamily DNQ11_02265 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) DNQ11_02280 ENOG4108N0M stress protein DNQ11_02285 ENOG4106FN3 tellurium resistance protein DNQ11_02290 ENOG4106FN3 tellurium resistance protein DNQ11_02295 ENOG4107TS3 membrane protein, TerC DNQ11_02300 ENOG4108TTB tellurium resistance protein DNQ11_02320 ENOG4105KJF protein tyrosine phosphatase DNQ11_02330 ENOG4107U9T Pfam:Ribonuclease_BN DNQ11_02340 ENOG4105C59 p-type ATPase DNQ11_02345 ENOG4108IPJ Membrane DNQ11_02365 ENOG4107ZTW SNARE associated Golgi DNQ11_02380 ENOG410606W general stress protein DNQ11_02385 ENOG4105UPD Calcium Proton DNQ11_02425 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DNQ11_02430 ENOG4105VTR Integrase DNQ11_02435 ENOG4108IMY Transcriptional regulator DNQ11_02745 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DNQ11_02755 ENOG4108JUB Transcriptional regulator DNQ11_02765 ENOG4108IQI permease DNQ11_02800 ENOG4105CSV Glutaminase DNQ11_02815 ENOG4108A04 Beta-lactamase DNQ11_02830 ENOG4105CKK Glycosyl transferase, family 2 DNQ11_02840 ENOG4107QQG Dehydrogenase DNQ11_02845 ENOG4105C3I Nad-dependent epimerase dehydratase DNQ11_02865 ENOG4105F1A Pyruvate formate-lyase DNQ11_02885 ENOG4105CI2 imidazolone-5-propionate hydrolase DNQ11_02890 ENOG4105ECP epimerase DNQ11_02920 ENOG41067AE Membrane-bound metal-dependent hydrolase DNQ11_02925 ENOG4105CEN a g-specific adenine glycosylase DNQ11_02930 ENOG4106BXE DNQ11_02950 ENOG4105BZ1 (ABC) transporter DNQ11_02955 ENOG4107NBY Membrane DNQ11_02960 ENOG4105CBC glutamate synthase DNQ11_02970 ENOG4108IUW ABC transporter DNQ11_02990 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DNQ11_02995 ENOG4105G5W regulator Fur family DNQ11_03115 ENOG4108JQC penicillin-binding protein 1A DNQ11_03120 ENOG4107ZQN disulfide bond DNQ11_03130 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DNQ11_03140 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DNQ11_03145 ENOG4105BZU Histidine kinase DNQ11_03155 ENOG4105CYN Serine protein kinase DNQ11_03185 ENOG4105C94 Transporter DNQ11_03200 ENOG4105DZ6 Band 7 protein DNQ11_03210 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism DNQ11_03215 ENOG4108MRH transcriptional regulatory protein DNQ11_03220 ENOG4105D4T Citrate transporter DNQ11_03245 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DNQ11_03250 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_03255 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DNQ11_03260 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component DNQ11_03265 ENOG4105BZ7 extracellular solute-binding protein family 1 DNQ11_03270 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) DNQ11_03275 ENOG4108STX response regulator DNQ11_03280 ENOG4105US7 Histidine kinase DNQ11_03305 ENOG4108MRH transcriptional regulatory protein DNQ11_03315 ENOG4105C6K Malic enzyme DNQ11_03325 ENOG4108UZ3 Transporter DNQ11_03330 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DNQ11_03340 ENOG4105BZU Histidine kinase DNQ11_03345 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_03355 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DNQ11_03360 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DNQ11_03365 ENOG4108JB9 formate dehydrogenase DNQ11_03385 ENOG4105CUB amino acid DNQ11_03400 ENOG4105C59 p-type ATPase DNQ11_03405 ENOG4105DAP Nicotinate phosphoribosyltransferase DNQ11_03440 ENOG41073R8 VanW family DNQ11_03445 ENOG4108KGH TRANSCRIPTIONal DNQ11_03450 ENOG4105D9N nucleoside DNQ11_03455 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase DNQ11_03460 ENOG4105C37 (CBS) domain DNQ11_03465 ENOG4108IJ0 Aspartate ammonia-lyase DNQ11_03470 ENOG4105DAA L-lactate DNQ11_03485 ENOG4105DUX Transporter DNQ11_03490 ENOG4108MES Periplasmic binding protein DNQ11_03495 ENOG4105DQ5 transport system permease protein DNQ11_03500 ENOG4108IHU transport system permease protein DNQ11_03505 ENOG4105E0A ABC, transporter DNQ11_03510 ENOG4105DMQ Methyltransferase DNQ11_03520 ENOG4105EXW epimerase dehydratase DNQ11_03530 ENOG4107T89 von Willebrand factor, type A DNQ11_03535 ENOG4105GMT ATPase associated with various cellular activities aaa_5 DNQ11_03540 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DNQ11_03555 ENOG4105BZU Histidine kinase DNQ11_03560 ENOG4105D5Q Arginine ornithine antiporter DNQ11_03565 ENOG4107414 GntR family transcriptional regulator DNQ11_03570 ENOG4105C5Y PTS System DNQ11_03575 ENOG4105CG3 alpha amylase, catalytic region DNQ11_03590 ENOG4105E1K spore germination protein DNQ11_03600 ENOG4105CRN Aminoglycoside phosphotransferase DNQ11_03605 ENOG4105BZG amino acid carrier protein DNQ11_03610 ENOG4105CDA abc transporter atp-binding protein DNQ11_03615 ENOG4105CT1 (ABC) transporter DNQ11_03620 ENOG4105EAD ABC transporter DNQ11_03625 ENOG4105DRP amino acid AbC transporter DNQ11_03630 ENOG4108IQI permease DNQ11_03655 ENOG4105D29 Helix-turn-helix type 11 domain protein DNQ11_03660 ENOG4105NAE bifunctional deaminase-reductase domain protein DNQ11_03665 ENOG4105BZU Histidine kinase DNQ11_03680 ENOG4105CHH sulfate transporter DNQ11_03685 ENOG41068KF Universal stress protein DNQ11_03695 ENOG4105DEF Extracellular solute-binding protein, family 5 DNQ11_03705 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DNQ11_03710 ENOG4108JQ7 (ABC) transporter DNQ11_03720 ENOG4105CXY transporter DNQ11_03725 ENOG41067TZ transcriptional regulator, MarR family DNQ11_03735 ENOG4105ETE Transcriptional regulator (LacI family DNQ11_03740 ENOG4108RVA ribokinase DNQ11_03750 ENOG4105C2J ABC transporter DNQ11_03755 ENOG4105CNN ABC, transporter DNQ11_03760 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DNQ11_03765 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DNQ11_03825 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DNQ11_03830 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer DNQ11_03835 ENOG41069ER domain protein DNQ11_03840 ENOG4105VZ8 Transcriptional regulator DNQ11_03845 ENOG4107D63 DNQ11_03855 ENOG4105DUX Transporter DNQ11_03875 ENOG4105C85 amino acid DNQ11_03880 ENOG4105C7N Xanthine uracil vitamin C permease DNQ11_03920 ENOG4105BZ9 Cytochrome C oxidase, subunit I DNQ11_03925 ENOG4105E2S oxidase) subunit II DNQ11_03930 ENOG4108IQI permease DNQ11_03945 ENOG4106CAD Protein of unknown function (DUF3311) DNQ11_03950 ENOG4105E1V na solute symporter DNQ11_03965 ENOG4108NHD germination protein DNQ11_03975 ENOG4105CE1 Ferrous iron transport protein b DNQ11_03980 ENOG4105CE1 Ferrous iron transport protein b DNQ11_03985 ENOG4105CE1 Ferrous iron transport protein b DNQ11_03990 ENOG4105CVA phosphate DNQ11_03995 ENOG4105C8U phosphate abc transporter DNQ11_04000 ENOG4105E2Z phosphate ABC transporter (Permease DNQ11_04130 ENOG41080XQ Signal transduction protein with cbs domains DNQ11_04155 ENOG4105ETU transcriptional activator (TenA DNQ11_04165 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DNQ11_04175 ENOG4108VEU Thiamine monophosphate synthase DNQ11_04180 ENOG41080HI glycine oxidase DNQ11_04195 ENOG4105D06 uba thif-type nad fad binding protein DNQ11_04200 ENOG4105DWF phosphomethylpyrimidine kinase DNQ11_04255 ENOG4108INS Transcriptional regulator DNQ11_04270 ENOG4105C7N Xanthine uracil vitamin C permease DNQ11_04300 ENOG4105C5Y PTS System DNQ11_04360 ENOG4107Y03 Nitroreductase DNQ11_04365 ENOG4105ED1 spovr family DNQ11_04395 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase DNQ11_04400 ENOG4105XTG Pfam:DUF156 DNQ11_04405 ENOG4105VFE sira family DNQ11_04410 ENOG4107TPS domain protein DNQ11_04415 ENOG4105VFE sira family DNQ11_04420 ENOG41085GJ domain protein DNQ11_04430 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DNQ11_04435 ENOG41087NI Sulfite exporter TauE/SafE DNQ11_04445 ENOG4108KGH TRANSCRIPTIONal DNQ11_04470 ENOG4105EMD TRANSCRIPTIONal DNQ11_04475 ENOG4105VCP PTS System DNQ11_04480 ENOG4105VZJ PTS System DNQ11_04500 ENOG41069ER domain protein DNQ11_04505 ENOG4107RBB ABC transporter, permease DNQ11_04510 ENOG4105C19 ABC transporter DNQ11_04540 ENOG4105WEF catalase DNQ11_04575 ENOG4107T5V SNARE associated Golgi DNQ11_04615 ENOG4105CUB amino acid DNQ11_04620 ENOG4107RWR Sodium hydrogen exchanger DNQ11_04630 ENOG4106KNT transcriptional regulator DNQ11_04665 ENOG4108PCN EamA-like transporter family DNQ11_04670 ENOG4108YXU transcriptional regulator AsnC family DNQ11_04680 ENOG4105KPY Small multidrug resistance protein DNQ11_04685 ENOG4105KPY Small multidrug resistance protein DNQ11_04710 ENOG4105NF4 modulator of drug activity DNQ11_04715 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DNQ11_04720 ENOG4105E5W Transporter DNQ11_04730 ENOG4107RKG DJ-1/PfpI family DNQ11_04735 ENOG4105CH6 catalase DNQ11_04745 ENOG4105D5Q Arginine ornithine antiporter DNQ11_04750 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DNQ11_04760 ENOG4105C26 Dehydrogenase DNQ11_04780 ENOG4105BZ1 (ABC) transporter DNQ11_04800 ENOG4105DRP amino acid AbC transporter DNQ11_04805 ENOG4105CDA abc transporter atp-binding protein DNQ11_04820 ENOG410839P DNQ11_04855 ENOG4107FQX Alpha-acetolactate decarboxylase DNQ11_04880 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DNQ11_04890 ENOG4105D4P Coproporphyrinogen iii oxidase DNQ11_04905 ENOG4105CHH sulfate transporter DNQ11_04945 ENOG4106AKK s-layer domain-containing protein DNQ11_04955 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DNQ11_04960 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DNQ11_04980 ENOG4105CGU Enoyl-CoA hydratase DNQ11_05000 ENOG4105DER m42 family DNQ11_05020 ENOG4105CTU Proline racemase DNQ11_05060 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DNQ11_05070 ENOG4108JQ7 (ABC) transporter DNQ11_05080 ENOG4105PKS Excinuclease abc c subunit domain protein DNQ11_05115 ENOG4105CSH Transporter DNQ11_05125 ENOG4108MRH transcriptional regulatory protein DNQ11_05175 ENOG4105CDU Replicative dna helicase DNQ11_05225 ENOG4105C0R drug resistance transporter emrb qaca subfamily DNQ11_05280 ENOG4108IG5 Transcriptional regulator DNQ11_05300 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DNQ11_05325 ENOG4105CMT Dihydroxyacetone kinase DNQ11_05340 ENOG4105CMT Dihydroxyacetone kinase DNQ11_05345 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DNQ11_05350 ENOG410847I Transcriptional regulator, BadM Rrf2 family DNQ11_05385 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DNQ11_05465 ENOG4105WN5 stage II sporulation protein DNQ11_05475 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_05485 ENOG4108MJI response regulator DNQ11_05490 ENOG4105BZU Histidine kinase DNQ11_05495 ENOG4105BZU Histidine kinase DNQ11_05520 ENOG4105K8R UPF0145 protein DNQ11_05555 ENOG4107VRP DNA repair exonuclease DNQ11_05560 ENOG4106D4I domain protein DNQ11_05580 ENOG4108IND Tetr family transcriptional regulator DNQ11_05585 ENOG4105EQ0 Major Facilitator superfamily DNQ11_05600 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase DNQ11_05615 ENOG4108MUZ hydrolase DNQ11_05635 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DNQ11_05650 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DNQ11_05670 ENOG4105EMN RNA polymerase sigma factor DNQ11_05695 ENOG4105C57 major facilitator superfamily DNQ11_05700 ENOG4105C0R drug resistance transporter emrb qaca subfamily DNQ11_05710 ENOG4105EEM helicase DNQ11_05715 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DNQ11_05745 ENOG4105K59 histidine triad (HIT) protein DNQ11_05785 ENOG410905X membrane-flanked domain protein DNQ11_05835 ENOG410905X membrane-flanked domain protein DNQ11_05840 ENOG4105CKV Membrane DNQ11_05845 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation DNQ11_05850 ENOG4105BZ4 penicillin-binding protein DNQ11_05855 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DNQ11_05865 ENOG4105C1Q protoporphyrinogen oxidase DNQ11_05890 ENOG4105NA0 Transcriptional regulator DNQ11_05935 ENOG4106AXD DNQ11_05940 ENOG4108RQ5 Beta-lactamase domain-containing protein DNQ11_05945 ENOG4105DF9 Lipoate-protein, ligase DNQ11_05955 ENOG4105CEY Amp-dependent synthetase and ligase DNQ11_05985 ENOG4105CNA YD repeat protein DNQ11_06020 ENOG4105ENX hydrolase DNQ11_06030 ENOG4107TVP HD domain protein DNQ11_06040 ENOG4108AEY RNA polymerase sigma factor DNQ11_06045 ENOG41086D8 Transcriptional regulator DNQ11_06065 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_06090 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 DNQ11_06095 ENOG4105C8Q Methyl-accepting chemotaxis DNQ11_06115 ENOG4105ZU5 s-layer protein DNQ11_06120 ENOG4107QP3 malate synthase g DNQ11_06135 ENOG4105VEQ Cold shock protein DNQ11_06150 ENOG4105XVF Competence transcription factor DNQ11_06165 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination DNQ11_06170 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation DNQ11_06215 ENOG4105ERH Fumarylacetoacetate hydrolase DNQ11_06240 ENOG4105CAQ asparagine synthetase DNQ11_06245 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) DNQ11_06250 ENOG4105CH6 catalase DNQ11_06255 ENOG4105BZU Histidine kinase DNQ11_06280 ENOG4105QNR S1 RNA binding domain protein DNQ11_06290 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DNQ11_06300 ENOG4107AYK membrAne DNQ11_06305 ENOG41073B9 DNQ11_06315 ENOG4108KP7 hydrolase DNQ11_06330 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DNQ11_06360 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DNQ11_06365 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DNQ11_06385 ENOG4105C31 Tryptophanyl-tRNA synthetase DNQ11_06405 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DNQ11_06410 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DNQ11_06420 ENOG4108JQ7 (ABC) transporter DNQ11_06425 ENOG4105UQX Mate efflux family protein DNQ11_06450 ENOG4108ZCF integral membrane protein DNQ11_06460 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DNQ11_06470 ENOG4105DPN Oligoendopeptidase f DNQ11_06485 ENOG4108Z18 K06886 hemoglobin DNQ11_06490 ENOG4105MIX Adenylate cyclase DNQ11_06505 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DNQ11_06510 ENOG4105EMS pseudouridine synthase DNQ11_06530 ENOG4105K64 Glycosyl transferase, family 2 DNQ11_06550 ENOG4107TVC Glycosyl transferase, family 2 DNQ11_06570 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DNQ11_06575 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DNQ11_06585 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DNQ11_06635 ENOG4108WVJ 2'-5' rna ligase DNQ11_06660 ENOG4105CK7 Sodium proline symporter DNQ11_06670 ENOG4105CRQ synthase (Component I) DNQ11_06675 ENOG4105DDQ anthranilate synthase DNQ11_06775 ENOG4105C7S Dehydrogenase DNQ11_06785 ENOG4105VZ8 Transcriptional regulator DNQ11_06845 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) DNQ11_06860 ENOG4105DZ1 carboxypeptidase DNQ11_06865 ENOG4105VFR signal peptidase DNQ11_06900 ENOG4105C26 Dehydrogenase DNQ11_06905 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_06910 ENOG4105F38 ABC transporter, permease DNQ11_06915 ENOG4105D38 putrescine abc transporter DNQ11_06920 ENOG4107RUE extracellular solute-binding protein family 1 DNQ11_06930 ENOG4105EYF MMPL domain protein DNQ11_06940 ENOG4108YBP pseudouridine synthase DNQ11_06950 ENOG4105K4I Scp-like extracellular DNQ11_06955 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DNQ11_06960 ENOG4105CQB FAD linked oxidase domain protein DNQ11_06975 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_06980 ENOG4105BZU Histidine kinase DNQ11_06985 ENOG4105JXH GntR family transcriptional regulator DNQ11_07005 ENOG4106A3R peptidase DNQ11_07015 ENOG4108QTI )-transporter DNQ11_07020 ENOG4107TS3 membrane protein, TerC DNQ11_07025 ENOG4105CZN Potassium uptake protein DNQ11_07030 ENOG410681C small acid-soluble spore protein DNQ11_07035 ENOG4108Z7G MaoC domain protein dehydratase DNQ11_07055 ENOG4105CHR reductase DNQ11_07065 ENOG4105MWK D-amino acid dehydrogenase, small subunit DNQ11_07090 ENOG4105C4Y ABC transporter DNQ11_07105 ENOG4108KAZ Involved in phosphonate degradation (By similarity) DNQ11_07120 ENOG4105E98 transcriptional regulator DeoR family DNQ11_07145 ENOG4105PXI polysaccharide deacetylase DNQ11_07155 ENOG4105BZU Histidine kinase DNQ11_07160 ENOG41090MY MarR family Transcriptional regulator DNQ11_07170 ENOG4106DF1 DNQ11_07180 ENOG4105BZU Histidine kinase DNQ11_07190 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DNQ11_07195 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DNQ11_07240 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) DNQ11_07260 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DNQ11_07265 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DNQ11_07270 ENOG4105CZV ABC transporter DNQ11_07280 ENOG4105CJ1 ABC, transporter DNQ11_07320 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DNQ11_07325 ENOG4105EA8 2-Nitropropane dioxygenase DNQ11_07330 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DNQ11_07340 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DNQ11_07365 ENOG4105NQC Flavodoxin DNQ11_07405 ENOG4107QMU Mate efflux family protein DNQ11_07410 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DNQ11_07440 ENOG4105CZN Potassium uptake protein DNQ11_07445 ENOG41063Y9 DNQ11_07450 ENOG4105KBJ sporulation protein ytfj DNQ11_07480 ENOG4105CM2 brancheD-chain amino acid aminotransferase DNQ11_07485 ENOG4105C7K acetolactate synthase DNQ11_07490 ENOG4108ZP8 Acetolactate synthase small subunit DNQ11_07495 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DNQ11_07505 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DNQ11_07530 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DNQ11_07565 ENOG4107RVV histidinol phosphate phosphatase, hisj family DNQ11_07580 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DNQ11_07585 ENOG4105E0M Sulfatase DNQ11_07595 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DNQ11_07615 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) DNQ11_07620 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DNQ11_07630 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DNQ11_07635 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DNQ11_07640 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein DNQ11_07650 ENOG4105C8J )-transporter DNQ11_07670 ENOG4105DFD Na H antiporter DNQ11_07690 ENOG4105ENE Histidine kinase DNQ11_07695 ENOG4105WH1 Two component transcriptional regulator luxr family DNQ11_07715 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DNQ11_07740 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DNQ11_07765 ENOG4105CJ3 phosphate transporter DNQ11_07770 ENOG4107GRR phosphate transport regulator DNQ11_07775 ENOG4105BZ4 penicillin-binding protein DNQ11_07795 ENOG4105BZU Histidine kinase DNQ11_07800 ENOG4105I3N Conserved Protein DNQ11_07815 ENOG4105BZU Histidine kinase DNQ11_07860 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DNQ11_07865 ENOG4105DZ1 carboxypeptidase DNQ11_07870 ENOG4108JIC nucleoside recognition domain protein DNQ11_07880 ENOG4105FE9 pseudouridine synthase DNQ11_07890 ENOG4107TWT Cytochrome c biogenesis protein DNQ11_07895 ENOG4105CRE cytochrome C DNQ11_07900 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_07905 ENOG4105BZU Histidine kinase DNQ11_07910 ENOG4108WBT adenosyltransferase DNQ11_07925 ENOG4108SAX Membrane DNQ11_07935 ENOG4105T7X DNQ11_07940 ENOG4105C9U ATP-dependent DNA helicase RecQ DNQ11_07945 ENOG4105I7S Abortive infection protein DNQ11_07960 ENOG4107X2D transcriptional regulator, merr family DNQ11_07965 ENOG4108S6Z Negative regulator of genetic competence DNQ11_07990 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase DNQ11_07995 ENOG4105HDK L-asparaginase DNQ11_08030 ENOG4105S2F DNQ11_08035 ENOG41065D1 DNQ11_08065 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) DNQ11_08080 ENOG4105XXQ heptaprenyl diphosphate synthase component I DNQ11_08090 ENOG4105EAH synthase DNQ11_08110 ENOG4105CIH Imidazole acetol-phosphate transaminase DNQ11_08115 ENOG41068YB TPR repeat-containing protein DNQ11_08130 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) DNQ11_08135 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DNQ11_08140 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit DNQ11_08175 ENOG4108JYZ YitT family DNQ11_08185 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase DNQ11_08200 ENOG4105FJR Lmbe family DNQ11_08205 ENOG4105CPK Glycosyl transferase (Group 1 DNQ11_08245 ENOG4105DVT helicase DNQ11_08250 ENOG4105YAC DNQ11_08270 ENOG4105CSM endonuclease III DNQ11_08280 ENOG4105BZ4 penicillin-binding protein DNQ11_08340 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DNQ11_08350 ENOG4105DVT helicase DNQ11_08355 ENOG4105CTD carboxy-peptidase DNQ11_08370 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DNQ11_08380 ENOG4105C2W permease DNQ11_08385 ENOG4105DHF Membrane DNQ11_08395 ENOG410890F Dynamin family DNQ11_08405 ENOG4108W0I acetyltransferase DNQ11_08415 ENOG4105KHC sulfurtransferase DNQ11_08440 ENOG4106032 Glutathionylspermidine synthase DNQ11_08505 ENOG4105CPK Glycosyl transferase (Group 1 DNQ11_08520 ENOG4108SZE gCN5-related N-acetyltransferase DNQ11_08540 ENOG41081VK Ribonuclease DNQ11_08605 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DNQ11_08620 ENOG4107RWR Sodium hydrogen exchanger DNQ11_08625 ENOG4105CN5 Metallo-Beta-Lactamase DNQ11_08630 ENOG4108Z5V transcriptional regulator, merr family DNQ11_08640 ENOG4105H67 Protein of unknown function (DUF421) DNQ11_08645 ENOG41080C8 DUF218 domain DNQ11_08700 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DNQ11_08710 ENOG4107R0U MotA TolQ exbB proton channel DNQ11_08715 ENOG4105ER2 Ompa motb domain protein DNQ11_08720 ENOG4107YTP response regulator receiver protein DNQ11_08730 ENOG4105DD5 Flagellar motor switch protein DNQ11_08745 ENOG4105BZU Histidine kinase DNQ11_08765 ENOG4105E1Q flagellar hook-associated protein DNQ11_08790 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) DNQ11_08795 ENOG4108ZC9 flagellar basal-body rod protein flgc DNQ11_08800 ENOG41075Z6 flagellar hook-basal body complex protein fliE DNQ11_08810 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DNQ11_08845 ENOG4105BZE flagellar hook protein, FlgE DNQ11_08860 ENOG4107R88 Chemotaxis protein (CheV) DNQ11_08870 ENOG4105K64 Glycosyl transferase, family 2 DNQ11_08910 ENOG4107TVC Glycosyl transferase, family 2 DNQ11_08925 ENOG4105I03 Flagellin DNQ11_08930 ENOG4105E4C Lytic transglycosylase catalytic DNQ11_08945 ENOG4105DD5 Flagellar motor switch protein DNQ11_08955 ENOG4105CN7 Flagellar biosynthetic protein FliP DNQ11_08960 ENOG4105VS8 Flagellar biosynthetic protein fliq DNQ11_08970 ENOG4105D00 flagellar biosynthetic protein flhB DNQ11_08975 ENOG4105D7B Flagellar biosynthesis protein flha DNQ11_08980 ENOG4105FZW flagellar biosynthesis regulator FlhF DNQ11_08985 ENOG4105KTQ flagellar basal-body rod protein DNQ11_08990 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DNQ11_09015 ENOG4108RZE Tetr family transcriptional regulator DNQ11_09035 ENOG4105KAC Antibiotic biosynthesis monooxygenase DNQ11_09060 ENOG4105DUM transcriptional regulator, lysR family DNQ11_09065 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_09070 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DNQ11_09075 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component DNQ11_09080 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DNQ11_09120 ENOG4105CVJ phosphoglycerate mutase DNQ11_09150 ENOG4105CAQ asparagine synthetase DNQ11_09170 ENOG4105PGM cation diffusion facilitator family transporter DNQ11_09180 ENOG4105DRR Transcriptional regulator, GntR family DNQ11_09185 ENOG4108UZ3 Transporter DNQ11_09190 ENOG4105CKI cobalamin synthesis protein DNQ11_09200 ENOG4108PJD permease DNQ11_09215 ENOG4105DFD Na H antiporter DNQ11_09220 ENOG4105C9Q fumarate hydratase class II DNQ11_09250 ENOG4105EC3 peptidase S51, dipeptidase E DNQ11_09270 ENOG4107QIV Cytochrome c biogenesis protein DNQ11_09305 ENOG4106BRA Membrane DNQ11_09345 ENOG4105CJ1 ABC, transporter DNQ11_09365 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) DNQ11_09375 ENOG4108IJ0 Aspartate ammonia-lyase DNQ11_09380 ENOG4105C6K Malic enzyme DNQ11_09455 ENOG4105FVX DNQ11_09495 ENOG4105CSR polyphosphate kinase 2 DNQ11_09520 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DNQ11_09530 ENOG4105EU0 Major facilitator Superfamily DNQ11_09535 ENOG4105C6T cysteine synthase DNQ11_09555 ENOG4105C8J )-transporter DNQ11_09565 ENOG4105X5K response regulator receiver protein DNQ11_09570 ENOG4105H67 Protein of unknown function (DUF421) DNQ11_09590 ENOG4106KE4 Dehydrogenase DNQ11_09610 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DNQ11_09615 ENOG4105CHR reductase DNQ11_09620 ENOG4105CM2 brancheD-chain amino acid aminotransferase DNQ11_09625 ENOG4105C7K acetolactate synthase DNQ11_09630 ENOG4108ZP8 Acetolactate synthase small subunit DNQ11_09635 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DNQ11_09645 ENOG4105C7B Threonine dehydratase DNQ11_09670 ENOG4105C6X Major Facilitator DNQ11_09675 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DNQ11_09685 ENOG4105DY9 regulatoR DNQ11_09690 ENOG4105CYC Transferase DNQ11_09710 ENOG4105F6J Alpha beta hydrolase fold DNQ11_09720 ENOG4108J59 Extracellular solute-binding protein, family 5 DNQ11_09760 ENOG41068WN DNQ11_09780 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) DNQ11_09785 ENOG4105C72 UPF0176 protein DNQ11_09795 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DNQ11_09830 ENOG4107RHR regulatoR DNQ11_09840 ENOG4105D9N nucleoside DNQ11_09845 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DNQ11_09880 ENOG4107RAQ aminopeptidase DNQ11_09885 ENOG4107STQ Multicopper oxidase DNQ11_09930 ENOG4108T5E Copper resistance protein DNQ11_09935 ENOG4105KTB nuclear export factor GLE1 DNQ11_09945 ENOG4107RT3 EamA-like transporter family DNQ11_09950 ENOG4105GZI Transcriptional regulator DNQ11_09955 ENOG4108Z40 Transcriptional regulator DNQ11_09960 ENOG4107ZXU DSBA oxidoreductase DNQ11_09965 ENOG4108TVJ Nitroreductase DNQ11_09975 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DNQ11_09980 ENOG4106F5Q Membrane DNQ11_09985 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DNQ11_09995 ENOG4105CKI cobalamin synthesis protein DNQ11_10015 ENOG4108Z7G MaoC domain protein dehydratase DNQ11_10020 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DNQ11_10035 ENOG4105C0Z ABC transporter DNQ11_10040 ENOG4108IV0 ABC, transporter DNQ11_10045 ENOG4105C32 Amino acid ABC transporter (Permease) DNQ11_10055 ENOG4105SKE transcriptional Regulator LysR family DNQ11_10075 ENOG4105YGB Transcriptional regulator DNQ11_10085 ENOG4105C4M (Ubiquinol oxidase) subunit I DNQ11_10090 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DNQ11_10095 ENOG4108JJ9 ABC, transporter DNQ11_10100 ENOG4108JJ8 (ABC) transporter DNQ11_10150 ENOG4105EFI regulatoR DNQ11_10155 ENOG4105BZU Histidine kinase DNQ11_10175 ENOG41075D4 Aminoglycoside 6-adenylyltransferase DNQ11_10180 ENOG4108ZJ4 polysaccharide deacetylase DNQ11_10205 ENOG4105D6E homoserine dehydrogenase DNQ11_10230 ENOG4108KGH TRANSCRIPTIONal DNQ11_10240 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_10245 ENOG4105BZU Histidine kinase DNQ11_10250 ENOG4107VMI polysaccharide deacetylase DNQ11_10260 ENOG4105KT7 mgtC SapB transporter DNQ11_10265 ENOG4105VRR gCN5-related N-acetyltransferase DNQ11_10275 ENOG4105DUU IucA IucC family protein DNQ11_10280 ENOG4105CEY Amp-dependent synthetase and ligase DNQ11_10295 ENOG4108WBH protein TIM barrel DNQ11_10300 ENOG4105YWU small acid-soluble spore protein DNQ11_10310 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DNQ11_10365 ENOG4105KRN Transcriptional regulator, abrb family DNQ11_10375 ENOG4105YVS arsR family transcriptional regulator DNQ11_10380 ENOG4107SET aldo keto reductase DNQ11_10390 ENOG4107XZQ multidrug resistance protein DNQ11_10415 ENOG4105C8Q Methyl-accepting chemotaxis DNQ11_10435 ENOG4108K88 Membrane DNQ11_10440 ENOG4108WPJ Ferritin-like domain DNQ11_10455 ENOG4105DEN Luciferase family DNQ11_10475 ENOG4107QM2 Aldo Keto reductase DNQ11_10480 ENOG4105CKI cobalamin synthesis protein DNQ11_10565 ENOG4105DSE periplasmic solute binding protein DNQ11_10575 ENOG4105K4T epimerase DNQ11_10585 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DNQ11_10610 ENOG4105CVJ phosphoglycerate mutase DNQ11_10630 ENOG4107T5V SNARE associated Golgi DNQ11_10645 ENOG4108PJD permease DNQ11_10655 ENOG4108S4H thioesterase Superfamily protein DNQ11_10665 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DNQ11_10685 ENOG4105SXS Protein of unknown function (DUF456) DNQ11_10690 ENOG4105C37 (CBS) domain DNQ11_10710 ENOG4108Z7R Chaperone CsaA DNQ11_10730 ENOG4108ZRV stage ii sporulation protein p DNQ11_10740 ENOG4108VXD carboxy-peptidase DNQ11_10750 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DNQ11_10775 ENOG4108X4Q Hydrolase DNQ11_10785 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DNQ11_10790 ENOG4107RBS Methyltransferase DNQ11_10805 ENOG41087PP glycosyltransferase MGT family DNQ11_10810 ENOG4108JYZ YitT family DNQ11_10815 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DNQ11_10845 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DNQ11_10905 ENOG4105KBJ sporulation protein ytfj DNQ11_10930 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DNQ11_10950 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) DNQ11_10955 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_10965 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DNQ11_10970 ENOG4105EMN RNA polymerase sigma factor DNQ11_10995 ENOG4108V06 Glutathione peroxidase DNQ11_11010 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DNQ11_11030 ENOG4108IUE nitrate reductase beta subunit DNQ11_11035 ENOG4105R3A Nitrate reductase DNQ11_11060 ENOG4107V6Q Cyclic nucleotide-binding domain DNQ11_11065 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DNQ11_11070 ENOG4105D06 uba thif-type nad fad binding protein DNQ11_11075 ENOG4105CVM Molybdenum cofactor synthesis domain protein DNQ11_11080 ENOG4108ZAF Molybdopterin DNQ11_11110 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein DNQ11_11115 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DNQ11_11120 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DNQ11_11125 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DNQ11_11130 ENOG4108IFG nitrite reductase, (NAD(P)H) DNQ11_11135 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) DNQ11_11170 ENOG4105MCT stage V sporulation protein S DNQ11_11190 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DNQ11_11210 ENOG4105C5H ABC transporter DNQ11_11225 ENOG4108UUM single-stranded DNA-binding protein DNQ11_11255 ENOG4107YX5 Pfam:DUF548 DNQ11_11260 ENOG4105C75 arginyL-tRNA synthetase DNQ11_11285 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DNQ11_11305 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DNQ11_11310 ENOG4105C5S asparaginyl-tRNA synthetase DNQ11_11330 ENOG4105EC2 ftsk spoIIIe DNQ11_11425 ENOG4105BZW Glycerate kinase DNQ11_11430 ENOG4107QPK )-transporter DNQ11_11435 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_11440 ENOG41062D9 Histidine kinase DNQ11_11455 ENOG4105C8J )-transporter DNQ11_11475 ENOG4107XGZ Hydrolase DNQ11_11480 ENOG4105CY2 Citrate transporter DNQ11_11485 ENOG4105C0A alcohol dehydrogenase DNQ11_11500 ENOG4105KD7 acetyltransferase DNQ11_11530 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 DNQ11_11550 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) DNQ11_11565 ENOG4107RVG penicillin-binding protein DNQ11_11570 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DNQ11_11575 ENOG4105E9Q Acyl-transferase DNQ11_11580 ENOG4108UT2 hemolysin iii DNQ11_11590 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DNQ11_11605 ENOG4108RCR degv family DNQ11_11610 ENOG4105E8R UPF0173 metal-dependent hydrolase DNQ11_11615 ENOG4108KF3 Electron transport protein SCO1 SenC DNQ11_11620 ENOG4107Y70 Heat shock protein DNQ11_11625 ENOG4105CAQ asparagine synthetase DNQ11_11645 ENOG4108MES Periplasmic binding protein DNQ11_11650 ENOG4105F0I Aminotransferase DNQ11_11685 ENOG4105D8X mechanosensitive ion channel DNQ11_11690 ENOG4105BZU Histidine kinase DNQ11_11695 ENOG4105WH1 Two component transcriptional regulator luxr family DNQ11_11730 ENOG4105CMG Carbohydrate kinase DNQ11_11735 ENOG4105CMG Carbohydrate kinase DNQ11_11765 ENOG4108IJ8 ABC transporter DNQ11_11770 ENOG4105E90 ABC transporter DNQ11_11805 ENOG4105C37 (CBS) domain DNQ11_11835 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DNQ11_11850 ENOG4107S4Y M20 DapE family protein YgeY DNQ11_11855 ENOG4108TSC N-acetyltransferase DNQ11_11860 ENOG4108JUB Transcriptional regulator DNQ11_11870 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DNQ11_11910 ENOG4108N23 SpoOM-related protein DNQ11_11915 ENOG410841Q phosphoesterase PA-phosphatase related protein DNQ11_11925 ENOG4105SZ6 Thioredoxin DNQ11_11940 ENOG4108IBT Inherit from COG: transposase DNQ11_12070 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DNQ11_12110 ENOG4105BZ4 penicillin-binding protein DNQ11_12115 ENOG4105CZM Major Facilitator DNQ11_12120 ENOG4105W8X HesB YadR YfhF-family protein DNQ11_12130 ENOG4105DXD 2-methylcitrate dehydratase DNQ11_12135 ENOG4105CR4 methylisocitrate lyase DNQ11_12140 ENOG4105C1G acyl-Coa dehydrogenase DNQ11_12145 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DNQ11_12155 ENOG4105N14 lysine exporter protein LysE YggA DNQ11_12160 ENOG4105E39 Enoyl-CoA hydratase DNQ11_12175 ENOG4107RFY SbcCD D subunit DNQ11_12180 ENOG4105EYH Exonuclease DNQ11_12215 ENOG4105FCD Major Facilitator DNQ11_12225 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DNQ11_12230 ENOG4105E4F Isochorismate synthase DNQ11_12235 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase DNQ11_12240 ENOG4105WQI isochorismatase DNQ11_12245 ENOG4105CEY Amp-dependent synthetase and ligase DNQ11_12250 ENOG4105WQT MbtH domain protein DNQ11_12255 ENOG4105C0R drug resistance transporter emrb qaca subfamily DNQ11_12270 ENOG4105K70 DNA-binding protein DNQ11_12290 ENOG4105BZG amino acid carrier protein DNQ11_12310 ENOG4105FE9 pseudouridine synthase DNQ11_12315 ENOG4105C22 threonyL-tRNA synthetase DNQ11_12335 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DNQ11_12360 ENOG4108D32 Methyltransferase DNQ11_12390 ENOG41081I9 integral membrane protein DNQ11_12405 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DNQ11_12415 ENOG4105EYF MMPL domain protein DNQ11_12440 ENOG4105WCN acetyltransferase DNQ11_12470 ENOG4105C1Q protoporphyrinogen oxidase DNQ11_12480 ENOG41068WN DNQ11_12490 ENOG4105VEQ Cold shock protein DNQ11_12510 ENOG410667J hydrolase DNQ11_12560 ENOG4107V2S Transcriptional regulator DNQ11_12565 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DNQ11_12580 ENOG4105DND Transcriptional regulator DNQ11_12585 ENOG4108RPX mosc domain containing protein DNQ11_12600 ENOG4105BZ1 (ABC) transporter DNQ11_12605 ENOG4105BZ1 (ABC) transporter DNQ11_12625 ENOG4108JCI Transcriptional regulator DNQ11_12655 ENOG4108KPJ rna polymerase sigma factor DNQ11_12685 ENOG4105F32 YngK protein DNQ11_12715 ENOG4105RD7 BadF BadG BcrA BcrD DNQ11_12725 ENOG4107STF Involved in phosphonate degradation (By similarity) DNQ11_12755 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DNQ11_12770 ENOG4105C1J atp-dependent rna helicase DNQ11_12785 ENOG4108RZE Tetr family transcriptional regulator DNQ11_12805 ENOG41088CC tellurite resistance protein tehB DNQ11_12815 ENOG4108I0C methyltransferase DNQ11_12820 ENOG4107RA9 decarboxylase DNQ11_12825 ENOG41090HR transcriptional regulator DNQ11_12875 ENOG4105CIN aminoacyl-histidine dipeptidase DNQ11_12905 ENOG4107RF6 penicillin-binding protein DNQ11_12920 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DNQ11_12925 ENOG4105ETE Transcriptional regulator (LacI family DNQ11_12930 ENOG4105IE8 Alpha-ketoglutarate permease DNQ11_12935 ENOG4105CK5 oxidoreductase DNQ11_12960 ENOG4105D2N Aldolase DNQ11_12965 ENOG4105DH8 myo-inositol catabolism DNQ11_12995 ENOG4105VZ8 Transcriptional regulator DNQ11_13010 ENOG4108VXD carboxy-peptidase DNQ11_13030 ENOG41067SE Tetr family transcriptional regulator DNQ11_13035 ENOG4105C5H ABC transporter DNQ11_13045 ENOG4105BZU Histidine kinase DNQ11_13060 ENOG4106ANW SMI1_KNR4 DNQ11_13065 ENOG4105CEP NADH dehydrogenase DNQ11_13070 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) DNQ11_13085 ENOG4105CJ1 ABC, transporter DNQ11_13095 ENOG4107Z3H Transcriptional regulator, TetR family DNQ11_13115 ENOG4105C1G acyl-Coa dehydrogenase DNQ11_13120 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DNQ11_13125 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit DNQ11_13130 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DNQ11_13135 ENOG4105E39 Enoyl-CoA hydratase DNQ11_13140 ENOG4107QX3 carboxylase DNQ11_13145 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DNQ11_13155 ENOG4105WCN acetyltransferase DNQ11_13160 ENOG4105DBI uridine monophosphokinase DNQ11_13175 ENOG4105DZ1 carboxypeptidase DNQ11_13190 ENOG4105T9C HD domain DNQ11_13200 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DNQ11_13240 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DNQ11_13240 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DNQ11_13255 ENOG4105FQP Beta-lactamase DNQ11_13265 ENOG4107Y80 Major Facilitator superfamily DNQ11_13285 ENOG4105CUV Homoserine Kinase DNQ11_13320 ENOG4105CPQ Dehydrogenase DNQ11_13435 ENOG4105ETU transcriptional activator (TenA DNQ11_13565 ENOG410667J hydrolase DNQ11_13575 ENOG4105BZU Histidine kinase DNQ11_13580 ENOG4107RF6 penicillin-binding protein DNQ11_13600 ENOG4108JJB ABC transporter DNQ11_13615 ENOG4108HGU Histidine kinase DNQ11_13630 ENOG4105CB2 alcohol dehydrogenase DNQ11_13635 ENOG4105CJN penicillin-binding protein DNQ11_13645 ENOG4105FQP Beta-lactamase DNQ11_13680 ENOG4108V4B ThiJ pfpI DNQ11_13720 ENOG4107Y80 Major Facilitator superfamily DNQ11_13740 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DNQ11_13760 ENOG4107Y9U Membrane DNQ11_13800 ENOG4105FCD Major Facilitator DNQ11_13815 ENOG4105E09 nadh pyrophosphatase DNQ11_13820 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DNQ11_13825 ENOG4108Z4K mutator MutT protein DNQ11_13860 ENOG4108XI2 Domain of unknown function (DUF1963) DNQ11_13895 ENOG4105KWG Pfam:DUF1696 DNQ11_13930 ENOG4105PKS Excinuclease abc c subunit domain protein DNQ11_13975 ENOG4107VFR oxidoreductase DNQ11_14000 ENOG4105PAD Hydrolase DNQ11_14020 ENOG4105DY8 decarboxylase DNQ11_14035 ENOG4108IUM Glycogen debranching enzyme DNQ11_14060 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DNQ11_14070 ENOG4105FDR Membrane DNQ11_14105 ENOG4108V3A UPF0421 protein DNQ11_14125 ENOG4105MSI germination protein ypeb DNQ11_14145 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) DNQ11_14150 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) DNQ11_14155 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) DNQ11_14160 ENOG4107Z3H Transcriptional regulator, TetR family DNQ11_14195 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family DNQ11_14215 ENOG4105E98 transcriptional regulator DeoR family DNQ11_14235 ENOG41062ES Transcriptional regulator DNQ11_14260 ENOG4107QKR Dehydrogenase DNQ11_14270 ENOG4107RUY (E1 component), alpha subunit DNQ11_14280 ENOG4105E1F short-chain dehydrogenase reductase DNQ11_14285 ENOG4105RHY Pfam:UPF0157 DNQ11_14320 ENOG4107SQ8 Glycine betaine DNQ11_14325 ENOG4108IJ7 Glycine betaine DNQ11_14350 ENOG4105E66 phosphoriboisomerase A DNQ11_14355 ENOG41082BV acetyltransferase DNQ11_14360 ENOG4108M1A Chitin-binding protein DNQ11_14405 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DNQ11_14455 ENOG4105EEM helicase DNQ11_14475 ENOG4105C9U ATP-dependent DNA helicase RecQ DNQ11_14530 ENOG4108M1A Chitin-binding protein DNQ11_14550 ENOG4105BZG amino acid carrier protein DNQ11_14555 ENOG4105C26 Dehydrogenase DNQ11_14560 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DNQ11_14565 ENOG4105CTU Proline racemase DNQ11_14570 ENOG4105CTU Proline racemase DNQ11_14575 ENOG41080HI glycine oxidase DNQ11_14615 ENOG4107T5V SNARE associated Golgi DNQ11_14630 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DNQ11_14635 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DNQ11_14650 ENOG4105DTQ mandelate racemase muconate lactonizing DNQ11_14705 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) DNQ11_14710 ENOG4105BZU Histidine kinase DNQ11_14750 ENOG4105DPN Oligoendopeptidase f DNQ11_14765 ENOG4105EPR degv family DNQ11_14810 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DNQ11_14815 ENOG4106K7D Major facilitator family transporter DNQ11_14835 ENOG4107BMA Transglycosylase associated protein DNQ11_14850 ENOG41089UC methyltransferase, type 11 DNQ11_14890 ENOG4105CHM Aminotransferase DNQ11_14920 ENOG4105DVE abc transporter atp-binding protein DNQ11_14970 ENOG4105C02 permease DNQ11_14985 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DNQ11_14990 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DNQ11_14995 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein DNQ11_15020 ENOG4105E09 nadh pyrophosphatase DNQ11_15040 ENOG4108AQF aminoglycoside N(3)-acetyltransferase DNQ11_15095 ENOG4107VC0 DNA alkylation repair enzyme DNQ11_15110 ENOG4107VMI polysaccharide deacetylase DNQ11_15120 ENOG4108ZCF integral membrane protein DNQ11_15125 ENOG4105E0M Sulfatase DNQ11_15135 ENOG4105C5H ABC transporter DNQ11_15145 ENOG4105EYF MMPL domain protein DNQ11_15150 ENOG4105EYF MMPL domain protein DNQ11_15155 ENOG4105EYF MMPL domain protein DNQ11_15160 ENOG41082JN Transcriptional regulator DNQ11_15180 ENOG4105CIH Imidazole acetol-phosphate transaminase DNQ11_15185 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase DNQ11_15195 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DNQ11_15240 ENOG41069ER domain protein DNQ11_15255 ENOG4105EMN RNA polymerase sigma factor DNQ11_15280 ENOG4105D4B ABC, transporter DNQ11_15290 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane DNQ11_15300 ENOG4105DKT Transcriptional regulator DNQ11_15315 ENOG41061GT Aldolase DNQ11_15335 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) DNQ11_15365 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DNQ11_15375 ENOG4105II7 pyrroline-5-carboxylate reductase DNQ11_15385 ENOG4107258 Transcriptional regulator DNQ11_15400 ENOG4105E0Y RtcB Protein DNQ11_15405 ENOG4105ECK Fatty Acid Desaturase DNQ11_15410 ENOG4105G6Z alkaline phosphatase DNQ11_15420 ENOG4105VMP Transcriptional regulator DNQ11_15435 ENOG41090T1 Membrane DNQ11_15445 ENOG4108WCX response regulator DNQ11_15455 ENOG41068WN DNQ11_15480 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DNQ11_15505 ENOG4105CKK Glycosyl transferase, family 2 DNQ11_15530 ENOG4105CKK Glycosyl transferase, family 2 DNQ11_15540 ENOG4105C8Y Acetylornithine aminotransferase DNQ11_15580 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DNQ11_15590 ENOG4108TVJ Nitroreductase DNQ11_15595 ENOG4105FS7 Transcriptional regulator DNQ11_15635 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DNQ11_15650 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DNQ11_15680 ENOG4108XET gCN5-related N-acetyltransferase DNQ11_15760 ENOG410635A Membrane DNQ11_15765 ENOG4105KNA -acetyltransferase DNQ11_15770 ENOG4108IQI permease DNQ11_15780 ENOG4105F1N DNA alkylation repair DNQ11_15820 ENOG4107RF6 penicillin-binding protein DNQ11_15830 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DNQ11_15875 ENOG4105P4J Allophanate hydrolase, subunit 1 DNQ11_15880 ENOG4107258 Transcriptional regulator DNQ11_15890 ENOG4106N3A copper homeostasis protein cutc DNQ11_15895 ENOG4108ZRV stage ii sporulation protein p DNQ11_15900 ENOG4108ZHR arsR family transcriptional regulator DNQ11_15910 ENOG4105FDT acyl-CoA dehydrogenase DNQ11_15930 ENOG4105DWD nucleoside recognition domain protein DNQ11_15960 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) DNQ11_16035 ENOG4105E2A Dehydrogenase DNQ11_16050 ENOG4108IJ0 Aspartate ammonia-lyase DNQ11_16055 ENOG4105HDK L-asparaginase DNQ11_16060 ENOG4108IMY Transcriptional regulator DNQ11_16070 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) DNQ11_16075 ENOG4105CUB amino acid DNQ11_16085 ENOG4105II7 pyrroline-5-carboxylate reductase DNQ11_16095 ENOG4105C6K Malic enzyme DNQ11_16110 ENOG4108Q8B Spore germination protein DNQ11_16135 ENOG4105CSV Glutaminase DNQ11_16175 ENOG4105CH6 catalase DNQ11_16185 ENOG4105CHJ isochorismatase hydrolase DNQ11_16215 ENOG41090MY MarR family Transcriptional regulator DNQ11_16255 ENOG4108606 TspO/MBR family DNQ11_16260 ENOG4105CVP deoxyribo-dipyrimidine photolyase DNQ11_16275 ENOG4108TWJ NADH dehydrogenase subunit 5 DNQ11_16280 ENOG4105GPN Uncharacterized conserved protein (DUF2294) DNQ11_16300 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DNQ11_16305 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) DNQ11_16315 ENOG4105DSE periplasmic solute binding protein DNQ11_16320 ENOG4105CC5 ABC transporter DNQ11_16325 ENOG4105DIK (ABC) transporter DNQ11_16355 ENOG4105D6J arsenicaL-resistance protein DNQ11_16360 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_16365 ENOG41085FC arsR family transcriptional regulator DNQ11_16380 ENOG4105F7F Chaperone DNQ11_16395 ENOG4105CHR reductase DNQ11_16400 ENOG4108YXU transcriptional regulator AsnC family DNQ11_16480 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DNQ11_16490 ENOG4105C0R drug resistance transporter emrb qaca subfamily DNQ11_16505 ENOG4105IIP Membrane DNQ11_16520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_16525 ENOG41062D9 Histidine kinase DNQ11_16560 ENOG4105K6H D-cysteine desulfhydrase DNQ11_16590 ENOG4105VZ8 Transcriptional regulator DNQ11_16605 ENOG4108NNI Beta-lactamase domain-containing protein DNQ11_16610 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase DNQ11_16620 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DNQ11_16625 ENOG4105JQZ Methyltransferase DNQ11_16640 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DNQ11_16645 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) DNQ11_16660 ENOG4105BZU Histidine kinase DNQ11_16675 ENOG4108U05 Transcriptional regulator DNQ11_16690 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DNQ11_16695 ENOG4105DJB Major Facilitator Superfamily DNQ11_16700 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) DNQ11_16705 ENOG4107QR9 Iron-sulfur cluster binding protein DNQ11_16715 ENOG4106P55 Transcriptional regulator DNQ11_16725 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DNQ11_16765 ENOG4105TRI Hydrolase DNQ11_16800 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DNQ11_16830 ENOG4107QJQ Mate efflux family protein DNQ11_16850 ENOG4105MZU cell filamentation protein DNQ11_16855 ENOG4105EQ0 Major Facilitator superfamily DNQ11_16860 ENOG4108JGH Tetr family transcriptional regulator DNQ11_16875 ENOG4105C44 Serine transporter DNQ11_16880 ENOG4105EJQ L-serine dehydratase DNQ11_16900 ENOG4108JPW Aminotransferase DNQ11_16915 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) DNQ11_16925 ENOG4105DVH amino acid DNQ11_16945 ENOG4108JQ1 Dehydrogenase DNQ11_16965 ENOG4108AEY RNA polymerase sigma factor DNQ11_16980 ENOG41082W1 Cupin 2, conserved barrel domain protein DNQ11_16990 ENOG410874W AraC family transcriptional regulator DNQ11_17045 ENOG4108ISG Major Facilitator DNQ11_17055 ENOG4107MII Sugar-specific transcriptional regulator TrmB DNQ11_17060 ENOG4105CZM Major Facilitator DNQ11_17085 ENOG41069JR DNQ11_17095 ENOG4105RXJ DNQ11_17100 ENOG4105KPY Small multidrug resistance protein DNQ11_17105 ENOG4105KBX Transcriptional regulator, TetR family DNQ11_17115 ENOG4105CRW Short chain fatty acid transporter DNQ11_17125 ENOG4105DYS nad(p)h dehydrogenase (quinone) DNQ11_17155 ENOG4108JJB ABC transporter DNQ11_17160 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DNQ11_17185 ENOG4108K8S endonuclease I DNQ11_17200 ENOG41067QW Transcriptional regulator DNQ11_17210 ENOG4108Z66 YbaK ebsC protein DNQ11_17215 ENOG4105CUT histidyl-tRNA synthetase DNQ11_17230 ENOG4105KVH Transcriptional regulator DNQ11_17235 ENOG4108RCM Nitroreductase DNQ11_17260 ENOG4108PSK reductase DNQ11_17270 ENOG4105CJ1 ABC, transporter DNQ11_17330 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_17335 ENOG4105DKQ ROK family DNQ11_17340 ENOG4106UW1 Major Facilitator superfamily DNQ11_17345 ENOG4108UW5 maltose o-acetyltransferase DNQ11_17355 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DNQ11_17365 ENOG4105C31 Tryptophanyl-tRNA synthetase DNQ11_17370 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DNQ11_17395 ENOG4105DMQ Methyltransferase DNQ11_17405 ENOG4105EV4 Multidrug resistance protein mdtH DNQ11_17435 ENOG4105C37 (CBS) domain DNQ11_17450 ENOG4105DDN Pentapeptide repeat-containing protein DNQ11_17455 ENOG4105XDF Protein of unknown function (DUF1272) DNQ11_17465 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) DNQ11_17470 ENOG4105CMG Carbohydrate kinase DNQ11_17475 ENOG4105C6Z Gluconate DNQ11_17480 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DNQ11_17495 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DNQ11_17500 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DNQ11_17505 ENOG4105CIS alcohol dehydrogenase DNQ11_17510 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone DNQ11_17530 ENOG4105EWI Short-chain dehydrogenase reductase Sdr DNQ11_17535 ENOG4105D4Y metalloprotease DNQ11_17555 ENOG4105CV8 reductase DNQ11_17560 ENOG4105F27 Major Facilitator DNQ11_17580 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) DNQ11_17585 ENOG4105C44 Serine transporter DNQ11_17620 ENOG4105KVH Transcriptional regulator DNQ11_17625 ENOG4108TZY GntR Family Transcriptional Regulator DNQ11_17635 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DNQ11_17640 ENOG4105KVH Transcriptional regulator DNQ11_17645 ENOG4105KVH Transcriptional regulator DNQ11_17680 ENOG4105JAB phenazine biosynthesis protein, phzf family DNQ11_17690 ENOG4105CHR reductase DNQ11_17710 ENOG4105KVH Transcriptional regulator DNQ11_17780 ENOG4105KAF membrAne DNQ11_17810 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) DNQ11_17830 ENOG4107YXZ hydrolase, family 25 DNQ11_17855 ENOG4105ED2 Beta-lactamase DNQ11_17865 ENOG4105H3G oxidoreductase DNQ11_17900 ENOG4105CIS alcohol dehydrogenase DNQ11_17940 ENOG4108TN2 lmbE family DNQ11_17950 ENOG4107R3E Citrate transporter DNQ11_17980 ENOG4105EHG Permease protein DNQ11_17985 ENOG4105DQ5 transport system permease protein DNQ11_17990 ENOG4105NX3 Membrane DNQ11_17995 ENOG4107ZY0 Phenazine biosynthesis-like protein DNQ11_18015 ENOG4107CUJ Protein of unknown function (DUF2690) DNQ11_18025 ENOG4107V2S Transcriptional regulator DNQ11_18045 ENOG4105C98 muts2 protein DNQ11_18055 ENOG4105E5K Alpha-amylase DNQ11_18070 ENOG4108A04 Beta-lactamase DNQ11_18100 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DNQ11_18125 ENOG41082BM Transcriptional regulator, arsr family DNQ11_18130 ENOG4105CIS alcohol dehydrogenase DNQ11_18155 ENOG4105RHY Pfam:UPF0157 DNQ11_18165 ENOG4105C09 Bile acid DNQ11_18170 ENOG4105CQB FAD linked oxidase domain protein DNQ11_18200 ENOG4108UT6 Transferase hexapeptide repeat containing protein DNQ11_18215 ENOG4105E39 Enoyl-CoA hydratase DNQ11_18225 ENOG4105KT7 mgtC SapB transporter DNQ11_18240 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_18245 ENOG41073R8 VanW family DNQ11_18255 ENOG4108R1P DNQ11_18275 ENOG4105VEQ Cold shock protein DNQ11_18295 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DNQ11_18315 ENOG410904N short-chain dehydrogenase reductase DNQ11_18325 ENOG4106IQC argininosuccinate lyase DNQ11_18340 ENOG4108IA2 Sodium pantothenate symporter DNQ11_18350 ENOG4105C26 Dehydrogenase DNQ11_18355 ENOG4105CHR reductase DNQ11_18365 ENOG4105EWU Squalene--hopene cyclase DNQ11_18375 ENOG4105FR1 rard protein DNQ11_18380 ENOG410696E Membrane DNQ11_18395 ENOG4105D1F ATP-binding protein DNQ11_18405 ENOG4108ZAF Molybdopterin DNQ11_18410 ENOG4105CVM Molybdenum cofactor synthesis domain protein DNQ11_18415 ENOG4105D06 uba thif-type nad fad binding protein DNQ11_18420 ENOG4105TMB Formate nitrite transporter DNQ11_18435 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DNQ11_18440 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) DNQ11_18450 ENOG4108JB9 formate dehydrogenase DNQ11_18460 ENOG4105E1K spore germination protein DNQ11_18520 ENOG4107QJT sodium dicarboxylate symporter DNQ11_18525 ENOG4108KGH TRANSCRIPTIONal DNQ11_18535 ENOG4105EMN RNA polymerase sigma factor DNQ11_18555 ENOG4105CIG ABC transporter DNQ11_18565 ENOG4105D9R oxidoreductase DNQ11_18575 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DNQ11_18585 ENOG4105K4P CoA-binding domain protein DNQ11_18590 ENOG4105C0H protease DNQ11_18595 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_18605 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase DNQ11_18610 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DNQ11_18615 ENOG4105W8X HesB YadR YfhF-family protein DNQ11_18645 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DNQ11_18655 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DNQ11_18665 ENOG4108JJA ABC, transporter DNQ11_18670 ENOG4108I0Z Aconitate hydratase DNQ11_18710 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DNQ11_18730 ENOG4107F3J Amp-dependent synthetase and ligase DNQ11_18735 ENOG4107ZYJ bioY protein DNQ11_18740 ENOG4105CEY Amp-dependent synthetase and ligase DNQ11_18795 ENOG4107AYK membrAne DNQ11_18810 ENOG4105BZU Histidine kinase DNQ11_18815 ENOG4105FBA Phospholipase Carboxylesterase DNQ11_18820 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase DNQ11_18825 ENOG4105CK7 Sodium proline symporter DNQ11_18830 ENOG4105CBC glutamate synthase DNQ11_18835 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DNQ11_18840 ENOG4108VJ1 Transcriptional regulator (CarD family DNQ11_18845 ENOG4108903 Formimidoylglutamase DNQ11_18870 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) DNQ11_18935 ENOG4107QIV Cytochrome c biogenesis protein DNQ11_18950 ENOG4107RSM transcriptional regulator DNQ11_18955 ENOG4105VAW lrga family DNQ11_18960 ENOG41067MG lrgb family DNQ11_18985 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DNQ11_19000 ENOG4105BZ1 (ABC) transporter DNQ11_19005 ENOG4105BZ1 (ABC) transporter DNQ11_19030 ENOG4105D7V transposase DNQ11_19050 ENOG4105D5T phosphonate abc transporter DNQ11_19070 ENOG4108SVB resolvase DNQ11_19090 ENOG4105K7K Transcriptional regulator DNQ11_19135 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase DNQ11_19140 ENOG4105XSJ toxin secretion phage lysis holin DNQ11_19345 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) DNQ11_19460 ENOG4105C5F glutamine synthetase DNQ11_19465 ENOG4105KV4 Transcriptional regulator DNQ11_19470 ENOG4105CXI aluminum resistance protein DNQ11_19480 ENOG4105EN6 Membrane DNQ11_19490 ENOG4106F1P AAA ATPase, central domain protein DNQ11_19520 ENOG41069ER domain protein DNQ11_19530 ENOG4105DM4 PTS System DNQ11_19535 ENOG4105DE4 1-phosphofructokinase DNQ11_19540 ENOG4105E98 transcriptional regulator DeoR family DNQ11_19550 ENOG4108SJC Membrane DNQ11_19590 ENOG4105TMB Formate nitrite transporter DNQ11_19595 ENOG4105K70 DNA-binding protein DNQ11_19605 ENOG4105C59 p-type ATPase DNQ11_19610 ENOG410681U heavy metal transport detoxification protein DNQ11_19615 ENOG4105VPX protein, conserved in bacteria DNQ11_19625 ENOG4105NIV Esterase DNQ11_19630 ENOG4105E0A ABC, transporter DNQ11_19650 ENOG4105CGK Exodeoxyribonuclease III DNQ11_19660 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DNQ11_19665 ENOG4105D03 DNA-3-methyladenine glycosylase II DNQ11_19695 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_19700 ENOG4105BZU Histidine kinase DNQ11_19720 ENOG41067MG lrgb family DNQ11_19735 ENOG4107TTQ Alpha beta hydrolase fold DNQ11_19740 ENOG4107YEI lmbE family DNQ11_19765 ENOG4105F0V Cell wall hydrolase DNQ11_19770 ENOG4107R6R udp-galactopyranose mutase DNQ11_19775 ENOG4105E0M Sulfatase DNQ11_19790 ENOG4107QHE Choloylglycine hydrolase DNQ11_19815 ENOG4105DA5 (ABC) transporter DNQ11_19840 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DNQ11_19845 ENOG4105DQU oxidoreductase, subunit beta DNQ11_19850 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein DNQ11_19855 ENOG4108IGT Dipeptidase DNQ11_19860 ENOG4105MCT stage V sporulation protein S DNQ11_19865 ENOG4105D48 metallophosphoesterase DNQ11_19890 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DNQ11_19905 ENOG4105XZV Protein of unknown function (DUF3243) DNQ11_19910 ENOG4108RKS Short-chain dehydrogenase reductase Sdr DNQ11_19935 ENOG4108JQ9 ABC transporter DNQ11_19940 ENOG4105DIH basic membrane DNQ11_19945 ENOG4105FDP GntR family transcriptional regulator DNQ11_19950 ENOG4107QZI cell division protein FtsK DNQ11_19960 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit DNQ11_19975 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DNQ11_19985 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DNQ11_19990 ENOG4108S0H Dipicolinic acid synthetase, b subunit DNQ11_19995 ENOG4105E35 Dipicolinate synthase subunit A DNQ11_20010 ENOG4105C1V Peptidase, M16 DNQ11_20030 ENOG4105DTN riboflavin biosynthesis protein ribF DNQ11_20035 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DNQ11_20045 ENOG4105W7A Protein of unknown function (DUF503) DNQ11_20055 ENOG4105VHM ribosomal protein DNQ11_20060 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DNQ11_20065 ENOG4105CHV Transcription elongation factor NusA DNQ11_20075 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DNQ11_20090 ENOG4105DZP Membrane-associated zinc metalloprotease DNQ11_20095 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DNQ11_20100 ENOG4105KNE Phosphatidate cytidylyltransferase DNQ11_20105 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DNQ11_20145 ENOG4108HE4 integrase family DNQ11_20155 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DNQ11_20165 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DNQ11_20180 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) DNQ11_20205 ENOG4105VB6 UPF0109 protein DNQ11_20225 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DNQ11_20230 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DNQ11_20245 ENOG4105CHR reductase DNQ11_20250 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DNQ11_20265 ENOG4105CB5 ATP-dependent DNA helicase recG DNQ11_20270 ENOG4105DP4 dak2 domain fusion protein ylov DNQ11_20275 ENOG4108ZAA Alkaline-shock protein DNQ11_20290 ENOG4105FJ0 thiamine DNQ11_20295 ENOG4105DJV ribulose-phosphate 3-epimerase DNQ11_20300 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DNQ11_20305 ENOG4105D9P serine threonine protein kinase DNQ11_20310 ENOG4108ZF3 Phosphatase DNQ11_20320 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DNQ11_20330 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DNQ11_20335 ENOG4105C25 Primosomal protein n' DNQ11_20340 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DNQ11_20360 ENOG4105DSJ YicC domain protein DNQ11_20370 ENOG4105F23 Fibronectin-binding protein DNQ11_20375 ENOG4105DC7 peptidase M24 DNQ11_20435 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DNQ11_20460 ENOG4105C34 Pseudouridine synthase DNQ11_20475 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DNQ11_20485 ENOG4105DBK s4 domain protein DNQ11_20490 ENOG41067XK integral membrane protein DNQ11_20500 ENOG4105DFA alanine racemase domain protein DNQ11_20505 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DNQ11_20510 ENOG4105WR5 sporulation protein, YlmC YmxH family DNQ11_20520 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_20530 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DNQ11_20535 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DNQ11_20540 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) DNQ11_20545 ENOG4105D4A Cell wall formation (By similarity) DNQ11_20550 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DNQ11_20555 ENOG4105CNI cell division protein FtsW DNQ11_20570 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DNQ11_20575 ENOG4105CJN penicillin-binding protein DNQ11_20580 ENOG4105CJN penicillin-binding protein DNQ11_20585 ENOG41068DC Essential cell division protein (By similarity) DNQ11_20620 ENOG4105KNH Nucleic acid-binding protein DNQ11_20670 ENOG4105XSJ toxin secretion phage lysis holin DNQ11_20750 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DNQ11_20760 ENOG4105CAR Terminase, large subunit DNQ11_20860 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DNQ11_20875 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_20930 ENOG4108IMY Transcriptional regulator DNQ11_20970 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) DNQ11_20980 ENOG41063PX domain protein DNQ11_20985 ENOG4105D78 K07001 NTE family protein DNQ11_20990 ENOG4105H20 Sporulation integral membrane protein YlbJ DNQ11_21000 ENOG4106H78 methyltransferase DNQ11_21020 ENOG4107TB6 phosphoglycerate mutase DNQ11_21035 ENOG4106UY4 Inherit from COG: Scp-like extracellular DNQ11_21085 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DNQ11_21095 ENOG4105CNI cell division protein FtsW DNQ11_21110 ENOG4108IAB Phoh family DNQ11_21130 ENOG4105QA2 DNQ11_21135 ENOG4105CI3 gtp-binding protein typa DNQ11_21145 ENOG4105ECY inositol monophosphatase DNQ11_21165 ENOG4105CXN decarboxylase DNQ11_21210 ENOG4105C7S Dehydrogenase DNQ11_21215 ENOG4105CPP Dehydrogenase, E1 component DNQ11_21230 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DNQ11_21235 ENOG4108X4Q Hydrolase DNQ11_21250 ENOG4105CN5 Metallo-Beta-Lactamase DNQ11_21255 ENOG4107ZYR domain protein DNQ11_21290 ENOG4108XRC Protein of unknown function (DUF458) DNQ11_21300 ENOG4107IN1 Protein of unknown function (DUF1797) DNQ11_21315 ENOG4105EPM Diguanylate phosphodiesterase DNQ11_21320 ENOG4105K6S Short-chain dehydrogenase reductase Sdr DNQ11_21340 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) DNQ11_21350 ENOG4105UIN DNQ11_21415 ENOG4108HGU Histidine kinase DNQ11_21425 ENOG4105CHM Aminotransferase DNQ11_21430 ENOG4105FKQ transcriptional regulator DNQ11_21435 ENOG4105EG2 ABC transporter, permease DNQ11_21445 ENOG4107FKK extracellular solute-binding protein family 1 DNQ11_21455 ENOG4105CG3 alpha amylase, catalytic region DNQ11_21500 ENOG4105CHU acetyl-coa acetyltransferase DNQ11_21540 ENOG4105K7K Transcriptional regulator DNQ11_21545 ENOG4105DTD Dehydrogenase DNQ11_21555 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DNQ11_21565 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DNQ11_21590 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) DNQ11_21615 ENOG4106TD9 Diguanylate cyclase DNQ11_21635 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DNQ11_21650 ENOG4105CID antiterminator DNQ11_21660 ENOG4105FDP GntR family transcriptional regulator DNQ11_21670 ENOG4105CE4 GlcNAc 6-P deacetylase DNQ11_21715 ENOG4107ZE5 PPIases accelerate the folding of proteins DNQ11_21720 ENOG4105PTM secreted protein DNQ11_21725 ENOG4105J7I hydrolase DNQ11_21735 ENOG4105G6R Stage v sporulation protein ae DNQ11_21745 ENOG4105CZ3 stage V sporulation protein ad DNQ11_21750 ENOG41090VF Stage v sporulation protein ac DNQ11_21770 ENOG4105C8J )-transporter DNQ11_21775 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_21785 ENOG41082AN stage II sporulation protein DNQ11_21790 ENOG4105DZ1 carboxypeptidase DNQ11_21800 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DNQ11_21805 ENOG4105DVE abc transporter atp-binding protein DNQ11_21840 ENOG4105D7N magnesium and cobalt transport protein CorA DNQ11_21865 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DNQ11_21875 ENOG4105I3K Ferric uptake regulator, Fur family DNQ11_21880 ENOG4105MZ9 stage II sporulation protein m DNQ11_21900 ENOG4105CPC Aldo Keto reductase DNQ11_21910 ENOG4105RHY Pfam:UPF0157 DNQ11_21930 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DNQ11_21940 ENOG4105ETE Transcriptional regulator (LacI family DNQ11_21945 ENOG4108YM7 Gcn5-related n-acetyltransferase DNQ11_21965 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DNQ11_21970 ENOG4108R6K riboflavin synthase, subunit alpha DNQ11_21990 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) DNQ11_21995 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DNQ11_22000 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DNQ11_22005 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DNQ11_22015 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DNQ11_22030 ENOG4105DFD Na H antiporter DNQ11_22035 ENOG4105CGH 5'-nucleotidase DNQ11_22075 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DNQ11_22090 ENOG4108IXY short-chain dehydrogenase reductase DNQ11_22100 ENOG4105II7 pyrroline-5-carboxylate reductase DNQ11_22105 ENOG4105EJQ L-serine dehydratase DNQ11_22135 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DNQ11_22145 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DNQ11_22150 ENOG4105D9U N-acetyltransferase DNQ11_22165 ENOG4108VZI ErfK ybiS ycfS ynhG family protein DNQ11_22170 ENOG4108QEG Membrane DNQ11_22175 ENOG4105CDA abc transporter atp-binding protein DNQ11_22180 ENOG4105E5Q amino acid AbC transporter DNQ11_22185 ENOG4108HW3 (ABC) transporter DNQ11_22200 ENOG4105G7B Protein of unknown function (DUF2992) DNQ11_22205 ENOG4105E09 nadh pyrophosphatase DNQ11_22220 ENOG4105C7S Dehydrogenase DNQ11_22225 ENOG4105CPP Dehydrogenase, E1 component DNQ11_22245 ENOG4107RDP Dehydrogenase DNQ11_22260 ENOG4108JUB Transcriptional regulator DNQ11_22270 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DNQ11_22285 ENOG4107QQR Sporulation DNQ11_22295 ENOG4105S1Z Stage IV sporulation protein B DNQ11_22300 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DNQ11_22310 ENOG4105DX0 Hemolysin A DNQ11_22320 ENOG4105CTB Polyprenyl synthetase DNQ11_22345 ENOG4108ZSR alkaline shock protein DNQ11_22350 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DNQ11_22375 ENOG410644B Stage III sporulation protein af DNQ11_22385 ENOG4105KQ4 Stage iii sporulation protein ad DNQ11_22390 ENOG4108CQH stage III sporulation protein AC DNQ11_22395 ENOG4105KR5 Stage iii sporulation protein DNQ11_22400 ENOG4105CD2 stage iii sporulation protein aa DNQ11_22425 ENOG4105DC7 peptidase M24 DNQ11_22440 ENOG4105CBJ Metal-dependent enzyme DNQ11_22450 ENOG4107YBY Hydrolase DNQ11_22470 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) DNQ11_22475 ENOG4105WZW rhodanese family DNQ11_22495 ENOG41080TC multidrug resistance protein DNQ11_22535 ENOG4105CJ1 ABC, transporter DNQ11_22540 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DNQ11_22575 ENOG4105C0D helicase DNQ11_22700 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DNQ11_22705 ENOG4105C3R Methionine synthase DNQ11_22715 ENOG4105C28 cystathionine DNQ11_22720 ENOG4105C28 cystathionine DNQ11_22740 ENOG4105C5X domain protein DNQ11_22750 ENOG4105DKQ ROK family DNQ11_22760 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DNQ11_22775 ENOG4108UTW Plays a role in the regulation of phosphate uptake DNQ11_22780 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DNQ11_22785 ENOG4105E2Z phosphate ABC transporter (Permease DNQ11_22790 ENOG4105C8U phosphate abc transporter DNQ11_22795 ENOG4105PWN phosphate abc transporter DNQ11_22800 ENOG4107RF6 penicillin-binding protein DNQ11_22810 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DNQ11_22835 ENOG4105N80 Ferric uptake regulator, Fur family DNQ11_22845 ENOG4105FDK ABC transporter DNQ11_22850 ENOG4108JYZ YitT family DNQ11_22855 ENOG41069ZM Protein of unknown function (DUF2624) DNQ11_22880 ENOG4105EGD dinuclear metal center protein, YbgI family DNQ11_22895 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_22900 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DNQ11_22935 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DNQ11_22940 ENOG4105KG3 cytidine deaminase DNQ11_22945 ENOG4107YR5 Diacylglycerol kinase DNQ11_22955 ENOG4105CTJ Metal Dependent Phosphohydrolase DNQ11_22960 ENOG4105C9A Phoh family DNQ11_22975 ENOG41068P3 sporulation protein YqfC DNQ11_22980 ENOG4105KTH gatB Yqey DNQ11_22995 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DNQ11_23000 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DNQ11_23020 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ DNQ11_23030 ENOG4105CSA Coproporphyrinogen iii oxidase DNQ11_23035 ENOG4105KVH Transcriptional regulator DNQ11_23060 ENOG4105TQK DNA polymerase iii, delta' subunit DNQ11_23070 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DNQ11_23075 ENOG4108UK2 deaminase DNQ11_23080 ENOG4105KQC Competence protein DNQ11_23090 ENOG4105DXX methyltransferase DNQ11_23100 ENOG4108WF2 Metal Dependent Phosphohydrolase DNQ11_23110 ENOG410812S Rna-binding protein DNQ11_23120 ENOG4105CQW ribosome biogenesis GTPase YqeH DNQ11_23125 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DNQ11_23140 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_23165 ENOG4108TVJ Nitroreductase DNQ11_23180 ENOG4105G6Z alkaline phosphatase DNQ11_23190 ENOG4108MUZ hydrolase DNQ11_23225 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin DNQ11_23230 ENOG4105MIR Phenylalanine 4-monooxygenase DNQ11_23280 ENOG4105S6R Iron-hydroxamate transporter permease subunit DNQ11_23285 ENOG4108V5C ABC transporter DNQ11_23295 ENOG4108EKI Dehydrogenase DNQ11_23300 ENOG4105C28 cystathionine DNQ11_23330 ENOG4107XRG penicillin-binding protein DNQ11_23345 ENOG4105CFP Peptidase U32 DNQ11_23350 ENOG4105XYU peptidase (U32 family) DNQ11_23355 ENOG4108VQJ O-methyltransferase DNQ11_23360 ENOG4105HHA aminodeoxychorismate lyase DNQ11_23380 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DNQ11_23390 ENOG4105C02 permease DNQ11_23405 ENOG41060CR DNQ11_23410 ENOG4105C7H Helicase, RecD TraA family DNQ11_23420 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) DNQ11_23425 ENOG4105C3J Cysteine desulfurase DNQ11_23435 ENOG4105D1H recombination factor protein RarA DNQ11_23440 ENOG4108VCI transcription factor, rsfa family DNQ11_23445 ENOG4105CUZ uba thif-type nad fad binding protein DNQ11_23455 ENOG4105CUT histidyl-tRNA synthetase DNQ11_23475 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DNQ11_23485 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DNQ11_23490 ENOG41076HS cation diffusion facilitator family transporter DNQ11_23495 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DNQ11_23505 ENOG4105CKP Polysaccharide Biosynthesis Protein DNQ11_23510 ENOG4108QG2 Membrane DNQ11_23520 ENOG4105VIE preprotein translocase, subunit YajC DNQ11_23535 ENOG41061AI Protein of unknown function (DUF2905) DNQ11_23550 ENOG4108HUF Transporter DNQ11_23560 ENOG4108IPJ Membrane DNQ11_23565 ENOG4108IPJ Membrane DNQ11_23570 ENOG41082BM Transcriptional regulator, arsr family DNQ11_23595 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DNQ11_23600 ENOG4108IYU L-aspartate oxidase DNQ11_23615 ENOG4108RPX mosc domain containing protein DNQ11_23620 ENOG4105CQC Prephenate dehydratase DNQ11_23650 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control DNQ11_23665 ENOG4105X36 (ribosomal) protein DNQ11_23675 ENOG4105C03 ribonuclease DNQ11_23690 ENOG4107QMS site-determining protein DNQ11_23705 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DNQ11_23710 ENOG4105DFF Rod shape-determining protein mreb DNQ11_23735 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DNQ11_23740 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DNQ11_23750 ENOG41068KH stage VI sporulation protein D DNQ11_23760 ENOG4105D52 delta-aminolevulinic acid dehydratase DNQ11_23785 ENOG4105K56 Transcriptional regulator DNQ11_23805 ENOG4108IUQ atp-dependent protease DNQ11_23835 ENOG4108QCI YvbH-like oligomerisation region DNQ11_23860 ENOG4105M59 Phosphodiesterase, mj0936 family DNQ11_23875 ENOG4108XJQ germination protein DNQ11_23895 ENOG4105KBX Transcriptional regulator, TetR family DNQ11_23910 ENOG4105PFC Transcriptional regulator DNQ11_23925 ENOG4105DZC cytosine deaminase DNQ11_23930 ENOG4105DZC cytosine deaminase DNQ11_23935 ENOG4105DEF Extracellular solute-binding protein, family 5 DNQ11_23940 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DNQ11_23955 ENOG4108JQ7 (ABC) transporter DNQ11_23965 ENOG4105DY9 regulatoR DNQ11_23980 ENOG41067S9 phage shock protein C, PspC DNQ11_23985 ENOG4108JCI Transcriptional regulator DNQ11_23995 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) DNQ11_24000 ENOG4108Z40 Transcriptional regulator DNQ11_24005 ENOG4105RHA ABC transporter, permease DNQ11_24010 ENOG4108IUX (ABC) transporter DNQ11_24015 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family DNQ11_24025 ENOG4105E14 MotA TolQ exbB proton channel DNQ11_24030 ENOG4108VXD carboxy-peptidase DNQ11_24040 ENOG4105E33 succinate dehydrogenase DNQ11_24050 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit DNQ11_24065 ENOG4105K63 Thioredoxin DNQ11_24070 ENOG4105C10 Electron transfer flavoprotein DNQ11_24075 ENOG4105BZJ Electron transfer flavoprotein DNQ11_24080 ENOG41060WC Enoyl-CoA hydratase DNQ11_24085 ENOG4107Z3H Transcriptional regulator, TetR family DNQ11_24090 ENOG4105CEY Amp-dependent synthetase and ligase DNQ11_24105 ENOG4105J76 Periplasmic binding protein DNQ11_24110 ENOG4105S6R Iron-hydroxamate transporter permease subunit DNQ11_24155 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_24170 ENOG4105DR4 Methyltransferase DNQ11_24185 ENOG4105KFN sortase, SrtB family DNQ11_24190 ENOG4105E0A ABC, transporter DNQ11_24205 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) DNQ11_24215 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) DNQ11_24225 ENOG4105FE9 pseudouridine synthase DNQ11_24240 ENOG4105DCG PHP domain protein DNQ11_24275 ENOG4105C5S asparaginyl-tRNA synthetase DNQ11_24280 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DNQ11_24290 ENOG4108RWN rrna methyltransferase DNQ11_24325 ENOG4105C0R drug resistance transporter emrb qaca subfamily DNQ11_24330 ENOG4105CW7 secretion protein, HlyD family DNQ11_24335 ENOG4108JGH Tetr family transcriptional regulator DNQ11_24340 ENOG4105CN9 Peptidase m42 family protein DNQ11_24360 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DNQ11_24365 ENOG4105C22 threonyL-tRNA synthetase DNQ11_24370 ENOG4108TDW sporulation protein YtxC DNQ11_24390 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DNQ11_24400 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DNQ11_24405 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DNQ11_24415 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DNQ11_24420 ENOG4105C2M dna polymerase I DNQ11_24425 ENOG4105BZU Histidine kinase DNQ11_24430 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_24455 ENOG4108HMX isocitrate dehydrogenase (NADP) DNQ11_24460 ENOG4105BZN citrate synthase DNQ11_24475 ENOG4108REF Sporulation integral membrane protein ytvi DNQ11_24480 ENOG4105FS0 cytoplasmic membrane protein DNQ11_24505 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DNQ11_24510 ENOG4105C6K Malic enzyme DNQ11_24515 ENOG4105C0B DNA polymerase III (alpha subunit) DNQ11_24520 ENOG4105VV2 DNQ11_24530 ENOG4105SFS phosphoesterase RecJ domain protein DNQ11_24570 ENOG4105DC7 peptidase M24 DNQ11_24610 ENOG4105Z7P Acetyltransferase (GNAT) family DNQ11_24615 ENOG41082W1 Cupin 2, conserved barrel domain protein DNQ11_24625 ENOG4105VZ8 Transcriptional regulator DNQ11_24645 ENOG4107YZX Universal stress protein DNQ11_24695 ENOG4108JYZ YitT family DNQ11_24715 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DNQ11_24725 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) DNQ11_24730 ENOG4105KBJ sporulation protein ytfj DNQ11_24745 ENOG4105EFZ amidohydrolase DNQ11_24755 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DNQ11_24780 ENOG4106KR7 LysR family Transcriptional regulator DNQ11_24800 ENOG4105C28 cystathionine DNQ11_24825 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DNQ11_24835 ENOG4105EMN RNA polymerase sigma factor DNQ11_24855 ENOG4105F1V Acetoin utilization protein DNQ11_24860 ENOG4105W87 Cbs domain DNQ11_24865 ENOG4105DGU Histone deacetylase DNQ11_24875 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DNQ11_24885 ENOG4107SNB ankyrin repeat protein YahD DNQ11_24890 ENOG4105EP9 oxidoreductase DNQ11_24920 ENOG4105ETE Transcriptional regulator (LacI family DNQ11_24945 ENOG4105C88 aminopeptidase DNQ11_24990 ENOG4108VDD TRNA binding domain protein DNQ11_25020 ENOG4105C8F Beta-lactamase domain protein DNQ11_25035 ENOG4108V15 phosphotransferase enzyme family DNQ11_25040 ENOG4108IUM Glycogen debranching enzyme DNQ11_25060 ENOG4105YW5 deoR family transcriptional regulator DNQ11_25075 ENOG4105CBX hi0933 family DNQ11_25115 ENOG4108VJ1 Transcriptional regulator (CarD family DNQ11_25120 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DNQ11_25125 ENOG4105CSC Glucose uptake protein DNQ11_25140 ENOG4108ZAF Molybdopterin DNQ11_25145 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein DNQ11_25150 ENOG4105CVM Molybdenum cofactor synthesis domain protein DNQ11_25160 ENOG4105D06 uba thif-type nad fad binding protein DNQ11_25185 ENOG41085GJ domain protein DNQ11_25195 ENOG4105DWV Homoserine O-trans-acetylase DNQ11_25205 ENOG4108B31 Spore germination protein DNQ11_25240 ENOG410605W Major Facilitator DNQ11_25245 ENOG4107S91 Sodium hydrogen exchanger DNQ11_25250 ENOG4105NCW Trka-c domain protein DNQ11_25265 ENOG4105C19 ABC transporter DNQ11_25285 ENOG4105N5T Radical SAM Protein DNQ11_25300 ENOG4105DA5 (ABC) transporter DNQ11_25335 ENOG4105E8V Alpha Beta Hydrolase Fold protein DNQ11_25340 ENOG4108Z0R Transferase DNQ11_25345 ENOG4105YVM Phosphoesterase, PA-phosphatase related DNQ11_25350 ENOG4105BZF Glycosyl transferase (Group 1 DNQ11_25360 ENOG4108RIR Molybdenum cofactor biosynthesis protein DNQ11_25420 ENOG4105EGD dinuclear metal center protein, YbgI family DNQ11_25425 ENOG4105BZU Histidine kinase DNQ11_25430 ENOG4105BZU Histidine kinase DNQ11_25435 ENOG4107S9D Alpha beta hydrolase DNQ11_25440 ENOG4107T7U Sulfatase DNQ11_25460 ENOG4105D2X ABC transporter substrate-binding protein DNQ11_25470 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component DNQ11_25530 ENOG4108V2W Carbonate dehydratase DNQ11_25535 ENOG4105C4M (Ubiquinol oxidase) subunit I DNQ11_25540 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DNQ11_25590 ENOG41087YS Phage shock protein A DNQ11_25625 ENOG4105BZU Histidine kinase DNQ11_25630 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_25655 ENOG4108UGV hypoxanthine phosphoribosyltransferase DNQ11_25660 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) DNQ11_25700 ENOG4107ZTW SNARE associated Golgi DNQ11_25715 ENOG4105C19 ABC transporter DNQ11_25720 ENOG41086D8 Transcriptional regulator DNQ11_25760 ENOG4105C6Z Gluconate DNQ11_25765 ENOG4105FDP GntR family transcriptional regulator DNQ11_25785 ENOG41069H0 dihydroorotase EC 3.5.2.3 DNQ11_25815 ENOG4105DTQ mandelate racemase muconate lactonizing DNQ11_25825 ENOG4108IPT Naphthoate synthase DNQ11_25830 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) DNQ11_25835 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) DNQ11_25840 ENOG4105E4F Isochorismate synthase DNQ11_25845 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DNQ11_25855 ENOG4105VEQ Cold shock protein DNQ11_25880 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) DNQ11_25890 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) DNQ11_25915 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DNQ11_26015 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DNQ11_26055 ENOG4105KT7 mgtC SapB transporter DNQ11_26060 ENOG4107PBV potassium channel DNQ11_26070 ENOG4107QYV phosphohexose isomerase DNQ11_26080 ENOG4105WG9 Conserved Protein DNQ11_26090 ENOG4105CHM Aminotransferase DNQ11_26095 ENOG4108ZB6 transcriptional regulator AsnC family DNQ11_26100 ENOG4105C5I Dehydrogenase DNQ11_26105 ENOG4108MUZ hydrolase DNQ11_26115 ENOG4105C87 Aminotransferase class I and II DNQ11_26125 ENOG4105Y38 Kinase-associated protein B DNQ11_26135 ENOG4107R3E Citrate transporter DNQ11_26155 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) DNQ11_26160 ENOG4105KA0 thioesterase Superfamily protein DNQ11_26180 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DNQ11_26200 ENOG41069ER domain protein DNQ11_26215 ENOG4105CEP NADH dehydrogenase DNQ11_26245 ENOG4105EWC Purine nucleoside phosphorylase DNQ11_26265 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DNQ11_26290 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DNQ11_26295 ENOG4105C4B ABC transporter, permease DNQ11_26300 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DNQ11_26345 ENOG41083MR nifu domain-containing protein DNQ11_26365 ENOG4108W5N phosphatidylglycerophosphatase a DNQ11_26375 ENOG4105DYS nad(p)h dehydrogenase (quinone) DNQ11_26380 ENOG4105D4U had-superfamily hydrolase, subfamily iia DNQ11_26395 ENOG4105CBT Fructose-1,6-bisphosphatase DNQ11_26415 ENOG4105MMD transcriptional regulator DNQ11_26420 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DNQ11_26425 ENOG4107TXC Transcriptional regulator DNQ11_26430 ENOG41090T1 Membrane DNQ11_26455 ENOG4105FAA peptidase M23 DNQ11_26465 ENOG4105KZD Domain of unknown function (DUF1805) DNQ11_26470 ENOG4107R8B 5'-nucleotidase DNQ11_26500 ENOG4105DIW FeS assembly protein SUFB DNQ11_26505 ENOG4108UNV SUF system FeS assembly protein, NifU family DNQ11_26510 ENOG4105C9B Cysteine desulfurase DNQ11_26515 ENOG4105JRK feS assembly protein SufD DNQ11_26520 ENOG4105C3K feS assembly ATPase SufC DNQ11_26525 ENOG4105D01 (LipO)protein DNQ11_26530 ENOG4105D01 (LipO)protein DNQ11_26535 ENOG4108UMI ABC transporter, permease DNQ11_26575 ENOG41080E8 Transcriptional regulator, Spx MgsR family DNQ11_26630 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DNQ11_26660 ENOG4108W8B Beta-lactamase domain protein DNQ11_26665 ENOG4105C1G acyl-Coa dehydrogenase DNQ11_26675 ENOG4105CHU acetyl-coa acetyltransferase DNQ11_26695 ENOG4105DZ1 carboxypeptidase DNQ11_26715 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer DNQ11_26735 ENOG4108SUT Major Facilitator Superfamily DNQ11_26740 ENOG4107R7I amino acid DNQ11_26750 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DNQ11_26760 ENOG4107AYK membrAne DNQ11_26800 ENOG4107ZTW SNARE associated Golgi DNQ11_26810 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein DNQ11_26815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_26820 ENOG4105BZU Histidine kinase DNQ11_26830 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DNQ11_26845 ENOG4105VG1 fes assembly suf system protein DNQ11_26850 ENOG4105D4Y metalloprotease DNQ11_26870 ENOG4107S91 Sodium hydrogen exchanger DNQ11_26875 ENOG4105NCW Trka-c domain protein DNQ11_26890 ENOG4108RMU ferritin dps family protein DNQ11_26905 ENOG4108URH decarboxylase DNQ11_26925 ENOG4105D9N nucleoside DNQ11_26930 ENOG4105D9N nucleoside DNQ11_26945 ENOG4108RYK Nad-dependent epimerase dehydratase DNQ11_26975 ENOG4105CV8 reductase DNQ11_26980 ENOG4105F27 Major Facilitator DNQ11_26985 ENOG4105KVH Transcriptional regulator DNQ11_27000 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DNQ11_27005 ENOG4105D4A Cell wall formation (By similarity) DNQ11_27015 ENOG4105C8Q Methyl-accepting chemotaxis DNQ11_27025 ENOG4105WMR Protein CrcB homolog DNQ11_27030 ENOG4105WMR Protein CrcB homolog DNQ11_27045 ENOG4108MK9 spermidine N(1)-acetyltransferase DNQ11_27050 ENOG4108VY7 phosphate-starvation-inducible protein PsiE DNQ11_27070 ENOG4108IPW abc transporter atp-binding protein DNQ11_27075 ENOG4105CM4 permease protein DNQ11_27110 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DNQ11_27120 ENOG4105XZU Preprotein translocase, subunit SecG DNQ11_27125 ENOG41067MG lrgb family DNQ11_27235 ENOG4105EFC phage portal protein HK97 family DNQ11_27260 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DNQ11_27270 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DNQ11_27275 ENOG4105CP7 Triose-phosphate isomerase DNQ11_27300 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_27320 ENOG41090VF Stage v sporulation protein ac DNQ11_27325 ENOG4105CZ3 stage V sporulation protein ad DNQ11_27340 ENOG4105H67 Protein of unknown function (DUF421) DNQ11_27345 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DNQ11_27355 ENOG4105KRI phosphocarrier protein (HPr DNQ11_27365 ENOG4105CHW UPF0052 protein DNQ11_27375 ENOG4108Z4K mutator MutT protein DNQ11_27385 ENOG4105C3M thioredoxin reductase DNQ11_27395 ENOG4108S4C acetyltransferase DNQ11_27415 ENOG41086DT Membrane protein of unknown function DNQ11_27425 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DNQ11_27430 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DNQ11_27435 ENOG4105D7V transposase DNQ11_27450 ENOG4107TXC Transcriptional regulator DNQ11_27485 ENOG4105DUM transcriptional regulator, lysR family DNQ11_27495 ENOG4108WS4 fmn reductase DNQ11_27510 ENOG4105BZ1 (ABC) transporter DNQ11_27520 ENOG4105CN1 protease DNQ11_27525 ENOG4105CRP Part of the ABC transporter FtsEX involved in DNQ11_27530 ENOG4105CAK Cell division ATP-binding protein ftsE DNQ11_27550 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DNQ11_27555 ENOG4105MS2 ribosomal subunit Interface protein DNQ11_27560 ENOG4105VEQ Cold shock protein DNQ11_27565 ENOG41081UC Inherit from COG: Competence protein DNQ11_27580 ENOG4105KVH Transcriptional regulator DNQ11_27595 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DNQ11_27600 ENOG4108KGH TRANSCRIPTIONal DNQ11_27605 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DNQ11_27610 ENOG4105C6Y Udp-glucose 6-dehydrogenase DNQ11_27615 ENOG4105ESV Glycosyl transferase, family 4 DNQ11_27625 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DNQ11_27640 ENOG410901P UPF0249 protein DNQ11_27645 ENOG4105F8D glycoside hydrolase family 4 DNQ11_27650 ENOG4105VCP PTS System DNQ11_27655 ENOG4105CK1 PTS System DNQ11_27665 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) DNQ11_27670 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DNQ11_27675 ENOG4105VCP PTS System DNQ11_27685 ENOG4105VZJ PTS System DNQ11_27700 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase DNQ11_27705 ENOG4105ECB domain protein DNQ11_27710 ENOG4107RSM transcriptional regulator DNQ11_27755 ENOG4105DAA L-lactate DNQ11_27765 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) DNQ11_27780 ENOG4105E0M Sulfatase DNQ11_27810 ENOG4107R8N Glycosyl transferase, family 2 DNQ11_27820 ENOG4105C94 Transporter DNQ11_27830 ENOG41069ER domain protein DNQ11_27855 ENOG4105KBK Zinc finger, swim domain protein DNQ11_27860 ENOG4105C0D helicase DNQ11_27890 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DNQ11_27900 ENOG4107RBB ABC transporter, permease DNQ11_27905 ENOG4105C19 ABC transporter DNQ11_27925 ENOG4105CXY transporter DNQ11_27940 ENOG4105BZU Histidine kinase DNQ11_27945 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_27950 ENOG4105CMR udp-glucose 4-epimerase DNQ11_27970 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DNQ11_27975 ENOG4105EY8 ABC transporter DNQ11_28030 ENOG4105MT0 Sporulation transcriptional regulator spoiiid DNQ11_28045 ENOG4105FRN stage II sporulation protein DNQ11_28080 ENOG4106778 Protein of unknown function (DUF1146) DNQ11_28090 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DNQ11_28095 ENOG4105C8S subunit m DNQ11_28100 ENOG4105D65 subunit l DNQ11_28125 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DNQ11_28130 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DNQ11_28140 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DNQ11_28145 ENOG4105BZU Histidine kinase DNQ11_28195 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) DNQ11_28200 ENOG41062M3 atp synthase DNQ11_28230 ENOG4108YZG isomerase DNQ11_28250 ENOG4108VGI doxx family DNQ11_28255 ENOG4107XC4 flavin reductase domain protein, FMN-binding DNQ11_28275 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DNQ11_28285 ENOG4108ZXQ stage ii sporulation protein r DNQ11_28290 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DNQ11_28295 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) DNQ11_28310 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DNQ11_28315 ENOG4105CBT Fructose-1,6-bisphosphatase DNQ11_28325 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DNQ11_28360 ENOG4105C1G acyl-Coa dehydrogenase DNQ11_28365 ENOG4105C1G acyl-Coa dehydrogenase DNQ11_28370 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DNQ11_28380 ENOG4105DF6 Fe-S oxidoreductase DNQ11_28395 ENOG4105BZU Histidine kinase DNQ11_28420 ENOG4105BZU Histidine kinase DNQ11_28425 ENOG4105KCT ABC transporter DNQ11_28430 ENOG4108M15 ABC transporter DNQ11_28435 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) DNQ11_28455 ENOG4105IIU Aminopeptidase DNQ11_28475 ENOG4105EMN RNA polymerase sigma factor DNQ11_28485 ENOG410684U Domain of unknown function (DUF1934) DNQ11_28510 ENOG4105CYW agmatinase DNQ11_28520 ENOG4105DXB Major Facilitator superfamily DNQ11_28525 ENOG4107SWG transcriptional regulator MERR family DNQ11_28530 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DNQ11_28535 ENOG4105BZ4 penicillin-binding protein DNQ11_28545 ENOG4108XFG YwhD family DNQ11_28550 ENOG4108Z4T Peptidase M50 DNQ11_28555 ENOG41069HH 4-oxalocrotonate tautomerase DNQ11_28560 ENOG4105DCI Phosphohydrolase DNQ11_28565 ENOG4108MES Periplasmic binding protein DNQ11_28575 ENOG4105EHG Permease protein DNQ11_28590 ENOG4108VCI transcription factor, rsfa family DNQ11_28605 ENOG4108IJ2 phosphate acetyltransferase DNQ11_28620 ENOG4108VKI Cell wall hydrolase DNQ11_28640 ENOG4107SVH Potassium channel protein DNQ11_28650 ENOG410667J hydrolase DNQ11_28655 ENOG4105VCH membrane DNQ11_28665 ENOG4108TU7 Inherit from COG: (ABC) transporter DNQ11_28670 ENOG4105CJ1 ABC, transporter DNQ11_28675 ENOG41090WU lipolytic protein G-D-S-L family DNQ11_28715 ENOG4108Y4K DNA-binding transcriptional activator DNQ11_28725 ENOG4105WH1 Two component transcriptional regulator luxr family DNQ11_28735 ENOG4105DWF phosphomethylpyrimidine kinase DNQ11_28740 ENOG4105BZU Histidine kinase DNQ11_28745 ENOG4105VCD cytoplasmic protein DNQ11_28750 ENOG4105D22 carbon starvation protein DNQ11_28755 ENOG4105DY9 regulatoR DNQ11_28760 ENOG41079KZ Major Facilitator Superfamily DNQ11_28780 ENOG4105EN6 Membrane DNQ11_28785 ENOG4106YBV Methyl-accepting chemotaxis DNQ11_28795 ENOG4108S4H thioesterase Superfamily protein DNQ11_28805 ENOG4105JEU Glycosyl transferase, family 2 DNQ11_28810 ENOG4105C5H ABC transporter DNQ11_28840 ENOG4105CKK Glycosyl transferase, family 2 DNQ11_28845 ENOG41067SE Tetr family transcriptional regulator DNQ11_28855 ENOG4105E0X reductase DNQ11_28860 ENOG4106F5Q Membrane DNQ11_28875 ENOG4105DY9 regulatoR DNQ11_28880 ENOG4108HRK Histidine kinase DNQ11_28885 ENOG4107RGD Major Facilitator superfamily DNQ11_28905 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DNQ11_28915 ENOG4105IW1 AmiS UreI transporter DNQ11_28925 ENOG4105CMR udp-glucose 4-epimerase DNQ11_28930 ENOG4108UT2 hemolysin iii DNQ11_28940 ENOG4105C1J atp-dependent rna helicase DNQ11_28955 ENOG4105DPN Oligoendopeptidase f DNQ11_28975 ENOG4105C0H protease DNQ11_28980 ENOG4105Q2H domain protein DNQ11_28995 ENOG4105BZU Histidine kinase DNQ11_29000 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DNQ11_29030 ENOG4105CDU Replicative dna helicase DNQ11_29040 ENOG4105BZR domain protein DNQ11_29045 ENOG4108XMW Membrane DNQ11_29055 ENOG4108UUM single-stranded DNA-binding protein DNQ11_29065 ENOG4105C3G gtp-binding protein DNQ11_29070 ENOG4105VDK protein, conserved in bacteria DNQ11_29075 ENOG4105D8X mechanosensitive ion channel DNQ11_29080 ENOG4108ZDA Sporulation protein YyaC DNQ11_29085 ENOG4105FA0 parb-like partition protein DNQ11_29090 ENOG4107QJE Chromosome Partitioning Protein DNQ11_29110 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) DNQ11_29120 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DNQ11_29185 ENOG4105EKQ RNA-directed DNA polymerase DNQ11_29280 ENOG4105EKQ RNA-directed DNA polymerase DNQ11_29345 ENOG4106JUT Streptomycin 3''-adenylyltransferase DNQ11_29400 ENOG4105CNU cell division protein FtsK DNQ11_29625 ENOG4105DHF Membrane DNQ11_29645 ENOG4106AKK s-layer domain-containing protein DNQ11_29650 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DNQ11_29680 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DNQ11_29685 ENOG4105C6Y Udp-glucose 6-dehydrogenase DNQ11_29735 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) DNQ11_29750 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DNQ11_29875 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DNQ11_29905 ENOG4108IBT Inherit from COG: transposase DNQ11_29930 ENOG4108MEK Metal-binding protein YodA DNQ11_29945 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) DNQ11_29975 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DNQ11_30050 ENOG4105K4H Nlp p60 protein DNQ11_30215 ENOG4107QJE Chromosome Partitioning Protein DNQ11_30270 ENOG4105EWC Purine nucleoside phosphorylase DNQ11_30360 ENOG4105C3F Signal peptidase i DNQ11_30385 ENOG4105N14 lysine exporter protein LysE YggA DNQ11_30425 ENOG4108J59 Extracellular solute-binding protein, family 5 DNQ11_30440 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)