locus-tag	class	description
DY471_00010	COG0592	DNA-directed DNA polymerase activity
DY471_00015	COG2501	S4 domain
DY471_00025	COG0187	DNA topoisomerase II activity
DY471_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DY471_00065	COG0517	IMP dehydrogenase activity
DY471_00065	COG0516	GMP reductase activity
DY471_00070	COG1686	Belongs to the peptidase S11 family
DY471_00100	COG1428	Deoxynucleoside kinase
DY471_00105	COG1428	Deoxynucleoside kinase
DY471_00110	COG1335	isochorismatase
DY471_00115	COG0590	tRNA wobble adenosine to inosine editing
DY471_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DY471_00180	COG1982	Orn Lys Arg decarboxylase major
DY471_00190	COG0470	DNA polymerase III
DY471_00195	COG1774	PSP1 C-terminal conserved region
DY471_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DY471_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DY471_00220	COG2002	toxin-antitoxin pair type II binding
DY471_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DY471_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DY471_00230	COG0084	hydrolase, TatD family'
DY471_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DY471_00250	COG4466	Protein conserved in bacteria
DY471_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DY471_00270	COG0251	oxidation-reduction process
DY471_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DY471_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DY471_00305	COG2002	toxin-antitoxin pair type II binding
DY471_00310	COG2244	polysaccharide biosynthetic process
DY471_00315	COG3956	TIGRFAM MazG family protein
DY471_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DY471_00340	COG1098	S1 RNA binding domain
DY471_00355	COG2208	phosphoserine phosphatase activity
DY471_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DY471_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DY471_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DY471_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
DY471_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DY471_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DY471_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DY471_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DY471_00420	COG1396	sequence-specific DNA binding
DY471_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DY471_00515	COG3880	PFAM UvrB UvrC protein
DY471_00525	COG0542	response to heat
DY471_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DY471_00540	COG4956	integral membrane protein (PIN domain superfamily)
DY471_00560	COG1045	serine acetyltransferase
DY471_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DY471_00580	COG3688	RNA-binding protein containing a PIN domain
DY471_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DY471_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DY471_00600	COG0250	Participates in transcription elongation, termination and antitermination
DY471_00625	COG2813	Specifically methylates the guanine in position
DY471_00640	COG1358	cellular component organization or biogenesis
DY471_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DY471_00770	COG0201	protein transport
DY471_00780	COG0024	Methionine aminopeptidase
DY471_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DY471_00820	COG1122	ATPase activity
DY471_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DY471_00830	COG0101	tRNA pseudouridine synthase activity
DY471_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
DY471_00855	COG0489	protein tyrosine kinase activity
DY471_00865	COG2194	sulfuric ester hydrolase activity
DY471_00870	COG0726	polysaccharide deacetylase
DY471_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DY471_00955	COG4856	YbbR-like protein
DY471_01000	COG0596	Alpha beta hydrolase
DY471_01020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DY471_01025	COG4946	Tricorn protease homolog
DY471_01025	COG1506	peptidase
DY471_01025	COG0823	Involved in the tonB-independent uptake of proteins
DY471_01055	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_01060	COG2011	ABC-type metal ion transport system permease component
DY471_01070	COG1464	Belongs to the NlpA lipoprotein family
DY471_01085	COG0277	FAD linked oxidase domain protein
DY471_01090	COG2271	Major facilitator Superfamily
DY471_01100	COG2814	Major facilitator Superfamily
DY471_01115	COG0601	transmembrane transport
DY471_01120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DY471_01125	COG0444	Belongs to the ABC transporter superfamily
DY471_01130	COG4608	Belongs to the ABC transporter superfamily
DY471_01135	COG4166	transmembrane transport
DY471_01145	COG2207	Transcriptional regulator
DY471_01155	COG1309	transcriptional regulator
DY471_01165	COG4166	transmembrane transport
DY471_01170	COG4166	transmembrane transport
DY471_01175	COG0656	L-ascorbic acid biosynthetic process
DY471_01180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DY471_01195	COG4149	molybdate abc transporter
DY471_01200	COG0725	ABC transporter, periplasmic molybdate-binding protein
DY471_01205	COG1910	domain protein
DY471_01220	COG0697	spore germination
DY471_01235	COG0204	Acyl-transferase
DY471_01245	COG1609	Transcriptional regulator
DY471_01255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_01275	COG5298	Protein conserved in bacteria
DY471_01295	COG0488	(ABC) transporter
DY471_01300	COG4585	Histidine kinase
DY471_01305	COG2197	response regulator
DY471_01310	COG1131	(ABC) transporter
DY471_01315	COG0842	Transport permease protein
DY471_01315	COG1511	domain protein
DY471_01320	COG0842	Transport permease protein
DY471_01330	COG0747	negative chemotaxis
DY471_01335	COG0601	transmembrane transport
DY471_01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DY471_01345	COG0444	Belongs to the ABC transporter superfamily
DY471_01350	COG4608	Belongs to the ABC transporter superfamily
DY471_01355	COG0561	phosphatase activity
DY471_01385	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DY471_01390	COG0179	Fumarylacetoacetate (FAA) hydrolase
DY471_01400	COG0531	amino acid
DY471_01415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DY471_01425	COG4294	response to UV
DY471_01430	COG0705	Rhomboid family
DY471_01440	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DY471_01445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DY471_01450	COG0864	Transcriptional regulator
DY471_01455	COG2337	Toxic component of a toxin-antitoxin (TA) module
DY471_01460	COG2183	response to ionizing radiation
DY471_01555	COG0802	atpase or kinase
DY471_01560	COG1214	PFAM Peptidase M22, glycoprotease
DY471_01565	COG0456	acetyltransferase
DY471_01570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DY471_01575	COG0488	(ABC) transporter
DY471_01590	COG1266	CAAX protease self-immunity
DY471_01635	COG2946	Replication initiation factor
DY471_01650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DY471_01660	COG2252	PERMEase
DY471_01670	COG5002	protein histidine kinase activity
DY471_01695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DY471_01770	COG2205	protein histidine kinase activity
DY471_01775	COG0745	RESPONSE REGULATOR receiver
DY471_01795	COG0697	spore germination
DY471_01825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DY471_01830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DY471_01835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DY471_01845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DY471_01860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DY471_01870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DY471_01880	COG0151	Belongs to the GarS family
DY471_01910	COG0210	DNA helicase
DY471_01920	COG4851	CamS sex pheromone cAM373 precursor
DY471_01935	COG1335	isochorismatase
DY471_01950	COG2011	ABC-type metal ion transport system permease component
DY471_01955	COG1464	Belongs to the NlpA lipoprotein family
DY471_01970	COG0003	Pfam Anion-transporting ATPase
DY471_01975	COG1846	Transcriptional regulator
DY471_01980	COG4682	membrane
DY471_02000	COG1597	lipid kinase activity
DY471_02005	COG0546	phosphoglycolate phosphatase activity
DY471_02010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DY471_02020	COG1012	belongs to the aldehyde dehydrogenase family
DY471_02025	COG2076	Multidrug Resistance protein
DY471_02030	COG2309	aminopeptidase activity
DY471_02045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_02050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DY471_02055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DY471_02065	COG5002	protein histidine kinase activity
DY471_02070	COG4807	Protein conserved in bacteria
DY471_02100	COG1473	amidohydrolase
DY471_02115	COG0450	alkyl hydroperoxide reductase
DY471_02120	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DY471_02130	COG0235	Class ii aldolase
DY471_02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_02145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_02170	COG0166	Belongs to the GPI family
DY471_02200	COG5002	protein histidine kinase activity
DY471_02220	COG3541	Predicted nucleotidyltransferase
DY471_02225	COG2814	Major facilitator Superfamily
DY471_02230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DY471_02230	COG0723	plastoquinol--plastocyanin reductase activity
DY471_02240	COG0765	amino acid transport
DY471_02245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DY471_02255	COG0840	transmembrane signaling receptor activity
DY471_02260	COG0366	Alpha amylase catalytic
DY471_02265	COG1263	PTS System
DY471_02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_02265	COG2190	(PTS) system
DY471_02300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DY471_02315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DY471_02325	COG1116	anion transmembrane transporter activity
DY471_02330	COG0488	(ABC) transporter
DY471_02380	COG2270	Major facilitator Superfamily
DY471_02405	COG4193	domain, Protein
DY471_02415	COG2310	stress, protein
DY471_02420	COG2310	stress, protein
DY471_02425	COG2310	stress, protein
DY471_02430	COG0861	Integral membrane protein TerC family
DY471_02440	COG3853	Toxic anion resistance protein (TelA)
DY471_02455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DY471_02465	COG1295	ribonuclease BN
DY471_02470	COG2217	Heavy metal translocating P-type atpase
DY471_02475	COG0697	spore germination
DY471_02495	COG0681	Belongs to the peptidase S26 family
DY471_02505	COG0586	Pfam SNARE associated Golgi protein
DY471_02520	COG3871	stress protein (general stress protein 26)
DY471_02525	COG0387	Pfam Sodium calcium exchanger
DY471_02535	COG0535	radical SAM domain protein
DY471_02555	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DY471_02565	COG0101	tRNA pseudouridine synthase activity
DY471_02575	COG3829	transcription factor binding
DY471_02585	COG0833	amino acid
DY471_02590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DY471_02610	COG2066	Belongs to the glutaminase family
DY471_02620	COG1263	PTS System
DY471_02620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_02625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DY471_02645	COG0463	Glycosyl transferase, family 2
DY471_02670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DY471_02690	COG1228	amidohydrolase
DY471_02695	COG1090	epimerase
DY471_02725	COG1988	membrane-bound metal-dependent
DY471_02730	COG1194	a g-specific adenine glycosylase
DY471_02755	COG1132	(ABC) transporter
DY471_02760	COG4129	membrane
DY471_02765	COG0070	glutamate synthase
DY471_02765	COG0067	glutamate synthase
DY471_02765	COG0069	glutamate synthase activity
DY471_02775	COG4555	ABC transporter
DY471_02795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DY471_02800	COG0735	belongs to the Fur family
DY471_02915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DY471_02920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DY471_02930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DY471_02940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DY471_02950	COG2766	serine protein kinase
DY471_02970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DY471_02980	COG1585	Membrane protein implicated in regulation of membrane protease activity
DY471_02985	COG2268	Band 7 protein
DY471_02995	COG3290	protein histidine kinase activity
DY471_03000	COG4565	transcriptional regulatory protein
DY471_03005	COG2851	Citrate transporter
DY471_03030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DY471_03035	COG3842	ATPase activity
DY471_03040	COG1175	transmembrane transport
DY471_03045	COG0395	ABC-type sugar transport system, permease component
DY471_03055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DY471_03060	COG0745	RESPONSE REGULATOR receiver
DY471_03065	COG5002	protein histidine kinase activity
DY471_03075	COG4990	cell redox homeostasis
DY471_03085	COG3290	protein histidine kinase activity
DY471_03090	COG4565	transcriptional regulatory protein
DY471_03095	COG3493	citrate carrier protein
DY471_03100	COG0281	malic enzyme
DY471_03110	COG0697	spore germination
DY471_03115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_03125	COG5002	protein histidine kinase activity
DY471_03130	COG0745	RESPONSE REGULATOR receiver
DY471_03135	COG0456	acetyltransferase
DY471_03135	COG0454	-acetyltransferase
DY471_03140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DY471_03145	COG3383	formate dehydrogenase (NAD+) activity
DY471_03150	COG2427	Protein of unknown function (DUF1641)
DY471_03165	COG0531	amino acid
DY471_03170	COG0640	Transcriptional regulator
DY471_03175	COG2217	Heavy metal translocating P-type atpase
DY471_03180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DY471_03190	COG3227	Zinc metalloprotease (Elastase)
DY471_03210	COG2720	vancomycin resistance protein
DY471_03215	COG1316	TRANSCRIPTIONal
DY471_03220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_03225	COG0346	lactoylglutathione lyase activity
DY471_03230	COG1253	flavin adenine dinucleotide binding
DY471_03235	COG1027	Aspartate ammonia-lyase
DY471_03240	COG1620	l-lactate permease
DY471_03255	COG3104	oligopeptide transport
DY471_03260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_03280	COG2226	methyltransferase
DY471_03285	COG0156	8-amino-7-oxononanoate synthase activity
DY471_03290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DY471_03295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DY471_03305	COG4548	von Willebrand factor, type A
DY471_03310	COG0714	Associated with various cellular activities
DY471_03315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DY471_03335	COG0531	amino acid
DY471_03340	COG2188	Transcriptional regulator
DY471_03345	COG1263	PTS System
DY471_03345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_03350	COG0366	Alpha amylase catalytic
DY471_03365	COG0697	spore germination
DY471_03375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DY471_03380	COG1115	amino acid carrier protein
DY471_03385	COG1126	abc transporter atp-binding protein
DY471_03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DY471_03395	COG0765	amino acid transport
DY471_03400	COG0765	amino acid transport
DY471_03405	COG0833	amino acid
DY471_03430	COG2378	regulation of single-species biofilm formation
DY471_03435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DY471_03440	COG5002	protein histidine kinase activity
DY471_03455	COG0659	secondary active sulfate transmembrane transporter activity
DY471_03470	COG0747	negative chemotaxis
DY471_03480	COG0601	transmembrane transport
DY471_03485	COG4608	Belongs to the ABC transporter superfamily
DY471_03495	COG2271	Major facilitator Superfamily
DY471_03500	COG1846	Transcriptional regulator
DY471_03505	COG0477	Major facilitator Superfamily
DY471_03510	COG1609	Transcriptional regulator
DY471_03515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DY471_03525	COG1129	ABC transporter
DY471_03530	COG1172	Belongs to the binding-protein-dependent transport system permease family
DY471_03535	COG1879	ABC-type sugar transport system periplasmic component
DY471_03540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DY471_03550	COG0860	N-Acetylmuramoyl-L-alanine amidase
DY471_03560	COG1063	alcohol dehydrogenase
DY471_03575	COG3568	Endonuclease Exonuclease Phosphatase
DY471_03605	COG0840	transmembrane signaling receptor activity
DY471_03610	COG1388	LysM domain
DY471_03610	COG3584	3D domain protein
DY471_03615	COG1476	TRANSCRIPTIONal
DY471_03630	COG3104	oligopeptide transport
DY471_03635	COG1114	Component of the transport system for branched-chain amino acids
DY471_03650	COG1113	amino acid transport
DY471_03655	COG2252	PERMEase
DY471_03670	COG2153	protein acetylation
DY471_03680	COG0569	domain protein
DY471_03680	COG0475	glutathione-regulated potassium exporter activity
DY471_03695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DY471_03700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DY471_03705	COG0833	amino acid
DY471_03710	COG4990	cell redox homeostasis
DY471_03725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DY471_03730	COG0697	spore germination
DY471_03735	COG0531	amino acid
DY471_03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DY471_03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DY471_03755	COG1918	ferrous iron import across plasma membrane
DY471_03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DY471_03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DY471_03765	COG0573	inorganic phosphate transmembrane transporter activity
DY471_03770	COG0581	inorganic phosphate transmembrane transporter activity
DY471_03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DY471_03900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DY471_03920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DY471_03925	COG1116	anion transmembrane transporter activity
DY471_03930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DY471_03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DY471_03940	COG0352	thiamine-phosphate diphosphorylase activity
DY471_03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DY471_03950	COG2104	thiamine diphosphate biosynthetic process
DY471_03960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DY471_03965	COG0351	phosphomethylpyrimidine kinase
DY471_04005	COG2205	protein histidine kinase activity
DY471_04010	COG2814	Major facilitator Superfamily
DY471_04015	COG1846	Transcriptional regulator
DY471_04030	COG2252	PERMEase
DY471_04035	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_04055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DY471_04095	COG0778	Nitroreductase
DY471_04100	COG2719	SpoVR family
DY471_04105	COG1401	restriction endodeoxyribonuclease activity
DY471_04115	COG0446	pyridine nucleotide-disulphide oxidoreductase
DY471_04120	COG1937	Protein conserved in bacteria
DY471_04125	COG0425	Belongs to the sulfur carrier protein TusA family
DY471_04125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DY471_04130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DY471_04135	COG0425	Belongs to the sulfur carrier protein TusA family
DY471_04140	COG0425	Belongs to the sulfur carrier protein TusA family
DY471_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DY471_04160	COG2210	Belongs to the sulfur carrier protein TusA family
DY471_04165	COG0730	response to heat
DY471_04175	COG1316	TRANSCRIPTIONal
DY471_04180	COG0604	alcohol dehydrogenase
DY471_04185	COG1283	sodium-dependent phosphate transmembrane transporter activity
DY471_04190	COG2814	Major facilitator Superfamily
DY471_04205	COG3711	transcriptional antiterminator
DY471_04205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DY471_04210	COG1447	Phosphotransferase system cellobiose-specific component IIA
DY471_04215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DY471_04235	COG3584	3D domain protein
DY471_04235	COG1388	LysM domain
DY471_04240	COG0577	efflux transmembrane transporter activity
DY471_04245	COG1136	(ABC) transporter
DY471_04255	COG5522	Integral membrane protein (intg_mem_TP0381)
DY471_04270	COG1114	Component of the transport system for branched-chain amino acids
DY471_04275	COG3546	catalase activity
DY471_04310	COG0586	Pfam SNARE associated Golgi protein
DY471_04340	COG0531	amino acid
DY471_04345	COG0475	glutathione-regulated potassium exporter activity
DY471_04355	COG1737	Transcriptional regulator
DY471_04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_04365	COG1263	PTS System
DY471_04375	COG2259	Doxx family
DY471_04390	COG0697	spore germination
DY471_04395	COG1522	sequence-specific DNA binding
DY471_04405	COG0300	oxidoreductase activity
DY471_04415	COG2076	Multidrug Resistance protein
DY471_04420	COG2076	Multidrug Resistance protein
DY471_04425	COG1309	transcriptional regulator
DY471_04430	COG2814	Major facilitator Superfamily
DY471_04435	COG1733	regulation of RNA biosynthetic process
DY471_04445	COG2249	NAD(P)H dehydrogenase (quinone) activity
DY471_04455	COG4533	DNA binding
DY471_04460	COG2211	Major facilitator Superfamily
DY471_04470	COG0693	protein deglycase activity
DY471_04485	COG0531	amino acid
DY471_04490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DY471_04500	COG1012	belongs to the aldehyde dehydrogenase family
DY471_04515	COG1132	(ABC) transporter
DY471_04520	COG1132	(ABC) transporter
DY471_04530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DY471_04535	COG0765	amino acid transport
DY471_04540	COG1126	abc transporter atp-binding protein
DY471_04555	COG0189	ligase activity
DY471_04585	COG0028	Belongs to the TPP enzyme family
DY471_04590	COG3527	Alpha-acetolactate decarboxylase
DY471_04600	COG0561	phosphatase activity
DY471_04615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DY471_04635	COG0659	secondary active sulfate transmembrane transporter activity
DY471_04645	COG1024	Enoyl-CoA hydratase
DY471_04660	COG1363	Peptidase, m42
DY471_04680	COG3938	Belongs to the proline racemase family
DY471_04705	COG0601	transmembrane transport
DY471_04710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DY471_04715	COG0444	Belongs to the ABC transporter superfamily
DY471_04720	COG4608	Belongs to the ABC transporter superfamily
DY471_04730	COG0457	Tetratricopeptide repeat
DY471_04745	COG0582	viral genome integration into host DNA
DY471_04750	COG0477	Major facilitator Superfamily
DY471_04755	COG3290	protein histidine kinase activity
DY471_04760	COG4565	transcriptional regulatory protein
DY471_04765	COG3181	Tripartite tricarboxylate transporter family receptor
DY471_04805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DY471_04835	COG0305	Participates in initiation and elongation during chromosome replication
DY471_04860	COG0477	Major facilitator Superfamily
DY471_04910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DY471_04910	COG3320	Male sterility
DY471_04925	COG3711	transcriptional antiterminator
DY471_04930	COG2190	(PTS) system
DY471_04930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_04930	COG1263	PTS System
DY471_04935	COG2723	6-phospho-beta-galactosidase activity
DY471_04945	COG1183	phosphatidylcholine synthase activity
DY471_04985	COG2376	Dihydroxyacetone kinase
DY471_05000	COG2376	Dihydroxyacetone kinase
DY471_05105	COG1136	(ABC) transporter
DY471_05110	COG0577	efflux transmembrane transporter activity
DY471_05115	COG0596	Alpha beta hydrolase
DY471_05135	COG3237	CsbD-like
DY471_05160	COG1191	sigma factor activity
DY471_05170	COG2208	phosphoserine phosphatase activity
DY471_05175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DY471_05180	COG0784	Response regulator, receiver
DY471_05180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DY471_05180	COG2198	Histidine kinase
DY471_05180	COG2205	protein histidine kinase activity
DY471_05200	COG0393	Putative heavy-metal-binding
DY471_05215	COG0745	RESPONSE REGULATOR receiver
DY471_05220	COG2205	protein histidine kinase activity
DY471_05260	COG0420	3'-5' exonuclease activity
DY471_05265	COG4717	serine-type aminopeptidase activity
DY471_05305	COG0346	lactoylglutathione lyase activity
DY471_05310	COG0346	lactoylglutathione lyase activity
DY471_05315	COG0457	Tetratricopeptide repeat
DY471_05320	COG2267	carboxylic ester hydrolase activity
DY471_05345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DY471_05350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DY471_05360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DY471_05375	COG0772	Belongs to the SEDS family
DY471_05390	COG0477	Major facilitator Superfamily
DY471_05395	COG0477	Major facilitator Superfamily
DY471_05405	COG3973	AAA domain
DY471_05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DY471_05430	COG4980	gas vesicle protein
DY471_05435	COG0537	adenosine 5'-monophosphoramidase activity
DY471_05440	COG1131	(ABC) transporter
DY471_05445	COG4473	ABC transporter
DY471_05515	COG1309	transcriptional regulator
DY471_05520	COG3402	PFAM membrane-flanked domain
DY471_05525	COG3428	Bacterial PH domain
DY471_05545	COG3402	PFAM membrane-flanked domain
DY471_05550	COG3428	Bacterial PH domain
DY471_05555	COG2329	Antibiotic biosynthesis monooxygenase
DY471_05560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DY471_05610	COG1309	transcriptional regulator
DY471_05615	COG1511	domain protein
DY471_05630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_05640	COG2378	regulation of single-species biofilm formation
DY471_05650	COG1609	Transcriptional regulator
DY471_05660	COG1234	tRNA 3'-trailer cleavage
DY471_05665	COG0095	Lipoate-protein ligase
DY471_05675	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_05695	COG1408	metallophosphoesterase
DY471_05705	COG1078	dGTPase activity
DY471_05710	COG1733	regulation of RNA biosynthetic process
DY471_05715	COG0477	Major facilitator Superfamily
DY471_05725	COG1595	DNA-templated transcription, initiation
DY471_05735	COG3708	Transcriptional regulator
DY471_05735	COG2207	Transcriptional regulator
DY471_05745	COG2205	protein histidine kinase activity
DY471_05750	COG0745	RESPONSE REGULATOR receiver
DY471_05775	COG0501	Belongs to the peptidase M48B family
DY471_05780	COG0840	transmembrane signaling receptor activity
DY471_05785	COG0697	spore germination
DY471_05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DY471_05800	COG2224	Isocitrate lyase
DY471_05810	COG1278	Cold shock
DY471_05825	COG4903	ComK protein
DY471_05830	COG0398	Pfam SNARE associated Golgi protein
DY471_05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
DY471_05915	COG0367	asparagine synthase
DY471_05925	COG0753	catalase activity
DY471_05930	COG0004	ammonium transporteR
DY471_05955	COG2996	Protein conserved in bacteria
DY471_05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DY471_05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_05985	COG0561	phosphatase activity
DY471_05995	COG0542	response to heat
DY471_06005	COG2267	carboxylic ester hydrolase activity
DY471_06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DY471_06030	COG5504	Zn-dependent protease
DY471_06045	COG0180	Tryptophanyl-tRNA synthetase
DY471_06060	COG4166	transmembrane transport
DY471_06065	COG0601	transmembrane transport
DY471_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DY471_06075	COG0444	Belongs to the ABC transporter superfamily
DY471_06080	COG4608	Belongs to the ABC transporter superfamily
DY471_06085	COG0534	Mate efflux family protein
DY471_06090	COG4166	transmembrane transport
DY471_06100	COG1393	Belongs to the ArsC family
DY471_06105	COG0861	Integral membrane protein TerC family
DY471_06110	COG4862	establishment of competence for transformation
DY471_06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DY471_06125	COG1164	Oligoendopeptidase f
DY471_06135	COG2346	COG2346, Truncated hemoglobins
DY471_06140	COG4116	CYTH
DY471_06150	COG2357	RelA SpoT domain protein
DY471_06155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DY471_06160	COG0564	pseudouridine synthase activity
DY471_06175	COG0772	Belongs to the SEDS family
DY471_06180	COG1216	Glycosyl transferase, family 2
DY471_06180	COG0463	Glycosyl transferase, family 2
DY471_06200	COG0457	Tetratricopeptide repeat
DY471_06200	COG0463	Glycosyl transferase, family 2
DY471_06220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DY471_06235	COG1091	dTDP-4-dehydrorhamnose reductase activity
DY471_06280	COG2153	protein acetylation
DY471_06290	COG2382	esterase
DY471_06305	COG5492	domain, Protein
DY471_06310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DY471_06325	COG0512	Glutamine amidotransferase of anthranilate synthase
DY471_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DY471_06360	COG1620	l-lactate permease
DY471_06365	COG5634	Uncharacterized conserved protein (DUF2278)
DY471_06425	COG0508	dehydrogenase complex catalyzes the overall conversion of
DY471_06435	COG1476	TRANSCRIPTIONal
DY471_06500	COG2226	methyltransferase
DY471_06510	COG1686	Belongs to the peptidase S11 family
DY471_06515	COG0681	Belongs to the peptidase S26 family
DY471_06550	COG1012	belongs to the aldehyde dehydrogenase family
DY471_06560	COG1176	ABC-type spermidine putrescine transport system, permease component I
DY471_06565	COG1177	transmembrane transport
DY471_06570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DY471_06580	COG2409	Drug exporters of the RND superfamily
DY471_06590	COG0564	pseudouridine synthase activity
DY471_06600	COG2340	Cysteine-rich secretory protein family
DY471_06605	COG0247	lactate metabolic process
DY471_06610	COG0277	FAD linked oxidase domain protein
DY471_06615	COG3835	regulator
DY471_06625	COG0745	RESPONSE REGULATOR receiver
DY471_06630	COG5002	protein histidine kinase activity
DY471_06635	COG2186	Transcriptional regulator
DY471_06655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DY471_06665	COG2116	formate transmembrane transporter activity
DY471_06670	COG0861	Integral membrane protein TerC family
DY471_06675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DY471_06685	COG2030	dehydratase
DY471_06705	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_06710	COG3243	poly(R)-hydroxyalkanoic acid synthase
DY471_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DY471_06735	COG1840	ABC-type Fe3 transport system, periplasmic component
DY471_06740	COG3842	ATPase activity
DY471_06765	COG1349	DNA-binding transcription factor activity
DY471_06780	COG0235	Class ii aldolase
DY471_06790	COG2861	carbohydrate metabolic process
DY471_06800	COG3852	Histidine kinase
DY471_06805	COG1846	Transcriptional regulator
DY471_06815	COG2318	DinB family
DY471_06820	COG5002	protein histidine kinase activity
DY471_06830	COG0720	synthase
DY471_06845	COG4873	Protein conserved in bacteria
DY471_06875	COG1780	Probably involved in ribonucleotide reductase function
DY471_06900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DY471_06905	COG1725	Transcriptional regulator
DY471_06910	COG1131	(ABC) transporter
DY471_06920	COG1131	(ABC) transporter
DY471_06925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DY471_06930	COG1266	CAAX protease self-immunity
DY471_06940	COG1522	sequence-specific DNA binding
DY471_06950	COG1335	isochorismatase
DY471_06960	COG1619	proteins homologs of microcin C7 resistance protein MccF
DY471_06965	COG2070	2-Nitropropane dioxygenase
DY471_06970	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DY471_06980	COG1696	Membrane protein involved in D-alanine export
DY471_07000	COG0716	FMN binding
DY471_07010	COG3173	Aminoglycoside phosphotransferase
DY471_07030	COG1968	undecaprenyl-diphosphatase activity
DY471_07045	COG1846	Transcriptional regulator
DY471_07055	COG1301	dicarboxylic acid transport
DY471_07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DY471_07065	COG4709	membrane
DY471_07070	COG3874	Sporulation protein YtfJ
DY471_07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DY471_07100	COG0028	Belongs to the TPP enzyme family
DY471_07105	COG0440	acetolactate synthase activity
DY471_07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DY471_07195	COG1183	phosphatidylcholine synthase activity
DY471_07200	COG1368	sulfuric ester hydrolase activity
DY471_07210	COG0019	diaminopimelate decarboxylase activity
DY471_07230	COG0529	Catalyzes the synthesis of activated sulfate
DY471_07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DY471_07260	COG0733	neurotransmitter:sodium symporter activity
DY471_07280	COG1757	Na H antiporter
DY471_07295	COG4758	membrane
DY471_07300	COG4585	Histidine kinase
DY471_07305	COG2197	response regulator
DY471_07315	COG1114	Component of the transport system for branched-chain amino acids
DY471_07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DY471_07340	COG1994	Peptidase M50
DY471_07365	COG0730	response to heat
DY471_07370	COG0306	phosphate transporter
DY471_07375	COG1392	Phosphate transport regulator
DY471_07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DY471_07395	COG3852	Histidine kinase
DY471_07400	COG1801	Protein of unknown function DUF72
DY471_07410	COG0582	viral genome integration into host DNA
DY471_07415	COG5002	protein histidine kinase activity
DY471_07430	COG0392	lysyltransferase activity
DY471_07430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DY471_07445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DY471_07450	COG1686	Belongs to the peptidase S11 family
DY471_07455	COG2715	membrane protein required for spore maturation
DY471_07460	COG0700	Nucleoside recognition
DY471_07465	COG1187	pseudouridine synthase activity
DY471_07475	COG1333	cytochrome c biogenesis protein
DY471_07480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DY471_07485	COG0745	RESPONSE REGULATOR receiver
DY471_07490	COG5002	protein histidine kinase activity
DY471_07495	COG2096	Adenosyltransferase
DY471_07500	COG4942	peptidase
DY471_07510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DY471_07515	COG1141	Ferredoxin
DY471_07525	COG0514	ATP-dependent DNA helicase (RecQ)
DY471_07530	COG1266	CAAX protease self-immunity
DY471_07540	COG1408	metallophosphoesterase
DY471_07550	COG4862	establishment of competence for transformation
DY471_07555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DY471_07575	COG0492	ferredoxin-NADP+ reductase activity
DY471_07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DY471_07660	COG0142	geranyltranstransferase activity
DY471_07670	COG0142	geranyltranstransferase activity
DY471_07675	COG0105	UTP biosynthetic process
DY471_07695	COG0457	Tetratricopeptide repeat
DY471_07715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DY471_07725	COG4347	Protein of unknown function (DUF1405)
DY471_07740	COG2738	Putative neutral zinc metallopeptidase
DY471_07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_07760	COG1694	Mazg nucleotide pyrophosphohydrolase
DY471_07775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DY471_07780	COG0438	transferase activity, transferring glycosyl groups
DY471_07815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DY471_07815	COG1199	ATP-dependent helicase activity
DY471_07835	COG3935	DnaD domain protein
DY471_07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DY471_07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DY471_07850	COG4499	WXG100 protein secretion system (Wss), protein YukC
DY471_07905	COG0116	Belongs to the methyltransferase superfamily
DY471_07915	COG1199	ATP-dependent helicase activity
DY471_07920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DY471_07930	COG3173	Aminoglycoside phosphotransferase
DY471_07935	COG0024	Methionine aminopeptidase
DY471_07945	COG2233	PERMEase
DY471_07950	COG2311	Membrane
DY471_07955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DY471_07965	COG0456	acetyltransferase
DY471_08000	COG0754	glutathionylspermidine amidase activity
DY471_08015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DY471_08040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DY471_08055	COG1215	transferase activity, transferring glycosyl groups
DY471_08060	COG0438	transferase activity, transferring glycosyl groups
DY471_08095	COG0328	RNA-DNA hybrid ribonuclease activity
DY471_08130	COG3403	YqcI/YcgG family
DY471_08135	COG1280	lysine exporter protein (LysE YggA)
DY471_08150	COG3162	membrane
DY471_08155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DY471_08160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DY471_08170	COG0475	glutathione-regulated potassium exporter activity
DY471_08175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DY471_08180	COG0789	Transcriptional regulator
DY471_08180	COG4978	Transcriptional regulator
DY471_08190	COG2323	membrane
DY471_08195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DY471_08255	COG1923	regulation of RNA biosynthetic process
DY471_08265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DY471_08270	COG1360	Flagellar Motor Protein
DY471_08275	COG2201	protein-glutamate methylesterase activity
DY471_08280	COG0643	Histidine kinase
DY471_08280	COG2198	Histidine kinase
DY471_08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DY471_08285	COG1776	CheC inhibitor of MCP methylation
DY471_08300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DY471_08320	COG1256	bacterial-type flagellum assembly
DY471_08325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DY471_08345	COG1815	bacterial-type flagellum-dependent cell motility
DY471_08350	COG1558	bacterial-type flagellum-dependent cell motility
DY471_08355	COG1677	Flagellar hook-basal body complex protein FliE
DY471_08360	COG1766	The M ring may be actively involved in energy transduction
DY471_08365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DY471_08375	COG1157	protein secretion by the type III secretion system
DY471_08410	COG0784	Response regulator, receiver
DY471_08410	COG0835	chemotaxis
DY471_08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DY471_08425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DY471_08430	COG0741	lytic transglycosylase activity
DY471_08440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DY471_08445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DY471_08445	COG1776	CheC inhibitor of MCP methylation
DY471_08455	COG1338	Plays a role in the flagellum-specific transport system
DY471_08460	COG1987	bacterial-type flagellum assembly
DY471_08470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DY471_08475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DY471_08480	COG1419	protein localization to endoplasmic reticulum
DY471_08485	COG4786	Flagellar basal body rod
DY471_08490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DY471_08525	COG2329	Antibiotic biosynthesis monooxygenase
DY471_08555	COG3842	ATPase activity
DY471_08560	COG0725	ABC transporter, periplasmic molybdate-binding protein
DY471_08570	COG1234	tRNA 3'-trailer cleavage
DY471_08600	COG1686	Belongs to the peptidase S11 family
DY471_08630	COG1846	Transcriptional regulator
DY471_08640	COG0367	asparagine synthase
DY471_08670	COG1802	Transcriptional regulator
DY471_08675	COG0697	spore germination
DY471_08680	COG0523	cobalamin synthesis protein
DY471_08695	COG1216	Glycosyl transferase, family 2
DY471_08695	COG0438	transferase activity, transferring glycosyl groups
DY471_08700	COG1757	Na H antiporter
DY471_08705	COG0114	fumarate hydratase activity
DY471_08725	COG0534	Mate efflux family protein
DY471_08730	COG3340	Belongs to the peptidase S51 family
DY471_08750	COG0785	Cytochrome C biogenesis protein
DY471_08775	COG2733	membrane
DY471_08815	COG1131	(ABC) transporter
DY471_08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DY471_08835	COG0528	UMP kinase activity
DY471_08845	COG1027	Aspartate ammonia-lyase
DY471_08850	COG0281	malic enzyme
DY471_08855	COG4191	Histidine kinase
DY471_08860	COG0784	Response regulator, receiver
DY471_08865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DY471_08885	COG3620	sequence-specific DNA binding
DY471_08940	COG1966	Carbon starvation protein
DY471_08950	COG0477	Major facilitator Superfamily
DY471_08955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DY471_08970	COG4166	transmembrane transport
DY471_08975	COG2223	nitrite transmembrane transporter activity
DY471_08980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DY471_08995	COG2244	polysaccharide biosynthetic process
DY471_09000	COG0733	neurotransmitter:sodium symporter activity
DY471_09010	COG5566	PFAM Mor transcription activator
DY471_09015	COG2323	membrane
DY471_09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DY471_09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DY471_09045	COG0028	Belongs to the TPP enzyme family
DY471_09055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DY471_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DY471_09090	COG2814	Major facilitator Superfamily
DY471_09095	COG3384	dioxygenase
DY471_09105	COG3279	Response regulator of the LytR AlgR family
DY471_09110	COG0427	acetyl-CoA hydrolase
DY471_09130	COG1073	alpha beta
DY471_09135	COG4166	transmembrane transport
DY471_09175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_09205	COG1914	H( )-stimulated, divalent metal cation uptake system
DY471_09220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DY471_09225	COG0531	amino acid
DY471_09260	COG0714	Associated with various cellular activities
DY471_09270	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DY471_09295	COG2390	Transcriptional regulator
DY471_09305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_09310	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DY471_09320	COG4846	Membrane protein involved in cytochrome C biogenesis
DY471_09330	COG0006	proline dipeptidase activity
DY471_09385	COG1114	Component of the transport system for branched-chain amino acids
DY471_09395	COG2372	response to copper ion
DY471_09395	COG1276	copper resistance
DY471_09400	COG4549	nuclear export factor GLE1
DY471_09405	COG0697	spore germination
DY471_09410	COG0583	DNA-binding transcription factor activity
DY471_09415	COG1959	2 iron, 2 sulfur cluster binding
DY471_09420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DY471_09425	COG0778	Nitroreductase
DY471_09435	COG0628	permease
DY471_09445	COG1231	oxidoreductase activity
DY471_09450	COG0523	cobalamin synthesis protein
DY471_09460	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_09465	COG2030	dehydratase
DY471_09470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_09480	COG0411	ABC transporter
DY471_09490	COG0559	Belongs to the binding-protein-dependent transport system permease family
DY471_09500	COG0583	DNA-binding transcription factor activity
DY471_09510	COG1942	4-Oxalocrotonate Tautomerase
DY471_09535	COG1271	oxidase subunit
DY471_09540	COG1294	oxidase, subunit
DY471_09545	COG4988	ABC transporter
DY471_09550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DY471_09570	COG1619	proteins homologs of microcin C7 resistance protein MccF
DY471_09575	COG1686	Belongs to the peptidase S11 family
DY471_09590	COG1388	LysM domain
DY471_09590	COG0791	NLP P60 protein
DY471_09600	COG1132	(ABC) transporter
DY471_09605	COG0745	RESPONSE REGULATOR receiver
DY471_09610	COG5002	protein histidine kinase activity
DY471_09615	COG2205	protein histidine kinase activity
DY471_09620	COG0745	RESPONSE REGULATOR receiver
DY471_09645	COG0300	oxidoreductase activity
DY471_09660	COG0726	polysaccharide deacetylase
DY471_09685	COG0460	homoserine dehydrogenase
DY471_09710	COG1316	TRANSCRIPTIONal
DY471_09720	COG0745	RESPONSE REGULATOR receiver
DY471_09725	COG5002	protein histidine kinase activity
DY471_09730	COG0726	polysaccharide deacetylase
DY471_09740	COG1285	pathogenesis
DY471_09745	COG1247	-acetyltransferase
DY471_09755	COG4264	IucA IucC family
DY471_09760	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_09775	COG1082	Xylose isomerase domain protein TIM barrel
DY471_09785	COG2814	Major facilitator Superfamily
DY471_09790	COG1279	arginine transmembrane transporter activity
DY471_09795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_09805	COG1752	Esterase of the alpha-beta hydrolase superfamily
DY471_09840	COG0577	efflux transmembrane transporter activity
DY471_09845	COG2002	toxin-antitoxin pair type II binding
DY471_09850	COG1404	Belongs to the peptidase S8 family
DY471_09855	COG0640	Transcriptional regulator
DY471_09860	COG0667	Aldo Keto reductase
DY471_09865	COG2814	Major facilitator Superfamily
DY471_09890	COG0840	transmembrane signaling receptor activity
DY471_09905	COG3949	Membrane
DY471_09910	COG0783	Belongs to the Dps family
DY471_09925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DY471_09935	COG1231	oxidoreductase activity
DY471_09945	COG4989	oxidoreductase activity
DY471_09955	COG0523	cobalamin synthesis protein
DY471_09960	COG0456	acetyltransferase
DY471_09965	COG0803	Belongs to the bacterial solute-binding protein 9 family
DY471_09965	COG3443	Belongs to the bacterial solute-binding protein 9 family
DY471_09970	COG0702	epimerase
DY471_09980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DY471_09990	COG4166	transmembrane transport
DY471_10005	COG0406	alpha-ribazole phosphatase activity
DY471_10015	COG5337	Spore coat protein CotH
DY471_10020	COG1051	belongs to the nudix hydrolase family
DY471_10025	COG0586	Pfam SNARE associated Golgi protein
DY471_10030	COG2244	polysaccharide biosynthetic process
DY471_10040	COG0701	Predicted permease
DY471_10045	COG3689	TIGRFAM TIGR03943 family protein
DY471_10050	COG1607	acyl-coa hydrolase
DY471_10060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DY471_10075	COG0702	epimerase
DY471_10080	COG2839	Protein conserved in bacteria
DY471_10085	COG1253	flavin adenine dinucleotide binding
DY471_10100	COG1114	Component of the transport system for branched-chain amino acids
DY471_10105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DY471_10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
DY471_10140	COG1876	peptidase activity
DY471_10150	COG0154	amidase activity
DY471_10155	COG2211	Major facilitator Superfamily
DY471_10170	COG2368	4-hydroxyphenylacetate
DY471_10180	COG0196	riboflavin kinase activity
DY471_10195	COG0251	oxidation-reduction process
DY471_10225	COG1942	4-Oxalocrotonate Tautomerase
DY471_10235	COG0561	phosphatase activity
DY471_10245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DY471_10265	COG1819	glycosyl
DY471_10270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_10305	COG0456	acetyltransferase
DY471_10390	COG3874	Sporulation protein YtfJ
DY471_10415	COG2226	methyltransferase
DY471_10435	COG1082	Xylose isomerase domain protein TIM barrel
DY471_10440	COG0346	lactoylglutathione lyase activity
DY471_10445	COG0582	viral genome integration into host DNA
DY471_10460	COG1396	sequence-specific DNA binding
DY471_10565	COG0582	viral genome integration into host DNA
DY471_10605	COG1802	Transcriptional regulator
DY471_10605	COG4626	Terminase
DY471_10615	COG0740	serine-type endopeptidase activity
DY471_10695	COG4824	toxin secretion phage lysis holin
DY471_10700	COG5632	N-Acetylmuramoyl-L-alanine amidase
DY471_10700	COG1388	LysM domain
DY471_10700	COG3409	Peptidoglycan-binding domain 1 protein
DY471_10745	COG0604	alcohol dehydrogenase
DY471_10750	COG1595	DNA-templated transcription, initiation
DY471_10775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DY471_10775	COG0426	domain, Protein
DY471_10800	COG0386	Belongs to the glutathione peroxidase family
DY471_10805	COG1305	Transglutaminase-like
DY471_10810	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DY471_10815	COG0714	Associated with various cellular activities
DY471_10830	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DY471_10835	COG1140	nitrate reductase beta subunit
DY471_10840	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DY471_10845	COG2181	nitrate reductase activity
DY471_10850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DY471_10855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DY471_10865	COG0303	'Molybdopterin
DY471_10870	COG0314	molybdopterin synthase activity
DY471_10880	COG2223	nitrite transmembrane transporter activity
DY471_10895	COG1648	precorrin-2 dehydrogenase activity
DY471_10905	COG1587	Uroporphyrinogen-III synthase
DY471_10905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DY471_10910	COG2146	nitrite reductase [NAD(P)H] activity
DY471_10915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DY471_10920	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DY471_10955	COG2359	stage V sporulation protein S
DY471_11010	COG1418	mRNA catabolic process
DY471_11015	COG0488	(ABC) transporter
DY471_11030	COG0629	single-stranded DNA binding
DY471_11035	COG1413	lyase activity
DY471_11050	COG2521	methyltransferase
DY471_11050	COG2136	Putative SAM-dependent methyltransferase
DY471_11110	COG0017	Asparaginyl-tRNA synthetase
DY471_11130	COG1674	ftsk spoiiie
DY471_11225	COG0733	neurotransmitter:sodium symporter activity
DY471_11250	COG2610	gluconate transmembrane transporter activity
DY471_11255	COG1454	alcohol dehydrogenase
DY471_11260	COG1794	racemase activity, acting on amino acids and derivatives
DY471_11270	COG0456	acetyltransferase
DY471_11275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DY471_11285	COG1131	(ABC) transporter
DY471_11290	COG4473	ABC transporter
DY471_11300	COG0546	phosphoglycolate phosphatase activity
DY471_11320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DY471_11335	COG0768	penicillin binding
DY471_11345	COG0204	Acyl-transferase
DY471_11350	COG1272	protein, Hemolysin III
DY471_11360	COG0805	protein transport
DY471_11370	COG1307	EDD domain protein, DegV family
DY471_11375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DY471_11380	COG1999	signal sequence binding
DY471_11385	COG0071	Belongs to the small heat shock protein (HSP20) family
DY471_11390	COG0367	asparagine synthase
DY471_11410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_11415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DY471_11435	COG1335	isochorismatase
DY471_11440	COG1051	belongs to the nudix hydrolase family
DY471_11445	COG0071	Belongs to the small heat shock protein (HSP20) family
DY471_11450	COG0668	transmembrane transport
DY471_11455	COG4585	Histidine kinase
DY471_11455	COG2203	Gaf domain
DY471_11460	COG2197	response regulator
DY471_11465	COG1737	Transcriptional regulator
DY471_11470	COG1064	alcohol dehydrogenase
DY471_11495	COG1070	Carbohydrate kinase
DY471_11530	COG0517	IMP dehydrogenase activity
DY471_11530	COG1125	glycine betaine transport
DY471_11535	COG1174	glycine betaine transport
DY471_11570	COG1253	flavin adenine dinucleotide binding
DY471_11575	COG1012	belongs to the aldehyde dehydrogenase family
DY471_11580	COG5506	Protein of unknown function (DUF1694)
DY471_11595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DY471_11600	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DY471_11605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DY471_11610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DY471_11615	COG0456	acetyltransferase
DY471_11620	COG3829	transcription factor binding
DY471_11630	COG1509	lysine 2,3-aminomutase activity
DY471_11665	COG4991	sh3 domain protein
DY471_11665	COG0515	serine threonine protein kinase
DY471_11665	COG3064	Membrane
DY471_11670	COG4326	sporulation control protein
DY471_11675	COG0671	phosphoesterase, PA-phosphatase related
DY471_11680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DY471_11685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DY471_11755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DY471_11800	COG4499	WXG100 protein secretion system (Wss), protein YukC
DY471_11800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DY471_11810	COG2814	Major facilitator Superfamily
DY471_11815	COG4841	protein insertion into membrane
DY471_11820	COG0372	Belongs to the citrate synthase family
DY471_11825	COG2079	MmgE PrpD family protein
DY471_11830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DY471_11835	COG1960	acyl-CoA dehydrogenase activity
DY471_11840	COG2084	Dehydrogenase
DY471_11845	COG1012	belongs to the aldehyde dehydrogenase family
DY471_11850	COG1280	lysine exporter protein (LysE YggA)
DY471_11855	COG1024	Enoyl-CoA hydratase
DY471_11870	COG0420	3'-5' exonuclease activity
DY471_11895	COG2223	nitrite transmembrane transporter activity
DY471_11905	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_11910	COG1169	isochorismate synthase
DY471_11915	COG1021	2,3-dihydroxybenzoate-AMP ligase
DY471_11920	COG1535	isochorismatase
DY471_11920	COG3433	isochorismatase activity
DY471_11925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DY471_11930	COG3251	PFAM MbtH domain protein
DY471_11935	COG2814	Major facilitator Superfamily
DY471_11950	COG0776	regulation of translation
DY471_11960	COG2318	DinB family
DY471_11970	COG1115	amino acid carrier protein
DY471_11985	COG2329	Antibiotic biosynthesis monooxygenase
DY471_11990	COG1187	pseudouridine synthase activity
DY471_11995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DY471_12000	COG1136	(ABC) transporter
DY471_12010	COG0596	Alpha beta hydrolase
DY471_12015	COG2814	Major facilitator Superfamily
DY471_12030	COG0028	Belongs to the TPP enzyme family
DY471_12075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_12110	COG1247	-acetyltransferase
DY471_12150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_12160	COG1278	Cold shock
DY471_12175	COG0010	Belongs to the arginase family
DY471_12180	COG0561	phosphatase activity
DY471_12190	COG1846	Transcriptional regulator
DY471_12195	COG2814	Major facilitator Superfamily
DY471_12200	COG0583	DNA-binding transcription factor activity
DY471_12205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DY471_12220	COG0583	DNA-binding transcription factor activity
DY471_12225	COG2258	MOSC domain
DY471_12240	COG1132	(ABC) transporter
DY471_12245	COG1132	(ABC) transporter
DY471_12265	COG1396	sequence-specific DNA binding
DY471_12295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DY471_12310	COG1595	DNA-templated transcription, initiation
DY471_12330	COG1649	PFAM Uncharacterised BCR, COG1649
DY471_12355	COG2971	BadF BadG BcrA BcrD
DY471_12365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DY471_12385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_12415	COG1309	transcriptional regulator
DY471_12430	COG0577	efflux transmembrane transporter activity
DY471_12430	COG1136	(ABC) transporter
DY471_12435	COG3615	Tellurite resistance protein tehB
DY471_12435	COG0500	methyltransferase
DY471_12445	COG3961	Belongs to the TPP enzyme family
DY471_12450	COG1846	Transcriptional regulator
DY471_12480	COG2195	Cleaves the N-terminal amino acid of tripeptides
DY471_12490	COG0110	maltose O-acetyltransferase activity
DY471_12500	COG0768	penicillin binding
DY471_12505	COG1595	DNA-templated transcription, initiation
DY471_12515	COG0768	penicillin binding
DY471_12525	COG2367	Beta-lactamase
DY471_12535	COG1609	Transcriptional regulator
DY471_12540	COG2814	Major facilitator Superfamily
DY471_12545	COG0673	inositol 2-dehydrogenase activity
DY471_12575	COG3718	enzyme involved in inositol metabolism
DY471_12590	COG3773	Cell wall hydrolase
DY471_12605	COG2755	lipolytic protein G-D-S-L family
DY471_12605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DY471_12625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_12670	COG1131	(ABC) transporter
DY471_12685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_12715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DY471_12770	COG0584	glycerophosphoryl diester phosphodiesterase
DY471_12800	COG1131	(ABC) transporter
DY471_12810	COG1309	transcriptional regulator
DY471_12825	COG1960	acyl-CoA dehydrogenase activity
DY471_12830	COG0439	Biotin carboxylase
DY471_12835	COG0511	ligase activity, forming carbon-carbon bonds
DY471_12840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DY471_12845	COG1024	Enoyl-CoA hydratase
DY471_12850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DY471_12855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DY471_12865	COG1247	-acetyltransferase
DY471_12870	COG0572	uridine kinase
DY471_12880	COG2318	DinB family
DY471_12885	COG1686	Belongs to the peptidase S11 family
DY471_12910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DY471_12930	COG3227	Zinc metalloprotease (Elastase)
DY471_12935	COG2207	Transcriptional regulator
DY471_12975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DY471_12980	COG0789	Transcriptional regulator
DY471_13015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DY471_13035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_13050	COG1063	alcohol dehydrogenase
DY471_13055	COG2323	membrane
DY471_13070	COG3386	PFAM SMP-30 Gluconolaconase
DY471_13080	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DY471_13085	COG3773	Cell wall hydrolase
DY471_13095	COG0745	RESPONSE REGULATOR receiver
DY471_13100	COG2205	protein histidine kinase activity
DY471_13120	COG1136	(ABC) transporter
DY471_13125	COG0577	efflux transmembrane transporter activity
DY471_13145	COG0460	homoserine dehydrogenase
DY471_13150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_13160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DY471_13210	COG2124	cytochrome p450
DY471_13245	COG0561	phosphatase activity
DY471_13250	COG5002	protein histidine kinase activity
DY471_13260	COG1819	glycosyl
DY471_13265	COG1794	racemase activity, acting on amino acids and derivatives
DY471_13290	COG2205	protein histidine kinase activity
DY471_13300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DY471_13305	COG0604	alcohol dehydrogenase
DY471_13310	COG0671	phosphoesterase, PA-phosphatase related
DY471_13325	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_13375	COG0693	protein deglycase activity
DY471_13405	COG0789	Transcriptional regulator
DY471_13415	COG2814	Major facilitator Superfamily
DY471_13430	COG0584	glycerophosphoryl diester phosphodiesterase
DY471_13450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_13455	COG0697	spore germination
DY471_13480	COG2223	nitrite transmembrane transporter activity
DY471_13495	COG2816	NAD+ diphosphatase activity
DY471_13500	COG0592	DNA-directed DNA polymerase activity
DY471_13505	COG1051	belongs to the nudix hydrolase family
DY471_13540	COG3878	Protein conserved in bacteria
DY471_13560	COG4667	esterase of the alpha-beta hydrolase superfamily
DY471_13585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DY471_13600	COG0322	excinuclease ABC activity
DY471_13635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DY471_13655	COG1011	Hydrolase
DY471_13680	COG1523	belongs to the glycosyl hydrolase 13 family
DY471_13685	COG3227	Zinc metalloprotease (Elastase)
DY471_13705	COG0346	lactoylglutathione lyase activity
DY471_13710	COG0201	protein transport
DY471_13720	COG0697	spore germination
DY471_13725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_13765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_13780	COG2959	enzyme of heme biosynthesis
DY471_13785	COG3409	Peptidoglycan-binding domain 1 protein
DY471_13785	COG3773	Cell wall hydrolase
DY471_13815	COG1309	transcriptional regulator
DY471_13850	COG3284	Transcriptional regulator
DY471_13865	COG1349	DNA-binding transcription factor activity
DY471_13885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DY471_13890	COG0508	dehydrogenase complex catalyzes the overall conversion of
DY471_13895	COG0022	dehydrogenase e1 component
DY471_13900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DY471_13910	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_13915	COG0456	acetyltransferase
DY471_13915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DY471_13950	COG4176	ABC-type proline glycine betaine transport system permease component
DY471_13955	COG4175	Glycine betaine
DY471_13955	COG0517	IMP dehydrogenase activity
DY471_13980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DY471_13985	COG2153	protein acetylation
DY471_13990	COG3397	chitin binding
DY471_13995	COG1819	glycosyl
DY471_14015	COG2205	protein histidine kinase activity
DY471_14020	COG2226	methyltransferase
DY471_14055	COG3973	AAA domain
DY471_14070	COG2105	PFAM AIG2 family protein
DY471_14075	COG0514	ATP-dependent DNA helicase (RecQ)
DY471_14100	COG4637	Psort location Cytoplasmic, score
DY471_14120	COG3397	chitin binding
DY471_14135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DY471_14140	COG1115	amino acid carrier protein
DY471_14145	COG1012	belongs to the aldehyde dehydrogenase family
DY471_14150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DY471_14160	COG3938	Belongs to the proline racemase family
DY471_14165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DY471_14205	COG0586	Pfam SNARE associated Golgi protein
DY471_14220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DY471_14225	COG0519	Catalyzes the synthesis of GMP from XMP
DY471_14230	COG4166	transmembrane transport
DY471_14240	COG4948	Mandelate Racemase Muconate Lactonizing
DY471_14300	COG2936	dipeptidyl-peptidase activity
DY471_14305	COG5002	protein histidine kinase activity
DY471_14310	COG0745	RESPONSE REGULATOR receiver
DY471_14340	COG1164	Oligoendopeptidase f
DY471_14345	COG0531	amino acid
DY471_14350	COG1522	sequence-specific DNA binding
DY471_14365	COG1307	EDD domain protein, DegV family
DY471_14405	COG2814	Major facilitator Superfamily
DY471_14415	COG1664	Polymer-forming cytoskeletal
DY471_14420	COG0789	Transcriptional regulator
DY471_14425	COG4533	DNA binding
DY471_14430	COG2814	Major facilitator Superfamily
DY471_14430	COG0477	Major facilitator Superfamily
DY471_14450	COG2261	transglycosylase associated protein
DY471_14465	COG2226	methyltransferase
DY471_14500	COG0436	Aminotransferase
DY471_14505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DY471_14515	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DY471_14530	COG1131	(ABC) transporter
DY471_14580	COG0628	permease
DY471_14590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DY471_14595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DY471_14600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DY471_14645	COG2746	aminoglycoside 3-N-acetyltransferase activity
DY471_14665	COG0697	spore germination
DY471_14670	COG2318	DinB family
DY471_14690	COG4912	Dna alkylation repair
DY471_14695	COG0726	polysaccharide deacetylase
DY471_14700	COG3037	sugar-specific permease SgaT UlaA
DY471_14710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DY471_14715	COG0861	Integral membrane protein TerC family
DY471_14720	COG1368	sulfuric ester hydrolase activity
DY471_14730	COG0488	(ABC) transporter
DY471_14740	COG1033	growth of symbiont in host cell
DY471_14740	COG2409	Drug exporters of the RND superfamily
DY471_14745	COG1309	transcriptional regulator
DY471_14760	COG0287	Prephenate dehydrogenase
DY471_14775	COG1605	Chorismate mutase
DY471_14775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DY471_14820	COG2610	gluconate transmembrane transporter activity
DY471_14825	COG1024	Enoyl-CoA hydratase
DY471_14835	COG3829	transcription factor binding
DY471_14835	COG3290	protein histidine kinase activity
DY471_14850	COG1879	ABC-type sugar transport system periplasmic component
DY471_14860	COG1172	Belongs to the binding-protein-dependent transport system permease family
DY471_14870	COG2390	Transcriptional regulator
DY471_14875	COG1070	Carbohydrate kinase
DY471_14910	COG2329	Antibiotic biosynthesis monooxygenase
DY471_14930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_14940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DY471_14945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DY471_14960	COG4187	Peptidase family M20/M25/M40
DY471_14965	COG1414	Transcriptional regulator
DY471_14975	COG0833	amino acid
DY471_14980	COG1690	Belongs to the RtcB family
DY471_14985	COG3239	Fatty acid desaturase
DY471_14990	COG1785	Belongs to the alkaline phosphatase family
DY471_15000	COG3655	Transcriptional regulator
DY471_15015	COG4377	Putative membrane peptidase family (DUF2324)
DY471_15025	COG3279	Response regulator of the LytR AlgR family
DY471_15035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_15040	COG0346	lactoylglutathione lyase activity
DY471_15065	COG0714	Associated with various cellular activities
DY471_15090	COG0463	Glycosyl transferase, family 2
DY471_15110	COG0463	Glycosyl transferase, family 2
DY471_15120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DY471_15125	COG0753	catalase activity
DY471_15135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DY471_15145	COG1280	lysine exporter protein (LysE YggA)
DY471_15150	COG3403	YqcI/YcgG family
DY471_15180	COG0714	Associated with various cellular activities
DY471_15190	COG0778	Nitroreductase
DY471_15195	COG1846	Transcriptional regulator
DY471_15230	COG1136	(ABC) transporter
DY471_15260	COG0456	acetyltransferase
DY471_15280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_15330	COG0730	response to heat
DY471_15340	COG0833	amino acid
DY471_15350	COG4335	DNA alkylation repair
DY471_15420	COG1984	allophanate hydrolase subunit 2
DY471_15425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DY471_15430	COG1414	Transcriptional regulator
DY471_15445	COG0860	N-Acetylmuramoyl-L-alanine amidase
DY471_15450	COG0640	Transcriptional regulator
DY471_15460	COG1960	acyl-CoA dehydrogenase activity
DY471_15485	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DY471_15500	COG3848	Pyruvate phosphate dikinase
DY471_15500	COG0574	Belongs to the PEP-utilizing enzyme family
DY471_15510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_15515	COG5577	PFAM Coat F domain
DY471_15520	COG3403	YqcI/YcgG family
DY471_15525	COG1280	lysine exporter protein (LysE YggA)
DY471_15530	COG1113	amino acid transport
DY471_15555	COG1063	alcohol dehydrogenase
DY471_15565	COG1027	Aspartate ammonia-lyase
DY471_15570	COG0252	asparaginase activity
DY471_15575	COG1396	sequence-specific DNA binding
DY471_15580	COG2801	Transposase and inactivated derivatives
DY471_15585	COG0322	excinuclease ABC activity
DY471_15590	COG0531	amino acid
DY471_15595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DY471_15605	COG0531	amino acid
DY471_15610	COG0697	spore germination
DY471_15620	COG0784	Response regulator, receiver
DY471_15625	COG4191	Histidine kinase
DY471_15630	COG2066	Belongs to the glutaminase family
DY471_15635	COG1115	amino acid carrier protein
DY471_15665	COG0737	Belongs to the 5'-nucleotidase family
DY471_15670	COG0753	catalase activity
DY471_15675	COG2267	carboxylic ester hydrolase activity
DY471_15680	COG1335	isochorismatase
DY471_15700	COG0583	DNA-binding transcription factor activity
DY471_15715	COG0598	Magnesium transport protein CorA
DY471_15775	COG0415	Belongs to the DNA photolyase family
DY471_15780	COG0288	reversible hydration of carbon dioxide
DY471_15790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DY471_15795	COG5609	conserved protein (DUF2294)
DY471_15815	COG0697	spore germination
DY471_15830	COG1575	Belongs to the MenA family. Type 1 subfamily
DY471_15835	COG2267	carboxylic ester hydrolase activity
DY471_15840	COG4641	Protein conserved in bacteria
DY471_15845	COG1136	(ABC) transporter
DY471_15850	COG0577	efflux transmembrane transporter activity
DY471_15900	COG0798	PFAM Bile acid sodium symporter
DY471_15905	COG0346	lactoylglutathione lyase activity
DY471_15910	COG0640	Transcriptional regulator
DY471_15925	COG0443	Heat shock 70 kDa protein
DY471_15940	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_15960	COG0346	lactoylglutathione lyase activity
DY471_15980	COG2169	Transcriptional regulator
DY471_16020	COG2814	Major facilitator Superfamily
DY471_16090	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DY471_16115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DY471_16130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_16160	COG0789	Transcriptional regulator
DY471_16165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DY471_16185	COG0577	efflux transmembrane transporter activity
DY471_16200	COG5002	protein histidine kinase activity
DY471_16200	COG3850	Histidine kinase
DY471_16210	COG2364	Membrane
DY471_16215	COG1846	Transcriptional regulator
DY471_16220	COG0456	acetyltransferase
DY471_16225	COG2808	Putative FMN-binding domain
DY471_16230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_16245	COG1619	proteins homologs of microcin C7 resistance protein MccF
DY471_16260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DY471_16280	COG0662	Cupin 2, conserved barrel domain protein
DY471_16290	COG2207	Transcriptional regulator
DY471_16290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_16310	COG5632	N-Acetylmuramoyl-L-alanine amidase
DY471_16310	COG3409	Peptidoglycan-binding domain 1 protein
DY471_16350	COG0477	Major facilitator Superfamily
DY471_16365	COG1846	Transcriptional regulator
DY471_16370	COG2814	Major facilitator Superfamily
DY471_16385	COG2076	Multidrug Resistance protein
DY471_16390	COG1309	transcriptional regulator
DY471_16400	COG2031	fatty acid transporter
DY471_16410	COG2249	NAD(P)H dehydrogenase (quinone) activity
DY471_16440	COG1122	ATPase activity
DY471_16445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DY471_16460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DY471_16465	COG1288	antiporter activity
DY471_16485	COG0789	Transcriptional regulator
DY471_16500	COG3620	sequence-specific DNA binding
DY471_16510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DY471_16530	COG1733	regulation of RNA biosynthetic process
DY471_16535	COG0778	Nitroreductase
DY471_16555	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_16565	COG1131	(ABC) transporter
DY471_16595	COG1011	Hydrolase
DY471_16635	COG0346	lactoylglutathione lyase activity
DY471_16640	COG1940	carbohydrate kinase activity
DY471_16645	COG0738	Major facilitator superfamily
DY471_16650	COG0110	maltose O-acetyltransferase activity
DY471_16660	COG0577	efflux transmembrane transporter activity
DY471_16660	COG1136	(ABC) transporter
DY471_16665	COG0180	Tryptophanyl-tRNA synthetase
DY471_16675	COG0628	permease
DY471_16690	COG2226	methyltransferase
DY471_16700	COG0477	Major facilitator Superfamily
DY471_16730	COG1253	flavin adenine dinucleotide binding
DY471_16735	COG0789	Transcriptional regulator
DY471_16745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DY471_16775	COG0697	spore germination
DY471_16780	COG1357	PFAM Pentapeptide repeats (8 copies)
DY471_16785	COG3813	Protein conserved in bacteria
DY471_16790	COG2706	6-phosphogluconolactonase activity
DY471_16795	COG1070	Carbohydrate kinase
DY471_16805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DY471_16810	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DY471_16820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DY471_16825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DY471_16830	COG0604	alcohol dehydrogenase
DY471_16835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DY471_16850	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_16865	COG0840	transmembrane signaling receptor activity
DY471_16875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DY471_16875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DY471_16880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DY471_16885	COG1733	regulation of RNA biosynthetic process
DY471_16905	COG0656	L-ascorbic acid biosynthetic process
DY471_16910	COG2814	Major facilitator Superfamily
DY471_16925	COG0346	lactoylglutathione lyase activity
DY471_16930	COG0814	amino acid
DY471_16955	COG1393	Belongs to the ArsC family
DY471_16960	COG1733	regulation of RNA biosynthetic process
DY471_16965	COG2188	Transcriptional regulator
DY471_16970	COG0673	inositol 2-dehydrogenase activity
DY471_16975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DY471_16980	COG1733	regulation of RNA biosynthetic process
DY471_16985	COG1733	regulation of RNA biosynthetic process
DY471_17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_17025	COG0384	phenazine biosynthesis protein PhzF
DY471_17035	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_17045	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_17050	COG2249	NAD(P)H dehydrogenase (quinone) activity
DY471_17055	COG1733	regulation of RNA biosynthetic process
DY471_17065	COG0726	polysaccharide deacetylase
DY471_17075	COG1191	sigma factor activity
DY471_17100	COG1309	transcriptional regulator
DY471_17120	COG3152	Membrane
DY471_17145	COG1151	hydroxylamine reductase activity
DY471_17155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_17160	COG3757	hydrolase, family 25
DY471_17160	COG3409	Peptidoglycan-binding domain 1 protein
DY471_17195	COG2072	flavoprotein involved in K transport
DY471_17240	COG0714	Associated with various cellular activities
DY471_17280	COG0604	alcohol dehydrogenase
DY471_17285	COG1113	amino acid transport
DY471_17290	COG2814	Major facilitator Superfamily
DY471_17320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DY471_17325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DY471_17340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_17345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_17350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_17355	COG3739	integral membrane protein
DY471_17360	COG0384	phenazine biosynthesis protein PhzF
DY471_17395	COG0583	DNA-binding transcription factor activity
DY471_17405	COG2890	protein-(glutamine-N5) methyltransferase activity
DY471_17420	COG1193	negative regulation of DNA recombination
DY471_17435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DY471_17440	COG1164	Oligoendopeptidase f
DY471_17445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DY471_17480	COG0584	glycerophosphoryl diester phosphodiesterase
DY471_17505	COG0640	Transcriptional regulator
DY471_17510	COG0604	alcohol dehydrogenase
DY471_17520	COG0457	Tetratricopeptide repeat
DY471_17530	COG2808	Putative FMN-binding domain
DY471_17545	COG0385	Bile acid
DY471_17550	COG0277	FAD linked oxidase domain protein
DY471_17585	COG1216	Glycosyl transferase, family 2
DY471_17590	COG1024	Enoyl-CoA hydratase
DY471_17600	COG1285	pathogenesis
DY471_17615	COG2514	catechol 2,3-dioxygenase activity
DY471_17620	COG2720	vancomycin resistance protein
DY471_17650	COG1278	Cold shock
DY471_17660	COG0716	FMN binding
DY471_17690	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_17700	COG0165	Argininosuccinate lyase
DY471_17715	COG4145	pantothenate transmembrane transporter activity
DY471_17725	COG1012	belongs to the aldehyde dehydrogenase family
DY471_17730	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_17740	COG1657	PFAM Prenyltransferase squalene oxidase
DY471_17745	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DY471_17750	COG2962	Rard protein
DY471_17755	COG3326	Membrane
DY471_17770	COG0489	protein tyrosine kinase activity
DY471_17780	COG0314	molybdopterin synthase activity
DY471_17785	COG0303	'Molybdopterin
DY471_17790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DY471_17795	COG2116	formate transmembrane transporter activity
DY471_17805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DY471_17810	COG5609	conserved protein (DUF2294)
DY471_17815	COG2427	Protein of unknown function (DUF1641)
DY471_17820	COG3383	formate dehydrogenase (NAD+) activity
DY471_17825	COG0697	spore germination
DY471_17840	COG0531	amino acid
DY471_17880	COG2226	methyltransferase
DY471_17885	COG4166	transmembrane transport
DY471_17890	COG4166	transmembrane transport
DY471_17895	COG4166	transmembrane transport
DY471_17900	COG1301	dicarboxylic acid transport
DY471_17905	COG1316	TRANSCRIPTIONal
DY471_17915	COG1595	DNA-templated transcription, initiation
DY471_17930	COG1131	(ABC) transporter
DY471_17940	COG0673	inositol 2-dehydrogenase activity
DY471_17945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DY471_17950	COG0187	DNA topoisomerase II activity
DY471_17955	COG1832	CoA-binding protein
DY471_17960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DY471_17965	COG0745	RESPONSE REGULATOR receiver
DY471_17985	COG4841	protein insertion into membrane
DY471_17990	COG0824	Thioesterase
DY471_18020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DY471_18035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DY471_18045	COG0726	polysaccharide deacetylase
DY471_18065	COG2211	Major facilitator Superfamily
DY471_18075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DY471_18090	COG0183	Belongs to the thiolase family
DY471_18095	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_18100	COG1268	BioY protein
DY471_18105	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_18120	COG1396	sequence-specific DNA binding
DY471_18175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_18190	COG5002	protein histidine kinase activity
DY471_18195	COG0400	carboxylic ester hydrolase activity
DY471_18200	COG0346	lactoylglutathione lyase activity
DY471_18205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DY471_18210	COG0069	glutamate synthase activity
DY471_18215	COG1902	pentaerythritol trinitrate reductase activity
DY471_18220	COG1329	Transcriptional regulator
DY471_18225	COG0010	Belongs to the arginase family
DY471_18290	COG4846	Membrane protein involved in cytochrome C biogenesis
DY471_18295	COG0785	Cytochrome C biogenesis protein
DY471_18320	COG1131	(ABC) transporter
DY471_18330	COG0583	DNA-binding transcription factor activity
DY471_18340	COG1346	cytolysis
DY471_18355	COG0730	response to heat
DY471_18380	COG1132	(ABC) transporter
DY471_18385	COG1132	(ABC) transporter
DY471_18430	COG0737	Belongs to the 5'-nucleotidase family
DY471_18440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DY471_18460	COG1695	Transcriptional regulator
DY471_18600	COG0740	serine-type endopeptidase activity
DY471_18610	COG1802	Transcriptional regulator
DY471_18610	COG4626	Terminase
DY471_18640	COG0582	viral genome integration into host DNA
DY471_18705	COG1484	DNA-dependent DNA replication
DY471_18770	COG0174	glutamine synthetase
DY471_18775	COG0789	Transcriptional regulator
DY471_18780	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DY471_18785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DY471_18790	COG2860	membrane
DY471_18795	COG0464	growth
DY471_18825	COG3584	3D domain protein
DY471_18825	COG1388	LysM domain
DY471_18830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DY471_18830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DY471_18830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DY471_18835	COG1105	Belongs to the carbohydrate kinase PfkB family
DY471_18840	COG1349	DNA-binding transcription factor activity
DY471_18845	COG1979	alcohol dehydrogenase
DY471_18850	COG2322	membrane
DY471_18860	COG1113	amino acid transport
DY471_18875	COG1408	metallophosphoesterase
DY471_18880	COG2116	formate transmembrane transporter activity
DY471_18895	COG2217	Heavy metal translocating P-type atpase
DY471_18900	COG2608	mercury ion transmembrane transporter activity
DY471_18905	COG1937	Protein conserved in bacteria
DY471_18915	COG2819	hydrolase of the alpha beta superfamily
DY471_18920	COG1120	ATPase activity
DY471_18925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_18930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_18935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_18940	COG0708	Exodeoxyribonuclease III
DY471_18945	COG2169	Transcriptional regulator
DY471_18950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DY471_18955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DY471_18965	COG2364	Membrane
DY471_18985	COG0346	lactoylglutathione lyase activity
DY471_18990	COG3300	MHYT domain
DY471_18990	COG5001	Diguanylate cyclase
DY471_19010	COG1380	Effector of murein hydrolase LrgA
DY471_19015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DY471_19020	COG0596	Alpha beta hydrolase
DY471_19020	COG0508	dehydrogenase complex catalyzes the overall conversion of
DY471_19025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DY471_19045	COG1404	Belongs to the peptidase S8 family
DY471_19050	COG3773	Cell wall hydrolase
DY471_19065	COG1368	sulfuric ester hydrolase activity
DY471_19070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DY471_19080	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DY471_19125	COG4550	Control of competence regulator ComK, YlbF/YmcA
DY471_19135	COG1013	pyruvate-flavodoxin oxidoreductase activity
DY471_19140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DY471_19140	COG0674	pyruvate-flavodoxin oxidoreductase activity
DY471_19150	COG2359	stage V sporulation protein S
DY471_19180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DY471_19185	COG1426	Protein conserved in bacteria
DY471_19200	COG0300	oxidoreductase activity
DY471_19205	COG0612	Peptidase, M16
DY471_19210	COG0612	Peptidase, M16
DY471_19235	COG2188	Transcriptional regulator
DY471_19245	COG1674	ftsk spoiiie
DY471_19255	COG0740	serine-type endopeptidase activity
DY471_19260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DY471_19275	COG0527	aspartate kinase activity
DY471_19280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DY471_19285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DY471_19310	COG4824	toxin secretion phage lysis holin
DY471_19370	COG0740	serine-type endopeptidase activity
DY471_19410	COG0582	viral genome integration into host DNA
DY471_19445	COG0305	Participates in initiation and elongation during chromosome replication
DY471_19525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DY471_19530	COG1873	PFAM PRC-barrel domain
DY471_19535	COG0612	Peptidase, M16
DY471_19540	COG0726	polysaccharide deacetylase
DY471_19555	COG0196	riboflavin kinase activity
DY471_19570	COG1550	Protein conserved in bacteria
DY471_19580	COG1358	cellular component organization or biogenesis
DY471_19585	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DY471_19590	COG0195	Participates in both transcription termination and antitermination
DY471_19610	COG0750	zinc metalloprotease
DY471_19615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DY471_19620	COG4589	Belongs to the CDS family
DY471_19635	COG0528	UMP kinase activity
DY471_19665	COG4974	Belongs to the 'phage' integrase family
DY471_19675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DY471_19680	COG0758	DNA mediated transformation
DY471_19685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DY471_19725	COG1837	Belongs to the UPF0109 family
DY471_19735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DY471_19745	COG0552	protein localization to endoplasmic reticulum
DY471_19750	COG1196	nuclear chromosome segregation
DY471_19765	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_19770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DY471_19785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DY471_19790	COG1461	Dihydroxyacetone kinase
DY471_19795	COG1302	Protein conserved in bacteria
DY471_19810	COG1564	THIamine pyrophosphokinase
DY471_19815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DY471_19825	COG2815	serine threonine protein kinase
DY471_19825	COG0515	serine threonine protein kinase
DY471_19830	COG0631	protein serine/threonine phosphatase activity
DY471_19840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DY471_19840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DY471_19850	COG0242	peptide deformylase activity
DY471_19855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DY471_19860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DY471_19870	COG0194	GDP metabolic process
DY471_19880	COG1561	YicC-like family, N-terminal region
DY471_19885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DY471_19895	COG0006	proline dipeptidase activity
DY471_19915	COG3069	C4-dicarboxylate transmembrane transporter activity
DY471_19955	COG0505	Belongs to the CarA family
DY471_19980	COG0564	pseudouridine synthase activity
DY471_20000	COG3599	regulation of cell shape
DY471_20005	COG2302	S4 RNA-binding domain
DY471_20010	COG0762	integral membrane protein
DY471_20020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DY471_20030	COG1873	PFAM PRC-barrel domain
DY471_20035	COG1191	sigma factor activity
DY471_20040	COG1191	sigma factor activity
DY471_20050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DY471_20055	COG0849	cell division
DY471_20060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DY471_20070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DY471_20075	COG0772	Belongs to the SEDS family
DY471_20090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DY471_20095	COG0768	penicillin binding
DY471_20105	COG4839	cell division protein FtsL
DY471_20120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DY471_20140	COG1399	metal-binding, possibly nucleic acid-binding protein
DY471_20150	COG3480	Lon protease (S16) C-terminal proteolytic domain
DY471_20155	COG1752	Esterase of the alpha-beta hydrolase superfamily
DY471_20160	COG3314	Sporulation integral membrane protein YlbJ
DY471_20170	COG0742	ribosomal rna small subunit methyltransferase
DY471_20185	COG3679	Belongs to the UPF0342 family
DY471_20190	COG0406	alpha-ribazole phosphatase activity
DY471_20205	COG2340	Cysteine-rich secretory protein family
DY471_20220	COG3336	cytochrome c oxidase
DY471_20255	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DY471_20265	COG0772	Belongs to the SEDS family
DY471_20275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DY471_20280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DY471_20290	COG4896	Protein conserved in bacteria
DY471_20315	COG0483	inositol monophosphate 1-phosphatase activity
DY471_20335	COG1982	Orn Lys Arg decarboxylase major
DY471_20385	COG0022	dehydrogenase e1 component
DY471_20390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DY471_20400	COG0242	peptide deformylase activity
DY471_20405	COG0561	phosphatase activity
DY471_20420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DY471_20425	COG0569	domain protein
DY471_20445	COG0583	DNA-binding transcription factor activity
DY471_20450	COG0517	IMP dehydrogenase activity
DY471_20460	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DY471_20465	COG4703	Protein of unknown function (DUF1797)
DY471_20480	COG2200	EAL domain
DY471_20485	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_20490	COG1408	metallophosphoesterase
DY471_20505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DY471_20540	COG2814	Major facilitator Superfamily
DY471_20570	COG3209	COG3209 Rhs family protein
DY471_20580	COG2205	protein histidine kinase activity
DY471_20590	COG0436	Aminotransferase
DY471_20595	COG1609	Transcriptional regulator
DY471_20600	COG3833	ABC-type maltose transport systems, permease component
DY471_20605	COG1175	transmembrane transport
DY471_20610	COG2182	Extracellular solute-binding protein
DY471_20620	COG0366	Alpha amylase catalytic
DY471_20625	COG3842	ATPase activity
DY471_20665	COG0183	Belongs to the thiolase family
DY471_20700	COG1695	Transcriptional regulator
DY471_20705	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_20725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DY471_20730	COG0436	Aminotransferase
DY471_20765	COG2084	Dehydrogenase
DY471_20770	COG3706	GGDEF domain
DY471_20775	COG0778	Nitroreductase
DY471_20800	COG2190	(PTS) system
DY471_20800	COG1263	PTS System
DY471_20800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DY471_20805	COG3711	transcriptional antiterminator
DY471_20825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DY471_20855	COG1547	Domain of unknown function (DUF309)
DY471_20860	COG0456	acetyltransferase
DY471_20870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DY471_20875	COG4086	secreted protein
DY471_20880	COG0561	phosphatase activity
DY471_20885	COG0697	spore germination
DY471_20900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_20925	COG0733	neurotransmitter:sodium symporter activity
DY471_20945	COG1686	Belongs to the peptidase S11 family
DY471_20955	COG1725	Transcriptional regulator
DY471_20960	COG1131	(ABC) transporter
DY471_20975	COG1846	Transcriptional regulator
DY471_20990	COG0598	Magnesium transport protein CorA
DY471_21015	COG4974	Belongs to the 'phage' integrase family
DY471_21025	COG0735	belongs to the Fur family
DY471_21030	COG1300	Membrane
DY471_21050	COG0667	Aldo Keto reductase
DY471_21055	COG0656	L-ascorbic acid biosynthetic process
DY471_21060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DY471_21060	COG0456	acetyltransferase
DY471_21070	COG4085	toxin activity
DY471_21070	COG0737	Belongs to the 5'-nucleotidase family
DY471_21070	COG1525	nuclease
DY471_21080	COG0596	Alpha beta hydrolase
DY471_21085	COG2056	Na+-H+ antiporter family
DY471_21090	COG1609	Transcriptional regulator
DY471_21095	COG0456	acetyltransferase
DY471_21100	COG1073	alpha beta
DY471_21115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DY471_21115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DY471_21120	COG0307	riboflavin synthase, alpha
DY471_21140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DY471_21145	COG4106	trans-aconitate 2-methyltransferase activity
DY471_21150	COG2226	methyltransferase
DY471_21150	COG1073	alpha beta
DY471_21165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DY471_21180	COG0737	Belongs to the 5'-nucleotidase family
DY471_21190	COG1522	sequence-specific DNA binding
DY471_21210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DY471_21235	COG0300	oxidoreductase activity
DY471_21240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_21245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DY471_21250	COG1760	l-serine dehydratase
DY471_21255	COG1760	l-serine dehydratase
DY471_21290	COG2195	Cleaves the N-terminal amino acid of tripeptides
DY471_21295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_21305	COG1376	ErfK ybiS ycfS ynhG family protein
DY471_21310	COG4129	membrane
DY471_21315	COG1126	abc transporter atp-binding protein
DY471_21320	COG0765	amino acid transport
DY471_21325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DY471_21350	COG2323	membrane
DY471_21355	COG0772	Belongs to the SEDS family
DY471_21360	COG0508	dehydrogenase complex catalyzes the overall conversion of
DY471_21365	COG0022	dehydrogenase e1 component
DY471_21370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DY471_21375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DY471_21385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DY471_21390	COG0280	phosphate acetyltransferase
DY471_21400	COG3829	transcription factor binding
DY471_21400	COG3290	protein histidine kinase activity
DY471_21410	COG0584	glycerophosphoryl diester phosphodiesterase
DY471_21415	COG3093	addiction module antidote protein HigA
DY471_21425	COG0745	RESPONSE REGULATOR receiver
DY471_21435	COG0750	zinc metalloprotease
DY471_21440	COG0497	DNA recombination
DY471_21450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DY471_21460	COG0142	geranyltranstransferase activity
DY471_21485	COG1302	Protein conserved in bacteria
DY471_21490	COG0439	Biotin carboxylase
DY471_21495	COG0511	ligase activity, forming carbon-carbon bonds
DY471_21540	COG3854	ATPases associated with a variety of cellular activities
DY471_21565	COG0006	proline dipeptidase activity
DY471_21580	COG3872	metal-dependent enzyme
DY471_21590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DY471_21625	COG0095	Lipoate-protein ligase
DY471_21630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DY471_21635	COG1609	Transcriptional regulator
DY471_21645	COG2076	Multidrug Resistance protein
DY471_21650	COG2076	Multidrug Resistance protein
DY471_21685	COG1131	(ABC) transporter
DY471_21690	COG1725	Transcriptional regulator
DY471_21725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DY471_21780	COG4970	Tfp pilus assembly protein FimT
DY471_21790	COG1459	type II secretion system
DY471_21795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DY471_21845	COG1410	methionine synthase
DY471_21845	COG0646	methionine synthase
DY471_21850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DY471_21850	COG0646	methionine synthase
DY471_21855	COG0626	cystathionine gamma-synthase activity
DY471_21860	COG0626	cystathionine gamma-synthase activity
DY471_21880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_21890	COG1940	carbohydrate kinase activity
DY471_21895	COG4483	Protein conserved in bacteria
DY471_21900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DY471_21910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DY471_21915	COG0704	Plays a role in the regulation of phosphate uptake
DY471_21920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DY471_21925	COG0581	inorganic phosphate transmembrane transporter activity
DY471_21930	COG0573	inorganic phosphate transmembrane transporter activity
DY471_21935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DY471_21945	COG0477	Major facilitator Superfamily
DY471_21950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DY471_21975	COG0735	belongs to the Fur family
DY471_21980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DY471_21985	COG1121	(ABC) transporter
DY471_21990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_22020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DY471_22025	COG2384	SAM-dependent methyltransferase
DY471_22030	COG2010	Cytochrome c
DY471_22035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DY471_22040	COG0358	DNA primase activity
DY471_22050	COG0517	IMP dehydrogenase activity
DY471_22065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DY471_22070	COG0295	cytidine deaminase activity
DY471_22075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DY471_22085	COG1480	7TM receptor with intracellular HD hydrolase
DY471_22090	COG1702	phosphate starvation-inducible protein PhoH
DY471_22105	COG1610	YqeY-like protein
DY471_22120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DY471_22125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DY471_22145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DY471_22155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DY471_22160	COG1733	regulation of RNA biosynthetic process
DY471_22185	COG1466	dna polymerase III delta subunit
DY471_22195	COG0658	competence protein
DY471_22195	COG2333	competence protein COMEC
DY471_22200	COG2131	deaminase
DY471_22205	COG1596	polysaccharide export
DY471_22205	COG1555	photosystem II stabilization
DY471_22210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DY471_22215	COG2226	methyltransferase
DY471_22220	COG0799	negative regulation of ribosome biogenesis
DY471_22225	COG1713	HD superfamily hydrolase involved in NAD metabolism
DY471_22235	COG1534	Rna-binding protein
DY471_22245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DY471_22250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DY471_22265	COG1191	sigma factor activity
DY471_22285	COG0778	Nitroreductase
DY471_22290	COG2357	RelA SpoT domain protein
DY471_22300	COG1785	Belongs to the alkaline phosphatase family
DY471_22310	COG2267	carboxylic ester hydrolase activity
DY471_22345	COG1404	Belongs to the peptidase S8 family
DY471_22350	COG3186	Phenylalanine-4-hydroxylase
DY471_22360	COG2514	catechol 2,3-dioxygenase activity
DY471_22365	COG2259	Doxx family
DY471_22405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DY471_22415	COG1012	belongs to the aldehyde dehydrogenase family
DY471_22415	COG1454	alcohol dehydrogenase
DY471_22420	COG0626	cystathionine gamma-synthase activity
DY471_22425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DY471_22450	COG0768	penicillin binding
DY471_22485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DY471_22515	COG0628	permease
DY471_22535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DY471_22550	COG1104	cysteine desulfurase activity
DY471_22555	COG1959	2 iron, 2 sulfur cluster binding
DY471_22560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DY471_22575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DY471_22585	COG0124	histidyl-tRNA synthetase
DY471_22600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DY471_22610	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DY471_22610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DY471_22615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DY471_22620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DY471_22620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DY471_22630	COG2244	polysaccharide biosynthetic process
DY471_22635	COG2323	membrane
DY471_22645	COG1862	Preprotein translocase
DY471_22675	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DY471_22685	COG0697	spore germination
DY471_22690	COG0640	Transcriptional regulator
DY471_22715	COG0157	Belongs to the NadC ModD family
DY471_22720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DY471_22725	COG1104	cysteine desulfurase activity
DY471_22730	COG1827	regulation of RNA biosynthetic process
DY471_22735	COG2258	MOSC domain
DY471_22740	COG0077	Prephenate dehydratase
DY471_22745	COG0577	efflux transmembrane transporter activity
DY471_22750	COG0577	efflux transmembrane transporter activity
DY471_22755	COG1136	(ABC) transporter
DY471_22760	COG5002	protein histidine kinase activity
DY471_22765	COG0745	RESPONSE REGULATOR receiver
DY471_22775	COG3290	protein histidine kinase activity
DY471_22785	COG2868	ribosomal protein
DY471_22795	COG1530	ribonuclease E activity
DY471_22800	COG1994	Peptidase M50
DY471_22805	COG0739	heme binding
DY471_22810	COG2894	cell division
DY471_22825	COG1792	Involved in formation and maintenance of cell shape
DY471_22830	COG1077	Cell shape determining protein MreB Mrl
DY471_22855	COG0285	dihydrofolate synthase activity
DY471_22860	COG0525	valine-tRNA ligase activity
DY471_22870	COG1388	LysM domain
DY471_22880	COG0113	porphobilinogen synthase activity
DY471_22885	COG1587	Uroporphyrinogen-III synthase
DY471_22895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DY471_22905	COG1846	Transcriptional regulator
DY471_22910	COG1764	response to oxidative stress
DY471_22925	COG1067	ATP-dependent peptidase activity
DY471_22925	COG0470	DNA polymerase III
DY471_22970	COG0622	Phosphoesterase
DY471_22975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DY471_22985	COG5401	PFAM Sporulation and spore germination
DY471_23005	COG1309	transcriptional regulator
DY471_23020	COG2197	response regulator
DY471_23025	COG2233	PERMEase
DY471_23030	COG0402	S-adenosylhomocysteine deaminase activity
DY471_23040	COG1396	sequence-specific DNA binding
DY471_23045	COG0697	spore germination
DY471_23055	COG1959	2 iron, 2 sulfur cluster binding
DY471_23060	COG1668	transmembrane transport
DY471_23070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DY471_23075	COG1360	Flagellar Motor Protein
DY471_23080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DY471_23085	COG1876	peptidase activity
DY471_23090	COG0824	Thioesterase
DY471_23095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DY471_23100	COG1053	succinate dehydrogenase
DY471_23105	COG2009	succinate dehydrogenase
DY471_23110	COG1719	4-vinyl reductase, 4VR
DY471_23120	COG3118	belongs to the thioredoxin family
DY471_23125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DY471_23130	COG2086	electron transfer activity
DY471_23135	COG1024	Enoyl-CoA hydratase
DY471_23140	COG1309	transcriptional regulator
DY471_23145	COG0318	PFAM AMP-dependent synthetase and ligase
DY471_23155	COG2318	DinB family
DY471_23175	COG1131	(ABC) transporter
DY471_23180	COG2205	protein histidine kinase activity
DY471_23185	COG0745	RESPONSE REGULATOR receiver
DY471_23190	COG4895	conserved protein (DUF2196)
DY471_23195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DY471_23210	COG4509	Sortase family
DY471_23215	COG1120	ATPase activity
DY471_23230	COG5386	Cell surface protein
DY471_23235	COG5386	Cell surface protein
DY471_23240	COG1114	Component of the transport system for branched-chain amino acids
DY471_23245	COG1187	pseudouridine synthase activity
DY471_23255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DY471_23255	COG1796	DNA polymerase
DY471_23260	COG1286	toxin biosynthetic process
DY471_23290	COG0017	Asparaginyl-tRNA synthetase
DY471_23295	COG0072	phenylalanine-tRNA ligase activity
DY471_23295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DY471_23305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DY471_23315	COG1418	mRNA catabolic process
DY471_23325	COG2814	Major facilitator Superfamily
DY471_23330	COG1566	PFAM secretion protein HlyD family protein
DY471_23335	COG1309	transcriptional regulator
DY471_23340	COG1363	Peptidase, m42
DY471_23360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DY471_23365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DY471_23375	COG1484	DNA-dependent DNA replication
DY471_23380	COG3611	Membrane attachment protein
DY471_23390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DY471_23395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DY471_23400	COG0237	dephospho-CoA kinase activity
DY471_23405	COG1971	Probably functions as a manganese efflux pump
DY471_23410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DY471_23415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DY471_23415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DY471_23420	COG5002	protein histidine kinase activity
DY471_23425	COG0745	RESPONSE REGULATOR receiver
DY471_23440	COG0538	isocitrate dehydrogenase activity
DY471_23445	COG0372	Belongs to the citrate synthase family
DY471_23460	COG0628	permease
DY471_23465	COG3030	protein affecting phage T7 exclusion by the F plasmid
DY471_23490	COG1725	Transcriptional regulator
DY471_23495	COG0281	malic enzyme
DY471_23500	COG0587	DNA-directed DNA polymerase activity
DY471_23515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DY471_23540	COG4109	DRTGG domain
DY471_23550	COG0006	proline dipeptidase activity
DY471_23595	COG0662	Cupin 2, conserved barrel domain protein
DY471_23605	COG1476	TRANSCRIPTIONal
DY471_23620	COG1028	Short-chain dehydrogenase reductase Sdr
DY471_23625	COG0589	response to stress
DY471_23685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_23705	COG0827	DNA restriction-modification system
DY471_23710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DY471_23715	COG3874	Sporulation protein YtfJ
DY471_23725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DY471_23730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DY471_23740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DY471_23755	COG1104	cysteine desulfurase activity
DY471_23765	COG0583	DNA-binding transcription factor activity
DY471_23770	COG0697	spore germination
DY471_23775	COG1309	transcriptional regulator
DY471_23780	COG1956	GAF domain-containing protein
DY471_23785	COG0626	cystathionine gamma-synthase activity
DY471_23805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DY471_23815	COG1595	DNA-templated transcription, initiation
DY471_23830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DY471_23835	COG0454	-acetyltransferase
DY471_23840	COG0517	IMP dehydrogenase activity
DY471_23845	COG0123	including yeast histone deacetylase and acetoin utilization protein
DY471_23850	COG2267	carboxylic ester hydrolase activity
DY471_23855	COG0745	RESPONSE REGULATOR receiver
DY471_23860	COG5002	protein histidine kinase activity
DY471_23865	COG0666	response to abiotic stimulus
DY471_23900	COG1609	Transcriptional regulator
DY471_23915	COG4851	CamS sex pheromone cAM373 precursor
DY471_23920	COG3118	belongs to the thioredoxin family
DY471_23930	COG2309	aminopeptidase activity
DY471_23950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_23975	COG1674	ftsk spoiiie
DY471_23985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DY471_23995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DY471_24000	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DY471_24005	COG1363	Peptidase, m42
DY471_24015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_24030	COG0510	thiamine kinase activity
DY471_24035	COG1523	belongs to the glycosyl hydrolase 13 family
DY471_24045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DY471_24050	COG1349	DNA-binding transcription factor activity
DY471_24055	COG1187	pseudouridine synthase activity
DY471_24060	COG2244	polysaccharide biosynthetic process
DY471_24065	COG2081	HI0933 family
DY471_24070	COG2814	Major facilitator Superfamily
DY471_24080	COG3832	glyoxalase III activity
DY471_24105	COG1329	Transcriptional regulator
DY471_24130	COG0314	molybdopterin synthase activity
DY471_24135	COG1763	Mo-molybdopterin cofactor biosynthetic process
DY471_24140	COG0303	'Molybdopterin
DY471_24150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DY471_24155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DY471_24175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DY471_24185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DY471_24225	COG2814	Major facilitator Superfamily
DY471_24230	COG0475	glutathione-regulated potassium exporter activity
DY471_24235	COG0490	domain, Protein
DY471_24240	COG0582	viral genome integration into host DNA
DY471_24250	COG1136	(ABC) transporter
DY471_24270	COG1242	4 iron, 4 sulfur cluster binding
DY471_24275	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DY471_24290	COG1794	racemase activity, acting on amino acids and derivatives
DY471_24315	COG2267	carboxylic ester hydrolase activity
DY471_24320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DY471_24325	COG0671	phosphoesterase, PA-phosphatase related
DY471_24330	COG0438	transferase activity, transferring glycosyl groups
DY471_24340	COG0521	Mo-molybdopterin cofactor biosynthetic process
DY471_24350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_24390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DY471_24395	COG5002	protein histidine kinase activity
DY471_24400	COG4191	Histidine kinase
DY471_24405	COG2267	carboxylic ester hydrolase activity
DY471_24410	COG1368	sulfuric ester hydrolase activity
DY471_24425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DY471_24430	COG1116	anion transmembrane transporter activity
DY471_24435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DY471_24455	COG0494	nUDIX hydrolase
DY471_24485	COG0288	reversible hydration of carbon dioxide
DY471_24490	COG1271	oxidase subunit
DY471_24495	COG1294	oxidase, subunit
DY471_24515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_24540	COG1842	Phage shock protein A
DY471_24590	COG5002	protein histidine kinase activity
DY471_24595	COG0745	RESPONSE REGULATOR receiver
DY471_24625	COG1597	lipid kinase activity
DY471_24640	COG0577	efflux transmembrane transporter activity
DY471_24645	COG1136	(ABC) transporter
DY471_24670	COG0586	Pfam SNARE associated Golgi protein
DY471_24690	COG0577	efflux transmembrane transporter activity
DY471_24695	COG1136	(ABC) transporter
DY471_24700	COG2207	Transcriptional regulator
DY471_24700	COG3708	Transcriptional regulator
DY471_24710	COG1131	(ABC) transporter
DY471_24715	COG5658	integral membrane protein
DY471_24720	COG0640	Transcriptional regulator
DY471_24725	COG0745	RESPONSE REGULATOR receiver
DY471_24730	COG2205	protein histidine kinase activity
DY471_24735	COG0577	efflux transmembrane transporter activity
DY471_24740	COG0577	efflux transmembrane transporter activity
DY471_24745	COG1136	(ABC) transporter
DY471_24750	COG0577	efflux transmembrane transporter activity
DY471_24785	COG3964	amidohydrolase
DY471_24810	COG4948	Mandelate Racemase Muconate Lactonizing
DY471_24820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DY471_24825	COG0596	Alpha beta hydrolase
DY471_24835	COG1169	isochorismate synthase
DY471_24840	COG1575	Belongs to the MenA family. Type 1 subfamily
DY471_24845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DY471_24850	COG1278	Cold shock
DY471_24865	COG0058	SHG alpha-glucan phosphorylase activity
DY471_24875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DY471_24880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DY471_24905	COG0039	L-malate dehydrogenase activity
DY471_24915	COG1595	DNA-templated transcription, initiation
DY471_25010	COG0544	peptidyl-prolyl cis-trans isomerase activity
DY471_25045	COG1285	pathogenesis
DY471_25050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DY471_25070	COG2155	Conserved Protein
DY471_25075	COG1098	S1 RNA binding domain
DY471_25080	COG0436	Aminotransferase
DY471_25085	COG1522	sequence-specific DNA binding
DY471_25090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DY471_25095	COG2267	carboxylic ester hydrolase activity
DY471_25105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DY471_25120	COG5018	Exonuclease
DY471_25125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DY471_25140	COG0423	glycine-tRNA ligase activity
DY471_25145	COG2050	protein possibly involved in aromatic compounds catabolism
DY471_25155	COG1268	BioY protein
DY471_25165	COG0297	glycogen (starch) synthase activity
DY471_25185	COG4485	Bacterial membrane protein, YfhO
DY471_25190	COG2246	polysaccharide biosynthetic process
DY471_25195	COG0463	Glycosyl transferase, family 2
DY471_25200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DY471_25205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DY471_25225	COG3584	3D domain protein
DY471_25240	COG1252	NADH dehydrogenase
DY471_25255	COG3708	Transcriptional regulator
DY471_25270	COG1683	Conserved Protein
DY471_25280	COG0316	Belongs to the HesB IscA family
DY471_25295	COG1252	NADH dehydrogenase
DY471_25310	COG0390	transport system, permease component
DY471_25345	COG2824	Alkylphosphonate utilization operon protein PhnA
DY471_25365	COG4837	Protein of unknown function (DUF1462)
DY471_25370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DY471_25380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DY471_25385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DY471_25400	COG1136	(ABC) transporter
DY471_25400	COG0577	efflux transmembrane transporter activity
DY471_25405	COG2249	NAD(P)H dehydrogenase (quinone) activity
DY471_25415	COG0647	UMP catabolic process
DY471_25425	COG2445	Protein of unknown function DUF86
DY471_25430	COG1494	fructose-1,6-bisphosphatase
DY471_25445	COG4470	Protein conserved in bacteria
DY471_25455	COG0789	Transcriptional regulator
DY471_25460	COG4377	Putative membrane peptidase family (DUF2324)
DY471_25485	COG0739	heme binding
DY471_25495	COG3377	Domain of unknown function (DUF1805)
DY471_25500	COG0737	Belongs to the 5'-nucleotidase family
DY471_25510	COG0719	Fe-S assembly protein
DY471_25515	COG0822	iron-sulfur transferase activity
DY471_25520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DY471_25525	COG0719	Fe-S assembly protein
DY471_25530	COG0396	ATPase activity
DY471_25535	COG1464	Belongs to the NlpA lipoprotein family
DY471_25540	COG1464	Belongs to the NlpA lipoprotein family
DY471_25545	COG2011	ABC-type metal ion transport system permease component
DY471_25560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DY471_25565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DY471_25575	COG1393	Belongs to the ArsC family
DY471_25625	COG1309	transcriptional regulator
DY471_25630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DY471_25635	COG1960	acyl-CoA dehydrogenase activity
DY471_25640	COG0183	Belongs to the thiolase family
DY471_25645	COG1024	Enoyl-CoA hydratase
DY471_25645	COG1250	3-hydroxyacyl-CoA dehydrogenase
DY471_25655	COG1686	Belongs to the peptidase S11 family
DY471_25670	COG0011	TIGRFAM Protein of
DY471_25675	COG0840	transmembrane signaling receptor activity
DY471_25690	COG2814	Major facilitator Superfamily
DY471_25695	COG0531	amino acid
DY471_25710	COG0706	membrane insertase activity
DY471_25720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DY471_25760	COG0586	Pfam SNARE associated Golgi protein
DY471_25770	COG1376	ErfK ybiS ycfS ynhG family protein
DY471_25775	COG0745	RESPONSE REGULATOR receiver
DY471_25780	COG5002	protein histidine kinase activity
DY471_25805	COG0840	transmembrane signaling receptor activity
DY471_25810	COG2151	metal-sulfur cluster biosynthetic enzyme
DY471_25815	COG3227	Zinc metalloprotease (Elastase)
DY471_25820	COG1741	Belongs to the pirin family
DY471_25835	COG0475	glutathione-regulated potassium exporter activity
DY471_25840	COG0490	domain, Protein
DY471_25845	COG1115	amino acid carrier protein
DY471_25850	COG0783	Belongs to the Dps family
DY471_25870	COG1611	Belongs to the LOG family
DY471_25885	COG2311	Membrane
DY471_25890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_25895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_25900	COG1115	amino acid carrier protein
DY471_25905	COG1115	amino acid carrier protein
DY471_25910	COG2910	NAD(P)H-binding
DY471_25925	COG0656	L-ascorbic acid biosynthetic process
DY471_25930	COG2814	Major facilitator Superfamily
DY471_25935	COG1733	regulation of RNA biosynthetic process
DY471_25945	COG1252	NADH dehydrogenase
DY471_25950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DY471_25965	COG0840	transmembrane signaling receptor activity
DY471_25965	COG3290	protein histidine kinase activity
DY471_25975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DY471_25995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DY471_26000	COG3223	Belongs to the PsiE family
DY471_26040	COG5002	protein histidine kinase activity
DY471_26045	COG0745	RESPONSE REGULATOR receiver
DY471_26050	COG1136	(ABC) transporter
DY471_26070	COG1136	(ABC) transporter
DY471_26100	COG0557	exoribonuclease II activity
DY471_26105	COG1647	Serine aminopeptidase, S33
DY471_26110	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DY471_26115	COG1346	cytolysis
DY471_26150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DY471_26165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DY471_26190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DY471_26205	COG2323	membrane
DY471_26225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DY471_26235	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DY471_26245	COG1051	belongs to the nudix hydrolase family
DY471_26255	COG0492	ferredoxin-NADP+ reductase activity
DY471_26260	COG0457	Tetratricopeptide repeat
DY471_26265	COG0110	maltose O-acetyltransferase activity
DY471_26285	COG1950	PFAM Membrane protein of
DY471_26295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DY471_26315	COG0789	Transcriptional regulator
DY471_26350	COG0583	DNA-binding transcription factor activity
DY471_26360	COG0655	NAD(P)H dehydrogenase (quinone) activity
DY471_26365	COG0488	(ABC) transporter
DY471_26375	COG1132	(ABC) transporter
DY471_26380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DY471_26385	COG3409	Peptidoglycan-binding domain 1 protein
DY471_26385	COG0793	Belongs to the peptidase S41A family
DY471_26390	COG2177	Part of the ABC transporter FtsEX involved in
DY471_26395	COG2884	Cell division ATP-binding protein ftsE
DY471_26415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DY471_26420	COG1278	Cold shock
DY471_26425	COG1040	competence protein
DY471_26430	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DY471_26435	COG1388	LysM domain
DY471_26435	COG0791	NLP P60 protein
DY471_26440	COG1733	regulation of RNA biosynthetic process
DY471_26445	COG1307	EDD domain protein, DegV family
DY471_26450	COG1739	Uncharacterized protein family UPF0029
DY471_26455	COG1316	TRANSCRIPTIONal
DY471_26460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DY471_26465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DY471_26470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DY471_26480	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DY471_26480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DY471_26500	COG1486	melibiose metabolic process
DY471_26505	COG1447	Phosphotransferase system cellobiose-specific component IIA
DY471_26510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DY471_26520	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DY471_26530	COG1447	Phosphotransferase system cellobiose-specific component IIA
DY471_26540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DY471_26545	COG1301	dicarboxylic acid transport
DY471_26555	COG0346	lactoylglutathione lyase activity
DY471_26560	COG1511	domain protein
DY471_26565	COG0583	DNA-binding transcription factor activity
DY471_26570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DY471_26575	COG1271	oxidase subunit
DY471_26580	COG1294	oxidase, subunit
DY471_26585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DY471_26595	COG1620	l-lactate permease
DY471_26605	COG2389	metal-binding protein
DY471_26620	COG1368	sulfuric ester hydrolase activity
DY471_26630	COG0791	NLP P60 protein
DY471_26630	COG1388	LysM domain
DY471_26635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DY471_26645	COG1215	transferase activity, transferring glycosyl groups
DY471_26650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DY471_26660	COG1388	LysM domain
DY471_26660	COG3584	3D domain protein
DY471_26670	COG4715	Zinc finger, swim domain protein
DY471_26675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DY471_26705	COG1191	sigma factor activity
DY471_26715	COG0577	efflux transmembrane transporter activity
DY471_26720	COG1136	(ABC) transporter
DY471_26755	COG5002	protein histidine kinase activity
DY471_26760	COG0745	RESPONSE REGULATOR receiver
DY471_26765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DY471_26790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DY471_26795	COG1134	teichoic acid transport
DY471_26800	COG1682	transport, permease protein
DY471_26805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DY471_26815	COG0438	transferase activity, transferring glycosyl groups
DY471_26820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DY471_26825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DY471_26830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DY471_26840	COG1609	Transcriptional regulator
DY471_26850	COG0739	heme binding
DY471_26865	COG3279	Response regulator of the LytR AlgR family
DY471_26870	COG2385	sporulation resulting in formation of a cellular spore
DY471_26875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DY471_26885	COG4836	Membrane
DY471_26890	COG1007	ATP synthesis coupled electron transport
DY471_26895	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DY471_26900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DY471_26910	COG0839	Belongs to the complex I subunit 6 family
DY471_26930	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DY471_26940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DY471_26945	COG5001	Diguanylate cyclase
DY471_26945	COG3300	MHYT domain
DY471_26995	COG0356	it plays a direct role in the translocation of protons across the membrane
DY471_27030	COG0698	ribose 5-phosphate isomerase
DY471_27040	COG2190	(PTS) system
DY471_27045	COG2259	Doxx family
DY471_27050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DY471_27065	COG0009	L-threonylcarbamoyladenylate synthase
DY471_27080	COG2890	protein-(glutamine-N5) methyltransferase activity
DY471_27085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DY471_27105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DY471_27110	COG1494	fructose-1,6-bisphosphatase
DY471_27115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DY471_27130	COG4821	SIS domain
DY471_27150	COG1960	acyl-CoA dehydrogenase activity
DY471_27155	COG1960	acyl-CoA dehydrogenase activity
DY471_27160	COG1250	3-hydroxyacyl-CoA dehydrogenase
DY471_27165	COG0183	Belongs to the thiolase family
DY471_27170	COG0247	lactate metabolic process
DY471_27170	COG2181	nitrate reductase activity
DY471_27175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DY471_27185	COG5001	Diguanylate cyclase
DY471_27185	COG3300	MHYT domain
DY471_27205	COG2197	response regulator
DY471_27210	COG4585	Histidine kinase
DY471_27215	COG0842	Transport permease protein
DY471_27220	COG1131	(ABC) transporter
DY471_27225	COG0024	Methionine aminopeptidase
DY471_27235	COG2234	aminopeptidase activity
DY471_27255	COG1595	DNA-templated transcription, initiation
DY471_27265	COG4506	Protein conserved in bacteria
DY471_27270	COG1619	proteins homologs of microcin C7 resistance protein MccF
DY471_27290	COG0010	Belongs to the arginase family
DY471_27295	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DY471_27300	COG2814	Major facilitator Superfamily
DY471_27305	COG0789	Transcriptional regulator
DY471_27310	COG0584	glycerophosphoryl diester phosphodiesterase
DY471_27315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DY471_27325	COG1994	Peptidase M50
DY471_27335	COG1078	dGTPase activity
DY471_27340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DY471_27345	COG1120	ATPase activity
DY471_27350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_27355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DY471_27375	COG0095	Lipoate-protein ligase
DY471_27380	COG0280	phosphate acetyltransferase
DY471_27395	COG3773	Cell wall hydrolase
DY471_27405	COG2363	Small membrane protein
DY471_27415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DY471_27420	COG2233	PERMEase
DY471_27425	COG0561	phosphatase activity
DY471_27430	COG2814	Major facilitator Superfamily
DY471_27440	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DY471_27445	COG1131	(ABC) transporter
DY471_27450	COG2755	lipolytic protein G-D-S-L family
DY471_27455	COG1609	Transcriptional regulator
DY471_27465	COG0460	homoserine dehydrogenase
DY471_27485	COG1011	Hydrolase
DY471_27490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DY471_27500	COG2197	response regulator
DY471_27505	COG4585	Histidine kinase
DY471_27505	COG2203	Gaf domain
DY471_27510	COG0351	phosphomethylpyrimidine kinase
DY471_27515	COG3706	GGDEF domain
DY471_27520	COG2879	small protein
DY471_27525	COG1966	Carbon starvation protein
DY471_27530	COG3279	Response regulator of the LytR AlgR family
DY471_27535	COG0477	Major facilitator Superfamily
DY471_27560	COG0840	transmembrane signaling receptor activity
DY471_27570	COG1607	acyl-coa hydrolase
DY471_27585	COG0488	(ABC) transporter
DY471_27595	COG1309	transcriptional regulator
DY471_27600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DY471_27605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DY471_27605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DY471_27610	COG0628	permease
DY471_27625	COG3279	Response regulator of the LytR AlgR family
DY471_27630	COG3275	phosphorelay sensor kinase activity
DY471_27635	COG2814	Major facilitator Superfamily
DY471_27640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DY471_27645	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DY471_27655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DY471_27675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DY471_27680	COG1272	protein, Hemolysin III
DY471_27700	COG1164	Oligoendopeptidase f
DY471_27720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DY471_27725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DY471_27730	COG4853	Protein conserved in bacteria
DY471_27735	COG4863	YycH protein
DY471_27740	COG5002	protein histidine kinase activity
DY471_27745	COG0745	RESPONSE REGULATOR receiver
DY471_27775	COG0305	Participates in initiation and elongation during chromosome replication
DY471_27785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DY471_27790	COG4241	membrane
DY471_27800	COG0629	single-stranded DNA binding
DY471_27810	COG0012	GTP binding
DY471_27815	COG4481	Protein conserved in bacteria
DY471_27820	COG0668	transmembrane transport
DY471_27830	COG1475	DNA binding
DY471_27835	COG1192	Involved in chromosome partitioning
DY471_27860	COG1847	R3H domain protein
DY471_27865	COG0706	membrane insertase activity
DY471_27895	COG5484	DNA packaging
DY471_27985	COG4824	toxin secretion phage lysis holin
DY471_28015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DY471_28060	COG3409	Peptidoglycan-binding domain 1 protein
DY471_28060	COG5632	N-Acetylmuramoyl-L-alanine amidase
DY471_28105	COG1192	Involved in chromosome partitioning
DY471_28135	COG2274	protein secretion by the type I secretion system
DY471_28145	COG0789	Transcriptional regulator
DY471_28215	COG1396	sequence-specific DNA binding
DY471_28225	COG3617	BRO family, N-terminal domain
DY471_28245	COG1484	DNA-dependent DNA replication