locus-tag class description BG02_1002 ENOG4105CB5 ATP-dependent DNA helicase recG BG02_1003 ENOG4105DP4 dak2 domain fusion protein ylov BG02_1004 ENOG4108ZAA Alkaline-shock protein BG02_1006 ENOG4105FJ0 thiamine BG02_1007 ENOG4105DJV ribulose-phosphate 3-epimerase BG02_1008 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BG02_1009 ENOG4105D9P serine threonine protein kinase BG02_101 ENOG4105C8Y Acetylornithine aminotransferase BG02_1010 ENOG4108ZF3 Phosphatase BG02_1012 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BG02_1014 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BG02_1015 ENOG4105C25 Primosomal protein n' BG02_1016 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BG02_1020 ENOG4105DSJ YicC domain protein BG02_1022 ENOG4105F23 Fibronectin-binding protein BG02_1023 ENOG4105DC7 peptidase M24 BG02_1034 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BG02_1039 ENOG4105C34 Pseudouridine synthase BG02_1042 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BG02_1044 ENOG4105DBK s4 domain protein BG02_1045 ENOG41067XK integral membrane protein BG02_1047 ENOG4105DFA alanine racemase domain protein BG02_1048 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BG02_1049 ENOG4105WR5 sporulation protein, YlmC YmxH family BG02_1051 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_1053 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BG02_1054 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BG02_1055 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BG02_1056 ENOG4105D4A Cell wall formation (By similarity) BG02_1057 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BG02_1058 ENOG4105CNI cell division protein FtsW BG02_1061 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG02_1062 ENOG4105CJN penicillin-binding protein BG02_1063 ENOG4105CJN penicillin-binding protein BG02_1064 ENOG41068DC Essential cell division protein (By similarity) BG02_1071 ENOG4105KNH Nucleic acid-binding protein BG02_1081 ENOG4105XSJ toxin secretion phage lysis holin BG02_1098 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BG02_110 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG02_1100 ENOG4105CAR Terminase, large subunit BG02_1117 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BG02_112 ENOG4108TVJ Nitroreductase BG02_1120 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_113 ENOG4105FS7 Transcriptional regulator BG02_1131 ENOG4108IMY Transcriptional regulator BG02_1139 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BG02_1141 ENOG41063PX domain protein BG02_1142 ENOG4105D78 K07001 NTE family protein BG02_1144 ENOG4105H20 Sporulation integral membrane protein YlbJ BG02_1145 ENOG4106H78 methyltransferase BG02_1150 ENOG4107TB6 phosphoglycerate mutase BG02_1153 ENOG4106UY4 Inherit from COG: Scp-like extracellular BG02_1163 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BG02_1164 ENOG4105CNI cell division protein FtsW BG02_1167 ENOG4108IAB Phoh family BG02_1171 ENOG4105QA2 BG02_1172 ENOG4105CI3 gtp-binding protein typa BG02_1174 ENOG4105ECY inositol monophosphatase BG02_1178 ENOG4105CXN decarboxylase BG02_1187 ENOG4105C7S Dehydrogenase BG02_1188 ENOG4105CPP Dehydrogenase, E1 component BG02_1191 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BG02_1192 ENOG4108X4Q Hydrolase BG02_1194 ENOG4105CN5 Metallo-Beta-Lactamase BG02_1195 ENOG4107ZYR domain protein BG02_120 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG02_1202 ENOG4108XRC Protein of unknown function (DUF458) BG02_1204 ENOG4107IN1 Protein of unknown function (DUF1797) BG02_1207 ENOG4105EPM Diguanylate phosphodiesterase BG02_1208 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BG02_1211 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BG02_1213 ENOG4105UIN BG02_122 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BG02_1224 ENOG4108HGU Histidine kinase BG02_1226 ENOG4105CHM Aminotransferase BG02_1227 ENOG4105FKQ transcriptional regulator BG02_1228 ENOG4105EG2 ABC transporter, permease BG02_1230 ENOG4107FKK extracellular solute-binding protein family 1 BG02_1232 ENOG4105CG3 alpha amylase, catalytic region BG02_1241 ENOG4105CHU acetyl-coa acetyltransferase BG02_1248 ENOG4105K7K Transcriptional regulator BG02_1249 ENOG4105DTD Dehydrogenase BG02_1251 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BG02_1253 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BG02_1258 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BG02_1261 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG02_1262 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG02_1263 ENOG4106TD9 Diguanylate cyclase BG02_1267 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BG02_1270 ENOG4105CID antiterminator BG02_1272 ENOG4105FDP GntR family transcriptional regulator BG02_1274 ENOG4105CE4 GlcNAc 6-P deacetylase BG02_128 ENOG4108XET gCN5-related N-acetyltransferase BG02_1281 ENOG4107ZE5 PPIases accelerate the folding of proteins BG02_1282 ENOG4105PTM secreted protein BG02_1283 ENOG4105J7I hydrolase BG02_1285 ENOG4105G6R Stage v sporulation protein ae BG02_1287 ENOG4105CZ3 stage V sporulation protein ad BG02_1288 ENOG41090VF Stage v sporulation protein ac BG02_1292 ENOG4105C8J )-transporter BG02_1293 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_1295 ENOG41082AN stage II sporulation protein BG02_1296 ENOG4105DZ1 carboxypeptidase BG02_1297 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG02_1298 ENOG4105DVE abc transporter atp-binding protein BG02_1304 ENOG4105D7N magnesium and cobalt transport protein CorA BG02_1309 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG02_1311 ENOG4105I3K Ferric uptake regulator, Fur family BG02_1312 ENOG4105MZ9 stage II sporulation protein m BG02_1316 ENOG4105CPC Aldo Keto reductase BG02_1318 ENOG4105RHY Pfam:UPF0157 BG02_1322 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BG02_1324 ENOG4105ETE Transcriptional regulator (LacI family BG02_1325 ENOG4108YM7 Gcn5-related n-acetyltransferase BG02_1329 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BG02_1330 ENOG4108R6K riboflavin synthase, subunit alpha BG02_1334 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BG02_1335 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BG02_1336 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BG02_1337 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BG02_1339 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG02_1341 ENOG4105DFD Na H antiporter BG02_1342 ENOG4105CGH 5'-nucleotidase BG02_1350 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BG02_1353 ENOG4108IXY short-chain dehydrogenase reductase BG02_1354 ENOG41069FQ Metallo-beta-lactamase superfamily BG02_1356 ENOG4105II7 pyrroline-5-carboxylate reductase BG02_1357 ENOG4105EJQ L-serine dehydratase BG02_1361 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG02_1363 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BG02_1364 ENOG4105D9U N-acetyltransferase BG02_1366 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BG02_1367 ENOG4108QEG Membrane BG02_1368 ENOG4105CDA abc transporter atp-binding protein BG02_1369 ENOG4105E5Q amino acid AbC transporter BG02_1370 ENOG4108HW3 (ABC) transporter BG02_1372 ENOG4105G7B Protein of unknown function (DUF2992) BG02_1373 ENOG4105E09 nadh pyrophosphatase BG02_1375 ENOG4105C7S Dehydrogenase BG02_1376 ENOG4105CPP Dehydrogenase, E1 component BG02_1380 ENOG4107RDP Dehydrogenase BG02_1382 ENOG4108JUB Transcriptional regulator BG02_1384 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BG02_1387 ENOG4107QQR Sporulation BG02_1388 ENOG4105S1Z Stage IV sporulation protein B BG02_1389 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BG02_1391 ENOG4105DX0 Hemolysin A BG02_1393 ENOG4105CTB Polyprenyl synthetase BG02_1398 ENOG4108ZSR alkaline shock protein BG02_1399 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BG02_1404 ENOG410644B Stage III sporulation protein af BG02_1406 ENOG4105KQ4 Stage iii sporulation protein ad BG02_1407 ENOG4108CQH stage III sporulation protein AC BG02_1408 ENOG4105KR5 Stage iii sporulation protein BG02_1409 ENOG4105CD2 stage iii sporulation protein aa BG02_1414 ENOG4105DC7 peptidase M24 BG02_1417 ENOG4105CBJ Metal-dependent enzyme BG02_1418 ENOG4107YBY Hydrolase BG02_1423 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BG02_1424 ENOG4105WZW rhodanese family BG02_1428 ENOG41080TC multidrug resistance protein BG02_1435 ENOG4105CJ1 ABC, transporter BG02_1436 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BG02_144 ENOG410635A Membrane BG02_1442 ENOG4105C0D helicase BG02_145 ENOG4105KNA -acetyltransferase BG02_146 ENOG4108IQI permease BG02_1466 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BG02_1467 ENOG4105C3R Methionine synthase BG02_1469 ENOG4105C28 cystathionine BG02_1470 ENOG4105C28 cystathionine BG02_1474 ENOG4105C5X domain protein BG02_1476 ENOG4105DKQ ROK family BG02_1478 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BG02_148 ENOG4105F1N DNA alkylation repair BG02_1481 ENOG4108UTW Plays a role in the regulation of phosphate uptake BG02_1482 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BG02_1483 ENOG4105E2Z phosphate ABC transporter (Permease BG02_1484 ENOG4105C8U phosphate abc transporter BG02_1485 ENOG4105PWN phosphate abc transporter BG02_1486 ENOG4107RF6 penicillin-binding protein BG02_1488 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG02_1493 ENOG4105N80 Ferric uptake regulator, Fur family BG02_1495 ENOG4105FDK ABC transporter BG02_1496 ENOG4108JYZ YitT family BG02_1497 ENOG41069ZM Protein of unknown function (DUF2624) BG02_1502 ENOG4105EGD dinuclear metal center protein, YbgI family BG02_1505 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_1506 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BG02_1511 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BG02_1512 ENOG4105KG3 cytidine deaminase BG02_1513 ENOG4107YR5 Diacylglycerol kinase BG02_1515 ENOG4105CTJ Metal Dependent Phosphohydrolase BG02_1516 ENOG4105C9A Phoh family BG02_1518 ENOG41068P3 sporulation protein YqfC BG02_1519 ENOG4105KTH gatB Yqey BG02_1521 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BG02_1522 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BG02_1526 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BG02_1528 ENOG4105CSA Coproporphyrinogen iii oxidase BG02_1529 ENOG4105KVH Transcriptional regulator BG02_1534 ENOG4105TQK DNA polymerase iii, delta' subunit BG02_1536 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BG02_1537 ENOG4108UK2 deaminase BG02_1538 ENOG4105KQC Competence protein BG02_1540 ENOG4105DXX methyltransferase BG02_1542 ENOG4108WF2 Metal Dependent Phosphohydrolase BG02_1544 ENOG410812S Rna-binding protein BG02_1546 ENOG4105CQW ribosome biogenesis GTPase YqeH BG02_1547 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BG02_1549 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_1554 ENOG4108TVJ Nitroreductase BG02_1557 ENOG4105G6Z alkaline phosphatase BG02_1559 ENOG4108MUZ hydrolase BG02_156 ENOG4107RF6 penicillin-binding protein BG02_1566 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BG02_1567 ENOG4105MIR Phenylalanine 4-monooxygenase BG02_1569 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_1570 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_1578 ENOG4105S6R Iron-hydroxamate transporter permease subunit BG02_1579 ENOG4108V5C ABC transporter BG02_158 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BG02_1581 ENOG4108EKI Dehydrogenase BG02_1582 ENOG4105C28 cystathionine BG02_1588 ENOG4107XRG penicillin-binding protein BG02_1591 ENOG4105CFP Peptidase U32 BG02_1592 ENOG4105XYU peptidase (U32 family) BG02_1593 ENOG4108VQJ O-methyltransferase BG02_1594 ENOG4105HHA aminodeoxychorismate lyase BG02_1598 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG02_1600 ENOG4105C02 permease BG02_1603 ENOG41060CR BG02_1604 ENOG4105C7H Helicase, RecD TraA family BG02_1606 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BG02_1607 ENOG4105C3J Cysteine desulfurase BG02_1609 ENOG4105D1H recombination factor protein RarA BG02_1610 ENOG4108VCI transcription factor, rsfa family BG02_1611 ENOG4105CUZ uba thif-type nad fad binding protein BG02_1613 ENOG4105CUT histidyl-tRNA synthetase BG02_1616 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BG02_1618 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BG02_1619 ENOG41076HS cation diffusion facilitator family transporter BG02_1620 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BG02_1622 ENOG4105CKP Polysaccharide Biosynthesis Protein BG02_1623 ENOG4108QG2 Membrane BG02_1625 ENOG4105VIE preprotein translocase, subunit YajC BG02_1628 ENOG41061AI Protein of unknown function (DUF2905) BG02_1631 ENOG4108HUF Transporter BG02_1633 ENOG4108IPJ Membrane BG02_1634 ENOG4108IPJ Membrane BG02_1635 ENOG41082BM Transcriptional regulator, arsr family BG02_1640 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BG02_1641 ENOG4108IYU L-aspartate oxidase BG02_1644 ENOG4108RPX mosc domain containing protein BG02_1645 ENOG4105CQC Prephenate dehydratase BG02_1649 ENOG4105EWM Histidine kinase BG02_1652 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BG02_1655 ENOG4105X36 (ribosomal) protein BG02_1657 ENOG4105C03 ribonuclease BG02_166 ENOG4105P4J Allophanate hydrolase, subunit 1 BG02_1660 ENOG4107QMS site-determining protein BG02_1663 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BG02_1664 ENOG4105DFF Rod shape-determining protein mreb BG02_1668 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BG02_1669 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BG02_167 ENOG4107258 Transcriptional regulator BG02_1671 ENOG41068KH stage VI sporulation protein D BG02_1673 ENOG4105D52 delta-aminolevulinic acid dehydratase BG02_1678 ENOG4105K56 Transcriptional regulator BG02_1682 ENOG4108IUQ atp-dependent protease BG02_1688 ENOG4108QCI YvbH-like oligomerisation region BG02_169 ENOG4106N3A copper homeostasis protein cutc BG02_1692 ENOG4105M59 Phosphodiesterase, mj0936 family BG02_1693 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BG02_1695 ENOG4108XJQ germination protein BG02_1697 ENOG4108PCX Major Facilitator BG02_1699 ENOG4105KBX Transcriptional regulator, TetR family BG02_17 ENOG4107VC0 DNA alkylation repair enzyme BG02_170 ENOG4108ZRV stage ii sporulation protein p BG02_1702 ENOG4105PFC Transcriptional regulator BG02_1705 ENOG4105DZC cytosine deaminase BG02_1706 ENOG4105DZC cytosine deaminase BG02_1707 ENOG4105DEF Extracellular solute-binding protein, family 5 BG02_1708 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG02_171 ENOG4108ZHR arsR family transcriptional regulator BG02_1711 ENOG4108JQ7 (ABC) transporter BG02_1712 ENOG4108HRK Histidine kinase BG02_1713 ENOG4105DY9 regulatoR BG02_1716 ENOG41067S9 phage shock protein C, PspC BG02_1717 ENOG4108JCI Transcriptional regulator BG02_1719 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BG02_1720 ENOG4108Z40 Transcriptional regulator BG02_1721 ENOG4105RHA ABC transporter, permease BG02_1722 ENOG4108IUX (ABC) transporter BG02_1723 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BG02_1724 ENOG4105ER2 Ompa motb domain protein BG02_1725 ENOG4105ER2 Ompa motb domain protein BG02_1726 ENOG4105E14 MotA TolQ exbB proton channel BG02_1727 ENOG4108VXD carboxy-peptidase BG02_1729 ENOG4105E33 succinate dehydrogenase BG02_173 ENOG4105FDT acyl-CoA dehydrogenase BG02_1731 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BG02_1734 ENOG4105K63 Thioredoxin BG02_1735 ENOG4105C10 Electron transfer flavoprotein BG02_1736 ENOG4105BZJ Electron transfer flavoprotein BG02_1737 ENOG41060WC Enoyl-CoA hydratase BG02_1738 ENOG4107Z3H Transcriptional regulator, TetR family BG02_1739 ENOG4105CEY Amp-dependent synthetase and ligase BG02_1741 ENOG4105J76 Periplasmic binding protein BG02_1742 ENOG4105S6R Iron-hydroxamate transporter permease subunit BG02_1751 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_1754 ENOG4105DR4 Methyltransferase BG02_1757 ENOG4105KFN sortase, SrtB family BG02_1758 ENOG4105E0A ABC, transporter BG02_1761 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BG02_1763 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BG02_1765 ENOG4105FE9 pseudouridine synthase BG02_1768 ENOG4105DCG PHP domain protein BG02_177 ENOG4105DWD nucleoside recognition domain protein BG02_1775 ENOG4105C5S asparaginyl-tRNA synthetase BG02_1776 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BG02_1778 ENOG4108RWN rrna methyltransferase BG02_1785 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_1786 ENOG4105CW7 secretion protein, HlyD family BG02_1787 ENOG4108JGH Tetr family transcriptional regulator BG02_1788 ENOG4105CN9 Peptidase m42 family protein BG02_1792 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BG02_1793 ENOG4105C22 threonyL-tRNA synthetase BG02_1794 ENOG4108TDW sporulation protein YtxC BG02_1798 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BG02_1799 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BG02_1800 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BG02_1802 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BG02_1803 ENOG4105C2M dna polymerase I BG02_1804 ENOG4105BZU Histidine kinase BG02_1805 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_1809 ENOG4108HMX isocitrate dehydrogenase (NADP) BG02_1810 ENOG4105BZN citrate synthase BG02_1812 ENOG4108REF Sporulation integral membrane protein ytvi BG02_1813 ENOG4105FS0 cytoplasmic membrane protein BG02_1818 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BG02_1819 ENOG4105C6K Malic enzyme BG02_1820 ENOG4105C0B DNA polymerase III (alpha subunit) BG02_1821 ENOG4105VV2 BG02_1823 ENOG4105SFS phosphoesterase RecJ domain protein BG02_183 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BG02_1830 ENOG4105DC7 peptidase M24 BG02_1837 ENOG4105Z7P Acetyltransferase (GNAT) family BG02_1838 ENOG41082W1 Cupin 2, conserved barrel domain protein BG02_1840 ENOG4105VZ8 Transcriptional regulator BG02_1844 ENOG4107YZX Universal stress protein BG02_1853 ENOG4108JYZ YitT family BG02_1857 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BG02_1859 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BG02_1860 ENOG4105KBJ sporulation protein ytfj BG02_1863 ENOG4105EFZ amidohydrolase BG02_1865 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BG02_1870 ENOG4106KR7 LysR family Transcriptional regulator BG02_1872 ENOG4105U5Y Transcriptional regulator BG02_1873 ENOG4105U5Y Transcriptional regulator BG02_1875 ENOG4105C28 cystathionine BG02_1879 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BG02_1881 ENOG4105EMN RNA polymerase sigma factor BG02_1884 ENOG4105F1V Acetoin utilization protein BG02_1885 ENOG4105W87 Cbs domain BG02_1886 ENOG4105DGU Histone deacetylase BG02_1888 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_1890 ENOG4107SNB ankyrin repeat protein YahD BG02_1891 ENOG4105EP9 oxidoreductase BG02_1897 ENOG4105ETE Transcriptional regulator (LacI family BG02_19 ENOG4107VMI polysaccharide deacetylase BG02_1901 ENOG4105C88 aminopeptidase BG02_1910 ENOG4108VDD TRNA binding domain protein BG02_1916 ENOG4105C8F Beta-lactamase domain protein BG02_1919 ENOG4108V15 phosphotransferase enzyme family BG02_1920 ENOG4108IUM Glycogen debranching enzyme BG02_1922 ENOG4107QSE Dipeptidase BG02_1923 ENOG4107QSE Dipeptidase BG02_1924 ENOG4105YW5 deoR family transcriptional regulator BG02_1927 ENOG4105CBX hi0933 family BG02_1934 ENOG4108VJ1 Transcriptional regulator (CarD family BG02_1935 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BG02_1936 ENOG4105CSC Glucose uptake protein BG02_1939 ENOG4108ZAF Molybdopterin BG02_1940 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BG02_1941 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG02_1943 ENOG4105D06 uba thif-type nad fad binding protein BG02_1944 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BG02_1948 ENOG41085GJ domain protein BG02_1950 ENOG4105DWV Homoserine O-trans-acetylase BG02_1952 ENOG4108B31 Spore germination protein BG02_1958 ENOG410605W Major Facilitator BG02_1959 ENOG4107S91 Sodium hydrogen exchanger BG02_1960 ENOG4105NCW Trka-c domain protein BG02_1963 ENOG4105C19 ABC transporter BG02_1967 ENOG4105N5T Radical SAM Protein BG02_1969 ENOG4105DA5 (ABC) transporter BG02_1975 ENOG4105E8V Alpha Beta Hydrolase Fold protein BG02_1976 ENOG4108Z0R Transferase BG02_1977 ENOG4105YVM Phosphoesterase, PA-phosphatase related BG02_1978 ENOG4105BZF Glycosyl transferase (Group 1 BG02_198 ENOG4105E2A Dehydrogenase BG02_1980 ENOG4108RIR Molybdenum cofactor biosynthesis protein BG02_1990 ENOG4105EGD dinuclear metal center protein, YbgI family BG02_1991 ENOG4105BZU Histidine kinase BG02_1992 ENOG4105BZU Histidine kinase BG02_1993 ENOG4107S9D Alpha beta hydrolase BG02_1994 ENOG4107T7U Sulfatase BG02_1998 ENOG4105D2X ABC transporter substrate-binding protein BG02_2000 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BG02_2004 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BG02_201 ENOG4108IJ0 Aspartate ammonia-lyase BG02_2011 ENOG4108V2W Carbonate dehydratase BG02_2013 ENOG4105C4M (Ubiquinol oxidase) subunit I BG02_2014 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BG02_202 ENOG4105HDK L-asparaginase BG02_2023 ENOG41087YS Phage shock protein A BG02_203 ENOG4108IMY Transcriptional regulator BG02_2030 ENOG4105BZU Histidine kinase BG02_2031 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_2036 ENOG4108UGV hypoxanthine phosphoribosyltransferase BG02_2037 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BG02_2044 ENOG4107ZTW SNARE associated Golgi BG02_2047 ENOG4105C19 ABC transporter BG02_2048 ENOG41086D8 Transcriptional regulator BG02_205 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BG02_2059 ENOG4105C6Z Gluconate BG02_206 ENOG4105CUB amino acid BG02_2060 ENOG4105FDP GntR family transcriptional regulator BG02_2064 ENOG41069H0 dihydroorotase EC 3.5.2.3 BG02_2070 ENOG4105DTQ mandelate racemase muconate lactonizing BG02_2072 ENOG4108IPT Naphthoate synthase BG02_2073 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BG02_2074 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BG02_2075 ENOG4105E4F Isochorismate synthase BG02_2076 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BG02_2078 ENOG4105VEQ Cold shock protein BG02_208 ENOG4105II7 pyrroline-5-carboxylate reductase BG02_2083 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BG02_2085 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BG02_2087 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG02_21 ENOG4108ZCF integral membrane protein BG02_210 ENOG4105C6K Malic enzyme BG02_2106 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BG02_2116 ENOG4105KT7 mgtC SapB transporter BG02_2118 ENOG4107PBV potassium channel BG02_2119 ENOG4107QYV phosphohexose isomerase BG02_2120 ENOG4105WG9 Conserved Protein BG02_2122 ENOG4105CHM Aminotransferase BG02_2123 ENOG4108ZB6 transcriptional regulator AsnC family BG02_2124 ENOG4105C5I Dehydrogenase BG02_2125 ENOG4108MUZ hydrolase BG02_2127 ENOG4105C87 Aminotransferase class I and II BG02_213 ENOG4108NHD germination protein BG02_2130 ENOG4105Y38 Kinase-associated protein B BG02_2132 ENOG4107R3E Citrate transporter BG02_2135 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BG02_2136 ENOG4105KA0 thioesterase Superfamily protein BG02_214 ENOG4108NHD germination protein BG02_2140 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BG02_2144 ENOG41069ER domain protein BG02_2147 ENOG4105CEP NADH dehydrogenase BG02_215 ENOG4108Q8B Spore germination protein BG02_2153 ENOG4105EWC Purine nucleoside phosphorylase BG02_2156 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BG02_2160 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG02_2161 ENOG4105C4B ABC transporter, permease BG02_2162 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BG02_2171 ENOG41083MR nifu domain-containing protein BG02_2174 ENOG4108W5N phosphatidylglycerophosphatase a BG02_2176 ENOG4105DYS nad(p)h dehydrogenase (quinone) BG02_2177 ENOG4105D4U had-superfamily hydrolase, subfamily iia BG02_2180 ENOG4105CBT Fructose-1,6-bisphosphatase BG02_2183 ENOG4105MMD transcriptional regulator BG02_2184 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BG02_2185 ENOG4107TXC Transcriptional regulator BG02_2186 ENOG41090T1 Membrane BG02_2190 ENOG4105FAA peptidase M23 BG02_2192 ENOG4105KZD Domain of unknown function (DUF1805) BG02_2193 ENOG4107R8B 5'-nucleotidase BG02_2196 ENOG4105DIW FeS assembly protein SUFB BG02_2197 ENOG4108UNV SUF system FeS assembly protein, NifU family BG02_2198 ENOG4105C9B Cysteine desulfurase BG02_2199 ENOG4105JRK feS assembly protein SufD BG02_22 ENOG4105E0M Sulfatase BG02_220 ENOG4105CSV Glutaminase BG02_2200 ENOG4105C3K feS assembly ATPase SufC BG02_2201 ENOG4105D01 (LipO)protein BG02_2202 ENOG4105D01 (LipO)protein BG02_2203 ENOG4108UMI ABC transporter, permease BG02_2209 ENOG41080E8 Transcriptional regulator, Spx MgsR family BG02_2218 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG02_2224 ENOG4108W8B Beta-lactamase domain protein BG02_2225 ENOG4105C1G acyl-Coa dehydrogenase BG02_2226 ENOG4105CHU acetyl-coa acetyltransferase BG02_2229 ENOG4105DZ1 carboxypeptidase BG02_2233 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BG02_2237 ENOG4108SUT Major Facilitator Superfamily BG02_2238 ENOG4107R7I amino acid BG02_2240 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BG02_2242 ENOG4107AYK membrAne BG02_2249 ENOG4107ZTW SNARE associated Golgi BG02_2251 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BG02_2252 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_2253 ENOG4105BZU Histidine kinase BG02_2255 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BG02_2258 ENOG4105VG1 fes assembly suf system protein BG02_2259 ENOG4105D4Y metalloprotease BG02_2263 ENOG4107S91 Sodium hydrogen exchanger BG02_2264 ENOG4105NCW Trka-c domain protein BG02_2268 ENOG4108URH decarboxylase BG02_2273 ENOG4105D9N nucleoside BG02_2274 ENOG4105D9N nucleoside BG02_2277 ENOG4108RYK Nad-dependent epimerase dehydratase BG02_228 ENOG4105CGH 5'-nucleotidase BG02_2282 ENOG4105CV8 reductase BG02_2283 ENOG4105F27 Major Facilitator BG02_2284 ENOG4105KVH Transcriptional regulator BG02_2287 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BG02_2288 ENOG4105D4A Cell wall formation (By similarity) BG02_229 ENOG4105CH6 catalase BG02_2290 ENOG4105C8Q Methyl-accepting chemotaxis BG02_2292 ENOG4105WMR Protein CrcB homolog BG02_2293 ENOG4105WMR Protein CrcB homolog BG02_2296 ENOG4108MK9 spermidine N(1)-acetyltransferase BG02_2297 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BG02_23 ENOG4105C5H ABC transporter BG02_2300 ENOG4108IPW abc transporter atp-binding protein BG02_2301 ENOG4105CM4 permease protein BG02_2306 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BG02_2308 ENOG4105XZU Preprotein translocase, subunit SecG BG02_2309 ENOG41067MG lrgb family BG02_231 ENOG4105CHJ isochorismatase hydrolase BG02_2328 ENOG4105EFC phage portal protein HK97 family BG02_2333 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG02_2335 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BG02_2336 ENOG4105CP7 Triose-phosphate isomerase BG02_2341 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_2345 ENOG41090VF Stage v sporulation protein ac BG02_2346 ENOG4105CZ3 stage V sporulation protein ad BG02_2349 ENOG4105H67 Protein of unknown function (DUF421) BG02_2350 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BG02_2351 ENOG4105KRI phosphocarrier protein (HPr BG02_2353 ENOG4105CHW UPF0052 protein BG02_2355 ENOG4108Z4K mutator MutT protein BG02_2357 ENOG4105C3M thioredoxin reductase BG02_2359 ENOG4108S4C acetyltransferase BG02_2363 ENOG41086DT Membrane protein of unknown function BG02_2365 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG02_2366 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BG02_2367 ENOG4105D7V transposase BG02_237 ENOG41090MY MarR family Transcriptional regulator BG02_2370 ENOG4107TXC Transcriptional regulator BG02_2374 ENOG4105HMI Membrane BG02_2375 ENOG4105DUM transcriptional regulator, lysR family BG02_2377 ENOG4108WS4 fmn reductase BG02_2380 ENOG4105BZ1 (ABC) transporter BG02_2382 ENOG4105CN1 protease BG02_2383 ENOG4105CRP Part of the ABC transporter FtsEX involved in BG02_2384 ENOG4105CAK Cell division ATP-binding protein ftsE BG02_2386 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BG02_2387 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BG02_2388 ENOG4105MS2 ribosomal subunit Interface protein BG02_2389 ENOG4105VEQ Cold shock protein BG02_2390 ENOG41081UC Inherit from COG: Competence protein BG02_2393 ENOG4105KVH Transcriptional regulator BG02_2395 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BG02_2396 ENOG4108KGH TRANSCRIPTIONal BG02_2397 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BG02_2398 ENOG4105C6Y Udp-glucose 6-dehydrogenase BG02_2399 ENOG4105ESV Glycosyl transferase, family 4 BG02_2401 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BG02_2404 ENOG410901P UPF0249 protein BG02_2405 ENOG4105F8D glycoside hydrolase family 4 BG02_2406 ENOG4105VCP PTS System BG02_2407 ENOG4105CK1 PTS System BG02_2409 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BG02_2410 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BG02_2411 ENOG4105VCP PTS System BG02_2413 ENOG4105VZJ PTS System BG02_2416 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_2417 ENOG4105ECB domain protein BG02_2418 ENOG4107RSM transcriptional regulator BG02_2426 ENOG4105DAA L-lactate BG02_2428 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BG02_2430 ENOG4105E0M Sulfatase BG02_2439 ENOG4105C94 Transporter BG02_2440 ENOG41069ER domain protein BG02_2445 ENOG4105KBK Zinc finger, swim domain protein BG02_2446 ENOG4105C0D helicase BG02_245 ENOG4108606 TspO/MBR family BG02_2452 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_2454 ENOG4107RBB ABC transporter, permease BG02_2455 ENOG4105C19 ABC transporter BG02_2459 ENOG4105CXY transporter BG02_246 ENOG4105CVP deoxyribo-dipyrimidine photolyase BG02_2462 ENOG4105BZU Histidine kinase BG02_2463 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_2464 ENOG4105CMR udp-glucose 4-epimerase BG02_2467 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BG02_2468 ENOG4105EY8 ABC transporter BG02_2478 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BG02_2480 ENOG4105FRN stage II sporulation protein BG02_2483 ENOG4105DY9 regulatoR BG02_2484 ENOG4108IUW ABC transporter BG02_2488 ENOG4106778 Protein of unknown function (DUF1146) BG02_2489 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BG02_249 ENOG4108TWJ NADH dehydrogenase subunit 5 BG02_2490 ENOG4105C8S subunit m BG02_2491 ENOG4105D65 subunit l BG02_2496 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BG02_2497 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BG02_2499 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BG02_25 ENOG4105EYF MMPL domain protein BG02_250 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BG02_2500 ENOG4105BZU Histidine kinase BG02_2510 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BG02_2511 ENOG41062M3 atp synthase BG02_2516 ENOG4108YZG isomerase BG02_2519 ENOG4108VGI doxx family BG02_252 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BG02_2520 ENOG4107XC4 flavin reductase domain protein, FMN-binding BG02_2523 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BG02_2525 ENOG4108ZXQ stage ii sporulation protein r BG02_2526 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BG02_2527 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BG02_253 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BG02_2530 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BG02_2531 ENOG4105CBT Fructose-1,6-bisphosphatase BG02_2532 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BG02_2539 ENOG4105C1G acyl-Coa dehydrogenase BG02_254 ENOG4105DSE periplasmic solute binding protein BG02_2540 ENOG4105C1G acyl-Coa dehydrogenase BG02_2541 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BG02_2543 ENOG4105DF6 Fe-S oxidoreductase BG02_2546 ENOG4105BZU Histidine kinase BG02_255 ENOG4105CC5 ABC transporter BG02_2551 ENOG4105BZU Histidine kinase BG02_2552 ENOG4105KCT ABC transporter BG02_2553 ENOG4108M15 ABC transporter BG02_2554 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BG02_2558 ENOG4105IIU Aminopeptidase BG02_256 ENOG4105DIK (ABC) transporter BG02_2562 ENOG4105EMN RNA polymerase sigma factor BG02_2564 ENOG410684U Domain of unknown function (DUF1934) BG02_2568 ENOG4105CYW agmatinase BG02_2570 ENOG4105DXB Major Facilitator superfamily BG02_2571 ENOG4107SWG transcriptional regulator MERR family BG02_2572 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BG02_2573 ENOG4105BZ4 penicillin-binding protein BG02_2574 ENOG4108XFG YwhD family BG02_2575 ENOG4108Z4T Peptidase M50 BG02_2576 ENOG41069HH 4-oxalocrotonate tautomerase BG02_2577 ENOG4105DCI Phosphohydrolase BG02_2578 ENOG4108MES Periplasmic binding protein BG02_2579 ENOG4105E0A ABC, transporter BG02_2580 ENOG4105EHG Permease protein BG02_2581 ENOG4105DQ5 transport system permease protein BG02_2582 ENOG4105DQ5 transport system permease protein BG02_2584 ENOG4108VCI transcription factor, rsfa family BG02_2587 ENOG4108IJ2 phosphate acetyltransferase BG02_2590 ENOG4108VKI Cell wall hydrolase BG02_2594 ENOG4107SVH Potassium channel protein BG02_2596 ENOG410667J hydrolase BG02_2597 ENOG4105VCH membrane BG02_2599 ENOG4108TU7 Inherit from COG: (ABC) transporter BG02_26 ENOG4105EYF MMPL domain protein BG02_2600 ENOG4105CJ1 ABC, transporter BG02_2601 ENOG41090WU lipolytic protein G-D-S-L family BG02_2604 ENOG4105D6E homoserine dehydrogenase BG02_2609 ENOG4108Y4K DNA-binding transcriptional activator BG02_2611 ENOG4105WH1 Two component transcriptional regulator luxr family BG02_2612 ENOG4105BZU Histidine kinase BG02_2613 ENOG4105BZU Histidine kinase BG02_2614 ENOG4105DWF phosphomethylpyrimidine kinase BG02_2615 ENOG4105BZU Histidine kinase BG02_2616 ENOG4105VCD cytoplasmic protein BG02_2617 ENOG4105D22 carbon starvation protein BG02_2618 ENOG4105DY9 regulatoR BG02_2619 ENOG41079KZ Major Facilitator Superfamily BG02_262 ENOG4105D6J arsenicaL-resistance protein BG02_2623 ENOG4105EN6 Membrane BG02_2624 ENOG4106YBV Methyl-accepting chemotaxis BG02_2626 ENOG4108S4H thioesterase Superfamily protein BG02_2628 ENOG4105JEU Glycosyl transferase, family 2 BG02_2629 ENOG4105C5H ABC transporter BG02_263 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_2634 ENOG4105CKK Glycosyl transferase, family 2 BG02_2635 ENOG41067SE Tetr family transcriptional regulator BG02_2637 ENOG4105E0X reductase BG02_2638 ENOG4106F5Q Membrane BG02_264 ENOG41085FC arsR family transcriptional regulator BG02_2641 ENOG4105DY9 regulatoR BG02_2642 ENOG4108HRK Histidine kinase BG02_2643 ENOG4107RGD Major Facilitator superfamily BG02_2646 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG02_2648 ENOG4105IW1 AmiS UreI transporter BG02_2650 ENOG4105CMR udp-glucose 4-epimerase BG02_2651 ENOG4108UT2 hemolysin iii BG02_2653 ENOG4105C1J atp-dependent rna helicase BG02_2656 ENOG4105DPN Oligoendopeptidase f BG02_2660 ENOG4105C0H protease BG02_2661 ENOG4105Q2H domain protein BG02_2664 ENOG4105BZU Histidine kinase BG02_2665 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_2671 ENOG4105CDU Replicative dna helicase BG02_2673 ENOG4105BZR domain protein BG02_2674 ENOG4108XMW Membrane BG02_2676 ENOG4108UUM single-stranded DNA-binding protein BG02_2678 ENOG4105C3G gtp-binding protein BG02_2679 ENOG4105VDK protein, conserved in bacteria BG02_268 ENOG4105F7F Chaperone BG02_2680 ENOG4105D8X mechanosensitive ion channel BG02_2681 ENOG4108ZDA Sporulation protein YyaC BG02_2682 ENOG4105FA0 parb-like partition protein BG02_2683 ENOG4107QJE Chromosome Partitioning Protein BG02_2687 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BG02_2689 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BG02_2693 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BG02_2694 ENOG410848D S4 domain protein YaaA BG02_2697 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BG02_27 ENOG41082JN Transcriptional regulator BG02_270 ENOG4105CHR reductase BG02_2705 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BG02_271 ENOG4108YXU transcriptional regulator AsnC family BG02_2712 ENOG4105ZMH deoxynucleoside kinase BG02_2714 ENOG4105GTG Isochorismatase BG02_2715 ENOG4108Z6B deaminase BG02_2716 ENOG4105C6E dna polymerase iii BG02_2720 ENOG41067KS pro-sigma K processing BG02_2728 ENOG4105CXN decarboxylase BG02_2730 ENOG4105FA2 dna polymerase iii BG02_2731 ENOG4105MA4 psp1 domain protein BG02_2733 ENOG41060K3 Methyltransferase BG02_2735 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BG02_2736 ENOG4105KRN Transcriptional regulator, abrb family BG02_2738 ENOG4105F8V Hydrolase, tatD family BG02_2739 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BG02_2741 ENOG4105XFA sporulation peptidase YabG BG02_2742 ENOG4105W42 Veg protein BG02_2745 ENOG4105DFT pur operon repressor BG02_2746 ENOG4105KME endoribonuclease L-psp BG02_2749 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BG02_2750 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BG02_2752 ENOG4108JA2 transcriptioN-repair coupling factor BG02_2753 ENOG4108M14 stage v sporulation protein t BG02_2755 ENOG4108IY2 MazG family BG02_2756 ENOG41082I2 s4 domain protein BG02_2757 ENOG4105VYY sporulation protein yabp BG02_2760 ENOG41060GV RNA binding s1 domain protein BG02_2764 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BG02_2765 ENOG4108UGV hypoxanthine phosphoribosyltransferase BG02_2766 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BG02_2769 ENOG4105C6T cysteine synthase BG02_2770 ENOG4105CRQ synthase (Component I) BG02_2771 ENOG4105DDQ anthranilate synthase BG02_2772 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BG02_2773 ENOG4105EEI dihydropteroate synthase BG02_2774 ENOG4105KRF dihydroneopterin aldolase BG02_2775 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BG02_2777 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BG02_2784 ENOG4108Z0C Uvrb UvrC protein BG02_2787 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BG02_2789 ENOG4105CTP PilT protein domain protein BG02_2793 ENOG4105D7W serine acetyltransferase BG02_2796 ENOG4105C2N RNA methyltransferase TrmH family group 3 BG02_2797 ENOG4105M0M Tetracycline resistance protein BG02_2798 ENOG4105QIV RNA polymerase BG02_2800 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BG02_2805 ENOG4107Y49 methyltransferase BG02_2807 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BG02_2808 ENOG4105XPM ribosomal protein BG02_2829 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BG02_2834 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BG02_2836 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BG02_2838 ENOG41067V7 50S ribosomal protein L36 BG02_2844 ENOG4108JJB ABC transporter BG02_2845 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BG02_2846 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BG02_285 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BG02_2851 ENOG4105D1F ATP-binding protein BG02_2854 ENOG4108NMV polysaccharide deacetylase BG02_286 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_2872 ENOG4105C8B TIGR00159 family BG02_2873 ENOG4107U5W ybbr family BG02_2875 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BG02_2876 ENOG4108VQT Alpha beta hydrolase fold protein BG02_2878 ENOG4105CMG Carbohydrate kinase BG02_2879 ENOG4105CMG Carbohydrate kinase BG02_288 ENOG4105IIP Membrane BG02_2881 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BG02_2882 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BG02_2890 ENOG4108PSK reductase BG02_2891 ENOG4108UMI ABC transporter, permease BG02_2892 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG02_2893 ENOG4105D01 (LipO)protein BG02_2894 ENOG4105EE1 crotonyl-CoA reductase BG02_2896 ENOG4105IQ5 FAD linked oxidase domain protein BG02_2899 ENOG4105C2C drug resistance transporter, Bcr CflA BG02_2900 ENOG4105C2C drug resistance transporter, Bcr CflA BG02_2903 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG02_2904 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG02_2905 ENOG4105C3U ABC transporter BG02_2906 ENOG4108JQ7 (ABC) transporter BG02_2912 ENOG4108J59 Extracellular solute-binding protein, family 5 BG02_2913 ENOG4108J59 Extracellular solute-binding protein, family 5 BG02_2915 ENOG4105II7 pyrroline-5-carboxylate reductase BG02_2916 ENOG4107XDY Nicotinamide Mononucleotide Transporter BG02_2918 ENOG4105E0C molybdate abc transporter BG02_2919 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG02_292 ENOG4105K6H D-cysteine desulfhydrase BG02_2920 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG02_2921 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BG02_2924 ENOG4105EGI Transcriptional regulator BG02_2928 ENOG4105F6E Acyl-transferase BG02_2932 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BG02_2935 ENOG4108RE7 deoxyribonuclease BG02_2936 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BG02_2940 ENOG4105C5H ABC transporter BG02_2943 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BG02_2945 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG02_2946 ENOG4105C3U ABC transporter BG02_2947 ENOG410667J hydrolase BG02_2948 ENOG4108JQ7 (ABC) transporter BG02_2952 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BG02_2953 ENOG4105ERH Fumarylacetoacetate hydrolase BG02_2955 ENOG4108SC4 )-transporter BG02_2956 ENOG4105CPF Cell wall formation (By similarity) BG02_2957 ENOG4105CPF Cell wall formation (By similarity) BG02_2958 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BG02_2960 ENOG4107ZXI Rhomboid family BG02_2963 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BG02_2964 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BG02_2966 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BG02_298 ENOG4105VZ8 Transcriptional regulator BG02_2986 ENOG4105K8N protein family UPF0079, ATPase BG02_2987 ENOG41072GX Peptidase M22 Glycoprotease BG02_2988 ENOG410801F ribosomal-protein-alanine acetyltransferase BG02_2989 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BG02_2990 ENOG4105C5H ABC transporter BG02_2993 ENOG4108TYN CAAX amino terminal protease family protein BG02_2997 ENOG4105C7N Xanthine uracil vitamin C permease BG02_2999 ENOG4105BZU Histidine kinase BG02_3 ENOG4105E09 nadh pyrophosphatase BG02_3005 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BG02_301 ENOG4108NNI Beta-lactamase domain-containing protein BG02_3011 ENOG4108SHN Glycosyl transferase, family 2 BG02_3018 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG02_302 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BG02_3022 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_3027 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BG02_3028 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BG02_3029 ENOG4105C83 adenylosuccinate lyase BG02_3031 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BG02_3036 ENOG4108V3E phosphoribosylglycinamide formyltransferase BG02_3038 ENOG4105C12 Phosphoribosylglycinamide synthetase BG02_304 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG02_3043 ENOG4105C4R Atp-dependent dna helicase BG02_3049 ENOG4108W2Y isochorismatase BG02_305 ENOG4105JQZ Methyltransferase BG02_3050 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BG02_3051 ENOG4108UMI ABC transporter, permease BG02_3052 ENOG4105D01 (LipO)protein BG02_3056 ENOG4105D0U Arsenite-activated ATPase (ArsA) BG02_3057 ENOG410834F Transcriptional regulator BG02_3062 ENOG4105CBD Diacylglycerol kinase BG02_3063 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BG02_3064 ENOG4108JPW Aminotransferase BG02_3066 ENOG4105C26 Dehydrogenase BG02_3067 ENOG4105KPY Small multidrug resistance protein BG02_3071 ENOG4105D9N nucleoside BG02_3072 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BG02_3075 ENOG4108W15 Protein of unknown function (DUF1456) BG02_3078 ENOG4105DTQ mandelate racemase muconate lactonizing BG02_3079 ENOG4105DFD Na H antiporter BG02_308 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BG02_3084 ENOG4105D3R alkyl hydroperoxide reductase BG02_3085 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BG02_3087 ENOG4107W7X Aldolase BG02_3088 ENOG4105EHG Permease protein BG02_3089 ENOG4105DQ5 transport system permease protein BG02_309 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BG02_3090 ENOG4108V5C ABC transporter BG02_3094 ENOG4106UIA BG02_3095 ENOG4106UIA BG02_3099 ENOG4105BZU Histidine kinase BG02_31 ENOG4105CIH Imidazole acetol-phosphate transaminase BG02_3103 ENOG410756H nucleotidyltransferase BG02_3104 ENOG4105D2S major facilitator superfamily BG02_3107 ENOG4105E5Q amino acid AbC transporter BG02_3108 ENOG4105EAB amino acid AbC transporter BG02_3110 ENOG4105C8Q Methyl-accepting chemotaxis BG02_3111 ENOG4105C8Q Methyl-accepting chemotaxis BG02_3113 ENOG4105CI1 PTS System BG02_3119 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BG02_312 ENOG4105BZU Histidine kinase BG02_3122 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BG02_3125 ENOG4105C5H ABC transporter BG02_3130 ENOG41062JF Transcriptional regulator BG02_3134 ENOG4105DEU major facilitator superfamily BG02_3137 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BG02_3140 ENOG4108N0M stress protein BG02_3141 ENOG4106FN3 tellurium resistance protein BG02_3142 ENOG4106FN3 tellurium resistance protein BG02_3143 ENOG4107TS3 membrane protein, TerC BG02_3144 ENOG4108TTB tellurium resistance protein BG02_3148 ENOG4105KJF protein tyrosine phosphatase BG02_315 ENOG4108U05 Transcriptional regulator BG02_3150 ENOG4107U9T Pfam:Ribonuclease_BN BG02_3151 ENOG4105C59 p-type ATPase BG02_3152 ENOG4108IPJ Membrane BG02_3154 ENOG4105C3F Signal peptidase i BG02_3157 ENOG4107ZTW SNARE associated Golgi BG02_316 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BG02_3160 ENOG410606W general stress protein BG02_3161 ENOG4105UPD Calcium Proton BG02_3169 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BG02_3170 ENOG4105VTR Integrase BG02_318 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BG02_319 ENOG4105DJB Major Facilitator Superfamily BG02_32 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BG02_320 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BG02_321 ENOG4107QR9 Iron-sulfur cluster binding protein BG02_3229 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BG02_323 ENOG4106P55 Transcriptional regulator BG02_3231 ENOG4108JUB Transcriptional regulator BG02_3233 ENOG4108IQI permease BG02_3239 ENOG4105CSV Glutaminase BG02_3241 ENOG4108A04 Beta-lactamase BG02_3244 ENOG4105CKK Glycosyl transferase, family 2 BG02_3246 ENOG4107QQG Dehydrogenase BG02_3247 ENOG4105C3I Nad-dependent epimerase dehydratase BG02_325 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BG02_3250 ENOG4105F1A Pyruvate formate-lyase BG02_3254 ENOG4105CI2 imidazolone-5-propionate hydrolase BG02_3255 ENOG4105ECP epimerase BG02_3261 ENOG41067AE Membrane-bound metal-dependent hydrolase BG02_3262 ENOG4105CEN a g-specific adenine glycosylase BG02_3263 ENOG4106BXE BG02_3267 ENOG4105BZ1 (ABC) transporter BG02_3268 ENOG4107NBY Membrane BG02_3269 ENOG4105CBC glutamate synthase BG02_3271 ENOG4108IUW ABC transporter BG02_3275 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BG02_3276 ENOG4105G5W regulator Fur family BG02_33 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BG02_3301 ENOG4108JQC penicillin-binding protein 1A BG02_3302 ENOG4107ZQN disulfide bond BG02_3304 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BG02_3306 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BG02_3307 ENOG4105BZU Histidine kinase BG02_3309 ENOG4105CYN Serine protein kinase BG02_331 ENOG4105TRI Hydrolase BG02_3314 ENOG4105C94 Transporter BG02_3317 ENOG4105DZ6 Band 7 protein BG02_3319 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BG02_3322 ENOG4105D4T Citrate transporter BG02_3326 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BG02_3327 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG02_3328 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BG02_3329 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BG02_3330 ENOG4105BZ7 extracellular solute-binding protein family 1 BG02_3331 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BG02_3332 ENOG4108STX response regulator BG02_3333 ENOG4105US7 Histidine kinase BG02_3338 ENOG4108MRH transcriptional regulatory protein BG02_3340 ENOG4105C6K Malic enzyme BG02_3342 ENOG4108UZ3 Transporter BG02_3343 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BG02_3345 ENOG4105BZU Histidine kinase BG02_3346 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_3348 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BG02_3349 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BG02_3350 ENOG4108JB9 formate dehydrogenase BG02_3355 ENOG4105CUB amino acid BG02_3357 ENOG4105C59 p-type ATPase BG02_3358 ENOG4105DAP Nicotinate phosphoribosyltransferase BG02_3365 ENOG41073R8 VanW family BG02_3366 ENOG4108KGH TRANSCRIPTIONal BG02_3367 ENOG4105D9N nucleoside BG02_3368 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BG02_3369 ENOG4105C37 (CBS) domain BG02_3370 ENOG4108IJ0 Aspartate ammonia-lyase BG02_3371 ENOG4105DAA L-lactate BG02_3374 ENOG4105DUX Transporter BG02_3375 ENOG4108MES Periplasmic binding protein BG02_3376 ENOG4105DQ5 transport system permease protein BG02_3377 ENOG4108IHU transport system permease protein BG02_3378 ENOG4105E0A ABC, transporter BG02_3379 ENOG4105DMQ Methyltransferase BG02_3381 ENOG4105EXW epimerase dehydratase BG02_3383 ENOG4107T89 von Willebrand factor, type A BG02_3384 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BG02_3385 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG02_3388 ENOG4105BZU Histidine kinase BG02_3389 ENOG4105D5Q Arginine ornithine antiporter BG02_339 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG02_3390 ENOG4107414 GntR family transcriptional regulator BG02_3391 ENOG4105C5Y PTS System BG02_3392 ENOG4105CG3 alpha amylase, catalytic region BG02_3395 ENOG4105E1K spore germination protein BG02_3397 ENOG4105CRN Aminoglycoside phosphotransferase BG02_3398 ENOG4105BZG amino acid carrier protein BG02_3399 ENOG4105CDA abc transporter atp-binding protein BG02_3400 ENOG4105CT1 (ABC) transporter BG02_3401 ENOG4105EAD ABC transporter BG02_3402 ENOG4105DRP amino acid AbC transporter BG02_3403 ENOG4108IQI permease BG02_3408 ENOG4105D29 Helix-turn-helix type 11 domain protein BG02_3409 ENOG4105NAE bifunctional deaminase-reductase domain protein BG02_3410 ENOG4105BZU Histidine kinase BG02_3413 ENOG4105CHH sulfate transporter BG02_3414 ENOG41068KF Universal stress protein BG02_3416 ENOG4105DEF Extracellular solute-binding protein, family 5 BG02_3418 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG02_3419 ENOG4108JQ7 (ABC) transporter BG02_3421 ENOG4105CXY transporter BG02_3422 ENOG41067TZ transcriptional regulator, MarR family BG02_3423 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_3424 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_3425 ENOG4105ETE Transcriptional regulator (LacI family BG02_3426 ENOG4108RVA ribokinase BG02_3428 ENOG4105C2J ABC transporter BG02_3429 ENOG4105CNN ABC, transporter BG02_3430 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BG02_3431 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BG02_3443 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG02_3444 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BG02_3445 ENOG41069ER domain protein BG02_3446 ENOG4105VZ8 Transcriptional regulator BG02_3447 ENOG4107D63 BG02_3449 ENOG4105DUX Transporter BG02_3453 ENOG4105C85 amino acid BG02_3454 ENOG4105C7N Xanthine uracil vitamin C permease BG02_346 ENOG4107QJQ Mate efflux family protein BG02_3462 ENOG4105BZ9 Cytochrome C oxidase, subunit I BG02_3463 ENOG4105E2S oxidase) subunit II BG02_3466 ENOG4106CAD Protein of unknown function (DUF3311) BG02_3467 ENOG4105E1V na solute symporter BG02_3470 ENOG4108NHD germination protein BG02_3471 ENOG4105CE1 Ferrous iron transport protein b BG02_3472 ENOG4105CE1 Ferrous iron transport protein b BG02_3473 ENOG4105CE1 Ferrous iron transport protein b BG02_3474 ENOG4105CVA phosphate BG02_3475 ENOG4105C8U phosphate abc transporter BG02_3476 ENOG4105E2Z phosphate ABC transporter (Permease BG02_349 ENOG4105MZU cell filamentation protein BG02_350 ENOG4105EQ0 Major Facilitator superfamily BG02_3504 ENOG41080XQ Signal transduction protein with cbs domains BG02_3508 ENOG4105ETU transcriptional activator (TenA BG02_351 ENOG4108JGH Tetr family transcriptional regulator BG02_3510 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BG02_3512 ENOG4108VEU Thiamine monophosphate synthase BG02_3513 ENOG41080HI glycine oxidase BG02_3516 ENOG4105D06 uba thif-type nad fad binding protein BG02_3517 ENOG4105DWF phosphomethylpyrimidine kinase BG02_3526 ENOG4108INS Transcriptional regulator BG02_3529 ENOG4105C7N Xanthine uracil vitamin C permease BG02_3536 ENOG4105C5Y PTS System BG02_354 ENOG4105C44 Serine transporter BG02_3543 ENOG4108B31 Spore germination protein BG02_3548 ENOG4107Y03 Nitroreductase BG02_3549 ENOG4105ED1 spovr family BG02_355 ENOG4105EJQ L-serine dehydratase BG02_3554 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BG02_3555 ENOG4105XTG Pfam:DUF156 BG02_3556 ENOG4105VFE sira family BG02_3557 ENOG4107TPS domain protein BG02_3558 ENOG4105VFE sira family BG02_3560 ENOG41085GJ domain protein BG02_3562 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BG02_3563 ENOG41087NI Sulfite exporter TauE/SafE BG02_3565 ENOG4108KGH TRANSCRIPTIONal BG02_357 ENOG4108JPW Aminotransferase BG02_3570 ENOG4105EMD TRANSCRIPTIONal BG02_3571 ENOG4105VCP PTS System BG02_3572 ENOG4105VZJ PTS System BG02_3576 ENOG41069ER domain protein BG02_3577 ENOG4107RBB ABC transporter, permease BG02_3578 ENOG4105C19 ABC transporter BG02_3584 ENOG4105WEF catalase BG02_3591 ENOG4107T5V SNARE associated Golgi BG02_3599 ENOG4107RWR Sodium hydrogen exchanger BG02_360 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BG02_3601 ENOG4106KNT transcriptional regulator BG02_3608 ENOG4108PCN EamA-like transporter family BG02_3609 ENOG4108YXU transcriptional regulator AsnC family BG02_3611 ENOG4105KPY Small multidrug resistance protein BG02_3612 ENOG4105KPY Small multidrug resistance protein BG02_3617 ENOG4105NF4 modulator of drug activity BG02_3618 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BG02_3619 ENOG4105E5W Transporter BG02_362 ENOG4105DVH amino acid BG02_3621 ENOG4107RKG DJ-1/PfpI family BG02_3622 ENOG4105CH6 catalase BG02_3624 ENOG4105D5Q Arginine ornithine antiporter BG02_3625 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BG02_3627 ENOG4105C26 Dehydrogenase BG02_3628 ENOG4105BZ1 (ABC) transporter BG02_3629 ENOG4105BZ1 (ABC) transporter BG02_3630 ENOG4105BZ1 (ABC) transporter BG02_3632 ENOG4105DRP amino acid AbC transporter BG02_3633 ENOG4105CDA abc transporter atp-binding protein BG02_3636 ENOG410839P BG02_3643 ENOG4107FQX Alpha-acetolactate decarboxylase BG02_3648 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG02_365 ENOG4108JQ1 Dehydrogenase BG02_3650 ENOG4105D4P Coproporphyrinogen iii oxidase BG02_3653 ENOG4105CHH sulfate transporter BG02_3661 ENOG4106AKK s-layer domain-containing protein BG02_3663 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG02_3664 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG02_3667 ENOG4105CGU Enoyl-CoA hydratase BG02_3670 ENOG4105DER m42 family BG02_3674 ENOG4105CTU Proline racemase BG02_3682 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG02_3685 ENOG4108JQ7 (ABC) transporter BG02_369 ENOG4108AEY RNA polymerase sigma factor BG02_3691 ENOG4105CSH Transporter BG02_3693 ENOG4108MRH transcriptional regulatory protein BG02_3702 ENOG4105CDU Replicative dna helicase BG02_3710 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_372 ENOG41082W1 Cupin 2, conserved barrel domain protein BG02_3720 ENOG4107P5I polyketide synthase BG02_3721 ENOG4108IG5 Transcriptional regulator BG02_3725 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BG02_3729 ENOG4105CMT Dihydroxyacetone kinase BG02_373 ENOG410874W AraC family transcriptional regulator BG02_3731 ENOG4105CMT Dihydroxyacetone kinase BG02_3732 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BG02_3733 ENOG410847I Transcriptional regulator, BadM Rrf2 family BG02_3738 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BG02_3751 ENOG4105WN5 stage II sporulation protein BG02_3753 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BG02_3755 ENOG4108MJI response regulator BG02_3756 ENOG4105BZU Histidine kinase BG02_3757 ENOG4105BZU Histidine kinase BG02_376 ENOG4105HIR S-layer domain protein BG02_3762 ENOG4105K8R UPF0145 protein BG02_3768 ENOG4107VRP DNA repair exonuclease BG02_3769 ENOG4106D4I domain protein BG02_3770 ENOG4105D7V transposase BG02_3773 ENOG4108IND Tetr family transcriptional regulator BG02_3774 ENOG4105EQ0 Major Facilitator superfamily BG02_3779 ENOG4108MUZ hydrolase BG02_3783 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BG02_3786 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BG02_3789 ENOG4105EMN RNA polymerase sigma factor BG02_3794 ENOG4105C57 major facilitator superfamily BG02_3795 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_3797 ENOG4105EEM helicase BG02_3798 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG02_3803 ENOG4105K59 histidine triad (HIT) protein BG02_3811 ENOG410905X membrane-flanked domain protein BG02_3813 ENOG4105CKV Membrane BG02_3823 ENOG410905X membrane-flanked domain protein BG02_3824 ENOG4105CKV Membrane BG02_3825 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BG02_3826 ENOG4105BZ4 penicillin-binding protein BG02_3827 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BG02_3829 ENOG4105C1Q protoporphyrinogen oxidase BG02_3834 ENOG4105NA0 Transcriptional regulator BG02_3837 ENOG4105ECB domain protein BG02_384 ENOG4108ISG Major Facilitator BG02_3843 ENOG4106AXD BG02_3844 ENOG4108RQ5 Beta-lactamase domain-containing protein BG02_3845 ENOG4105DF9 Lipoate-protein, ligase BG02_3847 ENOG4105CEY Amp-dependent synthetase and ligase BG02_3855 ENOG4105CNA YD repeat protein BG02_386 ENOG4107MII Sugar-specific transcriptional regulator TrmB BG02_3860 ENOG4105ENX hydrolase BG02_3862 ENOG4107RN3 metallophosphoesterase BG02_3863 ENOG4107TVP HD domain protein BG02_3865 ENOG4108AEY RNA polymerase sigma factor BG02_3866 ENOG41086D8 Transcriptional regulator BG02_387 ENOG4105CZM Major Facilitator BG02_3870 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_3875 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BG02_3876 ENOG4105C8Q Methyl-accepting chemotaxis BG02_3880 ENOG4105ZU5 s-layer protein BG02_3881 ENOG4107QP3 malate synthase g BG02_3884 ENOG4105VEQ Cold shock protein BG02_3887 ENOG4105XVF Competence transcription factor BG02_3890 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BG02_3891 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BG02_3899 ENOG4105ERH Fumarylacetoacetate hydrolase BG02_3904 ENOG4105CAQ asparagine synthetase BG02_3905 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BG02_3906 ENOG4105CH6 catalase BG02_3907 ENOG4105BZU Histidine kinase BG02_391 ENOG4105DA5 (ABC) transporter BG02_3911 ENOG4105QNR S1 RNA binding domain protein BG02_3913 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG02_3915 ENOG4107AYK membrAne BG02_3916 ENOG41073B9 BG02_3918 ENOG4108KP7 hydrolase BG02_392 ENOG41069JR BG02_3920 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BG02_3925 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG02_3926 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BG02_3929 ENOG4105C31 Tryptophanyl-tRNA synthetase BG02_3932 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BG02_3933 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BG02_3935 ENOG4108JQ7 (ABC) transporter BG02_3936 ENOG4105UQX Mate efflux family protein BG02_394 ENOG4105RXJ BG02_3940 ENOG4108ZCF integral membrane protein BG02_3942 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG02_3944 ENOG4105DPN Oligoendopeptidase f BG02_3947 ENOG4108Z18 K06886 hemoglobin BG02_3948 ENOG4105MIX Adenylate cyclase BG02_395 ENOG4105KPY Small multidrug resistance protein BG02_3951 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BG02_3952 ENOG4105EMS pseudouridine synthase BG02_3956 ENOG4105CNI cell division protein FtsW BG02_3958 ENOG4105K64 Glycosyl transferase, family 2 BG02_396 ENOG4105KBX Transcriptional regulator, TetR family BG02_3962 ENOG4107TVC Glycosyl transferase, family 2 BG02_3966 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BG02_3967 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BG02_3969 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BG02_3978 ENOG4108WVJ 2'-5' rna ligase BG02_398 ENOG4105CRW Short chain fatty acid transporter BG02_3983 ENOG4105CK7 Sodium proline symporter BG02_3984 ENOG4105CRQ synthase (Component I) BG02_3985 ENOG4105DDQ anthranilate synthase BG02_400 ENOG4105DYS nad(p)h dehydrogenase (quinone) BG02_4003 ENOG4105C7S Dehydrogenase BG02_4005 ENOG4105VZ8 Transcriptional regulator BG02_4016 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BG02_4018 ENOG4105DZ1 carboxypeptidase BG02_4019 ENOG4105VFR signal peptidase BG02_4025 ENOG4105C26 Dehydrogenase BG02_4026 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG02_4027 ENOG4105F38 ABC transporter, permease BG02_4028 ENOG4105D38 putrescine abc transporter BG02_4029 ENOG4107RUE extracellular solute-binding protein family 1 BG02_4031 ENOG4105EYF MMPL domain protein BG02_4033 ENOG4108YBP pseudouridine synthase BG02_4035 ENOG4105K4I Scp-like extracellular BG02_4036 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BG02_4037 ENOG4105CQB FAD linked oxidase domain protein BG02_4040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_4041 ENOG4105BZU Histidine kinase BG02_4042 ENOG4105JXH GntR family transcriptional regulator BG02_4046 ENOG4106A3R peptidase BG02_4048 ENOG4108QTI )-transporter BG02_4049 ENOG4107TS3 membrane protein, TerC BG02_4050 ENOG4105CZN Potassium uptake protein BG02_4051 ENOG410681C small acid-soluble spore protein BG02_4052 ENOG4108Z7G MaoC domain protein dehydratase BG02_4056 ENOG4105CHR reductase BG02_4058 ENOG4105MWK D-amino acid dehydrogenase, small subunit BG02_406 ENOG4108JJB ABC transporter BG02_4062 ENOG4105C4Y ABC transporter BG02_4064 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG02_4069 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BG02_407 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BG02_4072 ENOG4105E98 transcriptional regulator DeoR family BG02_4077 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BG02_4078 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BG02_4080 ENOG4105PXI polysaccharide deacetylase BG02_4082 ENOG4105BZU Histidine kinase BG02_4083 ENOG41090MY MarR family Transcriptional regulator BG02_4085 ENOG4106DF1 BG02_4087 ENOG4105BZU Histidine kinase BG02_4089 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BG02_4090 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BG02_4098 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BG02_4099 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG02_41 ENOG41069ER domain protein BG02_4101 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG02_4102 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BG02_4103 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BG02_4104 ENOG4105CZV ABC transporter BG02_4106 ENOG4105CJ1 ABC, transporter BG02_4114 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BG02_4115 ENOG4105EA8 2-Nitropropane dioxygenase BG02_4116 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BG02_4118 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BG02_412 ENOG4108K8S endonuclease I BG02_4123 ENOG4105NQC Flavodoxin BG02_4130 ENOG4107QMU Mate efflux family protein BG02_4131 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BG02_4137 ENOG4105CZN Potassium uptake protein BG02_4138 ENOG41063Y9 BG02_4139 ENOG4105KBJ sporulation protein ytfj BG02_4144 ENOG4105CM2 brancheD-chain amino acid aminotransferase BG02_4145 ENOG4105C7K acetolactate synthase BG02_4146 ENOG4108ZP8 Acetolactate synthase small subunit BG02_4147 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BG02_4149 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BG02_415 ENOG41067QW Transcriptional regulator BG02_4154 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BG02_4161 ENOG4107RVV histidinol phosphate phosphatase, hisj family BG02_4164 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BG02_4165 ENOG4105E0M Sulfatase BG02_4167 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BG02_417 ENOG4108Z66 YbaK ebsC protein BG02_4171 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BG02_4172 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BG02_4174 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BG02_4175 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BG02_4176 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BG02_4177 ENOG4105C8J )-transporter BG02_418 ENOG4105CUT histidyl-tRNA synthetase BG02_4181 ENOG4105DFD Na H antiporter BG02_4185 ENOG4105ENE Histidine kinase BG02_4186 ENOG4105WH1 Two component transcriptional regulator luxr family BG02_4190 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BG02_4195 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BG02_4199 ENOG4105CJ3 phosphate transporter BG02_4200 ENOG4107GRR phosphate transport regulator BG02_4201 ENOG4105BZ4 penicillin-binding protein BG02_4204 ENOG4105BZU Histidine kinase BG02_4205 ENOG4105I3N Conserved Protein BG02_4208 ENOG4105BZU Histidine kinase BG02_421 ENOG4105KVH Transcriptional regulator BG02_4215 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BG02_4216 ENOG4105DZ1 carboxypeptidase BG02_4217 ENOG4108JIC nucleoside recognition domain protein BG02_4219 ENOG4105FE9 pseudouridine synthase BG02_422 ENOG4108RCM Nitroreductase BG02_4221 ENOG4107TWT Cytochrome c biogenesis protein BG02_4222 ENOG4105CRE cytochrome C BG02_4223 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_4224 ENOG4105BZU Histidine kinase BG02_4225 ENOG4108WBT adenosyltransferase BG02_4228 ENOG4108SAX Membrane BG02_4230 ENOG4105T7X BG02_4231 ENOG4105C9U ATP-dependent DNA helicase RecQ BG02_4232 ENOG4105I7S Abortive infection protein BG02_4234 ENOG4107RGJ metallophosphoesterase BG02_4235 ENOG4107X2D transcriptional regulator, merr family BG02_4236 ENOG4108S6Z Negative regulator of genetic competence BG02_4241 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BG02_4242 ENOG4107RB3 L-asparaginase BG02_4249 ENOG4105S2F BG02_4250 ENOG41065D1 BG02_4256 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BG02_4259 ENOG4105XXQ heptaprenyl diphosphate synthase component I BG02_426 ENOG4108PSK reductase BG02_4261 ENOG4105EAH synthase BG02_4265 ENOG4105CIH Imidazole acetol-phosphate transaminase BG02_4266 ENOG41068YB TPR repeat-containing protein BG02_4269 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BG02_4270 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BG02_4271 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BG02_4277 ENOG4108JYZ YitT family BG02_4278 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BG02_428 ENOG4105CJ1 ABC, transporter BG02_4281 ENOG4105FJR Lmbe family BG02_4282 ENOG4105CPK Glycosyl transferase (Group 1 BG02_4289 ENOG4105DVT helicase BG02_4290 ENOG4105YAC BG02_4294 ENOG4105CSM endonuclease III BG02_4296 ENOG4105BZ4 penicillin-binding protein BG02_43 ENOG4105EMN RNA polymerase sigma factor BG02_4307 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BG02_4309 ENOG4105DVT helicase BG02_4310 ENOG4105CTD carboxy-peptidase BG02_4313 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BG02_4315 ENOG4105C2W permease BG02_4316 ENOG4105DHF Membrane BG02_4318 ENOG410890F Dynamin family BG02_4320 ENOG4108W0I acetyltransferase BG02_4322 ENOG4105KHC sulfurtransferase BG02_4325 ENOG4106032 Glutathionylspermidine synthase BG02_4339 ENOG4105CPK Glycosyl transferase (Group 1 BG02_4342 ENOG4108SZE gCN5-related N-acetyltransferase BG02_4346 ENOG41081VK Ribonuclease BG02_4360 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG02_4362 ENOG4107RWR Sodium hydrogen exchanger BG02_4363 ENOG4105CN5 Metallo-Beta-Lactamase BG02_4364 ENOG4108Z5V transcriptional regulator, merr family BG02_4366 ENOG4105H67 Protein of unknown function (DUF421) BG02_4367 ENOG41080C8 DUF218 domain BG02_4378 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BG02_4380 ENOG4107R0U MotA TolQ exbB proton channel BG02_4381 ENOG4105ER2 Ompa motb domain protein BG02_4382 ENOG4107YTP response regulator receiver protein BG02_4383 ENOG4105CBS Chea signal transduction histidine kinase BG02_4384 ENOG4105CBS Chea signal transduction histidine kinase BG02_4385 ENOG4105DD5 Flagellar motor switch protein BG02_4388 ENOG4105BZU Histidine kinase BG02_4392 ENOG4105E1Q flagellar hook-associated protein BG02_4393 ENOG4105DTJ flagellar hook-associated protein BG02_4398 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BG02_4399 ENOG4108ZC9 flagellar basal-body rod protein flgc BG02_440 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_4400 ENOG41075Z6 flagellar hook-basal body complex protein fliE BG02_4401 ENOG4107U2N Flagellar M-ring protein BG02_4403 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BG02_441 ENOG4105DKQ ROK family BG02_4410 ENOG4105BZE flagellar hook protein, FlgE BG02_4414 ENOG4107R88 Chemotaxis protein (CheV) BG02_4416 ENOG4105K64 Glycosyl transferase, family 2 BG02_442 ENOG4106UW1 Major Facilitator superfamily BG02_4422 ENOG4107TVC Glycosyl transferase, family 2 BG02_4427 ENOG4105I03 Flagellin BG02_4428 ENOG4105E4C Lytic transglycosylase catalytic BG02_4429 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BG02_443 ENOG4108UW5 maltose o-acetyltransferase BG02_4431 ENOG4105DD5 Flagellar motor switch protein BG02_4433 ENOG4105CN7 Flagellar biosynthetic protein FliP BG02_4434 ENOG4105VS8 Flagellar biosynthetic protein fliq BG02_4436 ENOG4105D00 flagellar biosynthetic protein flhB BG02_4437 ENOG4105D7B Flagellar biosynthesis protein flha BG02_4440 ENOG4105KTQ flagellar basal-body rod protein BG02_4441 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG02_4446 ENOG4108RZE Tetr family transcriptional regulator BG02_4450 ENOG4105KAC Antibiotic biosynthesis monooxygenase BG02_4455 ENOG4105DUM transcriptional regulator, lysR family BG02_4456 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BG02_4457 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BG02_4458 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BG02_4459 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BG02_446 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BG02_4466 ENOG4105CVJ phosphoglycerate mutase BG02_4473 ENOG4105CAQ asparagine synthetase BG02_4477 ENOG4105PGM cation diffusion facilitator family transporter BG02_4479 ENOG4105DRR Transcriptional regulator, GntR family BG02_4480 ENOG4108UZ3 Transporter BG02_4481 ENOG4105CKI cobalamin synthesis protein BG02_4482 ENOG4108PJD permease BG02_4485 ENOG4105DFD Na H antiporter BG02_4486 ENOG4105C9Q fumarate hydratase class II BG02_4490 ENOG4107QJQ Mate efflux family protein BG02_4491 ENOG4107QJQ Mate efflux family protein BG02_4492 ENOG4105EC3 peptidase S51, dipeptidase E BG02_4496 ENOG4107QIV Cytochrome c biogenesis protein BG02_450 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BG02_4503 ENOG4106BRA Membrane BG02_4510 ENOG4105CJ1 ABC, transporter BG02_4514 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BG02_4516 ENOG4108IJ0 Aspartate ammonia-lyase BG02_4517 ENOG4105C6K Malic enzyme BG02_4531 ENOG4105FVX BG02_4539 ENOG4105CSR polyphosphate kinase 2 BG02_4540 ENOG4105DXI Major Facilitator superfamily BG02_4541 ENOG4105DXI Major Facilitator superfamily BG02_4544 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG02_4547 ENOG4105EU0 Major facilitator Superfamily BG02_4548 ENOG4105C6T cysteine synthase BG02_455 ENOG4105DMQ Methyltransferase BG02_4552 ENOG4105C8J )-transporter BG02_4554 ENOG4105X5K response regulator receiver protein BG02_4555 ENOG4105H67 Protein of unknown function (DUF421) BG02_4558 ENOG4106KE4 Dehydrogenase BG02_4562 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BG02_4563 ENOG4105CHR reductase BG02_4564 ENOG4105CM2 brancheD-chain amino acid aminotransferase BG02_4565 ENOG4105C7K acetolactate synthase BG02_4566 ENOG4108ZP8 Acetolactate synthase small subunit BG02_4567 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BG02_4569 ENOG4105C7B Threonine dehydratase BG02_457 ENOG4105EV4 Multidrug resistance protein mdtH BG02_4575 ENOG4105C6X Major Facilitator BG02_4576 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BG02_4578 ENOG4105DY9 regulatoR BG02_4579 ENOG4105CYC Transferase BG02_4583 ENOG4105F6J Alpha beta hydrolase fold BG02_4584 ENOG4108J59 Extracellular solute-binding protein, family 5 BG02_4590 ENOG41068WN BG02_4595 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BG02_4596 ENOG4105C72 UPF0176 protein BG02_4598 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BG02_4600 ENOG4105C0X amino acid BG02_4601 ENOG4105C0X amino acid BG02_4606 ENOG4107RHR regulatoR BG02_4608 ENOG4105D9N nucleoside BG02_4609 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BG02_4615 ENOG4107RAQ aminopeptidase BG02_4616 ENOG4107STQ Multicopper oxidase BG02_4628 ENOG4105KTB nuclear export factor GLE1 BG02_463 ENOG4105C37 (CBS) domain BG02_4630 ENOG4107RT3 EamA-like transporter family BG02_4631 ENOG4105GZI Transcriptional regulator BG02_4632 ENOG4108Z40 Transcriptional regulator BG02_4633 ENOG4107ZXU DSBA oxidoreductase BG02_4634 ENOG4108TVJ Nitroreductase BG02_4636 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BG02_4637 ENOG4106F5Q Membrane BG02_4638 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BG02_4640 ENOG4105CKI cobalamin synthesis protein BG02_4644 ENOG4108Z7G MaoC domain protein dehydratase BG02_4645 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BG02_4647 ENOG4105C0Z ABC transporter BG02_4648 ENOG4108IV0 ABC, transporter BG02_4649 ENOG4105C32 Amino acid ABC transporter (Permease) BG02_4651 ENOG4105SKE transcriptional Regulator LysR family BG02_4655 ENOG4105YGB Transcriptional regulator BG02_4657 ENOG4105C4M (Ubiquinol oxidase) subunit I BG02_4658 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BG02_4659 ENOG4108JJ9 ABC, transporter BG02_466 ENOG4105DDN Pentapeptide repeat-containing protein BG02_4660 ENOG4108JJ8 (ABC) transporter BG02_4668 ENOG4105BZ1 (ABC) transporter BG02_4669 ENOG4105BZ1 (ABC) transporter BG02_467 ENOG4105XDF Protein of unknown function (DUF1272) BG02_4670 ENOG4105EFI regulatoR BG02_4671 ENOG4105BZU Histidine kinase BG02_4674 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BG02_4675 ENOG4108ZJ4 polysaccharide deacetylase BG02_4679 ENOG4105D6E homoserine dehydrogenase BG02_468 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BG02_4684 ENOG4108KGH TRANSCRIPTIONal BG02_4686 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BG02_4687 ENOG4105BZU Histidine kinase BG02_4688 ENOG4107VMI polysaccharide deacetylase BG02_469 ENOG4105CMG Carbohydrate kinase BG02_4690 ENOG4105KT7 mgtC SapB transporter BG02_4691 ENOG4105VRR gCN5-related N-acetyltransferase BG02_4693 ENOG4105DUU IucA IucC family protein BG02_4694 ENOG4105CEY Amp-dependent synthetase and ligase BG02_4697 ENOG4108WBH protein TIM barrel BG02_4698 ENOG4105YWU small acid-soluble spore protein BG02_4699 ENOG4107RCC Major Facilitator Superfamily BG02_470 ENOG4105C6Z Gluconate BG02_4701 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BG02_471 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BG02_4712 ENOG4105KRN Transcriptional regulator, abrb family BG02_4714 ENOG4105YVS arsR family transcriptional regulator BG02_4715 ENOG4107SET aldo keto reductase BG02_4716 ENOG4107XZQ multidrug resistance protein BG02_4721 ENOG4105C8Q Methyl-accepting chemotaxis BG02_4724 ENOG4108K88 Membrane BG02_4725 ENOG4108WPJ Ferritin-like domain BG02_4728 ENOG4105DEN Luciferase family BG02_4732 ENOG4107QM2 Aldo Keto reductase BG02_4733 ENOG4105CKI cobalamin synthesis protein BG02_474 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BG02_4744 ENOG4105DSE periplasmic solute binding protein BG02_4746 ENOG4105K4T epimerase BG02_4748 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BG02_475 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BG02_4753 ENOG4105CVJ phosphoglycerate mutase BG02_4757 ENOG4107T5V SNARE associated Golgi BG02_476 ENOG4105CIS alcohol dehydrogenase BG02_4760 ENOG4108PJD permease BG02_4762 ENOG4108S4H thioesterase Superfamily protein BG02_4763 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BG02_4767 ENOG4105SXS Protein of unknown function (DUF456) BG02_4768 ENOG4105C37 (CBS) domain BG02_477 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BG02_4772 ENOG4108Z7R Chaperone CsaA BG02_4776 ENOG4108ZRV stage ii sporulation protein p BG02_4778 ENOG4108VXD carboxy-peptidase BG02_4780 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BG02_4785 ENOG4108X4Q Hydrolase BG02_4787 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BG02_4788 ENOG4107RBS Methyltransferase BG02_4791 ENOG41087PP glycosyltransferase MGT family BG02_4792 ENOG4108JYZ YitT family BG02_4793 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BG02_4799 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BG02_480 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BG02_4808 ENOG4105KBJ sporulation protein ytfj BG02_481 ENOG4105D4Y metalloprotease BG02_4813 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BG02_4817 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BG02_4818 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_4820 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BG02_4821 ENOG4105EMN RNA polymerase sigma factor BG02_4826 ENOG4108V06 Glutathione peroxidase BG02_4829 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG02_4833 ENOG4108IUE nitrate reductase beta subunit BG02_4834 ENOG4105R3A Nitrate reductase BG02_4839 ENOG4107V6Q Cyclic nucleotide-binding domain BG02_4840 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BG02_4841 ENOG4105D06 uba thif-type nad fad binding protein BG02_4842 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG02_4843 ENOG4108ZAF Molybdopterin BG02_4848 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BG02_4849 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BG02_485 ENOG4105CV8 reductase BG02_4850 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BG02_4851 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BG02_4852 ENOG4108IFG nitrite reductase, (NAD(P)H) BG02_4853 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BG02_486 ENOG4105F27 Major Facilitator BG02_4860 ENOG4105MCT stage V sporulation protein S BG02_4863 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG02_4867 ENOG4105C5H ABC transporter BG02_4870 ENOG4108UUM single-stranded DNA-binding protein BG02_4873 ENOG41061H0 Monooxygenase BG02_4877 ENOG4107YX5 Pfam:DUF548 BG02_4878 ENOG4105C75 arginyL-tRNA synthetase BG02_4884 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BG02_4887 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BG02_4888 ENOG4105C5S asparaginyl-tRNA synthetase BG02_489 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BG02_4892 ENOG4105EC2 ftsk spoIIIe BG02_49 ENOG4105D4B ABC, transporter BG02_490 ENOG4105C44 Serine transporter BG02_4911 ENOG4105BZW Glycerate kinase BG02_4912 ENOG4107QPK )-transporter BG02_4913 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_4914 ENOG41062D9 Histidine kinase BG02_4917 ENOG4105C8J )-transporter BG02_4921 ENOG4107XGZ Hydrolase BG02_4922 ENOG4105CY2 Citrate transporter BG02_4923 ENOG4105C0A alcohol dehydrogenase BG02_4926 ENOG4105KD7 acetyltransferase BG02_4928 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BG02_4933 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BG02_4937 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BG02_4940 ENOG4107RVG penicillin-binding protein BG02_4941 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BG02_4942 ENOG4105E9Q Acyl-transferase BG02_4943 ENOG4108UT2 hemolysin iii BG02_4945 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BG02_4947 ENOG4108RCR degv family BG02_4948 ENOG4105E8R UPF0173 metal-dependent hydrolase BG02_4949 ENOG4108KF3 Electron transport protein SCO1 SenC BG02_4950 ENOG4107Y70 Heat shock protein BG02_4951 ENOG4105CAQ asparagine synthetase BG02_4955 ENOG4108MES Periplasmic binding protein BG02_4956 ENOG4105F0I Aminotransferase BG02_496 ENOG4105KVH Transcriptional regulator BG02_4963 ENOG4105D8X mechanosensitive ion channel BG02_4964 ENOG4105BZU Histidine kinase BG02_4965 ENOG4105WH1 Two component transcriptional regulator luxr family BG02_4967 ENOG4106KNT transcriptional regulator BG02_497 ENOG4108TZY GntR Family Transcriptional Regulator BG02_4975 ENOG4105CMG Carbohydrate kinase BG02_4976 ENOG4105CMG Carbohydrate kinase BG02_498 ENOG4105D9R oxidoreductase BG02_4982 ENOG4108IJ8 ABC transporter BG02_4983 ENOG4105E90 ABC transporter BG02_4990 ENOG4105C37 (CBS) domain BG02_4995 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BG02_4998 ENOG4107S4Y M20 DapE family protein YgeY BG02_4999 ENOG4108TSC N-acetyltransferase BG02_500 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BG02_5000 ENOG4108JUB Transcriptional regulator BG02_5001 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BG02_5009 ENOG4108N23 SpoOM-related protein BG02_501 ENOG4105KVH Transcriptional regulator BG02_5011 ENOG410841Q phosphoesterase PA-phosphatase related protein BG02_5012 ENOG4105SZ6 Thioredoxin BG02_5014 ENOG4108IBT Inherit from COG: transposase BG02_502 ENOG4105KVH Transcriptional regulator BG02_5033 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BG02_5041 ENOG4105BZ4 penicillin-binding protein BG02_5042 ENOG4105CZM Major Facilitator BG02_5043 ENOG4105W8X HesB YadR YfhF-family protein BG02_5045 ENOG4105DXD 2-methylcitrate dehydratase BG02_5046 ENOG4105CR4 methylisocitrate lyase BG02_5047 ENOG4105C1G acyl-Coa dehydrogenase BG02_5048 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BG02_5050 ENOG4105N14 lysine exporter protein LysE YggA BG02_5051 ENOG4105E39 Enoyl-CoA hydratase BG02_5054 ENOG4107RFY SbcCD D subunit BG02_5055 ENOG4105EYH Exonuclease BG02_5059 ENOG4105FCD Major Facilitator BG02_5060 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BG02_5061 ENOG4105E4F Isochorismate synthase BG02_5062 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BG02_5063 ENOG4105WQI isochorismatase BG02_5064 ENOG4105CEY Amp-dependent synthetase and ligase BG02_5065 ENOG4105WQT MbtH domain protein BG02_5066 ENOG4105C0R drug resistance transporter emrb qaca subfamily BG02_5069 ENOG4105K70 DNA-binding protein BG02_5073 ENOG4105BZG amino acid carrier protein BG02_5077 ENOG4105FE9 pseudouridine synthase BG02_5078 ENOG4105C22 threonyL-tRNA synthetase BG02_5082 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BG02_5088 ENOG4108D32 Methyltransferase BG02_509 ENOG4105JAB phenazine biosynthesis protein, phzf family BG02_5094 ENOG41081I9 integral membrane protein BG02_5097 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BG02_5099 ENOG4105EYF MMPL domain protein BG02_51 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BG02_5104 ENOG4105WCN acetyltransferase BG02_511 ENOG4105CHR reductase BG02_5110 ENOG4105C1Q protoporphyrinogen oxidase BG02_5112 ENOG41068WN BG02_5114 ENOG4105VEQ Cold shock protein BG02_5118 ENOG410667J hydrolase BG02_5126 ENOG4107V2S Transcriptional regulator BG02_5127 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BG02_5130 ENOG4105DND Transcriptional regulator BG02_5131 ENOG4108RPX mosc domain containing protein BG02_5134 ENOG4105BZ1 (ABC) transporter BG02_5135 ENOG4105BZ1 (ABC) transporter BG02_5139 ENOG4108JCI Transcriptional regulator BG02_5144 ENOG4108KPJ rna polymerase sigma factor BG02_5149 ENOG4105F32 YngK protein BG02_515 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BG02_5154 ENOG4105RD7 BadF BadG BcrA BcrD BG02_5156 ENOG4107STF Involved in phosphonate degradation (By similarity) BG02_5159 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BG02_516 ENOG4105KVH Transcriptional regulator BG02_5162 ENOG4105C1J atp-dependent rna helicase BG02_5164 ENOG4108RZE Tetr family transcriptional regulator BG02_5168 ENOG41088CC tellurite resistance protein tehB BG02_5170 ENOG4108I0C methyltransferase BG02_5171 ENOG4107RA9 decarboxylase BG02_5172 ENOG41090HR transcriptional regulator BG02_5180 ENOG4105CIN aminoacyl-histidine dipeptidase BG02_5186 ENOG4107RF6 penicillin-binding protein BG02_5187 ENOG4107RF6 penicillin-binding protein BG02_5188 ENOG4107RF6 penicillin-binding protein BG02_5190 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BG02_5191 ENOG4105ETE Transcriptional regulator (LacI family BG02_5192 ENOG4105IE8 Alpha-ketoglutarate permease BG02_5193 ENOG4105CK5 oxidoreductase BG02_5199 ENOG4105D2N Aldolase BG02_520 ENOG4108ZJ4 polysaccharide deacetylase BG02_5200 ENOG4105DH8 myo-inositol catabolism BG02_5204 ENOG4105CGH 5'-nucleotidase BG02_5209 ENOG4105VZ8 Transcriptional regulator BG02_5212 ENOG4108VXD carboxy-peptidase BG02_5217 ENOG41067SE Tetr family transcriptional regulator BG02_5218 ENOG4105C5H ABC transporter BG02_5220 ENOG4105BZU Histidine kinase BG02_5222 ENOG4106ANW SMI1_KNR4 BG02_5223 ENOG4105CEP NADH dehydrogenase BG02_5224 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BG02_5227 ENOG4105CJ1 ABC, transporter BG02_5232 ENOG4105C1G acyl-Coa dehydrogenase BG02_5233 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BG02_5234 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BG02_5235 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BG02_5236 ENOG4105E39 Enoyl-CoA hydratase BG02_5237 ENOG4107QX3 carboxylase BG02_5238 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BG02_5240 ENOG4105WCN acetyltransferase BG02_5241 ENOG4105DBI uridine monophosphokinase BG02_5244 ENOG4105DZ1 carboxypeptidase BG02_5247 ENOG4105T9C HD domain BG02_5249 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BG02_5258 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG02_5258 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BG02_5261 ENOG4105FQP Beta-lactamase BG02_5263 ENOG4107Y80 Major Facilitator superfamily BG02_5267 ENOG4105CUV Homoserine Kinase BG02_5273 ENOG4105CPQ Dehydrogenase BG02_5276 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG02_5277 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BG02_5299 ENOG4105ETU transcriptional activator (TenA BG02_53 ENOG4105DKT Transcriptional regulator BG02_530 ENOG4105KAF membrAne BG02_5322 ENOG410667J hydrolase BG02_5324 ENOG4105BZU Histidine kinase BG02_5325 ENOG4107RF6 penicillin-binding protein BG02_5329 ENOG4108JJB ABC transporter BG02_5332 ENOG4108HGU Histidine kinase BG02_5335 ENOG4105CB2 alcohol dehydrogenase BG02_5336 ENOG4105CJN penicillin-binding protein BG02_5338 ENOG4105FQP Beta-lactamase BG02_5344 ENOG4108V4B ThiJ pfpI BG02_5349 ENOG4107Y80 Major Facilitator superfamily BG02_535 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BG02_5353 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BG02_5358 ENOG4107Y9U Membrane BG02_5365 ENOG4105FCD Major Facilitator BG02_5367 ENOG4105E09 nadh pyrophosphatase BG02_5368 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BG02_5369 ENOG4108Z4K mutator MutT protein BG02_5376 ENOG4108XI2 Domain of unknown function (DUF1963) BG02_5382 ENOG4108NRW Phospholipase, patatin family BG02_5383 ENOG4105KWG Pfam:DUF1696 BG02_539 ENOG4107YXZ hydrolase, family 25 BG02_5391 ENOG4105PKS Excinuclease abc c subunit domain protein BG02_5399 ENOG4107VFR oxidoreductase BG02_54 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BG02_5404 ENOG4105PAD Hydrolase BG02_5409 ENOG4105DY8 decarboxylase BG02_5412 ENOG4108IUM Glycogen debranching enzyme BG02_5417 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BG02_5418 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BG02_5419 ENOG4108Q5Y Membrane BG02_5426 ENOG4108V3A UPF0421 protein BG02_5430 ENOG4105MSI germination protein ypeb BG02_5434 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BG02_5435 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BG02_5436 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BG02_5437 ENOG4107Z3H Transcriptional regulator, TetR family BG02_544 ENOG4105ED2 Beta-lactamase BG02_5443 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BG02_5447 ENOG4105E98 transcriptional regulator DeoR family BG02_5451 ENOG41062ES Transcriptional regulator BG02_5456 ENOG4107QKR Dehydrogenase BG02_5458 ENOG4107RUY (E1 component), alpha subunit BG02_546 ENOG4105H3G oxidoreductase BG02_5460 ENOG4105E1F short-chain dehydrogenase reductase BG02_5461 ENOG4105RHY Pfam:UPF0157 BG02_5467 ENOG4107SQ8 Glycine betaine BG02_5468 ENOG4108IJ7 Glycine betaine BG02_5473 ENOG4105E66 phosphoriboisomerase A BG02_5474 ENOG41082BV acetyltransferase BG02_5475 ENOG4108M1A Chitin-binding protein BG02_5485 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BG02_5496 ENOG4105EEM helicase BG02_5500 ENOG4105C9U ATP-dependent DNA helicase RecQ BG02_5508 ENOG4108M1A Chitin-binding protein BG02_5511 ENOG4105BZG amino acid carrier protein BG02_5512 ENOG4105C26 Dehydrogenase BG02_5513 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BG02_5514 ENOG4105CTU Proline racemase BG02_5515 ENOG4105CTU Proline racemase BG02_5516 ENOG41080HI glycine oxidase BG02_5523 ENOG4107T5V SNARE associated Golgi BG02_5526 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BG02_5527 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BG02_553 ENOG4105CIS alcohol dehydrogenase BG02_5530 ENOG4105DTQ mandelate racemase muconate lactonizing BG02_5538 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BG02_5539 ENOG4105BZU Histidine kinase BG02_5540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_5547 ENOG4105DPN Oligoendopeptidase f BG02_5550 ENOG4105EPR degv family BG02_5558 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BG02_5559 ENOG4106K7D Major facilitator family transporter BG02_5564 ENOG4107BMA Transglycosylase associated protein BG02_5567 ENOG41089UC methyltransferase, type 11 BG02_5573 ENOG4105CHM Aminotransferase BG02_5580 ENOG4105DVE abc transporter atp-binding protein BG02_5589 ENOG4105C02 permease BG02_5591 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BG02_5592 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BG02_5593 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BG02_560 ENOG4108TN2 lmbE family BG02_5618 ENOG4105CNU cell division protein FtsK BG02_562 ENOG4107R3E Citrate transporter BG02_5633 ENOG4106JUT Streptomycin 3''-adenylyltransferase BG02_5645 ENOG4105EKQ RNA-directed DNA polymerase BG02_566 ENOG4108MES Periplasmic binding protein BG02_5667 ENOG4105EKQ RNA-directed DNA polymerase BG02_568 ENOG4105EHG Permease protein BG02_5688 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BG02_569 ENOG4105DQ5 transport system permease protein BG02_5695 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BG02_5697 ENOG4108MEK Metal-binding protein YodA BG02_5699 ENOG4105DQ6 Transposase BG02_57 ENOG41061GT Aldolase BG02_570 ENOG4105NX3 Membrane BG02_5700 ENOG4105DQ6 Transposase BG02_5703 ENOG4105DQ6 Transposase BG02_5705 ENOG4108IBT Inherit from COG: transposase BG02_571 ENOG4107ZY0 Phenazine biosynthesis-like protein BG02_5712 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BG02_5714 ENOG4105KRN Transcriptional regulator, abrb family BG02_5736 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BG02_5742 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BG02_575 ENOG4107CUJ Protein of unknown function (DUF2690) BG02_5750 ENOG4105DQ6 Transposase BG02_5751 ENOG4105DQ6 Transposase BG02_5755 ENOG4105C6Y Udp-glucose 6-dehydrogenase BG02_5756 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BG02_5760 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BG02_5761 ENOG4106AKK s-layer domain-containing protein BG02_5767 ENOG4105DHF Membrane BG02_577 ENOG4107V2S Transcriptional regulator BG02_5795 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BG02_5805 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG02_5806 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG02_581 ENOG4105C98 muts2 protein BG02_5819 ENOG4105K4H Nlp p60 protein BG02_583 ENOG4105E5K Alpha-amylase BG02_584 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BG02_585 ENOG4105DPN Oligoendopeptidase f BG02_5853 ENOG4107QJE Chromosome Partitioning Protein BG02_5858 ENOG4105DQ6 Transposase BG02_586 ENOG4108A04 Beta-lactamase BG02_5865 ENOG4105EWC Purine nucleoside phosphorylase BG02_5883 ENOG4105C3F Signal peptidase i BG02_5891 ENOG4105N14 lysine exporter protein LysE YggA BG02_5897 ENOG4108J59 Extracellular solute-binding protein, family 5 BG02_592 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BG02_596 ENOG41082BM Transcriptional regulator, arsr family BG02_597 ENOG4105CIS alcohol dehydrogenase BG02_603 ENOG4105RHY Pfam:UPF0157 BG02_605 ENOG4105C09 Bile acid BG02_606 ENOG4105CQB FAD linked oxidase domain protein BG02_610 ENOG4108UT6 Transferase hexapeptide repeat containing protein BG02_612 ENOG4105K64 Glycosyl transferase, family 2 BG02_613 ENOG4105E39 Enoyl-CoA hydratase BG02_615 ENOG4105KT7 mgtC SapB transporter BG02_617 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_618 ENOG41073R8 VanW family BG02_62 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BG02_620 ENOG4108R1P BG02_624 ENOG4105VEQ Cold shock protein BG02_628 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BG02_632 ENOG410904N short-chain dehydrogenase reductase BG02_634 ENOG4106IQC argininosuccinate lyase BG02_637 ENOG4108IA2 Sodium pantothenate symporter BG02_638 ENOG4105RG0 Membrane BG02_639 ENOG4105C26 Dehydrogenase BG02_640 ENOG4105CHR reductase BG02_641 ENOG4105EWU Squalene--hopene cyclase BG02_643 ENOG4105FR1 rard protein BG02_644 ENOG410696E Membrane BG02_647 ENOG4105D1F ATP-binding protein BG02_649 ENOG4108ZAF Molybdopterin BG02_650 ENOG4105CVM Molybdenum cofactor synthesis domain protein BG02_651 ENOG4105D06 uba thif-type nad fad binding protein BG02_652 ENOG4105TMB Formate nitrite transporter BG02_654 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BG02_655 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BG02_657 ENOG4108JB9 formate dehydrogenase BG02_659 ENOG4105E1K spore germination protein BG02_671 ENOG4107QJT sodium dicarboxylate symporter BG02_672 ENOG4108KGH TRANSCRIPTIONal BG02_674 ENOG4105EMN RNA polymerase sigma factor BG02_678 ENOG4105CIG ABC transporter BG02_68 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BG02_680 ENOG4105D9R oxidoreductase BG02_682 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BG02_683 ENOG4105K4P CoA-binding domain protein BG02_684 ENOG4105C0H protease BG02_685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BG02_687 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BG02_688 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BG02_689 ENOG4105W8X HesB YadR YfhF-family protein BG02_69 ENOG4105II7 pyrroline-5-carboxylate reductase BG02_695 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BG02_696 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BG02_698 ENOG4108JJA ABC, transporter BG02_699 ENOG4108I0Z Aconitate hydratase BG02_7 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BG02_704 ENOG4105E5W Transporter BG02_706 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BG02_71 ENOG4107258 Transcriptional regulator BG02_710 ENOG4107F3J Amp-dependent synthetase and ligase BG02_711 ENOG4107ZYJ bioY protein BG02_712 ENOG4105CEY Amp-dependent synthetase and ligase BG02_721 ENOG4107AYK membrAne BG02_723 ENOG4105BZU Histidine kinase BG02_724 ENOG4105FBA Phospholipase Carboxylesterase BG02_725 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BG02_726 ENOG4105CK7 Sodium proline symporter BG02_727 ENOG4105CBC glutamate synthase BG02_728 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BG02_729 ENOG4108VJ1 Transcriptional regulator (CarD family BG02_73 ENOG4105E0Y RtcB Protein BG02_730 ENOG4108903 Formimidoylglutamase BG02_735 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BG02_74 ENOG4105ECK Fatty Acid Desaturase BG02_746 ENOG4107QIV Cytochrome c biogenesis protein BG02_748 ENOG4107RSM transcriptional regulator BG02_749 ENOG4105VAW lrga family BG02_75 ENOG4105G6Z alkaline phosphatase BG02_750 ENOG41067MG lrgb family BG02_755 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BG02_758 ENOG4105BZ1 (ABC) transporter BG02_759 ENOG4105BZ1 (ABC) transporter BG02_763 ENOG4105D7V transposase BG02_766 ENOG4105D5T phosphonate abc transporter BG02_769 ENOG4105CGH 5'-nucleotidase BG02_77 ENOG4105VMP Transcriptional regulator BG02_771 ENOG4108SVB resolvase BG02_775 ENOG4105K7K Transcriptional regulator BG02_783 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BG02_784 ENOG4105XSJ toxin secretion phage lysis holin BG02_80 ENOG41090T1 Membrane BG02_82 ENOG4108WCX response regulator BG02_824 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BG02_84 ENOG41068WN BG02_845 ENOG4105C5F glutamine synthetase BG02_846 ENOG4105KV4 Transcriptional regulator BG02_847 ENOG4105CXI aluminum resistance protein BG02_848 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG02_849 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BG02_850 ENOG4105EN6 Membrane BG02_851 ENOG4106F1P AAA ATPase, central domain protein BG02_858 ENOG41069ER domain protein BG02_859 ENOG4105DM4 PTS System BG02_860 ENOG4105DE4 1-phosphofructokinase BG02_861 ENOG4105E98 transcriptional regulator DeoR family BG02_862 ENOG4107QW4 alcohol dehydrogenase BG02_863 ENOG4107QW4 alcohol dehydrogenase BG02_864 ENOG4108SJC Membrane BG02_867 ENOG4105C85 amino acid BG02_871 ENOG4105TMB Formate nitrite transporter BG02_872 ENOG4105K70 DNA-binding protein BG02_873 ENOG4105C59 p-type ATPase BG02_874 ENOG410681U heavy metal transport detoxification protein BG02_875 ENOG4105VPX protein, conserved in bacteria BG02_877 ENOG4105NIV Esterase BG02_878 ENOG4105E0A ABC, transporter BG02_883 ENOG4105CGK Exodeoxyribonuclease III BG02_885 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BG02_886 ENOG4105D03 DNA-3-methyladenine glycosylase II BG02_89 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BG02_892 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BG02_893 ENOG4105BZU Histidine kinase BG02_896 ENOG41067MG lrgb family BG02_899 ENOG4107TTQ Alpha beta hydrolase fold BG02_900 ENOG4107YEI lmbE family BG02_904 ENOG4105F0V Cell wall hydrolase BG02_905 ENOG4107R6R udp-galactopyranose mutase BG02_906 ENOG4105E0M Sulfatase BG02_907 ENOG410890F Dynamin family BG02_909 ENOG4107QHE Choloylglycine hydrolase BG02_914 ENOG4105DA5 (ABC) transporter BG02_919 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BG02_920 ENOG4105DQU oxidoreductase, subunit beta BG02_921 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BG02_922 ENOG4108IGT Dipeptidase BG02_923 ENOG4105MCT stage V sporulation protein S BG02_924 ENOG4105D48 metallophosphoesterase BG02_929 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BG02_932 ENOG4105XZV Protein of unknown function (DUF3243) BG02_933 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BG02_937 ENOG4105UIB (ABC) transporter BG02_938 ENOG4105UIB (ABC) transporter BG02_939 ENOG4108JQ9 ABC transporter BG02_94 ENOG4105CKK Glycosyl transferase, family 2 BG02_940 ENOG4105DIH basic membrane BG02_941 ENOG4105FDP GntR family transcriptional regulator BG02_942 ENOG4107QZI cell division protein FtsK BG02_944 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BG02_946 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BG02_948 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BG02_949 ENOG4108S0H Dipicolinic acid synthetase, b subunit BG02_950 ENOG4105E35 Dipicolinate synthase subunit A BG02_952 ENOG4105C1V Peptidase, M16 BG02_956 ENOG4105DTN riboflavin biosynthesis protein ribF BG02_957 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BG02_959 ENOG4105W7A Protein of unknown function (DUF503) BG02_961 ENOG4105VHM ribosomal protein BG02_962 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BG02_963 ENOG4105CHV Transcription elongation factor NusA BG02_965 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BG02_967 ENOG4105DZP Membrane-associated zinc metalloprotease BG02_968 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BG02_969 ENOG4105KNE Phosphatidate cytidylyltransferase BG02_970 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BG02_978 ENOG4108HE4 integrase family BG02_980 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BG02_982 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BG02_985 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BG02_99 ENOG4105CKK Glycosyl transferase, family 2 BG02_990 ENOG4105VB6 UPF0109 protein BG02_994 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BG02_995 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BG02_998 ENOG4105CHR reductase BG02_999 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase