locus-tag	class	description
BD64_1	COG0305	Participates in initiation and elongation during chromosome replication
BD64_10	COG4853	Protein conserved in bacteria
BD64_100	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_1001	COG1587	Uroporphyrinogen-III synthase
BD64_1002	COG0113	porphobilinogen synthase activity
BD64_1004	COG1388	LysM domain
BD64_1006	COG0525	valine-tRNA ligase activity
BD64_1007	COG0285	dihydrofolate synthase activity
BD64_101	COG0789	Transcriptional regulator
BD64_1011	COG1077	Cell shape determining protein MreB Mrl
BD64_1012	COG1792	Involved in formation and maintenance of cell shape
BD64_1015	COG2894	cell division
BD64_1016	COG0739	heme binding
BD64_1017	COG1994	Peptidase M50
BD64_1018	COG1530	ribonuclease E activity
BD64_102	COG2814	Major facilitator Superfamily
BD64_1020	COG2868	ribosomal protein
BD64_1022	COG3290	protein histidine kinase activity
BD64_1023	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD64_1024	COG0745	RESPONSE REGULATOR receiver
BD64_1026	COG5002	protein histidine kinase activity
BD64_1027	COG1136	(ABC) transporter
BD64_1028	COG0577	efflux transmembrane transporter activity
BD64_1029	COG0577	efflux transmembrane transporter activity
BD64_103	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BD64_1030	COG0077	Prephenate dehydratase
BD64_1031	COG2258	MOSC domain
BD64_1032	COG1827	regulation of RNA biosynthetic process
BD64_1033	COG1104	cysteine desulfurase activity
BD64_1034	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BD64_1035	COG0157	Belongs to the NadC ModD family
BD64_104	COG0010	Belongs to the arginase family
BD64_1040	COG0640	Transcriptional regulator
BD64_1041	COG0697	spore germination
BD64_1042	COG0697	spore germination
BD64_1044	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BD64_1050	COG1862	Preprotein translocase
BD64_1052	COG2323	membrane
BD64_1053	COG2244	polysaccharide biosynthetic process
BD64_1055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BD64_1055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BD64_1056	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BD64_1057	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BD64_1057	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BD64_1059	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BD64_1062	COG0124	histidyl-tRNA synthetase
BD64_1064	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BD64_1066	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BD64_1067	COG1959	2 iron, 2 sulfur cluster binding
BD64_1068	COG1104	cysteine desulfurase activity
BD64_1069	COG0482	sulfurtransferase activity
BD64_107	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_1071	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BD64_1075	COG0628	permease
BD64_1077	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_108	COG4506	Protein conserved in bacteria
BD64_1081	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BD64_1087	COG0768	penicillin binding
BD64_109	COG0018	arginyl-trna synthetase
BD64_1092	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_1093	COG0626	cystathionine gamma-synthase activity
BD64_1094	COG1012	belongs to the aldehyde dehydrogenase family
BD64_1094	COG1454	alcohol dehydrogenase
BD64_1096	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_11	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BD64_110	COG1595	DNA-templated transcription, initiation
BD64_1104	COG2259	Doxx family
BD64_1105	COG2514	catechol 2,3-dioxygenase activity
BD64_1106	COG2514	catechol 2,3-dioxygenase activity
BD64_1108	COG3186	Phenylalanine-4-hydroxylase
BD64_1109	COG1404	Belongs to the peptidase S8 family
BD64_1116	COG2267	carboxylic ester hydrolase activity
BD64_1118	COG1785	Belongs to the alkaline phosphatase family
BD64_1120	COG2357	RelA SpoT domain protein
BD64_1121	COG0778	Nitroreductase
BD64_1123	COG1595	DNA-templated transcription, initiation
BD64_1126	COG1191	sigma factor activity
BD64_1128	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BD64_1129	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BD64_1131	COG1534	Rna-binding protein
BD64_1133	COG1713	HD superfamily hydrolase involved in NAD metabolism
BD64_1134	COG0799	negative regulation of ribosome biogenesis
BD64_1135	COG2226	methyltransferase
BD64_1136	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_1137	COG1596	polysaccharide export
BD64_1137	COG1555	photosystem II stabilization
BD64_1138	COG2131	deaminase
BD64_1139	COG0658	competence protein
BD64_1139	COG2333	competence protein COMEC
BD64_114	COG2234	aminopeptidase activity
BD64_1141	COG1466	dna polymerase III delta subunit
BD64_1146	COG1733	regulation of RNA biosynthetic process
BD64_1147	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BD64_1149	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BD64_1153	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BD64_1154	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD64_1156	COG1610	YqeY-like protein
BD64_1159	COG1702	phosphate starvation-inducible protein PhoH
BD64_1160	COG1480	7TM receptor with intracellular HD hydrolase
BD64_1162	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BD64_1163	COG0295	cytidine deaminase activity
BD64_1164	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BD64_1167	COG0517	IMP dehydrogenase activity
BD64_1169	COG0358	DNA primase activity
BD64_1170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BD64_1171	COG2010	Cytochrome c
BD64_1172	COG2384	SAM-dependent methyltransferase
BD64_1173	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BD64_1179	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_118	COG0024	Methionine aminopeptidase
BD64_1180	COG1121	(ABC) transporter
BD64_1181	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BD64_1182	COG0735	belongs to the Fur family
BD64_1187	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_1188	COG0477	Major facilitator Superfamily
BD64_119	COG1131	(ABC) transporter
BD64_1190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BD64_1191	COG0573	inorganic phosphate transmembrane transporter activity
BD64_1192	COG0581	inorganic phosphate transmembrane transporter activity
BD64_1193	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BD64_1194	COG0704	Plays a role in the regulation of phosphate uptake
BD64_1195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BD64_1197	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BD64_1198	COG4483	Protein conserved in bacteria
BD64_1199	COG1940	carbohydrate kinase activity
BD64_12	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_120	COG0842	Transport permease protein
BD64_1201	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_1205	COG0626	cystathionine gamma-synthase activity
BD64_1206	COG0626	cystathionine gamma-synthase activity
BD64_1207	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BD64_1207	COG0646	methionine synthase
BD64_1208	COG0646	methionine synthase
BD64_1208	COG1410	methionine synthase
BD64_1209	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BD64_121	COG4585	Histidine kinase
BD64_1218	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BD64_1219	COG1459	type II secretion system
BD64_122	COG2197	response regulator
BD64_1221	COG4970	Tfp pilus assembly protein FimT
BD64_1232	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_1238	COG1725	Transcriptional regulator
BD64_1239	COG1131	(ABC) transporter
BD64_1246	COG2076	Multidrug Resistance protein
BD64_1247	COG2076	Multidrug Resistance protein
BD64_1249	COG1609	Transcriptional regulator
BD64_1250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_1251	COG0095	Lipoate-protein ligase
BD64_1256	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BD64_1257	COG3872	metal-dependent enzyme
BD64_126	COG5001	Diguanylate cyclase
BD64_126	COG3300	MHYT domain
BD64_1260	COG0006	proline dipeptidase activity
BD64_1265	COG3854	ATPases associated with a variety of cellular activities
BD64_1274	COG0511	ligase activity, forming carbon-carbon bonds
BD64_1275	COG0439	Biotin carboxylase
BD64_1276	COG1302	Protein conserved in bacteria
BD64_128	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_1281	COG0142	geranyltranstransferase activity
BD64_1283	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BD64_1285	COG0497	DNA recombination
BD64_1286	COG0750	zinc metalloprotease
BD64_1287	COG0745	RESPONSE REGULATOR receiver
BD64_1289	COG3093	addiction module antidote protein HigA
BD64_129	COG0247	lactate metabolic process
BD64_129	COG2181	nitrate reductase activity
BD64_1290	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_1292	COG3290	protein histidine kinase activity
BD64_1292	COG3829	transcription factor binding
BD64_1293	COG0280	phosphate acetyltransferase
BD64_1294	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BD64_1296	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BD64_1297	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_1298	COG0022	dehydrogenase e1 component
BD64_1299	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_130	COG0183	Belongs to the thiolase family
BD64_1300	COG0772	Belongs to the SEDS family
BD64_1301	COG2816	NAD+ diphosphatase activity
BD64_1304	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_1305	COG0765	amino acid transport
BD64_1306	COG1126	abc transporter atp-binding protein
BD64_1307	COG4129	membrane
BD64_1308	COG1376	ErfK ybiS ycfS ynhG family protein
BD64_131	COG1250	3-hydroxyacyl-CoA dehydrogenase
BD64_1310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_1311	COG2195	Cleaves the N-terminal amino acid of tripeptides
BD64_1313	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BD64_1316	COG1760	l-serine dehydratase
BD64_1317	COG1760	l-serine dehydratase
BD64_1318	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_132	COG1960	acyl-CoA dehydrogenase activity
BD64_1320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_1321	COG0300	oxidoreductase activity
BD64_1324	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BD64_1326	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BD64_133	COG1960	acyl-CoA dehydrogenase activity
BD64_1330	COG1522	sequence-specific DNA binding
BD64_1332	COG0737	Belongs to the 5'-nucleotidase family
BD64_1335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_1337	COG0156	8-amino-7-oxononanoate synthase activity
BD64_1338	COG2226	methyltransferase
BD64_1338	COG1073	alpha beta
BD64_1339	COG4106	trans-aconitate 2-methyltransferase activity
BD64_1340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BD64_1344	COG0307	riboflavin synthase, alpha
BD64_1345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD64_1345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD64_1348	COG1073	alpha beta
BD64_1349	COG0456	acetyltransferase
BD64_135	COG3343	RNA polymerase activity
BD64_1352	COG2056	Na+-H+ antiporter family
BD64_1353	COG0596	Alpha beta hydrolase
BD64_1355	COG1525	nuclease
BD64_1355	COG4085	toxin activity
BD64_1355	COG0737	Belongs to the 5'-nucleotidase family
BD64_1357	COG0456	acetyltransferase
BD64_1357	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_1358	COG0656	L-ascorbic acid biosynthetic process
BD64_1359	COG0667	Aldo Keto reductase
BD64_1363	COG1300	Membrane
BD64_1364	COG0735	belongs to the Fur family
BD64_1366	COG4974	Belongs to the 'phage' integrase family
BD64_137	COG4821	SIS domain
BD64_1371	COG0598	Magnesium transport protein CorA
BD64_1374	COG1846	Transcriptional regulator
BD64_1377	COG1131	(ABC) transporter
BD64_1378	COG1725	Transcriptional regulator
BD64_1379	COG1686	Belongs to the peptidase S11 family
BD64_1383	COG0733	neurotransmitter:sodium symporter activity
BD64_1388	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_1391	COG0697	spore germination
BD64_1392	COG0561	phosphatase activity
BD64_1393	COG4086	secreted protein
BD64_1394	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BD64_1395	COG0456	acetyltransferase
BD64_1396	COG1547	Domain of unknown function (DUF309)
BD64_140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BD64_1401	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BD64_1405	COG3711	transcriptional antiterminator
BD64_1406	COG2190	(PTS) system
BD64_1406	COG1263	PTS System
BD64_1406	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_141	COG1494	fructose-1,6-bisphosphatase
BD64_1411	COG0778	Nitroreductase
BD64_1412	COG3706	GGDEF domain
BD64_1413	COG2084	Dehydrogenase
BD64_1414	COG2084	Dehydrogenase
BD64_1417	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BD64_142	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BD64_1421	COG0436	Aminotransferase
BD64_1422	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BD64_1426	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_1427	COG1695	Transcriptional regulator
BD64_1434	COG0183	Belongs to the thiolase family
BD64_1442	COG3842	ATPase activity
BD64_1443	COG0366	Alpha amylase catalytic
BD64_1445	COG2182	Extracellular solute-binding protein
BD64_1446	COG1175	transmembrane transport
BD64_1447	COG3833	ABC-type maltose transport systems, permease component
BD64_1448	COG1609	Transcriptional regulator
BD64_1449	COG0436	Aminotransferase
BD64_145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BD64_1451	COG2205	protein histidine kinase activity
BD64_1453	COG3209	COG3209 Rhs family protein
BD64_1457	COG2814	Major facilitator Superfamily
BD64_146	COG2890	protein-(glutamine-N5) methyltransferase activity
BD64_1464	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BD64_1466	COG1408	metallophosphoesterase
BD64_1467	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_1468	COG2200	EAL domain
BD64_1471	COG4703	Protein of unknown function (DUF1797)
BD64_1473	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BD64_1475	COG0517	IMP dehydrogenase activity
BD64_1476	COG0583	DNA-binding transcription factor activity
BD64_1480	COG0569	domain protein
BD64_1481	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_1483	COG0561	phosphatase activity
BD64_1484	COG0242	peptide deformylase activity
BD64_1486	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_1487	COG0022	dehydrogenase e1 component
BD64_1488	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_149	COG0009	L-threonylcarbamoyladenylate synthase
BD64_1497	COG1982	Orn Lys Arg decarboxylase major
BD64_1501	COG0483	inositol monophosphate 1-phosphatase activity
BD64_1506	COG4896	Protein conserved in bacteria
BD64_1508	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BD64_1509	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BD64_1510	COG4838	Belongs to the UPF0358 family
BD64_1511	COG0772	Belongs to the SEDS family
BD64_1512	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BD64_1519	COG3336	cytochrome c oxidase
BD64_152	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BD64_1522	COG2340	Cysteine-rich secretory protein family
BD64_1525	COG0406	alpha-ribazole phosphatase activity
BD64_1526	COG3679	Belongs to the UPF0342 family
BD64_153	COG2259	Doxx family
BD64_1530	COG0742	ribosomal rna small subunit methyltransferase
BD64_1531	COG3314	Sporulation integral membrane protein YlbJ
BD64_1533	COG1752	Esterase of the alpha-beta hydrolase superfamily
BD64_1534	COG3480	Lon protease (S16) C-terminal proteolytic domain
BD64_1536	COG0582	viral genome integration into host DNA
BD64_154	COG2190	(PTS) system
BD64_1540	COG1396	sequence-specific DNA binding
BD64_1544	COG1396	sequence-specific DNA binding
BD64_1550	COG1484	DNA-dependent DNA replication
BD64_1555	COG1191	sigma factor activity
BD64_156	COG0698	ribose 5-phosphate isomerase
BD64_1570	COG0582	viral genome integration into host DNA
BD64_1575	COG4626	Terminase
BD64_1575	COG1802	Transcriptional regulator
BD64_1594	COG4824	toxin secretion phage lysis holin
BD64_16	COG1164	Oligoendopeptidase f
BD64_1604	COG1399	metal-binding, possibly nucleic acid-binding protein
BD64_1608	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BD64_1611	COG4839	cell division protein FtsL
BD64_1613	COG0768	penicillin binding
BD64_1614	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_1617	COG0772	Belongs to the SEDS family
BD64_1618	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BD64_1619	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BD64_162	COG0356	it plays a direct role in the translocation of protons across the membrane
BD64_1620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BD64_1621	COG0849	cell division
BD64_1622	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BD64_1624	COG1191	sigma factor activity
BD64_1625	COG1191	sigma factor activity
BD64_1626	COG1873	PFAM PRC-barrel domain
BD64_1628	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BD64_1630	COG0762	integral membrane protein
BD64_1631	COG2302	S4 RNA-binding domain
BD64_1632	COG3599	regulation of cell shape
BD64_1633	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BD64_1636	COG0564	pseudouridine synthase activity
BD64_1641	COG0505	Belongs to the CarA family
BD64_1649	COG3069	C4-dicarboxylate transmembrane transporter activity
BD64_1652	COG0006	proline dipeptidase activity
BD64_1654	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BD64_1655	COG1561	YicC-like family, N-terminal region
BD64_1657	COG0194	GDP metabolic process
BD64_1659	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BD64_1660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BD64_1661	COG0242	peptide deformylase activity
BD64_1663	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BD64_1663	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BD64_1665	COG0631	protein serine/threonine phosphatase activity
BD64_1666	COG0515	serine threonine protein kinase
BD64_1666	COG2815	serine threonine protein kinase
BD64_1667	COG1162	GTPase activity
BD64_1668	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BD64_1669	COG1564	THIamine pyrophosphokinase
BD64_1671	COG1302	Protein conserved in bacteria
BD64_1672	COG1461	Dihydroxyacetone kinase
BD64_1673	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BD64_1676	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BD64_1677	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_1680	COG1196	nuclear chromosome segregation
BD64_1681	COG0552	protein localization to endoplasmic reticulum
BD64_1683	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BD64_1685	COG1837	Belongs to the UPF0109 family
BD64_1693	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BD64_1695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BD64_1697	COG4974	Belongs to the 'phage' integrase family
BD64_17	COG0516	GMP reductase activity
BD64_1703	COG0528	UMP kinase activity
BD64_1705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BD64_1706	COG4589	Belongs to the CDS family
BD64_1707	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BD64_1708	COG0750	zinc metalloprotease
BD64_1712	COG0195	Participates in both transcription termination and antitermination
BD64_1713	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BD64_1714	COG1358	cellular component organization or biogenesis
BD64_1716	COG1550	Protein conserved in bacteria
BD64_1718	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BD64_1719	COG0196	riboflavin kinase activity
BD64_172	COG3300	MHYT domain
BD64_172	COG5001	Diguanylate cyclase
BD64_1722	COG0726	polysaccharide deacetylase
BD64_1723	COG0612	Peptidase, M16
BD64_1724	COG1873	PFAM PRC-barrel domain
BD64_1725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD64_1726	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BD64_1727	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BD64_1728	COG0527	aspartate kinase activity
BD64_173	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD64_1730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_1731	COG0740	serine-type endopeptidase activity
BD64_1733	COG1674	ftsk spoiiie
BD64_1734	COG2188	Transcriptional regulator
BD64_1740	COG0612	Peptidase, M16
BD64_1741	COG0612	Peptidase, M16
BD64_1742	COG0300	oxidoreductase activity
BD64_1745	COG1426	Protein conserved in bacteria
BD64_1746	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BD64_175	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD64_1751	COG1692	metallophosphoesterase
BD64_1752	COG2359	stage V sporulation protein S
BD64_1754	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD64_1754	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BD64_1755	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD64_1756	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD64_1757	COG4550	Control of competence regulator ComK, YlbF/YmcA
BD64_176	COG0649	NAD binding
BD64_1766	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BD64_1768	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_1769	COG1368	sulfuric ester hydrolase activity
BD64_1770	COG0562	UDP-galactopyranose mutase
BD64_1771	COG3773	Cell wall hydrolase
BD64_1772	COG1404	Belongs to the peptidase S8 family
BD64_1775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_1776	COG0596	Alpha beta hydrolase
BD64_1776	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_1777	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_1778	COG1380	Effector of murein hydrolase LrgA
BD64_1779	COG1346	cytolysis
BD64_1782	COG5001	Diguanylate cyclase
BD64_1782	COG3300	MHYT domain
BD64_1783	COG0346	lactoylglutathione lyase activity
BD64_1784	COG2267	carboxylic ester hydrolase activity
BD64_1787	COG2364	Membrane
BD64_1789	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BD64_179	COG0839	Belongs to the complex I subunit 6 family
BD64_1790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BD64_1791	COG2169	Transcriptional regulator
BD64_1792	COG0708	Exodeoxyribonuclease III
BD64_1794	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_1795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_1796	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_1797	COG1120	ATPase activity
BD64_1798	COG2819	hydrolase of the alpha beta superfamily
BD64_1800	COG1937	Protein conserved in bacteria
BD64_1801	COG2608	mercury ion transmembrane transporter activity
BD64_1802	COG2217	Heavy metal translocating P-type atpase
BD64_1804	COG2116	formate transmembrane transporter activity
BD64_1805	COG1408	metallophosphoesterase
BD64_1808	COG1113	amino acid transport
BD64_181	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD64_1811	COG2322	membrane
BD64_1812	COG1979	alcohol dehydrogenase
BD64_1813	COG1979	alcohol dehydrogenase
BD64_1814	COG1349	DNA-binding transcription factor activity
BD64_1815	COG1105	Belongs to the carbohydrate kinase PfkB family
BD64_1816	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BD64_1816	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BD64_1816	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_1817	COG1388	LysM domain
BD64_1817	COG3584	3D domain protein
BD64_182	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD64_1824	COG0464	growth
BD64_1825	COG2860	membrane
BD64_1826	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BD64_1827	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BD64_1828	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BD64_1829	COG0789	Transcriptional regulator
BD64_183	COG1007	ATP synthesis coupled electron transport
BD64_1830	COG0174	glutamine synthetase
BD64_1835	COG1396	sequence-specific DNA binding
BD64_184	COG4836	Membrane
BD64_1854	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BD64_186	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BD64_1862	COG1595	DNA-templated transcription, initiation
BD64_187	COG2385	sporulation resulting in formation of a cellular spore
BD64_188	COG4555	ABC transporter
BD64_189	COG3279	Response regulator of the LytR AlgR family
BD64_1895	COG4824	toxin secretion phage lysis holin
BD64_1896	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_1896	COG3409	Peptidoglycan-binding domain 1 protein
BD64_1896	COG1388	LysM domain
BD64_1904	COG1695	Transcriptional regulator
BD64_1908	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BD64_1910	COG0737	Belongs to the 5'-nucleotidase family
BD64_1913	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BD64_1914	COG3639	organic phosphonate transmembrane transporter activity
BD64_192	COG0739	heme binding
BD64_1920	COG1132	(ABC) transporter
BD64_1921	COG1132	(ABC) transporter
BD64_1924	COG3409	Peptidoglycan-binding domain 1 protein
BD64_1924	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_1926	COG0730	response to heat
BD64_1929	COG1346	cytolysis
BD64_1930	COG1380	Effector of murein hydrolase LrgA
BD64_1931	COG0583	DNA-binding transcription factor activity
BD64_1933	COG0785	Cytochrome C biogenesis protein
BD64_1934	COG4846	Membrane protein involved in cytochrome C biogenesis
BD64_194	COG1609	Transcriptional regulator
BD64_1944	COG2226	methyltransferase
BD64_1949	COG0010	Belongs to the arginase family
BD64_1950	COG1329	Transcriptional regulator
BD64_1951	COG1902	pentaerythritol trinitrate reductase activity
BD64_1952	COG0069	glutamate synthase activity
BD64_1953	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_1954	COG0346	lactoylglutathione lyase activity
BD64_1955	COG0400	carboxylic ester hydrolase activity
BD64_1956	COG5002	protein histidine kinase activity
BD64_1958	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_1967	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_1968	COG1268	BioY protein
BD64_1969	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_1970	COG0183	Belongs to the thiolase family
BD64_1973	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_1975	COG2211	Major facilitator Superfamily
BD64_1978	COG0726	polysaccharide deacetylase
BD64_1980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BD64_1981	COG2274	protein secretion by the type I secretion system
BD64_1983	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_1989	COG0824	Thioesterase
BD64_1990	COG4841	protein insertion into membrane
BD64_1991	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_1994	COG0745	RESPONSE REGULATOR receiver
BD64_1995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_1996	COG1832	CoA-binding protein
BD64_1997	COG0187	DNA topoisomerase II activity
BD64_1998	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BD64_1999	COG0673	inositol 2-dehydrogenase activity
BD64_2001	COG1131	(ABC) transporter
BD64_2005	COG1595	DNA-templated transcription, initiation
BD64_2007	COG1316	TRANSCRIPTIONal
BD64_2008	COG1301	dicarboxylic acid transport
BD64_2009	COG4166	transmembrane transport
BD64_2010	COG4166	transmembrane transport
BD64_2011	COG4166	transmembrane transport
BD64_2012	COG2226	methyltransferase
BD64_202	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BD64_2020	COG0697	spore germination
BD64_2022	COG3383	formate dehydrogenase (NAD+) activity
BD64_2023	COG3383	formate dehydrogenase (NAD+) activity
BD64_2024	COG2427	Protein of unknown function (DUF1641)
BD64_2025	COG5609	conserved protein (DUF2294)
BD64_2026	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BD64_2028	COG2116	formate transmembrane transporter activity
BD64_2029	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_203	COG1682	transport, permease protein
BD64_2030	COG0303	'Molybdopterin
BD64_2031	COG0314	molybdopterin synthase activity
BD64_2033	COG0489	protein tyrosine kinase activity
BD64_2036	COG3326	Membrane
BD64_2037	COG2962	Rard protein
BD64_2038	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BD64_2039	COG1657	PFAM Prenyltransferase squalene oxidase
BD64_204	COG1134	teichoic acid transport
BD64_2041	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_2042	COG1012	belongs to the aldehyde dehydrogenase family
BD64_2044	COG4145	pantothenate transmembrane transporter activity
BD64_2047	COG0165	Argininosuccinate lyase
BD64_2049	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BD64_2055	COG0716	FMN binding
BD64_2057	COG1278	Cold shock
BD64_2063	COG2720	vancomycin resistance protein
BD64_2064	COG2514	catechol 2,3-dioxygenase activity
BD64_2066	COG1285	pathogenesis
BD64_2068	COG1024	Enoyl-CoA hydratase
BD64_2069	COG1216	Glycosyl transferase, family 2
BD64_2075	COG0277	FAD linked oxidase domain protein
BD64_2076	COG0385	Bile acid
BD64_2078	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_2079	COG2808	Putative FMN-binding domain
BD64_208	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BD64_2082	COG0457	Tetratricopeptide repeat
BD64_2084	COG0604	alcohol dehydrogenase
BD64_2085	COG0640	Transcriptional regulator
BD64_2089	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_209	COG0745	RESPONSE REGULATOR receiver
BD64_2095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_2098	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BD64_21	COG1272	protein, Hemolysin III
BD64_210	COG5002	protein histidine kinase activity
BD64_2101	COG1193	negative regulation of DNA recombination
BD64_2105	COG0583	DNA-binding transcription factor activity
BD64_2111	COG0384	phenazine biosynthesis protein PhzF
BD64_2112	COG3739	integral membrane protein
BD64_2113	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_2114	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_2116	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_2120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_2121	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_2127	COG2814	Major facilitator Superfamily
BD64_2128	COG1113	amino acid transport
BD64_2129	COG0604	alcohol dehydrogenase
BD64_2136	COG2072	flavoprotein involved in K transport
BD64_2143	COG3757	hydrolase, family 25
BD64_2143	COG3409	Peptidoglycan-binding domain 1 protein
BD64_2144	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_2147	COG1151	hydroxylamine reductase activity
BD64_2152	COG3152	Membrane
BD64_2156	COG1309	transcriptional regulator
BD64_2159	COG1191	sigma factor activity
BD64_2162	COG0726	polysaccharide deacetylase
BD64_2166	COG1733	regulation of RNA biosynthetic process
BD64_2167	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_2169	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_217	COG1136	(ABC) transporter
BD64_2171	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_2173	COG0384	phenazine biosynthesis protein PhzF
BD64_2177	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_218	COG0577	efflux transmembrane transporter activity
BD64_2180	COG1733	regulation of RNA biosynthetic process
BD64_2181	COG1733	regulation of RNA biosynthetic process
BD64_2182	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BD64_2184	COG0673	inositol 2-dehydrogenase activity
BD64_2185	COG2188	Transcriptional regulator
BD64_2186	COG1733	regulation of RNA biosynthetic process
BD64_2187	COG1393	Belongs to the ArsC family
BD64_2192	COG0814	amino acid
BD64_2193	COG0346	lactoylglutathione lyase activity
BD64_2196	COG2814	Major facilitator Superfamily
BD64_2197	COG0656	L-ascorbic acid biosynthetic process
BD64_22	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BD64_220	COG1191	sigma factor activity
BD64_2202	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_2205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_2206	COG0604	alcohol dehydrogenase
BD64_2207	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BD64_2208	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BD64_2210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BD64_2211	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BD64_2213	COG1070	Carbohydrate kinase
BD64_2214	COG2706	6-phosphogluconolactonase activity
BD64_2215	COG3813	Protein conserved in bacteria
BD64_2216	COG1357	PFAM Pentapeptide repeats (8 copies)
BD64_2217	COG0697	spore germination
BD64_2218	COG0789	Transcriptional regulator
BD64_2219	COG1253	flavin adenine dinucleotide binding
BD64_2225	COG0477	Major facilitator Superfamily
BD64_2227	COG2226	methyltransferase
BD64_2231	COG0628	permease
BD64_2232	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BD64_2233	COG0180	Tryptophanyl-tRNA synthetase
BD64_2235	COG1136	(ABC) transporter
BD64_2237	COG0110	maltose O-acetyltransferase activity
BD64_2238	COG0738	Major facilitator superfamily
BD64_2239	COG1940	carbohydrate kinase activity
BD64_2240	COG0346	lactoylglutathione lyase activity
BD64_2247	COG1011	Hydrolase
BD64_2252	COG1131	(ABC) transporter
BD64_2254	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_2258	COG0778	Nitroreductase
BD64_2259	COG1733	regulation of RNA biosynthetic process
BD64_226	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_2262	COG0124	histidyl-tRNA synthetase
BD64_2263	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BD64_2264	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_2265	COG3620	sequence-specific DNA binding
BD64_2268	COG2356	endonuclease I
BD64_2269	COG1288	antiporter activity
BD64_227	COG4715	Zinc finger, swim domain protein
BD64_2270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BD64_2273	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD64_2274	COG1122	ATPase activity
BD64_2280	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_2282	COG2031	fatty acid transporter
BD64_2284	COG1309	transcriptional regulator
BD64_2285	COG2076	Multidrug Resistance protein
BD64_2289	COG1131	(ABC) transporter
BD64_2290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_2293	COG2814	Major facilitator Superfamily
BD64_2294	COG1846	Transcriptional regulator
BD64_2296	COG0477	Major facilitator Superfamily
BD64_2307	COG2207	Transcriptional regulator
BD64_2307	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_2308	COG0662	Cupin 2, conserved barrel domain protein
BD64_2311	COG1595	DNA-templated transcription, initiation
BD64_2315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BD64_2318	COG0531	amino acid
BD64_2319	COG1522	sequence-specific DNA binding
BD64_232	COG1388	LysM domain
BD64_232	COG3584	3D domain protein
BD64_2320	COG1335	isochorismatase
BD64_2322	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BD64_2323	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BD64_2324	COG1760	l-serine dehydratase
BD64_2325	COG1760	l-serine dehydratase
BD64_2326	COG0814	amino acid
BD64_2329	COG1309	transcriptional regulator
BD64_233	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_2330	COG2814	Major facilitator Superfamily
BD64_2331	COG2184	nucleotidyltransferase activity
BD64_2334	COG0534	Mate efflux family protein
BD64_2341	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BD64_2345	COG0457	Tetratricopeptide repeat
BD64_2346	COG1609	Transcriptional regulator
BD64_2347	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BD64_2348	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BD64_2349	COG0561	phosphatase activity
BD64_235	COG1215	transferase activity, transferring glycosyl groups
BD64_2350	COG0673	inositol 2-dehydrogenase activity
BD64_2351	COG0738	Major facilitator superfamily
BD64_2355	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_2357	COG0583	DNA-binding transcription factor activity
BD64_2359	COG1139	Iron-sulfur cluster binding protein
BD64_2360	COG1556	Lactate utilization protein
BD64_2361	COG2271	Major facilitator Superfamily
BD64_2362	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_2363	COG2808	Putative FMN-binding domain
BD64_2364	COG0456	acetyltransferase
BD64_2365	COG1846	Transcriptional regulator
BD64_2366	COG2364	Membrane
BD64_2368	COG5002	protein histidine kinase activity
BD64_2368	COG3850	Histidine kinase
BD64_237	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_2371	COG0577	efflux transmembrane transporter activity
BD64_2372	COG1136	(ABC) transporter
BD64_2375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BD64_2376	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_2378	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_2379	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_238	COG1388	LysM domain
BD64_238	COG0791	NLP P60 protein
BD64_2382	COG1476	TRANSCRIPTIONal
BD64_2388	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BD64_2393	COG5002	protein histidine kinase activity
BD64_2393	COG3850	Histidine kinase
BD64_2394	COG0745	RESPONSE REGULATOR receiver
BD64_2399	COG2814	Major facilitator Superfamily
BD64_241	COG1368	sulfuric ester hydrolase activity
BD64_2411	COG0346	lactoylglutathione lyase activity
BD64_2414	COG1522	sequence-specific DNA binding
BD64_2417	COG0443	Heat shock 70 kDa protein
BD64_2421	COG0640	Transcriptional regulator
BD64_2422	COG0346	lactoylglutathione lyase activity
BD64_2423	COG0798	PFAM Bile acid sodium symporter
BD64_2429	COG1121	(ABC) transporter
BD64_2430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BD64_2431	COG0803	Belongs to the bacterial solute-binding protein 9 family
BD64_2432	COG2267	carboxylic ester hydrolase activity
BD64_2433	COG1575	Belongs to the MenA family. Type 1 subfamily
BD64_2435	COG5609	conserved protein (DUF2294)
BD64_2436	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD64_2438	COG0288	reversible hydration of carbon dioxide
BD64_2439	COG0415	Belongs to the DNA photolyase family
BD64_244	COG2389	metal-binding protein
BD64_2446	COG0598	Magnesium transport protein CorA
BD64_2447	COG0598	Magnesium transport protein CorA
BD64_2448	COG1846	Transcriptional regulator
BD64_2449	COG0583	DNA-binding transcription factor activity
BD64_2454	COG1335	isochorismatase
BD64_2455	COG2267	carboxylic ester hydrolase activity
BD64_2456	COG0753	catalase activity
BD64_2457	COG0737	Belongs to the 5'-nucleotidase family
BD64_246	COG1620	l-lactate permease
BD64_2463	COG1115	amino acid carrier protein
BD64_2465	COG2066	Belongs to the glutaminase family
BD64_2466	COG4191	Histidine kinase
BD64_2467	COG4191	Histidine kinase
BD64_2468	COG0784	Response regulator, receiver
BD64_2469	COG0697	spore germination
BD64_2470	COG0531	amino acid
BD64_2474	COG0281	malic enzyme
BD64_2476	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_2477	COG1114	Component of the transport system for branched-chain amino acids
BD64_2478	COG0531	amino acid
BD64_2479	COG0322	excinuclease ABC activity
BD64_248	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_2481	COG1396	sequence-specific DNA binding
BD64_2482	COG0252	asparaginase activity
BD64_2483	COG1027	Aspartate ammonia-lyase
BD64_2486	COG1063	alcohol dehydrogenase
BD64_249	COG1294	oxidase, subunit
BD64_2492	COG1113	amino acid transport
BD64_2493	COG1113	amino acid transport
BD64_2494	COG1280	lysine exporter protein (LysE YggA)
BD64_2495	COG3403	YqcI/YcgG family
BD64_2497	COG5577	PFAM Coat F domain
BD64_250	COG1271	oxidase subunit
BD64_2500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_2501	COG0574	Belongs to the PEP-utilizing enzyme family
BD64_2501	COG3848	Pyruvate phosphate dikinase
BD64_2504	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BD64_2511	COG1960	acyl-CoA dehydrogenase activity
BD64_2513	COG0640	Transcriptional regulator
BD64_2514	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_2517	COG1414	Transcriptional regulator
BD64_2518	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BD64_2519	COG1984	allophanate hydrolase subunit 2
BD64_2525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BD64_253	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BD64_2535	COG4335	DNA alkylation repair
BD64_2537	COG0833	amino acid
BD64_2539	COG0730	response to heat
BD64_254	COG0583	DNA-binding transcription factor activity
BD64_2545	COG0596	Alpha beta hydrolase
BD64_2546	COG0745	RESPONSE REGULATOR receiver
BD64_2547	COG0642	Histidine kinase
BD64_255	COG1511	domain protein
BD64_2551	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_2555	COG0456	acetyltransferase
BD64_2556	COG2207	Transcriptional regulator
BD64_256	COG0346	lactoylglutathione lyase activity
BD64_2561	COG1136	(ABC) transporter
BD64_2561	COG0577	efflux transmembrane transporter activity
BD64_2563	COG1725	Transcriptional regulator
BD64_2570	COG1846	Transcriptional regulator
BD64_2571	COG0778	Nitroreductase
BD64_2573	COG0714	Associated with various cellular activities
BD64_2579	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BD64_258	COG1301	dicarboxylic acid transport
BD64_2581	COG0753	catalase activity
BD64_2582	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BD64_2584	COG0463	Glycosyl transferase, family 2
BD64_2589	COG0463	Glycosyl transferase, family 2
BD64_259	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_2594	COG0714	Associated with various cellular activities
BD64_2598	COG0346	lactoylglutathione lyase activity
BD64_2599	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_26	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_2601	COG3279	Response regulator of the LytR AlgR family
BD64_2603	COG4377	Putative membrane peptidase family (DUF2324)
BD64_2606	COG3655	Transcriptional regulator
BD64_2608	COG1785	Belongs to the alkaline phosphatase family
BD64_2609	COG3239	Fatty acid desaturase
BD64_261	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_2610	COG1690	Belongs to the RtcB family
BD64_2611	COG0833	amino acid
BD64_2612	COG1414	Transcriptional regulator
BD64_2613	COG4187	Peptidase family M20/M25/M40
BD64_2614	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_2615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BD64_2617	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_262	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BD64_2621	COG2329	Antibiotic biosynthesis monooxygenase
BD64_2628	COG1070	Carbohydrate kinase
BD64_2629	COG2390	Transcriptional regulator
BD64_263	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BD64_2631	COG1172	Belongs to the binding-protein-dependent transport system permease family
BD64_2633	COG1879	ABC-type sugar transport system periplasmic component
BD64_2639	COG1595	DNA-templated transcription, initiation
BD64_2641	COG3584	3D domain protein
BD64_2641	COG1388	LysM domain
BD64_2649	COG1605	Chorismate mutase
BD64_2649	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BD64_265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_2650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BD64_2651	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BD64_2652	COG0287	Prephenate dehydrogenase
BD64_2655	COG1309	transcriptional regulator
BD64_2656	COG2409	Drug exporters of the RND superfamily
BD64_2656	COG1033	growth of symbiont in host cell
BD64_2657	COG2409	Drug exporters of the RND superfamily
BD64_2657	COG1033	growth of symbiont in host cell
BD64_2659	COG0488	(ABC) transporter
BD64_266	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_2660	COG1368	sulfuric ester hydrolase activity
BD64_2661	COG0861	Integral membrane protein TerC family
BD64_2663	COG0726	polysaccharide deacetylase
BD64_2665	COG4912	Dna alkylation repair
BD64_2669	COG2318	DinB family
BD64_267	COG1486	melibiose metabolic process
BD64_2670	COG0697	spore germination
BD64_2675	COG2746	aminoglycoside 3-N-acetyltransferase activity
BD64_268	COG3394	polysaccharide catabolic process
BD64_2683	COG1116	anion transmembrane transporter activity
BD64_2684	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_2685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_2686	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_2688	COG0628	permease
BD64_2697	COG1131	(ABC) transporter
BD64_27	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BD64_2701	COG5146	pantothenate kinase activity
BD64_2702	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BD64_2703	COG0436	Aminotransferase
BD64_2709	COG2226	methyltransferase
BD64_271	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BD64_271	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BD64_2712	COG2261	transglycosylase associated protein
BD64_2716	COG0477	Major facilitator Superfamily
BD64_2716	COG2814	Major facilitator Superfamily
BD64_2717	COG4533	DNA binding
BD64_2718	COG0789	Transcriptional regulator
BD64_2719	COG1664	Polymer-forming cytoskeletal
BD64_2721	COG2814	Major facilitator Superfamily
BD64_2725	COG1307	EDD domain protein, DegV family
BD64_2728	COG1164	Oligoendopeptidase f
BD64_273	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BD64_2735	COG0745	RESPONSE REGULATOR receiver
BD64_2736	COG5002	protein histidine kinase activity
BD64_2737	COG2936	dipeptidyl-peptidase activity
BD64_274	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BD64_2744	COG4948	Mandelate Racemase Muconate Lactonizing
BD64_2746	COG4166	transmembrane transport
BD64_2747	COG0519	Catalyzes the synthesis of GMP from XMP
BD64_2748	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BD64_275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BD64_2751	COG0586	Pfam SNARE associated Golgi protein
BD64_2758	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_2759	COG3938	Belongs to the proline racemase family
BD64_276	COG1316	TRANSCRIPTIONal
BD64_2761	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BD64_2762	COG1012	belongs to the aldehyde dehydrogenase family
BD64_2763	COG1115	amino acid carrier protein
BD64_2764	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BD64_2766	COG3397	chitin binding
BD64_277	COG1739	Uncharacterized protein family UPF0029
BD64_2771	COG4637	Psort location Cytoplasmic, score
BD64_2775	COG0514	ATP-dependent DNA helicase (RecQ)
BD64_2776	COG2105	PFAM AIG2 family protein
BD64_2779	COG3973	AAA domain
BD64_278	COG1307	EDD domain protein, DegV family
BD64_279	COG1733	regulation of RNA biosynthetic process
BD64_2790	COG2333	competence protein COMEC
BD64_2790	COG0658	competence protein
BD64_2795	COG2205	protein histidine kinase activity
BD64_2799	COG3397	chitin binding
BD64_28	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_280	COG0791	NLP P60 protein
BD64_280	COG1388	LysM domain
BD64_2800	COG2153	protein acetylation
BD64_2801	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BD64_2804	COG0740	serine-type endopeptidase activity
BD64_2806	COG4175	Glycine betaine
BD64_2806	COG0517	IMP dehydrogenase activity
BD64_2807	COG4176	ABC-type proline glycine betaine transport system permease component
BD64_281	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BD64_2813	COG0456	acetyltransferase
BD64_2813	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_2814	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_2816	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_2817	COG0022	dehydrogenase e1 component
BD64_2818	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_2819	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BD64_282	COG1040	competence protein
BD64_2823	COG1959	2 iron, 2 sulfur cluster binding
BD64_2827	COG1349	DNA-binding transcription factor activity
BD64_283	COG1278	Cold shock
BD64_2831	COG3284	Transcriptional regulator
BD64_2837	COG1309	transcriptional regulator
BD64_2838	COG3844	kynureninase activity
BD64_2839	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BD64_284	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BD64_2840	COG3483	tryptophan 2,3-dioxygenase activity
BD64_2843	COG3773	Cell wall hydrolase
BD64_2843	COG3409	Peptidoglycan-binding domain 1 protein
BD64_2844	COG2959	enzyme of heme biosynthesis
BD64_2847	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_2848	COG4129	membrane
BD64_285	COG0653	protein targeting
BD64_2854	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_2855	COG0697	spore germination
BD64_2857	COG0201	protein transport
BD64_286	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BD64_2861	COG3227	Zinc metalloprotease (Elastase)
BD64_2862	COG1523	belongs to the glycosyl hydrolase 13 family
BD64_2865	COG0076	glutamate decarboxylase activity
BD64_2870	COG1011	Hydrolase
BD64_2875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_288	COG2884	Cell division ATP-binding protein ftsE
BD64_2883	COG0322	excinuclease ABC activity
BD64_2886	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BD64_289	COG2177	Part of the ABC transporter FtsEX involved in
BD64_2891	COG4667	esterase of the alpha-beta hydrolase superfamily
BD64_2897	COG3878	Protein conserved in bacteria
BD64_29	COG2814	Major facilitator Superfamily
BD64_290	COG0793	Belongs to the peptidase S41A family
BD64_290	COG3409	Peptidoglycan-binding domain 1 protein
BD64_2904	COG1051	belongs to the nudix hydrolase family
BD64_2905	COG0592	DNA-directed DNA polymerase activity
BD64_2906	COG2816	NAD+ diphosphatase activity
BD64_2908	COG2223	nitrite transmembrane transporter activity
BD64_291	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_2915	COG0697	spore germination
BD64_2916	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_2917	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_292	COG1132	(ABC) transporter
BD64_2920	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_2924	COG2814	Major facilitator Superfamily
BD64_2929	COG0693	protein deglycase activity
BD64_2935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_2938	COG0604	alcohol dehydrogenase
BD64_2941	COG2205	protein histidine kinase activity
BD64_2944	COG1122	ATPase activity
BD64_2946	COG1794	racemase activity, acting on amino acids and derivatives
BD64_2947	COG1819	glycosyl
BD64_2949	COG5002	protein histidine kinase activity
BD64_295	COG0655	NAD(P)H dehydrogenase (quinone) activity
BD64_2951	COG0561	phosphatase activity
BD64_2958	COG2124	cytochrome p450
BD64_297	COG0583	DNA-binding transcription factor activity
BD64_2974	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BD64_2976	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_2977	COG0460	homoserine dehydrogenase
BD64_298	COG2855	membrane
BD64_2981	COG0577	efflux transmembrane transporter activity
BD64_2982	COG0577	efflux transmembrane transporter activity
BD64_2983	COG1136	(ABC) transporter
BD64_2988	COG2205	protein histidine kinase activity
BD64_2990	COG0745	RESPONSE REGULATOR receiver
BD64_2991	COG0745	RESPONSE REGULATOR receiver
BD64_2993	COG3773	Cell wall hydrolase
BD64_2996	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_2997	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_30	COG3275	phosphorelay sensor kinase activity
BD64_3000	COG1063	alcohol dehydrogenase
BD64_3002	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_3006	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_3010	COG2814	Major facilitator Superfamily
BD64_3012	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_3015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_3015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_302	COG0789	Transcriptional regulator
BD64_3020	COG3227	Zinc metalloprotease (Elastase)
BD64_3024	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BD64_3029	COG1686	Belongs to the peptidase S11 family
BD64_3030	COG2318	DinB family
BD64_3032	COG0572	uridine kinase
BD64_3033	COG1247	-acetyltransferase
BD64_3035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_3036	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BD64_3037	COG1024	Enoyl-CoA hydratase
BD64_3038	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BD64_3039	COG0511	ligase activity, forming carbon-carbon bonds
BD64_3040	COG0439	Biotin carboxylase
BD64_3041	COG1960	acyl-CoA dehydrogenase activity
BD64_3046	COG1131	(ABC) transporter
BD64_3049	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_3050	COG1252	NADH dehydrogenase
BD64_3052	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_3056	COG1309	transcriptional regulator
BD64_306	COG0556	nucleotide-excision repair
BD64_3061	COG1876	peptidase activity
BD64_3064	COG1476	TRANSCRIPTIONal
BD64_3065	COG0457	Tetratricopeptide repeat
BD64_3067	COG0737	Belongs to the 5'-nucleotidase family
BD64_3068	COG0737	Belongs to the 5'-nucleotidase family
BD64_307	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_3072	COG3718	enzyme involved in inositol metabolism
BD64_3076	COG1012	belongs to the aldehyde dehydrogenase family
BD64_3078	COG0673	inositol 2-dehydrogenase activity
BD64_3079	COG2814	Major facilitator Superfamily
BD64_3080	COG1609	Transcriptional regulator
BD64_3081	COG0671	phosphoesterase, PA-phosphatase related
BD64_3082	COG2367	Beta-lactamase
BD64_3085	COG0768	penicillin binding
BD64_3087	COG1595	DNA-templated transcription, initiation
BD64_309	COG1950	PFAM Membrane protein of
BD64_3091	COG2195	Cleaves the N-terminal amino acid of tripeptides
BD64_3099	COG1846	Transcriptional regulator
BD64_31	COG3279	Response regulator of the LytR AlgR family
BD64_3100	COG3961	Belongs to the TPP enzyme family
BD64_3101	COG2226	methyltransferase
BD64_3103	COG0500	methyltransferase
BD64_3103	COG3615	Tellurite resistance protein tehB
BD64_3104	COG0577	efflux transmembrane transporter activity
BD64_3104	COG1136	(ABC) transporter
BD64_3107	COG1309	transcriptional regulator
BD64_3112	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_3115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BD64_3116	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_3117	COG2971	BadF BadG BcrA BcrD
BD64_3122	COG1649	PFAM Uncharacterised BCR, COG1649
BD64_3127	COG1595	DNA-templated transcription, initiation
BD64_313	COG0110	maltose O-acetyltransferase activity
BD64_3132	COG1396	sequence-specific DNA binding
BD64_3136	COG1132	(ABC) transporter
BD64_3137	COG1132	(ABC) transporter
BD64_314	COG0457	Tetratricopeptide repeat
BD64_3140	COG2258	MOSC domain
BD64_3141	COG0583	DNA-binding transcription factor activity
BD64_3144	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BD64_3145	COG0583	DNA-binding transcription factor activity
BD64_315	COG0492	ferredoxin-NADP+ reductase activity
BD64_3153	COG0561	phosphatase activity
BD64_3154	COG0010	Belongs to the arginase family
BD64_3157	COG1278	Cold shock
BD64_3159	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_3167	COG1247	-acetyltransferase
BD64_317	COG1051	belongs to the nudix hydrolase family
BD64_3174	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_3183	COG2226	methyltransferase
BD64_3188	COG2814	Major facilitator Superfamily
BD64_3189	COG0596	Alpha beta hydrolase
BD64_319	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BD64_3193	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_3194	COG1187	pseudouridine synthase activity
BD64_3195	COG2329	Antibiotic biosynthesis monooxygenase
BD64_3198	COG1115	amino acid carrier protein
BD64_3200	COG2318	DinB family
BD64_3202	COG0776	regulation of translation
BD64_3205	COG2814	Major facilitator Superfamily
BD64_3206	COG3251	PFAM MbtH domain protein
BD64_3207	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BD64_3208	COG1535	isochorismatase
BD64_3208	COG3433	isochorismatase activity
BD64_3209	COG1021	2,3-dihydroxybenzoate-AMP ligase
BD64_321	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_3210	COG1169	isochorismate synthase
BD64_3211	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_3212	COG2223	nitrite transmembrane transporter activity
BD64_3216	COG0419	ATPase involved in DNA repair
BD64_3217	COG0420	3'-5' exonuclease activity
BD64_322	COG0740	serine-type endopeptidase activity
BD64_3220	COG1024	Enoyl-CoA hydratase
BD64_3221	COG1280	lysine exporter protein (LysE YggA)
BD64_3222	COG1012	belongs to the aldehyde dehydrogenase family
BD64_3223	COG2084	Dehydrogenase
BD64_3224	COG1960	acyl-CoA dehydrogenase activity
BD64_3225	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BD64_3226	COG2079	MmgE PrpD family protein
BD64_3227	COG0372	Belongs to the citrate synthase family
BD64_3228	COG4841	protein insertion into membrane
BD64_323	COG2323	membrane
BD64_3231	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_3231	COG4499	WXG100 protein secretion system (Wss), protein YukC
BD64_3239	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_3255	COG1715	Restriction endonuclease
BD64_3255	COG1787	Restriction endonuclease
BD64_326	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_3260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_3261	COG0671	phosphoesterase, PA-phosphatase related
BD64_3262	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BD64_3263	COG4326	sporulation control protein
BD64_3271	COG1509	lysine 2,3-aminomutase activity
BD64_3272	COG3829	transcription factor binding
BD64_3273	COG0456	acetyltransferase
BD64_3274	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_3275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BD64_3276	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BD64_3277	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_3280	COG5506	Protein of unknown function (DUF1694)
BD64_3281	COG1012	belongs to the aldehyde dehydrogenase family
BD64_3282	COG1253	flavin adenine dinucleotide binding
BD64_3289	COG1174	glycine betaine transport
BD64_3290	COG0517	IMP dehydrogenase activity
BD64_3290	COG1125	glycine betaine transport
BD64_3297	COG1070	Carbohydrate kinase
BD64_3304	COG1064	alcohol dehydrogenase
BD64_3305	COG1737	Transcriptional regulator
BD64_3307	COG2197	response regulator
BD64_3308	COG2203	Gaf domain
BD64_3308	COG4585	Histidine kinase
BD64_3309	COG0668	transmembrane transport
BD64_331	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BD64_3311	COG1051	belongs to the nudix hydrolase family
BD64_3312	COG1335	isochorismatase
BD64_3316	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_3317	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_3321	COG0367	asparagine synthase
BD64_3322	COG0071	Belongs to the small heat shock protein (HSP20) family
BD64_3323	COG1999	signal sequence binding
BD64_3324	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BD64_3325	COG1307	EDD domain protein, DegV family
BD64_3327	COG0805	protein transport
BD64_3329	COG1272	protein, Hemolysin III
BD64_3330	COG0204	Acyl-transferase
BD64_3331	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_3332	COG0768	penicillin binding
BD64_3335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_3339	COG0546	phosphoglycolate phosphatase activity
BD64_334	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BD64_3341	COG4473	ABC transporter
BD64_3342	COG1131	(ABC) transporter
BD64_3344	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BD64_3346	COG0456	acetyltransferase
BD64_3348	COG1794	racemase activity, acting on amino acids and derivatives
BD64_3349	COG1454	alcohol dehydrogenase
BD64_3350	COG2610	gluconate transmembrane transporter activity
BD64_3355	COG0733	neurotransmitter:sodium symporter activity
BD64_3358	COG5002	protein histidine kinase activity
BD64_3358	COG3850	Histidine kinase
BD64_3359	COG0745	RESPONSE REGULATOR receiver
BD64_336	COG0149	triose-phosphate isomerase activity
BD64_3360	COG0471	metal ion transport
BD64_3361	COG1929	Belongs to the glycerate kinase type-1 family
BD64_337	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BD64_3380	COG1674	ftsk spoiiie
BD64_3384	COG0017	Asparaginyl-tRNA synthetase
BD64_3385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BD64_3388	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BD64_339	COG4974	Belongs to the 'phage' integrase family
BD64_3394	COG0018	arginyl-trna synthetase
BD64_3395	COG2136	Putative SAM-dependent methyltransferase
BD64_3395	COG2521	methyltransferase
BD64_3398	COG1413	lyase activity
BD64_3399	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BD64_34	COG0628	permease
BD64_3402	COG0629	single-stranded DNA binding
BD64_3405	COG0488	(ABC) transporter
BD64_3406	COG1418	mRNA catabolic process
BD64_3409	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_3412	COG2359	stage V sporulation protein S
BD64_3419	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BD64_3420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD64_3421	COG2146	nitrite reductase [NAD(P)H] activity
BD64_3422	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BD64_3422	COG1587	Uroporphyrinogen-III synthase
BD64_3424	COG1648	precorrin-2 dehydrogenase activity
BD64_3427	COG2223	nitrite transmembrane transporter activity
BD64_3429	COG0314	molybdopterin synthase activity
BD64_3430	COG0303	'Molybdopterin
BD64_3431	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_3432	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD64_3433	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BD64_3437	COG2181	nitrate reductase activity
BD64_3438	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BD64_3439	COG1140	nitrate reductase beta subunit
BD64_344	COG4695	Portal protein
BD64_3440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BD64_3443	COG0714	Associated with various cellular activities
BD64_3444	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BD64_3445	COG1305	Transglutaminase-like
BD64_3446	COG0386	Belongs to the glutathione peroxidase family
BD64_3451	COG1595	DNA-templated transcription, initiation
BD64_3452	COG0604	alcohol dehydrogenase
BD64_3454	COG0346	lactoylglutathione lyase activity
BD64_3455	COG1082	Xylose isomerase domain protein TIM barrel
BD64_3459	COG2226	methyltransferase
BD64_3464	COG3874	Sporulation protein YtfJ
BD64_3473	COG0456	acetyltransferase
BD64_3479	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_3480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_3481	COG1819	glycosyl
BD64_3485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BD64_3487	COG0561	phosphatase activity
BD64_3491	COG2211	Major facilitator Superfamily
BD64_3492	COG0154	amidase activity
BD64_3494	COG1876	peptidase activity
BD64_3496	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_35	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_35	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_3500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_3501	COG1114	Component of the transport system for branched-chain amino acids
BD64_3504	COG1253	flavin adenine dinucleotide binding
BD64_3505	COG2839	Protein conserved in bacteria
BD64_3506	COG0702	epimerase
BD64_3509	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_3510	COG1607	acyl-coa hydrolase
BD64_3511	COG3689	TIGRFAM TIGR03943 family protein
BD64_3512	COG0701	Predicted permease
BD64_3514	COG2244	polysaccharide biosynthetic process
BD64_3515	COG0586	Pfam SNARE associated Golgi protein
BD64_3516	COG1051	belongs to the nudix hydrolase family
BD64_3517	COG5337	Spore coat protein CotH
BD64_3519	COG0406	alpha-ribazole phosphatase activity
BD64_3522	COG4166	transmembrane transport
BD64_3524	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BD64_3526	COG0702	epimerase
BD64_3528	COG3443	Belongs to the bacterial solute-binding protein 9 family
BD64_3528	COG0803	Belongs to the bacterial solute-binding protein 9 family
BD64_3539	COG0456	acetyltransferase
BD64_3540	COG0523	cobalamin synthesis protein
BD64_3541	COG4989	oxidoreductase activity
BD64_3543	COG1231	oxidoreductase activity
BD64_3545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_3548	COG0783	Belongs to the Dps family
BD64_3549	COG3949	Membrane
BD64_3552	COG0840	transmembrane signaling receptor activity
BD64_3557	COG2814	Major facilitator Superfamily
BD64_3558	COG0667	Aldo Keto reductase
BD64_3559	COG0640	Transcriptional regulator
BD64_3560	COG1404	Belongs to the peptidase S8 family
BD64_3561	COG2002	toxin-antitoxin pair type II binding
BD64_3562	COG0577	efflux transmembrane transporter activity
BD64_3563	COG0577	efflux transmembrane transporter activity
BD64_3570	COG1752	Esterase of the alpha-beta hydrolase superfamily
BD64_3572	COG1279	arginine transmembrane transporter activity
BD64_3573	COG2814	Major facilitator Superfamily
BD64_3574	COG2814	Major facilitator Superfamily
BD64_3576	COG1082	Xylose isomerase domain protein TIM barrel
BD64_3579	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_3580	COG4264	IucA IucC family
BD64_3582	COG1247	-acetyltransferase
BD64_3583	COG1285	pathogenesis
BD64_3585	COG0726	polysaccharide deacetylase
BD64_3586	COG5002	protein histidine kinase activity
BD64_3587	COG0745	RESPONSE REGULATOR receiver
BD64_3589	COG1316	TRANSCRIPTIONal
BD64_3594	COG0460	homoserine dehydrogenase
BD64_3598	COG0726	polysaccharide deacetylase
BD64_36	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BD64_3600	COG0300	oxidoreductase activity
BD64_3602	COG5002	protein histidine kinase activity
BD64_3603	COG0745	RESPONSE REGULATOR receiver
BD64_3604	COG1132	(ABC) transporter
BD64_3605	COG1132	(ABC) transporter
BD64_3607	COG1388	LysM domain
BD64_3607	COG0791	NLP P60 protein
BD64_3609	COG1686	Belongs to the peptidase S11 family
BD64_3613	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BD64_3614	COG4988	ABC transporter
BD64_3615	COG1294	oxidase, subunit
BD64_3616	COG1271	oxidase subunit
BD64_3618	COG1846	Transcriptional regulator
BD64_3622	COG0583	DNA-binding transcription factor activity
BD64_3626	COG0411	ABC transporter
BD64_3628	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_3629	COG2030	dehydratase
BD64_3630	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_3633	COG0523	cobalamin synthesis protein
BD64_3634	COG1231	oxidoreductase activity
BD64_3635	COG0039	L-malate dehydrogenase activity
BD64_3636	COG0628	permease
BD64_3639	COG0778	Nitroreductase
BD64_364	COG1346	cytolysis
BD64_3640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BD64_3641	COG1959	2 iron, 2 sulfur cluster binding
BD64_3642	COG0583	DNA-binding transcription factor activity
BD64_3643	COG0697	spore germination
BD64_3645	COG4549	nuclear export factor GLE1
BD64_3646	COG1276	copper resistance
BD64_3646	COG2372	response to copper ion
BD64_3648	COG1114	Component of the transport system for branched-chain amino acids
BD64_3649	COG1114	Component of the transport system for branched-chain amino acids
BD64_365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BD64_3650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_3656	COG2132	Multicopper oxidase
BD64_3657	COG0006	proline dipeptidase activity
BD64_366	COG1647	Serine aminopeptidase, S33
BD64_3661	COG4224	UPF0291 protein
BD64_3663	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BD64_3664	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_3666	COG2390	Transcriptional regulator
BD64_367	COG0557	exoribonuclease II activity
BD64_3671	COG0531	amino acid
BD64_3672	COG0531	amino acid
BD64_3674	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BD64_3677	COG1914	H( )-stimulated, divalent metal cation uptake system
BD64_3682	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_3688	COG4166	transmembrane transport
BD64_3689	COG1073	alpha beta
BD64_3693	COG0427	acetyl-CoA hydrolase
BD64_3694	COG3279	Response regulator of the LytR AlgR family
BD64_3696	COG3384	dioxygenase
BD64_3697	COG2814	Major facilitator Superfamily
BD64_37	COG1309	transcriptional regulator
BD64_3702	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BD64_3704	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BD64_3705	COG0440	acetolactate synthase activity
BD64_3706	COG0028	Belongs to the TPP enzyme family
BD64_3707	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_3709	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_3713	COG2084	Dehydrogenase
BD64_3716	COG2323	membrane
BD64_3717	COG5566	PFAM Mor transcription activator
BD64_3719	COG0733	neurotransmitter:sodium symporter activity
BD64_3720	COG2244	polysaccharide biosynthetic process
BD64_3723	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_3724	COG2223	nitrite transmembrane transporter activity
BD64_3725	COG4166	transmembrane transport
BD64_3727	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BD64_3729	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_3730	COG0477	Major facilitator Superfamily
BD64_3731	COG0477	Major facilitator Superfamily
BD64_3733	COG1966	Carbon starvation protein
BD64_3738	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_3739	COG1051	belongs to the nudix hydrolase family
BD64_3750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_3751	COG0784	Response regulator, receiver
BD64_3752	COG4191	Histidine kinase
BD64_3753	COG0281	malic enzyme
BD64_3754	COG1027	Aspartate ammonia-lyase
BD64_3756	COG0528	UMP kinase activity
BD64_3757	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_376	COG3223	Belongs to the PsiE family
BD64_3760	COG1131	(ABC) transporter
BD64_3767	COG2733	membrane
BD64_377	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_3774	COG0785	Cytochrome C biogenesis protein
BD64_3778	COG3340	Belongs to the peptidase S51 family
BD64_3779	COG0534	Mate efflux family protein
BD64_3780	COG0534	Mate efflux family protein
BD64_3784	COG0114	fumarate hydratase activity
BD64_3785	COG1757	Na H antiporter
BD64_3786	COG1216	Glycosyl transferase, family 2
BD64_3786	COG0438	transferase activity, transferring glycosyl groups
BD64_3788	COG0701	Predicted permease
BD64_3789	COG0523	cobalamin synthesis protein
BD64_3790	COG0697	spore germination
BD64_3791	COG1802	Transcriptional regulator
BD64_3797	COG0367	asparagine synthase
BD64_38	COG0463	Glycosyl transferase, family 2
BD64_380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BD64_3804	COG0406	alpha-ribazole phosphatase activity
BD64_3806	COG1686	Belongs to the peptidase S11 family
BD64_381	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BD64_3811	COG1234	tRNA 3'-trailer cleavage
BD64_3812	COG1177	transmembrane transport
BD64_3813	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_3814	COG3842	ATPase activity
BD64_3820	COG2329	Antibiotic biosynthesis monooxygenase
BD64_3824	COG1309	transcriptional regulator
BD64_3829	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_383	COG3290	protein histidine kinase activity
BD64_383	COG0840	transmembrane signaling receptor activity
BD64_3830	COG4786	Flagellar basal body rod
BD64_3831	COG1419	protein localization to endoplasmic reticulum
BD64_3832	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BD64_3833	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BD64_3835	COG1987	bacterial-type flagellum assembly
BD64_3836	COG1338	Plays a role in the flagellum-specific transport system
BD64_3838	COG1776	CheC inhibitor of MCP methylation
BD64_3838	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_3840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_3841	COG0741	lytic transglycosylase activity
BD64_3842	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BD64_3847	COG0463	Glycosyl transferase, family 2
BD64_3847	COG0457	Tetratricopeptide repeat
BD64_385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BD64_3853	COG0463	Glycosyl transferase, family 2
BD64_3855	COG0835	chemotaxis
BD64_3855	COG0784	Response regulator, receiver
BD64_386	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BD64_3864	COG1157	protein secretion by the type III secretion system
BD64_3866	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_3868	COG1766	The M ring may be actively involved in energy transduction
BD64_3869	COG1677	Flagellar hook-basal body complex protein FliE
BD64_387	COG1252	NADH dehydrogenase
BD64_3870	COG1558	bacterial-type flagellum-dependent cell motility
BD64_3871	COG1815	bacterial-type flagellum-dependent cell motility
BD64_3876	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BD64_3877	COG1256	bacterial-type flagellum assembly
BD64_3881	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BD64_3884	COG1776	CheC inhibitor of MCP methylation
BD64_3884	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_3885	COG2198	Histidine kinase
BD64_3885	COG0643	Histidine kinase
BD64_3886	COG2198	Histidine kinase
BD64_3886	COG0643	Histidine kinase
BD64_3887	COG2201	protein-glutamate methylesterase activity
BD64_3888	COG1360	Flagellar Motor Protein
BD64_3889	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BD64_389	COG1733	regulation of RNA biosynthetic process
BD64_3891	COG1923	regulation of RNA biosynthetic process
BD64_390	COG2814	Major facilitator Superfamily
BD64_3902	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BD64_3903	COG2323	membrane
BD64_3905	COG4978	Transcriptional regulator
BD64_3905	COG0789	Transcriptional regulator
BD64_3906	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_3907	COG0475	glutathione-regulated potassium exporter activity
BD64_3909	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_391	COG0656	L-ascorbic acid biosynthetic process
BD64_3910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_3911	COG3162	membrane
BD64_3914	COG1280	lysine exporter protein (LysE YggA)
BD64_3922	COG0328	RNA-DNA hybrid ribonuclease activity
BD64_3926	COG0454	-acetyltransferase
BD64_3929	COG0438	transferase activity, transferring glycosyl groups
BD64_3930	COG1215	transferase activity, transferring glycosyl groups
BD64_3933	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BD64_3940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_3943	COG0754	glutathionylspermidine amidase activity
BD64_3948	COG0456	acetyltransferase
BD64_3950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_3952	COG2311	Membrane
BD64_3953	COG2233	PERMEase
BD64_3955	COG0024	Methionine aminopeptidase
BD64_3956	COG3173	Aminoglycoside phosphotransferase
BD64_3958	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BD64_3959	COG1199	ATP-dependent helicase activity
BD64_396	COG2910	NAD(P)H-binding
BD64_3961	COG0116	Belongs to the methyltransferase superfamily
BD64_3963	COG4474	Belongs to the UPF0398 family
BD64_397	COG1115	amino acid carrier protein
BD64_3972	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_3972	COG4499	WXG100 protein secretion system (Wss), protein YukC
BD64_3974	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BD64_3975	COG3935	DnaD domain protein
BD64_3979	COG1199	ATP-dependent helicase activity
BD64_3979	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BD64_398	COG1115	amino acid carrier protein
BD64_3986	COG0438	transferase activity, transferring glycosyl groups
BD64_3987	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_399	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_3990	COG1694	Mazg nucleotide pyrophosphohydrolase
BD64_3991	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_3993	COG2738	Putative neutral zinc metallopeptidase
BD64_3996	COG4347	Protein of unknown function (DUF1405)
BD64_3998	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BD64_400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_4002	COG0457	Tetratricopeptide repeat
BD64_4003	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BD64_4006	COG0105	UTP biosynthetic process
BD64_4007	COG0142	geranyltranstransferase activity
BD64_4009	COG0142	geranyltranstransferase activity
BD64_4012	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_402	COG2311	Membrane
BD64_4026	COG0252	asparaginase activity
BD64_4027	COG0492	ferredoxin-NADP+ reductase activity
BD64_4031	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BD64_4032	COG4862	establishment of competence for transformation
BD64_4034	COG1408	metallophosphoesterase
BD64_4036	COG1266	CAAX protease self-immunity
BD64_4037	COG0514	ATP-dependent DNA helicase (RecQ)
BD64_4038	COG4955	Helix-turn-helix domain
BD64_4039	COG1141	Ferredoxin
BD64_4040	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BD64_4043	COG2096	Adenosyltransferase
BD64_4044	COG5002	protein histidine kinase activity
BD64_4045	COG0745	RESPONSE REGULATOR receiver
BD64_4046	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BD64_4047	COG1333	cytochrome c biogenesis protein
BD64_4049	COG1187	pseudouridine synthase activity
BD64_405	COG1611	Belongs to the LOG family
BD64_4050	COG0700	Nucleoside recognition
BD64_4051	COG2715	membrane protein required for spore maturation
BD64_4052	COG1686	Belongs to the peptidase S11 family
BD64_4053	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_4056	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BD64_4056	COG0392	lysyltransferase activity
BD64_4060	COG5002	protein histidine kinase activity
BD64_4061	COG0582	viral genome integration into host DNA
BD64_4063	COG1801	Protein of unknown function DUF72
BD64_4064	COG3852	Histidine kinase
BD64_4067	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_4068	COG1392	Phosphate transport regulator
BD64_4069	COG0306	phosphate transporter
BD64_4070	COG0730	response to heat
BD64_4073	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BD64_4073	COG1017	nitric oxide dioxygenase activity
BD64_4078	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BD64_408	COG0783	Belongs to the Dps family
BD64_4080	COG1114	Component of the transport system for branched-chain amino acids
BD64_4082	COG2197	response regulator
BD64_4083	COG4585	Histidine kinase
BD64_4084	COG4758	membrane
BD64_4087	COG1757	Na H antiporter
BD64_409	COG1115	amino acid carrier protein
BD64_4091	COG0733	neurotransmitter:sodium symporter activity
BD64_4092	COG1648	precorrin-2 dehydrogenase activity
BD64_4096	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD64_4097	COG0529	Catalyzes the synthesis of activated sulfate
BD64_410	COG0490	domain, Protein
BD64_4101	COG0019	diaminopimelate decarboxylase activity
BD64_4103	COG1368	sulfuric ester hydrolase activity
BD64_4104	COG1183	phosphatidylcholine synthase activity
BD64_4107	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BD64_411	COG0475	glutathione-regulated potassium exporter activity
BD64_4114	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BD64_4119	COG0473	3-isopropylmalate dehydrogenase activity
BD64_4121	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BD64_4122	COG0440	acetolactate synthase activity
BD64_4123	COG0028	Belongs to the TPP enzyme family
BD64_4124	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_4129	COG3874	Sporulation protein YtfJ
BD64_4130	COG4709	membrane
BD64_4131	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_4132	COG1301	dicarboxylic acid transport
BD64_4134	COG1846	Transcriptional regulator
BD64_4137	COG1968	undecaprenyl-diphosphatase activity
BD64_4138	COG0534	Mate efflux family protein
BD64_414	COG1741	Belongs to the pirin family
BD64_4142	COG3173	Aminoglycoside phosphotransferase
BD64_4145	COG0716	FMN binding
BD64_415	COG3227	Zinc metalloprotease (Elastase)
BD64_4150	COG1696	Membrane protein involved in D-alanine export
BD64_4152	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BD64_4153	COG2070	2-Nitropropane dioxygenase
BD64_4154	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_4156	COG1335	isochorismatase
BD64_4158	COG1522	sequence-specific DNA binding
BD64_416	COG2151	metal-sulfur cluster biosynthetic enzyme
BD64_4161	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_4162	COG1131	(ABC) transporter
BD64_4164	COG1131	(ABC) transporter
BD64_4165	COG1725	Transcriptional regulator
BD64_4166	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD64_4167	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD64_4169	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD64_4170	COG1780	Probably involved in ribonucleotide reductase function
BD64_4176	COG4873	Protein conserved in bacteria
BD64_4179	COG0720	synthase
BD64_4181	COG5002	protein histidine kinase activity
BD64_4183	COG2318	DinB family
BD64_4185	COG1846	Transcriptional regulator
BD64_4186	COG3852	Histidine kinase
BD64_4188	COG2861	carbohydrate metabolic process
BD64_419	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_4190	COG0235	Class ii aldolase
BD64_4195	COG1349	DNA-binding transcription factor activity
BD64_4198	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BD64_4201	COG3842	ATPase activity
BD64_4202	COG3842	ATPase activity
BD64_4204	COG1840	ABC-type Fe3 transport system, periplasmic component
BD64_4207	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_4209	COG3243	poly(R)-hydroxyalkanoic acid synthase
BD64_4210	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_4214	COG2030	dehydratase
BD64_4216	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_4217	COG0861	Integral membrane protein TerC family
BD64_4218	COG2116	formate transmembrane transporter activity
BD64_4220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BD64_4224	COG2186	Transcriptional regulator
BD64_4225	COG5002	protein histidine kinase activity
BD64_4226	COG0745	RESPONSE REGULATOR receiver
BD64_4228	COG3835	regulator
BD64_4229	COG0277	FAD linked oxidase domain protein
BD64_423	COG0745	RESPONSE REGULATOR receiver
BD64_4230	COG0247	lactate metabolic process
BD64_4231	COG2340	Cysteine-rich secretory protein family
BD64_4233	COG0564	pseudouridine synthase activity
BD64_4235	COG2409	Drug exporters of the RND superfamily
BD64_4237	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BD64_4238	COG1177	transmembrane transport
BD64_4239	COG1176	ABC-type spermidine putrescine transport system, permease component I
BD64_424	COG1376	ErfK ybiS ycfS ynhG family protein
BD64_4240	COG3842	ATPase activity
BD64_4241	COG1012	belongs to the aldehyde dehydrogenase family
BD64_4247	COG0681	Belongs to the peptidase S26 family
BD64_4248	COG1686	Belongs to the peptidase S11 family
BD64_4250	COG2226	methyltransferase
BD64_426	COG0586	Pfam SNARE associated Golgi protein
BD64_4261	COG1476	TRANSCRIPTIONal
BD64_4263	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_4273	COG5634	Uncharacterized conserved protein (DUF2278)
BD64_4274	COG1620	l-lactate permease
BD64_4281	COG0512	Glutamine amidotransferase of anthranilate synthase
BD64_4281	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BD64_4283	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_4284	COG5492	domain, Protein
BD64_4287	COG2382	esterase
BD64_4288	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BD64_4289	COG2153	protein acetylation
BD64_4297	COG1091	dTDP-4-dehydrorhamnose reductase activity
BD64_43	COG0488	(ABC) transporter
BD64_4300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BD64_4304	COG0463	Glycosyl transferase, family 2
BD64_4304	COG0457	Tetratricopeptide repeat
BD64_4308	COG1216	Glycosyl transferase, family 2
BD64_4309	COG0772	Belongs to the SEDS family
BD64_4310	COG0772	Belongs to the SEDS family
BD64_4314	COG0564	pseudouridine synthase activity
BD64_4315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BD64_4316	COG2357	RelA SpoT domain protein
BD64_4318	COG4116	CYTH
BD64_4319	COG2346	COG2346, Truncated hemoglobins
BD64_4322	COG1164	Oligoendopeptidase f
BD64_4324	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_4325	COG4862	establishment of competence for transformation
BD64_4326	COG0861	Integral membrane protein TerC family
BD64_4327	COG1393	Belongs to the ArsC family
BD64_4329	COG4166	transmembrane transport
BD64_433	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_4330	COG0534	Mate efflux family protein
BD64_4331	COG4608	Belongs to the ABC transporter superfamily
BD64_4332	COG0444	Belongs to the ABC transporter superfamily
BD64_4333	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_4334	COG0601	transmembrane transport
BD64_4335	COG4166	transmembrane transport
BD64_4337	COG0180	Tryptophanyl-tRNA synthetase
BD64_4339	COG5504	Zn-dependent protease
BD64_4340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BD64_4341	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_4344	COG2267	carboxylic ester hydrolase activity
BD64_4346	COG0542	response to heat
BD64_4348	COG0561	phosphatase activity
BD64_435	COG0706	membrane insertase activity
BD64_4351	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_4353	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_4355	COG2996	Protein conserved in bacteria
BD64_4359	COG0004	ammonium transporteR
BD64_4360	COG0753	catalase activity
BD64_4362	COG0367	asparagine synthase
BD64_4367	COG0179	Fumarylacetoacetate (FAA) hydrolase
BD64_437	COG0531	amino acid
BD64_4375	COG1074	ATP-dependent DNA helicase activity
BD64_4376	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BD64_4378	COG0398	Pfam SNARE associated Golgi protein
BD64_4379	COG4903	ComK protein
BD64_438	COG2814	Major facilitator Superfamily
BD64_4382	COG1278	Cold shock
BD64_4384	COG2224	Isocitrate lyase
BD64_4385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BD64_4386	COG0497	DNA recombination
BD64_4389	COG0697	spore germination
BD64_4390	COG0840	transmembrane signaling receptor activity
BD64_4391	COG0501	Belongs to the peptidase M48B family
BD64_4396	COG0745	RESPONSE REGULATOR receiver
BD64_4397	COG2205	protein histidine kinase activity
BD64_4400	COG2207	Transcriptional regulator
BD64_4400	COG3708	Transcriptional regulator
BD64_4401	COG1595	DNA-templated transcription, initiation
BD64_4403	COG1078	dGTPase activity
BD64_4404	COG1408	metallophosphoesterase
BD64_4411	COG3209	COG3209 Rhs family protein
BD64_4417	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_4419	COG0095	Lipoate-protein ligase
BD64_442	COG0840	transmembrane signaling receptor activity
BD64_4420	COG1234	tRNA 3'-trailer cleavage
BD64_4422	COG1609	Transcriptional regulator
BD64_4427	COG1511	domain protein
BD64_4428	COG1309	transcriptional regulator
BD64_443	COG0011	TIGRFAM Protein of
BD64_4437	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BD64_4438	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_4439	COG2329	Antibiotic biosynthesis monooxygenase
BD64_4440	COG3428	Bacterial PH domain
BD64_4441	COG3402	PFAM membrane-flanked domain
BD64_4450	COG3428	Bacterial PH domain
BD64_4452	COG3402	PFAM membrane-flanked domain
BD64_4454	COG1309	transcriptional regulator
BD64_4457	COG4473	ABC transporter
BD64_4458	COG1131	(ABC) transporter
BD64_4459	COG0537	adenosine 5'-monophosphoramidase activity
BD64_446	COG1686	Belongs to the peptidase S11 family
BD64_4460	COG4980	gas vesicle protein
BD64_4464	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_4465	COG3973	AAA domain
BD64_4467	COG0477	Major facilitator Superfamily
BD64_4468	COG0477	Major facilitator Superfamily
BD64_4476	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BD64_4478	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BD64_4479	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BD64_448	COG1024	Enoyl-CoA hydratase
BD64_448	COG1250	3-hydroxyacyl-CoA dehydrogenase
BD64_4483	COG2267	carboxylic ester hydrolase activity
BD64_4485	COG0457	Tetratricopeptide repeat
BD64_4488	COG0346	lactoylglutathione lyase activity
BD64_4489	COG2814	Major facilitator Superfamily
BD64_449	COG0183	Belongs to the thiolase family
BD64_4490	COG1309	transcriptional regulator
BD64_4494	COG4717	serine-type aminopeptidase activity
BD64_4495	COG0420	3'-5' exonuclease activity
BD64_450	COG1960	acyl-CoA dehydrogenase activity
BD64_4501	COG0393	Putative heavy-metal-binding
BD64_4506	COG2198	Histidine kinase
BD64_4506	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_4506	COG0784	Response regulator, receiver
BD64_4506	COG2205	protein histidine kinase activity
BD64_4507	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BD64_4508	COG2208	phosphoserine phosphatase activity
BD64_451	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_4510	COG1191	sigma factor activity
BD64_4515	COG3237	CsbD-like
BD64_452	COG1309	transcriptional regulator
BD64_4525	COG3437	response regulator, receiver
BD64_4525	COG2770	Histidine kinase
BD64_4530	COG1959	2 iron, 2 sulfur cluster binding
BD64_4531	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_4532	COG2376	Dihydroxyacetone kinase
BD64_4534	COG2376	Dihydroxyacetone kinase
BD64_4538	COG1183	phosphatidylcholine synthase activity
BD64_4543	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BD64_4543	COG3320	Male sterility
BD64_4553	COG0477	Major facilitator Superfamily
BD64_4561	COG0305	Participates in initiation and elongation during chromosome replication
BD64_4564	COG4978	Transcriptional regulator
BD64_4564	COG0789	Transcriptional regulator
BD64_4569	COG3181	Tripartite tricarboxylate transporter family receptor
BD64_457	COG0039	L-malate dehydrogenase activity
BD64_4570	COG4565	transcriptional regulatory protein
BD64_4571	COG3290	protein histidine kinase activity
BD64_4572	COG0477	Major facilitator Superfamily
BD64_4578	COG4608	Belongs to the ABC transporter superfamily
BD64_4579	COG0444	Belongs to the ABC transporter superfamily
BD64_4580	COG0444	Belongs to the ABC transporter superfamily
BD64_4581	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_4582	COG0601	transmembrane transport
BD64_4589	COG3938	Belongs to the proline racemase family
BD64_4593	COG1363	Peptidase, m42
BD64_4596	COG1024	Enoyl-CoA hydratase
BD64_4599	COG1696	Membrane protein involved in D-alanine export
BD64_46	COG1607	acyl-coa hydrolase
BD64_4602	COG4196	transglutaminase domain protein
BD64_4603	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_4605	COG2244	polysaccharide biosynthetic process
BD64_4606	COG0653	protein targeting
BD64_4610	COG0659	secondary active sulfate transmembrane transporter activity
BD64_4613	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BD64_4617	COG0561	phosphatase activity
BD64_4620	COG3527	Alpha-acetolactate decarboxylase
BD64_4621	COG0028	Belongs to the TPP enzyme family
BD64_4627	COG0189	ligase activity
BD64_4630	COG1126	abc transporter atp-binding protein
BD64_4631	COG0765	amino acid transport
BD64_4632	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_4633	COG1132	(ABC) transporter
BD64_4634	COG1132	(ABC) transporter
BD64_4635	COG1132	(ABC) transporter
BD64_4636	COG1012	belongs to the aldehyde dehydrogenase family
BD64_4638	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BD64_4639	COG0531	amino acid
BD64_4641	COG0693	protein deglycase activity
BD64_4641	COG0753	catalase activity
BD64_4642	COG0693	protein deglycase activity
BD64_4644	COG2211	Major facilitator Superfamily
BD64_4645	COG4533	DNA binding
BD64_4646	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_4648	COG1733	regulation of RNA biosynthetic process
BD64_4649	COG2814	Major facilitator Superfamily
BD64_4650	COG1309	transcriptional regulator
BD64_4651	COG2076	Multidrug Resistance protein
BD64_4652	COG2076	Multidrug Resistance protein
BD64_4654	COG1522	sequence-specific DNA binding
BD64_4655	COG0697	spore germination
BD64_4658	COG2259	Doxx family
BD64_466	COG1393	Belongs to the ArsC family
BD64_4660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_4660	COG1263	PTS System
BD64_4662	COG1737	Transcriptional regulator
BD64_4664	COG0475	glutathione-regulated potassium exporter activity
BD64_4665	COG0531	amino acid
BD64_4671	COG0586	Pfam SNARE associated Golgi protein
BD64_4678	COG3546	catalase activity
BD64_4679	COG1114	Component of the transport system for branched-chain amino acids
BD64_468	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BD64_4682	COG5522	Integral membrane protein (intg_mem_TP0381)
BD64_4684	COG1136	(ABC) transporter
BD64_4685	COG0577	efflux transmembrane transporter activity
BD64_4686	COG1388	LysM domain
BD64_4686	COG3584	3D domain protein
BD64_469	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_4690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_4691	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_4692	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_4692	COG3711	transcriptional antiterminator
BD64_4695	COG1283	sodium-dependent phosphate transmembrane transporter activity
BD64_4696	COG0604	alcohol dehydrogenase
BD64_4697	COG1316	TRANSCRIPTIONal
BD64_4699	COG0730	response to heat
BD64_4700	COG2210	Belongs to the sulfur carrier protein TusA family
BD64_4702	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_4704	COG0425	Belongs to the sulfur carrier protein TusA family
BD64_4705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_4705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_4706	COG0425	Belongs to the sulfur carrier protein TusA family
BD64_4706	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_4707	COG1937	Protein conserved in bacteria
BD64_4708	COG0446	pyridine nucleotide-disulphide oxidoreductase
BD64_471	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_4713	COG2719	SpoVR family
BD64_4714	COG0778	Nitroreductase
BD64_472	COG2011	ABC-type metal ion transport system permease component
BD64_4722	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BD64_4723	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_4725	COG1609	Transcriptional regulator
BD64_4726	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_4726	COG1263	PTS System
BD64_4727	COG1621	beta-fructofuranosidase activity
BD64_4728	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BD64_473	COG1464	Belongs to the NlpA lipoprotein family
BD64_4732	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_4733	COG2252	PERMEase
BD64_4736	COG1846	Transcriptional regulator
BD64_4737	COG2814	Major facilitator Superfamily
BD64_4738	COG2205	protein histidine kinase activity
BD64_474	COG1464	Belongs to the NlpA lipoprotein family
BD64_4745	COG0351	phosphomethylpyrimidine kinase
BD64_4746	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_4748	COG2104	thiamine diphosphate biosynthetic process
BD64_4749	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_475	COG0396	ATPase activity
BD64_4750	COG0352	thiamine-phosphate diphosphorylase activity
BD64_4751	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_4752	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_4753	COG1116	anion transmembrane transporter activity
BD64_4754	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BD64_4758	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BD64_476	COG0719	Fe-S assembly protein
BD64_477	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BD64_478	COG0822	iron-sulfur transferase activity
BD64_4783	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BD64_4785	COG0581	inorganic phosphate transmembrane transporter activity
BD64_4786	COG0573	inorganic phosphate transmembrane transporter activity
BD64_4787	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BD64_4788	COG1918	ferrous iron import across plasma membrane
BD64_4788	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_4789	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_479	COG0719	Fe-S assembly protein
BD64_4790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_4792	COG0531	amino acid
BD64_4793	COG0697	spore germination
BD64_4794	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_4797	COG4990	cell redox homeostasis
BD64_4798	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BD64_4799	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BD64_48	COG0840	transmembrane signaling receptor activity
BD64_4802	COG0569	domain protein
BD64_4802	COG0475	glutathione-regulated potassium exporter activity
BD64_4807	COG2252	PERMEase
BD64_4808	COG1113	amino acid transport
BD64_481	COG1695	Transcriptional regulator
BD64_4811	COG1114	Component of the transport system for branched-chain amino acids
BD64_4812	COG3104	oligopeptide transport
BD64_4815	COG1476	TRANSCRIPTIONal
BD64_4816	COG3584	3D domain protein
BD64_4816	COG1388	LysM domain
BD64_4817	COG0840	transmembrane signaling receptor activity
BD64_4818	COG1968	undecaprenyl-diphosphatase activity
BD64_482	COG0737	Belongs to the 5'-nucleotidase family
BD64_4823	COG3568	Endonuclease Exonuclease Phosphatase
BD64_4826	COG1063	alcohol dehydrogenase
BD64_483	COG3377	Domain of unknown function (DUF1805)
BD64_4830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BD64_4831	COG1879	ABC-type sugar transport system periplasmic component
BD64_4832	COG1172	Belongs to the binding-protein-dependent transport system permease family
BD64_4833	COG1129	ABC transporter
BD64_4835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BD64_4836	COG1609	Transcriptional regulator
BD64_4837	COG0477	Major facilitator Superfamily
BD64_4838	COG0477	Major facilitator Superfamily
BD64_4839	COG1846	Transcriptional regulator
BD64_4840	COG2271	Major facilitator Superfamily
BD64_4842	COG4608	Belongs to the ABC transporter superfamily
BD64_4843	COG0601	transmembrane transport
BD64_4845	COG0747	negative chemotaxis
BD64_4848	COG0659	secondary active sulfate transmembrane transporter activity
BD64_485	COG0739	heme binding
BD64_4851	COG5002	protein histidine kinase activity
BD64_4852	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BD64_4853	COG2378	regulation of single-species biofilm formation
BD64_4858	COG0833	amino acid
BD64_4859	COG0765	amino acid transport
BD64_4860	COG0765	amino acid transport
BD64_4861	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_4862	COG1126	abc transporter atp-binding protein
BD64_4863	COG1115	amino acid carrier protein
BD64_4864	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_4866	COG0697	spore germination
BD64_4869	COG0366	Alpha amylase catalytic
BD64_4870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_4870	COG1263	PTS System
BD64_4871	COG2188	Transcriptional regulator
BD64_4872	COG0531	amino acid
BD64_4876	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_4877	COG0714	Associated with various cellular activities
BD64_4878	COG4548	von Willebrand factor, type A
BD64_4880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_4881	COG0156	8-amino-7-oxononanoate synthase activity
BD64_4882	COG2226	methyltransferase
BD64_4884	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_4885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_4886	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_4887	COG3104	oligopeptide transport
BD64_4890	COG1620	l-lactate permease
BD64_4891	COG1027	Aspartate ammonia-lyase
BD64_4892	COG1253	flavin adenine dinucleotide binding
BD64_4893	COG0346	lactoylglutathione lyase activity
BD64_4894	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_4895	COG1316	TRANSCRIPTIONal
BD64_4896	COG2720	vancomycin resistance protein
BD64_490	COG4377	Putative membrane peptidase family (DUF2324)
BD64_4900	COG3227	Zinc metalloprotease (Elastase)
BD64_4903	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BD64_4904	COG2217	Heavy metal translocating P-type atpase
BD64_4905	COG0640	Transcriptional regulator
BD64_4906	COG0531	amino acid
BD64_491	COG0789	Transcriptional regulator
BD64_4911	COG3383	formate dehydrogenase (NAD+) activity
BD64_4912	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BD64_4913	COG0454	-acetyltransferase
BD64_4913	COG0456	acetyltransferase
BD64_4915	COG0745	RESPONSE REGULATOR receiver
BD64_4916	COG5002	protein histidine kinase activity
BD64_4918	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_4921	COG0281	malic enzyme
BD64_4922	COG3493	citrate carrier protein
BD64_4923	COG4565	transcriptional regulatory protein
BD64_4924	COG3290	protein histidine kinase activity
BD64_4926	COG4990	cell redox homeostasis
BD64_4928	COG5002	protein histidine kinase activity
BD64_4929	COG0745	RESPONSE REGULATOR receiver
BD64_493	COG4470	Protein conserved in bacteria
BD64_4930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BD64_4932	COG0395	ABC-type sugar transport system, permease component
BD64_4933	COG1175	transmembrane transport
BD64_4934	COG3842	ATPase activity
BD64_4935	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BD64_4939	COG2851	Citrate transporter
BD64_4940	COG4565	transcriptional regulatory protein
BD64_4941	COG3290	protein histidine kinase activity
BD64_4943	COG2268	Band 7 protein
BD64_4944	COG1585	Membrane protein implicated in regulation of membrane protease activity
BD64_4946	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_4950	COG2766	serine protein kinase
BD64_4953	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BD64_4955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BD64_4957	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BD64_4958	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BD64_496	COG1494	fructose-1,6-bisphosphatase
BD64_497	COG2445	Protein of unknown function DUF86
BD64_4983	COG0735	belongs to the Fur family
BD64_4984	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BD64_4988	COG4555	ABC transporter
BD64_499	COG0647	UMP catabolic process
BD64_4990	COG0069	glutamate synthase activity
BD64_4990	COG0067	glutamate synthase
BD64_4990	COG0070	glutamate synthase
BD64_4991	COG4129	membrane
BD64_4992	COG1132	(ABC) transporter
BD64_4997	COG1194	a g-specific adenine glycosylase
BD64_4998	COG1988	membrane-bound metal-dependent
BD64_500	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_5004	COG1090	epimerase
BD64_5005	COG1228	amidohydrolase
BD64_5009	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BD64_5012	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BD64_5012	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_5015	COG0463	Glycosyl transferase, family 2
BD64_5018	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_5019	COG1263	PTS System
BD64_5019	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_502	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BD64_5020	COG2066	Belongs to the glutaminase family
BD64_5025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_5026	COG0833	amino acid
BD64_5028	COG3829	transcription factor binding
BD64_503	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_5030	COG0101	tRNA pseudouridine synthase activity
BD64_505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BD64_506	COG4837	Protein of unknown function (DUF1462)
BD64_5077	COG1484	DNA-dependent DNA replication
BD64_5084	COG1396	sequence-specific DNA binding
BD64_5088	COG0582	viral genome integration into host DNA
BD64_5089	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD64_5090	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BD64_5095	COG0535	radical SAM domain protein
BD64_5097	COG0387	Pfam Sodium calcium exchanger
BD64_5098	COG3871	stress protein (general stress protein 26)
BD64_5101	COG0586	Pfam SNARE associated Golgi protein
BD64_5104	COG0681	Belongs to the peptidase S26 family
BD64_5106	COG0697	spore germination
BD64_5107	COG2217	Heavy metal translocating P-type atpase
BD64_5108	COG1295	ribonuclease BN
BD64_5110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BD64_5113	COG3853	Toxic anion resistance protein (TelA)
BD64_5115	COG0861	Integral membrane protein TerC family
BD64_5116	COG2310	stress, protein
BD64_5117	COG2310	stress, protein
BD64_5118	COG2310	stress, protein
BD64_5121	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_5124	COG2270	Major facilitator Superfamily
BD64_5133	COG0488	(ABC) transporter
BD64_5134	COG1116	anion transmembrane transporter activity
BD64_5136	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_5139	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BD64_514	COG2824	Alkylphosphonate utilization operon protein PhnA
BD64_5145	COG1263	PTS System
BD64_5145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_5145	COG2190	(PTS) system
BD64_5146	COG0366	Alpha amylase catalytic
BD64_5147	COG0840	transmembrane signaling receptor activity
BD64_5148	COG0840	transmembrane signaling receptor activity
BD64_515	COG0390	transport system, permease component
BD64_5150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_5151	COG0765	amino acid transport
BD64_5153	COG0723	plastoquinol--plastocyanin reductase activity
BD64_5153	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_5154	COG2814	Major facilitator Superfamily
BD64_5155	COG3541	Predicted nucleotidyltransferase
BD64_5159	COG5002	protein histidine kinase activity
BD64_5165	COG0166	Belongs to the GPI family
BD64_5168	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_5169	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_517	COG1252	NADH dehydrogenase
BD64_5170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_5171	COG0235	Class ii aldolase
BD64_5173	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BD64_5174	COG0450	alkyl hydroperoxide reductase
BD64_5177	COG1473	amidohydrolase
BD64_5183	COG4807	Protein conserved in bacteria
BD64_5185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BD64_5186	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD64_5187	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_5190	COG2309	aminopeptidase activity
BD64_5191	COG2076	Multidrug Resistance protein
BD64_5192	COG1012	belongs to the aldehyde dehydrogenase family
BD64_5194	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BD64_5195	COG0546	phosphoglycolate phosphatase activity
BD64_5196	COG1597	lipid kinase activity
BD64_520	COG0316	Belongs to the HesB IscA family
BD64_5201	COG1846	Transcriptional regulator
BD64_5202	COG0003	Pfam Anion-transporting ATPase
BD64_5203	COG0003	Pfam Anion-transporting ATPase
BD64_5206	COG1464	Belongs to the NlpA lipoprotein family
BD64_5207	COG2011	ABC-type metal ion transport system permease component
BD64_5208	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_5209	COG1335	isochorismatase
BD64_5213	COG4851	CamS sex pheromone cAM373 precursor
BD64_5215	COG0210	DNA helicase
BD64_5220	COG0151	Belongs to the GarS family
BD64_5222	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BD64_5224	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BD64_5227	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BD64_5229	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BD64_523	COG1683	Conserved Protein
BD64_5230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BD64_5231	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BD64_5238	COG1215	transferase activity, transferring glycosyl groups
BD64_5244	COG2226	methyltransferase
BD64_5252	COG5002	protein histidine kinase activity
BD64_5254	COG2252	PERMEase
BD64_5258	COG1266	CAAX protease self-immunity
BD64_526	COG3708	Transcriptional regulator
BD64_5261	COG0488	(ABC) transporter
BD64_5262	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BD64_5263	COG0456	acetyltransferase
BD64_5264	COG1214	PFAM Peptidase M22, glycoprotease
BD64_5265	COG0802	atpase or kinase
BD64_5283	COG2183	response to ionizing radiation
BD64_5284	COG2337	Toxic component of a toxin-antitoxin (TA) module
BD64_5285	COG0864	Transcriptional regulator
BD64_5286	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BD64_5287	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BD64_5289	COG4294	response to UV
BD64_529	COG1252	NADH dehydrogenase
BD64_5290	COG0705	Rhomboid family
BD64_5290	COG0457	Tetratricopeptide repeat
BD64_5292	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BD64_5295	COG2814	Major facilitator Superfamily
BD64_5297	COG0179	Fumarylacetoacetate (FAA) hydrolase
BD64_5298	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BD64_53	COG0477	Major facilitator Superfamily
BD64_5304	COG0561	phosphatase activity
BD64_5305	COG0561	phosphatase activity
BD64_5306	COG4608	Belongs to the ABC transporter superfamily
BD64_5307	COG0444	Belongs to the ABC transporter superfamily
BD64_5309	COG0601	transmembrane transport
BD64_5310	COG0747	negative chemotaxis
BD64_5313	COG0488	(ABC) transporter
BD64_5317	COG5298	Protein conserved in bacteria
BD64_5318	COG0084	hydrolase, TatD family'
BD64_532	COG3584	3D domain protein
BD64_5321	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_5323	COG1609	Transcriptional regulator
BD64_5325	COG0204	Acyl-transferase
BD64_5328	COG0697	spore germination
BD64_5329	COG0583	DNA-binding transcription factor activity
BD64_5332	COG1910	domain protein
BD64_5333	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_5334	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_5335	COG4149	molybdate abc transporter
BD64_5338	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_5339	COG0656	L-ascorbic acid biosynthetic process
BD64_5340	COG4166	transmembrane transport
BD64_5341	COG4166	transmembrane transport
BD64_5344	COG2207	Transcriptional regulator
BD64_5346	COG4166	transmembrane transport
BD64_5347	COG4608	Belongs to the ABC transporter superfamily
BD64_5348	COG0444	Belongs to the ABC transporter superfamily
BD64_5349	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BD64_5350	COG0601	transmembrane transport
BD64_5353	COG2814	Major facilitator Superfamily
BD64_5355	COG2271	Major facilitator Superfamily
BD64_5356	COG0277	FAD linked oxidase domain protein
BD64_5359	COG1464	Belongs to the NlpA lipoprotein family
BD64_536	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BD64_5360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_5361	COG2011	ABC-type metal ion transport system permease component
BD64_5362	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_5370	COG1506	peptidase
BD64_5370	COG4946	Tricorn protease homolog
BD64_5370	COG0823	Involved in the tonB-independent uptake of proteins
BD64_5371	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BD64_5376	COG0596	Alpha beta hydrolase
BD64_5377	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BD64_5379	COG4856	YbbR-like protein
BD64_538	COG1268	BioY protein
BD64_5380	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BD64_5398	COG0726	polysaccharide deacetylase
BD64_5399	COG2194	sulfuric ester hydrolase activity
BD64_54	COG3279	Response regulator of the LytR AlgR family
BD64_540	COG2050	protein possibly involved in aromatic compounds catabolism
BD64_5401	COG0489	protein tyrosine kinase activity
BD64_5402	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_5406	COG0101	tRNA pseudouridine synthase activity
BD64_5407	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD64_5408	COG1122	ATPase activity
BD64_541	COG0423	glycine-tRNA ligase activity
BD64_5414	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BD64_5416	COG0024	Methionine aminopeptidase
BD64_5418	COG0201	protein transport
BD64_5423	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BD64_544	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_5444	COG1358	cellular component organization or biogenesis
BD64_5445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BD64_5447	COG2813	Specifically methylates the guanine in position
BD64_545	COG5018	Exonuclease
BD64_5452	COG0250	Participates in transcription elongation, termination and antitermination
BD64_5453	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BD64_5455	COG3688	RNA-binding protein containing a PIN domain
BD64_5456	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BD64_5459	COG1045	serine acetyltransferase
BD64_5463	COG4956	integral membrane protein (PIN domain superfamily)
BD64_5465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BD64_5466	COG0542	response to heat
BD64_5468	COG3880	PFAM UvrB UvrC protein
BD64_5475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BD64_5476	COG1396	sequence-specific DNA binding
BD64_5477	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BD64_5478	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BD64_5479	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BD64_5480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_5481	COG0512	Glutamine amidotransferase of anthranilate synthase
BD64_5482	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BD64_5483	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_5486	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD64_5488	COG0037	tRNA processing
BD64_5489	COG2208	phosphoserine phosphatase activity
BD64_549	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BD64_5492	COG1098	S1 RNA binding domain
BD64_5496	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BD64_5497	COG3956	TIGRFAM MazG family protein
BD64_5498	COG2244	polysaccharide biosynthetic process
BD64_5499	COG2002	toxin-antitoxin pair type II binding
BD64_55	COG1966	Carbon starvation protein
BD64_5500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BD64_5502	COG0193	aminoacyl-tRNA hydrolase activity
BD64_5503	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BD64_5506	COG0251	oxidation-reduction process
BD64_5507	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BD64_551	COG2267	carboxylic ester hydrolase activity
BD64_5510	COG4466	Protein conserved in bacteria
BD64_5513	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BD64_5514	COG0084	hydrolase, TatD family'
BD64_5515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_5515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_5516	COG2002	toxin-antitoxin pair type II binding
BD64_5517	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BD64_5519	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BD64_552	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD64_5521	COG1774	PSP1 C-terminal conserved region
BD64_5522	COG0470	DNA polymerase III
BD64_5524	COG1982	Orn Lys Arg decarboxylase major
BD64_553	COG1522	sequence-specific DNA binding
BD64_5536	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BD64_5537	COG0590	tRNA wobble adenosine to inosine editing
BD64_5538	COG1335	isochorismatase
BD64_5539	COG1428	Deoxynucleoside kinase
BD64_554	COG0436	Aminotransferase
BD64_5540	COG1428	Deoxynucleoside kinase
BD64_5546	COG1686	Belongs to the peptidase S11 family
BD64_5547	COG0516	GMP reductase activity
BD64_5547	COG0517	IMP dehydrogenase activity
BD64_555	COG1098	S1 RNA binding domain
BD64_5555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BD64_5556	COG0187	DNA topoisomerase II activity
BD64_5558	COG2501	S4 domain
BD64_5559	COG0592	DNA-directed DNA polymerase activity
BD64_556	COG2155	Conserved Protein
BD64_5563	COG0706	membrane insertase activity
BD64_5564	COG1847	R3H domain protein
BD64_5565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BD64_5569	COG1192	Involved in chromosome partitioning
BD64_557	COG0166	Belongs to the GPI family
BD64_5570	COG1475	DNA binding
BD64_5572	COG0668	transmembrane transport
BD64_5573	COG4481	Protein conserved in bacteria
BD64_5574	COG0012	GTP binding
BD64_5576	COG0629	single-stranded DNA binding
BD64_5578	COG4241	membrane
BD64_5579	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BD64_558	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BD64_5588	COG3344	reverse transcriptase
BD64_56	COG2879	small protein
BD64_560	COG1285	pathogenesis
BD64_5609	COG1923	regulation of RNA biosynthetic process
BD64_5611	COG0457	Tetratricopeptide repeat
BD64_5616	COG4974	Belongs to the 'phage' integrase family
BD64_5618	COG3443	Belongs to the bacterial solute-binding protein 9 family
BD64_5621	COG2801	Transposase and inactivated derivatives
BD64_5624	COG2801	Transposase and inactivated derivatives
BD64_5625	COG2801	Transposase and inactivated derivatives
BD64_5634	COG4974	Belongs to the 'phage' integrase family
BD64_5636	COG2002	toxin-antitoxin pair type II binding
BD64_5673	COG2801	Transposase and inactivated derivatives
BD64_5674	COG2801	Transposase and inactivated derivatives
BD64_5678	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BD64_5679	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BD64_568	COG0544	peptidyl-prolyl cis-trans isomerase activity
BD64_5682	COG0671	phosphoesterase, PA-phosphatase related
BD64_5683	COG4196	transglutaminase domain protein
BD64_5689	COG2311	Membrane
BD64_57	COG3706	GGDEF domain
BD64_5719	COG4962	Type ii secretion system protein e
BD64_5767	COG3344	reverse transcriptase
BD64_58	COG0351	phosphomethylpyrimidine kinase
BD64_587	COG0039	L-malate dehydrogenase activity
BD64_589	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BD64_59	COG4585	Histidine kinase
BD64_59	COG2203	Gaf domain
BD64_590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BD64_591	COG0297	glycogen (starch) synthase activity
BD64_592	COG0058	SHG alpha-glucan phosphorylase activity
BD64_596	COG1278	Cold shock
BD64_597	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BD64_598	COG1575	Belongs to the MenA family. Type 1 subfamily
BD64_599	COG1169	isochorismate synthase
BD64_60	COG4585	Histidine kinase
BD64_60	COG2203	Gaf domain
BD64_600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BD64_601	COG0596	Alpha beta hydrolase
BD64_602	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BD64_604	COG4948	Mandelate Racemase Muconate Lactonizing
BD64_61	COG2197	response regulator
BD64_610	COG3964	amidohydrolase
BD64_617	COG0577	efflux transmembrane transporter activity
BD64_618	COG0577	efflux transmembrane transporter activity
BD64_619	COG1136	(ABC) transporter
BD64_620	COG0577	efflux transmembrane transporter activity
BD64_621	COG0577	efflux transmembrane transporter activity
BD64_623	COG0577	efflux transmembrane transporter activity
BD64_624	COG2205	protein histidine kinase activity
BD64_625	COG0745	RESPONSE REGULATOR receiver
BD64_626	COG3708	Transcriptional regulator
BD64_626	COG2207	Transcriptional regulator
BD64_627	COG1136	(ABC) transporter
BD64_628	COG0577	efflux transmembrane transporter activity
BD64_63	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BD64_630	COG0586	Pfam SNARE associated Golgi protein
BD64_637	COG1597	lipid kinase activity
BD64_64	COG1011	Hydrolase
BD64_643	COG0745	RESPONSE REGULATOR receiver
BD64_644	COG5002	protein histidine kinase activity
BD64_651	COG1842	Phage shock protein A
BD64_656	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_660	COG1294	oxidase, subunit
BD64_661	COG1271	oxidase subunit
BD64_663	COG0288	reversible hydration of carbon dioxide
BD64_668	COG0494	nUDIX hydrolase
BD64_670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BD64_674	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_675	COG1116	anion transmembrane transporter activity
BD64_676	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_68	COG0460	homoserine dehydrogenase
BD64_680	COG1368	sulfuric ester hydrolase activity
BD64_681	COG2267	carboxylic ester hydrolase activity
BD64_682	COG4191	Histidine kinase
BD64_683	COG5002	protein histidine kinase activity
BD64_684	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BD64_694	COG0521	Mo-molybdopterin cofactor biosynthetic process
BD64_696	COG0438	transferase activity, transferring glycosyl groups
BD64_697	COG0671	phosphoesterase, PA-phosphatase related
BD64_698	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BD64_699	COG2267	carboxylic ester hydrolase activity
BD64_7	COG0745	RESPONSE REGULATOR receiver
BD64_70	COG1609	Transcriptional regulator
BD64_703	COG1794	racemase activity, acting on amino acids and derivatives
BD64_705	COG1131	(ABC) transporter
BD64_706	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BD64_707	COG1242	4 iron, 4 sulfur cluster binding
BD64_71	COG2755	lipolytic protein G-D-S-L family
BD64_711	COG1136	(ABC) transporter
BD64_713	COG0582	viral genome integration into host DNA
BD64_714	COG0490	domain, Protein
BD64_715	COG0475	glutathione-regulated potassium exporter activity
BD64_716	COG2814	Major facilitator Superfamily
BD64_72	COG1131	(ABC) transporter
BD64_724	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BD64_726	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_73	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD64_731	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_733	COG0303	'Molybdopterin
BD64_734	COG1763	Mo-molybdopterin cofactor biosynthetic process
BD64_735	COG0314	molybdopterin synthase activity
BD64_738	COG4975	Glucose uptake
BD64_740	COG1329	Transcriptional regulator
BD64_744	COG3832	glyoxalase III activity
BD64_746	COG2814	Major facilitator Superfamily
BD64_747	COG2081	HI0933 family
BD64_748	COG2244	polysaccharide biosynthetic process
BD64_749	COG1187	pseudouridine synthase activity
BD64_75	COG2814	Major facilitator Superfamily
BD64_750	COG1349	DNA-binding transcription factor activity
BD64_751	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_752	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_754	COG1523	belongs to the glycosyl hydrolase 13 family
BD64_755	COG0510	thiamine kinase activity
BD64_758	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_76	COG0561	phosphatase activity
BD64_760	COG1363	Peptidase, m42
BD64_761	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BD64_762	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_763	COG4848	Belongs to the UPF0354 family
BD64_764	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_766	COG1674	ftsk spoiiie
BD64_769	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_77	COG2233	PERMEase
BD64_773	COG2309	aminopeptidase activity
BD64_775	COG3118	belongs to the thioredoxin family
BD64_776	COG4851	CamS sex pheromone cAM373 precursor
BD64_777	COG1609	Transcriptional regulator
BD64_78	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BD64_784	COG0666	response to abiotic stimulus
BD64_786	COG0745	RESPONSE REGULATOR receiver
BD64_788	COG0123	including yeast histone deacetylase and acetoin utilization protein
BD64_789	COG0517	IMP dehydrogenase activity
BD64_790	COG0454	-acetyltransferase
BD64_791	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_793	COG1595	DNA-templated transcription, initiation
BD64_795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BD64_799	COG0626	cystathionine gamma-synthase activity
BD64_8	COG5002	protein histidine kinase activity
BD64_80	COG2363	Small membrane protein
BD64_800	COG1956	GAF domain-containing protein
BD64_801	COG1309	transcriptional regulator
BD64_802	COG1309	transcriptional regulator
BD64_803	COG0697	spore germination
BD64_804	COG0583	DNA-binding transcription factor activity
BD64_806	COG1104	cysteine desulfurase activity
BD64_809	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_811	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BD64_812	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BD64_814	COG3874	Sporulation protein YtfJ
BD64_815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BD64_816	COG0827	DNA restriction-modification system
BD64_817	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BD64_82	COG3773	Cell wall hydrolase
BD64_821	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_830	COG0589	response to stress
BD64_831	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_834	COG1476	TRANSCRIPTIONal
BD64_836	COG0662	Cupin 2, conserved barrel domain protein
BD64_837	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_844	COG0006	proline dipeptidase activity
BD64_847	COG4109	DRTGG domain
BD64_85	COG0280	phosphate acetyltransferase
BD64_851	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BD64_854	COG0587	DNA-directed DNA polymerase activity
BD64_855	COG0281	malic enzyme
BD64_856	COG1725	Transcriptional regulator
BD64_86	COG0095	Lipoate-protein ligase
BD64_861	COG3030	protein affecting phage T7 exclusion by the F plasmid
BD64_862	COG0628	permease
BD64_864	COG0372	Belongs to the citrate synthase family
BD64_865	COG0538	isocitrate dehydrogenase activity
BD64_869	COG0745	RESPONSE REGULATOR receiver
BD64_870	COG5002	protein histidine kinase activity
BD64_871	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_871	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_872	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BD64_873	COG1971	Probably functions as a manganese efflux pump
BD64_874	COG0237	dephospho-CoA kinase activity
BD64_875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BD64_876	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BD64_878	COG3611	Membrane attachment protein
BD64_879	COG1484	DNA-dependent DNA replication
BD64_881	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_882	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BD64_886	COG1363	Peptidase, m42
BD64_887	COG1309	transcriptional regulator
BD64_888	COG1566	PFAM secretion protein HlyD family protein
BD64_889	COG2814	Major facilitator Superfamily
BD64_894	COG1418	mRNA catabolic process
BD64_896	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BD64_898	COG0072	phenylalanine-tRNA ligase activity
BD64_898	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_899	COG0017	Asparaginyl-tRNA synthetase
BD64_9	COG4863	YycH protein
BD64_90	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_905	COG1286	toxin biosynthetic process
BD64_906	COG1796	DNA polymerase
BD64_906	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BD64_909	COG1187	pseudouridine synthase activity
BD64_91	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_910	COG1114	Component of the transport system for branched-chain amino acids
BD64_911	COG5386	Cell surface protein
BD64_913	COG5386	Cell surface protein
BD64_916	COG1120	ATPase activity
BD64_917	COG4509	Sortase family
BD64_92	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BD64_921	COG4895	conserved protein (DUF2196)
BD64_923	COG0745	RESPONSE REGULATOR receiver
BD64_924	COG2205	protein histidine kinase activity
BD64_925	COG1131	(ABC) transporter
BD64_93	COG1120	ATPase activity
BD64_931	COG2318	DinB family
BD64_936	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_937	COG1309	transcriptional regulator
BD64_938	COG1024	Enoyl-CoA hydratase
BD64_939	COG2086	electron transfer activity
BD64_94	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_940	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BD64_941	COG3118	belongs to the thioredoxin family
BD64_943	COG1719	4-vinyl reductase, 4VR
BD64_944	COG2009	succinate dehydrogenase
BD64_945	COG1053	succinate dehydrogenase
BD64_946	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BD64_947	COG0824	Thioesterase
BD64_948	COG1876	peptidase activity
BD64_949	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BD64_95	COG1078	dGTPase activity
BD64_950	COG1360	Flagellar Motor Protein
BD64_951	COG1360	Flagellar Motor Protein
BD64_952	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BD64_953	COG4152	abc transporter atp-binding protein
BD64_954	COG1668	transmembrane transport
BD64_955	COG1959	2 iron, 2 sulfur cluster binding
BD64_957	COG0697	spore germination
BD64_958	COG1396	sequence-specific DNA binding
BD64_959	COG1983	PspC domain protein
BD64_962	COG3279	Response regulator of the LytR AlgR family
BD64_963	COG3275	phosphorelay sensor kinase activity
BD64_964	COG4608	Belongs to the ABC transporter superfamily
BD64_965	COG0444	Belongs to the ABC transporter superfamily
BD64_969	COG0402	S-adenosylhomocysteine deaminase activity
BD64_97	COG1994	Peptidase M50
BD64_970	COG0402	S-adenosylhomocysteine deaminase activity
BD64_972	COG2233	PERMEase
BD64_973	COG2197	response regulator
BD64_976	COG1309	transcriptional regulator
BD64_980	COG5401	PFAM Sporulation and spore germination
BD64_982	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BD64_983	COG0622	Phosphoesterase
BD64_99	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_993	COG1067	ATP-dependent peptidase activity
BD64_993	COG0470	DNA polymerase III
BD64_996	COG1764	response to oxidative stress
BD64_997	COG1846	Transcriptional regulator
BD64_999	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes