locus-tag class description BAPCR_00004 ENOG4105ZU5 s-layer protein BAPCR_00005 ENOG4107QP3 malate synthase g BAPCR_00008 ENOG4105VEQ Cold shock protein BAPCR_00011 ENOG4105XVF Competence transcription factor BAPCR_00014 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAPCR_00015 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAPCR_00023 ENOG4105ERH Fumarylacetoacetate hydrolase BAPCR_00028 ENOG4105CAQ asparagine synthetase BAPCR_00029 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAPCR_00030 ENOG4105CH6 catalase BAPCR_00031 ENOG4105BZU Histidine kinase BAPCR_00036 ENOG4105QNR S1 RNA binding domain protein BAPCR_00038 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPCR_00040 ENOG4107AYK membrAne BAPCR_00041 ENOG41073B9 BAPCR_00043 ENOG4108KP7 hydrolase BAPCR_00045 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAPCR_00050 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPCR_00051 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAPCR_00054 ENOG4105C31 Tryptophanyl-tRNA synthetase BAPCR_00057 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPCR_00058 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPCR_00060 ENOG4108JQ7 (ABC) transporter BAPCR_00061 ENOG4105UQX Mate efflux family protein BAPCR_00065 ENOG4108ZCF integral membrane protein BAPCR_00067 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPCR_00069 ENOG4105DPN Oligoendopeptidase f BAPCR_00072 ENOG4108Z18 K06886 hemoglobin BAPCR_00073 ENOG4105MIX Adenylate cyclase BAPCR_00076 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAPCR_00077 ENOG4105EMS pseudouridine synthase BAPCR_00080 ENOG4105CNI cell division protein FtsW BAPCR_00082 ENOG4105K64 Glycosyl transferase, family 2 BAPCR_00086 ENOG4107TVC Glycosyl transferase, family 2 BAPCR_00091 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAPCR_00092 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BAPCR_00094 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAPCR_00103 ENOG4108WVJ 2'-5' rna ligase BAPCR_00108 ENOG4105CK7 Sodium proline symporter BAPCR_00109 ENOG4105CRQ synthase (Component I) BAPCR_00110 ENOG4105DDQ anthranilate synthase BAPCR_00128 ENOG4105C7S Dehydrogenase BAPCR_00130 ENOG4105VZ8 Transcriptional regulator BAPCR_00141 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BAPCR_00143 ENOG4105DZ1 carboxypeptidase BAPCR_00144 ENOG4105VFR signal peptidase BAPCR_00150 ENOG4105C26 Dehydrogenase BAPCR_00151 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_00152 ENOG4105F38 ABC transporter, permease BAPCR_00153 ENOG4105D38 putrescine abc transporter BAPCR_00154 ENOG4107RUE extracellular solute-binding protein family 1 BAPCR_00156 ENOG4105EYF MMPL domain protein BAPCR_00158 ENOG4108YBP pseudouridine synthase BAPCR_00160 ENOG4105K4I Scp-like extracellular BAPCR_00161 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAPCR_00162 ENOG4105CQB FAD linked oxidase domain protein BAPCR_00165 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_00166 ENOG4105BZU Histidine kinase BAPCR_00167 ENOG4105JXH GntR family transcriptional regulator BAPCR_00171 ENOG4106A3R peptidase BAPCR_00173 ENOG4108QTI )-transporter BAPCR_00174 ENOG4107TS3 membrane protein, TerC BAPCR_00176 ENOG4105CZN Potassium uptake protein BAPCR_00177 ENOG410681C small acid-soluble spore protein BAPCR_00178 ENOG4108Z7G MaoC domain protein dehydratase BAPCR_00182 ENOG4105CHR reductase BAPCR_00184 ENOG4105MWK D-amino acid dehydrogenase, small subunit BAPCR_00188 ENOG4105C4Y ABC transporter BAPCR_00190 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_00193 ENOG4107RCV ABC transporter, permease BAPCR_00194 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BAPCR_00198 ENOG4105E98 transcriptional regulator DeoR family BAPCR_00203 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAPCR_00204 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAPCR_00206 ENOG4105PXI polysaccharide deacetylase BAPCR_00208 ENOG4105BZU Histidine kinase BAPCR_00209 ENOG41090MY MarR family Transcriptional regulator BAPCR_00211 ENOG4106DF1 BAPCR_00213 ENOG4105BZU Histidine kinase BAPCR_00215 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BAPCR_00216 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAPCR_00225 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BAPCR_00226 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPCR_00228 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPCR_00229 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPCR_00230 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAPCR_00231 ENOG4105CZV ABC transporter BAPCR_00233 ENOG4105CJ1 ABC, transporter BAPCR_00241 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAPCR_00242 ENOG4105EA8 2-Nitropropane dioxygenase BAPCR_00243 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAPCR_00245 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPCR_00250 ENOG4105NQC Flavodoxin BAPCR_00257 ENOG4107QMU Mate efflux family protein BAPCR_00258 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPCR_00264 ENOG4105CZN Potassium uptake protein BAPCR_00265 ENOG41063Y9 BAPCR_00266 ENOG4105KBJ sporulation protein ytfj BAPCR_00271 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAPCR_00272 ENOG4105C7K acetolactate synthase BAPCR_00273 ENOG4108ZP8 Acetolactate synthase small subunit BAPCR_00274 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAPCR_00276 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAPCR_00281 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAPCR_00288 ENOG4107RVV histidinol phosphate phosphatase, hisj family BAPCR_00291 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAPCR_00292 ENOG4105E0M Sulfatase BAPCR_00294 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAPCR_00298 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAPCR_00299 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAPCR_00301 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAPCR_00302 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAPCR_00303 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAPCR_00304 ENOG4105C8J )-transporter BAPCR_00308 ENOG4105DFD Na H antiporter BAPCR_00312 ENOG4105ENE Histidine kinase BAPCR_00313 ENOG4105WH1 Two component transcriptional regulator luxr family BAPCR_00317 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BAPCR_00322 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAPCR_00326 ENOG4105CJ3 phosphate transporter BAPCR_00327 ENOG4107GRR phosphate transport regulator BAPCR_00328 ENOG4105BZ4 penicillin-binding protein BAPCR_00331 ENOG4105BZU Histidine kinase BAPCR_00332 ENOG4105I3N Conserved Protein BAPCR_00335 ENOG4105BZU Histidine kinase BAPCR_00342 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPCR_00343 ENOG4105DZ1 carboxypeptidase BAPCR_00344 ENOG4108JIC nucleoside recognition domain protein BAPCR_00346 ENOG4105FE9 pseudouridine synthase BAPCR_00348 ENOG4107TWT Cytochrome c biogenesis protein BAPCR_00349 ENOG4105CRE cytochrome C BAPCR_00350 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_00351 ENOG4105BZU Histidine kinase BAPCR_00352 ENOG4108WBT adenosyltransferase BAPCR_00355 ENOG4108SAX Membrane BAPCR_00357 ENOG4105T7X BAPCR_00358 ENOG4105C9U ATP-dependent DNA helicase RecQ BAPCR_00359 ENOG4105I7S Abortive infection protein BAPCR_00361 ENOG4107RGJ metallophosphoesterase BAPCR_00362 ENOG4107X2D transcriptional regulator, merr family BAPCR_00363 ENOG4108S6Z Negative regulator of genetic competence BAPCR_00368 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAPCR_00369 ENOG4107RB3 L-asparaginase BAPCR_00376 ENOG4105S2F BAPCR_00377 ENOG41065D1 BAPCR_00383 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAPCR_00386 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAPCR_00388 ENOG4105EAH synthase BAPCR_00392 ENOG4105CIH Imidazole acetol-phosphate transaminase BAPCR_00393 ENOG41068YB TPR repeat-containing protein BAPCR_00396 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BAPCR_00397 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAPCR_00398 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BAPCR_00404 ENOG4108JYZ YitT family BAPCR_00405 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAPCR_00408 ENOG4105FJR Lmbe family BAPCR_00409 ENOG4105CPK Glycosyl transferase (Group 1 BAPCR_00416 ENOG4105DVT helicase BAPCR_00417 ENOG4105DVT helicase BAPCR_00418 ENOG4105YAC BAPCR_00422 ENOG4105CSM endonuclease III BAPCR_00424 ENOG4105BZ4 penicillin-binding protein BAPCR_00435 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAPCR_00437 ENOG4105DVT helicase BAPCR_00438 ENOG4105CTD carboxy-peptidase BAPCR_00441 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAPCR_00443 ENOG4105C2W permease BAPCR_00444 ENOG4105DHF Membrane BAPCR_00446 ENOG410890F Dynamin family BAPCR_00447 ENOG410890F Dynamin family BAPCR_00449 ENOG4108W0I acetyltransferase BAPCR_00451 ENOG4105KHC sulfurtransferase BAPCR_00454 ENOG4106032 Glutathionylspermidine synthase BAPCR_00468 ENOG4105CPK Glycosyl transferase (Group 1 BAPCR_00472 ENOG4108SZE gCN5-related N-acetyltransferase BAPCR_00476 ENOG41081VK Ribonuclease BAPCR_00489 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPCR_00491 ENOG4107RWR Sodium hydrogen exchanger BAPCR_00492 ENOG4105CN5 Metallo-Beta-Lactamase BAPCR_00493 ENOG4108Z5V transcriptional regulator, merr family BAPCR_00495 ENOG4105H67 Protein of unknown function (DUF421) BAPCR_00496 ENOG41080C8 DUF218 domain BAPCR_00507 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAPCR_00509 ENOG4107R0U MotA TolQ exbB proton channel BAPCR_00510 ENOG4105ER2 Ompa motb domain protein BAPCR_00511 ENOG4107YTP response regulator receiver protein BAPCR_00512 ENOG4105CBS Chea signal transduction histidine kinase BAPCR_00513 ENOG4105CBS Chea signal transduction histidine kinase BAPCR_00514 ENOG4105DD5 Flagellar motor switch protein BAPCR_00517 ENOG4105BZU Histidine kinase BAPCR_00522 ENOG4105E1Q flagellar hook-associated protein BAPCR_00523 ENOG4105DTJ flagellar hook-associated protein BAPCR_00528 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAPCR_00529 ENOG4108ZC9 flagellar basal-body rod protein flgc BAPCR_00530 ENOG41075Z6 flagellar hook-basal body complex protein fliE BAPCR_00531 ENOG4107U2N Flagellar M-ring protein BAPCR_00533 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAPCR_00540 ENOG4105BZE flagellar hook protein, FlgE BAPCR_00544 ENOG4107R88 Chemotaxis protein (CheV) BAPCR_00546 ENOG4105K64 Glycosyl transferase, family 2 BAPCR_00552 ENOG4107TVC Glycosyl transferase, family 2 BAPCR_00557 ENOG4105I03 Flagellin BAPCR_00558 ENOG4105E4C Lytic transglycosylase catalytic BAPCR_00559 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAPCR_00561 ENOG4105DD5 Flagellar motor switch protein BAPCR_00563 ENOG4105CN7 Flagellar biosynthetic protein FliP BAPCR_00564 ENOG4105VS8 Flagellar biosynthetic protein fliq BAPCR_00566 ENOG4105D00 flagellar biosynthetic protein flhB BAPCR_00567 ENOG4105D7B Flagellar biosynthesis protein flha BAPCR_00568 ENOG4105FZW flagellar biosynthesis regulator FlhF BAPCR_00569 ENOG4105KTQ flagellar basal-body rod protein BAPCR_00570 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPCR_00575 ENOG4108RZE Tetr family transcriptional regulator BAPCR_00579 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAPCR_00584 ENOG4105DUM transcriptional regulator, lysR family BAPCR_00585 ENOG4108KB2 LysR family Transcriptional regulator BAPCR_00586 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_00587 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAPCR_00588 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BAPCR_00589 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAPCR_00596 ENOG4105CVJ phosphoglycerate mutase BAPCR_00603 ENOG4105CAQ asparagine synthetase BAPCR_00607 ENOG4105PGM cation diffusion facilitator family transporter BAPCR_00609 ENOG4105DRR Transcriptional regulator, GntR family BAPCR_00610 ENOG4108UZ3 Transporter BAPCR_00611 ENOG4105CKI cobalamin synthesis protein BAPCR_00612 ENOG4108PJD permease BAPCR_00615 ENOG4105DFD Na H antiporter BAPCR_00616 ENOG4105C9Q fumarate hydratase class II BAPCR_00620 ENOG4107QJQ Mate efflux family protein BAPCR_00621 ENOG4107QJQ Mate efflux family protein BAPCR_00622 ENOG4105EC3 peptidase S51, dipeptidase E BAPCR_00626 ENOG4107QIV Cytochrome c biogenesis protein BAPCR_00633 ENOG4106BRA Membrane BAPCR_00640 ENOG4105CJ1 ABC, transporter BAPCR_00644 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAPCR_00646 ENOG4108IJ0 Aspartate ammonia-lyase BAPCR_00647 ENOG4105C6K Malic enzyme BAPCR_00661 ENOG4105FVX BAPCR_00670 ENOG4105CSR polyphosphate kinase 2 BAPCR_00671 ENOG4105DXI Major Facilitator superfamily BAPCR_00674 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAPCR_00676 ENOG4105EU0 Major facilitator Superfamily BAPCR_00677 ENOG4105C6T cysteine synthase BAPCR_00678 ENOG4105C6T cysteine synthase BAPCR_00682 ENOG4105C8J )-transporter BAPCR_00684 ENOG4105X5K response regulator receiver protein BAPCR_00685 ENOG4105H67 Protein of unknown function (DUF421) BAPCR_00689 ENOG4106KE4 Dehydrogenase BAPCR_00693 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAPCR_00694 ENOG4105CHR reductase BAPCR_00695 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAPCR_00696 ENOG4105C7K acetolactate synthase BAPCR_00697 ENOG4108ZP8 Acetolactate synthase small subunit BAPCR_00698 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAPCR_00700 ENOG4105C7B Threonine dehydratase BAPCR_00702 ENOG4105PNM synthesis protein BAPCR_00708 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BAPCR_00710 ENOG4105DY9 regulatoR BAPCR_00711 ENOG4105CYC Transferase BAPCR_00715 ENOG4105F6J Alpha beta hydrolase fold BAPCR_00716 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPCR_00722 ENOG41068WN BAPCR_00726 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAPCR_00727 ENOG4105C72 UPF0176 protein BAPCR_00729 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAPCR_00731 ENOG4105C0X amino acid BAPCR_00732 ENOG4105C0X amino acid BAPCR_00737 ENOG4107RHR regulatoR BAPCR_00739 ENOG4105D9N nucleoside BAPCR_00740 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAPCR_00746 ENOG4107RAQ aminopeptidase BAPCR_00747 ENOG4107STQ Multicopper oxidase BAPCR_00757 ENOG4108T5E Copper resistance protein BAPCR_00758 ENOG4105KTB nuclear export factor GLE1 BAPCR_00760 ENOG4107RT3 EamA-like transporter family BAPCR_00761 ENOG4105GZI Transcriptional regulator BAPCR_00762 ENOG4108Z40 Transcriptional regulator BAPCR_00763 ENOG4107ZXU DSBA oxidoreductase BAPCR_00764 ENOG4108TVJ Nitroreductase BAPCR_00766 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAPCR_00767 ENOG4106F5Q Membrane BAPCR_00768 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPCR_00770 ENOG4105CKI cobalamin synthesis protein BAPCR_00774 ENOG4108Z7G MaoC domain protein dehydratase BAPCR_00775 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPCR_00777 ENOG4105C0Z ABC transporter BAPCR_00778 ENOG4108IV0 ABC, transporter BAPCR_00779 ENOG4105C32 Amino acid ABC transporter (Permease) BAPCR_00781 ENOG4105SKE transcriptional Regulator LysR family BAPCR_00785 ENOG4105YGB Transcriptional regulator BAPCR_00787 ENOG4105C4M (Ubiquinol oxidase) subunit I BAPCR_00788 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAPCR_00789 ENOG4108JJ9 ABC, transporter BAPCR_00790 ENOG4108JJ8 (ABC) transporter BAPCR_00798 ENOG4105BZ1 (ABC) transporter BAPCR_00799 ENOG4105BZ1 (ABC) transporter BAPCR_00800 ENOG4105EFI regulatoR BAPCR_00802 ENOG4105BZU Histidine kinase BAPCR_00805 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAPCR_00806 ENOG4108ZJ4 polysaccharide deacetylase BAPCR_00810 ENOG4105D6E homoserine dehydrogenase BAPCR_00815 ENOG4108KGH TRANSCRIPTIONal BAPCR_00817 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_00818 ENOG4105BZU Histidine kinase BAPCR_00819 ENOG4107VMI polysaccharide deacetylase BAPCR_00821 ENOG4105KT7 mgtC SapB transporter BAPCR_00822 ENOG4105VRR gCN5-related N-acetyltransferase BAPCR_00824 ENOG4105DUU IucA IucC family protein BAPCR_00825 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_00828 ENOG4108WBH protein TIM barrel BAPCR_00829 ENOG4108WBH protein TIM barrel BAPCR_00830 ENOG4105YWU small acid-soluble spore protein BAPCR_00832 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAPCR_00842 ENOG4105KRN Transcriptional regulator, abrb family BAPCR_00844 ENOG4105YVS arsR family transcriptional regulator BAPCR_00845 ENOG4107SET aldo keto reductase BAPCR_00846 ENOG4107XZQ multidrug resistance protein BAPCR_00851 ENOG4105C8Q Methyl-accepting chemotaxis BAPCR_00854 ENOG4108K88 Membrane BAPCR_00855 ENOG4108WPJ Ferritin-like domain BAPCR_00858 ENOG4105DEN Luciferase family BAPCR_00862 ENOG4107QM2 Aldo Keto reductase BAPCR_00863 ENOG4105CKI cobalamin synthesis protein BAPCR_00874 ENOG4105DSE periplasmic solute binding protein BAPCR_00876 ENOG4105K4T epimerase BAPCR_00878 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAPCR_00883 ENOG4105CVJ phosphoglycerate mutase BAPCR_00887 ENOG4107T5V SNARE associated Golgi BAPCR_00890 ENOG4108PJD permease BAPCR_00892 ENOG4108S4H thioesterase Superfamily protein BAPCR_00893 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPCR_00897 ENOG4105SXS Protein of unknown function (DUF456) BAPCR_00898 ENOG4105C37 (CBS) domain BAPCR_00902 ENOG4108Z7R Chaperone CsaA BAPCR_00906 ENOG4108ZRV stage ii sporulation protein p BAPCR_00908 ENOG4108VXD carboxy-peptidase BAPCR_00910 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAPCR_00915 ENOG4108X4Q Hydrolase BAPCR_00917 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAPCR_00918 ENOG4107RBS Methyltransferase BAPCR_00921 ENOG41087PP glycosyltransferase MGT family BAPCR_00922 ENOG4108JYZ YitT family BAPCR_00923 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAPCR_00929 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAPCR_00938 ENOG4105KBJ sporulation protein ytfj BAPCR_00943 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAPCR_00948 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAPCR_00949 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_00951 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BAPCR_00952 ENOG4105EMN RNA polymerase sigma factor BAPCR_00957 ENOG4108V06 Glutathione peroxidase BAPCR_00960 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPCR_00964 ENOG4108IUE nitrate reductase beta subunit BAPCR_00965 ENOG4105R3A Nitrate reductase BAPCR_00970 ENOG4107V6Q Cyclic nucleotide-binding domain BAPCR_00971 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAPCR_00972 ENOG4105D06 uba thif-type nad fad binding protein BAPCR_00973 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPCR_00974 ENOG4108ZAF Molybdopterin BAPCR_00979 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAPCR_00980 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAPCR_00981 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAPCR_00982 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAPCR_00983 ENOG4108IFG nitrite reductase, (NAD(P)H) BAPCR_00984 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BAPCR_00992 ENOG4105MCT stage V sporulation protein S BAPCR_00995 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPCR_00999 ENOG4105C5H ABC transporter BAPCR_01002 ENOG4108UUM single-stranded DNA-binding protein BAPCR_01004 ENOG41061H0 Monooxygenase BAPCR_01008 ENOG4107YX5 Pfam:DUF548 BAPCR_01009 ENOG4105C75 arginyL-tRNA synthetase BAPCR_01016 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAPCR_01019 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAPCR_01020 ENOG4105C5S asparaginyl-tRNA synthetase BAPCR_01024 ENOG4105EC2 ftsk spoIIIe BAPCR_01042 ENOG4105BZW Glycerate kinase BAPCR_01043 ENOG4107QPK )-transporter BAPCR_01044 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_01045 ENOG41062D9 Histidine kinase BAPCR_01048 ENOG4105C8J )-transporter BAPCR_01052 ENOG4107XGZ Hydrolase BAPCR_01053 ENOG4105CY2 Citrate transporter BAPCR_01054 ENOG4105C0A alcohol dehydrogenase BAPCR_01057 ENOG4105KD7 acetyltransferase BAPCR_01059 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BAPCR_01064 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BAPCR_01068 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BAPCR_01071 ENOG4107RVG penicillin-binding protein BAPCR_01072 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAPCR_01073 ENOG4105E9Q Acyl-transferase BAPCR_01074 ENOG4108UT2 hemolysin iii BAPCR_01076 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAPCR_01078 ENOG4108RCR degv family BAPCR_01079 ENOG4105E8R UPF0173 metal-dependent hydrolase BAPCR_01080 ENOG4108KF3 Electron transport protein SCO1 SenC BAPCR_01081 ENOG4107Y70 Heat shock protein BAPCR_01082 ENOG4105CAQ asparagine synthetase BAPCR_01086 ENOG4108MES Periplasmic binding protein BAPCR_01087 ENOG4105F0I Aminotransferase BAPCR_01094 ENOG4105D8X mechanosensitive ion channel BAPCR_01095 ENOG4105BZU Histidine kinase BAPCR_01096 ENOG4105WH1 Two component transcriptional regulator luxr family BAPCR_01098 ENOG4106KNT transcriptional regulator BAPCR_01105 ENOG4105CMG Carbohydrate kinase BAPCR_01106 ENOG4105CMG Carbohydrate kinase BAPCR_01112 ENOG4108IJ8 ABC transporter BAPCR_01113 ENOG4105E90 ABC transporter BAPCR_01114 ENOG4105D5Q Arginine ornithine antiporter BAPCR_01121 ENOG4105C37 (CBS) domain BAPCR_01126 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPCR_01130 ENOG4107S4Y M20 DapE family protein YgeY BAPCR_01131 ENOG4108TSC N-acetyltransferase BAPCR_01132 ENOG4108JUB Transcriptional regulator BAPCR_01133 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAPCR_01141 ENOG4108N23 SpoOM-related protein BAPCR_01142 ENOG410841Q phosphoesterase PA-phosphatase related protein BAPCR_01144 ENOG4105SZ6 Thioredoxin BAPCR_01146 ENOG4108IBT Inherit from COG: transposase BAPCR_01165 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPCR_01173 ENOG4105BZ4 penicillin-binding protein BAPCR_01174 ENOG4105CZM Major Facilitator BAPCR_01175 ENOG4105W8X HesB YadR YfhF-family protein BAPCR_01177 ENOG4105DXD 2-methylcitrate dehydratase BAPCR_01178 ENOG4105CR4 methylisocitrate lyase BAPCR_01179 ENOG4105C1G acyl-Coa dehydrogenase BAPCR_01180 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPCR_01182 ENOG4105N14 lysine exporter protein LysE YggA BAPCR_01183 ENOG4105E39 Enoyl-CoA hydratase BAPCR_01186 ENOG4107RFY SbcCD D subunit BAPCR_01187 ENOG4105EYH Exonuclease BAPCR_01191 ENOG4105FCD Major Facilitator BAPCR_01192 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAPCR_01193 ENOG4105E4F Isochorismate synthase BAPCR_01194 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAPCR_01195 ENOG4105WQI isochorismatase BAPCR_01196 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_01197 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_01198 ENOG4105WQT MbtH domain protein BAPCR_01199 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_01202 ENOG4105K70 DNA-binding protein BAPCR_01206 ENOG4105BZG amino acid carrier protein BAPCR_01207 ENOG4105BZG amino acid carrier protein BAPCR_01211 ENOG4105FE9 pseudouridine synthase BAPCR_01212 ENOG4105C22 threonyL-tRNA synthetase BAPCR_01213 ENOG4105C19 ABC transporter BAPCR_01216 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAPCR_01222 ENOG4108D32 Methyltransferase BAPCR_01228 ENOG41081I9 integral membrane protein BAPCR_01234 ENOG4105EYF MMPL domain protein BAPCR_01239 ENOG4105WCN acetyltransferase BAPCR_01245 ENOG4105C1Q protoporphyrinogen oxidase BAPCR_01247 ENOG41068WN BAPCR_01249 ENOG4105VEQ Cold shock protein BAPCR_01253 ENOG410667J hydrolase BAPCR_01261 ENOG4107V2S Transcriptional regulator BAPCR_01262 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAPCR_01265 ENOG4105DND Transcriptional regulator BAPCR_01266 ENOG4108RPX mosc domain containing protein BAPCR_01269 ENOG4105BZ1 (ABC) transporter BAPCR_01270 ENOG4105BZ1 (ABC) transporter BAPCR_01274 ENOG4108JCI Transcriptional regulator BAPCR_01280 ENOG4108KPJ rna polymerase sigma factor BAPCR_01285 ENOG4105F32 YngK protein BAPCR_01290 ENOG4105RD7 BadF BadG BcrA BcrD BAPCR_01292 ENOG4107STF Involved in phosphonate degradation (By similarity) BAPCR_01296 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAPCR_01299 ENOG4105C1J atp-dependent rna helicase BAPCR_01301 ENOG4108RZE Tetr family transcriptional regulator BAPCR_01306 ENOG41088CC tellurite resistance protein tehB BAPCR_01308 ENOG4108I0C methyltransferase BAPCR_01309 ENOG4107RA9 decarboxylase BAPCR_01310 ENOG41090HR transcriptional regulator BAPCR_01318 ENOG4105CIN aminoacyl-histidine dipeptidase BAPCR_01325 ENOG4107RF6 penicillin-binding protein BAPCR_01326 ENOG4107RF6 penicillin-binding protein BAPCR_01328 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAPCR_01329 ENOG4105ETE Transcriptional regulator (LacI family BAPCR_01330 ENOG4105IE8 Alpha-ketoglutarate permease BAPCR_01331 ENOG4105CK5 oxidoreductase BAPCR_01337 ENOG4105D2N Aldolase BAPCR_01342 ENOG4105CGH 5'-nucleotidase BAPCR_01345 ENOG4105VZ8 Transcriptional regulator BAPCR_01348 ENOG4108VXD carboxy-peptidase BAPCR_01352 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BAPCR_01353 ENOG41067SE Tetr family transcriptional regulator BAPCR_01354 ENOG4105C5H ABC transporter BAPCR_01356 ENOG4105BZU Histidine kinase BAPCR_01358 ENOG4106ANW SMI1_KNR4 BAPCR_01361 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BAPCR_01364 ENOG4105CJ1 ABC, transporter BAPCR_01366 ENOG4107Z3H Transcriptional regulator, TetR family BAPCR_01369 ENOG4105C1G acyl-Coa dehydrogenase BAPCR_01370 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAPCR_01371 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAPCR_01372 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAPCR_01373 ENOG4105E39 Enoyl-CoA hydratase BAPCR_01374 ENOG4107QX3 carboxylase BAPCR_01375 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAPCR_01377 ENOG4105WCN acetyltransferase BAPCR_01378 ENOG4105DBI uridine monophosphokinase BAPCR_01381 ENOG4105DZ1 carboxypeptidase BAPCR_01384 ENOG4105T9C HD domain BAPCR_01386 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BAPCR_01396 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPCR_01396 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPCR_01399 ENOG4105FQP Beta-lactamase BAPCR_01401 ENOG4107Y80 Major Facilitator superfamily BAPCR_01404 ENOG4105CUV Homoserine Kinase BAPCR_01410 ENOG4105CPQ Dehydrogenase BAPCR_01413 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPCR_01414 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPCR_01435 ENOG4105ETU transcriptional activator (TenA BAPCR_01456 ENOG4106A3M Cytochrome p-450 BAPCR_01460 ENOG410667J hydrolase BAPCR_01462 ENOG4105BZU Histidine kinase BAPCR_01463 ENOG4107RF6 penicillin-binding protein BAPCR_01468 ENOG4108JJB ABC transporter BAPCR_01471 ENOG4108HGU Histidine kinase BAPCR_01475 ENOG4105CB2 alcohol dehydrogenase BAPCR_01476 ENOG4105CJN penicillin-binding protein BAPCR_01478 ENOG4105FQP Beta-lactamase BAPCR_01486 ENOG4108V4B ThiJ pfpI BAPCR_01491 ENOG4107Y80 Major Facilitator superfamily BAPCR_01495 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAPCR_01500 ENOG4107Y9U Membrane BAPCR_01507 ENOG4105FCD Major Facilitator BAPCR_01509 ENOG4105E09 nadh pyrophosphatase BAPCR_01510 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAPCR_01511 ENOG4108Z4K mutator MutT protein BAPCR_01518 ENOG4108XI2 Domain of unknown function (DUF1963) BAPCR_01524 ENOG4108NRW Phospholipase, patatin family BAPCR_01525 ENOG4105KWG Pfam:DUF1696 BAPCR_01532 ENOG4105PKS Excinuclease abc c subunit domain protein BAPCR_01540 ENOG4107VFR oxidoreductase BAPCR_01545 ENOG4105PAD Hydrolase BAPCR_01549 ENOG4105DY8 decarboxylase BAPCR_01553 ENOG4108IUM Glycogen debranching enzyme BAPCR_01558 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAPCR_01560 ENOG4105FDR Membrane BAPCR_01567 ENOG4108V3A UPF0421 protein BAPCR_01571 ENOG4105MSI germination protein ypeb BAPCR_01575 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BAPCR_01576 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BAPCR_01577 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BAPCR_01578 ENOG4107Z3H Transcriptional regulator, TetR family BAPCR_01584 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAPCR_01588 ENOG4105E98 transcriptional regulator DeoR family BAPCR_01592 ENOG41062ES Transcriptional regulator BAPCR_01597 ENOG4107QKR Dehydrogenase BAPCR_01599 ENOG4107RUY (E1 component), alpha subunit BAPCR_01601 ENOG4105E1F short-chain dehydrogenase reductase BAPCR_01602 ENOG4105RHY Pfam:UPF0157 BAPCR_01608 ENOG4107SQ8 Glycine betaine BAPCR_01609 ENOG4108IJ7 Glycine betaine BAPCR_01614 ENOG4105E66 phosphoriboisomerase A BAPCR_01615 ENOG41082BV acetyltransferase BAPCR_01616 ENOG4108M1A Chitin-binding protein BAPCR_01625 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAPCR_01631 ENOG4108Z7F N-acetyltransferase BAPCR_01635 ENOG4105EEM helicase BAPCR_01639 ENOG4105C9U ATP-dependent DNA helicase RecQ BAPCR_01648 ENOG4108M1A Chitin-binding protein BAPCR_01651 ENOG4105BZG amino acid carrier protein BAPCR_01652 ENOG4105C26 Dehydrogenase BAPCR_01653 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAPCR_01654 ENOG4105CTU Proline racemase BAPCR_01655 ENOG4105CTU Proline racemase BAPCR_01656 ENOG41080HI glycine oxidase BAPCR_01663 ENOG4107T5V SNARE associated Golgi BAPCR_01666 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAPCR_01667 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAPCR_01670 ENOG4105DTQ mandelate racemase muconate lactonizing BAPCR_01678 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BAPCR_01679 ENOG4105BZU Histidine kinase BAPCR_01680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_01687 ENOG4105DPN Oligoendopeptidase f BAPCR_01690 ENOG4105EPR degv family BAPCR_01698 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAPCR_01699 ENOG4106K7D Major facilitator family transporter BAPCR_01703 ENOG4107BMA Transglycosylase associated protein BAPCR_01706 ENOG41089UC methyltransferase, type 11 BAPCR_01713 ENOG4105CHM Aminotransferase BAPCR_01719 ENOG4105DVE abc transporter atp-binding protein BAPCR_01728 ENOG4105C02 permease BAPCR_01730 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BAPCR_01731 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAPCR_01732 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAPCR_01738 ENOG4105E09 nadh pyrophosphatase BAPCR_01742 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BAPCR_01754 ENOG4107VMI polysaccharide deacetylase BAPCR_01756 ENOG4108ZCF integral membrane protein BAPCR_01757 ENOG4105E0M Sulfatase BAPCR_01758 ENOG4105C5H ABC transporter BAPCR_01760 ENOG4105EYF MMPL domain protein BAPCR_01762 ENOG4105EYF MMPL domain protein BAPCR_01763 ENOG41082JN Transcriptional regulator BAPCR_01767 ENOG4105CIH Imidazole acetol-phosphate transaminase BAPCR_01768 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAPCR_01769 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAPCR_01777 ENOG41069ER domain protein BAPCR_01779 ENOG4105EMN RNA polymerase sigma factor BAPCR_01785 ENOG4105D4B ABC, transporter BAPCR_01787 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BAPCR_01789 ENOG4105DKT Transcriptional regulator BAPCR_01790 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BAPCR_01792 ENOG41061GT Aldolase BAPCR_01796 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAPCR_01802 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAPCR_01803 ENOG4105II7 pyrroline-5-carboxylate reductase BAPCR_01805 ENOG4107258 Transcriptional regulator BAPCR_01807 ENOG4105E0Y RtcB Protein BAPCR_01808 ENOG4105ECK Fatty Acid Desaturase BAPCR_01809 ENOG4105G6Z alkaline phosphatase BAPCR_01811 ENOG4105VMP Transcriptional regulator BAPCR_01814 ENOG41090T1 Membrane BAPCR_01816 ENOG4108WCX response regulator BAPCR_01818 ENOG41068WN BAPCR_01823 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPCR_01829 ENOG4105CKK Glycosyl transferase, family 2 BAPCR_01834 ENOG4105CKK Glycosyl transferase, family 2 BAPCR_01836 ENOG4105C8Y Acetylornithine aminotransferase BAPCR_01845 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPCR_01847 ENOG4108TVJ Nitroreductase BAPCR_01848 ENOG4105FS7 Transcriptional regulator BAPCR_01856 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPCR_01858 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BAPCR_01864 ENOG4108XET gCN5-related N-acetyltransferase BAPCR_01880 ENOG410635A Membrane BAPCR_01881 ENOG4105KNA -acetyltransferase BAPCR_01882 ENOG4108IQI permease BAPCR_01884 ENOG4105F1N DNA alkylation repair BAPCR_01892 ENOG4107RF6 penicillin-binding protein BAPCR_01894 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAPCR_01903 ENOG4105P4J Allophanate hydrolase, subunit 1 BAPCR_01904 ENOG4107258 Transcriptional regulator BAPCR_01906 ENOG4106N3A copper homeostasis protein cutc BAPCR_01907 ENOG4108ZRV stage ii sporulation protein p BAPCR_01908 ENOG4108ZHR arsR family transcriptional regulator BAPCR_01910 ENOG4105FDT acyl-CoA dehydrogenase BAPCR_01914 ENOG4105DWD nucleoside recognition domain protein BAPCR_01920 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAPCR_01935 ENOG4105E2A Dehydrogenase BAPCR_01938 ENOG4108IJ0 Aspartate ammonia-lyase BAPCR_01939 ENOG4105HDK L-asparaginase BAPCR_01940 ENOG4108IMY Transcriptional regulator BAPCR_01942 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAPCR_01943 ENOG4105CUB amino acid BAPCR_01945 ENOG4105II7 pyrroline-5-carboxylate reductase BAPCR_01947 ENOG4105C6K Malic enzyme BAPCR_01949 ENOG4108NHD germination protein BAPCR_01950 ENOG4108Q8B Spore germination protein BAPCR_01951 ENOG4108Q8B Spore germination protein BAPCR_01955 ENOG4105CSV Glutaminase BAPCR_01963 ENOG4105CGH 5'-nucleotidase BAPCR_01964 ENOG4105CH6 catalase BAPCR_01966 ENOG4105CHJ isochorismatase hydrolase BAPCR_01971 ENOG41090MY MarR family Transcriptional regulator BAPCR_01978 ENOG4108606 TspO/MBR family BAPCR_01979 ENOG4105CVP deoxyribo-dipyrimidine photolyase BAPCR_01982 ENOG4108TWJ NADH dehydrogenase subunit 5 BAPCR_01983 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BAPCR_01985 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAPCR_01986 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BAPCR_01987 ENOG4105DSE periplasmic solute binding protein BAPCR_01988 ENOG4105CC5 ABC transporter BAPCR_01989 ENOG4105DIK (ABC) transporter BAPCR_01995 ENOG4105D6J arsenicaL-resistance protein BAPCR_01996 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_01997 ENOG41085FC arsR family transcriptional regulator BAPCR_02001 ENOG4105F7F Chaperone BAPCR_02003 ENOG4105CHR reductase BAPCR_02004 ENOG4108YXU transcriptional regulator AsnC family BAPCR_02018 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAPCR_02019 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_02021 ENOG4105IIP Membrane BAPCR_02024 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_02025 ENOG41062D9 Histidine kinase BAPCR_02030 ENOG4105K6H D-cysteine desulfhydrase BAPCR_02036 ENOG4105VZ8 Transcriptional regulator BAPCR_02039 ENOG4108NNI Beta-lactamase domain-containing protein BAPCR_02040 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAPCR_02042 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPCR_02043 ENOG4105JQZ Methyltransferase BAPCR_02046 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAPCR_02047 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BAPCR_02050 ENOG4105BZU Histidine kinase BAPCR_02053 ENOG4108U05 Transcriptional regulator BAPCR_02054 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAPCR_02056 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAPCR_02057 ENOG4105DJB Major Facilitator Superfamily BAPCR_02058 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BAPCR_02059 ENOG4107QR9 Iron-sulfur cluster binding protein BAPCR_02061 ENOG4106P55 Transcriptional regulator BAPCR_02063 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAPCR_02069 ENOG4105TRI Hydrolase BAPCR_02077 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPCR_02084 ENOG4107QJQ Mate efflux family protein BAPCR_02087 ENOG4105MZU cell filamentation protein BAPCR_02088 ENOG4105EQ0 Major Facilitator superfamily BAPCR_02089 ENOG4108JGH Tetr family transcriptional regulator BAPCR_02092 ENOG4105C44 Serine transporter BAPCR_02093 ENOG4105EJQ L-serine dehydratase BAPCR_02095 ENOG4108JPW Aminotransferase BAPCR_02101 ENOG4105DVH amino acid BAPCR_02104 ENOG4108JQ1 Dehydrogenase BAPCR_02108 ENOG4108AEY RNA polymerase sigma factor BAPCR_02111 ENOG41082W1 Cupin 2, conserved barrel domain protein BAPCR_02112 ENOG410874W AraC family transcriptional regulator BAPCR_02115 ENOG4105HIR S-layer domain protein BAPCR_02123 ENOG4108ISG Major Facilitator BAPCR_02125 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAPCR_02126 ENOG4105CZM Major Facilitator BAPCR_02130 ENOG4105DA5 (ABC) transporter BAPCR_02131 ENOG41069JR BAPCR_02133 ENOG4105RXJ BAPCR_02134 ENOG4105KPY Small multidrug resistance protein BAPCR_02135 ENOG4105KBX Transcriptional regulator, TetR family BAPCR_02137 ENOG4105CRW Short chain fatty acid transporter BAPCR_02139 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAPCR_02146 ENOG4108JJB ABC transporter BAPCR_02147 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAPCR_02152 ENOG4108K8S endonuclease I BAPCR_02155 ENOG41067QW Transcriptional regulator BAPCR_02157 ENOG4108Z66 YbaK ebsC protein BAPCR_02158 ENOG4105CUT histidyl-tRNA synthetase BAPCR_02161 ENOG4105KVH Transcriptional regulator BAPCR_02162 ENOG4108RCM Nitroreductase BAPCR_02166 ENOG4108PSK reductase BAPCR_02168 ENOG4105CJ1 ABC, transporter BAPCR_02180 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_02181 ENOG4105DKQ ROK family BAPCR_02182 ENOG4106UW1 Major Facilitator superfamily BAPCR_02183 ENOG4108UW5 maltose o-acetyltransferase BAPCR_02185 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAPCR_02187 ENOG4105C31 Tryptophanyl-tRNA synthetase BAPCR_02188 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAPCR_02193 ENOG4105DMQ Methyltransferase BAPCR_02195 ENOG4105EV4 Multidrug resistance protein mdtH BAPCR_02202 ENOG4105C37 (CBS) domain BAPCR_02205 ENOG4105DDN Pentapeptide repeat-containing protein BAPCR_02206 ENOG4105XDF Protein of unknown function (DUF1272) BAPCR_02207 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAPCR_02208 ENOG4105CMG Carbohydrate kinase BAPCR_02209 ENOG4105C6Z Gluconate BAPCR_02210 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAPCR_02213 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAPCR_02214 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAPCR_02215 ENOG4105CIS alcohol dehydrogenase BAPCR_02216 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BAPCR_02219 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAPCR_02220 ENOG4105D4Y metalloprotease BAPCR_02224 ENOG4105CV8 reductase BAPCR_02225 ENOG4105F27 Major Facilitator BAPCR_02228 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAPCR_02229 ENOG4105C44 Serine transporter BAPCR_02235 ENOG4105KVH Transcriptional regulator BAPCR_02236 ENOG4108TZY GntR Family Transcriptional Regulator BAPCR_02237 ENOG4105D9R oxidoreductase BAPCR_02238 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BAPCR_02239 ENOG4105KVH Transcriptional regulator BAPCR_02240 ENOG4105KVH Transcriptional regulator BAPCR_02247 ENOG4105JAB phenazine biosynthesis protein, phzf family BAPCR_02249 ENOG4105CHR reductase BAPCR_02253 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAPCR_02254 ENOG4105KVH Transcriptional regulator BAPCR_02258 ENOG4105CKK Glycosyl transferase, family 2 BAPCR_02259 ENOG4108ZJ4 polysaccharide deacetylase BAPCR_02269 ENOG4105KAF membrAne BAPCR_02274 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BAPCR_02279 ENOG4107YXZ hydrolase, family 25 BAPCR_02284 ENOG4105ED2 Beta-lactamase BAPCR_02286 ENOG4105H3G oxidoreductase BAPCR_02293 ENOG4105CIS alcohol dehydrogenase BAPCR_02300 ENOG4108TN2 lmbE family BAPCR_02302 ENOG4107R3E Citrate transporter BAPCR_02306 ENOG4108MES Periplasmic binding protein BAPCR_02308 ENOG4105EHG Permease protein BAPCR_02309 ENOG4105DQ5 transport system permease protein BAPCR_02310 ENOG4105NX3 Membrane BAPCR_02311 ENOG4107ZY0 Phenazine biosynthesis-like protein BAPCR_02315 ENOG4107CUJ Protein of unknown function (DUF2690) BAPCR_02317 ENOG4107V2S Transcriptional regulator BAPCR_02321 ENOG4105C98 muts2 protein BAPCR_02323 ENOG4105E5K Alpha-amylase BAPCR_02325 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAPCR_02326 ENOG4105DPN Oligoendopeptidase f BAPCR_02327 ENOG4108A04 Beta-lactamase BAPCR_02333 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAPCR_02337 ENOG41082BM Transcriptional regulator, arsr family BAPCR_02338 ENOG4105CIS alcohol dehydrogenase BAPCR_02345 ENOG4105RHY Pfam:UPF0157 BAPCR_02347 ENOG4105C09 Bile acid BAPCR_02348 ENOG4105CQB FAD linked oxidase domain protein BAPCR_02352 ENOG4108UT6 Transferase hexapeptide repeat containing protein BAPCR_02354 ENOG4105K64 Glycosyl transferase, family 2 BAPCR_02355 ENOG4105E39 Enoyl-CoA hydratase BAPCR_02357 ENOG4105KT7 mgtC SapB transporter BAPCR_02359 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_02360 ENOG41073R8 VanW family BAPCR_02362 ENOG4108R1P BAPCR_02366 ENOG4105VEQ Cold shock protein BAPCR_02370 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BAPCR_02374 ENOG410904N short-chain dehydrogenase reductase BAPCR_02376 ENOG4106IQC argininosuccinate lyase BAPCR_02380 ENOG4108IA2 Sodium pantothenate symporter BAPCR_02382 ENOG4105C26 Dehydrogenase BAPCR_02383 ENOG4105CHR reductase BAPCR_02385 ENOG4105EWU Squalene--hopene cyclase BAPCR_02387 ENOG4105FR1 rard protein BAPCR_02388 ENOG410696E Membrane BAPCR_02391 ENOG4105D1F ATP-binding protein BAPCR_02393 ENOG4108ZAF Molybdopterin BAPCR_02394 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPCR_02395 ENOG4105D06 uba thif-type nad fad binding protein BAPCR_02396 ENOG4105TMB Formate nitrite transporter BAPCR_02398 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAPCR_02399 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAPCR_02401 ENOG4108JB9 formate dehydrogenase BAPCR_02402 ENOG4108JB9 formate dehydrogenase BAPCR_02404 ENOG4105E1K spore germination protein BAPCR_02415 ENOG4107QJT sodium dicarboxylate symporter BAPCR_02416 ENOG4108KGH TRANSCRIPTIONal BAPCR_02418 ENOG4105EMN RNA polymerase sigma factor BAPCR_02422 ENOG4105CIG ABC transporter BAPCR_02424 ENOG4105D9R oxidoreductase BAPCR_02426 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAPCR_02427 ENOG4105K4P CoA-binding domain protein BAPCR_02428 ENOG4105C0H protease BAPCR_02429 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_02431 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BAPCR_02432 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAPCR_02433 ENOG4105W8X HesB YadR YfhF-family protein BAPCR_02439 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAPCR_02440 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAPCR_02442 ENOG4108JJA ABC, transporter BAPCR_02443 ENOG4108I0Z Aconitate hydratase BAPCR_02448 ENOG4105E5W Transporter BAPCR_02450 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPCR_02454 ENOG4107F3J Amp-dependent synthetase and ligase BAPCR_02455 ENOG4107ZYJ bioY protein BAPCR_02456 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_02465 ENOG4107AYK membrAne BAPCR_02467 ENOG4105BZU Histidine kinase BAPCR_02468 ENOG4105FBA Phospholipase Carboxylesterase BAPCR_02469 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAPCR_02470 ENOG4105CK7 Sodium proline symporter BAPCR_02471 ENOG4105CBC glutamate synthase BAPCR_02472 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAPCR_02473 ENOG4108VJ1 Transcriptional regulator (CarD family BAPCR_02474 ENOG4108903 Formimidoylglutamase BAPCR_02479 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BAPCR_02490 ENOG4107QIV Cytochrome c biogenesis protein BAPCR_02492 ENOG4107RSM transcriptional regulator BAPCR_02493 ENOG4105VAW lrga family BAPCR_02494 ENOG41067MG lrgb family BAPCR_02500 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPCR_02503 ENOG4105BZ1 (ABC) transporter BAPCR_02504 ENOG4105BZ1 (ABC) transporter BAPCR_02508 ENOG4105D7V transposase BAPCR_02511 ENOG4105D5T phosphonate abc transporter BAPCR_02514 ENOG4105CGH 5'-nucleotidase BAPCR_02516 ENOG4108SVB resolvase BAPCR_02520 ENOG4105K7K Transcriptional regulator BAPCR_02528 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAPCR_02529 ENOG4105XSJ toxin secretion phage lysis holin BAPCR_02568 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BAPCR_02589 ENOG4105C5F glutamine synthetase BAPCR_02590 ENOG4105KV4 Transcriptional regulator BAPCR_02591 ENOG4105CXI aluminum resistance protein BAPCR_02592 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAPCR_02593 ENOG4105EN6 Membrane BAPCR_02595 ENOG4106F1P AAA ATPase, central domain protein BAPCR_02601 ENOG41069ER domain protein BAPCR_02602 ENOG4105DM4 PTS System BAPCR_02603 ENOG4105DE4 1-phosphofructokinase BAPCR_02604 ENOG4105E98 transcriptional regulator DeoR family BAPCR_02605 ENOG4107QW4 alcohol dehydrogenase BAPCR_02606 ENOG4107QW4 alcohol dehydrogenase BAPCR_02607 ENOG4108SJC Membrane BAPCR_02610 ENOG4105C85 amino acid BAPCR_02614 ENOG4105TMB Formate nitrite transporter BAPCR_02615 ENOG4105K70 DNA-binding protein BAPCR_02616 ENOG4105C59 p-type ATPase BAPCR_02617 ENOG410681U heavy metal transport detoxification protein BAPCR_02618 ENOG4105VPX protein, conserved in bacteria BAPCR_02620 ENOG4105NIV Esterase BAPCR_02621 ENOG4105E0A ABC, transporter BAPCR_02626 ENOG4105CGK Exodeoxyribonuclease III BAPCR_02627 ENOG4105CGK Exodeoxyribonuclease III BAPCR_02629 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAPCR_02630 ENOG4105D03 DNA-3-methyladenine glycosylase II BAPCR_02636 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_02637 ENOG4105BZU Histidine kinase BAPCR_02638 ENOG4105BZU Histidine kinase BAPCR_02641 ENOG41067MG lrgb family BAPCR_02644 ENOG4107TTQ Alpha beta hydrolase fold BAPCR_02645 ENOG4107YEI lmbE family BAPCR_02649 ENOG4105F0V Cell wall hydrolase BAPCR_02650 ENOG4107R6R udp-galactopyranose mutase BAPCR_02651 ENOG4105E0M Sulfatase BAPCR_02652 ENOG410890F Dynamin family BAPCR_02654 ENOG4107QHE Choloylglycine hydrolase BAPCR_02659 ENOG4105DA5 (ABC) transporter BAPCR_02664 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAPCR_02665 ENOG4105DQU oxidoreductase, subunit beta BAPCR_02666 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BAPCR_02667 ENOG4108IGT Dipeptidase BAPCR_02668 ENOG4105MCT stage V sporulation protein S BAPCR_02669 ENOG4105D48 metallophosphoesterase BAPCR_02674 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAPCR_02677 ENOG4105XZV Protein of unknown function (DUF3243) BAPCR_02678 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAPCR_02682 ENOG4105UIB (ABC) transporter BAPCR_02683 ENOG4105UIB (ABC) transporter BAPCR_02684 ENOG4108JQ9 ABC transporter BAPCR_02685 ENOG4105DIH basic membrane BAPCR_02686 ENOG4105FDP GntR family transcriptional regulator BAPCR_02687 ENOG4107QZI cell division protein FtsK BAPCR_02689 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAPCR_02691 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAPCR_02693 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAPCR_02694 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAPCR_02695 ENOG4105E35 Dipicolinate synthase subunit A BAPCR_02697 ENOG4105C1V Peptidase, M16 BAPCR_02701 ENOG4105DTN riboflavin biosynthesis protein ribF BAPCR_02702 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAPCR_02704 ENOG4105W7A Protein of unknown function (DUF503) BAPCR_02706 ENOG4105VHM ribosomal protein BAPCR_02707 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAPCR_02708 ENOG4105CHV Transcription elongation factor NusA BAPCR_02710 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAPCR_02712 ENOG4105DZP Membrane-associated zinc metalloprotease BAPCR_02713 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAPCR_02714 ENOG4105KNE Phosphatidate cytidylyltransferase BAPCR_02723 ENOG4108HE4 integrase family BAPCR_02725 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPCR_02728 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAPCR_02731 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAPCR_02736 ENOG4105VB6 UPF0109 protein BAPCR_02740 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAPCR_02741 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAPCR_02744 ENOG4105CHR reductase BAPCR_02745 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAPCR_02748 ENOG4105CB5 ATP-dependent DNA helicase recG BAPCR_02749 ENOG4105DP4 dak2 domain fusion protein ylov BAPCR_02750 ENOG4108ZAA Alkaline-shock protein BAPCR_02752 ENOG4105FJ0 thiamine BAPCR_02753 ENOG4105DJV ribulose-phosphate 3-epimerase BAPCR_02754 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAPCR_02755 ENOG4105D9P serine threonine protein kinase BAPCR_02756 ENOG4108ZF3 Phosphatase BAPCR_02758 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAPCR_02760 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAPCR_02761 ENOG4105C25 Primosomal protein n' BAPCR_02762 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAPCR_02766 ENOG4105DSJ YicC domain protein BAPCR_02769 ENOG4105F23 Fibronectin-binding protein BAPCR_02770 ENOG4105DC7 peptidase M24 BAPCR_02782 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAPCR_02787 ENOG4105C34 Pseudouridine synthase BAPCR_02790 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAPCR_02792 ENOG4105DBK s4 domain protein BAPCR_02793 ENOG41067XK integral membrane protein BAPCR_02795 ENOG4105DFA alanine racemase domain protein BAPCR_02796 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAPCR_02797 ENOG4105WR5 sporulation protein, YlmC YmxH family BAPCR_02799 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_02801 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAPCR_02802 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAPCR_02803 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAPCR_02804 ENOG4105D4A Cell wall formation (By similarity) BAPCR_02805 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAPCR_02806 ENOG4105CNI cell division protein FtsW BAPCR_02809 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPCR_02810 ENOG4105CJN penicillin-binding protein BAPCR_02811 ENOG4105CJN penicillin-binding protein BAPCR_02812 ENOG41068DC Essential cell division protein (By similarity) BAPCR_02819 ENOG4105KNH Nucleic acid-binding protein BAPCR_02829 ENOG4105XSJ toxin secretion phage lysis holin BAPCR_02848 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAPCR_02868 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAPCR_02882 ENOG4108IMY Transcriptional regulator BAPCR_02890 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAPCR_02892 ENOG41063PX domain protein BAPCR_02893 ENOG4105D78 K07001 NTE family protein BAPCR_02894 ENOG4105H20 Sporulation integral membrane protein YlbJ BAPCR_02896 ENOG4106H78 methyltransferase BAPCR_02901 ENOG4107TB6 phosphoglycerate mutase BAPCR_02904 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAPCR_02914 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAPCR_02915 ENOG4105CNI cell division protein FtsW BAPCR_02916 ENOG4105CNI cell division protein FtsW BAPCR_02919 ENOG4108IAB Phoh family BAPCR_02923 ENOG4105QA2 BAPCR_02924 ENOG4105CI3 gtp-binding protein typa BAPCR_02926 ENOG4105ECY inositol monophosphatase BAPCR_02930 ENOG4105CXN decarboxylase BAPCR_02940 ENOG4105CPP Dehydrogenase, E1 component BAPCR_02943 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAPCR_02944 ENOG4108X4Q Hydrolase BAPCR_02946 ENOG4105CN5 Metallo-Beta-Lactamase BAPCR_02947 ENOG4107ZYR domain protein BAPCR_02954 ENOG4108XRC Protein of unknown function (DUF458) BAPCR_02956 ENOG4107IN1 Protein of unknown function (DUF1797) BAPCR_02959 ENOG4105EPM Diguanylate phosphodiesterase BAPCR_02960 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAPCR_02963 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BAPCR_02964 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BAPCR_02966 ENOG4105UIN BAPCR_02977 ENOG4108HGU Histidine kinase BAPCR_02979 ENOG4105CHM Aminotransferase BAPCR_02980 ENOG4105FKQ transcriptional regulator BAPCR_02981 ENOG4105EG2 ABC transporter, permease BAPCR_02983 ENOG4107FKK extracellular solute-binding protein family 1 BAPCR_02985 ENOG4105CG3 alpha amylase, catalytic region BAPCR_02994 ENOG4105CHU acetyl-coa acetyltransferase BAPCR_03001 ENOG4105K7K Transcriptional regulator BAPCR_03002 ENOG4105DTD Dehydrogenase BAPCR_03004 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAPCR_03006 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAPCR_03011 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAPCR_03014 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPCR_03015 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPCR_03016 ENOG4106TD9 Diguanylate cyclase BAPCR_03020 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAPCR_03023 ENOG4105CID antiterminator BAPCR_03025 ENOG4105FDP GntR family transcriptional regulator BAPCR_03027 ENOG4105CE4 GlcNAc 6-P deacetylase BAPCR_03034 ENOG4107ZE5 PPIases accelerate the folding of proteins BAPCR_03035 ENOG4105PTM secreted protein BAPCR_03036 ENOG4105J7I hydrolase BAPCR_03038 ENOG4105G6R Stage v sporulation protein ae BAPCR_03040 ENOG4105CZ3 stage V sporulation protein ad BAPCR_03041 ENOG41090VF Stage v sporulation protein ac BAPCR_03045 ENOG4105C8J )-transporter BAPCR_03046 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_03048 ENOG41082AN stage II sporulation protein BAPCR_03049 ENOG4105DZ1 carboxypeptidase BAPCR_03050 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPCR_03051 ENOG4105DVE abc transporter atp-binding protein BAPCR_03057 ENOG4105D7N magnesium and cobalt transport protein CorA BAPCR_03062 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPCR_03064 ENOG4105I3K Ferric uptake regulator, Fur family BAPCR_03065 ENOG4105MZ9 stage II sporulation protein m BAPCR_03069 ENOG4105CPC Aldo Keto reductase BAPCR_03071 ENOG4105RHY Pfam:UPF0157 BAPCR_03075 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAPCR_03077 ENOG4105ETE Transcriptional regulator (LacI family BAPCR_03078 ENOG4108YM7 Gcn5-related n-acetyltransferase BAPCR_03082 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAPCR_03083 ENOG4108R6K riboflavin synthase, subunit alpha BAPCR_03087 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAPCR_03088 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAPCR_03089 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAPCR_03090 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAPCR_03092 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPCR_03094 ENOG4105DFD Na H antiporter BAPCR_03095 ENOG4105CGH 5'-nucleotidase BAPCR_03103 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BAPCR_03106 ENOG4108IXY short-chain dehydrogenase reductase BAPCR_03107 ENOG41069FQ Metallo-beta-lactamase superfamily BAPCR_03108 ENOG4105II7 pyrroline-5-carboxylate reductase BAPCR_03109 ENOG4105EJQ L-serine dehydratase BAPCR_03113 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPCR_03115 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAPCR_03116 ENOG4105D9U N-acetyltransferase BAPCR_03118 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAPCR_03119 ENOG4108QEG Membrane BAPCR_03120 ENOG4105CDA abc transporter atp-binding protein BAPCR_03121 ENOG4105E5Q amino acid AbC transporter BAPCR_03122 ENOG4108HW3 (ABC) transporter BAPCR_03124 ENOG4105G7B Protein of unknown function (DUF2992) BAPCR_03125 ENOG4105E09 nadh pyrophosphatase BAPCR_03127 ENOG4105C7S Dehydrogenase BAPCR_03128 ENOG4105CPP Dehydrogenase, E1 component BAPCR_03132 ENOG4107RDP Dehydrogenase BAPCR_03134 ENOG4108JUB Transcriptional regulator BAPCR_03136 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAPCR_03139 ENOG4107QQR Sporulation BAPCR_03140 ENOG4105S1Z Stage IV sporulation protein B BAPCR_03141 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAPCR_03143 ENOG4105DX0 Hemolysin A BAPCR_03145 ENOG4105CTB Polyprenyl synthetase BAPCR_03150 ENOG4108ZSR alkaline shock protein BAPCR_03151 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAPCR_03156 ENOG410644B Stage III sporulation protein af BAPCR_03158 ENOG4105KQ4 Stage iii sporulation protein ad BAPCR_03159 ENOG4108CQH stage III sporulation protein AC BAPCR_03160 ENOG4105KR5 Stage iii sporulation protein BAPCR_03161 ENOG4105CD2 stage iii sporulation protein aa BAPCR_03166 ENOG4105DC7 peptidase M24 BAPCR_03169 ENOG4105CBJ Metal-dependent enzyme BAPCR_03171 ENOG4107YBY Hydrolase BAPCR_03175 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAPCR_03176 ENOG4105WZW rhodanese family BAPCR_03180 ENOG41080TC multidrug resistance protein BAPCR_03187 ENOG4105CJ1 ABC, transporter BAPCR_03188 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPCR_03194 ENOG4105C0D helicase BAPCR_03206 ENOG4106855 Competence protein BAPCR_03218 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAPCR_03219 ENOG4105C3R Methionine synthase BAPCR_03222 ENOG4105C28 cystathionine BAPCR_03223 ENOG4105C28 cystathionine BAPCR_03227 ENOG4105C5X domain protein BAPCR_03229 ENOG4105DKQ ROK family BAPCR_03231 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAPCR_03234 ENOG4108UTW Plays a role in the regulation of phosphate uptake BAPCR_03235 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAPCR_03236 ENOG4105E2Z phosphate ABC transporter (Permease BAPCR_03237 ENOG4105C8U phosphate abc transporter BAPCR_03238 ENOG4105PWN phosphate abc transporter BAPCR_03239 ENOG4107RF6 penicillin-binding protein BAPCR_03241 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPCR_03246 ENOG4105N80 Ferric uptake regulator, Fur family BAPCR_03248 ENOG4105FDK ABC transporter BAPCR_03249 ENOG4108JYZ YitT family BAPCR_03250 ENOG41069ZM Protein of unknown function (DUF2624) BAPCR_03255 ENOG4105EGD dinuclear metal center protein, YbgI family BAPCR_03258 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_03259 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAPCR_03264 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAPCR_03265 ENOG4105KG3 cytidine deaminase BAPCR_03266 ENOG4107YR5 Diacylglycerol kinase BAPCR_03268 ENOG4105CTJ Metal Dependent Phosphohydrolase BAPCR_03269 ENOG4105C9A Phoh family BAPCR_03271 ENOG41068P3 sporulation protein YqfC BAPCR_03272 ENOG4105KTH gatB Yqey BAPCR_03274 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAPCR_03275 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAPCR_03279 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAPCR_03281 ENOG4105CSA Coproporphyrinogen iii oxidase BAPCR_03282 ENOG4105KVH Transcriptional regulator BAPCR_03287 ENOG4105TQK DNA polymerase iii, delta' subunit BAPCR_03289 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAPCR_03290 ENOG4108UK2 deaminase BAPCR_03291 ENOG4105KQC Competence protein BAPCR_03293 ENOG4105DXX methyltransferase BAPCR_03295 ENOG4108WF2 Metal Dependent Phosphohydrolase BAPCR_03297 ENOG410812S Rna-binding protein BAPCR_03299 ENOG4105CQW ribosome biogenesis GTPase YqeH BAPCR_03300 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAPCR_03303 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_03307 ENOG4108TVJ Nitroreductase BAPCR_03310 ENOG4105G6Z alkaline phosphatase BAPCR_03312 ENOG4108MUZ hydrolase BAPCR_03319 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAPCR_03320 ENOG4105MIR Phenylalanine 4-monooxygenase BAPCR_03322 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_03330 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAPCR_03331 ENOG4108V5C ABC transporter BAPCR_03333 ENOG4108EKI Dehydrogenase BAPCR_03334 ENOG4105C28 cystathionine BAPCR_03340 ENOG4107XRG penicillin-binding protein BAPCR_03343 ENOG4105CFP Peptidase U32 BAPCR_03344 ENOG4105XYU peptidase (U32 family) BAPCR_03345 ENOG4108VQJ O-methyltransferase BAPCR_03346 ENOG4105HHA aminodeoxychorismate lyase BAPCR_03350 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPCR_03352 ENOG4105C02 permease BAPCR_03355 ENOG41060CR BAPCR_03356 ENOG4105C7H Helicase, RecD TraA family BAPCR_03358 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAPCR_03359 ENOG4105C3J Cysteine desulfurase BAPCR_03361 ENOG4105D1H recombination factor protein RarA BAPCR_03362 ENOG4108VCI transcription factor, rsfa family BAPCR_03363 ENOG4105CUZ uba thif-type nad fad binding protein BAPCR_03365 ENOG4105CUT histidyl-tRNA synthetase BAPCR_03368 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAPCR_03370 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAPCR_03371 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAPCR_03372 ENOG41076HS cation diffusion facilitator family transporter BAPCR_03373 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAPCR_03375 ENOG4105CKP Polysaccharide Biosynthesis Protein BAPCR_03376 ENOG4108QG2 Membrane BAPCR_03378 ENOG4105VIE preprotein translocase, subunit YajC BAPCR_03381 ENOG41061AI Protein of unknown function (DUF2905) BAPCR_03384 ENOG4108HUF Transporter BAPCR_03386 ENOG4108IPJ Membrane BAPCR_03387 ENOG4108IPJ Membrane BAPCR_03388 ENOG41082BM Transcriptional regulator, arsr family BAPCR_03393 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAPCR_03394 ENOG4108IYU L-aspartate oxidase BAPCR_03397 ENOG4108RPX mosc domain containing protein BAPCR_03398 ENOG4105CQC Prephenate dehydratase BAPCR_03402 ENOG4105EWM Histidine kinase BAPCR_03405 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAPCR_03408 ENOG4105X36 (ribosomal) protein BAPCR_03410 ENOG4105C03 ribonuclease BAPCR_03413 ENOG4107QMS site-determining protein BAPCR_03416 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAPCR_03417 ENOG4105DFF Rod shape-determining protein mreb BAPCR_03421 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAPCR_03422 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAPCR_03424 ENOG41068KH stage VI sporulation protein D BAPCR_03426 ENOG4105D52 delta-aminolevulinic acid dehydratase BAPCR_03431 ENOG4105K56 Transcriptional regulator BAPCR_03435 ENOG4108IUQ atp-dependent protease BAPCR_03441 ENOG4108QCI YvbH-like oligomerisation region BAPCR_03445 ENOG4105M59 Phosphodiesterase, mj0936 family BAPCR_03446 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAPCR_03448 ENOG4108XJQ germination protein BAPCR_03450 ENOG4108PCX Major Facilitator BAPCR_03452 ENOG4105KBX Transcriptional regulator, TetR family BAPCR_03455 ENOG4105PFC Transcriptional regulator BAPCR_03458 ENOG4105DZC cytosine deaminase BAPCR_03459 ENOG4105DZC cytosine deaminase BAPCR_03460 ENOG4105DEF Extracellular solute-binding protein, family 5 BAPCR_03461 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPCR_03464 ENOG4108JQ7 (ABC) transporter BAPCR_03465 ENOG4108HRK Histidine kinase BAPCR_03466 ENOG4105DY9 regulatoR BAPCR_03469 ENOG41067S9 phage shock protein C, PspC BAPCR_03470 ENOG4108JCI Transcriptional regulator BAPCR_03472 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BAPCR_03473 ENOG4108Z40 Transcriptional regulator BAPCR_03474 ENOG4105RHA ABC transporter, permease BAPCR_03475 ENOG4108IUX (ABC) transporter BAPCR_03476 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BAPCR_03477 ENOG4105ER2 Ompa motb domain protein BAPCR_03478 ENOG4105ER2 Ompa motb domain protein BAPCR_03479 ENOG4105E14 MotA TolQ exbB proton channel BAPCR_03480 ENOG4108VXD carboxy-peptidase BAPCR_03482 ENOG4105E33 succinate dehydrogenase BAPCR_03484 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAPCR_03487 ENOG4105K63 Thioredoxin BAPCR_03488 ENOG4105C10 Electron transfer flavoprotein BAPCR_03489 ENOG4105BZJ Electron transfer flavoprotein BAPCR_03490 ENOG41060WC Enoyl-CoA hydratase BAPCR_03491 ENOG4107Z3H Transcriptional regulator, TetR family BAPCR_03492 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_03494 ENOG4105J76 Periplasmic binding protein BAPCR_03495 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAPCR_03504 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_03507 ENOG4105DR4 Methyltransferase BAPCR_03510 ENOG4105KFN sortase, SrtB family BAPCR_03511 ENOG4105E0A ABC, transporter BAPCR_03514 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BAPCR_03516 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BAPCR_03518 ENOG4105FE9 pseudouridine synthase BAPCR_03521 ENOG4105DCG PHP domain protein BAPCR_03528 ENOG4105C5S asparaginyl-tRNA synthetase BAPCR_03529 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAPCR_03531 ENOG4108RWN rrna methyltransferase BAPCR_03538 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_03539 ENOG4105CW7 secretion protein, HlyD family BAPCR_03540 ENOG4108JGH Tetr family transcriptional regulator BAPCR_03541 ENOG4105CN9 Peptidase m42 family protein BAPCR_03545 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAPCR_03546 ENOG4105C22 threonyL-tRNA synthetase BAPCR_03547 ENOG4108TDW sporulation protein YtxC BAPCR_03551 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAPCR_03552 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAPCR_03553 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAPCR_03555 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAPCR_03556 ENOG4105C2M dna polymerase I BAPCR_03557 ENOG4105BZU Histidine kinase BAPCR_03558 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_03562 ENOG4108HMX isocitrate dehydrogenase (NADP) BAPCR_03563 ENOG4105BZN citrate synthase BAPCR_03565 ENOG4108REF Sporulation integral membrane protein ytvi BAPCR_03566 ENOG4105FS0 cytoplasmic membrane protein BAPCR_03571 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAPCR_03572 ENOG4105C6K Malic enzyme BAPCR_03573 ENOG4105C0B DNA polymerase III (alpha subunit) BAPCR_03574 ENOG4105VV2 BAPCR_03576 ENOG4105SFS phosphoesterase RecJ domain protein BAPCR_03583 ENOG4105DC7 peptidase M24 BAPCR_03590 ENOG4105Z7P Acetyltransferase (GNAT) family BAPCR_03591 ENOG41082W1 Cupin 2, conserved barrel domain protein BAPCR_03593 ENOG4105VZ8 Transcriptional regulator BAPCR_03597 ENOG4107YZX Universal stress protein BAPCR_03605 ENOG4108JYZ YitT family BAPCR_03609 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAPCR_03611 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAPCR_03612 ENOG4105KBJ sporulation protein ytfj BAPCR_03615 ENOG4105EFZ amidohydrolase BAPCR_03617 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAPCR_03622 ENOG4106KR7 LysR family Transcriptional regulator BAPCR_03624 ENOG4105U5Y Transcriptional regulator BAPCR_03625 ENOG4105U5Y Transcriptional regulator BAPCR_03627 ENOG4105C28 cystathionine BAPCR_03631 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAPCR_03633 ENOG4105EMN RNA polymerase sigma factor BAPCR_03636 ENOG4105F1V Acetoin utilization protein BAPCR_03637 ENOG4105W87 Cbs domain BAPCR_03638 ENOG4105DGU Histone deacetylase BAPCR_03640 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_03642 ENOG4107SNB ankyrin repeat protein YahD BAPCR_03643 ENOG4105EP9 oxidoreductase BAPCR_03649 ENOG4105ETE Transcriptional regulator (LacI family BAPCR_03653 ENOG4105C88 aminopeptidase BAPCR_03663 ENOG4108VDD TRNA binding domain protein BAPCR_03669 ENOG4105C8F Beta-lactamase domain protein BAPCR_03672 ENOG4108V15 phosphotransferase enzyme family BAPCR_03673 ENOG4108IUM Glycogen debranching enzyme BAPCR_03675 ENOG4107QSE Dipeptidase BAPCR_03676 ENOG4105YW5 deoR family transcriptional regulator BAPCR_03679 ENOG4105CBX hi0933 family BAPCR_03686 ENOG4108VJ1 Transcriptional regulator (CarD family BAPCR_03687 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BAPCR_03688 ENOG4105CSC Glucose uptake protein BAPCR_03691 ENOG4108ZAF Molybdopterin BAPCR_03692 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAPCR_03693 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPCR_03694 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPCR_03696 ENOG4105D06 uba thif-type nad fad binding protein BAPCR_03697 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAPCR_03701 ENOG41085GJ domain protein BAPCR_03703 ENOG4105DWV Homoserine O-trans-acetylase BAPCR_03705 ENOG4108B31 Spore germination protein BAPCR_03711 ENOG410605W Major Facilitator BAPCR_03712 ENOG4107S91 Sodium hydrogen exchanger BAPCR_03713 ENOG4105NCW Trka-c domain protein BAPCR_03716 ENOG4105C19 ABC transporter BAPCR_03720 ENOG4105N5T Radical SAM Protein BAPCR_03722 ENOG4105DA5 (ABC) transporter BAPCR_03728 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAPCR_03729 ENOG4108Z0R Transferase BAPCR_03730 ENOG4105YVM Phosphoesterase, PA-phosphatase related BAPCR_03731 ENOG4105BZF Glycosyl transferase (Group 1 BAPCR_03733 ENOG4108RIR Molybdenum cofactor biosynthesis protein BAPCR_03743 ENOG4105EGD dinuclear metal center protein, YbgI family BAPCR_03744 ENOG4105BZU Histidine kinase BAPCR_03745 ENOG4105BZU Histidine kinase BAPCR_03746 ENOG4107S9D Alpha beta hydrolase BAPCR_03747 ENOG4107T7U Sulfatase BAPCR_03750 ENOG4105D2X ABC transporter substrate-binding protein BAPCR_03752 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAPCR_03756 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAPCR_03764 ENOG4108V2W Carbonate dehydratase BAPCR_03765 ENOG4105C4M (Ubiquinol oxidase) subunit I BAPCR_03766 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAPCR_03775 ENOG41087YS Phage shock protein A BAPCR_03782 ENOG4105BZU Histidine kinase BAPCR_03783 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_03788 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAPCR_03789 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAPCR_03796 ENOG4107ZTW SNARE associated Golgi BAPCR_03799 ENOG4105C19 ABC transporter BAPCR_03800 ENOG41086D8 Transcriptional regulator BAPCR_03809 ENOG4105C6Z Gluconate BAPCR_03810 ENOG4105FDP GntR family transcriptional regulator BAPCR_03814 ENOG41069H0 dihydroorotase EC 3.5.2.3 BAPCR_03820 ENOG4105DTQ mandelate racemase muconate lactonizing BAPCR_03822 ENOG4108IPT Naphthoate synthase BAPCR_03823 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAPCR_03824 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAPCR_03825 ENOG4105E4F Isochorismate synthase BAPCR_03826 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAPCR_03828 ENOG4105VEQ Cold shock protein BAPCR_03833 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BAPCR_03835 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BAPCR_03837 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPCR_03856 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BAPCR_03863 ENOG4105KT7 mgtC SapB transporter BAPCR_03864 ENOG4107PBV potassium channel BAPCR_03866 ENOG4107QYV phosphohexose isomerase BAPCR_03867 ENOG4105WG9 Conserved Protein BAPCR_03869 ENOG4105CHM Aminotransferase BAPCR_03870 ENOG4108ZB6 transcriptional regulator AsnC family BAPCR_03871 ENOG4105C5I Dehydrogenase BAPCR_03872 ENOG4108MUZ hydrolase BAPCR_03874 ENOG4105C87 Aminotransferase class I and II BAPCR_03877 ENOG4105Y38 Kinase-associated protein B BAPCR_03879 ENOG4107R3E Citrate transporter BAPCR_03882 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BAPCR_03883 ENOG4105KA0 thioesterase Superfamily protein BAPCR_03887 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAPCR_03891 ENOG41069ER domain protein BAPCR_03894 ENOG4105CEP NADH dehydrogenase BAPCR_03900 ENOG4105EWC Purine nucleoside phosphorylase BAPCR_03903 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAPCR_03907 ENOG4108JJA ABC, transporter BAPCR_03908 ENOG4105C4B ABC transporter, permease BAPCR_03909 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BAPCR_03918 ENOG41083MR nifu domain-containing protein BAPCR_03921 ENOG4108W5N phosphatidylglycerophosphatase a BAPCR_03923 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAPCR_03924 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAPCR_03927 ENOG4105CBT Fructose-1,6-bisphosphatase BAPCR_03930 ENOG4105MMD transcriptional regulator BAPCR_03931 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BAPCR_03932 ENOG4107TXC Transcriptional regulator BAPCR_03933 ENOG41090T1 Membrane BAPCR_03938 ENOG4105FAA peptidase M23 BAPCR_03940 ENOG4105KZD Domain of unknown function (DUF1805) BAPCR_03941 ENOG4107R8B 5'-nucleotidase BAPCR_03944 ENOG4105DIW FeS assembly protein SUFB BAPCR_03945 ENOG4108UNV SUF system FeS assembly protein, NifU family BAPCR_03946 ENOG4105C9B Cysteine desulfurase BAPCR_03947 ENOG4105JRK feS assembly protein SufD BAPCR_03948 ENOG4105C3K feS assembly ATPase SufC BAPCR_03949 ENOG4105D01 (LipO)protein BAPCR_03950 ENOG4105D01 (LipO)protein BAPCR_03951 ENOG4108UMI ABC transporter, permease BAPCR_03957 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAPCR_03966 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPCR_03971 ENOG4108W8B Beta-lactamase domain protein BAPCR_03972 ENOG4105C1G acyl-Coa dehydrogenase BAPCR_03973 ENOG4105CHU acetyl-coa acetyltransferase BAPCR_03976 ENOG4105DZ1 carboxypeptidase BAPCR_03980 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAPCR_03984 ENOG4108SUT Major Facilitator Superfamily BAPCR_03985 ENOG4107R7I amino acid BAPCR_03987 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAPCR_03989 ENOG4107AYK membrAne BAPCR_03996 ENOG4107ZTW SNARE associated Golgi BAPCR_03998 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BAPCR_03999 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_04000 ENOG4105BZU Histidine kinase BAPCR_04002 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAPCR_04005 ENOG4105VG1 fes assembly suf system protein BAPCR_04006 ENOG4105D4Y metalloprotease BAPCR_04010 ENOG4107S91 Sodium hydrogen exchanger BAPCR_04011 ENOG4105NCW Trka-c domain protein BAPCR_04013 ENOG4108RMU ferritin dps family protein BAPCR_04016 ENOG4108URH decarboxylase BAPCR_04021 ENOG4105D9N nucleoside BAPCR_04022 ENOG4105D9N nucleoside BAPCR_04025 ENOG4108RYK Nad-dependent epimerase dehydratase BAPCR_04030 ENOG4105CV8 reductase BAPCR_04031 ENOG4105F27 Major Facilitator BAPCR_04032 ENOG4105KVH Transcriptional regulator BAPCR_04035 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAPCR_04036 ENOG4105D4A Cell wall formation (By similarity) BAPCR_04038 ENOG4105C8Q Methyl-accepting chemotaxis BAPCR_04040 ENOG4105WMR Protein CrcB homolog BAPCR_04041 ENOG4105WMR Protein CrcB homolog BAPCR_04044 ENOG4108MK9 spermidine N(1)-acetyltransferase BAPCR_04045 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BAPCR_04048 ENOG4108IPW abc transporter atp-binding protein BAPCR_04049 ENOG4105CM4 permease protein BAPCR_04055 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAPCR_04057 ENOG4105XZU Preprotein translocase, subunit SecG BAPCR_04058 ENOG41067MG lrgb family BAPCR_04077 ENOG4105EFC phage portal protein HK97 family BAPCR_04081 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPCR_04083 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAPCR_04084 ENOG4105CP7 Triose-phosphate isomerase BAPCR_04089 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_04093 ENOG41090VF Stage v sporulation protein ac BAPCR_04094 ENOG4105CZ3 stage V sporulation protein ad BAPCR_04097 ENOG4105H67 Protein of unknown function (DUF421) BAPCR_04098 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAPCR_04099 ENOG4105KRI phosphocarrier protein (HPr BAPCR_04101 ENOG4105CHW UPF0052 protein BAPCR_04103 ENOG4108Z4K mutator MutT protein BAPCR_04105 ENOG4105C3M thioredoxin reductase BAPCR_04107 ENOG4108S4C acetyltransferase BAPCR_04111 ENOG41086DT Membrane protein of unknown function BAPCR_04113 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPCR_04114 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAPCR_04115 ENOG4105D7V transposase BAPCR_04118 ENOG4107TXC Transcriptional regulator BAPCR_04122 ENOG4105HMI Membrane BAPCR_04123 ENOG4105DUM transcriptional regulator, lysR family BAPCR_04125 ENOG4108WS4 fmn reductase BAPCR_04128 ENOG4105BZ1 (ABC) transporter BAPCR_04130 ENOG4105CN1 protease BAPCR_04131 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAPCR_04132 ENOG4105CAK Cell division ATP-binding protein ftsE BAPCR_04134 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BAPCR_04135 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAPCR_04136 ENOG4105MS2 ribosomal subunit Interface protein BAPCR_04137 ENOG4105VEQ Cold shock protein BAPCR_04138 ENOG41081UC Inherit from COG: Competence protein BAPCR_04141 ENOG4105KVH Transcriptional regulator BAPCR_04143 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAPCR_04144 ENOG4108KGH TRANSCRIPTIONal BAPCR_04145 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAPCR_04146 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAPCR_04147 ENOG4105ESV Glycosyl transferase, family 4 BAPCR_04149 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAPCR_04152 ENOG410901P UPF0249 protein BAPCR_04153 ENOG4105F8D glycoside hydrolase family 4 BAPCR_04154 ENOG4105VCP PTS System BAPCR_04155 ENOG4105CK1 PTS System BAPCR_04157 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAPCR_04158 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAPCR_04159 ENOG4105VCP PTS System BAPCR_04161 ENOG4105VZJ PTS System BAPCR_04164 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BAPCR_04165 ENOG4105ECB domain protein BAPCR_04166 ENOG4107RSM transcriptional regulator BAPCR_04174 ENOG4105DAA L-lactate BAPCR_04176 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BAPCR_04178 ENOG4105E0M Sulfatase BAPCR_04184 ENOG4107R8N Glycosyl transferase, family 2 BAPCR_04186 ENOG4105C94 Transporter BAPCR_04187 ENOG41069ER domain protein BAPCR_04192 ENOG4105KBK Zinc finger, swim domain protein BAPCR_04193 ENOG4105C0D helicase BAPCR_04199 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_04201 ENOG4107RBB ABC transporter, permease BAPCR_04202 ENOG4105C19 ABC transporter BAPCR_04206 ENOG4105CXY transporter BAPCR_04209 ENOG4105BZU Histidine kinase BAPCR_04210 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_04211 ENOG4105CMR udp-glucose 4-epimerase BAPCR_04214 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAPCR_04215 ENOG4105EY8 ABC transporter BAPCR_04224 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAPCR_04226 ENOG4105FRN stage II sporulation protein BAPCR_04229 ENOG4105DY9 regulatoR BAPCR_04230 ENOG4108IUW ABC transporter BAPCR_04234 ENOG4106778 Protein of unknown function (DUF1146) BAPCR_04235 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAPCR_04236 ENOG4105C8S subunit m BAPCR_04237 ENOG4105D65 subunit l BAPCR_04242 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAPCR_04243 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAPCR_04245 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAPCR_04246 ENOG4105BZU Histidine kinase BAPCR_04256 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAPCR_04257 ENOG41062M3 atp synthase BAPCR_04262 ENOG4108YZG isomerase BAPCR_04265 ENOG4108VGI doxx family BAPCR_04266 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAPCR_04269 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAPCR_04271 ENOG4108ZXQ stage ii sporulation protein r BAPCR_04272 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAPCR_04273 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAPCR_04276 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAPCR_04277 ENOG4105CBT Fructose-1,6-bisphosphatase BAPCR_04278 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAPCR_04285 ENOG4105C1G acyl-Coa dehydrogenase BAPCR_04286 ENOG4105C1G acyl-Coa dehydrogenase BAPCR_04287 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAPCR_04289 ENOG4105DF6 Fe-S oxidoreductase BAPCR_04290 ENOG4105DF6 Fe-S oxidoreductase BAPCR_04293 ENOG4105BZU Histidine kinase BAPCR_04298 ENOG4105BZU Histidine kinase BAPCR_04299 ENOG4105KCT ABC transporter BAPCR_04300 ENOG4108M15 ABC transporter BAPCR_04301 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAPCR_04304 ENOG4105IIU Aminopeptidase BAPCR_04308 ENOG4105EMN RNA polymerase sigma factor BAPCR_04310 ENOG410684U Domain of unknown function (DUF1934) BAPCR_04314 ENOG4105CYW agmatinase BAPCR_04316 ENOG4105DXB Major Facilitator superfamily BAPCR_04317 ENOG4107SWG transcriptional regulator MERR family BAPCR_04318 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAPCR_04319 ENOG4105BZ4 penicillin-binding protein BAPCR_04320 ENOG4108XFG YwhD family BAPCR_04321 ENOG4108Z4T Peptidase M50 BAPCR_04322 ENOG41069HH 4-oxalocrotonate tautomerase BAPCR_04323 ENOG4105DCI Phosphohydrolase BAPCR_04324 ENOG4108MES Periplasmic binding protein BAPCR_04325 ENOG4105E0A ABC, transporter BAPCR_04326 ENOG4105EHG Permease protein BAPCR_04327 ENOG4105DQ5 transport system permease protein BAPCR_04329 ENOG4108VCI transcription factor, rsfa family BAPCR_04332 ENOG4108IJ2 phosphate acetyltransferase BAPCR_04335 ENOG4108VKI Cell wall hydrolase BAPCR_04339 ENOG4107SVH Potassium channel protein BAPCR_04341 ENOG410667J hydrolase BAPCR_04342 ENOG4105VCH membrane BAPCR_04344 ENOG4108TU7 Inherit from COG: (ABC) transporter BAPCR_04345 ENOG4105CJ1 ABC, transporter BAPCR_04346 ENOG41090WU lipolytic protein G-D-S-L family BAPCR_04349 ENOG4105D6E homoserine dehydrogenase BAPCR_04354 ENOG4108Y4K DNA-binding transcriptional activator BAPCR_04356 ENOG4105WH1 Two component transcriptional regulator luxr family BAPCR_04357 ENOG4105BZU Histidine kinase BAPCR_04358 ENOG4105BZU Histidine kinase BAPCR_04359 ENOG4105DWF phosphomethylpyrimidine kinase BAPCR_04360 ENOG4105BZU Histidine kinase BAPCR_04361 ENOG4105VCD cytoplasmic protein BAPCR_04362 ENOG4105D22 carbon starvation protein BAPCR_04363 ENOG4105DY9 regulatoR BAPCR_04364 ENOG41079KZ Major Facilitator Superfamily BAPCR_04368 ENOG4105EN6 Membrane BAPCR_04369 ENOG4106YBV Methyl-accepting chemotaxis BAPCR_04370 ENOG4106YBV Methyl-accepting chemotaxis BAPCR_04372 ENOG4108S4H thioesterase Superfamily protein BAPCR_04374 ENOG4105JEU Glycosyl transferase, family 2 BAPCR_04375 ENOG4105C5H ABC transporter BAPCR_04380 ENOG4105CKK Glycosyl transferase, family 2 BAPCR_04381 ENOG41067SE Tetr family transcriptional regulator BAPCR_04383 ENOG4105E0X reductase BAPCR_04384 ENOG4106F5Q Membrane BAPCR_04387 ENOG4105DY9 regulatoR BAPCR_04388 ENOG4108HRK Histidine kinase BAPCR_04389 ENOG4107RGD Major Facilitator superfamily BAPCR_04392 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPCR_04394 ENOG4105IW1 AmiS UreI transporter BAPCR_04396 ENOG4105CMR udp-glucose 4-epimerase BAPCR_04397 ENOG4108UT2 hemolysin iii BAPCR_04399 ENOG4105C1J atp-dependent rna helicase BAPCR_04402 ENOG4105DPN Oligoendopeptidase f BAPCR_04406 ENOG4105C0H protease BAPCR_04407 ENOG4105Q2H domain protein BAPCR_04410 ENOG4105BZU Histidine kinase BAPCR_04411 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_04417 ENOG4105CDU Replicative dna helicase BAPCR_04419 ENOG4105BZR domain protein BAPCR_04420 ENOG4108XMW Membrane BAPCR_04422 ENOG4108UUM single-stranded DNA-binding protein BAPCR_04424 ENOG4105C3G gtp-binding protein BAPCR_04425 ENOG4105VDK protein, conserved in bacteria BAPCR_04426 ENOG4105D8X mechanosensitive ion channel BAPCR_04427 ENOG4108ZDA Sporulation protein YyaC BAPCR_04428 ENOG4105FA0 parb-like partition protein BAPCR_04429 ENOG4107QJE Chromosome Partitioning Protein BAPCR_04433 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAPCR_04435 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAPCR_04439 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAPCR_04440 ENOG410848D S4 domain protein YaaA BAPCR_04443 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAPCR_04450 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAPCR_04457 ENOG4105ZMH deoxynucleoside kinase BAPCR_04459 ENOG4105GTG Isochorismatase BAPCR_04460 ENOG4108Z6B deaminase BAPCR_04461 ENOG4105C6E dna polymerase iii BAPCR_04465 ENOG41067KS pro-sigma K processing BAPCR_04472 ENOG4105CXN decarboxylase BAPCR_04474 ENOG4105FA2 dna polymerase iii BAPCR_04475 ENOG4105MA4 psp1 domain protein BAPCR_04477 ENOG41060K3 Methyltransferase BAPCR_04479 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAPCR_04480 ENOG4105KRN Transcriptional regulator, abrb family BAPCR_04482 ENOG4105F8V Hydrolase, tatD family BAPCR_04483 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BAPCR_04485 ENOG4105XFA sporulation peptidase YabG BAPCR_04486 ENOG4105W42 Veg protein BAPCR_04489 ENOG4105DFT pur operon repressor BAPCR_04490 ENOG4105KME endoribonuclease L-psp BAPCR_04493 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAPCR_04494 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BAPCR_04496 ENOG4108JA2 transcriptioN-repair coupling factor BAPCR_04497 ENOG4108M14 stage v sporulation protein t BAPCR_04499 ENOG4108IY2 MazG family BAPCR_04500 ENOG41082I2 s4 domain protein BAPCR_04501 ENOG4105VYY sporulation protein yabp BAPCR_04504 ENOG41060GV RNA binding s1 domain protein BAPCR_04508 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAPCR_04509 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAPCR_04510 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAPCR_04513 ENOG4105C6T cysteine synthase BAPCR_04514 ENOG4105CRQ synthase (Component I) BAPCR_04515 ENOG4105DDQ anthranilate synthase BAPCR_04516 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAPCR_04517 ENOG4105EEI dihydropteroate synthase BAPCR_04518 ENOG4105KRF dihydroneopterin aldolase BAPCR_04519 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAPCR_04521 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAPCR_04527 ENOG4108Z0C Uvrb UvrC protein BAPCR_04530 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAPCR_04532 ENOG4105CTP PilT protein domain protein BAPCR_04536 ENOG4105D7W serine acetyltransferase BAPCR_04539 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAPCR_04540 ENOG4105M0M Tetracycline resistance protein BAPCR_04541 ENOG4105QIV RNA polymerase BAPCR_04543 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAPCR_04548 ENOG4107Y49 methyltransferase BAPCR_04550 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAPCR_04551 ENOG4105XPM ribosomal protein BAPCR_04572 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAPCR_04577 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAPCR_04579 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAPCR_04581 ENOG41067V7 50S ribosomal protein L36 BAPCR_04587 ENOG4108JJB ABC transporter BAPCR_04588 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAPCR_04589 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAPCR_04594 ENOG4105D1F ATP-binding protein BAPCR_04597 ENOG4108NMV polysaccharide deacetylase BAPCR_04614 ENOG4105C8B TIGR00159 family BAPCR_04615 ENOG4107U5W ybbr family BAPCR_04617 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BAPCR_04618 ENOG4108VQT Alpha beta hydrolase fold protein BAPCR_04620 ENOG4105CMG Carbohydrate kinase BAPCR_04622 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAPCR_04623 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAPCR_04630 ENOG4108PSK reductase BAPCR_04631 ENOG4108UMI ABC transporter, permease BAPCR_04632 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_04633 ENOG4105D01 (LipO)protein BAPCR_04634 ENOG4105EE1 crotonyl-CoA reductase BAPCR_04636 ENOG4105IQ5 FAD linked oxidase domain protein BAPCR_04637 ENOG4105IQ5 FAD linked oxidase domain protein BAPCR_04640 ENOG4105C2C drug resistance transporter, Bcr CflA BAPCR_04643 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPCR_04644 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPCR_04645 ENOG4105C3U ABC transporter BAPCR_04646 ENOG4108JQ7 (ABC) transporter BAPCR_04652 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPCR_04653 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPCR_04655 ENOG4105II7 pyrroline-5-carboxylate reductase BAPCR_04656 ENOG4107XDY Nicotinamide Mononucleotide Transporter BAPCR_04658 ENOG4105E0C molybdate abc transporter BAPCR_04659 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAPCR_04660 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAPCR_04663 ENOG4105EGI Transcriptional regulator BAPCR_04667 ENOG4105F6E Acyl-transferase BAPCR_04671 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAPCR_04674 ENOG4108RE7 deoxyribonuclease BAPCR_04675 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAPCR_04679 ENOG4105C5H ABC transporter BAPCR_04682 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BAPCR_04684 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPCR_04685 ENOG4105C3U ABC transporter BAPCR_04686 ENOG4108JQ7 (ABC) transporter BAPCR_04687 ENOG410667J hydrolase BAPCR_04692 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BAPCR_04693 ENOG4105ERH Fumarylacetoacetate hydrolase BAPCR_04695 ENOG4108SC4 )-transporter BAPCR_04696 ENOG4105CPF Cell wall formation (By similarity) BAPCR_04697 ENOG4105CPF Cell wall formation (By similarity) BAPCR_04698 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAPCR_04701 ENOG4107ZXI Rhomboid family BAPCR_04703 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAPCR_04704 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAPCR_04706 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAPCR_04725 ENOG4105K8N protein family UPF0079, ATPase BAPCR_04726 ENOG41072GX Peptidase M22 Glycoprotease BAPCR_04727 ENOG410801F ribosomal-protein-alanine acetyltransferase BAPCR_04728 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAPCR_04729 ENOG4105C5H ABC transporter BAPCR_04732 ENOG4108TYN CAAX amino terminal protease family protein BAPCR_04736 ENOG4105C7N Xanthine uracil vitamin C permease BAPCR_04738 ENOG4105BZU Histidine kinase BAPCR_04742 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPCR_04746 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_04750 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAPCR_04751 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAPCR_04752 ENOG4105C83 adenylosuccinate lyase BAPCR_04754 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAPCR_04759 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAPCR_04761 ENOG4105C12 Phosphoribosylglycinamide synthetase BAPCR_04766 ENOG4105C4R Atp-dependent dna helicase BAPCR_04772 ENOG4108W2Y isochorismatase BAPCR_04773 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_04774 ENOG4108UMI ABC transporter, permease BAPCR_04775 ENOG4105D01 (LipO)protein BAPCR_04779 ENOG4105D0U Arsenite-activated ATPase (ArsA) BAPCR_04780 ENOG410834F Transcriptional regulator BAPCR_04781 ENOG4107I77 yiaA/B two helix domain BAPCR_04785 ENOG4105CBD Diacylglycerol kinase BAPCR_04786 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAPCR_04787 ENOG4108JPW Aminotransferase BAPCR_04789 ENOG4105C26 Dehydrogenase BAPCR_04790 ENOG4105KPY Small multidrug resistance protein BAPCR_04794 ENOG4105D9N nucleoside BAPCR_04795 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAPCR_04798 ENOG4108W15 Protein of unknown function (DUF1456) BAPCR_04801 ENOG4105DTQ mandelate racemase muconate lactonizing BAPCR_04803 ENOG4105DFD Na H antiporter BAPCR_04807 ENOG4105D3R alkyl hydroperoxide reductase BAPCR_04808 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BAPCR_04810 ENOG4107W7X Aldolase BAPCR_04811 ENOG4105EHG Permease protein BAPCR_04812 ENOG4105DQ5 transport system permease protein BAPCR_04813 ENOG4108V5C ABC transporter BAPCR_04817 ENOG4106UIA BAPCR_04818 ENOG4106UIA BAPCR_04822 ENOG4105BZU Histidine kinase BAPCR_04826 ENOG410756H nucleotidyltransferase BAPCR_04827 ENOG4105D2S major facilitator superfamily BAPCR_04830 ENOG4105E5Q amino acid AbC transporter BAPCR_04831 ENOG4105EAB amino acid AbC transporter BAPCR_04833 ENOG4105C8Q Methyl-accepting chemotaxis BAPCR_04834 ENOG4105C8Q Methyl-accepting chemotaxis BAPCR_04836 ENOG4105CI1 PTS System BAPCR_04842 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAPCR_04845 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAPCR_04848 ENOG4105C5H ABC transporter BAPCR_04855 ENOG41062JF Transcriptional regulator BAPCR_04859 ENOG4105DEU major facilitator superfamily BAPCR_04862 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BAPCR_04865 ENOG4108N0M stress protein BAPCR_04866 ENOG4106FN3 tellurium resistance protein BAPCR_04867 ENOG4106FN3 tellurium resistance protein BAPCR_04868 ENOG4107TS3 membrane protein, TerC BAPCR_04869 ENOG4108TTB tellurium resistance protein BAPCR_04873 ENOG4105KJF protein tyrosine phosphatase BAPCR_04875 ENOG4107U9T Pfam:Ribonuclease_BN BAPCR_04876 ENOG4105C59 p-type ATPase BAPCR_04877 ENOG4108IPJ Membrane BAPCR_04879 ENOG4105C3F Signal peptidase i BAPCR_04882 ENOG4107ZTW SNARE associated Golgi BAPCR_04885 ENOG410606W general stress protein BAPCR_04886 ENOG4105UPD Calcium Proton BAPCR_04894 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAPCR_04895 ENOG4105VTR Integrase BAPCR_04953 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAPCR_04955 ENOG4108JUB Transcriptional regulator BAPCR_04957 ENOG4108IQI permease BAPCR_04963 ENOG4105CSV Glutaminase BAPCR_04965 ENOG4108A04 Beta-lactamase BAPCR_04968 ENOG4105CKK Glycosyl transferase, family 2 BAPCR_04970 ENOG4107QQG Dehydrogenase BAPCR_04971 ENOG4105C3I Nad-dependent epimerase dehydratase BAPCR_04974 ENOG4105F1A Pyruvate formate-lyase BAPCR_04978 ENOG4105CI2 imidazolone-5-propionate hydrolase BAPCR_04979 ENOG4105ECP epimerase BAPCR_04985 ENOG41067AE Membrane-bound metal-dependent hydrolase BAPCR_04986 ENOG4105CEN a g-specific adenine glycosylase BAPCR_04987 ENOG4106BXE BAPCR_04991 ENOG4105BZ1 (ABC) transporter BAPCR_04992 ENOG4107NBY Membrane BAPCR_04993 ENOG4105CBC glutamate synthase BAPCR_04995 ENOG4108IUW ABC transporter BAPCR_04999 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAPCR_05000 ENOG4105G5W regulator Fur family BAPCR_05023 ENOG4108JQC penicillin-binding protein 1A BAPCR_05024 ENOG4107ZQN disulfide bond BAPCR_05026 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAPCR_05028 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAPCR_05029 ENOG4105BZU Histidine kinase BAPCR_05031 ENOG4105CYN Serine protein kinase BAPCR_05035 ENOG4105C94 Transporter BAPCR_05038 ENOG4105DZ6 Band 7 protein BAPCR_05040 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAPCR_05041 ENOG4108MRH transcriptional regulatory protein BAPCR_05042 ENOG4105D4T Citrate transporter BAPCR_05046 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAPCR_05047 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPCR_05048 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAPCR_05049 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BAPCR_05051 ENOG4105BZ7 extracellular solute-binding protein family 1 BAPCR_05052 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BAPCR_05053 ENOG4108STX response regulator BAPCR_05054 ENOG4105US7 Histidine kinase BAPCR_05059 ENOG4108MRH transcriptional regulatory protein BAPCR_05061 ENOG4105C6K Malic enzyme BAPCR_05063 ENOG4108UZ3 Transporter BAPCR_05064 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAPCR_05066 ENOG4105BZU Histidine kinase BAPCR_05067 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPCR_05069 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAPCR_05070 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAPCR_05071 ENOG4108JB9 formate dehydrogenase BAPCR_05076 ENOG4105CUB amino acid BAPCR_05078 ENOG4105C59 p-type ATPase BAPCR_05079 ENOG4105DAP Nicotinate phosphoribosyltransferase BAPCR_05086 ENOG41073R8 VanW family BAPCR_05087 ENOG4108KGH TRANSCRIPTIONal BAPCR_05088 ENOG4105D9N nucleoside BAPCR_05089 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAPCR_05090 ENOG4105C37 (CBS) domain BAPCR_05091 ENOG4108IJ0 Aspartate ammonia-lyase BAPCR_05092 ENOG4105DAA L-lactate BAPCR_05095 ENOG4105DUX Transporter BAPCR_05096 ENOG4108MES Periplasmic binding protein BAPCR_05097 ENOG4105DQ5 transport system permease protein BAPCR_05098 ENOG4108IHU transport system permease protein BAPCR_05099 ENOG4105E0A ABC, transporter BAPCR_05100 ENOG4105DMQ Methyltransferase BAPCR_05102 ENOG4105EXW epimerase dehydratase BAPCR_05104 ENOG4107T89 von Willebrand factor, type A BAPCR_05105 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAPCR_05106 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPCR_05109 ENOG4105BZU Histidine kinase BAPCR_05110 ENOG4105D5Q Arginine ornithine antiporter BAPCR_05111 ENOG4107414 GntR family transcriptional regulator BAPCR_05112 ENOG4105C5Y PTS System BAPCR_05113 ENOG4105CG3 alpha amylase, catalytic region BAPCR_05117 ENOG4105E1K spore germination protein BAPCR_05119 ENOG4105CRN Aminoglycoside phosphotransferase BAPCR_05120 ENOG4105BZG amino acid carrier protein BAPCR_05121 ENOG4105CDA abc transporter atp-binding protein BAPCR_05122 ENOG4105CT1 (ABC) transporter BAPCR_05123 ENOG4105EAD ABC transporter BAPCR_05124 ENOG4105DRP amino acid AbC transporter BAPCR_05125 ENOG4108IQI permease BAPCR_05130 ENOG4105D29 Helix-turn-helix type 11 domain protein BAPCR_05131 ENOG4105NAE bifunctional deaminase-reductase domain protein BAPCR_05132 ENOG4105BZU Histidine kinase BAPCR_05135 ENOG4105CHH sulfate transporter BAPCR_05136 ENOG41068KF Universal stress protein BAPCR_05138 ENOG4105DEF Extracellular solute-binding protein, family 5 BAPCR_05140 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPCR_05141 ENOG4108JQ7 (ABC) transporter BAPCR_05143 ENOG4105CXY transporter BAPCR_05144 ENOG41067TZ transcriptional regulator, MarR family BAPCR_05145 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_05146 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_05147 ENOG4105ETE Transcriptional regulator (LacI family BAPCR_05148 ENOG4108RVA ribokinase BAPCR_05150 ENOG4105C2J ABC transporter BAPCR_05151 ENOG4105CNN ABC, transporter BAPCR_05152 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAPCR_05153 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAPCR_05165 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPCR_05166 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAPCR_05167 ENOG41069ER domain protein BAPCR_05168 ENOG4105VZ8 Transcriptional regulator BAPCR_05169 ENOG4107D63 BAPCR_05171 ENOG4105DUX Transporter BAPCR_05175 ENOG4105C85 amino acid BAPCR_05176 ENOG4105C7N Xanthine uracil vitamin C permease BAPCR_05184 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAPCR_05185 ENOG4105E2S oxidase) subunit II BAPCR_05188 ENOG4106CAD Protein of unknown function (DUF3311) BAPCR_05189 ENOG4105E1V na solute symporter BAPCR_05192 ENOG4108NHD germination protein BAPCR_05193 ENOG4105CE1 Ferrous iron transport protein b BAPCR_05194 ENOG4105CE1 Ferrous iron transport protein b BAPCR_05195 ENOG4105CE1 Ferrous iron transport protein b BAPCR_05196 ENOG4105CVA phosphate BAPCR_05197 ENOG4105C8U phosphate abc transporter BAPCR_05198 ENOG4105E2Z phosphate ABC transporter (Permease BAPCR_05224 ENOG41080XQ Signal transduction protein with cbs domains BAPCR_05229 ENOG4105ETU transcriptional activator (TenA BAPCR_05231 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAPCR_05233 ENOG4108VEU Thiamine monophosphate synthase BAPCR_05234 ENOG41080HI glycine oxidase BAPCR_05237 ENOG4105D06 uba thif-type nad fad binding protein BAPCR_05238 ENOG4105DWF phosphomethylpyrimidine kinase BAPCR_05247 ENOG4108INS Transcriptional regulator BAPCR_05250 ENOG4105C7N Xanthine uracil vitamin C permease BAPCR_05252 ENOG4108PXI ErfK YbiS YcfS YnhG BAPCR_05256 ENOG4105C5Y PTS System BAPCR_05263 ENOG4108B31 Spore germination protein BAPCR_05267 ENOG4107Y03 Nitroreductase BAPCR_05268 ENOG4105ED1 spovr family BAPCR_05273 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BAPCR_05274 ENOG4105XTG Pfam:DUF156 BAPCR_05275 ENOG4105VFE sira family BAPCR_05276 ENOG4107TPS domain protein BAPCR_05277 ENOG4107TPS domain protein BAPCR_05278 ENOG4105VFE sira family BAPCR_05280 ENOG41085GJ domain protein BAPCR_05282 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BAPCR_05283 ENOG41087NI Sulfite exporter TauE/SafE BAPCR_05285 ENOG4108KGH TRANSCRIPTIONal BAPCR_05290 ENOG4105EMD TRANSCRIPTIONal BAPCR_05291 ENOG4105VCP PTS System BAPCR_05292 ENOG4105VZJ PTS System BAPCR_05296 ENOG41069ER domain protein BAPCR_05297 ENOG4107RBB ABC transporter, permease BAPCR_05298 ENOG4105C19 ABC transporter BAPCR_05304 ENOG4105WEF catalase BAPCR_05311 ENOG4107T5V SNARE associated Golgi BAPCR_05318 ENOG4105CUB amino acid BAPCR_05319 ENOG4107RWR Sodium hydrogen exchanger BAPCR_05321 ENOG4106KNT transcriptional regulator BAPCR_05328 ENOG4108PCN EamA-like transporter family BAPCR_05329 ENOG4108YXU transcriptional regulator AsnC family BAPCR_05331 ENOG4105KPY Small multidrug resistance protein BAPCR_05332 ENOG4105KPY Small multidrug resistance protein BAPCR_05337 ENOG4105NF4 modulator of drug activity BAPCR_05338 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAPCR_05339 ENOG410605W Major Facilitator BAPCR_05341 ENOG4107RKG DJ-1/PfpI family BAPCR_05342 ENOG4105CH6 catalase BAPCR_05344 ENOG4105D5Q Arginine ornithine antiporter BAPCR_05345 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAPCR_05347 ENOG4105C26 Dehydrogenase BAPCR_05348 ENOG4105BZ1 (ABC) transporter BAPCR_05349 ENOG4105BZ1 (ABC) transporter BAPCR_05350 ENOG4105BZ1 (ABC) transporter BAPCR_05352 ENOG4105DRP amino acid AbC transporter BAPCR_05353 ENOG4105CDA abc transporter atp-binding protein BAPCR_05356 ENOG410839P BAPCR_05363 ENOG4107FQX Alpha-acetolactate decarboxylase BAPCR_05368 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPCR_05370 ENOG4105D4P Coproporphyrinogen iii oxidase BAPCR_05373 ENOG4105CHH sulfate transporter BAPCR_05381 ENOG4106AKK s-layer domain-containing protein BAPCR_05383 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPCR_05384 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPCR_05387 ENOG4105CGU Enoyl-CoA hydratase BAPCR_05390 ENOG4105DER m42 family BAPCR_05394 ENOG4105CTU Proline racemase BAPCR_05402 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPCR_05405 ENOG4108JQ7 (ABC) transporter BAPCR_05411 ENOG4105CSH Transporter BAPCR_05413 ENOG4108MRH transcriptional regulatory protein BAPCR_05422 ENOG4105CDU Replicative dna helicase BAPCR_05430 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_05441 ENOG4107P5I polyketide synthase BAPCR_05442 ENOG4108IG5 Transcriptional regulator BAPCR_05446 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAPCR_05450 ENOG4105CMT Dihydroxyacetone kinase BAPCR_05452 ENOG4105CMT Dihydroxyacetone kinase BAPCR_05453 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAPCR_05454 ENOG410847I Transcriptional regulator, BadM Rrf2 family BAPCR_05459 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BAPCR_05473 ENOG4105WN5 stage II sporulation protein BAPCR_05475 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPCR_05477 ENOG4108MJI response regulator BAPCR_05478 ENOG4105BZU Histidine kinase BAPCR_05479 ENOG4105BZU Histidine kinase BAPCR_05484 ENOG4105K8R UPF0145 protein BAPCR_05490 ENOG4107VRP DNA repair exonuclease BAPCR_05491 ENOG4106D4I domain protein BAPCR_05492 ENOG4105D7V transposase BAPCR_05495 ENOG4108IND Tetr family transcriptional regulator BAPCR_05496 ENOG4105EQ0 Major Facilitator superfamily BAPCR_05500 ENOG4108MUZ hydrolase BAPCR_05505 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAPCR_05508 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAPCR_05511 ENOG4105EMN RNA polymerase sigma factor BAPCR_05516 ENOG4105C57 major facilitator superfamily BAPCR_05517 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPCR_05519 ENOG4105EEM helicase BAPCR_05520 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPCR_05525 ENOG4105K59 histidine triad (HIT) protein BAPCR_05533 ENOG410905X membrane-flanked domain protein BAPCR_05535 ENOG4105CKV Membrane BAPCR_05544 ENOG410905X membrane-flanked domain protein BAPCR_05545 ENOG4105CKV Membrane BAPCR_05546 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAPCR_05547 ENOG4105BZ4 penicillin-binding protein BAPCR_05548 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAPCR_05550 ENOG4105C1Q protoporphyrinogen oxidase BAPCR_05555 ENOG4105NA0 Transcriptional regulator BAPCR_05558 ENOG4105ECB domain protein BAPCR_05564 ENOG4106AXD BAPCR_05565 ENOG4108RQ5 Beta-lactamase domain-containing protein BAPCR_05566 ENOG4105DF9 Lipoate-protein, ligase BAPCR_05568 ENOG4105CEY Amp-dependent synthetase and ligase BAPCR_05574 ENOG4105CNA YD repeat protein BAPCR_05579 ENOG4105ENX hydrolase BAPCR_05581 ENOG4107RN3 metallophosphoesterase BAPCR_05582 ENOG4107TVP HD domain protein BAPCR_05584 ENOG4108AEY RNA polymerase sigma factor BAPCR_05585 ENOG41086D8 Transcriptional regulator BAPCR_05589 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPCR_05593 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAPCR_05594 ENOG4105C8Q Methyl-accepting chemotaxis BAPCR_pXO1-00009 ENOG4105EKQ RNA-directed DNA polymerase BAPCR_pXO1-00031 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAPCR_pXO1-00038 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BAPCR_pXO1-00040 ENOG4108MEK Metal-binding protein YodA BAPCR_pXO1-00044 ENOG4105DQ6 Transposase BAPCR_pXO1-00046 ENOG4105DQ6 Transposase BAPCR_pXO1-00049 ENOG4105DQ6 Transposase BAPCR_pXO1-00050 ENOG4105DQ6 Transposase BAPCR_pXO1-00052 ENOG4108IBT Inherit from COG: transposase BAPCR_pXO1-00059 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPCR_pXO1-00061 ENOG4105KRN Transcriptional regulator, abrb family BAPCR_pXO1-00085 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAPCR_pXO1-00091 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BAPCR_pXO1-00101 ENOG4105DQ6 Transposase BAPCR_pXO1-00105 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAPCR_pXO1-00106 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAPCR_pXO1-00109 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAPCR_pXO1-00110 ENOG4106AKK s-layer domain-containing protein BAPCR_pXO1-00116 ENOG4105DHF Membrane BAPCR_pXO1-00165 ENOG4105CNU cell division protein FtsK BAPCR_pXO1-00178 ENOG4106JUT Streptomycin 3''-adenylyltransferase BAPCR_pXO1-00190 ENOG4105EKQ RNA-directed DNA polymerase BAPCR_pXO2-00003 ENOG4105C3F Signal peptidase i BAPCR_pXO2-00010 ENOG4105N14 lysine exporter protein LysE YggA BAPCR_pXO2-00016 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPCR_pXO2-00020 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPCR_pXO2-00031 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPCR_pXO2-00032 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPCR_pXO2-00046 ENOG4105K4H Nlp p60 protein BAPCR_pXO2-00081 ENOG4107QJE Chromosome Partitioning Protein BAPCR_pXO2-00085 ENOG4105DQ6 Transposase BAPCR_pXO2-00092 ENOG4105EWC Purine nucleoside phosphorylase