locus-tag class description AOD60_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AOD60_00015 ENOG410848D S4 domain protein YaaA AOD60_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AOD60_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AOD60_00100 ENOG4105ZMH deoxynucleoside kinase AOD60_00110 ENOG4105GTG Isochorismatase AOD60_00120 ENOG4108Z6B deaminase AOD60_00125 ENOG4105C6E dna polymerase iii AOD60_00145 ENOG41067KS pro-sigma K processing AOD60_00180 ENOG4105CXN decarboxylase AOD60_00190 ENOG4105FA2 dna polymerase iii AOD60_00195 ENOG4105MA4 psp1 domain protein AOD60_00205 ENOG41060K3 Methyltransferase AOD60_00215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AOD60_00220 ENOG4105KRN Transcriptional regulator, abrb family AOD60_00230 ENOG4105F8V Hydrolase, tatD family AOD60_00235 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) AOD60_00245 ENOG4105XFA sporulation peptidase YabG AOD60_00250 ENOG4105W42 Veg protein AOD60_00265 ENOG4105DFT pur operon repressor AOD60_00270 ENOG4105KME endoribonuclease L-psp AOD60_00285 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AOD60_00290 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AOD60_00300 ENOG4108JA2 transcriptioN-repair coupling factor AOD60_00305 ENOG4108M14 stage v sporulation protein t AOD60_00315 ENOG4108IY2 MazG family AOD60_00320 ENOG41082I2 s4 domain protein AOD60_00325 ENOG4105VYY sporulation protein yabp AOD60_00340 ENOG41060GV RNA binding s1 domain protein AOD60_00360 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AOD60_00365 ENOG4108UGV hypoxanthine phosphoribosyltransferase AOD60_00370 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AOD60_00385 ENOG4105C6T cysteine synthase AOD60_00390 ENOG4105CRQ synthase (Component I) AOD60_00395 ENOG4105DDQ anthranilate synthase AOD60_00400 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 AOD60_00405 ENOG4105EEI dihydropteroate synthase AOD60_00410 ENOG4105KRF dihydroneopterin aldolase AOD60_00415 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AOD60_00425 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AOD60_00455 ENOG4108Z0C Uvrb UvrC protein AOD60_00470 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AOD60_00480 ENOG4105CTP PilT protein domain protein AOD60_00500 ENOG4105D7W serine acetyltransferase AOD60_00515 ENOG4105C2N RNA methyltransferase TrmH family group 3 AOD60_00520 ENOG4105M0M Tetracycline resistance protein AOD60_00525 ENOG4105QIV RNA polymerase AOD60_00540 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AOD60_00565 ENOG4107Y49 methyltransferase AOD60_00575 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AOD60_00580 ENOG4105XPM ribosomal protein AOD60_00685 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AOD60_00710 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AOD60_00720 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AOD60_00730 ENOG41067V7 50S ribosomal protein L36 AOD60_00760 ENOG4108JJB ABC transporter AOD60_00765 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) AOD60_00770 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AOD60_00795 ENOG4105D1F ATP-binding protein AOD60_00810 ENOG4108NMV polysaccharide deacetylase AOD60_00895 ENOG4105C8B TIGR00159 family AOD60_00900 ENOG4107U5W ybbr family AOD60_00915 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AOD60_00920 ENOG4108VQT Alpha beta hydrolase fold protein AOD60_00940 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AOD60_00945 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein AOD60_00980 ENOG4108PSK reductase AOD60_00985 ENOG4108UMI ABC transporter, permease AOD60_00990 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOD60_00995 ENOG4105D01 (LipO)protein AOD60_01000 ENOG4105EE1 crotonyl-CoA reductase AOD60_01010 ENOG4105IQ5 FAD linked oxidase domain protein AOD60_01025 ENOG4105C2C drug resistance transporter, Bcr CflA AOD60_01040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOD60_01045 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOD60_01050 ENOG4105C3U ABC transporter AOD60_01055 ENOG4108JQ7 (ABC) transporter AOD60_01085 ENOG4108J59 Extracellular solute-binding protein, family 5 AOD60_01090 ENOG4108J59 Extracellular solute-binding protein, family 5 AOD60_01100 ENOG4105II7 pyrroline-5-carboxylate reductase AOD60_01110 ENOG4107XDY Nicotinamide Mononucleotide Transporter AOD60_01120 ENOG4105E0C molybdate abc transporter AOD60_01125 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOD60_01130 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOD60_01135 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family AOD60_01150 ENOG4105EGI Transcriptional regulator AOD60_01165 ENOG4105F6E Acyl-transferase AOD60_01185 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) AOD60_01200 ENOG4108RE7 deoxyribonuclease AOD60_01205 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) AOD60_01230 ENOG4105C5H ABC transporter AOD60_01245 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein AOD60_01255 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOD60_01260 ENOG4105C3U ABC transporter AOD60_01265 ENOG4108JQ7 (ABC) transporter AOD60_01290 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase AOD60_01295 ENOG4105ERH Fumarylacetoacetate hydrolase AOD60_01305 ENOG4108SC4 )-transporter AOD60_01310 ENOG4105CPF Cell wall formation (By similarity) AOD60_01315 ENOG4105CPF Cell wall formation (By similarity) AOD60_01320 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) AOD60_01335 ENOG4107ZXI Rhomboid family AOD60_01345 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein AOD60_01350 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AOD60_01360 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) AOD60_01460 ENOG4105K8N protein family UPF0079, ATPase AOD60_01465 ENOG41072GX Peptidase M22 Glycoprotease AOD60_01470 ENOG410801F ribosomal-protein-alanine acetyltransferase AOD60_01475 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AOD60_01480 ENOG4105C5H ABC transporter AOD60_01495 ENOG4108TYN CAAX amino terminal protease family protein AOD60_01515 ENOG4105C7N Xanthine uracil vitamin C permease AOD60_01525 ENOG4105BZU Histidine kinase AOD60_01555 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOD60_01595 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOD60_01615 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_01635 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AOD60_01640 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AOD60_01645 ENOG4105C83 adenylosuccinate lyase AOD60_01655 ENOG4105VR9 phosphoribosylformylglycinamidine synthase AOD60_01680 ENOG4108V3E phosphoribosylglycinamide formyltransferase AOD60_01690 ENOG4105C12 Phosphoribosylglycinamide synthetase AOD60_01715 ENOG4105C4R Atp-dependent dna helicase AOD60_01745 ENOG4108W2Y isochorismatase AOD60_01750 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOD60_01755 ENOG4108UMI ABC transporter, permease AOD60_01760 ENOG4105D01 (LipO)protein AOD60_01780 ENOG410834F Transcriptional regulator AOD60_01805 ENOG4105CBD Diacylglycerol kinase AOD60_01810 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AOD60_01815 ENOG4108JPW Aminotransferase AOD60_01825 ENOG4105C26 Dehydrogenase AOD60_01830 ENOG4105KPY Small multidrug resistance protein AOD60_01850 ENOG4105D9N nucleoside AOD60_01855 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AOD60_01870 ENOG4108W15 Protein of unknown function (DUF1456) AOD60_01885 ENOG4105DTQ mandelate racemase muconate lactonizing AOD60_01895 ENOG4105DFD Na H antiporter AOD60_01915 ENOG4105D3R alkyl hydroperoxide reductase AOD60_01920 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) AOD60_01930 ENOG4107W7X Aldolase AOD60_01935 ENOG4105EHG Permease protein AOD60_01940 ENOG4105DQ5 transport system permease protein AOD60_01945 ENOG4108V5C ABC transporter AOD60_01970 ENOG4106UIA AOD60_01975 ENOG4106UIA AOD60_02000 ENOG4105BZU Histidine kinase AOD60_02020 ENOG410756H nucleotidyltransferase AOD60_02025 ENOG4105D2S major facilitator superfamily AOD60_02040 ENOG4105E5Q amino acid AbC transporter AOD60_02045 ENOG4105EAB amino acid AbC transporter AOD60_02060 ENOG4105C8Q Methyl-accepting chemotaxis AOD60_02065 ENOG4105C8Q Methyl-accepting chemotaxis AOD60_02075 ENOG4105CI1 PTS System AOD60_02105 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AOD60_02120 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AOD60_02135 ENOG4105C5H ABC transporter AOD60_02160 ENOG41062JF Transcriptional regulator AOD60_02180 ENOG4105DEU major facilitator superfamily AOD60_02195 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) AOD60_02210 ENOG4108N0M stress protein AOD60_02215 ENOG4106FN3 tellurium resistance protein AOD60_02220 ENOG4106FN3 tellurium resistance protein AOD60_02225 ENOG4107TS3 membrane protein, TerC AOD60_02230 ENOG4108TTB tellurium resistance protein AOD60_02250 ENOG4105KJF protein tyrosine phosphatase AOD60_02260 ENOG4107U9T Pfam:Ribonuclease_BN AOD60_02265 ENOG4105C59 p-type ATPase AOD60_02270 ENOG4108IPJ Membrane AOD60_02290 ENOG4107ZTW SNARE associated Golgi AOD60_02305 ENOG410606W general stress protein AOD60_02310 ENOG4105UPD Calcium Proton AOD60_02350 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AOD60_02355 ENOG4105VTR Integrase AOD60_02360 ENOG4108IMY Transcriptional regulator AOD60_02635 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AOD60_02645 ENOG4108JUB Transcriptional regulator AOD60_02655 ENOG4108IQI permease AOD60_02690 ENOG4105CSV Glutaminase AOD60_02700 ENOG4108A04 Beta-lactamase AOD60_02715 ENOG4105CKK Glycosyl transferase, family 2 AOD60_02725 ENOG4107QQG Dehydrogenase AOD60_02730 ENOG4105C3I Nad-dependent epimerase dehydratase AOD60_02750 ENOG4105F1A Pyruvate formate-lyase AOD60_02770 ENOG4105CI2 imidazolone-5-propionate hydrolase AOD60_02775 ENOG4105ECP epimerase AOD60_02805 ENOG41067AE Membrane-bound metal-dependent hydrolase AOD60_02810 ENOG4105CEN a g-specific adenine glycosylase AOD60_02815 ENOG4106BXE AOD60_02835 ENOG4105BZ1 (ABC) transporter AOD60_02840 ENOG4107NBY Membrane AOD60_02845 ENOG4105CBC glutamate synthase AOD60_02855 ENOG4108IUW ABC transporter AOD60_02875 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AOD60_02880 ENOG4105G5W regulator Fur family AOD60_02995 ENOG4108JQC penicillin-binding protein 1A AOD60_03000 ENOG4107ZQN disulfide bond AOD60_03010 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AOD60_03020 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AOD60_03025 ENOG4105BZU Histidine kinase AOD60_03035 ENOG4105CYN Serine protein kinase AOD60_03060 ENOG4105C94 Transporter AOD60_03075 ENOG4105DZ6 Band 7 protein AOD60_03085 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AOD60_03095 ENOG4105D4T Citrate transporter AOD60_03115 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator AOD60_03120 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOD60_03125 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AOD60_03130 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component AOD60_03135 ENOG4105BZ7 extracellular solute-binding protein family 1 AOD60_03140 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AOD60_03145 ENOG4108STX response regulator AOD60_03150 ENOG4105US7 Histidine kinase AOD60_03175 ENOG4108MRH transcriptional regulatory protein AOD60_03185 ENOG4105C6K Malic enzyme AOD60_03195 ENOG4108UZ3 Transporter AOD60_03200 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AOD60_03210 ENOG4105BZU Histidine kinase AOD60_03215 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_03225 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) AOD60_03230 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AOD60_03235 ENOG4108JB9 formate dehydrogenase AOD60_03255 ENOG4105CUB amino acid AOD60_03265 ENOG4105C59 p-type ATPase AOD60_03270 ENOG4105DAP Nicotinate phosphoribosyltransferase AOD60_03300 ENOG41073R8 VanW family AOD60_03305 ENOG4108KGH TRANSCRIPTIONal AOD60_03310 ENOG4105D9N nucleoside AOD60_03315 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AOD60_03320 ENOG4105C37 (CBS) domain AOD60_03325 ENOG4108IJ0 Aspartate ammonia-lyase AOD60_03330 ENOG4105DAA L-lactate AOD60_03345 ENOG4105DUX Transporter AOD60_03350 ENOG4108MES Periplasmic binding protein AOD60_03355 ENOG4105DQ5 transport system permease protein AOD60_03360 ENOG4108IHU transport system permease protein AOD60_03365 ENOG4105E0A ABC, transporter AOD60_03370 ENOG4105DMQ Methyltransferase AOD60_03390 ENOG4107T89 von Willebrand factor, type A AOD60_03395 ENOG4105GMT ATPase associated with various cellular activities aaa_5 AOD60_03400 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOD60_03415 ENOG4105BZU Histidine kinase AOD60_03420 ENOG4105D5Q Arginine ornithine antiporter AOD60_03425 ENOG4107414 GntR family transcriptional regulator AOD60_03430 ENOG4105C5Y PTS System AOD60_03435 ENOG4105CG3 alpha amylase, catalytic region AOD60_03450 ENOG4105E1K spore germination protein AOD60_03460 ENOG4105CRN Aminoglycoside phosphotransferase AOD60_03465 ENOG4105BZG amino acid carrier protein AOD60_03470 ENOG4105CDA abc transporter atp-binding protein AOD60_03475 ENOG4105CT1 (ABC) transporter AOD60_03480 ENOG4105EAD ABC transporter AOD60_03485 ENOG4105DRP amino acid AbC transporter AOD60_03490 ENOG4108IQI permease AOD60_03515 ENOG4105D29 Helix-turn-helix type 11 domain protein AOD60_03520 ENOG4105NAE bifunctional deaminase-reductase domain protein AOD60_03525 ENOG4105BZU Histidine kinase AOD60_03540 ENOG4105CHH sulfate transporter AOD60_03545 ENOG41068KF Universal stress protein AOD60_03555 ENOG4105DEF Extracellular solute-binding protein, family 5 AOD60_03565 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOD60_03570 ENOG4108JQ7 (ABC) transporter AOD60_03575 ENOG4105C3U ABC transporter AOD60_03580 ENOG4105CXY transporter AOD60_03585 ENOG41067TZ transcriptional regulator, MarR family AOD60_03590 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_03595 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_03600 ENOG4105ETE Transcriptional regulator (LacI family AOD60_03605 ENOG4108RVA ribokinase AOD60_03615 ENOG4105C2J ABC transporter AOD60_03620 ENOG4105CNN ABC, transporter AOD60_03625 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AOD60_03630 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AOD60_03690 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOD60_03695 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer AOD60_03700 ENOG41069ER domain protein AOD60_03705 ENOG4105VZ8 Transcriptional regulator AOD60_03710 ENOG4107D63 AOD60_03720 ENOG4105DUX Transporter AOD60_03740 ENOG4105C85 amino acid AOD60_03745 ENOG4105C7N Xanthine uracil vitamin C permease AOD60_03785 ENOG4105BZ9 Cytochrome C oxidase, subunit I AOD60_03790 ENOG4105E2S oxidase) subunit II AOD60_03795 ENOG4108IQI permease AOD60_03810 ENOG4106CAD Protein of unknown function (DUF3311) AOD60_03815 ENOG4105E1V na solute symporter AOD60_03830 ENOG4108NHD germination protein AOD60_03840 ENOG4105CE1 Ferrous iron transport protein b AOD60_03845 ENOG4105CE1 Ferrous iron transport protein b AOD60_03850 ENOG4105CE1 Ferrous iron transport protein b AOD60_03855 ENOG4105CVA phosphate AOD60_03860 ENOG4105C8U phosphate abc transporter AOD60_03865 ENOG4105E2Z phosphate ABC transporter (Permease AOD60_03990 ENOG41080XQ Signal transduction protein with cbs domains AOD60_04015 ENOG4105ETU transcriptional activator (TenA AOD60_04025 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AOD60_04035 ENOG4108VEU Thiamine monophosphate synthase AOD60_04040 ENOG41080HI glycine oxidase AOD60_04055 ENOG4105D06 uba thif-type nad fad binding protein AOD60_04060 ENOG4105DWF phosphomethylpyrimidine kinase AOD60_04110 ENOG4108INS Transcriptional regulator AOD60_04125 ENOG4105C7N Xanthine uracil vitamin C permease AOD60_04155 ENOG4105C5Y PTS System AOD60_04215 ENOG4107Y03 Nitroreductase AOD60_04220 ENOG4105ED1 spovr family AOD60_04245 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase AOD60_04250 ENOG4105XTG Pfam:DUF156 AOD60_04255 ENOG4105VFE sira family AOD60_04260 ENOG4107TPS domain protein AOD60_04265 ENOG4105VFE sira family AOD60_04270 ENOG41085GJ domain protein AOD60_04280 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase AOD60_04285 ENOG41087NI Sulfite exporter TauE/SafE AOD60_04295 ENOG4108KGH TRANSCRIPTIONal AOD60_04320 ENOG4105EMD TRANSCRIPTIONal AOD60_04325 ENOG4105VCP PTS System AOD60_04330 ENOG4105VZJ PTS System AOD60_04350 ENOG41069ER domain protein AOD60_04355 ENOG4107RBB ABC transporter, permease AOD60_04360 ENOG4105C19 ABC transporter AOD60_04390 ENOG4105WEF catalase AOD60_04425 ENOG4107T5V SNARE associated Golgi AOD60_04460 ENOG4105CUB amino acid AOD60_04465 ENOG4107RWR Sodium hydrogen exchanger AOD60_04475 ENOG4106KNT transcriptional regulator AOD60_04510 ENOG4108PCN EamA-like transporter family AOD60_04515 ENOG4108YXU transcriptional regulator AsnC family AOD60_04525 ENOG4105KPY Small multidrug resistance protein AOD60_04530 ENOG4105KPY Small multidrug resistance protein AOD60_04555 ENOG4105NF4 modulator of drug activity AOD60_04560 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) AOD60_04565 ENOG4105E5W Transporter AOD60_04575 ENOG4107RKG DJ-1/PfpI family AOD60_04580 ENOG4105CH6 catalase AOD60_04590 ENOG4105D5Q Arginine ornithine antiporter AOD60_04595 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AOD60_04605 ENOG4105C26 Dehydrogenase AOD60_04615 ENOG4105BZ1 (ABC) transporter AOD60_04630 ENOG4105DRP amino acid AbC transporter AOD60_04635 ENOG4105CDA abc transporter atp-binding protein AOD60_04650 ENOG410839P AOD60_04685 ENOG4107FQX Alpha-acetolactate decarboxylase AOD60_04715 ENOG4105D4P Coproporphyrinogen iii oxidase AOD60_04730 ENOG4105CHH sulfate transporter AOD60_04770 ENOG4106AKK s-layer domain-containing protein AOD60_04780 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOD60_04785 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOD60_04800 ENOG4105CGU Enoyl-CoA hydratase AOD60_04820 ENOG4105DER m42 family AOD60_04840 ENOG4105CTU Proline racemase AOD60_04885 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOD60_04895 ENOG4108JQ7 (ABC) transporter AOD60_04925 ENOG4105CSH Transporter AOD60_04935 ENOG4108MRH transcriptional regulatory protein AOD60_04985 ENOG4105CDU Replicative dna helicase AOD60_05025 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_05075 ENOG4107P5I polyketide synthase AOD60_05080 ENOG4108IG5 Transcriptional regulator AOD60_05100 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AOD60_05120 ENOG4105CMT Dihydroxyacetone kinase AOD60_05135 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AOD60_05140 ENOG410847I Transcriptional regulator, BadM Rrf2 family AOD60_05165 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AOD60_05230 ENOG4105WN5 stage II sporulation protein AOD60_05240 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_05250 ENOG4108MJI response regulator AOD60_05255 ENOG4105BZU Histidine kinase AOD60_05260 ENOG4105BZU Histidine kinase AOD60_05285 ENOG4105K8R UPF0145 protein AOD60_05320 ENOG4107VRP DNA repair exonuclease AOD60_05325 ENOG4106D4I domain protein AOD60_05330 ENOG4105D7V transposase AOD60_05345 ENOG4108IND Tetr family transcriptional regulator AOD60_05350 ENOG4105EQ0 Major Facilitator superfamily AOD60_05370 ENOG4108MUZ hydrolase AOD60_05390 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator AOD60_05405 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AOD60_05420 ENOG4105EMN RNA polymerase sigma factor AOD60_05445 ENOG4105C57 major facilitator superfamily AOD60_05450 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_05460 ENOG4105EEM helicase AOD60_05465 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOD60_05495 ENOG4105K59 histidine triad (HIT) protein AOD60_05525 ENOG410905X membrane-flanked domain protein AOD60_05535 ENOG4105CKV Membrane AOD60_05575 ENOG410905X membrane-flanked domain protein AOD60_05580 ENOG4105CKV Membrane AOD60_05585 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation AOD60_05590 ENOG4105BZ4 penicillin-binding protein AOD60_05595 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AOD60_05605 ENOG4105C1Q protoporphyrinogen oxidase AOD60_05630 ENOG4105NA0 Transcriptional regulator AOD60_05645 ENOG4105ECB domain protein AOD60_05675 ENOG4106AXD AOD60_05680 ENOG4108RQ5 Beta-lactamase domain-containing protein AOD60_05685 ENOG4105DF9 Lipoate-protein, ligase AOD60_05695 ENOG4105CEY Amp-dependent synthetase and ligase AOD60_05725 ENOG4105CNA YD repeat protein AOD60_05760 ENOG4105ENX hydrolase AOD60_05770 ENOG4107RN3 metallophosphoesterase AOD60_05775 ENOG4107TVP HD domain protein AOD60_05785 ENOG4108AEY RNA polymerase sigma factor AOD60_05790 ENOG41086D8 Transcriptional regulator AOD60_05810 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_05835 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 AOD60_05840 ENOG4105C8Q Methyl-accepting chemotaxis AOD60_05860 ENOG4105ZU5 s-layer protein AOD60_05865 ENOG4107QP3 malate synthase g AOD60_05880 ENOG4105VEQ Cold shock protein AOD60_05895 ENOG4105XVF Competence transcription factor AOD60_05910 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination AOD60_05915 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation AOD60_05960 ENOG4105ERH Fumarylacetoacetate hydrolase AOD60_05985 ENOG4105CAQ asparagine synthetase AOD60_05990 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AOD60_05995 ENOG4105CH6 catalase AOD60_06000 ENOG4105BZU Histidine kinase AOD60_06025 ENOG4105QNR S1 RNA binding domain protein AOD60_06035 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOD60_06045 ENOG4107AYK membrAne AOD60_06050 ENOG41073B9 AOD60_06060 ENOG4108KP7 hydrolase AOD60_06075 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AOD60_06100 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOD60_06105 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AOD60_06120 ENOG4105C31 Tryptophanyl-tRNA synthetase AOD60_06135 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOD60_06140 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOD60_06150 ENOG4108JQ7 (ABC) transporter AOD60_06155 ENOG4105UQX Mate efflux family protein AOD60_06180 ENOG4108ZCF integral membrane protein AOD60_06190 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOD60_06200 ENOG4105DPN Oligoendopeptidase f AOD60_06215 ENOG4108Z18 K06886 hemoglobin AOD60_06220 ENOG4105MIX Adenylate cyclase AOD60_06235 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AOD60_06240 ENOG4105EMS pseudouridine synthase AOD60_06260 ENOG4105K64 Glycosyl transferase, family 2 AOD60_06280 ENOG4107TVC Glycosyl transferase, family 2 AOD60_06300 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AOD60_06305 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AOD60_06315 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AOD60_06365 ENOG4108WVJ 2'-5' rna ligase AOD60_06390 ENOG4105CK7 Sodium proline symporter AOD60_06400 ENOG4105CRQ synthase (Component I) AOD60_06405 ENOG4105DDQ anthranilate synthase AOD60_06495 ENOG4105C7S Dehydrogenase AOD60_06505 ENOG4105VZ8 Transcriptional regulator AOD60_06565 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) AOD60_06575 ENOG4105DZ1 carboxypeptidase AOD60_06580 ENOG4105VFR signal peptidase AOD60_06615 ENOG4105C26 Dehydrogenase AOD60_06620 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOD60_06625 ENOG4105F38 ABC transporter, permease AOD60_06630 ENOG4105D38 putrescine abc transporter AOD60_06635 ENOG4107RUE extracellular solute-binding protein family 1 AOD60_06645 ENOG4105EYF MMPL domain protein AOD60_06655 ENOG4108YBP pseudouridine synthase AOD60_06665 ENOG4105K4I Scp-like extracellular AOD60_06670 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AOD60_06675 ENOG4105CQB FAD linked oxidase domain protein AOD60_06690 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_06695 ENOG4105BZU Histidine kinase AOD60_06700 ENOG4105JXH GntR family transcriptional regulator AOD60_06720 ENOG4106A3R peptidase AOD60_06730 ENOG4108QTI )-transporter AOD60_06735 ENOG4107TS3 membrane protein, TerC AOD60_06740 ENOG4105CZN Potassium uptake protein AOD60_06745 ENOG410681C small acid-soluble spore protein AOD60_06750 ENOG4108Z7G MaoC domain protein dehydratase AOD60_06770 ENOG4105CHR reductase AOD60_06780 ENOG4105MWK D-amino acid dehydrogenase, small subunit AOD60_06800 ENOG4105C4Y ABC transporter AOD60_06815 ENOG4107RCV ABC transporter, permease AOD60_06820 ENOG4108KAZ Involved in phosphonate degradation (By similarity) AOD60_06835 ENOG4105E98 transcriptional regulator DeoR family AOD60_06860 ENOG4105PXI polysaccharide deacetylase AOD60_06870 ENOG4105BZU Histidine kinase AOD60_06875 ENOG41090MY MarR family Transcriptional regulator AOD60_06885 ENOG4106DF1 AOD60_06895 ENOG4105BZU Histidine kinase AOD60_06905 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AOD60_06910 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AOD60_06955 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) AOD60_06975 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AOD60_06980 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family AOD60_06985 ENOG4105CZV ABC transporter AOD60_06995 ENOG4105CJ1 ABC, transporter AOD60_07035 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AOD60_07040 ENOG4105EA8 2-Nitropropane dioxygenase AOD60_07045 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD AOD60_07055 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOD60_07080 ENOG4105NQC Flavodoxin AOD60_07115 ENOG4107QMU Mate efflux family protein AOD60_07120 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOD60_07150 ENOG4105CZN Potassium uptake protein AOD60_07155 ENOG41063Y9 AOD60_07160 ENOG4105KBJ sporulation protein ytfj AOD60_07190 ENOG4105CM2 brancheD-chain amino acid aminotransferase AOD60_07195 ENOG4105C7K acetolactate synthase AOD60_07200 ENOG4108ZP8 Acetolactate synthase small subunit AOD60_07205 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AOD60_07215 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AOD60_07240 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AOD60_07275 ENOG4107RVV histidinol phosphate phosphatase, hisj family AOD60_07290 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AOD60_07295 ENOG4105E0M Sulfatase AOD60_07305 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AOD60_07325 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AOD60_07330 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AOD60_07340 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AOD60_07345 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein AOD60_07350 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein AOD60_07360 ENOG4105C8J )-transporter AOD60_07380 ENOG4105DFD Na H antiporter AOD60_07400 ENOG4105ENE Histidine kinase AOD60_07405 ENOG4105WH1 Two component transcriptional regulator luxr family AOD60_07425 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) AOD60_07450 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AOD60_07475 ENOG4105CJ3 phosphate transporter AOD60_07480 ENOG4107GRR phosphate transport regulator AOD60_07485 ENOG4105BZ4 penicillin-binding protein AOD60_07500 ENOG4105BZU Histidine kinase AOD60_07505 ENOG4105I3N Conserved Protein AOD60_07520 ENOG4105BZU Histidine kinase AOD60_07555 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOD60_07560 ENOG4105DZ1 carboxypeptidase AOD60_07565 ENOG4108JIC nucleoside recognition domain protein AOD60_07575 ENOG4105FE9 pseudouridine synthase AOD60_07585 ENOG4107TWT Cytochrome c biogenesis protein AOD60_07590 ENOG4105CRE cytochrome C AOD60_07595 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_07600 ENOG4105BZU Histidine kinase AOD60_07605 ENOG4108WBT adenosyltransferase AOD60_07620 ENOG4108SAX Membrane AOD60_07630 ENOG4105T7X AOD60_07635 ENOG4105C9U ATP-dependent DNA helicase RecQ AOD60_07640 ENOG4105I7S Abortive infection protein AOD60_07655 ENOG4107X2D transcriptional regulator, merr family AOD60_07660 ENOG4108S6Z Negative regulator of genetic competence AOD60_07685 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase AOD60_07690 ENOG4107RB3 L-asparaginase AOD60_07725 ENOG4105S2F AOD60_07730 ENOG41065D1 AOD60_07760 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) AOD60_07775 ENOG4105XXQ heptaprenyl diphosphate synthase component I AOD60_07785 ENOG4105EAH synthase AOD60_07805 ENOG4105CIH Imidazole acetol-phosphate transaminase AOD60_07810 ENOG41068YB TPR repeat-containing protein AOD60_07825 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) AOD60_07830 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) AOD60_07835 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit AOD60_07865 ENOG4108JYZ YitT family AOD60_07875 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase AOD60_07890 ENOG4105FJR Lmbe family AOD60_07895 ENOG4105CPK Glycosyl transferase (Group 1 AOD60_07935 ENOG4105DVT helicase AOD60_07940 ENOG4105YAC AOD60_07960 ENOG4105CSM endonuclease III AOD60_07970 ENOG4105BZ4 penicillin-binding protein AOD60_08020 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) AOD60_08030 ENOG4105DVT helicase AOD60_08035 ENOG4105CTD carboxy-peptidase AOD60_08050 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AOD60_08060 ENOG4105C2W permease AOD60_08065 ENOG4105DHF Membrane AOD60_08070 ENOG410890F Dynamin family AOD60_08080 ENOG4108W0I acetyltransferase AOD60_08090 ENOG4105KHC sulfurtransferase AOD60_08105 ENOG4106032 Glutathionylspermidine synthase AOD60_08165 ENOG4105CPK Glycosyl transferase (Group 1 AOD60_08180 ENOG4108SZE gCN5-related N-acetyltransferase AOD60_08200 ENOG41081VK Ribonuclease AOD60_08265 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOD60_08275 ENOG4107RWR Sodium hydrogen exchanger AOD60_08280 ENOG4105CN5 Metallo-Beta-Lactamase AOD60_08285 ENOG4108Z5V transcriptional regulator, merr family AOD60_08295 ENOG4105H67 Protein of unknown function (DUF421) AOD60_08300 ENOG41080C8 DUF218 domain AOD60_08355 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AOD60_08365 ENOG4107R0U MotA TolQ exbB proton channel AOD60_08370 ENOG4105ER2 Ompa motb domain protein AOD60_08375 ENOG4107YTP response regulator receiver protein AOD60_08385 ENOG4105DD5 Flagellar motor switch protein AOD60_08400 ENOG4105BZU Histidine kinase AOD60_08420 ENOG4105E1Q flagellar hook-associated protein AOD60_08425 ENOG4105DTJ flagellar hook-associated protein AOD60_08450 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AOD60_08455 ENOG4108ZC9 flagellar basal-body rod protein flgc AOD60_08460 ENOG41075Z6 flagellar hook-basal body complex protein fliE AOD60_08465 ENOG4107U2N Flagellar M-ring protein AOD60_08475 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AOD60_08510 ENOG4105BZE flagellar hook protein, FlgE AOD60_08535 ENOG4105K64 Glycosyl transferase, family 2 AOD60_08565 ENOG4107TVC Glycosyl transferase, family 2 AOD60_08590 ENOG4105I03 Flagellin AOD60_08595 ENOG4105E4C Lytic transglycosylase catalytic AOD60_08610 ENOG4105DD5 Flagellar motor switch protein AOD60_08620 ENOG4105CN7 Flagellar biosynthetic protein FliP AOD60_08625 ENOG4105VS8 Flagellar biosynthetic protein fliq AOD60_08635 ENOG4105D00 flagellar biosynthetic protein flhB AOD60_08640 ENOG4105D7B Flagellar biosynthesis protein flha AOD60_08650 ENOG4105KTQ flagellar basal-body rod protein AOD60_08655 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOD60_08680 ENOG4108RZE Tetr family transcriptional regulator AOD60_08700 ENOG4105KAC Antibiotic biosynthesis monooxygenase AOD60_08725 ENOG4105DUM transcriptional regulator, lysR family AOD60_08730 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOD60_08735 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOD60_08740 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component AOD60_08745 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AOD60_08780 ENOG4105CVJ phosphoglycerate mutase AOD60_08810 ENOG4105CAQ asparagine synthetase AOD60_08830 ENOG4105PGM cation diffusion facilitator family transporter AOD60_08840 ENOG4105DRR Transcriptional regulator, GntR family AOD60_08845 ENOG4108UZ3 Transporter AOD60_08850 ENOG4105CKI cobalamin synthesis protein AOD60_08855 ENOG4108PJD permease AOD60_08870 ENOG4105DFD Na H antiporter AOD60_08875 ENOG4105C9Q fumarate hydratase class II AOD60_08905 ENOG4105EC3 peptidase S51, dipeptidase E AOD60_08925 ENOG4107QIV Cytochrome c biogenesis protein AOD60_08960 ENOG4106BRA Membrane AOD60_08995 ENOG4105CJ1 ABC, transporter AOD60_09015 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) AOD60_09025 ENOG4108IJ0 Aspartate ammonia-lyase AOD60_09030 ENOG4105C6K Malic enzyme AOD60_09100 ENOG4105FVX AOD60_09140 ENOG4105CSR polyphosphate kinase 2 AOD60_09160 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AOD60_09175 ENOG4105EU0 Major facilitator Superfamily AOD60_09180 ENOG4105C6T cysteine synthase AOD60_09200 ENOG4105C8J )-transporter AOD60_09210 ENOG4105X5K response regulator receiver protein AOD60_09215 ENOG4105H67 Protein of unknown function (DUF421) AOD60_09230 ENOG4106KE4 Dehydrogenase AOD60_09245 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AOD60_09250 ENOG4105CHR reductase AOD60_09255 ENOG4105CM2 brancheD-chain amino acid aminotransferase AOD60_09260 ENOG4105C7K acetolactate synthase AOD60_09265 ENOG4108ZP8 Acetolactate synthase small subunit AOD60_09270 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AOD60_09280 ENOG4105C7B Threonine dehydratase AOD60_09305 ENOG4105C6X Major Facilitator AOD60_09310 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AOD60_09320 ENOG4105DY9 regulatoR AOD60_09325 ENOG4105CYC Transferase AOD60_09345 ENOG4105F6J Alpha beta hydrolase fold AOD60_09350 ENOG4108J59 Extracellular solute-binding protein, family 5 AOD60_09380 ENOG41068WN AOD60_09400 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AOD60_09405 ENOG4105C72 UPF0176 protein AOD60_09415 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AOD60_09450 ENOG4107RHR regulatoR AOD60_09460 ENOG4105D9N nucleoside AOD60_09465 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) AOD60_09500 ENOG4107RAQ aminopeptidase AOD60_09505 ENOG4107STQ Multicopper oxidase AOD60_09550 ENOG4108T5E Copper resistance protein AOD60_09555 ENOG4105KTB nuclear export factor GLE1 AOD60_09565 ENOG4107RT3 EamA-like transporter family AOD60_09570 ENOG4105GZI Transcriptional regulator AOD60_09575 ENOG4108Z40 Transcriptional regulator AOD60_09580 ENOG4107ZXU DSBA oxidoreductase AOD60_09585 ENOG4108TVJ Nitroreductase AOD60_09595 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AOD60_09600 ENOG4106F5Q Membrane AOD60_09605 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOD60_09615 ENOG4105CKI cobalamin synthesis protein AOD60_09635 ENOG4108Z7G MaoC domain protein dehydratase AOD60_09640 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOD60_09650 ENOG4105C0Z ABC transporter AOD60_09655 ENOG4108IV0 ABC, transporter AOD60_09660 ENOG4105C32 Amino acid ABC transporter (Permease) AOD60_09670 ENOG4105SKE transcriptional Regulator LysR family AOD60_09690 ENOG4105YGB Transcriptional regulator AOD60_09700 ENOG4105C4M (Ubiquinol oxidase) subunit I AOD60_09705 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AOD60_09710 ENOG4108JJ9 ABC, transporter AOD60_09715 ENOG4108JJ8 (ABC) transporter AOD60_09760 ENOG4105BZ1 (ABC) transporter AOD60_09765 ENOG4105BZ1 (ABC) transporter AOD60_09770 ENOG4105EFI regulatoR AOD60_09775 ENOG4105BZU Histidine kinase AOD60_09795 ENOG41075D4 Aminoglycoside 6-adenylyltransferase AOD60_09800 ENOG4108ZJ4 polysaccharide deacetylase AOD60_09820 ENOG4105D6E homoserine dehydrogenase AOD60_09845 ENOG4108KGH TRANSCRIPTIONal AOD60_09855 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_09860 ENOG4105BZU Histidine kinase AOD60_09865 ENOG4107VMI polysaccharide deacetylase AOD60_09875 ENOG4105KT7 mgtC SapB transporter AOD60_09880 ENOG4105VRR gCN5-related N-acetyltransferase AOD60_09890 ENOG4105DUU IucA IucC family protein AOD60_09895 ENOG4105CEY Amp-dependent synthetase and ligase AOD60_09910 ENOG4108WBH protein TIM barrel AOD60_09915 ENOG4105YWU small acid-soluble spore protein AOD60_09925 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AOD60_09975 ENOG4105KRN Transcriptional regulator, abrb family AOD60_09985 ENOG4105YVS arsR family transcriptional regulator AOD60_09990 ENOG4107SET aldo keto reductase AOD60_09995 ENOG4107XZQ multidrug resistance protein AOD60_10020 ENOG4105C8Q Methyl-accepting chemotaxis AOD60_10040 ENOG4108K88 Membrane AOD60_10045 ENOG4108WPJ Ferritin-like domain AOD60_10060 ENOG4105DEN Luciferase family AOD60_10080 ENOG4107QM2 Aldo Keto reductase AOD60_10085 ENOG4105CKI cobalamin synthesis protein AOD60_10150 ENOG4105DSE periplasmic solute binding protein AOD60_10160 ENOG4105K4T epimerase AOD60_10170 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AOD60_10195 ENOG4105CVJ phosphoglycerate mutase AOD60_10215 ENOG4107T5V SNARE associated Golgi AOD60_10230 ENOG4108PJD permease AOD60_10240 ENOG4108S4H thioesterase Superfamily protein AOD60_10245 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOD60_10265 ENOG4105SXS Protein of unknown function (DUF456) AOD60_10270 ENOG4105C37 (CBS) domain AOD60_10290 ENOG4108Z7R Chaperone CsaA AOD60_10310 ENOG4108ZRV stage ii sporulation protein p AOD60_10320 ENOG4108VXD carboxy-peptidase AOD60_10330 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AOD60_10355 ENOG4108X4Q Hydrolase AOD60_10365 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AOD60_10370 ENOG4107RBS Methyltransferase AOD60_10385 ENOG41087PP glycosyltransferase MGT family AOD60_10390 ENOG4108JYZ YitT family AOD60_10395 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AOD60_10420 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) AOD60_10470 ENOG4105KBJ sporulation protein ytfj AOD60_10495 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AOD60_10515 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) AOD60_10520 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_10530 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AOD60_10535 ENOG4105EMN RNA polymerase sigma factor AOD60_10560 ENOG4108V06 Glutathione peroxidase AOD60_10575 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOD60_10595 ENOG4108IUE nitrate reductase beta subunit AOD60_10600 ENOG4105R3A Nitrate reductase AOD60_10625 ENOG4107V6Q Cyclic nucleotide-binding domain AOD60_10630 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AOD60_10635 ENOG4105D06 uba thif-type nad fad binding protein AOD60_10640 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOD60_10645 ENOG4108ZAF Molybdopterin AOD60_10670 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein AOD60_10675 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein AOD60_10680 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AOD60_10685 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit AOD60_10690 ENOG4108IFG nitrite reductase, (NAD(P)H) AOD60_10695 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) AOD60_10730 ENOG4105MCT stage V sporulation protein S AOD60_10745 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AOD60_10765 ENOG4105C5H ABC transporter AOD60_10780 ENOG4108UUM single-stranded DNA-binding protein AOD60_10795 ENOG41061H0 Monooxygenase AOD60_10815 ENOG4107YX5 Pfam:DUF548 AOD60_10820 ENOG4105C75 arginyL-tRNA synthetase AOD60_10845 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AOD60_10860 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) AOD60_10865 ENOG4105C5S asparaginyl-tRNA synthetase AOD60_10885 ENOG4105EC2 ftsk spoIIIe AOD60_10980 ENOG4105BZW Glycerate kinase AOD60_10985 ENOG4107QPK )-transporter AOD60_10990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_10995 ENOG41062D9 Histidine kinase AOD60_11010 ENOG4105C8J )-transporter AOD60_11030 ENOG4107XGZ Hydrolase AOD60_11035 ENOG4105CY2 Citrate transporter AOD60_11040 ENOG4105C0A alcohol dehydrogenase AOD60_11055 ENOG4105KD7 acetyltransferase AOD60_11085 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 AOD60_11105 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) AOD60_11120 ENOG4107RVG penicillin-binding protein AOD60_11125 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AOD60_11130 ENOG4105E9Q Acyl-transferase AOD60_11135 ENOG4108UT2 hemolysin iii AOD60_11145 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AOD60_11155 ENOG4108RCR degv family AOD60_11160 ENOG4105E8R UPF0173 metal-dependent hydrolase AOD60_11165 ENOG4108KF3 Electron transport protein SCO1 SenC AOD60_11170 ENOG4107Y70 Heat shock protein AOD60_11175 ENOG4105CAQ asparagine synthetase AOD60_11195 ENOG4108MES Periplasmic binding protein AOD60_11200 ENOG4105F0I Aminotransferase AOD60_11235 ENOG4105D8X mechanosensitive ion channel AOD60_11240 ENOG4105BZU Histidine kinase AOD60_11245 ENOG4105WH1 Two component transcriptional regulator luxr family AOD60_11255 ENOG4106KNT transcriptional regulator AOD60_11290 ENOG4105CMG Carbohydrate kinase AOD60_11295 ENOG4105CMG Carbohydrate kinase AOD60_11325 ENOG4108IJ8 ABC transporter AOD60_11330 ENOG4105E90 ABC transporter AOD60_11365 ENOG4105C37 (CBS) domain AOD60_11390 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOD60_11405 ENOG4107S4Y M20 DapE family protein YgeY AOD60_11410 ENOG4108TSC N-acetyltransferase AOD60_11415 ENOG4108JUB Transcriptional regulator AOD60_11420 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AOD60_11460 ENOG4108N23 SpoOM-related protein AOD60_11465 ENOG410841Q phosphoesterase PA-phosphatase related protein AOD60_11475 ENOG4105SZ6 Thioredoxin AOD60_11490 ENOG4108IBT Inherit from COG: transposase AOD60_11590 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOD60_11630 ENOG4105BZ4 penicillin-binding protein AOD60_11640 ENOG4105CZM Major Facilitator AOD60_11645 ENOG4105W8X HesB YadR YfhF-family protein AOD60_11655 ENOG4105DXD 2-methylcitrate dehydratase AOD60_11660 ENOG4105CR4 methylisocitrate lyase AOD60_11665 ENOG4105C1G acyl-Coa dehydrogenase AOD60_11670 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AOD60_11680 ENOG4105N14 lysine exporter protein LysE YggA AOD60_11685 ENOG4105E39 Enoyl-CoA hydratase AOD60_11700 ENOG4107RFY SbcCD D subunit AOD60_11705 ENOG4105EYH Exonuclease AOD60_11735 ENOG4105FCD Major Facilitator AOD60_11740 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AOD60_11745 ENOG4105E4F Isochorismate synthase AOD60_11750 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AOD60_11755 ENOG4105WQI isochorismatase AOD60_11760 ENOG4105CEY Amp-dependent synthetase and ligase AOD60_11765 ENOG4105WQT MbtH domain protein AOD60_11770 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_11785 ENOG4105K70 DNA-binding protein AOD60_11805 ENOG4105BZG amino acid carrier protein AOD60_11830 ENOG4105FE9 pseudouridine synthase AOD60_11835 ENOG4105C22 threonyL-tRNA synthetase AOD60_11850 ENOG4107SKW Inherit from COG: Alpha beta hydrolase AOD60_11875 ENOG4108D32 Methyltransferase AOD60_11905 ENOG41081I9 integral membrane protein AOD60_11920 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AOD60_11930 ENOG4105EYF MMPL domain protein AOD60_11955 ENOG4105WCN acetyltransferase AOD60_11985 ENOG4105C1Q protoporphyrinogen oxidase AOD60_11995 ENOG41068WN AOD60_12005 ENOG4105VEQ Cold shock protein AOD60_12025 ENOG410667J hydrolase AOD60_12070 ENOG4107V2S Transcriptional regulator AOD60_12075 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AOD60_12090 ENOG4105DND Transcriptional regulator AOD60_12095 ENOG4108RPX mosc domain containing protein AOD60_12110 ENOG4105BZ1 (ABC) transporter AOD60_12115 ENOG4105BZ1 (ABC) transporter AOD60_12135 ENOG4108JCI Transcriptional regulator AOD60_12165 ENOG4108KPJ rna polymerase sigma factor AOD60_12190 ENOG4105F32 YngK protein AOD60_12215 ENOG4105RD7 BadF BadG BcrA BcrD AOD60_12225 ENOG4107STF Involved in phosphonate degradation (By similarity) AOD60_12245 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AOD60_12260 ENOG4105C1J atp-dependent rna helicase AOD60_12275 ENOG4108RZE Tetr family transcriptional regulator AOD60_12295 ENOG41088CC tellurite resistance protein tehB AOD60_12305 ENOG4108I0C methyltransferase AOD60_12310 ENOG4107RA9 decarboxylase AOD60_12315 ENOG41090HR transcriptional regulator AOD60_12355 ENOG4105CIN aminoacyl-histidine dipeptidase AOD60_12380 ENOG4107RF6 penicillin-binding protein AOD60_12395 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AOD60_12400 ENOG4105ETE Transcriptional regulator (LacI family AOD60_12405 ENOG4105IE8 Alpha-ketoglutarate permease AOD60_12410 ENOG4105CK5 oxidoreductase AOD60_12435 ENOG4105D2N Aldolase AOD60_12440 ENOG4105DH8 myo-inositol catabolism AOD60_12455 ENOG4105CGH 5'-nucleotidase AOD60_12465 ENOG4105CGH 5'-nucleotidase AOD60_12480 ENOG4105VZ8 Transcriptional regulator AOD60_12495 ENOG4108VXD carboxy-peptidase AOD60_12515 ENOG41067SE Tetr family transcriptional regulator AOD60_12520 ENOG4105C5H ABC transporter AOD60_12530 ENOG4105BZU Histidine kinase AOD60_12540 ENOG4106ANW SMI1_KNR4 AOD60_12545 ENOG4105CEP NADH dehydrogenase AOD60_12550 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AOD60_12565 ENOG4105CJ1 ABC, transporter AOD60_12575 ENOG4107Z3H Transcriptional regulator, TetR family AOD60_12590 ENOG4105C1G acyl-Coa dehydrogenase AOD60_12595 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AOD60_12600 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit AOD60_12605 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase AOD60_12610 ENOG4105E39 Enoyl-CoA hydratase AOD60_12615 ENOG4107QX3 carboxylase AOD60_12620 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AOD60_12630 ENOG4105WCN acetyltransferase AOD60_12635 ENOG4105DBI uridine monophosphokinase AOD60_12670 ENOG4105T9C HD domain AOD60_12680 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AOD60_12720 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOD60_12720 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOD60_12735 ENOG4105FQP Beta-lactamase AOD60_12745 ENOG4107Y80 Major Facilitator superfamily AOD60_12765 ENOG4105CUV Homoserine Kinase AOD60_12800 ENOG4105CPQ Dehydrogenase AOD60_12815 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOD60_12820 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOD60_12915 ENOG4105ETU transcriptional activator (TenA AOD60_13025 ENOG410667J hydrolase AOD60_13035 ENOG4105BZU Histidine kinase AOD60_13040 ENOG4107RF6 penicillin-binding protein AOD60_13060 ENOG4108JJB ABC transporter AOD60_13070 ENOG4108HGU Histidine kinase AOD60_13085 ENOG4105CB2 alcohol dehydrogenase AOD60_13090 ENOG4105CJN penicillin-binding protein AOD60_13100 ENOG4105FQP Beta-lactamase AOD60_13135 ENOG4108V4B ThiJ pfpI AOD60_13165 ENOG4107Y80 Major Facilitator superfamily AOD60_13180 ENOG4107VXM glycerophosphoryl diester phosphodiesterase AOD60_13200 ENOG4107Y9U Membrane AOD60_13235 ENOG4105FCD Major Facilitator AOD60_13250 ENOG4105E09 nadh pyrophosphatase AOD60_13255 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AOD60_13260 ENOG4108Z4K mutator MutT protein AOD60_13295 ENOG4108XI2 Domain of unknown function (DUF1963) AOD60_13325 ENOG4108NRW Phospholipase, patatin family AOD60_13330 ENOG4105KWG Pfam:DUF1696 AOD60_13365 ENOG4105PKS Excinuclease abc c subunit domain protein AOD60_13405 ENOG4107VFR oxidoreductase AOD60_13430 ENOG4105PAD Hydrolase AOD60_13450 ENOG4105DY8 decarboxylase AOD60_13465 ENOG4108IUM Glycogen debranching enzyme AOD60_13490 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AOD60_13500 ENOG4105FDR Membrane AOD60_13535 ENOG4108V3A UPF0421 protein AOD60_13555 ENOG4105MSI germination protein ypeb AOD60_13575 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) AOD60_13580 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) AOD60_13585 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) AOD60_13590 ENOG4107Z3H Transcriptional regulator, TetR family AOD60_13620 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family AOD60_13640 ENOG4105E98 transcriptional regulator DeoR family AOD60_13660 ENOG41062ES Transcriptional regulator AOD60_13680 ENOG4107QKR Dehydrogenase AOD60_13690 ENOG4107RUY (E1 component), alpha subunit AOD60_13700 ENOG4105E1F short-chain dehydrogenase reductase AOD60_13705 ENOG4105RHY Pfam:UPF0157 AOD60_13740 ENOG4107SQ8 Glycine betaine AOD60_13745 ENOG4108IJ7 Glycine betaine AOD60_13770 ENOG4105E66 phosphoriboisomerase A AOD60_13775 ENOG41082BV acetyltransferase AOD60_13780 ENOG4108M1A Chitin-binding protein AOD60_13825 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AOD60_13875 ENOG4105EEM helicase AOD60_13895 ENOG4105C9U ATP-dependent DNA helicase RecQ AOD60_13950 ENOG4108M1A Chitin-binding protein AOD60_13965 ENOG4105BZG amino acid carrier protein AOD60_13970 ENOG4105C26 Dehydrogenase AOD60_13975 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AOD60_13980 ENOG4105CTU Proline racemase AOD60_13985 ENOG4105CTU Proline racemase AOD60_13990 ENOG41080HI glycine oxidase AOD60_14030 ENOG4107T5V SNARE associated Golgi AOD60_14045 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD AOD60_14050 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AOD60_14065 ENOG4105DTQ mandelate racemase muconate lactonizing AOD60_14105 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) AOD60_14110 ENOG4105BZU Histidine kinase AOD60_14115 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_14155 ENOG4105EPR degv family AOD60_14195 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) AOD60_14200 ENOG4106K7D Major facilitator family transporter AOD60_14220 ENOG4107BMA Transglycosylase associated protein AOD60_14235 ENOG41089UC methyltransferase, type 11 AOD60_14270 ENOG4105CHM Aminotransferase AOD60_14305 ENOG4105DVE abc transporter atp-binding protein AOD60_14355 ENOG4105C02 permease AOD60_14370 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AOD60_14375 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AOD60_14380 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein AOD60_14405 ENOG4105E09 nadh pyrophosphatase AOD60_14425 ENOG4108AQF aminoglycoside N(3)-acetyltransferase AOD60_14475 ENOG4107VC0 DNA alkylation repair enzyme AOD60_14485 ENOG4107VMI polysaccharide deacetylase AOD60_14495 ENOG4108ZCF integral membrane protein AOD60_14500 ENOG4105E0M Sulfatase AOD60_14505 ENOG4105C5H ABC transporter AOD60_14515 ENOG4105EYF MMPL domain protein AOD60_14520 ENOG4105EYF MMPL domain protein AOD60_14525 ENOG4105EYF MMPL domain protein AOD60_14530 ENOG41082JN Transcriptional regulator AOD60_14550 ENOG4105CIH Imidazole acetol-phosphate transaminase AOD60_14555 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AOD60_14560 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AOD60_14595 ENOG41069ER domain protein AOD60_14605 ENOG4105EMN RNA polymerase sigma factor AOD60_14630 ENOG4105D4B ABC, transporter AOD60_14640 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AOD60_14650 ENOG4105DKT Transcriptional regulator AOD60_14665 ENOG41061GT Aldolase AOD60_14685 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) AOD60_14715 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AOD60_14720 ENOG4105II7 pyrroline-5-carboxylate reductase AOD60_14730 ENOG4107258 Transcriptional regulator AOD60_14740 ENOG4105E0Y RtcB Protein AOD60_14745 ENOG4105ECK Fatty Acid Desaturase AOD60_14750 ENOG4105G6Z alkaline phosphatase AOD60_14760 ENOG4105VMP Transcriptional regulator AOD60_14775 ENOG41090T1 Membrane AOD60_14785 ENOG4108WCX response regulator AOD60_14795 ENOG41068WN AOD60_14820 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOD60_14845 ENOG4105CKK Glycosyl transferase, family 2 AOD60_14870 ENOG4105CKK Glycosyl transferase, family 2 AOD60_14880 ENOG4105C8Y Acetylornithine aminotransferase AOD60_14920 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOD60_14930 ENOG4108TVJ Nitroreductase AOD60_14935 ENOG4105FS7 Transcriptional regulator AOD60_14970 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOD60_14980 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AOD60_15010 ENOG4108XET gCN5-related N-acetyltransferase AOD60_15090 ENOG410635A Membrane AOD60_15095 ENOG4105KNA -acetyltransferase AOD60_15100 ENOG4108IQI permease AOD60_15110 ENOG4105F1N DNA alkylation repair AOD60_15150 ENOG4107RF6 penicillin-binding protein AOD60_15160 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AOD60_15200 ENOG4105P4J Allophanate hydrolase, subunit 1 AOD60_15205 ENOG4107258 Transcriptional regulator AOD60_15215 ENOG4106N3A copper homeostasis protein cutc AOD60_15220 ENOG4108ZRV stage ii sporulation protein p AOD60_15225 ENOG4108ZHR arsR family transcriptional regulator AOD60_15235 ENOG4105FDT acyl-CoA dehydrogenase AOD60_15255 ENOG4105DWD nucleoside recognition domain protein AOD60_15285 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AOD60_15350 ENOG4105E2A Dehydrogenase AOD60_15365 ENOG4108IJ0 Aspartate ammonia-lyase AOD60_15370 ENOG4105HDK L-asparaginase AOD60_15375 ENOG4108IMY Transcriptional regulator AOD60_15385 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AOD60_15390 ENOG4105CUB amino acid AOD60_15400 ENOG4105II7 pyrroline-5-carboxylate reductase AOD60_15410 ENOG4105C6K Malic enzyme AOD60_15420 ENOG4108NHD germination protein AOD60_15425 ENOG4108NHD germination protein AOD60_15430 ENOG4108Q8B Spore germination protein AOD60_15450 ENOG4105CSV Glutaminase AOD60_15480 ENOG4105CGH 5'-nucleotidase AOD60_15485 ENOG4105CH6 catalase AOD60_15495 ENOG4105CHJ isochorismatase hydrolase AOD60_15560 ENOG4108606 TspO/MBR family AOD60_15565 ENOG4105CVP deoxyribo-dipyrimidine photolyase AOD60_15580 ENOG4108TWJ NADH dehydrogenase subunit 5 AOD60_15585 ENOG4105GPN Uncharacterized conserved protein (DUF2294) AOD60_15595 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AOD60_15600 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AOD60_15605 ENOG4105DSE periplasmic solute binding protein AOD60_15610 ENOG4105CC5 ABC transporter AOD60_15615 ENOG4105DIK (ABC) transporter AOD60_15645 ENOG4105D6J arsenicaL-resistance protein AOD60_15650 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_15655 ENOG41085FC arsR family transcriptional regulator AOD60_15670 ENOG4105F7F Chaperone AOD60_15680 ENOG4105CHR reductase AOD60_15685 ENOG4108YXU transcriptional regulator AsnC family AOD60_15760 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AOD60_15770 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_15780 ENOG4105IIP Membrane AOD60_15795 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_15800 ENOG41062D9 Histidine kinase AOD60_15830 ENOG4105K6H D-cysteine desulfhydrase AOD60_15855 ENOG4105VZ8 Transcriptional regulator AOD60_15870 ENOG4108NNI Beta-lactamase domain-containing protein AOD60_15875 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AOD60_15885 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOD60_15890 ENOG4105JQZ Methyltransferase AOD60_15905 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AOD60_15910 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) AOD60_15930 ENOG4105BZU Histidine kinase AOD60_15945 ENOG4108U05 Transcriptional regulator AOD60_15960 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) AOD60_15965 ENOG4105DJB Major Facilitator Superfamily AOD60_15970 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) AOD60_15975 ENOG4107QR9 Iron-sulfur cluster binding protein AOD60_15985 ENOG4106P55 Transcriptional regulator AOD60_15995 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AOD60_16030 ENOG4105TRI Hydrolase AOD60_16065 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AOD60_16095 ENOG4107QJQ Mate efflux family protein AOD60_16110 ENOG4105EQ0 Major Facilitator superfamily AOD60_16115 ENOG4108JGH Tetr family transcriptional regulator AOD60_16130 ENOG4105C44 Serine transporter AOD60_16135 ENOG4105EJQ L-serine dehydratase AOD60_16150 ENOG4108JPW Aminotransferase AOD60_16165 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AOD60_16175 ENOG4105DVH amino acid AOD60_16190 ENOG4108JQ1 Dehydrogenase AOD60_16210 ENOG4108AEY RNA polymerase sigma factor AOD60_16225 ENOG41082W1 Cupin 2, conserved barrel domain protein AOD60_16235 ENOG410874W AraC family transcriptional regulator AOD60_16250 ENOG4105HIR S-layer domain protein AOD60_16290 ENOG4108ISG Major Facilitator AOD60_16300 ENOG4107MII Sugar-specific transcriptional regulator TrmB AOD60_16305 ENOG4105CZM Major Facilitator AOD60_16325 ENOG4105DA5 (ABC) transporter AOD60_16330 ENOG41069JR AOD60_16340 ENOG4105RXJ AOD60_16345 ENOG4105KPY Small multidrug resistance protein AOD60_16350 ENOG4105KBX Transcriptional regulator, TetR family AOD60_16365 ENOG4105CRW Short chain fatty acid transporter AOD60_16375 ENOG4105DYS nad(p)h dehydrogenase (quinone) AOD60_16405 ENOG4108JJB ABC transporter AOD60_16410 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) AOD60_16435 ENOG4108K8S endonuclease I AOD60_16450 ENOG41067QW Transcriptional regulator AOD60_16460 ENOG4108Z66 YbaK ebsC protein AOD60_16465 ENOG4105CUT histidyl-tRNA synthetase AOD60_16480 ENOG4105KVH Transcriptional regulator AOD60_16485 ENOG4108RCM Nitroreductase AOD60_16505 ENOG4108PSK reductase AOD60_16515 ENOG4105CJ1 ABC, transporter AOD60_16575 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_16580 ENOG4105DKQ ROK family AOD60_16585 ENOG4106UW1 Major Facilitator superfamily AOD60_16590 ENOG4108UW5 maltose o-acetyltransferase AOD60_16605 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AOD60_16610 ENOG4105C31 Tryptophanyl-tRNA synthetase AOD60_16615 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AOD60_16640 ENOG4105DMQ Methyltransferase AOD60_16650 ENOG4105EV4 Multidrug resistance protein mdtH AOD60_16680 ENOG4105C37 (CBS) domain AOD60_16695 ENOG4105DDN Pentapeptide repeat-containing protein AOD60_16700 ENOG4105XDF Protein of unknown function (DUF1272) AOD60_16705 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) AOD60_16710 ENOG4105CMG Carbohydrate kinase AOD60_16715 ENOG4105C6Z Gluconate AOD60_16720 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AOD60_16735 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AOD60_16740 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AOD60_16745 ENOG4105CIS alcohol dehydrogenase AOD60_16750 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AOD60_16770 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AOD60_16775 ENOG4105D4Y metalloprotease AOD60_16795 ENOG4105CV8 reductase AOD60_16800 ENOG4105F27 Major Facilitator AOD60_16815 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) AOD60_16820 ENOG4105C44 Serine transporter AOD60_16855 ENOG4105KVH Transcriptional regulator AOD60_16860 ENOG4108TZY GntR Family Transcriptional Regulator AOD60_16870 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AOD60_16875 ENOG4105KVH Transcriptional regulator AOD60_16880 ENOG4105KVH Transcriptional regulator AOD60_16915 ENOG4105JAB phenazine biosynthesis protein, phzf family AOD60_16925 ENOG4105CHR reductase AOD60_16945 ENOG4105KVH Transcriptional regulator AOD60_17015 ENOG4105KAF membrAne AOD60_17040 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) AOD60_17055 ENOG4107YXZ hydrolase, family 25 AOD60_17080 ENOG4105ED2 Beta-lactamase AOD60_17090 ENOG4105H3G oxidoreductase AOD60_17165 ENOG4108TN2 lmbE family AOD60_17175 ENOG4107R3E Citrate transporter AOD60_17195 ENOG4108MES Periplasmic binding protein AOD60_17205 ENOG4105EHG Permease protein AOD60_17210 ENOG4105DQ5 transport system permease protein AOD60_17215 ENOG4105NX3 Membrane AOD60_17220 ENOG4107ZY0 Phenazine biosynthesis-like protein AOD60_17240 ENOG4107CUJ Protein of unknown function (DUF2690) AOD60_17250 ENOG4107V2S Transcriptional regulator AOD60_17270 ENOG4105C98 muts2 protein AOD60_17280 ENOG4105E5K Alpha-amylase AOD60_17285 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase AOD60_17290 ENOG4105DPN Oligoendopeptidase f AOD60_17295 ENOG4108A04 Beta-lactamase AOD60_17325 ENOG4107VXM glycerophosphoryl diester phosphodiesterase AOD60_17350 ENOG41082BM Transcriptional regulator, arsr family AOD60_17355 ENOG4105CIS alcohol dehydrogenase AOD60_17380 ENOG4105RHY Pfam:UPF0157 AOD60_17390 ENOG4105C09 Bile acid AOD60_17395 ENOG4105CQB FAD linked oxidase domain protein AOD60_17420 ENOG4108UT6 Transferase hexapeptide repeat containing protein AOD60_17430 ENOG4105K64 Glycosyl transferase, family 2 AOD60_17435 ENOG4105E39 Enoyl-CoA hydratase AOD60_17445 ENOG4105KT7 mgtC SapB transporter AOD60_17455 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_17460 ENOG41073R8 VanW family AOD60_17470 ENOG4108R1P AOD60_17490 ENOG4105VEQ Cold shock protein AOD60_17510 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AOD60_17530 ENOG410904N short-chain dehydrogenase reductase AOD60_17540 ENOG4106IQC argininosuccinate lyase AOD60_17555 ENOG4108IA2 Sodium pantothenate symporter AOD60_17565 ENOG4105C26 Dehydrogenase AOD60_17570 ENOG4105CHR reductase AOD60_17580 ENOG4105EWU Squalene--hopene cyclase AOD60_17590 ENOG4105FR1 rard protein AOD60_17595 ENOG410696E Membrane AOD60_17610 ENOG4105D1F ATP-binding protein AOD60_17620 ENOG4108ZAF Molybdopterin AOD60_17625 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOD60_17630 ENOG4105D06 uba thif-type nad fad binding protein AOD60_17635 ENOG4105TMB Formate nitrite transporter AOD60_17645 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AOD60_17650 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) AOD60_17660 ENOG4108JB9 formate dehydrogenase AOD60_17670 ENOG4105E1K spore germination protein AOD60_17730 ENOG4107QJT sodium dicarboxylate symporter AOD60_17735 ENOG4108KGH TRANSCRIPTIONal AOD60_17745 ENOG4105EMN RNA polymerase sigma factor AOD60_17770 ENOG4105CIG ABC transporter AOD60_17780 ENOG4105D9R oxidoreductase AOD60_17790 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AOD60_17800 ENOG4105K4P CoA-binding domain protein AOD60_17805 ENOG4105C0H protease AOD60_17810 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_17820 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AOD60_17825 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) AOD60_17830 ENOG4105W8X HesB YadR YfhF-family protein AOD60_17860 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AOD60_17865 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AOD60_17875 ENOG4108JJA ABC, transporter AOD60_17880 ENOG4108I0Z Aconitate hydratase AOD60_17910 ENOG4105E5W Transporter AOD60_17920 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOD60_17940 ENOG4107F3J Amp-dependent synthetase and ligase AOD60_17945 ENOG4107ZYJ bioY protein AOD60_17950 ENOG4105CEY Amp-dependent synthetase and ligase AOD60_17995 ENOG4107AYK membrAne AOD60_18005 ENOG4105BZU Histidine kinase AOD60_18010 ENOG4105FBA Phospholipase Carboxylesterase AOD60_18015 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase AOD60_18020 ENOG4105CK7 Sodium proline symporter AOD60_18025 ENOG4105CBC glutamate synthase AOD60_18030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AOD60_18035 ENOG4108VJ1 Transcriptional regulator (CarD family AOD60_18040 ENOG4108903 Formimidoylglutamase AOD60_18065 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) AOD60_18125 ENOG4107QIV Cytochrome c biogenesis protein AOD60_18135 ENOG4107RSM transcriptional regulator AOD60_18140 ENOG4105VAW lrga family AOD60_18145 ENOG41067MG lrgb family AOD60_18170 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AOD60_18185 ENOG4105BZ1 (ABC) transporter AOD60_18190 ENOG4105BZ1 (ABC) transporter AOD60_18210 ENOG4105D7V transposase AOD60_18230 ENOG4105D5T phosphonate abc transporter AOD60_18245 ENOG4105CGH 5'-nucleotidase AOD60_18255 ENOG4108SVB resolvase AOD60_18275 ENOG4105K7K Transcriptional regulator AOD60_18310 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase AOD60_18315 ENOG4105XSJ toxin secretion phage lysis holin AOD60_18525 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) AOD60_18630 ENOG4105C5F glutamine synthetase AOD60_18635 ENOG4105KV4 Transcriptional regulator AOD60_18640 ENOG4105CXI aluminum resistance protein AOD60_18650 ENOG4105EN6 Membrane AOD60_18655 ENOG4106F1P AAA ATPase, central domain protein AOD60_18685 ENOG41069ER domain protein AOD60_18690 ENOG4105DM4 PTS System AOD60_18695 ENOG4105DE4 1-phosphofructokinase AOD60_18700 ENOG4105E98 transcriptional regulator DeoR family AOD60_18710 ENOG4108SJC Membrane AOD60_18725 ENOG4105C85 amino acid AOD60_18740 ENOG4105TMB Formate nitrite transporter AOD60_18745 ENOG4105K70 DNA-binding protein AOD60_18750 ENOG4105C59 p-type ATPase AOD60_18755 ENOG410681U heavy metal transport detoxification protein AOD60_18760 ENOG4105VPX protein, conserved in bacteria AOD60_18770 ENOG4105NIV Esterase AOD60_18775 ENOG4105E0A ABC, transporter AOD60_18800 ENOG4105CGK Exodeoxyribonuclease III AOD60_18810 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AOD60_18815 ENOG4105D03 DNA-3-methyladenine glycosylase II AOD60_18845 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_18850 ENOG4105BZU Histidine kinase AOD60_18870 ENOG41067MG lrgb family AOD60_18885 ENOG4107TTQ Alpha beta hydrolase fold AOD60_18890 ENOG4107YEI lmbE family AOD60_18910 ENOG4105F0V Cell wall hydrolase AOD60_18915 ENOG4107R6R udp-galactopyranose mutase AOD60_18920 ENOG4105E0M Sulfatase AOD60_18925 ENOG410890F Dynamin family AOD60_18935 ENOG4107QHE Choloylglycine hydrolase AOD60_18960 ENOG4105DA5 (ABC) transporter AOD60_18985 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AOD60_18990 ENOG4105DQU oxidoreductase, subunit beta AOD60_18995 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein AOD60_19000 ENOG4108IGT Dipeptidase AOD60_19005 ENOG4105MCT stage V sporulation protein S AOD60_19010 ENOG4105D48 metallophosphoesterase AOD60_19035 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AOD60_19050 ENOG4105XZV Protein of unknown function (DUF3243) AOD60_19055 ENOG4108RKS Short-chain dehydrogenase reductase Sdr AOD60_19075 ENOG4105UIB (ABC) transporter AOD60_19080 ENOG4105UIB (ABC) transporter AOD60_19085 ENOG4108JQ9 ABC transporter AOD60_19090 ENOG4105DIH basic membrane AOD60_19095 ENOG4105FDP GntR family transcriptional regulator AOD60_19100 ENOG4107QZI cell division protein FtsK AOD60_19110 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit AOD60_19125 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AOD60_19135 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AOD60_19140 ENOG4108S0H Dipicolinic acid synthetase, b subunit AOD60_19145 ENOG4105E35 Dipicolinate synthase subunit A AOD60_19155 ENOG4105C1V Peptidase, M16 AOD60_19175 ENOG4105DTN riboflavin biosynthesis protein ribF AOD60_19180 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AOD60_19190 ENOG4105W7A Protein of unknown function (DUF503) AOD60_19200 ENOG4105VHM ribosomal protein AOD60_19205 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination AOD60_19210 ENOG4105CHV Transcription elongation factor NusA AOD60_19220 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AOD60_19230 ENOG4105DZP Membrane-associated zinc metalloprotease AOD60_19235 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AOD60_19240 ENOG4105KNE Phosphatidate cytidylyltransferase AOD60_19245 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AOD60_19285 ENOG4108HE4 integrase family AOD60_19295 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AOD60_19305 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AOD60_19320 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) AOD60_19345 ENOG4105VB6 UPF0109 protein AOD60_19365 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AOD60_19370 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) AOD60_19385 ENOG4105CHR reductase AOD60_19390 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AOD60_19405 ENOG4105CB5 ATP-dependent DNA helicase recG AOD60_19410 ENOG4105DP4 dak2 domain fusion protein ylov AOD60_19415 ENOG4108ZAA Alkaline-shock protein AOD60_19430 ENOG4105FJ0 thiamine AOD60_19435 ENOG4105DJV ribulose-phosphate 3-epimerase AOD60_19440 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AOD60_19445 ENOG4105D9P serine threonine protein kinase AOD60_19450 ENOG4108ZF3 Phosphatase AOD60_19460 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AOD60_19470 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AOD60_19475 ENOG4105C25 Primosomal protein n' AOD60_19480 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AOD60_19500 ENOG4105DSJ YicC domain protein AOD60_19510 ENOG4105F23 Fibronectin-binding protein AOD60_19515 ENOG4105DC7 peptidase M24 AOD60_19570 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AOD60_19595 ENOG4105C34 Pseudouridine synthase AOD60_19610 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AOD60_19620 ENOG4105DBK s4 domain protein AOD60_19625 ENOG41067XK integral membrane protein AOD60_19635 ENOG4105DFA alanine racemase domain protein AOD60_19640 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AOD60_19645 ENOG4105WR5 sporulation protein, YlmC YmxH family AOD60_19655 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_19665 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AOD60_19670 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AOD60_19675 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) AOD60_19680 ENOG4105D4A Cell wall formation (By similarity) AOD60_19685 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AOD60_19690 ENOG4105CNI cell division protein FtsW AOD60_19705 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOD60_19710 ENOG4105CJN penicillin-binding protein AOD60_19715 ENOG4105CJN penicillin-binding protein AOD60_19720 ENOG41068DC Essential cell division protein (By similarity) AOD60_19755 ENOG4105KNH Nucleic acid-binding protein AOD60_19805 ENOG4105XSJ toxin secretion phage lysis holin AOD60_19890 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AOD60_19900 ENOG4105CAR Terminase, large subunit AOD60_19990 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AOD60_20000 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_20055 ENOG4108IMY Transcriptional regulator AOD60_20080 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) AOD60_20090 ENOG41063PX domain protein AOD60_20095 ENOG4105D78 K07001 NTE family protein AOD60_20100 ENOG4105H20 Sporulation integral membrane protein YlbJ AOD60_20110 ENOG4106H78 methyltransferase AOD60_20130 ENOG4107TB6 phosphoglycerate mutase AOD60_20145 ENOG4106UY4 Inherit from COG: Scp-like extracellular AOD60_20195 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) AOD60_20200 ENOG4105CNI cell division protein FtsW AOD60_20215 ENOG4108IAB Phoh family AOD60_20235 ENOG4105QA2 AOD60_20240 ENOG4105CI3 gtp-binding protein typa AOD60_20250 ENOG4105ECY inositol monophosphatase AOD60_20270 ENOG4105CXN decarboxylase AOD60_20315 ENOG4105C7S Dehydrogenase AOD60_20320 ENOG4105CPP Dehydrogenase, E1 component AOD60_20335 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AOD60_20340 ENOG4108X4Q Hydrolase AOD60_20350 ENOG4105CN5 Metallo-Beta-Lactamase AOD60_20355 ENOG4107ZYR domain protein AOD60_20390 ENOG4108XRC Protein of unknown function (DUF458) AOD60_20400 ENOG4107IN1 Protein of unknown function (DUF1797) AOD60_20415 ENOG4105EPM Diguanylate phosphodiesterase AOD60_20420 ENOG4105K6S Short-chain dehydrogenase reductase Sdr AOD60_20435 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AOD60_20445 ENOG4105UIN AOD60_20510 ENOG4108HGU Histidine kinase AOD60_20520 ENOG4105CHM Aminotransferase AOD60_20525 ENOG4105FKQ transcriptional regulator AOD60_20530 ENOG4105EG2 ABC transporter, permease AOD60_20540 ENOG4107FKK extracellular solute-binding protein family 1 AOD60_20550 ENOG4105CG3 alpha amylase, catalytic region AOD60_20595 ENOG4105CHU acetyl-coa acetyltransferase AOD60_20635 ENOG4105K7K Transcriptional regulator AOD60_20640 ENOG4105DTD Dehydrogenase AOD60_20650 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) AOD60_20660 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AOD60_20685 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) AOD60_20705 ENOG4106TD9 Diguanylate cyclase AOD60_20725 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AOD60_20740 ENOG4105CID antiterminator AOD60_20750 ENOG4105FDP GntR family transcriptional regulator AOD60_20760 ENOG4105CE4 GlcNAc 6-P deacetylase AOD60_20805 ENOG4107ZE5 PPIases accelerate the folding of proteins AOD60_20810 ENOG4105PTM secreted protein AOD60_20815 ENOG4105J7I hydrolase AOD60_20825 ENOG4105G6R Stage v sporulation protein ae AOD60_20835 ENOG4105CZ3 stage V sporulation protein ad AOD60_20840 ENOG41090VF Stage v sporulation protein ac AOD60_20860 ENOG4105C8J )-transporter AOD60_20865 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_20875 ENOG41082AN stage II sporulation protein AOD60_20880 ENOG4105DZ1 carboxypeptidase AOD60_20885 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOD60_20890 ENOG4105DVE abc transporter atp-binding protein AOD60_20925 ENOG4105D7N magnesium and cobalt transport protein CorA AOD60_20950 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AOD60_20960 ENOG4105I3K Ferric uptake regulator, Fur family AOD60_20965 ENOG4105MZ9 stage II sporulation protein m AOD60_20985 ENOG4105CPC Aldo Keto reductase AOD60_20995 ENOG4105RHY Pfam:UPF0157 AOD60_21015 ENOG4107SKW Inherit from COG: Alpha beta hydrolase AOD60_21025 ENOG4105ETE Transcriptional regulator (LacI family AOD60_21030 ENOG4108YM7 Gcn5-related n-acetyltransferase AOD60_21050 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AOD60_21055 ENOG4108R6K riboflavin synthase, subunit alpha AOD60_21075 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AOD60_21080 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOD60_21085 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOD60_21090 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AOD60_21100 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOD60_21110 ENOG4105DFD Na H antiporter AOD60_21115 ENOG4105CGH 5'-nucleotidase AOD60_21155 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AOD60_21170 ENOG4108IXY short-chain dehydrogenase reductase AOD60_21175 ENOG41069FQ Metallo-beta-lactamase superfamily AOD60_21185 ENOG4105II7 pyrroline-5-carboxylate reductase AOD60_21190 ENOG4105EJQ L-serine dehydratase AOD60_21215 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AOD60_21225 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AOD60_21230 ENOG4105D9U N-acetyltransferase AOD60_21245 ENOG4108VZI ErfK ybiS ycfS ynhG family protein AOD60_21250 ENOG4108QEG Membrane AOD60_21255 ENOG4105CDA abc transporter atp-binding protein AOD60_21260 ENOG4105E5Q amino acid AbC transporter AOD60_21265 ENOG4108HW3 (ABC) transporter AOD60_21275 ENOG4105G7B Protein of unknown function (DUF2992) AOD60_21295 ENOG4105C7S Dehydrogenase AOD60_21300 ENOG4105CPP Dehydrogenase, E1 component AOD60_21320 ENOG4107RDP Dehydrogenase AOD60_21335 ENOG4108JUB Transcriptional regulator AOD60_21345 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AOD60_21360 ENOG4107QQR Sporulation AOD60_21370 ENOG4105S1Z Stage IV sporulation protein B AOD60_21375 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AOD60_21385 ENOG4105DX0 Hemolysin A AOD60_21395 ENOG4105CTB Polyprenyl synthetase AOD60_21420 ENOG4108ZSR alkaline shock protein AOD60_21425 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AOD60_21450 ENOG410644B Stage III sporulation protein af AOD60_21460 ENOG4105KQ4 Stage iii sporulation protein ad AOD60_21465 ENOG4108CQH stage III sporulation protein AC AOD60_21470 ENOG4105KR5 Stage iii sporulation protein AOD60_21475 ENOG4105CD2 stage iii sporulation protein aa AOD60_21500 ENOG4105DC7 peptidase M24 AOD60_21515 ENOG4105CBJ Metal-dependent enzyme AOD60_21525 ENOG4107YBY Hydrolase AOD60_21545 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) AOD60_21550 ENOG4105WZW rhodanese family AOD60_21570 ENOG41080TC multidrug resistance protein AOD60_21610 ENOG4105CJ1 ABC, transporter AOD60_21615 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOD60_21645 ENOG4105C0D helicase AOD60_21765 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AOD60_21770 ENOG4105C3R Methionine synthase AOD60_21785 ENOG4105C28 cystathionine AOD60_21790 ENOG4105C28 cystathionine AOD60_21815 ENOG4105C5X domain protein AOD60_21825 ENOG4105DKQ ROK family AOD60_21835 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AOD60_21850 ENOG4108UTW Plays a role in the regulation of phosphate uptake AOD60_21855 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AOD60_21860 ENOG4105E2Z phosphate ABC transporter (Permease AOD60_21865 ENOG4105C8U phosphate abc transporter AOD60_21870 ENOG4105PWN phosphate abc transporter AOD60_21875 ENOG4107RF6 penicillin-binding protein AOD60_21885 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOD60_21910 ENOG4105N80 Ferric uptake regulator, Fur family AOD60_21920 ENOG4105FDK ABC transporter AOD60_21925 ENOG4108JYZ YitT family AOD60_21930 ENOG41069ZM Protein of unknown function (DUF2624) AOD60_21955 ENOG4105EGD dinuclear metal center protein, YbgI family AOD60_21970 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_21975 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AOD60_22010 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AOD60_22015 ENOG4105KG3 cytidine deaminase AOD60_22020 ENOG4107YR5 Diacylglycerol kinase AOD60_22030 ENOG4105CTJ Metal Dependent Phosphohydrolase AOD60_22035 ENOG4105C9A Phoh family AOD60_22050 ENOG41068P3 sporulation protein YqfC AOD60_22055 ENOG4105KTH gatB Yqey AOD60_22065 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AOD60_22070 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AOD60_22090 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AOD60_22100 ENOG4105CSA Coproporphyrinogen iii oxidase AOD60_22105 ENOG4105KVH Transcriptional regulator AOD60_22130 ENOG4105TQK DNA polymerase iii, delta' subunit AOD60_22140 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AOD60_22145 ENOG4108UK2 deaminase AOD60_22150 ENOG4105KQC Competence protein AOD60_22160 ENOG4105DXX methyltransferase AOD60_22170 ENOG4108WF2 Metal Dependent Phosphohydrolase AOD60_22180 ENOG410812S Rna-binding protein AOD60_22190 ENOG4105CQW ribosome biogenesis GTPase YqeH AOD60_22195 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase AOD60_22210 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_22230 ENOG4108TVJ Nitroreductase AOD60_22245 ENOG4105G6Z alkaline phosphatase AOD60_22255 ENOG4108MUZ hydrolase AOD60_22290 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin AOD60_22295 ENOG4105MIR Phenylalanine 4-monooxygenase AOD60_22305 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_22310 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_22350 ENOG4105S6R Iron-hydroxamate transporter permease subunit AOD60_22355 ENOG4108V5C ABC transporter AOD60_22365 ENOG4108EKI Dehydrogenase AOD60_22370 ENOG4105C28 cystathionine AOD60_22400 ENOG4107XRG penicillin-binding protein AOD60_22415 ENOG4105CFP Peptidase U32 AOD60_22420 ENOG4105XYU peptidase (U32 family) AOD60_22425 ENOG4108VQJ O-methyltransferase AOD60_22430 ENOG4105HHA aminodeoxychorismate lyase AOD60_22450 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOD60_22460 ENOG4105C02 permease AOD60_22475 ENOG41060CR AOD60_22480 ENOG4105C7H Helicase, RecD TraA family AOD60_22490 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AOD60_22495 ENOG4105C3J Cysteine desulfurase AOD60_22505 ENOG4105D1H recombination factor protein RarA AOD60_22510 ENOG4108VCI transcription factor, rsfa family AOD60_22515 ENOG4105CUZ uba thif-type nad fad binding protein AOD60_22525 ENOG4105CUT histidyl-tRNA synthetase AOD60_22540 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AOD60_22550 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AOD60_22555 ENOG41076HS cation diffusion facilitator family transporter AOD60_22560 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AOD60_22570 ENOG4105CKP Polysaccharide Biosynthesis Protein AOD60_22575 ENOG4108QG2 Membrane AOD60_22585 ENOG4105VIE preprotein translocase, subunit YajC AOD60_22600 ENOG41061AI Protein of unknown function (DUF2905) AOD60_22615 ENOG4108HUF Transporter AOD60_22625 ENOG4108IPJ Membrane AOD60_22630 ENOG4108IPJ Membrane AOD60_22635 ENOG41082BM Transcriptional regulator, arsr family AOD60_22660 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AOD60_22665 ENOG4108IYU L-aspartate oxidase AOD60_22680 ENOG4108RPX mosc domain containing protein AOD60_22685 ENOG4105CQC Prephenate dehydratase AOD60_22705 ENOG4105EWM Histidine kinase AOD60_22720 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AOD60_22735 ENOG4105X36 (ribosomal) protein AOD60_22745 ENOG4105C03 ribonuclease AOD60_22760 ENOG4107QMS site-determining protein AOD60_22775 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AOD60_22780 ENOG4105DFF Rod shape-determining protein mreb AOD60_22800 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AOD60_22805 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AOD60_22815 ENOG41068KH stage VI sporulation protein D AOD60_22825 ENOG4105D52 delta-aminolevulinic acid dehydratase AOD60_22850 ENOG4105K56 Transcriptional regulator AOD60_22870 ENOG4108IUQ atp-dependent protease AOD60_22900 ENOG4108QCI YvbH-like oligomerisation region AOD60_22920 ENOG4105M59 Phosphodiesterase, mj0936 family AOD60_22925 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AOD60_22935 ENOG4108XJQ germination protein AOD60_22945 ENOG4108PCX Major Facilitator AOD60_22955 ENOG4105KBX Transcriptional regulator, TetR family AOD60_22970 ENOG4105PFC Transcriptional regulator AOD60_22985 ENOG4105DZC cytosine deaminase AOD60_22990 ENOG4105DZC cytosine deaminase AOD60_22995 ENOG4105DEF Extracellular solute-binding protein, family 5 AOD60_23000 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOD60_23015 ENOG4108JQ7 (ABC) transporter AOD60_23020 ENOG4108HRK Histidine kinase AOD60_23025 ENOG4105DY9 regulatoR AOD60_23040 ENOG41067S9 phage shock protein C, PspC AOD60_23045 ENOG4108JCI Transcriptional regulator AOD60_23055 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AOD60_23060 ENOG4108Z40 Transcriptional regulator AOD60_23065 ENOG4105RHA ABC transporter, permease AOD60_23070 ENOG4108IUX (ABC) transporter AOD60_23075 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family AOD60_23085 ENOG4105E14 MotA TolQ exbB proton channel AOD60_23090 ENOG4108VXD carboxy-peptidase AOD60_23100 ENOG4105E33 succinate dehydrogenase AOD60_23110 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit AOD60_23125 ENOG4105K63 Thioredoxin AOD60_23130 ENOG4105C10 Electron transfer flavoprotein AOD60_23135 ENOG4105BZJ Electron transfer flavoprotein AOD60_23140 ENOG41060WC Enoyl-CoA hydratase AOD60_23145 ENOG4107Z3H Transcriptional regulator, TetR family AOD60_23150 ENOG4105CEY Amp-dependent synthetase and ligase AOD60_23160 ENOG4105J76 Periplasmic binding protein AOD60_23165 ENOG4105S6R Iron-hydroxamate transporter permease subunit AOD60_23210 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_23225 ENOG4105DR4 Methyltransferase AOD60_23240 ENOG4105KFN sortase, SrtB family AOD60_23245 ENOG4105E0A ABC, transporter AOD60_23260 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) AOD60_23270 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) AOD60_23280 ENOG4105FE9 pseudouridine synthase AOD60_23295 ENOG4105DCG PHP domain protein AOD60_23330 ENOG4105C5S asparaginyl-tRNA synthetase AOD60_23335 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AOD60_23345 ENOG4108RWN rrna methyltransferase AOD60_23380 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOD60_23385 ENOG4105CW7 secretion protein, HlyD family AOD60_23390 ENOG4108JGH Tetr family transcriptional regulator AOD60_23395 ENOG4105CN9 Peptidase m42 family protein AOD60_23415 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AOD60_23420 ENOG4105C22 threonyL-tRNA synthetase AOD60_23425 ENOG4108TDW sporulation protein YtxC AOD60_23445 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AOD60_23450 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AOD60_23455 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AOD60_23465 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AOD60_23470 ENOG4105C2M dna polymerase I AOD60_23475 ENOG4105BZU Histidine kinase AOD60_23480 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_23500 ENOG4108HMX isocitrate dehydrogenase (NADP) AOD60_23505 ENOG4105BZN citrate synthase AOD60_23520 ENOG4108REF Sporulation integral membrane protein ytvi AOD60_23525 ENOG4105FS0 cytoplasmic membrane protein AOD60_23550 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family AOD60_23555 ENOG4105C6K Malic enzyme AOD60_23560 ENOG4105C0B DNA polymerase III (alpha subunit) AOD60_23565 ENOG4105VV2 AOD60_23575 ENOG4105SFS phosphoesterase RecJ domain protein AOD60_23610 ENOG4105DC7 peptidase M24 AOD60_23645 ENOG4105Z7P Acetyltransferase (GNAT) family AOD60_23650 ENOG41082W1 Cupin 2, conserved barrel domain protein AOD60_23660 ENOG4105VZ8 Transcriptional regulator AOD60_23680 ENOG4107YZX Universal stress protein AOD60_23720 ENOG4108JYZ YitT family AOD60_23740 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AOD60_23750 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AOD60_23755 ENOG4105KBJ sporulation protein ytfj AOD60_23770 ENOG4105EFZ amidohydrolase AOD60_23780 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AOD60_23805 ENOG4106KR7 LysR family Transcriptional regulator AOD60_23825 ENOG4105C28 cystathionine AOD60_23845 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AOD60_23855 ENOG4105EMN RNA polymerase sigma factor AOD60_23870 ENOG4105F1V Acetoin utilization protein AOD60_23875 ENOG4105W87 Cbs domain AOD60_23880 ENOG4105DGU Histone deacetylase AOD60_23890 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOD60_23900 ENOG4107SNB ankyrin repeat protein YahD AOD60_23905 ENOG4105EP9 oxidoreductase AOD60_23935 ENOG4105ETE Transcriptional regulator (LacI family AOD60_23960 ENOG4105C88 aminopeptidase AOD60_24005 ENOG4108VDD TRNA binding domain protein AOD60_24035 ENOG4105C8F Beta-lactamase domain protein AOD60_24050 ENOG4108V15 phosphotransferase enzyme family AOD60_24055 ENOG4108IUM Glycogen debranching enzyme AOD60_24070 ENOG4107QSE Dipeptidase AOD60_24075 ENOG4107QSE Dipeptidase AOD60_24080 ENOG4105YW5 deoR family transcriptional regulator AOD60_24095 ENOG4105CBX hi0933 family AOD60_24130 ENOG4108VJ1 Transcriptional regulator (CarD family AOD60_24135 ENOG4107EXU Short-chain dehydrogenase reductase Sdr AOD60_24140 ENOG4105CSC Glucose uptake protein AOD60_24155 ENOG4108ZAF Molybdopterin AOD60_24160 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein AOD60_24165 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOD60_24175 ENOG4105D06 uba thif-type nad fad binding protein AOD60_24200 ENOG41085GJ domain protein AOD60_24210 ENOG4105DWV Homoserine O-trans-acetylase AOD60_24220 ENOG4108B31 Spore germination protein AOD60_24255 ENOG410605W Major Facilitator AOD60_24260 ENOG4107S91 Sodium hydrogen exchanger AOD60_24265 ENOG4105NCW Trka-c domain protein AOD60_24280 ENOG4105C19 ABC transporter AOD60_24300 ENOG4105N5T Radical SAM Protein AOD60_24310 ENOG4105DA5 (ABC) transporter AOD60_24340 ENOG4105E8V Alpha Beta Hydrolase Fold protein AOD60_24345 ENOG4108Z0R Transferase AOD60_24350 ENOG4105YVM Phosphoesterase, PA-phosphatase related AOD60_24355 ENOG4105BZF Glycosyl transferase (Group 1 AOD60_24365 ENOG4108RIR Molybdenum cofactor biosynthesis protein AOD60_24420 ENOG4105EGD dinuclear metal center protein, YbgI family AOD60_24425 ENOG4105BZU Histidine kinase AOD60_24430 ENOG4105BZU Histidine kinase AOD60_24435 ENOG4107S9D Alpha beta hydrolase AOD60_24455 ENOG4105D2X ABC transporter substrate-binding protein AOD60_24465 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component AOD60_24520 ENOG4108V2W Carbonate dehydratase AOD60_24525 ENOG4105C4M (Ubiquinol oxidase) subunit I AOD60_24530 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AOD60_24575 ENOG41087YS Phage shock protein A AOD60_24610 ENOG4105BZU Histidine kinase AOD60_24615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_24640 ENOG4108UGV hypoxanthine phosphoribosyltransferase AOD60_24645 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) AOD60_24680 ENOG4107ZTW SNARE associated Golgi AOD60_24695 ENOG4105C19 ABC transporter AOD60_24700 ENOG41086D8 Transcriptional regulator AOD60_24750 ENOG4105C6Z Gluconate AOD60_24755 ENOG4105FDP GntR family transcriptional regulator AOD60_24775 ENOG41069H0 dihydroorotase EC 3.5.2.3 AOD60_24805 ENOG4105DTQ mandelate racemase muconate lactonizing AOD60_24815 ENOG4108IPT Naphthoate synthase AOD60_24820 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) AOD60_24825 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AOD60_24830 ENOG4105E4F Isochorismate synthase AOD60_24835 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AOD60_24845 ENOG4105VEQ Cold shock protein AOD60_24870 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AOD60_24880 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) AOD60_24890 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOD60_24985 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AOD60_25020 ENOG4105KT7 mgtC SapB transporter AOD60_25025 ENOG4107PBV potassium channel AOD60_25035 ENOG4107QYV phosphohexose isomerase AOD60_25045 ENOG4105WG9 Conserved Protein AOD60_25055 ENOG4105CHM Aminotransferase AOD60_25060 ENOG4108ZB6 transcriptional regulator AsnC family AOD60_25065 ENOG4105C5I Dehydrogenase AOD60_25070 ENOG4108MUZ hydrolase AOD60_25080 ENOG4105C87 Aminotransferase class I and II AOD60_25095 ENOG4105Y38 Kinase-associated protein B AOD60_25105 ENOG4107R3E Citrate transporter AOD60_25120 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) AOD60_25125 ENOG4105KA0 thioesterase Superfamily protein AOD60_25145 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AOD60_25165 ENOG41069ER domain protein AOD60_25180 ENOG4105CEP NADH dehydrogenase AOD60_25210 ENOG4105EWC Purine nucleoside phosphorylase AOD60_25230 ENOG4108YX9 iron--sulfur cluster insertion protein erpA AOD60_25255 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOD60_25260 ENOG4105C4B ABC transporter, permease AOD60_25265 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AOD60_25310 ENOG41083MR nifu domain-containing protein AOD60_25325 ENOG4108W5N phosphatidylglycerophosphatase a AOD60_25340 ENOG4105DYS nad(p)h dehydrogenase (quinone) AOD60_25345 ENOG4105D4U had-superfamily hydrolase, subfamily iia AOD60_25360 ENOG4105CBT Fructose-1,6-bisphosphatase AOD60_25380 ENOG4105MMD transcriptional regulator AOD60_25385 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AOD60_25390 ENOG4107TXC Transcriptional regulator AOD60_25395 ENOG41090T1 Membrane AOD60_25420 ENOG4105FAA peptidase M23 AOD60_25430 ENOG4105KZD Domain of unknown function (DUF1805) AOD60_25435 ENOG4107R8B 5'-nucleotidase AOD60_25460 ENOG4105DIW FeS assembly protein SUFB AOD60_25465 ENOG4108UNV SUF system FeS assembly protein, NifU family AOD60_25470 ENOG4105C9B Cysteine desulfurase AOD60_25475 ENOG4105JRK feS assembly protein SufD AOD60_25480 ENOG4105C3K feS assembly ATPase SufC AOD60_25485 ENOG4105D01 (LipO)protein AOD60_25490 ENOG4105D01 (LipO)protein AOD60_25495 ENOG4108UMI ABC transporter, permease AOD60_25530 ENOG41080E8 Transcriptional regulator, Spx MgsR family AOD60_25580 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOD60_25605 ENOG4108W8B Beta-lactamase domain protein AOD60_25610 ENOG4105C1G acyl-Coa dehydrogenase AOD60_25620 ENOG4105CHU acetyl-coa acetyltransferase AOD60_25635 ENOG4105DZ1 carboxypeptidase AOD60_25655 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer AOD60_25675 ENOG4108SUT Major Facilitator Superfamily AOD60_25680 ENOG4107R7I amino acid AOD60_25690 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AOD60_25700 ENOG4107AYK membrAne AOD60_25735 ENOG4107ZTW SNARE associated Golgi AOD60_25745 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AOD60_25750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_25755 ENOG4105BZU Histidine kinase AOD60_25765 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AOD60_25780 ENOG4105VG1 fes assembly suf system protein AOD60_25785 ENOG4105D4Y metalloprotease AOD60_25805 ENOG4107S91 Sodium hydrogen exchanger AOD60_25810 ENOG4105NCW Trka-c domain protein AOD60_25825 ENOG4108RMU ferritin dps family protein AOD60_25840 ENOG4108URH decarboxylase AOD60_25865 ENOG4105D9N nucleoside AOD60_25870 ENOG4105D9N nucleoside AOD60_25885 ENOG4108RYK Nad-dependent epimerase dehydratase AOD60_25900 ENOG4105CV8 reductase AOD60_25905 ENOG4105F27 Major Facilitator AOD60_25910 ENOG4105KVH Transcriptional regulator AOD60_25925 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AOD60_25930 ENOG4105D4A Cell wall formation (By similarity) AOD60_25940 ENOG4105C8Q Methyl-accepting chemotaxis AOD60_25950 ENOG4105WMR Protein CrcB homolog AOD60_25955 ENOG4105WMR Protein CrcB homolog AOD60_25970 ENOG4108MK9 spermidine N(1)-acetyltransferase AOD60_25975 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AOD60_25990 ENOG4108IPW abc transporter atp-binding protein AOD60_25995 ENOG4105CM4 permease protein AOD60_26020 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AOD60_26030 ENOG4105XZU Preprotein translocase, subunit SecG AOD60_26035 ENOG41067MG lrgb family AOD60_26135 ENOG4105EFC phage portal protein HK97 family AOD60_26160 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AOD60_26170 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AOD60_26175 ENOG4105CP7 Triose-phosphate isomerase AOD60_26200 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_26220 ENOG41090VF Stage v sporulation protein ac AOD60_26225 ENOG4105CZ3 stage V sporulation protein ad AOD60_26240 ENOG4105H67 Protein of unknown function (DUF421) AOD60_26245 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AOD60_26250 ENOG4105KRI phosphocarrier protein (HPr AOD60_26260 ENOG4105CHW UPF0052 protein AOD60_26270 ENOG4108Z4K mutator MutT protein AOD60_26280 ENOG4105C3M thioredoxin reductase AOD60_26290 ENOG4108S4C acetyltransferase AOD60_26310 ENOG41086DT Membrane protein of unknown function AOD60_26320 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOD60_26325 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AOD60_26330 ENOG4105D7V transposase AOD60_26345 ENOG4107TXC Transcriptional regulator AOD60_26370 ENOG4105HMI Membrane AOD60_26375 ENOG4105DUM transcriptional regulator, lysR family AOD60_26385 ENOG4108WS4 fmn reductase AOD60_26400 ENOG4105BZ1 (ABC) transporter AOD60_26410 ENOG4105CN1 protease AOD60_26415 ENOG4105CRP Part of the ABC transporter FtsEX involved in AOD60_26420 ENOG4105CAK Cell division ATP-binding protein ftsE AOD60_26435 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) AOD60_26440 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving AOD60_26445 ENOG4105MS2 ribosomal subunit Interface protein AOD60_26450 ENOG4105VEQ Cold shock protein AOD60_26455 ENOG41081UC Inherit from COG: Competence protein AOD60_26470 ENOG4105KVH Transcriptional regulator AOD60_26485 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AOD60_26490 ENOG4108KGH TRANSCRIPTIONal AOD60_26495 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AOD60_26500 ENOG4105C6Y Udp-glucose 6-dehydrogenase AOD60_26505 ENOG4105ESV Glycosyl transferase, family 4 AOD60_26515 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AOD60_26530 ENOG410901P UPF0249 protein AOD60_26535 ENOG4105F8D glycoside hydrolase family 4 AOD60_26540 ENOG4105VCP PTS System AOD60_26545 ENOG4105CK1 PTS System AOD60_26555 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) AOD60_26560 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AOD60_26565 ENOG4105VCP PTS System AOD60_26575 ENOG4105VZJ PTS System AOD60_26590 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase AOD60_26595 ENOG4105ECB domain protein AOD60_26600 ENOG4107RSM transcriptional regulator AOD60_26645 ENOG4105DAA L-lactate AOD60_26655 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) AOD60_26665 ENOG4105E0M Sulfatase AOD60_26700 ENOG4105C94 Transporter AOD60_26705 ENOG41069ER domain protein AOD60_26730 ENOG4105KBK Zinc finger, swim domain protein AOD60_26735 ENOG4105C0D helicase AOD60_26765 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOD60_26775 ENOG4107RBB ABC transporter, permease AOD60_26780 ENOG4105C19 ABC transporter AOD60_26800 ENOG4105CXY transporter AOD60_26815 ENOG4105BZU Histidine kinase AOD60_26820 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_26825 ENOG4105CMR udp-glucose 4-epimerase AOD60_26840 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AOD60_26845 ENOG4105EY8 ABC transporter AOD60_26900 ENOG4105MT0 Sporulation transcriptional regulator spoiiid AOD60_26915 ENOG4105FRN stage II sporulation protein AOD60_26930 ENOG4105DY9 regulatoR AOD60_26935 ENOG4108IUW ABC transporter AOD60_26955 ENOG4106778 Protein of unknown function (DUF1146) AOD60_26960 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AOD60_26965 ENOG4105C8S subunit m AOD60_26970 ENOG4105D65 subunit l AOD60_26995 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AOD60_27000 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AOD60_27010 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AOD60_27015 ENOG4105BZU Histidine kinase AOD60_27065 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) AOD60_27070 ENOG41062M3 atp synthase AOD60_27100 ENOG4108YZG isomerase AOD60_27115 ENOG4108VGI doxx family AOD60_27120 ENOG4107XC4 flavin reductase domain protein, FMN-binding AOD60_27135 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AOD60_27145 ENOG4108ZXQ stage ii sporulation protein r AOD60_27150 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AOD60_27155 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) AOD60_27170 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AOD60_27175 ENOG4105CBT Fructose-1,6-bisphosphatase AOD60_27180 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AOD60_27215 ENOG4105C1G acyl-Coa dehydrogenase AOD60_27220 ENOG4105C1G acyl-Coa dehydrogenase AOD60_27225 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AOD60_27235 ENOG4105DF6 Fe-S oxidoreductase AOD60_27250 ENOG4105BZU Histidine kinase AOD60_27270 ENOG4105BZU Histidine kinase AOD60_27275 ENOG4105KCT ABC transporter AOD60_27280 ENOG4108M15 ABC transporter AOD60_27285 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) AOD60_27305 ENOG4105IIU Aminopeptidase AOD60_27325 ENOG4105EMN RNA polymerase sigma factor AOD60_27335 ENOG410684U Domain of unknown function (DUF1934) AOD60_27360 ENOG4105CYW agmatinase AOD60_27370 ENOG4105DXB Major Facilitator superfamily AOD60_27375 ENOG4107SWG transcriptional regulator MERR family AOD60_27380 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AOD60_27385 ENOG4105BZ4 penicillin-binding protein AOD60_27390 ENOG4108XFG YwhD family AOD60_27395 ENOG4108Z4T Peptidase M50 AOD60_27400 ENOG41069HH 4-oxalocrotonate tautomerase AOD60_27405 ENOG4105DCI Phosphohydrolase AOD60_27410 ENOG4108MES Periplasmic binding protein AOD60_27415 ENOG4105E0A ABC, transporter AOD60_27420 ENOG4105EHG Permease protein AOD60_27425 ENOG4105DQ5 transport system permease protein AOD60_27430 ENOG4105DQ5 transport system permease protein AOD60_27440 ENOG4108VCI transcription factor, rsfa family AOD60_27455 ENOG4108IJ2 phosphate acetyltransferase AOD60_27470 ENOG4108VKI Cell wall hydrolase AOD60_27500 ENOG410667J hydrolase AOD60_27505 ENOG4105VCH membrane AOD60_27515 ENOG4108TU7 Inherit from COG: (ABC) transporter AOD60_27520 ENOG4105CJ1 ABC, transporter AOD60_27525 ENOG41090WU lipolytic protein G-D-S-L family AOD60_27540 ENOG4105D6E homoserine dehydrogenase AOD60_27565 ENOG4108Y4K DNA-binding transcriptional activator AOD60_27575 ENOG4105WH1 Two component transcriptional regulator luxr family AOD60_27585 ENOG4105DWF phosphomethylpyrimidine kinase AOD60_27590 ENOG4105BZU Histidine kinase AOD60_27595 ENOG4105VCD cytoplasmic protein AOD60_27600 ENOG4105D22 carbon starvation protein AOD60_27605 ENOG4105DY9 regulatoR AOD60_27610 ENOG41079KZ Major Facilitator Superfamily AOD60_27630 ENOG4105EN6 Membrane AOD60_27635 ENOG4106YBV Methyl-accepting chemotaxis AOD60_27645 ENOG4108S4H thioesterase Superfamily protein AOD60_27655 ENOG4105JEU Glycosyl transferase, family 2 AOD60_27660 ENOG4105C5H ABC transporter AOD60_27690 ENOG4105CKK Glycosyl transferase, family 2 AOD60_27695 ENOG41067SE Tetr family transcriptional regulator AOD60_27705 ENOG4105E0X reductase AOD60_27710 ENOG4106F5Q Membrane AOD60_27725 ENOG4105DY9 regulatoR AOD60_27730 ENOG4108HRK Histidine kinase AOD60_27735 ENOG4107RGD Major Facilitator superfamily AOD60_27750 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOD60_27760 ENOG4105IW1 AmiS UreI transporter AOD60_27770 ENOG4105CMR udp-glucose 4-epimerase AOD60_27775 ENOG4108UT2 hemolysin iii AOD60_27785 ENOG4105C1J atp-dependent rna helicase AOD60_27800 ENOG4105DPN Oligoendopeptidase f AOD60_27820 ENOG4105C0H protease AOD60_27825 ENOG4105Q2H domain protein AOD60_27840 ENOG4105BZU Histidine kinase AOD60_27845 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOD60_27875 ENOG4105CDU Replicative dna helicase AOD60_27885 ENOG4105BZR domain protein AOD60_27890 ENOG4108XMW Membrane AOD60_27900 ENOG4108UUM single-stranded DNA-binding protein AOD60_27910 ENOG4105C3G gtp-binding protein AOD60_27915 ENOG4105VDK protein, conserved in bacteria AOD60_27920 ENOG4105D8X mechanosensitive ion channel AOD60_27925 ENOG4108ZDA Sporulation protein YyaC AOD60_27930 ENOG4105FA0 parb-like partition protein AOD60_27935 ENOG4107QJE Chromosome Partitioning Protein AOD60_27955 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AOD60_27965 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins