locus-tag class description AOQ81_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AOQ81_00015 ENOG410848D S4 domain protein YaaA AOQ81_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AOQ81_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AOQ81_00100 ENOG4105ZMH deoxynucleoside kinase AOQ81_00110 ENOG4105GTG Isochorismatase AOQ81_00120 ENOG4108Z6B deaminase AOQ81_00125 ENOG4105C6E dna polymerase iii AOQ81_00145 ENOG41067KS pro-sigma K processing AOQ81_00180 ENOG4105CXN decarboxylase AOQ81_00190 ENOG4105FA2 dna polymerase iii AOQ81_00195 ENOG4105MA4 psp1 domain protein AOQ81_00205 ENOG41060K3 Methyltransferase AOQ81_00215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AOQ81_00220 ENOG4105KRN Transcriptional regulator, abrb family AOQ81_00230 ENOG4105F8V Hydrolase, tatD family AOQ81_00235 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) AOQ81_00245 ENOG4105XFA sporulation peptidase YabG AOQ81_00250 ENOG4105W42 Veg protein AOQ81_00265 ENOG4105DFT pur operon repressor AOQ81_00270 ENOG4105KME endoribonuclease L-psp AOQ81_00285 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AOQ81_00290 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AOQ81_00300 ENOG4108JA2 transcriptioN-repair coupling factor AOQ81_00305 ENOG4108M14 stage v sporulation protein t AOQ81_00315 ENOG4108IY2 MazG family AOQ81_00320 ENOG41082I2 s4 domain protein AOQ81_00325 ENOG4105VYY sporulation protein yabp AOQ81_00340 ENOG41060GV RNA binding s1 domain protein AOQ81_00360 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AOQ81_00365 ENOG4108UGV hypoxanthine phosphoribosyltransferase AOQ81_00370 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AOQ81_00385 ENOG4105C6T cysteine synthase AOQ81_00390 ENOG4105CRQ synthase (Component I) AOQ81_00395 ENOG4105DDQ anthranilate synthase AOQ81_00400 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 AOQ81_00405 ENOG4105EEI dihydropteroate synthase AOQ81_00410 ENOG4105KRF dihydroneopterin aldolase AOQ81_00415 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AOQ81_00425 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AOQ81_00455 ENOG4108Z0C Uvrb UvrC protein AOQ81_00470 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AOQ81_00480 ENOG4105CTP PilT protein domain protein AOQ81_00500 ENOG4105D7W serine acetyltransferase AOQ81_00515 ENOG4105C2N RNA methyltransferase TrmH family group 3 AOQ81_00520 ENOG4105M0M Tetracycline resistance protein AOQ81_00525 ENOG4105QIV RNA polymerase AOQ81_00540 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AOQ81_00565 ENOG4107Y49 methyltransferase AOQ81_00575 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AOQ81_00580 ENOG4105XPM ribosomal protein AOQ81_00685 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AOQ81_00710 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AOQ81_00720 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AOQ81_00730 ENOG41067V7 50S ribosomal protein L36 AOQ81_00760 ENOG4108JJB ABC transporter AOQ81_00765 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) AOQ81_00770 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AOQ81_00795 ENOG4105D1F ATP-binding protein AOQ81_00810 ENOG4108NMV polysaccharide deacetylase AOQ81_00895 ENOG4105C8B TIGR00159 family AOQ81_00900 ENOG4107U5W ybbr family AOQ81_00915 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AOQ81_00920 ENOG4108VQT Alpha beta hydrolase fold protein AOQ81_00940 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AOQ81_00945 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein AOQ81_00980 ENOG4108PSK reductase AOQ81_00985 ENOG4108UMI ABC transporter, permease AOQ81_00990 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_00995 ENOG4105D01 (LipO)protein AOQ81_01000 ENOG4105EE1 crotonyl-CoA reductase AOQ81_01010 ENOG4105IQ5 FAD linked oxidase domain protein AOQ81_01025 ENOG4105C2C drug resistance transporter, Bcr CflA AOQ81_01040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOQ81_01045 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOQ81_01050 ENOG4105C3U ABC transporter AOQ81_01055 ENOG4108JQ7 (ABC) transporter AOQ81_01085 ENOG4108J59 Extracellular solute-binding protein, family 5 AOQ81_01090 ENOG4108J59 Extracellular solute-binding protein, family 5 AOQ81_01100 ENOG4105II7 pyrroline-5-carboxylate reductase AOQ81_01110 ENOG4107XDY Nicotinamide Mononucleotide Transporter AOQ81_01120 ENOG4105E0C molybdate abc transporter AOQ81_01125 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOQ81_01130 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOQ81_01135 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family AOQ81_01150 ENOG4105EGI Transcriptional regulator AOQ81_01165 ENOG4105F6E Acyl-transferase AOQ81_01185 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) AOQ81_01200 ENOG4108RE7 deoxyribonuclease AOQ81_01205 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) AOQ81_01230 ENOG4105C5H ABC transporter AOQ81_01245 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein AOQ81_01255 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOQ81_01260 ENOG4105C3U ABC transporter AOQ81_01265 ENOG4108JQ7 (ABC) transporter AOQ81_01290 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase AOQ81_01295 ENOG4105ERH Fumarylacetoacetate hydrolase AOQ81_01305 ENOG4108SC4 )-transporter AOQ81_01310 ENOG4105CPF Cell wall formation (By similarity) AOQ81_01315 ENOG4105CPF Cell wall formation (By similarity) AOQ81_01320 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) AOQ81_01335 ENOG4107ZXI Rhomboid family AOQ81_01345 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein AOQ81_01350 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AOQ81_01360 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) AOQ81_01460 ENOG4105K8N protein family UPF0079, ATPase AOQ81_01465 ENOG41072GX Peptidase M22 Glycoprotease AOQ81_01470 ENOG410801F ribosomal-protein-alanine acetyltransferase AOQ81_01475 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AOQ81_01480 ENOG4105C5H ABC transporter AOQ81_01495 ENOG4108TYN CAAX amino terminal protease family protein AOQ81_01515 ENOG4105C7N Xanthine uracil vitamin C permease AOQ81_01525 ENOG4105BZU Histidine kinase AOQ81_01555 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOQ81_01595 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOQ81_01615 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_01635 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AOQ81_01640 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AOQ81_01645 ENOG4105C83 adenylosuccinate lyase AOQ81_01655 ENOG4105VR9 phosphoribosylformylglycinamidine synthase AOQ81_01680 ENOG4108V3E phosphoribosylglycinamide formyltransferase AOQ81_01690 ENOG4105C12 Phosphoribosylglycinamide synthetase AOQ81_01715 ENOG4105C4R Atp-dependent dna helicase AOQ81_01745 ENOG4108W2Y isochorismatase AOQ81_01750 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_01755 ENOG4108UMI ABC transporter, permease AOQ81_01760 ENOG4105D01 (LipO)protein AOQ81_01780 ENOG410834F Transcriptional regulator AOQ81_01805 ENOG4105CBD Diacylglycerol kinase AOQ81_01810 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AOQ81_01815 ENOG4108JPW Aminotransferase AOQ81_01825 ENOG4105C26 Dehydrogenase AOQ81_01830 ENOG4105KPY Small multidrug resistance protein AOQ81_01850 ENOG4105D9N nucleoside AOQ81_01855 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AOQ81_01870 ENOG4108W15 Protein of unknown function (DUF1456) AOQ81_01885 ENOG4105DTQ mandelate racemase muconate lactonizing AOQ81_01895 ENOG4105DFD Na H antiporter AOQ81_01915 ENOG4105D3R alkyl hydroperoxide reductase AOQ81_01920 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) AOQ81_01930 ENOG4107W7X Aldolase AOQ81_01935 ENOG4105EHG Permease protein AOQ81_01940 ENOG4105DQ5 transport system permease protein AOQ81_01945 ENOG4108V5C ABC transporter AOQ81_01970 ENOG4106UIA AOQ81_01975 ENOG4106UIA AOQ81_02000 ENOG4105BZU Histidine kinase AOQ81_02020 ENOG410756H nucleotidyltransferase AOQ81_02025 ENOG4105D2S major facilitator superfamily AOQ81_02040 ENOG4105E5Q amino acid AbC transporter AOQ81_02045 ENOG4105EAB amino acid AbC transporter AOQ81_02060 ENOG4105C8Q Methyl-accepting chemotaxis AOQ81_02065 ENOG4105C8Q Methyl-accepting chemotaxis AOQ81_02075 ENOG4105CI1 PTS System AOQ81_02105 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AOQ81_02120 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AOQ81_02135 ENOG4105C5H ABC transporter AOQ81_02160 ENOG41062JF Transcriptional regulator AOQ81_02180 ENOG4105DEU major facilitator superfamily AOQ81_02195 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) AOQ81_02210 ENOG4108N0M stress protein AOQ81_02215 ENOG4106FN3 tellurium resistance protein AOQ81_02220 ENOG4106FN3 tellurium resistance protein AOQ81_02225 ENOG4107TS3 membrane protein, TerC AOQ81_02230 ENOG4108TTB tellurium resistance protein AOQ81_02250 ENOG4105KJF protein tyrosine phosphatase AOQ81_02260 ENOG4107U9T Pfam:Ribonuclease_BN AOQ81_02265 ENOG4105C59 p-type ATPase AOQ81_02270 ENOG4108IPJ Membrane AOQ81_02290 ENOG4107ZTW SNARE associated Golgi AOQ81_02305 ENOG410606W general stress protein AOQ81_02310 ENOG4105UPD Calcium Proton AOQ81_02350 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AOQ81_02355 ENOG4105VTR Integrase AOQ81_02360 ENOG4108IMY Transcriptional regulator AOQ81_02635 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AOQ81_02645 ENOG4108JUB Transcriptional regulator AOQ81_02655 ENOG4108IQI permease AOQ81_02690 ENOG4105CSV Glutaminase AOQ81_02700 ENOG4108A04 Beta-lactamase AOQ81_02715 ENOG4105CKK Glycosyl transferase, family 2 AOQ81_02725 ENOG4107QQG Dehydrogenase AOQ81_02730 ENOG4105C3I Nad-dependent epimerase dehydratase AOQ81_02750 ENOG4105F1A Pyruvate formate-lyase AOQ81_02770 ENOG4105CI2 imidazolone-5-propionate hydrolase AOQ81_02775 ENOG4105ECP epimerase AOQ81_02805 ENOG41067AE Membrane-bound metal-dependent hydrolase AOQ81_02810 ENOG4105CEN a g-specific adenine glycosylase AOQ81_02815 ENOG4106BXE AOQ81_02835 ENOG4105BZ1 (ABC) transporter AOQ81_02840 ENOG4107NBY Membrane AOQ81_02845 ENOG4105CBC glutamate synthase AOQ81_02855 ENOG4108IUW ABC transporter AOQ81_02875 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AOQ81_02880 ENOG4105G5W regulator Fur family AOQ81_02995 ENOG4108JQC penicillin-binding protein 1A AOQ81_03000 ENOG4107ZQN disulfide bond AOQ81_03010 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AOQ81_03020 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AOQ81_03025 ENOG4105BZU Histidine kinase AOQ81_03035 ENOG4105CYN Serine protein kinase AOQ81_03060 ENOG4105C94 Transporter AOQ81_03075 ENOG4105DZ6 Band 7 protein AOQ81_03085 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AOQ81_03095 ENOG4105D4T Citrate transporter AOQ81_03115 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator AOQ81_03120 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_03125 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AOQ81_03130 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component AOQ81_03135 ENOG4105BZ7 extracellular solute-binding protein family 1 AOQ81_03140 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AOQ81_03145 ENOG4108STX response regulator AOQ81_03150 ENOG4105US7 Histidine kinase AOQ81_03175 ENOG4108MRH transcriptional regulatory protein AOQ81_03185 ENOG4105C6K Malic enzyme AOQ81_03195 ENOG4108UZ3 Transporter AOQ81_03200 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AOQ81_03210 ENOG4105BZU Histidine kinase AOQ81_03215 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_03225 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) AOQ81_03230 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AOQ81_03235 ENOG4108JB9 formate dehydrogenase AOQ81_03255 ENOG4105CUB amino acid AOQ81_03265 ENOG4105C59 p-type ATPase AOQ81_03270 ENOG4105DAP Nicotinate phosphoribosyltransferase AOQ81_03300 ENOG41073R8 VanW family AOQ81_03305 ENOG4108KGH TRANSCRIPTIONal AOQ81_03310 ENOG4105D9N nucleoside AOQ81_03315 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AOQ81_03320 ENOG4105C37 (CBS) domain AOQ81_03325 ENOG4108IJ0 Aspartate ammonia-lyase AOQ81_03330 ENOG4105DAA L-lactate AOQ81_03345 ENOG4105DUX Transporter AOQ81_03350 ENOG4108MES Periplasmic binding protein AOQ81_03355 ENOG4105DQ5 transport system permease protein AOQ81_03360 ENOG4108IHU transport system permease protein AOQ81_03365 ENOG4105E0A ABC, transporter AOQ81_03370 ENOG4105DMQ Methyltransferase AOQ81_03390 ENOG4107T89 von Willebrand factor, type A AOQ81_03395 ENOG4105GMT ATPase associated with various cellular activities aaa_5 AOQ81_03400 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOQ81_03415 ENOG4105BZU Histidine kinase AOQ81_03420 ENOG4105D5Q Arginine ornithine antiporter AOQ81_03425 ENOG4107414 GntR family transcriptional regulator AOQ81_03430 ENOG4105C5Y PTS System AOQ81_03435 ENOG4105CG3 alpha amylase, catalytic region AOQ81_03450 ENOG4105E1K spore germination protein AOQ81_03460 ENOG4105CRN Aminoglycoside phosphotransferase AOQ81_03465 ENOG4105BZG amino acid carrier protein AOQ81_03470 ENOG4105CDA abc transporter atp-binding protein AOQ81_03475 ENOG4105CT1 (ABC) transporter AOQ81_03480 ENOG4105EAD ABC transporter AOQ81_03485 ENOG4105DRP amino acid AbC transporter AOQ81_03490 ENOG4108IQI permease AOQ81_03515 ENOG4105D29 Helix-turn-helix type 11 domain protein AOQ81_03520 ENOG4105NAE bifunctional deaminase-reductase domain protein AOQ81_03525 ENOG4105BZU Histidine kinase AOQ81_03540 ENOG4105CHH sulfate transporter AOQ81_03545 ENOG41068KF Universal stress protein AOQ81_03555 ENOG4105DEF Extracellular solute-binding protein, family 5 AOQ81_03565 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOQ81_03570 ENOG4108JQ7 (ABC) transporter AOQ81_03575 ENOG4105C3U ABC transporter AOQ81_03580 ENOG4105CXY transporter AOQ81_03585 ENOG41067TZ transcriptional regulator, MarR family AOQ81_03590 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_03595 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_03600 ENOG4105ETE Transcriptional regulator (LacI family AOQ81_03605 ENOG4108RVA ribokinase AOQ81_03615 ENOG4105C2J ABC transporter AOQ81_03620 ENOG4105CNN ABC, transporter AOQ81_03625 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AOQ81_03630 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AOQ81_03690 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOQ81_03695 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer AOQ81_03700 ENOG41069ER domain protein AOQ81_03705 ENOG4105VZ8 Transcriptional regulator AOQ81_03710 ENOG4107D63 AOQ81_03720 ENOG4105DUX Transporter AOQ81_03740 ENOG4105C85 amino acid AOQ81_03745 ENOG4105C7N Xanthine uracil vitamin C permease AOQ81_03785 ENOG4105BZ9 Cytochrome C oxidase, subunit I AOQ81_03790 ENOG4105E2S oxidase) subunit II AOQ81_03795 ENOG4108IQI permease AOQ81_03810 ENOG4106CAD Protein of unknown function (DUF3311) AOQ81_03815 ENOG4105E1V na solute symporter AOQ81_03830 ENOG4108NHD germination protein AOQ81_03840 ENOG4105CE1 Ferrous iron transport protein b AOQ81_03845 ENOG4105CE1 Ferrous iron transport protein b AOQ81_03850 ENOG4105CE1 Ferrous iron transport protein b AOQ81_03855 ENOG4105CVA phosphate AOQ81_03860 ENOG4105C8U phosphate abc transporter AOQ81_03865 ENOG4105E2Z phosphate ABC transporter (Permease AOQ81_03990 ENOG41080XQ Signal transduction protein with cbs domains AOQ81_04015 ENOG4105ETU transcriptional activator (TenA AOQ81_04025 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AOQ81_04035 ENOG4108VEU Thiamine monophosphate synthase AOQ81_04040 ENOG41080HI glycine oxidase AOQ81_04055 ENOG4105D06 uba thif-type nad fad binding protein AOQ81_04060 ENOG4105DWF phosphomethylpyrimidine kinase AOQ81_04105 ENOG4108INS Transcriptional regulator AOQ81_04120 ENOG4105C7N Xanthine uracil vitamin C permease AOQ81_04150 ENOG4105C5Y PTS System AOQ81_04210 ENOG4107Y03 Nitroreductase AOQ81_04215 ENOG4105ED1 spovr family AOQ81_04240 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase AOQ81_04245 ENOG4105XTG Pfam:DUF156 AOQ81_04250 ENOG4105VFE sira family AOQ81_04255 ENOG4107TPS domain protein AOQ81_04260 ENOG4105VFE sira family AOQ81_04265 ENOG41085GJ domain protein AOQ81_04275 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase AOQ81_04280 ENOG41087NI Sulfite exporter TauE/SafE AOQ81_04290 ENOG4108KGH TRANSCRIPTIONal AOQ81_04315 ENOG4105EMD TRANSCRIPTIONal AOQ81_04320 ENOG4105VCP PTS System AOQ81_04325 ENOG4105VZJ PTS System AOQ81_04345 ENOG41069ER domain protein AOQ81_04350 ENOG4107RBB ABC transporter, permease AOQ81_04355 ENOG4105C19 ABC transporter AOQ81_04385 ENOG4105WEF catalase AOQ81_04420 ENOG4107T5V SNARE associated Golgi AOQ81_04455 ENOG4105CUB amino acid AOQ81_04460 ENOG4107RWR Sodium hydrogen exchanger AOQ81_04470 ENOG4106KNT transcriptional regulator AOQ81_04505 ENOG4108PCN EamA-like transporter family AOQ81_04510 ENOG4108YXU transcriptional regulator AsnC family AOQ81_04520 ENOG4105KPY Small multidrug resistance protein AOQ81_04525 ENOG4105KPY Small multidrug resistance protein AOQ81_04550 ENOG4105NF4 modulator of drug activity AOQ81_04555 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) AOQ81_04560 ENOG4105E5W Transporter AOQ81_04570 ENOG4107RKG DJ-1/PfpI family AOQ81_04575 ENOG4105CH6 catalase AOQ81_04585 ENOG4105D5Q Arginine ornithine antiporter AOQ81_04590 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AOQ81_04600 ENOG4105C26 Dehydrogenase AOQ81_04610 ENOG4105BZ1 (ABC) transporter AOQ81_04625 ENOG4105DRP amino acid AbC transporter AOQ81_04630 ENOG4105CDA abc transporter atp-binding protein AOQ81_04645 ENOG410839P AOQ81_04680 ENOG4107FQX Alpha-acetolactate decarboxylase AOQ81_04710 ENOG4105D4P Coproporphyrinogen iii oxidase AOQ81_04725 ENOG4105CHH sulfate transporter AOQ81_04765 ENOG4106AKK s-layer domain-containing protein AOQ81_04775 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOQ81_04780 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOQ81_04795 ENOG4105CGU Enoyl-CoA hydratase AOQ81_04815 ENOG4105DER m42 family AOQ81_04835 ENOG4105CTU Proline racemase AOQ81_04880 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOQ81_04890 ENOG4108JQ7 (ABC) transporter AOQ81_04920 ENOG4105CSH Transporter AOQ81_04930 ENOG4108MRH transcriptional regulatory protein AOQ81_04980 ENOG4105CDU Replicative dna helicase AOQ81_05020 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_05070 ENOG4107P5I polyketide synthase AOQ81_05075 ENOG4108IG5 Transcriptional regulator AOQ81_05095 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AOQ81_05115 ENOG4105CMT Dihydroxyacetone kinase AOQ81_05130 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AOQ81_05135 ENOG410847I Transcriptional regulator, BadM Rrf2 family AOQ81_05160 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AOQ81_05225 ENOG4105WN5 stage II sporulation protein AOQ81_05235 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_05245 ENOG4108MJI response regulator AOQ81_05250 ENOG4105BZU Histidine kinase AOQ81_05255 ENOG4105BZU Histidine kinase AOQ81_05280 ENOG4105K8R UPF0145 protein AOQ81_05315 ENOG4107VRP DNA repair exonuclease AOQ81_05320 ENOG4106D4I domain protein AOQ81_05325 ENOG4105D7V transposase AOQ81_05340 ENOG4108IND Tetr family transcriptional regulator AOQ81_05345 ENOG4105EQ0 Major Facilitator superfamily AOQ81_05365 ENOG4108MUZ hydrolase AOQ81_05385 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator AOQ81_05400 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AOQ81_05415 ENOG4105EMN RNA polymerase sigma factor AOQ81_05440 ENOG4105C57 major facilitator superfamily AOQ81_05445 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_05455 ENOG4105EEM helicase AOQ81_05460 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOQ81_05490 ENOG4105K59 histidine triad (HIT) protein AOQ81_05520 ENOG410905X membrane-flanked domain protein AOQ81_05530 ENOG4105CKV Membrane AOQ81_05570 ENOG410905X membrane-flanked domain protein AOQ81_05575 ENOG4105CKV Membrane AOQ81_05580 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation AOQ81_05585 ENOG4105BZ4 penicillin-binding protein AOQ81_05590 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AOQ81_05600 ENOG4105C1Q protoporphyrinogen oxidase AOQ81_05625 ENOG4105NA0 Transcriptional regulator AOQ81_05640 ENOG4105ECB domain protein AOQ81_05670 ENOG4106AXD AOQ81_05675 ENOG4108RQ5 Beta-lactamase domain-containing protein AOQ81_05680 ENOG4105DF9 Lipoate-protein, ligase AOQ81_05690 ENOG4105CEY Amp-dependent synthetase and ligase AOQ81_05720 ENOG4105CNA YD repeat protein AOQ81_05755 ENOG4105ENX hydrolase AOQ81_05765 ENOG4107RN3 metallophosphoesterase AOQ81_05770 ENOG4107TVP HD domain protein AOQ81_05780 ENOG4108AEY RNA polymerase sigma factor AOQ81_05785 ENOG41086D8 Transcriptional regulator AOQ81_05805 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_05830 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 AOQ81_05835 ENOG4105C8Q Methyl-accepting chemotaxis AOQ81_05855 ENOG4105ZU5 s-layer protein AOQ81_05860 ENOG4107QP3 malate synthase g AOQ81_05875 ENOG4105VEQ Cold shock protein AOQ81_05890 ENOG4105XVF Competence transcription factor AOQ81_05905 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination AOQ81_05910 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation AOQ81_05955 ENOG4105ERH Fumarylacetoacetate hydrolase AOQ81_05980 ENOG4105CAQ asparagine synthetase AOQ81_05985 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AOQ81_05990 ENOG4105CH6 catalase AOQ81_05995 ENOG4105BZU Histidine kinase AOQ81_06020 ENOG4105QNR S1 RNA binding domain protein AOQ81_06030 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOQ81_06040 ENOG4107AYK membrAne AOQ81_06045 ENOG41073B9 AOQ81_06055 ENOG4108KP7 hydrolase AOQ81_06070 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AOQ81_06095 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOQ81_06100 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AOQ81_06115 ENOG4105C31 Tryptophanyl-tRNA synthetase AOQ81_06130 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AOQ81_06135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOQ81_06145 ENOG4108JQ7 (ABC) transporter AOQ81_06150 ENOG4105UQX Mate efflux family protein AOQ81_06175 ENOG4108ZCF integral membrane protein AOQ81_06185 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOQ81_06195 ENOG4105DPN Oligoendopeptidase f AOQ81_06210 ENOG4108Z18 K06886 hemoglobin AOQ81_06215 ENOG4105MIX Adenylate cyclase AOQ81_06230 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AOQ81_06235 ENOG4105EMS pseudouridine synthase AOQ81_06255 ENOG4105K64 Glycosyl transferase, family 2 AOQ81_06275 ENOG4107TVC Glycosyl transferase, family 2 AOQ81_06295 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AOQ81_06300 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AOQ81_06310 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AOQ81_06360 ENOG4108WVJ 2'-5' rna ligase AOQ81_06385 ENOG4105CK7 Sodium proline symporter AOQ81_06395 ENOG4105CRQ synthase (Component I) AOQ81_06400 ENOG4105DDQ anthranilate synthase AOQ81_06490 ENOG4105C7S Dehydrogenase AOQ81_06500 ENOG4105VZ8 Transcriptional regulator AOQ81_06560 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) AOQ81_06570 ENOG4105DZ1 carboxypeptidase AOQ81_06575 ENOG4105VFR signal peptidase AOQ81_06610 ENOG4105C26 Dehydrogenase AOQ81_06615 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_06620 ENOG4105F38 ABC transporter, permease AOQ81_06625 ENOG4105D38 putrescine abc transporter AOQ81_06630 ENOG4107RUE extracellular solute-binding protein family 1 AOQ81_06640 ENOG4105EYF MMPL domain protein AOQ81_06650 ENOG4108YBP pseudouridine synthase AOQ81_06660 ENOG4105K4I Scp-like extracellular AOQ81_06665 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AOQ81_06670 ENOG4105CQB FAD linked oxidase domain protein AOQ81_06685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_06690 ENOG4105BZU Histidine kinase AOQ81_06695 ENOG4105JXH GntR family transcriptional regulator AOQ81_06715 ENOG4106A3R peptidase AOQ81_06725 ENOG4108QTI )-transporter AOQ81_06730 ENOG4107TS3 membrane protein, TerC AOQ81_06735 ENOG4105CZN Potassium uptake protein AOQ81_06740 ENOG410681C small acid-soluble spore protein AOQ81_06745 ENOG4108Z7G MaoC domain protein dehydratase AOQ81_06765 ENOG4105CHR reductase AOQ81_06775 ENOG4105MWK D-amino acid dehydrogenase, small subunit AOQ81_06795 ENOG4105C4Y ABC transporter AOQ81_06810 ENOG4107RCV ABC transporter, permease AOQ81_06815 ENOG4108KAZ Involved in phosphonate degradation (By similarity) AOQ81_06830 ENOG4105E98 transcriptional regulator DeoR family AOQ81_06855 ENOG4105PXI polysaccharide deacetylase AOQ81_06865 ENOG4105BZU Histidine kinase AOQ81_06870 ENOG41090MY MarR family Transcriptional regulator AOQ81_06880 ENOG4106DF1 AOQ81_06890 ENOG4105BZU Histidine kinase AOQ81_06900 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AOQ81_06905 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AOQ81_06950 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) AOQ81_06970 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AOQ81_06975 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family AOQ81_06980 ENOG4105CZV ABC transporter AOQ81_06990 ENOG4105CJ1 ABC, transporter AOQ81_07030 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AOQ81_07035 ENOG4105EA8 2-Nitropropane dioxygenase AOQ81_07040 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD AOQ81_07050 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AOQ81_07075 ENOG4105NQC Flavodoxin AOQ81_07110 ENOG4107QMU Mate efflux family protein AOQ81_07115 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AOQ81_07145 ENOG4105CZN Potassium uptake protein AOQ81_07150 ENOG41063Y9 AOQ81_07155 ENOG4105KBJ sporulation protein ytfj AOQ81_07185 ENOG4105CM2 brancheD-chain amino acid aminotransferase AOQ81_07190 ENOG4105C7K acetolactate synthase AOQ81_07195 ENOG4108ZP8 Acetolactate synthase small subunit AOQ81_07200 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AOQ81_07210 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AOQ81_07235 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AOQ81_07270 ENOG4107RVV histidinol phosphate phosphatase, hisj family AOQ81_07285 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AOQ81_07290 ENOG4105E0M Sulfatase AOQ81_07300 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AOQ81_07320 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AOQ81_07325 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AOQ81_07335 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AOQ81_07340 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein AOQ81_07345 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein AOQ81_07355 ENOG4105C8J )-transporter AOQ81_07375 ENOG4105DFD Na H antiporter AOQ81_07395 ENOG4105ENE Histidine kinase AOQ81_07400 ENOG4105WH1 Two component transcriptional regulator luxr family AOQ81_07420 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) AOQ81_07445 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AOQ81_07470 ENOG4105CJ3 phosphate transporter AOQ81_07475 ENOG4107GRR phosphate transport regulator AOQ81_07480 ENOG4105BZ4 penicillin-binding protein AOQ81_07495 ENOG4105BZU Histidine kinase AOQ81_07500 ENOG4105I3N Conserved Protein AOQ81_07515 ENOG4105BZU Histidine kinase AOQ81_07550 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOQ81_07555 ENOG4105DZ1 carboxypeptidase AOQ81_07560 ENOG4108JIC nucleoside recognition domain protein AOQ81_07570 ENOG4105FE9 pseudouridine synthase AOQ81_07580 ENOG4107TWT Cytochrome c biogenesis protein AOQ81_07585 ENOG4105CRE cytochrome C AOQ81_07590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_07595 ENOG4105BZU Histidine kinase AOQ81_07600 ENOG4108WBT adenosyltransferase AOQ81_07615 ENOG4108SAX Membrane AOQ81_07625 ENOG4105T7X AOQ81_07630 ENOG4105C9U ATP-dependent DNA helicase RecQ AOQ81_07635 ENOG4105I7S Abortive infection protein AOQ81_07650 ENOG4107X2D transcriptional regulator, merr family AOQ81_07655 ENOG4108S6Z Negative regulator of genetic competence AOQ81_07680 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase AOQ81_07685 ENOG4107RB3 L-asparaginase AOQ81_07720 ENOG4105S2F AOQ81_07725 ENOG41065D1 AOQ81_07755 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) AOQ81_07770 ENOG4105XXQ heptaprenyl diphosphate synthase component I AOQ81_07780 ENOG4105EAH synthase AOQ81_07800 ENOG4105CIH Imidazole acetol-phosphate transaminase AOQ81_07805 ENOG41068YB TPR repeat-containing protein AOQ81_07820 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) AOQ81_07825 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) AOQ81_07830 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit AOQ81_07860 ENOG4108JYZ YitT family AOQ81_07865 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase AOQ81_07880 ENOG4105FJR Lmbe family AOQ81_07885 ENOG4105CPK Glycosyl transferase (Group 1 AOQ81_07925 ENOG4105DVT helicase AOQ81_07930 ENOG4105YAC AOQ81_07950 ENOG4105CSM endonuclease III AOQ81_07960 ENOG4105BZ4 penicillin-binding protein AOQ81_08010 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) AOQ81_08020 ENOG4105DVT helicase AOQ81_08025 ENOG4105CTD carboxy-peptidase AOQ81_08040 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AOQ81_08050 ENOG4105C2W permease AOQ81_08055 ENOG4105DHF Membrane AOQ81_08060 ENOG410890F Dynamin family AOQ81_08070 ENOG4108W0I acetyltransferase AOQ81_08080 ENOG4105KHC sulfurtransferase AOQ81_08095 ENOG4106032 Glutathionylspermidine synthase AOQ81_08155 ENOG4105CPK Glycosyl transferase (Group 1 AOQ81_08170 ENOG4108SZE gCN5-related N-acetyltransferase AOQ81_08190 ENOG41081VK Ribonuclease AOQ81_08255 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOQ81_08265 ENOG4107RWR Sodium hydrogen exchanger AOQ81_08270 ENOG4105CN5 Metallo-Beta-Lactamase AOQ81_08275 ENOG4108Z5V transcriptional regulator, merr family AOQ81_08285 ENOG4105H67 Protein of unknown function (DUF421) AOQ81_08290 ENOG41080C8 DUF218 domain AOQ81_08345 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AOQ81_08355 ENOG4107R0U MotA TolQ exbB proton channel AOQ81_08360 ENOG4105ER2 Ompa motb domain protein AOQ81_08365 ENOG4107YTP response regulator receiver protein AOQ81_08375 ENOG4105DD5 Flagellar motor switch protein AOQ81_08390 ENOG4105BZU Histidine kinase AOQ81_08410 ENOG4105E1Q flagellar hook-associated protein AOQ81_08415 ENOG4105DTJ flagellar hook-associated protein AOQ81_08440 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AOQ81_08445 ENOG4108ZC9 flagellar basal-body rod protein flgc AOQ81_08450 ENOG41075Z6 flagellar hook-basal body complex protein fliE AOQ81_08455 ENOG4107U2N Flagellar M-ring protein AOQ81_08465 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AOQ81_08500 ENOG4105BZE flagellar hook protein, FlgE AOQ81_08525 ENOG4105K64 Glycosyl transferase, family 2 AOQ81_08555 ENOG4107TVC Glycosyl transferase, family 2 AOQ81_08580 ENOG4105I03 Flagellin AOQ81_08585 ENOG4105E4C Lytic transglycosylase catalytic AOQ81_08600 ENOG4105DD5 Flagellar motor switch protein AOQ81_08610 ENOG4105CN7 Flagellar biosynthetic protein FliP AOQ81_08615 ENOG4105VS8 Flagellar biosynthetic protein fliq AOQ81_08625 ENOG4105D00 flagellar biosynthetic protein flhB AOQ81_08630 ENOG4105D7B Flagellar biosynthesis protein flha AOQ81_08640 ENOG4105KTQ flagellar basal-body rod protein AOQ81_08645 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOQ81_08670 ENOG4108RZE Tetr family transcriptional regulator AOQ81_08690 ENOG4105KAC Antibiotic biosynthesis monooxygenase AOQ81_08715 ENOG4105DUM transcriptional regulator, lysR family AOQ81_08720 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_08725 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AOQ81_08730 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component AOQ81_08735 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AOQ81_08770 ENOG4105CVJ phosphoglycerate mutase AOQ81_08800 ENOG4105CAQ asparagine synthetase AOQ81_08820 ENOG4105PGM cation diffusion facilitator family transporter AOQ81_08830 ENOG4105DRR Transcriptional regulator, GntR family AOQ81_08835 ENOG4108UZ3 Transporter AOQ81_08840 ENOG4105CKI cobalamin synthesis protein AOQ81_08845 ENOG4108PJD permease AOQ81_08860 ENOG4105DFD Na H antiporter AOQ81_08865 ENOG4105C9Q fumarate hydratase class II AOQ81_08895 ENOG4105EC3 peptidase S51, dipeptidase E AOQ81_08915 ENOG4107QIV Cytochrome c biogenesis protein AOQ81_08950 ENOG4106BRA Membrane AOQ81_08985 ENOG4105CJ1 ABC, transporter AOQ81_09005 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) AOQ81_09020 ENOG4105C6K Malic enzyme AOQ81_09090 ENOG4105FVX AOQ81_09130 ENOG4105CSR polyphosphate kinase 2 AOQ81_09150 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AOQ81_09165 ENOG4105EU0 Major facilitator Superfamily AOQ81_09170 ENOG4105C6T cysteine synthase AOQ81_09190 ENOG4105C8J )-transporter AOQ81_09200 ENOG4105X5K response regulator receiver protein AOQ81_09205 ENOG4105H67 Protein of unknown function (DUF421) AOQ81_09220 ENOG4106KE4 Dehydrogenase AOQ81_09235 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AOQ81_09240 ENOG4105CHR reductase AOQ81_09245 ENOG4105CM2 brancheD-chain amino acid aminotransferase AOQ81_09250 ENOG4105C7K acetolactate synthase AOQ81_09255 ENOG4108ZP8 Acetolactate synthase small subunit AOQ81_09260 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AOQ81_09270 ENOG4105C7B Threonine dehydratase AOQ81_09295 ENOG4105C6X Major Facilitator AOQ81_09300 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AOQ81_09310 ENOG4105DY9 regulatoR AOQ81_09315 ENOG4105CYC Transferase AOQ81_09335 ENOG4105F6J Alpha beta hydrolase fold AOQ81_09340 ENOG4108J59 Extracellular solute-binding protein, family 5 AOQ81_09370 ENOG41068WN AOQ81_09390 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AOQ81_09395 ENOG4105C72 UPF0176 protein AOQ81_09405 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AOQ81_09440 ENOG4107RHR regulatoR AOQ81_09450 ENOG4105D9N nucleoside AOQ81_09455 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) AOQ81_09490 ENOG4107RAQ aminopeptidase AOQ81_09495 ENOG4107STQ Multicopper oxidase AOQ81_09540 ENOG4108T5E Copper resistance protein AOQ81_09545 ENOG4105KTB nuclear export factor GLE1 AOQ81_09555 ENOG4107RT3 EamA-like transporter family AOQ81_09560 ENOG4105GZI Transcriptional regulator AOQ81_09565 ENOG4108Z40 Transcriptional regulator AOQ81_09570 ENOG4107ZXU DSBA oxidoreductase AOQ81_09575 ENOG4108TVJ Nitroreductase AOQ81_09585 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AOQ81_09590 ENOG4106F5Q Membrane AOQ81_09595 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOQ81_09605 ENOG4105CKI cobalamin synthesis protein AOQ81_09625 ENOG4108Z7G MaoC domain protein dehydratase AOQ81_09630 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOQ81_09640 ENOG4105C0Z ABC transporter AOQ81_09645 ENOG4108IV0 ABC, transporter AOQ81_09650 ENOG4105C32 Amino acid ABC transporter (Permease) AOQ81_09660 ENOG4105SKE transcriptional Regulator LysR family AOQ81_09670 ENOG4105MDS 4-oxalocrotonate tautomerase AOQ81_09680 ENOG4105YGB Transcriptional regulator AOQ81_09690 ENOG4105C4M (Ubiquinol oxidase) subunit I AOQ81_09695 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AOQ81_09700 ENOG4108JJ9 ABC, transporter AOQ81_09705 ENOG4108JJ8 (ABC) transporter AOQ81_09750 ENOG4105BZ1 (ABC) transporter AOQ81_09755 ENOG4105BZ1 (ABC) transporter AOQ81_09760 ENOG4105EFI regulatoR AOQ81_09765 ENOG4105BZU Histidine kinase AOQ81_09785 ENOG41075D4 Aminoglycoside 6-adenylyltransferase AOQ81_09790 ENOG4108ZJ4 polysaccharide deacetylase AOQ81_09810 ENOG4105D6E homoserine dehydrogenase AOQ81_09835 ENOG4108KGH TRANSCRIPTIONal AOQ81_09845 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_09850 ENOG4105BZU Histidine kinase AOQ81_09855 ENOG4107VMI polysaccharide deacetylase AOQ81_09865 ENOG4105KT7 mgtC SapB transporter AOQ81_09870 ENOG4105VRR gCN5-related N-acetyltransferase AOQ81_09880 ENOG4105DUU IucA IucC family protein AOQ81_09885 ENOG4105CEY Amp-dependent synthetase and ligase AOQ81_09900 ENOG4108WBH protein TIM barrel AOQ81_09905 ENOG4105YWU small acid-soluble spore protein AOQ81_09915 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AOQ81_09965 ENOG4105KRN Transcriptional regulator, abrb family AOQ81_09975 ENOG4105YVS arsR family transcriptional regulator AOQ81_09980 ENOG4107SET aldo keto reductase AOQ81_09985 ENOG4107XZQ multidrug resistance protein AOQ81_10010 ENOG4105C8Q Methyl-accepting chemotaxis AOQ81_10030 ENOG4108K88 Membrane AOQ81_10035 ENOG4108WPJ Ferritin-like domain AOQ81_10050 ENOG4105DEN Luciferase family AOQ81_10070 ENOG4107QM2 Aldo Keto reductase AOQ81_10075 ENOG4105CKI cobalamin synthesis protein AOQ81_10140 ENOG4105DSE periplasmic solute binding protein AOQ81_10150 ENOG4105K4T epimerase AOQ81_10160 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AOQ81_10185 ENOG4105CVJ phosphoglycerate mutase AOQ81_10205 ENOG4107T5V SNARE associated Golgi AOQ81_10220 ENOG4108PJD permease AOQ81_10230 ENOG4108S4H thioesterase Superfamily protein AOQ81_10235 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AOQ81_10255 ENOG4105SXS Protein of unknown function (DUF456) AOQ81_10260 ENOG4105C37 (CBS) domain AOQ81_10280 ENOG4108Z7R Chaperone CsaA AOQ81_10300 ENOG4108ZRV stage ii sporulation protein p AOQ81_10310 ENOG4108VXD carboxy-peptidase AOQ81_10320 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AOQ81_10345 ENOG4108X4Q Hydrolase AOQ81_10355 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AOQ81_10360 ENOG4107RBS Methyltransferase AOQ81_10375 ENOG41087PP glycosyltransferase MGT family AOQ81_10380 ENOG4108JYZ YitT family AOQ81_10385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AOQ81_10410 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) AOQ81_10460 ENOG4105KBJ sporulation protein ytfj AOQ81_10485 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AOQ81_10505 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) AOQ81_10510 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_10520 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AOQ81_10525 ENOG4105EMN RNA polymerase sigma factor AOQ81_10550 ENOG4108V06 Glutathione peroxidase AOQ81_10565 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOQ81_10585 ENOG4108IUE nitrate reductase beta subunit AOQ81_10590 ENOG4105R3A Nitrate reductase AOQ81_10615 ENOG4107V6Q Cyclic nucleotide-binding domain AOQ81_10620 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AOQ81_10625 ENOG4105D06 uba thif-type nad fad binding protein AOQ81_10630 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOQ81_10635 ENOG4108ZAF Molybdopterin AOQ81_10660 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein AOQ81_10665 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein AOQ81_10670 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AOQ81_10675 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit AOQ81_10680 ENOG4108IFG nitrite reductase, (NAD(P)H) AOQ81_10685 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) AOQ81_10720 ENOG4105MCT stage V sporulation protein S AOQ81_10735 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AOQ81_10755 ENOG4105C5H ABC transporter AOQ81_10770 ENOG4108UUM single-stranded DNA-binding protein AOQ81_10785 ENOG41061H0 Monooxygenase AOQ81_10805 ENOG4107YX5 Pfam:DUF548 AOQ81_10810 ENOG4105C75 arginyL-tRNA synthetase AOQ81_10835 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AOQ81_10850 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) AOQ81_10855 ENOG4105C5S asparaginyl-tRNA synthetase AOQ81_10875 ENOG4105EC2 ftsk spoIIIe AOQ81_10970 ENOG4105BZW Glycerate kinase AOQ81_10975 ENOG4107QPK )-transporter AOQ81_10980 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_10985 ENOG41062D9 Histidine kinase AOQ81_11000 ENOG4105C8J )-transporter AOQ81_11020 ENOG4107XGZ Hydrolase AOQ81_11025 ENOG4105CY2 Citrate transporter AOQ81_11030 ENOG4105C0A alcohol dehydrogenase AOQ81_11045 ENOG4105KD7 acetyltransferase AOQ81_11075 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 AOQ81_11095 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) AOQ81_11110 ENOG4107RVG penicillin-binding protein AOQ81_11115 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AOQ81_11120 ENOG4105E9Q Acyl-transferase AOQ81_11125 ENOG4108UT2 hemolysin iii AOQ81_11135 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AOQ81_11145 ENOG4108RCR degv family AOQ81_11150 ENOG4105E8R UPF0173 metal-dependent hydrolase AOQ81_11155 ENOG4108KF3 Electron transport protein SCO1 SenC AOQ81_11160 ENOG4107Y70 Heat shock protein AOQ81_11165 ENOG4105CAQ asparagine synthetase AOQ81_11185 ENOG4108MES Periplasmic binding protein AOQ81_11190 ENOG4105F0I Aminotransferase AOQ81_11225 ENOG4105D8X mechanosensitive ion channel AOQ81_11230 ENOG4105BZU Histidine kinase AOQ81_11235 ENOG4105WH1 Two component transcriptional regulator luxr family AOQ81_11245 ENOG4106KNT transcriptional regulator AOQ81_11280 ENOG4105CMG Carbohydrate kinase AOQ81_11285 ENOG4105CMG Carbohydrate kinase AOQ81_11315 ENOG4108IJ8 ABC transporter AOQ81_11320 ENOG4105E90 ABC transporter AOQ81_11355 ENOG4105C37 (CBS) domain AOQ81_11380 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOQ81_11395 ENOG4107S4Y M20 DapE family protein YgeY AOQ81_11400 ENOG4108TSC N-acetyltransferase AOQ81_11405 ENOG4108JUB Transcriptional regulator AOQ81_11410 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AOQ81_11450 ENOG4108N23 SpoOM-related protein AOQ81_11455 ENOG410841Q phosphoesterase PA-phosphatase related protein AOQ81_11465 ENOG4105SZ6 Thioredoxin AOQ81_11480 ENOG4108IBT Inherit from COG: transposase AOQ81_11580 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AOQ81_11620 ENOG4105BZ4 penicillin-binding protein AOQ81_11630 ENOG4105CZM Major Facilitator AOQ81_11635 ENOG4105W8X HesB YadR YfhF-family protein AOQ81_11645 ENOG4105DXD 2-methylcitrate dehydratase AOQ81_11650 ENOG4105CR4 methylisocitrate lyase AOQ81_11655 ENOG4105C1G acyl-Coa dehydrogenase AOQ81_11660 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AOQ81_11670 ENOG4105N14 lysine exporter protein LysE YggA AOQ81_11675 ENOG4105E39 Enoyl-CoA hydratase AOQ81_11690 ENOG4107RFY SbcCD D subunit AOQ81_11695 ENOG4105EYH Exonuclease AOQ81_11725 ENOG4105FCD Major Facilitator AOQ81_11730 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AOQ81_11735 ENOG4105E4F Isochorismate synthase AOQ81_11740 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AOQ81_11745 ENOG4105WQI isochorismatase AOQ81_11750 ENOG4105CEY Amp-dependent synthetase and ligase AOQ81_11755 ENOG4105WQT MbtH domain protein AOQ81_11760 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_11775 ENOG4105K70 DNA-binding protein AOQ81_11795 ENOG4105BZG amino acid carrier protein AOQ81_11820 ENOG4105FE9 pseudouridine synthase AOQ81_11825 ENOG4105C22 threonyL-tRNA synthetase AOQ81_11840 ENOG4107SKW Inherit from COG: Alpha beta hydrolase AOQ81_11865 ENOG4108D32 Methyltransferase AOQ81_11895 ENOG41081I9 integral membrane protein AOQ81_11910 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AOQ81_11920 ENOG4105EYF MMPL domain protein AOQ81_11945 ENOG4105WCN acetyltransferase AOQ81_11975 ENOG4105C1Q protoporphyrinogen oxidase AOQ81_11985 ENOG41068WN AOQ81_11995 ENOG4105VEQ Cold shock protein AOQ81_12015 ENOG410667J hydrolase AOQ81_12060 ENOG4107V2S Transcriptional regulator AOQ81_12065 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AOQ81_12080 ENOG4105DND Transcriptional regulator AOQ81_12085 ENOG4108RPX mosc domain containing protein AOQ81_12100 ENOG4105BZ1 (ABC) transporter AOQ81_12105 ENOG4105BZ1 (ABC) transporter AOQ81_12125 ENOG4108JCI Transcriptional regulator AOQ81_12155 ENOG4108KPJ rna polymerase sigma factor AOQ81_12180 ENOG4105F32 YngK protein AOQ81_12205 ENOG4105RD7 BadF BadG BcrA BcrD AOQ81_12215 ENOG4107STF Involved in phosphonate degradation (By similarity) AOQ81_12235 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AOQ81_12250 ENOG4105C1J atp-dependent rna helicase AOQ81_12265 ENOG4108RZE Tetr family transcriptional regulator AOQ81_12285 ENOG41088CC tellurite resistance protein tehB AOQ81_12295 ENOG4108I0C methyltransferase AOQ81_12300 ENOG4107RA9 decarboxylase AOQ81_12305 ENOG41090HR transcriptional regulator AOQ81_12345 ENOG4105CIN aminoacyl-histidine dipeptidase AOQ81_12370 ENOG4107RF6 penicillin-binding protein AOQ81_12385 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AOQ81_12390 ENOG4105ETE Transcriptional regulator (LacI family AOQ81_12395 ENOG4105IE8 Alpha-ketoglutarate permease AOQ81_12400 ENOG4105CK5 oxidoreductase AOQ81_12425 ENOG4105D2N Aldolase AOQ81_12430 ENOG4105DH8 myo-inositol catabolism AOQ81_12445 ENOG4105CGH 5'-nucleotidase AOQ81_12455 ENOG4105CGH 5'-nucleotidase AOQ81_12470 ENOG4105VZ8 Transcriptional regulator AOQ81_12485 ENOG4108VXD carboxy-peptidase AOQ81_12505 ENOG41067SE Tetr family transcriptional regulator AOQ81_12510 ENOG4105C5H ABC transporter AOQ81_12520 ENOG4105BZU Histidine kinase AOQ81_12530 ENOG4106ANW SMI1_KNR4 AOQ81_12535 ENOG4105CEP NADH dehydrogenase AOQ81_12540 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AOQ81_12555 ENOG4105CJ1 ABC, transporter AOQ81_12565 ENOG4107Z3H Transcriptional regulator, TetR family AOQ81_12580 ENOG4105C1G acyl-Coa dehydrogenase AOQ81_12585 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AOQ81_12590 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit AOQ81_12595 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase AOQ81_12600 ENOG4105E39 Enoyl-CoA hydratase AOQ81_12605 ENOG4107QX3 carboxylase AOQ81_12610 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AOQ81_12620 ENOG4105WCN acetyltransferase AOQ81_12625 ENOG4105DBI uridine monophosphokinase AOQ81_12660 ENOG4105T9C HD domain AOQ81_12670 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AOQ81_12710 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOQ81_12710 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOQ81_12725 ENOG4105FQP Beta-lactamase AOQ81_12735 ENOG4107Y80 Major Facilitator superfamily AOQ81_12755 ENOG4105CUV Homoserine Kinase AOQ81_12790 ENOG4105CPQ Dehydrogenase AOQ81_12805 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOQ81_12810 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOQ81_12905 ENOG4105ETU transcriptional activator (TenA AOQ81_13015 ENOG410667J hydrolase AOQ81_13025 ENOG4105BZU Histidine kinase AOQ81_13030 ENOG4107RF6 penicillin-binding protein AOQ81_13050 ENOG4108JJB ABC transporter AOQ81_13060 ENOG4108HGU Histidine kinase AOQ81_13075 ENOG4105CB2 alcohol dehydrogenase AOQ81_13080 ENOG4105CJN penicillin-binding protein AOQ81_13090 ENOG4105FQP Beta-lactamase AOQ81_13125 ENOG4108V4B ThiJ pfpI AOQ81_13155 ENOG4107Y80 Major Facilitator superfamily AOQ81_13170 ENOG4107VXM glycerophosphoryl diester phosphodiesterase AOQ81_13190 ENOG4107Y9U Membrane AOQ81_13225 ENOG4105FCD Major Facilitator AOQ81_13240 ENOG4105E09 nadh pyrophosphatase AOQ81_13245 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AOQ81_13250 ENOG4108Z4K mutator MutT protein AOQ81_13285 ENOG4108XI2 Domain of unknown function (DUF1963) AOQ81_13315 ENOG4108NRW Phospholipase, patatin family AOQ81_13320 ENOG4105KWG Pfam:DUF1696 AOQ81_13355 ENOG4105PKS Excinuclease abc c subunit domain protein AOQ81_13395 ENOG4107VFR oxidoreductase AOQ81_13420 ENOG4105PAD Hydrolase AOQ81_13440 ENOG4105DY8 decarboxylase AOQ81_13455 ENOG4108IUM Glycogen debranching enzyme AOQ81_13480 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AOQ81_13490 ENOG4105FDR Membrane AOQ81_13525 ENOG4108V3A UPF0421 protein AOQ81_13545 ENOG4105MSI germination protein ypeb AOQ81_13565 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) AOQ81_13570 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) AOQ81_13575 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) AOQ81_13580 ENOG4107Z3H Transcriptional regulator, TetR family AOQ81_13610 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family AOQ81_13630 ENOG4105E98 transcriptional regulator DeoR family AOQ81_13650 ENOG41062ES Transcriptional regulator AOQ81_13670 ENOG4107QKR Dehydrogenase AOQ81_13680 ENOG4107RUY (E1 component), alpha subunit AOQ81_13690 ENOG4105E1F short-chain dehydrogenase reductase AOQ81_13695 ENOG4105RHY Pfam:UPF0157 AOQ81_13730 ENOG4107SQ8 Glycine betaine AOQ81_13735 ENOG4108IJ7 Glycine betaine AOQ81_13760 ENOG4105E66 phosphoriboisomerase A AOQ81_13765 ENOG41082BV acetyltransferase AOQ81_13770 ENOG4108M1A Chitin-binding protein AOQ81_13815 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AOQ81_13865 ENOG4105EEM helicase AOQ81_13885 ENOG4105C9U ATP-dependent DNA helicase RecQ AOQ81_13940 ENOG4108M1A Chitin-binding protein AOQ81_13955 ENOG4105BZG amino acid carrier protein AOQ81_13960 ENOG4105C26 Dehydrogenase AOQ81_13965 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AOQ81_13970 ENOG4105CTU Proline racemase AOQ81_13975 ENOG4105CTU Proline racemase AOQ81_13980 ENOG41080HI glycine oxidase AOQ81_14020 ENOG4107T5V SNARE associated Golgi AOQ81_14035 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD AOQ81_14040 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AOQ81_14055 ENOG4105DTQ mandelate racemase muconate lactonizing AOQ81_14095 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) AOQ81_14100 ENOG4105BZU Histidine kinase AOQ81_14105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_14145 ENOG4105EPR degv family AOQ81_14185 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) AOQ81_14190 ENOG4106K7D Major facilitator family transporter AOQ81_14210 ENOG4107BMA Transglycosylase associated protein AOQ81_14225 ENOG41089UC methyltransferase, type 11 AOQ81_14260 ENOG4105CHM Aminotransferase AOQ81_14295 ENOG4105DVE abc transporter atp-binding protein AOQ81_14345 ENOG4105C02 permease AOQ81_14360 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AOQ81_14365 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AOQ81_14370 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein AOQ81_14395 ENOG4105E09 nadh pyrophosphatase AOQ81_14415 ENOG4108AQF aminoglycoside N(3)-acetyltransferase AOQ81_14465 ENOG4107VC0 DNA alkylation repair enzyme AOQ81_14475 ENOG4107VMI polysaccharide deacetylase AOQ81_14485 ENOG4108ZCF integral membrane protein AOQ81_14490 ENOG4105E0M Sulfatase AOQ81_14495 ENOG4105C5H ABC transporter AOQ81_14505 ENOG4105EYF MMPL domain protein AOQ81_14510 ENOG4105EYF MMPL domain protein AOQ81_14515 ENOG4105EYF MMPL domain protein AOQ81_14520 ENOG41082JN Transcriptional regulator AOQ81_14540 ENOG4105CIH Imidazole acetol-phosphate transaminase AOQ81_14545 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AOQ81_14550 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AOQ81_14585 ENOG41069ER domain protein AOQ81_14595 ENOG4105EMN RNA polymerase sigma factor AOQ81_14620 ENOG4105D4B ABC, transporter AOQ81_14630 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AOQ81_14640 ENOG4105DKT Transcriptional regulator AOQ81_14655 ENOG41061GT Aldolase AOQ81_14675 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) AOQ81_14705 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AOQ81_14710 ENOG4105II7 pyrroline-5-carboxylate reductase AOQ81_14720 ENOG4107258 Transcriptional regulator AOQ81_14730 ENOG4105E0Y RtcB Protein AOQ81_14735 ENOG4105ECK Fatty Acid Desaturase AOQ81_14740 ENOG4105G6Z alkaline phosphatase AOQ81_14750 ENOG4105VMP Transcriptional regulator AOQ81_14765 ENOG41090T1 Membrane AOQ81_14775 ENOG4108WCX response regulator AOQ81_14785 ENOG41068WN AOQ81_14810 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOQ81_14835 ENOG4105CKK Glycosyl transferase, family 2 AOQ81_14860 ENOG4105CKK Glycosyl transferase, family 2 AOQ81_14870 ENOG4105C8Y Acetylornithine aminotransferase AOQ81_14910 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AOQ81_14920 ENOG4108TVJ Nitroreductase AOQ81_14925 ENOG4105FS7 Transcriptional regulator AOQ81_14960 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOQ81_14970 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AOQ81_15000 ENOG4108XET gCN5-related N-acetyltransferase AOQ81_15080 ENOG410635A Membrane AOQ81_15085 ENOG4105KNA -acetyltransferase AOQ81_15090 ENOG4108IQI permease AOQ81_15100 ENOG4105F1N DNA alkylation repair AOQ81_15140 ENOG4107RF6 penicillin-binding protein AOQ81_15150 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AOQ81_15190 ENOG4105P4J Allophanate hydrolase, subunit 1 AOQ81_15195 ENOG4107258 Transcriptional regulator AOQ81_15205 ENOG4106N3A copper homeostasis protein cutc AOQ81_15210 ENOG4108ZRV stage ii sporulation protein p AOQ81_15215 ENOG4108ZHR arsR family transcriptional regulator AOQ81_15225 ENOG4105FDT acyl-CoA dehydrogenase AOQ81_15245 ENOG4105DWD nucleoside recognition domain protein AOQ81_15275 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AOQ81_15340 ENOG4105E2A Dehydrogenase AOQ81_15355 ENOG4108IJ0 Aspartate ammonia-lyase AOQ81_15360 ENOG4105HDK L-asparaginase AOQ81_15365 ENOG4108IMY Transcriptional regulator AOQ81_15375 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AOQ81_15380 ENOG4105CUB amino acid AOQ81_15390 ENOG4105II7 pyrroline-5-carboxylate reductase AOQ81_15400 ENOG4105C6K Malic enzyme AOQ81_15410 ENOG4108NHD germination protein AOQ81_15415 ENOG4108NHD germination protein AOQ81_15420 ENOG4108Q8B Spore germination protein AOQ81_15440 ENOG4105CSV Glutaminase AOQ81_15470 ENOG4105CGH 5'-nucleotidase AOQ81_15475 ENOG4105CH6 catalase AOQ81_15485 ENOG4105CHJ isochorismatase hydrolase AOQ81_15550 ENOG4108606 TspO/MBR family AOQ81_15555 ENOG4105CVP deoxyribo-dipyrimidine photolyase AOQ81_15570 ENOG4108TWJ NADH dehydrogenase subunit 5 AOQ81_15575 ENOG4105GPN Uncharacterized conserved protein (DUF2294) AOQ81_15585 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AOQ81_15590 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) AOQ81_15595 ENOG4105DSE periplasmic solute binding protein AOQ81_15600 ENOG4105CC5 ABC transporter AOQ81_15605 ENOG4105DIK (ABC) transporter AOQ81_15635 ENOG4105D6J arsenicaL-resistance protein AOQ81_15640 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_15645 ENOG41085FC arsR family transcriptional regulator AOQ81_15660 ENOG4105F7F Chaperone AOQ81_15670 ENOG4105CHR reductase AOQ81_15675 ENOG4108YXU transcriptional regulator AsnC family AOQ81_15750 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AOQ81_15760 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_15770 ENOG4105IIP Membrane AOQ81_15785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_15790 ENOG41062D9 Histidine kinase AOQ81_15820 ENOG4105K6H D-cysteine desulfhydrase AOQ81_15845 ENOG4105VZ8 Transcriptional regulator AOQ81_15860 ENOG4108NNI Beta-lactamase domain-containing protein AOQ81_15865 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AOQ81_15875 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AOQ81_15880 ENOG4105JQZ Methyltransferase AOQ81_15895 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AOQ81_15900 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) AOQ81_15920 ENOG4105BZU Histidine kinase AOQ81_15935 ENOG4108U05 Transcriptional regulator AOQ81_15950 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) AOQ81_15955 ENOG4105DJB Major Facilitator Superfamily AOQ81_15960 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) AOQ81_15965 ENOG4107QR9 Iron-sulfur cluster binding protein AOQ81_15975 ENOG4106P55 Transcriptional regulator AOQ81_15985 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AOQ81_16020 ENOG4105TRI Hydrolase AOQ81_16055 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AOQ81_16085 ENOG4107QJQ Mate efflux family protein AOQ81_16100 ENOG4105EQ0 Major Facilitator superfamily AOQ81_16105 ENOG4108JGH Tetr family transcriptional regulator AOQ81_16120 ENOG4105C44 Serine transporter AOQ81_16125 ENOG4105EJQ L-serine dehydratase AOQ81_16140 ENOG4108JPW Aminotransferase AOQ81_16155 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) AOQ81_16165 ENOG4105DVH amino acid AOQ81_16180 ENOG4108JQ1 Dehydrogenase AOQ81_16200 ENOG4108AEY RNA polymerase sigma factor AOQ81_16215 ENOG41082W1 Cupin 2, conserved barrel domain protein AOQ81_16225 ENOG410874W AraC family transcriptional regulator AOQ81_16240 ENOG4105HIR S-layer domain protein AOQ81_16280 ENOG4108ISG Major Facilitator AOQ81_16290 ENOG4107MII Sugar-specific transcriptional regulator TrmB AOQ81_16295 ENOG4105CZM Major Facilitator AOQ81_16315 ENOG4105DA5 (ABC) transporter AOQ81_16320 ENOG41069JR AOQ81_16330 ENOG4105RXJ AOQ81_16335 ENOG4105KPY Small multidrug resistance protein AOQ81_16340 ENOG4105KBX Transcriptional regulator, TetR family AOQ81_16355 ENOG4105CRW Short chain fatty acid transporter AOQ81_16365 ENOG4105DYS nad(p)h dehydrogenase (quinone) AOQ81_16395 ENOG4108JJB ABC transporter AOQ81_16400 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) AOQ81_16425 ENOG4108K8S endonuclease I AOQ81_16440 ENOG41067QW Transcriptional regulator AOQ81_16450 ENOG4108Z66 YbaK ebsC protein AOQ81_16455 ENOG4105CUT histidyl-tRNA synthetase AOQ81_16470 ENOG4105KVH Transcriptional regulator AOQ81_16475 ENOG4108RCM Nitroreductase AOQ81_16495 ENOG4108PSK reductase AOQ81_16505 ENOG4105CJ1 ABC, transporter AOQ81_16565 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_16570 ENOG4105DKQ ROK family AOQ81_16575 ENOG4106UW1 Major Facilitator superfamily AOQ81_16580 ENOG4108UW5 maltose o-acetyltransferase AOQ81_16595 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AOQ81_16600 ENOG4105C31 Tryptophanyl-tRNA synthetase AOQ81_16605 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AOQ81_16630 ENOG4105DMQ Methyltransferase AOQ81_16640 ENOG4105EV4 Multidrug resistance protein mdtH AOQ81_16670 ENOG4105C37 (CBS) domain AOQ81_16685 ENOG4105DDN Pentapeptide repeat-containing protein AOQ81_16690 ENOG4105XDF Protein of unknown function (DUF1272) AOQ81_16695 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) AOQ81_16700 ENOG4105CMG Carbohydrate kinase AOQ81_16705 ENOG4105C6Z Gluconate AOQ81_16710 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AOQ81_16725 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AOQ81_16730 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AOQ81_16735 ENOG4105CIS alcohol dehydrogenase AOQ81_16740 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone AOQ81_16760 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AOQ81_16765 ENOG4105D4Y metalloprotease AOQ81_16785 ENOG4105CV8 reductase AOQ81_16790 ENOG4105F27 Major Facilitator AOQ81_16805 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) AOQ81_16810 ENOG4105C44 Serine transporter AOQ81_16845 ENOG4105KVH Transcriptional regulator AOQ81_16850 ENOG4108TZY GntR Family Transcriptional Regulator AOQ81_16860 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AOQ81_16865 ENOG4105KVH Transcriptional regulator AOQ81_16870 ENOG4105KVH Transcriptional regulator AOQ81_16905 ENOG4105JAB phenazine biosynthesis protein, phzf family AOQ81_16915 ENOG4105CHR reductase AOQ81_16935 ENOG4105KVH Transcriptional regulator AOQ81_17005 ENOG4105KAF membrAne AOQ81_17030 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) AOQ81_17045 ENOG4107YXZ hydrolase, family 25 AOQ81_17070 ENOG4105ED2 Beta-lactamase AOQ81_17080 ENOG4105H3G oxidoreductase AOQ81_17155 ENOG4108TN2 lmbE family AOQ81_17165 ENOG4107R3E Citrate transporter AOQ81_17185 ENOG4108MES Periplasmic binding protein AOQ81_17195 ENOG4105EHG Permease protein AOQ81_17200 ENOG4105DQ5 transport system permease protein AOQ81_17205 ENOG4105NX3 Membrane AOQ81_17210 ENOG4107ZY0 Phenazine biosynthesis-like protein AOQ81_17230 ENOG4107CUJ Protein of unknown function (DUF2690) AOQ81_17240 ENOG4107V2S Transcriptional regulator AOQ81_17260 ENOG4105C98 muts2 protein AOQ81_17270 ENOG4105E5K Alpha-amylase AOQ81_17275 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase AOQ81_17280 ENOG4105DPN Oligoendopeptidase f AOQ81_17285 ENOG4108A04 Beta-lactamase AOQ81_17315 ENOG4107VXM glycerophosphoryl diester phosphodiesterase AOQ81_17340 ENOG41082BM Transcriptional regulator, arsr family AOQ81_17345 ENOG4105CIS alcohol dehydrogenase AOQ81_17370 ENOG4105RHY Pfam:UPF0157 AOQ81_17380 ENOG4105C09 Bile acid AOQ81_17385 ENOG4105CQB FAD linked oxidase domain protein AOQ81_17410 ENOG4108UT6 Transferase hexapeptide repeat containing protein AOQ81_17420 ENOG4105K64 Glycosyl transferase, family 2 AOQ81_17425 ENOG4105E39 Enoyl-CoA hydratase AOQ81_17435 ENOG4105KT7 mgtC SapB transporter AOQ81_17445 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_17450 ENOG41073R8 VanW family AOQ81_17460 ENOG4108R1P AOQ81_17480 ENOG4105VEQ Cold shock protein AOQ81_17500 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) AOQ81_17520 ENOG410904N short-chain dehydrogenase reductase AOQ81_17530 ENOG4106IQC argininosuccinate lyase AOQ81_17545 ENOG4108IA2 Sodium pantothenate symporter AOQ81_17555 ENOG4105C26 Dehydrogenase AOQ81_17560 ENOG4105CHR reductase AOQ81_17570 ENOG4105EWU Squalene--hopene cyclase AOQ81_17580 ENOG4105FR1 rard protein AOQ81_17585 ENOG410696E Membrane AOQ81_17600 ENOG4105D1F ATP-binding protein AOQ81_17610 ENOG4108ZAF Molybdopterin AOQ81_17615 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOQ81_17620 ENOG4105D06 uba thif-type nad fad binding protein AOQ81_17625 ENOG4105TMB Formate nitrite transporter AOQ81_17635 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AOQ81_17640 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) AOQ81_17650 ENOG4108JB9 formate dehydrogenase AOQ81_17660 ENOG4105E1K spore germination protein AOQ81_17720 ENOG4107QJT sodium dicarboxylate symporter AOQ81_17725 ENOG4108KGH TRANSCRIPTIONal AOQ81_17735 ENOG4105EMN RNA polymerase sigma factor AOQ81_17760 ENOG4105CIG ABC transporter AOQ81_17770 ENOG4105D9R oxidoreductase AOQ81_17780 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AOQ81_17790 ENOG4105K4P CoA-binding domain protein AOQ81_17795 ENOG4105C0H protease AOQ81_17800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_17810 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AOQ81_17815 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) AOQ81_17820 ENOG4105W8X HesB YadR YfhF-family protein AOQ81_17850 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AOQ81_17855 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AOQ81_17865 ENOG4108JJA ABC, transporter AOQ81_17870 ENOG4108I0Z Aconitate hydratase AOQ81_17900 ENOG4105E5W Transporter AOQ81_17910 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOQ81_17930 ENOG4107F3J Amp-dependent synthetase and ligase AOQ81_17935 ENOG4107ZYJ bioY protein AOQ81_17940 ENOG4105CEY Amp-dependent synthetase and ligase AOQ81_17985 ENOG4107AYK membrAne AOQ81_17995 ENOG4105BZU Histidine kinase AOQ81_18000 ENOG4105FBA Phospholipase Carboxylesterase AOQ81_18005 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase AOQ81_18010 ENOG4105CK7 Sodium proline symporter AOQ81_18015 ENOG4105CBC glutamate synthase AOQ81_18020 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AOQ81_18025 ENOG4108VJ1 Transcriptional regulator (CarD family AOQ81_18030 ENOG4108903 Formimidoylglutamase AOQ81_18055 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) AOQ81_18115 ENOG4107QIV Cytochrome c biogenesis protein AOQ81_18125 ENOG4107RSM transcriptional regulator AOQ81_18130 ENOG4105VAW lrga family AOQ81_18135 ENOG41067MG lrgb family AOQ81_18160 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AOQ81_18175 ENOG4105BZ1 (ABC) transporter AOQ81_18180 ENOG4105BZ1 (ABC) transporter AOQ81_18200 ENOG4105D7V transposase AOQ81_18220 ENOG4105D5T phosphonate abc transporter AOQ81_18235 ENOG4105CGH 5'-nucleotidase AOQ81_18245 ENOG4108SVB resolvase AOQ81_18265 ENOG4105K7K Transcriptional regulator AOQ81_18300 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase AOQ81_18305 ENOG4105XSJ toxin secretion phage lysis holin AOQ81_18515 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) AOQ81_18620 ENOG4105C5F glutamine synthetase AOQ81_18625 ENOG4105KV4 Transcriptional regulator AOQ81_18630 ENOG4105CXI aluminum resistance protein AOQ81_18640 ENOG4105EN6 Membrane AOQ81_18645 ENOG4106F1P AAA ATPase, central domain protein AOQ81_18675 ENOG41069ER domain protein AOQ81_18680 ENOG4105DM4 PTS System AOQ81_18685 ENOG4105DE4 1-phosphofructokinase AOQ81_18690 ENOG4105E98 transcriptional regulator DeoR family AOQ81_18700 ENOG4108SJC Membrane AOQ81_18715 ENOG4105C85 amino acid AOQ81_18730 ENOG4105TMB Formate nitrite transporter AOQ81_18735 ENOG4105K70 DNA-binding protein AOQ81_18740 ENOG4105C59 p-type ATPase AOQ81_18745 ENOG410681U heavy metal transport detoxification protein AOQ81_18750 ENOG4105VPX protein, conserved in bacteria AOQ81_18760 ENOG4105NIV Esterase AOQ81_18765 ENOG4105E0A ABC, transporter AOQ81_18790 ENOG4105CGK Exodeoxyribonuclease III AOQ81_18800 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AOQ81_18805 ENOG4105D03 DNA-3-methyladenine glycosylase II AOQ81_18835 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_18840 ENOG4105BZU Histidine kinase AOQ81_18860 ENOG41067MG lrgb family AOQ81_18875 ENOG4107TTQ Alpha beta hydrolase fold AOQ81_18880 ENOG4107YEI lmbE family AOQ81_18900 ENOG4105F0V Cell wall hydrolase AOQ81_18905 ENOG4107R6R udp-galactopyranose mutase AOQ81_18910 ENOG4105E0M Sulfatase AOQ81_18915 ENOG410890F Dynamin family AOQ81_18925 ENOG4107QHE Choloylglycine hydrolase AOQ81_18950 ENOG4105DA5 (ABC) transporter AOQ81_18975 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AOQ81_18980 ENOG4105DQU oxidoreductase, subunit beta AOQ81_18985 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein AOQ81_18990 ENOG4108IGT Dipeptidase AOQ81_18995 ENOG4105MCT stage V sporulation protein S AOQ81_19000 ENOG4105D48 metallophosphoesterase AOQ81_19025 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AOQ81_19040 ENOG4105XZV Protein of unknown function (DUF3243) AOQ81_19045 ENOG4108RKS Short-chain dehydrogenase reductase Sdr AOQ81_19065 ENOG4105UIB (ABC) transporter AOQ81_19070 ENOG4105UIB (ABC) transporter AOQ81_19075 ENOG4108JQ9 ABC transporter AOQ81_19080 ENOG4105DIH basic membrane AOQ81_19085 ENOG4105FDP GntR family transcriptional regulator AOQ81_19090 ENOG4107QZI cell division protein FtsK AOQ81_19100 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit AOQ81_19115 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AOQ81_19125 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AOQ81_19130 ENOG4108S0H Dipicolinic acid synthetase, b subunit AOQ81_19135 ENOG4105E35 Dipicolinate synthase subunit A AOQ81_19145 ENOG4105C1V Peptidase, M16 AOQ81_19165 ENOG4105DTN riboflavin biosynthesis protein ribF AOQ81_19170 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AOQ81_19180 ENOG4105W7A Protein of unknown function (DUF503) AOQ81_19190 ENOG4105VHM ribosomal protein AOQ81_19195 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination AOQ81_19200 ENOG4105CHV Transcription elongation factor NusA AOQ81_19210 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AOQ81_19220 ENOG4105DZP Membrane-associated zinc metalloprotease AOQ81_19225 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) AOQ81_19230 ENOG4105KNE Phosphatidate cytidylyltransferase AOQ81_19235 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AOQ81_19275 ENOG4108HE4 integrase family AOQ81_19285 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AOQ81_19295 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AOQ81_19310 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) AOQ81_19335 ENOG4105VB6 UPF0109 protein AOQ81_19355 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AOQ81_19360 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) AOQ81_19375 ENOG4105CHR reductase AOQ81_19380 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AOQ81_19395 ENOG4105CB5 ATP-dependent DNA helicase recG AOQ81_19400 ENOG4105DP4 dak2 domain fusion protein ylov AOQ81_19405 ENOG4108ZAA Alkaline-shock protein AOQ81_19420 ENOG4105FJ0 thiamine AOQ81_19425 ENOG4105DJV ribulose-phosphate 3-epimerase AOQ81_19430 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AOQ81_19435 ENOG4105D9P serine threonine protein kinase AOQ81_19440 ENOG4108ZF3 Phosphatase AOQ81_19450 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AOQ81_19460 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AOQ81_19465 ENOG4105C25 Primosomal protein n' AOQ81_19470 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AOQ81_19490 ENOG4105DSJ YicC domain protein AOQ81_19500 ENOG4105F23 Fibronectin-binding protein AOQ81_19505 ENOG4105DC7 peptidase M24 AOQ81_19560 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AOQ81_19585 ENOG4105C34 Pseudouridine synthase AOQ81_19600 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AOQ81_19610 ENOG4105DBK s4 domain protein AOQ81_19615 ENOG41067XK integral membrane protein AOQ81_19625 ENOG4105DFA alanine racemase domain protein AOQ81_19630 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AOQ81_19635 ENOG4105WR5 sporulation protein, YlmC YmxH family AOQ81_19645 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_19655 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AOQ81_19660 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AOQ81_19665 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) AOQ81_19670 ENOG4105D4A Cell wall formation (By similarity) AOQ81_19675 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AOQ81_19680 ENOG4105CNI cell division protein FtsW AOQ81_19695 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AOQ81_19700 ENOG4105CJN penicillin-binding protein AOQ81_19705 ENOG4105CJN penicillin-binding protein AOQ81_19710 ENOG41068DC Essential cell division protein (By similarity) AOQ81_19745 ENOG4105KNH Nucleic acid-binding protein AOQ81_19795 ENOG4105XSJ toxin secretion phage lysis holin AOQ81_19880 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AOQ81_19890 ENOG4105CAR Terminase, large subunit AOQ81_19980 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AOQ81_19990 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_20045 ENOG4108IMY Transcriptional regulator AOQ81_20070 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) AOQ81_20080 ENOG41063PX domain protein AOQ81_20085 ENOG4105D78 K07001 NTE family protein AOQ81_20090 ENOG4105H20 Sporulation integral membrane protein YlbJ AOQ81_20100 ENOG4106H78 methyltransferase AOQ81_20120 ENOG4107TB6 phosphoglycerate mutase AOQ81_20135 ENOG4106UY4 Inherit from COG: Scp-like extracellular AOQ81_20185 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) AOQ81_20190 ENOG4105CNI cell division protein FtsW AOQ81_20205 ENOG4108IAB Phoh family AOQ81_20225 ENOG4105QA2 AOQ81_20230 ENOG4105CI3 gtp-binding protein typa AOQ81_20240 ENOG4105ECY inositol monophosphatase AOQ81_20260 ENOG4105CXN decarboxylase AOQ81_20305 ENOG4105C7S Dehydrogenase AOQ81_20310 ENOG4105CPP Dehydrogenase, E1 component AOQ81_20325 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AOQ81_20330 ENOG4108X4Q Hydrolase AOQ81_20340 ENOG4105CN5 Metallo-Beta-Lactamase AOQ81_20345 ENOG4107ZYR domain protein AOQ81_20380 ENOG4108XRC Protein of unknown function (DUF458) AOQ81_20390 ENOG4107IN1 Protein of unknown function (DUF1797) AOQ81_20405 ENOG4105EPM Diguanylate phosphodiesterase AOQ81_20410 ENOG4105K6S Short-chain dehydrogenase reductase Sdr AOQ81_20425 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AOQ81_20435 ENOG4105UIN AOQ81_20500 ENOG4108HGU Histidine kinase AOQ81_20510 ENOG4105CHM Aminotransferase AOQ81_20515 ENOG4105FKQ transcriptional regulator AOQ81_20520 ENOG4105EG2 ABC transporter, permease AOQ81_20530 ENOG4107FKK extracellular solute-binding protein family 1 AOQ81_20540 ENOG4105CG3 alpha amylase, catalytic region AOQ81_20585 ENOG4105CHU acetyl-coa acetyltransferase AOQ81_20625 ENOG4105K7K Transcriptional regulator AOQ81_20630 ENOG4105DTD Dehydrogenase AOQ81_20640 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) AOQ81_20650 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AOQ81_20675 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) AOQ81_20695 ENOG4106TD9 Diguanylate cyclase AOQ81_20715 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AOQ81_20730 ENOG4105CID antiterminator AOQ81_20740 ENOG4105FDP GntR family transcriptional regulator AOQ81_20750 ENOG4105CE4 GlcNAc 6-P deacetylase AOQ81_20795 ENOG4107ZE5 PPIases accelerate the folding of proteins AOQ81_20800 ENOG4105PTM secreted protein AOQ81_20805 ENOG4105J7I hydrolase AOQ81_20815 ENOG4105G6R Stage v sporulation protein ae AOQ81_20825 ENOG4105CZ3 stage V sporulation protein ad AOQ81_20830 ENOG41090VF Stage v sporulation protein ac AOQ81_20850 ENOG4105C8J )-transporter AOQ81_20855 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_20865 ENOG41082AN stage II sporulation protein AOQ81_20870 ENOG4105DZ1 carboxypeptidase AOQ81_20875 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOQ81_20880 ENOG4105DVE abc transporter atp-binding protein AOQ81_20915 ENOG4105D7N magnesium and cobalt transport protein CorA AOQ81_20940 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AOQ81_20950 ENOG4105I3K Ferric uptake regulator, Fur family AOQ81_20955 ENOG4105MZ9 stage II sporulation protein m AOQ81_20975 ENOG4105CPC Aldo Keto reductase AOQ81_20985 ENOG4105RHY Pfam:UPF0157 AOQ81_21005 ENOG4107SKW Inherit from COG: Alpha beta hydrolase AOQ81_21015 ENOG4105ETE Transcriptional regulator (LacI family AOQ81_21020 ENOG4108YM7 Gcn5-related n-acetyltransferase AOQ81_21040 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AOQ81_21045 ENOG4108R6K riboflavin synthase, subunit alpha AOQ81_21065 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AOQ81_21070 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOQ81_21075 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AOQ81_21080 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AOQ81_21090 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AOQ81_21100 ENOG4105DFD Na H antiporter AOQ81_21105 ENOG4105CGH 5'-nucleotidase AOQ81_21145 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AOQ81_21160 ENOG4108IXY short-chain dehydrogenase reductase AOQ81_21165 ENOG41069FQ Metallo-beta-lactamase superfamily AOQ81_21175 ENOG4105II7 pyrroline-5-carboxylate reductase AOQ81_21180 ENOG4105EJQ L-serine dehydratase AOQ81_21205 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AOQ81_21215 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AOQ81_21220 ENOG4105D9U N-acetyltransferase AOQ81_21235 ENOG4108VZI ErfK ybiS ycfS ynhG family protein AOQ81_21240 ENOG4108QEG Membrane AOQ81_21245 ENOG4105CDA abc transporter atp-binding protein AOQ81_21250 ENOG4105E5Q amino acid AbC transporter AOQ81_21255 ENOG4108HW3 (ABC) transporter AOQ81_21265 ENOG4105G7B Protein of unknown function (DUF2992) AOQ81_21285 ENOG4105C7S Dehydrogenase AOQ81_21290 ENOG4105CPP Dehydrogenase, E1 component AOQ81_21310 ENOG4107RDP Dehydrogenase AOQ81_21325 ENOG4108JUB Transcriptional regulator AOQ81_21335 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AOQ81_21350 ENOG4107QQR Sporulation AOQ81_21360 ENOG4105S1Z Stage IV sporulation protein B AOQ81_21365 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AOQ81_21375 ENOG4105DX0 Hemolysin A AOQ81_21385 ENOG4105CTB Polyprenyl synthetase AOQ81_21410 ENOG4108ZSR alkaline shock protein AOQ81_21415 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AOQ81_21440 ENOG410644B Stage III sporulation protein af AOQ81_21450 ENOG4105KQ4 Stage iii sporulation protein ad AOQ81_21455 ENOG4108CQH stage III sporulation protein AC AOQ81_21460 ENOG4105KR5 Stage iii sporulation protein AOQ81_21465 ENOG4105CD2 stage iii sporulation protein aa AOQ81_21490 ENOG4105DC7 peptidase M24 AOQ81_21505 ENOG4105CBJ Metal-dependent enzyme AOQ81_21515 ENOG4107YBY Hydrolase AOQ81_21535 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) AOQ81_21540 ENOG4105WZW rhodanese family AOQ81_21580 ENOG4105CJ1 ABC, transporter AOQ81_21585 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AOQ81_21615 ENOG4105C0D helicase AOQ81_21735 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AOQ81_21740 ENOG4105C3R Methionine synthase AOQ81_21755 ENOG4105C28 cystathionine AOQ81_21760 ENOG4105C28 cystathionine AOQ81_21785 ENOG4105C5X domain protein AOQ81_21795 ENOG4105DKQ ROK family AOQ81_21805 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AOQ81_21820 ENOG4108UTW Plays a role in the regulation of phosphate uptake AOQ81_21825 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AOQ81_21830 ENOG4105E2Z phosphate ABC transporter (Permease AOQ81_21835 ENOG4105C8U phosphate abc transporter AOQ81_21840 ENOG4105PWN phosphate abc transporter AOQ81_21845 ENOG4107RF6 penicillin-binding protein AOQ81_21855 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOQ81_21880 ENOG4105N80 Ferric uptake regulator, Fur family AOQ81_21890 ENOG4105FDK ABC transporter AOQ81_21895 ENOG4108JYZ YitT family AOQ81_21900 ENOG41069ZM Protein of unknown function (DUF2624) AOQ81_21925 ENOG4105EGD dinuclear metal center protein, YbgI family AOQ81_21940 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_21945 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AOQ81_21980 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AOQ81_21985 ENOG4105KG3 cytidine deaminase AOQ81_21990 ENOG4107YR5 Diacylglycerol kinase AOQ81_22000 ENOG4105CTJ Metal Dependent Phosphohydrolase AOQ81_22005 ENOG4105C9A Phoh family AOQ81_22020 ENOG41068P3 sporulation protein YqfC AOQ81_22025 ENOG4105KTH gatB Yqey AOQ81_22035 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AOQ81_22040 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AOQ81_22060 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AOQ81_22070 ENOG4105CSA Coproporphyrinogen iii oxidase AOQ81_22075 ENOG4105KVH Transcriptional regulator AOQ81_22100 ENOG4105TQK DNA polymerase iii, delta' subunit AOQ81_22110 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AOQ81_22115 ENOG4108UK2 deaminase AOQ81_22120 ENOG4105KQC Competence protein AOQ81_22130 ENOG4105DXX methyltransferase AOQ81_22140 ENOG4108WF2 Metal Dependent Phosphohydrolase AOQ81_22150 ENOG410812S Rna-binding protein AOQ81_22160 ENOG4105CQW ribosome biogenesis GTPase YqeH AOQ81_22165 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase AOQ81_22180 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_22200 ENOG4108TVJ Nitroreductase AOQ81_22215 ENOG4105G6Z alkaline phosphatase AOQ81_22225 ENOG4108MUZ hydrolase AOQ81_22260 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin AOQ81_22265 ENOG4105MIR Phenylalanine 4-monooxygenase AOQ81_22275 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_22280 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_22320 ENOG4105S6R Iron-hydroxamate transporter permease subunit AOQ81_22325 ENOG4108V5C ABC transporter AOQ81_22335 ENOG4108EKI Dehydrogenase AOQ81_22340 ENOG4105C28 cystathionine AOQ81_22370 ENOG4107XRG penicillin-binding protein AOQ81_22385 ENOG4105CFP Peptidase U32 AOQ81_22390 ENOG4105XYU peptidase (U32 family) AOQ81_22395 ENOG4108VQJ O-methyltransferase AOQ81_22400 ENOG4105HHA aminodeoxychorismate lyase AOQ81_22420 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AOQ81_22430 ENOG4105C02 permease AOQ81_22445 ENOG41060CR AOQ81_22450 ENOG4105C7H Helicase, RecD TraA family AOQ81_22460 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AOQ81_22465 ENOG4105C3J Cysteine desulfurase AOQ81_22475 ENOG4105D1H recombination factor protein RarA AOQ81_22480 ENOG4108VCI transcription factor, rsfa family AOQ81_22485 ENOG4105CUZ uba thif-type nad fad binding protein AOQ81_22495 ENOG4105CUT histidyl-tRNA synthetase AOQ81_22510 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AOQ81_22520 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AOQ81_22525 ENOG41076HS cation diffusion facilitator family transporter AOQ81_22530 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AOQ81_22540 ENOG4105CKP Polysaccharide Biosynthesis Protein AOQ81_22545 ENOG4108QG2 Membrane AOQ81_22555 ENOG4105VIE preprotein translocase, subunit YajC AOQ81_22570 ENOG41061AI Protein of unknown function (DUF2905) AOQ81_22585 ENOG4108HUF Transporter AOQ81_22595 ENOG4108IPJ Membrane AOQ81_22600 ENOG4108IPJ Membrane AOQ81_22605 ENOG41082BM Transcriptional regulator, arsr family AOQ81_22630 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AOQ81_22635 ENOG4108IYU L-aspartate oxidase AOQ81_22650 ENOG4108RPX mosc domain containing protein AOQ81_22655 ENOG4105CQC Prephenate dehydratase AOQ81_22675 ENOG4105EWM Histidine kinase AOQ81_22690 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AOQ81_22705 ENOG4105X36 (ribosomal) protein AOQ81_22715 ENOG4105C03 ribonuclease AOQ81_22730 ENOG4107QMS site-determining protein AOQ81_22745 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AOQ81_22750 ENOG4105DFF Rod shape-determining protein mreb AOQ81_22770 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AOQ81_22775 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AOQ81_22785 ENOG41068KH stage VI sporulation protein D AOQ81_22795 ENOG4105D52 delta-aminolevulinic acid dehydratase AOQ81_22820 ENOG4105K56 Transcriptional regulator AOQ81_22840 ENOG4108IUQ atp-dependent protease AOQ81_22870 ENOG4108QCI YvbH-like oligomerisation region AOQ81_22890 ENOG4105M59 Phosphodiesterase, mj0936 family AOQ81_22895 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AOQ81_22905 ENOG4108XJQ germination protein AOQ81_22915 ENOG4108PCX Major Facilitator AOQ81_22925 ENOG4105KBX Transcriptional regulator, TetR family AOQ81_22940 ENOG4105PFC Transcriptional regulator AOQ81_22955 ENOG4105DZC cytosine deaminase AOQ81_22960 ENOG4105DZC cytosine deaminase AOQ81_22965 ENOG4105DEF Extracellular solute-binding protein, family 5 AOQ81_22970 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AOQ81_22985 ENOG4108JQ7 (ABC) transporter AOQ81_22990 ENOG4108HRK Histidine kinase AOQ81_22995 ENOG4105DY9 regulatoR AOQ81_23010 ENOG41067S9 phage shock protein C, PspC AOQ81_23015 ENOG4108JCI Transcriptional regulator AOQ81_23025 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AOQ81_23030 ENOG4108Z40 Transcriptional regulator AOQ81_23035 ENOG4105RHA ABC transporter, permease AOQ81_23040 ENOG4108IUX (ABC) transporter AOQ81_23045 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family AOQ81_23055 ENOG4105E14 MotA TolQ exbB proton channel AOQ81_23060 ENOG4108VXD carboxy-peptidase AOQ81_23070 ENOG4105E33 succinate dehydrogenase AOQ81_23080 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit AOQ81_23095 ENOG4105K63 Thioredoxin AOQ81_23100 ENOG4105C10 Electron transfer flavoprotein AOQ81_23105 ENOG4105BZJ Electron transfer flavoprotein AOQ81_23110 ENOG41060WC Enoyl-CoA hydratase AOQ81_23115 ENOG4107Z3H Transcriptional regulator, TetR family AOQ81_23120 ENOG4105CEY Amp-dependent synthetase and ligase AOQ81_23130 ENOG4105J76 Periplasmic binding protein AOQ81_23135 ENOG4105S6R Iron-hydroxamate transporter permease subunit AOQ81_23180 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_23195 ENOG4105DR4 Methyltransferase AOQ81_23210 ENOG4105KFN sortase, SrtB family AOQ81_23215 ENOG4105E0A ABC, transporter AOQ81_23230 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) AOQ81_23240 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) AOQ81_23250 ENOG4105FE9 pseudouridine synthase AOQ81_23265 ENOG4105DCG PHP domain protein AOQ81_23300 ENOG4105C5S asparaginyl-tRNA synthetase AOQ81_23305 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AOQ81_23315 ENOG4108RWN rrna methyltransferase AOQ81_23350 ENOG4105C0R drug resistance transporter emrb qaca subfamily AOQ81_23355 ENOG4105CW7 secretion protein, HlyD family AOQ81_23360 ENOG4108JGH Tetr family transcriptional regulator AOQ81_23365 ENOG4105CN9 Peptidase m42 family protein AOQ81_23385 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AOQ81_23390 ENOG4105C22 threonyL-tRNA synthetase AOQ81_23395 ENOG4108TDW sporulation protein YtxC AOQ81_23415 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AOQ81_23420 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AOQ81_23425 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AOQ81_23435 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AOQ81_23440 ENOG4105C2M dna polymerase I AOQ81_23445 ENOG4105BZU Histidine kinase AOQ81_23450 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_23470 ENOG4108HMX isocitrate dehydrogenase (NADP) AOQ81_23475 ENOG4105BZN citrate synthase AOQ81_23490 ENOG4108REF Sporulation integral membrane protein ytvi AOQ81_23495 ENOG4105FS0 cytoplasmic membrane protein AOQ81_23520 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family AOQ81_23525 ENOG4105C6K Malic enzyme AOQ81_23530 ENOG4105C0B DNA polymerase III (alpha subunit) AOQ81_23535 ENOG4105VV2 AOQ81_23545 ENOG4105SFS phosphoesterase RecJ domain protein AOQ81_23580 ENOG4105DC7 peptidase M24 AOQ81_23615 ENOG4105Z7P Acetyltransferase (GNAT) family AOQ81_23620 ENOG41082W1 Cupin 2, conserved barrel domain protein AOQ81_23630 ENOG4105VZ8 Transcriptional regulator AOQ81_23650 ENOG4107YZX Universal stress protein AOQ81_23690 ENOG4108JYZ YitT family AOQ81_23710 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AOQ81_23720 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AOQ81_23725 ENOG4105KBJ sporulation protein ytfj AOQ81_23740 ENOG4105EFZ amidohydrolase AOQ81_23750 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AOQ81_23775 ENOG4106KR7 LysR family Transcriptional regulator AOQ81_23795 ENOG4105C28 cystathionine AOQ81_23815 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AOQ81_23825 ENOG4105EMN RNA polymerase sigma factor AOQ81_23840 ENOG4105F1V Acetoin utilization protein AOQ81_23845 ENOG4105W87 Cbs domain AOQ81_23850 ENOG4105DGU Histone deacetylase AOQ81_23860 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AOQ81_23870 ENOG4107SNB ankyrin repeat protein YahD AOQ81_23875 ENOG4105EP9 oxidoreductase AOQ81_23905 ENOG4105ETE Transcriptional regulator (LacI family AOQ81_23930 ENOG4105C88 aminopeptidase AOQ81_23975 ENOG4108VDD TRNA binding domain protein AOQ81_24005 ENOG4105C8F Beta-lactamase domain protein AOQ81_24020 ENOG4108V15 phosphotransferase enzyme family AOQ81_24025 ENOG4108IUM Glycogen debranching enzyme AOQ81_24040 ENOG4107QSE Dipeptidase AOQ81_24045 ENOG4107QSE Dipeptidase AOQ81_24050 ENOG4105YW5 deoR family transcriptional regulator AOQ81_24065 ENOG4105CBX hi0933 family AOQ81_24100 ENOG4108VJ1 Transcriptional regulator (CarD family AOQ81_24105 ENOG4107EXU Short-chain dehydrogenase reductase Sdr AOQ81_24110 ENOG4105CSC Glucose uptake protein AOQ81_24125 ENOG4108ZAF Molybdopterin AOQ81_24130 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein AOQ81_24135 ENOG4105CVM Molybdenum cofactor synthesis domain protein AOQ81_24145 ENOG4105D06 uba thif-type nad fad binding protein AOQ81_24170 ENOG41085GJ domain protein AOQ81_24180 ENOG4105DWV Homoserine O-trans-acetylase AOQ81_24190 ENOG4108B31 Spore germination protein AOQ81_24225 ENOG410605W Major Facilitator AOQ81_24230 ENOG4107S91 Sodium hydrogen exchanger AOQ81_24235 ENOG4105NCW Trka-c domain protein AOQ81_24250 ENOG4105C19 ABC transporter AOQ81_24270 ENOG4105N5T Radical SAM Protein AOQ81_24280 ENOG4105DA5 (ABC) transporter AOQ81_24310 ENOG4105E8V Alpha Beta Hydrolase Fold protein AOQ81_24315 ENOG4108Z0R Transferase AOQ81_24320 ENOG4105YVM Phosphoesterase, PA-phosphatase related AOQ81_24325 ENOG4105BZF Glycosyl transferase (Group 1 AOQ81_24335 ENOG4108RIR Molybdenum cofactor biosynthesis protein AOQ81_24390 ENOG4105EGD dinuclear metal center protein, YbgI family AOQ81_24395 ENOG4105BZU Histidine kinase AOQ81_24400 ENOG4105BZU Histidine kinase AOQ81_24405 ENOG4107S9D Alpha beta hydrolase AOQ81_24425 ENOG4105D2X ABC transporter substrate-binding protein AOQ81_24435 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component AOQ81_24490 ENOG4108V2W Carbonate dehydratase AOQ81_24495 ENOG4105C4M (Ubiquinol oxidase) subunit I AOQ81_24500 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AOQ81_24545 ENOG41087YS Phage shock protein A AOQ81_24580 ENOG4105BZU Histidine kinase AOQ81_24585 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_24610 ENOG4108UGV hypoxanthine phosphoribosyltransferase AOQ81_24615 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) AOQ81_24650 ENOG4107ZTW SNARE associated Golgi AOQ81_24665 ENOG4105C19 ABC transporter AOQ81_24670 ENOG41086D8 Transcriptional regulator AOQ81_24720 ENOG4105C6Z Gluconate AOQ81_24725 ENOG4105FDP GntR family transcriptional regulator AOQ81_24745 ENOG41069H0 dihydroorotase EC 3.5.2.3 AOQ81_24775 ENOG4105DTQ mandelate racemase muconate lactonizing AOQ81_24785 ENOG4108IPT Naphthoate synthase AOQ81_24790 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) AOQ81_24795 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AOQ81_24800 ENOG4105E4F Isochorismate synthase AOQ81_24805 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AOQ81_24815 ENOG4105VEQ Cold shock protein AOQ81_24840 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AOQ81_24850 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) AOQ81_24860 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOQ81_24955 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AOQ81_24990 ENOG4105KT7 mgtC SapB transporter AOQ81_24995 ENOG4107PBV potassium channel AOQ81_25005 ENOG4107QYV phosphohexose isomerase AOQ81_25015 ENOG4105WG9 Conserved Protein AOQ81_25025 ENOG4105CHM Aminotransferase AOQ81_25030 ENOG4108ZB6 transcriptional regulator AsnC family AOQ81_25035 ENOG4105C5I Dehydrogenase AOQ81_25040 ENOG4108MUZ hydrolase AOQ81_25050 ENOG4105C87 Aminotransferase class I and II AOQ81_25065 ENOG4105Y38 Kinase-associated protein B AOQ81_25075 ENOG4107R3E Citrate transporter AOQ81_25090 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) AOQ81_25095 ENOG4105KA0 thioesterase Superfamily protein AOQ81_25115 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AOQ81_25135 ENOG41069ER domain protein AOQ81_25150 ENOG4105CEP NADH dehydrogenase AOQ81_25180 ENOG4105EWC Purine nucleoside phosphorylase AOQ81_25200 ENOG4108YX9 iron--sulfur cluster insertion protein erpA AOQ81_25225 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AOQ81_25230 ENOG4105C4B ABC transporter, permease AOQ81_25235 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AOQ81_25280 ENOG41083MR nifu domain-containing protein AOQ81_25295 ENOG4108W5N phosphatidylglycerophosphatase a AOQ81_25310 ENOG4105DYS nad(p)h dehydrogenase (quinone) AOQ81_25315 ENOG4105D4U had-superfamily hydrolase, subfamily iia AOQ81_25330 ENOG4105CBT Fructose-1,6-bisphosphatase AOQ81_25350 ENOG4105MMD transcriptional regulator AOQ81_25355 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AOQ81_25360 ENOG4107TXC Transcriptional regulator AOQ81_25365 ENOG41090T1 Membrane AOQ81_25390 ENOG4105FAA peptidase M23 AOQ81_25400 ENOG4105KZD Domain of unknown function (DUF1805) AOQ81_25405 ENOG4107R8B 5'-nucleotidase AOQ81_25430 ENOG4105DIW FeS assembly protein SUFB AOQ81_25435 ENOG4108UNV SUF system FeS assembly protein, NifU family AOQ81_25440 ENOG4105C9B Cysteine desulfurase AOQ81_25445 ENOG4105JRK feS assembly protein SufD AOQ81_25450 ENOG4105C3K feS assembly ATPase SufC AOQ81_25455 ENOG4105D01 (LipO)protein AOQ81_25460 ENOG4105D01 (LipO)protein AOQ81_25465 ENOG4108UMI ABC transporter, permease AOQ81_25500 ENOG41080E8 Transcriptional regulator, Spx MgsR family AOQ81_25550 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AOQ81_25575 ENOG4108W8B Beta-lactamase domain protein AOQ81_25580 ENOG4105C1G acyl-Coa dehydrogenase AOQ81_25590 ENOG4105CHU acetyl-coa acetyltransferase AOQ81_25605 ENOG4105DZ1 carboxypeptidase AOQ81_25625 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer AOQ81_25645 ENOG4108SUT Major Facilitator Superfamily AOQ81_25650 ENOG4107R7I amino acid AOQ81_25660 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AOQ81_25670 ENOG4107AYK membrAne AOQ81_25705 ENOG4107ZTW SNARE associated Golgi AOQ81_25715 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AOQ81_25720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_25725 ENOG4105BZU Histidine kinase AOQ81_25735 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AOQ81_25750 ENOG4105VG1 fes assembly suf system protein AOQ81_25755 ENOG4105D4Y metalloprotease AOQ81_25775 ENOG4107S91 Sodium hydrogen exchanger AOQ81_25780 ENOG4105NCW Trka-c domain protein AOQ81_25795 ENOG4108RMU ferritin dps family protein AOQ81_25810 ENOG4108URH decarboxylase AOQ81_25835 ENOG4105D9N nucleoside AOQ81_25840 ENOG4105D9N nucleoside AOQ81_25855 ENOG4108RYK Nad-dependent epimerase dehydratase AOQ81_25870 ENOG4105CV8 reductase AOQ81_25875 ENOG4105F27 Major Facilitator AOQ81_25880 ENOG4105KVH Transcriptional regulator AOQ81_25895 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AOQ81_25900 ENOG4105D4A Cell wall formation (By similarity) AOQ81_25910 ENOG4105C8Q Methyl-accepting chemotaxis AOQ81_25920 ENOG4105WMR Protein CrcB homolog AOQ81_25925 ENOG4105WMR Protein CrcB homolog AOQ81_25940 ENOG4108MK9 spermidine N(1)-acetyltransferase AOQ81_25945 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AOQ81_25960 ENOG4108IPW abc transporter atp-binding protein AOQ81_25965 ENOG4105CM4 permease protein AOQ81_25990 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AOQ81_26000 ENOG4105XZU Preprotein translocase, subunit SecG AOQ81_26005 ENOG41067MG lrgb family AOQ81_26105 ENOG4105EFC phage portal protein HK97 family AOQ81_26130 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AOQ81_26140 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AOQ81_26145 ENOG4105CP7 Triose-phosphate isomerase AOQ81_26170 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_26190 ENOG41090VF Stage v sporulation protein ac AOQ81_26195 ENOG4105CZ3 stage V sporulation protein ad AOQ81_26210 ENOG4105H67 Protein of unknown function (DUF421) AOQ81_26215 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AOQ81_26220 ENOG4105KRI phosphocarrier protein (HPr AOQ81_26230 ENOG4105CHW UPF0052 protein AOQ81_26240 ENOG4108Z4K mutator MutT protein AOQ81_26250 ENOG4105C3M thioredoxin reductase AOQ81_26260 ENOG4108S4C acetyltransferase AOQ81_26280 ENOG41086DT Membrane protein of unknown function AOQ81_26290 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AOQ81_26295 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AOQ81_26300 ENOG4105D7V transposase AOQ81_26315 ENOG4107TXC Transcriptional regulator AOQ81_26340 ENOG4105HMI Membrane AOQ81_26345 ENOG4105DUM transcriptional regulator, lysR family AOQ81_26355 ENOG4108WS4 fmn reductase AOQ81_26370 ENOG4105BZ1 (ABC) transporter AOQ81_26380 ENOG4105CN1 protease AOQ81_26385 ENOG4105CRP Part of the ABC transporter FtsEX involved in AOQ81_26390 ENOG4105CAK Cell division ATP-binding protein ftsE AOQ81_26405 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) AOQ81_26410 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving AOQ81_26415 ENOG4105MS2 ribosomal subunit Interface protein AOQ81_26420 ENOG4105VEQ Cold shock protein AOQ81_26425 ENOG41081UC Inherit from COG: Competence protein AOQ81_26440 ENOG4105KVH Transcriptional regulator AOQ81_26455 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AOQ81_26460 ENOG4108KGH TRANSCRIPTIONal AOQ81_26465 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AOQ81_26470 ENOG4105C6Y Udp-glucose 6-dehydrogenase AOQ81_26475 ENOG4105ESV Glycosyl transferase, family 4 AOQ81_26485 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AOQ81_26500 ENOG410901P UPF0249 protein AOQ81_26505 ENOG4105F8D glycoside hydrolase family 4 AOQ81_26510 ENOG4105VCP PTS System AOQ81_26515 ENOG4105CK1 PTS System AOQ81_26525 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) AOQ81_26530 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AOQ81_26535 ENOG4105VCP PTS System AOQ81_26545 ENOG4105VZJ PTS System AOQ81_26560 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase AOQ81_26565 ENOG4105ECB domain protein AOQ81_26570 ENOG4107RSM transcriptional regulator AOQ81_26615 ENOG4105DAA L-lactate AOQ81_26625 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) AOQ81_26635 ENOG4105E0M Sulfatase AOQ81_26670 ENOG4105C94 Transporter AOQ81_26675 ENOG41069ER domain protein AOQ81_26700 ENOG4105KBK Zinc finger, swim domain protein AOQ81_26705 ENOG4105C0D helicase AOQ81_26735 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AOQ81_26745 ENOG4107RBB ABC transporter, permease AOQ81_26750 ENOG4105C19 ABC transporter AOQ81_26770 ENOG4105CXY transporter AOQ81_26785 ENOG4105BZU Histidine kinase AOQ81_26790 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_26795 ENOG4105CMR udp-glucose 4-epimerase AOQ81_26810 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AOQ81_26815 ENOG4105EY8 ABC transporter AOQ81_26870 ENOG4105MT0 Sporulation transcriptional regulator spoiiid AOQ81_26885 ENOG4105FRN stage II sporulation protein AOQ81_26900 ENOG4105DY9 regulatoR AOQ81_26905 ENOG4108IUW ABC transporter AOQ81_26925 ENOG4106778 Protein of unknown function (DUF1146) AOQ81_26930 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AOQ81_26935 ENOG4105C8S subunit m AOQ81_26940 ENOG4105D65 subunit l AOQ81_26965 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AOQ81_26970 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AOQ81_26980 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain AOQ81_26985 ENOG4105BZU Histidine kinase AOQ81_27035 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) AOQ81_27040 ENOG41062M3 atp synthase AOQ81_27070 ENOG4108YZG isomerase AOQ81_27085 ENOG4108VGI doxx family AOQ81_27090 ENOG4107XC4 flavin reductase domain protein, FMN-binding AOQ81_27105 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AOQ81_27115 ENOG4108ZXQ stage ii sporulation protein r AOQ81_27120 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AOQ81_27125 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) AOQ81_27140 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AOQ81_27145 ENOG4105CBT Fructose-1,6-bisphosphatase AOQ81_27150 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AOQ81_27185 ENOG4105C1G acyl-Coa dehydrogenase AOQ81_27190 ENOG4105C1G acyl-Coa dehydrogenase AOQ81_27195 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AOQ81_27205 ENOG4105DF6 Fe-S oxidoreductase AOQ81_27220 ENOG4105BZU Histidine kinase AOQ81_27240 ENOG4105BZU Histidine kinase AOQ81_27245 ENOG4105KCT ABC transporter AOQ81_27250 ENOG4108M15 ABC transporter AOQ81_27255 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) AOQ81_27275 ENOG4105IIU Aminopeptidase AOQ81_27295 ENOG4105EMN RNA polymerase sigma factor AOQ81_27305 ENOG410684U Domain of unknown function (DUF1934) AOQ81_27330 ENOG4105CYW agmatinase AOQ81_27340 ENOG4105DXB Major Facilitator superfamily AOQ81_27345 ENOG4107SWG transcriptional regulator MERR family AOQ81_27350 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AOQ81_27355 ENOG4105BZ4 penicillin-binding protein AOQ81_27360 ENOG4108XFG YwhD family AOQ81_27365 ENOG4108Z4T Peptidase M50 AOQ81_27370 ENOG41069HH 4-oxalocrotonate tautomerase AOQ81_27375 ENOG4105DCI Phosphohydrolase AOQ81_27380 ENOG4108MES Periplasmic binding protein AOQ81_27385 ENOG4105E0A ABC, transporter AOQ81_27390 ENOG4105EHG Permease protein AOQ81_27395 ENOG4105DQ5 transport system permease protein AOQ81_27400 ENOG4105DQ5 transport system permease protein AOQ81_27410 ENOG4108VCI transcription factor, rsfa family AOQ81_27425 ENOG4108IJ2 phosphate acetyltransferase AOQ81_27440 ENOG4108VKI Cell wall hydrolase AOQ81_27470 ENOG410667J hydrolase AOQ81_27475 ENOG4105VCH membrane AOQ81_27485 ENOG4108TU7 Inherit from COG: (ABC) transporter AOQ81_27490 ENOG4105CJ1 ABC, transporter AOQ81_27495 ENOG41090WU lipolytic protein G-D-S-L family AOQ81_27510 ENOG4105D6E homoserine dehydrogenase AOQ81_27535 ENOG4108Y4K DNA-binding transcriptional activator AOQ81_27545 ENOG4105WH1 Two component transcriptional regulator luxr family AOQ81_27555 ENOG4105DWF phosphomethylpyrimidine kinase AOQ81_27560 ENOG4105BZU Histidine kinase AOQ81_27565 ENOG4105VCD cytoplasmic protein AOQ81_27570 ENOG4105D22 carbon starvation protein AOQ81_27575 ENOG4105DY9 regulatoR AOQ81_27580 ENOG41079KZ Major Facilitator Superfamily AOQ81_27600 ENOG4105EN6 Membrane AOQ81_27605 ENOG4106YBV Methyl-accepting chemotaxis AOQ81_27615 ENOG4108S4H thioesterase Superfamily protein AOQ81_27625 ENOG4105JEU Glycosyl transferase, family 2 AOQ81_27630 ENOG4105C5H ABC transporter AOQ81_27660 ENOG4105CKK Glycosyl transferase, family 2 AOQ81_27665 ENOG41067SE Tetr family transcriptional regulator AOQ81_27675 ENOG4105E0X reductase AOQ81_27680 ENOG4106F5Q Membrane AOQ81_27695 ENOG4105DY9 regulatoR AOQ81_27700 ENOG4108HRK Histidine kinase AOQ81_27705 ENOG4107RGD Major Facilitator superfamily AOQ81_27720 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AOQ81_27730 ENOG4105IW1 AmiS UreI transporter AOQ81_27740 ENOG4105CMR udp-glucose 4-epimerase AOQ81_27745 ENOG4108UT2 hemolysin iii AOQ81_27755 ENOG4105C1J atp-dependent rna helicase AOQ81_27770 ENOG4105DPN Oligoendopeptidase f AOQ81_27790 ENOG4105C0H protease AOQ81_27795 ENOG4105Q2H domain protein AOQ81_27810 ENOG4105BZU Histidine kinase AOQ81_27815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AOQ81_27845 ENOG4105CDU Replicative dna helicase AOQ81_27855 ENOG4105BZR domain protein AOQ81_27860 ENOG4108XMW Membrane AOQ81_27870 ENOG4108UUM single-stranded DNA-binding protein AOQ81_27880 ENOG4105C3G gtp-binding protein AOQ81_27885 ENOG4105VDK protein, conserved in bacteria AOQ81_27890 ENOG4105D8X mechanosensitive ion channel AOQ81_27895 ENOG4108ZDA Sporulation protein YyaC AOQ81_27900 ENOG4105FA0 parb-like partition protein AOQ81_27905 ENOG4107QJE Chromosome Partitioning Protein AOQ81_27925 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AOQ81_27935 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins