locus-tag	class	description
BF90_10	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF90_1002	COG0443	Heat shock 70 kDa protein
BF90_1005	COG1522	sequence-specific DNA binding
BF90_1009	COG0346	lactoylglutathione lyase activity
BF90_101	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_1013	COG2169	Transcriptional regulator
BF90_102	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF90_1020	COG2814	Major facilitator Superfamily
BF90_1025	COG0745	RESPONSE REGULATOR receiver
BF90_1026	COG3850	Histidine kinase
BF90_1026	COG5002	protein histidine kinase activity
BF90_1031	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF90_1037	COG1476	TRANSCRIPTIONal
BF90_1040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_1041	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF90_1043	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_1044	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF90_1047	COG1136	(ABC) transporter
BF90_1048	COG0577	efflux transmembrane transporter activity
BF90_1051	COG3850	Histidine kinase
BF90_1051	COG5002	protein histidine kinase activity
BF90_1053	COG2364	Membrane
BF90_1054	COG1846	Transcriptional regulator
BF90_1055	COG0456	acetyltransferase
BF90_1056	COG2808	Putative FMN-binding domain
BF90_1057	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_1058	COG2271	Major facilitator Superfamily
BF90_1059	COG1556	Lactate utilization protein
BF90_106	COG1335	isochorismatase
BF90_1060	COG1139	Iron-sulfur cluster binding protein
BF90_1062	COG0583	DNA-binding transcription factor activity
BF90_1064	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF90_1068	COG0738	Major facilitator superfamily
BF90_1069	COG0673	inositol 2-dehydrogenase activity
BF90_107	COG1051	belongs to the nudix hydrolase family
BF90_1070	COG0561	phosphatase activity
BF90_1071	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF90_1072	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF90_1073	COG1609	Transcriptional regulator
BF90_1074	COG0457	Tetratricopeptide repeat
BF90_1078	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF90_1085	COG0534	Mate efflux family protein
BF90_1088	COG2184	nucleotidyltransferase activity
BF90_1089	COG2814	Major facilitator Superfamily
BF90_109	COG0668	transmembrane transport
BF90_1090	COG1309	transcriptional regulator
BF90_1093	COG0814	amino acid
BF90_1094	COG1760	l-serine dehydratase
BF90_1095	COG1760	l-serine dehydratase
BF90_1096	COG1760	l-serine dehydratase
BF90_1097	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF90_1098	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF90_110	COG4585	Histidine kinase
BF90_110	COG2203	Gaf domain
BF90_1102	COG1522	sequence-specific DNA binding
BF90_1103	COG0531	amino acid
BF90_1106	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF90_111	COG2197	response regulator
BF90_1110	COG1595	DNA-templated transcription, initiation
BF90_1113	COG0662	Cupin 2, conserved barrel domain protein
BF90_1114	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_1114	COG2207	Transcriptional regulator
BF90_1125	COG0477	Major facilitator Superfamily
BF90_1127	COG1846	Transcriptional regulator
BF90_1128	COG2814	Major facilitator Superfamily
BF90_113	COG1737	Transcriptional regulator
BF90_1131	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF90_1132	COG1131	(ABC) transporter
BF90_1136	COG2076	Multidrug Resistance protein
BF90_1137	COG1309	transcriptional regulator
BF90_1139	COG2031	fatty acid transporter
BF90_114	COG1064	alcohol dehydrogenase
BF90_1141	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF90_1148	COG1122	ATPase activity
BF90_1149	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF90_1153	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF90_1154	COG1288	antiporter activity
BF90_1155	COG2356	endonuclease I
BF90_1158	COG3620	sequence-specific DNA binding
BF90_1159	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF90_1160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF90_1161	COG0124	histidyl-tRNA synthetase
BF90_1164	COG1733	regulation of RNA biosynthetic process
BF90_1165	COG0778	Nitroreductase
BF90_1169	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1171	COG1131	(ABC) transporter
BF90_1176	COG1011	Hydrolase
BF90_1183	COG0346	lactoylglutathione lyase activity
BF90_1184	COG1940	carbohydrate kinase activity
BF90_1185	COG0738	Major facilitator superfamily
BF90_1186	COG0110	maltose O-acetyltransferase activity
BF90_1188	COG1136	(ABC) transporter
BF90_1190	COG0180	Tryptophanyl-tRNA synthetase
BF90_1191	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF90_1192	COG0628	permease
BF90_1196	COG2226	methyltransferase
BF90_1198	COG0477	Major facilitator Superfamily
BF90_120	COG1070	Carbohydrate kinase
BF90_1204	COG1253	flavin adenine dinucleotide binding
BF90_1205	COG0789	Transcriptional regulator
BF90_1206	COG0697	spore germination
BF90_1207	COG1357	PFAM Pentapeptide repeats (8 copies)
BF90_1208	COG3813	Protein conserved in bacteria
BF90_1209	COG2706	6-phosphogluconolactonase activity
BF90_1210	COG1070	Carbohydrate kinase
BF90_1212	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF90_1213	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF90_1215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF90_1216	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF90_1217	COG0604	alcohol dehydrogenase
BF90_1218	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF90_1221	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1226	COG0656	L-ascorbic acid biosynthetic process
BF90_1227	COG2814	Major facilitator Superfamily
BF90_1230	COG0346	lactoylglutathione lyase activity
BF90_1231	COG0814	amino acid
BF90_1236	COG1393	Belongs to the ArsC family
BF90_1237	COG1733	regulation of RNA biosynthetic process
BF90_1238	COG2188	Transcriptional regulator
BF90_1239	COG0673	inositol 2-dehydrogenase activity
BF90_1240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF90_1241	COG1733	regulation of RNA biosynthetic process
BF90_1242	COG1733	regulation of RNA biosynthetic process
BF90_1245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_1249	COG0384	phenazine biosynthesis protein PhzF
BF90_1251	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1253	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_1255	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF90_1256	COG1733	regulation of RNA biosynthetic process
BF90_1260	COG0726	polysaccharide deacetylase
BF90_1263	COG1191	sigma factor activity
BF90_1266	COG1309	transcriptional regulator
BF90_127	COG1125	glycine betaine transport
BF90_127	COG0517	IMP dehydrogenase activity
BF90_1270	COG3152	Membrane
BF90_1275	COG1151	hydroxylamine reductase activity
BF90_1278	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_1279	COG3409	Peptidoglycan-binding domain 1 protein
BF90_1279	COG3757	hydrolase, family 25
BF90_128	COG1174	glycine betaine transport
BF90_1286	COG2072	flavoprotein involved in K transport
BF90_1294	COG0604	alcohol dehydrogenase
BF90_1295	COG1113	amino acid transport
BF90_1296	COG2814	Major facilitator Superfamily
BF90_13	COG1418	mRNA catabolic process
BF90_1302	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF90_1303	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF90_1307	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_1309	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_1310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_1311	COG3739	integral membrane protein
BF90_1312	COG0384	phenazine biosynthesis protein PhzF
BF90_1318	COG0583	DNA-binding transcription factor activity
BF90_1322	COG1193	negative regulation of DNA recombination
BF90_1326	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF90_1327	COG1164	Oligoendopeptidase f
BF90_1328	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF90_1335	COG0584	glycerophosphoryl diester phosphodiesterase
BF90_1339	COG0640	Transcriptional regulator
BF90_1340	COG0604	alcohol dehydrogenase
BF90_1342	COG0457	Tetratricopeptide repeat
BF90_1345	COG2808	Putative FMN-binding domain
BF90_1347	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF90_1349	COG0385	Bile acid
BF90_135	COG1253	flavin adenine dinucleotide binding
BF90_1350	COG0277	FAD linked oxidase domain protein
BF90_1356	COG1216	Glycosyl transferase, family 2
BF90_1357	COG1024	Enoyl-CoA hydratase
BF90_1359	COG1285	pathogenesis
BF90_136	COG1012	belongs to the aldehyde dehydrogenase family
BF90_1361	COG2514	catechol 2,3-dioxygenase activity
BF90_1362	COG2720	vancomycin resistance protein
BF90_1368	COG1278	Cold shock
BF90_137	COG5506	Protein of unknown function (DUF1694)
BF90_1370	COG0716	FMN binding
BF90_1376	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1378	COG0165	Argininosuccinate lyase
BF90_1382	COG4145	pantothenate transmembrane transporter activity
BF90_1384	COG1012	belongs to the aldehyde dehydrogenase family
BF90_1385	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1387	COG1657	PFAM Prenyltransferase squalene oxidase
BF90_1388	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF90_1389	COG2962	Rard protein
BF90_1390	COG3326	Membrane
BF90_1393	COG0489	protein tyrosine kinase activity
BF90_1395	COG0314	molybdopterin synthase activity
BF90_1396	COG0303	'Molybdopterin
BF90_1397	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF90_1398	COG2116	formate transmembrane transporter activity
BF90_14	COG0488	(ABC) transporter
BF90_140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF90_1400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF90_1401	COG5609	conserved protein (DUF2294)
BF90_1402	COG2427	Protein of unknown function (DUF1641)
BF90_1403	COG3383	formate dehydrogenase (NAD+) activity
BF90_1405	COG0697	spore germination
BF90_141	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF90_1414	COG2226	methyltransferase
BF90_1415	COG4166	transmembrane transport
BF90_1416	COG4166	transmembrane transport
BF90_1417	COG1301	dicarboxylic acid transport
BF90_1418	COG1316	TRANSCRIPTIONal
BF90_142	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF90_1420	COG1595	DNA-templated transcription, initiation
BF90_1424	COG1131	(ABC) transporter
BF90_1426	COG0673	inositol 2-dehydrogenase activity
BF90_1427	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF90_1428	COG0187	DNA topoisomerase II activity
BF90_1429	COG1832	CoA-binding protein
BF90_143	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF90_1430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF90_1431	COG0745	RESPONSE REGULATOR receiver
BF90_1434	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF90_1435	COG4841	protein insertion into membrane
BF90_1436	COG0824	Thioesterase
BF90_144	COG0456	acetyltransferase
BF90_1442	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF90_1444	COG2274	protein secretion by the type I secretion system
BF90_1445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF90_1447	COG0726	polysaccharide deacetylase
BF90_145	COG3829	transcription factor binding
BF90_1450	COG2211	Major facilitator Superfamily
BF90_1452	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF90_1455	COG0183	Belongs to the thiolase family
BF90_1456	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_1457	COG1268	BioY protein
BF90_1458	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_146	COG1509	lysine 2,3-aminomutase activity
BF90_1467	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_1469	COG5002	protein histidine kinase activity
BF90_1470	COG0400	carboxylic ester hydrolase activity
BF90_1471	COG0346	lactoylglutathione lyase activity
BF90_1472	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF90_1473	COG0069	glutamate synthase activity
BF90_1474	COG1902	pentaerythritol trinitrate reductase activity
BF90_1475	COG1329	Transcriptional regulator
BF90_1476	COG0010	Belongs to the arginase family
BF90_1481	COG2226	methyltransferase
BF90_1491	COG4846	Membrane protein involved in cytochrome C biogenesis
BF90_1492	COG0785	Cytochrome C biogenesis protein
BF90_1494	COG0583	DNA-binding transcription factor activity
BF90_1495	COG1380	Effector of murein hydrolase LrgA
BF90_1496	COG1346	cytolysis
BF90_1500	COG0730	response to heat
BF90_1502	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF90_1502	COG3409	Peptidoglycan-binding domain 1 protein
BF90_1505	COG1132	(ABC) transporter
BF90_1506	COG1132	(ABC) transporter
BF90_1512	COG3639	organic phosphonate transmembrane transporter activity
BF90_1513	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF90_1516	COG0737	Belongs to the 5'-nucleotidase family
BF90_1518	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF90_1522	COG1695	Transcriptional regulator
BF90_1530	COG1388	LysM domain
BF90_1530	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF90_1530	COG3409	Peptidoglycan-binding domain 1 protein
BF90_1531	COG4824	toxin secretion phage lysis holin
BF90_154	COG4326	sporulation control protein
BF90_155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF90_156	COG0671	phosphoesterase, PA-phosphatase related
BF90_1563	COG1595	DNA-templated transcription, initiation
BF90_157	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF90_1571	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF90_1587	COG1396	sequence-specific DNA binding
BF90_1592	COG0174	glutamine synthetase
BF90_1593	COG0789	Transcriptional regulator
BF90_1594	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF90_1595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF90_1596	COG2860	membrane
BF90_1598	COG0464	growth
BF90_1604	COG1388	LysM domain
BF90_1604	COG3584	3D domain protein
BF90_1605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF90_1605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF90_1605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF90_1606	COG1105	Belongs to the carbohydrate kinase PfkB family
BF90_1607	COG1349	DNA-binding transcription factor activity
BF90_1608	COG1979	alcohol dehydrogenase
BF90_1609	COG1979	alcohol dehydrogenase
BF90_1610	COG2322	membrane
BF90_1613	COG1113	amino acid transport
BF90_1617	COG1408	metallophosphoesterase
BF90_1618	COG2116	formate transmembrane transporter activity
BF90_162	COG1787	Restriction endonuclease
BF90_162	COG1715	Restriction endonuclease
BF90_1620	COG2217	Heavy metal translocating P-type atpase
BF90_1621	COG2608	mercury ion transmembrane transporter activity
BF90_1622	COG1937	Protein conserved in bacteria
BF90_1624	COG2819	hydrolase of the alpha beta superfamily
BF90_1625	COG1120	ATPase activity
BF90_1626	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_1627	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_1628	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_1630	COG0708	Exodeoxyribonuclease III
BF90_1631	COG0708	Exodeoxyribonuclease III
BF90_1632	COG2169	Transcriptional regulator
BF90_1633	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF90_1634	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF90_1636	COG2364	Membrane
BF90_1640	COG2267	carboxylic ester hydrolase activity
BF90_1641	COG0346	lactoylglutathione lyase activity
BF90_1643	COG3300	MHYT domain
BF90_1643	COG5001	Diguanylate cyclase
BF90_1646	COG1346	cytolysis
BF90_1647	COG1380	Effector of murein hydrolase LrgA
BF90_1648	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_1649	COG0596	Alpha beta hydrolase
BF90_1649	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF90_1650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF90_1653	COG1404	Belongs to the peptidase S8 family
BF90_1654	COG3773	Cell wall hydrolase
BF90_1655	COG0562	UDP-galactopyranose mutase
BF90_1656	COG1368	sulfuric ester hydrolase activity
BF90_1657	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF90_1659	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF90_1668	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF90_1669	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF90_1670	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF90_1671	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF90_1671	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF90_1673	COG2359	stage V sporulation protein S
BF90_1674	COG1692	metallophosphoesterase
BF90_1679	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF90_1680	COG1426	Protein conserved in bacteria
BF90_1683	COG0300	oxidoreductase activity
BF90_1684	COG0612	Peptidase, M16
BF90_1685	COG0612	Peptidase, M16
BF90_1691	COG2188	Transcriptional regulator
BF90_1692	COG1674	ftsk spoiiie
BF90_1694	COG0740	serine-type endopeptidase activity
BF90_1695	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF90_1697	COG0527	aspartate kinase activity
BF90_1698	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF90_1699	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF90_17	COG0629	single-stranded DNA binding
BF90_1700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF90_1701	COG1873	PFAM PRC-barrel domain
BF90_1702	COG0612	Peptidase, M16
BF90_1703	COG0726	polysaccharide deacetylase
BF90_1706	COG0196	riboflavin kinase activity
BF90_1707	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF90_1709	COG1550	Protein conserved in bacteria
BF90_1711	COG1358	cellular component organization or biogenesis
BF90_1712	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF90_1713	COG0195	Participates in both transcription termination and antitermination
BF90_1717	COG0750	zinc metalloprotease
BF90_1718	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF90_1719	COG4589	Belongs to the CDS family
BF90_1722	COG0528	UMP kinase activity
BF90_1728	COG4974	Belongs to the 'phage' integrase family
BF90_1730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF90_1732	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF90_1740	COG1837	Belongs to the UPF0109 family
BF90_1742	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF90_1744	COG0552	protein localization to endoplasmic reticulum
BF90_1745	COG1196	nuclear chromosome segregation
BF90_1748	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1749	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF90_1752	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF90_1753	COG1461	Dihydroxyacetone kinase
BF90_1754	COG1302	Protein conserved in bacteria
BF90_1756	COG1564	THIamine pyrophosphokinase
BF90_1757	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF90_1758	COG1162	GTPase activity
BF90_1759	COG2815	serine threonine protein kinase
BF90_1759	COG0515	serine threonine protein kinase
BF90_1760	COG0631	protein serine/threonine phosphatase activity
BF90_1762	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF90_1762	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF90_1764	COG0242	peptide deformylase activity
BF90_1765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF90_1766	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF90_1768	COG0194	GDP metabolic process
BF90_1770	COG1561	YicC-like family, N-terminal region
BF90_1771	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF90_1773	COG0006	proline dipeptidase activity
BF90_1776	COG3069	C4-dicarboxylate transmembrane transporter activity
BF90_178	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF90_1784	COG0505	Belongs to the CarA family
BF90_1789	COG0564	pseudouridine synthase activity
BF90_1792	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF90_1793	COG3599	regulation of cell shape
BF90_1794	COG2302	S4 RNA-binding domain
BF90_1795	COG0762	integral membrane protein
BF90_1797	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF90_1799	COG1873	PFAM PRC-barrel domain
BF90_1800	COG1191	sigma factor activity
BF90_1801	COG1191	sigma factor activity
BF90_1803	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF90_1804	COG0849	cell division
BF90_1805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF90_1806	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF90_1807	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF90_1808	COG0772	Belongs to the SEDS family
BF90_1811	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF90_1812	COG0768	penicillin binding
BF90_1814	COG4839	cell division protein FtsL
BF90_1817	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF90_1821	COG1399	metal-binding, possibly nucleic acid-binding protein
BF90_1831	COG4824	toxin secretion phage lysis holin
BF90_1851	COG4626	Terminase
BF90_1851	COG1802	Transcriptional regulator
BF90_1856	COG0582	viral genome integration into host DNA
BF90_186	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF90_186	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF90_187	COG2814	Major facilitator Superfamily
BF90_1871	COG1191	sigma factor activity
BF90_1876	COG1484	DNA-dependent DNA replication
BF90_188	COG4841	protein insertion into membrane
BF90_1881	COG1396	sequence-specific DNA binding
BF90_1885	COG1396	sequence-specific DNA binding
BF90_1889	COG0582	viral genome integration into host DNA
BF90_189	COG0372	Belongs to the citrate synthase family
BF90_1891	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF90_1892	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF90_1894	COG3314	Sporulation integral membrane protein YlbJ
BF90_1895	COG0742	ribosomal rna small subunit methyltransferase
BF90_1899	COG3679	Belongs to the UPF0342 family
BF90_190	COG2079	MmgE PrpD family protein
BF90_1900	COG0406	alpha-ribazole phosphatase activity
BF90_1903	COG2340	Cysteine-rich secretory protein family
BF90_1906	COG3336	cytochrome c oxidase
BF90_191	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF90_1913	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF90_1914	COG0772	Belongs to the SEDS family
BF90_1915	COG4838	Belongs to the UPF0358 family
BF90_1916	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF90_1917	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF90_1919	COG4896	Protein conserved in bacteria
BF90_192	COG1960	acyl-CoA dehydrogenase activity
BF90_1924	COG0483	inositol monophosphate 1-phosphatase activity
BF90_1928	COG1982	Orn Lys Arg decarboxylase major
BF90_193	COG2084	Dehydrogenase
BF90_1938	COG0022	dehydrogenase e1 component
BF90_1939	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF90_194	COG1012	belongs to the aldehyde dehydrogenase family
BF90_1941	COG0242	peptide deformylase activity
BF90_1942	COG0561	phosphatase activity
BF90_1944	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF90_1945	COG0569	domain protein
BF90_1949	COG0583	DNA-binding transcription factor activity
BF90_195	COG1280	lysine exporter protein (LysE YggA)
BF90_1950	COG0517	IMP dehydrogenase activity
BF90_1952	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF90_1954	COG4703	Protein of unknown function (DUF1797)
BF90_1957	COG2200	EAL domain
BF90_1958	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_1959	COG1408	metallophosphoesterase
BF90_196	COG1024	Enoyl-CoA hydratase
BF90_1961	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF90_1962	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF90_1969	COG2814	Major facilitator Superfamily
BF90_1973	COG3209	COG3209 Rhs family protein
BF90_1975	COG2205	protein histidine kinase activity
BF90_1977	COG0436	Aminotransferase
BF90_1978	COG1609	Transcriptional regulator
BF90_1979	COG3833	ABC-type maltose transport systems, permease component
BF90_1980	COG1175	transmembrane transport
BF90_1981	COG2182	Extracellular solute-binding protein
BF90_1983	COG0366	Alpha amylase catalytic
BF90_1984	COG3842	ATPase activity
BF90_199	COG0420	3'-5' exonuclease activity
BF90_1992	COG0183	Belongs to the thiolase family
BF90_1999	COG1695	Transcriptional regulator
BF90_20	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF90_200	COG0419	ATPase involved in DNA repair
BF90_2000	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_2004	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF90_2005	COG0436	Aminotransferase
BF90_2009	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF90_2012	COG2084	Dehydrogenase
BF90_2013	COG2084	Dehydrogenase
BF90_2014	COG3706	GGDEF domain
BF90_2015	COG0778	Nitroreductase
BF90_2020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_2020	COG1263	PTS System
BF90_2020	COG2190	(PTS) system
BF90_2021	COG3711	transcriptional antiterminator
BF90_2025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF90_2030	COG1547	Domain of unknown function (DUF309)
BF90_2031	COG0456	acetyltransferase
BF90_2032	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF90_2033	COG4086	secreted protein
BF90_2034	COG0561	phosphatase activity
BF90_2035	COG0697	spore germination
BF90_2038	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_204	COG2223	nitrite transmembrane transporter activity
BF90_2043	COG0733	neurotransmitter:sodium symporter activity
BF90_2047	COG1686	Belongs to the peptidase S11 family
BF90_2048	COG1725	Transcriptional regulator
BF90_2049	COG1131	(ABC) transporter
BF90_205	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_2052	COG1846	Transcriptional regulator
BF90_2055	COG0598	Magnesium transport protein CorA
BF90_206	COG1169	isochorismate synthase
BF90_2060	COG4974	Belongs to the 'phage' integrase family
BF90_2062	COG0735	belongs to the Fur family
BF90_2063	COG1300	Membrane
BF90_2067	COG0667	Aldo Keto reductase
BF90_2068	COG0656	L-ascorbic acid biosynthetic process
BF90_2069	COG0456	acetyltransferase
BF90_2069	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF90_207	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF90_2071	COG1525	nuclease
BF90_2071	COG4085	toxin activity
BF90_2071	COG0737	Belongs to the 5'-nucleotidase family
BF90_2073	COG0596	Alpha beta hydrolase
BF90_2074	COG2056	Na+-H+ antiporter family
BF90_2075	COG1609	Transcriptional regulator
BF90_2076	COG0456	acetyltransferase
BF90_2077	COG1073	alpha beta
BF90_208	COG1535	isochorismatase
BF90_208	COG3433	isochorismatase activity
BF90_2080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF90_2080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF90_2081	COG0307	riboflavin synthase, alpha
BF90_2085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF90_2086	COG4106	trans-aconitate 2-methyltransferase activity
BF90_2087	COG2226	methyltransferase
BF90_2087	COG1073	alpha beta
BF90_2088	COG0156	8-amino-7-oxononanoate synthase activity
BF90_209	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF90_2090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF90_2093	COG0737	Belongs to the 5'-nucleotidase family
BF90_2095	COG1522	sequence-specific DNA binding
BF90_2099	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF90_21	COG1413	lyase activity
BF90_210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF90_2101	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF90_2104	COG0300	oxidoreductase activity
BF90_2105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_2106	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF90_2107	COG1760	l-serine dehydratase
BF90_2108	COG1760	l-serine dehydratase
BF90_211	COG3251	PFAM MbtH domain protein
BF90_2111	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF90_2113	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF90_2114	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_2116	COG1376	ErfK ybiS ycfS ynhG family protein
BF90_2117	COG4129	membrane
BF90_2118	COG1126	abc transporter atp-binding protein
BF90_2119	COG0765	amino acid transport
BF90_212	COG2814	Major facilitator Superfamily
BF90_2120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF90_2123	COG2816	NAD+ diphosphatase activity
BF90_2124	COG0772	Belongs to the SEDS family
BF90_2125	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF90_2126	COG0022	dehydrogenase e1 component
BF90_2127	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF90_2128	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF90_2130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF90_2131	COG0280	phosphate acetyltransferase
BF90_2132	COG3290	protein histidine kinase activity
BF90_2132	COG3829	transcription factor binding
BF90_2134	COG0584	glycerophosphoryl diester phosphodiesterase
BF90_2135	COG3093	addiction module antidote protein HigA
BF90_2137	COG0745	RESPONSE REGULATOR receiver
BF90_2138	COG0750	zinc metalloprotease
BF90_2139	COG0497	DNA recombination
BF90_2141	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF90_2143	COG0142	geranyltranstransferase activity
BF90_2148	COG1302	Protein conserved in bacteria
BF90_2149	COG0439	Biotin carboxylase
BF90_215	COG0776	regulation of translation
BF90_2150	COG0511	ligase activity, forming carbon-carbon bonds
BF90_2159	COG3854	ATPases associated with a variety of cellular activities
BF90_2164	COG0006	proline dipeptidase activity
BF90_2167	COG3872	metal-dependent enzyme
BF90_2168	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF90_217	COG2318	DinB family
BF90_2173	COG0095	Lipoate-protein ligase
BF90_2174	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_2175	COG1609	Transcriptional regulator
BF90_2177	COG2076	Multidrug Resistance protein
BF90_2178	COG2076	Multidrug Resistance protein
BF90_2185	COG1131	(ABC) transporter
BF90_2186	COG1725	Transcriptional regulator
BF90_219	COG1115	amino acid carrier protein
BF90_2192	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF90_220	COG1115	amino acid carrier protein
BF90_2203	COG4970	Tfp pilus assembly protein FimT
BF90_2205	COG1459	type II secretion system
BF90_2206	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF90_2216	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF90_2217	COG0646	methionine synthase
BF90_2217	COG1410	methionine synthase
BF90_2218	COG0646	methionine synthase
BF90_2218	COG1410	methionine synthase
BF90_2219	COG0646	methionine synthase
BF90_2219	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF90_2220	COG0626	cystathionine gamma-synthase activity
BF90_2221	COG0626	cystathionine gamma-synthase activity
BF90_2225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_2227	COG1940	carbohydrate kinase activity
BF90_2228	COG4483	Protein conserved in bacteria
BF90_2229	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF90_223	COG2329	Antibiotic biosynthesis monooxygenase
BF90_2231	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF90_2232	COG0704	Plays a role in the regulation of phosphate uptake
BF90_2233	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF90_2234	COG0581	inorganic phosphate transmembrane transporter activity
BF90_2235	COG0573	inorganic phosphate transmembrane transporter activity
BF90_2236	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF90_2238	COG0477	Major facilitator Superfamily
BF90_2239	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF90_224	COG1187	pseudouridine synthase activity
BF90_2244	COG0735	belongs to the Fur family
BF90_2245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF90_2246	COG1121	(ABC) transporter
BF90_2247	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF90_2253	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF90_2254	COG2384	SAM-dependent methyltransferase
BF90_2255	COG2010	Cytochrome c
BF90_2256	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF90_2257	COG0358	DNA primase activity
BF90_2259	COG0517	IMP dehydrogenase activity
BF90_226	COG1136	(ABC) transporter
BF90_2262	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF90_2263	COG0295	cytidine deaminase activity
BF90_2264	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF90_2266	COG1480	7TM receptor with intracellular HD hydrolase
BF90_2267	COG1702	phosphate starvation-inducible protein PhoH
BF90_2270	COG1610	YqeY-like protein
BF90_2272	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF90_2273	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF90_2277	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF90_2279	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF90_2280	COG1733	regulation of RNA biosynthetic process
BF90_2285	COG1466	dna polymerase III delta subunit
BF90_2287	COG2333	competence protein COMEC
BF90_2287	COG0658	competence protein
BF90_2288	COG0658	competence protein
BF90_2288	COG2333	competence protein COMEC
BF90_2289	COG2131	deaminase
BF90_229	COG0596	Alpha beta hydrolase
BF90_2290	COG1555	photosystem II stabilization
BF90_2290	COG1596	polysaccharide export
BF90_2291	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF90_2292	COG2226	methyltransferase
BF90_2293	COG0799	negative regulation of ribosome biogenesis
BF90_2294	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF90_2296	COG1534	Rna-binding protein
BF90_2298	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF90_2299	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF90_230	COG2814	Major facilitator Superfamily
BF90_2302	COG1191	sigma factor activity
BF90_2304	COG1595	DNA-templated transcription, initiation
BF90_2306	COG0778	Nitroreductase
BF90_2307	COG2357	RelA SpoT domain protein
BF90_2309	COG1785	Belongs to the alkaline phosphatase family
BF90_2311	COG2267	carboxylic ester hydrolase activity
BF90_2318	COG1404	Belongs to the peptidase S8 family
BF90_2319	COG3186	Phenylalanine-4-hydroxylase
BF90_2321	COG2514	catechol 2,3-dioxygenase activity
BF90_2322	COG2259	Doxx family
BF90_2330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_2332	COG1012	belongs to the aldehyde dehydrogenase family
BF90_2332	COG1454	alcohol dehydrogenase
BF90_2333	COG0626	cystathionine gamma-synthase activity
BF90_2334	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF90_2339	COG0768	penicillin binding
BF90_2345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF90_2349	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF90_235	COG2226	methyltransferase
BF90_2351	COG0628	permease
BF90_2355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF90_2357	COG0482	sulfurtransferase activity
BF90_2358	COG1104	cysteine desulfurase activity
BF90_2359	COG1959	2 iron, 2 sulfur cluster binding
BF90_2360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF90_2362	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF90_2364	COG0124	histidyl-tRNA synthetase
BF90_2367	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF90_2369	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF90_2369	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF90_2370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF90_2371	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF90_2371	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF90_2373	COG2244	polysaccharide biosynthetic process
BF90_2374	COG2323	membrane
BF90_2376	COG1862	Preprotein translocase
BF90_2382	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF90_2384	COG0697	spore germination
BF90_2385	COG0697	spore germination
BF90_2386	COG0640	Transcriptional regulator
BF90_2391	COG0157	Belongs to the NadC ModD family
BF90_2392	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF90_2393	COG1104	cysteine desulfurase activity
BF90_2394	COG1827	regulation of RNA biosynthetic process
BF90_2395	COG2258	MOSC domain
BF90_2396	COG0077	Prephenate dehydratase
BF90_2397	COG0577	efflux transmembrane transporter activity
BF90_2398	COG0577	efflux transmembrane transporter activity
BF90_2399	COG1136	(ABC) transporter
BF90_24	COG2521	methyltransferase
BF90_24	COG2136	Putative SAM-dependent methyltransferase
BF90_2400	COG5002	protein histidine kinase activity
BF90_2402	COG0745	RESPONSE REGULATOR receiver
BF90_2403	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF90_2404	COG3290	protein histidine kinase activity
BF90_2406	COG2868	ribosomal protein
BF90_2408	COG1530	ribonuclease E activity
BF90_2409	COG1994	Peptidase M50
BF90_2410	COG0739	heme binding
BF90_2411	COG2894	cell division
BF90_2414	COG1792	Involved in formation and maintenance of cell shape
BF90_2415	COG1077	Cell shape determining protein MreB Mrl
BF90_2419	COG0285	dihydrofolate synthase activity
BF90_2420	COG0525	valine-tRNA ligase activity
BF90_2422	COG1388	LysM domain
BF90_2424	COG0113	porphobilinogen synthase activity
BF90_2425	COG1587	Uroporphyrinogen-III synthase
BF90_2427	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF90_2429	COG1846	Transcriptional regulator
BF90_2430	COG1764	response to oxidative stress
BF90_2433	COG0470	DNA polymerase III
BF90_2433	COG1067	ATP-dependent peptidase activity
BF90_244	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_2443	COG0622	Phosphoesterase
BF90_2444	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF90_2446	COG5401	PFAM Sporulation and spore germination
BF90_2450	COG1309	transcriptional regulator
BF90_2453	COG2197	response regulator
BF90_2454	COG2233	PERMEase
BF90_2456	COG0402	S-adenosylhomocysteine deaminase activity
BF90_2457	COG0402	S-adenosylhomocysteine deaminase activity
BF90_2461	COG0444	Belongs to the ABC transporter superfamily
BF90_2462	COG4608	Belongs to the ABC transporter superfamily
BF90_2463	COG3275	phosphorelay sensor kinase activity
BF90_2464	COG3279	Response regulator of the LytR AlgR family
BF90_2467	COG1983	PspC domain protein
BF90_2468	COG1396	sequence-specific DNA binding
BF90_2469	COG0697	spore germination
BF90_2471	COG1959	2 iron, 2 sulfur cluster binding
BF90_2472	COG1668	transmembrane transport
BF90_2473	COG4152	abc transporter atp-binding protein
BF90_2474	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF90_2475	COG1360	Flagellar Motor Protein
BF90_2476	COG1360	Flagellar Motor Protein
BF90_2477	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF90_2478	COG1876	peptidase activity
BF90_2479	COG0824	Thioesterase
BF90_2480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF90_2481	COG1053	succinate dehydrogenase
BF90_2482	COG2009	succinate dehydrogenase
BF90_2483	COG1719	4-vinyl reductase, 4VR
BF90_2485	COG3118	belongs to the thioredoxin family
BF90_2486	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF90_2487	COG2086	electron transfer activity
BF90_2488	COG1024	Enoyl-CoA hydratase
BF90_2489	COG1309	transcriptional regulator
BF90_2490	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_2494	COG2318	DinB family
BF90_25	COG0018	arginyl-trna synthetase
BF90_2500	COG1131	(ABC) transporter
BF90_2501	COG2205	protein histidine kinase activity
BF90_2502	COG0745	RESPONSE REGULATOR receiver
BF90_2504	COG4895	conserved protein (DUF2196)
BF90_2505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF90_2508	COG4509	Sortase family
BF90_2509	COG1120	ATPase activity
BF90_251	COG1247	-acetyltransferase
BF90_2512	COG5386	Cell surface protein
BF90_2513	COG5386	Cell surface protein
BF90_2515	COG5386	Cell surface protein
BF90_2516	COG1114	Component of the transport system for branched-chain amino acids
BF90_2517	COG1187	pseudouridine synthase activity
BF90_2520	COG1796	DNA polymerase
BF90_2520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF90_2521	COG1286	toxin biosynthetic process
BF90_2527	COG0017	Asparaginyl-tRNA synthetase
BF90_2528	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_2528	COG0072	phenylalanine-tRNA ligase activity
BF90_2530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF90_2532	COG1418	mRNA catabolic process
BF90_2537	COG2814	Major facilitator Superfamily
BF90_2538	COG1566	PFAM secretion protein HlyD family protein
BF90_2539	COG1309	transcriptional regulator
BF90_2540	COG1363	Peptidase, m42
BF90_2544	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF90_2545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF90_2547	COG1484	DNA-dependent DNA replication
BF90_2548	COG3611	Membrane attachment protein
BF90_2550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF90_2551	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF90_2552	COG0237	dephospho-CoA kinase activity
BF90_2553	COG1971	Probably functions as a manganese efflux pump
BF90_2554	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF90_2555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF90_2555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF90_2556	COG5002	protein histidine kinase activity
BF90_2557	COG0745	RESPONSE REGULATOR receiver
BF90_2561	COG0538	isocitrate dehydrogenase activity
BF90_2562	COG0372	Belongs to the citrate synthase family
BF90_2564	COG0628	permease
BF90_2565	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF90_2570	COG1725	Transcriptional regulator
BF90_2571	COG0281	malic enzyme
BF90_2572	COG0587	DNA-directed DNA polymerase activity
BF90_2575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF90_2579	COG4109	DRTGG domain
BF90_2582	COG0006	proline dipeptidase activity
BF90_2589	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_259	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_2590	COG0662	Cupin 2, conserved barrel domain protein
BF90_2592	COG1476	TRANSCRIPTIONal
BF90_2595	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_2596	COG0589	response to stress
BF90_2604	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_2608	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF90_2609	COG0827	DNA restriction-modification system
BF90_261	COG1278	Cold shock
BF90_2610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF90_2611	COG3874	Sporulation protein YtfJ
BF90_2613	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF90_2614	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF90_2616	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF90_2619	COG1104	cysteine desulfurase activity
BF90_2621	COG0583	DNA-binding transcription factor activity
BF90_2622	COG0697	spore germination
BF90_2623	COG1309	transcriptional regulator
BF90_2624	COG1309	transcriptional regulator
BF90_2625	COG1956	GAF domain-containing protein
BF90_2626	COG0626	cystathionine gamma-synthase activity
BF90_2630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF90_2632	COG1595	DNA-templated transcription, initiation
BF90_2634	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF90_2635	COG0454	-acetyltransferase
BF90_2636	COG0517	IMP dehydrogenase activity
BF90_2637	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF90_2639	COG0745	RESPONSE REGULATOR receiver
BF90_264	COG0010	Belongs to the arginase family
BF90_2641	COG0666	response to abiotic stimulus
BF90_2648	COG1609	Transcriptional regulator
BF90_2649	COG4851	CamS sex pheromone cAM373 precursor
BF90_265	COG0561	phosphatase activity
BF90_2650	COG3118	belongs to the thioredoxin family
BF90_2652	COG2309	aminopeptidase activity
BF90_2656	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_2659	COG1674	ftsk spoiiie
BF90_2661	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_2662	COG4848	Belongs to the UPF0354 family
BF90_2663	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF90_2664	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF90_2665	COG1363	Peptidase, m42
BF90_2667	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_2670	COG0510	thiamine kinase activity
BF90_2671	COG1523	belongs to the glycosyl hydrolase 13 family
BF90_2673	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF90_2674	COG1349	DNA-binding transcription factor activity
BF90_2675	COG1187	pseudouridine synthase activity
BF90_2676	COG2244	polysaccharide biosynthetic process
BF90_2677	COG2081	HI0933 family
BF90_2678	COG2814	Major facilitator Superfamily
BF90_2680	COG3832	glyoxalase III activity
BF90_2684	COG1329	Transcriptional regulator
BF90_2686	COG4975	Glucose uptake
BF90_2689	COG0314	molybdopterin synthase activity
BF90_2690	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF90_2691	COG0303	'Molybdopterin
BF90_2693	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF90_2694	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF90_2698	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_2700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF90_2708	COG2814	Major facilitator Superfamily
BF90_2709	COG0475	glutathione-regulated potassium exporter activity
BF90_2710	COG0490	domain, Protein
BF90_2711	COG0582	viral genome integration into host DNA
BF90_2713	COG1136	(ABC) transporter
BF90_2717	COG1242	4 iron, 4 sulfur cluster binding
BF90_2718	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF90_2719	COG1131	(ABC) transporter
BF90_2721	COG1794	racemase activity, acting on amino acids and derivatives
BF90_2725	COG2267	carboxylic ester hydrolase activity
BF90_2726	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF90_2727	COG0671	phosphoesterase, PA-phosphatase related
BF90_2728	COG0438	transferase activity, transferring glycosyl groups
BF90_273	COG0583	DNA-binding transcription factor activity
BF90_2730	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF90_274	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF90_2740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF90_2741	COG5002	protein histidine kinase activity
BF90_2742	COG4191	Histidine kinase
BF90_2743	COG2267	carboxylic ester hydrolase activity
BF90_2744	COG1368	sulfuric ester hydrolase activity
BF90_2747	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF90_2748	COG1116	anion transmembrane transporter activity
BF90_2749	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF90_2754	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF90_2755	COG0494	nUDIX hydrolase
BF90_2760	COG0288	reversible hydration of carbon dioxide
BF90_2762	COG1271	oxidase subunit
BF90_2763	COG1294	oxidase, subunit
BF90_2767	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_277	COG0583	DNA-binding transcription factor activity
BF90_2772	COG1842	Phage shock protein A
BF90_2779	COG5002	protein histidine kinase activity
BF90_278	COG2258	MOSC domain
BF90_2780	COG0745	RESPONSE REGULATOR receiver
BF90_2786	COG1597	lipid kinase activity
BF90_2793	COG0586	Pfam SNARE associated Golgi protein
BF90_2795	COG0577	efflux transmembrane transporter activity
BF90_2796	COG1136	(ABC) transporter
BF90_2797	COG3708	Transcriptional regulator
BF90_2797	COG2207	Transcriptional regulator
BF90_2798	COG0745	RESPONSE REGULATOR receiver
BF90_2799	COG2205	protein histidine kinase activity
BF90_2800	COG0577	efflux transmembrane transporter activity
BF90_2801	COG0577	efflux transmembrane transporter activity
BF90_2802	COG1136	(ABC) transporter
BF90_2803	COG0577	efflux transmembrane transporter activity
BF90_2804	COG0577	efflux transmembrane transporter activity
BF90_281	COG1132	(ABC) transporter
BF90_2811	COG3964	amidohydrolase
BF90_2817	COG4948	Mandelate Racemase Muconate Lactonizing
BF90_2819	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF90_282	COG1132	(ABC) transporter
BF90_2820	COG0596	Alpha beta hydrolase
BF90_2821	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF90_2822	COG1169	isochorismate synthase
BF90_2823	COG1575	Belongs to the MenA family. Type 1 subfamily
BF90_2824	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF90_2825	COG1278	Cold shock
BF90_2829	COG0058	SHG alpha-glucan phosphorylase activity
BF90_2830	COG0297	glycogen (starch) synthase activity
BF90_2831	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF90_2832	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF90_2834	COG0039	L-malate dehydrogenase activity
BF90_2853	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF90_286	COG1396	sequence-specific DNA binding
BF90_2861	COG1285	pathogenesis
BF90_2863	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF90_2864	COG0166	Belongs to the GPI family
BF90_2865	COG2155	Conserved Protein
BF90_2866	COG1098	S1 RNA binding domain
BF90_2867	COG0436	Aminotransferase
BF90_2868	COG1522	sequence-specific DNA binding
BF90_2869	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF90_2870	COG2267	carboxylic ester hydrolase activity
BF90_2872	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF90_2876	COG5018	Exonuclease
BF90_2877	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF90_2880	COG0423	glycine-tRNA ligase activity
BF90_2881	COG2050	protein possibly involved in aromatic compounds catabolism
BF90_2883	COG1268	BioY protein
BF90_2885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF90_2886	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF90_2889	COG3584	3D domain protein
BF90_2892	COG1252	NADH dehydrogenase
BF90_2895	COG3708	Transcriptional regulator
BF90_2898	COG1683	Conserved Protein
BF90_2901	COG0316	Belongs to the HesB IscA family
BF90_2904	COG1252	NADH dehydrogenase
BF90_2905	COG2274	protein secretion by the type I secretion system
BF90_2906	COG0390	transport system, permease component
BF90_2907	COG2824	Alkylphosphonate utilization operon protein PhnA
BF90_2915	COG4837	Protein of unknown function (DUF1462)
BF90_2916	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF90_2918	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF90_2919	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF90_292	COG1595	DNA-templated transcription, initiation
BF90_2921	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF90_2922	COG0647	UMP catabolic process
BF90_2924	COG2445	Protein of unknown function DUF86
BF90_2925	COG1494	fructose-1,6-bisphosphatase
BF90_2927	COG4470	Protein conserved in bacteria
BF90_2930	COG0789	Transcriptional regulator
BF90_2931	COG4377	Putative membrane peptidase family (DUF2324)
BF90_2936	COG0739	heme binding
BF90_2938	COG3377	Domain of unknown function (DUF1805)
BF90_2939	COG0737	Belongs to the 5'-nucleotidase family
BF90_2940	COG1695	Transcriptional regulator
BF90_2942	COG0719	Fe-S assembly protein
BF90_2943	COG0822	iron-sulfur transferase activity
BF90_2944	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF90_2945	COG0719	Fe-S assembly protein
BF90_2946	COG0396	ATPase activity
BF90_2947	COG1464	Belongs to the NlpA lipoprotein family
BF90_2948	COG1464	Belongs to the NlpA lipoprotein family
BF90_2949	COG2011	ABC-type metal ion transport system permease component
BF90_2950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF90_2952	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF90_2953	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF90_2955	COG1393	Belongs to the ArsC family
BF90_2956	COG1393	Belongs to the ArsC family
BF90_2965	COG0039	L-malate dehydrogenase activity
BF90_297	COG1649	PFAM Uncharacterised BCR, COG1649
BF90_2970	COG1309	transcriptional regulator
BF90_2971	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_2972	COG1960	acyl-CoA dehydrogenase activity
BF90_2973	COG0183	Belongs to the thiolase family
BF90_2974	COG1024	Enoyl-CoA hydratase
BF90_2974	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF90_2976	COG1686	Belongs to the peptidase S11 family
BF90_2979	COG0011	TIGRFAM Protein of
BF90_2980	COG0840	transmembrane signaling receptor activity
BF90_2984	COG2814	Major facilitator Superfamily
BF90_2985	COG0531	amino acid
BF90_2987	COG0706	membrane insertase activity
BF90_2989	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_2996	COG0586	Pfam SNARE associated Golgi protein
BF90_2998	COG1376	ErfK ybiS ycfS ynhG family protein
BF90_2999	COG0745	RESPONSE REGULATOR receiver
BF90_3000	COG5002	protein histidine kinase activity
BF90_3002	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_3005	COG2151	metal-sulfur cluster biosynthetic enzyme
BF90_3006	COG3227	Zinc metalloprotease (Elastase)
BF90_3007	COG1741	Belongs to the pirin family
BF90_3010	COG0475	glutathione-regulated potassium exporter activity
BF90_3011	COG0490	domain, Protein
BF90_3012	COG1115	amino acid carrier protein
BF90_3013	COG0783	Belongs to the Dps family
BF90_3016	COG1611	Belongs to the LOG family
BF90_3019	COG2311	Membrane
BF90_302	COG2971	BadF BadG BcrA BcrD
BF90_3021	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_3022	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_3023	COG1115	amino acid carrier protein
BF90_3024	COG1115	amino acid carrier protein
BF90_3025	COG2910	NAD(P)H-binding
BF90_303	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF90_3030	COG0656	L-ascorbic acid biosynthetic process
BF90_3031	COG2814	Major facilitator Superfamily
BF90_3032	COG1733	regulation of RNA biosynthetic process
BF90_3034	COG1252	NADH dehydrogenase
BF90_3035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF90_3036	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF90_3037	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF90_3039	COG3290	protein histidine kinase activity
BF90_3039	COG0840	transmembrane signaling receptor activity
BF90_304	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF90_3041	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF90_3042	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF90_3045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_3046	COG3223	Belongs to the PsiE family
BF90_3055	COG0557	exoribonuclease II activity
BF90_3056	COG1647	Serine aminopeptidase, S33
BF90_3057	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF90_3058	COG1346	cytolysis
BF90_3079	COG4695	Portal protein
BF90_308	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_3083	COG4974	Belongs to the 'phage' integrase family
BF90_3086	COG0149	triose-phosphate isomerase activity
BF90_3088	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF90_3091	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF90_3096	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_3099	COG2323	membrane
BF90_31	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF90_3100	COG0740	serine-type endopeptidase activity
BF90_3101	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF90_3103	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF90_3105	COG1051	belongs to the nudix hydrolase family
BF90_3107	COG0492	ferredoxin-NADP+ reductase activity
BF90_3108	COG0457	Tetratricopeptide repeat
BF90_3109	COG0110	maltose O-acetyltransferase activity
BF90_3113	COG1950	PFAM Membrane protein of
BF90_3115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF90_3116	COG0556	nucleotide-excision repair
BF90_3120	COG0789	Transcriptional regulator
BF90_3124	COG2855	membrane
BF90_3125	COG0583	DNA-binding transcription factor activity
BF90_3126	COG0583	DNA-binding transcription factor activity
BF90_3128	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF90_313	COG1309	transcriptional regulator
BF90_3131	COG1132	(ABC) transporter
BF90_3132	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF90_3133	COG0793	Belongs to the peptidase S41A family
BF90_3133	COG3409	Peptidoglycan-binding domain 1 protein
BF90_3134	COG2177	Part of the ABC transporter FtsEX involved in
BF90_3135	COG2884	Cell division ATP-binding protein ftsE
BF90_3137	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF90_3138	COG0653	protein targeting
BF90_3139	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF90_3140	COG1278	Cold shock
BF90_3141	COG1040	competence protein
BF90_3142	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF90_3143	COG0791	NLP P60 protein
BF90_3143	COG1388	LysM domain
BF90_3144	COG1733	regulation of RNA biosynthetic process
BF90_3145	COG1307	EDD domain protein, DegV family
BF90_3146	COG1739	Uncharacterized protein family UPF0029
BF90_3147	COG1316	TRANSCRIPTIONal
BF90_3148	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF90_3149	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF90_3150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF90_3152	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF90_3152	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF90_3155	COG3394	polysaccharide catabolic process
BF90_3156	COG1486	melibiose metabolic process
BF90_3157	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF90_3158	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF90_316	COG1136	(ABC) transporter
BF90_316	COG0577	efflux transmembrane transporter activity
BF90_3160	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF90_3161	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF90_3162	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF90_3164	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF90_3165	COG1301	dicarboxylic acid transport
BF90_3167	COG0346	lactoylglutathione lyase activity
BF90_3168	COG1511	domain protein
BF90_3169	COG0583	DNA-binding transcription factor activity
BF90_317	COG3615	Tellurite resistance protein tehB
BF90_317	COG0500	methyltransferase
BF90_3170	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF90_3173	COG1271	oxidase subunit
BF90_3174	COG1294	oxidase, subunit
BF90_3175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF90_3177	COG1620	l-lactate permease
BF90_3179	COG2389	metal-binding protein
BF90_3181	COG1368	sulfuric ester hydrolase activity
BF90_3184	COG0791	NLP P60 protein
BF90_3184	COG1388	LysM domain
BF90_3185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_3187	COG1215	transferase activity, transferring glycosyl groups
BF90_3189	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF90_319	COG2226	methyltransferase
BF90_3190	COG3584	3D domain protein
BF90_3190	COG1388	LysM domain
BF90_3195	COG4715	Zinc finger, swim domain protein
BF90_3196	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF90_320	COG3961	Belongs to the TPP enzyme family
BF90_3202	COG1191	sigma factor activity
BF90_3204	COG0577	efflux transmembrane transporter activity
BF90_3205	COG1136	(ABC) transporter
BF90_321	COG1846	Transcriptional regulator
BF90_3212	COG5002	protein histidine kinase activity
BF90_3213	COG0745	RESPONSE REGULATOR receiver
BF90_3214	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF90_3217	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF90_3218	COG1134	teichoic acid transport
BF90_3219	COG1682	transport, permease protein
BF90_3220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF90_3228	COG1609	Transcriptional regulator
BF90_3230	COG0739	heme binding
BF90_3233	COG3279	Response regulator of the LytR AlgR family
BF90_3234	COG4555	ABC transporter
BF90_3235	COG2385	sporulation resulting in formation of a cellular spore
BF90_3236	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF90_3238	COG4836	Membrane
BF90_3239	COG1007	ATP synthesis coupled electron transport
BF90_3240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF90_3241	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF90_3243	COG0839	Belongs to the complex I subunit 6 family
BF90_3246	COG0649	NAD binding
BF90_3247	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF90_3249	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF90_3250	COG5001	Diguanylate cyclase
BF90_3250	COG3300	MHYT domain
BF90_3260	COG0356	it plays a direct role in the translocation of protons across the membrane
BF90_3266	COG0698	ribose 5-phosphate isomerase
BF90_3268	COG2190	(PTS) system
BF90_3269	COG2259	Doxx family
BF90_3270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF90_3273	COG0009	L-threonylcarbamoyladenylate synthase
BF90_3276	COG2890	protein-(glutamine-N5) methyltransferase activity
BF90_3277	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF90_3280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF90_3281	COG1494	fructose-1,6-bisphosphatase
BF90_3282	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF90_3285	COG4821	SIS domain
BF90_3287	COG3343	RNA polymerase activity
BF90_3289	COG1960	acyl-CoA dehydrogenase activity
BF90_329	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF90_3290	COG1960	acyl-CoA dehydrogenase activity
BF90_3291	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF90_3292	COG0183	Belongs to the thiolase family
BF90_3293	COG2181	nitrate reductase activity
BF90_3293	COG0247	lactate metabolic process
BF90_3294	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF90_3296	COG5001	Diguanylate cyclase
BF90_3296	COG3300	MHYT domain
BF90_3300	COG2197	response regulator
BF90_3301	COG4585	Histidine kinase
BF90_3302	COG0842	Transport permease protein
BF90_3303	COG1131	(ABC) transporter
BF90_3304	COG0024	Methionine aminopeptidase
BF90_3307	COG2234	aminopeptidase activity
BF90_3311	COG1595	DNA-templated transcription, initiation
BF90_3312	COG0018	arginyl-trna synthetase
BF90_3313	COG4506	Protein conserved in bacteria
BF90_3314	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF90_3317	COG0010	Belongs to the arginase family
BF90_3318	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF90_3319	COG2814	Major facilitator Superfamily
BF90_3320	COG0789	Transcriptional regulator
BF90_3321	COG0584	glycerophosphoryl diester phosphodiesterase
BF90_3322	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF90_3324	COG1994	Peptidase M50
BF90_3326	COG1078	dGTPase activity
BF90_3327	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_3328	COG1120	ATPase activity
BF90_3329	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_333	COG1595	DNA-templated transcription, initiation
BF90_3330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_3334	COG0095	Lipoate-protein ligase
BF90_3335	COG0280	phosphate acetyltransferase
BF90_3338	COG3773	Cell wall hydrolase
BF90_3340	COG2363	Small membrane protein
BF90_3342	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF90_3343	COG2233	PERMEase
BF90_3344	COG0561	phosphatase activity
BF90_3345	COG2814	Major facilitator Superfamily
BF90_3347	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF90_3348	COG1131	(ABC) transporter
BF90_3349	COG2755	lipolytic protein G-D-S-L family
BF90_335	COG0768	penicillin binding
BF90_3350	COG1609	Transcriptional regulator
BF90_3352	COG0460	homoserine dehydrogenase
BF90_3356	COG1011	Hydrolase
BF90_3357	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF90_3359	COG2197	response regulator
BF90_3360	COG4585	Histidine kinase
BF90_3360	COG2203	Gaf domain
BF90_3361	COG4585	Histidine kinase
BF90_3361	COG2203	Gaf domain
BF90_3362	COG0351	phosphomethylpyrimidine kinase
BF90_3363	COG3706	GGDEF domain
BF90_3364	COG2879	small protein
BF90_3365	COG1966	Carbon starvation protein
BF90_3366	COG3279	Response regulator of the LytR AlgR family
BF90_3367	COG0477	Major facilitator Superfamily
BF90_337	COG2367	Beta-lactamase
BF90_3372	COG0840	transmembrane signaling receptor activity
BF90_3374	COG1607	acyl-coa hydrolase
BF90_3377	COG0488	(ABC) transporter
BF90_338	COG1609	Transcriptional regulator
BF90_3382	COG0463	Glycosyl transferase, family 2
BF90_3383	COG1309	transcriptional regulator
BF90_3384	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF90_3385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF90_3385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF90_3386	COG0628	permease
BF90_3389	COG3279	Response regulator of the LytR AlgR family
BF90_339	COG2814	Major facilitator Superfamily
BF90_3390	COG3275	phosphorelay sensor kinase activity
BF90_3391	COG2814	Major facilitator Superfamily
BF90_3392	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF90_3393	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF90_3394	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF90_3395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF90_3399	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF90_34	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF90_340	COG2814	Major facilitator Superfamily
BF90_3400	COG1272	protein, Hemolysin III
BF90_3405	COG1164	Oligoendopeptidase f
BF90_3406	COG1164	Oligoendopeptidase f
BF90_341	COG0673	inositol 2-dehydrogenase activity
BF90_3410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF90_3411	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF90_3412	COG4853	Protein conserved in bacteria
BF90_3413	COG4863	YycH protein
BF90_3414	COG5002	protein histidine kinase activity
BF90_3415	COG0745	RESPONSE REGULATOR receiver
BF90_3421	COG0305	Participates in initiation and elongation during chromosome replication
BF90_3423	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF90_3424	COG4241	membrane
BF90_3426	COG0629	single-stranded DNA binding
BF90_3428	COG0012	GTP binding
BF90_3429	COG4481	Protein conserved in bacteria
BF90_343	COG1012	belongs to the aldehyde dehydrogenase family
BF90_3430	COG0668	transmembrane transport
BF90_3432	COG1475	DNA binding
BF90_3433	COG1192	Involved in chromosome partitioning
BF90_3437	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF90_3438	COG1847	R3H domain protein
BF90_3439	COG0706	membrane insertase activity
BF90_3443	COG0592	DNA-directed DNA polymerase activity
BF90_3444	COG2501	S4 domain
BF90_3446	COG0187	DNA topoisomerase II activity
BF90_3447	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF90_3455	COG0517	IMP dehydrogenase activity
BF90_3455	COG0516	GMP reductase activity
BF90_3456	COG1686	Belongs to the peptidase S11 family
BF90_3462	COG1428	Deoxynucleoside kinase
BF90_3463	COG1428	Deoxynucleoside kinase
BF90_3464	COG1335	isochorismatase
BF90_3465	COG0590	tRNA wobble adenosine to inosine editing
BF90_3466	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF90_3476	COG1982	Orn Lys Arg decarboxylase major
BF90_3478	COG0470	DNA polymerase III
BF90_3479	COG1774	PSP1 C-terminal conserved region
BF90_3481	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF90_3483	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF90_3484	COG2002	toxin-antitoxin pair type II binding
BF90_3485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_3485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_3486	COG0084	hydrolase, TatD family'
BF90_3487	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF90_3490	COG4466	Protein conserved in bacteria
BF90_3493	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF90_3494	COG0251	oxidation-reduction process
BF90_3497	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF90_3498	COG0193	aminoacyl-tRNA hydrolase activity
BF90_35	COG0017	Asparaginyl-tRNA synthetase
BF90_3500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF90_3501	COG2002	toxin-antitoxin pair type II binding
BF90_3502	COG2244	polysaccharide biosynthetic process
BF90_3503	COG3956	TIGRFAM MazG family protein
BF90_3504	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF90_3508	COG1098	S1 RNA binding domain
BF90_351	COG0737	Belongs to the 5'-nucleotidase family
BF90_3511	COG2208	phosphoserine phosphatase activity
BF90_3512	COG0037	tRNA processing
BF90_3514	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF90_3517	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF90_3518	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF90_3519	COG0512	Glutamine amidotransferase of anthranilate synthase
BF90_3520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF90_3521	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF90_3522	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF90_3523	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF90_3524	COG1396	sequence-specific DNA binding
BF90_3525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF90_353	COG0457	Tetratricopeptide repeat
BF90_3532	COG3880	PFAM UvrB UvrC protein
BF90_3534	COG0542	response to heat
BF90_3535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF90_3537	COG4956	integral membrane protein (PIN domain superfamily)
BF90_354	COG1476	TRANSCRIPTIONal
BF90_3541	COG1045	serine acetyltransferase
BF90_3544	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF90_3545	COG3688	RNA-binding protein containing a PIN domain
BF90_3547	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF90_3548	COG0250	Participates in transcription elongation, termination and antitermination
BF90_3553	COG2813	Specifically methylates the guanine in position
BF90_3555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF90_3556	COG1358	cellular component organization or biogenesis
BF90_357	COG1876	peptidase activity
BF90_3577	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF90_3582	COG0201	protein transport
BF90_3584	COG0024	Methionine aminopeptidase
BF90_3586	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF90_3592	COG1122	ATPase activity
BF90_3593	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF90_3594	COG0101	tRNA pseudouridine synthase activity
BF90_3598	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF90_3599	COG0489	protein tyrosine kinase activity
BF90_3601	COG2194	sulfuric ester hydrolase activity
BF90_3602	COG0726	polysaccharide deacetylase
BF90_362	COG1309	transcriptional regulator
BF90_3620	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF90_3621	COG4856	YbbR-like protein
BF90_3623	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF90_3624	COG0596	Alpha beta hydrolase
BF90_3628	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF90_3629	COG4946	Tricorn protease homolog
BF90_3629	COG1506	peptidase
BF90_3629	COG0823	Involved in the tonB-independent uptake of proteins
BF90_3636	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_3637	COG2011	ABC-type metal ion transport system permease component
BF90_3638	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF90_3639	COG1464	Belongs to the NlpA lipoprotein family
BF90_3642	COG0277	FAD linked oxidase domain protein
BF90_3643	COG0277	FAD linked oxidase domain protein
BF90_3644	COG2271	Major facilitator Superfamily
BF90_3646	COG2814	Major facilitator Superfamily
BF90_3649	COG0601	transmembrane transport
BF90_3650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF90_3651	COG0444	Belongs to the ABC transporter superfamily
BF90_3652	COG4608	Belongs to the ABC transporter superfamily
BF90_3653	COG4166	transmembrane transport
BF90_3655	COG2207	Transcriptional regulator
BF90_3658	COG4166	transmembrane transport
BF90_3659	COG4166	transmembrane transport
BF90_366	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_3660	COG0656	L-ascorbic acid biosynthetic process
BF90_3661	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF90_3664	COG4149	molybdate abc transporter
BF90_3665	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF90_3666	COG1910	domain protein
BF90_3669	COG0583	DNA-binding transcription factor activity
BF90_3670	COG0697	spore germination
BF90_3673	COG0204	Acyl-transferase
BF90_3675	COG1609	Transcriptional regulator
BF90_3677	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_3680	COG0084	hydrolase, TatD family'
BF90_3681	COG5298	Protein conserved in bacteria
BF90_3685	COG0488	(ABC) transporter
BF90_3688	COG0747	negative chemotaxis
BF90_3689	COG0601	transmembrane transport
BF90_3691	COG0444	Belongs to the ABC transporter superfamily
BF90_3692	COG4608	Belongs to the ABC transporter superfamily
BF90_3693	COG0561	phosphatase activity
BF90_3694	COG0561	phosphatase activity
BF90_3699	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF90_370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_3700	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF90_3702	COG2814	Major facilitator Superfamily
BF90_3705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF90_3707	COG0457	Tetratricopeptide repeat
BF90_3707	COG0705	Rhomboid family
BF90_3708	COG4294	response to UV
BF90_3710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF90_3711	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF90_3712	COG0864	Transcriptional regulator
BF90_3713	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF90_3714	COG2183	response to ionizing radiation
BF90_373	COG1131	(ABC) transporter
BF90_3733	COG0802	atpase or kinase
BF90_3734	COG1214	PFAM Peptidase M22, glycoprotease
BF90_3735	COG0456	acetyltransferase
BF90_3736	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF90_3737	COG0488	(ABC) transporter
BF90_3740	COG1266	CAAX protease self-immunity
BF90_3744	COG2252	PERMEase
BF90_3746	COG5002	protein histidine kinase activity
BF90_375	COG1309	transcriptional regulator
BF90_3751	COG1968	undecaprenyl-diphosphatase activity
BF90_3754	COG2205	protein histidine kinase activity
BF90_3755	COG0745	RESPONSE REGULATOR receiver
BF90_3760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF90_3761	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF90_3762	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF90_3764	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF90_3767	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF90_3769	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF90_3771	COG0151	Belongs to the GarS family
BF90_3776	COG0210	DNA helicase
BF90_3778	COG4851	CamS sex pheromone cAM373 precursor
BF90_378	COG1960	acyl-CoA dehydrogenase activity
BF90_3782	COG1335	isochorismatase
BF90_3783	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF90_3784	COG2011	ABC-type metal ion transport system permease component
BF90_3785	COG1464	Belongs to the NlpA lipoprotein family
BF90_3788	COG0003	Pfam Anion-transporting ATPase
BF90_3789	COG0003	Pfam Anion-transporting ATPase
BF90_379	COG0439	Biotin carboxylase
BF90_3790	COG1846	Transcriptional regulator
BF90_3791	COG4682	membrane
BF90_3795	COG1597	lipid kinase activity
BF90_3796	COG0546	phosphoglycolate phosphatase activity
BF90_3797	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF90_3799	COG1012	belongs to the aldehyde dehydrogenase family
BF90_380	COG0511	ligase activity, forming carbon-carbon bonds
BF90_3800	COG2076	Multidrug Resistance protein
BF90_3801	COG2309	aminopeptidase activity
BF90_3804	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_3805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF90_3806	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF90_3808	COG4807	Protein conserved in bacteria
BF90_381	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF90_3814	COG1473	amidohydrolase
BF90_3817	COG0450	alkyl hydroperoxide reductase
BF90_3818	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF90_382	COG1024	Enoyl-CoA hydratase
BF90_3820	COG0235	Class ii aldolase
BF90_3821	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_3822	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_3823	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_3826	COG0166	Belongs to the GPI family
BF90_383	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF90_3832	COG5002	protein histidine kinase activity
BF90_3836	COG3541	Predicted nucleotidyltransferase
BF90_3837	COG2814	Major facilitator Superfamily
BF90_3838	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF90_3838	COG0723	plastoquinol--plastocyanin reductase activity
BF90_384	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF90_3840	COG0765	amino acid transport
BF90_3841	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF90_3843	COG0840	transmembrane signaling receptor activity
BF90_3844	COG0840	transmembrane signaling receptor activity
BF90_3845	COG0366	Alpha amylase catalytic
BF90_3846	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_3846	COG1263	PTS System
BF90_3846	COG2190	(PTS) system
BF90_3852	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF90_3855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF90_3857	COG1116	anion transmembrane transporter activity
BF90_3858	COG0488	(ABC) transporter
BF90_386	COG1247	-acetyltransferase
BF90_3868	COG2270	Major facilitator Superfamily
BF90_387	COG0572	uridine kinase
BF90_3871	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF90_3874	COG2310	stress, protein
BF90_3875	COG2310	stress, protein
BF90_3876	COG2310	stress, protein
BF90_3877	COG0861	Integral membrane protein TerC family
BF90_3879	COG3853	Toxic anion resistance protein (TelA)
BF90_3882	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF90_3884	COG1295	ribonuclease BN
BF90_3885	COG2217	Heavy metal translocating P-type atpase
BF90_3886	COG0697	spore germination
BF90_389	COG2318	DinB family
BF90_3890	COG0586	Pfam SNARE associated Golgi protein
BF90_3893	COG3871	stress protein (general stress protein 26)
BF90_3894	COG0387	Pfam Sodium calcium exchanger
BF90_3896	COG0535	radical SAM domain protein
BF90_39	COG1674	ftsk spoiiie
BF90_390	COG1686	Belongs to the peptidase S11 family
BF90_3901	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF90_3902	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF90_3903	COG0582	viral genome integration into host DNA
BF90_3907	COG1396	sequence-specific DNA binding
BF90_3914	COG1484	DNA-dependent DNA replication
BF90_3935	COG0582	viral genome integration into host DNA
BF90_3936	COG0582	viral genome integration into host DNA
BF90_395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF90_3962	COG0101	tRNA pseudouridine synthase activity
BF90_3964	COG3829	transcription factor binding
BF90_3966	COG0833	amino acid
BF90_3967	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF90_3972	COG2066	Belongs to the glutaminase family
BF90_3973	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_3973	COG1263	PTS System
BF90_3974	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF90_3977	COG0463	Glycosyl transferase, family 2
BF90_3980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF90_3980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF90_3983	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF90_3987	COG1228	amidohydrolase
BF90_3988	COG1090	epimerase
BF90_399	COG3227	Zinc metalloprotease (Elastase)
BF90_3994	COG1988	membrane-bound metal-dependent
BF90_3995	COG1194	a g-specific adenine glycosylase
BF90_4000	COG1132	(ABC) transporter
BF90_4001	COG4129	membrane
BF90_4002	COG0069	glutamate synthase activity
BF90_4002	COG0067	glutamate synthase
BF90_4002	COG0070	glutamate synthase
BF90_4004	COG4555	ABC transporter
BF90_4008	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF90_4009	COG0735	belongs to the Fur family
BF90_4034	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF90_4035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF90_4037	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF90_4039	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF90_404	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF90_404	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF90_4042	COG2766	serine protein kinase
BF90_4046	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF90_4048	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF90_4049	COG2268	Band 7 protein
BF90_4051	COG3290	protein histidine kinase activity
BF90_4052	COG4565	transcriptional regulatory protein
BF90_4053	COG2851	Citrate transporter
BF90_4057	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF90_4058	COG3842	ATPase activity
BF90_4059	COG1175	transmembrane transport
BF90_4060	COG0395	ABC-type sugar transport system, permease component
BF90_4063	COG0745	RESPONSE REGULATOR receiver
BF90_4064	COG5002	protein histidine kinase activity
BF90_4066	COG4990	cell redox homeostasis
BF90_4068	COG3290	protein histidine kinase activity
BF90_4069	COG4565	transcriptional regulatory protein
BF90_407	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF90_4070	COG3493	citrate carrier protein
BF90_4071	COG0281	malic enzyme
BF90_4074	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_4076	COG5002	protein histidine kinase activity
BF90_4077	COG0745	RESPONSE REGULATOR receiver
BF90_4079	COG0454	-acetyltransferase
BF90_4079	COG0456	acetyltransferase
BF90_4080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF90_4081	COG3383	formate dehydrogenase (NAD+) activity
BF90_4083	COG2427	Protein of unknown function (DUF1641)
BF90_4086	COG0531	amino acid
BF90_4087	COG0640	Transcriptional regulator
BF90_4088	COG2217	Heavy metal translocating P-type atpase
BF90_4089	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF90_409	COG2814	Major facilitator Superfamily
BF90_4092	COG3227	Zinc metalloprotease (Elastase)
BF90_4096	COG2720	vancomycin resistance protein
BF90_4097	COG1316	TRANSCRIPTIONal
BF90_4098	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_4099	COG0346	lactoylglutathione lyase activity
BF90_4100	COG1253	flavin adenine dinucleotide binding
BF90_4101	COG1027	Aspartate ammonia-lyase
BF90_4102	COG1620	l-lactate permease
BF90_4105	COG3104	oligopeptide transport
BF90_4106	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF90_4107	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_4108	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF90_4110	COG2226	methyltransferase
BF90_4111	COG0156	8-amino-7-oxononanoate synthase activity
BF90_4112	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF90_4114	COG4548	von Willebrand factor, type A
BF90_4115	COG0714	Associated with various cellular activities
BF90_4116	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF90_4120	COG0531	amino acid
BF90_4121	COG2188	Transcriptional regulator
BF90_4122	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_4122	COG1263	PTS System
BF90_4123	COG0366	Alpha amylase catalytic
BF90_4126	COG0697	spore germination
BF90_4128	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF90_4129	COG1115	amino acid carrier protein
BF90_413	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF90_4130	COG1126	abc transporter atp-binding protein
BF90_4131	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF90_4132	COG0765	amino acid transport
BF90_4133	COG0765	amino acid transport
BF90_4134	COG0833	amino acid
BF90_4139	COG2378	regulation of single-species biofilm formation
BF90_4140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF90_4141	COG5002	protein histidine kinase activity
BF90_4144	COG0659	secondary active sulfate transmembrane transporter activity
BF90_4147	COG0747	negative chemotaxis
BF90_4149	COG0601	transmembrane transport
BF90_4150	COG4608	Belongs to the ABC transporter superfamily
BF90_4152	COG2271	Major facilitator Superfamily
BF90_4153	COG1846	Transcriptional regulator
BF90_4154	COG0477	Major facilitator Superfamily
BF90_4155	COG0477	Major facilitator Superfamily
BF90_4156	COG1609	Transcriptional regulator
BF90_4157	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF90_4159	COG1129	ABC transporter
BF90_4160	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF90_4161	COG1879	ABC-type sugar transport system periplasmic component
BF90_4162	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF90_4166	COG1063	alcohol dehydrogenase
BF90_4169	COG3568	Endonuclease Exonuclease Phosphatase
BF90_417	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_4174	COG1968	undecaprenyl-diphosphatase activity
BF90_4175	COG0840	transmembrane signaling receptor activity
BF90_4176	COG1388	LysM domain
BF90_4176	COG3584	3D domain protein
BF90_4177	COG1476	TRANSCRIPTIONal
BF90_4180	COG3104	oligopeptide transport
BF90_4181	COG1114	Component of the transport system for branched-chain amino acids
BF90_4184	COG1113	amino acid transport
BF90_4185	COG2252	PERMEase
BF90_419	COG1063	alcohol dehydrogenase
BF90_4190	COG0569	domain protein
BF90_4190	COG0475	glutathione-regulated potassium exporter activity
BF90_4193	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF90_4194	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF90_4195	COG4990	cell redox homeostasis
BF90_4198	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF90_4199	COG0697	spore germination
BF90_4200	COG0531	amino acid
BF90_4202	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF90_4203	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF90_4204	COG1918	ferrous iron import across plasma membrane
BF90_4204	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF90_4205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF90_4206	COG0573	inorganic phosphate transmembrane transporter activity
BF90_4207	COG0581	inorganic phosphate transmembrane transporter activity
BF90_4209	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF90_422	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF90_423	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF90_4234	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF90_4238	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF90_4239	COG1116	anion transmembrane transporter activity
BF90_4240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF90_4241	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF90_4242	COG0352	thiamine-phosphate diphosphorylase activity
BF90_4243	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF90_4244	COG2104	thiamine diphosphate biosynthetic process
BF90_4246	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF90_4247	COG0351	phosphomethylpyrimidine kinase
BF90_4254	COG2205	protein histidine kinase activity
BF90_4255	COG2814	Major facilitator Superfamily
BF90_4256	COG1846	Transcriptional regulator
BF90_4259	COG2252	PERMEase
BF90_426	COG3773	Cell wall hydrolase
BF90_4260	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_4261	COG1376	ErfK ybiS ycfS ynhG family protein
BF90_4263	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF90_4264	COG1621	beta-fructofuranosidase activity
BF90_4265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_4265	COG1263	PTS System
BF90_4266	COG1609	Transcriptional regulator
BF90_4268	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF90_4269	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF90_4276	COG0778	Nitroreductase
BF90_4277	COG2719	SpoVR family
BF90_428	COG0745	RESPONSE REGULATOR receiver
BF90_4282	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF90_4283	COG1937	Protein conserved in bacteria
BF90_4284	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_4284	COG0425	Belongs to the sulfur carrier protein TusA family
BF90_4285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_4285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_4286	COG0425	Belongs to the sulfur carrier protein TusA family
BF90_4288	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF90_4290	COG2210	Belongs to the sulfur carrier protein TusA family
BF90_4291	COG0730	response to heat
BF90_4293	COG1316	TRANSCRIPTIONal
BF90_4294	COG0604	alcohol dehydrogenase
BF90_4295	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF90_4298	COG3711	transcriptional antiterminator
BF90_4298	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF90_4299	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF90_430	COG2205	protein histidine kinase activity
BF90_4300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF90_4304	COG3584	3D domain protein
BF90_4304	COG1388	LysM domain
BF90_4305	COG0577	efflux transmembrane transporter activity
BF90_4306	COG1136	(ABC) transporter
BF90_4308	COG5522	Integral membrane protein (intg_mem_TP0381)
BF90_4311	COG1114	Component of the transport system for branched-chain amino acids
BF90_4312	COG3546	catalase activity
BF90_4319	COG0586	Pfam SNARE associated Golgi protein
BF90_4326	COG0531	amino acid
BF90_4327	COG0475	glutathione-regulated potassium exporter activity
BF90_4329	COG1737	Transcriptional regulator
BF90_4331	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF90_4331	COG1263	PTS System
BF90_4333	COG2259	Doxx family
BF90_4336	COG0697	spore germination
BF90_4337	COG1522	sequence-specific DNA binding
BF90_4339	COG2076	Multidrug Resistance protein
BF90_4340	COG2076	Multidrug Resistance protein
BF90_4341	COG1309	transcriptional regulator
BF90_4342	COG2814	Major facilitator Superfamily
BF90_4343	COG1733	regulation of RNA biosynthetic process
BF90_4345	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF90_4346	COG4533	DNA binding
BF90_4347	COG2211	Major facilitator Superfamily
BF90_4349	COG0693	protein deglycase activity
BF90_435	COG1136	(ABC) transporter
BF90_4350	COG0753	catalase activity
BF90_4350	COG0693	protein deglycase activity
BF90_4352	COG0531	amino acid
BF90_4353	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF90_4355	COG1012	belongs to the aldehyde dehydrogenase family
BF90_4356	COG1132	(ABC) transporter
BF90_4357	COG1132	(ABC) transporter
BF90_4358	COG1132	(ABC) transporter
BF90_4359	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF90_436	COG0577	efflux transmembrane transporter activity
BF90_4360	COG0765	amino acid transport
BF90_4361	COG1126	abc transporter atp-binding protein
BF90_4364	COG0189	ligase activity
BF90_437	COG0577	efflux transmembrane transporter activity
BF90_4370	COG0028	Belongs to the TPP enzyme family
BF90_4371	COG3527	Alpha-acetolactate decarboxylase
BF90_4374	COG0561	phosphatase activity
BF90_4376	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF90_4376	COG3409	Peptidoglycan-binding domain 1 protein
BF90_4378	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF90_4381	COG0659	secondary active sulfate transmembrane transporter activity
BF90_4385	COG0653	protein targeting
BF90_4386	COG2244	polysaccharide biosynthetic process
BF90_4388	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF90_4389	COG4196	transglutaminase domain protein
BF90_4392	COG1696	Membrane protein involved in D-alanine export
BF90_4395	COG1024	Enoyl-CoA hydratase
BF90_4398	COG1363	Peptidase, m42
BF90_4402	COG3938	Belongs to the proline racemase family
BF90_4409	COG0601	transmembrane transport
BF90_441	COG0460	homoserine dehydrogenase
BF90_4410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF90_4411	COG0444	Belongs to the ABC transporter superfamily
BF90_4412	COG0444	Belongs to the ABC transporter superfamily
BF90_4413	COG4608	Belongs to the ABC transporter superfamily
BF90_4419	COG0477	Major facilitator Superfamily
BF90_442	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_4420	COG3290	protein histidine kinase activity
BF90_4421	COG4565	transcriptional regulatory protein
BF90_4422	COG3181	Tripartite tricarboxylate transporter family receptor
BF90_4427	COG4978	Transcriptional regulator
BF90_4427	COG0789	Transcriptional regulator
BF90_4430	COG0305	Participates in initiation and elongation during chromosome replication
BF90_4438	COG0477	Major facilitator Superfamily
BF90_444	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF90_4449	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF90_4449	COG3320	Male sterility
BF90_4454	COG1183	phosphatidylcholine synthase activity
BF90_4458	COG2376	Dihydroxyacetone kinase
BF90_4460	COG2376	Dihydroxyacetone kinase
BF90_4461	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF90_4462	COG1959	2 iron, 2 sulfur cluster binding
BF90_4467	COG3437	response regulator, receiver
BF90_4467	COG2770	Histidine kinase
BF90_4478	COG3237	CsbD-like
BF90_4483	COG1191	sigma factor activity
BF90_4485	COG2208	phosphoserine phosphatase activity
BF90_4486	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF90_4487	COG2205	protein histidine kinase activity
BF90_4487	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF90_4487	COG0784	Response regulator, receiver
BF90_4487	COG2198	Histidine kinase
BF90_4492	COG0393	Putative heavy-metal-binding
BF90_4498	COG0420	3'-5' exonuclease activity
BF90_4499	COG4717	serine-type aminopeptidase activity
BF90_4503	COG1309	transcriptional regulator
BF90_4504	COG2814	Major facilitator Superfamily
BF90_4505	COG0346	lactoylglutathione lyase activity
BF90_4506	COG0346	lactoylglutathione lyase activity
BF90_4507	COG0457	Tetratricopeptide repeat
BF90_4509	COG2267	carboxylic ester hydrolase activity
BF90_4514	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF90_4515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF90_4517	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF90_4525	COG0477	Major facilitator Superfamily
BF90_4526	COG0477	Major facilitator Superfamily
BF90_4528	COG3973	AAA domain
BF90_4529	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF90_4533	COG4980	gas vesicle protein
BF90_4534	COG0537	adenosine 5'-monophosphoramidase activity
BF90_4535	COG1131	(ABC) transporter
BF90_4536	COG4473	ABC transporter
BF90_4539	COG1309	transcriptional regulator
BF90_4541	COG3402	PFAM membrane-flanked domain
BF90_4543	COG3428	Bacterial PH domain
BF90_4552	COG3402	PFAM membrane-flanked domain
BF90_4553	COG3428	Bacterial PH domain
BF90_4554	COG2329	Antibiotic biosynthesis monooxygenase
BF90_4555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF90_4556	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF90_4565	COG1309	transcriptional regulator
BF90_4566	COG1511	domain protein
BF90_4571	COG1609	Transcriptional regulator
BF90_4573	COG1234	tRNA 3'-trailer cleavage
BF90_4574	COG0095	Lipoate-protein ligase
BF90_4576	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_4582	COG3209	COG3209 Rhs family protein
BF90_4589	COG1408	metallophosphoesterase
BF90_4590	COG1078	dGTPase activity
BF90_4592	COG1595	DNA-templated transcription, initiation
BF90_4593	COG3708	Transcriptional regulator
BF90_4593	COG2207	Transcriptional regulator
BF90_4596	COG2205	protein histidine kinase activity
BF90_4597	COG0745	RESPONSE REGULATOR receiver
BF90_460	COG2124	cytochrome p450
BF90_4602	COG0501	Belongs to the peptidase M48B family
BF90_4603	COG0840	transmembrane signaling receptor activity
BF90_4604	COG0697	spore germination
BF90_4607	COG0497	DNA recombination
BF90_4608	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF90_4609	COG2224	Isocitrate lyase
BF90_4611	COG1278	Cold shock
BF90_4614	COG4903	ComK protein
BF90_4615	COG0398	Pfam SNARE associated Golgi protein
BF90_4617	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF90_4618	COG1074	ATP-dependent DNA helicase activity
BF90_4627	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF90_4632	COG0367	asparagine synthase
BF90_4634	COG0753	catalase activity
BF90_4635	COG0004	ammonium transporteR
BF90_4640	COG2996	Protein conserved in bacteria
BF90_4642	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF90_4644	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_4647	COG0561	phosphatase activity
BF90_4649	COG0542	response to heat
BF90_4651	COG2267	carboxylic ester hydrolase activity
BF90_4654	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_4655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF90_4656	COG5504	Zn-dependent protease
BF90_4658	COG0180	Tryptophanyl-tRNA synthetase
BF90_4660	COG4166	transmembrane transport
BF90_4661	COG0601	transmembrane transport
BF90_4662	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF90_4663	COG0444	Belongs to the ABC transporter superfamily
BF90_4664	COG4608	Belongs to the ABC transporter superfamily
BF90_4665	COG0534	Mate efflux family protein
BF90_4666	COG4166	transmembrane transport
BF90_4668	COG1393	Belongs to the ArsC family
BF90_4669	COG0861	Integral membrane protein TerC family
BF90_467	COG0561	phosphatase activity
BF90_4670	COG4862	establishment of competence for transformation
BF90_4671	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF90_4673	COG1164	Oligoendopeptidase f
BF90_4676	COG2346	COG2346, Truncated hemoglobins
BF90_4677	COG4116	CYTH
BF90_4679	COG2357	RelA SpoT domain protein
BF90_4680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF90_4681	COG0564	pseudouridine synthase activity
BF90_4684	COG0772	Belongs to the SEDS family
BF90_4685	COG0772	Belongs to the SEDS family
BF90_4686	COG1216	Glycosyl transferase, family 2
BF90_469	COG5002	protein histidine kinase activity
BF90_4690	COG0463	Glycosyl transferase, family 2
BF90_4690	COG0457	Tetratricopeptide repeat
BF90_4695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF90_4698	COG1088	dTDP-glucose 4,6-dehydratase activity
BF90_4699	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF90_4707	COG2153	protein acetylation
BF90_4708	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF90_4709	COG2382	esterase
BF90_471	COG1819	glycosyl
BF90_4712	COG5492	domain, Protein
BF90_4713	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF90_4715	COG0512	Glutamine amidotransferase of anthranilate synthase
BF90_4715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF90_472	COG1794	racemase activity, acting on amino acids and derivatives
BF90_4722	COG1620	l-lactate permease
BF90_4723	COG5634	Uncharacterized conserved protein (DUF2278)
BF90_4733	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF90_4735	COG1476	TRANSCRIPTIONal
BF90_474	COG1122	ATPase activity
BF90_4746	COG2226	methyltransferase
BF90_4748	COG1686	Belongs to the peptidase S11 family
BF90_4749	COG0681	Belongs to the peptidase S26 family
BF90_4755	COG1012	belongs to the aldehyde dehydrogenase family
BF90_4756	COG3842	ATPase activity
BF90_4757	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF90_4758	COG1177	transmembrane transport
BF90_4759	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF90_4761	COG2409	Drug exporters of the RND superfamily
BF90_4763	COG0564	pseudouridine synthase activity
BF90_4765	COG2340	Cysteine-rich secretory protein family
BF90_4766	COG0247	lactate metabolic process
BF90_4767	COG0277	FAD linked oxidase domain protein
BF90_4768	COG3835	regulator
BF90_477	COG2205	protein histidine kinase activity
BF90_4770	COG0745	RESPONSE REGULATOR receiver
BF90_4771	COG5002	protein histidine kinase activity
BF90_4772	COG2186	Transcriptional regulator
BF90_4776	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF90_4778	COG2116	formate transmembrane transporter activity
BF90_4779	COG0861	Integral membrane protein TerC family
BF90_4780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF90_4781	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF90_4783	COG2030	dehydratase
BF90_4787	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_4788	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF90_4790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF90_4793	COG1840	ABC-type Fe3 transport system, periplasmic component
BF90_4795	COG3842	ATPase activity
BF90_4796	COG3842	ATPase activity
BF90_4799	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF90_480	COG0604	alcohol dehydrogenase
BF90_4803	COG1349	DNA-binding transcription factor activity
BF90_4808	COG0235	Class ii aldolase
BF90_4811	COG2861	carbohydrate metabolic process
BF90_4813	COG3852	Histidine kinase
BF90_4814	COG1846	Transcriptional regulator
BF90_4816	COG2318	DinB family
BF90_4818	COG5002	protein histidine kinase activity
BF90_4820	COG0720	synthase
BF90_4823	COG4873	Protein conserved in bacteria
BF90_4829	COG1780	Probably involved in ribonucleotide reductase function
BF90_483	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF90_4830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF90_4832	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF90_4833	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF90_4834	COG1725	Transcriptional regulator
BF90_4835	COG1131	(ABC) transporter
BF90_4837	COG1131	(ABC) transporter
BF90_4838	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF90_4841	COG1522	sequence-specific DNA binding
BF90_4843	COG1335	isochorismatase
BF90_4845	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF90_4846	COG2070	2-Nitropropane dioxygenase
BF90_4847	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF90_4849	COG1696	Membrane protein involved in D-alanine export
BF90_4854	COG0716	FMN binding
BF90_4857	COG3173	Aminoglycoside phosphotransferase
BF90_4861	COG0534	Mate efflux family protein
BF90_4862	COG1968	undecaprenyl-diphosphatase activity
BF90_4865	COG1846	Transcriptional regulator
BF90_4867	COG1301	dicarboxylic acid transport
BF90_4868	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF90_4869	COG4709	membrane
BF90_4870	COG3874	Sporulation protein YtfJ
BF90_4875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF90_4876	COG0028	Belongs to the TPP enzyme family
BF90_4877	COG0440	acetolactate synthase activity
BF90_4878	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF90_4880	COG0473	3-isopropylmalate dehydrogenase activity
BF90_4885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF90_4892	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF90_4895	COG1183	phosphatidylcholine synthase activity
BF90_4896	COG1368	sulfuric ester hydrolase activity
BF90_4898	COG0019	diaminopimelate decarboxylase activity
BF90_490	COG0693	protein deglycase activity
BF90_4902	COG0529	Catalyzes the synthesis of activated sulfate
BF90_4903	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF90_4907	COG1648	precorrin-2 dehydrogenase activity
BF90_4908	COG0733	neurotransmitter:sodium symporter activity
BF90_4912	COG1757	Na H antiporter
BF90_4915	COG4758	membrane
BF90_4916	COG4585	Histidine kinase
BF90_4917	COG2197	response regulator
BF90_4919	COG1114	Component of the transport system for branched-chain amino acids
BF90_4921	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF90_4926	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF90_4926	COG1017	nitric oxide dioxygenase activity
BF90_4929	COG0730	response to heat
BF90_4930	COG0306	phosphate transporter
BF90_4931	COG1392	Phosphate transport regulator
BF90_4932	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF90_4935	COG3852	Histidine kinase
BF90_4936	COG1801	Protein of unknown function DUF72
BF90_4938	COG0582	viral genome integration into host DNA
BF90_4939	COG5002	protein histidine kinase activity
BF90_4943	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF90_4943	COG0392	lysyltransferase activity
BF90_4946	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF90_4947	COG1686	Belongs to the peptidase S11 family
BF90_4948	COG2715	membrane protein required for spore maturation
BF90_4949	COG0700	Nucleoside recognition
BF90_495	COG2814	Major facilitator Superfamily
BF90_4950	COG1187	pseudouridine synthase activity
BF90_4952	COG1333	cytochrome c biogenesis protein
BF90_4953	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF90_4954	COG0745	RESPONSE REGULATOR receiver
BF90_4955	COG5002	protein histidine kinase activity
BF90_4956	COG2096	Adenosyltransferase
BF90_4959	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF90_4960	COG1141	Ferredoxin
BF90_4961	COG4955	Helix-turn-helix domain
BF90_4962	COG0514	ATP-dependent DNA helicase (RecQ)
BF90_4963	COG1266	CAAX protease self-immunity
BF90_4965	COG1408	metallophosphoesterase
BF90_4967	COG4862	establishment of competence for transformation
BF90_4968	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF90_4972	COG0492	ferredoxin-NADP+ reductase activity
BF90_4973	COG0252	asparaginase activity
BF90_4987	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF90_499	COG0584	glycerophosphoryl diester phosphodiesterase
BF90_4990	COG0142	geranyltranstransferase activity
BF90_4992	COG0142	geranyltranstransferase activity
BF90_4993	COG0105	UTP biosynthetic process
BF90_4996	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF90_4997	COG0457	Tetratricopeptide repeat
BF90_5001	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF90_5003	COG4347	Protein of unknown function (DUF1405)
BF90_5006	COG2738	Putative neutral zinc metallopeptidase
BF90_5008	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_5009	COG1694	Mazg nucleotide pyrophosphohydrolase
BF90_5012	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF90_5013	COG0438	transferase activity, transferring glycosyl groups
BF90_502	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_5020	COG1199	ATP-dependent helicase activity
BF90_5020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF90_5021	COG1199	ATP-dependent helicase activity
BF90_5021	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF90_5025	COG3935	DnaD domain protein
BF90_5026	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF90_5028	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF90_5028	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF90_503	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_5037	COG4474	Belongs to the UPF0398 family
BF90_5039	COG0116	Belongs to the methyltransferase superfamily
BF90_504	COG0697	spore germination
BF90_5041	COG1199	ATP-dependent helicase activity
BF90_5042	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF90_5044	COG3173	Aminoglycoside phosphotransferase
BF90_5045	COG0024	Methionine aminopeptidase
BF90_5047	COG2233	PERMEase
BF90_5048	COG2311	Membrane
BF90_505	COG0697	spore germination
BF90_5050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF90_5052	COG0456	acetyltransferase
BF90_5057	COG0754	glutathionylspermidine amidase activity
BF90_5060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF90_5065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF90_5068	COG1215	transferase activity, transferring glycosyl groups
BF90_5071	COG0438	transferase activity, transferring glycosyl groups
BF90_5074	COG0454	-acetyltransferase
BF90_5078	COG0328	RNA-DNA hybrid ribonuclease activity
BF90_5086	COG1280	lysine exporter protein (LysE YggA)
BF90_5089	COG3162	membrane
BF90_5090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF90_5091	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF90_5093	COG0475	glutathione-regulated potassium exporter activity
BF90_5094	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF90_5095	COG0789	Transcriptional regulator
BF90_5095	COG4978	Transcriptional regulator
BF90_5097	COG2323	membrane
BF90_5098	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF90_5109	COG1923	regulation of RNA biosynthetic process
BF90_5111	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF90_5112	COG1360	Flagellar Motor Protein
BF90_5113	COG2201	protein-glutamate methylesterase activity
BF90_5114	COG2198	Histidine kinase
BF90_5114	COG0643	Histidine kinase
BF90_5115	COG0643	Histidine kinase
BF90_5115	COG2198	Histidine kinase
BF90_5116	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF90_5116	COG1776	CheC inhibitor of MCP methylation
BF90_5119	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF90_512	COG2223	nitrite transmembrane transporter activity
BF90_5124	COG1256	bacterial-type flagellum assembly
BF90_5125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF90_5130	COG1815	bacterial-type flagellum-dependent cell motility
BF90_5131	COG1558	bacterial-type flagellum-dependent cell motility
BF90_5132	COG1677	Flagellar hook-basal body complex protein FliE
BF90_5133	COG1766	The M ring may be actively involved in energy transduction
BF90_5135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF90_5137	COG1157	protein secretion by the type III secretion system
BF90_514	COG2816	NAD+ diphosphatase activity
BF90_5146	COG0784	Response regulator, receiver
BF90_5146	COG0835	chemotaxis
BF90_5148	COG0463	Glycosyl transferase, family 2
BF90_515	COG0592	DNA-directed DNA polymerase activity
BF90_5154	COG0463	Glycosyl transferase, family 2
BF90_5154	COG0457	Tetratricopeptide repeat
BF90_5159	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF90_516	COG1051	belongs to the nudix hydrolase family
BF90_5160	COG0741	lytic transglycosylase activity
BF90_5161	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF90_5163	COG1776	CheC inhibitor of MCP methylation
BF90_5163	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF90_5165	COG1338	Plays a role in the flagellum-specific transport system
BF90_5166	COG1987	bacterial-type flagellum assembly
BF90_5169	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF90_5170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF90_5171	COG1419	protein localization to endoplasmic reticulum
BF90_5172	COG4786	Flagellar basal body rod
BF90_5173	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF90_5178	COG1309	transcriptional regulator
BF90_5182	COG2329	Antibiotic biosynthesis monooxygenase
BF90_5188	COG0583	DNA-binding transcription factor activity
BF90_5189	COG3842	ATPase activity
BF90_5190	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF90_5191	COG1177	transmembrane transport
BF90_5192	COG1234	tRNA 3'-trailer cleavage
BF90_5197	COG1686	Belongs to the peptidase S11 family
BF90_5199	COG0406	alpha-ribazole phosphatase activity
BF90_5206	COG0367	asparagine synthase
BF90_5212	COG1802	Transcriptional regulator
BF90_5213	COG0697	spore germination
BF90_5214	COG0523	cobalamin synthesis protein
BF90_5215	COG0701	Predicted permease
BF90_5217	COG0438	transferase activity, transferring glycosyl groups
BF90_5217	COG1216	Glycosyl transferase, family 2
BF90_5218	COG1757	Na H antiporter
BF90_5219	COG0114	fumarate hydratase activity
BF90_5223	COG0534	Mate efflux family protein
BF90_5224	COG0534	Mate efflux family protein
BF90_5225	COG3340	Belongs to the peptidase S51 family
BF90_5229	COG0785	Cytochrome C biogenesis protein
BF90_523	COG3878	Protein conserved in bacteria
BF90_5236	COG2733	membrane
BF90_5243	COG1131	(ABC) transporter
BF90_5246	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF90_5247	COG0528	UMP kinase activity
BF90_5249	COG1027	Aspartate ammonia-lyase
BF90_5250	COG0281	malic enzyme
BF90_5251	COG4191	Histidine kinase
BF90_5252	COG0784	Response regulator, receiver
BF90_5254	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF90_5266	COG1051	belongs to the nudix hydrolase family
BF90_5267	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF90_5272	COG1966	Carbon starvation protein
BF90_5274	COG0477	Major facilitator Superfamily
BF90_5275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_5277	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF90_5279	COG4166	transmembrane transport
BF90_5280	COG2223	nitrite transmembrane transporter activity
BF90_5281	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF90_5284	COG2244	polysaccharide biosynthetic process
BF90_5285	COG0733	neurotransmitter:sodium symporter activity
BF90_5287	COG5566	PFAM Mor transcription activator
BF90_5288	COG2323	membrane
BF90_529	COG4667	esterase of the alpha-beta hydrolase superfamily
BF90_5291	COG2084	Dehydrogenase
BF90_5295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF90_5297	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF90_5298	COG0028	Belongs to the TPP enzyme family
BF90_5299	COG0440	acetolactate synthase activity
BF90_5300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF90_5302	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF90_5304	COG2843	Capsule synthesis protein
BF90_5310	COG3384	dioxygenase
BF90_5312	COG3279	Response regulator of the LytR AlgR family
BF90_5313	COG0427	acetyl-CoA hydrolase
BF90_5317	COG1073	alpha beta
BF90_5319	COG4166	transmembrane transport
BF90_5324	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_5328	COG1914	H( )-stimulated, divalent metal cation uptake system
BF90_5331	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF90_5333	COG0531	amino acid
BF90_5334	COG0531	amino acid
BF90_5339	COG2390	Transcriptional regulator
BF90_534	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF90_5341	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_5342	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF90_5344	COG4224	UPF0291 protein
BF90_5348	COG0006	proline dipeptidase activity
BF90_5349	COG2132	Multicopper oxidase
BF90_5355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF90_5356	COG1114	Component of the transport system for branched-chain amino acids
BF90_5357	COG1114	Component of the transport system for branched-chain amino acids
BF90_5359	COG2372	response to copper ion
BF90_5359	COG1276	copper resistance
BF90_5360	COG4549	nuclear export factor GLE1
BF90_5362	COG0697	spore germination
BF90_5363	COG0583	DNA-binding transcription factor activity
BF90_5364	COG1959	2 iron, 2 sulfur cluster binding
BF90_5365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF90_5366	COG0778	Nitroreductase
BF90_5369	COG0628	permease
BF90_537	COG0322	excinuclease ABC activity
BF90_5370	COG0039	L-malate dehydrogenase activity
BF90_5371	COG1231	oxidoreductase activity
BF90_5372	COG0523	cobalamin synthesis protein
BF90_5375	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_5376	COG2030	dehydratase
BF90_5377	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF90_5379	COG0411	ABC transporter
BF90_5383	COG0583	DNA-binding transcription factor activity
BF90_5387	COG1846	Transcriptional regulator
BF90_5389	COG1271	oxidase subunit
BF90_5390	COG1294	oxidase, subunit
BF90_5391	COG4988	ABC transporter
BF90_5392	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF90_5396	COG1686	Belongs to the peptidase S11 family
BF90_5398	COG0791	NLP P60 protein
BF90_5398	COG1388	LysM domain
BF90_5400	COG1132	(ABC) transporter
BF90_5401	COG1132	(ABC) transporter
BF90_5402	COG0745	RESPONSE REGULATOR receiver
BF90_5404	COG5002	protein histidine kinase activity
BF90_5406	COG0300	oxidoreductase activity
BF90_5408	COG0726	polysaccharide deacetylase
BF90_5412	COG0460	homoserine dehydrogenase
BF90_5417	COG1316	TRANSCRIPTIONal
BF90_5419	COG0745	RESPONSE REGULATOR receiver
BF90_5420	COG5002	protein histidine kinase activity
BF90_5421	COG0726	polysaccharide deacetylase
BF90_5423	COG1285	pathogenesis
BF90_5424	COG1247	-acetyltransferase
BF90_5426	COG4264	IucA IucC family
BF90_5427	COG0318	PFAM AMP-dependent synthetase and ligase
BF90_5430	COG1082	Xylose isomerase domain protein TIM barrel
BF90_5432	COG2814	Major facilitator Superfamily
BF90_5433	COG1279	arginine transmembrane transporter activity
BF90_5435	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF90_5442	COG0577	efflux transmembrane transporter activity
BF90_5443	COG2002	toxin-antitoxin pair type II binding
BF90_5444	COG1404	Belongs to the peptidase S8 family
BF90_5445	COG0640	Transcriptional regulator
BF90_5446	COG0667	Aldo Keto reductase
BF90_5447	COG2814	Major facilitator Superfamily
BF90_545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF90_5453	COG0840	transmembrane signaling receptor activity
BF90_5456	COG3949	Membrane
BF90_5457	COG0783	Belongs to the Dps family
BF90_5460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF90_5462	COG1231	oxidoreductase activity
BF90_5464	COG4989	oxidoreductase activity
BF90_5465	COG0523	cobalamin synthesis protein
BF90_5466	COG0456	acetyltransferase
BF90_5476	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF90_5476	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF90_5478	COG0702	epimerase
BF90_5480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF90_5482	COG4166	transmembrane transport
BF90_5485	COG0406	alpha-ribazole phosphatase activity
BF90_5487	COG5337	Spore coat protein CotH
BF90_5488	COG1051	belongs to the nudix hydrolase family
BF90_5489	COG0586	Pfam SNARE associated Golgi protein
BF90_5490	COG2244	polysaccharide biosynthetic process
BF90_5492	COG0701	Predicted permease
BF90_5493	COG3689	TIGRFAM TIGR03943 family protein
BF90_5494	COG1607	acyl-coa hydrolase
BF90_5495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF90_5498	COG0702	epimerase
BF90_5499	COG2839	Protein conserved in bacteria
BF90_550	COG1011	Hydrolase
BF90_5500	COG1253	flavin adenine dinucleotide binding
BF90_5504	COG1114	Component of the transport system for branched-chain amino acids
BF90_5505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF90_5509	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF90_5511	COG1876	peptidase activity
BF90_5513	COG0154	amidase activity
BF90_5514	COG2211	Major facilitator Superfamily
BF90_5518	COG0561	phosphatase activity
BF90_5520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF90_5524	COG1819	glycosyl
BF90_5525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF90_5526	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_5532	COG0456	acetyltransferase
BF90_554	COG0076	glutamate decarboxylase activity
BF90_5541	COG3874	Sporulation protein YtfJ
BF90_5546	COG2226	methyltransferase
BF90_5550	COG1082	Xylose isomerase domain protein TIM barrel
BF90_5551	COG0346	lactoylglutathione lyase activity
BF90_5553	COG0604	alcohol dehydrogenase
BF90_5554	COG1595	DNA-templated transcription, initiation
BF90_5559	COG0386	Belongs to the glutathione peroxidase family
BF90_5560	COG1305	Transglutaminase-like
BF90_5561	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF90_5562	COG0714	Associated with various cellular activities
BF90_5565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF90_5566	COG1140	nitrate reductase beta subunit
BF90_5567	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF90_5568	COG2181	nitrate reductase activity
BF90_5572	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF90_5573	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF90_5574	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF90_5575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF90_5576	COG0303	'Molybdopterin
BF90_5577	COG0314	molybdopterin synthase activity
BF90_5579	COG2223	nitrite transmembrane transporter activity
BF90_558	COG1523	belongs to the glycosyl hydrolase 13 family
BF90_5582	COG1648	precorrin-2 dehydrogenase activity
BF90_5584	COG1587	Uroporphyrinogen-III synthase
BF90_5584	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF90_5585	COG2146	nitrite reductase [NAD(P)H] activity
BF90_5586	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF90_5587	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF90_559	COG3227	Zinc metalloprotease (Elastase)
BF90_5595	COG3344	reverse transcriptase
BF90_5617	COG1923	regulation of RNA biosynthetic process
BF90_5619	COG0457	Tetratricopeptide repeat
BF90_5624	COG4974	Belongs to the 'phage' integrase family
BF90_5626	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF90_5629	COG2801	Transposase and inactivated derivatives
BF90_563	COG0201	protein transport
BF90_5632	COG2801	Transposase and inactivated derivatives
BF90_5641	COG4974	Belongs to the 'phage' integrase family
BF90_5643	COG2002	toxin-antitoxin pair type II binding
BF90_565	COG0697	spore germination
BF90_566	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_5683	COG2801	Transposase and inactivated derivatives
BF90_5684	COG2801	Transposase and inactivated derivatives
BF90_5688	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF90_5689	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF90_5693	COG0671	phosphoesterase, PA-phosphatase related
BF90_5694	COG4196	transglutaminase domain protein
BF90_57	COG1929	Belongs to the glycerate kinase type-1 family
BF90_5700	COG2311	Membrane
BF90_572	COG4129	membrane
BF90_573	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_5730	COG4962	Type ii secretion system protein e
BF90_576	COG2959	enzyme of heme biosynthesis
BF90_577	COG3773	Cell wall hydrolase
BF90_577	COG3409	Peptidoglycan-binding domain 1 protein
BF90_5774	COG3344	reverse transcriptase
BF90_5795	COG0741	lytic transglycosylase activity
BF90_5795	COG0791	NLP P60 protein
BF90_58	COG0471	metal ion transport
BF90_580	COG3483	tryptophan 2,3-dioxygenase activity
BF90_581	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF90_5810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF90_5811	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF90_582	COG3844	kynureninase activity
BF90_5821	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF90_5825	COG4166	transmembrane transport
BF90_583	COG1309	transcriptional regulator
BF90_5830	COG1280	lysine exporter protein (LysE YggA)
BF90_5838	COG0681	Belongs to the peptidase S26 family
BF90_5855	COG1309	transcriptional regulator
BF90_5856	COG1683	Conserved Protein
BF90_5862	COG2801	Transposase and inactivated derivatives
BF90_5866	COG1192	Involved in chromosome partitioning
BF90_589	COG3284	Transcriptional regulator
BF90_59	COG0745	RESPONSE REGULATOR receiver
BF90_593	COG1349	DNA-binding transcription factor activity
BF90_597	COG1959	2 iron, 2 sulfur cluster binding
BF90_60	COG5002	protein histidine kinase activity
BF90_60	COG3850	Histidine kinase
BF90_601	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF90_602	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF90_603	COG0022	dehydrogenase e1 component
BF90_604	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF90_606	COG1028	Short-chain dehydrogenase reductase Sdr
BF90_607	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF90_607	COG0456	acetyltransferase
BF90_612	COG4176	ABC-type proline glycine betaine transport system permease component
BF90_613	COG0517	IMP dehydrogenase activity
BF90_613	COG4175	Glycine betaine
BF90_615	COG0740	serine-type endopeptidase activity
BF90_618	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF90_619	COG2153	protein acetylation
BF90_620	COG3397	chitin binding
BF90_624	COG2205	protein histidine kinase activity
BF90_629	COG0658	competence protein
BF90_629	COG2333	competence protein COMEC
BF90_63	COG0733	neurotransmitter:sodium symporter activity
BF90_639	COG3973	AAA domain
BF90_642	COG2105	PFAM AIG2 family protein
BF90_643	COG0514	ATP-dependent DNA helicase (RecQ)
BF90_646	COG4637	Psort location Cytoplasmic, score
BF90_652	COG3397	chitin binding
BF90_654	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF90_655	COG1115	amino acid carrier protein
BF90_656	COG1012	belongs to the aldehyde dehydrogenase family
BF90_657	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF90_659	COG3938	Belongs to the proline racemase family
BF90_660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF90_667	COG0586	Pfam SNARE associated Golgi protein
BF90_670	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF90_671	COG0519	Catalyzes the synthesis of GMP from XMP
BF90_672	COG4166	transmembrane transport
BF90_674	COG4948	Mandelate Racemase Muconate Lactonizing
BF90_68	COG2610	gluconate transmembrane transporter activity
BF90_682	COG2936	dipeptidyl-peptidase activity
BF90_683	COG5002	protein histidine kinase activity
BF90_684	COG0745	RESPONSE REGULATOR receiver
BF90_69	COG1454	alcohol dehydrogenase
BF90_691	COG1164	Oligoendopeptidase f
BF90_694	COG1307	EDD domain protein, DegV family
BF90_698	COG2814	Major facilitator Superfamily
BF90_7	COG2359	stage V sporulation protein S
BF90_70	COG1794	racemase activity, acting on amino acids and derivatives
BF90_700	COG1664	Polymer-forming cytoskeletal
BF90_701	COG0789	Transcriptional regulator
BF90_702	COG4533	DNA binding
BF90_703	COG0477	Major facilitator Superfamily
BF90_703	COG2814	Major facilitator Superfamily
BF90_707	COG2261	transglycosylase associated protein
BF90_710	COG2226	methyltransferase
BF90_716	COG0436	Aminotransferase
BF90_717	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF90_718	COG5146	pantothenate kinase activity
BF90_72	COG0456	acetyltransferase
BF90_722	COG1131	(ABC) transporter
BF90_731	COG0628	permease
BF90_733	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF90_734	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF90_735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF90_736	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF90_737	COG1116	anion transmembrane transporter activity
BF90_74	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF90_746	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF90_751	COG0697	spore germination
BF90_752	COG2318	DinB family
BF90_756	COG4912	Dna alkylation repair
BF90_758	COG0726	polysaccharide deacetylase
BF90_76	COG1131	(ABC) transporter
BF90_760	COG0861	Integral membrane protein TerC family
BF90_761	COG1368	sulfuric ester hydrolase activity
BF90_762	COG0488	(ABC) transporter
BF90_764	COG2409	Drug exporters of the RND superfamily
BF90_764	COG1033	growth of symbiont in host cell
BF90_765	COG2409	Drug exporters of the RND superfamily
BF90_765	COG1033	growth of symbiont in host cell
BF90_766	COG1309	transcriptional regulator
BF90_769	COG0287	Prephenate dehydrogenase
BF90_77	COG4473	ABC transporter
BF90_770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF90_771	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF90_772	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF90_772	COG1605	Chorismate mutase
BF90_780	COG3584	3D domain protein
BF90_780	COG1388	LysM domain
BF90_782	COG1595	DNA-templated transcription, initiation
BF90_788	COG1879	ABC-type sugar transport system periplasmic component
BF90_79	COG0546	phosphoglycolate phosphatase activity
BF90_790	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF90_792	COG2390	Transcriptional regulator
BF90_793	COG1070	Carbohydrate kinase
BF90_799	COG2329	Antibiotic biosynthesis monooxygenase
BF90_803	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF90_805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF90_806	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF90_807	COG4187	Peptidase family M20/M25/M40
BF90_808	COG1414	Transcriptional regulator
BF90_809	COG0833	amino acid
BF90_810	COG1690	Belongs to the RtcB family
BF90_811	COG3239	Fatty acid desaturase
BF90_812	COG1785	Belongs to the alkaline phosphatase family
BF90_814	COG3655	Transcriptional regulator
BF90_817	COG4377	Putative membrane peptidase family (DUF2324)
BF90_819	COG3279	Response regulator of the LytR AlgR family
BF90_821	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF90_822	COG0346	lactoylglutathione lyase activity
BF90_826	COG0714	Associated with various cellular activities
BF90_83	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF90_831	COG0463	Glycosyl transferase, family 2
BF90_836	COG0463	Glycosyl transferase, family 2
BF90_838	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF90_839	COG0753	catalase activity
BF90_841	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF90_847	COG0714	Associated with various cellular activities
BF90_849	COG0778	Nitroreductase
BF90_850	COG1846	Transcriptional regulator
BF90_857	COG1725	Transcriptional regulator
BF90_859	COG1136	(ABC) transporter
BF90_859	COG0577	efflux transmembrane transporter activity
BF90_86	COG0768	penicillin binding
BF90_864	COG2207	Transcriptional regulator
BF90_865	COG0456	acetyltransferase
BF90_869	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF90_87	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF90_873	COG0642	Histidine kinase
BF90_874	COG0745	RESPONSE REGULATOR receiver
BF90_875	COG0596	Alpha beta hydrolase
BF90_88	COG0204	Acyl-transferase
BF90_881	COG0730	response to heat
BF90_883	COG0833	amino acid
BF90_885	COG4335	DNA alkylation repair
BF90_89	COG1272	protein, Hemolysin III
BF90_895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF90_902	COG1984	allophanate hydrolase subunit 2
BF90_903	COG1984	allophanate hydrolase subunit 2
BF90_904	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF90_905	COG1414	Transcriptional regulator
BF90_908	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF90_909	COG0640	Transcriptional regulator
BF90_91	COG0805	protein transport
BF90_911	COG1960	acyl-CoA dehydrogenase activity
BF90_918	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF90_921	COG0574	Belongs to the PEP-utilizing enzyme family
BF90_921	COG3848	Pyruvate phosphate dikinase
BF90_922	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF90_925	COG5577	PFAM Coat F domain
BF90_927	COG3403	YqcI/YcgG family
BF90_928	COG1280	lysine exporter protein (LysE YggA)
BF90_929	COG1113	amino acid transport
BF90_93	COG1307	EDD domain protein, DegV family
BF90_930	COG1113	amino acid transport
BF90_936	COG1063	alcohol dehydrogenase
BF90_939	COG1027	Aspartate ammonia-lyase
BF90_94	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF90_940	COG0252	asparaginase activity
BF90_941	COG1396	sequence-specific DNA binding
BF90_943	COG0322	excinuclease ABC activity
BF90_944	COG0531	amino acid
BF90_945	COG1114	Component of the transport system for branched-chain amino acids
BF90_946	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF90_948	COG0281	malic enzyme
BF90_95	COG1999	signal sequence binding
BF90_951	COG0531	amino acid
BF90_952	COG0697	spore germination
BF90_953	COG0697	spore germination
BF90_954	COG0784	Response regulator, receiver
BF90_955	COG4191	Histidine kinase
BF90_956	COG2066	Belongs to the glutaminase family
BF90_958	COG1115	amino acid carrier protein
BF90_96	COG0071	Belongs to the small heat shock protein (HSP20) family
BF90_964	COG0737	Belongs to the 5'-nucleotidase family
BF90_965	COG0753	catalase activity
BF90_966	COG2267	carboxylic ester hydrolase activity
BF90_967	COG1335	isochorismatase
BF90_97	COG0367	asparagine synthase
BF90_971	COG0583	DNA-binding transcription factor activity
BF90_972	COG1846	Transcriptional regulator
BF90_973	COG0598	Magnesium transport protein CorA
BF90_980	COG0415	Belongs to the DNA photolyase family
BF90_981	COG0288	reversible hydration of carbon dioxide
BF90_983	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF90_984	COG5609	conserved protein (DUF2294)
BF90_986	COG1575	Belongs to the MenA family. Type 1 subfamily
BF90_987	COG2267	carboxylic ester hydrolase activity
BF90_988	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF90_989	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF90_990	COG1121	(ABC) transporter
BF90_996	COG0798	PFAM Bile acid sodium symporter
BF90_997	COG0346	lactoylglutathione lyase activity
BF90_998	COG0640	Transcriptional regulator