locus-tag	class	description
KM388_00010	COG0592	DNA-directed DNA polymerase activity
KM388_00015	COG2501	S4 domain
KM388_00025	COG0187	DNA topoisomerase II activity
KM388_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM388_00065	COG0516	GMP reductase activity
KM388_00065	COG0517	IMP dehydrogenase activity
KM388_00070	COG1686	Belongs to the peptidase S11 family
KM388_00100	COG1428	Deoxynucleoside kinase
KM388_00105	COG1428	Deoxynucleoside kinase
KM388_00110	COG1335	isochorismatase
KM388_00115	COG0590	tRNA wobble adenosine to inosine editing
KM388_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM388_00180	COG1982	Orn Lys Arg decarboxylase major
KM388_00190	COG0470	DNA polymerase III
KM388_00195	COG1774	PSP1 C-terminal conserved region
KM388_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM388_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM388_00220	COG2002	toxin-antitoxin pair type II binding
KM388_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM388_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM388_00230	COG0084	hydrolase, TatD family'
KM388_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM388_00250	COG4466	Protein conserved in bacteria
KM388_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM388_00270	COG0251	oxidation-reduction process
KM388_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM388_00305	COG2002	toxin-antitoxin pair type II binding
KM388_00310	COG2244	polysaccharide biosynthetic process
KM388_00315	COG3956	TIGRFAM MazG family protein
KM388_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM388_00340	COG1098	S1 RNA binding domain
KM388_00355	COG2208	phosphoserine phosphatase activity
KM388_00360	COG0037	tRNA processing
KM388_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM388_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM388_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM388_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM388_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM388_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM388_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM388_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM388_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM388_00420	COG1396	sequence-specific DNA binding
KM388_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM388_00455	COG3880	PFAM UvrB UvrC protein
KM388_00465	COG0542	response to heat
KM388_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM388_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM388_00500	COG1045	serine acetyltransferase
KM388_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM388_00520	COG3688	RNA-binding protein containing a PIN domain
KM388_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM388_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM388_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM388_00565	COG2813	Specifically methylates the guanine in position
KM388_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM388_00580	COG1358	cellular component organization or biogenesis
KM388_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM388_00710	COG0201	protein transport
KM388_00720	COG0024	Methionine aminopeptidase
KM388_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM388_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM388_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM388_00795	COG0489	protein tyrosine kinase activity
KM388_00805	COG2194	sulfuric ester hydrolase activity
KM388_00810	COG0726	polysaccharide deacetylase
KM388_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM388_00895	COG4856	YbbR-like protein
KM388_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM388_00915	COG0596	Alpha beta hydrolase
KM388_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM388_00940	COG4946	Tricorn protease homolog
KM388_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM388_00940	COG1506	peptidase
KM388_00975	COG2011	ABC-type metal ion transport system permease component
KM388_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM388_00985	COG1464	Belongs to the NlpA lipoprotein family
KM388_00990	COG0604	alcohol dehydrogenase
KM388_01005	COG2271	Major facilitator Superfamily
KM388_01015	COG2814	Major facilitator Superfamily
KM388_01030	COG0601	transmembrane transport
KM388_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM388_01040	COG0444	Belongs to the ABC transporter superfamily
KM388_01045	COG4608	Belongs to the ABC transporter superfamily
KM388_01050	COG4166	transmembrane transport
KM388_01060	COG2207	Transcriptional regulator
KM388_01075	COG4166	transmembrane transport
KM388_01080	COG4166	transmembrane transport
KM388_01085	COG0656	L-ascorbic acid biosynthetic process
KM388_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM388_01105	COG4149	molybdate abc transporter
KM388_01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM388_01115	COG1910	domain protein
KM388_01125	COG0583	DNA-binding transcription factor activity
KM388_01130	COG0697	spore germination
KM388_01145	COG0204	Acyl-transferase
KM388_01155	COG1609	Transcriptional regulator
KM388_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_01175	COG0084	hydrolase, TatD family'
KM388_01180	COG5298	Protein conserved in bacteria
KM388_01205	COG0488	(ABC) transporter
KM388_01220	COG0747	negative chemotaxis
KM388_01225	COG0601	transmembrane transport
KM388_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM388_01235	COG0444	Belongs to the ABC transporter superfamily
KM388_01240	COG4608	Belongs to the ABC transporter superfamily
KM388_01265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM388_01270	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM388_01280	COG2814	Major facilitator Superfamily
KM388_01290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM388_01300	COG4294	response to UV
KM388_01305	COG0457	Tetratricopeptide repeat
KM388_01305	COG0705	Rhomboid family
KM388_01315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM388_01320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM388_01325	COG0864	Transcriptional regulator
KM388_01330	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM388_01335	COG2183	response to ionizing radiation
KM388_01430	COG0802	atpase or kinase
KM388_01435	COG1214	PFAM Peptidase M22, glycoprotease
KM388_01440	COG0456	acetyltransferase
KM388_01450	COG0488	(ABC) transporter
KM388_01465	COG1266	CAAX protease self-immunity
KM388_01485	COG2252	PERMEase
KM388_01495	COG5002	protein histidine kinase activity
KM388_01515	COG1968	undecaprenyl-diphosphatase activity
KM388_01530	COG2205	protein histidine kinase activity
KM388_01535	COG0745	RESPONSE REGULATOR receiver
KM388_01555	COG1968	undecaprenyl-diphosphatase activity
KM388_01570	COG2205	protein histidine kinase activity
KM388_01575	COG0745	RESPONSE REGULATOR receiver
KM388_01595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM388_01600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM388_01605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM388_01615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM388_01630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM388_01640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM388_01650	COG0151	Belongs to the GarS family
KM388_01675	COG0210	DNA helicase
KM388_01685	COG4851	CamS sex pheromone cAM373 precursor
KM388_01705	COG1335	isochorismatase
KM388_01710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM388_01715	COG2011	ABC-type metal ion transport system permease component
KM388_01720	COG1464	Belongs to the NlpA lipoprotein family
KM388_01740	COG1846	Transcriptional regulator
KM388_01765	COG1597	lipid kinase activity
KM388_01770	COG0546	phosphoglycolate phosphatase activity
KM388_01775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM388_01785	COG1012	belongs to the aldehyde dehydrogenase family
KM388_01790	COG2076	Multidrug Resistance protein
KM388_01795	COG2309	aminopeptidase activity
KM388_01810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_01815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM388_01820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM388_01830	COG4807	Protein conserved in bacteria
KM388_01855	COG1757	Na H antiporter
KM388_01860	COG1473	amidohydrolase
KM388_01875	COG0450	alkyl hydroperoxide reductase
KM388_01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_01905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_01920	COG0166	Belongs to the GPI family
KM388_01955	COG5002	protein histidine kinase activity
KM388_01975	COG3541	Predicted nucleotidyltransferase
KM388_01980	COG2814	Major facilitator Superfamily
KM388_01985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM388_01985	COG0723	plastoquinol--plastocyanin reductase activity
KM388_01995	COG0765	amino acid transport
KM388_02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM388_02010	COG0840	transmembrane signaling receptor activity
KM388_02015	COG0840	transmembrane signaling receptor activity
KM388_02020	COG0366	Alpha amylase catalytic
KM388_02025	COG1263	PTS System
KM388_02025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_02025	COG2190	(PTS) system
KM388_02055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM388_02070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM388_02080	COG1116	anion transmembrane transporter activity
KM388_02085	COG0488	(ABC) transporter
KM388_02130	COG2270	Major facilitator Superfamily
KM388_02145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM388_02160	COG2310	stress, protein
KM388_02165	COG2310	stress, protein
KM388_02170	COG2310	stress, protein
KM388_02175	COG0861	Integral membrane protein TerC family
KM388_02185	COG3853	Toxic anion resistance protein (TelA)
KM388_02200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM388_02210	COG1295	ribonuclease BN
KM388_02215	COG2217	Heavy metal translocating P-type atpase
KM388_02220	COG0697	spore germination
KM388_02240	COG0586	Pfam SNARE associated Golgi protein
KM388_02255	COG3871	stress protein (general stress protein 26)
KM388_02260	COG0387	Pfam Sodium calcium exchanger
KM388_02270	COG0535	radical SAM domain protein
KM388_02295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM388_02300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM388_02305	COG0582	viral genome integration into host DNA
KM388_02315	COG1396	sequence-specific DNA binding
KM388_02330	COG1396	sequence-specific DNA binding
KM388_02365	COG1484	DNA-dependent DNA replication
KM388_02595	COG0101	tRNA pseudouridine synthase activity
KM388_02605	COG3829	transcription factor binding
KM388_02615	COG0833	amino acid
KM388_02620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM388_02650	COG1263	PTS System
KM388_02650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_02655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM388_02670	COG0463	Glycosyl transferase, family 2
KM388_02685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM388_02685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM388_02705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM388_02725	COG1228	amidohydrolase
KM388_02730	COG1090	epimerase
KM388_02760	COG1988	membrane-bound metal-dependent
KM388_02765	COG1194	a g-specific adenine glycosylase
KM388_02790	COG1132	(ABC) transporter
KM388_02795	COG4129	membrane
KM388_02800	COG0069	glutamate synthase activity
KM388_02800	COG0067	glutamate synthase
KM388_02800	COG0070	glutamate synthase
KM388_02810	COG4555	ABC transporter
KM388_02830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM388_02835	COG0735	belongs to the Fur family
KM388_02950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM388_02955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM388_02965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM388_02975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM388_02985	COG2766	serine protein kinase
KM388_03005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM388_03015	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM388_03020	COG2268	Band 7 protein
KM388_03030	COG3290	protein histidine kinase activity
KM388_03035	COG4565	transcriptional regulatory protein
KM388_03040	COG2851	Citrate transporter
KM388_03060	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM388_03065	COG3842	ATPase activity
KM388_03070	COG1175	transmembrane transport
KM388_03075	COG0395	ABC-type sugar transport system, permease component
KM388_03085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM388_03090	COG0745	RESPONSE REGULATOR receiver
KM388_03095	COG5002	protein histidine kinase activity
KM388_03105	COG4990	cell redox homeostasis
KM388_03115	COG3290	protein histidine kinase activity
KM388_03120	COG4565	transcriptional regulatory protein
KM388_03125	COG3493	citrate carrier protein
KM388_03130	COG0281	malic enzyme
KM388_03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_03155	COG5002	protein histidine kinase activity
KM388_03160	COG0745	RESPONSE REGULATOR receiver
KM388_03165	COG0454	-acetyltransferase
KM388_03165	COG0456	acetyltransferase
KM388_03170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM388_03175	COG3383	formate dehydrogenase (NAD+) activity
KM388_03180	COG2427	Protein of unknown function (DUF1641)
KM388_03195	COG0531	amino acid
KM388_03200	COG0640	Transcriptional regulator
KM388_03205	COG2217	Heavy metal translocating P-type atpase
KM388_03210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM388_03225	COG3227	Zinc metalloprotease (Elastase)
KM388_03245	COG2720	vancomycin resistance protein
KM388_03250	COG1316	TRANSCRIPTIONal
KM388_03255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_03260	COG0346	lactoylglutathione lyase activity
KM388_03265	COG1253	flavin adenine dinucleotide binding
KM388_03270	COG1027	Aspartate ammonia-lyase
KM388_03275	COG1620	l-lactate permease
KM388_03290	COG3104	oligopeptide transport
KM388_03295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_03315	COG2226	methyltransferase
KM388_03320	COG0156	8-amino-7-oxononanoate synthase activity
KM388_03325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM388_03335	COG4548	von Willebrand factor, type A
KM388_03340	COG0714	Associated with various cellular activities
KM388_03345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM388_03365	COG0531	amino acid
KM388_03370	COG2188	Transcriptional regulator
KM388_03375	COG1263	PTS System
KM388_03375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_03380	COG0366	Alpha amylase catalytic
KM388_03395	COG0697	spore germination
KM388_03405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM388_03410	COG1115	amino acid carrier protein
KM388_03415	COG1126	abc transporter atp-binding protein
KM388_03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM388_03425	COG0765	amino acid transport
KM388_03430	COG0765	amino acid transport
KM388_03435	COG0833	amino acid
KM388_03460	COG2378	regulation of single-species biofilm formation
KM388_03465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM388_03470	COG5002	protein histidine kinase activity
KM388_03485	COG0659	secondary active sulfate transmembrane transporter activity
KM388_03500	COG0747	negative chemotaxis
KM388_03510	COG0601	transmembrane transport
KM388_03515	COG4608	Belongs to the ABC transporter superfamily
KM388_03525	COG2271	Major facilitator Superfamily
KM388_03530	COG1846	Transcriptional regulator
KM388_03540	COG1609	Transcriptional regulator
KM388_03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM388_03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM388_03565	COG1879	ABC-type sugar transport system periplasmic component
KM388_03590	COG1063	alcohol dehydrogenase
KM388_03605	COG3568	Endonuclease Exonuclease Phosphatase
KM388_03630	COG1968	undecaprenyl-diphosphatase activity
KM388_03635	COG0840	transmembrane signaling receptor activity
KM388_03640	COG3584	3D domain protein
KM388_03640	COG1388	LysM domain
KM388_03645	COG1476	TRANSCRIPTIONal
KM388_03660	COG3104	oligopeptide transport
KM388_03665	COG1114	Component of the transport system for branched-chain amino acids
KM388_03680	COG1113	amino acid transport
KM388_03685	COG2252	PERMEase
KM388_03710	COG0569	domain protein
KM388_03710	COG0475	glutathione-regulated potassium exporter activity
KM388_03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM388_03730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM388_03735	COG0833	amino acid
KM388_03740	COG4990	cell redox homeostasis
KM388_03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM388_03760	COG0697	spore germination
KM388_03765	COG0531	amino acid
KM388_03775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM388_03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM388_03785	COG1918	ferrous iron import across plasma membrane
KM388_03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM388_03790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM388_03795	COG0573	inorganic phosphate transmembrane transporter activity
KM388_03800	COG0581	inorganic phosphate transmembrane transporter activity
KM388_03810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM388_03930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM388_03950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM388_03955	COG1116	anion transmembrane transporter activity
KM388_03960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM388_03965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM388_03970	COG0352	thiamine-phosphate diphosphorylase activity
KM388_03975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM388_03980	COG2104	thiamine diphosphate biosynthetic process
KM388_03990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM388_03995	COG0351	phosphomethylpyrimidine kinase
KM388_04035	COG2205	protein histidine kinase activity
KM388_04040	COG2814	Major facilitator Superfamily
KM388_04045	COG1846	Transcriptional regulator
KM388_04060	COG2252	PERMEase
KM388_04065	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_04070	COG1376	ErfK ybiS ycfS ynhG family protein
KM388_04080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM388_04085	COG1621	beta-fructofuranosidase activity
KM388_04090	COG1263	PTS System
KM388_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_04095	COG1609	Transcriptional regulator
KM388_04105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM388_04145	COG0778	Nitroreductase
KM388_04150	COG2719	SpoVR family
KM388_04175	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM388_04180	COG1937	Protein conserved in bacteria
KM388_04185	COG0425	Belongs to the sulfur carrier protein TusA family
KM388_04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_04195	COG0425	Belongs to the sulfur carrier protein TusA family
KM388_04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_04210	COG2210	Belongs to the sulfur carrier protein TusA family
KM388_04215	COG0730	response to heat
KM388_04225	COG1316	TRANSCRIPTIONal
KM388_04230	COG0604	alcohol dehydrogenase
KM388_04235	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM388_04250	COG3711	transcriptional antiterminator
KM388_04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM388_04255	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM388_04260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM388_04280	COG3584	3D domain protein
KM388_04280	COG1388	LysM domain
KM388_04285	COG0577	efflux transmembrane transporter activity
KM388_04290	COG1136	(ABC) transporter
KM388_04300	COG5522	Integral membrane protein (intg_mem_TP0381)
KM388_04315	COG1114	Component of the transport system for branched-chain amino acids
KM388_04320	COG3546	catalase activity
KM388_04355	COG0586	Pfam SNARE associated Golgi protein
KM388_04390	COG0531	amino acid
KM388_04395	COG0475	glutathione-regulated potassium exporter activity
KM388_04405	COG1737	Transcriptional regulator
KM388_04415	COG1263	PTS System
KM388_04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_04425	COG2259	Doxx family
KM388_04440	COG0697	spore germination
KM388_04445	COG1522	sequence-specific DNA binding
KM388_04460	COG2076	Multidrug Resistance protein
KM388_04465	COG1309	transcriptional regulator
KM388_04470	COG2814	Major facilitator Superfamily
KM388_04475	COG1733	regulation of RNA biosynthetic process
KM388_04485	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM388_04490	COG4533	DNA binding
KM388_04495	COG2814	Major facilitator Superfamily
KM388_04505	COG0693	protein deglycase activity
KM388_04510	COG0753	catalase activity
KM388_04510	COG0693	protein deglycase activity
KM388_04520	COG0531	amino acid
KM388_04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM388_04535	COG1012	belongs to the aldehyde dehydrogenase family
KM388_04540	COG1132	(ABC) transporter
KM388_04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM388_04555	COG0765	amino acid transport
KM388_04560	COG1126	abc transporter atp-binding protein
KM388_04575	COG0189	ligase activity
KM388_04605	COG0028	Belongs to the TPP enzyme family
KM388_04610	COG3527	Alpha-acetolactate decarboxylase
KM388_04625	COG0561	phosphatase activity
KM388_04640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM388_04655	COG0659	secondary active sulfate transmembrane transporter activity
KM388_04675	COG0653	protein targeting
KM388_04680	COG2244	polysaccharide biosynthetic process
KM388_04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM388_04695	COG4196	transglutaminase domain protein
KM388_04710	COG1696	Membrane protein involved in D-alanine export
KM388_04725	COG1024	Enoyl-CoA hydratase
KM388_04740	COG1363	Peptidase, m42
KM388_04760	COG3938	Belongs to the proline racemase family
KM388_04805	COG0601	transmembrane transport
KM388_04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM388_04820	COG4608	Belongs to the ABC transporter superfamily
KM388_04825	COG0322	excinuclease ABC activity
KM388_04855	COG0477	Major facilitator Superfamily
KM388_04860	COG3290	protein histidine kinase activity
KM388_04865	COG4565	transcriptional regulatory protein
KM388_04870	COG3181	Tripartite tricarboxylate transporter family receptor
KM388_04900	COG0789	Transcriptional regulator
KM388_04900	COG4978	Transcriptional regulator
KM388_04915	COG0305	Participates in initiation and elongation during chromosome replication
KM388_04955	COG0477	Major facilitator Superfamily
KM388_05005	COG1309	transcriptional regulator
KM388_05025	COG1183	phosphatidylcholine synthase activity
KM388_05045	COG2376	Dihydroxyacetone kinase
KM388_05055	COG2376	Dihydroxyacetone kinase
KM388_05060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM388_05065	COG1959	2 iron, 2 sulfur cluster binding
KM388_05095	COG2770	Histidine kinase
KM388_05095	COG3437	response regulator, receiver
KM388_05145	COG3237	CsbD-like
KM388_05170	COG1191	sigma factor activity
KM388_05180	COG2208	phosphoserine phosphatase activity
KM388_05185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM388_05190	COG0784	Response regulator, receiver
KM388_05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM388_05190	COG2198	Histidine kinase
KM388_05190	COG2205	protein histidine kinase activity
KM388_05245	COG0420	3'-5' exonuclease activity
KM388_05250	COG4717	serine-type aminopeptidase activity
KM388_05270	COG1309	transcriptional regulator
KM388_05275	COG2814	Major facilitator Superfamily
KM388_05280	COG0346	lactoylglutathione lyase activity
KM388_05285	COG0346	lactoylglutathione lyase activity
KM388_05290	COG0457	Tetratricopeptide repeat
KM388_05295	COG2267	carboxylic ester hydrolase activity
KM388_05315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM388_05320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM388_05330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM388_05370	COG0477	Major facilitator Superfamily
KM388_05375	COG0477	Major facilitator Superfamily
KM388_05385	COG3973	AAA domain
KM388_05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM388_05410	COG4980	gas vesicle protein
KM388_05415	COG0537	adenosine 5'-monophosphoramidase activity
KM388_05420	COG1131	(ABC) transporter
KM388_05425	COG4473	ABC transporter
KM388_05440	COG1309	transcriptional regulator
KM388_05450	COG3402	PFAM membrane-flanked domain
KM388_05495	COG3402	PFAM membrane-flanked domain
KM388_05500	COG3428	Bacterial PH domain
KM388_05505	COG2329	Antibiotic biosynthesis monooxygenase
KM388_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM388_05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM388_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM388_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM388_05560	COG1309	transcriptional regulator
KM388_05565	COG1511	domain protein
KM388_05590	COG1609	Transcriptional regulator
KM388_05600	COG1234	tRNA 3'-trailer cleavage
KM388_05605	COG0095	Lipoate-protein ligase
KM388_05615	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_05645	COG3209	COG3209 Rhs family protein
KM388_05685	COG1078	dGTPase activity
KM388_05695	COG1595	DNA-templated transcription, initiation
KM388_05700	COG2207	Transcriptional regulator
KM388_05700	COG3708	Transcriptional regulator
KM388_05715	COG2205	protein histidine kinase activity
KM388_05720	COG0745	RESPONSE REGULATOR receiver
KM388_05745	COG0501	Belongs to the peptidase M48B family
KM388_05750	COG0840	transmembrane signaling receptor activity
KM388_05755	COG0697	spore germination
KM388_05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM388_05780	COG2224	Isocitrate lyase
KM388_05805	COG4903	ComK protein
KM388_05810	COG0398	Pfam SNARE associated Golgi protein
KM388_05820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM388_05825	COG1074	ATP-dependent DNA helicase activity
KM388_05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM388_05895	COG0367	asparagine synthase
KM388_05900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM388_05905	COG0753	catalase activity
KM388_05910	COG0004	ammonium transporteR
KM388_05930	COG2996	Protein conserved in bacteria
KM388_05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM388_05950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_05965	COG0561	phosphatase activity
KM388_05975	COG0542	response to heat
KM388_05985	COG2267	carboxylic ester hydrolase activity
KM388_06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM388_06010	COG5504	Zn-dependent protease
KM388_06020	COG0180	Tryptophanyl-tRNA synthetase
KM388_06030	COG4166	transmembrane transport
KM388_06035	COG0601	transmembrane transport
KM388_06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM388_06045	COG0444	Belongs to the ABC transporter superfamily
KM388_06050	COG4608	Belongs to the ABC transporter superfamily
KM388_06055	COG0534	Mate efflux family protein
KM388_06060	COG4166	transmembrane transport
KM388_06075	COG0861	Integral membrane protein TerC family
KM388_06080	COG4862	establishment of competence for transformation
KM388_06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM388_06095	COG1164	Oligoendopeptidase f
KM388_06105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM388_06110	COG2346	COG2346, Truncated hemoglobins
KM388_06115	COG4116	CYTH
KM388_06125	COG2357	RelA SpoT domain protein
KM388_06135	COG0564	pseudouridine synthase activity
KM388_06155	COG0463	Glycosyl transferase, family 2
KM388_06155	COG1216	Glycosyl transferase, family 2
KM388_06175	COG0463	Glycosyl transferase, family 2
KM388_06175	COG0457	Tetratricopeptide repeat
KM388_06195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM388_06210	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM388_06255	COG2153	protein acetylation
KM388_06265	COG2382	esterase
KM388_06280	COG5492	domain, Protein
KM388_06285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM388_06295	COG0512	Glutamine amidotransferase of anthranilate synthase
KM388_06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM388_06330	COG1620	l-lactate permease
KM388_06335	COG5634	Uncharacterized conserved protein (DUF2278)
KM388_06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM388_06400	COG1476	TRANSCRIPTIONal
KM388_06460	COG2226	methyltransferase
KM388_06470	COG1686	Belongs to the peptidase S11 family
KM388_06475	COG0681	Belongs to the peptidase S26 family
KM388_06510	COG1012	belongs to the aldehyde dehydrogenase family
KM388_06515	COG3842	ATPase activity
KM388_06520	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM388_06525	COG1177	transmembrane transport
KM388_06530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM388_06540	COG2409	Drug exporters of the RND superfamily
KM388_06550	COG0564	pseudouridine synthase activity
KM388_06560	COG2340	Cysteine-rich secretory protein family
KM388_06565	COG0247	lactate metabolic process
KM388_06570	COG0277	FAD linked oxidase domain protein
KM388_06575	COG3835	regulator
KM388_06585	COG0745	RESPONSE REGULATOR receiver
KM388_06590	COG5002	protein histidine kinase activity
KM388_06595	COG2186	Transcriptional regulator
KM388_06615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM388_06625	COG2116	formate transmembrane transporter activity
KM388_06630	COG0861	Integral membrane protein TerC family
KM388_06645	COG2030	dehydratase
KM388_06665	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_06670	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM388_06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM388_06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM388_06695	COG1840	ABC-type Fe3 transport system, periplasmic component
KM388_06725	COG1349	DNA-binding transcription factor activity
KM388_06745	COG2861	carbohydrate metabolic process
KM388_06755	COG3852	Histidine kinase
KM388_06760	COG1846	Transcriptional regulator
KM388_06770	COG2318	DinB family
KM388_06775	COG5002	protein histidine kinase activity
KM388_06785	COG0720	synthase
KM388_06800	COG4873	Protein conserved in bacteria
KM388_06830	COG1780	Probably involved in ribonucleotide reductase function
KM388_06850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM388_06855	COG1725	Transcriptional regulator
KM388_06860	COG1131	(ABC) transporter
KM388_06870	COG1131	(ABC) transporter
KM388_06875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM388_06890	COG1522	sequence-specific DNA binding
KM388_06900	COG1335	isochorismatase
KM388_06910	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM388_06915	COG2070	2-Nitropropane dioxygenase
KM388_06920	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM388_06930	COG1696	Membrane protein involved in D-alanine export
KM388_06955	COG0716	FMN binding
KM388_06970	COG3173	Aminoglycoside phosphotransferase
KM388_06990	COG0534	Mate efflux family protein
KM388_06995	COG1968	undecaprenyl-diphosphatase activity
KM388_07010	COG1846	Transcriptional regulator
KM388_07020	COG1301	dicarboxylic acid transport
KM388_07025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM388_07030	COG4709	membrane
KM388_07035	COG3874	Sporulation protein YtfJ
KM388_07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM388_07065	COG0028	Belongs to the TPP enzyme family
KM388_07070	COG0440	acetolactate synthase activity
KM388_07075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM388_07085	COG0473	3-isopropylmalate dehydrogenase activity
KM388_07110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM388_07145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM388_07160	COG1183	phosphatidylcholine synthase activity
KM388_07165	COG1368	sulfuric ester hydrolase activity
KM388_07175	COG0019	diaminopimelate decarboxylase activity
KM388_07195	COG0529	Catalyzes the synthesis of activated sulfate
KM388_07200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM388_07220	COG1648	precorrin-2 dehydrogenase activity
KM388_07225	COG0733	neurotransmitter:sodium symporter activity
KM388_07245	COG1757	Na H antiporter
KM388_07260	COG4758	membrane
KM388_07265	COG4585	Histidine kinase
KM388_07270	COG2197	response regulator
KM388_07280	COG1114	Component of the transport system for branched-chain amino acids
KM388_07290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM388_07315	COG1017	nitric oxide dioxygenase activity
KM388_07315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM388_07330	COG0730	response to heat
KM388_07335	COG0306	phosphate transporter
KM388_07340	COG1392	Phosphate transport regulator
KM388_07345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM388_07365	COG1801	Protein of unknown function DUF72
KM388_07375	COG0582	viral genome integration into host DNA
KM388_07380	COG5002	protein histidine kinase activity
KM388_07400	COG0392	lysyltransferase activity
KM388_07400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM388_07415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM388_07420	COG1686	Belongs to the peptidase S11 family
KM388_07425	COG2715	membrane protein required for spore maturation
KM388_07430	COG0700	Nucleoside recognition
KM388_07435	COG1187	pseudouridine synthase activity
KM388_07445	COG1333	cytochrome c biogenesis protein
KM388_07450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM388_07455	COG0745	RESPONSE REGULATOR receiver
KM388_07460	COG5002	protein histidine kinase activity
KM388_07465	COG2096	Adenosyltransferase
KM388_07480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM388_07485	COG1141	Ferredoxin
KM388_07490	COG4955	Helix-turn-helix domain
KM388_07495	COG0514	ATP-dependent DNA helicase (RecQ)
KM388_07500	COG1266	CAAX protease self-immunity
KM388_07520	COG4862	establishment of competence for transformation
KM388_07525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM388_07545	COG0492	ferredoxin-NADP+ reductase activity
KM388_07620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM388_07635	COG0142	geranyltranstransferase activity
KM388_07645	COG0142	geranyltranstransferase activity
KM388_07665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM388_07670	COG0457	Tetratricopeptide repeat
KM388_07690	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM388_07700	COG4347	Protein of unknown function (DUF1405)
KM388_07715	COG2738	Putative neutral zinc metallopeptidase
KM388_07725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_07730	COG1694	Mazg nucleotide pyrophosphohydrolase
KM388_07745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM388_07750	COG0438	transferase activity, transferring glycosyl groups
KM388_07805	COG3935	DnaD domain protein
KM388_07810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM388_07820	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM388_07820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM388_07880	COG0116	Belongs to the methyltransferase superfamily
KM388_07890	COG1199	ATP-dependent helicase activity
KM388_07895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM388_07905	COG3173	Aminoglycoside phosphotransferase
KM388_07910	COG0024	Methionine aminopeptidase
KM388_07920	COG2233	PERMEase
KM388_07925	COG2311	Membrane
KM388_07930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM388_07940	COG0456	acetyltransferase
KM388_07990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM388_08015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM388_08030	COG1215	transferase activity, transferring glycosyl groups
KM388_08050	COG0454	-acetyltransferase
KM388_08070	COG0328	RNA-DNA hybrid ribonuclease activity
KM388_08110	COG1280	lysine exporter protein (LysE YggA)
KM388_08125	COG3162	membrane
KM388_08130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM388_08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM388_08145	COG0475	glutathione-regulated potassium exporter activity
KM388_08150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM388_08155	COG4978	Transcriptional regulator
KM388_08155	COG0789	Transcriptional regulator
KM388_08165	COG2323	membrane
KM388_08170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM388_08225	COG1923	regulation of RNA biosynthetic process
KM388_08235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM388_08240	COG1360	Flagellar Motor Protein
KM388_08245	COG2201	protein-glutamate methylesterase activity
KM388_08250	COG0643	Histidine kinase
KM388_08250	COG2198	Histidine kinase
KM388_08255	COG0643	Histidine kinase
KM388_08255	COG2198	Histidine kinase
KM388_08260	COG1776	CheC inhibitor of MCP methylation
KM388_08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM388_08275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM388_08295	COG1256	bacterial-type flagellum assembly
KM388_08320	COG1815	bacterial-type flagellum-dependent cell motility
KM388_08325	COG1558	bacterial-type flagellum-dependent cell motility
KM388_08340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM388_08350	COG1157	protein secretion by the type III secretion system
KM388_08390	COG0784	Response regulator, receiver
KM388_08390	COG0835	chemotaxis
KM388_08400	COG0463	Glycosyl transferase, family 2
KM388_08435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM388_08440	COG0741	lytic transglycosylase activity
KM388_08455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM388_08455	COG1776	CheC inhibitor of MCP methylation
KM388_08465	COG1338	Plays a role in the flagellum-specific transport system
KM388_08470	COG1987	bacterial-type flagellum assembly
KM388_08480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM388_08485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM388_08490	COG1419	protein localization to endoplasmic reticulum
KM388_08495	COG4786	Flagellar basal body rod
KM388_08500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM388_08525	COG1309	transcriptional regulator
KM388_08545	COG2329	Antibiotic biosynthesis monooxygenase
KM388_08575	COG3842	ATPase activity
KM388_08580	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM388_08590	COG1234	tRNA 3'-trailer cleavage
KM388_08615	COG1686	Belongs to the peptidase S11 family
KM388_08655	COG0367	asparagine synthase
KM388_08685	COG1802	Transcriptional regulator
KM388_08690	COG0697	spore germination
KM388_08695	COG0523	cobalamin synthesis protein
KM388_08700	COG0701	Predicted permease
KM388_08710	COG0438	transferase activity, transferring glycosyl groups
KM388_08710	COG1216	Glycosyl transferase, family 2
KM388_08715	COG1757	Na H antiporter
KM388_08720	COG0114	fumarate hydratase activity
KM388_08745	COG3340	Belongs to the peptidase S51 family
KM388_08765	COG0785	Cytochrome C biogenesis protein
KM388_08795	COG2733	membrane
KM388_08830	COG1131	(ABC) transporter
KM388_08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM388_08850	COG0528	UMP kinase activity
KM388_08860	COG1027	Aspartate ammonia-lyase
KM388_08865	COG0281	malic enzyme
KM388_08870	COG4191	Histidine kinase
KM388_08875	COG0784	Response regulator, receiver
KM388_08880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM388_08940	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM388_08950	COG2814	Major facilitator Superfamily
KM388_08965	COG1966	Carbon starvation protein
KM388_08975	COG0477	Major facilitator Superfamily
KM388_08980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_08990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM388_09020	COG2244	polysaccharide biosynthetic process
KM388_09025	COG0733	neurotransmitter:sodium symporter activity
KM388_09035	COG5566	PFAM Mor transcription activator
KM388_09040	COG2323	membrane
KM388_09055	COG2084	Dehydrogenase
KM388_09070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM388_09080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM388_09085	COG0028	Belongs to the TPP enzyme family
KM388_09090	COG0440	acetolactate synthase activity
KM388_09095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM388_09105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM388_09135	COG3384	dioxygenase
KM388_09145	COG3279	Response regulator of the LytR AlgR family
KM388_09150	COG0427	acetyl-CoA hydrolase
KM388_09170	COG1073	alpha beta
KM388_09175	COG4166	transmembrane transport
KM388_09200	COG0535	radical SAM domain protein
KM388_09205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_09225	COG1914	H( )-stimulated, divalent metal cation uptake system
KM388_09240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM388_09270	COG2390	Transcriptional regulator
KM388_09280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_09285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM388_09300	COG4224	UPF0291 protein
KM388_09320	COG0006	proline dipeptidase activity
KM388_09325	COG2132	Multicopper oxidase
KM388_09340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM388_09355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM388_09370	COG2372	response to copper ion
KM388_09370	COG1276	copper resistance
KM388_09375	COG4549	nuclear export factor GLE1
KM388_09385	COG0697	spore germination
KM388_09390	COG0583	DNA-binding transcription factor activity
KM388_09395	COG1959	2 iron, 2 sulfur cluster binding
KM388_09400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM388_09405	COG0778	Nitroreductase
KM388_09415	COG0628	permease
KM388_09425	COG1231	oxidoreductase activity
KM388_09430	COG0523	cobalamin synthesis protein
KM388_09445	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_09450	COG2030	dehydratase
KM388_09455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_09465	COG0411	ABC transporter
KM388_09485	COG0583	DNA-binding transcription factor activity
KM388_09495	COG1942	4-Oxalocrotonate Tautomerase
KM388_09505	COG1846	Transcriptional regulator
KM388_09515	COG1271	oxidase subunit
KM388_09520	COG1294	oxidase, subunit
KM388_09525	COG4988	ABC transporter
KM388_09530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM388_09550	COG1686	Belongs to the peptidase S11 family
KM388_09565	COG1388	LysM domain
KM388_09565	COG0791	NLP P60 protein
KM388_09580	COG0745	RESPONSE REGULATOR receiver
KM388_09595	COG0300	oxidoreductase activity
KM388_09630	COG0460	homoserine dehydrogenase
KM388_09655	COG1316	TRANSCRIPTIONal
KM388_09665	COG0745	RESPONSE REGULATOR receiver
KM388_09670	COG5002	protein histidine kinase activity
KM388_09685	COG1285	pathogenesis
KM388_09690	COG1247	-acetyltransferase
KM388_09710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM388_09720	COG1082	Xylose isomerase domain protein TIM barrel
KM388_09730	COG2814	Major facilitator Superfamily
KM388_09735	COG1279	arginine transmembrane transporter activity
KM388_09745	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM388_09780	COG0577	efflux transmembrane transporter activity
KM388_09785	COG2002	toxin-antitoxin pair type II binding
KM388_09790	COG1404	Belongs to the peptidase S8 family
KM388_09795	COG0640	Transcriptional regulator
KM388_09800	COG0667	Aldo Keto reductase
KM388_09805	COG2814	Major facilitator Superfamily
KM388_09830	COG0840	transmembrane signaling receptor activity
KM388_09845	COG3949	Membrane
KM388_09850	COG0783	Belongs to the Dps family
KM388_09865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM388_09875	COG1231	oxidoreductase activity
KM388_09885	COG4989	oxidoreductase activity
KM388_09890	COG0523	cobalamin synthesis protein
KM388_09895	COG0456	acetyltransferase
KM388_09950	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM388_09950	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM388_09960	COG0702	epimerase
KM388_09970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM388_09980	COG4166	transmembrane transport
KM388_09995	COG0406	alpha-ribazole phosphatase activity
KM388_10005	COG5337	Spore coat protein CotH
KM388_10010	COG1051	belongs to the nudix hydrolase family
KM388_10015	COG0586	Pfam SNARE associated Golgi protein
KM388_10020	COG2244	polysaccharide biosynthetic process
KM388_10030	COG0701	Predicted permease
KM388_10035	COG3689	TIGRFAM TIGR03943 family protein
KM388_10040	COG1607	acyl-coa hydrolase
KM388_10050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM388_10065	COG0702	epimerase
KM388_10070	COG2839	Protein conserved in bacteria
KM388_10075	COG1253	flavin adenine dinucleotide binding
KM388_10090	COG1114	Component of the transport system for branched-chain amino acids
KM388_10095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM388_10115	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM388_10125	COG1876	peptidase activity
KM388_10135	COG0154	amidase activity
KM388_10140	COG2211	Major facilitator Superfamily
KM388_10160	COG0561	phosphatase activity
KM388_10170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM388_10175	COG4106	trans-aconitate 2-methyltransferase activity
KM388_10190	COG1819	glycosyl
KM388_10195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_10200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_10225	COG0456	acetyltransferase
KM388_10275	COG3874	Sporulation protein YtfJ
KM388_10325	COG0346	lactoylglutathione lyase activity
KM388_10335	COG0604	alcohol dehydrogenase
KM388_10340	COG1595	DNA-templated transcription, initiation
KM388_10365	COG0386	Belongs to the glutathione peroxidase family
KM388_10370	COG1305	Transglutaminase-like
KM388_10375	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM388_10380	COG0714	Associated with various cellular activities
KM388_10395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM388_10400	COG1140	nitrate reductase beta subunit
KM388_10405	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM388_10410	COG2181	nitrate reductase activity
KM388_10430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM388_10435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM388_10440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM388_10445	COG0303	'Molybdopterin
KM388_10450	COG0314	molybdopterin synthase activity
KM388_10460	COG2223	nitrite transmembrane transporter activity
KM388_10475	COG1648	precorrin-2 dehydrogenase activity
KM388_10485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM388_10485	COG1587	Uroporphyrinogen-III synthase
KM388_10490	COG2146	nitrite reductase [NAD(P)H] activity
KM388_10495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM388_10500	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM388_10535	COG2359	stage V sporulation protein S
KM388_10550	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM388_10565	COG1418	mRNA catabolic process
KM388_10570	COG0488	(ABC) transporter
KM388_10585	COG0629	single-stranded DNA binding
KM388_10600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM388_10610	COG1413	lyase activity
KM388_10625	COG2521	methyltransferase
KM388_10625	COG2136	Putative SAM-dependent methyltransferase
KM388_10630	COG0018	arginyl-trna synthetase
KM388_10655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM388_10675	COG0017	Asparaginyl-tRNA synthetase
KM388_10695	COG1674	ftsk spoiiie
KM388_10765	COG1929	Belongs to the glycerate kinase type-1 family
KM388_10770	COG0471	metal ion transport
KM388_10775	COG0745	RESPONSE REGULATOR receiver
KM388_10780	COG5002	protein histidine kinase activity
KM388_10780	COG3850	Histidine kinase
KM388_10795	COG0733	neurotransmitter:sodium symporter activity
KM388_10820	COG2610	gluconate transmembrane transporter activity
KM388_10825	COG1454	alcohol dehydrogenase
KM388_10830	COG1794	racemase activity, acting on amino acids and derivatives
KM388_10840	COG0456	acetyltransferase
KM388_10855	COG1131	(ABC) transporter
KM388_10870	COG0546	phosphoglycolate phosphatase activity
KM388_10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM388_10905	COG0768	penicillin binding
KM388_10910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM388_10915	COG0204	Acyl-transferase
KM388_10920	COG1272	protein, Hemolysin III
KM388_10930	COG0805	protein transport
KM388_10940	COG1307	EDD domain protein, DegV family
KM388_10945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM388_10950	COG1999	signal sequence binding
KM388_10955	COG0071	Belongs to the small heat shock protein (HSP20) family
KM388_10960	COG0367	asparagine synthase
KM388_10975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_10980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM388_11005	COG1051	belongs to the nudix hydrolase family
KM388_11015	COG0668	transmembrane transport
KM388_11020	COG2203	Gaf domain
KM388_11020	COG4585	Histidine kinase
KM388_11025	COG2197	response regulator
KM388_11035	COG1064	alcohol dehydrogenase
KM388_11060	COG1070	Carbohydrate kinase
KM388_11065	COG1070	Carbohydrate kinase
KM388_11095	COG1125	glycine betaine transport
KM388_11095	COG0517	IMP dehydrogenase activity
KM388_11100	COG1174	glycine betaine transport
KM388_11135	COG1253	flavin adenine dinucleotide binding
KM388_11140	COG1012	belongs to the aldehyde dehydrogenase family
KM388_11145	COG5506	Protein of unknown function (DUF1694)
KM388_11160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM388_11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM388_11170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM388_11175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM388_11180	COG0456	acetyltransferase
KM388_11185	COG3829	transcription factor binding
KM388_11190	COG1509	lysine 2,3-aminomutase activity
KM388_11230	COG4326	sporulation control protein
KM388_11235	COG0671	phosphoesterase, PA-phosphatase related
KM388_11240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM388_11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM388_11275	COG1715	Restriction endonuclease
KM388_11275	COG1787	Restriction endonuclease
KM388_11365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM388_11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM388_11405	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM388_11410	COG2814	Major facilitator Superfamily
KM388_11415	COG4841	protein insertion into membrane
KM388_11420	COG0372	Belongs to the citrate synthase family
KM388_11425	COG2079	MmgE PrpD family protein
KM388_11430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM388_11435	COG1960	acyl-CoA dehydrogenase activity
KM388_11440	COG2084	Dehydrogenase
KM388_11450	COG1280	lysine exporter protein (LysE YggA)
KM388_11455	COG1024	Enoyl-CoA hydratase
KM388_11470	COG0420	3'-5' exonuclease activity
KM388_11475	COG0419	ATPase involved in DNA repair
KM388_11495	COG2223	nitrite transmembrane transporter activity
KM388_11500	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_11505	COG1169	isochorismate synthase
KM388_11510	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM388_11515	COG3433	isochorismatase activity
KM388_11515	COG1535	isochorismatase
KM388_11525	COG3251	PFAM MbtH domain protein
KM388_11530	COG2814	Major facilitator Superfamily
KM388_11545	COG0776	regulation of translation
KM388_11555	COG2318	DinB family
KM388_11580	COG2329	Antibiotic biosynthesis monooxygenase
KM388_11585	COG1187	pseudouridine synthase activity
KM388_11590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM388_11605	COG0596	Alpha beta hydrolase
KM388_11610	COG2814	Major facilitator Superfamily
KM388_11635	COG2226	methyltransferase
KM388_11680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_11715	COG1247	-acetyltransferase
KM388_11745	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM388_11755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_11765	COG1278	Cold shock
KM388_11780	COG0010	Belongs to the arginase family
KM388_11785	COG0561	phosphatase activity
KM388_11825	COG0583	DNA-binding transcription factor activity
KM388_11830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM388_11845	COG0583	DNA-binding transcription factor activity
KM388_11850	COG2258	MOSC domain
KM388_11865	COG1132	(ABC) transporter
KM388_11870	COG1132	(ABC) transporter
KM388_11890	COG1396	sequence-specific DNA binding
KM388_11915	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM388_11920	COG1595	DNA-templated transcription, initiation
KM388_11945	COG1649	PFAM Uncharacterised BCR, COG1649
KM388_11970	COG2971	BadF BadG BcrA BcrD
KM388_11975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM388_11980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM388_12000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_12030	COG1309	transcriptional regulator
KM388_12050	COG0577	efflux transmembrane transporter activity
KM388_12050	COG1136	(ABC) transporter
KM388_12055	COG0500	methyltransferase
KM388_12055	COG3615	Tellurite resistance protein tehB
KM388_12065	COG2226	methyltransferase
KM388_12070	COG3961	Belongs to the TPP enzyme family
KM388_12075	COG1846	Transcriptional regulator
KM388_12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM388_12130	COG1595	DNA-templated transcription, initiation
KM388_12140	COG0768	penicillin binding
KM388_12145	COG0768	penicillin binding
KM388_12150	COG2367	Beta-lactamase
KM388_12155	COG0671	phosphoesterase, PA-phosphatase related
KM388_12160	COG1609	Transcriptional regulator
KM388_12165	COG2814	Major facilitator Superfamily
KM388_12170	COG0673	inositol 2-dehydrogenase activity
KM388_12180	COG1012	belongs to the aldehyde dehydrogenase family
KM388_12195	COG0191	fructose-bisphosphate aldolase activity
KM388_12215	COG0737	Belongs to the 5'-nucleotidase family
KM388_12230	COG1476	TRANSCRIPTIONal
KM388_12245	COG1876	peptidase activity
KM388_12265	COG1309	transcriptional regulator
KM388_12270	COG0488	(ABC) transporter
KM388_12285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_12305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_12320	COG1131	(ABC) transporter
KM388_12330	COG1309	transcriptional regulator
KM388_12345	COG1960	acyl-CoA dehydrogenase activity
KM388_12350	COG0439	Biotin carboxylase
KM388_12355	COG0511	ligase activity, forming carbon-carbon bonds
KM388_12360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM388_12365	COG1024	Enoyl-CoA hydratase
KM388_12370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM388_12375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM388_12385	COG1247	-acetyltransferase
KM388_12390	COG0572	uridine kinase
KM388_12400	COG2318	DinB family
KM388_12405	COG1686	Belongs to the peptidase S11 family
KM388_12430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM388_12470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM388_12470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM388_12495	COG2814	Major facilitator Superfamily
KM388_12510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM388_12530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_12545	COG1063	alcohol dehydrogenase
KM388_12575	COG3773	Cell wall hydrolase
KM388_12585	COG0745	RESPONSE REGULATOR receiver
KM388_12600	COG0488	(ABC) transporter
KM388_12615	COG1136	(ABC) transporter
KM388_12640	COG0460	homoserine dehydrogenase
KM388_12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_12655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM388_12720	COG2124	cytochrome p450
KM388_12755	COG0561	phosphatase activity
KM388_12765	COG5002	protein histidine kinase activity
KM388_12770	COG0768	penicillin binding
KM388_12775	COG1819	glycosyl
KM388_12780	COG1794	racemase activity, acting on amino acids and derivatives
KM388_12790	COG1122	ATPase activity
KM388_12805	COG2205	protein histidine kinase activity
KM388_12815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM388_12820	COG0604	alcohol dehydrogenase
KM388_12825	COG0768	penicillin binding
KM388_12835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM388_12870	COG0693	protein deglycase activity
KM388_12900	COG2814	Major facilitator Superfamily
KM388_12915	COG0584	glycerophosphoryl diester phosphodiesterase
KM388_12935	COG0697	spore germination
KM388_12960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM388_12970	COG2223	nitrite transmembrane transporter activity
KM388_12985	COG2816	NAD+ diphosphatase activity
KM388_12990	COG0592	DNA-directed DNA polymerase activity
KM388_12995	COG1051	belongs to the nudix hydrolase family
KM388_13030	COG3878	Protein conserved in bacteria
KM388_13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM388_13090	COG0322	excinuclease ABC activity
KM388_13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM388_13155	COG1011	Hydrolase
KM388_13170	COG0657	acetylesterase activity
KM388_13175	COG0076	glutamate decarboxylase activity
KM388_13190	COG1523	belongs to the glycosyl hydrolase 13 family
KM388_13195	COG3227	Zinc metalloprotease (Elastase)
KM388_13215	COG0201	protein transport
KM388_13225	COG0697	spore germination
KM388_13230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_13260	COG4129	membrane
KM388_13265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_13280	COG2959	enzyme of heme biosynthesis
KM388_13300	COG3483	tryptophan 2,3-dioxygenase activity
KM388_13305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM388_13310	COG3844	kynureninase activity
KM388_13315	COG1309	transcriptional regulator
KM388_13345	COG3284	Transcriptional regulator
KM388_13365	COG1349	DNA-binding transcription factor activity
KM388_13385	COG1959	2 iron, 2 sulfur cluster binding
KM388_13400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM388_13405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM388_13410	COG0022	dehydrogenase e1 component
KM388_13415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM388_13425	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_13430	COG0456	acetyltransferase
KM388_13430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM388_13460	COG4176	ABC-type proline glycine betaine transport system permease component
KM388_13465	COG0517	IMP dehydrogenase activity
KM388_13465	COG4175	Glycine betaine
KM388_13490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM388_13495	COG2153	protein acetylation
KM388_13500	COG3397	chitin binding
KM388_13515	COG2205	protein histidine kinase activity
KM388_13540	COG0658	competence protein
KM388_13540	COG2333	competence protein COMEC
KM388_13590	COG3973	AAA domain
KM388_13605	COG2105	PFAM AIG2 family protein
KM388_13610	COG0514	ATP-dependent DNA helicase (RecQ)
KM388_13630	COG4637	Psort location Cytoplasmic, score
KM388_13655	COG3397	chitin binding
KM388_13670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM388_13675	COG1115	amino acid carrier protein
KM388_13680	COG1012	belongs to the aldehyde dehydrogenase family
KM388_13685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM388_13695	COG3938	Belongs to the proline racemase family
KM388_13700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM388_13740	COG0586	Pfam SNARE associated Golgi protein
KM388_13755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM388_13760	COG0519	Catalyzes the synthesis of GMP from XMP
KM388_13765	COG4166	transmembrane transport
KM388_13775	COG4948	Mandelate Racemase Muconate Lactonizing
KM388_13820	COG2936	dipeptidyl-peptidase activity
KM388_13825	COG5002	protein histidine kinase activity
KM388_13830	COG0745	RESPONSE REGULATOR receiver
KM388_13865	COG1164	Oligoendopeptidase f
KM388_13880	COG1307	EDD domain protein, DegV family
KM388_13900	COG2814	Major facilitator Superfamily
KM388_13910	COG1664	Polymer-forming cytoskeletal
KM388_13915	COG0789	Transcriptional regulator
KM388_13920	COG4533	DNA binding
KM388_13925	COG0477	Major facilitator Superfamily
KM388_13925	COG2814	Major facilitator Superfamily
KM388_13945	COG2261	transglycosylase associated protein
KM388_13960	COG2226	methyltransferase
KM388_13995	COG0436	Aminotransferase
KM388_14000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM388_14005	COG5146	pantothenate kinase activity
KM388_14025	COG1131	(ABC) transporter
KM388_14070	COG0628	permease
KM388_14080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM388_14085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM388_14090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM388_14095	COG1116	anion transmembrane transporter activity
KM388_14115	COG2816	NAD+ diphosphatase activity
KM388_14135	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM388_14160	COG0697	spore germination
KM388_14165	COG2318	DinB family
KM388_14205	COG0861	Integral membrane protein TerC family
KM388_14210	COG1368	sulfuric ester hydrolase activity
KM388_14215	COG0488	(ABC) transporter
KM388_14230	COG1309	transcriptional regulator
KM388_14245	COG0287	Prephenate dehydrogenase
KM388_14250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM388_14255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM388_14260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM388_14260	COG1605	Chorismate mutase
KM388_14295	COG3584	3D domain protein
KM388_14295	COG1388	LysM domain
KM388_14305	COG1595	DNA-templated transcription, initiation
KM388_14330	COG1879	ABC-type sugar transport system periplasmic component
KM388_14340	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM388_14350	COG2390	Transcriptional regulator
KM388_14355	COG1070	Carbohydrate kinase
KM388_14385	COG2329	Antibiotic biosynthesis monooxygenase
KM388_14405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_14415	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM388_14420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM388_14425	COG4187	Peptidase family M20/M25/M40
KM388_14430	COG1414	Transcriptional regulator
KM388_14435	COG0833	amino acid
KM388_14440	COG1690	Belongs to the RtcB family
KM388_14445	COG3239	Fatty acid desaturase
KM388_14450	COG1785	Belongs to the alkaline phosphatase family
KM388_14460	COG3655	Transcriptional regulator
KM388_14475	COG4377	Putative membrane peptidase family (DUF2324)
KM388_14485	COG3279	Response regulator of the LytR AlgR family
KM388_14495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_14500	COG0346	lactoylglutathione lyase activity
KM388_14520	COG0714	Associated with various cellular activities
KM388_14570	COG0463	Glycosyl transferase, family 2
KM388_14580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM388_14585	COG0753	catalase activity
KM388_14595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM388_14620	COG0714	Associated with various cellular activities
KM388_14630	COG0778	Nitroreductase
KM388_14635	COG1846	Transcriptional regulator
KM388_14670	COG1725	Transcriptional regulator
KM388_14680	COG0577	efflux transmembrane transporter activity
KM388_14680	COG1136	(ABC) transporter
KM388_14705	COG2207	Transcriptional regulator
KM388_14710	COG0456	acetyltransferase
KM388_14730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_14750	COG0642	Histidine kinase
KM388_14755	COG0745	RESPONSE REGULATOR receiver
KM388_14760	COG0596	Alpha beta hydrolase
KM388_14790	COG0730	response to heat
KM388_14800	COG0833	amino acid
KM388_14810	COG4335	DNA alkylation repair
KM388_14850	COG0768	penicillin binding
KM388_14860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM388_14890	COG1984	allophanate hydrolase subunit 2
KM388_14895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM388_14900	COG1414	Transcriptional regulator
KM388_14915	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM388_14920	COG0640	Transcriptional regulator
KM388_14930	COG1960	acyl-CoA dehydrogenase activity
KM388_14945	COG3314	Sporulation integral membrane protein YlbJ
KM388_14960	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM388_14975	COG0574	Belongs to the PEP-utilizing enzyme family
KM388_14975	COG3848	Pyruvate phosphate dikinase
KM388_14980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_14995	COG5577	PFAM Coat F domain
KM388_15000	COG3403	YqcI/YcgG family
KM388_15005	COG1280	lysine exporter protein (LysE YggA)
KM388_15040	COG1063	alcohol dehydrogenase
KM388_15055	COG1027	Aspartate ammonia-lyase
KM388_15060	COG0252	asparaginase activity
KM388_15065	COG1396	sequence-specific DNA binding
KM388_15075	COG0322	excinuclease ABC activity
KM388_15080	COG0531	amino acid
KM388_15085	COG1114	Component of the transport system for branched-chain amino acids
KM388_15090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM388_15100	COG0281	malic enzyme
KM388_15115	COG0531	amino acid
KM388_15125	COG0784	Response regulator, receiver
KM388_15135	COG2066	Belongs to the glutaminase family
KM388_15140	COG1115	amino acid carrier protein
KM388_15170	COG0737	Belongs to the 5'-nucleotidase family
KM388_15175	COG0753	catalase activity
KM388_15180	COG2267	carboxylic ester hydrolase activity
KM388_15185	COG1335	isochorismatase
KM388_15205	COG0583	DNA-binding transcription factor activity
KM388_15210	COG1846	Transcriptional regulator
KM388_15215	COG0598	Magnesium transport protein CorA
KM388_15250	COG0415	Belongs to the DNA photolyase family
KM388_15255	COG0288	reversible hydration of carbon dioxide
KM388_15265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM388_15270	COG5609	conserved protein (DUF2294)
KM388_15285	COG1575	Belongs to the MenA family. Type 1 subfamily
KM388_15290	COG2267	carboxylic ester hydrolase activity
KM388_15295	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM388_15300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM388_15305	COG1121	(ABC) transporter
KM388_15335	COG0798	PFAM Bile acid sodium symporter
KM388_15340	COG0346	lactoylglutathione lyase activity
KM388_15345	COG0640	Transcriptional regulator
KM388_15360	COG0443	Heat shock 70 kDa protein
KM388_15375	COG1522	sequence-specific DNA binding
KM388_15390	COG0346	lactoylglutathione lyase activity
KM388_15410	COG2169	Transcriptional regulator
KM388_15455	COG2814	Major facilitator Superfamily
KM388_15480	COG0745	RESPONSE REGULATOR receiver
KM388_15485	COG5002	protein histidine kinase activity
KM388_15485	COG3850	Histidine kinase
KM388_15510	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM388_15530	COG1476	TRANSCRIPTIONal
KM388_15545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_15550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM388_15560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_15565	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM388_15580	COG1136	(ABC) transporter
KM388_15585	COG0577	efflux transmembrane transporter activity
KM388_15600	COG5002	protein histidine kinase activity
KM388_15600	COG3850	Histidine kinase
KM388_15610	COG2364	Membrane
KM388_15615	COG1846	Transcriptional regulator
KM388_15625	COG2808	Putative FMN-binding domain
KM388_15630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_15635	COG2271	Major facilitator Superfamily
KM388_15640	COG1556	Lactate utilization protein
KM388_15645	COG1139	Iron-sulfur cluster binding protein
KM388_15665	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM388_15690	COG0673	inositol 2-dehydrogenase activity
KM388_15695	COG0561	phosphatase activity
KM388_15705	COG1609	Transcriptional regulator
KM388_15710	COG0457	Tetratricopeptide repeat
KM388_15760	COG0534	Mate efflux family protein
KM388_15780	COG2814	Major facilitator Superfamily
KM388_15785	COG1309	transcriptional regulator
KM388_15800	COG0814	amino acid
KM388_15805	COG1760	l-serine dehydratase
KM388_15810	COG1760	l-serine dehydratase
KM388_15820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM388_15825	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM388_15840	COG1522	sequence-specific DNA binding
KM388_15845	COG0531	amino acid
KM388_15860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM388_15880	COG1595	DNA-templated transcription, initiation
KM388_15895	COG0662	Cupin 2, conserved barrel domain protein
KM388_15900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_15900	COG2207	Transcriptional regulator
KM388_15950	COG0477	Major facilitator Superfamily
KM388_15960	COG1846	Transcriptional regulator
KM388_15965	COG2814	Major facilitator Superfamily
KM388_15975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM388_15980	COG1131	(ABC) transporter
KM388_16000	COG2076	Multidrug Resistance protein
KM388_16005	COG1309	transcriptional regulator
KM388_16015	COG2031	fatty acid transporter
KM388_16025	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM388_16055	COG1122	ATPase activity
KM388_16060	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM388_16075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM388_16080	COG1288	antiporter activity
KM388_16085	COG2356	endonuclease I
KM388_16100	COG3620	sequence-specific DNA binding
KM388_16105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM388_16110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM388_16115	COG0124	histidyl-tRNA synthetase
KM388_16130	COG1733	regulation of RNA biosynthetic process
KM388_16135	COG0778	Nitroreductase
KM388_16155	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_16165	COG1131	(ABC) transporter
KM388_16190	COG1011	Hydrolase
KM388_16200	COG2365	Tyrosine phosphatase family
KM388_16225	COG0346	lactoylglutathione lyase activity
KM388_16230	COG1940	carbohydrate kinase activity
KM388_16235	COG0738	Major facilitator superfamily
KM388_16240	COG0110	maltose O-acetyltransferase activity
KM388_16250	COG0577	efflux transmembrane transporter activity
KM388_16250	COG1136	(ABC) transporter
KM388_16265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM388_16270	COG0628	permease
KM388_16290	COG2226	methyltransferase
KM388_16300	COG0477	Major facilitator Superfamily
KM388_16330	COG1253	flavin adenine dinucleotide binding
KM388_16335	COG0789	Transcriptional regulator
KM388_16340	COG0697	spore germination
KM388_16345	COG1357	PFAM Pentapeptide repeats (8 copies)
KM388_16350	COG3813	Protein conserved in bacteria
KM388_16355	COG2706	6-phosphogluconolactonase activity
KM388_16360	COG1070	Carbohydrate kinase
KM388_16370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM388_16375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM388_16390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM388_16395	COG0604	alcohol dehydrogenase
KM388_16400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM388_16410	COG0604	alcohol dehydrogenase
KM388_16410	COG3321	synthase
KM388_16415	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_16440	COG0656	L-ascorbic acid biosynthetic process
KM388_16445	COG2814	Major facilitator Superfamily
KM388_16460	COG0346	lactoylglutathione lyase activity
KM388_16465	COG0814	amino acid
KM388_16490	COG1393	Belongs to the ArsC family
KM388_16495	COG1733	regulation of RNA biosynthetic process
KM388_16500	COG2188	Transcriptional regulator
KM388_16505	COG0673	inositol 2-dehydrogenase activity
KM388_16510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM388_16515	COG1733	regulation of RNA biosynthetic process
KM388_16520	COG1733	regulation of RNA biosynthetic process
KM388_16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_16555	COG0384	phenazine biosynthesis protein PhzF
KM388_16565	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_16575	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_16585	COG1733	regulation of RNA biosynthetic process
KM388_16620	COG1191	sigma factor activity
KM388_16635	COG1309	transcriptional regulator
KM388_16655	COG3152	Membrane
KM388_16680	COG1151	hydroxylamine reductase activity
KM388_16690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_16695	COG3757	hydrolase, family 25
KM388_16695	COG3409	Peptidoglycan-binding domain 1 protein
KM388_16730	COG2072	flavoprotein involved in K transport
KM388_16765	COG0604	alcohol dehydrogenase
KM388_16770	COG1113	amino acid transport
KM388_16775	COG2814	Major facilitator Superfamily
KM388_16805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM388_16810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM388_16830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_16835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_16840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_16845	COG3739	integral membrane protein
KM388_16850	COG0384	phenazine biosynthesis protein PhzF
KM388_16880	COG0583	DNA-binding transcription factor activity
KM388_16900	COG1193	negative regulation of DNA recombination
KM388_16915	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM388_16920	COG1164	Oligoendopeptidase f
KM388_16925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM388_16955	COG0584	glycerophosphoryl diester phosphodiesterase
KM388_16980	COG0640	Transcriptional regulator
KM388_16985	COG0604	alcohol dehydrogenase
KM388_17005	COG2808	Putative FMN-binding domain
KM388_17020	COG0385	Bile acid
KM388_17025	COG0277	FAD linked oxidase domain protein
KM388_17055	COG1216	Glycosyl transferase, family 2
KM388_17060	COG1024	Enoyl-CoA hydratase
KM388_17070	COG1285	pathogenesis
KM388_17085	COG2514	catechol 2,3-dioxygenase activity
KM388_17090	COG2720	vancomycin resistance protein
KM388_17130	COG0716	FMN binding
KM388_17160	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_17185	COG4145	pantothenate transmembrane transporter activity
KM388_17195	COG1012	belongs to the aldehyde dehydrogenase family
KM388_17200	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_17210	COG1657	PFAM Prenyltransferase squalene oxidase
KM388_17215	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM388_17220	COG2962	Rard protein
KM388_17225	COG3326	Membrane
KM388_17240	COG0489	protein tyrosine kinase activity
KM388_17250	COG0314	molybdopterin synthase activity
KM388_17255	COG0303	'Molybdopterin
KM388_17260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM388_17265	COG2116	formate transmembrane transporter activity
KM388_17275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM388_17280	COG5609	conserved protein (DUF2294)
KM388_17285	COG2427	Protein of unknown function (DUF1641)
KM388_17295	COG0697	spore germination
KM388_17335	COG2226	methyltransferase
KM388_17340	COG4166	transmembrane transport
KM388_17345	COG4166	transmembrane transport
KM388_17350	COG1301	dicarboxylic acid transport
KM388_17355	COG1316	TRANSCRIPTIONal
KM388_17365	COG1595	DNA-templated transcription, initiation
KM388_17385	COG1131	(ABC) transporter
KM388_17395	COG0673	inositol 2-dehydrogenase activity
KM388_17400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM388_17405	COG0187	DNA topoisomerase II activity
KM388_17410	COG1832	CoA-binding protein
KM388_17415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM388_17420	COG0745	RESPONSE REGULATOR receiver
KM388_17435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM388_17440	COG4841	protein insertion into membrane
KM388_17445	COG0824	Thioesterase
KM388_17475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM388_17485	COG2274	protein secretion by the type I secretion system
KM388_17490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM388_17530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM388_17545	COG0183	Belongs to the thiolase family
KM388_17550	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_17555	COG1268	BioY protein
KM388_17560	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_17610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_17620	COG5002	protein histidine kinase activity
KM388_17625	COG0400	carboxylic ester hydrolase activity
KM388_17630	COG0346	lactoylglutathione lyase activity
KM388_17635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM388_17640	COG0069	glutamate synthase activity
KM388_17645	COG1902	pentaerythritol trinitrate reductase activity
KM388_17650	COG1329	Transcriptional regulator
KM388_17655	COG0010	Belongs to the arginase family
KM388_17680	COG2226	methyltransferase
KM388_17735	COG4846	Membrane protein involved in cytochrome C biogenesis
KM388_17740	COG0785	Cytochrome C biogenesis protein
KM388_17750	COG0583	DNA-binding transcription factor activity
KM388_17755	COG1380	Effector of murein hydrolase LrgA
KM388_17760	COG1346	cytolysis
KM388_17785	COG3409	Peptidoglycan-binding domain 1 protein
KM388_17785	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM388_17800	COG1132	(ABC) transporter
KM388_17805	COG1132	(ABC) transporter
KM388_17835	COG3639	organic phosphonate transmembrane transporter activity
KM388_17840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM388_17860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM388_17880	COG1695	Transcriptional regulator
KM388_17915	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM388_17915	COG3409	Peptidoglycan-binding domain 1 protein
KM388_17915	COG1388	LysM domain
KM388_17920	COG4824	toxin secretion phage lysis holin
KM388_18065	COG1595	DNA-templated transcription, initiation
KM388_18110	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM388_18190	COG1396	sequence-specific DNA binding
KM388_18215	COG0174	glutamine synthetase
KM388_18220	COG0789	Transcriptional regulator
KM388_18225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM388_18230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM388_18235	COG2860	membrane
KM388_18240	COG0464	growth
KM388_18270	COG1388	LysM domain
KM388_18270	COG3584	3D domain protein
KM388_18275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM388_18275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM388_18275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM388_18280	COG1105	Belongs to the carbohydrate kinase PfkB family
KM388_18285	COG1349	DNA-binding transcription factor activity
KM388_18295	COG2322	membrane
KM388_18305	COG1113	amino acid transport
KM388_18320	COG1408	metallophosphoesterase
KM388_18325	COG2116	formate transmembrane transporter activity
KM388_18335	COG2217	Heavy metal translocating P-type atpase
KM388_18340	COG2608	mercury ion transmembrane transporter activity
KM388_18345	COG1937	Protein conserved in bacteria
KM388_18355	COG2819	hydrolase of the alpha beta superfamily
KM388_18360	COG1120	ATPase activity
KM388_18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_18370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_18385	COG2169	Transcriptional regulator
KM388_18390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM388_18395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM388_18405	COG2364	Membrane
KM388_18420	COG2267	carboxylic ester hydrolase activity
KM388_18425	COG0346	lactoylglutathione lyase activity
KM388_18445	COG1346	cytolysis
KM388_18450	COG1380	Effector of murein hydrolase LrgA
KM388_18455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM388_18460	COG0596	Alpha beta hydrolase
KM388_18460	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM388_18465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM388_18485	COG1404	Belongs to the peptidase S8 family
KM388_18490	COG3773	Cell wall hydrolase
KM388_18495	COG0562	UDP-galactopyranose mutase
KM388_18500	COG1368	sulfuric ester hydrolase activity
KM388_18505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM388_18515	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM388_18540	COG1131	(ABC) transporter
KM388_18560	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM388_18565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM388_18570	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM388_18575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM388_18575	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM388_18585	COG2359	stage V sporulation protein S
KM388_18590	COG1692	metallophosphoesterase
KM388_18615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM388_18620	COG1426	Protein conserved in bacteria
KM388_18635	COG0300	oxidoreductase activity
KM388_18640	COG0612	Peptidase, M16
KM388_18645	COG0612	Peptidase, M16
KM388_18650	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM388_18660	COG3845	ABC transporter
KM388_18665	COG1744	ABC transporter substrate-binding protein PnrA-like
KM388_18670	COG2188	Transcriptional regulator
KM388_18675	COG1674	ftsk spoiiie
KM388_18685	COG0740	serine-type endopeptidase activity
KM388_18690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM388_18700	COG0527	aspartate kinase activity
KM388_18705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM388_18710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM388_18715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM388_18720	COG1873	PFAM PRC-barrel domain
KM388_18725	COG0612	Peptidase, M16
KM388_18730	COG0726	polysaccharide deacetylase
KM388_18745	COG0196	riboflavin kinase activity
KM388_18750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM388_18760	COG1550	Protein conserved in bacteria
KM388_18770	COG1358	cellular component organization or biogenesis
KM388_18775	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM388_18780	COG0195	Participates in both transcription termination and antitermination
KM388_18800	COG0750	zinc metalloprotease
KM388_18810	COG4589	Belongs to the CDS family
KM388_18825	COG0528	UMP kinase activity
KM388_18855	COG4974	Belongs to the 'phage' integrase family
KM388_18865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM388_18875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM388_18915	COG1837	Belongs to the UPF0109 family
KM388_18925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM388_18935	COG0552	protein localization to endoplasmic reticulum
KM388_18940	COG1196	nuclear chromosome segregation
KM388_18950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM388_18955	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_18960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM388_18975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM388_18980	COG1461	Dihydroxyacetone kinase
KM388_18985	COG1302	Protein conserved in bacteria
KM388_19000	COG1564	THIamine pyrophosphokinase
KM388_19005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM388_19010	COG1162	GTPase activity
KM388_19015	COG0515	serine threonine protein kinase
KM388_19015	COG2815	serine threonine protein kinase
KM388_19020	COG0631	protein serine/threonine phosphatase activity
KM388_19030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM388_19030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM388_19040	COG0242	peptide deformylase activity
KM388_19045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM388_19050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM388_19070	COG1561	YicC-like family, N-terminal region
KM388_19075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM388_19085	COG0006	proline dipeptidase activity
KM388_19100	COG3069	C4-dicarboxylate transmembrane transporter activity
KM388_19165	COG0564	pseudouridine synthase activity
KM388_19185	COG3599	regulation of cell shape
KM388_19190	COG2302	S4 RNA-binding domain
KM388_19195	COG0762	integral membrane protein
KM388_19205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM388_19210	COG1496	oxidoreductase activity
KM388_19215	COG1873	PFAM PRC-barrel domain
KM388_19220	COG1191	sigma factor activity
KM388_19225	COG1191	sigma factor activity
KM388_19235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM388_19240	COG0849	cell division
KM388_19245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM388_19250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM388_19260	COG0772	Belongs to the SEDS family
KM388_19275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM388_19280	COG0768	penicillin binding
KM388_19285	COG0768	penicillin binding
KM388_19290	COG4839	cell division protein FtsL
KM388_19305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM388_19320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM388_19325	COG1399	metal-binding, possibly nucleic acid-binding protein
KM388_19375	COG4824	toxin secretion phage lysis holin
KM388_19460	COG4626	Terminase
KM388_19460	COG1802	Transcriptional regulator
KM388_19485	COG0582	viral genome integration into host DNA
KM388_19550	COG0756	dUTP diphosphatase activity
KM388_19590	COG1484	DNA-dependent DNA replication
KM388_19615	COG1396	sequence-specific DNA binding
KM388_19630	COG1396	sequence-specific DNA binding
KM388_19645	COG0582	viral genome integration into host DNA
KM388_19655	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM388_19660	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM388_19665	COG3314	Sporulation integral membrane protein YlbJ
KM388_19675	COG0742	ribosomal rna small subunit methyltransferase
KM388_19690	COG3679	Belongs to the UPF0342 family
KM388_19695	COG0406	alpha-ribazole phosphatase activity
KM388_19710	COG2340	Cysteine-rich secretory protein family
KM388_19725	COG3336	cytochrome c oxidase
KM388_19760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM388_19765	COG0772	Belongs to the SEDS family
KM388_19775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM388_19780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM388_19790	COG4896	Protein conserved in bacteria
KM388_19805	COG1217	gtp-binding protein TYPA
KM388_19815	COG0483	inositol monophosphate 1-phosphatase activity
KM388_19835	COG1982	Orn Lys Arg decarboxylase major
KM388_19885	COG0022	dehydrogenase e1 component
KM388_19890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM388_19900	COG0242	peptide deformylase activity
KM388_19915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM388_19920	COG0569	domain protein
KM388_19940	COG0583	DNA-binding transcription factor activity
KM388_19945	COG0517	IMP dehydrogenase activity
KM388_19955	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM388_19965	COG4703	Protein of unknown function (DUF1797)
KM388_19980	COG2200	EAL domain
KM388_19985	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_19990	COG1408	metallophosphoesterase
KM388_20035	COG2814	Major facilitator Superfamily
KM388_20055	COG3209	COG3209 Rhs family protein
KM388_20065	COG2205	protein histidine kinase activity
KM388_20075	COG0436	Aminotransferase
KM388_20080	COG1609	Transcriptional regulator
KM388_20085	COG3833	ABC-type maltose transport systems, permease component
KM388_20090	COG1175	transmembrane transport
KM388_20095	COG2182	Extracellular solute-binding protein
KM388_20105	COG0366	Alpha amylase catalytic
KM388_20110	COG3842	ATPase activity
KM388_20150	COG0183	Belongs to the thiolase family
KM388_20185	COG1695	Transcriptional regulator
KM388_20190	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_20200	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM388_20210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM388_20215	COG0436	Aminotransferase
KM388_20235	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM388_20255	COG2199	diguanylate cyclase activity
KM388_20260	COG0778	Nitroreductase
KM388_20285	COG1263	PTS System
KM388_20285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM388_20285	COG2190	(PTS) system
KM388_20290	COG3711	transcriptional antiterminator
KM388_20300	COG2188	Transcriptional regulator
KM388_20310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM388_20335	COG1547	Domain of unknown function (DUF309)
KM388_20340	COG0456	acetyltransferase
KM388_20345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM388_20350	COG4086	secreted protein
KM388_20355	COG0561	phosphatase activity
KM388_20360	COG0697	spore germination
KM388_20375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_20400	COG0733	neurotransmitter:sodium symporter activity
KM388_20420	COG1686	Belongs to the peptidase S11 family
KM388_20425	COG1725	Transcriptional regulator
KM388_20430	COG1131	(ABC) transporter
KM388_20445	COG1846	Transcriptional regulator
KM388_20460	COG0598	Magnesium transport protein CorA
KM388_20485	COG4974	Belongs to the 'phage' integrase family
KM388_20495	COG0735	belongs to the Fur family
KM388_20500	COG1300	Membrane
KM388_20520	COG0667	Aldo Keto reductase
KM388_20525	COG0656	L-ascorbic acid biosynthetic process
KM388_20530	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM388_20530	COG0456	acetyltransferase
KM388_20540	COG0737	Belongs to the 5'-nucleotidase family
KM388_20540	COG1525	nuclease
KM388_20540	COG4085	toxin activity
KM388_20550	COG0596	Alpha beta hydrolase
KM388_20555	COG2056	Na+-H+ antiporter family
KM388_20560	COG1609	Transcriptional regulator
KM388_20565	COG0456	acetyltransferase
KM388_20570	COG1073	alpha beta
KM388_20585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM388_20585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM388_20590	COG0307	riboflavin synthase, alpha
KM388_20615	COG4106	trans-aconitate 2-methyltransferase activity
KM388_20620	COG2226	methyltransferase
KM388_20620	COG1073	alpha beta
KM388_20635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM388_20645	COG1757	Na H antiporter
KM388_20650	COG0737	Belongs to the 5'-nucleotidase family
KM388_20660	COG1522	sequence-specific DNA binding
KM388_20680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM388_20690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM388_20705	COG0300	oxidoreductase activity
KM388_20710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_20715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM388_20720	COG1760	l-serine dehydratase
KM388_20725	COG1760	l-serine dehydratase
KM388_20745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM388_20755	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM388_20760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_20775	COG1376	ErfK ybiS ycfS ynhG family protein
KM388_20780	COG4129	membrane
KM388_20785	COG1126	abc transporter atp-binding protein
KM388_20790	COG0765	amino acid transport
KM388_20795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM388_20810	COG2816	NAD+ diphosphatase activity
KM388_20815	COG0772	Belongs to the SEDS family
KM388_20820	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM388_20825	COG0022	dehydrogenase e1 component
KM388_20830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM388_20835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM388_20850	COG0280	phosphate acetyltransferase
KM388_20855	COG3290	protein histidine kinase activity
KM388_20855	COG3829	transcription factor binding
KM388_20865	COG0584	glycerophosphoryl diester phosphodiesterase
KM388_20870	COG3093	addiction module antidote protein HigA
KM388_20880	COG0745	RESPONSE REGULATOR receiver
KM388_20885	COG0750	zinc metalloprotease
KM388_20890	COG0497	DNA recombination
KM388_20900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM388_20910	COG0142	geranyltranstransferase activity
KM388_20935	COG1302	Protein conserved in bacteria
KM388_20940	COG0439	Biotin carboxylase
KM388_20945	COG0511	ligase activity, forming carbon-carbon bonds
KM388_20990	COG3854	ATPases associated with a variety of cellular activities
KM388_21015	COG0006	proline dipeptidase activity
KM388_21030	COG3872	metal-dependent enzyme
KM388_21040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM388_21060	COG0095	Lipoate-protein ligase
KM388_21065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_21070	COG1609	Transcriptional regulator
KM388_21080	COG2076	Multidrug Resistance protein
KM388_21085	COG2076	Multidrug Resistance protein
KM388_21120	COG1131	(ABC) transporter
KM388_21125	COG1725	Transcriptional regulator
KM388_21155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM388_21210	COG4970	Tfp pilus assembly protein FimT
KM388_21215	COG4537	Required for transformation and DNA binding
KM388_21220	COG1459	type II secretion system
KM388_21225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM388_21275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM388_21285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM388_21285	COG0646	methionine synthase
KM388_21290	COG0626	cystathionine gamma-synthase activity
KM388_21295	COG0626	cystathionine gamma-synthase activity
KM388_21315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_21325	COG1940	carbohydrate kinase activity
KM388_21330	COG4483	Protein conserved in bacteria
KM388_21335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM388_21340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM388_21345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM388_21350	COG0704	Plays a role in the regulation of phosphate uptake
KM388_21360	COG0581	inorganic phosphate transmembrane transporter activity
KM388_21365	COG0573	inorganic phosphate transmembrane transporter activity
KM388_21370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM388_21375	COG0768	penicillin binding
KM388_21380	COG0477	Major facilitator Superfamily
KM388_21385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM388_21410	COG0735	belongs to the Fur family
KM388_21415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM388_21420	COG1121	(ABC) transporter
KM388_21425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_21455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM388_21460	COG2384	SAM-dependent methyltransferase
KM388_21465	COG2010	Cytochrome c
KM388_21470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM388_21475	COG0358	DNA primase activity
KM388_21485	COG0517	IMP dehydrogenase activity
KM388_21500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM388_21505	COG0295	cytidine deaminase activity
KM388_21510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM388_21520	COG1480	7TM receptor with intracellular HD hydrolase
KM388_21525	COG1702	phosphate starvation-inducible protein PhoH
KM388_21540	COG1610	YqeY-like protein
KM388_21545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM388_21550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM388_21555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM388_21585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM388_21590	COG1733	regulation of RNA biosynthetic process
KM388_21615	COG1466	dna polymerase III delta subunit
KM388_21630	COG2131	deaminase
KM388_21635	COG1596	polysaccharide export
KM388_21635	COG1555	photosystem II stabilization
KM388_21640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM388_21645	COG2226	methyltransferase
KM388_21650	COG0799	negative regulation of ribosome biogenesis
KM388_21655	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM388_21665	COG1534	Rna-binding protein
KM388_21675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM388_21680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM388_21705	COG1595	DNA-templated transcription, initiation
KM388_21715	COG0778	Nitroreductase
KM388_21720	COG2357	RelA SpoT domain protein
KM388_21730	COG1785	Belongs to the alkaline phosphatase family
KM388_21740	COG2267	carboxylic ester hydrolase activity
KM388_21775	COG1404	Belongs to the peptidase S8 family
KM388_21780	COG3186	Phenylalanine-4-hydroxylase
KM388_21790	COG2514	catechol 2,3-dioxygenase activity
KM388_21795	COG2259	Doxx family
KM388_21835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_21845	COG1454	alcohol dehydrogenase
KM388_21845	COG1012	belongs to the aldehyde dehydrogenase family
KM388_21850	COG0626	cystathionine gamma-synthase activity
KM388_21855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM388_21880	COG0768	penicillin binding
KM388_21895	COG0826	peptidase U32
KM388_21900	COG0826	peptidase U32
KM388_21905	COG4122	O-methyltransferase activity
KM388_21910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM388_21930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM388_21940	COG0628	permease
KM388_21960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM388_21970	COG0482	sulfurtransferase activity
KM388_21975	COG1104	cysteine desulfurase activity
KM388_21980	COG1959	2 iron, 2 sulfur cluster binding
KM388_21985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM388_21995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM388_22020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM388_22030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM388_22030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM388_22035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM388_22040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM388_22040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM388_22050	COG2244	polysaccharide biosynthetic process
KM388_22055	COG2323	membrane
KM388_22065	COG1862	Preprotein translocase
KM388_22095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM388_22105	COG0697	spore germination
KM388_22110	COG0697	spore germination
KM388_22115	COG0640	Transcriptional regulator
KM388_22140	COG0157	Belongs to the NadC ModD family
KM388_22145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM388_22150	COG1104	cysteine desulfurase activity
KM388_22155	COG1827	regulation of RNA biosynthetic process
KM388_22160	COG2258	MOSC domain
KM388_22165	COG0077	Prephenate dehydratase
KM388_22170	COG0577	efflux transmembrane transporter activity
KM388_22175	COG0577	efflux transmembrane transporter activity
KM388_22180	COG1136	(ABC) transporter
KM388_22195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM388_22200	COG3290	protein histidine kinase activity
KM388_22210	COG2868	ribosomal protein
KM388_22220	COG1530	ribonuclease E activity
KM388_22225	COG1994	Peptidase M50
KM388_22230	COG0739	heme binding
KM388_22235	COG2894	cell division
KM388_22255	COG1077	Cell shape determining protein MreB Mrl
KM388_22275	COG0285	dihydrofolate synthase activity
KM388_22280	COG0525	valine-tRNA ligase activity
KM388_22290	COG1388	LysM domain
KM388_22300	COG0113	porphobilinogen synthase activity
KM388_22305	COG1587	Uroporphyrinogen-III synthase
KM388_22315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM388_22325	COG1846	Transcriptional regulator
KM388_22330	COG1764	response to oxidative stress
KM388_22345	COG0470	DNA polymerase III
KM388_22345	COG1067	ATP-dependent peptidase activity
KM388_22390	COG0622	Phosphoesterase
KM388_22405	COG5401	PFAM Sporulation and spore germination
KM388_22425	COG1309	transcriptional regulator
KM388_22440	COG2197	response regulator
KM388_22445	COG2233	PERMEase
KM388_22455	COG0402	S-adenosylhomocysteine deaminase activity
KM388_22460	COG0402	S-adenosylhomocysteine deaminase activity
KM388_22470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM388_22480	COG0444	Belongs to the ABC transporter superfamily
KM388_22485	COG4608	Belongs to the ABC transporter superfamily
KM388_22490	COG3275	phosphorelay sensor kinase activity
KM388_22495	COG3279	Response regulator of the LytR AlgR family
KM388_22510	COG1983	PspC domain protein
KM388_22515	COG1396	sequence-specific DNA binding
KM388_22520	COG0697	spore germination
KM388_22530	COG1959	2 iron, 2 sulfur cluster binding
KM388_22535	COG1668	transmembrane transport
KM388_22545	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM388_22555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM388_22560	COG1876	peptidase activity
KM388_22565	COG0824	Thioesterase
KM388_22570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM388_22575	COG1053	succinate dehydrogenase
KM388_22580	COG2009	succinate dehydrogenase
KM388_22585	COG1719	4-vinyl reductase, 4VR
KM388_22595	COG3118	belongs to the thioredoxin family
KM388_22600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM388_22605	COG2086	electron transfer activity
KM388_22610	COG1024	Enoyl-CoA hydratase
KM388_22615	COG1309	transcriptional regulator
KM388_22620	COG0318	PFAM AMP-dependent synthetase and ligase
KM388_22640	COG2318	DinB family
KM388_22670	COG1131	(ABC) transporter
KM388_22675	COG2205	protein histidine kinase activity
KM388_22680	COG0745	RESPONSE REGULATOR receiver
KM388_22690	COG4895	conserved protein (DUF2196)
KM388_22695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM388_22710	COG4509	Sortase family
KM388_22715	COG1120	ATPase activity
KM388_22730	COG5386	Cell surface protein
KM388_22740	COG5386	Cell surface protein
KM388_22745	COG1114	Component of the transport system for branched-chain amino acids
KM388_22750	COG1187	pseudouridine synthase activity
KM388_22760	COG1796	DNA polymerase
KM388_22760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM388_22765	COG1286	toxin biosynthetic process
KM388_22810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM388_22820	COG1418	mRNA catabolic process
KM388_22845	COG2814	Major facilitator Superfamily
KM388_22850	COG1566	PFAM secretion protein HlyD family protein
KM388_22855	COG1309	transcriptional regulator
KM388_22860	COG1363	Peptidase, m42
KM388_22885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM388_22895	COG1484	DNA-dependent DNA replication
KM388_22900	COG3611	Membrane attachment protein
KM388_22910	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM388_22915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM388_22920	COG0237	dephospho-CoA kinase activity
KM388_22925	COG1971	Probably functions as a manganese efflux pump
KM388_22935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM388_22935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM388_22940	COG5002	protein histidine kinase activity
KM388_22945	COG0745	RESPONSE REGULATOR receiver
KM388_22965	COG0538	isocitrate dehydrogenase activity
KM388_22970	COG0372	Belongs to the citrate synthase family
KM388_22980	COG0628	permease
KM388_22985	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM388_23010	COG1725	Transcriptional regulator
KM388_23015	COG0281	malic enzyme
KM388_23020	COG0587	DNA-directed DNA polymerase activity
KM388_23035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM388_23055	COG4109	DRTGG domain
KM388_23070	COG0006	proline dipeptidase activity
KM388_23105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_23110	COG0662	Cupin 2, conserved barrel domain protein
KM388_23120	COG1476	TRANSCRIPTIONal
KM388_23135	COG1028	Short-chain dehydrogenase reductase Sdr
KM388_23140	COG0589	response to stress
KM388_23180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_23200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM388_23205	COG0827	DNA restriction-modification system
KM388_23210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM388_23215	COG3874	Sporulation protein YtfJ
KM388_23230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM388_23240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM388_23255	COG1104	cysteine desulfurase activity
KM388_23265	COG0583	DNA-binding transcription factor activity
KM388_23270	COG0697	spore germination
KM388_23280	COG1956	GAF domain-containing protein
KM388_23285	COG0626	cystathionine gamma-synthase activity
KM388_23315	COG1595	DNA-templated transcription, initiation
KM388_23325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM388_23330	COG0454	-acetyltransferase
KM388_23335	COG0517	IMP dehydrogenase activity
KM388_23340	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM388_23350	COG0745	RESPONSE REGULATOR receiver
KM388_23360	COG0666	response to abiotic stimulus
KM388_23395	COG1609	Transcriptional regulator
KM388_23400	COG4851	CamS sex pheromone cAM373 precursor
KM388_23405	COG3118	belongs to the thioredoxin family
KM388_23415	COG2309	aminopeptidase activity
KM388_23435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_23450	COG1674	ftsk spoiiie
KM388_23460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM388_23465	COG4848	Belongs to the UPF0354 family
KM388_23470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM388_23475	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM388_23480	COG1363	Peptidase, m42
KM388_23490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_23505	COG0510	thiamine kinase activity
KM388_23510	COG1523	belongs to the glycosyl hydrolase 13 family
KM388_23520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM388_23525	COG1349	DNA-binding transcription factor activity
KM388_23530	COG1187	pseudouridine synthase activity
KM388_23535	COG2244	polysaccharide biosynthetic process
KM388_23540	COG2081	HI0933 family
KM388_23545	COG2814	Major facilitator Superfamily
KM388_23555	COG3832	glyoxalase III activity
KM388_23575	COG1329	Transcriptional regulator
KM388_23585	COG4975	Glucose uptake
KM388_23600	COG0314	molybdopterin synthase activity
KM388_23605	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM388_23610	COG0303	'Molybdopterin
KM388_23620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM388_23625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM388_23645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM388_23655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM388_23695	COG2814	Major facilitator Superfamily
KM388_23700	COG0475	glutathione-regulated potassium exporter activity
KM388_23705	COG0490	domain, Protein
KM388_23710	COG0582	viral genome integration into host DNA
KM388_23720	COG1136	(ABC) transporter
KM388_23740	COG1242	4 iron, 4 sulfur cluster binding
KM388_23745	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM388_23750	COG1131	(ABC) transporter
KM388_23760	COG1794	racemase activity, acting on amino acids and derivatives
KM388_23780	COG2267	carboxylic ester hydrolase activity
KM388_23785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM388_23790	COG0671	phosphoesterase, PA-phosphatase related
KM388_23795	COG0438	transferase activity, transferring glycosyl groups
KM388_23805	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM388_23860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM388_23865	COG5002	protein histidine kinase activity
KM388_23870	COG4191	Histidine kinase
KM388_23875	COG2267	carboxylic ester hydrolase activity
KM388_23895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM388_23900	COG1116	anion transmembrane transporter activity
KM388_23905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM388_23930	COG0494	nUDIX hydrolase
KM388_23960	COG0288	reversible hydration of carbon dioxide
KM388_23965	COG1271	oxidase subunit
KM388_23970	COG1294	oxidase, subunit
KM388_23990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_24015	COG1842	Phage shock protein A
KM388_24045	COG5002	protein histidine kinase activity
KM388_24050	COG0745	RESPONSE REGULATOR receiver
KM388_24075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM388_24080	COG1597	lipid kinase activity
KM388_24115	COG0586	Pfam SNARE associated Golgi protein
KM388_24125	COG0577	efflux transmembrane transporter activity
KM388_24130	COG1136	(ABC) transporter
KM388_24140	COG0745	RESPONSE REGULATOR receiver
KM388_24145	COG2205	protein histidine kinase activity
KM388_24150	COG0577	efflux transmembrane transporter activity
KM388_24155	COG0577	efflux transmembrane transporter activity
KM388_24160	COG1136	(ABC) transporter
KM388_24180	COG2188	Transcriptional regulator
KM388_24200	COG3964	amidohydrolase
KM388_24230	COG4948	Mandelate Racemase Muconate Lactonizing
KM388_24240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM388_24245	COG0596	Alpha beta hydrolase
KM388_24250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM388_24255	COG1169	isochorismate synthase
KM388_24260	COG1575	Belongs to the MenA family. Type 1 subfamily
KM388_24265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM388_24285	COG0058	SHG alpha-glucan phosphorylase activity
KM388_24290	COG0297	glycogen (starch) synthase activity
KM388_24295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM388_24415	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM388_24450	COG1285	pathogenesis
KM388_24455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM388_24465	COG0166	Belongs to the GPI family
KM388_24470	COG2155	Conserved Protein
KM388_24475	COG1098	S1 RNA binding domain
KM388_24480	COG0436	Aminotransferase
KM388_24485	COG1522	sequence-specific DNA binding
KM388_24490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM388_24495	COG2267	carboxylic ester hydrolase activity
KM388_24505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM388_24525	COG5018	Exonuclease
KM388_24530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM388_24550	COG2050	protein possibly involved in aromatic compounds catabolism
KM388_24560	COG1268	BioY protein
KM388_24570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM388_24575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM388_24590	COG3584	3D domain protein
KM388_24605	COG1252	NADH dehydrogenase
KM388_24620	COG3708	Transcriptional regulator
KM388_24635	COG1683	Conserved Protein
KM388_24655	COG0316	Belongs to the HesB IscA family
KM388_24670	COG1252	NADH dehydrogenase
KM388_24680	COG2274	protein secretion by the type I secretion system
KM388_24685	COG0390	transport system, permease component
KM388_24690	COG2824	Alkylphosphonate utilization operon protein PhnA
KM388_24730	COG4837	Protein of unknown function (DUF1462)
KM388_24735	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM388_24745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM388_24750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM388_24760	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM388_24765	COG0647	UMP catabolic process
KM388_24775	COG2445	Protein of unknown function DUF86
KM388_24780	COG1494	fructose-1,6-bisphosphatase
KM388_24795	COG4470	Protein conserved in bacteria
KM388_24805	COG0789	Transcriptional regulator
KM388_24810	COG4377	Putative membrane peptidase family (DUF2324)
KM388_24835	COG0739	heme binding
KM388_24845	COG3377	Domain of unknown function (DUF1805)
KM388_24850	COG0737	Belongs to the 5'-nucleotidase family
KM388_24855	COG1695	Transcriptional regulator
KM388_24865	COG0719	Fe-S assembly protein
KM388_24870	COG0822	iron-sulfur transferase activity
KM388_24875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM388_24880	COG0719	Fe-S assembly protein
KM388_24885	COG0396	ATPase activity
KM388_24890	COG1464	Belongs to the NlpA lipoprotein family
KM388_24895	COG1464	Belongs to the NlpA lipoprotein family
KM388_24900	COG2011	ABC-type metal ion transport system permease component
KM388_24905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM388_24915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM388_24920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM388_24930	COG1393	Belongs to the ArsC family
KM388_24975	COG0039	L-malate dehydrogenase activity
KM388_24995	COG1309	transcriptional regulator
KM388_25000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM388_25005	COG1960	acyl-CoA dehydrogenase activity
KM388_25010	COG0183	Belongs to the thiolase family
KM388_25015	COG1024	Enoyl-CoA hydratase
KM388_25015	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM388_25025	COG1686	Belongs to the peptidase S11 family
KM388_25040	COG0011	TIGRFAM Protein of
KM388_25045	COG0840	transmembrane signaling receptor activity
KM388_25065	COG2814	Major facilitator Superfamily
KM388_25070	COG0531	amino acid
KM388_25080	COG0706	membrane insertase activity
KM388_25090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM388_25125	COG0586	Pfam SNARE associated Golgi protein
KM388_25135	COG1376	ErfK ybiS ycfS ynhG family protein
KM388_25140	COG0745	RESPONSE REGULATOR receiver
KM388_25145	COG5002	protein histidine kinase activity
KM388_25170	COG2151	metal-sulfur cluster biosynthetic enzyme
KM388_25175	COG3227	Zinc metalloprotease (Elastase)
KM388_25180	COG1741	Belongs to the pirin family
KM388_25195	COG0475	glutathione-regulated potassium exporter activity
KM388_25200	COG0490	domain, Protein
KM388_25205	COG1115	amino acid carrier protein
KM388_25210	COG0783	Belongs to the Dps family
KM388_25225	COG1611	Belongs to the LOG family
KM388_25245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_25250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_25255	COG1115	amino acid carrier protein
KM388_25260	COG1115	amino acid carrier protein
KM388_25265	COG2910	NAD(P)H-binding
KM388_25280	COG0656	L-ascorbic acid biosynthetic process
KM388_25285	COG2814	Major facilitator Superfamily
KM388_25290	COG1733	regulation of RNA biosynthetic process
KM388_25300	COG1252	NADH dehydrogenase
KM388_25305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM388_25310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM388_25320	COG0840	transmembrane signaling receptor activity
KM388_25320	COG3290	protein histidine kinase activity
KM388_25330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM388_25335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM388_25350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM388_25405	COG0557	exoribonuclease II activity
KM388_25410	COG1647	Serine aminopeptidase, S33
KM388_25415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM388_25420	COG1346	cytolysis
KM388_25520	COG4695	Portal protein
KM388_25540	COG4974	Belongs to the 'phage' integrase family
KM388_25555	COG0149	triose-phosphate isomerase activity
KM388_25565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM388_25580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM388_25605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM388_25620	COG2323	membrane
KM388_25625	COG0740	serine-type endopeptidase activity
KM388_25630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM388_25640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM388_25650	COG1051	belongs to the nudix hydrolase family
KM388_25660	COG0492	ferredoxin-NADP+ reductase activity
KM388_25665	COG0457	Tetratricopeptide repeat
KM388_25670	COG0110	maltose O-acetyltransferase activity
KM388_25690	COG1950	PFAM Membrane protein of
KM388_25700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM388_25705	COG0556	nucleotide-excision repair
KM388_25725	COG0789	Transcriptional regulator
KM388_25750	COG2855	membrane
KM388_25755	COG0583	DNA-binding transcription factor activity
KM388_25765	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM388_25770	COG0488	(ABC) transporter
KM388_25780	COG1132	(ABC) transporter
KM388_25785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM388_25790	COG0793	Belongs to the peptidase S41A family
KM388_25790	COG3409	Peptidoglycan-binding domain 1 protein
KM388_25795	COG2177	Part of the ABC transporter FtsEX involved in
KM388_25800	COG2884	Cell division ATP-binding protein ftsE
KM388_25815	COG0653	protein targeting
KM388_25820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM388_25825	COG1278	Cold shock
KM388_25830	COG1040	competence protein
KM388_25840	COG0791	NLP P60 protein
KM388_25840	COG1388	LysM domain
KM388_25845	COG1733	regulation of RNA biosynthetic process
KM388_25850	COG1307	EDD domain protein, DegV family
KM388_25855	COG1739	Uncharacterized protein family UPF0029
KM388_25860	COG1316	TRANSCRIPTIONal
KM388_25865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM388_25870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM388_25875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM388_25885	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM388_25885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM388_25900	COG3394	polysaccharide catabolic process
KM388_25905	COG1486	melibiose metabolic process
KM388_25910	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM388_25915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM388_25925	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM388_25930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM388_25935	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM388_25945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM388_25950	COG1301	dicarboxylic acid transport
KM388_25960	COG0346	lactoylglutathione lyase activity
KM388_25965	COG1511	domain protein
KM388_25970	COG0583	DNA-binding transcription factor activity
KM388_25975	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM388_25990	COG1271	oxidase subunit
KM388_25995	COG1294	oxidase, subunit
KM388_26000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM388_26010	COG1620	l-lactate permease
KM388_26020	COG2389	metal-binding protein
KM388_26030	COG1368	sulfuric ester hydrolase activity
KM388_26045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM388_26055	COG1215	transferase activity, transferring glycosyl groups
KM388_26060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM388_26065	COG3584	3D domain protein
KM388_26065	COG1388	LysM domain
KM388_26090	COG4715	Zinc finger, swim domain protein
KM388_26095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM388_26135	COG0577	efflux transmembrane transporter activity
KM388_26140	COG1136	(ABC) transporter
KM388_26175	COG5002	protein histidine kinase activity
KM388_26180	COG0745	RESPONSE REGULATOR receiver
KM388_26185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM388_26200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM388_26205	COG1134	teichoic acid transport
KM388_26210	COG1682	transport, permease protein
KM388_26215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM388_26260	COG1609	Transcriptional regulator
KM388_26275	COG0739	heme binding
KM388_26295	COG2385	sporulation resulting in formation of a cellular spore
KM388_26310	COG4836	Membrane
KM388_26315	COG1007	ATP synthesis coupled electron transport
KM388_26320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM388_26325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM388_26335	COG0839	Belongs to the complex I subunit 6 family
KM388_26350	COG0649	NAD binding
KM388_26355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM388_26370	COG5001	Diguanylate cyclase
KM388_26370	COG3300	MHYT domain
KM388_26420	COG0356	it plays a direct role in the translocation of protons across the membrane
KM388_26455	COG0698	ribose 5-phosphate isomerase
KM388_26465	COG2190	(PTS) system
KM388_26470	COG2259	Doxx family
KM388_26475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM388_26490	COG0009	L-threonylcarbamoyladenylate synthase
KM388_26505	COG2890	protein-(glutamine-N5) methyltransferase activity
KM388_26525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM388_26530	COG1494	fructose-1,6-bisphosphatase
KM388_26550	COG4821	SIS domain
KM388_26560	COG3343	RNA polymerase activity
KM388_26570	COG1960	acyl-CoA dehydrogenase activity
KM388_26575	COG1960	acyl-CoA dehydrogenase activity
KM388_26580	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM388_26585	COG0183	Belongs to the thiolase family
KM388_26590	COG2181	nitrate reductase activity
KM388_26590	COG0247	lactate metabolic process
KM388_26595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM388_26605	COG3300	MHYT domain
KM388_26605	COG5001	Diguanylate cyclase
KM388_26625	COG2197	response regulator
KM388_26630	COG4585	Histidine kinase
KM388_26635	COG0842	Transport permease protein
KM388_26640	COG1131	(ABC) transporter
KM388_26645	COG0024	Methionine aminopeptidase
KM388_26655	COG2234	aminopeptidase activity
KM388_26675	COG1595	DNA-templated transcription, initiation
KM388_26680	COG0018	arginyl-trna synthetase
KM388_26685	COG4506	Protein conserved in bacteria
KM388_26690	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM388_26705	COG0010	Belongs to the arginase family
KM388_26715	COG2814	Major facilitator Superfamily
KM388_26720	COG0789	Transcriptional regulator
KM388_26725	COG0584	glycerophosphoryl diester phosphodiesterase
KM388_26730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM388_26740	COG1994	Peptidase M50
KM388_26750	COG1078	dGTPase activity
KM388_26755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM388_26760	COG1120	ATPase activity
KM388_26765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM388_26790	COG0095	Lipoate-protein ligase
KM388_26795	COG0280	phosphate acetyltransferase
KM388_26810	COG3773	Cell wall hydrolase
KM388_26820	COG2363	Small membrane protein
KM388_26830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM388_26835	COG2233	PERMEase
KM388_26840	COG0561	phosphatase activity
KM388_26845	COG2814	Major facilitator Superfamily
KM388_26855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM388_26860	COG1131	(ABC) transporter
KM388_26865	COG2755	lipolytic protein G-D-S-L family
KM388_26870	COG1609	Transcriptional regulator
KM388_26880	COG0460	homoserine dehydrogenase
KM388_26890	COG2873	o-acetylhomoserine
KM388_26900	COG1011	Hydrolase
KM388_26905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM388_26915	COG2197	response regulator
KM388_26925	COG0351	phosphomethylpyrimidine kinase
KM388_26930	COG3706	GGDEF domain
KM388_26935	COG2879	small protein
KM388_26940	COG1966	Carbon starvation protein
KM388_26945	COG3279	Response regulator of the LytR AlgR family
KM388_26950	COG0477	Major facilitator Superfamily
KM388_26985	COG1607	acyl-coa hydrolase
KM388_27000	COG0488	(ABC) transporter
KM388_27020	COG0463	Glycosyl transferase, family 2
KM388_27025	COG1309	transcriptional regulator
KM388_27030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM388_27035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM388_27035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM388_27040	COG0628	permease
KM388_27055	COG3279	Response regulator of the LytR AlgR family
KM388_27060	COG3275	phosphorelay sensor kinase activity
KM388_27065	COG2814	Major facilitator Superfamily
KM388_27070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM388_27075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM388_27080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM388_27100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM388_27105	COG1272	protein, Hemolysin III
KM388_27130	COG1164	Oligoendopeptidase f
KM388_27150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM388_27155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM388_27160	COG4853	Protein conserved in bacteria
KM388_27165	COG4863	YycH protein
KM388_27170	COG5002	protein histidine kinase activity
KM388_27175	COG0745	RESPONSE REGULATOR receiver
KM388_27205	COG0305	Participates in initiation and elongation during chromosome replication
KM388_27215	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM388_27220	COG4241	membrane
KM388_27230	COG0629	single-stranded DNA binding
KM388_27240	COG0012	GTP binding
KM388_27245	COG4481	Protein conserved in bacteria
KM388_27250	COG0668	transmembrane transport
KM388_27260	COG1475	DNA binding
KM388_27265	COG1192	Involved in chromosome partitioning
KM388_27290	COG1847	R3H domain protein
KM388_27295	COG0706	membrane insertase activity
KM388_27305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM388_27355	COG3344	reverse transcriptase
KM388_27435	COG3344	reverse transcriptase
KM388_27765	COG2311	Membrane
KM388_27785	COG4196	transglutaminase domain protein
KM388_27790	COG0671	phosphoesterase, PA-phosphatase related
KM388_27805	COG1215	transferase activity, transferring glycosyl groups
KM388_27810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM388_27815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM388_27970	COG2002	toxin-antitoxin pair type II binding
KM388_27980	COG4974	Belongs to the 'phage' integrase family
KM388_28035	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM388_28040	COG4974	Belongs to the 'phage' integrase family
KM388_28065	COG0457	Tetratricopeptide repeat
KM388_28335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM388_28340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM388_28395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM388_28405	COG4166	transmembrane transport
KM388_28445	COG1280	lysine exporter protein (LysE YggA)
KM388_28470	COG0681	Belongs to the peptidase S26 family
KM388_28545	COG1309	transcriptional regulator
KM388_28550	COG1683	Conserved Protein
KM388_28590	COG1192	Involved in chromosome partitioning