locus-tag	class	description
BF31_1	COG0745	RESPONSE REGULATOR receiver
BF31_100	COG0420	3'-5' exonuclease activity
BF31_1016	COG0726	polysaccharide deacetylase
BF31_1017	COG2194	sulfuric ester hydrolase activity
BF31_1019	COG0489	protein tyrosine kinase activity
BF31_1020	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF31_1024	COG0101	tRNA pseudouridine synthase activity
BF31_1025	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF31_1026	COG1122	ATPase activity
BF31_1032	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF31_1034	COG0024	Methionine aminopeptidase
BF31_1036	COG0201	protein transport
BF31_1041	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF31_106	COG0393	Putative heavy-metal-binding
BF31_1062	COG1358	cellular component organization or biogenesis
BF31_1063	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF31_1065	COG2813	Specifically methylates the guanine in position
BF31_1070	COG0250	Participates in transcription elongation, termination and antitermination
BF31_1071	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF31_1073	COG3688	RNA-binding protein containing a PIN domain
BF31_1078	COG1045	serine acetyltransferase
BF31_1082	COG4956	integral membrane protein (PIN domain superfamily)
BF31_1084	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF31_1085	COG0542	response to heat
BF31_1087	COG3880	PFAM UvrB UvrC protein
BF31_1094	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF31_1095	COG1396	sequence-specific DNA binding
BF31_1096	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF31_1097	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF31_1098	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF31_1099	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF31_1100	COG0512	Glutamine amidotransferase of anthranilate synthase
BF31_1101	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF31_1102	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF31_1105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF31_1107	COG0037	tRNA processing
BF31_1108	COG2208	phosphoserine phosphatase activity
BF31_111	COG2198	Histidine kinase
BF31_111	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF31_111	COG0784	Response regulator, receiver
BF31_111	COG2205	protein histidine kinase activity
BF31_1111	COG1098	S1 RNA binding domain
BF31_1115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF31_1116	COG3956	TIGRFAM MazG family protein
BF31_1117	COG2244	polysaccharide biosynthetic process
BF31_1118	COG2002	toxin-antitoxin pair type II binding
BF31_1119	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF31_112	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF31_1121	COG0193	aminoacyl-tRNA hydrolase activity
BF31_1122	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF31_1125	COG0251	oxidation-reduction process
BF31_1126	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF31_1129	COG4466	Protein conserved in bacteria
BF31_113	COG2208	phosphoserine phosphatase activity
BF31_1132	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF31_1133	COG0084	hydrolase, TatD family'
BF31_1134	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_1134	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_1135	COG2002	toxin-antitoxin pair type II binding
BF31_1136	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF31_1138	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF31_1140	COG1774	PSP1 C-terminal conserved region
BF31_1141	COG0470	DNA polymerase III
BF31_1143	COG1982	Orn Lys Arg decarboxylase major
BF31_115	COG1191	sigma factor activity
BF31_1155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF31_1156	COG0590	tRNA wobble adenosine to inosine editing
BF31_1157	COG1335	isochorismatase
BF31_1158	COG1428	Deoxynucleoside kinase
BF31_1159	COG1428	Deoxynucleoside kinase
BF31_1165	COG1686	Belongs to the peptidase S11 family
BF31_1166	COG0517	IMP dehydrogenase activity
BF31_1166	COG0516	GMP reductase activity
BF31_1175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF31_1176	COG0187	DNA topoisomerase II activity
BF31_1178	COG2501	S4 domain
BF31_1179	COG0592	DNA-directed DNA polymerase activity
BF31_1183	COG0706	membrane insertase activity
BF31_1184	COG1847	R3H domain protein
BF31_1185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF31_1189	COG1192	Involved in chromosome partitioning
BF31_1190	COG1475	DNA binding
BF31_1192	COG0668	transmembrane transport
BF31_1193	COG4481	Protein conserved in bacteria
BF31_1194	COG0012	GTP binding
BF31_1196	COG0629	single-stranded DNA binding
BF31_1198	COG4241	membrane
BF31_1199	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF31_120	COG3237	CsbD-like
BF31_1201	COG0305	Participates in initiation and elongation during chromosome replication
BF31_1207	COG0745	RESPONSE REGULATOR receiver
BF31_1208	COG5002	protein histidine kinase activity
BF31_1209	COG4863	YycH protein
BF31_1210	COG4853	Protein conserved in bacteria
BF31_1211	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF31_1212	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF31_1216	COG1164	Oligoendopeptidase f
BF31_1217	COG0516	GMP reductase activity
BF31_1221	COG1272	protein, Hemolysin III
BF31_1222	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF31_1226	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF31_1227	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF31_1228	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF31_1229	COG2814	Major facilitator Superfamily
BF31_1230	COG3275	phosphorelay sensor kinase activity
BF31_1231	COG3279	Response regulator of the LytR AlgR family
BF31_1234	COG0628	permease
BF31_1235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF31_1235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF31_1236	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF31_1237	COG1309	transcriptional regulator
BF31_1238	COG0463	Glycosyl transferase, family 2
BF31_1243	COG0488	(ABC) transporter
BF31_1246	COG1607	acyl-coa hydrolase
BF31_1248	COG0840	transmembrane signaling receptor activity
BF31_1253	COG0477	Major facilitator Superfamily
BF31_1254	COG3279	Response regulator of the LytR AlgR family
BF31_1255	COG1966	Carbon starvation protein
BF31_1256	COG2879	small protein
BF31_1257	COG3706	GGDEF domain
BF31_1258	COG0351	phosphomethylpyrimidine kinase
BF31_1259	COG4585	Histidine kinase
BF31_1259	COG2203	Gaf domain
BF31_1260	COG4585	Histidine kinase
BF31_1260	COG2203	Gaf domain
BF31_1261	COG2197	response regulator
BF31_1263	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF31_1264	COG1011	Hydrolase
BF31_1268	COG0460	homoserine dehydrogenase
BF31_1270	COG1609	Transcriptional regulator
BF31_1271	COG2755	lipolytic protein G-D-S-L family
BF31_1272	COG1131	(ABC) transporter
BF31_1273	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF31_1275	COG2814	Major facilitator Superfamily
BF31_1276	COG0561	phosphatase activity
BF31_1277	COG2233	PERMEase
BF31_1278	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF31_1280	COG2363	Small membrane protein
BF31_1282	COG3773	Cell wall hydrolase
BF31_1285	COG0280	phosphate acetyltransferase
BF31_1286	COG0095	Lipoate-protein ligase
BF31_1290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_1291	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_1292	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_1293	COG1120	ATPase activity
BF31_1294	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_1295	COG1078	dGTPase activity
BF31_1297	COG1994	Peptidase M50
BF31_1299	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF31_130	COG3437	response regulator, receiver
BF31_130	COG2770	Histidine kinase
BF31_1300	COG0584	glycerophosphoryl diester phosphodiesterase
BF31_1301	COG0789	Transcriptional regulator
BF31_1302	COG2814	Major facilitator Superfamily
BF31_1303	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF31_1304	COG0010	Belongs to the arginase family
BF31_1307	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF31_1308	COG4506	Protein conserved in bacteria
BF31_1309	COG0018	arginyl-trna synthetase
BF31_1310	COG1595	DNA-templated transcription, initiation
BF31_1314	COG2234	aminopeptidase activity
BF31_1318	COG0024	Methionine aminopeptidase
BF31_1319	COG1131	(ABC) transporter
BF31_1320	COG0842	Transport permease protein
BF31_1321	COG4585	Histidine kinase
BF31_1322	COG2197	response regulator
BF31_1326	COG5001	Diguanylate cyclase
BF31_1326	COG3300	MHYT domain
BF31_1328	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF31_1329	COG0247	lactate metabolic process
BF31_1329	COG2181	nitrate reductase activity
BF31_1330	COG0183	Belongs to the thiolase family
BF31_1331	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF31_1332	COG1960	acyl-CoA dehydrogenase activity
BF31_1333	COG1960	acyl-CoA dehydrogenase activity
BF31_1335	COG3343	RNA polymerase activity
BF31_1337	COG4821	SIS domain
BF31_1340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF31_1341	COG1494	fructose-1,6-bisphosphatase
BF31_1342	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF31_1345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF31_1346	COG2890	protein-(glutamine-N5) methyltransferase activity
BF31_1349	COG0009	L-threonylcarbamoyladenylate synthase
BF31_1352	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF31_1353	COG2259	Doxx family
BF31_1354	COG2190	(PTS) system
BF31_1356	COG0698	ribose 5-phosphate isomerase
BF31_136	COG1959	2 iron, 2 sulfur cluster binding
BF31_1362	COG0356	it plays a direct role in the translocation of protons across the membrane
BF31_137	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF31_1372	COG3300	MHYT domain
BF31_1372	COG5001	Diguanylate cyclase
BF31_1373	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF31_1375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF31_1376	COG0649	NAD binding
BF31_1379	COG0839	Belongs to the complex I subunit 6 family
BF31_138	COG2376	Dihydroxyacetone kinase
BF31_1381	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF31_1382	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF31_1383	COG1007	ATP synthesis coupled electron transport
BF31_1384	COG4836	Membrane
BF31_1386	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF31_1387	COG2385	sporulation resulting in formation of a cellular spore
BF31_1388	COG4555	ABC transporter
BF31_1389	COG3279	Response regulator of the LytR AlgR family
BF31_1392	COG0739	heme binding
BF31_1394	COG1609	Transcriptional regulator
BF31_140	COG2376	Dihydroxyacetone kinase
BF31_1402	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF31_1403	COG1682	transport, permease protein
BF31_1404	COG1134	teichoic acid transport
BF31_1405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF31_1406	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF31_1407	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF31_1409	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF31_1409	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF31_1412	COG3394	polysaccharide catabolic process
BF31_1413	COG1486	melibiose metabolic process
BF31_1414	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF31_1415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF31_1417	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF31_1418	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF31_1419	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF31_1421	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF31_1422	COG1301	dicarboxylic acid transport
BF31_1424	COG0346	lactoylglutathione lyase activity
BF31_1425	COG1511	domain protein
BF31_1426	COG0583	DNA-binding transcription factor activity
BF31_1427	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF31_1430	COG1271	oxidase subunit
BF31_1431	COG1294	oxidase, subunit
BF31_1432	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF31_1434	COG1620	l-lactate permease
BF31_1436	COG2389	metal-binding protein
BF31_1438	COG1368	sulfuric ester hydrolase activity
BF31_144	COG1183	phosphatidylcholine synthase activity
BF31_1441	COG0791	NLP P60 protein
BF31_1441	COG1388	LysM domain
BF31_1442	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_1444	COG1215	transferase activity, transferring glycosyl groups
BF31_1446	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF31_1447	COG3584	3D domain protein
BF31_1447	COG1388	LysM domain
BF31_1452	COG4715	Zinc finger, swim domain protein
BF31_1453	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF31_1459	COG1191	sigma factor activity
BF31_1461	COG0577	efflux transmembrane transporter activity
BF31_1462	COG1136	(ABC) transporter
BF31_1469	COG5002	protein histidine kinase activity
BF31_1470	COG0745	RESPONSE REGULATOR receiver
BF31_1471	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF31_1474	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF31_1475	COG1316	TRANSCRIPTIONal
BF31_1476	COG1739	Uncharacterized protein family UPF0029
BF31_1477	COG1307	EDD domain protein, DegV family
BF31_1478	COG1733	regulation of RNA biosynthetic process
BF31_1479	COG0791	NLP P60 protein
BF31_1479	COG1388	LysM domain
BF31_1480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF31_1481	COG1040	competence protein
BF31_1482	COG1278	Cold shock
BF31_1483	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF31_1484	COG0653	protein targeting
BF31_1485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF31_1487	COG2884	Cell division ATP-binding protein ftsE
BF31_1488	COG2177	Part of the ABC transporter FtsEX involved in
BF31_1489	COG0793	Belongs to the peptidase S41A family
BF31_1489	COG3409	Peptidoglycan-binding domain 1 protein
BF31_149	COG3320	Male sterility
BF31_149	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF31_1490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF31_1491	COG1132	(ABC) transporter
BF31_1494	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF31_1496	COG0583	DNA-binding transcription factor activity
BF31_1497	COG2855	membrane
BF31_1501	COG0789	Transcriptional regulator
BF31_1505	COG0556	nucleotide-excision repair
BF31_1506	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF31_1508	COG1950	PFAM Membrane protein of
BF31_1512	COG0110	maltose O-acetyltransferase activity
BF31_1513	COG0457	Tetratricopeptide repeat
BF31_1514	COG0492	ferredoxin-NADP+ reductase activity
BF31_1516	COG1051	belongs to the nudix hydrolase family
BF31_1518	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF31_1520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF31_1521	COG0740	serine-type endopeptidase activity
BF31_1522	COG2323	membrane
BF31_1525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_1530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF31_1533	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF31_1535	COG0149	triose-phosphate isomerase activity
BF31_1536	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF31_1538	COG4974	Belongs to the 'phage' integrase family
BF31_1543	COG4695	Portal protein
BF31_1562	COG1346	cytolysis
BF31_1563	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF31_1564	COG1647	Serine aminopeptidase, S33
BF31_1565	COG0557	exoribonuclease II activity
BF31_1574	COG3223	Belongs to the PsiE family
BF31_1575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_1578	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF31_1579	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF31_1581	COG3290	protein histidine kinase activity
BF31_1581	COG0840	transmembrane signaling receptor activity
BF31_1583	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF31_1584	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF31_1585	COG1252	NADH dehydrogenase
BF31_1587	COG1733	regulation of RNA biosynthetic process
BF31_1588	COG2814	Major facilitator Superfamily
BF31_1589	COG0656	L-ascorbic acid biosynthetic process
BF31_159	COG0477	Major facilitator Superfamily
BF31_1594	COG2910	NAD(P)H-binding
BF31_1595	COG1115	amino acid carrier protein
BF31_1596	COG1115	amino acid carrier protein
BF31_1597	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_1598	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_16	COG3209	COG3209 Rhs family protein
BF31_1600	COG2311	Membrane
BF31_1603	COG1611	Belongs to the LOG family
BF31_1606	COG0783	Belongs to the Dps family
BF31_1607	COG1115	amino acid carrier protein
BF31_1608	COG0490	domain, Protein
BF31_1609	COG0475	glutathione-regulated potassium exporter activity
BF31_1612	COG1741	Belongs to the pirin family
BF31_1613	COG3227	Zinc metalloprotease (Elastase)
BF31_1614	COG2151	metal-sulfur cluster biosynthetic enzyme
BF31_1617	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_1619	COG5002	protein histidine kinase activity
BF31_1620	COG0745	RESPONSE REGULATOR receiver
BF31_1621	COG1376	ErfK ybiS ycfS ynhG family protein
BF31_1623	COG0586	Pfam SNARE associated Golgi protein
BF31_1630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_1632	COG0706	membrane insertase activity
BF31_1634	COG0531	amino acid
BF31_1635	COG2814	Major facilitator Superfamily
BF31_1639	COG0840	transmembrane signaling receptor activity
BF31_1640	COG0011	TIGRFAM Protein of
BF31_1643	COG1686	Belongs to the peptidase S11 family
BF31_1645	COG1024	Enoyl-CoA hydratase
BF31_1645	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF31_1646	COG0183	Belongs to the thiolase family
BF31_1647	COG1960	acyl-CoA dehydrogenase activity
BF31_1648	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_1649	COG1309	transcriptional regulator
BF31_1654	COG0039	L-malate dehydrogenase activity
BF31_1663	COG1393	Belongs to the ArsC family
BF31_1665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF31_1666	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF31_1668	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF31_1669	COG2011	ABC-type metal ion transport system permease component
BF31_167	COG0305	Participates in initiation and elongation during chromosome replication
BF31_1670	COG1464	Belongs to the NlpA lipoprotein family
BF31_1671	COG1464	Belongs to the NlpA lipoprotein family
BF31_1672	COG0396	ATPase activity
BF31_1673	COG0719	Fe-S assembly protein
BF31_1674	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF31_1675	COG0822	iron-sulfur transferase activity
BF31_1676	COG0719	Fe-S assembly protein
BF31_1678	COG1695	Transcriptional regulator
BF31_1679	COG0737	Belongs to the 5'-nucleotidase family
BF31_1680	COG3377	Domain of unknown function (DUF1805)
BF31_1682	COG0739	heme binding
BF31_1687	COG4377	Putative membrane peptidase family (DUF2324)
BF31_1688	COG0789	Transcriptional regulator
BF31_1690	COG4470	Protein conserved in bacteria
BF31_1693	COG1494	fructose-1,6-bisphosphatase
BF31_1694	COG2445	Protein of unknown function DUF86
BF31_1696	COG0647	UMP catabolic process
BF31_1697	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF31_1699	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF31_170	COG4978	Transcriptional regulator
BF31_170	COG0789	Transcriptional regulator
BF31_1700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF31_1702	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF31_1703	COG4837	Protein of unknown function (DUF1462)
BF31_1711	COG2824	Alkylphosphonate utilization operon protein PhnA
BF31_1712	COG0390	transport system, permease component
BF31_1714	COG1252	NADH dehydrogenase
BF31_1717	COG0316	Belongs to the HesB IscA family
BF31_1720	COG1683	Conserved Protein
BF31_1723	COG3708	Transcriptional regulator
BF31_1726	COG1252	NADH dehydrogenase
BF31_1729	COG3584	3D domain protein
BF31_1732	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF31_1733	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF31_1735	COG1268	BioY protein
BF31_1737	COG2050	protein possibly involved in aromatic compounds catabolism
BF31_1738	COG0423	glycine-tRNA ligase activity
BF31_1741	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF31_1742	COG5018	Exonuclease
BF31_1746	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF31_1748	COG2267	carboxylic ester hydrolase activity
BF31_1749	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF31_175	COG3181	Tripartite tricarboxylate transporter family receptor
BF31_1750	COG1522	sequence-specific DNA binding
BF31_1751	COG0436	Aminotransferase
BF31_1752	COG1098	S1 RNA binding domain
BF31_1753	COG2155	Conserved Protein
BF31_1754	COG0166	Belongs to the GPI family
BF31_1755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF31_1757	COG1285	pathogenesis
BF31_176	COG4565	transcriptional regulatory protein
BF31_1765	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF31_177	COG3290	protein histidine kinase activity
BF31_178	COG0477	Major facilitator Superfamily
BF31_1784	COG0039	L-malate dehydrogenase activity
BF31_1786	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF31_1787	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF31_1788	COG0297	glycogen (starch) synthase activity
BF31_1789	COG0058	SHG alpha-glucan phosphorylase activity
BF31_1793	COG1278	Cold shock
BF31_1794	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF31_1795	COG1575	Belongs to the MenA family. Type 1 subfamily
BF31_1796	COG1169	isochorismate synthase
BF31_1797	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF31_1798	COG0596	Alpha beta hydrolase
BF31_1799	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF31_1801	COG4948	Mandelate Racemase Muconate Lactonizing
BF31_1807	COG3964	amidohydrolase
BF31_1814	COG0577	efflux transmembrane transporter activity
BF31_1815	COG0577	efflux transmembrane transporter activity
BF31_1816	COG1136	(ABC) transporter
BF31_1817	COG0577	efflux transmembrane transporter activity
BF31_1818	COG0577	efflux transmembrane transporter activity
BF31_1819	COG0577	efflux transmembrane transporter activity
BF31_1820	COG2205	protein histidine kinase activity
BF31_1821	COG0745	RESPONSE REGULATOR receiver
BF31_1822	COG3708	Transcriptional regulator
BF31_1822	COG2207	Transcriptional regulator
BF31_1823	COG1136	(ABC) transporter
BF31_1824	COG0577	efflux transmembrane transporter activity
BF31_1826	COG0586	Pfam SNARE associated Golgi protein
BF31_1833	COG1597	lipid kinase activity
BF31_1839	COG0745	RESPONSE REGULATOR receiver
BF31_184	COG4608	Belongs to the ABC transporter superfamily
BF31_1840	COG5002	protein histidine kinase activity
BF31_1847	COG1842	Phage shock protein A
BF31_185	COG0444	Belongs to the ABC transporter superfamily
BF31_1852	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_1856	COG1294	oxidase, subunit
BF31_1857	COG1271	oxidase subunit
BF31_1859	COG0288	reversible hydration of carbon dioxide
BF31_186	COG0444	Belongs to the ABC transporter superfamily
BF31_1864	COG0494	nUDIX hydrolase
BF31_1866	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF31_187	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF31_1870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF31_1871	COG1116	anion transmembrane transporter activity
BF31_1872	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF31_1876	COG1368	sulfuric ester hydrolase activity
BF31_1877	COG2267	carboxylic ester hydrolase activity
BF31_1878	COG4191	Histidine kinase
BF31_1879	COG5002	protein histidine kinase activity
BF31_188	COG0601	transmembrane transport
BF31_1880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF31_1890	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF31_1892	COG0438	transferase activity, transferring glycosyl groups
BF31_1893	COG0671	phosphoesterase, PA-phosphatase related
BF31_1894	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF31_1895	COG2267	carboxylic ester hydrolase activity
BF31_1899	COG1794	racemase activity, acting on amino acids and derivatives
BF31_1901	COG1131	(ABC) transporter
BF31_1902	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF31_1903	COG1242	4 iron, 4 sulfur cluster binding
BF31_1907	COG1136	(ABC) transporter
BF31_1909	COG0582	viral genome integration into host DNA
BF31_1910	COG0490	domain, Protein
BF31_1911	COG0475	glutathione-regulated potassium exporter activity
BF31_1912	COG2814	Major facilitator Superfamily
BF31_1920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF31_1922	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_1926	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF31_1927	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF31_1929	COG0303	'Molybdopterin
BF31_1930	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF31_1931	COG0314	molybdopterin synthase activity
BF31_1934	COG4975	Glucose uptake
BF31_1936	COG1329	Transcriptional regulator
BF31_1940	COG3832	glyoxalase III activity
BF31_1942	COG2814	Major facilitator Superfamily
BF31_1943	COG2081	HI0933 family
BF31_1944	COG2244	polysaccharide biosynthetic process
BF31_1945	COG1187	pseudouridine synthase activity
BF31_1946	COG1349	DNA-binding transcription factor activity
BF31_1947	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF31_1948	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF31_195	COG3938	Belongs to the proline racemase family
BF31_1950	COG1523	belongs to the glycosyl hydrolase 13 family
BF31_1951	COG0510	thiamine kinase activity
BF31_1954	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_1956	COG1363	Peptidase, m42
BF31_1957	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF31_1958	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF31_1959	COG4848	Belongs to the UPF0354 family
BF31_1960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_1962	COG1674	ftsk spoiiie
BF31_1965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_1969	COG2309	aminopeptidase activity
BF31_1971	COG3118	belongs to the thioredoxin family
BF31_1972	COG4851	CamS sex pheromone cAM373 precursor
BF31_1973	COG1609	Transcriptional regulator
BF31_1980	COG0666	response to abiotic stimulus
BF31_1982	COG0745	RESPONSE REGULATOR receiver
BF31_1984	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF31_1985	COG0517	IMP dehydrogenase activity
BF31_1986	COG0454	-acetyltransferase
BF31_1987	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF31_1989	COG1595	DNA-templated transcription, initiation
BF31_199	COG1363	Peptidase, m42
BF31_1991	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF31_1995	COG0626	cystathionine gamma-synthase activity
BF31_1996	COG1956	GAF domain-containing protein
BF31_1997	COG1309	transcriptional regulator
BF31_1998	COG1309	transcriptional regulator
BF31_1999	COG0697	spore germination
BF31_2	COG2205	protein histidine kinase activity
BF31_2000	COG0583	DNA-binding transcription factor activity
BF31_2002	COG1104	cysteine desulfurase activity
BF31_2005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF31_2007	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF31_2008	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF31_2010	COG3874	Sporulation protein YtfJ
BF31_2011	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF31_2012	COG0827	DNA restriction-modification system
BF31_2013	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF31_2017	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_202	COG1024	Enoyl-CoA hydratase
BF31_2026	COG0589	response to stress
BF31_2027	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_2030	COG1476	TRANSCRIPTIONal
BF31_2032	COG0662	Cupin 2, conserved barrel domain protein
BF31_2033	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_2040	COG0006	proline dipeptidase activity
BF31_2043	COG4109	DRTGG domain
BF31_2047	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF31_205	COG1696	Membrane protein involved in D-alanine export
BF31_2050	COG0587	DNA-directed DNA polymerase activity
BF31_2051	COG0281	malic enzyme
BF31_2052	COG1725	Transcriptional regulator
BF31_2057	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF31_2058	COG0628	permease
BF31_2060	COG0372	Belongs to the citrate synthase family
BF31_2061	COG0538	isocitrate dehydrogenase activity
BF31_2065	COG0745	RESPONSE REGULATOR receiver
BF31_2066	COG5002	protein histidine kinase activity
BF31_2067	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF31_2067	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF31_2068	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF31_2069	COG1971	Probably functions as a manganese efflux pump
BF31_2070	COG0237	dephospho-CoA kinase activity
BF31_2071	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF31_2072	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF31_2074	COG3611	Membrane attachment protein
BF31_2075	COG1484	DNA-dependent DNA replication
BF31_2077	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF31_2078	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF31_208	COG4196	transglutaminase domain protein
BF31_2082	COG1363	Peptidase, m42
BF31_2083	COG1309	transcriptional regulator
BF31_2084	COG1566	PFAM secretion protein HlyD family protein
BF31_2085	COG2814	Major facilitator Superfamily
BF31_209	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF31_2090	COG1418	mRNA catabolic process
BF31_2092	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF31_2094	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_2094	COG0072	phenylalanine-tRNA ligase activity
BF31_2095	COG0017	Asparaginyl-tRNA synthetase
BF31_2101	COG1286	toxin biosynthetic process
BF31_2102	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF31_2102	COG1796	DNA polymerase
BF31_2105	COG1187	pseudouridine synthase activity
BF31_2106	COG1114	Component of the transport system for branched-chain amino acids
BF31_2107	COG5386	Cell surface protein
BF31_2109	COG5386	Cell surface protein
BF31_211	COG2244	polysaccharide biosynthetic process
BF31_2112	COG1120	ATPase activity
BF31_2113	COG4509	Sortase family
BF31_2116	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF31_2117	COG4895	conserved protein (DUF2196)
BF31_2119	COG0745	RESPONSE REGULATOR receiver
BF31_212	COG0653	protein targeting
BF31_2120	COG2205	protein histidine kinase activity
BF31_2121	COG1131	(ABC) transporter
BF31_2127	COG2318	DinB family
BF31_2131	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_2132	COG1309	transcriptional regulator
BF31_2133	COG1024	Enoyl-CoA hydratase
BF31_2134	COG2086	electron transfer activity
BF31_2135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF31_2136	COG3118	belongs to the thioredoxin family
BF31_2138	COG1719	4-vinyl reductase, 4VR
BF31_2139	COG2009	succinate dehydrogenase
BF31_2140	COG1053	succinate dehydrogenase
BF31_2141	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF31_2142	COG0824	Thioesterase
BF31_2143	COG1876	peptidase activity
BF31_2144	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF31_2145	COG1360	Flagellar Motor Protein
BF31_2146	COG1360	Flagellar Motor Protein
BF31_2147	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF31_2148	COG4152	abc transporter atp-binding protein
BF31_2149	COG1668	transmembrane transport
BF31_2150	COG1959	2 iron, 2 sulfur cluster binding
BF31_2152	COG0697	spore germination
BF31_2153	COG1396	sequence-specific DNA binding
BF31_2154	COG1983	PspC domain protein
BF31_2157	COG3279	Response regulator of the LytR AlgR family
BF31_2158	COG3275	phosphorelay sensor kinase activity
BF31_2159	COG4608	Belongs to the ABC transporter superfamily
BF31_216	COG0659	secondary active sulfate transmembrane transporter activity
BF31_2160	COG0444	Belongs to the ABC transporter superfamily
BF31_2164	COG0402	S-adenosylhomocysteine deaminase activity
BF31_2165	COG0402	S-adenosylhomocysteine deaminase activity
BF31_2167	COG2233	PERMEase
BF31_2168	COG2197	response regulator
BF31_2171	COG1309	transcriptional regulator
BF31_2175	COG5401	PFAM Sporulation and spore germination
BF31_2177	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF31_2178	COG0622	Phosphoesterase
BF31_2188	COG1067	ATP-dependent peptidase activity
BF31_2188	COG0470	DNA polymerase III
BF31_219	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF31_2191	COG1764	response to oxidative stress
BF31_2192	COG1846	Transcriptional regulator
BF31_2194	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF31_2196	COG1587	Uroporphyrinogen-III synthase
BF31_2197	COG0113	porphobilinogen synthase activity
BF31_2199	COG1388	LysM domain
BF31_22	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_2201	COG0525	valine-tRNA ligase activity
BF31_2202	COG0285	dihydrofolate synthase activity
BF31_2206	COG1077	Cell shape determining protein MreB Mrl
BF31_2207	COG1792	Involved in formation and maintenance of cell shape
BF31_221	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF31_221	COG3409	Peptidoglycan-binding domain 1 protein
BF31_2210	COG2894	cell division
BF31_2211	COG0739	heme binding
BF31_2212	COG1994	Peptidase M50
BF31_2213	COG1530	ribonuclease E activity
BF31_2215	COG2868	ribosomal protein
BF31_2217	COG3290	protein histidine kinase activity
BF31_2218	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF31_2219	COG0745	RESPONSE REGULATOR receiver
BF31_2221	COG5002	protein histidine kinase activity
BF31_2222	COG1136	(ABC) transporter
BF31_2223	COG0577	efflux transmembrane transporter activity
BF31_2226	COG0077	Prephenate dehydratase
BF31_2227	COG2258	MOSC domain
BF31_2228	COG1827	regulation of RNA biosynthetic process
BF31_2229	COG1104	cysteine desulfurase activity
BF31_223	COG0561	phosphatase activity
BF31_2230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF31_2231	COG0157	Belongs to the NadC ModD family
BF31_2236	COG0640	Transcriptional regulator
BF31_2237	COG0697	spore germination
BF31_2238	COG0697	spore germination
BF31_2240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF31_2246	COG1862	Preprotein translocase
BF31_2248	COG2323	membrane
BF31_2249	COG2244	polysaccharide biosynthetic process
BF31_2251	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF31_2251	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF31_2252	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF31_2253	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF31_2253	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF31_2255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF31_2258	COG0124	histidyl-tRNA synthetase
BF31_226	COG3527	Alpha-acetolactate decarboxylase
BF31_2260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF31_2261	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF31_2262	COG1959	2 iron, 2 sulfur cluster binding
BF31_2263	COG1104	cysteine desulfurase activity
BF31_2264	COG0482	sulfurtransferase activity
BF31_2266	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF31_227	COG0028	Belongs to the TPP enzyme family
BF31_2270	COG0628	permease
BF31_2272	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF31_2276	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF31_2282	COG0768	penicillin binding
BF31_2287	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF31_2288	COG0626	cystathionine gamma-synthase activity
BF31_2289	COG1454	alcohol dehydrogenase
BF31_2289	COG1012	belongs to the aldehyde dehydrogenase family
BF31_2291	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_2299	COG2259	Doxx family
BF31_2300	COG2514	catechol 2,3-dioxygenase activity
BF31_2301	COG2514	catechol 2,3-dioxygenase activity
BF31_2303	COG3186	Phenylalanine-4-hydroxylase
BF31_2304	COG1404	Belongs to the peptidase S8 family
BF31_2311	COG2267	carboxylic ester hydrolase activity
BF31_2313	COG1785	Belongs to the alkaline phosphatase family
BF31_2315	COG2357	RelA SpoT domain protein
BF31_2316	COG0778	Nitroreductase
BF31_2318	COG1595	DNA-templated transcription, initiation
BF31_2321	COG1191	sigma factor activity
BF31_2324	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF31_2325	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF31_2327	COG1534	Rna-binding protein
BF31_2329	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF31_233	COG0189	ligase activity
BF31_2330	COG0799	negative regulation of ribosome biogenesis
BF31_2331	COG2226	methyltransferase
BF31_2332	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF31_2333	COG1596	polysaccharide export
BF31_2333	COG1555	photosystem II stabilization
BF31_2334	COG2131	deaminase
BF31_2335	COG2333	competence protein COMEC
BF31_2335	COG0658	competence protein
BF31_2337	COG1466	dna polymerase III delta subunit
BF31_2342	COG1733	regulation of RNA biosynthetic process
BF31_2343	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF31_2345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF31_2349	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF31_2350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF31_2352	COG1610	YqeY-like protein
BF31_2355	COG1702	phosphate starvation-inducible protein PhoH
BF31_2356	COG1480	7TM receptor with intracellular HD hydrolase
BF31_2358	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF31_2359	COG0295	cytidine deaminase activity
BF31_236	COG1126	abc transporter atp-binding protein
BF31_2360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF31_2363	COG0517	IMP dehydrogenase activity
BF31_2365	COG0358	DNA primase activity
BF31_2366	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF31_2367	COG2010	Cytochrome c
BF31_2368	COG2384	SAM-dependent methyltransferase
BF31_2369	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF31_237	COG0765	amino acid transport
BF31_2375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_2376	COG1121	(ABC) transporter
BF31_2377	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF31_2378	COG0735	belongs to the Fur family
BF31_238	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF31_2383	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF31_2384	COG0477	Major facilitator Superfamily
BF31_2386	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF31_2387	COG0573	inorganic phosphate transmembrane transporter activity
BF31_2388	COG0581	inorganic phosphate transmembrane transporter activity
BF31_2389	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF31_239	COG1132	(ABC) transporter
BF31_2390	COG0704	Plays a role in the regulation of phosphate uptake
BF31_2391	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF31_2394	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF31_2395	COG4483	Protein conserved in bacteria
BF31_2396	COG1940	carbohydrate kinase activity
BF31_2398	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_24	COG0095	Lipoate-protein ligase
BF31_240	COG1132	(ABC) transporter
BF31_2402	COG0626	cystathionine gamma-synthase activity
BF31_2403	COG0626	cystathionine gamma-synthase activity
BF31_2404	COG0646	methionine synthase
BF31_2404	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF31_2405	COG0646	methionine synthase
BF31_2405	COG1410	methionine synthase
BF31_2406	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF31_241	COG1132	(ABC) transporter
BF31_2416	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF31_2417	COG1459	type II secretion system
BF31_2419	COG4970	Tfp pilus assembly protein FimT
BF31_242	COG1012	belongs to the aldehyde dehydrogenase family
BF31_2430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF31_2436	COG1725	Transcriptional regulator
BF31_2437	COG1131	(ABC) transporter
BF31_244	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF31_2444	COG2076	Multidrug Resistance protein
BF31_2445	COG2076	Multidrug Resistance protein
BF31_2447	COG1609	Transcriptional regulator
BF31_2448	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_2449	COG0095	Lipoate-protein ligase
BF31_245	COG0531	amino acid
BF31_2454	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF31_2455	COG3872	metal-dependent enzyme
BF31_2458	COG0006	proline dipeptidase activity
BF31_2463	COG3854	ATPases associated with a variety of cellular activities
BF31_247	COG0753	catalase activity
BF31_247	COG0693	protein deglycase activity
BF31_2472	COG0511	ligase activity, forming carbon-carbon bonds
BF31_2473	COG0439	Biotin carboxylase
BF31_2474	COG1302	Protein conserved in bacteria
BF31_2479	COG0142	geranyltranstransferase activity
BF31_248	COG0693	protein deglycase activity
BF31_2481	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF31_2483	COG0497	DNA recombination
BF31_2484	COG0750	zinc metalloprotease
BF31_2485	COG0745	RESPONSE REGULATOR receiver
BF31_2487	COG3093	addiction module antidote protein HigA
BF31_2488	COG0584	glycerophosphoryl diester phosphodiesterase
BF31_2490	COG3829	transcription factor binding
BF31_2490	COG3290	protein histidine kinase activity
BF31_2491	COG0280	phosphate acetyltransferase
BF31_2492	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF31_2494	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF31_2495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF31_2496	COG0022	dehydrogenase e1 component
BF31_2497	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF31_2498	COG0772	Belongs to the SEDS family
BF31_2499	COG2816	NAD+ diphosphatase activity
BF31_25	COG1234	tRNA 3'-trailer cleavage
BF31_250	COG2211	Major facilitator Superfamily
BF31_2502	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF31_2503	COG0765	amino acid transport
BF31_2504	COG1126	abc transporter atp-binding protein
BF31_2505	COG4129	membrane
BF31_2506	COG1376	ErfK ybiS ycfS ynhG family protein
BF31_2508	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_2509	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF31_251	COG4533	DNA binding
BF31_2511	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF31_2514	COG1760	l-serine dehydratase
BF31_2515	COG1760	l-serine dehydratase
BF31_2516	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF31_2518	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_2519	COG0300	oxidoreductase activity
BF31_252	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF31_2522	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF31_2524	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF31_2528	COG1522	sequence-specific DNA binding
BF31_2530	COG0737	Belongs to the 5'-nucleotidase family
BF31_2533	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF31_2535	COG0156	8-amino-7-oxononanoate synthase activity
BF31_2536	COG1073	alpha beta
BF31_2536	COG2226	methyltransferase
BF31_2537	COG4106	trans-aconitate 2-methyltransferase activity
BF31_2538	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF31_254	COG1733	regulation of RNA biosynthetic process
BF31_2542	COG0307	riboflavin synthase, alpha
BF31_2543	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF31_2543	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF31_2546	COG1073	alpha beta
BF31_2547	COG0456	acetyltransferase
BF31_2548	COG1609	Transcriptional regulator
BF31_2549	COG2056	Na+-H+ antiporter family
BF31_255	COG2814	Major facilitator Superfamily
BF31_2550	COG0596	Alpha beta hydrolase
BF31_2552	COG0737	Belongs to the 5'-nucleotidase family
BF31_2552	COG4085	toxin activity
BF31_2552	COG1525	nuclease
BF31_2554	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF31_2554	COG0456	acetyltransferase
BF31_2555	COG0656	L-ascorbic acid biosynthetic process
BF31_2556	COG0667	Aldo Keto reductase
BF31_256	COG1309	transcriptional regulator
BF31_2560	COG1300	Membrane
BF31_2561	COG0735	belongs to the Fur family
BF31_2563	COG4974	Belongs to the 'phage' integrase family
BF31_2568	COG0598	Magnesium transport protein CorA
BF31_257	COG2076	Multidrug Resistance protein
BF31_2571	COG1846	Transcriptional regulator
BF31_2574	COG1131	(ABC) transporter
BF31_2575	COG1725	Transcriptional regulator
BF31_2576	COG1686	Belongs to the peptidase S11 family
BF31_258	COG2076	Multidrug Resistance protein
BF31_2580	COG0733	neurotransmitter:sodium symporter activity
BF31_2585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_2588	COG0697	spore germination
BF31_2589	COG0561	phosphatase activity
BF31_2590	COG4086	secreted protein
BF31_2591	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF31_2592	COG0456	acetyltransferase
BF31_2593	COG1547	Domain of unknown function (DUF309)
BF31_260	COG1522	sequence-specific DNA binding
BF31_2602	COG3711	transcriptional antiterminator
BF31_2603	COG1263	PTS System
BF31_2603	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_2603	COG2190	(PTS) system
BF31_2608	COG0778	Nitroreductase
BF31_2609	COG3706	GGDEF domain
BF31_261	COG0697	spore germination
BF31_2610	COG2084	Dehydrogenase
BF31_2611	COG2084	Dehydrogenase
BF31_2614	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF31_2618	COG0436	Aminotransferase
BF31_2619	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF31_2623	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_2624	COG1695	Transcriptional regulator
BF31_2631	COG0183	Belongs to the thiolase family
BF31_2639	COG3842	ATPase activity
BF31_264	COG2259	Doxx family
BF31_2640	COG0366	Alpha amylase catalytic
BF31_2642	COG2182	Extracellular solute-binding protein
BF31_2643	COG1175	transmembrane transport
BF31_2644	COG3833	ABC-type maltose transport systems, permease component
BF31_2645	COG1609	Transcriptional regulator
BF31_2646	COG0436	Aminotransferase
BF31_2648	COG2205	protein histidine kinase activity
BF31_2650	COG3209	COG3209 Rhs family protein
BF31_2654	COG2814	Major facilitator Superfamily
BF31_266	COG1263	PTS System
BF31_266	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_2661	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF31_2663	COG1408	metallophosphoesterase
BF31_2664	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_2665	COG2200	EAL domain
BF31_2668	COG4703	Protein of unknown function (DUF1797)
BF31_2670	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF31_2672	COG0517	IMP dehydrogenase activity
BF31_2673	COG0583	DNA-binding transcription factor activity
BF31_2677	COG0569	domain protein
BF31_2678	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF31_268	COG1737	Transcriptional regulator
BF31_2680	COG0561	phosphatase activity
BF31_2681	COG0242	peptide deformylase activity
BF31_2683	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF31_2684	COG0022	dehydrogenase e1 component
BF31_2685	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF31_2694	COG1982	Orn Lys Arg decarboxylase major
BF31_2698	COG0483	inositol monophosphate 1-phosphatase activity
BF31_27	COG1609	Transcriptional regulator
BF31_270	COG0475	glutathione-regulated potassium exporter activity
BF31_2703	COG4896	Protein conserved in bacteria
BF31_2705	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF31_2706	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF31_2707	COG4838	Belongs to the UPF0358 family
BF31_2708	COG0772	Belongs to the SEDS family
BF31_2709	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF31_271	COG0531	amino acid
BF31_2716	COG3336	cytochrome c oxidase
BF31_2719	COG2340	Cysteine-rich secretory protein family
BF31_2722	COG0406	alpha-ribazole phosphatase activity
BF31_2723	COG3679	Belongs to the UPF0342 family
BF31_2727	COG0742	ribosomal rna small subunit methyltransferase
BF31_2728	COG3314	Sporulation integral membrane protein YlbJ
BF31_2730	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF31_2731	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF31_2733	COG0582	viral genome integration into host DNA
BF31_2737	COG1396	sequence-specific DNA binding
BF31_2741	COG1396	sequence-specific DNA binding
BF31_2747	COG1484	DNA-dependent DNA replication
BF31_2752	COG1191	sigma factor activity
BF31_2767	COG0582	viral genome integration into host DNA
BF31_277	COG0586	Pfam SNARE associated Golgi protein
BF31_2772	COG1802	Transcriptional regulator
BF31_2772	COG4626	Terminase
BF31_2791	COG4824	toxin secretion phage lysis holin
BF31_2801	COG1399	metal-binding, possibly nucleic acid-binding protein
BF31_2805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF31_2808	COG4839	cell division protein FtsL
BF31_2810	COG0768	penicillin binding
BF31_2811	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF31_2814	COG0772	Belongs to the SEDS family
BF31_2815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF31_2816	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF31_2817	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF31_2818	COG0849	cell division
BF31_2819	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF31_2821	COG1191	sigma factor activity
BF31_2822	COG1191	sigma factor activity
BF31_2823	COG1873	PFAM PRC-barrel domain
BF31_2825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF31_2827	COG0762	integral membrane protein
BF31_2828	COG2302	S4 RNA-binding domain
BF31_2829	COG3599	regulation of cell shape
BF31_2830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF31_2833	COG0564	pseudouridine synthase activity
BF31_2838	COG0505	Belongs to the CarA family
BF31_284	COG3546	catalase activity
BF31_2846	COG3069	C4-dicarboxylate transmembrane transporter activity
BF31_2849	COG0006	proline dipeptidase activity
BF31_285	COG1114	Component of the transport system for branched-chain amino acids
BF31_2851	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF31_2852	COG1561	YicC-like family, N-terminal region
BF31_2854	COG0194	GDP metabolic process
BF31_2856	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF31_2857	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF31_2858	COG0242	peptide deformylase activity
BF31_2860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF31_2860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF31_2862	COG0631	protein serine/threonine phosphatase activity
BF31_2863	COG0515	serine threonine protein kinase
BF31_2863	COG2815	serine threonine protein kinase
BF31_2864	COG1162	GTPase activity
BF31_2865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF31_2866	COG1564	THIamine pyrophosphokinase
BF31_2868	COG1302	Protein conserved in bacteria
BF31_2869	COG1461	Dihydroxyacetone kinase
BF31_2870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF31_2873	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF31_2874	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_2877	COG1196	nuclear chromosome segregation
BF31_2878	COG0552	protein localization to endoplasmic reticulum
BF31_288	COG5522	Integral membrane protein (intg_mem_TP0381)
BF31_2880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF31_2882	COG1837	Belongs to the UPF0109 family
BF31_2890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF31_2892	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF31_2894	COG4974	Belongs to the 'phage' integrase family
BF31_290	COG1136	(ABC) transporter
BF31_2900	COG0528	UMP kinase activity
BF31_2902	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF31_2903	COG4589	Belongs to the CDS family
BF31_2904	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF31_2905	COG0750	zinc metalloprotease
BF31_2909	COG0195	Participates in both transcription termination and antitermination
BF31_291	COG0577	efflux transmembrane transporter activity
BF31_2910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF31_2911	COG1358	cellular component organization or biogenesis
BF31_2913	COG1550	Protein conserved in bacteria
BF31_2915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF31_2916	COG0196	riboflavin kinase activity
BF31_2919	COG0726	polysaccharide deacetylase
BF31_292	COG3584	3D domain protein
BF31_292	COG1388	LysM domain
BF31_2920	COG0612	Peptidase, M16
BF31_2921	COG1873	PFAM PRC-barrel domain
BF31_2922	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF31_2923	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF31_2924	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF31_2925	COG0527	aspartate kinase activity
BF31_2927	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF31_2928	COG0740	serine-type endopeptidase activity
BF31_2930	COG1674	ftsk spoiiie
BF31_2931	COG2188	Transcriptional regulator
BF31_2937	COG0612	Peptidase, M16
BF31_2938	COG0612	Peptidase, M16
BF31_2939	COG0300	oxidoreductase activity
BF31_2942	COG1426	Protein conserved in bacteria
BF31_2943	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF31_2948	COG1692	metallophosphoesterase
BF31_2949	COG2359	stage V sporulation protein S
BF31_2951	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF31_2951	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF31_2952	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF31_2953	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF31_2954	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF31_296	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF31_2963	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF31_2965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF31_2966	COG1368	sulfuric ester hydrolase activity
BF31_2967	COG0562	UDP-galactopyranose mutase
BF31_2968	COG3773	Cell wall hydrolase
BF31_2969	COG1404	Belongs to the peptidase S8 family
BF31_297	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF31_2972	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF31_2973	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF31_2973	COG0596	Alpha beta hydrolase
BF31_2974	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_2975	COG1380	Effector of murein hydrolase LrgA
BF31_2976	COG1346	cytolysis
BF31_2979	COG5001	Diguanylate cyclase
BF31_2979	COG3300	MHYT domain
BF31_298	COG3711	transcriptional antiterminator
BF31_298	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF31_2980	COG0346	lactoylglutathione lyase activity
BF31_2981	COG2267	carboxylic ester hydrolase activity
BF31_2984	COG2364	Membrane
BF31_2986	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF31_2987	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF31_2988	COG2169	Transcriptional regulator
BF31_2989	COG0708	Exodeoxyribonuclease III
BF31_2991	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_2992	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_2993	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_2994	COG1120	ATPase activity
BF31_2995	COG2819	hydrolase of the alpha beta superfamily
BF31_2997	COG1937	Protein conserved in bacteria
BF31_2998	COG2608	mercury ion transmembrane transporter activity
BF31_2999	COG2217	Heavy metal translocating P-type atpase
BF31_3001	COG2116	formate transmembrane transporter activity
BF31_3002	COG1408	metallophosphoesterase
BF31_3005	COG1113	amino acid transport
BF31_3008	COG2322	membrane
BF31_3009	COG1979	alcohol dehydrogenase
BF31_301	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF31_3010	COG1979	alcohol dehydrogenase
BF31_3011	COG1349	DNA-binding transcription factor activity
BF31_3012	COG1105	Belongs to the carbohydrate kinase PfkB family
BF31_3013	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF31_3013	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF31_3013	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF31_3014	COG1388	LysM domain
BF31_3014	COG3584	3D domain protein
BF31_302	COG0604	alcohol dehydrogenase
BF31_3021	COG0464	growth
BF31_3022	COG2860	membrane
BF31_3023	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF31_3024	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF31_3025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF31_3026	COG0789	Transcriptional regulator
BF31_3027	COG0174	glutamine synthetase
BF31_303	COG1316	TRANSCRIPTIONal
BF31_3032	COG1396	sequence-specific DNA binding
BF31_3048	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF31_305	COG0730	response to heat
BF31_3056	COG1595	DNA-templated transcription, initiation
BF31_306	COG2210	Belongs to the sulfur carrier protein TusA family
BF31_308	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_3088	COG4824	toxin secretion phage lysis holin
BF31_3089	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF31_3089	COG1388	LysM domain
BF31_3089	COG3409	Peptidoglycan-binding domain 1 protein
BF31_3097	COG1695	Transcriptional regulator
BF31_310	COG0425	Belongs to the sulfur carrier protein TusA family
BF31_3101	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF31_3103	COG0737	Belongs to the 5'-nucleotidase family
BF31_3106	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF31_3107	COG3639	organic phosphonate transmembrane transporter activity
BF31_311	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_311	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_3113	COG1132	(ABC) transporter
BF31_3114	COG1132	(ABC) transporter
BF31_3117	COG3409	Peptidoglycan-binding domain 1 protein
BF31_3117	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF31_3119	COG0730	response to heat
BF31_312	COG0425	Belongs to the sulfur carrier protein TusA family
BF31_312	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_3122	COG1346	cytolysis
BF31_3123	COG1380	Effector of murein hydrolase LrgA
BF31_3124	COG0583	DNA-binding transcription factor activity
BF31_3126	COG0785	Cytochrome C biogenesis protein
BF31_3127	COG4846	Membrane protein involved in cytochrome C biogenesis
BF31_313	COG1937	Protein conserved in bacteria
BF31_3137	COG2226	methyltransferase
BF31_314	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF31_3142	COG0010	Belongs to the arginase family
BF31_3143	COG1329	Transcriptional regulator
BF31_3144	COG1902	pentaerythritol trinitrate reductase activity
BF31_3145	COG0069	glutamate synthase activity
BF31_3146	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF31_3147	COG0346	lactoylglutathione lyase activity
BF31_3148	COG0400	carboxylic ester hydrolase activity
BF31_3149	COG5002	protein histidine kinase activity
BF31_3151	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_3160	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_3161	COG1268	BioY protein
BF31_3162	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_3163	COG0183	Belongs to the thiolase family
BF31_3166	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF31_3168	COG2211	Major facilitator Superfamily
BF31_3171	COG0726	polysaccharide deacetylase
BF31_3173	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF31_3174	COG2274	protein secretion by the type I secretion system
BF31_3176	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF31_3182	COG0824	Thioesterase
BF31_3183	COG4841	protein insertion into membrane
BF31_3184	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF31_3187	COG0745	RESPONSE REGULATOR receiver
BF31_3188	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF31_3189	COG1832	CoA-binding protein
BF31_319	COG2719	SpoVR family
BF31_3190	COG0187	DNA topoisomerase II activity
BF31_3191	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF31_3192	COG0673	inositol 2-dehydrogenase activity
BF31_3194	COG1131	(ABC) transporter
BF31_3198	COG1595	DNA-templated transcription, initiation
BF31_32	COG1511	domain protein
BF31_320	COG0778	Nitroreductase
BF31_3200	COG1316	TRANSCRIPTIONal
BF31_3201	COG1301	dicarboxylic acid transport
BF31_3202	COG4166	transmembrane transport
BF31_3203	COG4166	transmembrane transport
BF31_3204	COG4166	transmembrane transport
BF31_3205	COG2226	methyltransferase
BF31_3213	COG0697	spore germination
BF31_3215	COG3383	formate dehydrogenase (NAD+) activity
BF31_3216	COG2427	Protein of unknown function (DUF1641)
BF31_3217	COG5609	conserved protein (DUF2294)
BF31_3218	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF31_3220	COG2116	formate transmembrane transporter activity
BF31_3221	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF31_3222	COG0303	'Molybdopterin
BF31_3223	COG0314	molybdopterin synthase activity
BF31_3225	COG0489	protein tyrosine kinase activity
BF31_3228	COG3326	Membrane
BF31_3229	COG2962	Rard protein
BF31_3230	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF31_3231	COG1657	PFAM Prenyltransferase squalene oxidase
BF31_3233	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3234	COG1012	belongs to the aldehyde dehydrogenase family
BF31_3236	COG4145	pantothenate transmembrane transporter activity
BF31_3239	COG0165	Argininosuccinate lyase
BF31_3241	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3247	COG0716	FMN binding
BF31_3249	COG1278	Cold shock
BF31_3255	COG2720	vancomycin resistance protein
BF31_3256	COG2514	catechol 2,3-dioxygenase activity
BF31_3258	COG1285	pathogenesis
BF31_3260	COG1024	Enoyl-CoA hydratase
BF31_3261	COG1216	Glycosyl transferase, family 2
BF31_3267	COG0277	FAD linked oxidase domain protein
BF31_3268	COG0385	Bile acid
BF31_3270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF31_3271	COG2808	Putative FMN-binding domain
BF31_3274	COG0457	Tetratricopeptide repeat
BF31_3276	COG0604	alcohol dehydrogenase
BF31_3277	COG0640	Transcriptional regulator
BF31_328	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF31_3281	COG0584	glycerophosphoryl diester phosphodiesterase
BF31_3287	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF31_3288	COG1164	Oligoendopeptidase f
BF31_3289	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF31_329	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF31_3292	COG1193	negative regulation of DNA recombination
BF31_3296	COG0583	DNA-binding transcription factor activity
BF31_33	COG1309	transcriptional regulator
BF31_3302	COG0384	phenazine biosynthesis protein PhzF
BF31_3303	COG3739	integral membrane protein
BF31_3304	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_3305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_3307	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_331	COG1609	Transcriptional regulator
BF31_3311	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF31_3312	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF31_3318	COG2814	Major facilitator Superfamily
BF31_3319	COG1113	amino acid transport
BF31_332	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_332	COG1263	PTS System
BF31_3320	COG0604	alcohol dehydrogenase
BF31_3327	COG2072	flavoprotein involved in K transport
BF31_333	COG1621	beta-fructofuranosidase activity
BF31_3334	COG3409	Peptidoglycan-binding domain 1 protein
BF31_3334	COG3757	hydrolase, family 25
BF31_3335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_3338	COG1151	hydroxylamine reductase activity
BF31_334	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF31_3343	COG3152	Membrane
BF31_3347	COG1309	transcriptional regulator
BF31_3350	COG1191	sigma factor activity
BF31_3353	COG0726	polysaccharide deacetylase
BF31_3357	COG1733	regulation of RNA biosynthetic process
BF31_3358	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF31_3360	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_3362	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3364	COG0384	phenazine biosynthesis protein PhzF
BF31_3368	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_3371	COG1733	regulation of RNA biosynthetic process
BF31_3372	COG1733	regulation of RNA biosynthetic process
BF31_3373	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF31_3375	COG0673	inositol 2-dehydrogenase activity
BF31_3376	COG2188	Transcriptional regulator
BF31_3377	COG1733	regulation of RNA biosynthetic process
BF31_3378	COG1393	Belongs to the ArsC family
BF31_338	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3383	COG0814	amino acid
BF31_3384	COG0346	lactoylglutathione lyase activity
BF31_3387	COG2814	Major facilitator Superfamily
BF31_3388	COG0656	L-ascorbic acid biosynthetic process
BF31_339	COG2252	PERMEase
BF31_3393	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3396	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF31_3397	COG0604	alcohol dehydrogenase
BF31_3398	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF31_3399	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF31_3401	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF31_3402	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF31_3404	COG1070	Carbohydrate kinase
BF31_3405	COG2706	6-phosphogluconolactonase activity
BF31_3406	COG3813	Protein conserved in bacteria
BF31_3407	COG1357	PFAM Pentapeptide repeats (8 copies)
BF31_3408	COG0697	spore germination
BF31_3409	COG0789	Transcriptional regulator
BF31_3410	COG1253	flavin adenine dinucleotide binding
BF31_3416	COG0477	Major facilitator Superfamily
BF31_3418	COG2226	methyltransferase
BF31_342	COG1846	Transcriptional regulator
BF31_3422	COG0628	permease
BF31_3423	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF31_3424	COG0180	Tryptophanyl-tRNA synthetase
BF31_3426	COG1136	(ABC) transporter
BF31_3428	COG0110	maltose O-acetyltransferase activity
BF31_3429	COG0738	Major facilitator superfamily
BF31_343	COG2814	Major facilitator Superfamily
BF31_3430	COG1940	carbohydrate kinase activity
BF31_3431	COG0346	lactoylglutathione lyase activity
BF31_3438	COG1011	Hydrolase
BF31_344	COG2205	protein histidine kinase activity
BF31_3443	COG1131	(ABC) transporter
BF31_3445	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_3449	COG0778	Nitroreductase
BF31_3450	COG1733	regulation of RNA biosynthetic process
BF31_3453	COG0124	histidyl-tRNA synthetase
BF31_3454	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF31_3455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF31_3456	COG3620	sequence-specific DNA binding
BF31_3459	COG2356	endonuclease I
BF31_3460	COG1288	antiporter activity
BF31_3461	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF31_3464	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF31_3465	COG1122	ATPase activity
BF31_3471	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF31_3473	COG2031	fatty acid transporter
BF31_3475	COG1309	transcriptional regulator
BF31_3476	COG2076	Multidrug Resistance protein
BF31_3480	COG1131	(ABC) transporter
BF31_3481	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF31_3484	COG2814	Major facilitator Superfamily
BF31_3485	COG1846	Transcriptional regulator
BF31_3487	COG0477	Major facilitator Superfamily
BF31_3498	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_3498	COG2207	Transcriptional regulator
BF31_3499	COG0662	Cupin 2, conserved barrel domain protein
BF31_3502	COG1595	DNA-templated transcription, initiation
BF31_3506	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF31_3509	COG0531	amino acid
BF31_351	COG0351	phosphomethylpyrimidine kinase
BF31_3510	COG1522	sequence-specific DNA binding
BF31_3511	COG1335	isochorismatase
BF31_3513	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF31_3514	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF31_3515	COG1760	l-serine dehydratase
BF31_3516	COG1760	l-serine dehydratase
BF31_3517	COG0814	amino acid
BF31_352	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF31_3520	COG1309	transcriptional regulator
BF31_3521	COG2814	Major facilitator Superfamily
BF31_3522	COG2184	nucleotidyltransferase activity
BF31_3525	COG0534	Mate efflux family protein
BF31_3530	COG0840	transmembrane signaling receptor activity
BF31_3533	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF31_3537	COG0457	Tetratricopeptide repeat
BF31_3538	COG1609	Transcriptional regulator
BF31_3539	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF31_354	COG2104	thiamine diphosphate biosynthetic process
BF31_3540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF31_3541	COG0561	phosphatase activity
BF31_3542	COG0673	inositol 2-dehydrogenase activity
BF31_3543	COG0738	Major facilitator superfamily
BF31_3547	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF31_3549	COG0583	DNA-binding transcription factor activity
BF31_355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF31_3551	COG1139	Iron-sulfur cluster binding protein
BF31_3552	COG1556	Lactate utilization protein
BF31_3553	COG2271	Major facilitator Superfamily
BF31_3554	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_3555	COG2808	Putative FMN-binding domain
BF31_3556	COG0456	acetyltransferase
BF31_3557	COG1846	Transcriptional regulator
BF31_3558	COG2364	Membrane
BF31_356	COG0352	thiamine-phosphate diphosphorylase activity
BF31_3560	COG5002	protein histidine kinase activity
BF31_3560	COG3850	Histidine kinase
BF31_3563	COG0577	efflux transmembrane transporter activity
BF31_3564	COG1136	(ABC) transporter
BF31_3567	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF31_3568	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_357	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF31_3570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF31_3571	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_3574	COG1476	TRANSCRIPTIONal
BF31_358	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF31_3580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF31_3585	COG5002	protein histidine kinase activity
BF31_3585	COG3850	Histidine kinase
BF31_3586	COG0745	RESPONSE REGULATOR receiver
BF31_359	COG1116	anion transmembrane transporter activity
BF31_3591	COG2814	Major facilitator Superfamily
BF31_360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF31_3603	COG0346	lactoylglutathione lyase activity
BF31_3606	COG1522	sequence-specific DNA binding
BF31_3609	COG0443	Heat shock 70 kDa protein
BF31_3613	COG0640	Transcriptional regulator
BF31_3614	COG0346	lactoylglutathione lyase activity
BF31_3615	COG0798	PFAM Bile acid sodium symporter
BF31_3621	COG1121	(ABC) transporter
BF31_3622	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF31_3623	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF31_3624	COG2267	carboxylic ester hydrolase activity
BF31_3625	COG1575	Belongs to the MenA family. Type 1 subfamily
BF31_3627	COG5609	conserved protein (DUF2294)
BF31_3628	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF31_3630	COG0288	reversible hydration of carbon dioxide
BF31_3631	COG0415	Belongs to the DNA photolyase family
BF31_3638	COG0598	Magnesium transport protein CorA
BF31_3639	COG0598	Magnesium transport protein CorA
BF31_364	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF31_3640	COG1846	Transcriptional regulator
BF31_3641	COG0583	DNA-binding transcription factor activity
BF31_3646	COG1335	isochorismatase
BF31_3647	COG2267	carboxylic ester hydrolase activity
BF31_3648	COG0753	catalase activity
BF31_3649	COG0737	Belongs to the 5'-nucleotidase family
BF31_3655	COG1115	amino acid carrier protein
BF31_3657	COG2066	Belongs to the glutaminase family
BF31_3658	COG4191	Histidine kinase
BF31_3659	COG4191	Histidine kinase
BF31_3660	COG0784	Response regulator, receiver
BF31_3661	COG0697	spore germination
BF31_3662	COG0531	amino acid
BF31_3666	COG0281	malic enzyme
BF31_3668	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF31_3669	COG1114	Component of the transport system for branched-chain amino acids
BF31_3670	COG0531	amino acid
BF31_3671	COG0322	excinuclease ABC activity
BF31_3673	COG1396	sequence-specific DNA binding
BF31_3674	COG0252	asparaginase activity
BF31_3675	COG1027	Aspartate ammonia-lyase
BF31_3678	COG1063	alcohol dehydrogenase
BF31_3684	COG1113	amino acid transport
BF31_3685	COG1113	amino acid transport
BF31_3686	COG1280	lysine exporter protein (LysE YggA)
BF31_3687	COG3403	YqcI/YcgG family
BF31_3689	COG5577	PFAM Coat F domain
BF31_3692	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_3693	COG3848	Pyruvate phosphate dikinase
BF31_3693	COG0574	Belongs to the PEP-utilizing enzyme family
BF31_3696	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF31_3703	COG1960	acyl-CoA dehydrogenase activity
BF31_3705	COG0640	Transcriptional regulator
BF31_3706	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF31_3709	COG1414	Transcriptional regulator
BF31_3710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF31_3711	COG1984	allophanate hydrolase subunit 2
BF31_3717	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF31_3727	COG4335	DNA alkylation repair
BF31_3729	COG0833	amino acid
BF31_3731	COG0730	response to heat
BF31_3737	COG0596	Alpha beta hydrolase
BF31_3738	COG0745	RESPONSE REGULATOR receiver
BF31_3739	COG0642	Histidine kinase
BF31_3743	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_3747	COG0456	acetyltransferase
BF31_3748	COG2207	Transcriptional regulator
BF31_3753	COG1136	(ABC) transporter
BF31_3753	COG0577	efflux transmembrane transporter activity
BF31_3755	COG1725	Transcriptional regulator
BF31_3762	COG1846	Transcriptional regulator
BF31_3763	COG0778	Nitroreductase
BF31_3765	COG0714	Associated with various cellular activities
BF31_3771	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF31_3773	COG0753	catalase activity
BF31_3777	COG0463	Glycosyl transferase, family 2
BF31_3782	COG0463	Glycosyl transferase, family 2
BF31_3787	COG0714	Associated with various cellular activities
BF31_3791	COG0346	lactoylglutathione lyase activity
BF31_3792	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_3794	COG3279	Response regulator of the LytR AlgR family
BF31_3796	COG4377	Putative membrane peptidase family (DUF2324)
BF31_3799	COG3655	Transcriptional regulator
BF31_3801	COG1785	Belongs to the alkaline phosphatase family
BF31_3802	COG3239	Fatty acid desaturase
BF31_3803	COG1690	Belongs to the RtcB family
BF31_3804	COG0833	amino acid
BF31_3805	COG1414	Transcriptional regulator
BF31_3806	COG4187	Peptidase family M20/M25/M40
BF31_3807	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF31_3808	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF31_3810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_3814	COG2329	Antibiotic biosynthesis monooxygenase
BF31_3821	COG1070	Carbohydrate kinase
BF31_3822	COG2390	Transcriptional regulator
BF31_3824	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF31_3826	COG1879	ABC-type sugar transport system periplasmic component
BF31_3832	COG1595	DNA-templated transcription, initiation
BF31_3834	COG3584	3D domain protein
BF31_3834	COG1388	LysM domain
BF31_3842	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF31_3842	COG1605	Chorismate mutase
BF31_3843	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF31_3844	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF31_3845	COG0287	Prephenate dehydrogenase
BF31_3848	COG1309	transcriptional regulator
BF31_3849	COG2409	Drug exporters of the RND superfamily
BF31_3849	COG1033	growth of symbiont in host cell
BF31_3850	COG2409	Drug exporters of the RND superfamily
BF31_3850	COG1033	growth of symbiont in host cell
BF31_3852	COG0488	(ABC) transporter
BF31_3853	COG1368	sulfuric ester hydrolase activity
BF31_3854	COG0861	Integral membrane protein TerC family
BF31_3856	COG0726	polysaccharide deacetylase
BF31_3858	COG4912	Dna alkylation repair
BF31_3862	COG2318	DinB family
BF31_3863	COG0697	spore germination
BF31_3868	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF31_3876	COG1116	anion transmembrane transporter activity
BF31_3877	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF31_3878	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF31_3879	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF31_3881	COG0628	permease
BF31_389	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF31_3890	COG1131	(ABC) transporter
BF31_3894	COG5146	pantothenate kinase activity
BF31_3895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF31_3896	COG0436	Aminotransferase
BF31_3903	COG2226	methyltransferase
BF31_3906	COG2261	transglycosylase associated protein
BF31_391	COG0581	inorganic phosphate transmembrane transporter activity
BF31_3910	COG2814	Major facilitator Superfamily
BF31_3910	COG0477	Major facilitator Superfamily
BF31_3911	COG4533	DNA binding
BF31_3912	COG0789	Transcriptional regulator
BF31_3913	COG1664	Polymer-forming cytoskeletal
BF31_3916	COG2814	Major facilitator Superfamily
BF31_3919	COG1307	EDD domain protein, DegV family
BF31_392	COG0573	inorganic phosphate transmembrane transporter activity
BF31_3922	COG1164	Oligoendopeptidase f
BF31_3929	COG0745	RESPONSE REGULATOR receiver
BF31_393	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF31_3930	COG5002	protein histidine kinase activity
BF31_3931	COG2936	dipeptidyl-peptidase activity
BF31_3939	COG4948	Mandelate Racemase Muconate Lactonizing
BF31_394	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF31_394	COG1918	ferrous iron import across plasma membrane
BF31_3941	COG4166	transmembrane transport
BF31_3942	COG0519	Catalyzes the synthesis of GMP from XMP
BF31_3943	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF31_3946	COG0586	Pfam SNARE associated Golgi protein
BF31_395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF31_3953	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF31_3954	COG3938	Belongs to the proline racemase family
BF31_3956	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF31_3957	COG1012	belongs to the aldehyde dehydrogenase family
BF31_3958	COG1115	amino acid carrier protein
BF31_3959	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF31_396	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF31_3961	COG3397	chitin binding
BF31_3966	COG4637	Psort location Cytoplasmic, score
BF31_3970	COG0514	ATP-dependent DNA helicase (RecQ)
BF31_3971	COG2105	PFAM AIG2 family protein
BF31_3974	COG3973	AAA domain
BF31_398	COG0531	amino acid
BF31_3984	COG0658	competence protein
BF31_3984	COG2333	competence protein COMEC
BF31_3989	COG2205	protein histidine kinase activity
BF31_399	COG0697	spore germination
BF31_3993	COG3397	chitin binding
BF31_3994	COG2153	protein acetylation
BF31_3995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF31_3998	COG0740	serine-type endopeptidase activity
BF31_400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF31_4000	COG4175	Glycine betaine
BF31_4000	COG0517	IMP dehydrogenase activity
BF31_4001	COG4176	ABC-type proline glycine betaine transport system permease component
BF31_4007	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF31_4007	COG0456	acetyltransferase
BF31_4008	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_4010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF31_4011	COG0022	dehydrogenase e1 component
BF31_4012	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF31_4013	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF31_4017	COG1959	2 iron, 2 sulfur cluster binding
BF31_4021	COG1349	DNA-binding transcription factor activity
BF31_4025	COG3284	Transcriptional regulator
BF31_403	COG4990	cell redox homeostasis
BF31_4031	COG1309	transcriptional regulator
BF31_4032	COG3844	kynureninase activity
BF31_4033	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF31_4034	COG3483	tryptophan 2,3-dioxygenase activity
BF31_4037	COG3409	Peptidoglycan-binding domain 1 protein
BF31_4037	COG3773	Cell wall hydrolase
BF31_4038	COG2959	enzyme of heme biosynthesis
BF31_404	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF31_4041	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_4042	COG4129	membrane
BF31_4048	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_4049	COG0697	spore germination
BF31_405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF31_4051	COG0201	protein transport
BF31_4055	COG3227	Zinc metalloprotease (Elastase)
BF31_4056	COG1523	belongs to the glycosyl hydrolase 13 family
BF31_4059	COG0076	glutamate decarboxylase activity
BF31_4064	COG1011	Hydrolase
BF31_4069	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF31_4077	COG0322	excinuclease ABC activity
BF31_408	COG0569	domain protein
BF31_408	COG0475	glutathione-regulated potassium exporter activity
BF31_4080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF31_4086	COG4667	esterase of the alpha-beta hydrolase superfamily
BF31_4092	COG3878	Protein conserved in bacteria
BF31_4099	COG1051	belongs to the nudix hydrolase family
BF31_4100	COG0592	DNA-directed DNA polymerase activity
BF31_4101	COG2816	NAD+ diphosphatase activity
BF31_4103	COG2223	nitrite transmembrane transporter activity
BF31_4110	COG0697	spore germination
BF31_4111	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_4112	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_4115	COG0584	glycerophosphoryl diester phosphodiesterase
BF31_4119	COG2814	Major facilitator Superfamily
BF31_4124	COG0693	protein deglycase activity
BF31_413	COG2252	PERMEase
BF31_4130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF31_4133	COG0604	alcohol dehydrogenase
BF31_4136	COG2205	protein histidine kinase activity
BF31_4139	COG1122	ATPase activity
BF31_414	COG1113	amino acid transport
BF31_4141	COG1794	racemase activity, acting on amino acids and derivatives
BF31_4142	COG1819	glycosyl
BF31_4144	COG5002	protein histidine kinase activity
BF31_4146	COG0561	phosphatase activity
BF31_4153	COG2124	cytochrome p450
BF31_4169	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF31_417	COG1114	Component of the transport system for branched-chain amino acids
BF31_4171	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_4172	COG0460	homoserine dehydrogenase
BF31_4176	COG0577	efflux transmembrane transporter activity
BF31_4177	COG0577	efflux transmembrane transporter activity
BF31_4178	COG1136	(ABC) transporter
BF31_418	COG3104	oligopeptide transport
BF31_4183	COG2205	protein histidine kinase activity
BF31_4185	COG0745	RESPONSE REGULATOR receiver
BF31_4187	COG3773	Cell wall hydrolase
BF31_4190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF31_4191	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF31_4194	COG1063	alcohol dehydrogenase
BF31_4196	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_42	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF31_4200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF31_4204	COG2814	Major facilitator Superfamily
BF31_4206	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF31_4209	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF31_4209	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF31_421	COG1476	TRANSCRIPTIONal
BF31_4214	COG3227	Zinc metalloprotease (Elastase)
BF31_4218	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF31_422	COG3584	3D domain protein
BF31_422	COG1388	LysM domain
BF31_4223	COG1686	Belongs to the peptidase S11 family
BF31_4224	COG2318	DinB family
BF31_4226	COG0572	uridine kinase
BF31_4227	COG1247	-acetyltransferase
BF31_4229	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF31_423	COG0840	transmembrane signaling receptor activity
BF31_4230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF31_4231	COG1024	Enoyl-CoA hydratase
BF31_4232	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF31_4233	COG0511	ligase activity, forming carbon-carbon bonds
BF31_4234	COG0439	Biotin carboxylase
BF31_4235	COG1960	acyl-CoA dehydrogenase activity
BF31_4238	COG1309	transcriptional regulator
BF31_424	COG1968	undecaprenyl-diphosphatase activity
BF31_4240	COG1131	(ABC) transporter
BF31_4243	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF31_4244	COG1252	NADH dehydrogenase
BF31_4246	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_4250	COG1309	transcriptional regulator
BF31_4255	COG1876	peptidase activity
BF31_4258	COG1476	TRANSCRIPTIONal
BF31_4259	COG0457	Tetratricopeptide repeat
BF31_4261	COG0737	Belongs to the 5'-nucleotidase family
BF31_4262	COG0737	Belongs to the 5'-nucleotidase family
BF31_4266	COG3718	enzyme involved in inositol metabolism
BF31_4270	COG1012	belongs to the aldehyde dehydrogenase family
BF31_4272	COG0673	inositol 2-dehydrogenase activity
BF31_4273	COG2814	Major facilitator Superfamily
BF31_4274	COG1609	Transcriptional regulator
BF31_4275	COG0671	phosphoesterase, PA-phosphatase related
BF31_4276	COG2367	Beta-lactamase
BF31_4279	COG0768	penicillin binding
BF31_4281	COG1595	DNA-templated transcription, initiation
BF31_4285	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF31_429	COG3568	Endonuclease Exonuclease Phosphatase
BF31_4293	COG1846	Transcriptional regulator
BF31_4294	COG3961	Belongs to the TPP enzyme family
BF31_4295	COG2226	methyltransferase
BF31_4297	COG3615	Tellurite resistance protein tehB
BF31_4297	COG0500	methyltransferase
BF31_4298	COG0577	efflux transmembrane transporter activity
BF31_4298	COG1136	(ABC) transporter
BF31_43	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF31_4301	COG1309	transcriptional regulator
BF31_4306	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_4309	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF31_4310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF31_4311	COG2971	BadF BadG BcrA BcrD
BF31_4316	COG1649	PFAM Uncharacterised BCR, COG1649
BF31_432	COG1063	alcohol dehydrogenase
BF31_4321	COG1595	DNA-templated transcription, initiation
BF31_4326	COG1396	sequence-specific DNA binding
BF31_4330	COG1132	(ABC) transporter
BF31_4331	COG1132	(ABC) transporter
BF31_4334	COG2258	MOSC domain
BF31_4335	COG0583	DNA-binding transcription factor activity
BF31_4338	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF31_4339	COG0583	DNA-binding transcription factor activity
BF31_4347	COG0561	phosphatase activity
BF31_4348	COG0010	Belongs to the arginase family
BF31_4351	COG1278	Cold shock
BF31_4353	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_436	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF31_4361	COG1247	-acetyltransferase
BF31_4368	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF31_437	COG1879	ABC-type sugar transport system periplasmic component
BF31_4377	COG2226	methyltransferase
BF31_438	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF31_4382	COG2814	Major facilitator Superfamily
BF31_4383	COG0596	Alpha beta hydrolase
BF31_4387	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF31_4388	COG1187	pseudouridine synthase activity
BF31_4389	COG2329	Antibiotic biosynthesis monooxygenase
BF31_439	COG1129	ABC transporter
BF31_4392	COG1115	amino acid carrier protein
BF31_4394	COG2318	DinB family
BF31_4396	COG0776	regulation of translation
BF31_4399	COG2814	Major facilitator Superfamily
BF31_44	COG2329	Antibiotic biosynthesis monooxygenase
BF31_4400	COG3251	PFAM MbtH domain protein
BF31_4401	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF31_4402	COG3433	isochorismatase activity
BF31_4402	COG1535	isochorismatase
BF31_4403	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF31_4404	COG1169	isochorismate synthase
BF31_4405	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_4406	COG2223	nitrite transmembrane transporter activity
BF31_441	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF31_4410	COG0419	ATPase involved in DNA repair
BF31_4411	COG0420	3'-5' exonuclease activity
BF31_4414	COG1024	Enoyl-CoA hydratase
BF31_4415	COG1280	lysine exporter protein (LysE YggA)
BF31_4416	COG1012	belongs to the aldehyde dehydrogenase family
BF31_4417	COG2084	Dehydrogenase
BF31_4418	COG1960	acyl-CoA dehydrogenase activity
BF31_4419	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF31_442	COG1609	Transcriptional regulator
BF31_4420	COG2079	MmgE PrpD family protein
BF31_4421	COG0372	Belongs to the citrate synthase family
BF31_4422	COG4841	protein insertion into membrane
BF31_4423	COG2814	Major facilitator Superfamily
BF31_4424	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF31_4424	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF31_443	COG0477	Major facilitator Superfamily
BF31_4432	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF31_444	COG0477	Major facilitator Superfamily
BF31_4448	COG1715	Restriction endonuclease
BF31_4448	COG1787	Restriction endonuclease
BF31_445	COG1846	Transcriptional regulator
BF31_4453	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF31_4454	COG0671	phosphoesterase, PA-phosphatase related
BF31_4455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF31_4456	COG4326	sporulation control protein
BF31_446	COG2271	Major facilitator Superfamily
BF31_4464	COG1509	lysine 2,3-aminomutase activity
BF31_4465	COG3829	transcription factor binding
BF31_4466	COG0456	acetyltransferase
BF31_4467	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF31_4468	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF31_4469	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF31_4470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF31_4473	COG5506	Protein of unknown function (DUF1694)
BF31_4474	COG1012	belongs to the aldehyde dehydrogenase family
BF31_4475	COG1253	flavin adenine dinucleotide binding
BF31_448	COG4608	Belongs to the ABC transporter superfamily
BF31_4482	COG1174	glycine betaine transport
BF31_4483	COG0517	IMP dehydrogenase activity
BF31_4483	COG1125	glycine betaine transport
BF31_449	COG0601	transmembrane transport
BF31_4490	COG1070	Carbohydrate kinase
BF31_4497	COG1064	alcohol dehydrogenase
BF31_4498	COG1737	Transcriptional regulator
BF31_45	COG3428	Bacterial PH domain
BF31_4500	COG2197	response regulator
BF31_4501	COG4585	Histidine kinase
BF31_4501	COG2203	Gaf domain
BF31_4502	COG0668	transmembrane transport
BF31_4504	COG1051	belongs to the nudix hydrolase family
BF31_4505	COG1335	isochorismatase
BF31_4509	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF31_451	COG0747	negative chemotaxis
BF31_4510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_4514	COG0367	asparagine synthase
BF31_4515	COG0071	Belongs to the small heat shock protein (HSP20) family
BF31_4516	COG1999	signal sequence binding
BF31_4517	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF31_4518	COG1307	EDD domain protein, DegV family
BF31_4520	COG0805	protein transport
BF31_4522	COG1272	protein, Hemolysin III
BF31_4523	COG0204	Acyl-transferase
BF31_4524	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF31_4529	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF31_4533	COG0546	phosphoglycolate phosphatase activity
BF31_4535	COG4473	ABC transporter
BF31_4536	COG1131	(ABC) transporter
BF31_4538	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF31_454	COG0659	secondary active sulfate transmembrane transporter activity
BF31_4540	COG0456	acetyltransferase
BF31_4542	COG1794	racemase activity, acting on amino acids and derivatives
BF31_4543	COG1454	alcohol dehydrogenase
BF31_4544	COG2610	gluconate transmembrane transporter activity
BF31_4549	COG0733	neurotransmitter:sodium symporter activity
BF31_4552	COG5002	protein histidine kinase activity
BF31_4552	COG3850	Histidine kinase
BF31_4553	COG0745	RESPONSE REGULATOR receiver
BF31_4554	COG0471	metal ion transport
BF31_4555	COG1929	Belongs to the glycerate kinase type-1 family
BF31_457	COG5002	protein histidine kinase activity
BF31_4574	COG1674	ftsk spoiiie
BF31_4578	COG0017	Asparaginyl-tRNA synthetase
BF31_4579	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF31_458	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF31_4582	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF31_4588	COG0018	arginyl-trna synthetase
BF31_4589	COG2521	methyltransferase
BF31_4589	COG2136	Putative SAM-dependent methyltransferase
BF31_459	COG2378	regulation of single-species biofilm formation
BF31_4592	COG1413	lyase activity
BF31_4593	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF31_4596	COG0629	single-stranded DNA binding
BF31_4599	COG0488	(ABC) transporter
BF31_46	COG3402	PFAM membrane-flanked domain
BF31_4600	COG1418	mRNA catabolic process
BF31_4603	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF31_4606	COG2359	stage V sporulation protein S
BF31_4613	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF31_4614	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF31_4615	COG2146	nitrite reductase [NAD(P)H] activity
BF31_4616	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF31_4616	COG1587	Uroporphyrinogen-III synthase
BF31_4618	COG1648	precorrin-2 dehydrogenase activity
BF31_4621	COG2223	nitrite transmembrane transporter activity
BF31_4623	COG0314	molybdopterin synthase activity
BF31_4624	COG0303	'Molybdopterin
BF31_4625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF31_4626	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF31_4627	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF31_4631	COG2181	nitrate reductase activity
BF31_4632	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF31_4633	COG1140	nitrate reductase beta subunit
BF31_4634	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF31_4637	COG0714	Associated with various cellular activities
BF31_4638	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF31_4639	COG1305	Transglutaminase-like
BF31_464	COG0833	amino acid
BF31_4640	COG0386	Belongs to the glutathione peroxidase family
BF31_4645	COG1595	DNA-templated transcription, initiation
BF31_4646	COG0604	alcohol dehydrogenase
BF31_4648	COG0346	lactoylglutathione lyase activity
BF31_4649	COG1082	Xylose isomerase domain protein TIM barrel
BF31_465	COG0765	amino acid transport
BF31_4653	COG2226	methyltransferase
BF31_4658	COG3874	Sporulation protein YtfJ
BF31_466	COG0765	amino acid transport
BF31_4667	COG0456	acetyltransferase
BF31_467	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF31_4673	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_4674	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_4675	COG1819	glycosyl
BF31_4679	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF31_468	COG1126	abc transporter atp-binding protein
BF31_4681	COG0561	phosphatase activity
BF31_4685	COG2211	Major facilitator Superfamily
BF31_4686	COG0154	amidase activity
BF31_4688	COG1876	peptidase activity
BF31_469	COG1115	amino acid carrier protein
BF31_4690	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF31_4694	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF31_4695	COG1114	Component of the transport system for branched-chain amino acids
BF31_4698	COG1253	flavin adenine dinucleotide binding
BF31_4699	COG2839	Protein conserved in bacteria
BF31_470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF31_4700	COG0702	epimerase
BF31_4703	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF31_4704	COG1607	acyl-coa hydrolase
BF31_4705	COG3689	TIGRFAM TIGR03943 family protein
BF31_4706	COG0701	Predicted permease
BF31_4708	COG2244	polysaccharide biosynthetic process
BF31_4709	COG0586	Pfam SNARE associated Golgi protein
BF31_4710	COG1051	belongs to the nudix hydrolase family
BF31_4711	COG5337	Spore coat protein CotH
BF31_4713	COG0406	alpha-ribazole phosphatase activity
BF31_4716	COG4166	transmembrane transport
BF31_4718	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF31_472	COG0697	spore germination
BF31_4720	COG0702	epimerase
BF31_4722	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF31_4722	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF31_4733	COG0456	acetyltransferase
BF31_4734	COG0523	cobalamin synthesis protein
BF31_4735	COG4989	oxidoreductase activity
BF31_4737	COG1231	oxidoreductase activity
BF31_4739	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF31_4742	COG0783	Belongs to the Dps family
BF31_4743	COG3949	Membrane
BF31_4746	COG0840	transmembrane signaling receptor activity
BF31_4751	COG2814	Major facilitator Superfamily
BF31_4752	COG0667	Aldo Keto reductase
BF31_4753	COG0640	Transcriptional regulator
BF31_4754	COG1404	Belongs to the peptidase S8 family
BF31_4755	COG2002	toxin-antitoxin pair type II binding
BF31_4756	COG0577	efflux transmembrane transporter activity
BF31_4757	COG0577	efflux transmembrane transporter activity
BF31_476	COG0366	Alpha amylase catalytic
BF31_4764	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF31_4766	COG1279	arginine transmembrane transporter activity
BF31_4767	COG2814	Major facilitator Superfamily
BF31_4768	COG2814	Major facilitator Superfamily
BF31_477	COG1263	PTS System
BF31_477	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_4770	COG1082	Xylose isomerase domain protein TIM barrel
BF31_4773	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_4774	COG4264	IucA IucC family
BF31_4776	COG1247	-acetyltransferase
BF31_4777	COG1285	pathogenesis
BF31_4779	COG0726	polysaccharide deacetylase
BF31_478	COG2188	Transcriptional regulator
BF31_4780	COG5002	protein histidine kinase activity
BF31_4781	COG0745	RESPONSE REGULATOR receiver
BF31_4783	COG1316	TRANSCRIPTIONal
BF31_4788	COG0460	homoserine dehydrogenase
BF31_479	COG0531	amino acid
BF31_4792	COG0726	polysaccharide deacetylase
BF31_4794	COG0300	oxidoreductase activity
BF31_4796	COG5002	protein histidine kinase activity
BF31_4797	COG0745	RESPONSE REGULATOR receiver
BF31_4798	COG1132	(ABC) transporter
BF31_4799	COG1132	(ABC) transporter
BF31_4801	COG0791	NLP P60 protein
BF31_4801	COG1388	LysM domain
BF31_4803	COG1686	Belongs to the peptidase S11 family
BF31_4807	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF31_4808	COG4988	ABC transporter
BF31_4809	COG1294	oxidase, subunit
BF31_4810	COG1271	oxidase subunit
BF31_4812	COG1846	Transcriptional regulator
BF31_4816	COG0583	DNA-binding transcription factor activity
BF31_4820	COG0411	ABC transporter
BF31_4822	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_4823	COG2030	dehydratase
BF31_4824	COG0318	PFAM AMP-dependent synthetase and ligase
BF31_4827	COG0523	cobalamin synthesis protein
BF31_4828	COG1231	oxidoreductase activity
BF31_4829	COG0039	L-malate dehydrogenase activity
BF31_483	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF31_4830	COG0628	permease
BF31_4833	COG0778	Nitroreductase
BF31_4834	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF31_4835	COG1959	2 iron, 2 sulfur cluster binding
BF31_4836	COG0583	DNA-binding transcription factor activity
BF31_4837	COG0697	spore germination
BF31_4839	COG4549	nuclear export factor GLE1
BF31_484	COG0714	Associated with various cellular activities
BF31_4840	COG1276	copper resistance
BF31_4840	COG2372	response to copper ion
BF31_4842	COG1114	Component of the transport system for branched-chain amino acids
BF31_4843	COG1114	Component of the transport system for branched-chain amino acids
BF31_4844	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF31_485	COG4548	von Willebrand factor, type A
BF31_4850	COG2132	Multicopper oxidase
BF31_4851	COG2132	Multicopper oxidase
BF31_4852	COG0006	proline dipeptidase activity
BF31_4856	COG4224	UPF0291 protein
BF31_4858	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF31_4859	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_4861	COG2390	Transcriptional regulator
BF31_4866	COG0531	amino acid
BF31_4867	COG0531	amino acid
BF31_4869	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF31_487	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF31_4872	COG1914	H( )-stimulated, divalent metal cation uptake system
BF31_4877	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF31_488	COG0156	8-amino-7-oxononanoate synthase activity
BF31_4883	COG4166	transmembrane transport
BF31_4884	COG1073	alpha beta
BF31_4889	COG0427	acetyl-CoA hydrolase
BF31_489	COG2226	methyltransferase
BF31_4890	COG3279	Response regulator of the LytR AlgR family
BF31_4892	COG3384	dioxygenase
BF31_4893	COG2814	Major facilitator Superfamily
BF31_4898	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF31_4900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF31_4901	COG0440	acetolactate synthase activity
BF31_4902	COG0028	Belongs to the TPP enzyme family
BF31_4903	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF31_4905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF31_4909	COG2084	Dehydrogenase
BF31_491	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_4912	COG2323	membrane
BF31_4913	COG5566	PFAM Mor transcription activator
BF31_4915	COG0733	neurotransmitter:sodium symporter activity
BF31_4916	COG2244	polysaccharide biosynthetic process
BF31_4919	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF31_492	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_4920	COG2223	nitrite transmembrane transporter activity
BF31_4921	COG4166	transmembrane transport
BF31_4923	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF31_4925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_4926	COG0477	Major facilitator Superfamily
BF31_4927	COG0477	Major facilitator Superfamily
BF31_4929	COG1966	Carbon starvation protein
BF31_493	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_4934	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF31_4935	COG1051	belongs to the nudix hydrolase family
BF31_494	COG3104	oligopeptide transport
BF31_4946	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF31_4947	COG0784	Response regulator, receiver
BF31_4948	COG4191	Histidine kinase
BF31_4949	COG0281	malic enzyme
BF31_4950	COG1027	Aspartate ammonia-lyase
BF31_4952	COG0528	UMP kinase activity
BF31_4957	COG1131	(ABC) transporter
BF31_4964	COG2733	membrane
BF31_497	COG1620	l-lactate permease
BF31_4971	COG0785	Cytochrome C biogenesis protein
BF31_4975	COG3340	Belongs to the peptidase S51 family
BF31_4976	COG0534	Mate efflux family protein
BF31_4977	COG0534	Mate efflux family protein
BF31_498	COG1027	Aspartate ammonia-lyase
BF31_4981	COG0114	fumarate hydratase activity
BF31_4982	COG1757	Na H antiporter
BF31_4983	COG1216	Glycosyl transferase, family 2
BF31_4983	COG0438	transferase activity, transferring glycosyl groups
BF31_4985	COG0701	Predicted permease
BF31_4986	COG0523	cobalamin synthesis protein
BF31_4987	COG0697	spore germination
BF31_4988	COG1802	Transcriptional regulator
BF31_499	COG1253	flavin adenine dinucleotide binding
BF31_4994	COG0367	asparagine synthase
BF31_5	COG3708	Transcriptional regulator
BF31_5	COG2207	Transcriptional regulator
BF31_500	COG0346	lactoylglutathione lyase activity
BF31_5001	COG0406	alpha-ribazole phosphatase activity
BF31_5003	COG1686	Belongs to the peptidase S11 family
BF31_5008	COG1234	tRNA 3'-trailer cleavage
BF31_5009	COG1177	transmembrane transport
BF31_501	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_5010	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF31_5011	COG3842	ATPase activity
BF31_5017	COG2329	Antibiotic biosynthesis monooxygenase
BF31_502	COG1316	TRANSCRIPTIONal
BF31_5021	COG1309	transcriptional regulator
BF31_5026	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF31_5027	COG4786	Flagellar basal body rod
BF31_5028	COG1419	protein localization to endoplasmic reticulum
BF31_5029	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF31_503	COG2720	vancomycin resistance protein
BF31_5030	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF31_5032	COG1987	bacterial-type flagellum assembly
BF31_5033	COG1338	Plays a role in the flagellum-specific transport system
BF31_5035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF31_5035	COG1776	CheC inhibitor of MCP methylation
BF31_5037	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF31_5038	COG0741	lytic transglycosylase activity
BF31_5039	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF31_5044	COG0457	Tetratricopeptide repeat
BF31_5044	COG0463	Glycosyl transferase, family 2
BF31_5050	COG0463	Glycosyl transferase, family 2
BF31_5052	COG0784	Response regulator, receiver
BF31_5052	COG0835	chemotaxis
BF31_5061	COG1157	protein secretion by the type III secretion system
BF31_5063	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF31_5065	COG1766	The M ring may be actively involved in energy transduction
BF31_5066	COG1677	Flagellar hook-basal body complex protein FliE
BF31_5067	COG1558	bacterial-type flagellum-dependent cell motility
BF31_5068	COG1815	bacterial-type flagellum-dependent cell motility
BF31_507	COG3227	Zinc metalloprotease (Elastase)
BF31_5073	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF31_5079	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF31_5082	COG1776	CheC inhibitor of MCP methylation
BF31_5082	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF31_5083	COG0643	Histidine kinase
BF31_5083	COG2198	Histidine kinase
BF31_5084	COG0643	Histidine kinase
BF31_5084	COG2198	Histidine kinase
BF31_5085	COG2201	protein-glutamate methylesterase activity
BF31_5086	COG1360	Flagellar Motor Protein
BF31_5087	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF31_5089	COG1923	regulation of RNA biosynthetic process
BF31_510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF31_5100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF31_5101	COG2323	membrane
BF31_5103	COG0789	Transcriptional regulator
BF31_5103	COG4978	Transcriptional regulator
BF31_5104	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF31_5105	COG0475	glutathione-regulated potassium exporter activity
BF31_5107	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF31_5108	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF31_5109	COG3162	membrane
BF31_511	COG2217	Heavy metal translocating P-type atpase
BF31_5112	COG1280	lysine exporter protein (LysE YggA)
BF31_512	COG0640	Transcriptional regulator
BF31_5120	COG0328	RNA-DNA hybrid ribonuclease activity
BF31_5124	COG0454	-acetyltransferase
BF31_5127	COG0438	transferase activity, transferring glycosyl groups
BF31_5128	COG1215	transferase activity, transferring glycosyl groups
BF31_513	COG0531	amino acid
BF31_5131	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF31_5138	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF31_5141	COG0754	glutathionylspermidine amidase activity
BF31_5146	COG0456	acetyltransferase
BF31_5148	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF31_5150	COG2311	Membrane
BF31_5151	COG2233	PERMEase
BF31_5153	COG0024	Methionine aminopeptidase
BF31_5154	COG3173	Aminoglycoside phosphotransferase
BF31_5156	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF31_5157	COG1199	ATP-dependent helicase activity
BF31_5159	COG0116	Belongs to the methyltransferase superfamily
BF31_5161	COG4474	Belongs to the UPF0398 family
BF31_5170	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF31_5170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF31_5172	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF31_5173	COG3935	DnaD domain protein
BF31_5177	COG1199	ATP-dependent helicase activity
BF31_5177	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF31_518	COG3383	formate dehydrogenase (NAD+) activity
BF31_5184	COG0438	transferase activity, transferring glycosyl groups
BF31_5185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF31_5188	COG1694	Mazg nucleotide pyrophosphohydrolase
BF31_5189	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_519	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF31_5191	COG2738	Putative neutral zinc metallopeptidase
BF31_5194	COG4347	Protein of unknown function (DUF1405)
BF31_5196	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF31_520	COG0454	-acetyltransferase
BF31_520	COG0456	acetyltransferase
BF31_5200	COG0457	Tetratricopeptide repeat
BF31_5201	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF31_5204	COG0105	UTP biosynthetic process
BF31_5205	COG0142	geranyltranstransferase activity
BF31_5207	COG0142	geranyltranstransferase activity
BF31_5210	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF31_522	COG0745	RESPONSE REGULATOR receiver
BF31_5224	COG0252	asparaginase activity
BF31_5225	COG0492	ferredoxin-NADP+ reductase activity
BF31_5229	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF31_5230	COG4862	establishment of competence for transformation
BF31_5232	COG1408	metallophosphoesterase
BF31_5234	COG1266	CAAX protease self-immunity
BF31_5235	COG0514	ATP-dependent DNA helicase (RecQ)
BF31_5236	COG4955	Helix-turn-helix domain
BF31_5237	COG1141	Ferredoxin
BF31_5238	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF31_5241	COG2096	Adenosyltransferase
BF31_5242	COG5002	protein histidine kinase activity
BF31_5243	COG0745	RESPONSE REGULATOR receiver
BF31_5244	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF31_5245	COG1333	cytochrome c biogenesis protein
BF31_5247	COG1187	pseudouridine synthase activity
BF31_5248	COG0700	Nucleoside recognition
BF31_5249	COG2715	membrane protein required for spore maturation
BF31_5250	COG1686	Belongs to the peptidase S11 family
BF31_5251	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF31_5254	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF31_5254	COG0392	lysyltransferase activity
BF31_5258	COG5002	protein histidine kinase activity
BF31_5259	COG0582	viral genome integration into host DNA
BF31_526	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF31_5261	COG1801	Protein of unknown function DUF72
BF31_5262	COG3852	Histidine kinase
BF31_5265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF31_5266	COG1392	Phosphate transport regulator
BF31_5267	COG0306	phosphate transporter
BF31_5268	COG0730	response to heat
BF31_5271	COG1017	nitric oxide dioxygenase activity
BF31_5271	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF31_5276	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF31_5278	COG1114	Component of the transport system for branched-chain amino acids
BF31_5280	COG2197	response regulator
BF31_5281	COG4585	Histidine kinase
BF31_5282	COG4758	membrane
BF31_5285	COG1757	Na H antiporter
BF31_5289	COG0733	neurotransmitter:sodium symporter activity
BF31_529	COG0281	malic enzyme
BF31_5290	COG1648	precorrin-2 dehydrogenase activity
BF31_5294	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF31_5295	COG0529	Catalyzes the synthesis of activated sulfate
BF31_5299	COG0019	diaminopimelate decarboxylase activity
BF31_530	COG3493	citrate carrier protein
BF31_5301	COG1368	sulfuric ester hydrolase activity
BF31_5302	COG1183	phosphatidylcholine synthase activity
BF31_5305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF31_531	COG4565	transcriptional regulatory protein
BF31_5312	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF31_5317	COG0473	3-isopropylmalate dehydrogenase activity
BF31_5319	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF31_532	COG3290	protein histidine kinase activity
BF31_5320	COG0440	acetolactate synthase activity
BF31_5321	COG0028	Belongs to the TPP enzyme family
BF31_5322	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF31_5327	COG3874	Sporulation protein YtfJ
BF31_5328	COG4709	membrane
BF31_5329	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF31_5330	COG1301	dicarboxylic acid transport
BF31_5332	COG1846	Transcriptional regulator
BF31_5335	COG1968	undecaprenyl-diphosphatase activity
BF31_5336	COG0534	Mate efflux family protein
BF31_534	COG4990	cell redox homeostasis
BF31_5340	COG3173	Aminoglycoside phosphotransferase
BF31_5343	COG0716	FMN binding
BF31_5348	COG1696	Membrane protein involved in D-alanine export
BF31_5350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF31_5351	COG2070	2-Nitropropane dioxygenase
BF31_5352	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF31_5354	COG1335	isochorismatase
BF31_5356	COG1522	sequence-specific DNA binding
BF31_5359	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF31_536	COG5002	protein histidine kinase activity
BF31_5360	COG1131	(ABC) transporter
BF31_5362	COG1131	(ABC) transporter
BF31_5363	COG1725	Transcriptional regulator
BF31_5364	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF31_5365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF31_5367	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF31_5368	COG1780	Probably involved in ribonucleotide reductase function
BF31_537	COG0745	RESPONSE REGULATOR receiver
BF31_5375	COG4873	Protein conserved in bacteria
BF31_5378	COG0720	synthase
BF31_538	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF31_5380	COG5002	protein histidine kinase activity
BF31_5382	COG2318	DinB family
BF31_5384	COG1846	Transcriptional regulator
BF31_5385	COG3852	Histidine kinase
BF31_5387	COG2861	carbohydrate metabolic process
BF31_5390	COG0235	Class ii aldolase
BF31_5395	COG1349	DNA-binding transcription factor activity
BF31_5398	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF31_540	COG0395	ABC-type sugar transport system, permease component
BF31_5401	COG3842	ATPase activity
BF31_5402	COG3842	ATPase activity
BF31_5404	COG1840	ABC-type Fe3 transport system, periplasmic component
BF31_5407	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF31_5409	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF31_541	COG1175	transmembrane transport
BF31_5410	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_5414	COG2030	dehydratase
BF31_5418	COG0861	Integral membrane protein TerC family
BF31_5419	COG2116	formate transmembrane transporter activity
BF31_542	COG3842	ATPase activity
BF31_5421	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF31_5425	COG2186	Transcriptional regulator
BF31_5426	COG5002	protein histidine kinase activity
BF31_5427	COG0745	RESPONSE REGULATOR receiver
BF31_5429	COG3835	regulator
BF31_543	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF31_5430	COG0277	FAD linked oxidase domain protein
BF31_5431	COG0247	lactate metabolic process
BF31_5432	COG2340	Cysteine-rich secretory protein family
BF31_5434	COG0564	pseudouridine synthase activity
BF31_5436	COG2409	Drug exporters of the RND superfamily
BF31_5438	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF31_5439	COG1177	transmembrane transport
BF31_5440	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF31_5441	COG3842	ATPase activity
BF31_5442	COG1012	belongs to the aldehyde dehydrogenase family
BF31_5448	COG0681	Belongs to the peptidase S26 family
BF31_5449	COG1686	Belongs to the peptidase S11 family
BF31_5451	COG2226	methyltransferase
BF31_5462	COG1476	TRANSCRIPTIONal
BF31_5464	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF31_547	COG2851	Citrate transporter
BF31_5474	COG5634	Uncharacterized conserved protein (DUF2278)
BF31_5475	COG1620	l-lactate permease
BF31_548	COG4565	transcriptional regulatory protein
BF31_5482	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF31_5482	COG0512	Glutamine amidotransferase of anthranilate synthase
BF31_5484	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF31_5485	COG5492	domain, Protein
BF31_5488	COG2382	esterase
BF31_5489	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF31_549	COG3290	protein histidine kinase activity
BF31_5490	COG2153	protein acetylation
BF31_5498	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF31_5501	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF31_5505	COG0457	Tetratricopeptide repeat
BF31_5505	COG0463	Glycosyl transferase, family 2
BF31_5509	COG1216	Glycosyl transferase, family 2
BF31_551	COG2268	Band 7 protein
BF31_5510	COG0772	Belongs to the SEDS family
BF31_5511	COG0772	Belongs to the SEDS family
BF31_5514	COG0564	pseudouridine synthase activity
BF31_5515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF31_5516	COG2357	RelA SpoT domain protein
BF31_5518	COG4116	CYTH
BF31_5519	COG2346	COG2346, Truncated hemoglobins
BF31_552	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF31_5522	COG1164	Oligoendopeptidase f
BF31_5524	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF31_5525	COG4862	establishment of competence for transformation
BF31_5526	COG0861	Integral membrane protein TerC family
BF31_5527	COG1393	Belongs to the ArsC family
BF31_5529	COG4166	transmembrane transport
BF31_5530	COG0534	Mate efflux family protein
BF31_5531	COG4608	Belongs to the ABC transporter superfamily
BF31_5532	COG0444	Belongs to the ABC transporter superfamily
BF31_5533	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF31_5534	COG0601	transmembrane transport
BF31_5535	COG4166	transmembrane transport
BF31_5537	COG0180	Tryptophanyl-tRNA synthetase
BF31_5539	COG5504	Zn-dependent protease
BF31_554	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF31_5540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF31_5541	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF31_5544	COG2267	carboxylic ester hydrolase activity
BF31_5546	COG0542	response to heat
BF31_5548	COG0561	phosphatase activity
BF31_5551	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_5553	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF31_5555	COG2996	Protein conserved in bacteria
BF31_5559	COG0004	ammonium transporteR
BF31_5560	COG0753	catalase activity
BF31_5562	COG0367	asparagine synthase
BF31_5576	COG1074	ATP-dependent DNA helicase activity
BF31_5577	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF31_5579	COG0398	Pfam SNARE associated Golgi protein
BF31_558	COG2766	serine protein kinase
BF31_5580	COG4903	ComK protein
BF31_5583	COG1278	Cold shock
BF31_5585	COG2224	Isocitrate lyase
BF31_5586	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF31_5587	COG0497	DNA recombination
BF31_5590	COG0697	spore germination
BF31_5591	COG0840	transmembrane signaling receptor activity
BF31_5592	COG0501	Belongs to the peptidase M48B family
BF31_56	COG3428	Bacterial PH domain
BF31_561	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF31_5628	COG3344	reverse transcriptase
BF31_563	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF31_565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF31_5650	COG3344	reverse transcriptase
BF31_566	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF31_5671	COG1923	regulation of RNA biosynthetic process
BF31_5673	COG0457	Tetratricopeptide repeat
BF31_5678	COG4974	Belongs to the 'phage' integrase family
BF31_5680	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF31_5682	COG2801	Transposase and inactivated derivatives
BF31_5684	COG2801	Transposase and inactivated derivatives
BF31_5687	COG2801	Transposase and inactivated derivatives
BF31_5696	COG4974	Belongs to the 'phage' integrase family
BF31_5698	COG2002	toxin-antitoxin pair type II binding
BF31_5733	COG2801	Transposase and inactivated derivatives
BF31_5734	COG2801	Transposase and inactivated derivatives
BF31_5738	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF31_5739	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF31_5743	COG0671	phosphoesterase, PA-phosphatase related
BF31_5744	COG4196	transglutaminase domain protein
BF31_5750	COG2311	Membrane
BF31_5780	COG4962	Type ii secretion system protein e
BF31_5796	COG4166	transmembrane transport
BF31_5799	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF31_58	COG3402	PFAM membrane-flanked domain
BF31_5809	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF31_5810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF31_5824	COG0741	lytic transglycosylase activity
BF31_5824	COG0791	NLP P60 protein
BF31_5858	COG1192	Involved in chromosome partitioning
BF31_5863	COG2801	Transposase and inactivated derivatives
BF31_5869	COG1683	Conserved Protein
BF31_5870	COG1309	transcriptional regulator
BF31_5887	COG0681	Belongs to the peptidase S26 family
BF31_5895	COG1280	lysine exporter protein (LysE YggA)
BF31_591	COG0735	belongs to the Fur family
BF31_592	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF31_596	COG4555	ABC transporter
BF31_598	COG0067	glutamate synthase
BF31_598	COG0069	glutamate synthase activity
BF31_598	COG0070	glutamate synthase
BF31_599	COG4129	membrane
BF31_6	COG1595	DNA-templated transcription, initiation
BF31_60	COG1309	transcriptional regulator
BF31_600	COG1132	(ABC) transporter
BF31_605	COG1194	a g-specific adenine glycosylase
BF31_606	COG1988	membrane-bound metal-dependent
BF31_612	COG1090	epimerase
BF31_613	COG1228	amidohydrolase
BF31_617	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF31_620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF31_620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF31_623	COG0463	Glycosyl transferase, family 2
BF31_626	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF31_627	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_627	COG1263	PTS System
BF31_628	COG2066	Belongs to the glutaminase family
BF31_63	COG4473	ABC transporter
BF31_633	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF31_634	COG0833	amino acid
BF31_636	COG3829	transcription factor binding
BF31_638	COG0101	tRNA pseudouridine synthase activity
BF31_64	COG1131	(ABC) transporter
BF31_65	COG0537	adenosine 5'-monophosphoramidase activity
BF31_66	COG4980	gas vesicle protein
BF31_685	COG1484	DNA-dependent DNA replication
BF31_692	COG1396	sequence-specific DNA binding
BF31_696	COG0582	viral genome integration into host DNA
BF31_697	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF31_698	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF31_70	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF31_703	COG0535	radical SAM domain protein
BF31_705	COG0387	Pfam Sodium calcium exchanger
BF31_706	COG3871	stress protein (general stress protein 26)
BF31_709	COG0586	Pfam SNARE associated Golgi protein
BF31_71	COG3973	AAA domain
BF31_712	COG0681	Belongs to the peptidase S26 family
BF31_714	COG0697	spore germination
BF31_715	COG2217	Heavy metal translocating P-type atpase
BF31_716	COG1295	ribonuclease BN
BF31_718	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF31_721	COG3853	Toxic anion resistance protein (TelA)
BF31_723	COG0861	Integral membrane protein TerC family
BF31_724	COG2310	stress, protein
BF31_725	COG2310	stress, protein
BF31_726	COG2310	stress, protein
BF31_729	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF31_73	COG0477	Major facilitator Superfamily
BF31_732	COG2270	Major facilitator Superfamily
BF31_74	COG0477	Major facilitator Superfamily
BF31_741	COG0488	(ABC) transporter
BF31_742	COG1116	anion transmembrane transporter activity
BF31_744	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF31_747	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF31_753	COG1263	PTS System
BF31_753	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF31_753	COG2190	(PTS) system
BF31_754	COG0366	Alpha amylase catalytic
BF31_755	COG0840	transmembrane signaling receptor activity
BF31_756	COG0840	transmembrane signaling receptor activity
BF31_758	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF31_759	COG0765	amino acid transport
BF31_761	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF31_761	COG0723	plastoquinol--plastocyanin reductase activity
BF31_762	COG2814	Major facilitator Superfamily
BF31_763	COG3541	Predicted nucleotidyltransferase
BF31_767	COG5002	protein histidine kinase activity
BF31_773	COG0166	Belongs to the GPI family
BF31_776	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF31_777	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_778	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF31_779	COG0235	Class ii aldolase
BF31_781	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF31_782	COG0450	alkyl hydroperoxide reductase
BF31_785	COG1473	amidohydrolase
BF31_791	COG4807	Protein conserved in bacteria
BF31_793	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF31_794	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF31_795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF31_798	COG2309	aminopeptidase activity
BF31_799	COG2076	Multidrug Resistance protein
BF31_8	COG1078	dGTPase activity
BF31_800	COG1012	belongs to the aldehyde dehydrogenase family
BF31_802	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF31_803	COG0546	phosphoglycolate phosphatase activity
BF31_804	COG1597	lipid kinase activity
BF31_808	COG4682	membrane
BF31_809	COG1846	Transcriptional regulator
BF31_810	COG0003	Pfam Anion-transporting ATPase
BF31_811	COG0003	Pfam Anion-transporting ATPase
BF31_814	COG1464	Belongs to the NlpA lipoprotein family
BF31_815	COG2011	ABC-type metal ion transport system permease component
BF31_816	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF31_817	COG1335	isochorismatase
BF31_82	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF31_821	COG4851	CamS sex pheromone cAM373 precursor
BF31_829	COG0151	Belongs to the GarS family
BF31_831	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF31_833	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF31_836	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF31_838	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF31_839	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF31_84	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF31_840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF31_845	COG0745	RESPONSE REGULATOR receiver
BF31_846	COG2205	protein histidine kinase activity
BF31_849	COG1968	undecaprenyl-diphosphatase activity
BF31_85	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF31_855	COG1215	transferase activity, transferring glycosyl groups
BF31_861	COG2226	methyltransferase
BF31_869	COG5002	protein histidine kinase activity
BF31_871	COG2252	PERMEase
BF31_875	COG1266	CAAX protease self-immunity
BF31_878	COG0488	(ABC) transporter
BF31_879	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF31_880	COG0456	acetyltransferase
BF31_881	COG1214	PFAM Peptidase M22, glycoprotease
BF31_882	COG0802	atpase or kinase
BF31_89	COG2267	carboxylic ester hydrolase activity
BF31_9	COG1408	metallophosphoesterase
BF31_901	COG2183	response to ionizing radiation
BF31_902	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF31_903	COG0864	Transcriptional regulator
BF31_904	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF31_905	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF31_907	COG4294	response to UV
BF31_908	COG0457	Tetratricopeptide repeat
BF31_908	COG0705	Rhomboid family
BF31_91	COG0457	Tetratricopeptide repeat
BF31_910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF31_913	COG2814	Major facilitator Superfamily
BF31_915	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF31_916	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF31_92	COG0346	lactoylglutathione lyase activity
BF31_922	COG0561	phosphatase activity
BF31_923	COG0561	phosphatase activity
BF31_924	COG4608	Belongs to the ABC transporter superfamily
BF31_925	COG0444	Belongs to the ABC transporter superfamily
BF31_927	COG0601	transmembrane transport
BF31_928	COG0747	negative chemotaxis
BF31_93	COG0346	lactoylglutathione lyase activity
BF31_931	COG0488	(ABC) transporter
BF31_935	COG5298	Protein conserved in bacteria
BF31_936	COG0084	hydrolase, TatD family'
BF31_939	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF31_94	COG2814	Major facilitator Superfamily
BF31_941	COG1609	Transcriptional regulator
BF31_943	COG0204	Acyl-transferase
BF31_946	COG0697	spore germination
BF31_947	COG0583	DNA-binding transcription factor activity
BF31_95	COG1309	transcriptional regulator
BF31_950	COG1910	domain protein
BF31_951	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF31_952	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF31_953	COG4149	molybdate abc transporter
BF31_956	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF31_957	COG0656	L-ascorbic acid biosynthetic process
BF31_958	COG4166	transmembrane transport
BF31_959	COG4166	transmembrane transport
BF31_962	COG2207	Transcriptional regulator
BF31_964	COG4166	transmembrane transport
BF31_965	COG4608	Belongs to the ABC transporter superfamily
BF31_966	COG0444	Belongs to the ABC transporter superfamily
BF31_967	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF31_968	COG0601	transmembrane transport
BF31_971	COG2814	Major facilitator Superfamily
BF31_973	COG2271	Major facilitator Superfamily
BF31_974	COG0277	FAD linked oxidase domain protein
BF31_977	COG1464	Belongs to the NlpA lipoprotein family
BF31_978	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF31_979	COG2011	ABC-type metal ion transport system permease component
BF31_980	COG1028	Short-chain dehydrogenase reductase Sdr
BF31_988	COG1506	peptidase
BF31_988	COG0823	Involved in the tonB-independent uptake of proteins
BF31_988	COG4946	Tricorn protease homolog
BF31_989	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF31_99	COG4717	serine-type aminopeptidase activity
BF31_994	COG0596	Alpha beta hydrolase
BF31_995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF31_997	COG4856	YbbR-like protein
BF31_998	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria