locus-tag class description BASH2_00001 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BASH2_00003 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BASH2_00004 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BASH2_00006 ENOG4107ZXI Rhomboid family BASH2_00009 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BASH2_00010 ENOG4105CPF Cell wall formation (By similarity) BASH2_00011 ENOG4105CPF Cell wall formation (By similarity) BASH2_00012 ENOG4108SC4 )-transporter BASH2_00014 ENOG4105ERH Fumarylacetoacetate hydrolase BASH2_00015 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BASH2_00020 ENOG410667J hydrolase BASH2_00021 ENOG4108JQ7 (ABC) transporter BASH2_00022 ENOG4105C3U ABC transporter BASH2_00023 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BASH2_00025 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BASH2_00027 ENOG4105C5H ABC transporter BASH2_00032 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BASH2_00033 ENOG4108RE7 deoxyribonuclease BASH2_00036 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BASH2_00039 ENOG4105F6E Acyl-transferase BASH2_00046 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BASH2_00048 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BASH2_00049 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BASH2_00050 ENOG4105E0C molybdate abc transporter BASH2_00053 ENOG4107XDY Nicotinamide Mononucleotide Transporter BASH2_00054 ENOG4105II7 pyrroline-5-carboxylate reductase BASH2_00056 ENOG4108J59 Extracellular solute-binding protein, family 5 BASH2_00057 ENOG4108J59 Extracellular solute-binding protein, family 5 BASH2_00062 ENOG4108JQ7 (ABC) transporter BASH2_00063 ENOG4105C3U ABC transporter BASH2_00064 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BASH2_00065 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BASH2_00068 ENOG4105C2C drug resistance transporter, Bcr CflA BASH2_00071 ENOG4105IQ5 FAD linked oxidase domain protein BASH2_00073 ENOG4105EE1 crotonyl-CoA reductase BASH2_00074 ENOG4105D01 (LipO)protein BASH2_00075 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BASH2_00076 ENOG4108UMI ABC transporter, permease BASH2_00077 ENOG4108PSK reductase BASH2_00085 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BASH2_00086 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BASH2_00088 ENOG4105CMG Carbohydrate kinase BASH2_00089 ENOG4105CMG Carbohydrate kinase BASH2_00091 ENOG4108VQT Alpha beta hydrolase fold protein BASH2_00092 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BASH2_00094 ENOG4107U5W ybbr family BASH2_00095 ENOG4105C8B TIGR00159 family BASH2_00101 ENOG4108NMV polysaccharide deacetylase BASH2_00104 ENOG4105D1F ATP-binding protein BASH2_00109 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BASH2_00110 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BASH2_00111 ENOG4108JJB ABC transporter BASH2_00117 ENOG41067V7 50S ribosomal protein L36 BASH2_00119 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BASH2_00121 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BASH2_00126 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BASH2_00147 ENOG4105XPM ribosomal protein BASH2_00148 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BASH2_00150 ENOG4107Y49 methyltransferase BASH2_00155 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BASH2_00157 ENOG4105QIV RNA polymerase BASH2_00158 ENOG4105M0M Tetracycline resistance protein BASH2_00159 ENOG4105C2N RNA methyltransferase TrmH family group 3 BASH2_00162 ENOG4105D7W serine acetyltransferase BASH2_00166 ENOG4105CTP PilT protein domain protein BASH2_00168 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BASH2_00171 ENOG4108Z0C Uvrb UvrC protein BASH2_00175 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BASH2_00177 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BASH2_00178 ENOG4105KRF dihydroneopterin aldolase BASH2_00179 ENOG4105EEI dihydropteroate synthase BASH2_00180 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BASH2_00181 ENOG4105DDQ anthranilate synthase BASH2_00182 ENOG4105CRQ synthase (Component I) BASH2_00183 ENOG4105C6T cysteine synthase BASH2_00186 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BASH2_00187 ENOG4108UGV hypoxanthine phosphoribosyltransferase BASH2_00188 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BASH2_00190 ENOG41060GV RNA binding s1 domain protein BASH2_00193 ENOG4105VYY sporulation protein yabp BASH2_00194 ENOG41082I2 s4 domain protein BASH2_00195 ENOG4108IY2 MazG family BASH2_00197 ENOG4108M14 stage v sporulation protein t BASH2_00198 ENOG4108JA2 transcriptioN-repair coupling factor BASH2_00200 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BASH2_00201 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BASH2_00204 ENOG4105KME endoribonuclease L-psp BASH2_00205 ENOG4105DFT pur operon repressor BASH2_00208 ENOG4105W42 Veg protein BASH2_00209 ENOG4105XFA sporulation peptidase YabG BASH2_00211 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BASH2_00212 ENOG4105F8V Hydrolase, tatD family BASH2_00214 ENOG4105KRN Transcriptional regulator, abrb family BASH2_00215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BASH2_00217 ENOG41060K3 Methyltransferase BASH2_00219 ENOG4105MA4 psp1 domain protein BASH2_00220 ENOG4105FA2 dna polymerase iii BASH2_00222 ENOG4105CXN decarboxylase BASH2_00225 ENOG41067KS pro-sigma K processing BASH2_00229 ENOG4105C6E dna polymerase iii BASH2_00230 ENOG4108Z6B deaminase BASH2_00231 ENOG4105GTG Isochorismatase BASH2_00233 ENOG4105ZMH deoxynucleoside kinase BASH2_00239 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BASH2_00242 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BASH2_00245 ENOG410848D S4 domain protein YaaA BASH2_00246 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BASH2_00250 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BASH2_00252 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BASH2_00256 ENOG4107QJE Chromosome Partitioning Protein BASH2_00257 ENOG4105FA0 parb-like partition protein BASH2_00258 ENOG4108ZDA Sporulation protein YyaC BASH2_00259 ENOG4105D8X mechanosensitive ion channel BASH2_00260 ENOG4105VDK protein, conserved in bacteria BASH2_00261 ENOG4105C3G gtp-binding protein BASH2_00263 ENOG4108UUM single-stranded DNA-binding protein BASH2_00265 ENOG4108XMW Membrane BASH2_00266 ENOG4105BZR domain protein BASH2_00268 ENOG4105CDU Replicative dna helicase BASH2_00270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_00271 ENOG4105BZU Histidine kinase BASH2_00274 ENOG4105Q2H domain protein BASH2_00275 ENOG4105C0H protease BASH2_00280 ENOG4105DPN Oligoendopeptidase f BASH2_00283 ENOG4105C1J atp-dependent rna helicase BASH2_00285 ENOG4108UT2 hemolysin iii BASH2_00286 ENOG4105CMR udp-glucose 4-epimerase BASH2_00288 ENOG4105IW1 AmiS UreI transporter BASH2_00290 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BASH2_00293 ENOG4107RGD Major Facilitator superfamily BASH2_00294 ENOG4108HRK Histidine kinase BASH2_00295 ENOG4105DY9 regulatoR BASH2_00299 ENOG4106F5Q Membrane BASH2_00301 ENOG4105E0X reductase BASH2_00303 ENOG41067SE Tetr family transcriptional regulator BASH2_00304 ENOG4105CKK Glycosyl transferase, family 2 BASH2_00309 ENOG4105C5H ABC transporter BASH2_00310 ENOG4105JEU Glycosyl transferase, family 2 BASH2_00312 ENOG4108S4H thioesterase Superfamily protein BASH2_00314 ENOG4106YBV Methyl-accepting chemotaxis BASH2_00315 ENOG4105EN6 Membrane BASH2_00320 ENOG41079KZ Major Facilitator Superfamily BASH2_00321 ENOG4105DY9 regulatoR BASH2_00322 ENOG4105D22 carbon starvation protein BASH2_00323 ENOG4105VCD cytoplasmic protein BASH2_00324 ENOG4105BZU Histidine kinase BASH2_00325 ENOG4105DWF phosphomethylpyrimidine kinase BASH2_00326 ENOG4105BZU Histidine kinase BASH2_00327 ENOG4105BZU Histidine kinase BASH2_00328 ENOG4105WH1 Two component transcriptional regulator luxr family BASH2_00330 ENOG4108Y4K DNA-binding transcriptional activator BASH2_00335 ENOG4105D6E homoserine dehydrogenase BASH2_00338 ENOG41090WU lipolytic protein G-D-S-L family BASH2_00339 ENOG4105CJ1 ABC, transporter BASH2_00340 ENOG4108TU7 Inherit from COG: (ABC) transporter BASH2_00342 ENOG4105VCH membrane BASH2_00343 ENOG410667J hydrolase BASH2_00345 ENOG4107SVH Potassium channel protein BASH2_00346 ENOG4105NCW Trka-c domain protein BASH2_00350 ENOG4108VKI Cell wall hydrolase BASH2_00354 ENOG4108IJ2 phosphate acetyltransferase BASH2_00357 ENOG4108VCI transcription factor, rsfa family BASH2_00359 ENOG4105DQ5 transport system permease protein BASH2_00360 ENOG4105DQ5 transport system permease protein BASH2_00361 ENOG4105EHG Permease protein BASH2_00362 ENOG4105E0A ABC, transporter BASH2_00363 ENOG4108MES Periplasmic binding protein BASH2_00364 ENOG4105DCI Phosphohydrolase BASH2_00365 ENOG41069HH 4-oxalocrotonate tautomerase BASH2_00367 ENOG4108Z4T Peptidase M50 BASH2_00368 ENOG4108XFG YwhD family BASH2_00369 ENOG4105BZ4 penicillin-binding protein BASH2_00370 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BASH2_00371 ENOG4107SWG transcriptional regulator MERR family BASH2_00372 ENOG4105DXB Major Facilitator superfamily BASH2_00374 ENOG4105CYW agmatinase BASH2_00379 ENOG410684U Domain of unknown function (DUF1934) BASH2_00381 ENOG4105EMN RNA polymerase sigma factor BASH2_00385 ENOG4105IIU Aminopeptidase BASH2_00390 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BASH2_00391 ENOG4108M15 ABC transporter BASH2_00392 ENOG4105KCT ABC transporter BASH2_00393 ENOG4105BZU Histidine kinase BASH2_00398 ENOG4105BZU Histidine kinase BASH2_00401 ENOG4105DF6 Fe-S oxidoreductase BASH2_00404 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BASH2_00405 ENOG4105C1G acyl-Coa dehydrogenase BASH2_00406 ENOG4105C1G acyl-Coa dehydrogenase BASH2_00413 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BASH2_00414 ENOG4105CBT Fructose-1,6-bisphosphatase BASH2_00415 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BASH2_00417 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BASH2_00418 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BASH2_00419 ENOG4108ZXQ stage ii sporulation protein r BASH2_00421 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BASH2_00424 ENOG4107XC4 flavin reductase domain protein, FMN-binding BASH2_00425 ENOG4108VGI doxx family BASH2_00428 ENOG4108YZG isomerase BASH2_00434 ENOG41062M3 atp synthase BASH2_00435 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BASH2_00445 ENOG4105BZU Histidine kinase BASH2_00446 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BASH2_00448 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BASH2_00449 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BASH2_00454 ENOG4105D65 subunit l BASH2_00455 ENOG4105C8S subunit m BASH2_00456 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BASH2_00457 ENOG4106778 Protein of unknown function (DUF1146) BASH2_00461 ENOG4108IUW ABC transporter BASH2_00462 ENOG4105DY9 regulatoR BASH2_00465 ENOG4105FRN stage II sporulation protein BASH2_00468 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BASH2_00480 ENOG4105EY8 ABC transporter BASH2_00481 ENOG4105EY8 ABC transporter BASH2_00482 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BASH2_00485 ENOG4105CMR udp-glucose 4-epimerase BASH2_00486 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_00487 ENOG4105BZU Histidine kinase BASH2_00490 ENOG4105CXY transporter BASH2_00493 ENOG4105C19 ABC transporter BASH2_00494 ENOG4107RBB ABC transporter, permease BASH2_00496 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_00503 ENOG4105C0D helicase BASH2_00504 ENOG4105KBK Zinc finger, swim domain protein BASH2_00509 ENOG41069ER domain protein BASH2_00510 ENOG4105C94 Transporter BASH2_00512 ENOG4107R8N Glycosyl transferase, family 2 BASH2_00515 ENOG4105D9N nucleoside BASH2_00520 ENOG4105E0M Sulfatase BASH2_00522 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BASH2_00524 ENOG4105DAA L-lactate BASH2_00534 ENOG4107RSM transcriptional regulator BASH2_00535 ENOG4105ECB domain protein BASH2_00536 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_00539 ENOG4105VZJ PTS System BASH2_00541 ENOG4105VCP PTS System BASH2_00542 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BASH2_00543 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BASH2_00545 ENOG4105CK1 PTS System BASH2_00546 ENOG4105VCP PTS System BASH2_00547 ENOG4105F8D glycoside hydrolase family 4 BASH2_00548 ENOG410901P UPF0249 protein BASH2_00551 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BASH2_00553 ENOG4105ESV Glycosyl transferase, family 4 BASH2_00554 ENOG4105C6Y Udp-glucose 6-dehydrogenase BASH2_00555 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BASH2_00556 ENOG4108KGH TRANSCRIPTIONal BASH2_00557 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BASH2_00560 ENOG4105KVH Transcriptional regulator BASH2_00563 ENOG41081UC Inherit from COG: Competence protein BASH2_00564 ENOG4105VEQ Cold shock protein BASH2_00565 ENOG4105MS2 ribosomal subunit Interface protein BASH2_00566 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BASH2_00567 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BASH2_00569 ENOG4105CAK Cell division ATP-binding protein ftsE BASH2_00570 ENOG4105CRP Part of the ABC transporter FtsEX involved in BASH2_00571 ENOG4105CN1 protease BASH2_00573 ENOG4105BZ1 (ABC) transporter BASH2_00576 ENOG4108WS4 fmn reductase BASH2_00578 ENOG4105DUM transcriptional regulator, lysR family BASH2_00585 ENOG4107TXC Transcriptional regulator BASH2_00588 ENOG4105D7V transposase BASH2_00589 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BASH2_00590 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BASH2_00592 ENOG41086DT Membrane protein of unknown function BASH2_00596 ENOG4108S4C acetyltransferase BASH2_00598 ENOG4105C3M thioredoxin reductase BASH2_00600 ENOG4108Z4K mutator MutT protein BASH2_00602 ENOG4105CHW UPF0052 protein BASH2_00604 ENOG4105KRI phosphocarrier protein (HPr BASH2_00605 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BASH2_00606 ENOG4105H67 Protein of unknown function (DUF421) BASH2_00609 ENOG4105CZ3 stage V sporulation protein ad BASH2_00610 ENOG41090VF Stage v sporulation protein ac BASH2_00614 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_00620 ENOG4105CP7 Triose-phosphate isomerase BASH2_00621 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BASH2_00623 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BASH2_00628 ENOG4105EFC phage portal protein HK97 family BASH2_00644 ENOG41067MG lrgb family BASH2_00645 ENOG4105XZU Preprotein translocase, subunit SecG BASH2_00647 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BASH2_00653 ENOG4105CM4 permease protein BASH2_00654 ENOG4108IPW abc transporter atp-binding protein BASH2_00657 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BASH2_00658 ENOG4108MK9 spermidine N(1)-acetyltransferase BASH2_00661 ENOG4105WMR Protein CrcB homolog BASH2_00663 ENOG4105WMR Protein CrcB homolog BASH2_00665 ENOG4105C8Q Methyl-accepting chemotaxis BASH2_00667 ENOG4105D4A Cell wall formation (By similarity) BASH2_00668 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BASH2_00671 ENOG4105KVH Transcriptional regulator BASH2_00672 ENOG4105F27 Major Facilitator BASH2_00673 ENOG4105CV8 reductase BASH2_00678 ENOG4108RYK Nad-dependent epimerase dehydratase BASH2_00681 ENOG4105D9N nucleoside BASH2_00682 ENOG4105D9N nucleoside BASH2_00687 ENOG4108URH decarboxylase BASH2_00690 ENOG4108RMU ferritin dps family protein BASH2_00692 ENOG4105NCW Trka-c domain protein BASH2_00693 ENOG4107S91 Sodium hydrogen exchanger BASH2_00697 ENOG4105D4Y metalloprotease BASH2_00698 ENOG4105VG1 fes assembly suf system protein BASH2_00701 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BASH2_00703 ENOG4105BZU Histidine kinase BASH2_00704 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_00705 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BASH2_00707 ENOG4107ZTW SNARE associated Golgi BASH2_00715 ENOG4107AYK membrAne BASH2_00717 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BASH2_00720 ENOG4107R7I amino acid BASH2_00721 ENOG4108SUT Major Facilitator Superfamily BASH2_00724 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BASH2_00728 ENOG4105DZ1 carboxypeptidase BASH2_00732 ENOG4105CHU acetyl-coa acetyltransferase BASH2_00734 ENOG4105C1G acyl-Coa dehydrogenase BASH2_00735 ENOG4108W8B Beta-lactamase domain protein BASH2_00741 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BASH2_00750 ENOG41080E8 Transcriptional regulator, Spx MgsR family BASH2_00757 ENOG4108UMI ABC transporter, permease BASH2_00758 ENOG4105D01 (LipO)protein BASH2_00759 ENOG4105D01 (LipO)protein BASH2_00761 ENOG4105C3K feS assembly ATPase SufC BASH2_00762 ENOG4105JRK feS assembly protein SufD BASH2_00763 ENOG4105C9B Cysteine desulfurase BASH2_00764 ENOG4108UNV SUF system FeS assembly protein, NifU family BASH2_00765 ENOG4105DIW FeS assembly protein SUFB BASH2_00768 ENOG4107R8B 5'-nucleotidase BASH2_00769 ENOG4105KZD Domain of unknown function (DUF1805) BASH2_00771 ENOG4105FAA peptidase M23 BASH2_00776 ENOG41090T1 Membrane BASH2_00777 ENOG4107TXC Transcriptional regulator BASH2_00778 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BASH2_00780 ENOG4105MMD transcriptional regulator BASH2_00783 ENOG4105CBT Fructose-1,6-bisphosphatase BASH2_00786 ENOG4105D4U had-superfamily hydrolase, subfamily iia BASH2_00787 ENOG4105DYS nad(p)h dehydrogenase (quinone) BASH2_00789 ENOG4108W5N phosphatidylglycerophosphatase a BASH2_00792 ENOG41083MR nifu domain-containing protein BASH2_00802 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BASH2_00803 ENOG4105C4B ABC transporter, permease BASH2_00804 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BASH2_00808 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BASH2_00812 ENOG4105EWC Purine nucleoside phosphorylase BASH2_00818 ENOG4105CEP NADH dehydrogenase BASH2_00821 ENOG41069ER domain protein BASH2_00825 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BASH2_00829 ENOG4105KA0 thioesterase Superfamily protein BASH2_00830 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BASH2_00834 ENOG4107R3E Citrate transporter BASH2_00836 ENOG4105Y38 Kinase-associated protein B BASH2_00839 ENOG4105C87 Aminotransferase class I and II BASH2_00841 ENOG4108MUZ hydrolase BASH2_00842 ENOG4105C5I Dehydrogenase BASH2_00843 ENOG4108ZB6 transcriptional regulator AsnC family BASH2_00844 ENOG4105CHM Aminotransferase BASH2_00846 ENOG4105WG9 Conserved Protein BASH2_00847 ENOG4107QYV phosphohexose isomerase BASH2_00849 ENOG4107PBV potassium channel BASH2_00850 ENOG4105KT7 mgtC SapB transporter BASH2_00852 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BASH2_00855 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BASH2_00857 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BASH2_00862 ENOG4105VEQ Cold shock protein BASH2_00864 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BASH2_00865 ENOG4105E4F Isochorismate synthase BASH2_00866 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BASH2_00867 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BASH2_00868 ENOG4108IPT Naphthoate synthase BASH2_00870 ENOG4105DTQ mandelate racemase muconate lactonizing BASH2_00876 ENOG41069H0 dihydroorotase EC 3.5.2.3 BASH2_00880 ENOG4105FDP GntR family transcriptional regulator BASH2_00881 ENOG4105C6Z Gluconate BASH2_00892 ENOG41086D8 Transcriptional regulator BASH2_00893 ENOG4105C19 ABC transporter BASH2_00896 ENOG4107ZTW SNARE associated Golgi BASH2_00902 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BASH2_00903 ENOG4108UGV hypoxanthine phosphoribosyltransferase BASH2_00908 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_00909 ENOG4105BZU Histidine kinase BASH2_00914 ENOG41087YS Phage shock protein A BASH2_00924 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BASH2_00925 ENOG4105C4M (Ubiquinol oxidase) subunit I BASH2_00926 ENOG4108V2W Carbonate dehydratase BASH2_00933 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BASH2_00936 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BASH2_00938 ENOG4105D2X ABC transporter substrate-binding protein BASH2_00942 ENOG4107T7U Sulfatase BASH2_00943 ENOG4107S9D Alpha beta hydrolase BASH2_00944 ENOG4105BZU Histidine kinase BASH2_00945 ENOG4105BZU Histidine kinase BASH2_00946 ENOG4105EGD dinuclear metal center protein, YbgI family BASH2_00956 ENOG4108RIR Molybdenum cofactor biosynthesis protein BASH2_00958 ENOG4105BZF Glycosyl transferase (Group 1 BASH2_00959 ENOG4105YVM Phosphoesterase, PA-phosphatase related BASH2_00960 ENOG4108Z0R Transferase BASH2_00961 ENOG4105E8V Alpha Beta Hydrolase Fold protein BASH2_00968 ENOG4105DA5 (ABC) transporter BASH2_00970 ENOG4105N5T Radical SAM Protein BASH2_00974 ENOG4105C19 ABC transporter BASH2_00977 ENOG4105NCW Trka-c domain protein BASH2_00978 ENOG4107S91 Sodium hydrogen exchanger BASH2_00979 ENOG410605W Major Facilitator BASH2_00989 ENOG4108B31 Spore germination protein BASH2_00991 ENOG4105DWV Homoserine O-trans-acetylase BASH2_00993 ENOG41085GJ domain protein BASH2_00997 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BASH2_00998 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BASH2_00999 ENOG4105D06 uba thif-type nad fad binding protein BASH2_01001 ENOG4105CVM Molybdenum cofactor synthesis domain protein BASH2_01002 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BASH2_01003 ENOG4108ZAF Molybdopterin BASH2_01006 ENOG4105CSC Glucose uptake protein BASH2_01007 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BASH2_01008 ENOG4108VJ1 Transcriptional regulator (CarD family BASH2_01015 ENOG4105CBX hi0933 family BASH2_01018 ENOG4105YW5 deoR family transcriptional regulator BASH2_01019 ENOG4107QSE Dipeptidase BASH2_01020 ENOG4107QSE Dipeptidase BASH2_01022 ENOG4108IUM Glycogen debranching enzyme BASH2_01023 ENOG4108V15 phosphotransferase enzyme family BASH2_01026 ENOG4105C8F Beta-lactamase domain protein BASH2_01032 ENOG4108VDD TRNA binding domain protein BASH2_01040 ENOG4105C88 aminopeptidase BASH2_01044 ENOG4105ETE Transcriptional regulator (LacI family BASH2_01050 ENOG4105EP9 oxidoreductase BASH2_01051 ENOG4107SNB ankyrin repeat protein YahD BASH2_01053 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_01055 ENOG4105DGU Histone deacetylase BASH2_01056 ENOG4105W87 Cbs domain BASH2_01057 ENOG4105F1V Acetoin utilization protein BASH2_01060 ENOG4105EMN RNA polymerase sigma factor BASH2_01062 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BASH2_01066 ENOG4105C28 cystathionine BASH2_01068 ENOG4105U5Y Transcriptional regulator BASH2_01069 ENOG4105U5Y Transcriptional regulator BASH2_01071 ENOG4106KR7 LysR family Transcriptional regulator BASH2_01076 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BASH2_01078 ENOG4105EFZ amidohydrolase BASH2_01081 ENOG4105KBJ sporulation protein ytfj BASH2_01082 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BASH2_01084 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BASH2_01088 ENOG4108JYZ YitT family BASH2_01097 ENOG4107YZX Universal stress protein BASH2_01101 ENOG4105VZ8 Transcriptional regulator BASH2_01103 ENOG41082W1 Cupin 2, conserved barrel domain protein BASH2_01104 ENOG4105Z7P Acetyltransferase (GNAT) family BASH2_01110 ENOG4105DC7 peptidase M24 BASH2_01118 ENOG4105SFS phosphoesterase RecJ domain protein BASH2_01120 ENOG4105VV2 BASH2_01121 ENOG4105C0B DNA polymerase III (alpha subunit) BASH2_01122 ENOG4105C6K Malic enzyme BASH2_01123 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BASH2_01128 ENOG4105FS0 cytoplasmic membrane protein BASH2_01129 ENOG4108REF Sporulation integral membrane protein ytvi BASH2_01131 ENOG4105BZN citrate synthase BASH2_01132 ENOG4108HMX isocitrate dehydrogenase (NADP) BASH2_01136 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_01137 ENOG4105BZU Histidine kinase BASH2_01138 ENOG4105C2M dna polymerase I BASH2_01139 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BASH2_01141 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BASH2_01142 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BASH2_01143 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BASH2_01147 ENOG4108TDW sporulation protein YtxC BASH2_01148 ENOG4105C22 threonyL-tRNA synthetase BASH2_01149 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BASH2_01153 ENOG4105CN9 Peptidase m42 family protein BASH2_01154 ENOG4108JGH Tetr family transcriptional regulator BASH2_01155 ENOG4105CW7 secretion protein, HlyD family BASH2_01156 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_01163 ENOG4108RWN rrna methyltransferase BASH2_01165 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BASH2_01166 ENOG4105C5S asparaginyl-tRNA synthetase BASH2_01172 ENOG4105DCG PHP domain protein BASH2_01175 ENOG4105FE9 pseudouridine synthase BASH2_01177 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BASH2_01179 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BASH2_01182 ENOG4105E0A ABC, transporter BASH2_01183 ENOG4105KFN sortase, SrtB family BASH2_01186 ENOG4105DR4 Methyltransferase BASH2_01189 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_01197 ENOG4105S6R Iron-hydroxamate transporter permease subunit BASH2_01198 ENOG4105J76 Periplasmic binding protein BASH2_01201 ENOG4105CEY Amp-dependent synthetase and ligase BASH2_01202 ENOG4107Z3H Transcriptional regulator, TetR family BASH2_01203 ENOG41060WC Enoyl-CoA hydratase BASH2_01204 ENOG4105BZJ Electron transfer flavoprotein BASH2_01205 ENOG4105C10 Electron transfer flavoprotein BASH2_01206 ENOG4105K63 Thioredoxin BASH2_01209 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BASH2_01211 ENOG4105E33 succinate dehydrogenase BASH2_01213 ENOG4108VXD carboxy-peptidase BASH2_01214 ENOG4105E14 MotA TolQ exbB proton channel BASH2_01215 ENOG4105ER2 Ompa motb domain protein BASH2_01216 ENOG4105ER2 Ompa motb domain protein BASH2_01217 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BASH2_01219 ENOG4108IUX (ABC) transporter BASH2_01220 ENOG4105RHA ABC transporter, permease BASH2_01221 ENOG4108Z40 Transcriptional regulator BASH2_01222 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BASH2_01224 ENOG4108JCI Transcriptional regulator BASH2_01225 ENOG41067S9 phage shock protein C, PspC BASH2_01228 ENOG4105DY9 regulatoR BASH2_01229 ENOG4108HRK Histidine kinase BASH2_01230 ENOG4108JQ7 (ABC) transporter BASH2_01233 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BASH2_01234 ENOG4105DEF Extracellular solute-binding protein, family 5 BASH2_01235 ENOG4105DZC cytosine deaminase BASH2_01236 ENOG4105DZC cytosine deaminase BASH2_01239 ENOG4105PFC Transcriptional regulator BASH2_01242 ENOG4105KBX Transcriptional regulator, TetR family BASH2_01244 ENOG4108PCX Major Facilitator BASH2_01246 ENOG4108XJQ germination protein BASH2_01249 ENOG4105M59 Phosphodiesterase, mj0936 family BASH2_01252 ENOG4108QCI YvbH-like oligomerisation region BASH2_01258 ENOG4108IUQ atp-dependent protease BASH2_01262 ENOG4105K56 Transcriptional regulator BASH2_01267 ENOG4105D52 delta-aminolevulinic acid dehydratase BASH2_01269 ENOG41068KH stage VI sporulation protein D BASH2_01271 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BASH2_01272 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BASH2_01277 ENOG4105DFF Rod shape-determining protein mreb BASH2_01278 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BASH2_01281 ENOG4107QMS site-determining protein BASH2_01284 ENOG4105C03 ribonuclease BASH2_01286 ENOG4105X36 (ribosomal) protein BASH2_01289 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BASH2_01291 ENOG4105EWM Histidine kinase BASH2_01295 ENOG4105CQC Prephenate dehydratase BASH2_01296 ENOG4108RPX mosc domain containing protein BASH2_01299 ENOG4108IYU L-aspartate oxidase BASH2_01300 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BASH2_01305 ENOG41082BM Transcriptional regulator, arsr family BASH2_01306 ENOG4108IPJ Membrane BASH2_01307 ENOG4108IPJ Membrane BASH2_01309 ENOG4108HUF Transporter BASH2_01312 ENOG41061AI Protein of unknown function (DUF2905) BASH2_01315 ENOG4105VIE preprotein translocase, subunit YajC BASH2_01317 ENOG4108QG2 Membrane BASH2_01318 ENOG4105CKP Polysaccharide Biosynthesis Protein BASH2_01320 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BASH2_01321 ENOG41076HS cation diffusion facilitator family transporter BASH2_01322 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BASH2_01324 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BASH2_01327 ENOG4105CUT histidyl-tRNA synthetase BASH2_01329 ENOG4105CUZ uba thif-type nad fad binding protein BASH2_01330 ENOG4108VCI transcription factor, rsfa family BASH2_01331 ENOG4105D1H recombination factor protein RarA BASH2_01333 ENOG4105C3J Cysteine desulfurase BASH2_01334 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BASH2_01336 ENOG4105C7H Helicase, RecD TraA family BASH2_01337 ENOG41060CR BASH2_01340 ENOG4105C02 permease BASH2_01343 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BASH2_01347 ENOG4105HHA aminodeoxychorismate lyase BASH2_01348 ENOG4108VQJ O-methyltransferase BASH2_01349 ENOG4105XYU peptidase (U32 family) BASH2_01350 ENOG4105CFP Peptidase U32 BASH2_01353 ENOG4107XRG penicillin-binding protein BASH2_01359 ENOG4105C28 cystathionine BASH2_01360 ENOG4108EKI Dehydrogenase BASH2_01362 ENOG4108V5C ABC transporter BASH2_01363 ENOG4105S6R Iron-hydroxamate transporter permease subunit BASH2_01371 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_01372 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_01374 ENOG4105MIR Phenylalanine 4-monooxygenase BASH2_01375 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BASH2_01382 ENOG4108MUZ hydrolase BASH2_01384 ENOG4105G6Z alkaline phosphatase BASH2_01387 ENOG4108TVJ Nitroreductase BASH2_01392 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_01395 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BASH2_01396 ENOG4105CQW ribosome biogenesis GTPase YqeH BASH2_01398 ENOG410812S Rna-binding protein BASH2_01400 ENOG4108WF2 Metal Dependent Phosphohydrolase BASH2_01402 ENOG4105DXX methyltransferase BASH2_01404 ENOG4105KQC Competence protein BASH2_01406 ENOG4108UK2 deaminase BASH2_01407 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BASH2_01409 ENOG4105TQK DNA polymerase iii, delta' subunit BASH2_01414 ENOG4105KVH Transcriptional regulator BASH2_01415 ENOG4105CSA Coproporphyrinogen iii oxidase BASH2_01417 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BASH2_01421 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BASH2_01422 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BASH2_01424 ENOG4105KTH gatB Yqey BASH2_01427 ENOG4105C9A Phoh family BASH2_01428 ENOG4105CTJ Metal Dependent Phosphohydrolase BASH2_01430 ENOG4107YR5 Diacylglycerol kinase BASH2_01431 ENOG4105KG3 cytidine deaminase BASH2_01432 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BASH2_01439 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BASH2_01440 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_01443 ENOG4105EGD dinuclear metal center protein, YbgI family BASH2_01448 ENOG41069ZM Protein of unknown function (DUF2624) BASH2_01449 ENOG4108JYZ YitT family BASH2_01450 ENOG4105FDK ABC transporter BASH2_01452 ENOG4105N80 Ferric uptake regulator, Fur family BASH2_01456 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BASH2_01458 ENOG4107RF6 penicillin-binding protein BASH2_01459 ENOG4105PWN phosphate abc transporter BASH2_01460 ENOG4105C8U phosphate abc transporter BASH2_01461 ENOG4105E2Z phosphate ABC transporter (Permease BASH2_01462 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BASH2_01463 ENOG4108UTW Plays a role in the regulation of phosphate uptake BASH2_01465 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BASH2_01467 ENOG4105DKQ ROK family BASH2_01468 ENOG4105C5X domain protein BASH2_01472 ENOG4105C28 cystathionine BASH2_01473 ENOG4105C28 cystathionine BASH2_01475 ENOG4105C3R Methionine synthase BASH2_01476 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BASH2_01501 ENOG4105C0D helicase BASH2_01507 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BASH2_01508 ENOG4105CJ1 ABC, transporter BASH2_01515 ENOG41080TC multidrug resistance protein BASH2_01519 ENOG4105WZW rhodanese family BASH2_01520 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BASH2_01524 ENOG4107YBY Hydrolase BASH2_01526 ENOG4105CBJ Metal-dependent enzyme BASH2_01529 ENOG4105DC7 peptidase M24 BASH2_01533 ENOG4105CD2 stage iii sporulation protein aa BASH2_01534 ENOG4105KR5 Stage iii sporulation protein BASH2_01535 ENOG4108CQH stage III sporulation protein AC BASH2_01536 ENOG4105KQ4 Stage iii sporulation protein ad BASH2_01538 ENOG410644B Stage III sporulation protein af BASH2_01542 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BASH2_01543 ENOG4108ZSR alkaline shock protein BASH2_01548 ENOG4105CTB Polyprenyl synthetase BASH2_01550 ENOG4105DX0 Hemolysin A BASH2_01552 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BASH2_01553 ENOG4105S1Z Stage IV sporulation protein B BASH2_01554 ENOG4107QQR Sporulation BASH2_01557 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BASH2_01559 ENOG4108JUB Transcriptional regulator BASH2_01561 ENOG4107RDP Dehydrogenase BASH2_01565 ENOG4105CPP Dehydrogenase, E1 component BASH2_01566 ENOG4105C7S Dehydrogenase BASH2_01568 ENOG4105E09 nadh pyrophosphatase BASH2_01569 ENOG4105G7B Protein of unknown function (DUF2992) BASH2_01571 ENOG4108HW3 (ABC) transporter BASH2_01572 ENOG4105E5Q amino acid AbC transporter BASH2_01573 ENOG4105CDA abc transporter atp-binding protein BASH2_01574 ENOG4108QEG Membrane BASH2_01575 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BASH2_01578 ENOG4105D9U N-acetyltransferase BASH2_01579 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BASH2_01585 ENOG4105EJQ L-serine dehydratase BASH2_01586 ENOG4105II7 pyrroline-5-carboxylate reductase BASH2_01588 ENOG41069FQ Metallo-beta-lactamase superfamily BASH2_01589 ENOG4108IXY short-chain dehydrogenase reductase BASH2_01592 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BASH2_01600 ENOG4105CGH 5'-nucleotidase BASH2_01601 ENOG4105DFD Na H antiporter BASH2_01604 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BASH2_01606 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BASH2_01607 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BASH2_01608 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BASH2_01609 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BASH2_01613 ENOG4108R6K riboflavin synthase, subunit alpha BASH2_01614 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BASH2_01618 ENOG4108YM7 Gcn5-related n-acetyltransferase BASH2_01619 ENOG4105ETE Transcriptional regulator (LacI family BASH2_01621 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BASH2_01625 ENOG4105RHY Pfam:UPF0157 BASH2_01627 ENOG4105CPC Aldo Keto reductase BASH2_01631 ENOG4105MZ9 stage II sporulation protein m BASH2_01632 ENOG4105I3K Ferric uptake regulator, Fur family BASH2_01634 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BASH2_01639 ENOG4105D7N magnesium and cobalt transport protein CorA BASH2_01646 ENOG4105DVE abc transporter atp-binding protein BASH2_01647 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BASH2_01648 ENOG4105DZ1 carboxypeptidase BASH2_01650 ENOG41082AN stage II sporulation protein BASH2_01652 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_01653 ENOG4105C8J )-transporter BASH2_01657 ENOG41090VF Stage v sporulation protein ac BASH2_01658 ENOG4105CZ3 stage V sporulation protein ad BASH2_01660 ENOG4105G6R Stage v sporulation protein ae BASH2_01662 ENOG4105J7I hydrolase BASH2_01663 ENOG4105PTM secreted protein BASH2_01664 ENOG4107ZE5 PPIases accelerate the folding of proteins BASH2_01671 ENOG4105CE4 GlcNAc 6-P deacetylase BASH2_01673 ENOG4105FDP GntR family transcriptional regulator BASH2_01675 ENOG4105CID antiterminator BASH2_01678 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BASH2_01682 ENOG4106TD9 Diguanylate cyclase BASH2_01683 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BASH2_01684 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BASH2_01687 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BASH2_01692 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BASH2_01695 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BASH2_01697 ENOG4105DTD Dehydrogenase BASH2_01698 ENOG4105K7K Transcriptional regulator BASH2_01705 ENOG4105CHU acetyl-coa acetyltransferase BASH2_01714 ENOG4105CG3 alpha amylase, catalytic region BASH2_01716 ENOG4107FKK extracellular solute-binding protein family 1 BASH2_01718 ENOG4105EG2 ABC transporter, permease BASH2_01719 ENOG4105FKQ transcriptional regulator BASH2_01720 ENOG4105CHM Aminotransferase BASH2_01722 ENOG4108HGU Histidine kinase BASH2_01735 ENOG4105UIN BASH2_01737 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BASH2_01739 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BASH2_01740 ENOG4105EPM Diguanylate phosphodiesterase BASH2_01743 ENOG4107IN1 Protein of unknown function (DUF1797) BASH2_01744 ENOG4108XRC Protein of unknown function (DUF458) BASH2_01751 ENOG4107ZYR domain protein BASH2_01752 ENOG4105CN5 Metallo-Beta-Lactamase BASH2_01754 ENOG4108X4Q Hydrolase BASH2_01755 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BASH2_01758 ENOG4105CPP Dehydrogenase, E1 component BASH2_01759 ENOG4105C7S Dehydrogenase BASH2_01767 ENOG4105CXN decarboxylase BASH2_01771 ENOG4105ECY inositol monophosphatase BASH2_01773 ENOG4105CI3 gtp-binding protein typa BASH2_01774 ENOG4105QA2 BASH2_01778 ENOG4108IAB Phoh family BASH2_01781 ENOG4105CNI cell division protein FtsW BASH2_01782 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BASH2_01792 ENOG4106UY4 Inherit from COG: Scp-like extracellular BASH2_01795 ENOG4107TB6 phosphoglycerate mutase BASH2_01801 ENOG4106H78 methyltransferase BASH2_01804 ENOG4105H20 Sporulation integral membrane protein YlbJ BASH2_01805 ENOG4105D78 K07001 NTE family protein BASH2_01806 ENOG41063PX domain protein BASH2_01808 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BASH2_01815 ENOG4108IMY Transcriptional regulator BASH2_01825 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_01827 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BASH2_01844 ENOG4105CAR Terminase, large subunit BASH2_01846 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BASH2_01865 ENOG4105XSJ toxin secretion phage lysis holin BASH2_01875 ENOG4105KNH Nucleic acid-binding protein BASH2_01881 ENOG41068DC Essential cell division protein (By similarity) BASH2_01882 ENOG4105CJN penicillin-binding protein BASH2_01883 ENOG4105CJN penicillin-binding protein BASH2_01884 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BASH2_01887 ENOG4105CNI cell division protein FtsW BASH2_01888 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BASH2_01889 ENOG4105D4A Cell wall formation (By similarity) BASH2_01890 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BASH2_01891 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BASH2_01892 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BASH2_01894 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_01896 ENOG4105WR5 sporulation protein, YlmC YmxH family BASH2_01897 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BASH2_01898 ENOG4105DFA alanine racemase domain protein BASH2_01900 ENOG41067XK integral membrane protein BASH2_01901 ENOG4105DBK s4 domain protein BASH2_01903 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BASH2_01906 ENOG4105C34 Pseudouridine synthase BASH2_01911 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BASH2_01923 ENOG4105DC7 peptidase M24 BASH2_01924 ENOG4105F23 Fibronectin-binding protein BASH2_01926 ENOG4105DSJ YicC domain protein BASH2_01930 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BASH2_01931 ENOG4105C25 Primosomal protein n' BASH2_01932 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BASH2_01934 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BASH2_01936 ENOG4108ZF3 Phosphatase BASH2_01937 ENOG4105D9P serine threonine protein kinase BASH2_01938 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BASH2_01939 ENOG4105DJV ribulose-phosphate 3-epimerase BASH2_01940 ENOG4105FJ0 thiamine BASH2_01942 ENOG4108ZAA Alkaline-shock protein BASH2_01943 ENOG4105DP4 dak2 domain fusion protein ylov BASH2_01944 ENOG4105CB5 ATP-dependent DNA helicase recG BASH2_01947 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BASH2_01948 ENOG4105CHR reductase BASH2_01951 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BASH2_01952 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BASH2_01956 ENOG4105VB6 UPF0109 protein BASH2_01961 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BASH2_01964 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BASH2_01966 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BASH2_01968 ENOG4108HE4 integrase family BASH2_01976 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BASH2_01977 ENOG4105KNE Phosphatidate cytidylyltransferase BASH2_01978 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BASH2_01979 ENOG4105DZP Membrane-associated zinc metalloprotease BASH2_01982 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BASH2_01984 ENOG4105CHV Transcription elongation factor NusA BASH2_01985 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BASH2_01986 ENOG4105VHM ribosomal protein BASH2_01988 ENOG4105W7A Protein of unknown function (DUF503) BASH2_01990 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BASH2_01991 ENOG4105DTN riboflavin biosynthesis protein ribF BASH2_01994 ENOG4105C1V Peptidase, M16 BASH2_01996 ENOG4105E35 Dipicolinate synthase subunit A BASH2_01997 ENOG4108S0H Dipicolinic acid synthetase, b subunit BASH2_01998 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BASH2_02000 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BASH2_02002 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BASH2_02004 ENOG4107QZI cell division protein FtsK BASH2_02005 ENOG4105FDP GntR family transcriptional regulator BASH2_02006 ENOG4105DIH basic membrane BASH2_02007 ENOG4108JQ9 ABC transporter BASH2_02008 ENOG4105UIB (ABC) transporter BASH2_02009 ENOG4105UIB (ABC) transporter BASH2_02013 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BASH2_02014 ENOG4105XZV Protein of unknown function (DUF3243) BASH2_02018 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BASH2_02023 ENOG4105D48 metallophosphoesterase BASH2_02024 ENOG4105MCT stage V sporulation protein S BASH2_02025 ENOG4108IGT Dipeptidase BASH2_02026 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BASH2_02027 ENOG4105DQU oxidoreductase, subunit beta BASH2_02028 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BASH2_02033 ENOG4105DA5 (ABC) transporter BASH2_02038 ENOG4107QHE Choloylglycine hydrolase BASH2_02040 ENOG410890F Dynamin family BASH2_02041 ENOG4105E0M Sulfatase BASH2_02042 ENOG4107R6R udp-galactopyranose mutase BASH2_02043 ENOG4105F0V Cell wall hydrolase BASH2_02048 ENOG4107YEI lmbE family BASH2_02049 ENOG4107TTQ Alpha beta hydrolase fold BASH2_02052 ENOG41067MG lrgb family BASH2_02056 ENOG4105BZU Histidine kinase BASH2_02057 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_02063 ENOG4105D03 DNA-3-methyladenine glycosylase II BASH2_02064 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BASH2_02066 ENOG4105CGK Exodeoxyribonuclease III BASH2_02071 ENOG4105E0A ABC, transporter BASH2_02072 ENOG4105NIV Esterase BASH2_02074 ENOG4105VPX protein, conserved in bacteria BASH2_02075 ENOG410681U heavy metal transport detoxification protein BASH2_02076 ENOG4105C59 p-type ATPase BASH2_02077 ENOG4105K70 DNA-binding protein BASH2_02078 ENOG4105TMB Formate nitrite transporter BASH2_02082 ENOG4105C85 amino acid BASH2_02085 ENOG4108SJC Membrane BASH2_02086 ENOG4107QW4 alcohol dehydrogenase BASH2_02087 ENOG4107QW4 alcohol dehydrogenase BASH2_02088 ENOG4105E98 transcriptional regulator DeoR family BASH2_02089 ENOG4105DE4 1-phosphofructokinase BASH2_02090 ENOG4105DM4 PTS System BASH2_02091 ENOG41069ER domain protein BASH2_02098 ENOG4106F1P AAA ATPase, central domain protein BASH2_02099 ENOG4105EN6 Membrane BASH2_02100 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BASH2_02101 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BASH2_02102 ENOG4105CXI aluminum resistance protein BASH2_02103 ENOG4105KV4 Transcriptional regulator BASH2_02104 ENOG4105C5F glutamine synthetase BASH2_02124 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BASH2_02162 ENOG4105XSJ toxin secretion phage lysis holin BASH2_02163 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BASH2_02169 ENOG4105K7K Transcriptional regulator BASH2_02173 ENOG4108SVB resolvase BASH2_02175 ENOG4105CGH 5'-nucleotidase BASH2_02178 ENOG4105D5T phosphonate abc transporter BASH2_02181 ENOG4105D7V transposase BASH2_02185 ENOG4105BZ1 (ABC) transporter BASH2_02186 ENOG4105BZ1 (ABC) transporter BASH2_02189 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BASH2_02195 ENOG41067MG lrgb family BASH2_02196 ENOG4105VAW lrga family BASH2_02197 ENOG4107RSM transcriptional regulator BASH2_02200 ENOG4107QIV Cytochrome c biogenesis protein BASH2_02218 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BASH2_02223 ENOG4108903 Formimidoylglutamase BASH2_02224 ENOG4108VJ1 Transcriptional regulator (CarD family BASH2_02225 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BASH2_02226 ENOG4105CBC glutamate synthase BASH2_02227 ENOG4105CK7 Sodium proline symporter BASH2_02228 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BASH2_02229 ENOG4105FBA Phospholipase Carboxylesterase BASH2_02230 ENOG4105BZU Histidine kinase BASH2_02232 ENOG4107AYK membrAne BASH2_02241 ENOG4105CEY Amp-dependent synthetase and ligase BASH2_02242 ENOG4107ZYJ bioY protein BASH2_02243 ENOG4107F3J Amp-dependent synthetase and ligase BASH2_02247 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BASH2_02249 ENOG4105E5W Transporter BASH2_02254 ENOG4108I0Z Aconitate hydratase BASH2_02255 ENOG4108JJA ABC, transporter BASH2_02256 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BASH2_02257 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BASH2_02263 ENOG4105W8X HesB YadR YfhF-family protein BASH2_02264 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BASH2_02266 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BASH2_02269 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_02270 ENOG4105C0H protease BASH2_02271 ENOG4105K4P CoA-binding domain protein BASH2_02272 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BASH2_02274 ENOG4105D9R oxidoreductase BASH2_02276 ENOG4105CIG ABC transporter BASH2_02281 ENOG4105EMN RNA polymerase sigma factor BASH2_02283 ENOG4108KGH TRANSCRIPTIONal BASH2_02284 ENOG4107QJT sodium dicarboxylate symporter BASH2_02285 ENOG4107QJT sodium dicarboxylate symporter BASH2_02298 ENOG4105E1K spore germination protein BASH2_02299 ENOG4108JB9 formate dehydrogenase BASH2_02301 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BASH2_02302 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BASH2_02305 ENOG4105TMB Formate nitrite transporter BASH2_02306 ENOG4105D06 uba thif-type nad fad binding protein BASH2_02307 ENOG4105CVM Molybdenum cofactor synthesis domain protein BASH2_02308 ENOG4108ZAF Molybdopterin BASH2_02310 ENOG4105D1F ATP-binding protein BASH2_02313 ENOG410696E Membrane BASH2_02314 ENOG4105FR1 rard protein BASH2_02316 ENOG4105EWU Squalene--hopene cyclase BASH2_02318 ENOG4105CHR reductase BASH2_02319 ENOG4105C26 Dehydrogenase BASH2_02321 ENOG4108IA2 Sodium pantothenate symporter BASH2_02324 ENOG4106IQC argininosuccinate lyase BASH2_02326 ENOG410904N short-chain dehydrogenase reductase BASH2_02330 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BASH2_02334 ENOG4105VEQ Cold shock protein BASH2_02338 ENOG4108R1P BASH2_02340 ENOG41073R8 VanW family BASH2_02341 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_02343 ENOG4105KT7 mgtC SapB transporter BASH2_02345 ENOG4105E39 Enoyl-CoA hydratase BASH2_02346 ENOG4105K64 Glycosyl transferase, family 2 BASH2_02348 ENOG4108UT6 Transferase hexapeptide repeat containing protein BASH2_02353 ENOG4105CQB FAD linked oxidase domain protein BASH2_02354 ENOG4105C09 Bile acid BASH2_02355 ENOG4105RHY Pfam:UPF0157 BASH2_02361 ENOG4105CIS alcohol dehydrogenase BASH2_02362 ENOG41082BM Transcriptional regulator, arsr family BASH2_02366 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BASH2_02372 ENOG4108A04 Beta-lactamase BASH2_02373 ENOG4105DPN Oligoendopeptidase f BASH2_02374 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BASH2_02375 ENOG4105E5K Alpha-amylase BASH2_02378 ENOG4105C98 muts2 protein BASH2_02382 ENOG4107V2S Transcriptional regulator BASH2_02385 ENOG4107CUJ Protein of unknown function (DUF2690) BASH2_02389 ENOG4107ZY0 Phenazine biosynthesis-like protein BASH2_02390 ENOG4105NX3 Membrane BASH2_02391 ENOG4105DQ5 transport system permease protein BASH2_02392 ENOG4105EHG Permease protein BASH2_02394 ENOG4108MES Periplasmic binding protein BASH2_02399 ENOG4107R3E Citrate transporter BASH2_02401 ENOG4108TN2 lmbE family BASH2_02408 ENOG4105CIS alcohol dehydrogenase BASH2_02409 ENOG4105CIS alcohol dehydrogenase BASH2_02416 ENOG4105H3G oxidoreductase BASH2_02418 ENOG4105ED2 Beta-lactamase BASH2_02423 ENOG4107YXZ hydrolase, family 25 BASH2_02427 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BASH2_02433 ENOG4105KAF membrAne BASH2_02442 ENOG4108ZJ4 polysaccharide deacetylase BASH2_02447 ENOG4105KVH Transcriptional regulator BASH2_02448 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BASH2_02452 ENOG4105CHR reductase BASH2_02454 ENOG4105JAB phenazine biosynthesis protein, phzf family BASH2_02461 ENOG4105KVH Transcriptional regulator BASH2_02462 ENOG4105KVH Transcriptional regulator BASH2_02463 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BASH2_02465 ENOG4105D9R oxidoreductase BASH2_02466 ENOG4108TZY GntR Family Transcriptional Regulator BASH2_02467 ENOG4105KVH Transcriptional regulator BASH2_02474 ENOG4105C44 Serine transporter BASH2_02475 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BASH2_02478 ENOG4105F27 Major Facilitator BASH2_02479 ENOG4105CV8 reductase BASH2_02483 ENOG4105D4Y metalloprotease BASH2_02484 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BASH2_02487 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BASH2_02488 ENOG4105CIS alcohol dehydrogenase BASH2_02489 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BASH2_02490 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BASH2_02493 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BASH2_02494 ENOG4105C6Z Gluconate BASH2_02495 ENOG4105CMG Carbohydrate kinase BASH2_02496 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BASH2_02497 ENOG4105DDN Pentapeptide repeat-containing protein BASH2_02500 ENOG4105C37 (CBS) domain BASH2_02506 ENOG4105EV4 Multidrug resistance protein mdtH BASH2_02508 ENOG4105DMQ Methyltransferase BASH2_02512 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BASH2_02513 ENOG4105C31 Tryptophanyl-tRNA synthetase BASH2_02515 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BASH2_02518 ENOG4108UW5 maltose o-acetyltransferase BASH2_02519 ENOG4106UW1 Major Facilitator superfamily BASH2_02520 ENOG4105DKQ ROK family BASH2_02521 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_02533 ENOG4105CJ1 ABC, transporter BASH2_02535 ENOG4108PSK reductase BASH2_02539 ENOG4108RCM Nitroreductase BASH2_02540 ENOG4105KVH Transcriptional regulator BASH2_02542 ENOG4105CUT histidyl-tRNA synthetase BASH2_02543 ENOG4108Z66 YbaK ebsC protein BASH2_02545 ENOG41067QW Transcriptional regulator BASH2_02548 ENOG4108K8S endonuclease I BASH2_02553 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BASH2_02554 ENOG4108JJB ABC transporter BASH2_02560 ENOG4105DYS nad(p)h dehydrogenase (quinone) BASH2_02562 ENOG4105CRW Short chain fatty acid transporter BASH2_02564 ENOG4105KBX Transcriptional regulator, TetR family BASH2_02565 ENOG4105KPY Small multidrug resistance protein BASH2_02567 ENOG4105DA5 (ABC) transporter BASH2_02571 ENOG4105CZM Major Facilitator BASH2_02572 ENOG4107MII Sugar-specific transcriptional regulator TrmB BASH2_02574 ENOG4108ISG Major Facilitator BASH2_02582 ENOG4105HIR S-layer domain protein BASH2_02586 ENOG410874W AraC family transcriptional regulator BASH2_02587 ENOG41082W1 Cupin 2, conserved barrel domain protein BASH2_02590 ENOG4108AEY RNA polymerase sigma factor BASH2_02594 ENOG4108JQ1 Dehydrogenase BASH2_02597 ENOG4105DVH amino acid BASH2_02599 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BASH2_02603 ENOG4108JPW Aminotransferase BASH2_02607 ENOG4105EJQ L-serine dehydratase BASH2_02609 ENOG4105C44 Serine transporter BASH2_02611 ENOG4108JGH Tetr family transcriptional regulator BASH2_02612 ENOG4105EQ0 Major Facilitator superfamily BASH2_02613 ENOG4105MZU cell filamentation protein BASH2_02617 ENOG4107QJQ Mate efflux family protein BASH2_02624 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BASH2_02632 ENOG4105TRI Hydrolase BASH2_02637 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BASH2_02639 ENOG4106P55 Transcriptional regulator BASH2_02641 ENOG4107QR9 Iron-sulfur cluster binding protein BASH2_02642 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BASH2_02644 ENOG4105DJB Major Facilitator Superfamily BASH2_02645 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BASH2_02647 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BASH2_02648 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BASH2_02649 ENOG4108U05 Transcriptional regulator BASH2_02652 ENOG4105BZU Histidine kinase BASH2_02655 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BASH2_02656 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BASH2_02659 ENOG4105JQZ Methyltransferase BASH2_02660 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BASH2_02662 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BASH2_02663 ENOG4108NNI Beta-lactamase domain-containing protein BASH2_02666 ENOG4105VZ8 Transcriptional regulator BASH2_02672 ENOG4105K6H D-cysteine desulfhydrase BASH2_02677 ENOG41062D9 Histidine kinase BASH2_02678 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_02681 ENOG4105IIP Membrane BASH2_02683 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_02684 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BASH2_02697 ENOG4108YXU transcriptional regulator AsnC family BASH2_02698 ENOG4105CHR reductase BASH2_02700 ENOG4105F7F Chaperone BASH2_02703 ENOG41085FC arsR family transcriptional regulator BASH2_02704 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_02705 ENOG4105D6J arsenicaL-resistance protein BASH2_02711 ENOG4105DIK (ABC) transporter BASH2_02712 ENOG4105CC5 ABC transporter BASH2_02713 ENOG4105DSE periplasmic solute binding protein BASH2_02715 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BASH2_02716 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BASH2_02718 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BASH2_02719 ENOG4108TWJ NADH dehydrogenase subunit 5 BASH2_02722 ENOG4105CVP deoxyribo-dipyrimidine photolyase BASH2_02723 ENOG4108606 TspO/MBR family BASH2_02731 ENOG41090MY MarR family Transcriptional regulator BASH2_02737 ENOG4105CHJ isochorismatase hydrolase BASH2_02739 ENOG4105CH6 catalase BASH2_02740 ENOG4105CGH 5'-nucleotidase BASH2_02747 ENOG4105CSV Glutaminase BASH2_02753 ENOG4108Q8B Spore germination protein BASH2_02754 ENOG4108NHD germination protein BASH2_02755 ENOG4108NHD germination protein BASH2_02757 ENOG4105C6K Malic enzyme BASH2_02759 ENOG4105II7 pyrroline-5-carboxylate reductase BASH2_02761 ENOG4105CUB amino acid BASH2_02762 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BASH2_02764 ENOG4108IMY Transcriptional regulator BASH2_02765 ENOG4105HDK L-asparaginase BASH2_02766 ENOG4108IJ0 Aspartate ammonia-lyase BASH2_02770 ENOG4105E2A Dehydrogenase BASH2_02785 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BASH2_02791 ENOG4105DWD nucleoside recognition domain protein BASH2_02795 ENOG4105FDT acyl-CoA dehydrogenase BASH2_02797 ENOG4108ZHR arsR family transcriptional regulator BASH2_02798 ENOG4108ZRV stage ii sporulation protein p BASH2_02799 ENOG4106N3A copper homeostasis protein cutc BASH2_02801 ENOG4107258 Transcriptional regulator BASH2_02802 ENOG4105P4J Allophanate hydrolase, subunit 1 BASH2_02810 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BASH2_02812 ENOG4107RF6 penicillin-binding protein BASH2_02821 ENOG4105F1N DNA alkylation repair BASH2_02823 ENOG4108IQI permease BASH2_02824 ENOG4105KNA -acetyltransferase BASH2_02825 ENOG410635A Membrane BASH2_02841 ENOG4108XET gCN5-related N-acetyltransferase BASH2_02847 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BASH2_02850 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BASH2_02858 ENOG4105FS7 Transcriptional regulator BASH2_02859 ENOG4108TVJ Nitroreductase BASH2_02861 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BASH2_02870 ENOG4105C8Y Acetylornithine aminotransferase BASH2_02873 ENOG4105CKK Glycosyl transferase, family 2 BASH2_02877 ENOG4105CKK Glycosyl transferase, family 2 BASH2_02882 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BASH2_02886 ENOG41068WN BASH2_02888 ENOG4108WCX response regulator BASH2_02890 ENOG41090T1 Membrane BASH2_02893 ENOG4105VMP Transcriptional regulator BASH2_02895 ENOG4105G6Z alkaline phosphatase BASH2_02896 ENOG4105ECK Fatty Acid Desaturase BASH2_02897 ENOG4105E0Y RtcB Protein BASH2_02899 ENOG4107258 Transcriptional regulator BASH2_02901 ENOG4105II7 pyrroline-5-carboxylate reductase BASH2_02902 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BASH2_02908 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BASH2_02913 ENOG41061GT Aldolase BASH2_02916 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BASH2_02917 ENOG4105DKT Transcriptional regulator BASH2_02919 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BASH2_02921 ENOG4105D4B ABC, transporter BASH2_02926 ENOG4105EMN RNA polymerase sigma factor BASH2_02929 ENOG41069ER domain protein BASH2_02937 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BASH2_02938 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BASH2_02939 ENOG4105CIH Imidazole acetol-phosphate transaminase BASH2_02943 ENOG41082JN Transcriptional regulator BASH2_02944 ENOG4105EYF MMPL domain protein BASH2_02945 ENOG4105EYF MMPL domain protein BASH2_02946 ENOG4105EYF MMPL domain protein BASH2_02948 ENOG4105C5H ABC transporter BASH2_02949 ENOG4105E0M Sulfatase BASH2_02950 ENOG4108ZCF integral membrane protein BASH2_02952 ENOG4107VMI polysaccharide deacetylase BASH2_02955 ENOG4107VC0 DNA alkylation repair enzyme BASH2_02965 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BASH2_02969 ENOG4105E09 nadh pyrophosphatase BASH2_02974 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BASH2_02975 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BASH2_02976 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BASH2_02979 ENOG4105C02 permease BASH2_02987 ENOG4105DVE abc transporter atp-binding protein BASH2_02994 ENOG4105CHM Aminotransferase BASH2_03001 ENOG41089UC methyltransferase, type 11 BASH2_03004 ENOG4107BMA Transglycosylase associated protein BASH2_03008 ENOG4106K7D Major facilitator family transporter BASH2_03009 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BASH2_03016 ENOG4105EPR degv family BASH2_03019 ENOG4105DPN Oligoendopeptidase f BASH2_03026 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_03027 ENOG4105BZU Histidine kinase BASH2_03028 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BASH2_03037 ENOG4105DTQ mandelate racemase muconate lactonizing BASH2_03040 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BASH2_03041 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BASH2_03044 ENOG4107T5V SNARE associated Golgi BASH2_03052 ENOG41080HI glycine oxidase BASH2_03053 ENOG4105CTU Proline racemase BASH2_03054 ENOG4105CTU Proline racemase BASH2_03055 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BASH2_03056 ENOG4105C26 Dehydrogenase BASH2_03057 ENOG4105BZG amino acid carrier protein BASH2_03060 ENOG4108M1A Chitin-binding protein BASH2_03067 ENOG4105C9U ATP-dependent DNA helicase RecQ BASH2_03072 ENOG4105EEM helicase BASH2_03083 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BASH2_03093 ENOG4108M1A Chitin-binding protein BASH2_03094 ENOG41082BV acetyltransferase BASH2_03095 ENOG4105E66 phosphoriboisomerase A BASH2_03100 ENOG4108IJ7 Glycine betaine BASH2_03101 ENOG4107SQ8 Glycine betaine BASH2_03106 ENOG4105RHY Pfam:UPF0157 BASH2_03107 ENOG4105E1F short-chain dehydrogenase reductase BASH2_03109 ENOG4107RUY (E1 component), alpha subunit BASH2_03111 ENOG4107QKR Dehydrogenase BASH2_03116 ENOG41062ES Transcriptional regulator BASH2_03120 ENOG4105E98 transcriptional regulator DeoR family BASH2_03124 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BASH2_03130 ENOG4107Z3H Transcriptional regulator, TetR family BASH2_03131 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BASH2_03132 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BASH2_03133 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BASH2_03137 ENOG4105MSI germination protein ypeb BASH2_03141 ENOG4108V3A UPF0421 protein BASH2_03148 ENOG4105FDR Membrane BASH2_03150 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BASH2_03155 ENOG4108IUM Glycogen debranching enzyme BASH2_03158 ENOG4105DY8 decarboxylase BASH2_03162 ENOG4105PAD Hydrolase BASH2_03167 ENOG4107VFR oxidoreductase BASH2_03174 ENOG4105PKS Excinuclease abc c subunit domain protein BASH2_03182 ENOG4105KWG Pfam:DUF1696 BASH2_03188 ENOG4108XI2 Domain of unknown function (DUF1963) BASH2_03195 ENOG4108Z4K mutator MutT protein BASH2_03196 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BASH2_03197 ENOG4105E09 nadh pyrophosphatase BASH2_03200 ENOG4105FCD Major Facilitator BASH2_03208 ENOG4107Y9U Membrane BASH2_03213 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BASH2_03217 ENOG4107Y80 Major Facilitator superfamily BASH2_03224 ENOG4108V4B ThiJ pfpI BASH2_03231 ENOG4105FQP Beta-lactamase BASH2_03233 ENOG4105CJN penicillin-binding protein BASH2_03234 ENOG4105CB2 alcohol dehydrogenase BASH2_03237 ENOG4108HGU Histidine kinase BASH2_03240 ENOG4108JJB ABC transporter BASH2_03244 ENOG4107RF6 penicillin-binding protein BASH2_03245 ENOG4105BZU Histidine kinase BASH2_03246 ENOG410667J hydrolase BASH2_03265 ENOG4105ETU transcriptional activator (TenA BASH2_03286 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BASH2_03287 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BASH2_03291 ENOG4105CPQ Dehydrogenase BASH2_03297 ENOG4105CUV Homoserine Kinase BASH2_03301 ENOG4107Y80 Major Facilitator superfamily BASH2_03303 ENOG4105FQP Beta-lactamase BASH2_03306 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BASH2_03306 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BASH2_03315 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BASH2_03317 ENOG4105T9C HD domain BASH2_03320 ENOG4105DZ1 carboxypeptidase BASH2_03323 ENOG4105DBI uridine monophosphokinase BASH2_03324 ENOG4105WCN acetyltransferase BASH2_03326 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BASH2_03327 ENOG4107QX3 carboxylase BASH2_03328 ENOG4105E39 Enoyl-CoA hydratase BASH2_03329 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BASH2_03330 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BASH2_03331 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BASH2_03332 ENOG4105C1G acyl-Coa dehydrogenase BASH2_03335 ENOG4107Z3H Transcriptional regulator, TetR family BASH2_03337 ENOG4105CJ1 ABC, transporter BASH2_03339 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BASH2_03340 ENOG4105CEP NADH dehydrogenase BASH2_03341 ENOG4106ANW SMI1_KNR4 BASH2_03344 ENOG4105BZU Histidine kinase BASH2_03346 ENOG4105C5H ABC transporter BASH2_03347 ENOG41067SE Tetr family transcriptional regulator BASH2_03348 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BASH2_03352 ENOG4108VXD carboxy-peptidase BASH2_03354 ENOG4105VZ8 Transcriptional regulator BASH2_03357 ENOG4105CGH 5'-nucleotidase BASH2_03359 ENOG4105CGH 5'-nucleotidase BASH2_03363 ENOG4105DH8 myo-inositol catabolism BASH2_03364 ENOG4105D2N Aldolase BASH2_03370 ENOG4105CK5 oxidoreductase BASH2_03371 ENOG4105IE8 Alpha-ketoglutarate permease BASH2_03372 ENOG4105ETE Transcriptional regulator (LacI family BASH2_03373 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BASH2_03375 ENOG4107RF6 penicillin-binding protein BASH2_03376 ENOG4107RF6 penicillin-binding protein BASH2_03377 ENOG4107RF6 penicillin-binding protein BASH2_03383 ENOG4105CIN aminoacyl-histidine dipeptidase BASH2_03391 ENOG41090HR transcriptional regulator BASH2_03392 ENOG4107RA9 decarboxylase BASH2_03393 ENOG4108I0C methyltransferase BASH2_03395 ENOG41088CC tellurite resistance protein tehB BASH2_03399 ENOG4108RZE Tetr family transcriptional regulator BASH2_03402 ENOG4105C1J atp-dependent rna helicase BASH2_03405 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BASH2_03410 ENOG4107STF Involved in phosphonate degradation (By similarity) BASH2_03412 ENOG4105RD7 BadF BadG BcrA BcrD BASH2_03418 ENOG4105F32 YngK protein BASH2_03424 ENOG4108KPJ rna polymerase sigma factor BASH2_03430 ENOG4108JCI Transcriptional regulator BASH2_03433 ENOG4105BZ1 (ABC) transporter BASH2_03434 ENOG4105BZ1 (ABC) transporter BASH2_03437 ENOG4108RPX mosc domain containing protein BASH2_03438 ENOG4105DND Transcriptional regulator BASH2_03441 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BASH2_03442 ENOG4107V2S Transcriptional regulator BASH2_03448 ENOG410667J hydrolase BASH2_03452 ENOG4105VEQ Cold shock protein BASH2_03454 ENOG41068WN BASH2_03456 ENOG4105C1Q protoporphyrinogen oxidase BASH2_03462 ENOG4105WCN acetyltransferase BASH2_03467 ENOG4105EYF MMPL domain protein BASH2_03469 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BASH2_03472 ENOG41081I9 integral membrane protein BASH2_03478 ENOG4108D32 Methyltransferase BASH2_03483 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BASH2_03486 ENOG4105C19 ABC transporter BASH2_03487 ENOG4105C22 threonyL-tRNA synthetase BASH2_03488 ENOG4105FE9 pseudouridine synthase BASH2_03492 ENOG4105BZG amino acid carrier protein BASH2_03496 ENOG4105K70 DNA-binding protein BASH2_03499 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_03500 ENOG4105WQT MbtH domain protein BASH2_03501 ENOG4105CEY Amp-dependent synthetase and ligase BASH2_03502 ENOG4105WQI isochorismatase BASH2_03503 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BASH2_03504 ENOG4105E4F Isochorismate synthase BASH2_03505 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BASH2_03506 ENOG4105FCD Major Facilitator BASH2_03513 ENOG4105EYH Exonuclease BASH2_03514 ENOG4107RFY SbcCD D subunit BASH2_03517 ENOG4105E39 Enoyl-CoA hydratase BASH2_03518 ENOG4105N14 lysine exporter protein LysE YggA BASH2_03520 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BASH2_03521 ENOG4105C1G acyl-Coa dehydrogenase BASH2_03522 ENOG4105CR4 methylisocitrate lyase BASH2_03523 ENOG4105DXD 2-methylcitrate dehydratase BASH2_03525 ENOG4105W8X HesB YadR YfhF-family protein BASH2_03526 ENOG4105CZM Major Facilitator BASH2_03527 ENOG4105BZ4 penicillin-binding protein BASH2_03535 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BASH2_03553 ENOG4108IBT Inherit from COG: transposase BASH2_03556 ENOG4105SZ6 Thioredoxin BASH2_03558 ENOG410841Q phosphoesterase PA-phosphatase related protein BASH2_03559 ENOG4108N23 SpoOM-related protein BASH2_03566 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BASH2_03567 ENOG4108JUB Transcriptional regulator BASH2_03568 ENOG4108TSC N-acetyltransferase BASH2_03569 ENOG4107S4Y M20 DapE family protein YgeY BASH2_03572 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BASH2_03577 ENOG4105C37 (CBS) domain BASH2_03585 ENOG4105E90 ABC transporter BASH2_03586 ENOG4108IJ8 ABC transporter BASH2_03593 ENOG4105CMG Carbohydrate kinase BASH2_03594 ENOG4105CMG Carbohydrate kinase BASH2_03602 ENOG4106KNT transcriptional regulator BASH2_03604 ENOG4105WH1 Two component transcriptional regulator luxr family BASH2_03605 ENOG4105BZU Histidine kinase BASH2_03606 ENOG4105D8X mechanosensitive ion channel BASH2_03613 ENOG4105F0I Aminotransferase BASH2_03614 ENOG4108MES Periplasmic binding protein BASH2_03617 ENOG4105CAQ asparagine synthetase BASH2_03618 ENOG4107Y70 Heat shock protein BASH2_03619 ENOG4108KF3 Electron transport protein SCO1 SenC BASH2_03620 ENOG4105E8R UPF0173 metal-dependent hydrolase BASH2_03621 ENOG4108RCR degv family BASH2_03623 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BASH2_03625 ENOG4108UT2 hemolysin iii BASH2_03626 ENOG4105E9Q Acyl-transferase BASH2_03627 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BASH2_03628 ENOG4107RVG penicillin-binding protein BASH2_03631 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BASH2_03635 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BASH2_03641 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BASH2_03643 ENOG4105KD7 acetyltransferase BASH2_03646 ENOG4105C0A alcohol dehydrogenase BASH2_03647 ENOG4105CY2 Citrate transporter BASH2_03648 ENOG4107XGZ Hydrolase BASH2_03652 ENOG4105C8J )-transporter BASH2_03655 ENOG41062D9 Histidine kinase BASH2_03656 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_03657 ENOG4107QPK )-transporter BASH2_03658 ENOG4105BZW Glycerate kinase BASH2_03678 ENOG4105EC2 ftsk spoIIIe BASH2_03682 ENOG4105C5S asparaginyl-tRNA synthetase BASH2_03683 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BASH2_03686 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BASH2_03691 ENOG4105C75 arginyL-tRNA synthetase BASH2_03692 ENOG4107YX5 Pfam:DUF548 BASH2_03696 ENOG41061H0 Monooxygenase BASH2_03699 ENOG4108UUM single-stranded DNA-binding protein BASH2_03702 ENOG4105C5H ABC transporter BASH2_03706 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BASH2_03709 ENOG4105MCT stage V sporulation protein S BASH2_03716 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BASH2_03717 ENOG4108IFG nitrite reductase, (NAD(P)H) BASH2_03718 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BASH2_03719 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BASH2_03720 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BASH2_03721 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BASH2_03727 ENOG4108ZAF Molybdopterin BASH2_03728 ENOG4105CVM Molybdenum cofactor synthesis domain protein BASH2_03729 ENOG4105D06 uba thif-type nad fad binding protein BASH2_03730 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BASH2_03731 ENOG4107V6Q Cyclic nucleotide-binding domain BASH2_03735 ENOG4105R3A Nitrate reductase BASH2_03736 ENOG4108IUE nitrate reductase beta subunit BASH2_03740 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BASH2_03744 ENOG4108V06 Glutathione peroxidase BASH2_03749 ENOG4105EMN RNA polymerase sigma factor BASH2_03750 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BASH2_03752 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BASH2_03753 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BASH2_03757 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BASH2_03762 ENOG4105KBJ sporulation protein ytfj BASH2_03770 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BASH2_03777 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BASH2_03778 ENOG4108JYZ YitT family BASH2_03779 ENOG41087PP glycosyltransferase MGT family BASH2_03782 ENOG4107RBS Methyltransferase BASH2_03783 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BASH2_03785 ENOG4108X4Q Hydrolase BASH2_03790 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BASH2_03792 ENOG4108VXD carboxy-peptidase BASH2_03794 ENOG4108ZRV stage ii sporulation protein p BASH2_03796 ENOG4108Z7R Chaperone CsaA BASH2_03800 ENOG4105C37 (CBS) domain BASH2_03801 ENOG4105SXS Protein of unknown function (DUF456) BASH2_03807 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BASH2_03808 ENOG4108S4H thioesterase Superfamily protein BASH2_03810 ENOG4108PJD permease BASH2_03813 ENOG4107T5V SNARE associated Golgi BASH2_03817 ENOG4105CVJ phosphoglycerate mutase BASH2_03822 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BASH2_03824 ENOG4105K4T epimerase BASH2_03825 ENOG4105DSE periplasmic solute binding protein BASH2_03832 ENOG4105CKI cobalamin synthesis protein BASH2_03833 ENOG4107QM2 Aldo Keto reductase BASH2_03838 ENOG4105DEN Luciferase family BASH2_03841 ENOG4108WPJ Ferritin-like domain BASH2_03842 ENOG4108K88 Membrane BASH2_03845 ENOG4105C8Q Methyl-accepting chemotaxis BASH2_03850 ENOG4107XZQ multidrug resistance protein BASH2_03851 ENOG4107SET aldo keto reductase BASH2_03852 ENOG4105YVS arsR family transcriptional regulator BASH2_03854 ENOG4105KRN Transcriptional regulator, abrb family BASH2_03866 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BASH2_03868 ENOG4107RCC Major Facilitator Superfamily BASH2_03870 ENOG4105YWU small acid-soluble spore protein BASH2_03871 ENOG4108WBH protein TIM barrel BASH2_03875 ENOG4105CEY Amp-dependent synthetase and ligase BASH2_03876 ENOG4105DUU IucA IucC family protein BASH2_03878 ENOG4105VRR gCN5-related N-acetyltransferase BASH2_03879 ENOG4105KT7 mgtC SapB transporter BASH2_03881 ENOG4107VMI polysaccharide deacetylase BASH2_03882 ENOG4105BZU Histidine kinase BASH2_03883 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_03885 ENOG4108KGH TRANSCRIPTIONal BASH2_03890 ENOG4105D6E homoserine dehydrogenase BASH2_03895 ENOG4108ZJ4 polysaccharide deacetylase BASH2_03896 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BASH2_03900 ENOG4105BZU Histidine kinase BASH2_03901 ENOG4105EFI regulatoR BASH2_03902 ENOG4105BZ1 (ABC) transporter BASH2_03903 ENOG4105BZ1 (ABC) transporter BASH2_03911 ENOG4108JJ8 (ABC) transporter BASH2_03912 ENOG4108JJ9 ABC, transporter BASH2_03913 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BASH2_03914 ENOG4105C4M (Ubiquinol oxidase) subunit I BASH2_03916 ENOG4105YGB Transcriptional regulator BASH2_03918 ENOG4105MDS 4-oxalocrotonate tautomerase BASH2_03920 ENOG4105SKE transcriptional Regulator LysR family BASH2_03922 ENOG4105C32 Amino acid ABC transporter (Permease) BASH2_03923 ENOG4108IV0 ABC, transporter BASH2_03924 ENOG4105C0Z ABC transporter BASH2_03926 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BASH2_03927 ENOG4108Z7G MaoC domain protein dehydratase BASH2_03931 ENOG4105CKI cobalamin synthesis protein BASH2_03933 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BASH2_03934 ENOG4106F5Q Membrane BASH2_03935 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BASH2_03937 ENOG4108TVJ Nitroreductase BASH2_03938 ENOG4107ZXU DSBA oxidoreductase BASH2_03939 ENOG4108Z40 Transcriptional regulator BASH2_03940 ENOG4105GZI Transcriptional regulator BASH2_03941 ENOG4107RT3 EamA-like transporter family BASH2_03943 ENOG4105KTB nuclear export factor GLE1 BASH2_03944 ENOG4108T5E Copper resistance protein BASH2_03954 ENOG4107STQ Multicopper oxidase BASH2_03955 ENOG4107RAQ aminopeptidase BASH2_03962 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BASH2_03963 ENOG4105D9N nucleoside BASH2_03965 ENOG4107RHR regulatoR BASH2_03970 ENOG4105C0X amino acid BASH2_03971 ENOG4105C0X amino acid BASH2_03972 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BASH2_03974 ENOG4105C72 UPF0176 protein BASH2_03975 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BASH2_03980 ENOG41068WN BASH2_03989 ENOG4108J59 Extracellular solute-binding protein, family 5 BASH2_03991 ENOG4105F6J Alpha beta hydrolase fold BASH2_03995 ENOG4105CYC Transferase BASH2_03996 ENOG4105DY9 regulatoR BASH2_03998 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BASH2_03999 ENOG4105C6X Major Facilitator BASH2_04003 ENOG4105C7B Threonine dehydratase BASH2_04005 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BASH2_04006 ENOG4108ZP8 Acetolactate synthase small subunit BASH2_04007 ENOG4105C7K acetolactate synthase BASH2_04008 ENOG4105CM2 brancheD-chain amino acid aminotransferase BASH2_04009 ENOG4105CHR reductase BASH2_04010 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BASH2_04013 ENOG4106KE4 Dehydrogenase BASH2_04016 ENOG4105H67 Protein of unknown function (DUF421) BASH2_04017 ENOG4105X5K response regulator receiver protein BASH2_04019 ENOG4105C8J )-transporter BASH2_04023 ENOG4105C6T cysteine synthase BASH2_04024 ENOG4105EU0 Major facilitator Superfamily BASH2_04027 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BASH2_04030 ENOG4105DXI Major Facilitator superfamily BASH2_04031 ENOG4105DXI Major Facilitator superfamily BASH2_04032 ENOG4105CSR polyphosphate kinase 2 BASH2_04040 ENOG4105FVX BASH2_04053 ENOG4105C6K Malic enzyme BASH2_04054 ENOG4108IJ0 Aspartate ammonia-lyase BASH2_04056 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BASH2_04060 ENOG4105CJ1 ABC, transporter BASH2_04067 ENOG4106BRA Membrane BASH2_04074 ENOG4107QIV Cytochrome c biogenesis protein BASH2_04078 ENOG4105EC3 peptidase S51, dipeptidase E BASH2_04080 ENOG4107QJQ Mate efflux family protein BASH2_04081 ENOG4107QJQ Mate efflux family protein BASH2_04085 ENOG4105C9Q fumarate hydratase class II BASH2_04086 ENOG4105DFD Na H antiporter BASH2_04089 ENOG4108PJD permease BASH2_04090 ENOG4105CKI cobalamin synthesis protein BASH2_04091 ENOG4108UZ3 Transporter BASH2_04092 ENOG4105DRR Transcriptional regulator, GntR family BASH2_04094 ENOG4105PGM cation diffusion facilitator family transporter BASH2_04098 ENOG4105CAQ asparagine synthetase BASH2_04105 ENOG4105CVJ phosphoglycerate mutase BASH2_04112 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BASH2_04113 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BASH2_04114 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BASH2_04115 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BASH2_04116 ENOG4105DUM transcriptional regulator, lysR family BASH2_04121 ENOG4105KAC Antibiotic biosynthesis monooxygenase BASH2_04124 ENOG4108RZE Tetr family transcriptional regulator BASH2_04129 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BASH2_04130 ENOG4105KTQ flagellar basal-body rod protein BASH2_04131 ENOG4105FZW flagellar biosynthesis regulator FlhF BASH2_04133 ENOG4105D7B Flagellar biosynthesis protein flha BASH2_04134 ENOG4105D00 flagellar biosynthetic protein flhB BASH2_04136 ENOG4105VS8 Flagellar biosynthetic protein fliq BASH2_04137 ENOG4105CN7 Flagellar biosynthetic protein FliP BASH2_04139 ENOG4105DD5 Flagellar motor switch protein BASH2_04141 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BASH2_04143 ENOG4105E4C Lytic transglycosylase catalytic BASH2_04144 ENOG4105I03 Flagellin BASH2_04147 ENOG4107TVC Glycosyl transferase, family 2 BASH2_04155 ENOG4105K64 Glycosyl transferase, family 2 BASH2_04157 ENOG4107R88 Chemotaxis protein (CheV) BASH2_04158 ENOG4107R88 Chemotaxis protein (CheV) BASH2_04162 ENOG4105BZE flagellar hook protein, FlgE BASH2_04170 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BASH2_04172 ENOG4107U2N Flagellar M-ring protein BASH2_04173 ENOG41075Z6 flagellar hook-basal body complex protein fliE BASH2_04174 ENOG4108ZC9 flagellar basal-body rod protein flgc BASH2_04175 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BASH2_04180 ENOG4105DTJ flagellar hook-associated protein BASH2_04181 ENOG4105E1Q flagellar hook-associated protein BASH2_04185 ENOG4105BZU Histidine kinase BASH2_04188 ENOG4105DD5 Flagellar motor switch protein BASH2_04189 ENOG4105CBS Chea signal transduction histidine kinase BASH2_04190 ENOG4105CBS Chea signal transduction histidine kinase BASH2_04191 ENOG4107YTP response regulator receiver protein BASH2_04192 ENOG4105ER2 Ompa motb domain protein BASH2_04193 ENOG4107R0U MotA TolQ exbB proton channel BASH2_04195 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BASH2_04205 ENOG41080C8 DUF218 domain BASH2_04207 ENOG4105H67 Protein of unknown function (DUF421) BASH2_04209 ENOG4108Z5V transcriptional regulator, merr family BASH2_04210 ENOG4105CN5 Metallo-Beta-Lactamase BASH2_04211 ENOG4107RWR Sodium hydrogen exchanger BASH2_04214 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BASH2_04227 ENOG41081VK Ribonuclease BASH2_04231 ENOG4108SZE gCN5-related N-acetyltransferase BASH2_04251 ENOG4105CPK Glycosyl transferase (Group 1 BASH2_04263 ENOG4106032 Glutathionylspermidine synthase BASH2_04266 ENOG4105KHC sulfurtransferase BASH2_04268 ENOG4108W0I acetyltransferase BASH2_04269 ENOG410890F Dynamin family BASH2_04271 ENOG4105DHF Membrane BASH2_04272 ENOG4105C2W permease BASH2_04274 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BASH2_04278 ENOG4105CTD carboxy-peptidase BASH2_04279 ENOG4105DVT helicase BASH2_04281 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BASH2_04292 ENOG4105BZ4 penicillin-binding protein BASH2_04294 ENOG4105CSM endonuclease III BASH2_04298 ENOG4105YAC BASH2_04299 ENOG4105DVT helicase BASH2_04306 ENOG4105CPK Glycosyl transferase (Group 1 BASH2_04307 ENOG4105FJR Lmbe family BASH2_04310 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BASH2_04311 ENOG4108JYZ YitT family BASH2_04318 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BASH2_04319 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BASH2_04320 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BASH2_04323 ENOG41068YB TPR repeat-containing protein BASH2_04324 ENOG4105CIH Imidazole acetol-phosphate transaminase BASH2_04328 ENOG4105EAH synthase BASH2_04330 ENOG4105XXQ heptaprenyl diphosphate synthase component I BASH2_04333 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BASH2_04339 ENOG41065D1 BASH2_04340 ENOG4105S2F BASH2_04346 ENOG4105HDK L-asparaginase BASH2_04347 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BASH2_04352 ENOG4108S6Z Negative regulator of genetic competence BASH2_04353 ENOG4107X2D transcriptional regulator, merr family BASH2_04354 ENOG4107RGJ metallophosphoesterase BASH2_04355 ENOG4107RGJ metallophosphoesterase BASH2_04357 ENOG4105I7S Abortive infection protein BASH2_04358 ENOG4105C9U ATP-dependent DNA helicase RecQ BASH2_04359 ENOG4105T7X BASH2_04361 ENOG4108SAX Membrane BASH2_04362 ENOG4108SAX Membrane BASH2_04365 ENOG4108WBT adenosyltransferase BASH2_04366 ENOG4105BZU Histidine kinase BASH2_04367 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_04368 ENOG4105CRE cytochrome C BASH2_04369 ENOG4107TWT Cytochrome c biogenesis protein BASH2_04371 ENOG4105FE9 pseudouridine synthase BASH2_04373 ENOG4108JIC nucleoside recognition domain protein BASH2_04374 ENOG4105DZ1 carboxypeptidase BASH2_04375 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BASH2_04382 ENOG4105BZU Histidine kinase BASH2_04385 ENOG4105I3N Conserved Protein BASH2_04386 ENOG4105BZU Histidine kinase BASH2_04389 ENOG4105BZ4 penicillin-binding protein BASH2_04390 ENOG4107GRR phosphate transport regulator BASH2_04391 ENOG4105CJ3 phosphate transporter BASH2_04395 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BASH2_04400 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BASH2_04403 ENOG4105WH1 Two component transcriptional regulator luxr family BASH2_04404 ENOG4105ENE Histidine kinase BASH2_04408 ENOG4105DFD Na H antiporter BASH2_04412 ENOG4105C8J )-transporter BASH2_04413 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BASH2_04414 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BASH2_04415 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BASH2_04417 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BASH2_04418 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BASH2_04422 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BASH2_04424 ENOG4105E0M Sulfatase BASH2_04425 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BASH2_04428 ENOG4107RVV histidinol phosphate phosphatase, hisj family BASH2_04435 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BASH2_04440 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BASH2_04442 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BASH2_04443 ENOG4108ZP8 Acetolactate synthase small subunit BASH2_04444 ENOG4105C7K acetolactate synthase BASH2_04445 ENOG4105CM2 brancheD-chain amino acid aminotransferase BASH2_04449 ENOG4105KBJ sporulation protein ytfj BASH2_04450 ENOG41063Y9 BASH2_04451 ENOG4105CZN Potassium uptake protein BASH2_04457 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BASH2_04458 ENOG4107QMU Mate efflux family protein BASH2_04466 ENOG4105NQC Flavodoxin BASH2_04471 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BASH2_04473 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BASH2_04474 ENOG4105EA8 2-Nitropropane dioxygenase BASH2_04475 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BASH2_04483 ENOG4105CJ1 ABC, transporter BASH2_04485 ENOG4105CZV ABC transporter BASH2_04486 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BASH2_04487 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BASH2_04488 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BASH2_04490 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BASH2_04491 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BASH2_04499 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BASH2_04500 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BASH2_04502 ENOG4105BZU Histidine kinase BASH2_04504 ENOG4106DF1 BASH2_04506 ENOG41090MY MarR family Transcriptional regulator BASH2_04507 ENOG4105BZU Histidine kinase BASH2_04509 ENOG4105PXI polysaccharide deacetylase BASH2_04511 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BASH2_04512 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BASH2_04517 ENOG4105E98 transcriptional regulator DeoR family BASH2_04520 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BASH2_04521 ENOG4107RCV ABC transporter, permease BASH2_04523 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BASH2_04525 ENOG4105C4Y ABC transporter BASH2_04529 ENOG4105MWK D-amino acid dehydrogenase, small subunit BASH2_04531 ENOG4105CHR reductase BASH2_04536 ENOG4108Z7G MaoC domain protein dehydratase BASH2_04537 ENOG410681C small acid-soluble spore protein BASH2_04538 ENOG4105CZN Potassium uptake protein BASH2_04539 ENOG4107TS3 membrane protein, TerC BASH2_04540 ENOG4108QTI )-transporter BASH2_04543 ENOG4106A3R peptidase BASH2_04547 ENOG4105JXH GntR family transcriptional regulator BASH2_04548 ENOG4105BZU Histidine kinase BASH2_04549 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_04552 ENOG4105CQB FAD linked oxidase domain protein BASH2_04553 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BASH2_04554 ENOG4105K4I Scp-like extracellular BASH2_04556 ENOG4108YBP pseudouridine synthase BASH2_04558 ENOG4105EYF MMPL domain protein BASH2_04560 ENOG4107RUE extracellular solute-binding protein family 1 BASH2_04561 ENOG4105D38 putrescine abc transporter BASH2_04562 ENOG4105F38 ABC transporter, permease BASH2_04563 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BASH2_04564 ENOG4105C26 Dehydrogenase BASH2_04570 ENOG4105VFR signal peptidase BASH2_04571 ENOG4105DZ1 carboxypeptidase BASH2_04574 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BASH2_04583 ENOG4105VZ8 Transcriptional regulator BASH2_04585 ENOG4105C7S Dehydrogenase BASH2_04604 ENOG4105DDQ anthranilate synthase BASH2_04605 ENOG4105CRQ synthase (Component I) BASH2_04606 ENOG4105CK7 Sodium proline symporter BASH2_04612 ENOG4108WVJ 2'-5' rna ligase BASH2_04622 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BASH2_04624 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BASH2_04625 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BASH2_04629 ENOG4107TVC Glycosyl transferase, family 2 BASH2_04636 ENOG4105K64 Glycosyl transferase, family 2 BASH2_04638 ENOG4105CNI cell division protein FtsW BASH2_04642 ENOG4105EMS pseudouridine synthase BASH2_04643 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BASH2_04646 ENOG4105MIX Adenylate cyclase BASH2_04647 ENOG4108Z18 K06886 hemoglobin BASH2_04649 ENOG4105DPN Oligoendopeptidase f BASH2_04651 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BASH2_04653 ENOG4108ZCF integral membrane protein BASH2_04658 ENOG4105UQX Mate efflux family protein BASH2_04659 ENOG4108JQ7 (ABC) transporter BASH2_04661 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BASH2_04662 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BASH2_04665 ENOG4105C31 Tryptophanyl-tRNA synthetase BASH2_04668 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BASH2_04669 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BASH2_04676 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BASH2_04678 ENOG4108KP7 hydrolase BASH2_04680 ENOG41073B9 BASH2_04681 ENOG4107AYK membrAne BASH2_04683 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BASH2_04685 ENOG4105QNR S1 RNA binding domain protein BASH2_04690 ENOG4105BZU Histidine kinase BASH2_04691 ENOG4105CH6 catalase BASH2_04692 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BASH2_04693 ENOG4105CAQ asparagine synthetase BASH2_04697 ENOG4105ERH Fumarylacetoacetate hydrolase BASH2_04706 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BASH2_04707 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BASH2_04710 ENOG4105XVF Competence transcription factor BASH2_04713 ENOG4105VEQ Cold shock protein BASH2_04716 ENOG4107QP3 malate synthase g BASH2_04717 ENOG4105ZU5 s-layer protein BASH2_04721 ENOG4105C8Q Methyl-accepting chemotaxis BASH2_04722 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BASH2_04726 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_04730 ENOG41086D8 Transcriptional regulator BASH2_04731 ENOG4108AEY RNA polymerase sigma factor BASH2_04733 ENOG4107TVP HD domain protein BASH2_04734 ENOG4107RN3 metallophosphoesterase BASH2_04735 ENOG4105ENX hydrolase BASH2_04742 ENOG4105CNA YD repeat protein BASH2_04749 ENOG4105CEY Amp-dependent synthetase and ligase BASH2_04751 ENOG4105DF9 Lipoate-protein, ligase BASH2_04752 ENOG4108RQ5 Beta-lactamase domain-containing protein BASH2_04757 ENOG4105ECB domain protein BASH2_04760 ENOG4105NA0 Transcriptional regulator BASH2_04766 ENOG4105C1Q protoporphyrinogen oxidase BASH2_04768 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BASH2_04769 ENOG4105BZ4 penicillin-binding protein BASH2_04770 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BASH2_04771 ENOG4105CKV Membrane BASH2_04772 ENOG410905X membrane-flanked domain protein BASH2_04781 ENOG4105CKV Membrane BASH2_04783 ENOG410905X membrane-flanked domain protein BASH2_04790 ENOG4105K59 histidine triad (HIT) protein BASH2_04794 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BASH2_04795 ENOG4105EEM helicase BASH2_04797 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_04798 ENOG4105C57 major facilitator superfamily BASH2_04803 ENOG4105EMN RNA polymerase sigma factor BASH2_04805 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BASH2_04808 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BASH2_04812 ENOG4108MUZ hydrolase BASH2_04817 ENOG4105EQ0 Major Facilitator superfamily BASH2_04818 ENOG4108IND Tetr family transcriptional regulator BASH2_04821 ENOG4105D7V transposase BASH2_04822 ENOG4106D4I domain protein BASH2_04823 ENOG4107VRP DNA repair exonuclease BASH2_04829 ENOG4105K8R UPF0145 protein BASH2_04834 ENOG4105BZU Histidine kinase BASH2_04835 ENOG4105BZU Histidine kinase BASH2_04836 ENOG4108MJI response regulator BASH2_04838 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BASH2_04840 ENOG4105WN5 stage II sporulation protein BASH2_04852 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BASH2_04859 ENOG410847I Transcriptional regulator, BadM Rrf2 family BASH2_04860 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BASH2_04861 ENOG4105CMT Dihydroxyacetone kinase BASH2_04863 ENOG4105CMT Dihydroxyacetone kinase BASH2_04867 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BASH2_04871 ENOG4108IG5 Transcriptional regulator BASH2_04872 ENOG4107P5I polyketide synthase BASH2_04882 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_04891 ENOG4105CDU Replicative dna helicase BASH2_04900 ENOG4108MRH transcriptional regulatory protein BASH2_04902 ENOG4105CSH Transporter BASH2_04909 ENOG4108JQ7 (ABC) transporter BASH2_04912 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BASH2_04921 ENOG4105CTU Proline racemase BASH2_04925 ENOG4105DER m42 family BASH2_04928 ENOG4105CGU Enoyl-CoA hydratase BASH2_04933 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BASH2_04934 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BASH2_04937 ENOG4106AKK s-layer domain-containing protein BASH2_04945 ENOG4105CHH sulfate transporter BASH2_04948 ENOG4105D4P Coproporphyrinogen iii oxidase BASH2_04950 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BASH2_04955 ENOG4107FQX Alpha-acetolactate decarboxylase BASH2_04963 ENOG410839P BASH2_04965 ENOG4105CDA abc transporter atp-binding protein BASH2_04966 ENOG4105DRP amino acid AbC transporter BASH2_04968 ENOG4105BZ1 (ABC) transporter BASH2_04969 ENOG4105BZ1 (ABC) transporter BASH2_04970 ENOG4105BZ1 (ABC) transporter BASH2_04971 ENOG4105C26 Dehydrogenase BASH2_04973 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BASH2_04974 ENOG4105D5Q Arginine ornithine antiporter BASH2_04976 ENOG4105CH6 catalase BASH2_04977 ENOG4107RKG DJ-1/PfpI family BASH2_04980 ENOG4105E5W Transporter BASH2_04981 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BASH2_04982 ENOG4105NF4 modulator of drug activity BASH2_04987 ENOG4105KPY Small multidrug resistance protein BASH2_04988 ENOG4105KPY Small multidrug resistance protein BASH2_04990 ENOG4108YXU transcriptional regulator AsnC family BASH2_04991 ENOG4108PCN EamA-like transporter family BASH2_04998 ENOG4106KNT transcriptional regulator BASH2_05000 ENOG4107RWR Sodium hydrogen exchanger BASH2_05001 ENOG4105CUB amino acid BASH2_05009 ENOG4107T5V SNARE associated Golgi BASH2_05016 ENOG4105WEF catalase BASH2_05022 ENOG4105C19 ABC transporter BASH2_05023 ENOG4107RBB ABC transporter, permease BASH2_05024 ENOG41069ER domain protein BASH2_05028 ENOG4105VZJ PTS System BASH2_05029 ENOG4105VCP PTS System BASH2_05030 ENOG4105EMD TRANSCRIPTIONal BASH2_05035 ENOG4108KGH TRANSCRIPTIONal BASH2_05037 ENOG41087NI Sulfite exporter TauE/SafE BASH2_05038 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BASH2_05040 ENOG41085GJ domain protein BASH2_05041 ENOG4105VFE sira family BASH2_05042 ENOG4107TPS domain protein BASH2_05043 ENOG4105VFE sira family BASH2_05044 ENOG4105XTG Pfam:DUF156 BASH2_05045 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BASH2_05051 ENOG4105ED1 spovr family BASH2_05052 ENOG4107Y03 Nitroreductase BASH2_05057 ENOG4108B31 Spore germination protein BASH2_05064 ENOG4105C5Y PTS System BASH2_05069 ENOG4105C7N Xanthine uracil vitamin C permease BASH2_05072 ENOG4108INS Transcriptional regulator BASH2_05081 ENOG4105DWF phosphomethylpyrimidine kinase BASH2_05082 ENOG4105D06 uba thif-type nad fad binding protein BASH2_05085 ENOG41080HI glycine oxidase BASH2_05086 ENOG4108VEU Thiamine monophosphate synthase BASH2_05088 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BASH2_05090 ENOG4105ETU transcriptional activator (TenA BASH2_05094 ENOG41080XQ Signal transduction protein with cbs domains BASH2_05098 ENOG4105E2Z phosphate ABC transporter (Permease BASH2_05099 ENOG4105C8U phosphate abc transporter BASH2_05100 ENOG4105CVA phosphate BASH2_05101 ENOG4105CE1 Ferrous iron transport protein b BASH2_05102 ENOG4105CE1 Ferrous iron transport protein b BASH2_05103 ENOG4105CE1 Ferrous iron transport protein b BASH2_05104 ENOG4108NHD germination protein BASH2_05107 ENOG4105E1V na solute symporter BASH2_05108 ENOG4106CAD Protein of unknown function (DUF3311) BASH2_05111 ENOG4105E2S oxidase) subunit II BASH2_05112 ENOG4105BZ9 Cytochrome C oxidase, subunit I BASH2_05119 ENOG4105C7N Xanthine uracil vitamin C permease BASH2_05120 ENOG4105C85 amino acid BASH2_05125 ENOG4105DUX Transporter BASH2_05127 ENOG4107D63 BASH2_05128 ENOG4105VZ8 Transcriptional regulator BASH2_05129 ENOG41069ER domain protein BASH2_05130 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BASH2_05131 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BASH2_05143 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BASH2_05144 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BASH2_05145 ENOG4105CNN ABC, transporter BASH2_05146 ENOG4105C2J ABC transporter BASH2_05148 ENOG4108RVA ribokinase BASH2_05149 ENOG4105ETE Transcriptional regulator (LacI family BASH2_05150 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_05151 ENOG4105C0R drug resistance transporter emrb qaca subfamily BASH2_05152 ENOG41067TZ transcriptional regulator, MarR family BASH2_05153 ENOG4105CXY transporter BASH2_05155 ENOG4108JQ7 (ABC) transporter BASH2_05156 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BASH2_05158 ENOG4105DEF Extracellular solute-binding protein, family 5 BASH2_05160 ENOG41068KF Universal stress protein BASH2_05161 ENOG4105CHH sulfate transporter BASH2_05165 ENOG4105BZU Histidine kinase BASH2_05166 ENOG4105NAE bifunctional deaminase-reductase domain protein BASH2_05167 ENOG4105D29 Helix-turn-helix type 11 domain protein BASH2_05172 ENOG4108IQI permease BASH2_05173 ENOG4105DRP amino acid AbC transporter BASH2_05174 ENOG4105EAD ABC transporter BASH2_05175 ENOG4105CT1 (ABC) transporter BASH2_05176 ENOG4105CDA abc transporter atp-binding protein BASH2_05177 ENOG4105BZG amino acid carrier protein BASH2_05178 ENOG4105CRN Aminoglycoside phosphotransferase BASH2_05180 ENOG4105E1K spore germination protein BASH2_05183 ENOG4105CG3 alpha amylase, catalytic region BASH2_05184 ENOG4105C5Y PTS System BASH2_05185 ENOG4107414 GntR family transcriptional regulator BASH2_05186 ENOG4105D5Q Arginine ornithine antiporter BASH2_05187 ENOG4105BZU Histidine kinase BASH2_05190 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BASH2_05191 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BASH2_05192 ENOG4107T89 von Willebrand factor, type A BASH2_05194 ENOG4105EXW epimerase dehydratase BASH2_05196 ENOG4105DMQ Methyltransferase BASH2_05197 ENOG4105E0A ABC, transporter BASH2_05198 ENOG4108IHU transport system permease protein BASH2_05199 ENOG4105DQ5 transport system permease protein BASH2_05200 ENOG4108MES Periplasmic binding protein BASH2_05201 ENOG4105DUX Transporter BASH2_05204 ENOG4105DAA L-lactate BASH2_05205 ENOG4108IJ0 Aspartate ammonia-lyase BASH2_05206 ENOG4105C37 (CBS) domain BASH2_05207 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BASH2_05208 ENOG4105D9N nucleoside BASH2_05209 ENOG4108KGH TRANSCRIPTIONal BASH2_05210 ENOG41073R8 VanW family BASH2_05218 ENOG4105DAP Nicotinate phosphoribosyltransferase BASH2_05219 ENOG4105C59 p-type ATPase BASH2_05221 ENOG4105CUB amino acid BASH2_05227 ENOG4108JB9 formate dehydrogenase BASH2_05228 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BASH2_05229 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BASH2_05231 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BASH2_05232 ENOG4105BZU Histidine kinase BASH2_05234 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BASH2_05235 ENOG4108UZ3 Transporter BASH2_05237 ENOG4105C6K Malic enzyme BASH2_05239 ENOG4108MRH transcriptional regulatory protein BASH2_05244 ENOG4105US7 Histidine kinase BASH2_05245 ENOG4108STX response regulator BASH2_05246 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BASH2_05247 ENOG4105BZ7 extracellular solute-binding protein family 1 BASH2_05248 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BASH2_05249 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BASH2_05250 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BASH2_05251 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BASH2_05255 ENOG4105D4T Citrate transporter BASH2_05256 ENOG4108MRH transcriptional regulatory protein BASH2_05257 ENOG4108MRH transcriptional regulatory protein BASH2_05258 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BASH2_05260 ENOG4105DZ6 Band 7 protein BASH2_05263 ENOG4105C94 Transporter BASH2_05267 ENOG4105CYN Serine protein kinase BASH2_05269 ENOG4105BZU Histidine kinase BASH2_05270 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BASH2_05272 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BASH2_05273 ENOG4107ZQN disulfide bond BASH2_05274 ENOG4108JQC penicillin-binding protein 1A BASH2_05281 ENOG4105G5W regulator Fur family BASH2_05282 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BASH2_05286 ENOG4108IUW ABC transporter BASH2_05288 ENOG4105CBC glutamate synthase BASH2_05289 ENOG4107NBY Membrane BASH2_05290 ENOG4105BZ1 (ABC) transporter BASH2_05294 ENOG4106BXE BASH2_05295 ENOG4105CEN a g-specific adenine glycosylase BASH2_05296 ENOG41067AE Membrane-bound metal-dependent hydrolase BASH2_05302 ENOG4105ECP epimerase BASH2_05303 ENOG4105CI2 imidazolone-5-propionate hydrolase BASH2_05307 ENOG4105F1A Pyruvate formate-lyase BASH2_05310 ENOG4105C3I Nad-dependent epimerase dehydratase BASH2_05311 ENOG4107QQG Dehydrogenase BASH2_05313 ENOG4105CKK Glycosyl transferase, family 2 BASH2_05316 ENOG4108A04 Beta-lactamase BASH2_05319 ENOG4105CSV Glutaminase BASH2_05325 ENOG4108IQI permease BASH2_05328 ENOG4108JUB Transcriptional regulator BASH2_05329 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BASH2_05384 ENOG4105VTR Integrase BASH2_05385 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BASH2_05393 ENOG4105UPD Calcium Proton BASH2_05394 ENOG410606W general stress protein BASH2_05397 ENOG4107ZTW SNARE associated Golgi BASH2_05400 ENOG4105C3F Signal peptidase i BASH2_05402 ENOG4108IPJ Membrane BASH2_05403 ENOG4105C59 p-type ATPase BASH2_05404 ENOG4107U9T Pfam:Ribonuclease_BN BASH2_05406 ENOG4105KJF protein tyrosine phosphatase BASH2_05410 ENOG4108TTB tellurium resistance protein BASH2_05411 ENOG4107TS3 membrane protein, TerC BASH2_05412 ENOG4106FN3 tellurium resistance protein BASH2_05413 ENOG4106FN3 tellurium resistance protein BASH2_05414 ENOG4108N0M stress protein BASH2_05417 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BASH2_05420 ENOG4105DEU major facilitator superfamily BASH2_05424 ENOG41062JF Transcriptional regulator BASH2_05429 ENOG4105C5H ABC transporter BASH2_05432 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BASH2_05435 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BASH2_05441 ENOG4105CI1 PTS System BASH2_05443 ENOG4105C8Q Methyl-accepting chemotaxis BASH2_05444 ENOG4105C8Q Methyl-accepting chemotaxis BASH2_05446 ENOG4105EAB amino acid AbC transporter BASH2_05448 ENOG4105E5Q amino acid AbC transporter BASH2_05451 ENOG4105D2S major facilitator superfamily BASH2_05452 ENOG410756H nucleotidyltransferase BASH2_05456 ENOG4105BZU Histidine kinase BASH2_05462 ENOG4106UIA BASH2_05463 ENOG4106UIA BASH2_05467 ENOG4108V5C ABC transporter BASH2_05468 ENOG4105DQ5 transport system permease protein BASH2_05469 ENOG4105EHG Permease protein BASH2_05470 ENOG4107W7X Aldolase BASH2_05472 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BASH2_05473 ENOG4105D3R alkyl hydroperoxide reductase BASH2_05478 ENOG4105DFD Na H antiporter BASH2_05480 ENOG4105DTQ mandelate racemase muconate lactonizing BASH2_05483 ENOG4108W15 Protein of unknown function (DUF1456) BASH2_05486 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BASH2_05487 ENOG4105D9N nucleoside BASH2_05491 ENOG4105KPY Small multidrug resistance protein BASH2_05492 ENOG4105C26 Dehydrogenase BASH2_05494 ENOG4108JPW Aminotransferase BASH2_05495 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BASH2_05496 ENOG4105CBD Diacylglycerol kinase BASH2_05501 ENOG410834F Transcriptional regulator BASH2_05502 ENOG4105D0U Arsenite-activated ATPase (ArsA) BASH2_05505 ENOG4105D01 (LipO)protein BASH2_05506 ENOG4108UMI ABC transporter, permease BASH2_05507 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BASH2_05508 ENOG4108W2Y isochorismatase BASH2_05514 ENOG4105C4R Atp-dependent dna helicase BASH2_05519 ENOG4105C12 Phosphoribosylglycinamide synthetase BASH2_05521 ENOG4108V3E phosphoribosylglycinamide formyltransferase BASH2_05526 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BASH2_05528 ENOG4105C83 adenylosuccinate lyase BASH2_05529 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BASH2_05530 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BASH2_05532 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BASH2_05536 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BASH2_05539 ENOG4108SHN Glycosyl transferase, family 2 BASH2_05544 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BASH2_05549 ENOG4105BZU Histidine kinase BASH2_05551 ENOG4105C7N Xanthine uracil vitamin C permease BASH2_05555 ENOG4108TYN CAAX amino terminal protease family protein BASH2_05557 ENOG4105C5H ABC transporter BASH2_05558 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BASH2_05559 ENOG410801F ribosomal-protein-alanine acetyltransferase BASH2_05560 ENOG41072GX Peptidase M22 Glycoprotease BASH2_05561 ENOG4105K8N protein family UPF0079, ATPase BASH2_pXO10012 ENOG4105EKQ RNA-directed DNA polymerase BASH2_pXO10031 ENOG4105EKQ RNA-directed DNA polymerase BASH2_pXO10057 ENOG4105CNU cell division protein FtsK BASH2_pXO10105 ENOG4105DHF Membrane BASH2_pXO10112 ENOG4106AKK s-layer domain-containing protein BASH2_pXO10113 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BASH2_pXO10117 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BASH2_pXO10118 ENOG4105C6Y Udp-glucose 6-dehydrogenase BASH2_pXO10121 ENOG4105DQ6 Transposase BASH2_pXO10122 ENOG4105DQ6 Transposase BASH2_pXO10131 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BASH2_pXO10158 ENOG4105KRN Transcriptional regulator, abrb family BASH2_pXO10160 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BASH2_pXO10167 ENOG4108IBT Inherit from COG: transposase BASH2_pXO10169 ENOG4105DQ6 Transposase BASH2_pXO10172 ENOG4105DQ6 Transposase BASH2_pXO10173 ENOG4108MEK Metal-binding protein YodA BASH2_pXO10175 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BASH2_pXO10182 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BASH2_pXO20008 ENOG4105K4H Nlp p60 protein BASH2_pXO20041 ENOG4107QJE Chromosome Partitioning Protein BASH2_pXO20046 ENOG4105DQ6 Transposase BASH2_pXO20051 ENOG4105EWC Purine nucleoside phosphorylase BASH2_pXO20069 ENOG4105C3F Signal peptidase i BASH2_pXO20076 ENOG4105N14 lysine exporter protein LysE YggA BASH2_pXO20083 ENOG4108J59 Extracellular solute-binding protein, family 5 BASH2_pXO20086 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BASH2_pXO20098 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BASH2_pXO20099 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BASH2_tRNA025 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation