locus-tag	class	description
AW166_00010	COG0592	DNA-directed DNA polymerase activity
AW166_00015	COG2501	S4 domain
AW166_00025	COG0187	DNA topoisomerase II activity
AW166_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW166_00065	COG0516	GMP reductase activity
AW166_00065	COG0517	IMP dehydrogenase activity
AW166_00070	COG1686	Belongs to the peptidase S11 family
AW166_00100	COG1428	Deoxynucleoside kinase
AW166_00105	COG1428	Deoxynucleoside kinase
AW166_00110	COG1335	isochorismatase
AW166_00120	COG0590	tRNA wobble adenosine to inosine editing
AW166_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW166_00185	COG1982	Orn Lys Arg decarboxylase major
AW166_00195	COG0470	DNA polymerase III
AW166_00200	COG1774	PSP1 C-terminal conserved region
AW166_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW166_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW166_00225	COG2002	toxin-antitoxin pair type II binding
AW166_00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_00235	COG0084	hydrolase, TatD family'
AW166_00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW166_00255	COG4466	Protein conserved in bacteria
AW166_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW166_00275	COG0251	oxidation-reduction process
AW166_00290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AW166_00295	COG0193	aminoacyl-tRNA hydrolase activity
AW166_00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW166_00310	COG2002	toxin-antitoxin pair type II binding
AW166_00315	COG2244	polysaccharide biosynthetic process
AW166_00320	COG3956	TIGRFAM MazG family protein
AW166_00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW166_00345	COG1098	S1 RNA binding domain
AW166_00360	COG2208	phosphoserine phosphatase activity
AW166_00365	COG0037	tRNA processing
AW166_00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW166_00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW166_00400	COG0512	Glutamine amidotransferase of anthranilate synthase
AW166_00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW166_00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW166_00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW166_00425	COG1396	sequence-specific DNA binding
AW166_00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW166_00460	COG3880	PFAM UvrB UvrC protein
AW166_00470	COG0542	response to heat
AW166_00475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW166_00485	COG4956	integral membrane protein (PIN domain superfamily)
AW166_00505	COG1045	serine acetyltransferase
AW166_00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW166_00525	COG3688	RNA-binding protein containing a PIN domain
AW166_00535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW166_00540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW166_00545	COG0250	Participates in transcription elongation, termination and antitermination
AW166_00570	COG2813	Specifically methylates the guanine in position
AW166_00580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW166_00585	COG1358	cellular component organization or biogenesis
AW166_00690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AW166_00715	COG0201	protein transport
AW166_00725	COG0024	Methionine aminopeptidase
AW166_00735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW166_00765	COG1122	ATPase activity
AW166_00770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW166_00775	COG0101	tRNA pseudouridine synthase activity
AW166_00795	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_00800	COG0489	protein tyrosine kinase activity
AW166_00810	COG2194	sulfuric ester hydrolase activity
AW166_00815	COG0726	polysaccharide deacetylase
AW166_00900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW166_00905	COG4856	YbbR-like protein
AW166_00920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW166_00925	COG0596	Alpha beta hydrolase
AW166_00945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW166_00950	COG0823	Involved in the tonB-independent uptake of proteins
AW166_00950	COG1506	peptidase
AW166_00950	COG4946	Tricorn protease homolog
AW166_00985	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_00990	COG2011	ABC-type metal ion transport system permease component
AW166_00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_01000	COG1464	Belongs to the NlpA lipoprotein family
AW166_01015	COG0277	FAD linked oxidase domain protein
AW166_01020	COG2271	Major facilitator Superfamily
AW166_01030	COG2814	Major facilitator Superfamily
AW166_01045	COG0601	transmembrane transport
AW166_01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_01055	COG0444	Belongs to the ABC transporter superfamily
AW166_01060	COG4608	Belongs to the ABC transporter superfamily
AW166_01065	COG4166	transmembrane transport
AW166_01075	COG2207	Transcriptional regulator
AW166_01090	COG4166	transmembrane transport
AW166_01095	COG4166	transmembrane transport
AW166_01100	COG0656	L-ascorbic acid biosynthetic process
AW166_01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_01125	COG4149	molybdate abc transporter
AW166_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_01140	COG1910	domain protein
AW166_01155	COG0583	DNA-binding transcription factor activity
AW166_01160	COG0697	spore germination
AW166_01170	COG0204	Acyl-transferase
AW166_01180	COG1609	Transcriptional regulator
AW166_01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_01205	COG0084	hydrolase, TatD family'
AW166_01210	COG5298	Protein conserved in bacteria
AW166_01235	COG0488	(ABC) transporter
AW166_01250	COG0747	negative chemotaxis
AW166_01255	COG0601	transmembrane transport
AW166_01265	COG0444	Belongs to the ABC transporter superfamily
AW166_01270	COG4608	Belongs to the ABC transporter superfamily
AW166_01295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AW166_01300	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW166_01310	COG2814	Major facilitator Superfamily
AW166_01325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW166_01335	COG4294	response to UV
AW166_01340	COG0457	Tetratricopeptide repeat
AW166_01340	COG0705	Rhomboid family
AW166_01350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW166_01355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW166_01360	COG0864	Transcriptional regulator
AW166_01365	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW166_01370	COG2183	response to ionizing radiation
AW166_01465	COG0802	atpase or kinase
AW166_01470	COG1214	PFAM Peptidase M22, glycoprotease
AW166_01475	COG0456	acetyltransferase
AW166_01480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AW166_01485	COG0488	(ABC) transporter
AW166_01500	COG1266	CAAX protease self-immunity
AW166_01520	COG2252	PERMEase
AW166_01530	COG5002	protein histidine kinase activity
AW166_01560	COG2226	methyltransferase
AW166_01600	COG1968	undecaprenyl-diphosphatase activity
AW166_01615	COG2205	protein histidine kinase activity
AW166_01620	COG0745	RESPONSE REGULATOR receiver
AW166_01640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW166_01645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW166_01650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW166_01660	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW166_01675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW166_01685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW166_01695	COG0151	Belongs to the GarS family
AW166_01720	COG0210	DNA helicase
AW166_01730	COG4851	CamS sex pheromone cAM373 precursor
AW166_01750	COG1335	isochorismatase
AW166_01755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_01760	COG2011	ABC-type metal ion transport system permease component
AW166_01765	COG1464	Belongs to the NlpA lipoprotein family
AW166_01785	COG1846	Transcriptional regulator
AW166_01810	COG1597	lipid kinase activity
AW166_01815	COG0546	phosphoglycolate phosphatase activity
AW166_01820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW166_01830	COG1012	belongs to the aldehyde dehydrogenase family
AW166_01835	COG2076	Multidrug Resistance protein
AW166_01840	COG2309	aminopeptidase activity
AW166_01855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_01860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW166_01865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW166_01875	COG4807	Protein conserved in bacteria
AW166_01905	COG1473	amidohydrolase
AW166_01920	COG0450	alkyl hydroperoxide reductase
AW166_01925	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AW166_01935	COG0235	Class ii aldolase
AW166_01940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_01945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_01950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_01970	COG0166	Belongs to the GPI family
AW166_02005	COG5002	protein histidine kinase activity
AW166_02025	COG3541	Predicted nucleotidyltransferase
AW166_02030	COG2814	Major facilitator Superfamily
AW166_02035	COG0723	plastoquinol--plastocyanin reductase activity
AW166_02035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_02045	COG0765	amino acid transport
AW166_02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_02065	COG0840	transmembrane signaling receptor activity
AW166_02070	COG0840	transmembrane signaling receptor activity
AW166_02075	COG0366	Alpha amylase catalytic
AW166_02080	COG2190	(PTS) system
AW166_02080	COG1263	PTS System
AW166_02080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_02110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW166_02125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_02135	COG1116	anion transmembrane transporter activity
AW166_02140	COG0488	(ABC) transporter
AW166_02185	COG2270	Major facilitator Superfamily
AW166_02200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_02215	COG2310	stress, protein
AW166_02220	COG2310	stress, protein
AW166_02225	COG2310	stress, protein
AW166_02230	COG0861	Integral membrane protein TerC family
AW166_02240	COG3853	Toxic anion resistance protein (TelA)
AW166_02255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW166_02265	COG1295	ribonuclease BN
AW166_02270	COG2217	Heavy metal translocating P-type atpase
AW166_02275	COG0697	spore germination
AW166_02295	COG0586	Pfam SNARE associated Golgi protein
AW166_02310	COG3871	stress protein (general stress protein 26)
AW166_02315	COG0387	Pfam Sodium calcium exchanger
AW166_02325	COG0535	radical SAM domain protein
AW166_02350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW166_02355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW166_02360	COG0582	viral genome integration into host DNA
AW166_02365	COG1396	sequence-specific DNA binding
AW166_02380	COG1396	sequence-specific DNA binding
AW166_02415	COG1484	DNA-dependent DNA replication
AW166_02510	COG0582	viral genome integration into host DNA
AW166_02515	COG0582	viral genome integration into host DNA
AW166_02640	COG0101	tRNA pseudouridine synthase activity
AW166_02650	COG3829	transcription factor binding
AW166_02660	COG0833	amino acid
AW166_02665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_02695	COG2066	Belongs to the glutaminase family
AW166_02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_02700	COG1263	PTS System
AW166_02705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_02720	COG0463	Glycosyl transferase, family 2
AW166_02735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW166_02735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_02755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW166_02775	COG1228	amidohydrolase
AW166_02780	COG1090	epimerase
AW166_02810	COG1988	membrane-bound metal-dependent
AW166_02815	COG1194	a g-specific adenine glycosylase
AW166_02840	COG1132	(ABC) transporter
AW166_02845	COG4129	membrane
AW166_02850	COG0067	glutamate synthase
AW166_02850	COG0069	glutamate synthase activity
AW166_02850	COG0070	glutamate synthase
AW166_02860	COG4555	ABC transporter
AW166_02880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW166_02885	COG0735	belongs to the Fur family
AW166_03000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW166_03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW166_03015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW166_03025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW166_03040	COG2766	serine protein kinase
AW166_03065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_03075	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW166_03080	COG2268	Band 7 protein
AW166_03090	COG3290	protein histidine kinase activity
AW166_03100	COG2851	Citrate transporter
AW166_03120	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW166_03125	COG3842	ATPase activity
AW166_03130	COG1175	transmembrane transport
AW166_03135	COG0395	ABC-type sugar transport system, permease component
AW166_03145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW166_03150	COG0745	RESPONSE REGULATOR receiver
AW166_03155	COG5002	protein histidine kinase activity
AW166_03165	COG4990	cell redox homeostasis
AW166_03175	COG3290	protein histidine kinase activity
AW166_03180	COG4565	transcriptional regulatory protein
AW166_03185	COG3493	citrate carrier protein
AW166_03190	COG0281	malic enzyme
AW166_03205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_03215	COG5002	protein histidine kinase activity
AW166_03220	COG0745	RESPONSE REGULATOR receiver
AW166_03230	COG0456	acetyltransferase
AW166_03230	COG0454	-acetyltransferase
AW166_03235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW166_03240	COG3383	formate dehydrogenase (NAD+) activity
AW166_03245	COG2427	Protein of unknown function (DUF1641)
AW166_03260	COG0531	amino acid
AW166_03265	COG0640	Transcriptional regulator
AW166_03270	COG2217	Heavy metal translocating P-type atpase
AW166_03275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW166_03285	COG3227	Zinc metalloprotease (Elastase)
AW166_03305	COG2720	vancomycin resistance protein
AW166_03310	COG1316	TRANSCRIPTIONal
AW166_03315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_03320	COG0346	lactoylglutathione lyase activity
AW166_03325	COG1253	flavin adenine dinucleotide binding
AW166_03330	COG1027	Aspartate ammonia-lyase
AW166_03335	COG1620	l-lactate permease
AW166_03350	COG3104	oligopeptide transport
AW166_03355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_03360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_03365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_03375	COG2226	methyltransferase
AW166_03380	COG0156	8-amino-7-oxononanoate synthase activity
AW166_03385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_03395	COG4548	von Willebrand factor, type A
AW166_03400	COG0714	Associated with various cellular activities
AW166_03405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_03425	COG0531	amino acid
AW166_03430	COG2188	Transcriptional regulator
AW166_03435	COG1263	PTS System
AW166_03435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_03440	COG0366	Alpha amylase catalytic
AW166_03455	COG0697	spore germination
AW166_03465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_03470	COG1115	amino acid carrier protein
AW166_03475	COG1126	abc transporter atp-binding protein
AW166_03480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_03485	COG0765	amino acid transport
AW166_03490	COG0765	amino acid transport
AW166_03495	COG0833	amino acid
AW166_03520	COG2378	regulation of single-species biofilm formation
AW166_03525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW166_03530	COG5002	protein histidine kinase activity
AW166_03545	COG0659	secondary active sulfate transmembrane transporter activity
AW166_03560	COG0747	negative chemotaxis
AW166_03570	COG0601	transmembrane transport
AW166_03575	COG4608	Belongs to the ABC transporter superfamily
AW166_03585	COG2271	Major facilitator Superfamily
AW166_03590	COG1846	Transcriptional regulator
AW166_03595	COG0477	Major facilitator Superfamily
AW166_03600	COG0477	Major facilitator Superfamily
AW166_03605	COG1609	Transcriptional regulator
AW166_03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW166_03620	COG1129	ABC transporter
AW166_03625	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW166_03630	COG1879	ABC-type sugar transport system periplasmic component
AW166_03635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW166_03655	COG1063	alcohol dehydrogenase
AW166_03670	COG3568	Endonuclease Exonuclease Phosphatase
AW166_03695	COG1968	undecaprenyl-diphosphatase activity
AW166_03700	COG0840	transmembrane signaling receptor activity
AW166_03705	COG1388	LysM domain
AW166_03705	COG3584	3D domain protein
AW166_03710	COG1476	TRANSCRIPTIONal
AW166_03725	COG3104	oligopeptide transport
AW166_03730	COG1114	Component of the transport system for branched-chain amino acids
AW166_03745	COG1113	amino acid transport
AW166_03750	COG2252	PERMEase
AW166_03775	COG0569	domain protein
AW166_03775	COG0475	glutathione-regulated potassium exporter activity
AW166_03790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW166_03795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW166_03800	COG0833	amino acid
AW166_03805	COG4990	cell redox homeostasis
AW166_03820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_03825	COG0697	spore germination
AW166_03830	COG0531	amino acid
AW166_03845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_03850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_03855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_03855	COG1918	ferrous iron import across plasma membrane
AW166_03860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW166_03865	COG0573	inorganic phosphate transmembrane transporter activity
AW166_03870	COG0581	inorganic phosphate transmembrane transporter activity
AW166_03880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW166_03995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW166_04020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW166_04025	COG1116	anion transmembrane transporter activity
AW166_04030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_04035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_04040	COG0352	thiamine-phosphate diphosphorylase activity
AW166_04045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_04050	COG2104	thiamine diphosphate biosynthetic process
AW166_04060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_04065	COG0351	phosphomethylpyrimidine kinase
AW166_04110	COG2205	protein histidine kinase activity
AW166_04115	COG2814	Major facilitator Superfamily
AW166_04120	COG1846	Transcriptional regulator
AW166_04135	COG2252	PERMEase
AW166_04140	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW166_04160	COG1621	beta-fructofuranosidase activity
AW166_04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_04165	COG1263	PTS System
AW166_04170	COG1609	Transcriptional regulator
AW166_04180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_04185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW166_04225	COG0778	Nitroreductase
AW166_04230	COG2719	SpoVR family
AW166_04255	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW166_04260	COG1937	Protein conserved in bacteria
AW166_04265	COG0425	Belongs to the sulfur carrier protein TusA family
AW166_04265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_04270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_04275	COG0425	Belongs to the sulfur carrier protein TusA family
AW166_04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_04290	COG2210	Belongs to the sulfur carrier protein TusA family
AW166_04295	COG0730	response to heat
AW166_04305	COG1316	TRANSCRIPTIONal
AW166_04310	COG0604	alcohol dehydrogenase
AW166_04315	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW166_04330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_04330	COG3711	transcriptional antiterminator
AW166_04335	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_04340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_04360	COG1388	LysM domain
AW166_04360	COG3584	3D domain protein
AW166_04365	COG0577	efflux transmembrane transporter activity
AW166_04370	COG1136	(ABC) transporter
AW166_04380	COG5522	Integral membrane protein (intg_mem_TP0381)
AW166_04395	COG1114	Component of the transport system for branched-chain amino acids
AW166_04400	COG3546	catalase activity
AW166_04435	COG0586	Pfam SNARE associated Golgi protein
AW166_04470	COG0531	amino acid
AW166_04475	COG0475	glutathione-regulated potassium exporter activity
AW166_04485	COG1737	Transcriptional regulator
AW166_04495	COG1263	PTS System
AW166_04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_04505	COG2259	Doxx family
AW166_04520	COG0697	spore germination
AW166_04525	COG1522	sequence-specific DNA binding
AW166_04535	COG2076	Multidrug Resistance protein
AW166_04540	COG2076	Multidrug Resistance protein
AW166_04545	COG1309	transcriptional regulator
AW166_04550	COG2814	Major facilitator Superfamily
AW166_04555	COG1733	regulation of RNA biosynthetic process
AW166_04565	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_04570	COG4533	DNA binding
AW166_04575	COG2211	Major facilitator Superfamily
AW166_04585	COG0693	protein deglycase activity
AW166_04590	COG0693	protein deglycase activity
AW166_04590	COG0753	catalase activity
AW166_04600	COG0531	amino acid
AW166_04605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW166_04615	COG1012	belongs to the aldehyde dehydrogenase family
AW166_04625	COG1132	(ABC) transporter
AW166_04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_04640	COG0765	amino acid transport
AW166_04645	COG1126	abc transporter atp-binding protein
AW166_04660	COG0189	ligase activity
AW166_04690	COG0028	Belongs to the TPP enzyme family
AW166_04695	COG3527	Alpha-acetolactate decarboxylase
AW166_04710	COG0561	phosphatase activity
AW166_04725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW166_04740	COG0659	secondary active sulfate transmembrane transporter activity
AW166_04760	COG0653	protein targeting
AW166_04765	COG2244	polysaccharide biosynthetic process
AW166_04775	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_04780	COG4196	transglutaminase domain protein
AW166_04795	COG1696	Membrane protein involved in D-alanine export
AW166_04810	COG1024	Enoyl-CoA hydratase
AW166_04830	COG1363	Peptidase, m42
AW166_04850	COG3938	Belongs to the proline racemase family
AW166_04890	COG0601	transmembrane transport
AW166_04895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_04905	COG4608	Belongs to the ABC transporter superfamily
AW166_04935	COG0477	Major facilitator Superfamily
AW166_04940	COG3290	protein histidine kinase activity
AW166_04945	COG4565	transcriptional regulatory protein
AW166_04950	COG3181	Tripartite tricarboxylate transporter family receptor
AW166_04980	COG4978	Transcriptional regulator
AW166_04980	COG0789	Transcriptional regulator
AW166_04995	COG0305	Participates in initiation and elongation during chromosome replication
AW166_05035	COG0477	Major facilitator Superfamily
AW166_05085	COG3320	Male sterility
AW166_05085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW166_05110	COG1183	phosphatidylcholine synthase activity
AW166_05130	COG2376	Dihydroxyacetone kinase
AW166_05145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_05150	COG1959	2 iron, 2 sulfur cluster binding
AW166_05175	COG2770	Histidine kinase
AW166_05175	COG3437	response regulator, receiver
AW166_05225	COG3237	CsbD-like
AW166_05250	COG1191	sigma factor activity
AW166_05260	COG2208	phosphoserine phosphatase activity
AW166_05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW166_05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_05270	COG2205	protein histidine kinase activity
AW166_05270	COG2198	Histidine kinase
AW166_05270	COG0784	Response regulator, receiver
AW166_05295	COG0393	Putative heavy-metal-binding
AW166_05330	COG0420	3'-5' exonuclease activity
AW166_05335	COG4717	serine-type aminopeptidase activity
AW166_05355	COG1309	transcriptional regulator
AW166_05360	COG2814	Major facilitator Superfamily
AW166_05365	COG0346	lactoylglutathione lyase activity
AW166_05370	COG0346	lactoylglutathione lyase activity
AW166_05375	COG0457	Tetratricopeptide repeat
AW166_05380	COG2267	carboxylic ester hydrolase activity
AW166_05400	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW166_05405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW166_05415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW166_05455	COG0477	Major facilitator Superfamily
AW166_05460	COG0477	Major facilitator Superfamily
AW166_05470	COG3973	AAA domain
AW166_05475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_05500	COG4980	gas vesicle protein
AW166_05505	COG0537	adenosine 5'-monophosphoramidase activity
AW166_05510	COG1131	(ABC) transporter
AW166_05515	COG4473	ABC transporter
AW166_05525	COG1309	transcriptional regulator
AW166_05535	COG3402	PFAM membrane-flanked domain
AW166_05545	COG3428	Bacterial PH domain
AW166_05585	COG3402	PFAM membrane-flanked domain
AW166_05590	COG3428	Bacterial PH domain
AW166_05595	COG2329	Antibiotic biosynthesis monooxygenase
AW166_05600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_05605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW166_05650	COG1309	transcriptional regulator
AW166_05655	COG1511	domain protein
AW166_05680	COG1609	Transcriptional regulator
AW166_05690	COG1234	tRNA 3'-trailer cleavage
AW166_05695	COG0095	Lipoate-protein ligase
AW166_05705	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_05735	COG3209	COG3209 Rhs family protein
AW166_05780	COG1408	metallophosphoesterase
AW166_05785	COG1078	dGTPase activity
AW166_05795	COG1595	DNA-templated transcription, initiation
AW166_05800	COG2207	Transcriptional regulator
AW166_05800	COG3708	Transcriptional regulator
AW166_05815	COG2205	protein histidine kinase activity
AW166_05820	COG0745	RESPONSE REGULATOR receiver
AW166_05845	COG0501	Belongs to the peptidase M48B family
AW166_05850	COG0840	transmembrane signaling receptor activity
AW166_05855	COG0697	spore germination
AW166_05870	COG0497	DNA recombination
AW166_05875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW166_05880	COG2224	Isocitrate lyase
AW166_05890	COG1278	Cold shock
AW166_05905	COG4903	ComK protein
AW166_05910	COG0398	Pfam SNARE associated Golgi protein
AW166_05920	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW166_05925	COG1074	ATP-dependent DNA helicase activity
AW166_05970	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW166_05995	COG0367	asparagine synthase
AW166_06005	COG0753	catalase activity
AW166_06010	COG0004	ammonium transporteR
AW166_06035	COG2996	Protein conserved in bacteria
AW166_06045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_06070	COG0561	phosphatase activity
AW166_06085	COG0542	response to heat
AW166_06095	COG2267	carboxylic ester hydrolase activity
AW166_06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW166_06120	COG5504	Zn-dependent protease
AW166_06130	COG0180	Tryptophanyl-tRNA synthetase
AW166_06140	COG4166	transmembrane transport
AW166_06145	COG0601	transmembrane transport
AW166_06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_06155	COG0444	Belongs to the ABC transporter superfamily
AW166_06160	COG4608	Belongs to the ABC transporter superfamily
AW166_06165	COG0534	Mate efflux family protein
AW166_06170	COG4166	transmembrane transport
AW166_06185	COG1393	Belongs to the ArsC family
AW166_06190	COG0861	Integral membrane protein TerC family
AW166_06195	COG4862	establishment of competence for transformation
AW166_06200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_06210	COG1164	Oligoendopeptidase f
AW166_06225	COG2346	COG2346, Truncated hemoglobins
AW166_06230	COG4116	CYTH
AW166_06240	COG2357	RelA SpoT domain protein
AW166_06245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW166_06250	COG0564	pseudouridine synthase activity
AW166_06265	COG0772	Belongs to the SEDS family
AW166_06270	COG1216	Glycosyl transferase, family 2
AW166_06290	COG0463	Glycosyl transferase, family 2
AW166_06290	COG0457	Tetratricopeptide repeat
AW166_06310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW166_06325	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW166_06370	COG2153	protein acetylation
AW166_06375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW166_06380	COG2382	esterase
AW166_06395	COG5492	domain, Protein
AW166_06400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_06415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW166_06415	COG0512	Glutamine amidotransferase of anthranilate synthase
AW166_06450	COG1620	l-lactate permease
AW166_06455	COG5634	Uncharacterized conserved protein (DUF2278)
AW166_06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_06515	COG1476	TRANSCRIPTIONal
AW166_06575	COG2226	methyltransferase
AW166_06585	COG1686	Belongs to the peptidase S11 family
AW166_06590	COG0681	Belongs to the peptidase S26 family
AW166_06625	COG1012	belongs to the aldehyde dehydrogenase family
AW166_06630	COG3842	ATPase activity
AW166_06635	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW166_06640	COG1177	transmembrane transport
AW166_06645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW166_06655	COG2409	Drug exporters of the RND superfamily
AW166_06665	COG0564	pseudouridine synthase activity
AW166_06675	COG2340	Cysteine-rich secretory protein family
AW166_06680	COG0247	lactate metabolic process
AW166_06685	COG0277	FAD linked oxidase domain protein
AW166_06690	COG3835	regulator
AW166_06700	COG0745	RESPONSE REGULATOR receiver
AW166_06705	COG5002	protein histidine kinase activity
AW166_06710	COG2186	Transcriptional regulator
AW166_06730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW166_06740	COG2116	formate transmembrane transporter activity
AW166_06745	COG0861	Integral membrane protein TerC family
AW166_06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_06760	COG2030	dehydratase
AW166_06780	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
AW166_06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_06810	COG1840	ABC-type Fe3 transport system, periplasmic component
AW166_06825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW166_06840	COG1349	DNA-binding transcription factor activity
AW166_06865	COG2861	carbohydrate metabolic process
AW166_06875	COG3852	Histidine kinase
AW166_06880	COG1846	Transcriptional regulator
AW166_06890	COG2318	DinB family
AW166_06900	COG5002	protein histidine kinase activity
AW166_06910	COG0720	synthase
AW166_06925	COG4873	Protein conserved in bacteria
AW166_06960	COG1780	Probably involved in ribonucleotide reductase function
AW166_06980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW166_06985	COG1725	Transcriptional regulator
AW166_06990	COG1131	(ABC) transporter
AW166_07000	COG1131	(ABC) transporter
AW166_07005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_07020	COG1522	sequence-specific DNA binding
AW166_07030	COG1335	isochorismatase
AW166_07040	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_07045	COG2070	2-Nitropropane dioxygenase
AW166_07050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW166_07060	COG1696	Membrane protein involved in D-alanine export
AW166_07085	COG0716	FMN binding
AW166_07100	COG3173	Aminoglycoside phosphotransferase
AW166_07120	COG0534	Mate efflux family protein
AW166_07125	COG1968	undecaprenyl-diphosphatase activity
AW166_07140	COG1846	Transcriptional regulator
AW166_07150	COG1301	dicarboxylic acid transport
AW166_07155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_07160	COG4709	membrane
AW166_07165	COG3874	Sporulation protein YtfJ
AW166_07195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_07200	COG0028	Belongs to the TPP enzyme family
AW166_07205	COG0440	acetolactate synthase activity
AW166_07210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW166_07220	COG0473	3-isopropylmalate dehydrogenase activity
AW166_07245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW166_07280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW166_07295	COG1183	phosphatidylcholine synthase activity
AW166_07300	COG1368	sulfuric ester hydrolase activity
AW166_07310	COG0019	diaminopimelate decarboxylase activity
AW166_07330	COG0529	Catalyzes the synthesis of activated sulfate
AW166_07335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW166_07355	COG1648	precorrin-2 dehydrogenase activity
AW166_07365	COG0733	neurotransmitter:sodium symporter activity
AW166_07385	COG1757	Na H antiporter
AW166_07400	COG4758	membrane
AW166_07405	COG4585	Histidine kinase
AW166_07410	COG2197	response regulator
AW166_07420	COG1114	Component of the transport system for branched-chain amino acids
AW166_07430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW166_07455	COG1017	nitric oxide dioxygenase activity
AW166_07455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW166_07475	COG0730	response to heat
AW166_07480	COG0306	phosphate transporter
AW166_07485	COG1392	Phosphate transport regulator
AW166_07490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_07505	COG3852	Histidine kinase
AW166_07510	COG1801	Protein of unknown function DUF72
AW166_07520	COG0582	viral genome integration into host DNA
AW166_07525	COG5002	protein histidine kinase activity
AW166_07545	COG0392	lysyltransferase activity
AW166_07545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW166_07560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_07565	COG1686	Belongs to the peptidase S11 family
AW166_07570	COG2715	membrane protein required for spore maturation
AW166_07575	COG0700	Nucleoside recognition
AW166_07580	COG1187	pseudouridine synthase activity
AW166_07590	COG1333	cytochrome c biogenesis protein
AW166_07595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW166_07600	COG0745	RESPONSE REGULATOR receiver
AW166_07605	COG5002	protein histidine kinase activity
AW166_07610	COG2096	Adenosyltransferase
AW166_07625	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW166_07630	COG1141	Ferredoxin
AW166_07635	COG4955	Helix-turn-helix domain
AW166_07640	COG0514	ATP-dependent DNA helicase (RecQ)
AW166_07645	COG1266	CAAX protease self-immunity
AW166_07665	COG4862	establishment of competence for transformation
AW166_07670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW166_07690	COG0492	ferredoxin-NADP+ reductase activity
AW166_07695	COG0252	asparaginase activity
AW166_07765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_07780	COG0142	geranyltranstransferase activity
AW166_07790	COG0142	geranyltranstransferase activity
AW166_07795	COG0105	UTP biosynthetic process
AW166_07810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW166_07815	COG0457	Tetratricopeptide repeat
AW166_07835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW166_07845	COG4347	Protein of unknown function (DUF1405)
AW166_07860	COG2738	Putative neutral zinc metallopeptidase
AW166_07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_07880	COG1694	Mazg nucleotide pyrophosphohydrolase
AW166_07895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_07900	COG0438	transferase activity, transferring glycosyl groups
AW166_07940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW166_07940	COG1199	ATP-dependent helicase activity
AW166_07960	COG3935	DnaD domain protein
AW166_07965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW166_07975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_07975	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW166_08015	COG4474	Belongs to the UPF0398 family
AW166_08030	COG0116	Belongs to the methyltransferase superfamily
AW166_08040	COG1199	ATP-dependent helicase activity
AW166_08045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW166_08055	COG3173	Aminoglycoside phosphotransferase
AW166_08060	COG0024	Methionine aminopeptidase
AW166_08070	COG2233	PERMEase
AW166_08075	COG2311	Membrane
AW166_08080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_08090	COG0456	acetyltransferase
AW166_08125	COG0754	glutathionylspermidine amidase activity
AW166_08140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_08165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW166_08180	COG1215	transferase activity, transferring glycosyl groups
AW166_08200	COG0454	-acetyltransferase
AW166_08220	COG0328	RNA-DNA hybrid ribonuclease activity
AW166_08260	COG1280	lysine exporter protein (LysE YggA)
AW166_08275	COG3162	membrane
AW166_08280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_08285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_08295	COG0475	glutathione-regulated potassium exporter activity
AW166_08305	COG4978	Transcriptional regulator
AW166_08305	COG0789	Transcriptional regulator
AW166_08315	COG2323	membrane
AW166_08320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW166_08375	COG1923	regulation of RNA biosynthetic process
AW166_08385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW166_08390	COG1360	Flagellar Motor Protein
AW166_08395	COG2201	protein-glutamate methylesterase activity
AW166_08405	COG1776	CheC inhibitor of MCP methylation
AW166_08405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_08420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW166_08440	COG1256	bacterial-type flagellum assembly
AW166_08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW166_08470	COG1815	bacterial-type flagellum-dependent cell motility
AW166_08475	COG1558	bacterial-type flagellum-dependent cell motility
AW166_08480	COG1677	Flagellar hook-basal body complex protein FliE
AW166_08485	COG1766	The M ring may be actively involved in energy transduction
AW166_08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_08505	COG1157	protein secretion by the type III secretion system
AW166_08555	COG0463	Glycosyl transferase, family 2
AW166_08585	COG0463	Glycosyl transferase, family 2
AW166_08585	COG0457	Tetratricopeptide repeat
AW166_08610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW166_08615	COG0741	lytic transglycosylase activity
AW166_08630	COG1776	CheC inhibitor of MCP methylation
AW166_08630	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_08640	COG1338	Plays a role in the flagellum-specific transport system
AW166_08645	COG1987	bacterial-type flagellum assembly
AW166_08655	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW166_08660	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW166_08670	COG4786	Flagellar basal body rod
AW166_08675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_08700	COG1309	transcriptional regulator
AW166_08720	COG2329	Antibiotic biosynthesis monooxygenase
AW166_08750	COG3842	ATPase activity
AW166_08755	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_08760	COG1177	transmembrane transport
AW166_08765	COG1234	tRNA 3'-trailer cleavage
AW166_08790	COG1686	Belongs to the peptidase S11 family
AW166_08800	COG0406	alpha-ribazole phosphatase activity
AW166_08830	COG0367	asparagine synthase
AW166_08860	COG1802	Transcriptional regulator
AW166_08865	COG0697	spore germination
AW166_08870	COG0523	cobalamin synthesis protein
AW166_08875	COG0701	Predicted permease
AW166_08885	COG1216	Glycosyl transferase, family 2
AW166_08885	COG0438	transferase activity, transferring glycosyl groups
AW166_08890	COG1757	Na H antiporter
AW166_08895	COG0114	fumarate hydratase activity
AW166_08925	COG3340	Belongs to the peptidase S51 family
AW166_08945	COG0785	Cytochrome C biogenesis protein
AW166_08980	COG2733	membrane
AW166_09015	COG1131	(ABC) transporter
AW166_09030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_09035	COG0528	UMP kinase activity
AW166_09045	COG1027	Aspartate ammonia-lyase
AW166_09050	COG0281	malic enzyme
AW166_09055	COG4191	Histidine kinase
AW166_09060	COG0784	Response regulator, receiver
AW166_09065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_09125	COG1051	belongs to the nudix hydrolase family
AW166_09130	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_09155	COG1966	Carbon starvation protein
AW166_09170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_09180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW166_09190	COG4166	transmembrane transport
AW166_09195	COG2223	nitrite transmembrane transporter activity
AW166_09200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_09215	COG2244	polysaccharide biosynthetic process
AW166_09220	COG0733	neurotransmitter:sodium symporter activity
AW166_09230	COG5566	PFAM Mor transcription activator
AW166_09235	COG2323	membrane
AW166_09250	COG2084	Dehydrogenase
AW166_09265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_09275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_09280	COG0028	Belongs to the TPP enzyme family
AW166_09285	COG0440	acetolactate synthase activity
AW166_09290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW166_09300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW166_09325	COG2814	Major facilitator Superfamily
AW166_09330	COG3384	dioxygenase
AW166_09340	COG3279	Response regulator of the LytR AlgR family
AW166_09345	COG0427	acetyl-CoA hydrolase
AW166_09365	COG1073	alpha beta
AW166_09370	COG4166	transmembrane transport
AW166_09400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_09420	COG1914	H( )-stimulated, divalent metal cation uptake system
AW166_09435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW166_09470	COG2390	Transcriptional regulator
AW166_09480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_09485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW166_09500	COG4224	UPF0291 protein
AW166_09520	COG0006	proline dipeptidase activity
AW166_09525	COG2132	Multicopper oxidase
AW166_09555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_09570	COG1276	copper resistance
AW166_09570	COG2372	response to copper ion
AW166_09575	COG4549	nuclear export factor GLE1
AW166_09585	COG0697	spore germination
AW166_09590	COG0583	DNA-binding transcription factor activity
AW166_09595	COG1959	2 iron, 2 sulfur cluster binding
AW166_09600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW166_09605	COG0778	Nitroreductase
AW166_09620	COG0628	permease
AW166_09625	COG0039	L-malate dehydrogenase activity
AW166_09630	COG1231	oxidoreductase activity
AW166_09635	COG0523	cobalamin synthesis protein
AW166_09650	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_09655	COG2030	dehydratase
AW166_09660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_09670	COG0411	ABC transporter
AW166_09690	COG0583	DNA-binding transcription factor activity
AW166_09700	COG1942	4-Oxalocrotonate Tautomerase
AW166_09710	COG1846	Transcriptional regulator
AW166_09720	COG1271	oxidase subunit
AW166_09725	COG1294	oxidase, subunit
AW166_09730	COG4988	ABC transporter
AW166_09735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW166_09755	COG1686	Belongs to the peptidase S11 family
AW166_09770	COG1388	LysM domain
AW166_09770	COG0791	NLP P60 protein
AW166_09780	COG1132	(ABC) transporter
AW166_09785	COG1132	(ABC) transporter
AW166_09790	COG0745	RESPONSE REGULATOR receiver
AW166_09795	COG5002	protein histidine kinase activity
AW166_09805	COG0300	oxidoreductase activity
AW166_09820	COG0726	polysaccharide deacetylase
AW166_09840	COG0460	homoserine dehydrogenase
AW166_09865	COG1316	TRANSCRIPTIONal
AW166_09875	COG0745	RESPONSE REGULATOR receiver
AW166_09880	COG5002	protein histidine kinase activity
AW166_09885	COG0726	polysaccharide deacetylase
AW166_09895	COG1285	pathogenesis
AW166_09900	COG1247	-acetyltransferase
AW166_09910	COG4264	IucA IucC family
AW166_09915	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_09930	COG1082	Xylose isomerase domain protein TIM barrel
AW166_09945	COG1279	arginine transmembrane transporter activity
AW166_09955	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW166_09995	COG2002	toxin-antitoxin pair type II binding
AW166_10000	COG1404	Belongs to the peptidase S8 family
AW166_10005	COG0640	Transcriptional regulator
AW166_10010	COG0667	Aldo Keto reductase
AW166_10015	COG2814	Major facilitator Superfamily
AW166_10040	COG0840	transmembrane signaling receptor activity
AW166_10060	COG3949	Membrane
AW166_10065	COG0783	Belongs to the Dps family
AW166_10080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_10090	COG1231	oxidoreductase activity
AW166_10100	COG4989	oxidoreductase activity
AW166_10105	COG0523	cobalamin synthesis protein
AW166_10110	COG0456	acetyltransferase
AW166_10170	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW166_10170	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW166_10180	COG0702	epimerase
AW166_10190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW166_10200	COG4166	transmembrane transport
AW166_10215	COG0406	alpha-ribazole phosphatase activity
AW166_10225	COG5337	Spore coat protein CotH
AW166_10230	COG1051	belongs to the nudix hydrolase family
AW166_10235	COG0586	Pfam SNARE associated Golgi protein
AW166_10240	COG2244	polysaccharide biosynthetic process
AW166_10250	COG0701	Predicted permease
AW166_10255	COG3689	TIGRFAM TIGR03943 family protein
AW166_10260	COG1607	acyl-coa hydrolase
AW166_10265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_10280	COG0702	epimerase
AW166_10285	COG2839	Protein conserved in bacteria
AW166_10290	COG1253	flavin adenine dinucleotide binding
AW166_10305	COG1114	Component of the transport system for branched-chain amino acids
AW166_10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_10330	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_10340	COG1876	peptidase activity
AW166_10350	COG0154	amidase activity
AW166_10355	COG2211	Major facilitator Superfamily
AW166_10375	COG0561	phosphatase activity
AW166_10385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW166_10405	COG1819	glycosyl
AW166_10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_10415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_10440	COG0456	acetyltransferase
AW166_10490	COG3874	Sporulation protein YtfJ
AW166_10515	COG2226	methyltransferase
AW166_10535	COG1082	Xylose isomerase domain protein TIM barrel
AW166_10540	COG0346	lactoylglutathione lyase activity
AW166_10550	COG0604	alcohol dehydrogenase
AW166_10555	COG1595	DNA-templated transcription, initiation
AW166_10580	COG0386	Belongs to the glutathione peroxidase family
AW166_10585	COG1305	Transglutaminase-like
AW166_10590	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW166_10595	COG0714	Associated with various cellular activities
AW166_10610	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW166_10615	COG1140	nitrate reductase beta subunit
AW166_10620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW166_10625	COG2181	nitrate reductase activity
AW166_10645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW166_10650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW166_10655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_10660	COG0303	'Molybdopterin
AW166_10665	COG0314	molybdopterin synthase activity
AW166_10675	COG2223	nitrite transmembrane transporter activity
AW166_10690	COG1648	precorrin-2 dehydrogenase activity
AW166_10700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW166_10700	COG1587	Uroporphyrinogen-III synthase
AW166_10705	COG2146	nitrite reductase [NAD(P)H] activity
AW166_10710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW166_10715	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AW166_10750	COG2359	stage V sporulation protein S
AW166_10765	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_10780	COG1418	mRNA catabolic process
AW166_10785	COG0488	(ABC) transporter
AW166_10800	COG0629	single-stranded DNA binding
AW166_10815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW166_10820	COG1413	lyase activity
AW166_10835	COG2136	Putative SAM-dependent methyltransferase
AW166_10835	COG2521	methyltransferase
AW166_10840	COG0018	arginyl-trna synthetase
AW166_10865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW166_10880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW166_10885	COG0017	Asparaginyl-tRNA synthetase
AW166_10905	COG1674	ftsk spoiiie
AW166_11005	COG1929	Belongs to the glycerate kinase type-1 family
AW166_11010	COG0471	metal ion transport
AW166_11015	COG0745	RESPONSE REGULATOR receiver
AW166_11020	COG3850	Histidine kinase
AW166_11020	COG5002	protein histidine kinase activity
AW166_11035	COG0733	neurotransmitter:sodium symporter activity
AW166_11060	COG2610	gluconate transmembrane transporter activity
AW166_11065	COG1454	alcohol dehydrogenase
AW166_11070	COG1794	racemase activity, acting on amino acids and derivatives
AW166_11080	COG0456	acetyltransferase
AW166_11095	COG1131	(ABC) transporter
AW166_11100	COG4473	ABC transporter
AW166_11110	COG0546	phosphoglycolate phosphatase activity
AW166_11130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_11145	COG0768	penicillin binding
AW166_11150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_11155	COG0204	Acyl-transferase
AW166_11160	COG1272	protein, Hemolysin III
AW166_11170	COG0805	protein transport
AW166_11180	COG1307	EDD domain protein, DegV family
AW166_11185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW166_11190	COG1999	signal sequence binding
AW166_11195	COG0071	Belongs to the small heat shock protein (HSP20) family
AW166_11200	COG0367	asparagine synthase
AW166_11220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_11225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_11260	COG0668	transmembrane transport
AW166_11265	COG4585	Histidine kinase
AW166_11265	COG2203	Gaf domain
AW166_11270	COG2197	response regulator
AW166_11280	COG1737	Transcriptional regulator
AW166_11285	COG1064	alcohol dehydrogenase
AW166_11315	COG1070	Carbohydrate kinase
AW166_11350	COG1125	glycine betaine transport
AW166_11350	COG0517	IMP dehydrogenase activity
AW166_11355	COG1174	glycine betaine transport
AW166_11390	COG1253	flavin adenine dinucleotide binding
AW166_11395	COG1012	belongs to the aldehyde dehydrogenase family
AW166_11400	COG5506	Protein of unknown function (DUF1694)
AW166_11415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_11420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW166_11425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW166_11430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_11435	COG0456	acetyltransferase
AW166_11440	COG3829	transcription factor binding
AW166_11445	COG1509	lysine 2,3-aminomutase activity
AW166_11485	COG4326	sporulation control protein
AW166_11490	COG0671	phosphoesterase, PA-phosphatase related
AW166_11495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW166_11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_11530	COG1787	Restriction endonuclease
AW166_11530	COG1715	Restriction endonuclease
AW166_11615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_11655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_11655	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW166_11665	COG2814	Major facilitator Superfamily
AW166_11670	COG4841	protein insertion into membrane
AW166_11675	COG0372	Belongs to the citrate synthase family
AW166_11680	COG2079	MmgE PrpD family protein
AW166_11685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW166_11690	COG1960	acyl-CoA dehydrogenase activity
AW166_11695	COG2084	Dehydrogenase
AW166_11700	COG1012	belongs to the aldehyde dehydrogenase family
AW166_11705	COG1280	lysine exporter protein (LysE YggA)
AW166_11710	COG1024	Enoyl-CoA hydratase
AW166_11725	COG0420	3'-5' exonuclease activity
AW166_11730	COG0419	ATPase involved in DNA repair
AW166_11760	COG2223	nitrite transmembrane transporter activity
AW166_11765	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_11770	COG1169	isochorismate synthase
AW166_11775	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW166_11780	COG3433	isochorismatase activity
AW166_11780	COG1535	isochorismatase
AW166_11785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW166_11790	COG3251	PFAM MbtH domain protein
AW166_11795	COG2814	Major facilitator Superfamily
AW166_11810	COG0776	regulation of translation
AW166_11820	COG2318	DinB family
AW166_11830	COG1115	amino acid carrier protein
AW166_11845	COG2329	Antibiotic biosynthesis monooxygenase
AW166_11850	COG1187	pseudouridine synthase activity
AW166_11855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_11870	COG0596	Alpha beta hydrolase
AW166_11875	COG2814	Major facilitator Superfamily
AW166_11895	COG2226	methyltransferase
AW166_11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_11975	COG1247	-acetyltransferase
AW166_12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_12025	COG1278	Cold shock
AW166_12040	COG0010	Belongs to the arginase family
AW166_12045	COG0561	phosphatase activity
AW166_12090	COG0583	DNA-binding transcription factor activity
AW166_12095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW166_12110	COG0583	DNA-binding transcription factor activity
AW166_12115	COG2258	MOSC domain
AW166_12130	COG1132	(ABC) transporter
AW166_12135	COG1132	(ABC) transporter
AW166_12155	COG1396	sequence-specific DNA binding
AW166_12185	COG1595	DNA-templated transcription, initiation
AW166_12235	COG2971	BadF BadG BcrA BcrD
AW166_12240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_12245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW166_12265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_12295	COG1309	transcriptional regulator
AW166_12310	COG1136	(ABC) transporter
AW166_12310	COG0577	efflux transmembrane transporter activity
AW166_12315	COG0500	methyltransferase
AW166_12315	COG3615	Tellurite resistance protein tehB
AW166_12325	COG2226	methyltransferase
AW166_12330	COG3961	Belongs to the TPP enzyme family
AW166_12335	COG1846	Transcriptional regulator
AW166_12375	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW166_12390	COG1595	DNA-templated transcription, initiation
AW166_12400	COG0768	penicillin binding
AW166_12410	COG2367	Beta-lactamase
AW166_12415	COG0671	phosphoesterase, PA-phosphatase related
AW166_12420	COG1609	Transcriptional regulator
AW166_12425	COG2814	Major facilitator Superfamily
AW166_12430	COG0673	inositol 2-dehydrogenase activity
AW166_12440	COG1012	belongs to the aldehyde dehydrogenase family
AW166_12460	COG3718	enzyme involved in inositol metabolism
AW166_12485	COG0457	Tetratricopeptide repeat
AW166_12490	COG1476	TRANSCRIPTIONal
AW166_12505	COG1876	peptidase activity
AW166_12525	COG1309	transcriptional regulator
AW166_12545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_12555	COG1252	NADH dehydrogenase
AW166_12560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_12575	COG1131	(ABC) transporter
AW166_12585	COG1309	transcriptional regulator
AW166_12600	COG1960	acyl-CoA dehydrogenase activity
AW166_12605	COG0439	Biotin carboxylase
AW166_12610	COG0511	ligase activity, forming carbon-carbon bonds
AW166_12615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW166_12620	COG1024	Enoyl-CoA hydratase
AW166_12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW166_12630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_12640	COG1247	-acetyltransferase
AW166_12645	COG0572	uridine kinase
AW166_12655	COG2318	DinB family
AW166_12660	COG1686	Belongs to the peptidase S11 family
AW166_12685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW166_12725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_12725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_12740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_12750	COG2814	Major facilitator Superfamily
AW166_12770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_12790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_12805	COG1063	alcohol dehydrogenase
AW166_12820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_12825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_12840	COG3773	Cell wall hydrolase
AW166_12850	COG0745	RESPONSE REGULATOR receiver
AW166_12880	COG1136	(ABC) transporter
AW166_12905	COG0460	homoserine dehydrogenase
AW166_12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_12920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW166_12995	COG2124	cytochrome p450
AW166_13030	COG0561	phosphatase activity
AW166_13040	COG5002	protein histidine kinase activity
AW166_13050	COG1819	glycosyl
AW166_13055	COG1794	racemase activity, acting on amino acids and derivatives
AW166_13065	COG1122	ATPase activity
AW166_13075	COG2205	protein histidine kinase activity
AW166_13090	COG0604	alcohol dehydrogenase
AW166_13105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_13140	COG0693	protein deglycase activity
AW166_13170	COG2814	Major facilitator Superfamily
AW166_13185	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_13205	COG0697	spore germination
AW166_13240	COG2223	nitrite transmembrane transporter activity
AW166_13255	COG2816	NAD+ diphosphatase activity
AW166_13260	COG0592	DNA-directed DNA polymerase activity
AW166_13265	COG1051	belongs to the nudix hydrolase family
AW166_13300	COG3878	Protein conserved in bacteria
AW166_13330	COG4667	esterase of the alpha-beta hydrolase superfamily
AW166_13355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW166_13370	COG0322	excinuclease ABC activity
AW166_13410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_13435	COG1011	Hydrolase
AW166_13455	COG0076	glutamate decarboxylase activity
AW166_13470	COG1523	belongs to the glycosyl hydrolase 13 family
AW166_13475	COG3227	Zinc metalloprotease (Elastase)
AW166_13495	COG0201	protein transport
AW166_13505	COG0697	spore germination
AW166_13510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_13540	COG4129	membrane
AW166_13545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_13560	COG2959	enzyme of heme biosynthesis
AW166_13565	COG3773	Cell wall hydrolase
AW166_13565	COG3409	Peptidoglycan-binding domain 1 protein
AW166_13580	COG3483	tryptophan 2,3-dioxygenase activity
AW166_13585	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AW166_13590	COG3844	kynureninase activity
AW166_13595	COG1309	transcriptional regulator
AW166_13625	COG3284	Transcriptional regulator
AW166_13645	COG1349	DNA-binding transcription factor activity
AW166_13665	COG1959	2 iron, 2 sulfur cluster binding
AW166_13680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW166_13685	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_13690	COG0022	dehydrogenase e1 component
AW166_13695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_13705	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_13710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_13710	COG0456	acetyltransferase
AW166_13745	COG4176	ABC-type proline glycine betaine transport system permease component
AW166_13750	COG4175	Glycine betaine
AW166_13750	COG0517	IMP dehydrogenase activity
AW166_13760	COG0740	serine-type endopeptidase activity
AW166_13775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AW166_13780	COG2153	protein acetylation
AW166_13785	COG3397	chitin binding
AW166_13800	COG2205	protein histidine kinase activity
AW166_13830	COG0658	competence protein
AW166_13830	COG2333	competence protein COMEC
AW166_13880	COG3973	AAA domain
AW166_13895	COG2105	PFAM AIG2 family protein
AW166_13900	COG0514	ATP-dependent DNA helicase (RecQ)
AW166_13930	COG4637	Psort location Cytoplasmic, score
AW166_13955	COG3397	chitin binding
AW166_13965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW166_13970	COG1115	amino acid carrier protein
AW166_13975	COG1012	belongs to the aldehyde dehydrogenase family
AW166_13980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW166_13990	COG3938	Belongs to the proline racemase family
AW166_13995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_14035	COG0586	Pfam SNARE associated Golgi protein
AW166_14050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW166_14055	COG0519	Catalyzes the synthesis of GMP from XMP
AW166_14060	COG4166	transmembrane transport
AW166_14070	COG4948	Mandelate Racemase Muconate Lactonizing
AW166_14110	COG2936	dipeptidyl-peptidase activity
AW166_14115	COG5002	protein histidine kinase activity
AW166_14120	COG0745	RESPONSE REGULATOR receiver
AW166_14160	COG1307	EDD domain protein, DegV family
AW166_14180	COG2814	Major facilitator Superfamily
AW166_14190	COG1664	Polymer-forming cytoskeletal
AW166_14195	COG0789	Transcriptional regulator
AW166_14200	COG4533	DNA binding
AW166_14205	COG0477	Major facilitator Superfamily
AW166_14205	COG2814	Major facilitator Superfamily
AW166_14225	COG2261	transglycosylase associated protein
AW166_14240	COG2226	methyltransferase
AW166_14275	COG0436	Aminotransferase
AW166_14280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW166_14285	COG5146	pantothenate kinase activity
AW166_14310	COG1131	(ABC) transporter
AW166_14360	COG0628	permease
AW166_14375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_14380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_14385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_14390	COG1116	anion transmembrane transporter activity
AW166_14430	COG2746	aminoglycoside 3-N-acetyltransferase activity
AW166_14455	COG0697	spore germination
AW166_14460	COG2318	DinB family
AW166_14480	COG4912	Dna alkylation repair
AW166_14490	COG0726	polysaccharide deacetylase
AW166_14500	COG0861	Integral membrane protein TerC family
AW166_14505	COG1368	sulfuric ester hydrolase activity
AW166_14510	COG0488	(ABC) transporter
AW166_14520	COG1033	growth of symbiont in host cell
AW166_14520	COG2409	Drug exporters of the RND superfamily
AW166_14525	COG2409	Drug exporters of the RND superfamily
AW166_14525	COG1033	growth of symbiont in host cell
AW166_14530	COG1033	growth of symbiont in host cell
AW166_14530	COG2409	Drug exporters of the RND superfamily
AW166_14535	COG1309	transcriptional regulator
AW166_14550	COG0287	Prephenate dehydrogenase
AW166_14555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW166_14560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW166_14565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW166_14565	COG1605	Chorismate mutase
AW166_14600	COG3584	3D domain protein
AW166_14600	COG1388	LysM domain
AW166_14610	COG1595	DNA-templated transcription, initiation
AW166_14635	COG1879	ABC-type sugar transport system periplasmic component
AW166_14645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW166_14655	COG2390	Transcriptional regulator
AW166_14690	COG2329	Antibiotic biosynthesis monooxygenase
AW166_14710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_14720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW166_14725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_14730	COG4187	Peptidase family M20/M25/M40
AW166_14735	COG1414	Transcriptional regulator
AW166_14740	COG0833	amino acid
AW166_14745	COG1690	Belongs to the RtcB family
AW166_14750	COG3239	Fatty acid desaturase
AW166_14755	COG1785	Belongs to the alkaline phosphatase family
AW166_14765	COG3655	Transcriptional regulator
AW166_14780	COG4377	Putative membrane peptidase family (DUF2324)
AW166_14790	COG3279	Response regulator of the LytR AlgR family
AW166_14800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_14805	COG0346	lactoylglutathione lyase activity
AW166_14825	COG0714	Associated with various cellular activities
AW166_14850	COG0463	Glycosyl transferase, family 2
AW166_14875	COG0463	Glycosyl transferase, family 2
AW166_14885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW166_14890	COG0753	catalase activity
AW166_14900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW166_14925	COG0714	Associated with various cellular activities
AW166_14935	COG0778	Nitroreductase
AW166_14940	COG1846	Transcriptional regulator
AW166_14975	COG1725	Transcriptional regulator
AW166_14985	COG0577	efflux transmembrane transporter activity
AW166_14985	COG1136	(ABC) transporter
AW166_15010	COG2207	Transcriptional regulator
AW166_15015	COG0456	acetyltransferase
AW166_15035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_15055	COG0642	Histidine kinase
AW166_15060	COG0745	RESPONSE REGULATOR receiver
AW166_15065	COG0596	Alpha beta hydrolase
AW166_15095	COG0730	response to heat
AW166_15105	COG0833	amino acid
AW166_15115	COG4335	DNA alkylation repair
AW166_15165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW166_15205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW166_15210	COG1414	Transcriptional regulator
AW166_15225	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_15230	COG0640	Transcriptional regulator
AW166_15240	COG1960	acyl-CoA dehydrogenase activity
AW166_15275	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW166_15290	COG0574	Belongs to the PEP-utilizing enzyme family
AW166_15290	COG3848	Pyruvate phosphate dikinase
AW166_15295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_15310	COG5577	PFAM Coat F domain
AW166_15315	COG3403	YqcI/YcgG family
AW166_15320	COG1280	lysine exporter protein (LysE YggA)
AW166_15355	COG1063	alcohol dehydrogenase
AW166_15370	COG1027	Aspartate ammonia-lyase
AW166_15375	COG0252	asparaginase activity
AW166_15380	COG1396	sequence-specific DNA binding
AW166_15390	COG0322	excinuclease ABC activity
AW166_15395	COG0531	amino acid
AW166_15400	COG1114	Component of the transport system for branched-chain amino acids
AW166_15405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_15415	COG0281	malic enzyme
AW166_15440	COG0697	spore germination
AW166_15445	COG0784	Response regulator, receiver
AW166_15455	COG2066	Belongs to the glutaminase family
AW166_15485	COG0737	Belongs to the 5'-nucleotidase family
AW166_15490	COG0753	catalase activity
AW166_15495	COG2267	carboxylic ester hydrolase activity
AW166_15500	COG1335	isochorismatase
AW166_15520	COG0583	DNA-binding transcription factor activity
AW166_15565	COG0415	Belongs to the DNA photolyase family
AW166_15570	COG0288	reversible hydration of carbon dioxide
AW166_15580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW166_15585	COG5609	conserved protein (DUF2294)
AW166_15595	COG1575	Belongs to the MenA family. Type 1 subfamily
AW166_15600	COG2267	carboxylic ester hydrolase activity
AW166_15605	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW166_15610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW166_15615	COG1121	(ABC) transporter
AW166_15645	COG0798	PFAM Bile acid sodium symporter
AW166_15650	COG0346	lactoylglutathione lyase activity
AW166_15655	COG0640	Transcriptional regulator
AW166_15670	COG0443	Heat shock 70 kDa protein
AW166_15685	COG1522	sequence-specific DNA binding
AW166_15700	COG0346	lactoylglutathione lyase activity
AW166_15725	COG2169	Transcriptional regulator
AW166_15770	COG2814	Major facilitator Superfamily
AW166_15795	COG0745	RESPONSE REGULATOR receiver
AW166_15800	COG5002	protein histidine kinase activity
AW166_15800	COG3850	Histidine kinase
AW166_15830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AW166_15855	COG1476	TRANSCRIPTIONal
AW166_15870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_15875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_15885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_15890	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW166_15905	COG1136	(ABC) transporter
AW166_15910	COG0577	efflux transmembrane transporter activity
AW166_15930	COG3850	Histidine kinase
AW166_15930	COG5002	protein histidine kinase activity
AW166_15940	COG2364	Membrane
AW166_15945	COG1846	Transcriptional regulator
AW166_15955	COG2808	Putative FMN-binding domain
AW166_15960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_15965	COG2271	Major facilitator Superfamily
AW166_15970	COG1556	Lactate utilization protein
AW166_15975	COG1139	Iron-sulfur cluster binding protein
AW166_15985	COG0583	DNA-binding transcription factor activity
AW166_15995	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_16020	COG0738	Major facilitator superfamily
AW166_16025	COG0673	inositol 2-dehydrogenase activity
AW166_16030	COG0561	phosphatase activity
AW166_16040	COG1609	Transcriptional regulator
AW166_16045	COG0457	Tetratricopeptide repeat
AW166_16065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW166_16095	COG0534	Mate efflux family protein
AW166_16110	COG2814	Major facilitator Superfamily
AW166_16115	COG1309	transcriptional regulator
AW166_16130	COG0814	amino acid
AW166_16135	COG1760	l-serine dehydratase
AW166_16140	COG1760	l-serine dehydratase
AW166_16150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW166_16155	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW166_16165	COG1335	isochorismatase
AW166_16170	COG1522	sequence-specific DNA binding
AW166_16175	COG0531	amino acid
AW166_16190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW166_16210	COG1595	DNA-templated transcription, initiation
AW166_16225	COG0662	Cupin 2, conserved barrel domain protein
AW166_16235	COG2207	Transcriptional regulator
AW166_16235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_16290	COG0477	Major facilitator Superfamily
AW166_16300	COG1846	Transcriptional regulator
AW166_16305	COG2814	Major facilitator Superfamily
AW166_16320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_16325	COG1131	(ABC) transporter
AW166_16345	COG2076	Multidrug Resistance protein
AW166_16350	COG1309	transcriptional regulator
AW166_16365	COG2031	fatty acid transporter
AW166_16375	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_16405	COG1122	ATPase activity
AW166_16410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW166_16425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AW166_16430	COG1288	antiporter activity
AW166_16435	COG2356	endonuclease I
AW166_16450	COG3620	sequence-specific DNA binding
AW166_16455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_16460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW166_16465	COG0124	histidyl-tRNA synthetase
AW166_16480	COG1733	regulation of RNA biosynthetic process
AW166_16485	COG0778	Nitroreductase
AW166_16505	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_16515	COG1131	(ABC) transporter
AW166_16540	COG1011	Hydrolase
AW166_16575	COG0346	lactoylglutathione lyase activity
AW166_16580	COG1940	carbohydrate kinase activity
AW166_16585	COG0738	Major facilitator superfamily
AW166_16590	COG0110	maltose O-acetyltransferase activity
AW166_16605	COG1136	(ABC) transporter
AW166_16610	COG0180	Tryptophanyl-tRNA synthetase
AW166_16615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW166_16620	COG0628	permease
AW166_16640	COG2226	methyltransferase
AW166_16650	COG0477	Major facilitator Superfamily
AW166_16680	COG1253	flavin adenine dinucleotide binding
AW166_16685	COG0789	Transcriptional regulator
AW166_16690	COG0697	spore germination
AW166_16695	COG1357	PFAM Pentapeptide repeats (8 copies)
AW166_16700	COG3813	Protein conserved in bacteria
AW166_16705	COG2706	6-phosphogluconolactonase activity
AW166_16710	COG1070	Carbohydrate kinase
AW166_16720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW166_16725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW166_16735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW166_16740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW166_16745	COG0604	alcohol dehydrogenase
AW166_16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_16770	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_16795	COG0656	L-ascorbic acid biosynthetic process
AW166_16800	COG2814	Major facilitator Superfamily
AW166_16815	COG0346	lactoylglutathione lyase activity
AW166_16820	COG0814	amino acid
AW166_16845	COG1393	Belongs to the ArsC family
AW166_16855	COG1733	regulation of RNA biosynthetic process
AW166_16860	COG2188	Transcriptional regulator
AW166_16870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW166_16875	COG1733	regulation of RNA biosynthetic process
AW166_16880	COG1733	regulation of RNA biosynthetic process
AW166_16895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_16915	COG0384	phenazine biosynthesis protein PhzF
AW166_16925	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_16935	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_16945	COG1733	regulation of RNA biosynthetic process
AW166_16980	COG1191	sigma factor activity
AW166_16995	COG1309	transcriptional regulator
AW166_17015	COG3152	Membrane
AW166_17040	COG1151	hydroxylamine reductase activity
AW166_17050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_17055	COG3409	Peptidoglycan-binding domain 1 protein
AW166_17055	COG3757	hydrolase, family 25
AW166_17090	COG2072	flavoprotein involved in K transport
AW166_17130	COG1113	amino acid transport
AW166_17135	COG2814	Major facilitator Superfamily
AW166_17170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_17175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_17195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_17215	COG3739	integral membrane protein
AW166_17220	COG0384	phenazine biosynthesis protein PhzF
AW166_17250	COG0583	DNA-binding transcription factor activity
AW166_17270	COG1193	negative regulation of DNA recombination
AW166_17285	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW166_17290	COG1164	Oligoendopeptidase f
AW166_17295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_17325	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_17350	COG0640	Transcriptional regulator
AW166_17355	COG0604	alcohol dehydrogenase
AW166_17375	COG2808	Putative FMN-binding domain
AW166_17380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_17390	COG0385	Bile acid
AW166_17395	COG0277	FAD linked oxidase domain protein
AW166_17430	COG1216	Glycosyl transferase, family 2
AW166_17435	COG1024	Enoyl-CoA hydratase
AW166_17445	COG1285	pathogenesis
AW166_17455	COG2514	catechol 2,3-dioxygenase activity
AW166_17460	COG2720	vancomycin resistance protein
AW166_17490	COG1278	Cold shock
AW166_17500	COG0716	FMN binding
AW166_17530	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_17540	COG0165	Argininosuccinate lyase
AW166_17555	COG4145	pantothenate transmembrane transporter activity
AW166_17560	COG3924	membrane
AW166_17565	COG1012	belongs to the aldehyde dehydrogenase family
AW166_17570	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_17580	COG1657	PFAM Prenyltransferase squalene oxidase
AW166_17585	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW166_17590	COG2962	Rard protein
AW166_17595	COG3326	Membrane
AW166_17610	COG0489	protein tyrosine kinase activity
AW166_17620	COG0314	molybdopterin synthase activity
AW166_17625	COG0303	'Molybdopterin
AW166_17630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_17635	COG2116	formate transmembrane transporter activity
AW166_17645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW166_17650	COG5609	conserved protein (DUF2294)
AW166_17655	COG2427	Protein of unknown function (DUF1641)
AW166_17660	COG3383	formate dehydrogenase (NAD+) activity
AW166_17670	COG0697	spore germination
AW166_17710	COG2226	methyltransferase
AW166_17715	COG4166	transmembrane transport
AW166_17720	COG4166	transmembrane transport
AW166_17725	COG4166	transmembrane transport
AW166_17735	COG1316	TRANSCRIPTIONal
AW166_17745	COG1595	DNA-templated transcription, initiation
AW166_17770	COG1131	(ABC) transporter
AW166_17780	COG0673	inositol 2-dehydrogenase activity
AW166_17785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW166_17790	COG0187	DNA topoisomerase II activity
AW166_17800	COG1832	CoA-binding protein
AW166_17805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_17810	COG0745	RESPONSE REGULATOR receiver
AW166_17825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_17830	COG4841	protein insertion into membrane
AW166_17835	COG0824	Thioesterase
AW166_17865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_17875	COG2274	protein secretion by the type I secretion system
AW166_17880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW166_17890	COG0726	polysaccharide deacetylase
AW166_17910	COG2211	Major facilitator Superfamily
AW166_17920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_17935	COG0183	Belongs to the thiolase family
AW166_17940	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_17945	COG1268	BioY protein
AW166_17950	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_17995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_18005	COG5002	protein histidine kinase activity
AW166_18010	COG0400	carboxylic ester hydrolase activity
AW166_18015	COG0346	lactoylglutathione lyase activity
AW166_18020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_18025	COG0069	glutamate synthase activity
AW166_18030	COG1902	pentaerythritol trinitrate reductase activity
AW166_18035	COG1329	Transcriptional regulator
AW166_18040	COG0010	Belongs to the arginase family
AW166_18065	COG2226	methyltransferase
AW166_18120	COG4846	Membrane protein involved in cytochrome C biogenesis
AW166_18125	COG0785	Cytochrome C biogenesis protein
AW166_18135	COG0583	DNA-binding transcription factor activity
AW166_18140	COG1380	Effector of murein hydrolase LrgA
AW166_18145	COG1346	cytolysis
AW166_18160	COG0730	response to heat
AW166_18170	COG3409	Peptidoglycan-binding domain 1 protein
AW166_18170	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_18185	COG1132	(ABC) transporter
AW166_18190	COG1132	(ABC) transporter
AW166_18225	COG3639	organic phosphonate transmembrane transporter activity
AW166_18230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AW166_18245	COG0737	Belongs to the 5'-nucleotidase family
AW166_18255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW166_18275	COG1695	Transcriptional regulator
AW166_18310	COG1388	LysM domain
AW166_18310	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_18310	COG3409	Peptidoglycan-binding domain 1 protein
AW166_18315	COG4824	toxin secretion phage lysis holin
AW166_18480	COG1595	DNA-templated transcription, initiation
AW166_18525	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AW166_18605	COG1396	sequence-specific DNA binding
AW166_18630	COG0174	glutamine synthetase
AW166_18635	COG0789	Transcriptional regulator
AW166_18640	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW166_18650	COG2860	membrane
AW166_18655	COG0464	growth
AW166_18685	COG1388	LysM domain
AW166_18685	COG3584	3D domain protein
AW166_18690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_18690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW166_18690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW166_18695	COG1105	Belongs to the carbohydrate kinase PfkB family
AW166_18700	COG1349	DNA-binding transcription factor activity
AW166_18710	COG2322	membrane
AW166_18725	COG1113	amino acid transport
AW166_18735	COG1408	metallophosphoesterase
AW166_18740	COG2116	formate transmembrane transporter activity
AW166_18750	COG2217	Heavy metal translocating P-type atpase
AW166_18755	COG2608	mercury ion transmembrane transporter activity
AW166_18760	COG1937	Protein conserved in bacteria
AW166_18770	COG2819	hydrolase of the alpha beta superfamily
AW166_18775	COG1120	ATPase activity
AW166_18780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_18785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_18790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_18800	COG0708	Exodeoxyribonuclease III
AW166_18805	COG2169	Transcriptional regulator
AW166_18810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW166_18815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW166_18825	COG2364	Membrane
AW166_18840	COG2267	carboxylic ester hydrolase activity
AW166_18845	COG0346	lactoylglutathione lyase activity
AW166_18850	COG3300	MHYT domain
AW166_18850	COG5001	Diguanylate cyclase
AW166_18870	COG1346	cytolysis
AW166_18875	COG1380	Effector of murein hydrolase LrgA
AW166_18880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_18885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_18885	COG0596	Alpha beta hydrolase
AW166_18890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_18905	COG1404	Belongs to the peptidase S8 family
AW166_18910	COG3773	Cell wall hydrolase
AW166_18915	COG0562	UDP-galactopyranose mutase
AW166_18920	COG1368	sulfuric ester hydrolase activity
AW166_18925	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_18935	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW166_18980	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW166_18985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW166_18990	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW166_18995	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW166_18995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW166_19005	COG2359	stage V sporulation protein S
AW166_19010	COG1692	metallophosphoesterase
AW166_19035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW166_19040	COG1426	Protein conserved in bacteria
AW166_19055	COG0300	oxidoreductase activity
AW166_19060	COG0612	Peptidase, M16
AW166_19065	COG0612	Peptidase, M16
AW166_19095	COG2188	Transcriptional regulator
AW166_19100	COG1674	ftsk spoiiie
AW166_19110	COG0740	serine-type endopeptidase activity
AW166_19115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW166_19130	COG0527	aspartate kinase activity
AW166_19135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW166_19140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW166_19145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW166_19150	COG1873	PFAM PRC-barrel domain
AW166_19155	COG0612	Peptidase, M16
AW166_19160	COG0726	polysaccharide deacetylase
AW166_19175	COG0196	riboflavin kinase activity
AW166_19180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW166_19190	COG1550	Protein conserved in bacteria
AW166_19200	COG1358	cellular component organization or biogenesis
AW166_19205	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW166_19210	COG0195	Participates in both transcription termination and antitermination
AW166_19230	COG0750	zinc metalloprotease
AW166_19235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW166_19240	COG4589	Belongs to the CDS family
AW166_19245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW166_19255	COG0528	UMP kinase activity
AW166_19285	COG4974	Belongs to the 'phage' integrase family
AW166_19295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW166_19305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW166_19345	COG1837	Belongs to the UPF0109 family
AW166_19355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW166_19365	COG0552	protein localization to endoplasmic reticulum
AW166_19370	COG1196	nuclear chromosome segregation
AW166_19385	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_19390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW166_19405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW166_19410	COG1461	Dihydroxyacetone kinase
AW166_19415	COG1302	Protein conserved in bacteria
AW166_19430	COG1564	THIamine pyrophosphokinase
AW166_19435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW166_19440	COG1162	GTPase activity
AW166_19445	COG0515	serine threonine protein kinase
AW166_19445	COG2815	serine threonine protein kinase
AW166_19450	COG0631	protein serine/threonine phosphatase activity
AW166_19460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW166_19460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW166_19470	COG0242	peptide deformylase activity
AW166_19475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW166_19480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW166_19490	COG0194	GDP metabolic process
AW166_19500	COG1561	YicC-like family, N-terminal region
AW166_19505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW166_19515	COG0006	proline dipeptidase activity
AW166_19530	COG3069	C4-dicarboxylate transmembrane transporter activity
AW166_19570	COG0505	Belongs to the CarA family
AW166_19595	COG0564	pseudouridine synthase activity
AW166_19610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW166_19615	COG3599	regulation of cell shape
AW166_19620	COG2302	S4 RNA-binding domain
AW166_19625	COG0762	integral membrane protein
AW166_19635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW166_19645	COG1873	PFAM PRC-barrel domain
AW166_19650	COG1191	sigma factor activity
AW166_19655	COG1191	sigma factor activity
AW166_19665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW166_19670	COG0849	cell division
AW166_19675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW166_19680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW166_19685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW166_19690	COG0772	Belongs to the SEDS family
AW166_19705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_19710	COG0768	penicillin binding
AW166_19720	COG4839	cell division protein FtsL
AW166_19735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW166_19755	COG1399	metal-binding, possibly nucleic acid-binding protein
AW166_19805	COG4824	toxin secretion phage lysis holin
AW166_19900	COG4626	Terminase
AW166_19900	COG1802	Transcriptional regulator
AW166_19925	COG0582	viral genome integration into host DNA
AW166_20000	COG1191	sigma factor activity
AW166_20025	COG1484	DNA-dependent DNA replication
AW166_20055	COG1396	sequence-specific DNA binding
AW166_20065	COG1396	sequence-specific DNA binding
AW166_20080	COG0582	viral genome integration into host DNA
AW166_20090	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW166_20095	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW166_20100	COG3314	Sporulation integral membrane protein YlbJ
AW166_20110	COG0742	ribosomal rna small subunit methyltransferase
AW166_20125	COG3679	Belongs to the UPF0342 family
AW166_20130	COG0406	alpha-ribazole phosphatase activity
AW166_20145	COG2340	Cysteine-rich secretory protein family
AW166_20160	COG3336	cytochrome c oxidase
AW166_20195	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW166_20200	COG0772	Belongs to the SEDS family
AW166_20205	COG4838	Belongs to the UPF0358 family
AW166_20210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW166_20215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW166_20225	COG4896	Protein conserved in bacteria
AW166_20250	COG0483	inositol monophosphate 1-phosphatase activity
AW166_20270	COG1982	Orn Lys Arg decarboxylase major
AW166_20315	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_20320	COG0022	dehydrogenase e1 component
AW166_20325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_20335	COG0242	peptide deformylase activity
AW166_20340	COG0561	phosphatase activity
AW166_20350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW166_20355	COG0569	domain protein
AW166_20375	COG0583	DNA-binding transcription factor activity
AW166_20380	COG0517	IMP dehydrogenase activity
AW166_20390	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW166_20400	COG4703	Protein of unknown function (DUF1797)
AW166_20415	COG2200	EAL domain
AW166_20420	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_20425	COG1408	metallophosphoesterase
AW166_20435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AW166_20475	COG2814	Major facilitator Superfamily
AW166_20495	COG3209	COG3209 Rhs family protein
AW166_20505	COG2205	protein histidine kinase activity
AW166_20515	COG0436	Aminotransferase
AW166_20520	COG1609	Transcriptional regulator
AW166_20525	COG3833	ABC-type maltose transport systems, permease component
AW166_20530	COG1175	transmembrane transport
AW166_20535	COG2182	Extracellular solute-binding protein
AW166_20545	COG0366	Alpha amylase catalytic
AW166_20550	COG3842	ATPase activity
AW166_20590	COG0183	Belongs to the thiolase family
AW166_20630	COG1695	Transcriptional regulator
AW166_20635	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_20655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW166_20660	COG0436	Aminotransferase
AW166_20680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW166_20700	COG3706	GGDEF domain
AW166_20705	COG0778	Nitroreductase
AW166_20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_20730	COG1263	PTS System
AW166_20730	COG2190	(PTS) system
AW166_20735	COG3711	transcriptional antiterminator
AW166_20755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW166_20785	COG1547	Domain of unknown function (DUF309)
AW166_20790	COG0456	acetyltransferase
AW166_20800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW166_20805	COG4086	secreted protein
AW166_20810	COG0561	phosphatase activity
AW166_20815	COG0697	spore germination
AW166_20830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_20855	COG0733	neurotransmitter:sodium symporter activity
AW166_20875	COG1686	Belongs to the peptidase S11 family
AW166_20880	COG1725	Transcriptional regulator
AW166_20885	COG1131	(ABC) transporter
AW166_20905	COG1846	Transcriptional regulator
AW166_20920	COG0598	Magnesium transport protein CorA
AW166_20945	COG4974	Belongs to the 'phage' integrase family
AW166_20955	COG0735	belongs to the Fur family
AW166_20960	COG1300	Membrane
AW166_20980	COG0667	Aldo Keto reductase
AW166_20985	COG0656	L-ascorbic acid biosynthetic process
AW166_20990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_20990	COG0456	acetyltransferase
AW166_21000	COG0737	Belongs to the 5'-nucleotidase family
AW166_21000	COG4085	toxin activity
AW166_21000	COG1525	nuclease
AW166_21010	COG0596	Alpha beta hydrolase
AW166_21015	COG2056	Na+-H+ antiporter family
AW166_21020	COG1609	Transcriptional regulator
AW166_21025	COG0456	acetyltransferase
AW166_21030	COG1073	alpha beta
AW166_21045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW166_21045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW166_21050	COG0307	riboflavin synthase, alpha
AW166_21070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AW166_21075	COG4106	trans-aconitate 2-methyltransferase activity
AW166_21080	COG2226	methyltransferase
AW166_21080	COG1073	alpha beta
AW166_21085	COG0156	8-amino-7-oxononanoate synthase activity
AW166_21095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_21110	COG0737	Belongs to the 5'-nucleotidase family
AW166_21120	COG1522	sequence-specific DNA binding
AW166_21140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW166_21150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW166_21165	COG0300	oxidoreductase activity
AW166_21170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_21180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_21185	COG1760	l-serine dehydratase
AW166_21190	COG1760	l-serine dehydratase
AW166_21210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW166_21220	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW166_21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_21240	COG1376	ErfK ybiS ycfS ynhG family protein
AW166_21245	COG4129	membrane
AW166_21250	COG1126	abc transporter atp-binding protein
AW166_21255	COG0765	amino acid transport
AW166_21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_21280	COG0772	Belongs to the SEDS family
AW166_21290	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_21295	COG0022	dehydrogenase e1 component
AW166_21300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_21305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW166_21315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW166_21320	COG0280	phosphate acetyltransferase
AW166_21330	COG3290	protein histidine kinase activity
AW166_21330	COG3829	transcription factor binding
AW166_21340	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_21345	COG3093	addiction module antidote protein HigA
AW166_21355	COG0745	RESPONSE REGULATOR receiver
AW166_21365	COG0750	zinc metalloprotease
AW166_21370	COG0497	DNA recombination
AW166_21380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW166_21390	COG0142	geranyltranstransferase activity
AW166_21415	COG1302	Protein conserved in bacteria
AW166_21420	COG0439	Biotin carboxylase
AW166_21425	COG0511	ligase activity, forming carbon-carbon bonds
AW166_21470	COG3854	ATPases associated with a variety of cellular activities
AW166_21495	COG0006	proline dipeptidase activity
AW166_21510	COG3872	metal-dependent enzyme
AW166_21520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW166_21540	COG0095	Lipoate-protein ligase
AW166_21545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_21550	COG1609	Transcriptional regulator
AW166_21560	COG2076	Multidrug Resistance protein
AW166_21565	COG2076	Multidrug Resistance protein
AW166_21605	COG1131	(ABC) transporter
AW166_21610	COG1725	Transcriptional regulator
AW166_21640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_21695	COG4970	Tfp pilus assembly protein FimT
AW166_21705	COG1459	type II secretion system
AW166_21710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW166_21760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW166_21765	COG0646	methionine synthase
AW166_21765	COG1410	methionine synthase
AW166_21770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW166_21770	COG0646	methionine synthase
AW166_21775	COG0626	cystathionine gamma-synthase activity
AW166_21780	COG0626	cystathionine gamma-synthase activity
AW166_21805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_21815	COG1940	carbohydrate kinase activity
AW166_21820	COG4483	Protein conserved in bacteria
AW166_21825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW166_21835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW166_21840	COG0704	Plays a role in the regulation of phosphate uptake
AW166_21845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW166_21850	COG0581	inorganic phosphate transmembrane transporter activity
AW166_21855	COG0573	inorganic phosphate transmembrane transporter activity
AW166_21860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW166_21870	COG0477	Major facilitator Superfamily
AW166_21875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_21900	COG0735	belongs to the Fur family
AW166_21905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW166_21910	COG1121	(ABC) transporter
AW166_21915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_21945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW166_21950	COG2384	SAM-dependent methyltransferase
AW166_21955	COG2010	Cytochrome c
AW166_21960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW166_21965	COG0358	DNA primase activity
AW166_21985	COG0517	IMP dehydrogenase activity
AW166_22000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW166_22005	COG0295	cytidine deaminase activity
AW166_22010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW166_22020	COG1480	7TM receptor with intracellular HD hydrolase
AW166_22025	COG1702	phosphate starvation-inducible protein PhoH
AW166_22045	COG1610	YqeY-like protein
AW166_22055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW166_22060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW166_22080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AW166_22090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW166_22095	COG1733	regulation of RNA biosynthetic process
AW166_22120	COG1466	dna polymerase III delta subunit
AW166_22130	COG0658	competence protein
AW166_22130	COG2333	competence protein COMEC
AW166_22135	COG2131	deaminase
AW166_22140	COG1596	polysaccharide export
AW166_22140	COG1555	photosystem II stabilization
AW166_22145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_22150	COG2226	methyltransferase
AW166_22155	COG0799	negative regulation of ribosome biogenesis
AW166_22160	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW166_22170	COG1534	Rna-binding protein
AW166_22180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW166_22185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW166_22200	COG1191	sigma factor activity
AW166_22210	COG1595	DNA-templated transcription, initiation
AW166_22220	COG0778	Nitroreductase
AW166_22225	COG2357	RelA SpoT domain protein
AW166_22235	COG1785	Belongs to the alkaline phosphatase family
AW166_22245	COG2267	carboxylic ester hydrolase activity
AW166_22280	COG1404	Belongs to the peptidase S8 family
AW166_22285	COG3186	Phenylalanine-4-hydroxylase
AW166_22295	COG2514	catechol 2,3-dioxygenase activity
AW166_22300	COG2514	catechol 2,3-dioxygenase activity
AW166_22305	COG2259	Doxx family
AW166_22345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_22355	COG1012	belongs to the aldehyde dehydrogenase family
AW166_22355	COG1454	alcohol dehydrogenase
AW166_22360	COG0626	cystathionine gamma-synthase activity
AW166_22365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_22390	COG0768	penicillin binding
AW166_22420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW166_22440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_22450	COG0628	permease
AW166_22470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW166_22480	COG0482	sulfurtransferase activity
AW166_22485	COG1104	cysteine desulfurase activity
AW166_22490	COG1959	2 iron, 2 sulfur cluster binding
AW166_22495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW166_22505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW166_22515	COG0124	histidyl-tRNA synthetase
AW166_22530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW166_22540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW166_22540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW166_22545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW166_22550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW166_22550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW166_22560	COG2244	polysaccharide biosynthetic process
AW166_22565	COG2323	membrane
AW166_22575	COG1862	Preprotein translocase
AW166_22605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW166_22615	COG0697	spore germination
AW166_22620	COG0697	spore germination
AW166_22625	COG0640	Transcriptional regulator
AW166_22650	COG0157	Belongs to the NadC ModD family
AW166_22655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW166_22660	COG1104	cysteine desulfurase activity
AW166_22665	COG1827	regulation of RNA biosynthetic process
AW166_22670	COG2258	MOSC domain
AW166_22675	COG0077	Prephenate dehydratase
AW166_22680	COG0577	efflux transmembrane transporter activity
AW166_22685	COG0577	efflux transmembrane transporter activity
AW166_22690	COG1136	(ABC) transporter
AW166_22695	COG5002	protein histidine kinase activity
AW166_22705	COG0745	RESPONSE REGULATOR receiver
AW166_22710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW166_22715	COG3290	protein histidine kinase activity
AW166_22725	COG2868	ribosomal protein
AW166_22735	COG1530	ribonuclease E activity
AW166_22740	COG1994	Peptidase M50
AW166_22745	COG0739	heme binding
AW166_22750	COG2894	cell division
AW166_22765	COG1792	Involved in formation and maintenance of cell shape
AW166_22770	COG1077	Cell shape determining protein MreB Mrl
AW166_22790	COG0285	dihydrofolate synthase activity
AW166_22795	COG0525	valine-tRNA ligase activity
AW166_22805	COG1388	LysM domain
AW166_22815	COG0113	porphobilinogen synthase activity
AW166_22820	COG1587	Uroporphyrinogen-III synthase
AW166_22830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW166_22840	COG1846	Transcriptional regulator
AW166_22845	COG1764	response to oxidative stress
AW166_22860	COG1067	ATP-dependent peptidase activity
AW166_22860	COG0470	DNA polymerase III
AW166_22915	COG0622	Phosphoesterase
AW166_22920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AW166_22930	COG5401	PFAM Sporulation and spore germination
AW166_22950	COG1309	transcriptional regulator
AW166_22965	COG2197	response regulator
AW166_22970	COG2233	PERMEase
AW166_22980	COG0402	S-adenosylhomocysteine deaminase activity
AW166_22985	COG0402	S-adenosylhomocysteine deaminase activity
AW166_23005	COG0444	Belongs to the ABC transporter superfamily
AW166_23010	COG4608	Belongs to the ABC transporter superfamily
AW166_23015	COG3275	phosphorelay sensor kinase activity
AW166_23020	COG3279	Response regulator of the LytR AlgR family
AW166_23035	COG1983	PspC domain protein
AW166_23040	COG1396	sequence-specific DNA binding
AW166_23045	COG0697	spore germination
AW166_23055	COG1959	2 iron, 2 sulfur cluster binding
AW166_23060	COG1668	transmembrane transport
AW166_23065	COG4152	abc transporter atp-binding protein
AW166_23070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AW166_23080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW166_23085	COG1876	peptidase activity
AW166_23090	COG0824	Thioesterase
AW166_23095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW166_23100	COG1053	succinate dehydrogenase
AW166_23105	COG2009	succinate dehydrogenase
AW166_23110	COG1719	4-vinyl reductase, 4VR
AW166_23120	COG3118	belongs to the thioredoxin family
AW166_23125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW166_23130	COG2086	electron transfer activity
AW166_23135	COG1024	Enoyl-CoA hydratase
AW166_23140	COG1309	transcriptional regulator
AW166_23145	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_23165	COG2318	DinB family
AW166_23195	COG1131	(ABC) transporter
AW166_23200	COG2205	protein histidine kinase activity
AW166_23205	COG0745	RESPONSE REGULATOR receiver
AW166_23215	COG4895	conserved protein (DUF2196)
AW166_23220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW166_23235	COG4509	Sortase family
AW166_23240	COG1120	ATPase activity
AW166_23255	COG5386	Cell surface protein
AW166_23265	COG5386	Cell surface protein
AW166_23270	COG1114	Component of the transport system for branched-chain amino acids
AW166_23275	COG1187	pseudouridine synthase activity
AW166_23290	COG1796	DNA polymerase
AW166_23290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW166_23295	COG1286	toxin biosynthetic process
AW166_23325	COG0017	Asparaginyl-tRNA synthetase
AW166_23330	COG0072	phenylalanine-tRNA ligase activity
AW166_23330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_23340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW166_23350	COG1418	mRNA catabolic process
AW166_23375	COG2814	Major facilitator Superfamily
AW166_23380	COG1566	PFAM secretion protein HlyD family protein
AW166_23385	COG1309	transcriptional regulator
AW166_23390	COG1363	Peptidase, m42
AW166_23410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AW166_23415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_23425	COG1484	DNA-dependent DNA replication
AW166_23430	COG3611	Membrane attachment protein
AW166_23440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW166_23445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW166_23450	COG0237	dephospho-CoA kinase activity
AW166_23455	COG1971	Probably functions as a manganese efflux pump
AW166_23460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AW166_23465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_23465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_23470	COG5002	protein histidine kinase activity
AW166_23475	COG0745	RESPONSE REGULATOR receiver
AW166_23495	COG0538	isocitrate dehydrogenase activity
AW166_23500	COG0372	Belongs to the citrate synthase family
AW166_23515	COG0628	permease
AW166_23520	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW166_23545	COG1725	Transcriptional regulator
AW166_23550	COG0281	malic enzyme
AW166_23555	COG0587	DNA-directed DNA polymerase activity
AW166_23570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW166_23590	COG4109	DRTGG domain
AW166_23605	COG0006	proline dipeptidase activity
AW166_23640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_23645	COG0662	Cupin 2, conserved barrel domain protein
AW166_23655	COG1476	TRANSCRIPTIONal
AW166_23670	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_23675	COG0589	response to stress
AW166_23715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_23735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW166_23740	COG0827	DNA restriction-modification system
AW166_23745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW166_23750	COG3874	Sporulation protein YtfJ
AW166_23760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW166_23765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW166_23775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_23790	COG1104	cysteine desulfurase activity
AW166_23800	COG0583	DNA-binding transcription factor activity
AW166_23805	COG0697	spore germination
AW166_23815	COG1956	GAF domain-containing protein
AW166_23820	COG0626	cystathionine gamma-synthase activity
AW166_23840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW166_23850	COG1595	DNA-templated transcription, initiation
AW166_23860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_23865	COG0454	-acetyltransferase
AW166_23870	COG0517	IMP dehydrogenase activity
AW166_23875	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW166_23885	COG0745	RESPONSE REGULATOR receiver
AW166_23895	COG0666	response to abiotic stimulus
AW166_23930	COG1609	Transcriptional regulator
AW166_23940	COG4851	CamS sex pheromone cAM373 precursor
AW166_23945	COG3118	belongs to the thioredoxin family
AW166_23955	COG2309	aminopeptidase activity
AW166_23975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_23990	COG1674	ftsk spoiiie
AW166_24000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_24005	COG4848	Belongs to the UPF0354 family
AW166_24010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_24015	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AW166_24020	COG1363	Peptidase, m42
AW166_24030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_24045	COG0510	thiamine kinase activity
AW166_24050	COG1523	belongs to the glycosyl hydrolase 13 family
AW166_24065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_24070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_24075	COG1349	DNA-binding transcription factor activity
AW166_24080	COG1187	pseudouridine synthase activity
AW166_24085	COG2244	polysaccharide biosynthetic process
AW166_24090	COG2081	HI0933 family
AW166_24095	COG2814	Major facilitator Superfamily
AW166_24105	COG3832	glyoxalase III activity
AW166_24125	COG1329	Transcriptional regulator
AW166_24135	COG4975	Glucose uptake
AW166_24150	COG0314	molybdopterin synthase activity
AW166_24155	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW166_24160	COG0303	'Molybdopterin
AW166_24170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_24195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_24205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AW166_24250	COG2814	Major facilitator Superfamily
AW166_24255	COG0475	glutathione-regulated potassium exporter activity
AW166_24260	COG0490	domain, Protein
AW166_24265	COG0582	viral genome integration into host DNA
AW166_24275	COG1136	(ABC) transporter
AW166_24295	COG1242	4 iron, 4 sulfur cluster binding
AW166_24300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW166_24305	COG1131	(ABC) transporter
AW166_24315	COG1794	racemase activity, acting on amino acids and derivatives
AW166_24335	COG2267	carboxylic ester hydrolase activity
AW166_24340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW166_24345	COG0671	phosphoesterase, PA-phosphatase related
AW166_24350	COG0438	transferase activity, transferring glycosyl groups
AW166_24360	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW166_24415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW166_24420	COG5002	protein histidine kinase activity
AW166_24425	COG4191	Histidine kinase
AW166_24430	COG2267	carboxylic ester hydrolase activity
AW166_24450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_24455	COG1116	anion transmembrane transporter activity
AW166_24460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_24485	COG0494	nUDIX hydrolase
AW166_24515	COG0288	reversible hydration of carbon dioxide
AW166_24520	COG1271	oxidase subunit
AW166_24525	COG1294	oxidase, subunit
AW166_24545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_24570	COG1842	Phage shock protein A
AW166_24605	COG5002	protein histidine kinase activity
AW166_24610	COG0745	RESPONSE REGULATOR receiver
AW166_24640	COG1597	lipid kinase activity
AW166_24675	COG0586	Pfam SNARE associated Golgi protein
AW166_24685	COG0577	efflux transmembrane transporter activity
AW166_24690	COG1136	(ABC) transporter
AW166_24695	COG2207	Transcriptional regulator
AW166_24695	COG3708	Transcriptional regulator
AW166_24700	COG0745	RESPONSE REGULATOR receiver
AW166_24705	COG2205	protein histidine kinase activity
AW166_24710	COG0577	efflux transmembrane transporter activity
AW166_24720	COG0577	efflux transmembrane transporter activity
AW166_24725	COG1136	(ABC) transporter
AW166_24765	COG3964	amidohydrolase
AW166_24795	COG4948	Mandelate Racemase Muconate Lactonizing
AW166_24805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW166_24810	COG0596	Alpha beta hydrolase
AW166_24815	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW166_24820	COG1169	isochorismate synthase
AW166_24825	COG1575	Belongs to the MenA family. Type 1 subfamily
AW166_24830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW166_24835	COG1278	Cold shock
AW166_24855	COG0058	SHG alpha-glucan phosphorylase activity
AW166_24860	COG0297	glycogen (starch) synthase activity
AW166_24865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW166_24870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW166_24880	COG0039	L-malate dehydrogenase activity
AW166_24975	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW166_25010	COG1285	pathogenesis
AW166_25015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW166_25025	COG0166	Belongs to the GPI family
AW166_25035	COG2155	Conserved Protein
AW166_25040	COG1098	S1 RNA binding domain
AW166_25045	COG0436	Aminotransferase
AW166_25050	COG1522	sequence-specific DNA binding
AW166_25055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW166_25060	COG2267	carboxylic ester hydrolase activity
AW166_25070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW166_25090	COG5018	Exonuclease
AW166_25095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_25110	COG0423	glycine-tRNA ligase activity
AW166_25115	COG2050	protein possibly involved in aromatic compounds catabolism
AW166_25125	COG1268	BioY protein
AW166_25135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW166_25140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW166_25155	COG3584	3D domain protein
AW166_25170	COG1252	NADH dehydrogenase
AW166_25185	COG3708	Transcriptional regulator
AW166_25200	COG1683	Conserved Protein
AW166_25220	COG0316	Belongs to the HesB IscA family
AW166_25235	COG1252	NADH dehydrogenase
AW166_25250	COG0390	transport system, permease component
AW166_25255	COG2824	Alkylphosphonate utilization operon protein PhnA
AW166_25295	COG4837	Protein of unknown function (DUF1462)
AW166_25300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW166_25310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_25315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW166_25330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_25335	COG0647	UMP catabolic process
AW166_25345	COG2445	Protein of unknown function DUF86
AW166_25350	COG1494	fructose-1,6-bisphosphatase
AW166_25370	COG4470	Protein conserved in bacteria
AW166_25380	COG0789	Transcriptional regulator
AW166_25385	COG4377	Putative membrane peptidase family (DUF2324)
AW166_25410	COG0739	heme binding
AW166_25420	COG3377	Domain of unknown function (DUF1805)
AW166_25425	COG0737	Belongs to the 5'-nucleotidase family
AW166_25435	COG1695	Transcriptional regulator
AW166_25450	COG0719	Fe-S assembly protein
AW166_25455	COG0822	iron-sulfur transferase activity
AW166_25460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW166_25465	COG0719	Fe-S assembly protein
AW166_25470	COG0396	ATPase activity
AW166_25475	COG1464	Belongs to the NlpA lipoprotein family
AW166_25480	COG1464	Belongs to the NlpA lipoprotein family
AW166_25485	COG2011	ABC-type metal ion transport system permease component
AW166_25490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_25505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_25510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW166_25520	COG1393	Belongs to the ArsC family
AW166_25570	COG0039	L-malate dehydrogenase activity
AW166_25590	COG1309	transcriptional regulator
AW166_25595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_25600	COG1960	acyl-CoA dehydrogenase activity
AW166_25610	COG0183	Belongs to the thiolase family
AW166_25615	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW166_25615	COG1024	Enoyl-CoA hydratase
AW166_25625	COG1686	Belongs to the peptidase S11 family
AW166_25640	COG0011	TIGRFAM Protein of
AW166_25645	COG0840	transmembrane signaling receptor activity
AW166_25665	COG2814	Major facilitator Superfamily
AW166_25670	COG0531	amino acid
AW166_25680	COG0706	membrane insertase activity
AW166_25690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_25725	COG0586	Pfam SNARE associated Golgi protein
AW166_25735	COG1376	ErfK ybiS ycfS ynhG family protein
AW166_25740	COG0745	RESPONSE REGULATOR receiver
AW166_25745	COG5002	protein histidine kinase activity
AW166_25755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_25770	COG2151	metal-sulfur cluster biosynthetic enzyme
AW166_25775	COG3227	Zinc metalloprotease (Elastase)
AW166_25780	COG1741	Belongs to the pirin family
AW166_25795	COG0475	glutathione-regulated potassium exporter activity
AW166_25800	COG0490	domain, Protein
AW166_25810	COG1115	amino acid carrier protein
AW166_25815	COG0783	Belongs to the Dps family
AW166_25830	COG1611	Belongs to the LOG family
AW166_25845	COG2311	Membrane
AW166_25855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_25860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_25865	COG1115	amino acid carrier protein
AW166_25870	COG1115	amino acid carrier protein
AW166_25875	COG2910	NAD(P)H-binding
AW166_25890	COG0656	L-ascorbic acid biosynthetic process
AW166_25895	COG2814	Major facilitator Superfamily
AW166_25900	COG1733	regulation of RNA biosynthetic process
AW166_25910	COG1252	NADH dehydrogenase
AW166_25915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW166_25920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW166_25930	COG0840	transmembrane signaling receptor activity
AW166_25930	COG3290	protein histidine kinase activity
AW166_25940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW166_25945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW166_25960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_25965	COG3223	Belongs to the PsiE family
AW166_26015	COG0557	exoribonuclease II activity
AW166_26020	COG1647	Serine aminopeptidase, S33
AW166_26025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW166_26030	COG1346	cytolysis
AW166_26130	COG4695	Portal protein
AW166_26155	COG4974	Belongs to the 'phage' integrase family
AW166_26165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW166_26170	COG0149	triose-phosphate isomerase activity
AW166_26180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW166_26195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW166_26220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_26235	COG2323	membrane
AW166_26240	COG0740	serine-type endopeptidase activity
AW166_26245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_26255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW166_26265	COG1051	belongs to the nudix hydrolase family
AW166_26275	COG0492	ferredoxin-NADP+ reductase activity
AW166_26280	COG0457	Tetratricopeptide repeat
AW166_26285	COG0110	maltose O-acetyltransferase activity
AW166_26305	COG1950	PFAM Membrane protein of
AW166_26315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_26320	COG0556	nucleotide-excision repair
AW166_26340	COG0789	Transcriptional regulator
AW166_26365	COG2855	membrane
AW166_26370	COG0583	DNA-binding transcription factor activity
AW166_26380	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW166_26395	COG1132	(ABC) transporter
AW166_26400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_26405	COG0793	Belongs to the peptidase S41A family
AW166_26405	COG3409	Peptidoglycan-binding domain 1 protein
AW166_26410	COG2177	Part of the ABC transporter FtsEX involved in
AW166_26415	COG2884	Cell division ATP-binding protein ftsE
AW166_26430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW166_26435	COG0653	protein targeting
AW166_26440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW166_26445	COG1278	Cold shock
AW166_26450	COG1040	competence protein
AW166_26455	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW166_26460	COG1388	LysM domain
AW166_26460	COG0791	NLP P60 protein
AW166_26465	COG1733	regulation of RNA biosynthetic process
AW166_26475	COG1307	EDD domain protein, DegV family
AW166_26480	COG1739	Uncharacterized protein family UPF0029
AW166_26485	COG1316	TRANSCRIPTIONal
AW166_26490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW166_26495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW166_26500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW166_26510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW166_26510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW166_26525	COG3394	polysaccharide catabolic process
AW166_26530	COG1486	melibiose metabolic process
AW166_26535	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_26540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_26550	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW166_26555	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW166_26560	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_26570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_26575	COG1301	dicarboxylic acid transport
AW166_26585	COG0346	lactoylglutathione lyase activity
AW166_26590	COG1511	domain protein
AW166_26595	COG0583	DNA-binding transcription factor activity
AW166_26600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW166_26620	COG1271	oxidase subunit
AW166_26625	COG1294	oxidase, subunit
AW166_26630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_26640	COG1620	l-lactate permease
AW166_26650	COG2389	metal-binding protein
AW166_26660	COG1368	sulfuric ester hydrolase activity
AW166_26675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_26695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_26700	COG3584	3D domain protein
AW166_26700	COG1388	LysM domain
AW166_26725	COG4715	Zinc finger, swim domain protein
AW166_26730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_26760	COG1191	sigma factor activity
AW166_26770	COG0577	efflux transmembrane transporter activity
AW166_26775	COG1136	(ABC) transporter
AW166_26810	COG5002	protein histidine kinase activity
AW166_26815	COG0745	RESPONSE REGULATOR receiver
AW166_26820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW166_26835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW166_26840	COG1134	teichoic acid transport
AW166_26845	COG1682	transport, permease protein
AW166_26850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW166_26895	COG1609	Transcriptional regulator
AW166_26910	COG0739	heme binding
AW166_26925	COG3279	Response regulator of the LytR AlgR family
AW166_26930	COG4555	ABC transporter
AW166_26935	COG2385	sporulation resulting in formation of a cellular spore
AW166_26940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW166_26950	COG4836	Membrane
AW166_26955	COG1007	ATP synthesis coupled electron transport
AW166_26960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW166_26965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW166_26975	COG0839	Belongs to the complex I subunit 6 family
AW166_26990	COG0649	NAD binding
AW166_26995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW166_27005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW166_27010	COG3300	MHYT domain
AW166_27010	COG5001	Diguanylate cyclase
AW166_27060	COG0356	it plays a direct role in the translocation of protons across the membrane
AW166_27095	COG0698	ribose 5-phosphate isomerase
AW166_27105	COG2190	(PTS) system
AW166_27110	COG2259	Doxx family
AW166_27115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW166_27130	COG0009	L-threonylcarbamoyladenylate synthase
AW166_27145	COG2890	protein-(glutamine-N5) methyltransferase activity
AW166_27150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AW166_27165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW166_27170	COG1494	fructose-1,6-bisphosphatase
AW166_27175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW166_27190	COG4821	SIS domain
AW166_27200	COG3343	RNA polymerase activity
AW166_27210	COG1960	acyl-CoA dehydrogenase activity
AW166_27215	COG1960	acyl-CoA dehydrogenase activity
AW166_27220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW166_27225	COG0183	Belongs to the thiolase family
AW166_27230	COG0247	lactate metabolic process
AW166_27230	COG2181	nitrate reductase activity
AW166_27235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_27245	COG5001	Diguanylate cyclase
AW166_27245	COG3300	MHYT domain
AW166_27260	COG2197	response regulator
AW166_27265	COG4585	Histidine kinase
AW166_27270	COG0842	Transport permease protein
AW166_27275	COG1131	(ABC) transporter
AW166_27280	COG0024	Methionine aminopeptidase
AW166_27300	COG2234	aminopeptidase activity
AW166_27320	COG1595	DNA-templated transcription, initiation
AW166_27325	COG0018	arginyl-trna synthetase
AW166_27330	COG4506	Protein conserved in bacteria
AW166_27335	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_27355	COG0010	Belongs to the arginase family
AW166_27360	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW166_27365	COG2814	Major facilitator Superfamily
AW166_27370	COG0789	Transcriptional regulator
AW166_27375	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_27380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_27390	COG1994	Peptidase M50
AW166_27400	COG1078	dGTPase activity
AW166_27405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_27410	COG1120	ATPase activity
AW166_27415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_27420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_27425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_27445	COG0095	Lipoate-protein ligase
AW166_27450	COG0280	phosphate acetyltransferase
AW166_27465	COG3773	Cell wall hydrolase
AW166_27475	COG2363	Small membrane protein
AW166_27490	COG2233	PERMEase
AW166_27495	COG0561	phosphatase activity
AW166_27500	COG2814	Major facilitator Superfamily
AW166_27510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_27515	COG1131	(ABC) transporter
AW166_27520	COG2755	lipolytic protein G-D-S-L family
AW166_27525	COG1609	Transcriptional regulator
AW166_27535	COG0460	homoserine dehydrogenase
AW166_27555	COG1011	Hydrolase
AW166_27560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW166_27570	COG2197	response regulator
AW166_27580	COG0351	phosphomethylpyrimidine kinase
AW166_27585	COG3706	GGDEF domain
AW166_27590	COG2879	small protein
AW166_27595	COG1966	Carbon starvation protein
AW166_27600	COG3279	Response regulator of the LytR AlgR family
AW166_27605	COG0477	Major facilitator Superfamily
AW166_27630	COG0840	transmembrane signaling receptor activity
AW166_27640	COG1607	acyl-coa hydrolase
AW166_27655	COG0488	(ABC) transporter
AW166_27680	COG0463	Glycosyl transferase, family 2
AW166_27685	COG1309	transcriptional regulator
AW166_27690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW166_27695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_27695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_27700	COG0628	permease
AW166_27715	COG3279	Response regulator of the LytR AlgR family
AW166_27720	COG3275	phosphorelay sensor kinase activity
AW166_27725	COG2814	Major facilitator Superfamily
AW166_27730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_27735	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW166_27745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_27765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW166_27770	COG1272	protein, Hemolysin III
AW166_27790	COG0516	GMP reductase activity
AW166_27795	COG1164	Oligoendopeptidase f
AW166_27815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_27820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW166_27825	COG4853	Protein conserved in bacteria
AW166_27830	COG4863	YycH protein
AW166_27835	COG5002	protein histidine kinase activity
AW166_27840	COG0745	RESPONSE REGULATOR receiver
AW166_27870	COG0305	Participates in initiation and elongation during chromosome replication
AW166_27880	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW166_27885	COG4241	membrane
AW166_27895	COG0629	single-stranded DNA binding
AW166_27905	COG0012	GTP binding
AW166_27910	COG4481	Protein conserved in bacteria
AW166_27915	COG0668	transmembrane transport
AW166_27925	COG1475	DNA binding
AW166_27930	COG1192	Involved in chromosome partitioning
AW166_27950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AW166_27955	COG1847	R3H domain protein
AW166_27960	COG0706	membrane insertase activity
AW166_28015	COG3344	reverse transcriptase
AW166_28095	COG3344	reverse transcriptase
AW166_28305	COG4962	Type ii secretion system protein e
AW166_28440	COG2311	Membrane
AW166_28465	COG4196	transglutaminase domain protein
AW166_28470	COG0671	phosphoesterase, PA-phosphatase related
AW166_28495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW166_28500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW166_28515	COG2801	Transposase and inactivated derivatives
AW166_28670	COG2002	toxin-antitoxin pair type II binding
AW166_28680	COG4974	Belongs to the 'phage' integrase family
AW166_28720	COG2801	Transposase and inactivated derivatives
AW166_28740	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW166_28750	COG4974	Belongs to the 'phage' integrase family
AW166_28775	COG0457	Tetratricopeptide repeat
AW166_28780	COG1923	regulation of RNA biosynthetic process
AW166_28860	COG0791	NLP P60 protein
AW166_28860	COG0741	lytic transglycosylase activity
AW166_29005	COG1192	Involved in chromosome partitioning
AW166_29025	COG2801	Transposase and inactivated derivatives
AW166_29050	COG1683	Conserved Protein
AW166_29055	COG1309	transcriptional regulator
AW166_29125	COG0681	Belongs to the peptidase S26 family
AW166_29155	COG1280	lysine exporter protein (LysE YggA)
AW166_29190	COG4166	transmembrane transport
AW166_29205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW166_29265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW166_29270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone