locus-tag	class	description
A8C77_00010	COG0592	DNA-directed DNA polymerase activity
A8C77_00015	COG2501	S4 domain
A8C77_00025	COG0187	DNA topoisomerase II activity
A8C77_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A8C77_00065	COG0516	GMP reductase activity
A8C77_00065	COG0517	IMP dehydrogenase activity
A8C77_00070	COG1686	Belongs to the peptidase S11 family
A8C77_00100	COG1428	Deoxynucleoside kinase
A8C77_00105	COG1428	Deoxynucleoside kinase
A8C77_00110	COG1335	isochorismatase
A8C77_00120	COG0590	tRNA wobble adenosine to inosine editing
A8C77_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A8C77_00185	COG1982	Orn Lys Arg decarboxylase major
A8C77_00195	COG0470	DNA polymerase III
A8C77_00200	COG1774	PSP1 C-terminal conserved region
A8C77_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A8C77_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A8C77_00225	COG2002	toxin-antitoxin pair type II binding
A8C77_00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_00235	COG0084	hydrolase, TatD family'
A8C77_00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A8C77_00255	COG4466	Protein conserved in bacteria
A8C77_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A8C77_00275	COG0251	oxidation-reduction process
A8C77_00290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A8C77_00295	COG0193	aminoacyl-tRNA hydrolase activity
A8C77_00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8C77_00310	COG2002	toxin-antitoxin pair type II binding
A8C77_00315	COG2244	polysaccharide biosynthetic process
A8C77_00320	COG3956	TIGRFAM MazG family protein
A8C77_00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8C77_00345	COG1098	S1 RNA binding domain
A8C77_00360	COG2208	phosphoserine phosphatase activity
A8C77_00365	COG0037	tRNA processing
A8C77_00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A8C77_00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8C77_00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A8C77_00400	COG0512	Glutamine amidotransferase of anthranilate synthase
A8C77_00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C77_00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A8C77_00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8C77_00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8C77_00425	COG1396	sequence-specific DNA binding
A8C77_00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C77_00460	COG3880	PFAM UvrB UvrC protein
A8C77_00470	COG0542	response to heat
A8C77_00475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A8C77_00485	COG4956	integral membrane protein (PIN domain superfamily)
A8C77_00505	COG1045	serine acetyltransferase
A8C77_00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C77_00525	COG3688	RNA-binding protein containing a PIN domain
A8C77_00535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A8C77_00540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8C77_00545	COG0250	Participates in transcription elongation, termination and antitermination
A8C77_00570	COG2813	Specifically methylates the guanine in position
A8C77_00580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A8C77_00585	COG1358	cellular component organization or biogenesis
A8C77_00690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A8C77_00715	COG0201	protein transport
A8C77_00725	COG0024	Methionine aminopeptidase
A8C77_00735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A8C77_00765	COG1122	ATPase activity
A8C77_00770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A8C77_00775	COG0101	tRNA pseudouridine synthase activity
A8C77_00795	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C77_00800	COG0489	protein tyrosine kinase activity
A8C77_00810	COG2194	sulfuric ester hydrolase activity
A8C77_00815	COG0726	polysaccharide deacetylase
A8C77_00900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A8C77_00905	COG4856	YbbR-like protein
A8C77_00920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8C77_00925	COG0596	Alpha beta hydrolase
A8C77_00945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A8C77_00950	COG4946	Tricorn protease homolog
A8C77_00950	COG1506	peptidase
A8C77_00950	COG0823	Involved in the tonB-independent uptake of proteins
A8C77_00985	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_00990	COG2011	ABC-type metal ion transport system permease component
A8C77_00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8C77_01000	COG1464	Belongs to the NlpA lipoprotein family
A8C77_01015	COG0277	FAD linked oxidase domain protein
A8C77_01020	COG2271	Major facilitator Superfamily
A8C77_01030	COG2814	Major facilitator Superfamily
A8C77_01045	COG0601	transmembrane transport
A8C77_01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C77_01055	COG0444	Belongs to the ABC transporter superfamily
A8C77_01060	COG4608	Belongs to the ABC transporter superfamily
A8C77_01065	COG4166	transmembrane transport
A8C77_01075	COG2207	Transcriptional regulator
A8C77_01090	COG4166	transmembrane transport
A8C77_01095	COG4166	transmembrane transport
A8C77_01100	COG0656	L-ascorbic acid biosynthetic process
A8C77_01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C77_01125	COG4149	molybdate abc transporter
A8C77_01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8C77_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8C77_01140	COG1910	domain protein
A8C77_01155	COG0583	DNA-binding transcription factor activity
A8C77_01160	COG0697	spore germination
A8C77_01170	COG0204	Acyl-transferase
A8C77_01180	COG1609	Transcriptional regulator
A8C77_01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_01205	COG0084	hydrolase, TatD family'
A8C77_01210	COG5298	Protein conserved in bacteria
A8C77_01235	COG0488	(ABC) transporter
A8C77_01245	COG0747	negative chemotaxis
A8C77_01250	COG0601	transmembrane transport
A8C77_01260	COG0444	Belongs to the ABC transporter superfamily
A8C77_01265	COG4608	Belongs to the ABC transporter superfamily
A8C77_01290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A8C77_01295	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C77_01305	COG2814	Major facilitator Superfamily
A8C77_01320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8C77_01330	COG4294	response to UV
A8C77_01335	COG0705	Rhomboid family
A8C77_01335	COG0457	Tetratricopeptide repeat
A8C77_01345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A8C77_01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A8C77_01355	COG0864	Transcriptional regulator
A8C77_01360	COG2337	Toxic component of a toxin-antitoxin (TA) module
A8C77_01365	COG2183	response to ionizing radiation
A8C77_01460	COG0802	atpase or kinase
A8C77_01465	COG1214	PFAM Peptidase M22, glycoprotease
A8C77_01470	COG0456	acetyltransferase
A8C77_01475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A8C77_01480	COG0488	(ABC) transporter
A8C77_01495	COG1266	CAAX protease self-immunity
A8C77_01515	COG2252	PERMEase
A8C77_01525	COG5002	protein histidine kinase activity
A8C77_01555	COG2226	methyltransferase
A8C77_01595	COG1968	undecaprenyl-diphosphatase activity
A8C77_01610	COG2205	protein histidine kinase activity
A8C77_01615	COG0745	RESPONSE REGULATOR receiver
A8C77_01635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A8C77_01640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8C77_01645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8C77_01655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8C77_01670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A8C77_01680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8C77_01690	COG0151	Belongs to the GarS family
A8C77_01715	COG0210	DNA helicase
A8C77_01725	COG4851	CamS sex pheromone cAM373 precursor
A8C77_01745	COG1335	isochorismatase
A8C77_01750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8C77_01755	COG2011	ABC-type metal ion transport system permease component
A8C77_01760	COG1464	Belongs to the NlpA lipoprotein family
A8C77_01780	COG1846	Transcriptional regulator
A8C77_01805	COG1597	lipid kinase activity
A8C77_01810	COG0546	phosphoglycolate phosphatase activity
A8C77_01815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C77_01825	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_01830	COG2076	Multidrug Resistance protein
A8C77_01835	COG2309	aminopeptidase activity
A8C77_01850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_01855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8C77_01860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C77_01870	COG4807	Protein conserved in bacteria
A8C77_01900	COG1473	amidohydrolase
A8C77_01915	COG0450	alkyl hydroperoxide reductase
A8C77_01920	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A8C77_01930	COG0235	Class ii aldolase
A8C77_01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_01940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_01945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_01965	COG0166	Belongs to the GPI family
A8C77_02000	COG5002	protein histidine kinase activity
A8C77_02020	COG3541	Predicted nucleotidyltransferase
A8C77_02025	COG2814	Major facilitator Superfamily
A8C77_02030	COG0723	plastoquinol--plastocyanin reductase activity
A8C77_02030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C77_02040	COG0765	amino acid transport
A8C77_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C77_02060	COG0840	transmembrane signaling receptor activity
A8C77_02065	COG0840	transmembrane signaling receptor activity
A8C77_02070	COG0366	Alpha amylase catalytic
A8C77_02075	COG1263	PTS System
A8C77_02075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_02075	COG2190	(PTS) system
A8C77_02105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8C77_02120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C77_02130	COG1116	anion transmembrane transporter activity
A8C77_02135	COG0488	(ABC) transporter
A8C77_02180	COG2270	Major facilitator Superfamily
A8C77_02195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A8C77_02210	COG2310	stress, protein
A8C77_02215	COG2310	stress, protein
A8C77_02220	COG2310	stress, protein
A8C77_02225	COG0861	Integral membrane protein TerC family
A8C77_02235	COG3853	Toxic anion resistance protein (TelA)
A8C77_02250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A8C77_02260	COG1295	ribonuclease BN
A8C77_02265	COG2217	Heavy metal translocating P-type atpase
A8C77_02270	COG0697	spore germination
A8C77_02290	COG0586	Pfam SNARE associated Golgi protein
A8C77_02305	COG3871	stress protein (general stress protein 26)
A8C77_02310	COG0387	Pfam Sodium calcium exchanger
A8C77_02320	COG0535	radical SAM domain protein
A8C77_02345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8C77_02350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A8C77_02355	COG0582	viral genome integration into host DNA
A8C77_02360	COG1396	sequence-specific DNA binding
A8C77_02375	COG1396	sequence-specific DNA binding
A8C77_02410	COG1484	DNA-dependent DNA replication
A8C77_02505	COG0582	viral genome integration into host DNA
A8C77_02510	COG0582	viral genome integration into host DNA
A8C77_02635	COG0101	tRNA pseudouridine synthase activity
A8C77_02645	COG3829	transcription factor binding
A8C77_02655	COG0833	amino acid
A8C77_02660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8C77_02690	COG2066	Belongs to the glutaminase family
A8C77_02695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_02695	COG1263	PTS System
A8C77_02700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C77_02715	COG0463	Glycosyl transferase, family 2
A8C77_02730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A8C77_02730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C77_02750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C77_02770	COG1228	amidohydrolase
A8C77_02775	COG1090	epimerase
A8C77_02805	COG1988	membrane-bound metal-dependent
A8C77_02810	COG1194	a g-specific adenine glycosylase
A8C77_02835	COG1132	(ABC) transporter
A8C77_02840	COG4129	membrane
A8C77_02845	COG0070	glutamate synthase
A8C77_02845	COG0069	glutamate synthase activity
A8C77_02845	COG0067	glutamate synthase
A8C77_02855	COG4555	ABC transporter
A8C77_02875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8C77_02880	COG0735	belongs to the Fur family
A8C77_02995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A8C77_03000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8C77_03010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A8C77_03020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8C77_03035	COG2766	serine protein kinase
A8C77_03060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C77_03070	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8C77_03075	COG2268	Band 7 protein
A8C77_03085	COG3290	protein histidine kinase activity
A8C77_03095	COG2851	Citrate transporter
A8C77_03115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A8C77_03120	COG3842	ATPase activity
A8C77_03125	COG1175	transmembrane transport
A8C77_03130	COG0395	ABC-type sugar transport system, permease component
A8C77_03140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A8C77_03145	COG0745	RESPONSE REGULATOR receiver
A8C77_03150	COG5002	protein histidine kinase activity
A8C77_03160	COG4990	cell redox homeostasis
A8C77_03170	COG3290	protein histidine kinase activity
A8C77_03175	COG4565	transcriptional regulatory protein
A8C77_03180	COG3493	citrate carrier protein
A8C77_03185	COG0281	malic enzyme
A8C77_03200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_03210	COG5002	protein histidine kinase activity
A8C77_03215	COG0745	RESPONSE REGULATOR receiver
A8C77_03225	COG0454	-acetyltransferase
A8C77_03225	COG0456	acetyltransferase
A8C77_03230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A8C77_03235	COG3383	formate dehydrogenase (NAD+) activity
A8C77_03240	COG2427	Protein of unknown function (DUF1641)
A8C77_03255	COG0531	amino acid
A8C77_03260	COG0640	Transcriptional regulator
A8C77_03265	COG2217	Heavy metal translocating P-type atpase
A8C77_03270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A8C77_03280	COG3227	Zinc metalloprotease (Elastase)
A8C77_03300	COG2720	vancomycin resistance protein
A8C77_03305	COG1316	TRANSCRIPTIONal
A8C77_03310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_03315	COG0346	lactoylglutathione lyase activity
A8C77_03320	COG1253	flavin adenine dinucleotide binding
A8C77_03325	COG1027	Aspartate ammonia-lyase
A8C77_03330	COG1620	l-lactate permease
A8C77_03345	COG3104	oligopeptide transport
A8C77_03350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_03355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_03360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_03370	COG2226	methyltransferase
A8C77_03375	COG0156	8-amino-7-oxononanoate synthase activity
A8C77_03380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C77_03390	COG4548	von Willebrand factor, type A
A8C77_03395	COG0714	Associated with various cellular activities
A8C77_03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C77_03420	COG0531	amino acid
A8C77_03425	COG2188	Transcriptional regulator
A8C77_03430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_03430	COG1263	PTS System
A8C77_03435	COG0366	Alpha amylase catalytic
A8C77_03450	COG0697	spore germination
A8C77_03460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8C77_03465	COG1115	amino acid carrier protein
A8C77_03470	COG1126	abc transporter atp-binding protein
A8C77_03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C77_03480	COG0765	amino acid transport
A8C77_03485	COG0765	amino acid transport
A8C77_03490	COG0833	amino acid
A8C77_03515	COG2378	regulation of single-species biofilm formation
A8C77_03520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A8C77_03525	COG5002	protein histidine kinase activity
A8C77_03540	COG0659	secondary active sulfate transmembrane transporter activity
A8C77_03555	COG0747	negative chemotaxis
A8C77_03565	COG0601	transmembrane transport
A8C77_03570	COG4608	Belongs to the ABC transporter superfamily
A8C77_03580	COG2271	Major facilitator Superfamily
A8C77_03585	COG1846	Transcriptional regulator
A8C77_03590	COG0477	Major facilitator Superfamily
A8C77_03595	COG0477	Major facilitator Superfamily
A8C77_03600	COG1609	Transcriptional regulator
A8C77_03605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C77_03615	COG1129	ABC transporter
A8C77_03620	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C77_03625	COG1879	ABC-type sugar transport system periplasmic component
A8C77_03630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C77_03650	COG1063	alcohol dehydrogenase
A8C77_03665	COG3568	Endonuclease Exonuclease Phosphatase
A8C77_03690	COG1968	undecaprenyl-diphosphatase activity
A8C77_03695	COG0840	transmembrane signaling receptor activity
A8C77_03700	COG1388	LysM domain
A8C77_03700	COG3584	3D domain protein
A8C77_03705	COG1476	TRANSCRIPTIONal
A8C77_03720	COG3104	oligopeptide transport
A8C77_03725	COG1114	Component of the transport system for branched-chain amino acids
A8C77_03740	COG1113	amino acid transport
A8C77_03745	COG2252	PERMEase
A8C77_03770	COG0475	glutathione-regulated potassium exporter activity
A8C77_03770	COG0569	domain protein
A8C77_03785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8C77_03790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8C77_03795	COG0833	amino acid
A8C77_03800	COG4990	cell redox homeostasis
A8C77_03815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C77_03820	COG0697	spore germination
A8C77_03825	COG0531	amino acid
A8C77_03840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A8C77_03845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A8C77_03850	COG1918	ferrous iron import across plasma membrane
A8C77_03850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A8C77_03855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8C77_03860	COG0573	inorganic phosphate transmembrane transporter activity
A8C77_03865	COG0581	inorganic phosphate transmembrane transporter activity
A8C77_03875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C77_03990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A8C77_04015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A8C77_04020	COG1116	anion transmembrane transporter activity
A8C77_04025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C77_04030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C77_04035	COG0352	thiamine-phosphate diphosphorylase activity
A8C77_04040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C77_04045	COG2104	thiamine diphosphate biosynthetic process
A8C77_04055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C77_04060	COG0351	phosphomethylpyrimidine kinase
A8C77_04100	COG2205	protein histidine kinase activity
A8C77_04105	COG2814	Major facilitator Superfamily
A8C77_04110	COG1846	Transcriptional regulator
A8C77_04125	COG2252	PERMEase
A8C77_04130	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_04145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C77_04150	COG1621	beta-fructofuranosidase activity
A8C77_04155	COG1263	PTS System
A8C77_04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_04160	COG1609	Transcriptional regulator
A8C77_04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C77_04175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A8C77_04215	COG0778	Nitroreductase
A8C77_04220	COG2719	SpoVR family
A8C77_04245	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8C77_04250	COG1937	Protein conserved in bacteria
A8C77_04255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_04255	COG0425	Belongs to the sulfur carrier protein TusA family
A8C77_04260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_04265	COG0425	Belongs to the sulfur carrier protein TusA family
A8C77_04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_04280	COG2210	Belongs to the sulfur carrier protein TusA family
A8C77_04285	COG0730	response to heat
A8C77_04295	COG1316	TRANSCRIPTIONal
A8C77_04300	COG0604	alcohol dehydrogenase
A8C77_04305	COG1283	sodium-dependent phosphate transmembrane transporter activity
A8C77_04320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C77_04320	COG3711	transcriptional antiterminator
A8C77_04325	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C77_04330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C77_04350	COG3584	3D domain protein
A8C77_04350	COG1388	LysM domain
A8C77_04355	COG0577	efflux transmembrane transporter activity
A8C77_04360	COG1136	(ABC) transporter
A8C77_04370	COG5522	Integral membrane protein (intg_mem_TP0381)
A8C77_04385	COG1114	Component of the transport system for branched-chain amino acids
A8C77_04390	COG3546	catalase activity
A8C77_04425	COG0586	Pfam SNARE associated Golgi protein
A8C77_04460	COG0531	amino acid
A8C77_04465	COG0475	glutathione-regulated potassium exporter activity
A8C77_04475	COG1737	Transcriptional regulator
A8C77_04485	COG1263	PTS System
A8C77_04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_04495	COG2259	Doxx family
A8C77_04510	COG0697	spore germination
A8C77_04515	COG1522	sequence-specific DNA binding
A8C77_04525	COG2076	Multidrug Resistance protein
A8C77_04530	COG2076	Multidrug Resistance protein
A8C77_04535	COG1309	transcriptional regulator
A8C77_04540	COG2814	Major facilitator Superfamily
A8C77_04545	COG1733	regulation of RNA biosynthetic process
A8C77_04555	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C77_04560	COG4533	DNA binding
A8C77_04565	COG2211	Major facilitator Superfamily
A8C77_04575	COG0693	protein deglycase activity
A8C77_04590	COG0531	amino acid
A8C77_04595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A8C77_04605	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_04615	COG1132	(ABC) transporter
A8C77_04625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C77_04630	COG0765	amino acid transport
A8C77_04635	COG1126	abc transporter atp-binding protein
A8C77_04650	COG0189	ligase activity
A8C77_04680	COG0028	Belongs to the TPP enzyme family
A8C77_04685	COG3527	Alpha-acetolactate decarboxylase
A8C77_04700	COG0561	phosphatase activity
A8C77_04715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C77_04730	COG0659	secondary active sulfate transmembrane transporter activity
A8C77_04750	COG0653	protein targeting
A8C77_04755	COG2244	polysaccharide biosynthetic process
A8C77_04765	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C77_04770	COG4196	transglutaminase domain protein
A8C77_04785	COG1696	Membrane protein involved in D-alanine export
A8C77_04800	COG1024	Enoyl-CoA hydratase
A8C77_04820	COG1363	Peptidase, m42
A8C77_04840	COG3938	Belongs to the proline racemase family
A8C77_04880	COG0601	transmembrane transport
A8C77_04885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C77_04895	COG4608	Belongs to the ABC transporter superfamily
A8C77_04925	COG0477	Major facilitator Superfamily
A8C77_04930	COG3290	protein histidine kinase activity
A8C77_04935	COG4565	transcriptional regulatory protein
A8C77_04940	COG3181	Tripartite tricarboxylate transporter family receptor
A8C77_04970	COG4978	Transcriptional regulator
A8C77_04970	COG0789	Transcriptional regulator
A8C77_04985	COG0305	Participates in initiation and elongation during chromosome replication
A8C77_05025	COG0477	Major facilitator Superfamily
A8C77_05075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A8C77_05075	COG3320	Male sterility
A8C77_05100	COG1183	phosphatidylcholine synthase activity
A8C77_05120	COG2376	Dihydroxyacetone kinase
A8C77_05130	COG2376	Dihydroxyacetone kinase
A8C77_05135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A8C77_05140	COG1959	2 iron, 2 sulfur cluster binding
A8C77_05165	COG2770	Histidine kinase
A8C77_05165	COG3437	response regulator, receiver
A8C77_05215	COG3237	CsbD-like
A8C77_05240	COG1191	sigma factor activity
A8C77_05250	COG2208	phosphoserine phosphatase activity
A8C77_05255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A8C77_05260	COG0784	Response regulator, receiver
A8C77_05260	COG2205	protein histidine kinase activity
A8C77_05260	COG2198	Histidine kinase
A8C77_05260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C77_05285	COG0393	Putative heavy-metal-binding
A8C77_05320	COG0420	3'-5' exonuclease activity
A8C77_05325	COG4717	serine-type aminopeptidase activity
A8C77_05345	COG1309	transcriptional regulator
A8C77_05350	COG2814	Major facilitator Superfamily
A8C77_05355	COG0346	lactoylglutathione lyase activity
A8C77_05360	COG0346	lactoylglutathione lyase activity
A8C77_05365	COG0457	Tetratricopeptide repeat
A8C77_05370	COG2267	carboxylic ester hydrolase activity
A8C77_05390	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A8C77_05395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A8C77_05405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8C77_05445	COG0477	Major facilitator Superfamily
A8C77_05450	COG0477	Major facilitator Superfamily
A8C77_05460	COG3973	AAA domain
A8C77_05465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C77_05490	COG4980	gas vesicle protein
A8C77_05495	COG0537	adenosine 5'-monophosphoramidase activity
A8C77_05500	COG1131	(ABC) transporter
A8C77_05505	COG4473	ABC transporter
A8C77_05515	COG1309	transcriptional regulator
A8C77_05525	COG3402	PFAM membrane-flanked domain
A8C77_05535	COG3428	Bacterial PH domain
A8C77_05575	COG3402	PFAM membrane-flanked domain
A8C77_05580	COG3428	Bacterial PH domain
A8C77_05585	COG2329	Antibiotic biosynthesis monooxygenase
A8C77_05590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C77_05595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A8C77_05640	COG1309	transcriptional regulator
A8C77_05645	COG1511	domain protein
A8C77_05670	COG1609	Transcriptional regulator
A8C77_05680	COG1234	tRNA 3'-trailer cleavage
A8C77_05685	COG0095	Lipoate-protein ligase
A8C77_05695	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_05725	COG3209	COG3209 Rhs family protein
A8C77_05770	COG1408	metallophosphoesterase
A8C77_05775	COG1078	dGTPase activity
A8C77_05785	COG1595	DNA-templated transcription, initiation
A8C77_05790	COG3708	Transcriptional regulator
A8C77_05790	COG2207	Transcriptional regulator
A8C77_05805	COG2205	protein histidine kinase activity
A8C77_05810	COG0745	RESPONSE REGULATOR receiver
A8C77_05835	COG0501	Belongs to the peptidase M48B family
A8C77_05840	COG0840	transmembrane signaling receptor activity
A8C77_05845	COG0697	spore germination
A8C77_05860	COG0497	DNA recombination
A8C77_05865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A8C77_05870	COG2224	Isocitrate lyase
A8C77_05880	COG1278	Cold shock
A8C77_05895	COG4903	ComK protein
A8C77_05900	COG0398	Pfam SNARE associated Golgi protein
A8C77_05910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A8C77_05915	COG1074	ATP-dependent DNA helicase activity
A8C77_05960	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C77_05985	COG0367	asparagine synthase
A8C77_05995	COG0753	catalase activity
A8C77_06000	COG0004	ammonium transporteR
A8C77_06025	COG2996	Protein conserved in bacteria
A8C77_06035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C77_06045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_06060	COG0561	phosphatase activity
A8C77_06075	COG0542	response to heat
A8C77_06085	COG2267	carboxylic ester hydrolase activity
A8C77_06100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_06105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C77_06110	COG5504	Zn-dependent protease
A8C77_06120	COG0180	Tryptophanyl-tRNA synthetase
A8C77_06130	COG4166	transmembrane transport
A8C77_06135	COG0601	transmembrane transport
A8C77_06140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C77_06145	COG0444	Belongs to the ABC transporter superfamily
A8C77_06150	COG4608	Belongs to the ABC transporter superfamily
A8C77_06155	COG0534	Mate efflux family protein
A8C77_06160	COG4166	transmembrane transport
A8C77_06175	COG1393	Belongs to the ArsC family
A8C77_06180	COG0861	Integral membrane protein TerC family
A8C77_06185	COG4862	establishment of competence for transformation
A8C77_06190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C77_06200	COG1164	Oligoendopeptidase f
A8C77_06215	COG2346	COG2346, Truncated hemoglobins
A8C77_06220	COG4116	CYTH
A8C77_06230	COG2357	RelA SpoT domain protein
A8C77_06235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A8C77_06240	COG0564	pseudouridine synthase activity
A8C77_06255	COG0772	Belongs to the SEDS family
A8C77_06260	COG1216	Glycosyl transferase, family 2
A8C77_06280	COG0463	Glycosyl transferase, family 2
A8C77_06280	COG0457	Tetratricopeptide repeat
A8C77_06300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8C77_06315	COG1091	dTDP-4-dehydrorhamnose reductase activity
A8C77_06360	COG2153	protein acetylation
A8C77_06365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A8C77_06370	COG2382	esterase
A8C77_06385	COG5492	domain, Protein
A8C77_06390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C77_06405	COG0512	Glutamine amidotransferase of anthranilate synthase
A8C77_06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8C77_06440	COG1620	l-lactate permease
A8C77_06445	COG5634	Uncharacterized conserved protein (DUF2278)
A8C77_06495	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C77_06505	COG1476	TRANSCRIPTIONal
A8C77_06565	COG2226	methyltransferase
A8C77_06575	COG1686	Belongs to the peptidase S11 family
A8C77_06580	COG0681	Belongs to the peptidase S26 family
A8C77_06615	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_06620	COG3842	ATPase activity
A8C77_06625	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8C77_06630	COG1177	transmembrane transport
A8C77_06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8C77_06645	COG2409	Drug exporters of the RND superfamily
A8C77_06655	COG0564	pseudouridine synthase activity
A8C77_06665	COG2340	Cysteine-rich secretory protein family
A8C77_06670	COG0247	lactate metabolic process
A8C77_06675	COG0277	FAD linked oxidase domain protein
A8C77_06680	COG3835	regulator
A8C77_06690	COG0745	RESPONSE REGULATOR receiver
A8C77_06695	COG5002	protein histidine kinase activity
A8C77_06700	COG2186	Transcriptional regulator
A8C77_06720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A8C77_06730	COG2116	formate transmembrane transporter activity
A8C77_06735	COG0861	Integral membrane protein TerC family
A8C77_06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A8C77_06750	COG2030	dehydratase
A8C77_06770	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_06775	COG3243	poly(R)-hydroxyalkanoic acid synthase
A8C77_06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A8C77_06800	COG1840	ABC-type Fe3 transport system, periplasmic component
A8C77_06815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C77_06830	COG1349	DNA-binding transcription factor activity
A8C77_06855	COG2861	carbohydrate metabolic process
A8C77_06865	COG3852	Histidine kinase
A8C77_06870	COG1846	Transcriptional regulator
A8C77_06880	COG2318	DinB family
A8C77_06890	COG5002	protein histidine kinase activity
A8C77_06900	COG0720	synthase
A8C77_06915	COG4873	Protein conserved in bacteria
A8C77_06950	COG1780	Probably involved in ribonucleotide reductase function
A8C77_06970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8C77_06975	COG1725	Transcriptional regulator
A8C77_06980	COG1131	(ABC) transporter
A8C77_06990	COG1131	(ABC) transporter
A8C77_06995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A8C77_07010	COG1522	sequence-specific DNA binding
A8C77_07020	COG1335	isochorismatase
A8C77_07030	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8C77_07035	COG2070	2-Nitropropane dioxygenase
A8C77_07040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A8C77_07050	COG1696	Membrane protein involved in D-alanine export
A8C77_07075	COG0716	FMN binding
A8C77_07090	COG3173	Aminoglycoside phosphotransferase
A8C77_07110	COG0534	Mate efflux family protein
A8C77_07115	COG1968	undecaprenyl-diphosphatase activity
A8C77_07130	COG1846	Transcriptional regulator
A8C77_07140	COG1301	dicarboxylic acid transport
A8C77_07145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A8C77_07150	COG4709	membrane
A8C77_07155	COG3874	Sporulation protein YtfJ
A8C77_07185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C77_07190	COG0028	Belongs to the TPP enzyme family
A8C77_07195	COG0440	acetolactate synthase activity
A8C77_07200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A8C77_07210	COG0473	3-isopropylmalate dehydrogenase activity
A8C77_07235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A8C77_07270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A8C77_07285	COG1183	phosphatidylcholine synthase activity
A8C77_07290	COG1368	sulfuric ester hydrolase activity
A8C77_07300	COG0019	diaminopimelate decarboxylase activity
A8C77_07320	COG0529	Catalyzes the synthesis of activated sulfate
A8C77_07325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8C77_07345	COG1648	precorrin-2 dehydrogenase activity
A8C77_07355	COG0733	neurotransmitter:sodium symporter activity
A8C77_07375	COG1757	Na H antiporter
A8C77_07390	COG4758	membrane
A8C77_07395	COG4585	Histidine kinase
A8C77_07400	COG2197	response regulator
A8C77_07410	COG1114	Component of the transport system for branched-chain amino acids
A8C77_07420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A8C77_07445	COG1017	nitric oxide dioxygenase activity
A8C77_07445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C77_07465	COG0730	response to heat
A8C77_07470	COG0306	phosphate transporter
A8C77_07475	COG1392	Phosphate transport regulator
A8C77_07480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C77_07495	COG3852	Histidine kinase
A8C77_07500	COG1801	Protein of unknown function DUF72
A8C77_07510	COG0582	viral genome integration into host DNA
A8C77_07515	COG5002	protein histidine kinase activity
A8C77_07535	COG0392	lysyltransferase activity
A8C77_07535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A8C77_07550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8C77_07555	COG1686	Belongs to the peptidase S11 family
A8C77_07560	COG2715	membrane protein required for spore maturation
A8C77_07565	COG0700	Nucleoside recognition
A8C77_07570	COG1187	pseudouridine synthase activity
A8C77_07580	COG1333	cytochrome c biogenesis protein
A8C77_07585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C77_07590	COG0745	RESPONSE REGULATOR receiver
A8C77_07595	COG5002	protein histidine kinase activity
A8C77_07600	COG2096	Adenosyltransferase
A8C77_07615	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A8C77_07620	COG1141	Ferredoxin
A8C77_07625	COG4955	Helix-turn-helix domain
A8C77_07630	COG0514	ATP-dependent DNA helicase (RecQ)
A8C77_07635	COG1266	CAAX protease self-immunity
A8C77_07655	COG4862	establishment of competence for transformation
A8C77_07660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C77_07680	COG0492	ferredoxin-NADP+ reductase activity
A8C77_07685	COG0252	asparaginase activity
A8C77_07755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A8C77_07770	COG0142	geranyltranstransferase activity
A8C77_07780	COG0142	geranyltranstransferase activity
A8C77_07785	COG0105	UTP biosynthetic process
A8C77_07800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A8C77_07805	COG0457	Tetratricopeptide repeat
A8C77_07825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A8C77_07835	COG4347	Protein of unknown function (DUF1405)
A8C77_07850	COG2738	Putative neutral zinc metallopeptidase
A8C77_07860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_07870	COG1694	Mazg nucleotide pyrophosphohydrolase
A8C77_07885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A8C77_07890	COG0438	transferase activity, transferring glycosyl groups
A8C77_07930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C77_07930	COG1199	ATP-dependent helicase activity
A8C77_07950	COG3935	DnaD domain protein
A8C77_07955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8C77_07965	COG4499	WXG100 protein secretion system (Wss), protein YukC
A8C77_07965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C77_08005	COG4474	Belongs to the UPF0398 family
A8C77_08020	COG0116	Belongs to the methyltransferase superfamily
A8C77_08030	COG1199	ATP-dependent helicase activity
A8C77_08035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A8C77_08045	COG3173	Aminoglycoside phosphotransferase
A8C77_08050	COG0024	Methionine aminopeptidase
A8C77_08060	COG2233	PERMEase
A8C77_08065	COG2311	Membrane
A8C77_08070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A8C77_08080	COG0456	acetyltransferase
A8C77_08115	COG0754	glutathionylspermidine amidase activity
A8C77_08130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A8C77_08155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A8C77_08170	COG1215	transferase activity, transferring glycosyl groups
A8C77_08190	COG0454	-acetyltransferase
A8C77_08210	COG0328	RNA-DNA hybrid ribonuclease activity
A8C77_08250	COG1280	lysine exporter protein (LysE YggA)
A8C77_08265	COG3162	membrane
A8C77_08270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C77_08275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C77_08285	COG0475	glutathione-regulated potassium exporter activity
A8C77_08295	COG4978	Transcriptional regulator
A8C77_08295	COG0789	Transcriptional regulator
A8C77_08305	COG2323	membrane
A8C77_08310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8C77_08365	COG1923	regulation of RNA biosynthetic process
A8C77_08375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A8C77_08380	COG1360	Flagellar Motor Protein
A8C77_08385	COG2201	protein-glutamate methylesterase activity
A8C77_08395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8C77_08395	COG1776	CheC inhibitor of MCP methylation
A8C77_08410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A8C77_08430	COG1256	bacterial-type flagellum assembly
A8C77_08435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A8C77_08460	COG1815	bacterial-type flagellum-dependent cell motility
A8C77_08465	COG1558	bacterial-type flagellum-dependent cell motility
A8C77_08470	COG1677	Flagellar hook-basal body complex protein FliE
A8C77_08475	COG1766	The M ring may be actively involved in energy transduction
A8C77_08485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8C77_08495	COG1157	protein secretion by the type III secretion system
A8C77_08545	COG0463	Glycosyl transferase, family 2
A8C77_08575	COG0457	Tetratricopeptide repeat
A8C77_08575	COG0463	Glycosyl transferase, family 2
A8C77_08600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A8C77_08605	COG0741	lytic transglycosylase activity
A8C77_08620	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A8C77_08620	COG1776	CheC inhibitor of MCP methylation
A8C77_08630	COG1338	Plays a role in the flagellum-specific transport system
A8C77_08635	COG1987	bacterial-type flagellum assembly
A8C77_08645	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A8C77_08650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A8C77_08660	COG4786	Flagellar basal body rod
A8C77_08665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8C77_08690	COG1309	transcriptional regulator
A8C77_08710	COG2329	Antibiotic biosynthesis monooxygenase
A8C77_08740	COG3842	ATPase activity
A8C77_08745	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8C77_08750	COG1177	transmembrane transport
A8C77_08755	COG1234	tRNA 3'-trailer cleavage
A8C77_08780	COG1686	Belongs to the peptidase S11 family
A8C77_08790	COG0406	alpha-ribazole phosphatase activity
A8C77_08820	COG0367	asparagine synthase
A8C77_08850	COG1802	Transcriptional regulator
A8C77_08855	COG0697	spore germination
A8C77_08860	COG0523	cobalamin synthesis protein
A8C77_08865	COG0701	Predicted permease
A8C77_08875	COG0438	transferase activity, transferring glycosyl groups
A8C77_08875	COG1216	Glycosyl transferase, family 2
A8C77_08880	COG1757	Na H antiporter
A8C77_08885	COG0114	fumarate hydratase activity
A8C77_08915	COG3340	Belongs to the peptidase S51 family
A8C77_08935	COG0785	Cytochrome C biogenesis protein
A8C77_08970	COG2733	membrane
A8C77_09005	COG1131	(ABC) transporter
A8C77_09020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C77_09025	COG0528	UMP kinase activity
A8C77_09035	COG1027	Aspartate ammonia-lyase
A8C77_09040	COG0281	malic enzyme
A8C77_09045	COG4191	Histidine kinase
A8C77_09050	COG0784	Response regulator, receiver
A8C77_09055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A8C77_09115	COG1051	belongs to the nudix hydrolase family
A8C77_09120	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C77_09145	COG1966	Carbon starvation protein
A8C77_09160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_09170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8C77_09180	COG2223	nitrite transmembrane transporter activity
A8C77_09185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8C77_09200	COG2244	polysaccharide biosynthetic process
A8C77_09205	COG0733	neurotransmitter:sodium symporter activity
A8C77_09215	COG5566	PFAM Mor transcription activator
A8C77_09220	COG2323	membrane
A8C77_09235	COG2084	Dehydrogenase
A8C77_09250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A8C77_09260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C77_09265	COG0028	Belongs to the TPP enzyme family
A8C77_09270	COG0440	acetolactate synthase activity
A8C77_09275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A8C77_09285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8C77_09310	COG2814	Major facilitator Superfamily
A8C77_09315	COG3384	dioxygenase
A8C77_09325	COG3279	Response regulator of the LytR AlgR family
A8C77_09330	COG0427	acetyl-CoA hydrolase
A8C77_09350	COG1073	alpha beta
A8C77_09355	COG4166	transmembrane transport
A8C77_09385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_09405	COG1914	H( )-stimulated, divalent metal cation uptake system
A8C77_09420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8C77_09455	COG2390	Transcriptional regulator
A8C77_09465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_09470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A8C77_09485	COG4224	UPF0291 protein
A8C77_09505	COG0006	proline dipeptidase activity
A8C77_09510	COG2132	Multicopper oxidase
A8C77_09540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A8C77_09555	COG2372	response to copper ion
A8C77_09555	COG1276	copper resistance
A8C77_09560	COG4549	nuclear export factor GLE1
A8C77_09570	COG0697	spore germination
A8C77_09575	COG0583	DNA-binding transcription factor activity
A8C77_09580	COG1959	2 iron, 2 sulfur cluster binding
A8C77_09585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A8C77_09590	COG0778	Nitroreductase
A8C77_09605	COG0628	permease
A8C77_09610	COG0039	L-malate dehydrogenase activity
A8C77_09615	COG1231	oxidoreductase activity
A8C77_09620	COG0523	cobalamin synthesis protein
A8C77_09635	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_09640	COG2030	dehydratase
A8C77_09645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_09655	COG0411	ABC transporter
A8C77_09675	COG0583	DNA-binding transcription factor activity
A8C77_09685	COG1942	4-Oxalocrotonate Tautomerase
A8C77_09695	COG1846	Transcriptional regulator
A8C77_09705	COG1271	oxidase subunit
A8C77_09710	COG1294	oxidase, subunit
A8C77_09715	COG4988	ABC transporter
A8C77_09720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8C77_09740	COG1686	Belongs to the peptidase S11 family
A8C77_09755	COG1388	LysM domain
A8C77_09755	COG0791	NLP P60 protein
A8C77_09765	COG1132	(ABC) transporter
A8C77_09770	COG1132	(ABC) transporter
A8C77_09775	COG0745	RESPONSE REGULATOR receiver
A8C77_09780	COG5002	protein histidine kinase activity
A8C77_09790	COG0300	oxidoreductase activity
A8C77_09805	COG0726	polysaccharide deacetylase
A8C77_09825	COG0460	homoserine dehydrogenase
A8C77_09850	COG1316	TRANSCRIPTIONal
A8C77_09860	COG0745	RESPONSE REGULATOR receiver
A8C77_09865	COG5002	protein histidine kinase activity
A8C77_09870	COG0726	polysaccharide deacetylase
A8C77_09880	COG1285	pathogenesis
A8C77_09885	COG1247	-acetyltransferase
A8C77_09895	COG4264	IucA IucC family
A8C77_09900	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_09915	COG1082	Xylose isomerase domain protein TIM barrel
A8C77_09930	COG1279	arginine transmembrane transporter activity
A8C77_09940	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8C77_09980	COG2002	toxin-antitoxin pair type II binding
A8C77_09985	COG1404	Belongs to the peptidase S8 family
A8C77_09990	COG0640	Transcriptional regulator
A8C77_09995	COG0667	Aldo Keto reductase
A8C77_10000	COG2814	Major facilitator Superfamily
A8C77_10025	COG0840	transmembrane signaling receptor activity
A8C77_10045	COG3949	Membrane
A8C77_10050	COG0783	Belongs to the Dps family
A8C77_10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C77_10075	COG1231	oxidoreductase activity
A8C77_10085	COG4989	oxidoreductase activity
A8C77_10090	COG0523	cobalamin synthesis protein
A8C77_10095	COG0456	acetyltransferase
A8C77_10155	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8C77_10155	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8C77_10165	COG0702	epimerase
A8C77_10175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C77_10185	COG4166	transmembrane transport
A8C77_10200	COG0406	alpha-ribazole phosphatase activity
A8C77_10210	COG5337	Spore coat protein CotH
A8C77_10215	COG1051	belongs to the nudix hydrolase family
A8C77_10220	COG0586	Pfam SNARE associated Golgi protein
A8C77_10225	COG2244	polysaccharide biosynthetic process
A8C77_10235	COG0701	Predicted permease
A8C77_10240	COG3689	TIGRFAM TIGR03943 family protein
A8C77_10245	COG1607	acyl-coa hydrolase
A8C77_10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C77_10265	COG0702	epimerase
A8C77_10270	COG2839	Protein conserved in bacteria
A8C77_10275	COG1253	flavin adenine dinucleotide binding
A8C77_10290	COG1114	Component of the transport system for branched-chain amino acids
A8C77_10295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_10315	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C77_10325	COG1876	peptidase activity
A8C77_10335	COG0154	amidase activity
A8C77_10340	COG2211	Major facilitator Superfamily
A8C77_10360	COG0561	phosphatase activity
A8C77_10370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A8C77_10390	COG1819	glycosyl
A8C77_10395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_10400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_10425	COG0456	acetyltransferase
A8C77_10475	COG3874	Sporulation protein YtfJ
A8C77_10500	COG2226	methyltransferase
A8C77_10520	COG1082	Xylose isomerase domain protein TIM barrel
A8C77_10525	COG0346	lactoylglutathione lyase activity
A8C77_10535	COG0604	alcohol dehydrogenase
A8C77_10540	COG1595	DNA-templated transcription, initiation
A8C77_10565	COG0386	Belongs to the glutathione peroxidase family
A8C77_10570	COG1305	Transglutaminase-like
A8C77_10575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A8C77_10580	COG0714	Associated with various cellular activities
A8C77_10595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8C77_10600	COG1140	nitrate reductase beta subunit
A8C77_10605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8C77_10610	COG2181	nitrate reductase activity
A8C77_10630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C77_10635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A8C77_10640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C77_10645	COG0303	'Molybdopterin
A8C77_10650	COG0314	molybdopterin synthase activity
A8C77_10660	COG2223	nitrite transmembrane transporter activity
A8C77_10675	COG1648	precorrin-2 dehydrogenase activity
A8C77_10685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A8C77_10685	COG1587	Uroporphyrinogen-III synthase
A8C77_10690	COG2146	nitrite reductase [NAD(P)H] activity
A8C77_10695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8C77_10700	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A8C77_10735	COG2359	stage V sporulation protein S
A8C77_10750	COG5632	N-Acetylmuramoyl-L-alanine amidase
A8C77_10765	COG1418	mRNA catabolic process
A8C77_10770	COG0488	(ABC) transporter
A8C77_10785	COG0629	single-stranded DNA binding
A8C77_10800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C77_10805	COG1413	lyase activity
A8C77_10820	COG2136	Putative SAM-dependent methyltransferase
A8C77_10820	COG2521	methyltransferase
A8C77_10825	COG0018	arginyl-trna synthetase
A8C77_10850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A8C77_10865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8C77_10870	COG0017	Asparaginyl-tRNA synthetase
A8C77_10890	COG1674	ftsk spoiiie
A8C77_10990	COG1929	Belongs to the glycerate kinase type-1 family
A8C77_10995	COG0471	metal ion transport
A8C77_11000	COG0745	RESPONSE REGULATOR receiver
A8C77_11005	COG5002	protein histidine kinase activity
A8C77_11005	COG3850	Histidine kinase
A8C77_11020	COG0733	neurotransmitter:sodium symporter activity
A8C77_11045	COG2610	gluconate transmembrane transporter activity
A8C77_11050	COG1454	alcohol dehydrogenase
A8C77_11055	COG1794	racemase activity, acting on amino acids and derivatives
A8C77_11065	COG0456	acetyltransferase
A8C77_11080	COG1131	(ABC) transporter
A8C77_11085	COG4473	ABC transporter
A8C77_11095	COG0546	phosphoglycolate phosphatase activity
A8C77_11115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C77_11130	COG0768	penicillin binding
A8C77_11135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A8C77_11140	COG0204	Acyl-transferase
A8C77_11145	COG1272	protein, Hemolysin III
A8C77_11155	COG0805	protein transport
A8C77_11165	COG1307	EDD domain protein, DegV family
A8C77_11170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A8C77_11175	COG1999	signal sequence binding
A8C77_11180	COG0071	Belongs to the small heat shock protein (HSP20) family
A8C77_11185	COG0367	asparagine synthase
A8C77_11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_11210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C77_11245	COG0668	transmembrane transport
A8C77_11250	COG4585	Histidine kinase
A8C77_11250	COG2203	Gaf domain
A8C77_11255	COG2197	response regulator
A8C77_11265	COG1737	Transcriptional regulator
A8C77_11270	COG1064	alcohol dehydrogenase
A8C77_11300	COG1070	Carbohydrate kinase
A8C77_11335	COG1125	glycine betaine transport
A8C77_11335	COG0517	IMP dehydrogenase activity
A8C77_11340	COG1174	glycine betaine transport
A8C77_11375	COG1253	flavin adenine dinucleotide binding
A8C77_11380	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_11385	COG5506	Protein of unknown function (DUF1694)
A8C77_11400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C77_11405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A8C77_11410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8C77_11415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8C77_11420	COG0456	acetyltransferase
A8C77_11425	COG3829	transcription factor binding
A8C77_11430	COG1509	lysine 2,3-aminomutase activity
A8C77_11470	COG4326	sporulation control protein
A8C77_11475	COG0671	phosphoesterase, PA-phosphatase related
A8C77_11480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A8C77_11485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C77_11515	COG1715	Restriction endonuclease
A8C77_11515	COG1787	Restriction endonuclease
A8C77_11600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C77_11640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C77_11640	COG4499	WXG100 protein secretion system (Wss), protein YukC
A8C77_11650	COG2814	Major facilitator Superfamily
A8C77_11655	COG4841	protein insertion into membrane
A8C77_11660	COG0372	Belongs to the citrate synthase family
A8C77_11665	COG2079	MmgE PrpD family protein
A8C77_11670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A8C77_11675	COG1960	acyl-CoA dehydrogenase activity
A8C77_11680	COG2084	Dehydrogenase
A8C77_11685	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_11690	COG1280	lysine exporter protein (LysE YggA)
A8C77_11695	COG1024	Enoyl-CoA hydratase
A8C77_11710	COG0420	3'-5' exonuclease activity
A8C77_11715	COG0419	ATPase involved in DNA repair
A8C77_11745	COG2223	nitrite transmembrane transporter activity
A8C77_11750	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_11755	COG1169	isochorismate synthase
A8C77_11760	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8C77_11765	COG3433	isochorismatase activity
A8C77_11765	COG1535	isochorismatase
A8C77_11770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8C77_11775	COG3251	PFAM MbtH domain protein
A8C77_11780	COG2814	Major facilitator Superfamily
A8C77_11795	COG0776	regulation of translation
A8C77_11805	COG2318	DinB family
A8C77_11815	COG1115	amino acid carrier protein
A8C77_11830	COG2329	Antibiotic biosynthesis monooxygenase
A8C77_11835	COG1187	pseudouridine synthase activity
A8C77_11840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A8C77_11855	COG0596	Alpha beta hydrolase
A8C77_11860	COG2814	Major facilitator Superfamily
A8C77_11880	COG2226	methyltransferase
A8C77_11925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_11960	COG1247	-acetyltransferase
A8C77_12000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_12010	COG1278	Cold shock
A8C77_12025	COG0010	Belongs to the arginase family
A8C77_12030	COG0561	phosphatase activity
A8C77_12075	COG0583	DNA-binding transcription factor activity
A8C77_12080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C77_12095	COG0583	DNA-binding transcription factor activity
A8C77_12100	COG2258	MOSC domain
A8C77_12115	COG1132	(ABC) transporter
A8C77_12120	COG1132	(ABC) transporter
A8C77_12140	COG1396	sequence-specific DNA binding
A8C77_12170	COG1595	DNA-templated transcription, initiation
A8C77_12220	COG2971	BadF BadG BcrA BcrD
A8C77_12225	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A8C77_12230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A8C77_12250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_12280	COG1309	transcriptional regulator
A8C77_12295	COG0577	efflux transmembrane transporter activity
A8C77_12295	COG1136	(ABC) transporter
A8C77_12300	COG0500	methyltransferase
A8C77_12300	COG3615	Tellurite resistance protein tehB
A8C77_12310	COG2226	methyltransferase
A8C77_12315	COG3961	Belongs to the TPP enzyme family
A8C77_12320	COG1846	Transcriptional regulator
A8C77_12360	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8C77_12375	COG1595	DNA-templated transcription, initiation
A8C77_12385	COG0768	penicillin binding
A8C77_12395	COG2367	Beta-lactamase
A8C77_12400	COG0671	phosphoesterase, PA-phosphatase related
A8C77_12405	COG1609	Transcriptional regulator
A8C77_12410	COG2814	Major facilitator Superfamily
A8C77_12415	COG0673	inositol 2-dehydrogenase activity
A8C77_12425	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_12445	COG3718	enzyme involved in inositol metabolism
A8C77_12470	COG0457	Tetratricopeptide repeat
A8C77_12475	COG1476	TRANSCRIPTIONal
A8C77_12490	COG1876	peptidase activity
A8C77_12510	COG1309	transcriptional regulator
A8C77_12530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_12540	COG1252	NADH dehydrogenase
A8C77_12545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_12560	COG1131	(ABC) transporter
A8C77_12570	COG1309	transcriptional regulator
A8C77_12585	COG1960	acyl-CoA dehydrogenase activity
A8C77_12590	COG0439	Biotin carboxylase
A8C77_12595	COG0511	ligase activity, forming carbon-carbon bonds
A8C77_12600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A8C77_12605	COG1024	Enoyl-CoA hydratase
A8C77_12610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A8C77_12615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8C77_12625	COG1247	-acetyltransferase
A8C77_12630	COG0572	uridine kinase
A8C77_12640	COG2318	DinB family
A8C77_12645	COG1686	Belongs to the peptidase S11 family
A8C77_12670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8C77_12710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8C77_12710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8C77_12725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C77_12735	COG2814	Major facilitator Superfamily
A8C77_12755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8C77_12775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_12790	COG1063	alcohol dehydrogenase
A8C77_12805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8C77_12810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8C77_12825	COG3773	Cell wall hydrolase
A8C77_12835	COG0745	RESPONSE REGULATOR receiver
A8C77_12865	COG1136	(ABC) transporter
A8C77_12890	COG0460	homoserine dehydrogenase
A8C77_12895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_12905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A8C77_12980	COG2124	cytochrome p450
A8C77_13015	COG0561	phosphatase activity
A8C77_13025	COG5002	protein histidine kinase activity
A8C77_13035	COG1819	glycosyl
A8C77_13040	COG1794	racemase activity, acting on amino acids and derivatives
A8C77_13050	COG1122	ATPase activity
A8C77_13060	COG2205	protein histidine kinase activity
A8C77_13075	COG0604	alcohol dehydrogenase
A8C77_13090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C77_13125	COG0693	protein deglycase activity
A8C77_13155	COG2814	Major facilitator Superfamily
A8C77_13170	COG0584	glycerophosphoryl diester phosphodiesterase
A8C77_13190	COG0697	spore germination
A8C77_13225	COG2223	nitrite transmembrane transporter activity
A8C77_13240	COG2816	NAD+ diphosphatase activity
A8C77_13245	COG0592	DNA-directed DNA polymerase activity
A8C77_13250	COG1051	belongs to the nudix hydrolase family
A8C77_13285	COG3878	Protein conserved in bacteria
A8C77_13315	COG4667	esterase of the alpha-beta hydrolase superfamily
A8C77_13340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C77_13355	COG0322	excinuclease ABC activity
A8C77_13395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C77_13420	COG1011	Hydrolase
A8C77_13440	COG0076	glutamate decarboxylase activity
A8C77_13455	COG1523	belongs to the glycosyl hydrolase 13 family
A8C77_13460	COG3227	Zinc metalloprotease (Elastase)
A8C77_13480	COG0201	protein transport
A8C77_13490	COG0697	spore germination
A8C77_13495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_13525	COG4129	membrane
A8C77_13530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_13545	COG2959	enzyme of heme biosynthesis
A8C77_13550	COG3409	Peptidoglycan-binding domain 1 protein
A8C77_13550	COG3773	Cell wall hydrolase
A8C77_13565	COG3483	tryptophan 2,3-dioxygenase activity
A8C77_13570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A8C77_13575	COG3844	kynureninase activity
A8C77_13580	COG1309	transcriptional regulator
A8C77_13610	COG3284	Transcriptional regulator
A8C77_13630	COG1349	DNA-binding transcription factor activity
A8C77_13650	COG1959	2 iron, 2 sulfur cluster binding
A8C77_13665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C77_13670	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C77_13675	COG0022	dehydrogenase e1 component
A8C77_13680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A8C77_13690	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_13695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A8C77_13695	COG0456	acetyltransferase
A8C77_13730	COG4176	ABC-type proline glycine betaine transport system permease component
A8C77_13735	COG4175	Glycine betaine
A8C77_13735	COG0517	IMP dehydrogenase activity
A8C77_13745	COG0740	serine-type endopeptidase activity
A8C77_13760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A8C77_13765	COG2153	protein acetylation
A8C77_13770	COG3397	chitin binding
A8C77_13785	COG2205	protein histidine kinase activity
A8C77_13815	COG2333	competence protein COMEC
A8C77_13815	COG0658	competence protein
A8C77_13865	COG3973	AAA domain
A8C77_13880	COG2105	PFAM AIG2 family protein
A8C77_13885	COG0514	ATP-dependent DNA helicase (RecQ)
A8C77_13915	COG4637	Psort location Cytoplasmic, score
A8C77_13940	COG3397	chitin binding
A8C77_13950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C77_13955	COG1115	amino acid carrier protein
A8C77_13960	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_13965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8C77_13975	COG3938	Belongs to the proline racemase family
A8C77_13980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C77_14020	COG0586	Pfam SNARE associated Golgi protein
A8C77_14035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A8C77_14040	COG0519	Catalyzes the synthesis of GMP from XMP
A8C77_14045	COG4166	transmembrane transport
A8C77_14055	COG4948	Mandelate Racemase Muconate Lactonizing
A8C77_14095	COG2936	dipeptidyl-peptidase activity
A8C77_14100	COG5002	protein histidine kinase activity
A8C77_14105	COG0745	RESPONSE REGULATOR receiver
A8C77_14145	COG1307	EDD domain protein, DegV family
A8C77_14165	COG2814	Major facilitator Superfamily
A8C77_14175	COG1664	Polymer-forming cytoskeletal
A8C77_14180	COG0789	Transcriptional regulator
A8C77_14185	COG4533	DNA binding
A8C77_14190	COG2814	Major facilitator Superfamily
A8C77_14190	COG0477	Major facilitator Superfamily
A8C77_14210	COG2261	transglycosylase associated protein
A8C77_14225	COG2226	methyltransferase
A8C77_14260	COG0436	Aminotransferase
A8C77_14265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A8C77_14270	COG5146	pantothenate kinase activity
A8C77_14295	COG1131	(ABC) transporter
A8C77_14345	COG0628	permease
A8C77_14360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C77_14365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C77_14370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C77_14375	COG1116	anion transmembrane transporter activity
A8C77_14415	COG2746	aminoglycoside 3-N-acetyltransferase activity
A8C77_14440	COG0697	spore germination
A8C77_14445	COG2318	DinB family
A8C77_14465	COG4912	Dna alkylation repair
A8C77_14475	COG0726	polysaccharide deacetylase
A8C77_14485	COG0861	Integral membrane protein TerC family
A8C77_14490	COG1368	sulfuric ester hydrolase activity
A8C77_14495	COG0488	(ABC) transporter
A8C77_14505	COG2409	Drug exporters of the RND superfamily
A8C77_14505	COG1033	growth of symbiont in host cell
A8C77_14510	COG1033	growth of symbiont in host cell
A8C77_14510	COG2409	Drug exporters of the RND superfamily
A8C77_14515	COG2409	Drug exporters of the RND superfamily
A8C77_14515	COG1033	growth of symbiont in host cell
A8C77_14520	COG1309	transcriptional regulator
A8C77_14535	COG0287	Prephenate dehydrogenase
A8C77_14540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A8C77_14545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A8C77_14550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A8C77_14550	COG1605	Chorismate mutase
A8C77_14595	COG1595	DNA-templated transcription, initiation
A8C77_14620	COG1879	ABC-type sugar transport system periplasmic component
A8C77_14630	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C77_14640	COG2390	Transcriptional regulator
A8C77_14675	COG2329	Antibiotic biosynthesis monooxygenase
A8C77_14695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_14705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A8C77_14710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C77_14715	COG4187	Peptidase family M20/M25/M40
A8C77_14720	COG1414	Transcriptional regulator
A8C77_14725	COG0833	amino acid
A8C77_14730	COG1690	Belongs to the RtcB family
A8C77_14735	COG3239	Fatty acid desaturase
A8C77_14740	COG1785	Belongs to the alkaline phosphatase family
A8C77_14750	COG3655	Transcriptional regulator
A8C77_14765	COG4377	Putative membrane peptidase family (DUF2324)
A8C77_14775	COG3279	Response regulator of the LytR AlgR family
A8C77_14785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_14790	COG0346	lactoylglutathione lyase activity
A8C77_14810	COG0714	Associated with various cellular activities
A8C77_14835	COG0463	Glycosyl transferase, family 2
A8C77_14860	COG0463	Glycosyl transferase, family 2
A8C77_14870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C77_14875	COG0753	catalase activity
A8C77_14885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A8C77_14910	COG0714	Associated with various cellular activities
A8C77_14920	COG0778	Nitroreductase
A8C77_14925	COG1846	Transcriptional regulator
A8C77_14960	COG1725	Transcriptional regulator
A8C77_14970	COG0577	efflux transmembrane transporter activity
A8C77_14970	COG1136	(ABC) transporter
A8C77_14995	COG2207	Transcriptional regulator
A8C77_15000	COG0456	acetyltransferase
A8C77_15020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_15040	COG0642	Histidine kinase
A8C77_15045	COG0745	RESPONSE REGULATOR receiver
A8C77_15050	COG0596	Alpha beta hydrolase
A8C77_15080	COG0730	response to heat
A8C77_15090	COG0833	amino acid
A8C77_15100	COG4335	DNA alkylation repair
A8C77_15150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A8C77_15190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8C77_15195	COG1414	Transcriptional regulator
A8C77_15210	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C77_15215	COG0640	Transcriptional regulator
A8C77_15225	COG1960	acyl-CoA dehydrogenase activity
A8C77_15260	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A8C77_15275	COG3848	Pyruvate phosphate dikinase
A8C77_15275	COG0574	Belongs to the PEP-utilizing enzyme family
A8C77_15280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_15295	COG5577	PFAM Coat F domain
A8C77_15300	COG3403	YqcI/YcgG family
A8C77_15305	COG1280	lysine exporter protein (LysE YggA)
A8C77_15340	COG1063	alcohol dehydrogenase
A8C77_15355	COG1027	Aspartate ammonia-lyase
A8C77_15360	COG0252	asparaginase activity
A8C77_15365	COG1396	sequence-specific DNA binding
A8C77_15375	COG0322	excinuclease ABC activity
A8C77_15380	COG0531	amino acid
A8C77_15385	COG1114	Component of the transport system for branched-chain amino acids
A8C77_15390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C77_15400	COG0281	malic enzyme
A8C77_15425	COG0697	spore germination
A8C77_15430	COG0784	Response regulator, receiver
A8C77_15440	COG2066	Belongs to the glutaminase family
A8C77_15470	COG0737	Belongs to the 5'-nucleotidase family
A8C77_15475	COG0753	catalase activity
A8C77_15480	COG2267	carboxylic ester hydrolase activity
A8C77_15485	COG1335	isochorismatase
A8C77_15505	COG0583	DNA-binding transcription factor activity
A8C77_15550	COG0415	Belongs to the DNA photolyase family
A8C77_15555	COG0288	reversible hydration of carbon dioxide
A8C77_15565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8C77_15570	COG5609	conserved protein (DUF2294)
A8C77_15580	COG1575	Belongs to the MenA family. Type 1 subfamily
A8C77_15585	COG2267	carboxylic ester hydrolase activity
A8C77_15590	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8C77_15595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C77_15600	COG1121	(ABC) transporter
A8C77_15630	COG0798	PFAM Bile acid sodium symporter
A8C77_15635	COG0346	lactoylglutathione lyase activity
A8C77_15640	COG0640	Transcriptional regulator
A8C77_15655	COG0443	Heat shock 70 kDa protein
A8C77_15670	COG1522	sequence-specific DNA binding
A8C77_15685	COG0346	lactoylglutathione lyase activity
A8C77_15710	COG2169	Transcriptional regulator
A8C77_15755	COG2814	Major facilitator Superfamily
A8C77_15780	COG0745	RESPONSE REGULATOR receiver
A8C77_15785	COG5002	protein histidine kinase activity
A8C77_15785	COG3850	Histidine kinase
A8C77_15815	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A8C77_15840	COG1476	TRANSCRIPTIONal
A8C77_15855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_15860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C77_15870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_15875	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A8C77_15890	COG1136	(ABC) transporter
A8C77_15895	COG0577	efflux transmembrane transporter activity
A8C77_15915	COG5002	protein histidine kinase activity
A8C77_15915	COG3850	Histidine kinase
A8C77_15925	COG2364	Membrane
A8C77_15930	COG1846	Transcriptional regulator
A8C77_15940	COG2808	Putative FMN-binding domain
A8C77_15945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_15950	COG2271	Major facilitator Superfamily
A8C77_15955	COG1556	Lactate utilization protein
A8C77_15960	COG1139	Iron-sulfur cluster binding protein
A8C77_15970	COG0583	DNA-binding transcription factor activity
A8C77_15980	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8C77_16005	COG0738	Major facilitator superfamily
A8C77_16010	COG0673	inositol 2-dehydrogenase activity
A8C77_16015	COG0561	phosphatase activity
A8C77_16025	COG1609	Transcriptional regulator
A8C77_16030	COG0457	Tetratricopeptide repeat
A8C77_16050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8C77_16080	COG0534	Mate efflux family protein
A8C77_16095	COG2814	Major facilitator Superfamily
A8C77_16100	COG1309	transcriptional regulator
A8C77_16115	COG0814	amino acid
A8C77_16120	COG1760	l-serine dehydratase
A8C77_16125	COG1760	l-serine dehydratase
A8C77_16135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C77_16140	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8C77_16150	COG1335	isochorismatase
A8C77_16155	COG1522	sequence-specific DNA binding
A8C77_16160	COG0531	amino acid
A8C77_16175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C77_16195	COG1595	DNA-templated transcription, initiation
A8C77_16210	COG0662	Cupin 2, conserved barrel domain protein
A8C77_16220	COG2207	Transcriptional regulator
A8C77_16220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_16275	COG0477	Major facilitator Superfamily
A8C77_16285	COG1846	Transcriptional regulator
A8C77_16290	COG2814	Major facilitator Superfamily
A8C77_16300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A8C77_16305	COG1131	(ABC) transporter
A8C77_16325	COG2076	Multidrug Resistance protein
A8C77_16330	COG1309	transcriptional regulator
A8C77_16345	COG2031	fatty acid transporter
A8C77_16355	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C77_16385	COG1122	ATPase activity
A8C77_16390	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A8C77_16405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8C77_16410	COG1288	antiporter activity
A8C77_16415	COG2356	endonuclease I
A8C77_16430	COG3620	sequence-specific DNA binding
A8C77_16435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A8C77_16440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C77_16445	COG0124	histidyl-tRNA synthetase
A8C77_16460	COG1733	regulation of RNA biosynthetic process
A8C77_16465	COG0778	Nitroreductase
A8C77_16485	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_16495	COG1131	(ABC) transporter
A8C77_16520	COG1011	Hydrolase
A8C77_16555	COG0346	lactoylglutathione lyase activity
A8C77_16560	COG1940	carbohydrate kinase activity
A8C77_16565	COG0738	Major facilitator superfamily
A8C77_16570	COG0110	maltose O-acetyltransferase activity
A8C77_16585	COG1136	(ABC) transporter
A8C77_16590	COG0180	Tryptophanyl-tRNA synthetase
A8C77_16595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A8C77_16600	COG0628	permease
A8C77_16620	COG2226	methyltransferase
A8C77_16630	COG0477	Major facilitator Superfamily
A8C77_16660	COG1253	flavin adenine dinucleotide binding
A8C77_16665	COG0789	Transcriptional regulator
A8C77_16670	COG0697	spore germination
A8C77_16675	COG1357	PFAM Pentapeptide repeats (8 copies)
A8C77_16680	COG3813	Protein conserved in bacteria
A8C77_16685	COG2706	6-phosphogluconolactonase activity
A8C77_16690	COG1070	Carbohydrate kinase
A8C77_16700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C77_16705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A8C77_16715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8C77_16720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8C77_16725	COG0604	alcohol dehydrogenase
A8C77_16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C77_16750	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_16775	COG0656	L-ascorbic acid biosynthetic process
A8C77_16780	COG2814	Major facilitator Superfamily
A8C77_16795	COG0346	lactoylglutathione lyase activity
A8C77_16800	COG0814	amino acid
A8C77_16825	COG1393	Belongs to the ArsC family
A8C77_16835	COG1733	regulation of RNA biosynthetic process
A8C77_16840	COG2188	Transcriptional regulator
A8C77_16850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8C77_16855	COG1733	regulation of RNA biosynthetic process
A8C77_16860	COG1733	regulation of RNA biosynthetic process
A8C77_16875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_16895	COG0384	phenazine biosynthesis protein PhzF
A8C77_16905	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_16915	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_16925	COG1733	regulation of RNA biosynthetic process
A8C77_16960	COG1191	sigma factor activity
A8C77_16975	COG1309	transcriptional regulator
A8C77_16995	COG3152	Membrane
A8C77_17020	COG1151	hydroxylamine reductase activity
A8C77_17030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_17035	COG3757	hydrolase, family 25
A8C77_17035	COG3409	Peptidoglycan-binding domain 1 protein
A8C77_17070	COG2072	flavoprotein involved in K transport
A8C77_17110	COG1113	amino acid transport
A8C77_17115	COG2814	Major facilitator Superfamily
A8C77_17150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A8C77_17155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C77_17175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_17190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_17195	COG3739	integral membrane protein
A8C77_17200	COG0384	phenazine biosynthesis protein PhzF
A8C77_17230	COG0583	DNA-binding transcription factor activity
A8C77_17250	COG1193	negative regulation of DNA recombination
A8C77_17265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A8C77_17270	COG1164	Oligoendopeptidase f
A8C77_17275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C77_17305	COG0584	glycerophosphoryl diester phosphodiesterase
A8C77_17330	COG0640	Transcriptional regulator
A8C77_17335	COG0604	alcohol dehydrogenase
A8C77_17355	COG2808	Putative FMN-binding domain
A8C77_17360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A8C77_17370	COG0385	Bile acid
A8C77_17375	COG0277	FAD linked oxidase domain protein
A8C77_17410	COG1216	Glycosyl transferase, family 2
A8C77_17415	COG1024	Enoyl-CoA hydratase
A8C77_17425	COG1285	pathogenesis
A8C77_17435	COG2514	catechol 2,3-dioxygenase activity
A8C77_17440	COG2720	vancomycin resistance protein
A8C77_17470	COG1278	Cold shock
A8C77_17480	COG0716	FMN binding
A8C77_17510	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_17520	COG0165	Argininosuccinate lyase
A8C77_17535	COG4145	pantothenate transmembrane transporter activity
A8C77_17545	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_17550	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_17560	COG1657	PFAM Prenyltransferase squalene oxidase
A8C77_17565	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A8C77_17570	COG2962	Rard protein
A8C77_17575	COG3326	Membrane
A8C77_17590	COG0489	protein tyrosine kinase activity
A8C77_17600	COG0314	molybdopterin synthase activity
A8C77_17605	COG0303	'Molybdopterin
A8C77_17610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C77_17615	COG2116	formate transmembrane transporter activity
A8C77_17625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A8C77_17630	COG5609	conserved protein (DUF2294)
A8C77_17635	COG2427	Protein of unknown function (DUF1641)
A8C77_17640	COG3383	formate dehydrogenase (NAD+) activity
A8C77_17650	COG0697	spore germination
A8C77_17690	COG2226	methyltransferase
A8C77_17695	COG4166	transmembrane transport
A8C77_17700	COG4166	transmembrane transport
A8C77_17705	COG4166	transmembrane transport
A8C77_17715	COG1316	TRANSCRIPTIONal
A8C77_17725	COG1595	DNA-templated transcription, initiation
A8C77_17750	COG1131	(ABC) transporter
A8C77_17760	COG0673	inositol 2-dehydrogenase activity
A8C77_17765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A8C77_17770	COG0187	DNA topoisomerase II activity
A8C77_17780	COG1832	CoA-binding protein
A8C77_17785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C77_17790	COG0745	RESPONSE REGULATOR receiver
A8C77_17805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A8C77_17810	COG4841	protein insertion into membrane
A8C77_17815	COG0824	Thioesterase
A8C77_17845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C77_17855	COG2274	protein secretion by the type I secretion system
A8C77_17860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A8C77_17870	COG0726	polysaccharide deacetylase
A8C77_17890	COG2211	Major facilitator Superfamily
A8C77_17900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8C77_17915	COG0183	Belongs to the thiolase family
A8C77_17920	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_17925	COG1268	BioY protein
A8C77_17930	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_17975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_17985	COG5002	protein histidine kinase activity
A8C77_17990	COG0400	carboxylic ester hydrolase activity
A8C77_17995	COG0346	lactoylglutathione lyase activity
A8C77_18000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C77_18005	COG0069	glutamate synthase activity
A8C77_18010	COG1902	pentaerythritol trinitrate reductase activity
A8C77_18015	COG1329	Transcriptional regulator
A8C77_18020	COG0010	Belongs to the arginase family
A8C77_18045	COG2226	methyltransferase
A8C77_18100	COG4846	Membrane protein involved in cytochrome C biogenesis
A8C77_18105	COG0785	Cytochrome C biogenesis protein
A8C77_18115	COG0583	DNA-binding transcription factor activity
A8C77_18120	COG1380	Effector of murein hydrolase LrgA
A8C77_18125	COG1346	cytolysis
A8C77_18140	COG0730	response to heat
A8C77_18150	COG5632	N-Acetylmuramoyl-L-alanine amidase
A8C77_18150	COG3409	Peptidoglycan-binding domain 1 protein
A8C77_18165	COG1132	(ABC) transporter
A8C77_18170	COG1132	(ABC) transporter
A8C77_18205	COG3639	organic phosphonate transmembrane transporter activity
A8C77_18210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A8C77_18225	COG0737	Belongs to the 5'-nucleotidase family
A8C77_18235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8C77_18255	COG1695	Transcriptional regulator
A8C77_18290	COG1388	LysM domain
A8C77_18290	COG3409	Peptidoglycan-binding domain 1 protein
A8C77_18290	COG5632	N-Acetylmuramoyl-L-alanine amidase
A8C77_18295	COG4824	toxin secretion phage lysis holin
A8C77_18460	COG1595	DNA-templated transcription, initiation
A8C77_18505	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A8C77_18585	COG1396	sequence-specific DNA binding
A8C77_18610	COG0174	glutamine synthetase
A8C77_18615	COG0789	Transcriptional regulator
A8C77_18620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A8C77_18630	COG2860	membrane
A8C77_18635	COG0464	growth
A8C77_18665	COG1388	LysM domain
A8C77_18665	COG3584	3D domain protein
A8C77_18670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C77_18670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C77_18670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C77_18675	COG1105	Belongs to the carbohydrate kinase PfkB family
A8C77_18680	COG1349	DNA-binding transcription factor activity
A8C77_18690	COG2322	membrane
A8C77_18705	COG1113	amino acid transport
A8C77_18715	COG1408	metallophosphoesterase
A8C77_18720	COG2116	formate transmembrane transporter activity
A8C77_18730	COG2217	Heavy metal translocating P-type atpase
A8C77_18735	COG2608	mercury ion transmembrane transporter activity
A8C77_18740	COG1937	Protein conserved in bacteria
A8C77_18750	COG2819	hydrolase of the alpha beta superfamily
A8C77_18755	COG1120	ATPase activity
A8C77_18760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_18765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_18770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_18780	COG0708	Exodeoxyribonuclease III
A8C77_18785	COG2169	Transcriptional regulator
A8C77_18790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C77_18795	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8C77_18805	COG2364	Membrane
A8C77_18820	COG2267	carboxylic ester hydrolase activity
A8C77_18825	COG0346	lactoylglutathione lyase activity
A8C77_18830	COG5001	Diguanylate cyclase
A8C77_18830	COG3300	MHYT domain
A8C77_18850	COG1346	cytolysis
A8C77_18855	COG1380	Effector of murein hydrolase LrgA
A8C77_18860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C77_18865	COG0596	Alpha beta hydrolase
A8C77_18865	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C77_18870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A8C77_18885	COG1404	Belongs to the peptidase S8 family
A8C77_18890	COG3773	Cell wall hydrolase
A8C77_18895	COG0562	UDP-galactopyranose mutase
A8C77_18900	COG1368	sulfuric ester hydrolase activity
A8C77_18905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A8C77_18915	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A8C77_18960	COG4550	Control of competence regulator ComK, YlbF/YmcA
A8C77_18965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A8C77_18970	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8C77_18975	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8C77_18975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8C77_18985	COG2359	stage V sporulation protein S
A8C77_18990	COG1692	metallophosphoesterase
A8C77_19015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A8C77_19020	COG1426	Protein conserved in bacteria
A8C77_19035	COG0300	oxidoreductase activity
A8C77_19040	COG0612	Peptidase, M16
A8C77_19045	COG0612	Peptidase, M16
A8C77_19075	COG2188	Transcriptional regulator
A8C77_19080	COG1674	ftsk spoiiie
A8C77_19090	COG0740	serine-type endopeptidase activity
A8C77_19095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A8C77_19110	COG0527	aspartate kinase activity
A8C77_19115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C77_19120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8C77_19125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8C77_19130	COG1873	PFAM PRC-barrel domain
A8C77_19135	COG0612	Peptidase, M16
A8C77_19140	COG0726	polysaccharide deacetylase
A8C77_19155	COG0196	riboflavin kinase activity
A8C77_19160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A8C77_19170	COG1550	Protein conserved in bacteria
A8C77_19180	COG1358	cellular component organization or biogenesis
A8C77_19185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A8C77_19190	COG0195	Participates in both transcription termination and antitermination
A8C77_19210	COG0750	zinc metalloprotease
A8C77_19215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A8C77_19220	COG4589	Belongs to the CDS family
A8C77_19225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A8C77_19235	COG0528	UMP kinase activity
A8C77_19265	COG4974	Belongs to the 'phage' integrase family
A8C77_19275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8C77_19285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8C77_19325	COG1837	Belongs to the UPF0109 family
A8C77_19335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8C77_19345	COG0552	protein localization to endoplasmic reticulum
A8C77_19350	COG1196	nuclear chromosome segregation
A8C77_19365	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_19370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8C77_19385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8C77_19390	COG1461	Dihydroxyacetone kinase
A8C77_19395	COG1302	Protein conserved in bacteria
A8C77_19410	COG1564	THIamine pyrophosphokinase
A8C77_19415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8C77_19420	COG1162	GTPase activity
A8C77_19425	COG2815	serine threonine protein kinase
A8C77_19425	COG0515	serine threonine protein kinase
A8C77_19430	COG0631	protein serine/threonine phosphatase activity
A8C77_19440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A8C77_19440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A8C77_19450	COG0242	peptide deformylase activity
A8C77_19455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8C77_19460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8C77_19470	COG0194	GDP metabolic process
A8C77_19480	COG1561	YicC-like family, N-terminal region
A8C77_19485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A8C77_19495	COG0006	proline dipeptidase activity
A8C77_19510	COG3069	C4-dicarboxylate transmembrane transporter activity
A8C77_19550	COG0505	Belongs to the CarA family
A8C77_19575	COG0564	pseudouridine synthase activity
A8C77_19590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A8C77_19595	COG3599	regulation of cell shape
A8C77_19600	COG2302	S4 RNA-binding domain
A8C77_19605	COG0762	integral membrane protein
A8C77_19615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A8C77_19625	COG1873	PFAM PRC-barrel domain
A8C77_19630	COG1191	sigma factor activity
A8C77_19635	COG1191	sigma factor activity
A8C77_19645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A8C77_19650	COG0849	cell division
A8C77_19655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A8C77_19660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8C77_19665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A8C77_19670	COG0772	Belongs to the SEDS family
A8C77_19685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8C77_19690	COG0768	penicillin binding
A8C77_19700	COG4839	cell division protein FtsL
A8C77_19715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8C77_19735	COG1399	metal-binding, possibly nucleic acid-binding protein
A8C77_19785	COG4824	toxin secretion phage lysis holin
A8C77_19880	COG1802	Transcriptional regulator
A8C77_19880	COG4626	Terminase
A8C77_19905	COG0582	viral genome integration into host DNA
A8C77_19980	COG1191	sigma factor activity
A8C77_20005	COG1484	DNA-dependent DNA replication
A8C77_20035	COG1396	sequence-specific DNA binding
A8C77_20045	COG1396	sequence-specific DNA binding
A8C77_20060	COG0582	viral genome integration into host DNA
A8C77_20070	COG3480	Lon protease (S16) C-terminal proteolytic domain
A8C77_20075	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8C77_20080	COG3314	Sporulation integral membrane protein YlbJ
A8C77_20090	COG0742	ribosomal rna small subunit methyltransferase
A8C77_20105	COG3679	Belongs to the UPF0342 family
A8C77_20110	COG0406	alpha-ribazole phosphatase activity
A8C77_20125	COG2340	Cysteine-rich secretory protein family
A8C77_20140	COG3336	cytochrome c oxidase
A8C77_20175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A8C77_20180	COG0772	Belongs to the SEDS family
A8C77_20185	COG4838	Belongs to the UPF0358 family
A8C77_20190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A8C77_20195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A8C77_20205	COG4896	Protein conserved in bacteria
A8C77_20230	COG0483	inositol monophosphate 1-phosphatase activity
A8C77_20250	COG1982	Orn Lys Arg decarboxylase major
A8C77_20295	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C77_20300	COG0022	dehydrogenase e1 component
A8C77_20305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A8C77_20315	COG0242	peptide deformylase activity
A8C77_20320	COG0561	phosphatase activity
A8C77_20330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A8C77_20335	COG0569	domain protein
A8C77_20355	COG0583	DNA-binding transcription factor activity
A8C77_20360	COG0517	IMP dehydrogenase activity
A8C77_20370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A8C77_20380	COG4703	Protein of unknown function (DUF1797)
A8C77_20395	COG2200	EAL domain
A8C77_20400	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_20405	COG1408	metallophosphoesterase
A8C77_20415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A8C77_20455	COG2814	Major facilitator Superfamily
A8C77_20475	COG3209	COG3209 Rhs family protein
A8C77_20485	COG2205	protein histidine kinase activity
A8C77_20495	COG0436	Aminotransferase
A8C77_20500	COG1609	Transcriptional regulator
A8C77_20505	COG3833	ABC-type maltose transport systems, permease component
A8C77_20510	COG1175	transmembrane transport
A8C77_20515	COG2182	Extracellular solute-binding protein
A8C77_20525	COG0366	Alpha amylase catalytic
A8C77_20530	COG3842	ATPase activity
A8C77_20570	COG0183	Belongs to the thiolase family
A8C77_20610	COG1695	Transcriptional regulator
A8C77_20615	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_20635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8C77_20640	COG0436	Aminotransferase
A8C77_20660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A8C77_20680	COG3706	GGDEF domain
A8C77_20685	COG0778	Nitroreductase
A8C77_20710	COG2190	(PTS) system
A8C77_20710	COG1263	PTS System
A8C77_20710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C77_20715	COG3711	transcriptional antiterminator
A8C77_20735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8C77_20765	COG1547	Domain of unknown function (DUF309)
A8C77_20770	COG0456	acetyltransferase
A8C77_20780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A8C77_20785	COG4086	secreted protein
A8C77_20790	COG0561	phosphatase activity
A8C77_20795	COG0697	spore germination
A8C77_20810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_20835	COG0733	neurotransmitter:sodium symporter activity
A8C77_20855	COG1686	Belongs to the peptidase S11 family
A8C77_20860	COG1725	Transcriptional regulator
A8C77_20865	COG1131	(ABC) transporter
A8C77_20885	COG1846	Transcriptional regulator
A8C77_20900	COG0598	Magnesium transport protein CorA
A8C77_20925	COG4974	Belongs to the 'phage' integrase family
A8C77_20935	COG0735	belongs to the Fur family
A8C77_20940	COG1300	Membrane
A8C77_20960	COG0667	Aldo Keto reductase
A8C77_20965	COG0656	L-ascorbic acid biosynthetic process
A8C77_20970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A8C77_20970	COG0456	acetyltransferase
A8C77_20980	COG4085	toxin activity
A8C77_20980	COG1525	nuclease
A8C77_20980	COG0737	Belongs to the 5'-nucleotidase family
A8C77_20990	COG0596	Alpha beta hydrolase
A8C77_20995	COG2056	Na+-H+ antiporter family
A8C77_21000	COG1609	Transcriptional regulator
A8C77_21005	COG0456	acetyltransferase
A8C77_21010	COG1073	alpha beta
A8C77_21025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C77_21025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C77_21030	COG0307	riboflavin synthase, alpha
A8C77_21050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A8C77_21055	COG4106	trans-aconitate 2-methyltransferase activity
A8C77_21060	COG1073	alpha beta
A8C77_21060	COG2226	methyltransferase
A8C77_21065	COG0156	8-amino-7-oxononanoate synthase activity
A8C77_21075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C77_21090	COG0737	Belongs to the 5'-nucleotidase family
A8C77_21100	COG1522	sequence-specific DNA binding
A8C77_21120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C77_21130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A8C77_21145	COG0300	oxidoreductase activity
A8C77_21150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_21160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C77_21165	COG1760	l-serine dehydratase
A8C77_21170	COG1760	l-serine dehydratase
A8C77_21190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8C77_21200	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8C77_21205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_21220	COG1376	ErfK ybiS ycfS ynhG family protein
A8C77_21225	COG4129	membrane
A8C77_21230	COG1126	abc transporter atp-binding protein
A8C77_21235	COG0765	amino acid transport
A8C77_21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C77_21255	COG2816	NAD+ diphosphatase activity
A8C77_21260	COG0772	Belongs to the SEDS family
A8C77_21270	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C77_21275	COG0022	dehydrogenase e1 component
A8C77_21280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A8C77_21285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C77_21295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C77_21300	COG0280	phosphate acetyltransferase
A8C77_21310	COG3829	transcription factor binding
A8C77_21310	COG3290	protein histidine kinase activity
A8C77_21320	COG0584	glycerophosphoryl diester phosphodiesterase
A8C77_21325	COG3093	addiction module antidote protein HigA
A8C77_21335	COG0745	RESPONSE REGULATOR receiver
A8C77_21345	COG0750	zinc metalloprotease
A8C77_21350	COG0497	DNA recombination
A8C77_21360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A8C77_21370	COG0142	geranyltranstransferase activity
A8C77_21395	COG1302	Protein conserved in bacteria
A8C77_21400	COG0439	Biotin carboxylase
A8C77_21405	COG0511	ligase activity, forming carbon-carbon bonds
A8C77_21450	COG3854	ATPases associated with a variety of cellular activities
A8C77_21475	COG0006	proline dipeptidase activity
A8C77_21490	COG3872	metal-dependent enzyme
A8C77_21500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C77_21520	COG0095	Lipoate-protein ligase
A8C77_21525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_21530	COG1609	Transcriptional regulator
A8C77_21540	COG2076	Multidrug Resistance protein
A8C77_21545	COG2076	Multidrug Resistance protein
A8C77_21585	COG1131	(ABC) transporter
A8C77_21590	COG1725	Transcriptional regulator
A8C77_21620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A8C77_21675	COG4970	Tfp pilus assembly protein FimT
A8C77_21685	COG1459	type II secretion system
A8C77_21690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8C77_21740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A8C77_21745	COG0646	methionine synthase
A8C77_21745	COG1410	methionine synthase
A8C77_21750	COG0646	methionine synthase
A8C77_21750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A8C77_21755	COG0626	cystathionine gamma-synthase activity
A8C77_21760	COG0626	cystathionine gamma-synthase activity
A8C77_21785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_21795	COG1940	carbohydrate kinase activity
A8C77_21800	COG4483	Protein conserved in bacteria
A8C77_21805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8C77_21815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A8C77_21820	COG0704	Plays a role in the regulation of phosphate uptake
A8C77_21825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A8C77_21830	COG0581	inorganic phosphate transmembrane transporter activity
A8C77_21835	COG0573	inorganic phosphate transmembrane transporter activity
A8C77_21840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8C77_21850	COG0477	Major facilitator Superfamily
A8C77_21855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8C77_21880	COG0735	belongs to the Fur family
A8C77_21885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C77_21890	COG1121	(ABC) transporter
A8C77_21895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_21925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A8C77_21930	COG2384	SAM-dependent methyltransferase
A8C77_21935	COG2010	Cytochrome c
A8C77_21940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8C77_21945	COG0358	DNA primase activity
A8C77_21965	COG0517	IMP dehydrogenase activity
A8C77_21980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A8C77_21985	COG0295	cytidine deaminase activity
A8C77_21990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8C77_22000	COG1480	7TM receptor with intracellular HD hydrolase
A8C77_22005	COG1702	phosphate starvation-inducible protein PhoH
A8C77_22025	COG1610	YqeY-like protein
A8C77_22035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A8C77_22040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8C77_22060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A8C77_22070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C77_22075	COG1733	regulation of RNA biosynthetic process
A8C77_22100	COG1466	dna polymerase III delta subunit
A8C77_22110	COG2333	competence protein COMEC
A8C77_22110	COG0658	competence protein
A8C77_22115	COG2131	deaminase
A8C77_22120	COG1555	photosystem II stabilization
A8C77_22120	COG1596	polysaccharide export
A8C77_22125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C77_22130	COG2226	methyltransferase
A8C77_22135	COG0799	negative regulation of ribosome biogenesis
A8C77_22140	COG1713	HD superfamily hydrolase involved in NAD metabolism
A8C77_22150	COG1534	Rna-binding protein
A8C77_22160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A8C77_22165	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A8C77_22180	COG1191	sigma factor activity
A8C77_22190	COG1595	DNA-templated transcription, initiation
A8C77_22200	COG0778	Nitroreductase
A8C77_22205	COG2357	RelA SpoT domain protein
A8C77_22215	COG1785	Belongs to the alkaline phosphatase family
A8C77_22225	COG2267	carboxylic ester hydrolase activity
A8C77_22260	COG1404	Belongs to the peptidase S8 family
A8C77_22265	COG3186	Phenylalanine-4-hydroxylase
A8C77_22275	COG2514	catechol 2,3-dioxygenase activity
A8C77_22280	COG2514	catechol 2,3-dioxygenase activity
A8C77_22285	COG2259	Doxx family
A8C77_22325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_22335	COG1012	belongs to the aldehyde dehydrogenase family
A8C77_22335	COG1454	alcohol dehydrogenase
A8C77_22340	COG0626	cystathionine gamma-synthase activity
A8C77_22345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8C77_22370	COG0768	penicillin binding
A8C77_22400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8C77_22420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8C77_22430	COG0628	permease
A8C77_22450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8C77_22460	COG0482	sulfurtransferase activity
A8C77_22465	COG1104	cysteine desulfurase activity
A8C77_22470	COG1959	2 iron, 2 sulfur cluster binding
A8C77_22475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8C77_22485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A8C77_22495	COG0124	histidyl-tRNA synthetase
A8C77_22510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C77_22520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A8C77_22520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A8C77_22525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A8C77_22530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C77_22530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C77_22540	COG2244	polysaccharide biosynthetic process
A8C77_22545	COG2323	membrane
A8C77_22555	COG1862	Preprotein translocase
A8C77_22585	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A8C77_22595	COG0697	spore germination
A8C77_22600	COG0697	spore germination
A8C77_22605	COG0640	Transcriptional regulator
A8C77_22630	COG0157	Belongs to the NadC ModD family
A8C77_22635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A8C77_22640	COG1104	cysteine desulfurase activity
A8C77_22645	COG1827	regulation of RNA biosynthetic process
A8C77_22650	COG2258	MOSC domain
A8C77_22655	COG0077	Prephenate dehydratase
A8C77_22660	COG0577	efflux transmembrane transporter activity
A8C77_22665	COG0577	efflux transmembrane transporter activity
A8C77_22670	COG1136	(ABC) transporter
A8C77_22675	COG5002	protein histidine kinase activity
A8C77_22685	COG0745	RESPONSE REGULATOR receiver
A8C77_22690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A8C77_22695	COG3290	protein histidine kinase activity
A8C77_22705	COG2868	ribosomal protein
A8C77_22715	COG1530	ribonuclease E activity
A8C77_22720	COG1994	Peptidase M50
A8C77_22725	COG0739	heme binding
A8C77_22730	COG2894	cell division
A8C77_22745	COG1792	Involved in formation and maintenance of cell shape
A8C77_22750	COG1077	Cell shape determining protein MreB Mrl
A8C77_22770	COG0285	dihydrofolate synthase activity
A8C77_22775	COG0525	valine-tRNA ligase activity
A8C77_22785	COG1388	LysM domain
A8C77_22795	COG0113	porphobilinogen synthase activity
A8C77_22800	COG1587	Uroporphyrinogen-III synthase
A8C77_22810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C77_22820	COG1846	Transcriptional regulator
A8C77_22825	COG1764	response to oxidative stress
A8C77_22840	COG1067	ATP-dependent peptidase activity
A8C77_22840	COG0470	DNA polymerase III
A8C77_22895	COG0622	Phosphoesterase
A8C77_22900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A8C77_22910	COG5401	PFAM Sporulation and spore germination
A8C77_22930	COG1309	transcriptional regulator
A8C77_22945	COG2197	response regulator
A8C77_22950	COG2233	PERMEase
A8C77_22960	COG0402	S-adenosylhomocysteine deaminase activity
A8C77_22965	COG0402	S-adenosylhomocysteine deaminase activity
A8C77_22985	COG0444	Belongs to the ABC transporter superfamily
A8C77_22990	COG4608	Belongs to the ABC transporter superfamily
A8C77_22995	COG3275	phosphorelay sensor kinase activity
A8C77_23000	COG3279	Response regulator of the LytR AlgR family
A8C77_23015	COG1983	PspC domain protein
A8C77_23020	COG1396	sequence-specific DNA binding
A8C77_23025	COG0697	spore germination
A8C77_23035	COG1959	2 iron, 2 sulfur cluster binding
A8C77_23040	COG1668	transmembrane transport
A8C77_23045	COG4152	abc transporter atp-binding protein
A8C77_23050	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A8C77_23060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A8C77_23065	COG1876	peptidase activity
A8C77_23070	COG0824	Thioesterase
A8C77_23075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8C77_23080	COG1053	succinate dehydrogenase
A8C77_23085	COG2009	succinate dehydrogenase
A8C77_23090	COG1719	4-vinyl reductase, 4VR
A8C77_23100	COG3118	belongs to the thioredoxin family
A8C77_23105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A8C77_23110	COG2086	electron transfer activity
A8C77_23115	COG1024	Enoyl-CoA hydratase
A8C77_23120	COG1309	transcriptional regulator
A8C77_23125	COG0318	PFAM AMP-dependent synthetase and ligase
A8C77_23145	COG2318	DinB family
A8C77_23175	COG1131	(ABC) transporter
A8C77_23180	COG2205	protein histidine kinase activity
A8C77_23185	COG0745	RESPONSE REGULATOR receiver
A8C77_23195	COG4895	conserved protein (DUF2196)
A8C77_23200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A8C77_23215	COG4509	Sortase family
A8C77_23220	COG1120	ATPase activity
A8C77_23235	COG5386	Cell surface protein
A8C77_23245	COG5386	Cell surface protein
A8C77_23250	COG1114	Component of the transport system for branched-chain amino acids
A8C77_23255	COG1187	pseudouridine synthase activity
A8C77_23270	COG1796	DNA polymerase
A8C77_23270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A8C77_23275	COG1286	toxin biosynthetic process
A8C77_23305	COG0017	Asparaginyl-tRNA synthetase
A8C77_23310	COG0072	phenylalanine-tRNA ligase activity
A8C77_23310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_23320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C77_23330	COG1418	mRNA catabolic process
A8C77_23355	COG2814	Major facilitator Superfamily
A8C77_23360	COG1566	PFAM secretion protein HlyD family protein
A8C77_23365	COG1309	transcriptional regulator
A8C77_23370	COG1363	Peptidase, m42
A8C77_23390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A8C77_23395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A8C77_23405	COG1484	DNA-dependent DNA replication
A8C77_23410	COG3611	Membrane attachment protein
A8C77_23420	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A8C77_23425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8C77_23430	COG0237	dephospho-CoA kinase activity
A8C77_23435	COG1971	Probably functions as a manganese efflux pump
A8C77_23440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A8C77_23445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A8C77_23445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A8C77_23450	COG5002	protein histidine kinase activity
A8C77_23455	COG0745	RESPONSE REGULATOR receiver
A8C77_23475	COG0538	isocitrate dehydrogenase activity
A8C77_23480	COG0372	Belongs to the citrate synthase family
A8C77_23495	COG0628	permease
A8C77_23500	COG3030	protein affecting phage T7 exclusion by the F plasmid
A8C77_23525	COG1725	Transcriptional regulator
A8C77_23530	COG0281	malic enzyme
A8C77_23535	COG0587	DNA-directed DNA polymerase activity
A8C77_23550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A8C77_23570	COG4109	DRTGG domain
A8C77_23585	COG0006	proline dipeptidase activity
A8C77_23620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_23625	COG0662	Cupin 2, conserved barrel domain protein
A8C77_23635	COG1476	TRANSCRIPTIONal
A8C77_23650	COG1028	Short-chain dehydrogenase reductase Sdr
A8C77_23655	COG0589	response to stress
A8C77_23695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_23715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A8C77_23720	COG0827	DNA restriction-modification system
A8C77_23725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A8C77_23730	COG3874	Sporulation protein YtfJ
A8C77_23740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A8C77_23745	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A8C77_23755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8C77_23770	COG1104	cysteine desulfurase activity
A8C77_23780	COG0583	DNA-binding transcription factor activity
A8C77_23785	COG0697	spore germination
A8C77_23795	COG1956	GAF domain-containing protein
A8C77_23800	COG0626	cystathionine gamma-synthase activity
A8C77_23820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A8C77_23830	COG1595	DNA-templated transcription, initiation
A8C77_23840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8C77_23845	COG0454	-acetyltransferase
A8C77_23850	COG0517	IMP dehydrogenase activity
A8C77_23855	COG0123	including yeast histone deacetylase and acetoin utilization protein
A8C77_23865	COG0745	RESPONSE REGULATOR receiver
A8C77_23875	COG0666	response to abiotic stimulus
A8C77_23910	COG1609	Transcriptional regulator
A8C77_23920	COG4851	CamS sex pheromone cAM373 precursor
A8C77_23925	COG3118	belongs to the thioredoxin family
A8C77_23935	COG2309	aminopeptidase activity
A8C77_23955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_23970	COG1674	ftsk spoiiie
A8C77_23980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_23985	COG4848	Belongs to the UPF0354 family
A8C77_23990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C77_23995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A8C77_24000	COG1363	Peptidase, m42
A8C77_24010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_24025	COG0510	thiamine kinase activity
A8C77_24030	COG1523	belongs to the glycosyl hydrolase 13 family
A8C77_24045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8C77_24050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8C77_24055	COG1349	DNA-binding transcription factor activity
A8C77_24060	COG1187	pseudouridine synthase activity
A8C77_24065	COG2244	polysaccharide biosynthetic process
A8C77_24070	COG2081	HI0933 family
A8C77_24075	COG2814	Major facilitator Superfamily
A8C77_24085	COG3832	glyoxalase III activity
A8C77_24105	COG1329	Transcriptional regulator
A8C77_24115	COG4975	Glucose uptake
A8C77_24130	COG0314	molybdopterin synthase activity
A8C77_24135	COG1763	Mo-molybdopterin cofactor biosynthetic process
A8C77_24140	COG0303	'Molybdopterin
A8C77_24150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C77_24175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C77_24185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A8C77_24230	COG2814	Major facilitator Superfamily
A8C77_24235	COG0475	glutathione-regulated potassium exporter activity
A8C77_24240	COG0490	domain, Protein
A8C77_24245	COG0582	viral genome integration into host DNA
A8C77_24255	COG1136	(ABC) transporter
A8C77_24275	COG1242	4 iron, 4 sulfur cluster binding
A8C77_24280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A8C77_24285	COG1131	(ABC) transporter
A8C77_24295	COG1794	racemase activity, acting on amino acids and derivatives
A8C77_24315	COG2267	carboxylic ester hydrolase activity
A8C77_24320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C77_24325	COG0671	phosphoesterase, PA-phosphatase related
A8C77_24330	COG0438	transferase activity, transferring glycosyl groups
A8C77_24340	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8C77_24395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A8C77_24400	COG5002	protein histidine kinase activity
A8C77_24405	COG4191	Histidine kinase
A8C77_24410	COG2267	carboxylic ester hydrolase activity
A8C77_24430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C77_24435	COG1116	anion transmembrane transporter activity
A8C77_24440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C77_24465	COG0494	nUDIX hydrolase
A8C77_24495	COG0288	reversible hydration of carbon dioxide
A8C77_24500	COG1271	oxidase subunit
A8C77_24505	COG1294	oxidase, subunit
A8C77_24525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_24550	COG1842	Phage shock protein A
A8C77_24585	COG5002	protein histidine kinase activity
A8C77_24590	COG0745	RESPONSE REGULATOR receiver
A8C77_24620	COG1597	lipid kinase activity
A8C77_24655	COG0586	Pfam SNARE associated Golgi protein
A8C77_24665	COG0577	efflux transmembrane transporter activity
A8C77_24670	COG1136	(ABC) transporter
A8C77_24675	COG2207	Transcriptional regulator
A8C77_24675	COG3708	Transcriptional regulator
A8C77_24680	COG0745	RESPONSE REGULATOR receiver
A8C77_24685	COG2205	protein histidine kinase activity
A8C77_24690	COG0577	efflux transmembrane transporter activity
A8C77_24700	COG0577	efflux transmembrane transporter activity
A8C77_24705	COG1136	(ABC) transporter
A8C77_24745	COG3964	amidohydrolase
A8C77_24775	COG4948	Mandelate Racemase Muconate Lactonizing
A8C77_24785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A8C77_24790	COG0596	Alpha beta hydrolase
A8C77_24795	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A8C77_24800	COG1169	isochorismate synthase
A8C77_24805	COG1575	Belongs to the MenA family. Type 1 subfamily
A8C77_24810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8C77_24815	COG1278	Cold shock
A8C77_24835	COG0058	SHG alpha-glucan phosphorylase activity
A8C77_24840	COG0297	glycogen (starch) synthase activity
A8C77_24845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A8C77_24850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A8C77_24860	COG0039	L-malate dehydrogenase activity
A8C77_24955	COG0544	peptidyl-prolyl cis-trans isomerase activity
A8C77_24990	COG1285	pathogenesis
A8C77_24995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8C77_25005	COG0166	Belongs to the GPI family
A8C77_25015	COG2155	Conserved Protein
A8C77_25020	COG1098	S1 RNA binding domain
A8C77_25025	COG0436	Aminotransferase
A8C77_25030	COG1522	sequence-specific DNA binding
A8C77_25035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8C77_25040	COG2267	carboxylic ester hydrolase activity
A8C77_25050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8C77_25070	COG5018	Exonuclease
A8C77_25075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C77_25090	COG0423	glycine-tRNA ligase activity
A8C77_25095	COG2050	protein possibly involved in aromatic compounds catabolism
A8C77_25105	COG1268	BioY protein
A8C77_25115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8C77_25120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A8C77_25135	COG3584	3D domain protein
A8C77_25150	COG1252	NADH dehydrogenase
A8C77_25165	COG3708	Transcriptional regulator
A8C77_25180	COG1683	Conserved Protein
A8C77_25200	COG0316	Belongs to the HesB IscA family
A8C77_25215	COG1252	NADH dehydrogenase
A8C77_25230	COG0390	transport system, permease component
A8C77_25235	COG2824	Alkylphosphonate utilization operon protein PhnA
A8C77_25275	COG4837	Protein of unknown function (DUF1462)
A8C77_25280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A8C77_25290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8C77_25295	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8C77_25310	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C77_25315	COG0647	UMP catabolic process
A8C77_25325	COG2445	Protein of unknown function DUF86
A8C77_25330	COG1494	fructose-1,6-bisphosphatase
A8C77_25350	COG4470	Protein conserved in bacteria
A8C77_25360	COG0789	Transcriptional regulator
A8C77_25365	COG4377	Putative membrane peptidase family (DUF2324)
A8C77_25390	COG0739	heme binding
A8C77_25400	COG3377	Domain of unknown function (DUF1805)
A8C77_25405	COG0737	Belongs to the 5'-nucleotidase family
A8C77_25415	COG1695	Transcriptional regulator
A8C77_25430	COG0719	Fe-S assembly protein
A8C77_25435	COG0822	iron-sulfur transferase activity
A8C77_25440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8C77_25445	COG0719	Fe-S assembly protein
A8C77_25450	COG0396	ATPase activity
A8C77_25455	COG1464	Belongs to the NlpA lipoprotein family
A8C77_25460	COG1464	Belongs to the NlpA lipoprotein family
A8C77_25465	COG2011	ABC-type metal ion transport system permease component
A8C77_25470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8C77_25485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C77_25490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A8C77_25500	COG1393	Belongs to the ArsC family
A8C77_25550	COG0039	L-malate dehydrogenase activity
A8C77_25570	COG1309	transcriptional regulator
A8C77_25575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C77_25580	COG1960	acyl-CoA dehydrogenase activity
A8C77_25585	COG0183	Belongs to the thiolase family
A8C77_25590	COG1024	Enoyl-CoA hydratase
A8C77_25590	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C77_25600	COG1686	Belongs to the peptidase S11 family
A8C77_25615	COG0011	TIGRFAM Protein of
A8C77_25620	COG0840	transmembrane signaling receptor activity
A8C77_25640	COG2814	Major facilitator Superfamily
A8C77_25645	COG0531	amino acid
A8C77_25655	COG0706	membrane insertase activity
A8C77_25665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A8C77_25700	COG0586	Pfam SNARE associated Golgi protein
A8C77_25710	COG1376	ErfK ybiS ycfS ynhG family protein
A8C77_25715	COG0745	RESPONSE REGULATOR receiver
A8C77_25720	COG5002	protein histidine kinase activity
A8C77_25730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C77_25745	COG2151	metal-sulfur cluster biosynthetic enzyme
A8C77_25750	COG3227	Zinc metalloprotease (Elastase)
A8C77_25755	COG1741	Belongs to the pirin family
A8C77_25770	COG0475	glutathione-regulated potassium exporter activity
A8C77_25775	COG0490	domain, Protein
A8C77_25785	COG1115	amino acid carrier protein
A8C77_25790	COG0783	Belongs to the Dps family
A8C77_25805	COG1611	Belongs to the LOG family
A8C77_25820	COG2311	Membrane
A8C77_25830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_25835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_25840	COG1115	amino acid carrier protein
A8C77_25845	COG1115	amino acid carrier protein
A8C77_25850	COG2910	NAD(P)H-binding
A8C77_25865	COG0656	L-ascorbic acid biosynthetic process
A8C77_25870	COG2814	Major facilitator Superfamily
A8C77_25875	COG1733	regulation of RNA biosynthetic process
A8C77_25885	COG1252	NADH dehydrogenase
A8C77_25890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A8C77_25895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8C77_25905	COG3290	protein histidine kinase activity
A8C77_25905	COG0840	transmembrane signaling receptor activity
A8C77_25915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A8C77_25920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A8C77_25935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C77_25940	COG3223	Belongs to the PsiE family
A8C77_25990	COG0557	exoribonuclease II activity
A8C77_25995	COG1647	Serine aminopeptidase, S33
A8C77_26000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8C77_26005	COG1346	cytolysis
A8C77_26105	COG4695	Portal protein
A8C77_26130	COG4974	Belongs to the 'phage' integrase family
A8C77_26140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A8C77_26145	COG0149	triose-phosphate isomerase activity
A8C77_26155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8C77_26170	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A8C77_26195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A8C77_26210	COG2323	membrane
A8C77_26215	COG0740	serine-type endopeptidase activity
A8C77_26220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C77_26230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A8C77_26240	COG1051	belongs to the nudix hydrolase family
A8C77_26250	COG0492	ferredoxin-NADP+ reductase activity
A8C77_26255	COG0457	Tetratricopeptide repeat
A8C77_26260	COG0110	maltose O-acetyltransferase activity
A8C77_26280	COG1950	PFAM Membrane protein of
A8C77_26290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A8C77_26295	COG0556	nucleotide-excision repair
A8C77_26315	COG0789	Transcriptional regulator
A8C77_26340	COG2855	membrane
A8C77_26345	COG0583	DNA-binding transcription factor activity
A8C77_26355	COG0655	NAD(P)H dehydrogenase (quinone) activity
A8C77_26370	COG1132	(ABC) transporter
A8C77_26375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C77_26380	COG0793	Belongs to the peptidase S41A family
A8C77_26380	COG3409	Peptidoglycan-binding domain 1 protein
A8C77_26385	COG2177	Part of the ABC transporter FtsEX involved in
A8C77_26390	COG2884	Cell division ATP-binding protein ftsE
A8C77_26405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8C77_26410	COG0653	protein targeting
A8C77_26415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8C77_26420	COG1278	Cold shock
A8C77_26425	COG1040	competence protein
A8C77_26430	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A8C77_26435	COG1388	LysM domain
A8C77_26435	COG0791	NLP P60 protein
A8C77_26440	COG1733	regulation of RNA biosynthetic process
A8C77_26450	COG1307	EDD domain protein, DegV family
A8C77_26455	COG1739	Uncharacterized protein family UPF0029
A8C77_26460	COG1316	TRANSCRIPTIONal
A8C77_26465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8C77_26470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A8C77_26475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8C77_26485	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8C77_26485	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A8C77_26500	COG3394	polysaccharide catabolic process
A8C77_26505	COG1486	melibiose metabolic process
A8C77_26510	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C77_26515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C77_26525	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A8C77_26530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A8C77_26535	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C77_26545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C77_26550	COG1301	dicarboxylic acid transport
A8C77_26560	COG0346	lactoylglutathione lyase activity
A8C77_26565	COG1511	domain protein
A8C77_26570	COG0583	DNA-binding transcription factor activity
A8C77_26575	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A8C77_26595	COG1271	oxidase subunit
A8C77_26600	COG1294	oxidase, subunit
A8C77_26605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C77_26615	COG1620	l-lactate permease
A8C77_26625	COG2389	metal-binding protein
A8C77_26635	COG1368	sulfuric ester hydrolase activity
A8C77_26650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C77_26670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C77_26675	COG1388	LysM domain
A8C77_26675	COG3584	3D domain protein
A8C77_26700	COG4715	Zinc finger, swim domain protein
A8C77_26705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A8C77_26735	COG1191	sigma factor activity
A8C77_26745	COG0577	efflux transmembrane transporter activity
A8C77_26750	COG1136	(ABC) transporter
A8C77_26785	COG5002	protein histidine kinase activity
A8C77_26790	COG0745	RESPONSE REGULATOR receiver
A8C77_26795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A8C77_26810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8C77_26815	COG1134	teichoic acid transport
A8C77_26820	COG1682	transport, permease protein
A8C77_26825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A8C77_26870	COG1609	Transcriptional regulator
A8C77_26885	COG0739	heme binding
A8C77_26900	COG3279	Response regulator of the LytR AlgR family
A8C77_26905	COG4555	ABC transporter
A8C77_26910	COG2385	sporulation resulting in formation of a cellular spore
A8C77_26915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A8C77_26925	COG4836	Membrane
A8C77_26930	COG1007	ATP synthesis coupled electron transport
A8C77_26935	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C77_26940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8C77_26950	COG0839	Belongs to the complex I subunit 6 family
A8C77_26965	COG0649	NAD binding
A8C77_26970	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C77_26980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C77_26985	COG5001	Diguanylate cyclase
A8C77_26985	COG3300	MHYT domain
A8C77_27035	COG0356	it plays a direct role in the translocation of protons across the membrane
A8C77_27070	COG0698	ribose 5-phosphate isomerase
A8C77_27080	COG2190	(PTS) system
A8C77_27085	COG2259	Doxx family
A8C77_27090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C77_27105	COG0009	L-threonylcarbamoyladenylate synthase
A8C77_27120	COG2890	protein-(glutamine-N5) methyltransferase activity
A8C77_27125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A8C77_27140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A8C77_27145	COG1494	fructose-1,6-bisphosphatase
A8C77_27150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A8C77_27165	COG4821	SIS domain
A8C77_27175	COG3343	RNA polymerase activity
A8C77_27185	COG1960	acyl-CoA dehydrogenase activity
A8C77_27190	COG1960	acyl-CoA dehydrogenase activity
A8C77_27195	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C77_27200	COG0183	Belongs to the thiolase family
A8C77_27205	COG2181	nitrate reductase activity
A8C77_27205	COG0247	lactate metabolic process
A8C77_27210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C77_27220	COG3300	MHYT domain
A8C77_27220	COG5001	Diguanylate cyclase
A8C77_27235	COG2197	response regulator
A8C77_27240	COG4585	Histidine kinase
A8C77_27245	COG0842	Transport permease protein
A8C77_27250	COG1131	(ABC) transporter
A8C77_27255	COG0024	Methionine aminopeptidase
A8C77_27275	COG2234	aminopeptidase activity
A8C77_27295	COG1595	DNA-templated transcription, initiation
A8C77_27300	COG0018	arginyl-trna synthetase
A8C77_27305	COG4506	Protein conserved in bacteria
A8C77_27310	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8C77_27325	COG0010	Belongs to the arginase family
A8C77_27330	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A8C77_27335	COG2814	Major facilitator Superfamily
A8C77_27340	COG0789	Transcriptional regulator
A8C77_27345	COG0584	glycerophosphoryl diester phosphodiesterase
A8C77_27350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C77_27360	COG1994	Peptidase M50
A8C77_27370	COG1078	dGTPase activity
A8C77_27375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C77_27380	COG1120	ATPase activity
A8C77_27385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_27390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_27395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C77_27415	COG0095	Lipoate-protein ligase
A8C77_27420	COG0280	phosphate acetyltransferase
A8C77_27435	COG3773	Cell wall hydrolase
A8C77_27445	COG2363	Small membrane protein
A8C77_27460	COG2233	PERMEase
A8C77_27465	COG0561	phosphatase activity
A8C77_27470	COG2814	Major facilitator Superfamily
A8C77_27480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A8C77_27485	COG1131	(ABC) transporter
A8C77_27490	COG2755	lipolytic protein G-D-S-L family
A8C77_27495	COG1609	Transcriptional regulator
A8C77_27505	COG0460	homoserine dehydrogenase
A8C77_27525	COG1011	Hydrolase
A8C77_27530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C77_27540	COG2197	response regulator
A8C77_27550	COG0351	phosphomethylpyrimidine kinase
A8C77_27555	COG3706	GGDEF domain
A8C77_27560	COG2879	small protein
A8C77_27565	COG1966	Carbon starvation protein
A8C77_27570	COG3279	Response regulator of the LytR AlgR family
A8C77_27575	COG0477	Major facilitator Superfamily
A8C77_27600	COG0840	transmembrane signaling receptor activity
A8C77_27610	COG1607	acyl-coa hydrolase
A8C77_27625	COG0488	(ABC) transporter
A8C77_27650	COG0463	Glycosyl transferase, family 2
A8C77_27655	COG1309	transcriptional regulator
A8C77_27660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C77_27665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A8C77_27665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A8C77_27670	COG0628	permease
A8C77_27685	COG3279	Response regulator of the LytR AlgR family
A8C77_27690	COG3275	phosphorelay sensor kinase activity
A8C77_27695	COG2814	Major facilitator Superfamily
A8C77_27700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C77_27705	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A8C77_27710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8C77_27730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A8C77_27735	COG1272	protein, Hemolysin III
A8C77_27755	COG0516	GMP reductase activity
A8C77_27760	COG1164	Oligoendopeptidase f
A8C77_27780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C77_27785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A8C77_27790	COG4853	Protein conserved in bacteria
A8C77_27795	COG4863	YycH protein
A8C77_27800	COG5002	protein histidine kinase activity
A8C77_27805	COG0745	RESPONSE REGULATOR receiver
A8C77_27835	COG0305	Participates in initiation and elongation during chromosome replication
A8C77_27845	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A8C77_27850	COG4241	membrane
A8C77_27860	COG0629	single-stranded DNA binding
A8C77_27870	COG0012	GTP binding
A8C77_27875	COG4481	Protein conserved in bacteria
A8C77_27880	COG0668	transmembrane transport
A8C77_27890	COG1475	DNA binding
A8C77_27895	COG1192	Involved in chromosome partitioning
A8C77_27915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A8C77_27920	COG1847	R3H domain protein
A8C77_27925	COG0706	membrane insertase activity
A8C77_27980	COG3344	reverse transcriptase
A8C77_28060	COG3344	reverse transcriptase
A8C77_28265	COG4962	Type ii secretion system protein e
A8C77_28400	COG2311	Membrane
A8C77_28425	COG4196	transglutaminase domain protein
A8C77_28430	COG0671	phosphoesterase, PA-phosphatase related
A8C77_28455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8C77_28460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A8C77_28630	COG2002	toxin-antitoxin pair type II binding
A8C77_28640	COG4974	Belongs to the 'phage' integrase family
A8C77_28680	COG2801	Transposase and inactivated derivatives
A8C77_28700	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8C77_28710	COG4974	Belongs to the 'phage' integrase family
A8C77_28735	COG0457	Tetratricopeptide repeat
A8C77_28740	COG1923	regulation of RNA biosynthetic process
A8C77_28820	COG0741	lytic transglycosylase activity
A8C77_28820	COG0791	NLP P60 protein
A8C77_28965	COG1192	Involved in chromosome partitioning
A8C77_28985	COG2801	Transposase and inactivated derivatives
A8C77_29015	COG1683	Conserved Protein
A8C77_29020	COG1309	transcriptional regulator
A8C77_29090	COG0681	Belongs to the peptidase S26 family
A8C77_29120	COG1280	lysine exporter protein (LysE YggA)
A8C77_29155	COG4166	transmembrane transport
A8C77_29170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8C77_29230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8C77_29235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone