locus-tag	class	description
KM391_00010	COG0592	DNA-directed DNA polymerase activity
KM391_00015	COG2501	S4 domain
KM391_00025	COG0187	DNA topoisomerase II activity
KM391_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM391_00065	COG0516	GMP reductase activity
KM391_00065	COG0517	IMP dehydrogenase activity
KM391_00070	COG1686	Belongs to the peptidase S11 family
KM391_00100	COG1428	Deoxynucleoside kinase
KM391_00105	COG1428	Deoxynucleoside kinase
KM391_00110	COG1335	isochorismatase
KM391_00115	COG0590	tRNA wobble adenosine to inosine editing
KM391_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM391_00180	COG1982	Orn Lys Arg decarboxylase major
KM391_00190	COG0470	DNA polymerase III
KM391_00195	COG1774	PSP1 C-terminal conserved region
KM391_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM391_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM391_00220	COG2002	toxin-antitoxin pair type II binding
KM391_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_00230	COG0084	hydrolase, TatD family'
KM391_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM391_00250	COG4466	Protein conserved in bacteria
KM391_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM391_00270	COG0251	oxidation-reduction process
KM391_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM391_00305	COG2002	toxin-antitoxin pair type II binding
KM391_00310	COG2244	polysaccharide biosynthetic process
KM391_00315	COG3956	TIGRFAM MazG family protein
KM391_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM391_00340	COG1098	S1 RNA binding domain
KM391_00355	COG2208	phosphoserine phosphatase activity
KM391_00360	COG0037	tRNA processing
KM391_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM391_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM391_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM391_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM391_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM391_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM391_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM391_00420	COG1396	sequence-specific DNA binding
KM391_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM391_00455	COG3880	PFAM UvrB UvrC protein
KM391_00465	COG0542	response to heat
KM391_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM391_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM391_00500	COG1045	serine acetyltransferase
KM391_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM391_00520	COG3688	RNA-binding protein containing a PIN domain
KM391_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM391_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM391_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM391_00565	COG2813	Specifically methylates the guanine in position
KM391_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM391_00580	COG1358	cellular component organization or biogenesis
KM391_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM391_00710	COG0201	protein transport
KM391_00720	COG0024	Methionine aminopeptidase
KM391_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM391_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM391_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_00795	COG0489	protein tyrosine kinase activity
KM391_00805	COG2194	sulfuric ester hydrolase activity
KM391_00810	COG0726	polysaccharide deacetylase
KM391_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM391_00895	COG4856	YbbR-like protein
KM391_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM391_00915	COG0596	Alpha beta hydrolase
KM391_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM391_00940	COG4946	Tricorn protease homolog
KM391_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM391_00940	COG1506	peptidase
KM391_00975	COG2011	ABC-type metal ion transport system permease component
KM391_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_00985	COG1464	Belongs to the NlpA lipoprotein family
KM391_00990	COG0604	alcohol dehydrogenase
KM391_01000	COG0277	FAD linked oxidase domain protein
KM391_01005	COG2271	Major facilitator Superfamily
KM391_01015	COG2814	Major facilitator Superfamily
KM391_01030	COG0601	transmembrane transport
KM391_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_01040	COG0444	Belongs to the ABC transporter superfamily
KM391_01045	COG4608	Belongs to the ABC transporter superfamily
KM391_01050	COG4166	transmembrane transport
KM391_01060	COG2207	Transcriptional regulator
KM391_01075	COG4166	transmembrane transport
KM391_01080	COG4166	transmembrane transport
KM391_01085	COG0656	L-ascorbic acid biosynthetic process
KM391_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_01105	COG4149	molybdate abc transporter
KM391_01115	COG1910	domain protein
KM391_01125	COG0583	DNA-binding transcription factor activity
KM391_01130	COG0697	spore germination
KM391_01145	COG0204	Acyl-transferase
KM391_01155	COG1609	Transcriptional regulator
KM391_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_01175	COG0084	hydrolase, TatD family'
KM391_01180	COG5298	Protein conserved in bacteria
KM391_01205	COG0488	(ABC) transporter
KM391_01220	COG0747	negative chemotaxis
KM391_01225	COG0601	transmembrane transport
KM391_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_01235	COG0444	Belongs to the ABC transporter superfamily
KM391_01240	COG4608	Belongs to the ABC transporter superfamily
KM391_01260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM391_01265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM391_01275	COG2814	Major facilitator Superfamily
KM391_01285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM391_01295	COG4294	response to UV
KM391_01300	COG0457	Tetratricopeptide repeat
KM391_01300	COG0705	Rhomboid family
KM391_01310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM391_01315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM391_01320	COG0864	Transcriptional regulator
KM391_01325	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM391_01330	COG2183	response to ionizing radiation
KM391_01425	COG0802	atpase or kinase
KM391_01430	COG1214	PFAM Peptidase M22, glycoprotease
KM391_01435	COG0456	acetyltransferase
KM391_01445	COG0488	(ABC) transporter
KM391_01460	COG1266	CAAX protease self-immunity
KM391_01480	COG2252	PERMEase
KM391_01490	COG5002	protein histidine kinase activity
KM391_01520	COG2226	methyltransferase
KM391_01560	COG1968	undecaprenyl-diphosphatase activity
KM391_01575	COG2205	protein histidine kinase activity
KM391_01580	COG0745	RESPONSE REGULATOR receiver
KM391_01600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM391_01605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM391_01610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM391_01620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM391_01635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM391_01645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM391_01655	COG0151	Belongs to the GarS family
KM391_01680	COG0210	DNA helicase
KM391_01690	COG4851	CamS sex pheromone cAM373 precursor
KM391_01710	COG1335	isochorismatase
KM391_01715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_01720	COG2011	ABC-type metal ion transport system permease component
KM391_01725	COG1464	Belongs to the NlpA lipoprotein family
KM391_01745	COG1846	Transcriptional regulator
KM391_01770	COG1597	lipid kinase activity
KM391_01775	COG0546	phosphoglycolate phosphatase activity
KM391_01780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM391_01790	COG1012	belongs to the aldehyde dehydrogenase family
KM391_01795	COG2076	Multidrug Resistance protein
KM391_01800	COG2309	aminopeptidase activity
KM391_01815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_01820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM391_01825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM391_01835	COG4807	Protein conserved in bacteria
KM391_01860	COG1757	Na H antiporter
KM391_01865	COG1473	amidohydrolase
KM391_01880	COG0450	alkyl hydroperoxide reductase
KM391_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_01905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_01910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_01925	COG0166	Belongs to the GPI family
KM391_01960	COG5002	protein histidine kinase activity
KM391_01980	COG3541	Predicted nucleotidyltransferase
KM391_01985	COG2814	Major facilitator Superfamily
KM391_01990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_01990	COG0723	plastoquinol--plastocyanin reductase activity
KM391_02000	COG0765	amino acid transport
KM391_02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_02015	COG0840	transmembrane signaling receptor activity
KM391_02020	COG0840	transmembrane signaling receptor activity
KM391_02025	COG0366	Alpha amylase catalytic
KM391_02030	COG1263	PTS System
KM391_02030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_02030	COG2190	(PTS) system
KM391_02060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM391_02075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_02085	COG1116	anion transmembrane transporter activity
KM391_02090	COG0488	(ABC) transporter
KM391_02135	COG2270	Major facilitator Superfamily
KM391_02150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_02165	COG2310	stress, protein
KM391_02170	COG2310	stress, protein
KM391_02175	COG2310	stress, protein
KM391_02180	COG0861	Integral membrane protein TerC family
KM391_02190	COG3853	Toxic anion resistance protein (TelA)
KM391_02205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM391_02215	COG1295	ribonuclease BN
KM391_02220	COG2217	Heavy metal translocating P-type atpase
KM391_02225	COG0697	spore germination
KM391_02245	COG0586	Pfam SNARE associated Golgi protein
KM391_02260	COG3871	stress protein (general stress protein 26)
KM391_02265	COG0387	Pfam Sodium calcium exchanger
KM391_02275	COG0535	radical SAM domain protein
KM391_02300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM391_02305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM391_02310	COG0582	viral genome integration into host DNA
KM391_02320	COG1396	sequence-specific DNA binding
KM391_02335	COG1396	sequence-specific DNA binding
KM391_02370	COG1484	DNA-dependent DNA replication
KM391_02600	COG0101	tRNA pseudouridine synthase activity
KM391_02610	COG3829	transcription factor binding
KM391_02620	COG0833	amino acid
KM391_02625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM391_02655	COG1263	PTS System
KM391_02655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_02660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_02675	COG0463	Glycosyl transferase, family 2
KM391_02690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM391_02690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM391_02710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM391_02730	COG1228	amidohydrolase
KM391_02735	COG1090	epimerase
KM391_02765	COG1988	membrane-bound metal-dependent
KM391_02770	COG1194	a g-specific adenine glycosylase
KM391_02795	COG1132	(ABC) transporter
KM391_02800	COG4129	membrane
KM391_02805	COG0067	glutamate synthase
KM391_02805	COG0069	glutamate synthase activity
KM391_02805	COG0070	glutamate synthase
KM391_02815	COG4555	ABC transporter
KM391_02835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM391_02840	COG0735	belongs to the Fur family
KM391_02955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM391_02960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM391_02970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM391_02980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM391_02990	COG2766	serine protein kinase
KM391_03010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_03020	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM391_03025	COG2268	Band 7 protein
KM391_03035	COG3290	protein histidine kinase activity
KM391_03045	COG2851	Citrate transporter
KM391_03065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM391_03070	COG3842	ATPase activity
KM391_03075	COG1175	transmembrane transport
KM391_03080	COG0395	ABC-type sugar transport system, permease component
KM391_03090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM391_03095	COG0745	RESPONSE REGULATOR receiver
KM391_03100	COG5002	protein histidine kinase activity
KM391_03110	COG4990	cell redox homeostasis
KM391_03120	COG3290	protein histidine kinase activity
KM391_03125	COG4565	transcriptional regulatory protein
KM391_03130	COG3493	citrate carrier protein
KM391_03135	COG0281	malic enzyme
KM391_03150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_03160	COG5002	protein histidine kinase activity
KM391_03165	COG0745	RESPONSE REGULATOR receiver
KM391_03170	COG0454	-acetyltransferase
KM391_03170	COG0456	acetyltransferase
KM391_03175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM391_03180	COG3383	formate dehydrogenase (NAD+) activity
KM391_03185	COG2427	Protein of unknown function (DUF1641)
KM391_03200	COG0531	amino acid
KM391_03205	COG0640	Transcriptional regulator
KM391_03210	COG2217	Heavy metal translocating P-type atpase
KM391_03215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM391_03230	COG3227	Zinc metalloprotease (Elastase)
KM391_03250	COG2720	vancomycin resistance protein
KM391_03255	COG1316	TRANSCRIPTIONal
KM391_03260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_03265	COG0346	lactoylglutathione lyase activity
KM391_03270	COG1253	flavin adenine dinucleotide binding
KM391_03275	COG1027	Aspartate ammonia-lyase
KM391_03280	COG1620	l-lactate permease
KM391_03295	COG3104	oligopeptide transport
KM391_03300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_03320	COG2226	methyltransferase
KM391_03325	COG0156	8-amino-7-oxononanoate synthase activity
KM391_03340	COG4548	von Willebrand factor, type A
KM391_03345	COG0714	Associated with various cellular activities
KM391_03350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_03370	COG0531	amino acid
KM391_03375	COG2188	Transcriptional regulator
KM391_03380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_03380	COG1263	PTS System
KM391_03385	COG0366	Alpha amylase catalytic
KM391_03400	COG0697	spore germination
KM391_03410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_03415	COG1115	amino acid carrier protein
KM391_03420	COG1126	abc transporter atp-binding protein
KM391_03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_03430	COG0765	amino acid transport
KM391_03435	COG0765	amino acid transport
KM391_03440	COG0833	amino acid
KM391_03465	COG2378	regulation of single-species biofilm formation
KM391_03470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM391_03475	COG5002	protein histidine kinase activity
KM391_03490	COG0659	secondary active sulfate transmembrane transporter activity
KM391_03505	COG0747	negative chemotaxis
KM391_03515	COG0601	transmembrane transport
KM391_03520	COG4608	Belongs to the ABC transporter superfamily
KM391_03530	COG2271	Major facilitator Superfamily
KM391_03535	COG1846	Transcriptional regulator
KM391_03545	COG1609	Transcriptional regulator
KM391_03550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM391_03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM391_03570	COG1879	ABC-type sugar transport system periplasmic component
KM391_03595	COG1063	alcohol dehydrogenase
KM391_03610	COG3568	Endonuclease Exonuclease Phosphatase
KM391_03635	COG1968	undecaprenyl-diphosphatase activity
KM391_03640	COG0840	transmembrane signaling receptor activity
KM391_03645	COG1388	LysM domain
KM391_03645	COG3584	3D domain protein
KM391_03650	COG1476	TRANSCRIPTIONal
KM391_03665	COG3104	oligopeptide transport
KM391_03670	COG1114	Component of the transport system for branched-chain amino acids
KM391_03685	COG1113	amino acid transport
KM391_03690	COG2252	PERMEase
KM391_03715	COG0475	glutathione-regulated potassium exporter activity
KM391_03715	COG0569	domain protein
KM391_03730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM391_03735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM391_03740	COG0833	amino acid
KM391_03745	COG4990	cell redox homeostasis
KM391_03760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_03765	COG0697	spore germination
KM391_03770	COG0531	amino acid
KM391_03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_03790	COG1918	ferrous iron import across plasma membrane
KM391_03795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM391_03800	COG0573	inorganic phosphate transmembrane transporter activity
KM391_03805	COG0581	inorganic phosphate transmembrane transporter activity
KM391_03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM391_03930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM391_03950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM391_03955	COG1116	anion transmembrane transporter activity
KM391_03960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_03965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_03970	COG0352	thiamine-phosphate diphosphorylase activity
KM391_03975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_03980	COG2104	thiamine diphosphate biosynthetic process
KM391_03990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_03995	COG0351	phosphomethylpyrimidine kinase
KM391_04035	COG2205	protein histidine kinase activity
KM391_04040	COG2814	Major facilitator Superfamily
KM391_04045	COG1846	Transcriptional regulator
KM391_04060	COG2252	PERMEase
KM391_04065	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_04080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM391_04085	COG1621	beta-fructofuranosidase activity
KM391_04090	COG1263	PTS System
KM391_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_04095	COG1609	Transcriptional regulator
KM391_04105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_04110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM391_04145	COG0778	Nitroreductase
KM391_04150	COG2719	SpoVR family
KM391_04175	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM391_04180	COG1937	Protein conserved in bacteria
KM391_04185	COG0425	Belongs to the sulfur carrier protein TusA family
KM391_04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_04195	COG0425	Belongs to the sulfur carrier protein TusA family
KM391_04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_04210	COG2210	Belongs to the sulfur carrier protein TusA family
KM391_04215	COG0730	response to heat
KM391_04225	COG1316	TRANSCRIPTIONal
KM391_04230	COG0604	alcohol dehydrogenase
KM391_04235	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM391_04250	COG3711	transcriptional antiterminator
KM391_04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_04255	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_04260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_04280	COG1388	LysM domain
KM391_04280	COG3584	3D domain protein
KM391_04285	COG0577	efflux transmembrane transporter activity
KM391_04290	COG1136	(ABC) transporter
KM391_04300	COG5522	Integral membrane protein (intg_mem_TP0381)
KM391_04315	COG1114	Component of the transport system for branched-chain amino acids
KM391_04320	COG3546	catalase activity
KM391_04355	COG0586	Pfam SNARE associated Golgi protein
KM391_04390	COG0531	amino acid
KM391_04395	COG0475	glutathione-regulated potassium exporter activity
KM391_04405	COG1737	Transcriptional regulator
KM391_04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_04415	COG1263	PTS System
KM391_04425	COG2259	Doxx family
KM391_04440	COG0697	spore germination
KM391_04445	COG1522	sequence-specific DNA binding
KM391_04460	COG2076	Multidrug Resistance protein
KM391_04465	COG1309	transcriptional regulator
KM391_04470	COG2814	Major facilitator Superfamily
KM391_04475	COG1733	regulation of RNA biosynthetic process
KM391_04485	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_04490	COG4533	DNA binding
KM391_04495	COG2211	Major facilitator Superfamily
KM391_04505	COG0693	protein deglycase activity
KM391_04510	COG0753	catalase activity
KM391_04520	COG0531	amino acid
KM391_04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM391_04535	COG1012	belongs to the aldehyde dehydrogenase family
KM391_04540	COG1132	(ABC) transporter
KM391_04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_04555	COG0765	amino acid transport
KM391_04560	COG1126	abc transporter atp-binding protein
KM391_04575	COG0189	ligase activity
KM391_04605	COG0028	Belongs to the TPP enzyme family
KM391_04610	COG3527	Alpha-acetolactate decarboxylase
KM391_04625	COG0561	phosphatase activity
KM391_04640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM391_04655	COG0659	secondary active sulfate transmembrane transporter activity
KM391_04675	COG0653	protein targeting
KM391_04680	COG2244	polysaccharide biosynthetic process
KM391_04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_04695	COG4196	transglutaminase domain protein
KM391_04710	COG1696	Membrane protein involved in D-alanine export
KM391_04725	COG1024	Enoyl-CoA hydratase
KM391_04745	COG1363	Peptidase, m42
KM391_04765	COG3938	Belongs to the proline racemase family
KM391_04805	COG0601	transmembrane transport
KM391_04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_04820	COG4608	Belongs to the ABC transporter superfamily
KM391_04825	COG0322	excinuclease ABC activity
KM391_04855	COG0477	Major facilitator Superfamily
KM391_04860	COG3290	protein histidine kinase activity
KM391_04865	COG4565	transcriptional regulatory protein
KM391_04870	COG3181	Tripartite tricarboxylate transporter family receptor
KM391_04900	COG0789	Transcriptional regulator
KM391_04900	COG4978	Transcriptional regulator
KM391_04915	COG0305	Participates in initiation and elongation during chromosome replication
KM391_04955	COG0477	Major facilitator Superfamily
KM391_05000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_05000	COG3320	Male sterility
KM391_05005	COG1309	transcriptional regulator
KM391_05025	COG1183	phosphatidylcholine synthase activity
KM391_05045	COG2376	Dihydroxyacetone kinase
KM391_05055	COG2376	Dihydroxyacetone kinase
KM391_05060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_05065	COG1959	2 iron, 2 sulfur cluster binding
KM391_05095	COG2770	Histidine kinase
KM391_05095	COG3437	response regulator, receiver
KM391_05145	COG3237	CsbD-like
KM391_05170	COG1191	sigma factor activity
KM391_05180	COG2208	phosphoserine phosphatase activity
KM391_05185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM391_05190	COG2198	Histidine kinase
KM391_05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_05190	COG0784	Response regulator, receiver
KM391_05190	COG2205	protein histidine kinase activity
KM391_05245	COG0420	3'-5' exonuclease activity
KM391_05250	COG4717	serine-type aminopeptidase activity
KM391_05270	COG1309	transcriptional regulator
KM391_05275	COG2814	Major facilitator Superfamily
KM391_05280	COG0346	lactoylglutathione lyase activity
KM391_05285	COG0346	lactoylglutathione lyase activity
KM391_05290	COG0457	Tetratricopeptide repeat
KM391_05295	COG2267	carboxylic ester hydrolase activity
KM391_05315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM391_05320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM391_05330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM391_05370	COG0477	Major facilitator Superfamily
KM391_05375	COG0477	Major facilitator Superfamily
KM391_05385	COG3973	AAA domain
KM391_05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_05410	COG4980	gas vesicle protein
KM391_05415	COG0537	adenosine 5'-monophosphoramidase activity
KM391_05420	COG1131	(ABC) transporter
KM391_05425	COG4473	ABC transporter
KM391_05440	COG1309	transcriptional regulator
KM391_05450	COG3402	PFAM membrane-flanked domain
KM391_05500	COG3402	PFAM membrane-flanked domain
KM391_05505	COG3428	Bacterial PH domain
KM391_05510	COG2329	Antibiotic biosynthesis monooxygenase
KM391_05515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_05520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM391_05525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM391_05530	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM391_05565	COG1309	transcriptional regulator
KM391_05570	COG1511	domain protein
KM391_05605	COG1234	tRNA 3'-trailer cleavage
KM391_05610	COG0095	Lipoate-protein ligase
KM391_05620	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_05650	COG3209	COG3209 Rhs family protein
KM391_05690	COG1078	dGTPase activity
KM391_05700	COG1595	DNA-templated transcription, initiation
KM391_05705	COG2207	Transcriptional regulator
KM391_05705	COG3708	Transcriptional regulator
KM391_05720	COG2205	protein histidine kinase activity
KM391_05725	COG0745	RESPONSE REGULATOR receiver
KM391_05750	COG0501	Belongs to the peptidase M48B family
KM391_05755	COG0840	transmembrane signaling receptor activity
KM391_05760	COG0697	spore germination
KM391_05780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM391_05785	COG2224	Isocitrate lyase
KM391_05810	COG4903	ComK protein
KM391_05815	COG0398	Pfam SNARE associated Golgi protein
KM391_05825	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM391_05830	COG1074	ATP-dependent DNA helicase activity
KM391_05875	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM391_05900	COG0367	asparagine synthase
KM391_05905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM391_05910	COG0753	catalase activity
KM391_05915	COG0004	ammonium transporteR
KM391_05935	COG2996	Protein conserved in bacteria
KM391_05945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_05955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_05970	COG0561	phosphatase activity
KM391_05980	COG0542	response to heat
KM391_05990	COG2267	carboxylic ester hydrolase activity
KM391_06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM391_06015	COG5504	Zn-dependent protease
KM391_06025	COG0180	Tryptophanyl-tRNA synthetase
KM391_06035	COG4166	transmembrane transport
KM391_06040	COG0601	transmembrane transport
KM391_06045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_06050	COG0444	Belongs to the ABC transporter superfamily
KM391_06055	COG4608	Belongs to the ABC transporter superfamily
KM391_06060	COG0534	Mate efflux family protein
KM391_06065	COG4166	transmembrane transport
KM391_06080	COG0861	Integral membrane protein TerC family
KM391_06085	COG4862	establishment of competence for transformation
KM391_06090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_06100	COG1164	Oligoendopeptidase f
KM391_06110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM391_06115	COG2346	COG2346, Truncated hemoglobins
KM391_06120	COG4116	CYTH
KM391_06130	COG2357	RelA SpoT domain protein
KM391_06140	COG0564	pseudouridine synthase activity
KM391_06160	COG0463	Glycosyl transferase, family 2
KM391_06160	COG1216	Glycosyl transferase, family 2
KM391_06180	COG0463	Glycosyl transferase, family 2
KM391_06180	COG0457	Tetratricopeptide repeat
KM391_06200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM391_06215	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM391_06260	COG2153	protein acetylation
KM391_06270	COG2382	esterase
KM391_06285	COG5492	domain, Protein
KM391_06290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_06300	COG0512	Glutamine amidotransferase of anthranilate synthase
KM391_06300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM391_06335	COG1620	l-lactate permease
KM391_06340	COG5634	Uncharacterized conserved protein (DUF2278)
KM391_06395	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_06405	COG1476	TRANSCRIPTIONal
KM391_06465	COG2226	methyltransferase
KM391_06475	COG1686	Belongs to the peptidase S11 family
KM391_06480	COG0681	Belongs to the peptidase S26 family
KM391_06515	COG1012	belongs to the aldehyde dehydrogenase family
KM391_06520	COG3842	ATPase activity
KM391_06525	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM391_06530	COG1177	transmembrane transport
KM391_06535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM391_06545	COG2409	Drug exporters of the RND superfamily
KM391_06555	COG0564	pseudouridine synthase activity
KM391_06565	COG2340	Cysteine-rich secretory protein family
KM391_06570	COG0247	lactate metabolic process
KM391_06575	COG0277	FAD linked oxidase domain protein
KM391_06580	COG3835	regulator
KM391_06590	COG0745	RESPONSE REGULATOR receiver
KM391_06595	COG5002	protein histidine kinase activity
KM391_06600	COG2186	Transcriptional regulator
KM391_06620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM391_06635	COG2116	formate transmembrane transporter activity
KM391_06640	COG0861	Integral membrane protein TerC family
KM391_06645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_06655	COG2030	dehydratase
KM391_06675	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_06680	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM391_06685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_06690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_06705	COG1840	ABC-type Fe3 transport system, periplasmic component
KM391_06735	COG1349	DNA-binding transcription factor activity
KM391_06755	COG2861	carbohydrate metabolic process
KM391_06765	COG3852	Histidine kinase
KM391_06770	COG1846	Transcriptional regulator
KM391_06780	COG2318	DinB family
KM391_06785	COG5002	protein histidine kinase activity
KM391_06795	COG0720	synthase
KM391_06810	COG4873	Protein conserved in bacteria
KM391_06840	COG1780	Probably involved in ribonucleotide reductase function
KM391_06860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM391_06865	COG1725	Transcriptional regulator
KM391_06870	COG1131	(ABC) transporter
KM391_06880	COG1131	(ABC) transporter
KM391_06885	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_06900	COG1522	sequence-specific DNA binding
KM391_06910	COG1335	isochorismatase
KM391_06920	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_06925	COG2070	2-Nitropropane dioxygenase
KM391_06930	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM391_06940	COG1696	Membrane protein involved in D-alanine export
KM391_06965	COG0716	FMN binding
KM391_06980	COG3173	Aminoglycoside phosphotransferase
KM391_07000	COG0534	Mate efflux family protein
KM391_07005	COG1968	undecaprenyl-diphosphatase activity
KM391_07020	COG1846	Transcriptional regulator
KM391_07030	COG1301	dicarboxylic acid transport
KM391_07035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_07040	COG4709	membrane
KM391_07045	COG3874	Sporulation protein YtfJ
KM391_07070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_07075	COG0028	Belongs to the TPP enzyme family
KM391_07080	COG0440	acetolactate synthase activity
KM391_07085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM391_07095	COG0473	3-isopropylmalate dehydrogenase activity
KM391_07120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM391_07155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM391_07170	COG1183	phosphatidylcholine synthase activity
KM391_07175	COG1368	sulfuric ester hydrolase activity
KM391_07185	COG0019	diaminopimelate decarboxylase activity
KM391_07205	COG0529	Catalyzes the synthesis of activated sulfate
KM391_07210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM391_07230	COG1648	precorrin-2 dehydrogenase activity
KM391_07235	COG0733	neurotransmitter:sodium symporter activity
KM391_07255	COG1757	Na H antiporter
KM391_07270	COG4758	membrane
KM391_07275	COG4585	Histidine kinase
KM391_07280	COG2197	response regulator
KM391_07290	COG1114	Component of the transport system for branched-chain amino acids
KM391_07300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM391_07325	COG1017	nitric oxide dioxygenase activity
KM391_07325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM391_07340	COG0730	response to heat
KM391_07345	COG0306	phosphate transporter
KM391_07350	COG1392	Phosphate transport regulator
KM391_07355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_07375	COG1801	Protein of unknown function DUF72
KM391_07385	COG0582	viral genome integration into host DNA
KM391_07390	COG5002	protein histidine kinase activity
KM391_07410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM391_07410	COG0392	lysyltransferase activity
KM391_07425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_07430	COG1686	Belongs to the peptidase S11 family
KM391_07435	COG2715	membrane protein required for spore maturation
KM391_07440	COG0700	Nucleoside recognition
KM391_07445	COG1187	pseudouridine synthase activity
KM391_07455	COG1333	cytochrome c biogenesis protein
KM391_07460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM391_07465	COG0745	RESPONSE REGULATOR receiver
KM391_07470	COG5002	protein histidine kinase activity
KM391_07475	COG2096	Adenosyltransferase
KM391_07490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM391_07495	COG1141	Ferredoxin
KM391_07500	COG4955	Helix-turn-helix domain
KM391_07505	COG0514	ATP-dependent DNA helicase (RecQ)
KM391_07510	COG1266	CAAX protease self-immunity
KM391_07530	COG4862	establishment of competence for transformation
KM391_07535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM391_07555	COG0492	ferredoxin-NADP+ reductase activity
KM391_07630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_07645	COG0142	geranyltranstransferase activity
KM391_07655	COG0142	geranyltranstransferase activity
KM391_07675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM391_07680	COG0457	Tetratricopeptide repeat
KM391_07700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM391_07710	COG4347	Protein of unknown function (DUF1405)
KM391_07725	COG2738	Putative neutral zinc metallopeptidase
KM391_07735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_07740	COG1694	Mazg nucleotide pyrophosphohydrolase
KM391_07755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_07760	COG0438	transferase activity, transferring glycosyl groups
KM391_07795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM391_07795	COG1199	ATP-dependent helicase activity
KM391_07815	COG3935	DnaD domain protein
KM391_07820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM391_07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_07830	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM391_07890	COG0116	Belongs to the methyltransferase superfamily
KM391_07900	COG1199	ATP-dependent helicase activity
KM391_07905	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM391_07915	COG3173	Aminoglycoside phosphotransferase
KM391_07920	COG0024	Methionine aminopeptidase
KM391_07930	COG2233	PERMEase
KM391_07935	COG2311	Membrane
KM391_07940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_07950	COG0456	acetyltransferase
KM391_08000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_08025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM391_08040	COG1215	transferase activity, transferring glycosyl groups
KM391_08045	COG0438	transferase activity, transferring glycosyl groups
KM391_08060	COG0454	-acetyltransferase
KM391_08080	COG0328	RNA-DNA hybrid ribonuclease activity
KM391_08120	COG1280	lysine exporter protein (LysE YggA)
KM391_08135	COG3162	membrane
KM391_08140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_08145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_08155	COG0475	glutathione-regulated potassium exporter activity
KM391_08160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_08165	COG4978	Transcriptional regulator
KM391_08165	COG0789	Transcriptional regulator
KM391_08175	COG2323	membrane
KM391_08180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM391_08235	COG1923	regulation of RNA biosynthetic process
KM391_08245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM391_08250	COG1360	Flagellar Motor Protein
KM391_08255	COG2201	protein-glutamate methylesterase activity
KM391_08260	COG0643	Histidine kinase
KM391_08260	COG2198	Histidine kinase
KM391_08265	COG0643	Histidine kinase
KM391_08265	COG2198	Histidine kinase
KM391_08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_08270	COG1776	CheC inhibitor of MCP methylation
KM391_08285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM391_08305	COG1256	bacterial-type flagellum assembly
KM391_08330	COG1815	bacterial-type flagellum-dependent cell motility
KM391_08335	COG1558	bacterial-type flagellum-dependent cell motility
KM391_08350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_08360	COG1157	protein secretion by the type III secretion system
KM391_08410	COG0463	Glycosyl transferase, family 2
KM391_08445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM391_08450	COG0741	lytic transglycosylase activity
KM391_08465	COG1776	CheC inhibitor of MCP methylation
KM391_08465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_08475	COG1338	Plays a role in the flagellum-specific transport system
KM391_08480	COG1987	bacterial-type flagellum assembly
KM391_08490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM391_08495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM391_08505	COG4786	Flagellar basal body rod
KM391_08510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_08535	COG1309	transcriptional regulator
KM391_08555	COG2329	Antibiotic biosynthesis monooxygenase
KM391_08580	COG0583	DNA-binding transcription factor activity
KM391_08585	COG3842	ATPase activity
KM391_08590	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM391_08600	COG1234	tRNA 3'-trailer cleavage
KM391_08625	COG1686	Belongs to the peptidase S11 family
KM391_08635	COG0406	alpha-ribazole phosphatase activity
KM391_08665	COG0367	asparagine synthase
KM391_08695	COG1802	Transcriptional regulator
KM391_08700	COG0697	spore germination
KM391_08705	COG0523	cobalamin synthesis protein
KM391_08710	COG0701	Predicted permease
KM391_08720	COG1216	Glycosyl transferase, family 2
KM391_08720	COG0438	transferase activity, transferring glycosyl groups
KM391_08725	COG1757	Na H antiporter
KM391_08730	COG0114	fumarate hydratase activity
KM391_08755	COG3340	Belongs to the peptidase S51 family
KM391_08775	COG0785	Cytochrome C biogenesis protein
KM391_08805	COG2733	membrane
KM391_08840	COG1131	(ABC) transporter
KM391_08855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_08860	COG0528	UMP kinase activity
KM391_08870	COG1027	Aspartate ammonia-lyase
KM391_08875	COG0281	malic enzyme
KM391_08880	COG4191	Histidine kinase
KM391_08885	COG0784	Response regulator, receiver
KM391_08890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_08945	COG1051	belongs to the nudix hydrolase family
KM391_08950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_08960	COG2814	Major facilitator Superfamily
KM391_08975	COG1966	Carbon starvation protein
KM391_08990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM391_09010	COG2223	nitrite transmembrane transporter activity
KM391_09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_09030	COG2244	polysaccharide biosynthetic process
KM391_09035	COG0733	neurotransmitter:sodium symporter activity
KM391_09045	COG5566	PFAM Mor transcription activator
KM391_09050	COG2323	membrane
KM391_09065	COG2084	Dehydrogenase
KM391_09080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_09090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_09095	COG0028	Belongs to the TPP enzyme family
KM391_09100	COG0440	acetolactate synthase activity
KM391_09105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM391_09115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM391_09140	COG2814	Major facilitator Superfamily
KM391_09145	COG3384	dioxygenase
KM391_09155	COG3279	Response regulator of the LytR AlgR family
KM391_09160	COG0427	acetyl-CoA hydrolase
KM391_09180	COG1073	alpha beta
KM391_09210	COG0535	radical SAM domain protein
KM391_09215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_09235	COG1914	H( )-stimulated, divalent metal cation uptake system
KM391_09250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM391_09280	COG2390	Transcriptional regulator
KM391_09290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_09295	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM391_09310	COG4224	UPF0291 protein
KM391_09330	COG0006	proline dipeptidase activity
KM391_09335	COG2132	Multicopper oxidase
KM391_09350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM391_09365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_09380	COG1276	copper resistance
KM391_09380	COG2372	response to copper ion
KM391_09385	COG4549	nuclear export factor GLE1
KM391_09395	COG0697	spore germination
KM391_09400	COG0583	DNA-binding transcription factor activity
KM391_09405	COG1959	2 iron, 2 sulfur cluster binding
KM391_09410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM391_09415	COG0778	Nitroreductase
KM391_09425	COG0628	permease
KM391_09435	COG1231	oxidoreductase activity
KM391_09440	COG0523	cobalamin synthesis protein
KM391_09455	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_09460	COG2030	dehydratase
KM391_09465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_09475	COG0411	ABC transporter
KM391_09495	COG0583	DNA-binding transcription factor activity
KM391_09505	COG1942	4-Oxalocrotonate Tautomerase
KM391_09515	COG1846	Transcriptional regulator
KM391_09525	COG1271	oxidase subunit
KM391_09530	COG1294	oxidase, subunit
KM391_09535	COG4988	ABC transporter
KM391_09540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM391_09560	COG1686	Belongs to the peptidase S11 family
KM391_09575	COG0791	NLP P60 protein
KM391_09575	COG1388	LysM domain
KM391_09590	COG0745	RESPONSE REGULATOR receiver
KM391_09595	COG5002	protein histidine kinase activity
KM391_09605	COG0300	oxidoreductase activity
KM391_09640	COG0460	homoserine dehydrogenase
KM391_09665	COG1316	TRANSCRIPTIONal
KM391_09675	COG0745	RESPONSE REGULATOR receiver
KM391_09680	COG5002	protein histidine kinase activity
KM391_09695	COG1285	pathogenesis
KM391_09700	COG1247	-acetyltransferase
KM391_09720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_09730	COG1082	Xylose isomerase domain protein TIM barrel
KM391_09745	COG1279	arginine transmembrane transporter activity
KM391_09755	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM391_09795	COG2002	toxin-antitoxin pair type II binding
KM391_09800	COG1404	Belongs to the peptidase S8 family
KM391_09805	COG0640	Transcriptional regulator
KM391_09810	COG0667	Aldo Keto reductase
KM391_09815	COG2814	Major facilitator Superfamily
KM391_09840	COG0840	transmembrane signaling receptor activity
KM391_09855	COG3949	Membrane
KM391_09860	COG0783	Belongs to the Dps family
KM391_09875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_09885	COG1231	oxidoreductase activity
KM391_09895	COG4989	oxidoreductase activity
KM391_09900	COG0523	cobalamin synthesis protein
KM391_09905	COG0456	acetyltransferase
KM391_09960	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM391_09960	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM391_09970	COG0702	epimerase
KM391_09980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM391_09990	COG4166	transmembrane transport
KM391_10005	COG0406	alpha-ribazole phosphatase activity
KM391_10015	COG5337	Spore coat protein CotH
KM391_10020	COG1051	belongs to the nudix hydrolase family
KM391_10025	COG0586	Pfam SNARE associated Golgi protein
KM391_10030	COG2244	polysaccharide biosynthetic process
KM391_10040	COG0701	Predicted permease
KM391_10045	COG3689	TIGRFAM TIGR03943 family protein
KM391_10050	COG1607	acyl-coa hydrolase
KM391_10060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_10075	COG0702	epimerase
KM391_10080	COG2839	Protein conserved in bacteria
KM391_10085	COG1253	flavin adenine dinucleotide binding
KM391_10100	COG1114	Component of the transport system for branched-chain amino acids
KM391_10105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_10135	COG1876	peptidase activity
KM391_10145	COG0154	amidase activity
KM391_10150	COG2211	Major facilitator Superfamily
KM391_10170	COG0561	phosphatase activity
KM391_10180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM391_10185	COG4106	trans-aconitate 2-methyltransferase activity
KM391_10200	COG1819	glycosyl
KM391_10205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_10210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_10235	COG0456	acetyltransferase
KM391_10285	COG3874	Sporulation protein YtfJ
KM391_10310	COG2226	methyltransferase
KM391_10335	COG0346	lactoylglutathione lyase activity
KM391_10345	COG0604	alcohol dehydrogenase
KM391_10350	COG1595	DNA-templated transcription, initiation
KM391_10375	COG0386	Belongs to the glutathione peroxidase family
KM391_10380	COG1305	Transglutaminase-like
KM391_10385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM391_10390	COG0714	Associated with various cellular activities
KM391_10405	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM391_10410	COG1140	nitrate reductase beta subunit
KM391_10415	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM391_10420	COG2181	nitrate reductase activity
KM391_10440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM391_10445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM391_10450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_10455	COG0303	'Molybdopterin
KM391_10460	COG0314	molybdopterin synthase activity
KM391_10470	COG2223	nitrite transmembrane transporter activity
KM391_10485	COG1648	precorrin-2 dehydrogenase activity
KM391_10495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM391_10495	COG1587	Uroporphyrinogen-III synthase
KM391_10500	COG2146	nitrite reductase [NAD(P)H] activity
KM391_10505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM391_10510	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM391_10545	COG2359	stage V sporulation protein S
KM391_10560	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM391_10575	COG1418	mRNA catabolic process
KM391_10580	COG0488	(ABC) transporter
KM391_10595	COG0629	single-stranded DNA binding
KM391_10610	COG1413	lyase activity
KM391_10625	COG2136	Putative SAM-dependent methyltransferase
KM391_10625	COG2521	methyltransferase
KM391_10630	COG0018	arginyl-trna synthetase
KM391_10655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM391_10675	COG0017	Asparaginyl-tRNA synthetase
KM391_10695	COG1674	ftsk spoiiie
KM391_10765	COG1929	Belongs to the glycerate kinase type-1 family
KM391_10770	COG0471	metal ion transport
KM391_10775	COG0745	RESPONSE REGULATOR receiver
KM391_10780	COG3850	Histidine kinase
KM391_10780	COG5002	protein histidine kinase activity
KM391_10795	COG0733	neurotransmitter:sodium symporter activity
KM391_10820	COG2610	gluconate transmembrane transporter activity
KM391_10825	COG1454	alcohol dehydrogenase
KM391_10830	COG1794	racemase activity, acting on amino acids and derivatives
KM391_10840	COG0456	acetyltransferase
KM391_10855	COG1131	(ABC) transporter
KM391_10870	COG0546	phosphoglycolate phosphatase activity
KM391_10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_10905	COG0768	penicillin binding
KM391_10910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_10915	COG0204	Acyl-transferase
KM391_10920	COG1272	protein, Hemolysin III
KM391_10930	COG0805	protein transport
KM391_10940	COG1307	EDD domain protein, DegV family
KM391_10945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM391_10950	COG1999	signal sequence binding
KM391_10955	COG0071	Belongs to the small heat shock protein (HSP20) family
KM391_10960	COG0367	asparagine synthase
KM391_10975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_10980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_11005	COG1051	belongs to the nudix hydrolase family
KM391_11015	COG0668	transmembrane transport
KM391_11020	COG2203	Gaf domain
KM391_11020	COG4585	Histidine kinase
KM391_11025	COG2197	response regulator
KM391_11035	COG1064	alcohol dehydrogenase
KM391_11060	COG1070	Carbohydrate kinase
KM391_11065	COG1070	Carbohydrate kinase
KM391_11095	COG0517	IMP dehydrogenase activity
KM391_11095	COG1125	glycine betaine transport
KM391_11100	COG1174	glycine betaine transport
KM391_11135	COG1253	flavin adenine dinucleotide binding
KM391_11140	COG1012	belongs to the aldehyde dehydrogenase family
KM391_11145	COG5506	Protein of unknown function (DUF1694)
KM391_11160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM391_11170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM391_11175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM391_11180	COG0456	acetyltransferase
KM391_11185	COG3829	transcription factor binding
KM391_11190	COG1509	lysine 2,3-aminomutase activity
KM391_11230	COG4326	sporulation control protein
KM391_11235	COG0671	phosphoesterase, PA-phosphatase related
KM391_11240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM391_11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_11275	COG1715	Restriction endonuclease
KM391_11275	COG1787	Restriction endonuclease
KM391_11365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_11405	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM391_11405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_11410	COG2814	Major facilitator Superfamily
KM391_11415	COG4841	protein insertion into membrane
KM391_11420	COG0372	Belongs to the citrate synthase family
KM391_11425	COG2079	MmgE PrpD family protein
KM391_11430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM391_11435	COG1960	acyl-CoA dehydrogenase activity
KM391_11440	COG2084	Dehydrogenase
KM391_11450	COG1280	lysine exporter protein (LysE YggA)
KM391_11455	COG1024	Enoyl-CoA hydratase
KM391_11470	COG0420	3'-5' exonuclease activity
KM391_11475	COG0419	ATPase involved in DNA repair
KM391_11495	COG2223	nitrite transmembrane transporter activity
KM391_11500	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_11505	COG1169	isochorismate synthase
KM391_11510	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM391_11515	COG1535	isochorismatase
KM391_11515	COG3433	isochorismatase activity
KM391_11520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM391_11525	COG3251	PFAM MbtH domain protein
KM391_11530	COG2814	Major facilitator Superfamily
KM391_11545	COG0776	regulation of translation
KM391_11555	COG2318	DinB family
KM391_11565	COG1115	amino acid carrier protein
KM391_11580	COG2329	Antibiotic biosynthesis monooxygenase
KM391_11585	COG1187	pseudouridine synthase activity
KM391_11590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_11605	COG0596	Alpha beta hydrolase
KM391_11610	COG2814	Major facilitator Superfamily
KM391_11630	COG2226	methyltransferase
KM391_11675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_11710	COG1247	-acetyltransferase
KM391_11740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM391_11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_11760	COG1278	Cold shock
KM391_11775	COG0010	Belongs to the arginase family
KM391_11780	COG0561	phosphatase activity
KM391_11825	COG0583	DNA-binding transcription factor activity
KM391_11830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM391_11845	COG0583	DNA-binding transcription factor activity
KM391_11850	COG2258	MOSC domain
KM391_11865	COG1132	(ABC) transporter
KM391_11870	COG1132	(ABC) transporter
KM391_11890	COG1396	sequence-specific DNA binding
KM391_11915	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM391_11920	COG1595	DNA-templated transcription, initiation
KM391_11945	COG1649	PFAM Uncharacterised BCR, COG1649
KM391_11970	COG2971	BadF BadG BcrA BcrD
KM391_11975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_11980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM391_12000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_12030	COG1309	transcriptional regulator
KM391_12045	COG1136	(ABC) transporter
KM391_12045	COG0577	efflux transmembrane transporter activity
KM391_12050	COG0500	methyltransferase
KM391_12050	COG3615	Tellurite resistance protein tehB
KM391_12060	COG2226	methyltransferase
KM391_12065	COG3961	Belongs to the TPP enzyme family
KM391_12070	COG1846	Transcriptional regulator
KM391_12110	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM391_12125	COG1595	DNA-templated transcription, initiation
KM391_12135	COG0768	penicillin binding
KM391_12145	COG2367	Beta-lactamase
KM391_12150	COG0671	phosphoesterase, PA-phosphatase related
KM391_12155	COG1609	Transcriptional regulator
KM391_12160	COG2814	Major facilitator Superfamily
KM391_12165	COG0673	inositol 2-dehydrogenase activity
KM391_12175	COG1012	belongs to the aldehyde dehydrogenase family
KM391_12190	COG0191	fructose-bisphosphate aldolase activity
KM391_12195	COG3718	enzyme involved in inositol metabolism
KM391_12220	COG0457	Tetratricopeptide repeat
KM391_12225	COG1476	TRANSCRIPTIONal
KM391_12240	COG1876	peptidase activity
KM391_12260	COG1309	transcriptional regulator
KM391_12265	COG0488	(ABC) transporter
KM391_12280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_12295	COG1252	NADH dehydrogenase
KM391_12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_12315	COG1131	(ABC) transporter
KM391_12325	COG1309	transcriptional regulator
KM391_12340	COG1960	acyl-CoA dehydrogenase activity
KM391_12345	COG0439	Biotin carboxylase
KM391_12350	COG0511	ligase activity, forming carbon-carbon bonds
KM391_12355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM391_12360	COG1024	Enoyl-CoA hydratase
KM391_12365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM391_12370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_12380	COG1247	-acetyltransferase
KM391_12385	COG0572	uridine kinase
KM391_12395	COG2318	DinB family
KM391_12425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM391_12465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_12465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_12490	COG2814	Major facilitator Superfamily
KM391_12510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_12530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_12545	COG1063	alcohol dehydrogenase
KM391_12575	COG3773	Cell wall hydrolase
KM391_12585	COG0745	RESPONSE REGULATOR receiver
KM391_12615	COG1136	(ABC) transporter
KM391_12640	COG0460	homoserine dehydrogenase
KM391_12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_12655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM391_12720	COG2124	cytochrome p450
KM391_12755	COG0561	phosphatase activity
KM391_12765	COG5002	protein histidine kinase activity
KM391_12770	COG0768	penicillin binding
KM391_12775	COG1819	glycosyl
KM391_12780	COG1794	racemase activity, acting on amino acids and derivatives
KM391_12790	COG1122	ATPase activity
KM391_12805	COG2205	protein histidine kinase activity
KM391_12815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_12820	COG0604	alcohol dehydrogenase
KM391_12825	COG0768	penicillin binding
KM391_12835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_12870	COG0693	protein deglycase activity
KM391_12900	COG2814	Major facilitator Superfamily
KM391_12915	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_12935	COG0697	spore germination
KM391_12960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_12970	COG2223	nitrite transmembrane transporter activity
KM391_12985	COG2816	NAD+ diphosphatase activity
KM391_12990	COG0592	DNA-directed DNA polymerase activity
KM391_12995	COG1051	belongs to the nudix hydrolase family
KM391_13030	COG3878	Protein conserved in bacteria
KM391_13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM391_13090	COG0322	excinuclease ABC activity
KM391_13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_13155	COG1011	Hydrolase
KM391_13175	COG0076	glutamate decarboxylase activity
KM391_13190	COG1523	belongs to the glycosyl hydrolase 13 family
KM391_13195	COG3227	Zinc metalloprotease (Elastase)
KM391_13215	COG0201	protein transport
KM391_13225	COG0697	spore germination
KM391_13230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_13260	COG4129	membrane
KM391_13265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_13280	COG2959	enzyme of heme biosynthesis
KM391_13300	COG3483	tryptophan 2,3-dioxygenase activity
KM391_13305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM391_13310	COG3844	kynureninase activity
KM391_13315	COG1309	transcriptional regulator
KM391_13345	COG3284	Transcriptional regulator
KM391_13365	COG1349	DNA-binding transcription factor activity
KM391_13385	COG1959	2 iron, 2 sulfur cluster binding
KM391_13400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM391_13405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_13410	COG0022	dehydrogenase e1 component
KM391_13415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_13425	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_13430	COG0456	acetyltransferase
KM391_13430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_13460	COG4176	ABC-type proline glycine betaine transport system permease component
KM391_13465	COG4175	Glycine betaine
KM391_13465	COG0517	IMP dehydrogenase activity
KM391_13490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM391_13495	COG2153	protein acetylation
KM391_13500	COG3397	chitin binding
KM391_13515	COG2205	protein histidine kinase activity
KM391_13540	COG2333	competence protein COMEC
KM391_13540	COG0658	competence protein
KM391_13590	COG3973	AAA domain
KM391_13605	COG2105	PFAM AIG2 family protein
KM391_13610	COG0514	ATP-dependent DNA helicase (RecQ)
KM391_13630	COG4637	Psort location Cytoplasmic, score
KM391_13655	COG3397	chitin binding
KM391_13670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM391_13675	COG1115	amino acid carrier protein
KM391_13680	COG1012	belongs to the aldehyde dehydrogenase family
KM391_13685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM391_13695	COG3938	Belongs to the proline racemase family
KM391_13700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_13740	COG0586	Pfam SNARE associated Golgi protein
KM391_13755	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM391_13760	COG0519	Catalyzes the synthesis of GMP from XMP
KM391_13765	COG4166	transmembrane transport
KM391_13775	COG4948	Mandelate Racemase Muconate Lactonizing
KM391_13820	COG2936	dipeptidyl-peptidase activity
KM391_13825	COG5002	protein histidine kinase activity
KM391_13865	COG1164	Oligoendopeptidase f
KM391_13880	COG1307	EDD domain protein, DegV family
KM391_13900	COG2814	Major facilitator Superfamily
KM391_13910	COG1664	Polymer-forming cytoskeletal
KM391_13915	COG0789	Transcriptional regulator
KM391_13920	COG4533	DNA binding
KM391_13925	COG0477	Major facilitator Superfamily
KM391_13925	COG2814	Major facilitator Superfamily
KM391_13945	COG2261	transglycosylase associated protein
KM391_13960	COG2226	methyltransferase
KM391_13995	COG0436	Aminotransferase
KM391_14000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM391_14005	COG5146	pantothenate kinase activity
KM391_14070	COG0628	permease
KM391_14080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_14085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_14090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_14095	COG1116	anion transmembrane transporter activity
KM391_14115	COG2816	NAD+ diphosphatase activity
KM391_14135	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM391_14160	COG0697	spore germination
KM391_14165	COG2318	DinB family
KM391_14185	COG4912	Dna alkylation repair
KM391_14205	COG0861	Integral membrane protein TerC family
KM391_14210	COG1368	sulfuric ester hydrolase activity
KM391_14215	COG0488	(ABC) transporter
KM391_14225	COG2409	Drug exporters of the RND superfamily
KM391_14225	COG1033	growth of symbiont in host cell
KM391_14230	COG1033	growth of symbiont in host cell
KM391_14230	COG2409	Drug exporters of the RND superfamily
KM391_14235	COG1033	growth of symbiont in host cell
KM391_14235	COG2409	Drug exporters of the RND superfamily
KM391_14240	COG1309	transcriptional regulator
KM391_14255	COG0287	Prephenate dehydrogenase
KM391_14260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM391_14265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM391_14270	COG1605	Chorismate mutase
KM391_14270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM391_14305	COG3584	3D domain protein
KM391_14305	COG1388	LysM domain
KM391_14315	COG1595	DNA-templated transcription, initiation
KM391_14340	COG1879	ABC-type sugar transport system periplasmic component
KM391_14350	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM391_14360	COG2390	Transcriptional regulator
KM391_14395	COG2329	Antibiotic biosynthesis monooxygenase
KM391_14415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_14425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM391_14430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_14435	COG4187	Peptidase family M20/M25/M40
KM391_14440	COG1414	Transcriptional regulator
KM391_14445	COG0833	amino acid
KM391_14450	COG1690	Belongs to the RtcB family
KM391_14455	COG3239	Fatty acid desaturase
KM391_14460	COG1785	Belongs to the alkaline phosphatase family
KM391_14470	COG3655	Transcriptional regulator
KM391_14485	COG4377	Putative membrane peptidase family (DUF2324)
KM391_14495	COG3279	Response regulator of the LytR AlgR family
KM391_14505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_14510	COG0346	lactoylglutathione lyase activity
KM391_14530	COG0714	Associated with various cellular activities
KM391_14555	COG0463	Glycosyl transferase, family 2
KM391_14580	COG0463	Glycosyl transferase, family 2
KM391_14590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM391_14595	COG0753	catalase activity
KM391_14605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM391_14630	COG0714	Associated with various cellular activities
KM391_14640	COG0778	Nitroreductase
KM391_14645	COG1846	Transcriptional regulator
KM391_14680	COG1725	Transcriptional regulator
KM391_14690	COG0577	efflux transmembrane transporter activity
KM391_14690	COG1136	(ABC) transporter
KM391_14715	COG2207	Transcriptional regulator
KM391_14720	COG0456	acetyltransferase
KM391_14740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_14760	COG0642	Histidine kinase
KM391_14765	COG0745	RESPONSE REGULATOR receiver
KM391_14770	COG0596	Alpha beta hydrolase
KM391_14800	COG0730	response to heat
KM391_14810	COG0833	amino acid
KM391_14820	COG4335	DNA alkylation repair
KM391_14860	COG0768	penicillin binding
KM391_14870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM391_14900	COG1984	allophanate hydrolase subunit 2
KM391_14905	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM391_14910	COG1414	Transcriptional regulator
KM391_14925	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_14930	COG0640	Transcriptional regulator
KM391_14940	COG1960	acyl-CoA dehydrogenase activity
KM391_14955	COG3314	Sporulation integral membrane protein YlbJ
KM391_14970	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM391_14985	COG3848	Pyruvate phosphate dikinase
KM391_14985	COG0574	Belongs to the PEP-utilizing enzyme family
KM391_14990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_15005	COG5577	PFAM Coat F domain
KM391_15010	COG3403	YqcI/YcgG family
KM391_15015	COG1280	lysine exporter protein (LysE YggA)
KM391_15050	COG1063	alcohol dehydrogenase
KM391_15065	COG1027	Aspartate ammonia-lyase
KM391_15070	COG0252	asparaginase activity
KM391_15075	COG1396	sequence-specific DNA binding
KM391_15085	COG0322	excinuclease ABC activity
KM391_15090	COG0531	amino acid
KM391_15095	COG1114	Component of the transport system for branched-chain amino acids
KM391_15100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_15110	COG0281	malic enzyme
KM391_15125	COG0531	amino acid
KM391_15135	COG0784	Response regulator, receiver
KM391_15145	COG2066	Belongs to the glutaminase family
KM391_15180	COG0737	Belongs to the 5'-nucleotidase family
KM391_15185	COG0753	catalase activity
KM391_15195	COG1335	isochorismatase
KM391_15215	COG0583	DNA-binding transcription factor activity
KM391_15220	COG1846	Transcriptional regulator
KM391_15260	COG0415	Belongs to the DNA photolyase family
KM391_15265	COG0288	reversible hydration of carbon dioxide
KM391_15275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM391_15280	COG5609	conserved protein (DUF2294)
KM391_15295	COG1575	Belongs to the MenA family. Type 1 subfamily
KM391_15300	COG2267	carboxylic ester hydrolase activity
KM391_15305	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM391_15310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM391_15315	COG1121	(ABC) transporter
KM391_15345	COG0798	PFAM Bile acid sodium symporter
KM391_15350	COG0346	lactoylglutathione lyase activity
KM391_15355	COG0640	Transcriptional regulator
KM391_15370	COG0443	Heat shock 70 kDa protein
KM391_15385	COG1522	sequence-specific DNA binding
KM391_15400	COG0346	lactoylglutathione lyase activity
KM391_15425	COG2169	Transcriptional regulator
KM391_15470	COG2814	Major facilitator Superfamily
KM391_15495	COG0745	RESPONSE REGULATOR receiver
KM391_15500	COG5002	protein histidine kinase activity
KM391_15500	COG3850	Histidine kinase
KM391_15525	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM391_15545	COG1476	TRANSCRIPTIONal
KM391_15560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM391_15575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_15580	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM391_15595	COG1136	(ABC) transporter
KM391_15600	COG0577	efflux transmembrane transporter activity
KM391_15615	COG3850	Histidine kinase
KM391_15615	COG5002	protein histidine kinase activity
KM391_15625	COG2364	Membrane
KM391_15630	COG1846	Transcriptional regulator
KM391_15640	COG2808	Putative FMN-binding domain
KM391_15645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_15650	COG2271	Major facilitator Superfamily
KM391_15655	COG1556	Lactate utilization protein
KM391_15660	COG1139	Iron-sulfur cluster binding protein
KM391_15670	COG0583	DNA-binding transcription factor activity
KM391_15680	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_15700	COG0738	Major facilitator superfamily
KM391_15705	COG0673	inositol 2-dehydrogenase activity
KM391_15710	COG0561	phosphatase activity
KM391_15720	COG1609	Transcriptional regulator
KM391_15725	COG0457	Tetratricopeptide repeat
KM391_15745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_15775	COG0534	Mate efflux family protein
KM391_15795	COG2814	Major facilitator Superfamily
KM391_15800	COG1309	transcriptional regulator
KM391_15815	COG0814	amino acid
KM391_15820	COG1760	l-serine dehydratase
KM391_15825	COG1760	l-serine dehydratase
KM391_15835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM391_15840	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM391_15850	COG1335	isochorismatase
KM391_15855	COG1522	sequence-specific DNA binding
KM391_15860	COG0531	amino acid
KM391_15875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM391_15895	COG1595	DNA-templated transcription, initiation
KM391_15910	COG0662	Cupin 2, conserved barrel domain protein
KM391_15915	COG2207	Transcriptional regulator
KM391_15915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_15965	COG0477	Major facilitator Superfamily
KM391_15975	COG1846	Transcriptional regulator
KM391_15980	COG2814	Major facilitator Superfamily
KM391_15990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_15995	COG1131	(ABC) transporter
KM391_16015	COG2076	Multidrug Resistance protein
KM391_16020	COG1309	transcriptional regulator
KM391_16030	COG2031	fatty acid transporter
KM391_16040	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_16070	COG1122	ATPase activity
KM391_16075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM391_16090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM391_16095	COG1288	antiporter activity
KM391_16100	COG2356	endonuclease I
KM391_16115	COG3620	sequence-specific DNA binding
KM391_16120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_16125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM391_16130	COG0124	histidyl-tRNA synthetase
KM391_16145	COG1733	regulation of RNA biosynthetic process
KM391_16150	COG0778	Nitroreductase
KM391_16170	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_16180	COG1131	(ABC) transporter
KM391_16205	COG1011	Hydrolase
KM391_16215	COG2365	Tyrosine phosphatase family
KM391_16240	COG0346	lactoylglutathione lyase activity
KM391_16245	COG1940	carbohydrate kinase activity
KM391_16250	COG0738	Major facilitator superfamily
KM391_16255	COG0110	maltose O-acetyltransferase activity
KM391_16265	COG1136	(ABC) transporter
KM391_16265	COG0577	efflux transmembrane transporter activity
KM391_16280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM391_16285	COG0628	permease
KM391_16305	COG2226	methyltransferase
KM391_16315	COG0477	Major facilitator Superfamily
KM391_16345	COG1253	flavin adenine dinucleotide binding
KM391_16350	COG0789	Transcriptional regulator
KM391_16355	COG0697	spore germination
KM391_16360	COG1357	PFAM Pentapeptide repeats (8 copies)
KM391_16365	COG3813	Protein conserved in bacteria
KM391_16370	COG2706	6-phosphogluconolactonase activity
KM391_16375	COG1070	Carbohydrate kinase
KM391_16385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM391_16390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM391_16400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM391_16405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM391_16410	COG0604	alcohol dehydrogenase
KM391_16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_16425	COG3321	synthase
KM391_16425	COG0604	alcohol dehydrogenase
KM391_16430	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_16455	COG0656	L-ascorbic acid biosynthetic process
KM391_16460	COG2814	Major facilitator Superfamily
KM391_16475	COG0346	lactoylglutathione lyase activity
KM391_16480	COG0814	amino acid
KM391_16505	COG1393	Belongs to the ArsC family
KM391_16510	COG1733	regulation of RNA biosynthetic process
KM391_16515	COG2188	Transcriptional regulator
KM391_16525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM391_16530	COG1733	regulation of RNA biosynthetic process
KM391_16535	COG1733	regulation of RNA biosynthetic process
KM391_16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_16570	COG0384	phenazine biosynthesis protein PhzF
KM391_16580	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_16590	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_16600	COG1733	regulation of RNA biosynthetic process
KM391_16635	COG1191	sigma factor activity
KM391_16650	COG1309	transcriptional regulator
KM391_16670	COG3152	Membrane
KM391_16695	COG1151	hydroxylamine reductase activity
KM391_16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_16710	COG3757	hydrolase, family 25
KM391_16710	COG3409	Peptidoglycan-binding domain 1 protein
KM391_16745	COG2072	flavoprotein involved in K transport
KM391_16785	COG1113	amino acid transport
KM391_16790	COG2814	Major facilitator Superfamily
KM391_16820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_16825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_16845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_16850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_16855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_16860	COG3739	integral membrane protein
KM391_16865	COG0384	phenazine biosynthesis protein PhzF
KM391_16895	COG0583	DNA-binding transcription factor activity
KM391_16915	COG1193	negative regulation of DNA recombination
KM391_16935	COG1164	Oligoendopeptidase f
KM391_16940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_16970	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_16995	COG0640	Transcriptional regulator
KM391_17000	COG0604	alcohol dehydrogenase
KM391_17020	COG2808	Putative FMN-binding domain
KM391_17025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_17035	COG0385	Bile acid
KM391_17040	COG0277	FAD linked oxidase domain protein
KM391_17070	COG1216	Glycosyl transferase, family 2
KM391_17075	COG1024	Enoyl-CoA hydratase
KM391_17085	COG1285	pathogenesis
KM391_17100	COG2514	catechol 2,3-dioxygenase activity
KM391_17105	COG2720	vancomycin resistance protein
KM391_17145	COG0716	FMN binding
KM391_17175	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_17185	COG0165	Argininosuccinate lyase
KM391_17200	COG4145	pantothenate transmembrane transporter activity
KM391_17210	COG1012	belongs to the aldehyde dehydrogenase family
KM391_17215	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_17225	COG1657	PFAM Prenyltransferase squalene oxidase
KM391_17230	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM391_17235	COG2962	Rard protein
KM391_17240	COG3326	Membrane
KM391_17255	COG0489	protein tyrosine kinase activity
KM391_17265	COG0314	molybdopterin synthase activity
KM391_17270	COG0303	'Molybdopterin
KM391_17275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_17280	COG2116	formate transmembrane transporter activity
KM391_17295	COG5609	conserved protein (DUF2294)
KM391_17300	COG2427	Protein of unknown function (DUF1641)
KM391_17305	COG3383	formate dehydrogenase (NAD+) activity
KM391_17310	COG0697	spore germination
KM391_17350	COG2226	methyltransferase
KM391_17355	COG4166	transmembrane transport
KM391_17360	COG4166	transmembrane transport
KM391_17365	COG4166	transmembrane transport
KM391_17370	COG1301	dicarboxylic acid transport
KM391_17375	COG1316	TRANSCRIPTIONal
KM391_17385	COG1595	DNA-templated transcription, initiation
KM391_17405	COG1131	(ABC) transporter
KM391_17415	COG0673	inositol 2-dehydrogenase activity
KM391_17420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM391_17425	COG0187	DNA topoisomerase II activity
KM391_17430	COG1832	CoA-binding protein
KM391_17435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_17440	COG0745	RESPONSE REGULATOR receiver
KM391_17455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_17460	COG4841	protein insertion into membrane
KM391_17465	COG0824	Thioesterase
KM391_17495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_17505	COG2274	protein secretion by the type I secretion system
KM391_17510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM391_17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_17565	COG0183	Belongs to the thiolase family
KM391_17570	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_17575	COG1268	BioY protein
KM391_17580	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_17630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_17640	COG5002	protein histidine kinase activity
KM391_17645	COG0400	carboxylic ester hydrolase activity
KM391_17650	COG0346	lactoylglutathione lyase activity
KM391_17655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_17660	COG0069	glutamate synthase activity
KM391_17665	COG1902	pentaerythritol trinitrate reductase activity
KM391_17670	COG1329	Transcriptional regulator
KM391_17675	COG0010	Belongs to the arginase family
KM391_17700	COG2226	methyltransferase
KM391_17755	COG4846	Membrane protein involved in cytochrome C biogenesis
KM391_17760	COG0785	Cytochrome C biogenesis protein
KM391_17770	COG0583	DNA-binding transcription factor activity
KM391_17775	COG1380	Effector of murein hydrolase LrgA
KM391_17780	COG1346	cytolysis
KM391_17805	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM391_17805	COG3409	Peptidoglycan-binding domain 1 protein
KM391_17820	COG1132	(ABC) transporter
KM391_17825	COG1132	(ABC) transporter
KM391_17855	COG3639	organic phosphonate transmembrane transporter activity
KM391_17860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM391_17880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM391_17900	COG1695	Transcriptional regulator
KM391_17935	COG3409	Peptidoglycan-binding domain 1 protein
KM391_17935	COG1388	LysM domain
KM391_17935	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM391_17940	COG4824	toxin secretion phage lysis holin
KM391_18095	COG1595	DNA-templated transcription, initiation
KM391_18140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM391_18220	COG1396	sequence-specific DNA binding
KM391_18245	COG0174	glutamine synthetase
KM391_18250	COG0789	Transcriptional regulator
KM391_18255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM391_18265	COG2860	membrane
KM391_18275	COG0464	growth
KM391_18305	COG3584	3D domain protein
KM391_18305	COG1388	LysM domain
KM391_18310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_18310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM391_18310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM391_18315	COG1105	Belongs to the carbohydrate kinase PfkB family
KM391_18320	COG1349	DNA-binding transcription factor activity
KM391_18330	COG2322	membrane
KM391_18340	COG1113	amino acid transport
KM391_18355	COG1408	metallophosphoesterase
KM391_18360	COG2116	formate transmembrane transporter activity
KM391_18370	COG2217	Heavy metal translocating P-type atpase
KM391_18375	COG2608	mercury ion transmembrane transporter activity
KM391_18380	COG1937	Protein conserved in bacteria
KM391_18390	COG2819	hydrolase of the alpha beta superfamily
KM391_18395	COG1120	ATPase activity
KM391_18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_18415	COG0708	Exodeoxyribonuclease III
KM391_18420	COG2169	Transcriptional regulator
KM391_18425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM391_18430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM391_18440	COG2364	Membrane
KM391_18455	COG2267	carboxylic ester hydrolase activity
KM391_18460	COG0346	lactoylglutathione lyase activity
KM391_18465	COG3300	MHYT domain
KM391_18465	COG5001	Diguanylate cyclase
KM391_18480	COG1346	cytolysis
KM391_18485	COG1380	Effector of murein hydrolase LrgA
KM391_18490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_18495	COG0596	Alpha beta hydrolase
KM391_18495	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_18500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_18520	COG1404	Belongs to the peptidase S8 family
KM391_18525	COG3773	Cell wall hydrolase
KM391_18530	COG0562	UDP-galactopyranose mutase
KM391_18535	COG1368	sulfuric ester hydrolase activity
KM391_18540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_18550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM391_18575	COG1131	(ABC) transporter
KM391_18595	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM391_18600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM391_18605	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM391_18610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM391_18610	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM391_18620	COG2359	stage V sporulation protein S
KM391_18625	COG1692	metallophosphoesterase
KM391_18650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM391_18655	COG1426	Protein conserved in bacteria
KM391_18670	COG0300	oxidoreductase activity
KM391_18675	COG0612	Peptidase, M16
KM391_18680	COG0612	Peptidase, M16
KM391_18685	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM391_18695	COG3845	ABC transporter
KM391_18700	COG1744	ABC transporter substrate-binding protein PnrA-like
KM391_18705	COG2188	Transcriptional regulator
KM391_18710	COG1674	ftsk spoiiie
KM391_18720	COG0740	serine-type endopeptidase activity
KM391_18725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_18735	COG0527	aspartate kinase activity
KM391_18740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM391_18745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM391_18750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM391_18755	COG1873	PFAM PRC-barrel domain
KM391_18760	COG0612	Peptidase, M16
KM391_18765	COG0726	polysaccharide deacetylase
KM391_18780	COG0196	riboflavin kinase activity
KM391_18785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM391_18795	COG1550	Protein conserved in bacteria
KM391_18805	COG1358	cellular component organization or biogenesis
KM391_18810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM391_18815	COG0195	Participates in both transcription termination and antitermination
KM391_18835	COG0750	zinc metalloprotease
KM391_18845	COG4589	Belongs to the CDS family
KM391_18850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM391_18860	COG0528	UMP kinase activity
KM391_18890	COG4974	Belongs to the 'phage' integrase family
KM391_18900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM391_18910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM391_18950	COG1837	Belongs to the UPF0109 family
KM391_18960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM391_18970	COG0552	protein localization to endoplasmic reticulum
KM391_18975	COG1196	nuclear chromosome segregation
KM391_18985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_18990	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_18995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM391_19010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM391_19015	COG1461	Dihydroxyacetone kinase
KM391_19020	COG1302	Protein conserved in bacteria
KM391_19035	COG1564	THIamine pyrophosphokinase
KM391_19040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM391_19045	COG1162	GTPase activity
KM391_19050	COG0515	serine threonine protein kinase
KM391_19050	COG2815	serine threonine protein kinase
KM391_19055	COG0631	protein serine/threonine phosphatase activity
KM391_19065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM391_19065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM391_19075	COG0242	peptide deformylase activity
KM391_19080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM391_19085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM391_19105	COG1561	YicC-like family, N-terminal region
KM391_19110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM391_19120	COG0006	proline dipeptidase activity
KM391_19135	COG3069	C4-dicarboxylate transmembrane transporter activity
KM391_19200	COG0564	pseudouridine synthase activity
KM391_19220	COG3599	regulation of cell shape
KM391_19225	COG2302	S4 RNA-binding domain
KM391_19230	COG0762	integral membrane protein
KM391_19240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM391_19245	COG1496	oxidoreductase activity
KM391_19250	COG1873	PFAM PRC-barrel domain
KM391_19255	COG1191	sigma factor activity
KM391_19260	COG1191	sigma factor activity
KM391_19270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM391_19275	COG0849	cell division
KM391_19280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM391_19285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM391_19295	COG0772	Belongs to the SEDS family
KM391_19310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM391_19315	COG0768	penicillin binding
KM391_19320	COG0768	penicillin binding
KM391_19325	COG4839	cell division protein FtsL
KM391_19340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM391_19355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM391_19360	COG1399	metal-binding, possibly nucleic acid-binding protein
KM391_19410	COG4824	toxin secretion phage lysis holin
KM391_19495	COG1802	Transcriptional regulator
KM391_19495	COG4626	Terminase
KM391_19520	COG0582	viral genome integration into host DNA
KM391_19585	COG0756	dUTP diphosphatase activity
KM391_19600	COG1191	sigma factor activity
KM391_19625	COG1484	DNA-dependent DNA replication
KM391_19655	COG1396	sequence-specific DNA binding
KM391_19670	COG1396	sequence-specific DNA binding
KM391_19685	COG0582	viral genome integration into host DNA
KM391_19695	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM391_19700	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM391_19705	COG3314	Sporulation integral membrane protein YlbJ
KM391_19715	COG0742	ribosomal rna small subunit methyltransferase
KM391_19730	COG3679	Belongs to the UPF0342 family
KM391_19735	COG0406	alpha-ribazole phosphatase activity
KM391_19750	COG2340	Cysteine-rich secretory protein family
KM391_19765	COG3336	cytochrome c oxidase
KM391_19800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM391_19805	COG0772	Belongs to the SEDS family
KM391_19815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM391_19820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM391_19830	COG4896	Protein conserved in bacteria
KM391_19845	COG1217	gtp-binding protein TYPA
KM391_19855	COG0483	inositol monophosphate 1-phosphatase activity
KM391_19875	COG1982	Orn Lys Arg decarboxylase major
KM391_19920	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_19925	COG0022	dehydrogenase e1 component
KM391_19930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_19940	COG0242	peptide deformylase activity
KM391_19945	COG0561	phosphatase activity
KM391_19955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_19960	COG0569	domain protein
KM391_19980	COG0583	DNA-binding transcription factor activity
KM391_19985	COG0517	IMP dehydrogenase activity
KM391_19995	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM391_20005	COG4703	Protein of unknown function (DUF1797)
KM391_20020	COG2200	EAL domain
KM391_20025	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_20030	COG1408	metallophosphoesterase
KM391_20040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM391_20075	COG2814	Major facilitator Superfamily
KM391_20095	COG3209	COG3209 Rhs family protein
KM391_20105	COG2205	protein histidine kinase activity
KM391_20115	COG0436	Aminotransferase
KM391_20120	COG1609	Transcriptional regulator
KM391_20125	COG3833	ABC-type maltose transport systems, permease component
KM391_20130	COG1175	transmembrane transport
KM391_20135	COG2182	Extracellular solute-binding protein
KM391_20145	COG0366	Alpha amylase catalytic
KM391_20150	COG3842	ATPase activity
KM391_20190	COG0183	Belongs to the thiolase family
KM391_20225	COG1695	Transcriptional regulator
KM391_20230	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_20240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM391_20250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM391_20255	COG0436	Aminotransferase
KM391_20275	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM391_20295	COG2199	diguanylate cyclase activity
KM391_20300	COG0778	Nitroreductase
KM391_20325	COG2190	(PTS) system
KM391_20325	COG1263	PTS System
KM391_20325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_20330	COG3711	transcriptional antiterminator
KM391_20340	COG2188	Transcriptional regulator
KM391_20350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM391_20375	COG1547	Domain of unknown function (DUF309)
KM391_20380	COG0456	acetyltransferase
KM391_20385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM391_20390	COG4086	secreted protein
KM391_20395	COG0561	phosphatase activity
KM391_20400	COG0697	spore germination
KM391_20415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_20440	COG0733	neurotransmitter:sodium symporter activity
KM391_20460	COG1686	Belongs to the peptidase S11 family
KM391_20465	COG1725	Transcriptional regulator
KM391_20470	COG1131	(ABC) transporter
KM391_20485	COG1846	Transcriptional regulator
KM391_20500	COG0598	Magnesium transport protein CorA
KM391_20525	COG4974	Belongs to the 'phage' integrase family
KM391_20535	COG0735	belongs to the Fur family
KM391_20540	COG1300	Membrane
KM391_20560	COG0667	Aldo Keto reductase
KM391_20565	COG0656	L-ascorbic acid biosynthetic process
KM391_20570	COG0456	acetyltransferase
KM391_20570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_20580	COG4085	toxin activity
KM391_20580	COG1525	nuclease
KM391_20580	COG0737	Belongs to the 5'-nucleotidase family
KM391_20590	COG0596	Alpha beta hydrolase
KM391_20595	COG2056	Na+-H+ antiporter family
KM391_20600	COG1609	Transcriptional regulator
KM391_20605	COG0456	acetyltransferase
KM391_20610	COG1073	alpha beta
KM391_20625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM391_20625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM391_20630	COG0307	riboflavin synthase, alpha
KM391_20655	COG4106	trans-aconitate 2-methyltransferase activity
KM391_20660	COG2226	methyltransferase
KM391_20660	COG1073	alpha beta
KM391_20675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_20685	COG1757	Na H antiporter
KM391_20690	COG0737	Belongs to the 5'-nucleotidase family
KM391_20700	COG1522	sequence-specific DNA binding
KM391_20720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM391_20730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM391_20745	COG0300	oxidoreductase activity
KM391_20755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_20760	COG1760	l-serine dehydratase
KM391_20765	COG1760	l-serine dehydratase
KM391_20785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_20795	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM391_20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_20815	COG1376	ErfK ybiS ycfS ynhG family protein
KM391_20820	COG4129	membrane
KM391_20825	COG1126	abc transporter atp-binding protein
KM391_20830	COG0765	amino acid transport
KM391_20835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_20855	COG0772	Belongs to the SEDS family
KM391_20860	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_20865	COG0022	dehydrogenase e1 component
KM391_20870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM391_20890	COG0280	phosphate acetyltransferase
KM391_20895	COG3829	transcription factor binding
KM391_20895	COG3290	protein histidine kinase activity
KM391_20905	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_20910	COG3093	addiction module antidote protein HigA
KM391_20920	COG0745	RESPONSE REGULATOR receiver
KM391_20925	COG0750	zinc metalloprotease
KM391_20930	COG0497	DNA recombination
KM391_20940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM391_20950	COG0142	geranyltranstransferase activity
KM391_20975	COG1302	Protein conserved in bacteria
KM391_20980	COG0439	Biotin carboxylase
KM391_20985	COG0511	ligase activity, forming carbon-carbon bonds
KM391_21030	COG3854	ATPases associated with a variety of cellular activities
KM391_21055	COG0006	proline dipeptidase activity
KM391_21070	COG3872	metal-dependent enzyme
KM391_21080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM391_21100	COG0095	Lipoate-protein ligase
KM391_21105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_21110	COG1609	Transcriptional regulator
KM391_21120	COG2076	Multidrug Resistance protein
KM391_21125	COG2076	Multidrug Resistance protein
KM391_21160	COG1131	(ABC) transporter
KM391_21165	COG1725	Transcriptional regulator
KM391_21195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_21250	COG4970	Tfp pilus assembly protein FimT
KM391_21260	COG1459	type II secretion system
KM391_21265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM391_21315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM391_21320	COG0646	methionine synthase
KM391_21320	COG1410	methionine synthase
KM391_21325	COG0646	methionine synthase
KM391_21325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM391_21330	COG0626	cystathionine gamma-synthase activity
KM391_21335	COG0626	cystathionine gamma-synthase activity
KM391_21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_21365	COG1940	carbohydrate kinase activity
KM391_21370	COG4483	Protein conserved in bacteria
KM391_21375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM391_21380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM391_21385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM391_21390	COG0704	Plays a role in the regulation of phosphate uptake
KM391_21400	COG0581	inorganic phosphate transmembrane transporter activity
KM391_21405	COG0573	inorganic phosphate transmembrane transporter activity
KM391_21410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM391_21415	COG0768	penicillin binding
KM391_21420	COG0477	Major facilitator Superfamily
KM391_21425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_21450	COG0735	belongs to the Fur family
KM391_21455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM391_21460	COG1121	(ABC) transporter
KM391_21465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_21495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM391_21500	COG2384	SAM-dependent methyltransferase
KM391_21505	COG2010	Cytochrome c
KM391_21510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM391_21515	COG0358	DNA primase activity
KM391_21525	COG0517	IMP dehydrogenase activity
KM391_21540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM391_21545	COG0295	cytidine deaminase activity
KM391_21550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM391_21560	COG1480	7TM receptor with intracellular HD hydrolase
KM391_21565	COG1702	phosphate starvation-inducible protein PhoH
KM391_21580	COG1610	YqeY-like protein
KM391_21585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM391_21590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM391_21595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM391_21625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM391_21630	COG1733	regulation of RNA biosynthetic process
KM391_21655	COG1466	dna polymerase III delta subunit
KM391_21665	COG0658	competence protein
KM391_21665	COG2333	competence protein COMEC
KM391_21670	COG2131	deaminase
KM391_21675	COG1596	polysaccharide export
KM391_21675	COG1555	photosystem II stabilization
KM391_21680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_21685	COG2226	methyltransferase
KM391_21690	COG0799	negative regulation of ribosome biogenesis
KM391_21695	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM391_21705	COG1534	Rna-binding protein
KM391_21715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM391_21720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM391_21745	COG1595	DNA-templated transcription, initiation
KM391_21755	COG0778	Nitroreductase
KM391_21760	COG2357	RelA SpoT domain protein
KM391_21770	COG1785	Belongs to the alkaline phosphatase family
KM391_21780	COG2267	carboxylic ester hydrolase activity
KM391_21815	COG1404	Belongs to the peptidase S8 family
KM391_21820	COG3186	Phenylalanine-4-hydroxylase
KM391_21835	COG2259	Doxx family
KM391_21875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_21885	COG1012	belongs to the aldehyde dehydrogenase family
KM391_21885	COG1454	alcohol dehydrogenase
KM391_21890	COG0626	cystathionine gamma-synthase activity
KM391_21895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_21920	COG0768	penicillin binding
KM391_21935	COG0826	peptidase U32
KM391_21940	COG0826	peptidase U32
KM391_21945	COG4122	O-methyltransferase activity
KM391_21950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM391_21970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_21980	COG0628	permease
KM391_22000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM391_22010	COG0482	sulfurtransferase activity
KM391_22015	COG1104	cysteine desulfurase activity
KM391_22020	COG1959	2 iron, 2 sulfur cluster binding
KM391_22025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM391_22035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM391_22060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM391_22070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM391_22070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM391_22075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM391_22080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM391_22080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM391_22090	COG2244	polysaccharide biosynthetic process
KM391_22095	COG2323	membrane
KM391_22105	COG1862	Preprotein translocase
KM391_22135	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM391_22145	COG0697	spore germination
KM391_22150	COG0697	spore germination
KM391_22155	COG0640	Transcriptional regulator
KM391_22180	COG0157	Belongs to the NadC ModD family
KM391_22185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM391_22190	COG1104	cysteine desulfurase activity
KM391_22195	COG1827	regulation of RNA biosynthetic process
KM391_22200	COG2258	MOSC domain
KM391_22205	COG0077	Prephenate dehydratase
KM391_22210	COG0577	efflux transmembrane transporter activity
KM391_22215	COG0577	efflux transmembrane transporter activity
KM391_22220	COG1136	(ABC) transporter
KM391_22230	COG0745	RESPONSE REGULATOR receiver
KM391_22235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM391_22240	COG3290	protein histidine kinase activity
KM391_22250	COG2868	ribosomal protein
KM391_22260	COG1530	ribonuclease E activity
KM391_22265	COG1994	Peptidase M50
KM391_22270	COG0739	heme binding
KM391_22275	COG2894	cell division
KM391_22295	COG1077	Cell shape determining protein MreB Mrl
KM391_22315	COG0285	dihydrofolate synthase activity
KM391_22320	COG0525	valine-tRNA ligase activity
KM391_22330	COG1388	LysM domain
KM391_22340	COG0113	porphobilinogen synthase activity
KM391_22345	COG1587	Uroporphyrinogen-III synthase
KM391_22355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM391_22365	COG1846	Transcriptional regulator
KM391_22370	COG1764	response to oxidative stress
KM391_22385	COG1067	ATP-dependent peptidase activity
KM391_22385	COG0470	DNA polymerase III
KM391_22430	COG0622	Phosphoesterase
KM391_22445	COG5401	PFAM Sporulation and spore germination
KM391_22465	COG1309	transcriptional regulator
KM391_22480	COG2197	response regulator
KM391_22485	COG2233	PERMEase
KM391_22495	COG0402	S-adenosylhomocysteine deaminase activity
KM391_22500	COG0402	S-adenosylhomocysteine deaminase activity
KM391_22510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_22520	COG0444	Belongs to the ABC transporter superfamily
KM391_22525	COG4608	Belongs to the ABC transporter superfamily
KM391_22530	COG3275	phosphorelay sensor kinase activity
KM391_22535	COG3279	Response regulator of the LytR AlgR family
KM391_22550	COG1983	PspC domain protein
KM391_22555	COG1396	sequence-specific DNA binding
KM391_22560	COG0697	spore germination
KM391_22570	COG1959	2 iron, 2 sulfur cluster binding
KM391_22575	COG1668	transmembrane transport
KM391_22580	COG4152	abc transporter atp-binding protein
KM391_22585	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM391_22595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM391_22600	COG1876	peptidase activity
KM391_22605	COG0824	Thioesterase
KM391_22610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM391_22615	COG1053	succinate dehydrogenase
KM391_22620	COG2009	succinate dehydrogenase
KM391_22625	COG1719	4-vinyl reductase, 4VR
KM391_22635	COG3118	belongs to the thioredoxin family
KM391_22640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM391_22645	COG2086	electron transfer activity
KM391_22650	COG1024	Enoyl-CoA hydratase
KM391_22655	COG1309	transcriptional regulator
KM391_22660	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_22680	COG2318	DinB family
KM391_22710	COG1131	(ABC) transporter
KM391_22715	COG2205	protein histidine kinase activity
KM391_22720	COG0745	RESPONSE REGULATOR receiver
KM391_22730	COG4895	conserved protein (DUF2196)
KM391_22735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM391_22750	COG4509	Sortase family
KM391_22755	COG1120	ATPase activity
KM391_22770	COG5386	Cell surface protein
KM391_22780	COG5386	Cell surface protein
KM391_22785	COG1114	Component of the transport system for branched-chain amino acids
KM391_22790	COG1187	pseudouridine synthase activity
KM391_22800	COG1796	DNA polymerase
KM391_22800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM391_22805	COG1286	toxin biosynthetic process
KM391_22850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM391_22860	COG1418	mRNA catabolic process
KM391_22885	COG2814	Major facilitator Superfamily
KM391_22890	COG1566	PFAM secretion protein HlyD family protein
KM391_22895	COG1309	transcriptional regulator
KM391_22900	COG1363	Peptidase, m42
KM391_22925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_22935	COG1484	DNA-dependent DNA replication
KM391_22940	COG3611	Membrane attachment protein
KM391_22950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM391_22955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM391_22960	COG0237	dephospho-CoA kinase activity
KM391_22965	COG1971	Probably functions as a manganese efflux pump
KM391_22975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_22975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_22980	COG5002	protein histidine kinase activity
KM391_22985	COG0745	RESPONSE REGULATOR receiver
KM391_23005	COG0538	isocitrate dehydrogenase activity
KM391_23010	COG0372	Belongs to the citrate synthase family
KM391_23020	COG0628	permease
KM391_23025	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM391_23050	COG1725	Transcriptional regulator
KM391_23055	COG0281	malic enzyme
KM391_23060	COG0587	DNA-directed DNA polymerase activity
KM391_23075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM391_23095	COG4109	DRTGG domain
KM391_23110	COG0006	proline dipeptidase activity
KM391_23145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_23150	COG0662	Cupin 2, conserved barrel domain protein
KM391_23160	COG1476	TRANSCRIPTIONal
KM391_23175	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_23180	COG0589	response to stress
KM391_23220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_23240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM391_23245	COG0827	DNA restriction-modification system
KM391_23250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM391_23255	COG3874	Sporulation protein YtfJ
KM391_23270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM391_23280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_23295	COG1104	cysteine desulfurase activity
KM391_23305	COG0583	DNA-binding transcription factor activity
KM391_23310	COG0697	spore germination
KM391_23320	COG1956	GAF domain-containing protein
KM391_23325	COG0626	cystathionine gamma-synthase activity
KM391_23355	COG1595	DNA-templated transcription, initiation
KM391_23365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_23370	COG0454	-acetyltransferase
KM391_23375	COG0517	IMP dehydrogenase activity
KM391_23380	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM391_23390	COG0745	RESPONSE REGULATOR receiver
KM391_23400	COG0666	response to abiotic stimulus
KM391_23435	COG1609	Transcriptional regulator
KM391_23440	COG4851	CamS sex pheromone cAM373 precursor
KM391_23445	COG3118	belongs to the thioredoxin family
KM391_23455	COG2309	aminopeptidase activity
KM391_23475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_23490	COG1674	ftsk spoiiie
KM391_23500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_23505	COG4848	Belongs to the UPF0354 family
KM391_23510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_23515	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM391_23520	COG1363	Peptidase, m42
KM391_23530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_23545	COG0510	thiamine kinase activity
KM391_23550	COG1523	belongs to the glycosyl hydrolase 13 family
KM391_23565	COG1349	DNA-binding transcription factor activity
KM391_23570	COG1187	pseudouridine synthase activity
KM391_23575	COG2244	polysaccharide biosynthetic process
KM391_23580	COG2081	HI0933 family
KM391_23585	COG2814	Major facilitator Superfamily
KM391_23595	COG3832	glyoxalase III activity
KM391_23615	COG1329	Transcriptional regulator
KM391_23625	COG4975	Glucose uptake
KM391_23640	COG0314	molybdopterin synthase activity
KM391_23645	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM391_23650	COG0303	'Molybdopterin
KM391_23660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_23685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_23695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM391_23735	COG2814	Major facilitator Superfamily
KM391_23740	COG0475	glutathione-regulated potassium exporter activity
KM391_23745	COG0490	domain, Protein
KM391_23750	COG0582	viral genome integration into host DNA
KM391_23760	COG1136	(ABC) transporter
KM391_23780	COG1242	4 iron, 4 sulfur cluster binding
KM391_23785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM391_23790	COG1131	(ABC) transporter
KM391_23800	COG1794	racemase activity, acting on amino acids and derivatives
KM391_23820	COG2267	carboxylic ester hydrolase activity
KM391_23825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM391_23830	COG0671	phosphoesterase, PA-phosphatase related
KM391_23835	COG0438	transferase activity, transferring glycosyl groups
KM391_23845	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM391_23900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM391_23905	COG5002	protein histidine kinase activity
KM391_23910	COG4191	Histidine kinase
KM391_23915	COG2267	carboxylic ester hydrolase activity
KM391_23920	COG1368	sulfuric ester hydrolase activity
KM391_23935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_23940	COG1116	anion transmembrane transporter activity
KM391_23945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_23970	COG0494	nUDIX hydrolase
KM391_24000	COG0288	reversible hydration of carbon dioxide
KM391_24005	COG1271	oxidase subunit
KM391_24010	COG1294	oxidase, subunit
KM391_24030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_24055	COG1842	Phage shock protein A
KM391_24085	COG5002	protein histidine kinase activity
KM391_24090	COG0745	RESPONSE REGULATOR receiver
KM391_24120	COG1597	lipid kinase activity
KM391_24155	COG0586	Pfam SNARE associated Golgi protein
KM391_24165	COG0577	efflux transmembrane transporter activity
KM391_24170	COG1136	(ABC) transporter
KM391_24175	COG3708	Transcriptional regulator
KM391_24175	COG2207	Transcriptional regulator
KM391_24180	COG0745	RESPONSE REGULATOR receiver
KM391_24185	COG2205	protein histidine kinase activity
KM391_24195	COG0577	efflux transmembrane transporter activity
KM391_24200	COG1136	(ABC) transporter
KM391_24220	COG2188	Transcriptional regulator
KM391_24240	COG3964	amidohydrolase
KM391_24270	COG4948	Mandelate Racemase Muconate Lactonizing
KM391_24280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM391_24285	COG0596	Alpha beta hydrolase
KM391_24290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM391_24295	COG1169	isochorismate synthase
KM391_24300	COG1575	Belongs to the MenA family. Type 1 subfamily
KM391_24305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM391_24325	COG0058	SHG alpha-glucan phosphorylase activity
KM391_24330	COG0297	glycogen (starch) synthase activity
KM391_24335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM391_24455	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM391_24490	COG1285	pathogenesis
KM391_24495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM391_24505	COG0166	Belongs to the GPI family
KM391_24510	COG2155	Conserved Protein
KM391_24515	COG1098	S1 RNA binding domain
KM391_24520	COG0436	Aminotransferase
KM391_24525	COG1522	sequence-specific DNA binding
KM391_24530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM391_24535	COG2267	carboxylic ester hydrolase activity
KM391_24545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM391_24565	COG5018	Exonuclease
KM391_24570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_24590	COG2050	protein possibly involved in aromatic compounds catabolism
KM391_24600	COG1268	BioY protein
KM391_24610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM391_24615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM391_24630	COG3584	3D domain protein
KM391_24645	COG1252	NADH dehydrogenase
KM391_24660	COG3708	Transcriptional regulator
KM391_24675	COG1683	Conserved Protein
KM391_24695	COG0316	Belongs to the HesB IscA family
KM391_24710	COG1252	NADH dehydrogenase
KM391_24725	COG0390	transport system, permease component
KM391_24730	COG2824	Alkylphosphonate utilization operon protein PhnA
KM391_24770	COG4837	Protein of unknown function (DUF1462)
KM391_24775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM391_24785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_24790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM391_24800	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_24805	COG0647	UMP catabolic process
KM391_24815	COG2445	Protein of unknown function DUF86
KM391_24820	COG1494	fructose-1,6-bisphosphatase
KM391_24835	COG4470	Protein conserved in bacteria
KM391_24845	COG0789	Transcriptional regulator
KM391_24850	COG4377	Putative membrane peptidase family (DUF2324)
KM391_24875	COG0739	heme binding
KM391_24885	COG3377	Domain of unknown function (DUF1805)
KM391_24890	COG0737	Belongs to the 5'-nucleotidase family
KM391_24895	COG1695	Transcriptional regulator
KM391_24905	COG0719	Fe-S assembly protein
KM391_24910	COG0822	iron-sulfur transferase activity
KM391_24915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM391_24920	COG0719	Fe-S assembly protein
KM391_24925	COG0396	ATPase activity
KM391_24930	COG1464	Belongs to the NlpA lipoprotein family
KM391_24935	COG1464	Belongs to the NlpA lipoprotein family
KM391_24940	COG2011	ABC-type metal ion transport system permease component
KM391_24945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_24955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_24960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM391_24970	COG1393	Belongs to the ArsC family
KM391_25015	COG0039	L-malate dehydrogenase activity
KM391_25035	COG1309	transcriptional regulator
KM391_25040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_25045	COG1960	acyl-CoA dehydrogenase activity
KM391_25050	COG0183	Belongs to the thiolase family
KM391_25055	COG1024	Enoyl-CoA hydratase
KM391_25055	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM391_25065	COG1686	Belongs to the peptidase S11 family
KM391_25080	COG0011	TIGRFAM Protein of
KM391_25085	COG0840	transmembrane signaling receptor activity
KM391_25105	COG2814	Major facilitator Superfamily
KM391_25110	COG0531	amino acid
KM391_25120	COG0706	membrane insertase activity
KM391_25130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_25165	COG0586	Pfam SNARE associated Golgi protein
KM391_25175	COG1376	ErfK ybiS ycfS ynhG family protein
KM391_25180	COG0745	RESPONSE REGULATOR receiver
KM391_25185	COG5002	protein histidine kinase activity
KM391_25210	COG2151	metal-sulfur cluster biosynthetic enzyme
KM391_25215	COG3227	Zinc metalloprotease (Elastase)
KM391_25220	COG1741	Belongs to the pirin family
KM391_25235	COG0475	glutathione-regulated potassium exporter activity
KM391_25240	COG0490	domain, Protein
KM391_25245	COG1115	amino acid carrier protein
KM391_25250	COG0783	Belongs to the Dps family
KM391_25265	COG1611	Belongs to the LOG family
KM391_25285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_25290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_25295	COG1115	amino acid carrier protein
KM391_25300	COG1115	amino acid carrier protein
KM391_25305	COG2910	NAD(P)H-binding
KM391_25320	COG0656	L-ascorbic acid biosynthetic process
KM391_25325	COG2814	Major facilitator Superfamily
KM391_25330	COG1733	regulation of RNA biosynthetic process
KM391_25340	COG1252	NADH dehydrogenase
KM391_25345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM391_25350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM391_25360	COG0840	transmembrane signaling receptor activity
KM391_25360	COG3290	protein histidine kinase activity
KM391_25370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM391_25375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM391_25390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_25445	COG0557	exoribonuclease II activity
KM391_25450	COG1647	Serine aminopeptidase, S33
KM391_25455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM391_25460	COG1346	cytolysis
KM391_25560	COG4695	Portal protein
KM391_25585	COG4974	Belongs to the 'phage' integrase family
KM391_25595	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM391_25600	COG0149	triose-phosphate isomerase activity
KM391_25610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM391_25625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM391_25650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_25665	COG2323	membrane
KM391_25670	COG0740	serine-type endopeptidase activity
KM391_25675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_25685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM391_25695	COG1051	belongs to the nudix hydrolase family
KM391_25705	COG0492	ferredoxin-NADP+ reductase activity
KM391_25710	COG0457	Tetratricopeptide repeat
KM391_25715	COG0110	maltose O-acetyltransferase activity
KM391_25735	COG1950	PFAM Membrane protein of
KM391_25745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_25750	COG0556	nucleotide-excision repair
KM391_25770	COG0789	Transcriptional regulator
KM391_25795	COG2855	membrane
KM391_25800	COG0583	DNA-binding transcription factor activity
KM391_25810	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM391_25815	COG0488	(ABC) transporter
KM391_25825	COG1132	(ABC) transporter
KM391_25830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_25835	COG0793	Belongs to the peptidase S41A family
KM391_25835	COG3409	Peptidoglycan-binding domain 1 protein
KM391_25840	COG2177	Part of the ABC transporter FtsEX involved in
KM391_25845	COG2884	Cell division ATP-binding protein ftsE
KM391_25860	COG0653	protein targeting
KM391_25865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM391_25870	COG1278	Cold shock
KM391_25875	COG1040	competence protein
KM391_25880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM391_25885	COG0791	NLP P60 protein
KM391_25885	COG1388	LysM domain
KM391_25890	COG1733	regulation of RNA biosynthetic process
KM391_25895	COG1307	EDD domain protein, DegV family
KM391_25900	COG1739	Uncharacterized protein family UPF0029
KM391_25905	COG1316	TRANSCRIPTIONal
KM391_25910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM391_25915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM391_25920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM391_25930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM391_25930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM391_25945	COG3394	polysaccharide catabolic process
KM391_25950	COG1486	melibiose metabolic process
KM391_25955	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_25960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_25970	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM391_25975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM391_25980	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_25990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_25995	COG1301	dicarboxylic acid transport
KM391_26005	COG0346	lactoylglutathione lyase activity
KM391_26010	COG1511	domain protein
KM391_26015	COG0583	DNA-binding transcription factor activity
KM391_26020	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM391_26040	COG1271	oxidase subunit
KM391_26045	COG1294	oxidase, subunit
KM391_26050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_26060	COG1620	l-lactate permease
KM391_26070	COG2389	metal-binding protein
KM391_26080	COG1368	sulfuric ester hydrolase activity
KM391_26095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_26110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_26115	COG1388	LysM domain
KM391_26115	COG3584	3D domain protein
KM391_26140	COG4715	Zinc finger, swim domain protein
KM391_26145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_26185	COG0577	efflux transmembrane transporter activity
KM391_26190	COG1136	(ABC) transporter
KM391_26225	COG5002	protein histidine kinase activity
KM391_26230	COG0745	RESPONSE REGULATOR receiver
KM391_26235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM391_26250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM391_26255	COG1134	teichoic acid transport
KM391_26260	COG1682	transport, permease protein
KM391_26265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM391_26310	COG1609	Transcriptional regulator
KM391_26325	COG0739	heme binding
KM391_26345	COG2385	sporulation resulting in formation of a cellular spore
KM391_26360	COG4836	Membrane
KM391_26365	COG1007	ATP synthesis coupled electron transport
KM391_26370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM391_26375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM391_26385	COG0839	Belongs to the complex I subunit 6 family
KM391_26400	COG0649	NAD binding
KM391_26405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM391_26420	COG3300	MHYT domain
KM391_26420	COG5001	Diguanylate cyclase
KM391_26470	COG0356	it plays a direct role in the translocation of protons across the membrane
KM391_26505	COG0698	ribose 5-phosphate isomerase
KM391_26515	COG2190	(PTS) system
KM391_26520	COG2259	Doxx family
KM391_26525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM391_26540	COG0009	L-threonylcarbamoyladenylate synthase
KM391_26555	COG2890	protein-(glutamine-N5) methyltransferase activity
KM391_26575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM391_26580	COG1494	fructose-1,6-bisphosphatase
KM391_26600	COG4821	SIS domain
KM391_26610	COG3343	RNA polymerase activity
KM391_26620	COG1960	acyl-CoA dehydrogenase activity
KM391_26625	COG1960	acyl-CoA dehydrogenase activity
KM391_26630	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM391_26635	COG0183	Belongs to the thiolase family
KM391_26640	COG0247	lactate metabolic process
KM391_26640	COG2181	nitrate reductase activity
KM391_26645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_26655	COG3300	MHYT domain
KM391_26655	COG5001	Diguanylate cyclase
KM391_26675	COG2197	response regulator
KM391_26680	COG4585	Histidine kinase
KM391_26685	COG0842	Transport permease protein
KM391_26690	COG1131	(ABC) transporter
KM391_26695	COG0024	Methionine aminopeptidase
KM391_26705	COG2234	aminopeptidase activity
KM391_26725	COG1595	DNA-templated transcription, initiation
KM391_26730	COG0018	arginyl-trna synthetase
KM391_26735	COG4506	Protein conserved in bacteria
KM391_26740	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_26755	COG0010	Belongs to the arginase family
KM391_26765	COG2814	Major facilitator Superfamily
KM391_26770	COG0789	Transcriptional regulator
KM391_26775	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_26780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_26790	COG1994	Peptidase M50
KM391_26800	COG1078	dGTPase activity
KM391_26805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_26810	COG1120	ATPase activity
KM391_26815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_26840	COG0095	Lipoate-protein ligase
KM391_26845	COG0280	phosphate acetyltransferase
KM391_26860	COG3773	Cell wall hydrolase
KM391_26870	COG2363	Small membrane protein
KM391_26885	COG2233	PERMEase
KM391_26890	COG0561	phosphatase activity
KM391_26895	COG2814	Major facilitator Superfamily
KM391_26905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_26910	COG1131	(ABC) transporter
KM391_26915	COG2755	lipolytic protein G-D-S-L family
KM391_26920	COG1609	Transcriptional regulator
KM391_26930	COG0460	homoserine dehydrogenase
KM391_26940	COG2873	o-acetylhomoserine
KM391_26950	COG1011	Hydrolase
KM391_26955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM391_26965	COG2197	response regulator
KM391_26975	COG0351	phosphomethylpyrimidine kinase
KM391_26980	COG3706	GGDEF domain
KM391_26985	COG2879	small protein
KM391_26990	COG1966	Carbon starvation protein
KM391_26995	COG3279	Response regulator of the LytR AlgR family
KM391_27000	COG0477	Major facilitator Superfamily
KM391_27025	COG0840	transmembrane signaling receptor activity
KM391_27035	COG1607	acyl-coa hydrolase
KM391_27050	COG0488	(ABC) transporter
KM391_27070	COG0463	Glycosyl transferase, family 2
KM391_27075	COG1309	transcriptional regulator
KM391_27080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM391_27085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_27085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_27090	COG0628	permease
KM391_27105	COG3279	Response regulator of the LytR AlgR family
KM391_27110	COG3275	phosphorelay sensor kinase activity
KM391_27115	COG2814	Major facilitator Superfamily
KM391_27120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_27125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM391_27130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_27150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM391_27155	COG1272	protein, Hemolysin III
KM391_27175	COG0516	GMP reductase activity
KM391_27180	COG1164	Oligoendopeptidase f
KM391_27200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_27205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM391_27210	COG4853	Protein conserved in bacteria
KM391_27215	COG4863	YycH protein
KM391_27220	COG5002	protein histidine kinase activity
KM391_27225	COG0745	RESPONSE REGULATOR receiver
KM391_27255	COG0305	Participates in initiation and elongation during chromosome replication
KM391_27265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM391_27270	COG4241	membrane
KM391_27280	COG0629	single-stranded DNA binding
KM391_27290	COG0012	GTP binding
KM391_27295	COG4481	Protein conserved in bacteria
KM391_27300	COG0668	transmembrane transport
KM391_27310	COG1475	DNA binding
KM391_27315	COG1192	Involved in chromosome partitioning
KM391_27340	COG1847	R3H domain protein
KM391_27345	COG0706	membrane insertase activity
KM391_27355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM391_27405	COG3344	reverse transcriptase
KM391_27485	COG3344	reverse transcriptase
KM391_27675	COG4962	Type ii secretion system protein e
KM391_27810	COG2311	Membrane
KM391_27830	COG4196	transglutaminase domain protein
KM391_27835	COG0671	phosphoesterase, PA-phosphatase related
KM391_27850	COG1215	transferase activity, transferring glycosyl groups
KM391_27855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM391_27860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM391_28020	COG2002	toxin-antitoxin pair type II binding
KM391_28030	COG4974	Belongs to the 'phage' integrase family
KM391_28085	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM391_28095	COG4974	Belongs to the 'phage' integrase family
KM391_28120	COG0457	Tetratricopeptide repeat
KM391_28325	COG0741	lytic transglycosylase activity
KM391_28325	COG0791	NLP P60 protein
KM391_28390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM391_28450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_28460	COG4166	transmembrane transport
KM391_28500	COG1280	lysine exporter protein (LysE YggA)
KM391_28525	COG0681	Belongs to the peptidase S26 family
KM391_28600	COG1309	transcriptional regulator
KM391_28605	COG1683	Conserved Protein
KM391_28645	COG1192	Involved in chromosome partitioning