locus-tag class description BVB96_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BVB96_00015 ENOG410848D S4 domain protein YaaA BVB96_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVB96_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BVB96_00100 ENOG4105ZMH deoxynucleoside kinase BVB96_00110 ENOG4105GTG Isochorismatase BVB96_00120 ENOG4108Z6B deaminase BVB96_00130 ENOG4105C6E dna polymerase iii BVB96_00150 ENOG41067KS pro-sigma K processing BVB96_00185 ENOG4105CXN decarboxylase BVB96_00195 ENOG4105FA2 dna polymerase iii BVB96_00200 ENOG4105MA4 psp1 domain protein BVB96_00210 ENOG41060K3 Methyltransferase BVB96_00220 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BVB96_00225 ENOG4105KRN Transcriptional regulator, abrb family BVB96_00235 ENOG4105F8V Hydrolase, tatD family BVB96_00240 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BVB96_00250 ENOG4105XFA sporulation peptidase YabG BVB96_00255 ENOG4105W42 Veg protein BVB96_00270 ENOG4105DFT pur operon repressor BVB96_00280 ENOG4105KME endoribonuclease L-psp BVB96_00295 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BVB96_00300 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BVB96_00310 ENOG4108JA2 transcriptioN-repair coupling factor BVB96_00315 ENOG4108M14 stage v sporulation protein t BVB96_00325 ENOG4108IY2 MazG family BVB96_00330 ENOG41082I2 s4 domain protein BVB96_00335 ENOG4105VYY sporulation protein yabp BVB96_00350 ENOG41060GV RNA binding s1 domain protein BVB96_00370 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BVB96_00375 ENOG4108UGV hypoxanthine phosphoribosyltransferase BVB96_00380 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BVB96_00395 ENOG4105C6T cysteine synthase BVB96_00400 ENOG4105CRQ synthase (Component I) BVB96_00405 ENOG4105DDQ anthranilate synthase BVB96_00410 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BVB96_00415 ENOG4105EEI dihydropteroate synthase BVB96_00420 ENOG4105KRF dihydroneopterin aldolase BVB96_00425 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BVB96_00435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BVB96_00465 ENOG4108Z0C Uvrb UvrC protein BVB96_00480 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BVB96_00490 ENOG4105CTP PilT protein domain protein BVB96_00510 ENOG4105D7W serine acetyltransferase BVB96_00525 ENOG4105C2N RNA methyltransferase TrmH family group 3 BVB96_00530 ENOG4105M0M Tetracycline resistance protein BVB96_00535 ENOG4105QIV RNA polymerase BVB96_00550 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BVB96_00575 ENOG4107Y49 methyltransferase BVB96_00585 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BVB96_00590 ENOG4105XPM ribosomal protein BVB96_00695 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BVB96_00720 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BVB96_00730 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BVB96_00740 ENOG41067V7 50S ribosomal protein L36 BVB96_00770 ENOG4108JJB ABC transporter BVB96_00775 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BVB96_00780 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BVB96_00805 ENOG4105D1F ATP-binding protein BVB96_00820 ENOG4108NMV polysaccharide deacetylase BVB96_00910 ENOG4105C8B TIGR00159 family BVB96_00915 ENOG4107U5W ybbr family BVB96_00930 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BVB96_00935 ENOG4108VQT Alpha beta hydrolase fold protein BVB96_00945 ENOG4105CMG Carbohydrate kinase BVB96_00955 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BVB96_00960 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BVB96_00995 ENOG4108UMI ABC transporter, permease BVB96_01000 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BVB96_01005 ENOG4105D01 (LipO)protein BVB96_01010 ENOG4105EE1 crotonyl-CoA reductase BVB96_01035 ENOG4105C2C drug resistance transporter, Bcr CflA BVB96_01050 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BVB96_01055 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVB96_01060 ENOG4105C3U ABC transporter BVB96_01065 ENOG4108JQ7 (ABC) transporter BVB96_01095 ENOG4108J59 Extracellular solute-binding protein, family 5 BVB96_01100 ENOG4108J59 Extracellular solute-binding protein, family 5 BVB96_01110 ENOG4105II7 pyrroline-5-carboxylate reductase BVB96_01120 ENOG4107XDY Nicotinamide Mononucleotide Transporter BVB96_01130 ENOG4105E0C molybdate abc transporter BVB96_01135 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BVB96_01140 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BVB96_01160 ENOG4105EGI Transcriptional regulator BVB96_01180 ENOG4105F6E Acyl-transferase BVB96_01205 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BVB96_01220 ENOG4108RE7 deoxyribonuclease BVB96_01225 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BVB96_01250 ENOG4105C5H ABC transporter BVB96_01265 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BVB96_01275 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVB96_01280 ENOG4105C3U ABC transporter BVB96_01285 ENOG4108JQ7 (ABC) transporter BVB96_01310 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BVB96_01315 ENOG4105ERH Fumarylacetoacetate hydrolase BVB96_01330 ENOG4108SC4 )-transporter BVB96_01340 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BVB96_01355 ENOG4107ZXI Rhomboid family BVB96_01365 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BVB96_01370 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BVB96_01380 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BVB96_01480 ENOG4105K8N protein family UPF0079, ATPase BVB96_01485 ENOG41072GX Peptidase M22 Glycoprotease BVB96_01490 ENOG410801F ribosomal-protein-alanine acetyltransferase BVB96_01495 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BVB96_01500 ENOG4105C5H ABC transporter BVB96_01515 ENOG4108TYN CAAX amino terminal protease family protein BVB96_01535 ENOG4105C7N Xanthine uracil vitamin C permease BVB96_01545 ENOG4105BZU Histidine kinase BVB96_01580 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BVB96_01625 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BVB96_01645 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_01670 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BVB96_01675 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BVB96_01680 ENOG4105C83 adenylosuccinate lyase BVB96_01690 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BVB96_01715 ENOG4108V3E phosphoribosylglycinamide formyltransferase BVB96_01725 ENOG4105C12 Phosphoribosylglycinamide synthetase BVB96_01750 ENOG4105C4R Atp-dependent dna helicase BVB96_01780 ENOG4108W2Y isochorismatase BVB96_01790 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BVB96_01795 ENOG4108UMI ABC transporter, permease BVB96_01800 ENOG4105D01 (LipO)protein BVB96_01820 ENOG4105D0U Arsenite-activated ATPase (ArsA) BVB96_01825 ENOG410834F Transcriptional regulator BVB96_01850 ENOG4105CBD Diacylglycerol kinase BVB96_01855 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BVB96_01860 ENOG4108JPW Aminotransferase BVB96_01870 ENOG4105C26 Dehydrogenase BVB96_01875 ENOG4105KPY Small multidrug resistance protein BVB96_01895 ENOG4105D9N nucleoside BVB96_01900 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BVB96_01915 ENOG4108W15 Protein of unknown function (DUF1456) BVB96_01930 ENOG4105DTQ mandelate racemase muconate lactonizing BVB96_01940 ENOG4105DFD Na H antiporter BVB96_01960 ENOG4105D3R alkyl hydroperoxide reductase BVB96_01965 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BVB96_01975 ENOG4107W7X Aldolase BVB96_01980 ENOG4105EHG Permease protein BVB96_01985 ENOG4105DQ5 transport system permease protein BVB96_01990 ENOG4108V5C ABC transporter BVB96_02020 ENOG4106UIA BVB96_02025 ENOG4106UIA BVB96_02055 ENOG4105BZU Histidine kinase BVB96_02075 ENOG410756H nucleotidyltransferase BVB96_02080 ENOG4105D2S major facilitator superfamily BVB96_02095 ENOG4105E5Q amino acid AbC transporter BVB96_02100 ENOG4105EAB amino acid AbC transporter BVB96_02115 ENOG4105C8Q Methyl-accepting chemotaxis BVB96_02120 ENOG4105C8Q Methyl-accepting chemotaxis BVB96_02130 ENOG4105CI1 PTS System BVB96_02160 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BVB96_02175 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BVB96_02190 ENOG4105C5H ABC transporter BVB96_02215 ENOG41062JF Transcriptional regulator BVB96_02235 ENOG4105DEU major facilitator superfamily BVB96_02265 ENOG4108N0M stress protein BVB96_02270 ENOG4106FN3 tellurium resistance protein BVB96_02275 ENOG4106FN3 tellurium resistance protein BVB96_02280 ENOG4107TS3 membrane protein, TerC BVB96_02285 ENOG4108TTB tellurium resistance protein BVB96_02305 ENOG4105KJF protein tyrosine phosphatase BVB96_02315 ENOG4107U9T Pfam:Ribonuclease_BN BVB96_02325 ENOG4105C59 p-type ATPase BVB96_02330 ENOG4108IPJ Membrane BVB96_02350 ENOG4107ZTW SNARE associated Golgi BVB96_02365 ENOG410606W general stress protein BVB96_02370 ENOG4105UPD Calcium Proton BVB96_02410 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BVB96_02415 ENOG4105VTR Integrase BVB96_02420 ENOG4108IMY Transcriptional regulator BVB96_02730 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BVB96_02740 ENOG4108JUB Transcriptional regulator BVB96_02750 ENOG4108IQI permease BVB96_02785 ENOG4105CSV Glutaminase BVB96_02800 ENOG4108A04 Beta-lactamase BVB96_02815 ENOG4105CKK Glycosyl transferase, family 2 BVB96_02825 ENOG4107QQG Dehydrogenase BVB96_02830 ENOG4105C3I Nad-dependent epimerase dehydratase BVB96_02845 ENOG4105F1A Pyruvate formate-lyase BVB96_02865 ENOG4105CI2 imidazolone-5-propionate hydrolase BVB96_02870 ENOG4105ECP epimerase BVB96_02900 ENOG41067AE Membrane-bound metal-dependent hydrolase BVB96_02905 ENOG4105CEN a g-specific adenine glycosylase BVB96_02910 ENOG4106BXE BVB96_02930 ENOG4105BZ1 (ABC) transporter BVB96_02935 ENOG4107NBY Membrane BVB96_02940 ENOG4105CBC glutamate synthase BVB96_02950 ENOG4108IUW ABC transporter BVB96_02970 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BVB96_02975 ENOG4105G5W regulator Fur family BVB96_03095 ENOG4108JQC penicillin-binding protein 1A BVB96_03100 ENOG4107ZQN disulfide bond BVB96_03110 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BVB96_03120 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BVB96_03125 ENOG4105BZU Histidine kinase BVB96_03135 ENOG4105CYN Serine protein kinase BVB96_03155 ENOG4105C94 Transporter BVB96_03170 ENOG4105DZ6 Band 7 protein BVB96_03180 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BVB96_03185 ENOG4108MRH transcriptional regulatory protein BVB96_03190 ENOG4105D4T Citrate transporter BVB96_03210 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BVB96_03215 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BVB96_03220 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BVB96_03225 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BVB96_03230 ENOG4105BZ7 extracellular solute-binding protein family 1 BVB96_03235 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BVB96_03240 ENOG4108STX response regulator BVB96_03245 ENOG4105US7 Histidine kinase BVB96_03270 ENOG4108MRH transcriptional regulatory protein BVB96_03280 ENOG4105C6K Malic enzyme BVB96_03290 ENOG4108UZ3 Transporter BVB96_03295 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVB96_03305 ENOG4105BZU Histidine kinase BVB96_03310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_03320 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BVB96_03325 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BVB96_03330 ENOG4108JB9 formate dehydrogenase BVB96_03350 ENOG4105CUB amino acid BVB96_03360 ENOG4105C59 p-type ATPase BVB96_03365 ENOG4105DAP Nicotinate phosphoribosyltransferase BVB96_03400 ENOG41073R8 VanW family BVB96_03405 ENOG4108KGH TRANSCRIPTIONal BVB96_03410 ENOG4105D9N nucleoside BVB96_03415 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BVB96_03420 ENOG4105C37 (CBS) domain BVB96_03425 ENOG4108IJ0 Aspartate ammonia-lyase BVB96_03430 ENOG4105DAA L-lactate BVB96_03445 ENOG4105DUX Transporter BVB96_03450 ENOG4108MES Periplasmic binding protein BVB96_03455 ENOG4105DQ5 transport system permease protein BVB96_03460 ENOG4108IHU transport system permease protein BVB96_03465 ENOG4105E0A ABC, transporter BVB96_03470 ENOG4105DMQ Methyltransferase BVB96_03480 ENOG4105EXW epimerase dehydratase BVB96_03490 ENOG4107T89 von Willebrand factor, type A BVB96_03495 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BVB96_03500 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BVB96_03515 ENOG4105BZU Histidine kinase BVB96_03520 ENOG4105D5Q Arginine ornithine antiporter BVB96_03525 ENOG4107414 GntR family transcriptional regulator BVB96_03530 ENOG4105C5Y PTS System BVB96_03535 ENOG4105CG3 alpha amylase, catalytic region BVB96_03550 ENOG4105E1K spore germination protein BVB96_03560 ENOG4105CRN Aminoglycoside phosphotransferase BVB96_03565 ENOG4105BZG amino acid carrier protein BVB96_03570 ENOG4105CDA abc transporter atp-binding protein BVB96_03575 ENOG4105CT1 (ABC) transporter BVB96_03580 ENOG4105EAD ABC transporter BVB96_03585 ENOG4105DRP amino acid AbC transporter BVB96_03590 ENOG4108IQI permease BVB96_03615 ENOG4105D29 Helix-turn-helix type 11 domain protein BVB96_03620 ENOG4105NAE bifunctional deaminase-reductase domain protein BVB96_03625 ENOG4105BZU Histidine kinase BVB96_03640 ENOG4105CHH sulfate transporter BVB96_03645 ENOG41068KF Universal stress protein BVB96_03655 ENOG4105DEF Extracellular solute-binding protein, family 5 BVB96_03665 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BVB96_03670 ENOG4108JQ7 (ABC) transporter BVB96_03680 ENOG4105CXY transporter BVB96_03685 ENOG41067TZ transcriptional regulator, MarR family BVB96_03695 ENOG4105ETE Transcriptional regulator (LacI family BVB96_03700 ENOG4108RVA ribokinase BVB96_03710 ENOG4105C2J ABC transporter BVB96_03715 ENOG4105CNN ABC, transporter BVB96_03720 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BVB96_03725 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BVB96_03785 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BVB96_03790 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BVB96_03795 ENOG41069ER domain protein BVB96_03800 ENOG4105VZ8 Transcriptional regulator BVB96_03805 ENOG4107D63 BVB96_03815 ENOG4105DUX Transporter BVB96_03835 ENOG4105C85 amino acid BVB96_03840 ENOG4105C7N Xanthine uracil vitamin C permease BVB96_03880 ENOG4105BZ9 Cytochrome C oxidase, subunit I BVB96_03885 ENOG4105E2S oxidase) subunit II BVB96_03890 ENOG4108IQI permease BVB96_03905 ENOG4106CAD Protein of unknown function (DUF3311) BVB96_03910 ENOG4105E1V na solute symporter BVB96_03925 ENOG4108NHD germination protein BVB96_03935 ENOG4105CE1 Ferrous iron transport protein b BVB96_03940 ENOG4105CE1 Ferrous iron transport protein b BVB96_03945 ENOG4105CE1 Ferrous iron transport protein b BVB96_03950 ENOG4105CVA phosphate BVB96_03955 ENOG4105C8U phosphate abc transporter BVB96_03960 ENOG4105E2Z phosphate ABC transporter (Permease BVB96_04085 ENOG41080XQ Signal transduction protein with cbs domains BVB96_04110 ENOG4105ETU transcriptional activator (TenA BVB96_04120 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BVB96_04130 ENOG4108VEU Thiamine monophosphate synthase BVB96_04135 ENOG41080HI glycine oxidase BVB96_04150 ENOG4105D06 uba thif-type nad fad binding protein BVB96_04155 ENOG4105DWF phosphomethylpyrimidine kinase BVB96_04210 ENOG4108INS Transcriptional regulator BVB96_04225 ENOG4105C7N Xanthine uracil vitamin C permease BVB96_04235 ENOG4108PXI ErfK YbiS YcfS YnhG BVB96_04255 ENOG4105C5Y PTS System BVB96_04310 ENOG4107Y03 Nitroreductase BVB96_04315 ENOG4105ED1 spovr family BVB96_04345 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BVB96_04350 ENOG4105XTG Pfam:DUF156 BVB96_04355 ENOG4105VFE sira family BVB96_04360 ENOG4107TPS domain protein BVB96_04365 ENOG4105VFE sira family BVB96_04380 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BVB96_04385 ENOG41087NI Sulfite exporter TauE/SafE BVB96_04395 ENOG4108KGH TRANSCRIPTIONal BVB96_04420 ENOG4105EMD TRANSCRIPTIONal BVB96_04425 ENOG4105VCP PTS System BVB96_04430 ENOG4105VZJ PTS System BVB96_04450 ENOG41069ER domain protein BVB96_04455 ENOG4107RBB ABC transporter, permease BVB96_04460 ENOG4105C19 ABC transporter BVB96_04490 ENOG4105WEF catalase BVB96_04525 ENOG4107T5V SNARE associated Golgi BVB96_04560 ENOG4105CUB amino acid BVB96_04565 ENOG4107RWR Sodium hydrogen exchanger BVB96_04575 ENOG4106KNT transcriptional regulator BVB96_04610 ENOG4108PCN EamA-like transporter family BVB96_04615 ENOG4108YXU transcriptional regulator AsnC family BVB96_04625 ENOG4105KPY Small multidrug resistance protein BVB96_04630 ENOG4105KPY Small multidrug resistance protein BVB96_04655 ENOG4105NF4 modulator of drug activity BVB96_04660 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BVB96_04665 ENOG4105E5W Transporter BVB96_04675 ENOG4107RKG DJ-1/PfpI family BVB96_04680 ENOG4105CH6 catalase BVB96_04690 ENOG4105D5Q Arginine ornithine antiporter BVB96_04695 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BVB96_04705 ENOG4105C26 Dehydrogenase BVB96_04725 ENOG4105BZ1 (ABC) transporter BVB96_04745 ENOG4105DRP amino acid AbC transporter BVB96_04750 ENOG4105CDA abc transporter atp-binding protein BVB96_04765 ENOG410839P BVB96_04800 ENOG4107FQX Alpha-acetolactate decarboxylase BVB96_04825 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BVB96_04835 ENOG4105D4P Coproporphyrinogen iii oxidase BVB96_04855 ENOG4105CHH sulfate transporter BVB96_04895 ENOG4106AKK s-layer domain-containing protein BVB96_04905 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BVB96_04910 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BVB96_04930 ENOG4105CGU Enoyl-CoA hydratase BVB96_04950 ENOG4105DER m42 family BVB96_04970 ENOG4105CTU Proline racemase BVB96_05020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVB96_05035 ENOG4108JQ7 (ABC) transporter BVB96_05045 ENOG4105PKS Excinuclease abc c subunit domain protein BVB96_05080 ENOG4105CSH Transporter BVB96_05090 ENOG4108MRH transcriptional regulatory protein BVB96_05140 ENOG4105CDU Replicative dna helicase BVB96_05190 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVB96_05245 ENOG4108IG5 Transcriptional regulator BVB96_05265 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BVB96_05285 ENOG4105CMT Dihydroxyacetone kinase BVB96_05295 ENOG4105CMT Dihydroxyacetone kinase BVB96_05300 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BVB96_05305 ENOG410847I Transcriptional regulator, BadM Rrf2 family BVB96_05340 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BVB96_05420 ENOG4105WN5 stage II sporulation protein BVB96_05430 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_05440 ENOG4108MJI response regulator BVB96_05445 ENOG4105BZU Histidine kinase BVB96_05450 ENOG4105BZU Histidine kinase BVB96_05510 ENOG4107VRP DNA repair exonuclease BVB96_05515 ENOG4106D4I domain protein BVB96_05520 ENOG4105D7V transposase BVB96_05535 ENOG4108IND Tetr family transcriptional regulator BVB96_05540 ENOG4105EQ0 Major Facilitator superfamily BVB96_05565 ENOG4108MUZ hydrolase BVB96_05585 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BVB96_05600 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BVB96_05620 ENOG4105EMN RNA polymerase sigma factor BVB96_05645 ENOG4105C57 major facilitator superfamily BVB96_05650 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVB96_05660 ENOG4105EEM helicase BVB96_05665 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BVB96_05690 ENOG4105K59 histidine triad (HIT) protein BVB96_05725 ENOG410905X membrane-flanked domain protein BVB96_05770 ENOG410905X membrane-flanked domain protein BVB96_05775 ENOG4105CKV Membrane BVB96_05780 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BVB96_05785 ENOG4105BZ4 penicillin-binding protein BVB96_05790 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BVB96_05800 ENOG4105C1Q protoporphyrinogen oxidase BVB96_05825 ENOG4105NA0 Transcriptional regulator BVB96_05840 ENOG4105ECB domain protein BVB96_05870 ENOG4106AXD BVB96_05875 ENOG4108RQ5 Beta-lactamase domain-containing protein BVB96_05880 ENOG4105DF9 Lipoate-protein, ligase BVB96_05895 ENOG4105CEY Amp-dependent synthetase and ligase BVB96_05925 ENOG4105CNA YD repeat protein BVB96_05970 ENOG4105ENX hydrolase BVB96_05980 ENOG4107RN3 metallophosphoesterase BVB96_05985 ENOG4107TVP HD domain protein BVB96_05995 ENOG4108AEY RNA polymerase sigma factor BVB96_06000 ENOG41086D8 Transcriptional regulator BVB96_06020 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_06045 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BVB96_06050 ENOG4105C8Q Methyl-accepting chemotaxis BVB96_06070 ENOG4105ZU5 s-layer protein BVB96_06075 ENOG4107QP3 malate synthase g BVB96_06090 ENOG4105VEQ Cold shock protein BVB96_06105 ENOG4105XVF Competence transcription factor BVB96_06120 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BVB96_06125 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BVB96_06170 ENOG4105ERH Fumarylacetoacetate hydrolase BVB96_06195 ENOG4105CAQ asparagine synthetase BVB96_06200 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BVB96_06205 ENOG4105CH6 catalase BVB96_06210 ENOG4105BZU Histidine kinase BVB96_06235 ENOG4105QNR S1 RNA binding domain protein BVB96_06245 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BVB96_06255 ENOG4107AYK membrAne BVB96_06260 ENOG41073B9 BVB96_06270 ENOG4108KP7 hydrolase BVB96_06280 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BVB96_06310 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BVB96_06315 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BVB96_06330 ENOG4105C31 Tryptophanyl-tRNA synthetase BVB96_06350 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BVB96_06355 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVB96_06365 ENOG4108JQ7 (ABC) transporter BVB96_06370 ENOG4105UQX Mate efflux family protein BVB96_06390 ENOG4108ZCF integral membrane protein BVB96_06400 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BVB96_06410 ENOG4105DPN Oligoendopeptidase f BVB96_06425 ENOG4108Z18 K06886 hemoglobin BVB96_06430 ENOG4105MIX Adenylate cyclase BVB96_06445 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BVB96_06450 ENOG4105EMS pseudouridine synthase BVB96_06470 ENOG4105K64 Glycosyl transferase, family 2 BVB96_06510 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BVB96_06515 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BVB96_06525 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BVB96_06575 ENOG4108WVJ 2'-5' rna ligase BVB96_06600 ENOG4105CK7 Sodium proline symporter BVB96_06610 ENOG4105CRQ synthase (Component I) BVB96_06615 ENOG4105DDQ anthranilate synthase BVB96_06710 ENOG4105C7S Dehydrogenase BVB96_06720 ENOG4105VZ8 Transcriptional regulator BVB96_06780 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BVB96_06795 ENOG4105DZ1 carboxypeptidase BVB96_06800 ENOG4105VFR signal peptidase BVB96_06835 ENOG4105C26 Dehydrogenase BVB96_06840 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BVB96_06845 ENOG4105F38 ABC transporter, permease BVB96_06850 ENOG4105D38 putrescine abc transporter BVB96_06855 ENOG4107RUE extracellular solute-binding protein family 1 BVB96_06865 ENOG4105EYF MMPL domain protein BVB96_06875 ENOG4108YBP pseudouridine synthase BVB96_06885 ENOG4105K4I Scp-like extracellular BVB96_06890 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BVB96_06895 ENOG4105CQB FAD linked oxidase domain protein BVB96_06910 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_06915 ENOG4105BZU Histidine kinase BVB96_06920 ENOG4105JXH GntR family transcriptional regulator BVB96_06940 ENOG4106A3R peptidase BVB96_06950 ENOG4108QTI )-transporter BVB96_06955 ENOG4107TS3 membrane protein, TerC BVB96_06965 ENOG410681C small acid-soluble spore protein BVB96_06970 ENOG4108Z7G MaoC domain protein dehydratase BVB96_06990 ENOG4105CHR reductase BVB96_07000 ENOG4105MWK D-amino acid dehydrogenase, small subunit BVB96_07025 ENOG4105C4Y ABC transporter BVB96_07040 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BVB96_07055 ENOG4105E98 transcriptional regulator DeoR family BVB96_07075 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BVB96_07090 ENOG4105PXI polysaccharide deacetylase BVB96_07100 ENOG4105BZU Histidine kinase BVB96_07105 ENOG41090MY MarR family Transcriptional regulator BVB96_07115 ENOG4106DF1 BVB96_07125 ENOG4105BZU Histidine kinase BVB96_07135 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BVB96_07140 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BVB96_07185 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BVB96_07190 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BVB96_07200 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BVB96_07205 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BVB96_07210 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BVB96_07215 ENOG4105CZV ABC transporter BVB96_07225 ENOG4105CJ1 ABC, transporter BVB96_07265 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BVB96_07270 ENOG4105EA8 2-Nitropropane dioxygenase BVB96_07275 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BVB96_07285 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BVB96_07310 ENOG4105NQC Flavodoxin BVB96_07350 ENOG4107QMU Mate efflux family protein BVB96_07355 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BVB96_07390 ENOG41063Y9 BVB96_07395 ENOG4105KBJ sporulation protein ytfj BVB96_07425 ENOG4105CM2 brancheD-chain amino acid aminotransferase BVB96_07430 ENOG4105C7K acetolactate synthase BVB96_07435 ENOG4108ZP8 Acetolactate synthase small subunit BVB96_07440 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BVB96_07450 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BVB96_07475 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BVB96_07510 ENOG4107RVV histidinol phosphate phosphatase, hisj family BVB96_07525 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BVB96_07530 ENOG4105E0M Sulfatase BVB96_07540 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BVB96_07560 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BVB96_07565 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BVB96_07575 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BVB96_07580 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BVB96_07585 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BVB96_07590 ENOG4105C8J )-transporter BVB96_07610 ENOG4105DFD Na H antiporter BVB96_07630 ENOG4105ENE Histidine kinase BVB96_07635 ENOG4105WH1 Two component transcriptional regulator luxr family BVB96_07655 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BVB96_07680 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BVB96_07700 ENOG4105CJ3 phosphate transporter BVB96_07705 ENOG4107GRR phosphate transport regulator BVB96_07710 ENOG4105BZ4 penicillin-binding protein BVB96_07730 ENOG4105I3N Conserved Protein BVB96_07745 ENOG4105BZU Histidine kinase BVB96_07790 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BVB96_07795 ENOG4105DZ1 carboxypeptidase BVB96_07800 ENOG4108JIC nucleoside recognition domain protein BVB96_07810 ENOG4105FE9 pseudouridine synthase BVB96_07820 ENOG4107TWT Cytochrome c biogenesis protein BVB96_07825 ENOG4105CRE cytochrome C BVB96_07830 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_07835 ENOG4105BZU Histidine kinase BVB96_07840 ENOG4108WBT adenosyltransferase BVB96_07855 ENOG4108SAX Membrane BVB96_07865 ENOG4105T7X BVB96_07870 ENOG4105C9U ATP-dependent DNA helicase RecQ BVB96_07875 ENOG4105I7S Abortive infection protein BVB96_07890 ENOG4107X2D transcriptional regulator, merr family BVB96_07895 ENOG4108S6Z Negative regulator of genetic competence BVB96_07920 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BVB96_07925 ENOG4105HDK L-asparaginase BVB96_07960 ENOG4105S2F BVB96_07965 ENOG41065D1 BVB96_07995 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BVB96_08010 ENOG4105XXQ heptaprenyl diphosphate synthase component I BVB96_08020 ENOG4105EAH synthase BVB96_08040 ENOG4105CIH Imidazole acetol-phosphate transaminase BVB96_08045 ENOG41068YB TPR repeat-containing protein BVB96_08060 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BVB96_08065 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BVB96_08070 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BVB96_08105 ENOG4108JYZ YitT family BVB96_08115 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BVB96_08130 ENOG4105FJR Lmbe family BVB96_08135 ENOG4105CPK Glycosyl transferase (Group 1 BVB96_08180 ENOG4105YAC BVB96_08200 ENOG4105CSM endonuclease III BVB96_08210 ENOG4105BZ4 penicillin-binding protein BVB96_08275 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BVB96_08285 ENOG4105DVT helicase BVB96_08290 ENOG4105CTD carboxy-peptidase BVB96_08305 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BVB96_08315 ENOG4105C2W permease BVB96_08320 ENOG4105DHF Membrane BVB96_08330 ENOG410890F Dynamin family BVB96_08340 ENOG4108W0I acetyltransferase BVB96_08350 ENOG4105KHC sulfurtransferase BVB96_08455 ENOG4108SZE gCN5-related N-acetyltransferase BVB96_08475 ENOG41081VK Ribonuclease BVB96_08540 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BVB96_08555 ENOG4107RWR Sodium hydrogen exchanger BVB96_08560 ENOG4105CN5 Metallo-Beta-Lactamase BVB96_08565 ENOG4108Z5V transcriptional regulator, merr family BVB96_08575 ENOG4105H67 Protein of unknown function (DUF421) BVB96_08580 ENOG41080C8 DUF218 domain BVB96_08635 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BVB96_08645 ENOG4107R0U MotA TolQ exbB proton channel BVB96_08650 ENOG4105ER2 Ompa motb domain protein BVB96_08655 ENOG4107YTP response regulator receiver protein BVB96_08660 ENOG4105CBS Chea signal transduction histidine kinase BVB96_08665 ENOG4105CBS Chea signal transduction histidine kinase BVB96_08670 ENOG4105DD5 Flagellar motor switch protein BVB96_08685 ENOG4105BZU Histidine kinase BVB96_08705 ENOG4105E1Q flagellar hook-associated protein BVB96_08735 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BVB96_08740 ENOG4108ZC9 flagellar basal-body rod protein flgc BVB96_08745 ENOG41075Z6 flagellar hook-basal body complex protein fliE BVB96_08755 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BVB96_08790 ENOG4105BZE flagellar hook protein, FlgE BVB96_08810 ENOG4107R88 Chemotaxis protein (CheV) BVB96_08820 ENOG4105K64 Glycosyl transferase, family 2 BVB96_08880 ENOG4105I03 Flagellin BVB96_08885 ENOG4105E4C Lytic transglycosylase catalytic BVB96_08895 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BVB96_08905 ENOG4105DD5 Flagellar motor switch protein BVB96_08915 ENOG4105CN7 Flagellar biosynthetic protein FliP BVB96_08920 ENOG4105VS8 Flagellar biosynthetic protein fliq BVB96_08930 ENOG4105D00 flagellar biosynthetic protein flhB BVB96_08935 ENOG4105D7B Flagellar biosynthesis protein flha BVB96_08940 ENOG4105FZW flagellar biosynthesis regulator FlhF BVB96_08945 ENOG4105KTQ flagellar basal-body rod protein BVB96_08950 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BVB96_08975 ENOG4108RZE Tetr family transcriptional regulator BVB96_08995 ENOG4105KAC Antibiotic biosynthesis monooxygenase BVB96_09025 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BVB96_09030 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BVB96_09035 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BVB96_09040 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BVB96_09080 ENOG4105CVJ phosphoglycerate mutase BVB96_09110 ENOG4105CAQ asparagine synthetase BVB96_09130 ENOG4105PGM cation diffusion facilitator family transporter BVB96_09140 ENOG4105DRR Transcriptional regulator, GntR family BVB96_09145 ENOG4108UZ3 Transporter BVB96_09150 ENOG4105CKI cobalamin synthesis protein BVB96_09160 ENOG4108PJD permease BVB96_09175 ENOG4105DFD Na H antiporter BVB96_09180 ENOG4105C9Q fumarate hydratase class II BVB96_09210 ENOG4105EC3 peptidase S51, dipeptidase E BVB96_09230 ENOG4107QIV Cytochrome c biogenesis protein BVB96_09265 ENOG4106BRA Membrane BVB96_09305 ENOG4105CJ1 ABC, transporter BVB96_09325 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BVB96_09335 ENOG4108IJ0 Aspartate ammonia-lyase BVB96_09340 ENOG4105C6K Malic enzyme BVB96_09415 ENOG4105FVX BVB96_09455 ENOG4105CSR polyphosphate kinase 2 BVB96_09465 ENOG4105DXI Major Facilitator superfamily BVB96_09480 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BVB96_09495 ENOG4105C6T cysteine synthase BVB96_09515 ENOG4105C8J )-transporter BVB96_09525 ENOG4105X5K response regulator receiver protein BVB96_09530 ENOG4105H67 Protein of unknown function (DUF421) BVB96_09550 ENOG4106KE4 Dehydrogenase BVB96_09570 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BVB96_09575 ENOG4105CHR reductase BVB96_09580 ENOG4105CM2 brancheD-chain amino acid aminotransferase BVB96_09585 ENOG4105C7K acetolactate synthase BVB96_09590 ENOG4108ZP8 Acetolactate synthase small subunit BVB96_09595 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BVB96_09605 ENOG4105C7B Threonine dehydratase BVB96_09640 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BVB96_09650 ENOG4105DY9 regulatoR BVB96_09655 ENOG4105CYC Transferase BVB96_09675 ENOG4105F6J Alpha beta hydrolase fold BVB96_09685 ENOG4108J59 Extracellular solute-binding protein, family 5 BVB96_09720 ENOG41068WN BVB96_09740 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BVB96_09745 ENOG4105C72 UPF0176 protein BVB96_09755 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BVB96_09785 ENOG4107RHR regulatoR BVB96_09795 ENOG4105D9N nucleoside BVB96_09800 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BVB96_09835 ENOG4107RAQ aminopeptidase BVB96_09840 ENOG4107STQ Multicopper oxidase BVB96_09885 ENOG4108T5E Copper resistance protein BVB96_09890 ENOG4105KTB nuclear export factor GLE1 BVB96_09900 ENOG4107RT3 EamA-like transporter family BVB96_09905 ENOG4105GZI Transcriptional regulator BVB96_09910 ENOG4108Z40 Transcriptional regulator BVB96_09915 ENOG4107ZXU DSBA oxidoreductase BVB96_09920 ENOG4108TVJ Nitroreductase BVB96_09930 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BVB96_09935 ENOG4106F5Q Membrane BVB96_09940 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BVB96_09950 ENOG4105CKI cobalamin synthesis protein BVB96_09970 ENOG4108Z7G MaoC domain protein dehydratase BVB96_09975 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BVB96_09990 ENOG4105C0Z ABC transporter BVB96_09995 ENOG4108IV0 ABC, transporter BVB96_10000 ENOG4105C32 Amino acid ABC transporter (Permease) BVB96_10010 ENOG4105SKE transcriptional Regulator LysR family BVB96_10020 ENOG4105MDS 4-oxalocrotonate tautomerase BVB96_10030 ENOG4105YGB Transcriptional regulator BVB96_10040 ENOG4105C4M (Ubiquinol oxidase) subunit I BVB96_10045 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BVB96_10050 ENOG4108JJ9 ABC, transporter BVB96_10055 ENOG4108JJ8 (ABC) transporter BVB96_10100 ENOG4105BZ1 (ABC) transporter BVB96_10105 ENOG4105BZ1 (ABC) transporter BVB96_10110 ENOG4105EFI regulatoR BVB96_10135 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BVB96_10140 ENOG4108ZJ4 polysaccharide deacetylase BVB96_10170 ENOG4105D6E homoserine dehydrogenase BVB96_10195 ENOG4108KGH TRANSCRIPTIONal BVB96_10205 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_10210 ENOG4105BZU Histidine kinase BVB96_10215 ENOG4107VMI polysaccharide deacetylase BVB96_10225 ENOG4105KT7 mgtC SapB transporter BVB96_10230 ENOG4105VRR gCN5-related N-acetyltransferase BVB96_10240 ENOG4105DUU IucA IucC family protein BVB96_10245 ENOG4105CEY Amp-dependent synthetase and ligase BVB96_10260 ENOG4108WBH protein TIM barrel BVB96_10265 ENOG4105YWU small acid-soluble spore protein BVB96_10275 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BVB96_10330 ENOG4105KRN Transcriptional regulator, abrb family BVB96_10340 ENOG4105YVS arsR family transcriptional regulator BVB96_10345 ENOG4107SET aldo keto reductase BVB96_10375 ENOG4105C8Q Methyl-accepting chemotaxis BVB96_10390 ENOG4108K88 Membrane BVB96_10395 ENOG4108WPJ Ferritin-like domain BVB96_10410 ENOG4105DEN Luciferase family BVB96_10430 ENOG4107QM2 Aldo Keto reductase BVB96_10435 ENOG4105CKI cobalamin synthesis protein BVB96_10515 ENOG4105DSE periplasmic solute binding protein BVB96_10525 ENOG4105K4T epimerase BVB96_10535 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BVB96_10560 ENOG4105CVJ phosphoglycerate mutase BVB96_10580 ENOG4107T5V SNARE associated Golgi BVB96_10595 ENOG4108PJD permease BVB96_10605 ENOG4108S4H thioesterase Superfamily protein BVB96_10615 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BVB96_10635 ENOG4105SXS Protein of unknown function (DUF456) BVB96_10640 ENOG4105C37 (CBS) domain BVB96_10660 ENOG4108Z7R Chaperone CsaA BVB96_10680 ENOG4108ZRV stage ii sporulation protein p BVB96_10690 ENOG4108VXD carboxy-peptidase BVB96_10700 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BVB96_10725 ENOG4108X4Q Hydrolase BVB96_10735 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BVB96_10740 ENOG4107RBS Methyltransferase BVB96_10755 ENOG41087PP glycosyltransferase MGT family BVB96_10760 ENOG4108JYZ YitT family BVB96_10765 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVB96_10795 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BVB96_10855 ENOG4105KBJ sporulation protein ytfj BVB96_10880 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BVB96_10900 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BVB96_10905 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_10915 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BVB96_10920 ENOG4105EMN RNA polymerase sigma factor BVB96_10945 ENOG4108V06 Glutathione peroxidase BVB96_10960 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BVB96_10980 ENOG4108IUE nitrate reductase beta subunit BVB96_10985 ENOG4105R3A Nitrate reductase BVB96_11010 ENOG4107V6Q Cyclic nucleotide-binding domain BVB96_11015 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BVB96_11020 ENOG4105D06 uba thif-type nad fad binding protein BVB96_11025 ENOG4105CVM Molybdenum cofactor synthesis domain protein BVB96_11030 ENOG4108ZAF Molybdopterin BVB96_11060 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BVB96_11065 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BVB96_11070 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BVB96_11075 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BVB96_11080 ENOG4108IFG nitrite reductase, (NAD(P)H) BVB96_11085 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BVB96_11120 ENOG4105MCT stage V sporulation protein S BVB96_11140 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BVB96_11160 ENOG4105C5H ABC transporter BVB96_11175 ENOG4108UUM single-stranded DNA-binding protein BVB96_11205 ENOG4107YX5 Pfam:DUF548 BVB96_11210 ENOG4105C75 arginyL-tRNA synthetase BVB96_11240 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BVB96_11260 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BVB96_11265 ENOG4105C5S asparaginyl-tRNA synthetase BVB96_11285 ENOG4105EC2 ftsk spoIIIe BVB96_11385 ENOG4105BZW Glycerate kinase BVB96_11390 ENOG4107QPK )-transporter BVB96_11395 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_11400 ENOG41062D9 Histidine kinase BVB96_11415 ENOG4105C8J )-transporter BVB96_11435 ENOG4107XGZ Hydrolase BVB96_11440 ENOG4105CY2 Citrate transporter BVB96_11445 ENOG4105C0A alcohol dehydrogenase BVB96_11460 ENOG4105KD7 acetyltransferase BVB96_11490 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BVB96_11510 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BVB96_11525 ENOG4107RVG penicillin-binding protein BVB96_11530 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BVB96_11535 ENOG4105E9Q Acyl-transferase BVB96_11540 ENOG4108UT2 hemolysin iii BVB96_11550 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BVB96_11565 ENOG4108RCR degv family BVB96_11570 ENOG4105E8R UPF0173 metal-dependent hydrolase BVB96_11575 ENOG4108KF3 Electron transport protein SCO1 SenC BVB96_11580 ENOG4107Y70 Heat shock protein BVB96_11585 ENOG4105CAQ asparagine synthetase BVB96_11605 ENOG4108MES Periplasmic binding protein BVB96_11610 ENOG4105F0I Aminotransferase BVB96_11645 ENOG4105D8X mechanosensitive ion channel BVB96_11650 ENOG4105BZU Histidine kinase BVB96_11655 ENOG4105WH1 Two component transcriptional regulator luxr family BVB96_11665 ENOG4106KNT transcriptional regulator BVB96_11700 ENOG4105CMG Carbohydrate kinase BVB96_11705 ENOG4105CMG Carbohydrate kinase BVB96_11735 ENOG4108IJ8 ABC transporter BVB96_11740 ENOG4105E90 ABC transporter BVB96_11775 ENOG4105C37 (CBS) domain BVB96_11805 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BVB96_11820 ENOG4107S4Y M20 DapE family protein YgeY BVB96_11825 ENOG4108TSC N-acetyltransferase BVB96_11830 ENOG4108JUB Transcriptional regulator BVB96_11840 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BVB96_11880 ENOG4108N23 SpoOM-related protein BVB96_11885 ENOG410841Q phosphoesterase PA-phosphatase related protein BVB96_11895 ENOG4105SZ6 Thioredoxin BVB96_11910 ENOG4108IBT Inherit from COG: transposase BVB96_12035 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BVB96_12075 ENOG4105BZ4 penicillin-binding protein BVB96_12080 ENOG4105CZM Major Facilitator BVB96_12085 ENOG4105W8X HesB YadR YfhF-family protein BVB96_12095 ENOG4105DXD 2-methylcitrate dehydratase BVB96_12100 ENOG4105CR4 methylisocitrate lyase BVB96_12105 ENOG4105C1G acyl-Coa dehydrogenase BVB96_12110 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BVB96_12120 ENOG4105N14 lysine exporter protein LysE YggA BVB96_12125 ENOG4105E39 Enoyl-CoA hydratase BVB96_12140 ENOG4107RFY SbcCD D subunit BVB96_12145 ENOG4105EYH Exonuclease BVB96_12180 ENOG4105FCD Major Facilitator BVB96_12190 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BVB96_12195 ENOG4105E4F Isochorismate synthase BVB96_12200 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BVB96_12205 ENOG4105WQI isochorismatase BVB96_12215 ENOG4105WQT MbtH domain protein BVB96_12220 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVB96_12235 ENOG4105K70 DNA-binding protein BVB96_12275 ENOG4105FE9 pseudouridine synthase BVB96_12280 ENOG4105C22 threonyL-tRNA synthetase BVB96_12285 ENOG4105C19 ABC transporter BVB96_12305 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BVB96_12335 ENOG4108D32 Methyltransferase BVB96_12365 ENOG41081I9 integral membrane protein BVB96_12380 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BVB96_12390 ENOG4105EYF MMPL domain protein BVB96_12415 ENOG4105WCN acetyltransferase BVB96_12445 ENOG4105C1Q protoporphyrinogen oxidase BVB96_12455 ENOG41068WN BVB96_12465 ENOG4105VEQ Cold shock protein BVB96_12485 ENOG410667J hydrolase BVB96_12530 ENOG4107V2S Transcriptional regulator BVB96_12535 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BVB96_12550 ENOG4105DND Transcriptional regulator BVB96_12555 ENOG4108RPX mosc domain containing protein BVB96_12570 ENOG4105BZ1 (ABC) transporter BVB96_12575 ENOG4105BZ1 (ABC) transporter BVB96_12595 ENOG4108JCI Transcriptional regulator BVB96_12625 ENOG4108KPJ rna polymerase sigma factor BVB96_12655 ENOG4105F32 YngK protein BVB96_12685 ENOG4105RD7 BadF BadG BcrA BcrD BVB96_12695 ENOG4107STF Involved in phosphonate degradation (By similarity) BVB96_12715 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BVB96_12730 ENOG4105C1J atp-dependent rna helicase BVB96_12745 ENOG4108RZE Tetr family transcriptional regulator BVB96_12765 ENOG41088CC tellurite resistance protein tehB BVB96_12775 ENOG4108I0C methyltransferase BVB96_12780 ENOG4107RA9 decarboxylase BVB96_12785 ENOG41090HR transcriptional regulator BVB96_12835 ENOG4105CIN aminoacyl-histidine dipeptidase BVB96_12865 ENOG4107RF6 penicillin-binding protein BVB96_12870 ENOG4107RF6 penicillin-binding protein BVB96_12885 ENOG4105ETE Transcriptional regulator (LacI family BVB96_12895 ENOG4105CK5 oxidoreductase BVB96_12920 ENOG4105D2N Aldolase BVB96_12940 ENOG4105CGH 5'-nucleotidase BVB96_12955 ENOG4105VZ8 Transcriptional regulator BVB96_12975 ENOG4108VXD carboxy-peptidase BVB96_12995 ENOG41067SE Tetr family transcriptional regulator BVB96_13000 ENOG4105C5H ABC transporter BVB96_13010 ENOG4105BZU Histidine kinase BVB96_13025 ENOG4106ANW SMI1_KNR4 BVB96_13035 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BVB96_13050 ENOG4105CJ1 ABC, transporter BVB96_13060 ENOG4107Z3H Transcriptional regulator, TetR family BVB96_13080 ENOG4105C1G acyl-Coa dehydrogenase BVB96_13085 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BVB96_13090 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BVB96_13095 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BVB96_13100 ENOG4105E39 Enoyl-CoA hydratase BVB96_13105 ENOG4107QX3 carboxylase BVB96_13110 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BVB96_13120 ENOG4105WCN acetyltransferase BVB96_13125 ENOG4105DBI uridine monophosphokinase BVB96_13140 ENOG4105DZ1 carboxypeptidase BVB96_13155 ENOG4105T9C HD domain BVB96_13165 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BVB96_13205 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BVB96_13205 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BVB96_13220 ENOG4105FQP Beta-lactamase BVB96_13230 ENOG4107Y80 Major Facilitator superfamily BVB96_13250 ENOG4105CUV Homoserine Kinase BVB96_13285 ENOG4105CPQ Dehydrogenase BVB96_13400 ENOG4105ETU transcriptional activator (TenA BVB96_13535 ENOG410667J hydrolase BVB96_13545 ENOG4105BZU Histidine kinase BVB96_13550 ENOG4107RF6 penicillin-binding protein BVB96_13570 ENOG4108JJB ABC transporter BVB96_13585 ENOG4108HGU Histidine kinase BVB96_13600 ENOG4105CB2 alcohol dehydrogenase BVB96_13605 ENOG4105CJN penicillin-binding protein BVB96_13615 ENOG4105FQP Beta-lactamase BVB96_13650 ENOG4108V4B ThiJ pfpI BVB96_13685 ENOG4107Y80 Major Facilitator superfamily BVB96_13705 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BVB96_13725 ENOG4107Y9U Membrane BVB96_13730 ENOG4107Y9U Membrane BVB96_13770 ENOG4105FCD Major Facilitator BVB96_13785 ENOG4105E09 nadh pyrophosphatase BVB96_13790 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BVB96_13795 ENOG4108Z4K mutator MutT protein BVB96_13830 ENOG4108XI2 Domain of unknown function (DUF1963) BVB96_13860 ENOG4105KWG Pfam:DUF1696 BVB96_13895 ENOG4105PKS Excinuclease abc c subunit domain protein BVB96_13940 ENOG4107VFR oxidoreductase BVB96_13965 ENOG4105PAD Hydrolase BVB96_13985 ENOG4105DY8 decarboxylase BVB96_14000 ENOG4108IUM Glycogen debranching enzyme BVB96_14025 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BVB96_14035 ENOG4105FDR Membrane BVB96_14070 ENOG4108V3A UPF0421 protein BVB96_14090 ENOG4105MSI germination protein ypeb BVB96_14110 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BVB96_14115 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BVB96_14120 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BVB96_14125 ENOG4107Z3H Transcriptional regulator, TetR family BVB96_14160 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BVB96_14180 ENOG4105E98 transcriptional regulator DeoR family BVB96_14205 ENOG41062ES Transcriptional regulator BVB96_14230 ENOG4107QKR Dehydrogenase BVB96_14240 ENOG4107RUY (E1 component), alpha subunit BVB96_14250 ENOG4105E1F short-chain dehydrogenase reductase BVB96_14255 ENOG4105RHY Pfam:UPF0157 BVB96_14290 ENOG4107SQ8 Glycine betaine BVB96_14295 ENOG4108IJ7 Glycine betaine BVB96_14320 ENOG4105E66 phosphoriboisomerase A BVB96_14325 ENOG41082BV acetyltransferase BVB96_14330 ENOG4108M1A Chitin-binding protein BVB96_14375 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BVB96_14405 ENOG4108Z7F N-acetyltransferase BVB96_14425 ENOG4105EEM helicase BVB96_14445 ENOG4105C9U ATP-dependent DNA helicase RecQ BVB96_14495 ENOG4108M1A Chitin-binding protein BVB96_14510 ENOG4105BZG amino acid carrier protein BVB96_14515 ENOG4105C26 Dehydrogenase BVB96_14520 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVB96_14525 ENOG4105CTU Proline racemase BVB96_14530 ENOG4105CTU Proline racemase BVB96_14535 ENOG41080HI glycine oxidase BVB96_14575 ENOG4107T5V SNARE associated Golgi BVB96_14590 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BVB96_14595 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BVB96_14610 ENOG4105DTQ mandelate racemase muconate lactonizing BVB96_14660 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BVB96_14665 ENOG4105BZU Histidine kinase BVB96_14670 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_14705 ENOG4105DPN Oligoendopeptidase f BVB96_14720 ENOG4105EPR degv family BVB96_14765 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BVB96_14770 ENOG4106K7D Major facilitator family transporter BVB96_14790 ENOG4107BMA Transglycosylase associated protein BVB96_14805 ENOG41089UC methyltransferase, type 11 BVB96_14850 ENOG4105CHM Aminotransferase BVB96_14880 ENOG4105DVE abc transporter atp-binding protein BVB96_14930 ENOG4105C02 permease BVB96_14945 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BVB96_14950 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVB96_14955 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BVB96_14980 ENOG4105E09 nadh pyrophosphatase BVB96_15000 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BVB96_15055 ENOG4107VC0 DNA alkylation repair enzyme BVB96_15070 ENOG4107VMI polysaccharide deacetylase BVB96_15080 ENOG4108ZCF integral membrane protein BVB96_15085 ENOG4105E0M Sulfatase BVB96_15095 ENOG4105C5H ABC transporter BVB96_15110 ENOG41082JN Transcriptional regulator BVB96_15130 ENOG4105CIH Imidazole acetol-phosphate transaminase BVB96_15135 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BVB96_15145 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BVB96_15195 ENOG41069ER domain protein BVB96_15210 ENOG4105EMN RNA polymerase sigma factor BVB96_15235 ENOG4105D4B ABC, transporter BVB96_15245 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BVB96_15255 ENOG4105DKT Transcriptional regulator BVB96_15260 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BVB96_15270 ENOG41061GT Aldolase BVB96_15290 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BVB96_15320 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BVB96_15325 ENOG4105II7 pyrroline-5-carboxylate reductase BVB96_15335 ENOG4107258 Transcriptional regulator BVB96_15345 ENOG4105E0Y RtcB Protein BVB96_15350 ENOG4105ECK Fatty Acid Desaturase BVB96_15355 ENOG4105G6Z alkaline phosphatase BVB96_15365 ENOG4105VMP Transcriptional regulator BVB96_15380 ENOG41090T1 Membrane BVB96_15390 ENOG4108WCX response regulator BVB96_15400 ENOG41068WN BVB96_15425 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BVB96_15450 ENOG4105CKK Glycosyl transferase, family 2 BVB96_15475 ENOG4105CKK Glycosyl transferase, family 2 BVB96_15485 ENOG4105C8Y Acetylornithine aminotransferase BVB96_15530 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BVB96_15540 ENOG4108TVJ Nitroreductase BVB96_15545 ENOG4105FS7 Transcriptional regulator BVB96_15585 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BVB96_15600 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BVB96_15630 ENOG4108XET gCN5-related N-acetyltransferase BVB96_15710 ENOG410635A Membrane BVB96_15715 ENOG4105KNA -acetyltransferase BVB96_15720 ENOG4108IQI permease BVB96_15730 ENOG4105F1N DNA alkylation repair BVB96_15770 ENOG4107RF6 penicillin-binding protein BVB96_15780 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BVB96_15815 ENOG4105P4J Allophanate hydrolase, subunit 1 BVB96_15820 ENOG4107258 Transcriptional regulator BVB96_15830 ENOG4106N3A copper homeostasis protein cutc BVB96_15840 ENOG4108ZRV stage ii sporulation protein p BVB96_15845 ENOG4108ZHR arsR family transcriptional regulator BVB96_15855 ENOG4105FDT acyl-CoA dehydrogenase BVB96_15875 ENOG4105DWD nucleoside recognition domain protein BVB96_15905 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BVB96_15980 ENOG4105E2A Dehydrogenase BVB96_15995 ENOG4108IJ0 Aspartate ammonia-lyase BVB96_16000 ENOG4105HDK L-asparaginase BVB96_16005 ENOG4108IMY Transcriptional regulator BVB96_16015 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BVB96_16020 ENOG4105CUB amino acid BVB96_16030 ENOG4105II7 pyrroline-5-carboxylate reductase BVB96_16040 ENOG4105C6K Malic enzyme BVB96_16055 ENOG4108Q8B Spore germination protein BVB96_16085 ENOG4105CSV Glutaminase BVB96_16120 ENOG4105CGH 5'-nucleotidase BVB96_16125 ENOG4105CH6 catalase BVB96_16135 ENOG4105CHJ isochorismatase hydrolase BVB96_16165 ENOG41090MY MarR family Transcriptional regulator BVB96_16205 ENOG4108606 TspO/MBR family BVB96_16210 ENOG4105CVP deoxyribo-dipyrimidine photolyase BVB96_16225 ENOG4108TWJ NADH dehydrogenase subunit 5 BVB96_16230 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BVB96_16245 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BVB96_16250 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BVB96_16260 ENOG4105DSE periplasmic solute binding protein BVB96_16265 ENOG4105CC5 ABC transporter BVB96_16270 ENOG4105DIK (ABC) transporter BVB96_16300 ENOG4105D6J arsenicaL-resistance protein BVB96_16305 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_16310 ENOG41085FC arsR family transcriptional regulator BVB96_16325 ENOG4105F7F Chaperone BVB96_16335 ENOG4105CHR reductase BVB96_16340 ENOG4108YXU transcriptional regulator AsnC family BVB96_16420 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BVB96_16430 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVB96_16445 ENOG4105IIP Membrane BVB96_16460 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_16465 ENOG41062D9 Histidine kinase BVB96_16490 ENOG4105K6H D-cysteine desulfhydrase BVB96_16520 ENOG4105VZ8 Transcriptional regulator BVB96_16535 ENOG4108NNI Beta-lactamase domain-containing protein BVB96_16540 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BVB96_16550 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BVB96_16555 ENOG4105JQZ Methyltransferase BVB96_16570 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BVB96_16575 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BVB96_16595 ENOG4105BZU Histidine kinase BVB96_16610 ENOG4108U05 Transcriptional regulator BVB96_16615 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BVB96_16620 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BVB96_16630 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BVB96_16635 ENOG4105DJB Major Facilitator Superfamily BVB96_16640 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BVB96_16645 ENOG4107QR9 Iron-sulfur cluster binding protein BVB96_16655 ENOG4106P55 Transcriptional regulator BVB96_16665 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BVB96_16705 ENOG4105TRI Hydrolase BVB96_16745 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BVB96_16775 ENOG4107QJQ Mate efflux family protein BVB96_16800 ENOG4105MZU cell filamentation protein BVB96_16805 ENOG4105EQ0 Major Facilitator superfamily BVB96_16810 ENOG4108JGH Tetr family transcriptional regulator BVB96_16825 ENOG4105C44 Serine transporter BVB96_16830 ENOG4105EJQ L-serine dehydratase BVB96_16850 ENOG4108JPW Aminotransferase BVB96_16875 ENOG4105DVH amino acid BVB96_16895 ENOG4108JQ1 Dehydrogenase BVB96_16915 ENOG4108AEY RNA polymerase sigma factor BVB96_16930 ENOG41082W1 Cupin 2, conserved barrel domain protein BVB96_16940 ENOG410874W AraC family transcriptional regulator BVB96_16990 ENOG4108ISG Major Facilitator BVB96_17000 ENOG4107MII Sugar-specific transcriptional regulator TrmB BVB96_17005 ENOG4105CZM Major Facilitator BVB96_17025 ENOG4105DA5 (ABC) transporter BVB96_17030 ENOG41069JR BVB96_17040 ENOG4105RXJ BVB96_17045 ENOG4105KPY Small multidrug resistance protein BVB96_17050 ENOG4105KBX Transcriptional regulator, TetR family BVB96_17065 ENOG4105CRW Short chain fatty acid transporter BVB96_17075 ENOG4105DYS nad(p)h dehydrogenase (quinone) BVB96_17105 ENOG4108JJB ABC transporter BVB96_17110 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BVB96_17135 ENOG4108K8S endonuclease I BVB96_17150 ENOG41067QW Transcriptional regulator BVB96_17160 ENOG4108Z66 YbaK ebsC protein BVB96_17165 ENOG4105CUT histidyl-tRNA synthetase BVB96_17180 ENOG4105KVH Transcriptional regulator BVB96_17185 ENOG4108RCM Nitroreductase BVB96_17210 ENOG4108PSK reductase BVB96_17220 ENOG4105CJ1 ABC, transporter BVB96_17280 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_17285 ENOG4105DKQ ROK family BVB96_17290 ENOG4106UW1 Major Facilitator superfamily BVB96_17295 ENOG4108UW5 maltose o-acetyltransferase BVB96_17305 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BVB96_17315 ENOG4105C31 Tryptophanyl-tRNA synthetase BVB96_17320 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BVB96_17345 ENOG4105DMQ Methyltransferase BVB96_17355 ENOG4105EV4 Multidrug resistance protein mdtH BVB96_17385 ENOG4105C37 (CBS) domain BVB96_17400 ENOG4105DDN Pentapeptide repeat-containing protein BVB96_17405 ENOG4105XDF Protein of unknown function (DUF1272) BVB96_17410 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BVB96_17415 ENOG4105CMG Carbohydrate kinase BVB96_17420 ENOG4105C6Z Gluconate BVB96_17425 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BVB96_17440 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BVB96_17445 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BVB96_17450 ENOG4105CIS alcohol dehydrogenase BVB96_17455 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BVB96_17475 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BVB96_17480 ENOG4105D4Y metalloprotease BVB96_17500 ENOG4105CV8 reductase BVB96_17505 ENOG4105F27 Major Facilitator BVB96_17520 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BVB96_17525 ENOG4105C44 Serine transporter BVB96_17560 ENOG4105KVH Transcriptional regulator BVB96_17565 ENOG4108TZY GntR Family Transcriptional Regulator BVB96_17570 ENOG4105D9R oxidoreductase BVB96_17575 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BVB96_17580 ENOG4105KVH Transcriptional regulator BVB96_17585 ENOG4105KVH Transcriptional regulator BVB96_17620 ENOG4105JAB phenazine biosynthesis protein, phzf family BVB96_17630 ENOG4105CHR reductase BVB96_17650 ENOG4105KVH Transcriptional regulator BVB96_17675 ENOG4108ZJ4 polysaccharide deacetylase BVB96_17725 ENOG4105KAF membrAne BVB96_17755 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BVB96_17775 ENOG4107YXZ hydrolase, family 25 BVB96_17800 ENOG4105ED2 Beta-lactamase BVB96_17810 ENOG4105H3G oxidoreductase BVB96_17845 ENOG4105CIS alcohol dehydrogenase BVB96_17885 ENOG4108TN2 lmbE family BVB96_17895 ENOG4107R3E Citrate transporter BVB96_17915 ENOG4108MES Periplasmic binding protein BVB96_17925 ENOG4105EHG Permease protein BVB96_17930 ENOG4105DQ5 transport system permease protein BVB96_17935 ENOG4105NX3 Membrane BVB96_17940 ENOG4107ZY0 Phenazine biosynthesis-like protein BVB96_17960 ENOG4107CUJ Protein of unknown function (DUF2690) BVB96_17970 ENOG4107V2S Transcriptional regulator BVB96_17990 ENOG4105C98 muts2 protein BVB96_18005 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BVB96_18010 ENOG4105DPN Oligoendopeptidase f BVB96_18015 ENOG4108A04 Beta-lactamase BVB96_18045 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BVB96_18070 ENOG41082BM Transcriptional regulator, arsr family BVB96_18075 ENOG4105CIS alcohol dehydrogenase BVB96_18110 ENOG4105C09 Bile acid BVB96_18115 ENOG4105CQB FAD linked oxidase domain protein BVB96_18145 ENOG4108UT6 Transferase hexapeptide repeat containing protein BVB96_18155 ENOG4105K64 Glycosyl transferase, family 2 BVB96_18160 ENOG4105E39 Enoyl-CoA hydratase BVB96_18170 ENOG4105KT7 mgtC SapB transporter BVB96_18185 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_18190 ENOG41073R8 VanW family BVB96_18200 ENOG4108R1P BVB96_18220 ENOG4105VEQ Cold shock protein BVB96_18240 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BVB96_18260 ENOG410904N short-chain dehydrogenase reductase BVB96_18285 ENOG4108IA2 Sodium pantothenate symporter BVB96_18295 ENOG4105C26 Dehydrogenase BVB96_18300 ENOG4105CHR reductase BVB96_18310 ENOG4105EWU Squalene--hopene cyclase BVB96_18320 ENOG4105FR1 rard protein BVB96_18325 ENOG410696E Membrane BVB96_18340 ENOG4105D1F ATP-binding protein BVB96_18350 ENOG4108ZAF Molybdopterin BVB96_18355 ENOG4105CVM Molybdenum cofactor synthesis domain protein BVB96_18360 ENOG4105D06 uba thif-type nad fad binding protein BVB96_18365 ENOG4105TMB Formate nitrite transporter BVB96_18380 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BVB96_18385 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BVB96_18395 ENOG4108JB9 formate dehydrogenase BVB96_18405 ENOG4105E1K spore germination protein BVB96_18465 ENOG4107QJT sodium dicarboxylate symporter BVB96_18470 ENOG4108KGH TRANSCRIPTIONal BVB96_18480 ENOG4105EMN RNA polymerase sigma factor BVB96_18505 ENOG4105CIG ABC transporter BVB96_18515 ENOG4105D9R oxidoreductase BVB96_18525 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVB96_18535 ENOG4105K4P CoA-binding domain protein BVB96_18540 ENOG4105C0H protease BVB96_18545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_18555 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BVB96_18560 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BVB96_18565 ENOG4105W8X HesB YadR YfhF-family protein BVB96_18595 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BVB96_18605 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BVB96_18615 ENOG4108JJA ABC, transporter BVB96_18620 ENOG4108I0Z Aconitate hydratase BVB96_18650 ENOG4105E5W Transporter BVB96_18660 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BVB96_18680 ENOG4107F3J Amp-dependent synthetase and ligase BVB96_18685 ENOG4107ZYJ bioY protein BVB96_18690 ENOG4105CEY Amp-dependent synthetase and ligase BVB96_18745 ENOG4107AYK membrAne BVB96_18760 ENOG4105BZU Histidine kinase BVB96_18765 ENOG4105FBA Phospholipase Carboxylesterase BVB96_18770 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BVB96_18775 ENOG4105CK7 Sodium proline symporter BVB96_18780 ENOG4105CBC glutamate synthase BVB96_18785 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVB96_18790 ENOG4108VJ1 Transcriptional regulator (CarD family BVB96_18795 ENOG4108903 Formimidoylglutamase BVB96_18820 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BVB96_18885 ENOG4107QIV Cytochrome c biogenesis protein BVB96_18900 ENOG4107RSM transcriptional regulator BVB96_18905 ENOG4105VAW lrga family BVB96_18910 ENOG41067MG lrgb family BVB96_18935 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BVB96_18950 ENOG4105BZ1 (ABC) transporter BVB96_18955 ENOG4105BZ1 (ABC) transporter BVB96_18980 ENOG4105D7V transposase BVB96_19000 ENOG4105D5T phosphonate abc transporter BVB96_19020 ENOG4108SVB resolvase BVB96_19040 ENOG4105K7K Transcriptional regulator BVB96_19085 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BVB96_19090 ENOG4105XSJ toxin secretion phage lysis holin BVB96_19285 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BVB96_19400 ENOG4105C5F glutamine synthetase BVB96_19405 ENOG4105KV4 Transcriptional regulator BVB96_19410 ENOG4105CXI aluminum resistance protein BVB96_19415 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BVB96_19420 ENOG4105EN6 Membrane BVB96_19425 ENOG4106F1P AAA ATPase, central domain protein BVB96_19455 ENOG41069ER domain protein BVB96_19460 ENOG4105DM4 PTS System BVB96_19465 ENOG4105DE4 1-phosphofructokinase BVB96_19470 ENOG4105E98 transcriptional regulator DeoR family BVB96_19480 ENOG4108SJC Membrane BVB96_19495 ENOG4105C85 amino acid BVB96_19525 ENOG4105TMB Formate nitrite transporter BVB96_19530 ENOG4105K70 DNA-binding protein BVB96_19535 ENOG4105C59 p-type ATPase BVB96_19540 ENOG410681U heavy metal transport detoxification protein BVB96_19545 ENOG4105VPX protein, conserved in bacteria BVB96_19555 ENOG4105NIV Esterase BVB96_19560 ENOG4105E0A ABC, transporter BVB96_19595 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BVB96_19600 ENOG4105D03 DNA-3-methyladenine glycosylase II BVB96_19630 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_19635 ENOG4105BZU Histidine kinase BVB96_19655 ENOG41067MG lrgb family BVB96_19670 ENOG4107TTQ Alpha beta hydrolase fold BVB96_19675 ENOG4107YEI lmbE family BVB96_19700 ENOG4105F0V Cell wall hydrolase BVB96_19705 ENOG4107R6R udp-galactopyranose mutase BVB96_19710 ENOG4105E0M Sulfatase BVB96_19715 ENOG410890F Dynamin family BVB96_19725 ENOG4107QHE Choloylglycine hydrolase BVB96_19750 ENOG4105DA5 (ABC) transporter BVB96_19775 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BVB96_19780 ENOG4105DQU oxidoreductase, subunit beta BVB96_19785 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BVB96_19790 ENOG4108IGT Dipeptidase BVB96_19795 ENOG4105MCT stage V sporulation protein S BVB96_19800 ENOG4105D48 metallophosphoesterase BVB96_19825 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BVB96_19840 ENOG4105XZV Protein of unknown function (DUF3243) BVB96_19845 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BVB96_19865 ENOG4105UIB (ABC) transporter BVB96_19870 ENOG4105UIB (ABC) transporter BVB96_19875 ENOG4108JQ9 ABC transporter BVB96_19880 ENOG4105DIH basic membrane BVB96_19885 ENOG4105FDP GntR family transcriptional regulator BVB96_19890 ENOG4107QZI cell division protein FtsK BVB96_19900 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BVB96_19915 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVB96_19925 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BVB96_19930 ENOG4108S0H Dipicolinic acid synthetase, b subunit BVB96_19935 ENOG4105E35 Dipicolinate synthase subunit A BVB96_19950 ENOG4105C1V Peptidase, M16 BVB96_19970 ENOG4105DTN riboflavin biosynthesis protein ribF BVB96_19975 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BVB96_19985 ENOG4105W7A Protein of unknown function (DUF503) BVB96_19995 ENOG4105VHM ribosomal protein BVB96_20000 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BVB96_20005 ENOG4105CHV Transcription elongation factor NusA BVB96_20015 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BVB96_20030 ENOG4105DZP Membrane-associated zinc metalloprotease BVB96_20035 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BVB96_20040 ENOG4105KNE Phosphatidate cytidylyltransferase BVB96_20085 ENOG4108HE4 integrase family BVB96_20095 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BVB96_20105 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BVB96_20120 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BVB96_20145 ENOG4105VB6 UPF0109 protein BVB96_20165 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BVB96_20170 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BVB96_20185 ENOG4105CHR reductase BVB96_20190 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BVB96_20205 ENOG4105CB5 ATP-dependent DNA helicase recG BVB96_20210 ENOG4105DP4 dak2 domain fusion protein ylov BVB96_20215 ENOG4108ZAA Alkaline-shock protein BVB96_20230 ENOG4105FJ0 thiamine BVB96_20235 ENOG4105DJV ribulose-phosphate 3-epimerase BVB96_20240 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BVB96_20245 ENOG4105D9P serine threonine protein kinase BVB96_20250 ENOG4108ZF3 Phosphatase BVB96_20260 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BVB96_20270 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BVB96_20275 ENOG4105C25 Primosomal protein n' BVB96_20280 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BVB96_20300 ENOG4105DSJ YicC domain protein BVB96_20310 ENOG4105F23 Fibronectin-binding protein BVB96_20315 ENOG4105DC7 peptidase M24 BVB96_20375 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BVB96_20400 ENOG4105C34 Pseudouridine synthase BVB96_20415 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BVB96_20425 ENOG4105DBK s4 domain protein BVB96_20430 ENOG41067XK integral membrane protein BVB96_20440 ENOG4105DFA alanine racemase domain protein BVB96_20445 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BVB96_20450 ENOG4105WR5 sporulation protein, YlmC YmxH family BVB96_20460 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_20470 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BVB96_20475 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BVB96_20480 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BVB96_20485 ENOG4105D4A Cell wall formation (By similarity) BVB96_20490 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BVB96_20495 ENOG4105CNI cell division protein FtsW BVB96_20510 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BVB96_20515 ENOG4105CJN penicillin-binding protein BVB96_20520 ENOG4105CJN penicillin-binding protein BVB96_20525 ENOG41068DC Essential cell division protein (By similarity) BVB96_20545 ENOG4107S3C Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BVB96_20565 ENOG4105KNH Nucleic acid-binding protein BVB96_20615 ENOG4105XSJ toxin secretion phage lysis holin BVB96_20695 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BVB96_20705 ENOG4105CAR Terminase, large subunit BVB96_20810 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BVB96_20825 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_20875 ENOG4108IMY Transcriptional regulator BVB96_20910 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BVB96_20920 ENOG41063PX domain protein BVB96_20925 ENOG4105D78 K07001 NTE family protein BVB96_20930 ENOG4105H20 Sporulation integral membrane protein YlbJ BVB96_20940 ENOG4106H78 methyltransferase BVB96_20960 ENOG4107TB6 phosphoglycerate mutase BVB96_20975 ENOG4106UY4 Inherit from COG: Scp-like extracellular BVB96_21025 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BVB96_21035 ENOG4105CNI cell division protein FtsW BVB96_21050 ENOG4108IAB Phoh family BVB96_21070 ENOG4105QA2 BVB96_21075 ENOG4105CI3 gtp-binding protein typa BVB96_21085 ENOG4105ECY inositol monophosphatase BVB96_21105 ENOG4105CXN decarboxylase BVB96_21155 ENOG4105CPP Dehydrogenase, E1 component BVB96_21170 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BVB96_21175 ENOG4108X4Q Hydrolase BVB96_21190 ENOG4105CN5 Metallo-Beta-Lactamase BVB96_21195 ENOG4107ZYR domain protein BVB96_21230 ENOG4108XRC Protein of unknown function (DUF458) BVB96_21240 ENOG4107IN1 Protein of unknown function (DUF1797) BVB96_21255 ENOG4105EPM Diguanylate phosphodiesterase BVB96_21260 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BVB96_21290 ENOG4105UIN BVB96_21355 ENOG4108HGU Histidine kinase BVB96_21365 ENOG4105CHM Aminotransferase BVB96_21370 ENOG4105FKQ transcriptional regulator BVB96_21375 ENOG4105EG2 ABC transporter, permease BVB96_21385 ENOG4107FKK extracellular solute-binding protein family 1 BVB96_21395 ENOG4105CG3 alpha amylase, catalytic region BVB96_21440 ENOG4105CHU acetyl-coa acetyltransferase BVB96_21480 ENOG4105K7K Transcriptional regulator BVB96_21485 ENOG4105DTD Dehydrogenase BVB96_21495 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BVB96_21505 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BVB96_21530 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BVB96_21555 ENOG4106TD9 Diguanylate cyclase BVB96_21575 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BVB96_21590 ENOG4105CID antiterminator BVB96_21600 ENOG4105FDP GntR family transcriptional regulator BVB96_21610 ENOG4105CE4 GlcNAc 6-P deacetylase BVB96_21655 ENOG4107ZE5 PPIases accelerate the folding of proteins BVB96_21660 ENOG4105PTM secreted protein BVB96_21665 ENOG4105J7I hydrolase BVB96_21675 ENOG4105G6R Stage v sporulation protein ae BVB96_21685 ENOG4105CZ3 stage V sporulation protein ad BVB96_21690 ENOG41090VF Stage v sporulation protein ac BVB96_21710 ENOG4105C8J )-transporter BVB96_21715 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_21725 ENOG41082AN stage II sporulation protein BVB96_21730 ENOG4105DZ1 carboxypeptidase BVB96_21740 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BVB96_21745 ENOG4105DVE abc transporter atp-binding protein BVB96_21780 ENOG4105D7N magnesium and cobalt transport protein CorA BVB96_21805 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BVB96_21815 ENOG4105I3K Ferric uptake regulator, Fur family BVB96_21820 ENOG4105MZ9 stage II sporulation protein m BVB96_21840 ENOG4105CPC Aldo Keto reductase BVB96_21850 ENOG4105RHY Pfam:UPF0157 BVB96_21870 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BVB96_21880 ENOG4105ETE Transcriptional regulator (LacI family BVB96_21885 ENOG4108YM7 Gcn5-related n-acetyltransferase BVB96_21905 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BVB96_21910 ENOG4108R6K riboflavin synthase, subunit alpha BVB96_21930 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BVB96_21935 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BVB96_21940 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BVB96_21945 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BVB96_21955 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BVB96_21970 ENOG4105DFD Na H antiporter BVB96_21975 ENOG4105CGH 5'-nucleotidase BVB96_22015 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BVB96_22030 ENOG4108IXY short-chain dehydrogenase reductase BVB96_22035 ENOG41069FQ Metallo-beta-lactamase superfamily BVB96_22040 ENOG4105II7 pyrroline-5-carboxylate reductase BVB96_22045 ENOG4105EJQ L-serine dehydratase BVB96_22075 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BVB96_22085 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BVB96_22090 ENOG4105D9U N-acetyltransferase BVB96_22105 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BVB96_22110 ENOG4108QEG Membrane BVB96_22115 ENOG4105CDA abc transporter atp-binding protein BVB96_22120 ENOG4105E5Q amino acid AbC transporter BVB96_22125 ENOG4108HW3 (ABC) transporter BVB96_22140 ENOG4105G7B Protein of unknown function (DUF2992) BVB96_22145 ENOG4105E09 nadh pyrophosphatase BVB96_22155 ENOG4105C7S Dehydrogenase BVB96_22160 ENOG4105CPP Dehydrogenase, E1 component BVB96_22180 ENOG4107RDP Dehydrogenase BVB96_22195 ENOG4108JUB Transcriptional regulator BVB96_22205 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BVB96_22220 ENOG4107QQR Sporulation BVB96_22230 ENOG4105S1Z Stage IV sporulation protein B BVB96_22235 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BVB96_22245 ENOG4105DX0 Hemolysin A BVB96_22255 ENOG4105CTB Polyprenyl synthetase BVB96_22280 ENOG4108ZSR alkaline shock protein BVB96_22285 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BVB96_22310 ENOG410644B Stage III sporulation protein af BVB96_22320 ENOG4105KQ4 Stage iii sporulation protein ad BVB96_22325 ENOG4108CQH stage III sporulation protein AC BVB96_22330 ENOG4105KR5 Stage iii sporulation protein BVB96_22335 ENOG4105CD2 stage iii sporulation protein aa BVB96_22360 ENOG4105DC7 peptidase M24 BVB96_22375 ENOG4105CBJ Metal-dependent enzyme BVB96_22385 ENOG4107YBY Hydrolase BVB96_22405 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BVB96_22410 ENOG4105WZW rhodanese family BVB96_22430 ENOG41080TC multidrug resistance protein BVB96_22470 ENOG4105CJ1 ABC, transporter BVB96_22475 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BVB96_22510 ENOG4105C0D helicase BVB96_22635 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BVB96_22650 ENOG4105C28 cystathionine BVB96_22655 ENOG4105C28 cystathionine BVB96_22675 ENOG4105C5X domain protein BVB96_22685 ENOG4105DKQ ROK family BVB96_22695 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BVB96_22710 ENOG4108UTW Plays a role in the regulation of phosphate uptake BVB96_22715 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BVB96_22720 ENOG4105E2Z phosphate ABC transporter (Permease BVB96_22725 ENOG4105C8U phosphate abc transporter BVB96_22730 ENOG4105PWN phosphate abc transporter BVB96_22735 ENOG4107RF6 penicillin-binding protein BVB96_22745 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BVB96_22770 ENOG4105N80 Ferric uptake regulator, Fur family BVB96_22780 ENOG4105FDK ABC transporter BVB96_22785 ENOG4108JYZ YitT family BVB96_22790 ENOG41069ZM Protein of unknown function (DUF2624) BVB96_22815 ENOG4105EGD dinuclear metal center protein, YbgI family BVB96_22830 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_22835 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BVB96_22870 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BVB96_22875 ENOG4105KG3 cytidine deaminase BVB96_22880 ENOG4107YR5 Diacylglycerol kinase BVB96_22890 ENOG4105CTJ Metal Dependent Phosphohydrolase BVB96_22895 ENOG4105C9A Phoh family BVB96_22910 ENOG41068P3 sporulation protein YqfC BVB96_22915 ENOG4105KTH gatB Yqey BVB96_22930 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BVB96_22935 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BVB96_22955 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BVB96_22965 ENOG4105CSA Coproporphyrinogen iii oxidase BVB96_22970 ENOG4105KVH Transcriptional regulator BVB96_22995 ENOG4105TQK DNA polymerase iii, delta' subunit BVB96_23005 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BVB96_23010 ENOG4108UK2 deaminase BVB96_23015 ENOG4105KQC Competence protein BVB96_23025 ENOG4105DXX methyltransferase BVB96_23035 ENOG4108WF2 Metal Dependent Phosphohydrolase BVB96_23045 ENOG410812S Rna-binding protein BVB96_23055 ENOG4105CQW ribosome biogenesis GTPase YqeH BVB96_23060 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BVB96_23075 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_23095 ENOG4108TVJ Nitroreductase BVB96_23110 ENOG4105G6Z alkaline phosphatase BVB96_23120 ENOG4108MUZ hydrolase BVB96_23155 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BVB96_23160 ENOG4105MIR Phenylalanine 4-monooxygenase BVB96_23170 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_23210 ENOG4105S6R Iron-hydroxamate transporter permease subunit BVB96_23215 ENOG4108V5C ABC transporter BVB96_23230 ENOG4108EKI Dehydrogenase BVB96_23235 ENOG4105C28 cystathionine BVB96_23265 ENOG4107XRG penicillin-binding protein BVB96_23280 ENOG4105CFP Peptidase U32 BVB96_23285 ENOG4105XYU peptidase (U32 family) BVB96_23290 ENOG4108VQJ O-methyltransferase BVB96_23295 ENOG4105HHA aminodeoxychorismate lyase BVB96_23315 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BVB96_23325 ENOG4105C02 permease BVB96_23340 ENOG41060CR BVB96_23345 ENOG4105C7H Helicase, RecD TraA family BVB96_23355 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BVB96_23360 ENOG4105C3J Cysteine desulfurase BVB96_23370 ENOG4105D1H recombination factor protein RarA BVB96_23375 ENOG4108VCI transcription factor, rsfa family BVB96_23380 ENOG4105CUZ uba thif-type nad fad binding protein BVB96_23390 ENOG4105CUT histidyl-tRNA synthetase BVB96_23410 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BVB96_23420 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BVB96_23425 ENOG41076HS cation diffusion facilitator family transporter BVB96_23430 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BVB96_23440 ENOG4105CKP Polysaccharide Biosynthesis Protein BVB96_23445 ENOG4108QG2 Membrane BVB96_23455 ENOG4105VIE preprotein translocase, subunit YajC BVB96_23470 ENOG41061AI Protein of unknown function (DUF2905) BVB96_23485 ENOG4108HUF Transporter BVB96_23495 ENOG4108IPJ Membrane BVB96_23500 ENOG4108IPJ Membrane BVB96_23505 ENOG41082BM Transcriptional regulator, arsr family BVB96_23530 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BVB96_23535 ENOG4108IYU L-aspartate oxidase BVB96_23550 ENOG4108RPX mosc domain containing protein BVB96_23555 ENOG4105CQC Prephenate dehydratase BVB96_23585 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BVB96_23600 ENOG4105X36 (ribosomal) protein BVB96_23610 ENOG4105C03 ribonuclease BVB96_23625 ENOG4107QMS site-determining protein BVB96_23640 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BVB96_23645 ENOG4105DFF Rod shape-determining protein mreb BVB96_23670 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BVB96_23675 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BVB96_23685 ENOG41068KH stage VI sporulation protein D BVB96_23695 ENOG4105D52 delta-aminolevulinic acid dehydratase BVB96_23720 ENOG4105K56 Transcriptional regulator BVB96_23740 ENOG4108IUQ atp-dependent protease BVB96_23770 ENOG4108QCI YvbH-like oligomerisation region BVB96_23795 ENOG4105M59 Phosphodiesterase, mj0936 family BVB96_23800 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BVB96_23810 ENOG4108XJQ germination protein BVB96_23820 ENOG4108PCX Major Facilitator BVB96_23830 ENOG4105KBX Transcriptional regulator, TetR family BVB96_23845 ENOG4105PFC Transcriptional regulator BVB96_23860 ENOG4105DZC cytosine deaminase BVB96_23865 ENOG4105DZC cytosine deaminase BVB96_23870 ENOG4105DEF Extracellular solute-binding protein, family 5 BVB96_23875 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVB96_23890 ENOG4108JQ7 (ABC) transporter BVB96_23900 ENOG4105DY9 regulatoR BVB96_23915 ENOG41067S9 phage shock protein C, PspC BVB96_23920 ENOG4108JCI Transcriptional regulator BVB96_23930 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BVB96_23935 ENOG4108Z40 Transcriptional regulator BVB96_23940 ENOG4105RHA ABC transporter, permease BVB96_23945 ENOG4108IUX (ABC) transporter BVB96_23950 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BVB96_23955 ENOG4105ER2 Ompa motb domain protein BVB96_23960 ENOG4105ER2 Ompa motb domain protein BVB96_23965 ENOG4105E14 MotA TolQ exbB proton channel BVB96_23970 ENOG4108VXD carboxy-peptidase BVB96_23980 ENOG4105E33 succinate dehydrogenase BVB96_23990 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BVB96_24005 ENOG4105K63 Thioredoxin BVB96_24010 ENOG4105C10 Electron transfer flavoprotein BVB96_24015 ENOG4105BZJ Electron transfer flavoprotein BVB96_24020 ENOG41060WC Enoyl-CoA hydratase BVB96_24025 ENOG4107Z3H Transcriptional regulator, TetR family BVB96_24030 ENOG4105CEY Amp-dependent synthetase and ligase BVB96_24045 ENOG4105J76 Periplasmic binding protein BVB96_24050 ENOG4105S6R Iron-hydroxamate transporter permease subunit BVB96_24095 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_24110 ENOG4105DR4 Methyltransferase BVB96_24125 ENOG4105KFN sortase, SrtB family BVB96_24130 ENOG4105E0A ABC, transporter BVB96_24145 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BVB96_24155 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BVB96_24165 ENOG4105FE9 pseudouridine synthase BVB96_24180 ENOG4105DCG PHP domain protein BVB96_24215 ENOG4105C5S asparaginyl-tRNA synthetase BVB96_24220 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BVB96_24230 ENOG4108RWN rrna methyltransferase BVB96_24265 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVB96_24270 ENOG4105CW7 secretion protein, HlyD family BVB96_24275 ENOG4108JGH Tetr family transcriptional regulator BVB96_24280 ENOG4105CN9 Peptidase m42 family protein BVB96_24300 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BVB96_24305 ENOG4105C22 threonyL-tRNA synthetase BVB96_24310 ENOG4108TDW sporulation protein YtxC BVB96_24330 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BVB96_24340 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BVB96_24345 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BVB96_24355 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BVB96_24360 ENOG4105C2M dna polymerase I BVB96_24365 ENOG4105BZU Histidine kinase BVB96_24370 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_24395 ENOG4108HMX isocitrate dehydrogenase (NADP) BVB96_24400 ENOG4105BZN citrate synthase BVB96_24415 ENOG4108REF Sporulation integral membrane protein ytvi BVB96_24420 ENOG4105FS0 cytoplasmic membrane protein BVB96_24445 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BVB96_24450 ENOG4105C6K Malic enzyme BVB96_24455 ENOG4105C0B DNA polymerase III (alpha subunit) BVB96_24460 ENOG4105VV2 BVB96_24470 ENOG4105SFS phosphoesterase RecJ domain protein BVB96_24510 ENOG4105DC7 peptidase M24 BVB96_24550 ENOG4105Z7P Acetyltransferase (GNAT) family BVB96_24555 ENOG41082W1 Cupin 2, conserved barrel domain protein BVB96_24565 ENOG4105VZ8 Transcriptional regulator BVB96_24585 ENOG4107YZX Universal stress protein BVB96_24635 ENOG4108JYZ YitT family BVB96_24655 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BVB96_24665 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BVB96_24670 ENOG4105KBJ sporulation protein ytfj BVB96_24685 ENOG4105EFZ amidohydrolase BVB96_24695 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BVB96_24720 ENOG4106KR7 LysR family Transcriptional regulator BVB96_24740 ENOG4105C28 cystathionine BVB96_24765 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BVB96_24775 ENOG4105EMN RNA polymerase sigma factor BVB96_24790 ENOG4105F1V Acetoin utilization protein BVB96_24795 ENOG4105W87 Cbs domain BVB96_24800 ENOG4105DGU Histone deacetylase BVB96_24815 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVB96_24825 ENOG4107SNB ankyrin repeat protein YahD BVB96_24830 ENOG4105EP9 oxidoreductase BVB96_24860 ENOG4105ETE Transcriptional regulator (LacI family BVB96_24885 ENOG4105C88 aminopeptidase BVB96_24930 ENOG4108VDD TRNA binding domain protein BVB96_24960 ENOG4105C8F Beta-lactamase domain protein BVB96_24975 ENOG4108V15 phosphotransferase enzyme family BVB96_24980 ENOG4108IUM Glycogen debranching enzyme BVB96_24995 ENOG4107QSE Dipeptidase BVB96_25000 ENOG4105YW5 deoR family transcriptional regulator BVB96_25015 ENOG4105CBX hi0933 family BVB96_25065 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BVB96_25070 ENOG4105CSC Glucose uptake protein BVB96_25085 ENOG4108ZAF Molybdopterin BVB96_25090 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BVB96_25095 ENOG4105CVM Molybdenum cofactor synthesis domain protein BVB96_25105 ENOG4105D06 uba thif-type nad fad binding protein BVB96_25110 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BVB96_25130 ENOG41085GJ domain protein BVB96_25140 ENOG4105DWV Homoserine O-trans-acetylase BVB96_25150 ENOG4108B31 Spore germination protein BVB96_25185 ENOG410605W Major Facilitator BVB96_25190 ENOG4107S91 Sodium hydrogen exchanger BVB96_25195 ENOG4105NCW Trka-c domain protein BVB96_25210 ENOG4105C19 ABC transporter BVB96_25230 ENOG4105N5T Radical SAM Protein BVB96_25240 ENOG4105DA5 (ABC) transporter BVB96_25270 ENOG4105E8V Alpha Beta Hydrolase Fold protein BVB96_25275 ENOG4108Z0R Transferase BVB96_25280 ENOG4105YVM Phosphoesterase, PA-phosphatase related BVB96_25285 ENOG4105BZF Glycosyl transferase (Group 1 BVB96_25295 ENOG4108RIR Molybdenum cofactor biosynthesis protein BVB96_25355 ENOG4105EGD dinuclear metal center protein, YbgI family BVB96_25360 ENOG4105BZU Histidine kinase BVB96_25365 ENOG4105BZU Histidine kinase BVB96_25370 ENOG4107S9D Alpha beta hydrolase BVB96_25390 ENOG4105D2X ABC transporter substrate-binding protein BVB96_25400 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BVB96_25420 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BVB96_25465 ENOG4108V2W Carbonate dehydratase BVB96_25470 ENOG4105C4M (Ubiquinol oxidase) subunit I BVB96_25475 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BVB96_25525 ENOG41087YS Phage shock protein A BVB96_25560 ENOG4105BZU Histidine kinase BVB96_25565 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_25590 ENOG4108UGV hypoxanthine phosphoribosyltransferase BVB96_25600 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BVB96_25635 ENOG4107ZTW SNARE associated Golgi BVB96_25650 ENOG4105C19 ABC transporter BVB96_25655 ENOG41086D8 Transcriptional regulator BVB96_25695 ENOG4105C6Z Gluconate BVB96_25700 ENOG4105FDP GntR family transcriptional regulator BVB96_25720 ENOG41069H0 dihydroorotase EC 3.5.2.3 BVB96_25750 ENOG4105DTQ mandelate racemase muconate lactonizing BVB96_25760 ENOG4108IPT Naphthoate synthase BVB96_25765 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BVB96_25770 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BVB96_25775 ENOG4105E4F Isochorismate synthase BVB96_25780 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BVB96_25790 ENOG4105VEQ Cold shock protein BVB96_25815 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BVB96_25825 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BVB96_25850 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BVB96_25950 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BVB96_25995 ENOG4105KT7 mgtC SapB transporter BVB96_26000 ENOG4107PBV potassium channel BVB96_26010 ENOG4107QYV phosphohexose isomerase BVB96_26020 ENOG4105WG9 Conserved Protein BVB96_26030 ENOG4105CHM Aminotransferase BVB96_26035 ENOG4108ZB6 transcriptional regulator AsnC family BVB96_26040 ENOG4105C5I Dehydrogenase BVB96_26045 ENOG4108MUZ hydrolase BVB96_26055 ENOG4105C87 Aminotransferase class I and II BVB96_26070 ENOG4105Y38 Kinase-associated protein B BVB96_26080 ENOG4107R3E Citrate transporter BVB96_26100 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BVB96_26105 ENOG4105KA0 thioesterase Superfamily protein BVB96_26125 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BVB96_26145 ENOG41069ER domain protein BVB96_26160 ENOG4105CEP NADH dehydrogenase BVB96_26190 ENOG4105EWC Purine nucleoside phosphorylase BVB96_26210 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BVB96_26235 ENOG4108JJA ABC, transporter BVB96_26240 ENOG4105C4B ABC transporter, permease BVB96_26250 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BVB96_26295 ENOG41083MR nifu domain-containing protein BVB96_26310 ENOG4108W5N phosphatidylglycerophosphatase a BVB96_26320 ENOG4105DYS nad(p)h dehydrogenase (quinone) BVB96_26325 ENOG4105D4U had-superfamily hydrolase, subfamily iia BVB96_26340 ENOG4105CBT Fructose-1,6-bisphosphatase BVB96_26360 ENOG4105MMD transcriptional regulator BVB96_26365 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BVB96_26370 ENOG4107TXC Transcriptional regulator BVB96_26375 ENOG41090T1 Membrane BVB96_26400 ENOG4105FAA peptidase M23 BVB96_26410 ENOG4105KZD Domain of unknown function (DUF1805) BVB96_26415 ENOG4107R8B 5'-nucleotidase BVB96_26435 ENOG4105DIW FeS assembly protein SUFB BVB96_26440 ENOG4108UNV SUF system FeS assembly protein, NifU family BVB96_26445 ENOG4105C9B Cysteine desulfurase BVB96_26450 ENOG4105JRK feS assembly protein SufD BVB96_26455 ENOG4105C3K feS assembly ATPase SufC BVB96_26460 ENOG4105D01 (LipO)protein BVB96_26465 ENOG4105D01 (LipO)protein BVB96_26470 ENOG4108UMI ABC transporter, permease BVB96_26505 ENOG41080E8 Transcriptional regulator, Spx MgsR family BVB96_26560 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BVB96_26590 ENOG4108W8B Beta-lactamase domain protein BVB96_26595 ENOG4105C1G acyl-Coa dehydrogenase BVB96_26605 ENOG4105CHU acetyl-coa acetyltransferase BVB96_26625 ENOG4105DZ1 carboxypeptidase BVB96_26645 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BVB96_26665 ENOG4108SUT Major Facilitator Superfamily BVB96_26670 ENOG4107R7I amino acid BVB96_26680 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BVB96_26690 ENOG4107AYK membrAne BVB96_26725 ENOG4107ZTW SNARE associated Golgi BVB96_26735 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BVB96_26740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_26745 ENOG4105BZU Histidine kinase BVB96_26755 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BVB96_26770 ENOG4105VG1 fes assembly suf system protein BVB96_26795 ENOG4107S91 Sodium hydrogen exchanger BVB96_26800 ENOG4105NCW Trka-c domain protein BVB96_26815 ENOG4108RMU ferritin dps family protein BVB96_26830 ENOG4108URH decarboxylase BVB96_26855 ENOG4105D9N nucleoside BVB96_26860 ENOG4105D9N nucleoside BVB96_26875 ENOG4108RYK Nad-dependent epimerase dehydratase BVB96_26905 ENOG4105CV8 reductase BVB96_26910 ENOG4105F27 Major Facilitator BVB96_26915 ENOG4105KVH Transcriptional regulator BVB96_26930 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BVB96_26935 ENOG4105D4A Cell wall formation (By similarity) BVB96_26945 ENOG4105C8Q Methyl-accepting chemotaxis BVB96_26955 ENOG4105WMR Protein CrcB homolog BVB96_26960 ENOG4105WMR Protein CrcB homolog BVB96_26975 ENOG4108MK9 spermidine N(1)-acetyltransferase BVB96_26980 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BVB96_27000 ENOG4108IPW abc transporter atp-binding protein BVB96_27005 ENOG4105CM4 permease protein BVB96_27040 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BVB96_27050 ENOG4105XZU Preprotein translocase, subunit SecG BVB96_27055 ENOG41067MG lrgb family BVB96_27165 ENOG4105EFC phage portal protein HK97 family BVB96_27190 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BVB96_27200 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BVB96_27205 ENOG4105CP7 Triose-phosphate isomerase BVB96_27230 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_27250 ENOG41090VF Stage v sporulation protein ac BVB96_27255 ENOG4105CZ3 stage V sporulation protein ad BVB96_27270 ENOG4105H67 Protein of unknown function (DUF421) BVB96_27275 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BVB96_27280 ENOG4105KRI phosphocarrier protein (HPr BVB96_27290 ENOG4105CHW UPF0052 protein BVB96_27300 ENOG4108Z4K mutator MutT protein BVB96_27310 ENOG4105C3M thioredoxin reductase BVB96_27320 ENOG4108S4C acetyltransferase BVB96_27340 ENOG41086DT Membrane protein of unknown function BVB96_27350 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BVB96_27355 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BVB96_27360 ENOG4105D7V transposase BVB96_27375 ENOG4107TXC Transcriptional regulator BVB96_27405 ENOG4105DUM transcriptional regulator, lysR family BVB96_27415 ENOG4108WS4 fmn reductase BVB96_27430 ENOG4105BZ1 (ABC) transporter BVB96_27440 ENOG4105CN1 protease BVB96_27445 ENOG4105CRP Part of the ABC transporter FtsEX involved in BVB96_27450 ENOG4105CAK Cell division ATP-binding protein ftsE BVB96_27465 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BVB96_27475 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BVB96_27480 ENOG4105MS2 ribosomal subunit Interface protein BVB96_27485 ENOG4105VEQ Cold shock protein BVB96_27490 ENOG41081UC Inherit from COG: Competence protein BVB96_27505 ENOG4105KVH Transcriptional regulator BVB96_27520 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BVB96_27525 ENOG4108KGH TRANSCRIPTIONal BVB96_27530 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BVB96_27535 ENOG4105C6Y Udp-glucose 6-dehydrogenase BVB96_27540 ENOG4105ESV Glycosyl transferase, family 4 BVB96_27550 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BVB96_27565 ENOG410901P UPF0249 protein BVB96_27570 ENOG4105F8D glycoside hydrolase family 4 BVB96_27575 ENOG4105VCP PTS System BVB96_27580 ENOG4105CK1 PTS System BVB96_27590 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BVB96_27595 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BVB96_27600 ENOG4105VCP PTS System BVB96_27610 ENOG4105VZJ PTS System BVB96_27625 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BVB96_27630 ENOG4105ECB domain protein BVB96_27635 ENOG4107RSM transcriptional regulator BVB96_27675 ENOG4105DAA L-lactate BVB96_27685 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BVB96_27695 ENOG4105E0M Sulfatase BVB96_27735 ENOG4105C94 Transporter BVB96_27745 ENOG41069ER domain protein BVB96_27770 ENOG4105KBK Zinc finger, swim domain protein BVB96_27775 ENOG4105C0D helicase BVB96_27805 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVB96_27815 ENOG4107RBB ABC transporter, permease BVB96_27820 ENOG4105C19 ABC transporter BVB96_27840 ENOG4105CXY transporter BVB96_27855 ENOG4105BZU Histidine kinase BVB96_27860 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_27865 ENOG4105CMR udp-glucose 4-epimerase BVB96_27880 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BVB96_27885 ENOG4105EY8 ABC transporter BVB96_27940 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BVB96_27955 ENOG4105FRN stage II sporulation protein BVB96_27990 ENOG4106778 Protein of unknown function (DUF1146) BVB96_27995 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BVB96_28000 ENOG4105C8S subunit m BVB96_28005 ENOG4105D65 subunit l BVB96_28030 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BVB96_28035 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BVB96_28045 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BVB96_28050 ENOG4105BZU Histidine kinase BVB96_28105 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BVB96_28110 ENOG41062M3 atp synthase BVB96_28140 ENOG4108YZG isomerase BVB96_28155 ENOG4108VGI doxx family BVB96_28160 ENOG4107XC4 flavin reductase domain protein, FMN-binding BVB96_28175 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BVB96_28185 ENOG4108ZXQ stage ii sporulation protein r BVB96_28190 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BVB96_28195 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BVB96_28210 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BVB96_28215 ENOG4105CBT Fructose-1,6-bisphosphatase BVB96_28225 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BVB96_28260 ENOG4105C1G acyl-Coa dehydrogenase BVB96_28265 ENOG4105C1G acyl-Coa dehydrogenase BVB96_28270 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BVB96_28280 ENOG4105DF6 Fe-S oxidoreductase BVB96_28295 ENOG4105BZU Histidine kinase BVB96_28325 ENOG4105BZU Histidine kinase BVB96_28330 ENOG4105KCT ABC transporter BVB96_28335 ENOG4108M15 ABC transporter BVB96_28340 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BVB96_28360 ENOG4105IIU Aminopeptidase BVB96_28380 ENOG4105EMN RNA polymerase sigma factor BVB96_28390 ENOG410684U Domain of unknown function (DUF1934) BVB96_28415 ENOG4105CYW agmatinase BVB96_28425 ENOG4105DXB Major Facilitator superfamily BVB96_28430 ENOG4107SWG transcriptional regulator MERR family BVB96_28435 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BVB96_28440 ENOG4105BZ4 penicillin-binding protein BVB96_28445 ENOG4108XFG YwhD family BVB96_28450 ENOG4108Z4T Peptidase M50 BVB96_28455 ENOG41069HH 4-oxalocrotonate tautomerase BVB96_28460 ENOG4105DCI Phosphohydrolase BVB96_28465 ENOG4108MES Periplasmic binding protein BVB96_28470 ENOG4105E0A ABC, transporter BVB96_28475 ENOG4105EHG Permease protein BVB96_28480 ENOG4105DQ5 transport system permease protein BVB96_28485 ENOG4105DQ5 transport system permease protein BVB96_28495 ENOG4108VCI transcription factor, rsfa family BVB96_28510 ENOG4108IJ2 phosphate acetyltransferase BVB96_28525 ENOG4108VKI Cell wall hydrolase BVB96_28545 ENOG4107SVH Potassium channel protein BVB96_28555 ENOG410667J hydrolase BVB96_28560 ENOG4105VCH membrane BVB96_28570 ENOG4108TU7 Inherit from COG: (ABC) transporter BVB96_28575 ENOG4105CJ1 ABC, transporter BVB96_28580 ENOG41090WU lipolytic protein G-D-S-L family BVB96_28595 ENOG4105D6E homoserine dehydrogenase BVB96_28620 ENOG4108Y4K DNA-binding transcriptional activator BVB96_28630 ENOG4105WH1 Two component transcriptional regulator luxr family BVB96_28640 ENOG4105DWF phosphomethylpyrimidine kinase BVB96_28645 ENOG4105BZU Histidine kinase BVB96_28650 ENOG4105VCD cytoplasmic protein BVB96_28655 ENOG4105D22 carbon starvation protein BVB96_28660 ENOG4105DY9 regulatoR BVB96_28665 ENOG41079KZ Major Facilitator Superfamily BVB96_28685 ENOG4105EN6 Membrane BVB96_28690 ENOG4106YBV Methyl-accepting chemotaxis BVB96_28700 ENOG4108S4H thioesterase Superfamily protein BVB96_28710 ENOG4105JEU Glycosyl transferase, family 2 BVB96_28715 ENOG4105C5H ABC transporter BVB96_28745 ENOG4105CKK Glycosyl transferase, family 2 BVB96_28750 ENOG41067SE Tetr family transcriptional regulator BVB96_28760 ENOG4105E0X reductase BVB96_28765 ENOG4106F5Q Membrane BVB96_28780 ENOG4105DY9 regulatoR BVB96_28785 ENOG4108HRK Histidine kinase BVB96_28790 ENOG4107RGD Major Facilitator superfamily BVB96_28810 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BVB96_28820 ENOG4105IW1 AmiS UreI transporter BVB96_28830 ENOG4105CMR udp-glucose 4-epimerase BVB96_28835 ENOG4108UT2 hemolysin iii BVB96_28845 ENOG4105C1J atp-dependent rna helicase BVB96_28860 ENOG4105DPN Oligoendopeptidase f BVB96_28880 ENOG4105C0H protease BVB96_28885 ENOG4105Q2H domain protein BVB96_28900 ENOG4105BZU Histidine kinase BVB96_28905 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVB96_28935 ENOG4105CDU Replicative dna helicase BVB96_28945 ENOG4105BZR domain protein BVB96_28950 ENOG4108XMW Membrane BVB96_28960 ENOG4108UUM single-stranded DNA-binding protein BVB96_28970 ENOG4105C3G gtp-binding protein BVB96_28975 ENOG4105VDK protein, conserved in bacteria BVB96_28980 ENOG4105D8X mechanosensitive ion channel BVB96_28985 ENOG4108ZDA Sporulation protein YyaC BVB96_28990 ENOG4105FA0 parb-like partition protein BVB96_28995 ENOG4107QJE Chromosome Partitioning Protein BVB96_29015 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BVB96_29025 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BVB96_29090 ENOG4105EKQ RNA-directed DNA polymerase BVB96_29190 ENOG4105EKQ RNA-directed DNA polymerase BVB96_29255 ENOG4106JUT Streptomycin 3''-adenylyltransferase BVB96_29315 ENOG4105CNU cell division protein FtsK BVB96_29545 ENOG4105DHF Membrane BVB96_29570 ENOG4106AKK s-layer domain-containing protein BVB96_29575 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BVB96_29605 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BVB96_29610 ENOG4105C6Y Udp-glucose 6-dehydrogenase BVB96_29700 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BVB96_29825 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BVB96_29855 ENOG4108IBT Inherit from COG: transposase BVB96_29865 ENOG4105DQ6 Transposase BVB96_29895 ENOG4108MEK Metal-binding protein YodA BVB96_29910 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BVB96_29940 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BVB96_30180 ENOG4107QJE Chromosome Partitioning Protein BVB96_30240 ENOG4105EWC Purine nucleoside phosphorylase BVB96_30330 ENOG4105C3F Signal peptidase i BVB96_30360 ENOG4105N14 lysine exporter protein LysE YggA BVB96_30410 ENOG4108J59 Extracellular solute-binding protein, family 5 BVB96_30425 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)