locus-tag	class	description
BVB96_00010	COG0592	DNA-directed DNA polymerase activity
BVB96_00015	COG2501	S4 domain
BVB96_00025	COG0187	DNA topoisomerase II activity
BVB96_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVB96_00065	COG0517	IMP dehydrogenase activity
BVB96_00065	COG0516	GMP reductase activity
BVB96_00070	COG1686	Belongs to the peptidase S11 family
BVB96_00100	COG1428	Deoxynucleoside kinase
BVB96_00105	COG1428	Deoxynucleoside kinase
BVB96_00110	COG1335	isochorismatase
BVB96_00120	COG0590	tRNA wobble adenosine to inosine editing
BVB96_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVB96_00185	COG1982	Orn Lys Arg decarboxylase major
BVB96_00195	COG0470	DNA polymerase III
BVB96_00200	COG1774	PSP1 C-terminal conserved region
BVB96_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVB96_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BVB96_00225	COG2002	toxin-antitoxin pair type II binding
BVB96_00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_00235	COG0084	hydrolase, TatD family'
BVB96_00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BVB96_00255	COG4466	Protein conserved in bacteria
BVB96_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVB96_00280	COG0251	oxidation-reduction process
BVB96_00295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVB96_00300	COG0193	aminoacyl-tRNA hydrolase activity
BVB96_00310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVB96_00315	COG2002	toxin-antitoxin pair type II binding
BVB96_00320	COG2244	polysaccharide biosynthetic process
BVB96_00325	COG3956	TIGRFAM MazG family protein
BVB96_00330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVB96_00350	COG1098	S1 RNA binding domain
BVB96_00365	COG2208	phosphoserine phosphatase activity
BVB96_00370	COG0037	tRNA processing
BVB96_00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVB96_00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVB96_00400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVB96_00405	COG0512	Glutamine amidotransferase of anthranilate synthase
BVB96_00410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVB96_00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVB96_00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVB96_00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVB96_00430	COG1396	sequence-specific DNA binding
BVB96_00435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVB96_00465	COG3880	PFAM UvrB UvrC protein
BVB96_00475	COG0542	response to heat
BVB96_00480	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BVB96_00490	COG4956	integral membrane protein (PIN domain superfamily)
BVB96_00510	COG1045	serine acetyltransferase
BVB96_00525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVB96_00530	COG3688	RNA-binding protein containing a PIN domain
BVB96_00540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVB96_00545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVB96_00550	COG0250	Participates in transcription elongation, termination and antitermination
BVB96_00575	COG2813	Specifically methylates the guanine in position
BVB96_00585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVB96_00590	COG1358	cellular component organization or biogenesis
BVB96_00695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVB96_00720	COG0201	protein transport
BVB96_00730	COG0024	Methionine aminopeptidase
BVB96_00740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVB96_00770	COG1122	ATPase activity
BVB96_00775	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVB96_00780	COG0101	tRNA pseudouridine synthase activity
BVB96_00800	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVB96_00805	COG0489	protein tyrosine kinase activity
BVB96_00815	COG2194	sulfuric ester hydrolase activity
BVB96_00820	COG0726	polysaccharide deacetylase
BVB96_00910	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BVB96_00915	COG4856	YbbR-like protein
BVB96_00930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVB96_00935	COG0596	Alpha beta hydrolase
BVB96_00955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BVB96_00960	COG0823	Involved in the tonB-independent uptake of proteins
BVB96_00960	COG1506	peptidase
BVB96_00960	COG4946	Tricorn protease homolog
BVB96_00995	COG2011	ABC-type metal ion transport system permease component
BVB96_01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVB96_01005	COG1464	Belongs to the NlpA lipoprotein family
BVB96_01025	COG2271	Major facilitator Superfamily
BVB96_01035	COG2814	Major facilitator Superfamily
BVB96_01050	COG0601	transmembrane transport
BVB96_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVB96_01060	COG0444	Belongs to the ABC transporter superfamily
BVB96_01065	COG4608	Belongs to the ABC transporter superfamily
BVB96_01070	COG4166	transmembrane transport
BVB96_01080	COG2207	Transcriptional regulator
BVB96_01095	COG4166	transmembrane transport
BVB96_01100	COG4166	transmembrane transport
BVB96_01105	COG0656	L-ascorbic acid biosynthetic process
BVB96_01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVB96_01130	COG4149	molybdate abc transporter
BVB96_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVB96_01140	COG1910	domain protein
BVB96_01160	COG0583	DNA-binding transcription factor activity
BVB96_01165	COG0697	spore germination
BVB96_01180	COG0204	Acyl-transferase
BVB96_01195	COG1609	Transcriptional regulator
BVB96_01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_01220	COG0084	hydrolase, TatD family'
BVB96_01225	COG5298	Protein conserved in bacteria
BVB96_01250	COG0488	(ABC) transporter
BVB96_01265	COG0747	negative chemotaxis
BVB96_01270	COG0601	transmembrane transport
BVB96_01280	COG0444	Belongs to the ABC transporter superfamily
BVB96_01285	COG4608	Belongs to the ABC transporter superfamily
BVB96_01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BVB96_01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVB96_01330	COG2814	Major facilitator Superfamily
BVB96_01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVB96_01350	COG4294	response to UV
BVB96_01355	COG0705	Rhomboid family
BVB96_01355	COG0457	Tetratricopeptide repeat
BVB96_01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVB96_01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVB96_01375	COG0864	Transcriptional regulator
BVB96_01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
BVB96_01385	COG2183	response to ionizing radiation
BVB96_01480	COG0802	atpase or kinase
BVB96_01485	COG1214	PFAM Peptidase M22, glycoprotease
BVB96_01490	COG0456	acetyltransferase
BVB96_01495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVB96_01500	COG0488	(ABC) transporter
BVB96_01515	COG1266	CAAX protease self-immunity
BVB96_01535	COG2252	PERMEase
BVB96_01545	COG5002	protein histidine kinase activity
BVB96_01580	COG2226	methyltransferase
BVB96_01625	COG1968	undecaprenyl-diphosphatase activity
BVB96_01640	COG2205	protein histidine kinase activity
BVB96_01645	COG0745	RESPONSE REGULATOR receiver
BVB96_01670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BVB96_01675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVB96_01680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVB96_01690	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVB96_01705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVB96_01715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVB96_01725	COG0151	Belongs to the GarS family
BVB96_01750	COG0210	DNA helicase
BVB96_01760	COG4851	CamS sex pheromone cAM373 precursor
BVB96_01780	COG1335	isochorismatase
BVB96_01790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVB96_01795	COG2011	ABC-type metal ion transport system permease component
BVB96_01800	COG1464	Belongs to the NlpA lipoprotein family
BVB96_01815	COG0003	Pfam Anion-transporting ATPase
BVB96_01820	COG0003	Pfam Anion-transporting ATPase
BVB96_01825	COG1846	Transcriptional regulator
BVB96_01850	COG1597	lipid kinase activity
BVB96_01855	COG0546	phosphoglycolate phosphatase activity
BVB96_01860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVB96_01870	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_01875	COG2076	Multidrug Resistance protein
BVB96_01880	COG2309	aminopeptidase activity
BVB96_01895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_01900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVB96_01905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVB96_01915	COG4807	Protein conserved in bacteria
BVB96_01945	COG1473	amidohydrolase
BVB96_01960	COG0450	alkyl hydroperoxide reductase
BVB96_01965	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BVB96_01975	COG0235	Class ii aldolase
BVB96_01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_01990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_02015	COG0166	Belongs to the GPI family
BVB96_02055	COG5002	protein histidine kinase activity
BVB96_02075	COG3541	Predicted nucleotidyltransferase
BVB96_02080	COG2814	Major facilitator Superfamily
BVB96_02085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVB96_02085	COG0723	plastoquinol--plastocyanin reductase activity
BVB96_02095	COG0765	amino acid transport
BVB96_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVB96_02115	COG0840	transmembrane signaling receptor activity
BVB96_02120	COG0840	transmembrane signaling receptor activity
BVB96_02125	COG0366	Alpha amylase catalytic
BVB96_02130	COG2190	(PTS) system
BVB96_02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_02130	COG1263	PTS System
BVB96_02160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BVB96_02175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVB96_02185	COG1116	anion transmembrane transporter activity
BVB96_02190	COG0488	(ABC) transporter
BVB96_02235	COG2270	Major facilitator Superfamily
BVB96_02265	COG2310	stress, protein
BVB96_02270	COG2310	stress, protein
BVB96_02275	COG2310	stress, protein
BVB96_02280	COG0861	Integral membrane protein TerC family
BVB96_02290	COG3853	Toxic anion resistance protein (TelA)
BVB96_02305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVB96_02315	COG1295	ribonuclease BN
BVB96_02325	COG2217	Heavy metal translocating P-type atpase
BVB96_02330	COG0697	spore germination
BVB96_02350	COG0586	Pfam SNARE associated Golgi protein
BVB96_02365	COG3871	stress protein (general stress protein 26)
BVB96_02370	COG0387	Pfam Sodium calcium exchanger
BVB96_02380	COG0535	radical SAM domain protein
BVB96_02405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BVB96_02410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVB96_02415	COG0582	viral genome integration into host DNA
BVB96_02420	COG1396	sequence-specific DNA binding
BVB96_02440	COG1396	sequence-specific DNA binding
BVB96_02475	COG1484	DNA-dependent DNA replication
BVB96_02580	COG0582	viral genome integration into host DNA
BVB96_02585	COG0582	viral genome integration into host DNA
BVB96_02730	COG0101	tRNA pseudouridine synthase activity
BVB96_02740	COG3829	transcription factor binding
BVB96_02750	COG0833	amino acid
BVB96_02755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVB96_02785	COG2066	Belongs to the glutaminase family
BVB96_02795	COG1263	PTS System
BVB96_02795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_02800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVB96_02815	COG0463	Glycosyl transferase, family 2
BVB96_02830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVB96_02830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVB96_02845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVB96_02865	COG1228	amidohydrolase
BVB96_02870	COG1090	epimerase
BVB96_02900	COG1988	membrane-bound metal-dependent
BVB96_02905	COG1194	a g-specific adenine glycosylase
BVB96_02930	COG1132	(ABC) transporter
BVB96_02935	COG4129	membrane
BVB96_02940	COG0070	glutamate synthase
BVB96_02940	COG0067	glutamate synthase
BVB96_02940	COG0069	glutamate synthase activity
BVB96_02950	COG4555	ABC transporter
BVB96_02970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVB96_02975	COG0735	belongs to the Fur family
BVB96_03095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BVB96_03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVB96_03110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVB96_03120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVB96_03135	COG2766	serine protein kinase
BVB96_03155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVB96_03165	COG1585	Membrane protein implicated in regulation of membrane protease activity
BVB96_03170	COG2268	Band 7 protein
BVB96_03180	COG3290	protein histidine kinase activity
BVB96_03185	COG4565	transcriptional regulatory protein
BVB96_03190	COG2851	Citrate transporter
BVB96_03210	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BVB96_03215	COG3842	ATPase activity
BVB96_03220	COG1175	transmembrane transport
BVB96_03225	COG0395	ABC-type sugar transport system, permease component
BVB96_03235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVB96_03240	COG0745	RESPONSE REGULATOR receiver
BVB96_03245	COG5002	protein histidine kinase activity
BVB96_03255	COG4990	cell redox homeostasis
BVB96_03265	COG3290	protein histidine kinase activity
BVB96_03270	COG4565	transcriptional regulatory protein
BVB96_03275	COG3493	citrate carrier protein
BVB96_03280	COG0281	malic enzyme
BVB96_03295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_03305	COG5002	protein histidine kinase activity
BVB96_03310	COG0745	RESPONSE REGULATOR receiver
BVB96_03320	COG0456	acetyltransferase
BVB96_03320	COG0454	-acetyltransferase
BVB96_03325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVB96_03330	COG3383	formate dehydrogenase (NAD+) activity
BVB96_03335	COG2427	Protein of unknown function (DUF1641)
BVB96_03350	COG0531	amino acid
BVB96_03355	COG0640	Transcriptional regulator
BVB96_03360	COG2217	Heavy metal translocating P-type atpase
BVB96_03365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BVB96_03380	COG3227	Zinc metalloprotease (Elastase)
BVB96_03400	COG2720	vancomycin resistance protein
BVB96_03405	COG1316	TRANSCRIPTIONal
BVB96_03410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_03415	COG0346	lactoylglutathione lyase activity
BVB96_03420	COG1253	flavin adenine dinucleotide binding
BVB96_03425	COG1027	Aspartate ammonia-lyase
BVB96_03430	COG1620	l-lactate permease
BVB96_03445	COG3104	oligopeptide transport
BVB96_03450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_03455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_03460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_03470	COG2226	methyltransferase
BVB96_03475	COG0156	8-amino-7-oxononanoate synthase activity
BVB96_03480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVB96_03490	COG4548	von Willebrand factor, type A
BVB96_03495	COG0714	Associated with various cellular activities
BVB96_03500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVB96_03520	COG0531	amino acid
BVB96_03525	COG2188	Transcriptional regulator
BVB96_03530	COG1263	PTS System
BVB96_03530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_03535	COG0366	Alpha amylase catalytic
BVB96_03550	COG0697	spore germination
BVB96_03560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVB96_03565	COG1115	amino acid carrier protein
BVB96_03570	COG1126	abc transporter atp-binding protein
BVB96_03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVB96_03580	COG0765	amino acid transport
BVB96_03585	COG0765	amino acid transport
BVB96_03590	COG0833	amino acid
BVB96_03615	COG2378	regulation of single-species biofilm formation
BVB96_03620	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVB96_03625	COG5002	protein histidine kinase activity
BVB96_03640	COG0659	secondary active sulfate transmembrane transporter activity
BVB96_03655	COG0747	negative chemotaxis
BVB96_03665	COG0601	transmembrane transport
BVB96_03670	COG4608	Belongs to the ABC transporter superfamily
BVB96_03680	COG2271	Major facilitator Superfamily
BVB96_03685	COG1846	Transcriptional regulator
BVB96_03695	COG1609	Transcriptional regulator
BVB96_03700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVB96_03710	COG1129	ABC transporter
BVB96_03715	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVB96_03720	COG1879	ABC-type sugar transport system periplasmic component
BVB96_03725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVB96_03745	COG1063	alcohol dehydrogenase
BVB96_03760	COG3568	Endonuclease Exonuclease Phosphatase
BVB96_03785	COG1968	undecaprenyl-diphosphatase activity
BVB96_03790	COG0840	transmembrane signaling receptor activity
BVB96_03795	COG3584	3D domain protein
BVB96_03795	COG1388	LysM domain
BVB96_03800	COG1476	TRANSCRIPTIONal
BVB96_03815	COG3104	oligopeptide transport
BVB96_03820	COG1114	Component of the transport system for branched-chain amino acids
BVB96_03835	COG1113	amino acid transport
BVB96_03840	COG2252	PERMEase
BVB96_03865	COG0475	glutathione-regulated potassium exporter activity
BVB96_03865	COG0569	domain protein
BVB96_03880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVB96_03885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVB96_03890	COG0833	amino acid
BVB96_03895	COG4990	cell redox homeostasis
BVB96_03910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVB96_03915	COG0697	spore germination
BVB96_03920	COG0531	amino acid
BVB96_03935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVB96_03940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVB96_03945	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVB96_03945	COG1918	ferrous iron import across plasma membrane
BVB96_03950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVB96_03955	COG0573	inorganic phosphate transmembrane transporter activity
BVB96_03960	COG0581	inorganic phosphate transmembrane transporter activity
BVB96_03970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVB96_04085	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BVB96_04110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVB96_04115	COG1116	anion transmembrane transporter activity
BVB96_04120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVB96_04125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVB96_04130	COG0352	thiamine-phosphate diphosphorylase activity
BVB96_04135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVB96_04140	COG2104	thiamine diphosphate biosynthetic process
BVB96_04150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVB96_04155	COG0351	phosphomethylpyrimidine kinase
BVB96_04200	COG2205	protein histidine kinase activity
BVB96_04205	COG2814	Major facilitator Superfamily
BVB96_04210	COG1846	Transcriptional regulator
BVB96_04225	COG2252	PERMEase
BVB96_04230	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_04235	COG1376	ErfK ybiS ycfS ynhG family protein
BVB96_04245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVB96_04250	COG1621	beta-fructofuranosidase activity
BVB96_04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_04255	COG1263	PTS System
BVB96_04260	COG1609	Transcriptional regulator
BVB96_04270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVB96_04275	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BVB96_04310	COG0778	Nitroreductase
BVB96_04315	COG2719	SpoVR family
BVB96_04345	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVB96_04350	COG1937	Protein conserved in bacteria
BVB96_04355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVB96_04355	COG0425	Belongs to the sulfur carrier protein TusA family
BVB96_04360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_04360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVB96_04365	COG0425	Belongs to the sulfur carrier protein TusA family
BVB96_04380	COG2210	Belongs to the sulfur carrier protein TusA family
BVB96_04385	COG0730	response to heat
BVB96_04395	COG1316	TRANSCRIPTIONal
BVB96_04400	COG0604	alcohol dehydrogenase
BVB96_04405	COG1283	sodium-dependent phosphate transmembrane transporter activity
BVB96_04420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVB96_04420	COG3711	transcriptional antiterminator
BVB96_04425	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVB96_04430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVB96_04450	COG1388	LysM domain
BVB96_04450	COG3584	3D domain protein
BVB96_04455	COG0577	efflux transmembrane transporter activity
BVB96_04460	COG1136	(ABC) transporter
BVB96_04470	COG5522	Integral membrane protein (intg_mem_TP0381)
BVB96_04485	COG1114	Component of the transport system for branched-chain amino acids
BVB96_04490	COG3546	catalase activity
BVB96_04525	COG0586	Pfam SNARE associated Golgi protein
BVB96_04560	COG0531	amino acid
BVB96_04565	COG0475	glutathione-regulated potassium exporter activity
BVB96_04575	COG1737	Transcriptional regulator
BVB96_04585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_04585	COG1263	PTS System
BVB96_04595	COG2259	Doxx family
BVB96_04610	COG0697	spore germination
BVB96_04615	COG1522	sequence-specific DNA binding
BVB96_04625	COG2076	Multidrug Resistance protein
BVB96_04630	COG2076	Multidrug Resistance protein
BVB96_04635	COG1309	transcriptional regulator
BVB96_04640	COG2814	Major facilitator Superfamily
BVB96_04645	COG1733	regulation of RNA biosynthetic process
BVB96_04655	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVB96_04660	COG4533	DNA binding
BVB96_04665	COG2211	Major facilitator Superfamily
BVB96_04675	COG0693	protein deglycase activity
BVB96_04680	COG0753	catalase activity
BVB96_04680	COG0693	protein deglycase activity
BVB96_04690	COG0531	amino acid
BVB96_04695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVB96_04705	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_04725	COG1132	(ABC) transporter
BVB96_04740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVB96_04745	COG0765	amino acid transport
BVB96_04750	COG1126	abc transporter atp-binding protein
BVB96_04765	COG0189	ligase activity
BVB96_04795	COG0028	Belongs to the TPP enzyme family
BVB96_04800	COG3527	Alpha-acetolactate decarboxylase
BVB96_04815	COG0561	phosphatase activity
BVB96_04825	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVB96_04825	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_04835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVB96_04855	COG0659	secondary active sulfate transmembrane transporter activity
BVB96_04875	COG0653	protein targeting
BVB96_04880	COG2244	polysaccharide biosynthetic process
BVB96_04890	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVB96_04895	COG4196	transglutaminase domain protein
BVB96_04910	COG1696	Membrane protein involved in D-alanine export
BVB96_04930	COG1024	Enoyl-CoA hydratase
BVB96_04950	COG1363	Peptidase, m42
BVB96_04970	COG3938	Belongs to the proline racemase family
BVB96_05015	COG0601	transmembrane transport
BVB96_05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVB96_05025	COG0444	Belongs to the ABC transporter superfamily
BVB96_05030	COG0444	Belongs to the ABC transporter superfamily
BVB96_05035	COG4608	Belongs to the ABC transporter superfamily
BVB96_05045	COG0322	excinuclease ABC activity
BVB96_05080	COG0477	Major facilitator Superfamily
BVB96_05085	COG3290	protein histidine kinase activity
BVB96_05090	COG4565	transcriptional regulatory protein
BVB96_05095	COG3181	Tripartite tricarboxylate transporter family receptor
BVB96_05125	COG0789	Transcriptional regulator
BVB96_05125	COG4978	Transcriptional regulator
BVB96_05140	COG0305	Participates in initiation and elongation during chromosome replication
BVB96_05190	COG0477	Major facilitator Superfamily
BVB96_05265	COG1183	phosphatidylcholine synthase activity
BVB96_05285	COG2376	Dihydroxyacetone kinase
BVB96_05295	COG2376	Dihydroxyacetone kinase
BVB96_05300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVB96_05305	COG1959	2 iron, 2 sulfur cluster binding
BVB96_05340	COG3437	response regulator, receiver
BVB96_05340	COG2770	Histidine kinase
BVB96_05405	COG3237	CsbD-like
BVB96_05430	COG1191	sigma factor activity
BVB96_05440	COG2208	phosphoserine phosphatase activity
BVB96_05445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVB96_05450	COG2198	Histidine kinase
BVB96_05450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVB96_05450	COG2205	protein histidine kinase activity
BVB96_05450	COG0784	Response regulator, receiver
BVB96_05510	COG0420	3'-5' exonuclease activity
BVB96_05515	COG4717	serine-type aminopeptidase activity
BVB96_05535	COG1309	transcriptional regulator
BVB96_05540	COG2814	Major facilitator Superfamily
BVB96_05545	COG0346	lactoylglutathione lyase activity
BVB96_05550	COG0346	lactoylglutathione lyase activity
BVB96_05555	COG0457	Tetratricopeptide repeat
BVB96_05565	COG2267	carboxylic ester hydrolase activity
BVB96_05585	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BVB96_05590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVB96_05600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BVB96_05645	COG0477	Major facilitator Superfamily
BVB96_05650	COG0477	Major facilitator Superfamily
BVB96_05660	COG3973	AAA domain
BVB96_05665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVB96_05685	COG4980	gas vesicle protein
BVB96_05690	COG0537	adenosine 5'-monophosphoramidase activity
BVB96_05695	COG1131	(ABC) transporter
BVB96_05700	COG4473	ABC transporter
BVB96_05715	COG1309	transcriptional regulator
BVB96_05725	COG3402	PFAM membrane-flanked domain
BVB96_05770	COG3402	PFAM membrane-flanked domain
BVB96_05775	COG3428	Bacterial PH domain
BVB96_05780	COG2329	Antibiotic biosynthesis monooxygenase
BVB96_05785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVB96_05790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BVB96_05835	COG1309	transcriptional regulator
BVB96_05840	COG1511	domain protein
BVB96_05865	COG1609	Transcriptional regulator
BVB96_05875	COG1234	tRNA 3'-trailer cleavage
BVB96_05880	COG0095	Lipoate-protein ligase
BVB96_05895	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_05925	COG3209	COG3209 Rhs family protein
BVB96_05980	COG1408	metallophosphoesterase
BVB96_05985	COG1078	dGTPase activity
BVB96_05995	COG1595	DNA-templated transcription, initiation
BVB96_06000	COG2207	Transcriptional regulator
BVB96_06000	COG3708	Transcriptional regulator
BVB96_06015	COG2205	protein histidine kinase activity
BVB96_06020	COG0745	RESPONSE REGULATOR receiver
BVB96_06045	COG0501	Belongs to the peptidase M48B family
BVB96_06050	COG0840	transmembrane signaling receptor activity
BVB96_06055	COG0697	spore germination
BVB96_06070	COG0497	DNA recombination
BVB96_06075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVB96_06080	COG2224	Isocitrate lyase
BVB96_06090	COG1278	Cold shock
BVB96_06105	COG4903	ComK protein
BVB96_06110	COG0398	Pfam SNARE associated Golgi protein
BVB96_06120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BVB96_06125	COG1074	ATP-dependent DNA helicase activity
BVB96_06170	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVB96_06195	COG0367	asparagine synthase
BVB96_06205	COG0753	catalase activity
BVB96_06210	COG0004	ammonium transporteR
BVB96_06235	COG2996	Protein conserved in bacteria
BVB96_06245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVB96_06255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_06270	COG0561	phosphatase activity
BVB96_06280	COG0542	response to heat
BVB96_06290	COG2267	carboxylic ester hydrolase activity
BVB96_06310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_06315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVB96_06320	COG5504	Zn-dependent protease
BVB96_06330	COG0180	Tryptophanyl-tRNA synthetase
BVB96_06345	COG4166	transmembrane transport
BVB96_06350	COG0601	transmembrane transport
BVB96_06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVB96_06360	COG0444	Belongs to the ABC transporter superfamily
BVB96_06365	COG4608	Belongs to the ABC transporter superfamily
BVB96_06370	COG0534	Mate efflux family protein
BVB96_06375	COG4166	transmembrane transport
BVB96_06385	COG1393	Belongs to the ArsC family
BVB96_06390	COG0861	Integral membrane protein TerC family
BVB96_06395	COG4862	establishment of competence for transformation
BVB96_06400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVB96_06410	COG1164	Oligoendopeptidase f
BVB96_06425	COG2346	COG2346, Truncated hemoglobins
BVB96_06430	COG4116	CYTH
BVB96_06440	COG2357	RelA SpoT domain protein
BVB96_06445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVB96_06450	COG0564	pseudouridine synthase activity
BVB96_06470	COG1216	Glycosyl transferase, family 2
BVB96_06510	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BVB96_06525	COG1091	dTDP-4-dehydrorhamnose reductase activity
BVB96_06570	COG2153	protein acetylation
BVB96_06575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BVB96_06580	COG2382	esterase
BVB96_06595	COG5492	domain, Protein
BVB96_06600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVB96_06615	COG0512	Glutamine amidotransferase of anthranilate synthase
BVB96_06615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVB96_06650	COG1620	l-lactate permease
BVB96_06655	COG5634	Uncharacterized conserved protein (DUF2278)
BVB96_06710	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVB96_06720	COG1476	TRANSCRIPTIONal
BVB96_06780	COG2226	methyltransferase
BVB96_06795	COG1686	Belongs to the peptidase S11 family
BVB96_06800	COG0681	Belongs to the peptidase S26 family
BVB96_06835	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_06840	COG3842	ATPase activity
BVB96_06845	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVB96_06850	COG1177	transmembrane transport
BVB96_06855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVB96_06865	COG2409	Drug exporters of the RND superfamily
BVB96_06875	COG0564	pseudouridine synthase activity
BVB96_06885	COG2340	Cysteine-rich secretory protein family
BVB96_06890	COG0247	lactate metabolic process
BVB96_06895	COG0277	FAD linked oxidase domain protein
BVB96_06900	COG3835	regulator
BVB96_06910	COG0745	RESPONSE REGULATOR receiver
BVB96_06915	COG5002	protein histidine kinase activity
BVB96_06920	COG2186	Transcriptional regulator
BVB96_06940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BVB96_06950	COG2116	formate transmembrane transporter activity
BVB96_06955	COG0861	Integral membrane protein TerC family
BVB96_06970	COG2030	dehydratase
BVB96_06990	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_06995	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVB96_07005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVB96_07025	COG1840	ABC-type Fe3 transport system, periplasmic component
BVB96_07040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVB96_07055	COG1349	DNA-binding transcription factor activity
BVB96_07075	COG0235	Class ii aldolase
BVB96_07090	COG2861	carbohydrate metabolic process
BVB96_07100	COG3852	Histidine kinase
BVB96_07105	COG1846	Transcriptional regulator
BVB96_07115	COG2318	DinB family
BVB96_07125	COG5002	protein histidine kinase activity
BVB96_07135	COG0720	synthase
BVB96_07150	COG4873	Protein conserved in bacteria
BVB96_07185	COG1780	Probably involved in ribonucleotide reductase function
BVB96_07190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVB96_07200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVB96_07205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVB96_07210	COG1725	Transcriptional regulator
BVB96_07215	COG1131	(ABC) transporter
BVB96_07225	COG1131	(ABC) transporter
BVB96_07230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVB96_07245	COG1522	sequence-specific DNA binding
BVB96_07255	COG1335	isochorismatase
BVB96_07265	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVB96_07270	COG2070	2-Nitropropane dioxygenase
BVB96_07275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BVB96_07285	COG1696	Membrane protein involved in D-alanine export
BVB96_07310	COG0716	FMN binding
BVB96_07325	COG3173	Aminoglycoside phosphotransferase
BVB96_07350	COG0534	Mate efflux family protein
BVB96_07355	COG1968	undecaprenyl-diphosphatase activity
BVB96_07370	COG1846	Transcriptional regulator
BVB96_07380	COG1301	dicarboxylic acid transport
BVB96_07390	COG4709	membrane
BVB96_07395	COG3874	Sporulation protein YtfJ
BVB96_07425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVB96_07430	COG0028	Belongs to the TPP enzyme family
BVB96_07435	COG0440	acetolactate synthase activity
BVB96_07440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVB96_07450	COG0473	3-isopropylmalate dehydrogenase activity
BVB96_07475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVB96_07510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVB96_07525	COG1183	phosphatidylcholine synthase activity
BVB96_07530	COG1368	sulfuric ester hydrolase activity
BVB96_07540	COG0019	diaminopimelate decarboxylase activity
BVB96_07560	COG0529	Catalyzes the synthesis of activated sulfate
BVB96_07565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVB96_07585	COG1648	precorrin-2 dehydrogenase activity
BVB96_07590	COG0733	neurotransmitter:sodium symporter activity
BVB96_07610	COG1757	Na H antiporter
BVB96_07625	COG4758	membrane
BVB96_07630	COG4585	Histidine kinase
BVB96_07635	COG2197	response regulator
BVB96_07645	COG1114	Component of the transport system for branched-chain amino acids
BVB96_07655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVB96_07680	COG1017	nitric oxide dioxygenase activity
BVB96_07680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVB96_07695	COG0730	response to heat
BVB96_07700	COG0306	phosphate transporter
BVB96_07705	COG1392	Phosphate transport regulator
BVB96_07710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVB96_07730	COG1801	Protein of unknown function DUF72
BVB96_07740	COG0582	viral genome integration into host DNA
BVB96_07745	COG5002	protein histidine kinase activity
BVB96_07775	COG0392	lysyltransferase activity
BVB96_07775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BVB96_07790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVB96_07795	COG1686	Belongs to the peptidase S11 family
BVB96_07800	COG2715	membrane protein required for spore maturation
BVB96_07805	COG0700	Nucleoside recognition
BVB96_07810	COG1187	pseudouridine synthase activity
BVB96_07820	COG1333	cytochrome c biogenesis protein
BVB96_07825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVB96_07830	COG0745	RESPONSE REGULATOR receiver
BVB96_07835	COG5002	protein histidine kinase activity
BVB96_07840	COG2096	Adenosyltransferase
BVB96_07855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BVB96_07860	COG1141	Ferredoxin
BVB96_07865	COG4955	Helix-turn-helix domain
BVB96_07870	COG0514	ATP-dependent DNA helicase (RecQ)
BVB96_07875	COG1266	CAAX protease self-immunity
BVB96_07895	COG4862	establishment of competence for transformation
BVB96_07900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVB96_07920	COG0492	ferredoxin-NADP+ reductase activity
BVB96_07995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVB96_08010	COG0142	geranyltranstransferase activity
BVB96_08020	COG0142	geranyltranstransferase activity
BVB96_08025	COG0105	UTP biosynthetic process
BVB96_08040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVB96_08045	COG0457	Tetratricopeptide repeat
BVB96_08065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVB96_08080	COG4347	Protein of unknown function (DUF1405)
BVB96_08095	COG2738	Putative neutral zinc metallopeptidase
BVB96_08105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_08115	COG1694	Mazg nucleotide pyrophosphohydrolase
BVB96_08130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVB96_08135	COG0438	transferase activity, transferring glycosyl groups
BVB96_08195	COG3935	DnaD domain protein
BVB96_08200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVB96_08210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVB96_08210	COG4499	WXG100 protein secretion system (Wss), protein YukC
BVB96_08260	COG4474	Belongs to the UPF0398 family
BVB96_08275	COG0116	Belongs to the methyltransferase superfamily
BVB96_08285	COG1199	ATP-dependent helicase activity
BVB96_08290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BVB96_08300	COG3173	Aminoglycoside phosphotransferase
BVB96_08305	COG0024	Methionine aminopeptidase
BVB96_08315	COG2233	PERMEase
BVB96_08320	COG2311	Membrane
BVB96_08330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVB96_08340	COG0456	acetyltransferase
BVB96_08390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVB96_08415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVB96_08430	COG1215	transferase activity, transferring glycosyl groups
BVB96_08455	COG0454	-acetyltransferase
BVB96_08475	COG0328	RNA-DNA hybrid ribonuclease activity
BVB96_08515	COG1280	lysine exporter protein (LysE YggA)
BVB96_08530	COG3162	membrane
BVB96_08535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVB96_08540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVB96_08555	COG0475	glutathione-regulated potassium exporter activity
BVB96_08560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BVB96_08565	COG4978	Transcriptional regulator
BVB96_08565	COG0789	Transcriptional regulator
BVB96_08575	COG2323	membrane
BVB96_08580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BVB96_08635	COG1923	regulation of RNA biosynthetic process
BVB96_08645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVB96_08650	COG1360	Flagellar Motor Protein
BVB96_08655	COG2201	protein-glutamate methylesterase activity
BVB96_08660	COG0643	Histidine kinase
BVB96_08660	COG2198	Histidine kinase
BVB96_08665	COG2198	Histidine kinase
BVB96_08665	COG0643	Histidine kinase
BVB96_08670	COG1776	CheC inhibitor of MCP methylation
BVB96_08670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVB96_08685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVB96_08705	COG1256	bacterial-type flagellum assembly
BVB96_08735	COG1815	bacterial-type flagellum-dependent cell motility
BVB96_08740	COG1558	bacterial-type flagellum-dependent cell motility
BVB96_08745	COG1677	Flagellar hook-basal body complex protein FliE
BVB96_08755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVB96_08765	COG1157	protein secretion by the type III secretion system
BVB96_08810	COG0784	Response regulator, receiver
BVB96_08810	COG0835	chemotaxis
BVB96_08820	COG0463	Glycosyl transferase, family 2
BVB96_08880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVB96_08885	COG0741	lytic transglycosylase activity
BVB96_08895	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVB96_08905	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVB96_08905	COG1776	CheC inhibitor of MCP methylation
BVB96_08915	COG1338	Plays a role in the flagellum-specific transport system
BVB96_08920	COG1987	bacterial-type flagellum assembly
BVB96_08930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVB96_08935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVB96_08940	COG1419	protein localization to endoplasmic reticulum
BVB96_08945	COG4786	Flagellar basal body rod
BVB96_08950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVB96_08975	COG1309	transcriptional regulator
BVB96_08995	COG2329	Antibiotic biosynthesis monooxygenase
BVB96_09025	COG3842	ATPase activity
BVB96_09030	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVB96_09035	COG1177	transmembrane transport
BVB96_09040	COG1234	tRNA 3'-trailer cleavage
BVB96_09070	COG1686	Belongs to the peptidase S11 family
BVB96_09080	COG0406	alpha-ribazole phosphatase activity
BVB96_09110	COG0367	asparagine synthase
BVB96_09140	COG1802	Transcriptional regulator
BVB96_09145	COG0697	spore germination
BVB96_09150	COG0523	cobalamin synthesis protein
BVB96_09160	COG0701	Predicted permease
BVB96_09170	COG0438	transferase activity, transferring glycosyl groups
BVB96_09170	COG1216	Glycosyl transferase, family 2
BVB96_09175	COG1757	Na H antiporter
BVB96_09180	COG0114	fumarate hydratase activity
BVB96_09210	COG3340	Belongs to the peptidase S51 family
BVB96_09230	COG0785	Cytochrome C biogenesis protein
BVB96_09265	COG2733	membrane
BVB96_09305	COG1131	(ABC) transporter
BVB96_09320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVB96_09325	COG0528	UMP kinase activity
BVB96_09335	COG1027	Aspartate ammonia-lyase
BVB96_09340	COG0281	malic enzyme
BVB96_09345	COG4191	Histidine kinase
BVB96_09350	COG0784	Response regulator, receiver
BVB96_09355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVB96_09425	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVB96_09450	COG1966	Carbon starvation protein
BVB96_09465	COG0477	Major facilitator Superfamily
BVB96_09470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_09480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVB96_09495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVB96_09510	COG2244	polysaccharide biosynthetic process
BVB96_09515	COG0733	neurotransmitter:sodium symporter activity
BVB96_09525	COG5566	PFAM Mor transcription activator
BVB96_09530	COG2323	membrane
BVB96_09550	COG2084	Dehydrogenase
BVB96_09570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVB96_09580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVB96_09585	COG0028	Belongs to the TPP enzyme family
BVB96_09590	COG0440	acetolactate synthase activity
BVB96_09595	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVB96_09605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVB96_09640	COG3384	dioxygenase
BVB96_09650	COG3279	Response regulator of the LytR AlgR family
BVB96_09655	COG0427	acetyl-CoA hydrolase
BVB96_09675	COG1073	alpha beta
BVB96_09680	COG1131	(ABC) transporter
BVB96_09685	COG4166	transmembrane transport
BVB96_09720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_09740	COG1914	H( )-stimulated, divalent metal cation uptake system
BVB96_09755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVB96_09785	COG2390	Transcriptional regulator
BVB96_09795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_09800	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BVB96_09810	COG4846	Membrane protein involved in cytochrome C biogenesis
BVB96_09815	COG4224	UPF0291 protein
BVB96_09835	COG0006	proline dipeptidase activity
BVB96_09840	COG2132	Multicopper oxidase
BVB96_09870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVB96_09885	COG1276	copper resistance
BVB96_09885	COG2372	response to copper ion
BVB96_09890	COG4549	nuclear export factor GLE1
BVB96_09900	COG0697	spore germination
BVB96_09905	COG0583	DNA-binding transcription factor activity
BVB96_09910	COG1959	2 iron, 2 sulfur cluster binding
BVB96_09915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BVB96_09920	COG0778	Nitroreductase
BVB96_09935	COG0628	permease
BVB96_09940	COG0039	L-malate dehydrogenase activity
BVB96_09945	COG1231	oxidoreductase activity
BVB96_09950	COG0523	cobalamin synthesis protein
BVB96_09965	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_09970	COG2030	dehydratase
BVB96_09975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_09990	COG0411	ABC transporter
BVB96_10010	COG0583	DNA-binding transcription factor activity
BVB96_10020	COG1942	4-Oxalocrotonate Tautomerase
BVB96_10030	COG1846	Transcriptional regulator
BVB96_10040	COG1271	oxidase subunit
BVB96_10045	COG1294	oxidase, subunit
BVB96_10050	COG4988	ABC transporter
BVB96_10055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BVB96_10075	COG1686	Belongs to the peptidase S11 family
BVB96_10090	COG0791	NLP P60 protein
BVB96_10090	COG1388	LysM domain
BVB96_10100	COG1132	(ABC) transporter
BVB96_10105	COG1132	(ABC) transporter
BVB96_10110	COG0745	RESPONSE REGULATOR receiver
BVB96_10125	COG0300	oxidoreductase activity
BVB96_10140	COG0726	polysaccharide deacetylase
BVB96_10170	COG0460	homoserine dehydrogenase
BVB96_10195	COG1316	TRANSCRIPTIONal
BVB96_10205	COG0745	RESPONSE REGULATOR receiver
BVB96_10210	COG5002	protein histidine kinase activity
BVB96_10215	COG0726	polysaccharide deacetylase
BVB96_10225	COG1285	pathogenesis
BVB96_10230	COG1247	-acetyltransferase
BVB96_10240	COG4264	IucA IucC family
BVB96_10245	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_10260	COG1082	Xylose isomerase domain protein TIM barrel
BVB96_10270	COG2814	Major facilitator Superfamily
BVB96_10275	COG1279	arginine transmembrane transporter activity
BVB96_10290	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVB96_10325	COG0577	efflux transmembrane transporter activity
BVB96_10330	COG2002	toxin-antitoxin pair type II binding
BVB96_10335	COG1404	Belongs to the peptidase S8 family
BVB96_10340	COG0640	Transcriptional regulator
BVB96_10345	COG0667	Aldo Keto reductase
BVB96_10375	COG0840	transmembrane signaling receptor activity
BVB96_10390	COG3949	Membrane
BVB96_10395	COG0783	Belongs to the Dps family
BVB96_10410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVB96_10420	COG1231	oxidoreductase activity
BVB96_10430	COG4989	oxidoreductase activity
BVB96_10435	COG0523	cobalamin synthesis protein
BVB96_10440	COG0456	acetyltransferase
BVB96_10515	COG3443	Belongs to the bacterial solute-binding protein 9 family
BVB96_10515	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVB96_10525	COG0702	epimerase
BVB96_10535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVB96_10545	COG4166	transmembrane transport
BVB96_10560	COG0406	alpha-ribazole phosphatase activity
BVB96_10570	COG5337	Spore coat protein CotH
BVB96_10575	COG1051	belongs to the nudix hydrolase family
BVB96_10580	COG0586	Pfam SNARE associated Golgi protein
BVB96_10585	COG2244	polysaccharide biosynthetic process
BVB96_10595	COG0701	Predicted permease
BVB96_10600	COG3689	TIGRFAM TIGR03943 family protein
BVB96_10605	COG1607	acyl-coa hydrolase
BVB96_10615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVB96_10630	COG0702	epimerase
BVB96_10635	COG2839	Protein conserved in bacteria
BVB96_10640	COG1253	flavin adenine dinucleotide binding
BVB96_10655	COG1114	Component of the transport system for branched-chain amino acids
BVB96_10660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_10680	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVB96_10690	COG1876	peptidase activity
BVB96_10700	COG0154	amidase activity
BVB96_10705	COG2211	Major facilitator Superfamily
BVB96_10725	COG0561	phosphatase activity
BVB96_10735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVB96_10755	COG1819	glycosyl
BVB96_10760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_10795	COG0456	acetyltransferase
BVB96_10855	COG3874	Sporulation protein YtfJ
BVB96_10880	COG2226	methyltransferase
BVB96_10900	COG1082	Xylose isomerase domain protein TIM barrel
BVB96_10905	COG0346	lactoylglutathione lyase activity
BVB96_10915	COG0604	alcohol dehydrogenase
BVB96_10920	COG1595	DNA-templated transcription, initiation
BVB96_10945	COG0386	Belongs to the glutathione peroxidase family
BVB96_10950	COG1305	Transglutaminase-like
BVB96_10955	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BVB96_10960	COG0714	Associated with various cellular activities
BVB96_10975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BVB96_10980	COG1140	nitrate reductase beta subunit
BVB96_10985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BVB96_10990	COG2181	nitrate reductase activity
BVB96_11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVB96_11015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVB96_11020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVB96_11025	COG0303	'Molybdopterin
BVB96_11030	COG0314	molybdopterin synthase activity
BVB96_11040	COG2223	nitrite transmembrane transporter activity
BVB96_11060	COG1648	precorrin-2 dehydrogenase activity
BVB96_11070	COG1587	Uroporphyrinogen-III synthase
BVB96_11070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVB96_11075	COG2146	nitrite reductase [NAD(P)H] activity
BVB96_11080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVB96_11085	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BVB96_11120	COG2359	stage V sporulation protein S
BVB96_11140	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVB96_11155	COG1418	mRNA catabolic process
BVB96_11160	COG0488	(ABC) transporter
BVB96_11175	COG0629	single-stranded DNA binding
BVB96_11190	COG1413	lyase activity
BVB96_11205	COG2136	Putative SAM-dependent methyltransferase
BVB96_11205	COG2521	methyltransferase
BVB96_11210	COG0018	arginyl-trna synthetase
BVB96_11240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVB96_11260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVB96_11265	COG0017	Asparaginyl-tRNA synthetase
BVB96_11285	COG1674	ftsk spoiiie
BVB96_11385	COG1929	Belongs to the glycerate kinase type-1 family
BVB96_11390	COG0471	metal ion transport
BVB96_11395	COG0745	RESPONSE REGULATOR receiver
BVB96_11400	COG3850	Histidine kinase
BVB96_11400	COG5002	protein histidine kinase activity
BVB96_11415	COG0733	neurotransmitter:sodium symporter activity
BVB96_11440	COG2610	gluconate transmembrane transporter activity
BVB96_11445	COG1454	alcohol dehydrogenase
BVB96_11450	COG1794	racemase activity, acting on amino acids and derivatives
BVB96_11460	COG0456	acetyltransferase
BVB96_11475	COG1131	(ABC) transporter
BVB96_11490	COG0546	phosphoglycolate phosphatase activity
BVB96_11510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVB96_11525	COG0768	penicillin binding
BVB96_11530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVB96_11535	COG0204	Acyl-transferase
BVB96_11540	COG1272	protein, Hemolysin III
BVB96_11550	COG0805	protein transport
BVB96_11565	COG1307	EDD domain protein, DegV family
BVB96_11570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BVB96_11575	COG1999	signal sequence binding
BVB96_11580	COG0071	Belongs to the small heat shock protein (HSP20) family
BVB96_11585	COG0367	asparagine synthase
BVB96_11605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_11610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVB96_11635	COG1051	belongs to the nudix hydrolase family
BVB96_11645	COG0668	transmembrane transport
BVB96_11650	COG2203	Gaf domain
BVB96_11650	COG4585	Histidine kinase
BVB96_11655	COG2197	response regulator
BVB96_11665	COG1737	Transcriptional regulator
BVB96_11670	COG1064	alcohol dehydrogenase
BVB96_11700	COG1070	Carbohydrate kinase
BVB96_11735	COG1125	glycine betaine transport
BVB96_11735	COG0517	IMP dehydrogenase activity
BVB96_11740	COG1174	glycine betaine transport
BVB96_11775	COG1253	flavin adenine dinucleotide binding
BVB96_11780	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_11785	COG5506	Protein of unknown function (DUF1694)
BVB96_11805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVB96_11810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVB96_11815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVB96_11820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVB96_11825	COG0456	acetyltransferase
BVB96_11830	COG3829	transcription factor binding
BVB96_11840	COG1509	lysine 2,3-aminomutase activity
BVB96_11880	COG4326	sporulation control protein
BVB96_11885	COG0671	phosphoesterase, PA-phosphatase related
BVB96_11890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVB96_11895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVB96_11925	COG1787	Restriction endonuclease
BVB96_11925	COG1715	Restriction endonuclease
BVB96_12035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVB96_12075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVB96_12075	COG4499	WXG100 protein secretion system (Wss), protein YukC
BVB96_12080	COG2814	Major facilitator Superfamily
BVB96_12085	COG4841	protein insertion into membrane
BVB96_12090	COG0372	Belongs to the citrate synthase family
BVB96_12095	COG2079	MmgE PrpD family protein
BVB96_12100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BVB96_12105	COG1960	acyl-CoA dehydrogenase activity
BVB96_12110	COG2084	Dehydrogenase
BVB96_12115	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_12120	COG1280	lysine exporter protein (LysE YggA)
BVB96_12125	COG1024	Enoyl-CoA hydratase
BVB96_12140	COG0420	3'-5' exonuclease activity
BVB96_12145	COG0419	ATPase involved in DNA repair
BVB96_12180	COG2223	nitrite transmembrane transporter activity
BVB96_12190	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_12195	COG1169	isochorismate synthase
BVB96_12200	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVB96_12205	COG3433	isochorismatase activity
BVB96_12205	COG1535	isochorismatase
BVB96_12215	COG3251	PFAM MbtH domain protein
BVB96_12220	COG2814	Major facilitator Superfamily
BVB96_12235	COG0776	regulation of translation
BVB96_12245	COG2318	DinB family
BVB96_12270	COG2329	Antibiotic biosynthesis monooxygenase
BVB96_12275	COG1187	pseudouridine synthase activity
BVB96_12280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVB96_12285	COG1136	(ABC) transporter
BVB96_12305	COG0596	Alpha beta hydrolase
BVB96_12310	COG2814	Major facilitator Superfamily
BVB96_12335	COG2226	methyltransferase
BVB96_12380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_12415	COG1247	-acetyltransferase
BVB96_12455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_12465	COG1278	Cold shock
BVB96_12480	COG0010	Belongs to the arginase family
BVB96_12485	COG0561	phosphatase activity
BVB96_12530	COG0583	DNA-binding transcription factor activity
BVB96_12535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVB96_12550	COG0583	DNA-binding transcription factor activity
BVB96_12555	COG2258	MOSC domain
BVB96_12570	COG1132	(ABC) transporter
BVB96_12575	COG1132	(ABC) transporter
BVB96_12595	COG1396	sequence-specific DNA binding
BVB96_12625	COG1595	DNA-templated transcription, initiation
BVB96_12655	COG1649	PFAM Uncharacterised BCR, COG1649
BVB96_12685	COG2971	BadF BadG BcrA BcrD
BVB96_12690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVB96_12695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVB96_12715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_12745	COG1309	transcriptional regulator
BVB96_12760	COG0577	efflux transmembrane transporter activity
BVB96_12760	COG1136	(ABC) transporter
BVB96_12765	COG0500	methyltransferase
BVB96_12765	COG3615	Tellurite resistance protein tehB
BVB96_12775	COG2226	methyltransferase
BVB96_12780	COG3961	Belongs to the TPP enzyme family
BVB96_12785	COG1846	Transcriptional regulator
BVB96_12835	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVB96_12855	COG1595	DNA-templated transcription, initiation
BVB96_12865	COG0768	penicillin binding
BVB96_12875	COG2367	Beta-lactamase
BVB96_12885	COG1609	Transcriptional regulator
BVB96_12895	COG0673	inositol 2-dehydrogenase activity
BVB96_12905	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_12940	COG0737	Belongs to the 5'-nucleotidase family
BVB96_12950	COG0457	Tetratricopeptide repeat
BVB96_12955	COG1476	TRANSCRIPTIONal
BVB96_12975	COG1876	peptidase activity
BVB96_12995	COG1309	transcriptional regulator
BVB96_13015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_13035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVB96_13050	COG1131	(ABC) transporter
BVB96_13060	COG1309	transcriptional regulator
BVB96_13080	COG1960	acyl-CoA dehydrogenase activity
BVB96_13085	COG0439	Biotin carboxylase
BVB96_13090	COG0511	ligase activity, forming carbon-carbon bonds
BVB96_13095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVB96_13100	COG1024	Enoyl-CoA hydratase
BVB96_13105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVB96_13110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVB96_13120	COG1247	-acetyltransferase
BVB96_13125	COG0572	uridine kinase
BVB96_13135	COG2318	DinB family
BVB96_13140	COG1686	Belongs to the peptidase S11 family
BVB96_13165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVB96_13205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVB96_13205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVB96_13220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVB96_13230	COG2814	Major facilitator Superfamily
BVB96_13250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVB96_13270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_13285	COG1063	alcohol dehydrogenase
BVB96_13315	COG3773	Cell wall hydrolase
BVB96_13330	COG0745	RESPONSE REGULATOR receiver
BVB96_13360	COG1136	(ABC) transporter
BVB96_13385	COG0460	homoserine dehydrogenase
BVB96_13390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_13400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVB96_13500	COG2124	cytochrome p450
BVB96_13535	COG0561	phosphatase activity
BVB96_13545	COG5002	protein histidine kinase activity
BVB96_13555	COG1819	glycosyl
BVB96_13560	COG1794	racemase activity, acting on amino acids and derivatives
BVB96_13570	COG1122	ATPase activity
BVB96_13585	COG2205	protein histidine kinase activity
BVB96_13600	COG0604	alcohol dehydrogenase
BVB96_13615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVB96_13650	COG0693	protein deglycase activity
BVB96_13685	COG2814	Major facilitator Superfamily
BVB96_13705	COG0584	glycerophosphoryl diester phosphodiesterase
BVB96_13725	COG0697	spore germination
BVB96_13730	COG0697	spore germination
BVB96_13770	COG2223	nitrite transmembrane transporter activity
BVB96_13785	COG2816	NAD+ diphosphatase activity
BVB96_13790	COG0592	DNA-directed DNA polymerase activity
BVB96_13795	COG1051	belongs to the nudix hydrolase family
BVB96_13830	COG3878	Protein conserved in bacteria
BVB96_13880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVB96_13895	COG0322	excinuclease ABC activity
BVB96_13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVB96_13965	COG1011	Hydrolase
BVB96_13985	COG0076	glutamate decarboxylase activity
BVB96_14000	COG1523	belongs to the glycosyl hydrolase 13 family
BVB96_14005	COG3227	Zinc metalloprotease (Elastase)
BVB96_14025	COG0201	protein transport
BVB96_14035	COG0697	spore germination
BVB96_14040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_14070	COG4129	membrane
BVB96_14075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_14090	COG2959	enzyme of heme biosynthesis
BVB96_14095	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_14095	COG3773	Cell wall hydrolase
BVB96_14110	COG3483	tryptophan 2,3-dioxygenase activity
BVB96_14115	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BVB96_14120	COG3844	kynureninase activity
BVB96_14125	COG1309	transcriptional regulator
BVB96_14160	COG3284	Transcriptional regulator
BVB96_14180	COG1349	DNA-binding transcription factor activity
BVB96_14205	COG1959	2 iron, 2 sulfur cluster binding
BVB96_14225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVB96_14230	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVB96_14235	COG0022	dehydrogenase e1 component
BVB96_14240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVB96_14250	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_14255	COG0456	acetyltransferase
BVB96_14255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVB96_14290	COG4176	ABC-type proline glycine betaine transport system permease component
BVB96_14295	COG4175	Glycine betaine
BVB96_14295	COG0517	IMP dehydrogenase activity
BVB96_14305	COG0740	serine-type endopeptidase activity
BVB96_14320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVB96_14325	COG2153	protein acetylation
BVB96_14330	COG3397	chitin binding
BVB96_14345	COG2205	protein histidine kinase activity
BVB96_14375	COG2333	competence protein COMEC
BVB96_14375	COG0658	competence protein
BVB96_14425	COG3973	AAA domain
BVB96_14440	COG2105	PFAM AIG2 family protein
BVB96_14445	COG0514	ATP-dependent DNA helicase (RecQ)
BVB96_14470	COG4637	Psort location Cytoplasmic, score
BVB96_14495	COG3397	chitin binding
BVB96_14505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVB96_14510	COG1115	amino acid carrier protein
BVB96_14515	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_14520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVB96_14530	COG3938	Belongs to the proline racemase family
BVB96_14535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVB96_14575	COG0586	Pfam SNARE associated Golgi protein
BVB96_14590	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BVB96_14595	COG0519	Catalyzes the synthesis of GMP from XMP
BVB96_14600	COG4166	transmembrane transport
BVB96_14610	COG4948	Mandelate Racemase Muconate Lactonizing
BVB96_14660	COG2936	dipeptidyl-peptidase activity
BVB96_14665	COG5002	protein histidine kinase activity
BVB96_14670	COG0745	RESPONSE REGULATOR receiver
BVB96_14705	COG1164	Oligoendopeptidase f
BVB96_14720	COG1307	EDD domain protein, DegV family
BVB96_14745	COG2814	Major facilitator Superfamily
BVB96_14755	COG1664	Polymer-forming cytoskeletal
BVB96_14760	COG0789	Transcriptional regulator
BVB96_14765	COG4533	DNA binding
BVB96_14770	COG2814	Major facilitator Superfamily
BVB96_14770	COG0477	Major facilitator Superfamily
BVB96_14790	COG2261	transglycosylase associated protein
BVB96_14805	COG2226	methyltransferase
BVB96_14850	COG0436	Aminotransferase
BVB96_14855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVB96_14860	COG5146	pantothenate kinase activity
BVB96_14880	COG1131	(ABC) transporter
BVB96_14930	COG0628	permease
BVB96_14945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVB96_14950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVB96_14955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVB96_14960	COG1116	anion transmembrane transporter activity
BVB96_15000	COG2746	aminoglycoside 3-N-acetyltransferase activity
BVB96_15030	COG0697	spore germination
BVB96_15035	COG2318	DinB family
BVB96_15055	COG4912	Dna alkylation repair
BVB96_15070	COG0726	polysaccharide deacetylase
BVB96_15080	COG0861	Integral membrane protein TerC family
BVB96_15085	COG1368	sulfuric ester hydrolase activity
BVB96_15095	COG0488	(ABC) transporter
BVB96_15110	COG1309	transcriptional regulator
BVB96_15125	COG0287	Prephenate dehydrogenase
BVB96_15130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVB96_15135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVB96_15145	COG1605	Chorismate mutase
BVB96_15145	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BVB96_15195	COG3584	3D domain protein
BVB96_15195	COG1388	LysM domain
BVB96_15210	COG1595	DNA-templated transcription, initiation
BVB96_15235	COG1879	ABC-type sugar transport system periplasmic component
BVB96_15245	COG1172	Belongs to the binding-protein-dependent transport system permease family
BVB96_15255	COG2390	Transcriptional regulator
BVB96_15260	COG1070	Carbohydrate kinase
BVB96_15290	COG2329	Antibiotic biosynthesis monooxygenase
BVB96_15310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_15320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVB96_15325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVB96_15330	COG4187	Peptidase family M20/M25/M40
BVB96_15335	COG1414	Transcriptional regulator
BVB96_15340	COG0833	amino acid
BVB96_15345	COG1690	Belongs to the RtcB family
BVB96_15350	COG3239	Fatty acid desaturase
BVB96_15355	COG1785	Belongs to the alkaline phosphatase family
BVB96_15365	COG3655	Transcriptional regulator
BVB96_15380	COG4377	Putative membrane peptidase family (DUF2324)
BVB96_15390	COG3279	Response regulator of the LytR AlgR family
BVB96_15400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_15405	COG0346	lactoylglutathione lyase activity
BVB96_15425	COG0714	Associated with various cellular activities
BVB96_15450	COG0463	Glycosyl transferase, family 2
BVB96_15475	COG0463	Glycosyl transferase, family 2
BVB96_15485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVB96_15490	COG0753	catalase activity
BVB96_15500	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BVB96_15530	COG0714	Associated with various cellular activities
BVB96_15540	COG0778	Nitroreductase
BVB96_15545	COG1846	Transcriptional regulator
BVB96_15585	COG1725	Transcriptional regulator
BVB96_15600	COG0577	efflux transmembrane transporter activity
BVB96_15600	COG1136	(ABC) transporter
BVB96_15625	COG2207	Transcriptional regulator
BVB96_15630	COG0456	acetyltransferase
BVB96_15650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_15670	COG0642	Histidine kinase
BVB96_15675	COG0745	RESPONSE REGULATOR receiver
BVB96_15680	COG0596	Alpha beta hydrolase
BVB96_15710	COG0730	response to heat
BVB96_15720	COG0833	amino acid
BVB96_15730	COG4335	DNA alkylation repair
BVB96_15780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVB96_15815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BVB96_15820	COG1414	Transcriptional regulator
BVB96_15840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVB96_15845	COG0640	Transcriptional regulator
BVB96_15855	COG1960	acyl-CoA dehydrogenase activity
BVB96_15890	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BVB96_15905	COG0574	Belongs to the PEP-utilizing enzyme family
BVB96_15905	COG3848	Pyruvate phosphate dikinase
BVB96_15915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_15930	COG5577	PFAM Coat F domain
BVB96_15940	COG3403	YqcI/YcgG family
BVB96_15945	COG1280	lysine exporter protein (LysE YggA)
BVB96_15980	COG1063	alcohol dehydrogenase
BVB96_15995	COG1027	Aspartate ammonia-lyase
BVB96_16000	COG0252	asparaginase activity
BVB96_16005	COG1396	sequence-specific DNA binding
BVB96_16015	COG0322	excinuclease ABC activity
BVB96_16020	COG0531	amino acid
BVB96_16025	COG1114	Component of the transport system for branched-chain amino acids
BVB96_16030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVB96_16040	COG0281	malic enzyme
BVB96_16055	COG0531	amino acid
BVB96_16070	COG0784	Response regulator, receiver
BVB96_16075	COG4191	Histidine kinase
BVB96_16080	COG4191	Histidine kinase
BVB96_16085	COG2066	Belongs to the glutaminase family
BVB96_16090	COG1115	amino acid carrier protein
BVB96_16120	COG0737	Belongs to the 5'-nucleotidase family
BVB96_16125	COG0753	catalase activity
BVB96_16130	COG2267	carboxylic ester hydrolase activity
BVB96_16135	COG1335	isochorismatase
BVB96_16155	COG0583	DNA-binding transcription factor activity
BVB96_16165	COG1846	Transcriptional regulator
BVB96_16170	COG0598	Magnesium transport protein CorA
BVB96_16210	COG0415	Belongs to the DNA photolyase family
BVB96_16215	COG0288	reversible hydration of carbon dioxide
BVB96_16225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVB96_16230	COG5609	conserved protein (DUF2294)
BVB96_16245	COG1575	Belongs to the MenA family. Type 1 subfamily
BVB96_16250	COG2267	carboxylic ester hydrolase activity
BVB96_16260	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVB96_16265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVB96_16270	COG1121	(ABC) transporter
BVB96_16300	COG0798	PFAM Bile acid sodium symporter
BVB96_16305	COG0346	lactoylglutathione lyase activity
BVB96_16310	COG0640	Transcriptional regulator
BVB96_16325	COG0443	Heat shock 70 kDa protein
BVB96_16340	COG1522	sequence-specific DNA binding
BVB96_16360	COG0346	lactoylglutathione lyase activity
BVB96_16380	COG2169	Transcriptional regulator
BVB96_16430	COG2814	Major facilitator Superfamily
BVB96_16460	COG0745	RESPONSE REGULATOR receiver
BVB96_16465	COG3850	Histidine kinase
BVB96_16465	COG5002	protein histidine kinase activity
BVB96_16490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVB96_16520	COG1476	TRANSCRIPTIONal
BVB96_16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_16540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVB96_16550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_16555	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BVB96_16570	COG1136	(ABC) transporter
BVB96_16575	COG0577	efflux transmembrane transporter activity
BVB96_16595	COG3850	Histidine kinase
BVB96_16595	COG5002	protein histidine kinase activity
BVB96_16605	COG2364	Membrane
BVB96_16610	COG1846	Transcriptional regulator
BVB96_16615	COG0456	acetyltransferase
BVB96_16620	COG0456	acetyltransferase
BVB96_16625	COG2808	Putative FMN-binding domain
BVB96_16630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_16635	COG2271	Major facilitator Superfamily
BVB96_16640	COG1556	Lactate utilization protein
BVB96_16645	COG1139	Iron-sulfur cluster binding protein
BVB96_16655	COG0583	DNA-binding transcription factor activity
BVB96_16665	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVB96_16700	COG0673	inositol 2-dehydrogenase activity
BVB96_16705	COG0561	phosphatase activity
BVB96_16710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVB96_16715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVB96_16720	COG1609	Transcriptional regulator
BVB96_16725	COG0457	Tetratricopeptide repeat
BVB96_16745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVB96_16775	COG0534	Mate efflux family protein
BVB96_16800	COG2184	nucleotidyltransferase activity
BVB96_16805	COG2814	Major facilitator Superfamily
BVB96_16810	COG1309	transcriptional regulator
BVB96_16825	COG0814	amino acid
BVB96_16830	COG1760	l-serine dehydratase
BVB96_16850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVB96_16855	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BVB96_16870	COG1522	sequence-specific DNA binding
BVB96_16875	COG0531	amino acid
BVB96_16895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVB96_16915	COG1595	DNA-templated transcription, initiation
BVB96_16930	COG0662	Cupin 2, conserved barrel domain protein
BVB96_16940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_16940	COG2207	Transcriptional regulator
BVB96_16990	COG0477	Major facilitator Superfamily
BVB96_17000	COG1846	Transcriptional regulator
BVB96_17005	COG2814	Major facilitator Superfamily
BVB96_17020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVB96_17025	COG1131	(ABC) transporter
BVB96_17045	COG2076	Multidrug Resistance protein
BVB96_17050	COG1309	transcriptional regulator
BVB96_17065	COG2031	fatty acid transporter
BVB96_17075	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVB96_17105	COG1122	ATPase activity
BVB96_17110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVB96_17125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVB96_17130	COG1288	antiporter activity
BVB96_17135	COG2356	endonuclease I
BVB96_17150	COG3620	sequence-specific DNA binding
BVB96_17155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVB96_17160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVB96_17165	COG0124	histidyl-tRNA synthetase
BVB96_17180	COG1733	regulation of RNA biosynthetic process
BVB96_17185	COG0778	Nitroreductase
BVB96_17210	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_17220	COG1131	(ABC) transporter
BVB96_17245	COG1011	Hydrolase
BVB96_17280	COG0346	lactoylglutathione lyase activity
BVB96_17285	COG1940	carbohydrate kinase activity
BVB96_17290	COG0738	Major facilitator superfamily
BVB96_17295	COG0110	maltose O-acetyltransferase activity
BVB96_17305	COG1136	(ABC) transporter
BVB96_17315	COG0180	Tryptophanyl-tRNA synthetase
BVB96_17320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVB96_17325	COG0628	permease
BVB96_17345	COG2226	methyltransferase
BVB96_17355	COG0477	Major facilitator Superfamily
BVB96_17385	COG1253	flavin adenine dinucleotide binding
BVB96_17390	COG0789	Transcriptional regulator
BVB96_17395	COG0697	spore germination
BVB96_17400	COG1357	PFAM Pentapeptide repeats (8 copies)
BVB96_17405	COG3813	Protein conserved in bacteria
BVB96_17410	COG2706	6-phosphogluconolactonase activity
BVB96_17415	COG1070	Carbohydrate kinase
BVB96_17425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVB96_17430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BVB96_17440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVB96_17445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVB96_17450	COG0604	alcohol dehydrogenase
BVB96_17455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVB96_17475	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_17500	COG0656	L-ascorbic acid biosynthetic process
BVB96_17505	COG2814	Major facilitator Superfamily
BVB96_17520	COG0346	lactoylglutathione lyase activity
BVB96_17525	COG0814	amino acid
BVB96_17550	COG1393	Belongs to the ArsC family
BVB96_17560	COG1733	regulation of RNA biosynthetic process
BVB96_17565	COG2188	Transcriptional regulator
BVB96_17570	COG0673	inositol 2-dehydrogenase activity
BVB96_17575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVB96_17580	COG1733	regulation of RNA biosynthetic process
BVB96_17585	COG1733	regulation of RNA biosynthetic process
BVB96_17600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_17620	COG0384	phenazine biosynthesis protein PhzF
BVB96_17630	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_17640	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_17650	COG1733	regulation of RNA biosynthetic process
BVB96_17675	COG0726	polysaccharide deacetylase
BVB96_17690	COG1191	sigma factor activity
BVB96_17705	COG1309	transcriptional regulator
BVB96_17725	COG3152	Membrane
BVB96_17755	COG1151	hydroxylamine reductase activity
BVB96_17770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_17775	COG3757	hydrolase, family 25
BVB96_17775	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_17810	COG2072	flavoprotein involved in K transport
BVB96_17845	COG0604	alcohol dehydrogenase
BVB96_17850	COG1113	amino acid transport
BVB96_17855	COG2814	Major facilitator Superfamily
BVB96_17890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVB96_17895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVB96_17915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_17935	COG3739	integral membrane protein
BVB96_17940	COG0384	phenazine biosynthesis protein PhzF
BVB96_17970	COG0583	DNA-binding transcription factor activity
BVB96_17990	COG1193	negative regulation of DNA recombination
BVB96_18005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BVB96_18010	COG1164	Oligoendopeptidase f
BVB96_18015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BVB96_18045	COG0584	glycerophosphoryl diester phosphodiesterase
BVB96_18070	COG0640	Transcriptional regulator
BVB96_18075	COG0604	alcohol dehydrogenase
BVB96_18095	COG2808	Putative FMN-binding domain
BVB96_18110	COG0385	Bile acid
BVB96_18115	COG0277	FAD linked oxidase domain protein
BVB96_18155	COG1216	Glycosyl transferase, family 2
BVB96_18160	COG1024	Enoyl-CoA hydratase
BVB96_18170	COG1285	pathogenesis
BVB96_18185	COG2514	catechol 2,3-dioxygenase activity
BVB96_18190	COG2720	vancomycin resistance protein
BVB96_18220	COG1278	Cold shock
BVB96_18230	COG0716	FMN binding
BVB96_18260	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_18285	COG4145	pantothenate transmembrane transporter activity
BVB96_18295	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_18300	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_18310	COG1657	PFAM Prenyltransferase squalene oxidase
BVB96_18315	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BVB96_18320	COG2962	Rard protein
BVB96_18325	COG3326	Membrane
BVB96_18340	COG0489	protein tyrosine kinase activity
BVB96_18350	COG0314	molybdopterin synthase activity
BVB96_18355	COG0303	'Molybdopterin
BVB96_18360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVB96_18365	COG2116	formate transmembrane transporter activity
BVB96_18380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVB96_18385	COG5609	conserved protein (DUF2294)
BVB96_18390	COG2427	Protein of unknown function (DUF1641)
BVB96_18395	COG3383	formate dehydrogenase (NAD+) activity
BVB96_18405	COG0697	spore germination
BVB96_18445	COG2226	methyltransferase
BVB96_18450	COG4166	transmembrane transport
BVB96_18455	COG4166	transmembrane transport
BVB96_18460	COG4166	transmembrane transport
BVB96_18465	COG1301	dicarboxylic acid transport
BVB96_18470	COG1316	TRANSCRIPTIONal
BVB96_18480	COG1595	DNA-templated transcription, initiation
BVB96_18505	COG1131	(ABC) transporter
BVB96_18515	COG0673	inositol 2-dehydrogenase activity
BVB96_18520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVB96_18525	COG0187	DNA topoisomerase II activity
BVB96_18535	COG1832	CoA-binding protein
BVB96_18540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVB96_18545	COG0745	RESPONSE REGULATOR receiver
BVB96_18560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVB96_18565	COG4841	protein insertion into membrane
BVB96_18570	COG0824	Thioesterase
BVB96_18605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVB96_18615	COG2274	protein secretion by the type I secretion system
BVB96_18620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVB96_18630	COG0726	polysaccharide deacetylase
BVB96_18650	COG2211	Major facilitator Superfamily
BVB96_18660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVB96_18675	COG0183	Belongs to the thiolase family
BVB96_18680	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_18685	COG1268	BioY protein
BVB96_18690	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_18745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_18760	COG5002	protein histidine kinase activity
BVB96_18765	COG0400	carboxylic ester hydrolase activity
BVB96_18770	COG0346	lactoylglutathione lyase activity
BVB96_18775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVB96_18780	COG0069	glutamate synthase activity
BVB96_18785	COG1902	pentaerythritol trinitrate reductase activity
BVB96_18790	COG1329	Transcriptional regulator
BVB96_18795	COG0010	Belongs to the arginase family
BVB96_18820	COG2226	methyltransferase
BVB96_18880	COG4846	Membrane protein involved in cytochrome C biogenesis
BVB96_18885	COG0785	Cytochrome C biogenesis protein
BVB96_18900	COG0583	DNA-binding transcription factor activity
BVB96_18905	COG1380	Effector of murein hydrolase LrgA
BVB96_18910	COG1346	cytolysis
BVB96_18935	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_18935	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVB96_18950	COG1132	(ABC) transporter
BVB96_18955	COG1132	(ABC) transporter
BVB96_18995	COG3639	organic phosphonate transmembrane transporter activity
BVB96_19000	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BVB96_19020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BVB96_19040	COG1695	Transcriptional regulator
BVB96_19085	COG5632	N-Acetylmuramoyl-L-alanine amidase
BVB96_19085	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_19085	COG1388	LysM domain
BVB96_19090	COG4824	toxin secretion phage lysis holin
BVB96_19240	COG1595	DNA-templated transcription, initiation
BVB96_19285	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BVB96_19375	COG1396	sequence-specific DNA binding
BVB96_19400	COG0174	glutamine synthetase
BVB96_19405	COG0789	Transcriptional regulator
BVB96_19410	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BVB96_19415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVB96_19420	COG2860	membrane
BVB96_19425	COG0464	growth
BVB96_19455	COG1388	LysM domain
BVB96_19455	COG3584	3D domain protein
BVB96_19460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVB96_19460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVB96_19460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVB96_19465	COG1105	Belongs to the carbohydrate kinase PfkB family
BVB96_19470	COG1349	DNA-binding transcription factor activity
BVB96_19480	COG2322	membrane
BVB96_19495	COG1113	amino acid transport
BVB96_19520	COG1408	metallophosphoesterase
BVB96_19525	COG2116	formate transmembrane transporter activity
BVB96_19535	COG2217	Heavy metal translocating P-type atpase
BVB96_19540	COG2608	mercury ion transmembrane transporter activity
BVB96_19545	COG1937	Protein conserved in bacteria
BVB96_19555	COG2819	hydrolase of the alpha beta superfamily
BVB96_19560	COG1120	ATPase activity
BVB96_19565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_19570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_19575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_19590	COG2169	Transcriptional regulator
BVB96_19595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVB96_19600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BVB96_19610	COG2364	Membrane
BVB96_19630	COG0346	lactoylglutathione lyase activity
BVB96_19635	COG5001	Diguanylate cyclase
BVB96_19635	COG3300	MHYT domain
BVB96_19655	COG1346	cytolysis
BVB96_19660	COG1380	Effector of murein hydrolase LrgA
BVB96_19665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVB96_19670	COG0596	Alpha beta hydrolase
BVB96_19670	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVB96_19675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BVB96_19695	COG1404	Belongs to the peptidase S8 family
BVB96_19700	COG3773	Cell wall hydrolase
BVB96_19705	COG0562	UDP-galactopyranose mutase
BVB96_19710	COG1368	sulfuric ester hydrolase activity
BVB96_19715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVB96_19725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BVB96_19770	COG4550	Control of competence regulator ComK, YlbF/YmcA
BVB96_19775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVB96_19780	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVB96_19785	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVB96_19785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVB96_19795	COG2359	stage V sporulation protein S
BVB96_19800	COG1692	metallophosphoesterase
BVB96_19825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVB96_19830	COG1426	Protein conserved in bacteria
BVB96_19845	COG0300	oxidoreductase activity
BVB96_19850	COG0612	Peptidase, M16
BVB96_19855	COG0612	Peptidase, M16
BVB96_19885	COG2188	Transcriptional regulator
BVB96_19890	COG1674	ftsk spoiiie
BVB96_19900	COG0740	serine-type endopeptidase activity
BVB96_19905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BVB96_19920	COG0527	aspartate kinase activity
BVB96_19925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVB96_19930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVB96_19935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVB96_19945	COG1873	PFAM PRC-barrel domain
BVB96_19950	COG0612	Peptidase, M16
BVB96_19955	COG0726	polysaccharide deacetylase
BVB96_19970	COG0196	riboflavin kinase activity
BVB96_19975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVB96_19985	COG1550	Protein conserved in bacteria
BVB96_19995	COG1358	cellular component organization or biogenesis
BVB96_20000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BVB96_20005	COG0195	Participates in both transcription termination and antitermination
BVB96_20030	COG0750	zinc metalloprotease
BVB96_20035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVB96_20040	COG4589	Belongs to the CDS family
BVB96_20055	COG0528	UMP kinase activity
BVB96_20085	COG4974	Belongs to the 'phage' integrase family
BVB96_20095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVB96_20105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BVB96_20145	COG1837	Belongs to the UPF0109 family
BVB96_20155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVB96_20165	COG0552	protein localization to endoplasmic reticulum
BVB96_20170	COG1196	nuclear chromosome segregation
BVB96_20185	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_20190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVB96_20205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVB96_20210	COG1461	Dihydroxyacetone kinase
BVB96_20215	COG1302	Protein conserved in bacteria
BVB96_20230	COG1564	THIamine pyrophosphokinase
BVB96_20235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVB96_20240	COG1162	GTPase activity
BVB96_20245	COG2815	serine threonine protein kinase
BVB96_20245	COG0515	serine threonine protein kinase
BVB96_20250	COG0631	protein serine/threonine phosphatase activity
BVB96_20260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVB96_20260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVB96_20270	COG0242	peptide deformylase activity
BVB96_20275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVB96_20280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVB96_20290	COG0194	GDP metabolic process
BVB96_20300	COG1561	YicC-like family, N-terminal region
BVB96_20305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVB96_20315	COG0006	proline dipeptidase activity
BVB96_20335	COG3069	C4-dicarboxylate transmembrane transporter activity
BVB96_20375	COG0505	Belongs to the CarA family
BVB96_20400	COG0564	pseudouridine synthase activity
BVB96_20415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVB96_20420	COG3599	regulation of cell shape
BVB96_20425	COG2302	S4 RNA-binding domain
BVB96_20430	COG0762	integral membrane protein
BVB96_20440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVB96_20450	COG1873	PFAM PRC-barrel domain
BVB96_20455	COG1191	sigma factor activity
BVB96_20460	COG1191	sigma factor activity
BVB96_20470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVB96_20475	COG0849	cell division
BVB96_20480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVB96_20485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVB96_20490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVB96_20495	COG0772	Belongs to the SEDS family
BVB96_20510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVB96_20515	COG0768	penicillin binding
BVB96_20525	COG4839	cell division protein FtsL
BVB96_20540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVB96_20545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVB96_20565	COG1399	metal-binding, possibly nucleic acid-binding protein
BVB96_20615	COG4824	toxin secretion phage lysis holin
BVB96_20705	COG4626	Terminase
BVB96_20705	COG1802	Transcriptional regulator
BVB96_20735	COG0582	viral genome integration into host DNA
BVB96_20825	COG1191	sigma factor activity
BVB96_20850	COG1484	DNA-dependent DNA replication
BVB96_20875	COG1396	sequence-specific DNA binding
BVB96_20890	COG1396	sequence-specific DNA binding
BVB96_20910	COG0582	viral genome integration into host DNA
BVB96_20920	COG3480	Lon protease (S16) C-terminal proteolytic domain
BVB96_20925	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVB96_20930	COG3314	Sporulation integral membrane protein YlbJ
BVB96_20940	COG0742	ribosomal rna small subunit methyltransferase
BVB96_20955	COG3679	Belongs to the UPF0342 family
BVB96_20960	COG0406	alpha-ribazole phosphatase activity
BVB96_20975	COG2340	Cysteine-rich secretory protein family
BVB96_20990	COG3336	cytochrome c oxidase
BVB96_21025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BVB96_21035	COG0772	Belongs to the SEDS family
BVB96_21040	COG4838	Belongs to the UPF0358 family
BVB96_21045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVB96_21050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BVB96_21060	COG4896	Protein conserved in bacteria
BVB96_21085	COG0483	inositol monophosphate 1-phosphatase activity
BVB96_21105	COG1982	Orn Lys Arg decarboxylase major
BVB96_21155	COG0022	dehydrogenase e1 component
BVB96_21160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVB96_21170	COG0242	peptide deformylase activity
BVB96_21175	COG0561	phosphatase activity
BVB96_21190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BVB96_21195	COG0569	domain protein
BVB96_21215	COG0583	DNA-binding transcription factor activity
BVB96_21220	COG0517	IMP dehydrogenase activity
BVB96_21230	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BVB96_21240	COG4703	Protein of unknown function (DUF1797)
BVB96_21255	COG2200	EAL domain
BVB96_21260	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_21265	COG1408	metallophosphoesterase
BVB96_21320	COG2814	Major facilitator Superfamily
BVB96_21340	COG3209	COG3209 Rhs family protein
BVB96_21355	COG2205	protein histidine kinase activity
BVB96_21365	COG0436	Aminotransferase
BVB96_21370	COG1609	Transcriptional regulator
BVB96_21375	COG3833	ABC-type maltose transport systems, permease component
BVB96_21380	COG1175	transmembrane transport
BVB96_21385	COG2182	Extracellular solute-binding protein
BVB96_21395	COG0366	Alpha amylase catalytic
BVB96_21400	COG3842	ATPase activity
BVB96_21440	COG0183	Belongs to the thiolase family
BVB96_21480	COG1695	Transcriptional regulator
BVB96_21485	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_21505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVB96_21510	COG0436	Aminotransferase
BVB96_21530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BVB96_21555	COG3706	GGDEF domain
BVB96_21560	COG0778	Nitroreductase
BVB96_21585	COG1263	PTS System
BVB96_21585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVB96_21585	COG2190	(PTS) system
BVB96_21590	COG3711	transcriptional antiterminator
BVB96_21610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BVB96_21640	COG1547	Domain of unknown function (DUF309)
BVB96_21645	COG0456	acetyltransferase
BVB96_21655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVB96_21660	COG4086	secreted protein
BVB96_21665	COG0561	phosphatase activity
BVB96_21670	COG0697	spore germination
BVB96_21685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_21710	COG0733	neurotransmitter:sodium symporter activity
BVB96_21730	COG1686	Belongs to the peptidase S11 family
BVB96_21740	COG1725	Transcriptional regulator
BVB96_21745	COG1131	(ABC) transporter
BVB96_21765	COG1846	Transcriptional regulator
BVB96_21780	COG0598	Magnesium transport protein CorA
BVB96_21805	COG4974	Belongs to the 'phage' integrase family
BVB96_21815	COG0735	belongs to the Fur family
BVB96_21820	COG1300	Membrane
BVB96_21840	COG0667	Aldo Keto reductase
BVB96_21845	COG0656	L-ascorbic acid biosynthetic process
BVB96_21850	COG0456	acetyltransferase
BVB96_21850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVB96_21860	COG4085	toxin activity
BVB96_21860	COG1525	nuclease
BVB96_21860	COG0737	Belongs to the 5'-nucleotidase family
BVB96_21870	COG0596	Alpha beta hydrolase
BVB96_21875	COG2056	Na+-H+ antiporter family
BVB96_21880	COG1609	Transcriptional regulator
BVB96_21885	COG0456	acetyltransferase
BVB96_21890	COG1073	alpha beta
BVB96_21905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVB96_21905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVB96_21910	COG0307	riboflavin synthase, alpha
BVB96_21930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVB96_21935	COG4106	trans-aconitate 2-methyltransferase activity
BVB96_21940	COG1073	alpha beta
BVB96_21940	COG2226	methyltransferase
BVB96_21945	COG0156	8-amino-7-oxononanoate synthase activity
BVB96_21955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVB96_21975	COG0737	Belongs to the 5'-nucleotidase family
BVB96_21985	COG1522	sequence-specific DNA binding
BVB96_22005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVB96_22015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVB96_22030	COG0300	oxidoreductase activity
BVB96_22035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_22040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVB96_22045	COG1760	l-serine dehydratase
BVB96_22050	COG1760	l-serine dehydratase
BVB96_22075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVB96_22085	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVB96_22090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_22105	COG1376	ErfK ybiS ycfS ynhG family protein
BVB96_22110	COG4129	membrane
BVB96_22115	COG1126	abc transporter atp-binding protein
BVB96_22120	COG0765	amino acid transport
BVB96_22125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVB96_22145	COG2816	NAD+ diphosphatase activity
BVB96_22150	COG0772	Belongs to the SEDS family
BVB96_22155	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVB96_22160	COG0022	dehydrogenase e1 component
BVB96_22165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVB96_22170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVB96_22180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVB96_22185	COG0280	phosphate acetyltransferase
BVB96_22195	COG3290	protein histidine kinase activity
BVB96_22195	COG3829	transcription factor binding
BVB96_22205	COG0584	glycerophosphoryl diester phosphodiesterase
BVB96_22210	COG3093	addiction module antidote protein HigA
BVB96_22220	COG0745	RESPONSE REGULATOR receiver
BVB96_22230	COG0750	zinc metalloprotease
BVB96_22235	COG0497	DNA recombination
BVB96_22245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BVB96_22255	COG0142	geranyltranstransferase activity
BVB96_22280	COG1302	Protein conserved in bacteria
BVB96_22285	COG0439	Biotin carboxylase
BVB96_22290	COG0511	ligase activity, forming carbon-carbon bonds
BVB96_22335	COG3854	ATPases associated with a variety of cellular activities
BVB96_22360	COG0006	proline dipeptidase activity
BVB96_22375	COG3872	metal-dependent enzyme
BVB96_22385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVB96_22405	COG0095	Lipoate-protein ligase
BVB96_22410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVB96_22415	COG1609	Transcriptional regulator
BVB96_22425	COG2076	Multidrug Resistance protein
BVB96_22430	COG2076	Multidrug Resistance protein
BVB96_22470	COG1131	(ABC) transporter
BVB96_22475	COG1725	Transcriptional regulator
BVB96_22510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVB96_22570	COG4970	Tfp pilus assembly protein FimT
BVB96_22580	COG1459	type II secretion system
BVB96_22585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVB96_22635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVB96_22645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVB96_22645	COG0646	methionine synthase
BVB96_22650	COG0626	cystathionine gamma-synthase activity
BVB96_22655	COG0626	cystathionine gamma-synthase activity
BVB96_22675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_22685	COG1940	carbohydrate kinase activity
BVB96_22690	COG4483	Protein conserved in bacteria
BVB96_22695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVB96_22705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVB96_22710	COG0704	Plays a role in the regulation of phosphate uptake
BVB96_22715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVB96_22720	COG0581	inorganic phosphate transmembrane transporter activity
BVB96_22725	COG0573	inorganic phosphate transmembrane transporter activity
BVB96_22730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVB96_22740	COG0477	Major facilitator Superfamily
BVB96_22745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVB96_22770	COG0735	belongs to the Fur family
BVB96_22775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVB96_22780	COG1121	(ABC) transporter
BVB96_22785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_22815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVB96_22820	COG2384	SAM-dependent methyltransferase
BVB96_22825	COG2010	Cytochrome c
BVB96_22830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVB96_22835	COG0358	DNA primase activity
BVB96_22855	COG0517	IMP dehydrogenase activity
BVB96_22870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVB96_22875	COG0295	cytidine deaminase activity
BVB96_22880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVB96_22890	COG1480	7TM receptor with intracellular HD hydrolase
BVB96_22895	COG1702	phosphate starvation-inducible protein PhoH
BVB96_22915	COG1610	YqeY-like protein
BVB96_22930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVB96_22935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVB96_22955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVB96_22965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVB96_22970	COG1733	regulation of RNA biosynthetic process
BVB96_22995	COG1466	dna polymerase III delta subunit
BVB96_23005	COG2333	competence protein COMEC
BVB96_23005	COG0658	competence protein
BVB96_23010	COG2131	deaminase
BVB96_23015	COG1555	photosystem II stabilization
BVB96_23015	COG1596	polysaccharide export
BVB96_23020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVB96_23025	COG2226	methyltransferase
BVB96_23030	COG0799	negative regulation of ribosome biogenesis
BVB96_23035	COG1713	HD superfamily hydrolase involved in NAD metabolism
BVB96_23045	COG1534	Rna-binding protein
BVB96_23055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BVB96_23060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BVB96_23075	COG1191	sigma factor activity
BVB96_23085	COG1595	DNA-templated transcription, initiation
BVB96_23095	COG0778	Nitroreductase
BVB96_23100	COG2357	RelA SpoT domain protein
BVB96_23110	COG1785	Belongs to the alkaline phosphatase family
BVB96_23120	COG2267	carboxylic ester hydrolase activity
BVB96_23155	COG1404	Belongs to the peptidase S8 family
BVB96_23160	COG3186	Phenylalanine-4-hydroxylase
BVB96_23170	COG2514	catechol 2,3-dioxygenase activity
BVB96_23175	COG2259	Doxx family
BVB96_23215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_23230	COG1012	belongs to the aldehyde dehydrogenase family
BVB96_23230	COG1454	alcohol dehydrogenase
BVB96_23235	COG0626	cystathionine gamma-synthase activity
BVB96_23240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVB96_23265	COG0768	penicillin binding
BVB96_23295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVB96_23315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVB96_23325	COG0628	permease
BVB96_23345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVB96_23355	COG0482	sulfurtransferase activity
BVB96_23360	COG1104	cysteine desulfurase activity
BVB96_23365	COG1959	2 iron, 2 sulfur cluster binding
BVB96_23370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVB96_23380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVB96_23390	COG0124	histidyl-tRNA synthetase
BVB96_23410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVB96_23420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVB96_23420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BVB96_23425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVB96_23430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVB96_23430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVB96_23440	COG2244	polysaccharide biosynthetic process
BVB96_23445	COG2323	membrane
BVB96_23455	COG1862	Preprotein translocase
BVB96_23485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BVB96_23495	COG0697	spore germination
BVB96_23500	COG0697	spore germination
BVB96_23505	COG0640	Transcriptional regulator
BVB96_23530	COG0157	Belongs to the NadC ModD family
BVB96_23535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVB96_23540	COG1104	cysteine desulfurase activity
BVB96_23545	COG1827	regulation of RNA biosynthetic process
BVB96_23550	COG2258	MOSC domain
BVB96_23555	COG0077	Prephenate dehydratase
BVB96_23560	COG0577	efflux transmembrane transporter activity
BVB96_23565	COG0577	efflux transmembrane transporter activity
BVB96_23570	COG1136	(ABC) transporter
BVB96_23580	COG0745	RESPONSE REGULATOR receiver
BVB96_23585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVB96_23590	COG3290	protein histidine kinase activity
BVB96_23600	COG2868	ribosomal protein
BVB96_23610	COG1530	ribonuclease E activity
BVB96_23615	COG1994	Peptidase M50
BVB96_23620	COG0739	heme binding
BVB96_23625	COG2894	cell division
BVB96_23640	COG1792	Involved in formation and maintenance of cell shape
BVB96_23645	COG1077	Cell shape determining protein MreB Mrl
BVB96_23670	COG0285	dihydrofolate synthase activity
BVB96_23675	COG0525	valine-tRNA ligase activity
BVB96_23685	COG1388	LysM domain
BVB96_23695	COG0113	porphobilinogen synthase activity
BVB96_23700	COG1587	Uroporphyrinogen-III synthase
BVB96_23710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVB96_23720	COG1846	Transcriptional regulator
BVB96_23725	COG1764	response to oxidative stress
BVB96_23740	COG1067	ATP-dependent peptidase activity
BVB96_23740	COG0470	DNA polymerase III
BVB96_23795	COG0622	Phosphoesterase
BVB96_23800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVB96_23810	COG5401	PFAM Sporulation and spore germination
BVB96_23830	COG1309	transcriptional regulator
BVB96_23845	COG2197	response regulator
BVB96_23850	COG2233	PERMEase
BVB96_23860	COG0402	S-adenosylhomocysteine deaminase activity
BVB96_23865	COG0402	S-adenosylhomocysteine deaminase activity
BVB96_23885	COG0444	Belongs to the ABC transporter superfamily
BVB96_23890	COG4608	Belongs to the ABC transporter superfamily
BVB96_23900	COG3279	Response regulator of the LytR AlgR family
BVB96_23915	COG1983	PspC domain protein
BVB96_23920	COG1396	sequence-specific DNA binding
BVB96_23925	COG0697	spore germination
BVB96_23935	COG1959	2 iron, 2 sulfur cluster binding
BVB96_23940	COG1668	transmembrane transport
BVB96_23945	COG4152	abc transporter atp-binding protein
BVB96_23950	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BVB96_23955	COG1360	Flagellar Motor Protein
BVB96_23960	COG1360	Flagellar Motor Protein
BVB96_23965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVB96_23970	COG1876	peptidase activity
BVB96_23975	COG0824	Thioesterase
BVB96_23980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVB96_23985	COG1053	succinate dehydrogenase
BVB96_23990	COG2009	succinate dehydrogenase
BVB96_23995	COG1719	4-vinyl reductase, 4VR
BVB96_24005	COG3118	belongs to the thioredoxin family
BVB96_24010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVB96_24015	COG2086	electron transfer activity
BVB96_24020	COG1024	Enoyl-CoA hydratase
BVB96_24025	COG1309	transcriptional regulator
BVB96_24030	COG0318	PFAM AMP-dependent synthetase and ligase
BVB96_24055	COG2318	DinB family
BVB96_24085	COG1131	(ABC) transporter
BVB96_24090	COG2205	protein histidine kinase activity
BVB96_24095	COG0745	RESPONSE REGULATOR receiver
BVB96_24105	COG4895	conserved protein (DUF2196)
BVB96_24110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVB96_24125	COG4509	Sortase family
BVB96_24130	COG1120	ATPase activity
BVB96_24145	COG5386	Cell surface protein
BVB96_24155	COG5386	Cell surface protein
BVB96_24160	COG1114	Component of the transport system for branched-chain amino acids
BVB96_24165	COG1187	pseudouridine synthase activity
BVB96_24180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVB96_24180	COG1796	DNA polymerase
BVB96_24185	COG1286	toxin biosynthetic process
BVB96_24215	COG0017	Asparaginyl-tRNA synthetase
BVB96_24220	COG0072	phenylalanine-tRNA ligase activity
BVB96_24220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_24230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVB96_24240	COG1418	mRNA catabolic process
BVB96_24265	COG2814	Major facilitator Superfamily
BVB96_24270	COG1566	PFAM secretion protein HlyD family protein
BVB96_24275	COG1309	transcriptional regulator
BVB96_24280	COG1363	Peptidase, m42
BVB96_24300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVB96_24305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVB96_24315	COG1484	DNA-dependent DNA replication
BVB96_24320	COG3611	Membrane attachment protein
BVB96_24330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BVB96_24340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVB96_24345	COG0237	dephospho-CoA kinase activity
BVB96_24350	COG1971	Probably functions as a manganese efflux pump
BVB96_24355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVB96_24360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVB96_24360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVB96_24365	COG5002	protein histidine kinase activity
BVB96_24370	COG0745	RESPONSE REGULATOR receiver
BVB96_24395	COG0538	isocitrate dehydrogenase activity
BVB96_24400	COG0372	Belongs to the citrate synthase family
BVB96_24415	COG0628	permease
BVB96_24420	COG3030	protein affecting phage T7 exclusion by the F plasmid
BVB96_24445	COG1725	Transcriptional regulator
BVB96_24450	COG0281	malic enzyme
BVB96_24455	COG0587	DNA-directed DNA polymerase activity
BVB96_24470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVB96_24495	COG4109	DRTGG domain
BVB96_24510	COG0006	proline dipeptidase activity
BVB96_24550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_24555	COG0662	Cupin 2, conserved barrel domain protein
BVB96_24565	COG1476	TRANSCRIPTIONal
BVB96_24580	COG1028	Short-chain dehydrogenase reductase Sdr
BVB96_24585	COG0589	response to stress
BVB96_24635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_24655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVB96_24660	COG0827	DNA restriction-modification system
BVB96_24665	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BVB96_24670	COG3874	Sporulation protein YtfJ
BVB96_24680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVB96_24685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BVB96_24695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVB96_24710	COG1104	cysteine desulfurase activity
BVB96_24720	COG0583	DNA-binding transcription factor activity
BVB96_24725	COG0697	spore germination
BVB96_24735	COG1956	GAF domain-containing protein
BVB96_24740	COG0626	cystathionine gamma-synthase activity
BVB96_24765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVB96_24775	COG1595	DNA-templated transcription, initiation
BVB96_24785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVB96_24790	COG0454	-acetyltransferase
BVB96_24795	COG0517	IMP dehydrogenase activity
BVB96_24800	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVB96_24815	COG0745	RESPONSE REGULATOR receiver
BVB96_24825	COG0666	response to abiotic stimulus
BVB96_24860	COG1609	Transcriptional regulator
BVB96_24870	COG4851	CamS sex pheromone cAM373 precursor
BVB96_24875	COG3118	belongs to the thioredoxin family
BVB96_24885	COG2309	aminopeptidase activity
BVB96_24905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_24920	COG1674	ftsk spoiiie
BVB96_24930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_24935	COG4848	Belongs to the UPF0354 family
BVB96_24940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVB96_24945	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BVB96_24950	COG1363	Peptidase, m42
BVB96_24960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_24975	COG0510	thiamine kinase activity
BVB96_24980	COG1523	belongs to the glycosyl hydrolase 13 family
BVB96_24995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVB96_25000	COG1349	DNA-binding transcription factor activity
BVB96_25005	COG1187	pseudouridine synthase activity
BVB96_25010	COG2244	polysaccharide biosynthetic process
BVB96_25015	COG2081	HI0933 family
BVB96_25025	COG2814	Major facilitator Superfamily
BVB96_25035	COG3832	glyoxalase III activity
BVB96_25070	COG4975	Glucose uptake
BVB96_25085	COG0314	molybdopterin synthase activity
BVB96_25090	COG1763	Mo-molybdopterin cofactor biosynthetic process
BVB96_25095	COG0303	'Molybdopterin
BVB96_25105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVB96_25110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVB96_25130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVB96_25140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVB96_25185	COG2814	Major facilitator Superfamily
BVB96_25190	COG0475	glutathione-regulated potassium exporter activity
BVB96_25195	COG0490	domain, Protein
BVB96_25200	COG0582	viral genome integration into host DNA
BVB96_25210	COG1136	(ABC) transporter
BVB96_25230	COG1242	4 iron, 4 sulfur cluster binding
BVB96_25235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BVB96_25240	COG1131	(ABC) transporter
BVB96_25250	COG1794	racemase activity, acting on amino acids and derivatives
BVB96_25270	COG2267	carboxylic ester hydrolase activity
BVB96_25275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVB96_25280	COG0671	phosphoesterase, PA-phosphatase related
BVB96_25285	COG0438	transferase activity, transferring glycosyl groups
BVB96_25295	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVB96_25355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVB96_25360	COG5002	protein histidine kinase activity
BVB96_25365	COG4191	Histidine kinase
BVB96_25370	COG2267	carboxylic ester hydrolase activity
BVB96_25390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVB96_25395	COG1116	anion transmembrane transporter activity
BVB96_25400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVB96_25420	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BVB96_25430	COG0494	nUDIX hydrolase
BVB96_25465	COG0288	reversible hydration of carbon dioxide
BVB96_25470	COG1271	oxidase subunit
BVB96_25475	COG1294	oxidase, subunit
BVB96_25500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_25525	COG1842	Phage shock protein A
BVB96_25560	COG5002	protein histidine kinase activity
BVB96_25565	COG0745	RESPONSE REGULATOR receiver
BVB96_25600	COG1597	lipid kinase activity
BVB96_25635	COG0586	Pfam SNARE associated Golgi protein
BVB96_25645	COG0577	efflux transmembrane transporter activity
BVB96_25650	COG1136	(ABC) transporter
BVB96_25655	COG2207	Transcriptional regulator
BVB96_25655	COG3708	Transcriptional regulator
BVB96_25660	COG0745	RESPONSE REGULATOR receiver
BVB96_25665	COG2205	protein histidine kinase activity
BVB96_25670	COG0577	efflux transmembrane transporter activity
BVB96_25675	COG0577	efflux transmembrane transporter activity
BVB96_25680	COG1136	(ABC) transporter
BVB96_25720	COG3964	amidohydrolase
BVB96_25750	COG4948	Mandelate Racemase Muconate Lactonizing
BVB96_25760	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BVB96_25765	COG0596	Alpha beta hydrolase
BVB96_25770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BVB96_25775	COG1169	isochorismate synthase
BVB96_25780	COG1575	Belongs to the MenA family. Type 1 subfamily
BVB96_25785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVB96_25790	COG1278	Cold shock
BVB96_25810	COG0058	SHG alpha-glucan phosphorylase activity
BVB96_25815	COG0297	glycogen (starch) synthase activity
BVB96_25820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BVB96_25825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BVB96_25850	COG0039	L-malate dehydrogenase activity
BVB96_25950	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVB96_25995	COG1285	pathogenesis
BVB96_26000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVB96_26010	COG0166	Belongs to the GPI family
BVB96_26020	COG2155	Conserved Protein
BVB96_26025	COG1098	S1 RNA binding domain
BVB96_26030	COG0436	Aminotransferase
BVB96_26035	COG1522	sequence-specific DNA binding
BVB96_26040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVB96_26045	COG2267	carboxylic ester hydrolase activity
BVB96_26055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVB96_26075	COG5018	Exonuclease
BVB96_26080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVB96_26100	COG0423	glycine-tRNA ligase activity
BVB96_26105	COG2050	protein possibly involved in aromatic compounds catabolism
BVB96_26115	COG1268	BioY protein
BVB96_26125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVB96_26130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVB96_26145	COG3584	3D domain protein
BVB96_26160	COG1252	NADH dehydrogenase
BVB96_26175	COG3708	Transcriptional regulator
BVB96_26190	COG1683	Conserved Protein
BVB96_26210	COG0316	Belongs to the HesB IscA family
BVB96_26225	COG1252	NADH dehydrogenase
BVB96_26235	COG2274	protein secretion by the type I secretion system
BVB96_26240	COG0390	transport system, permease component
BVB96_26250	COG2824	Alkylphosphonate utilization operon protein PhnA
BVB96_26290	COG4837	Protein of unknown function (DUF1462)
BVB96_26295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BVB96_26305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVB96_26310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVB96_26320	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVB96_26325	COG0647	UMP catabolic process
BVB96_26335	COG2445	Protein of unknown function DUF86
BVB96_26340	COG1494	fructose-1,6-bisphosphatase
BVB96_26360	COG4470	Protein conserved in bacteria
BVB96_26370	COG0789	Transcriptional regulator
BVB96_26375	COG4377	Putative membrane peptidase family (DUF2324)
BVB96_26400	COG0739	heme binding
BVB96_26410	COG3377	Domain of unknown function (DUF1805)
BVB96_26415	COG0737	Belongs to the 5'-nucleotidase family
BVB96_26425	COG1695	Transcriptional regulator
BVB96_26435	COG0719	Fe-S assembly protein
BVB96_26440	COG0822	iron-sulfur transferase activity
BVB96_26445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVB96_26450	COG0719	Fe-S assembly protein
BVB96_26455	COG0396	ATPase activity
BVB96_26460	COG1464	Belongs to the NlpA lipoprotein family
BVB96_26465	COG1464	Belongs to the NlpA lipoprotein family
BVB96_26470	COG2011	ABC-type metal ion transport system permease component
BVB96_26475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVB96_26485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVB96_26490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BVB96_26505	COG1393	Belongs to the ArsC family
BVB96_26560	COG0039	L-malate dehydrogenase activity
BVB96_26585	COG1309	transcriptional regulator
BVB96_26590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVB96_26595	COG1960	acyl-CoA dehydrogenase activity
BVB96_26605	COG0183	Belongs to the thiolase family
BVB96_26610	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVB96_26610	COG1024	Enoyl-CoA hydratase
BVB96_26625	COG1686	Belongs to the peptidase S11 family
BVB96_26640	COG0011	TIGRFAM Protein of
BVB96_26645	COG0840	transmembrane signaling receptor activity
BVB96_26665	COG2814	Major facilitator Superfamily
BVB96_26670	COG0531	amino acid
BVB96_26680	COG0706	membrane insertase activity
BVB96_26690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVB96_26725	COG0586	Pfam SNARE associated Golgi protein
BVB96_26735	COG1376	ErfK ybiS ycfS ynhG family protein
BVB96_26740	COG0745	RESPONSE REGULATOR receiver
BVB96_26745	COG5002	protein histidine kinase activity
BVB96_26755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVB96_26770	COG2151	metal-sulfur cluster biosynthetic enzyme
BVB96_26780	COG1741	Belongs to the pirin family
BVB96_26795	COG0475	glutathione-regulated potassium exporter activity
BVB96_26800	COG0490	domain, Protein
BVB96_26810	COG1115	amino acid carrier protein
BVB96_26815	COG0783	Belongs to the Dps family
BVB96_26830	COG1611	Belongs to the LOG family
BVB96_26845	COG2311	Membrane
BVB96_26855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_26860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_26865	COG1115	amino acid carrier protein
BVB96_26870	COG1115	amino acid carrier protein
BVB96_26875	COG2910	NAD(P)H-binding
BVB96_26905	COG0656	L-ascorbic acid biosynthetic process
BVB96_26910	COG2814	Major facilitator Superfamily
BVB96_26915	COG1733	regulation of RNA biosynthetic process
BVB96_26925	COG1252	NADH dehydrogenase
BVB96_26930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVB96_26935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVB96_26945	COG0840	transmembrane signaling receptor activity
BVB96_26945	COG3290	protein histidine kinase activity
BVB96_26955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVB96_26960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVB96_26975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVB96_26980	COG3223	Belongs to the PsiE family
BVB96_27040	COG0557	exoribonuclease II activity
BVB96_27045	COG1647	Serine aminopeptidase, S33
BVB96_27050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVB96_27055	COG1346	cytolysis
BVB96_27165	COG4695	Portal protein
BVB96_27190	COG4974	Belongs to the 'phage' integrase family
BVB96_27205	COG0149	triose-phosphate isomerase activity
BVB96_27215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVB96_27230	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BVB96_27255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVB96_27270	COG2323	membrane
BVB96_27275	COG0740	serine-type endopeptidase activity
BVB96_27280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVB96_27290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BVB96_27300	COG1051	belongs to the nudix hydrolase family
BVB96_27310	COG0492	ferredoxin-NADP+ reductase activity
BVB96_27315	COG0457	Tetratricopeptide repeat
BVB96_27320	COG0110	maltose O-acetyltransferase activity
BVB96_27340	COG1950	PFAM Membrane protein of
BVB96_27350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVB96_27355	COG0556	nucleotide-excision repair
BVB96_27375	COG0789	Transcriptional regulator
BVB96_27405	COG0583	DNA-binding transcription factor activity
BVB96_27415	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVB96_27430	COG1132	(ABC) transporter
BVB96_27435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVB96_27440	COG0793	Belongs to the peptidase S41A family
BVB96_27440	COG3409	Peptidoglycan-binding domain 1 protein
BVB96_27445	COG2177	Part of the ABC transporter FtsEX involved in
BVB96_27450	COG2884	Cell division ATP-binding protein ftsE
BVB96_27465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BVB96_27475	COG0653	protein targeting
BVB96_27480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BVB96_27485	COG1278	Cold shock
BVB96_27490	COG1040	competence protein
BVB96_27495	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BVB96_27500	COG1388	LysM domain
BVB96_27500	COG0791	NLP P60 protein
BVB96_27505	COG1733	regulation of RNA biosynthetic process
BVB96_27515	COG1307	EDD domain protein, DegV family
BVB96_27520	COG1739	Uncharacterized protein family UPF0029
BVB96_27525	COG1316	TRANSCRIPTIONal
BVB96_27530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVB96_27535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BVB96_27540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVB96_27550	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BVB96_27550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BVB96_27565	COG3394	polysaccharide catabolic process
BVB96_27570	COG1486	melibiose metabolic process
BVB96_27575	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVB96_27580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVB96_27590	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVB96_27595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BVB96_27600	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVB96_27610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVB96_27615	COG1301	dicarboxylic acid transport
BVB96_27625	COG0346	lactoylglutathione lyase activity
BVB96_27630	COG1511	domain protein
BVB96_27635	COG0583	DNA-binding transcription factor activity
BVB96_27640	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BVB96_27655	COG1271	oxidase subunit
BVB96_27660	COG1294	oxidase, subunit
BVB96_27665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVB96_27675	COG1620	l-lactate permease
BVB96_27685	COG2389	metal-binding protein
BVB96_27695	COG1368	sulfuric ester hydrolase activity
BVB96_27715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BVB96_27735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVB96_27745	COG1388	LysM domain
BVB96_27745	COG3584	3D domain protein
BVB96_27770	COG4715	Zinc finger, swim domain protein
BVB96_27775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVB96_27805	COG1191	sigma factor activity
BVB96_27815	COG0577	efflux transmembrane transporter activity
BVB96_27820	COG1136	(ABC) transporter
BVB96_27855	COG5002	protein histidine kinase activity
BVB96_27860	COG0745	RESPONSE REGULATOR receiver
BVB96_27865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVB96_27880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVB96_27885	COG1134	teichoic acid transport
BVB96_27890	COG1682	transport, permease protein
BVB96_27895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVB96_27940	COG1609	Transcriptional regulator
BVB96_27955	COG0739	heme binding
BVB96_27975	COG2385	sporulation resulting in formation of a cellular spore
BVB96_27980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVB96_27990	COG4836	Membrane
BVB96_27995	COG1007	ATP synthesis coupled electron transport
BVB96_28000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVB96_28005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVB96_28015	COG0839	Belongs to the complex I subunit 6 family
BVB96_28030	COG0649	NAD binding
BVB96_28035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVB96_28045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVB96_28050	COG3300	MHYT domain
BVB96_28050	COG5001	Diguanylate cyclase
BVB96_28105	COG0356	it plays a direct role in the translocation of protons across the membrane
BVB96_28140	COG0698	ribose 5-phosphate isomerase
BVB96_28150	COG2190	(PTS) system
BVB96_28155	COG2259	Doxx family
BVB96_28160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVB96_28175	COG0009	L-threonylcarbamoyladenylate synthase
BVB96_28190	COG2890	protein-(glutamine-N5) methyltransferase activity
BVB96_28195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVB96_28210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVB96_28215	COG1494	fructose-1,6-bisphosphatase
BVB96_28225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVB96_28240	COG4821	SIS domain
BVB96_28250	COG3343	RNA polymerase activity
BVB96_28260	COG1960	acyl-CoA dehydrogenase activity
BVB96_28265	COG1960	acyl-CoA dehydrogenase activity
BVB96_28270	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVB96_28275	COG0183	Belongs to the thiolase family
BVB96_28280	COG2181	nitrate reductase activity
BVB96_28280	COG0247	lactate metabolic process
BVB96_28285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVB96_28295	COG3300	MHYT domain
BVB96_28295	COG5001	Diguanylate cyclase
BVB96_28320	COG2197	response regulator
BVB96_28325	COG4585	Histidine kinase
BVB96_28330	COG0842	Transport permease protein
BVB96_28335	COG1131	(ABC) transporter
BVB96_28340	COG0024	Methionine aminopeptidase
BVB96_28360	COG2234	aminopeptidase activity
BVB96_28380	COG1595	DNA-templated transcription, initiation
BVB96_28385	COG0018	arginyl-trna synthetase
BVB96_28390	COG4506	Protein conserved in bacteria
BVB96_28395	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVB96_28415	COG0010	Belongs to the arginase family
BVB96_28420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BVB96_28425	COG2814	Major facilitator Superfamily
BVB96_28430	COG0789	Transcriptional regulator
BVB96_28435	COG0584	glycerophosphoryl diester phosphodiesterase
BVB96_28440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVB96_28450	COG1994	Peptidase M50
BVB96_28460	COG1078	dGTPase activity
BVB96_28465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVB96_28470	COG1120	ATPase activity
BVB96_28475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_28480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_28485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVB96_28505	COG0095	Lipoate-protein ligase
BVB96_28510	COG0280	phosphate acetyltransferase
BVB96_28525	COG3773	Cell wall hydrolase
BVB96_28535	COG2363	Small membrane protein
BVB96_28545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVB96_28550	COG2233	PERMEase
BVB96_28555	COG0561	phosphatase activity
BVB96_28560	COG2814	Major facilitator Superfamily
BVB96_28570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BVB96_28575	COG1131	(ABC) transporter
BVB96_28580	COG2755	lipolytic protein G-D-S-L family
BVB96_28585	COG1609	Transcriptional regulator
BVB96_28595	COG0460	homoserine dehydrogenase
BVB96_28615	COG1011	Hydrolase
BVB96_28620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVB96_28630	COG2197	response regulator
BVB96_28640	COG0351	phosphomethylpyrimidine kinase
BVB96_28645	COG3706	GGDEF domain
BVB96_28650	COG2879	small protein
BVB96_28655	COG1966	Carbon starvation protein
BVB96_28660	COG3279	Response regulator of the LytR AlgR family
BVB96_28665	COG0477	Major facilitator Superfamily
BVB96_28690	COG0840	transmembrane signaling receptor activity
BVB96_28700	COG1607	acyl-coa hydrolase
BVB96_28715	COG0488	(ABC) transporter
BVB96_28745	COG0463	Glycosyl transferase, family 2
BVB96_28750	COG1309	transcriptional regulator
BVB96_28755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVB96_28760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVB96_28760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVB96_28765	COG0628	permease
BVB96_28780	COG3279	Response regulator of the LytR AlgR family
BVB96_28785	COG3275	phosphorelay sensor kinase activity
BVB96_28790	COG2814	Major facilitator Superfamily
BVB96_28795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVB96_28800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BVB96_28810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVB96_28830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVB96_28835	COG1272	protein, Hemolysin III
BVB96_28860	COG1164	Oligoendopeptidase f
BVB96_28880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVB96_28885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVB96_28890	COG4853	Protein conserved in bacteria
BVB96_28895	COG4863	YycH protein
BVB96_28900	COG5002	protein histidine kinase activity
BVB96_28905	COG0745	RESPONSE REGULATOR receiver
BVB96_28935	COG0305	Participates in initiation and elongation during chromosome replication
BVB96_28945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BVB96_28950	COG4241	membrane
BVB96_28960	COG0629	single-stranded DNA binding
BVB96_28970	COG0012	GTP binding
BVB96_28975	COG4481	Protein conserved in bacteria
BVB96_28980	COG0668	transmembrane transport
BVB96_28990	COG1475	DNA binding
BVB96_28995	COG1192	Involved in chromosome partitioning
BVB96_29015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVB96_29020	COG1847	R3H domain protein
BVB96_29025	COG0706	membrane insertase activity
BVB96_29090	COG3344	reverse transcriptase
BVB96_29190	COG3344	reverse transcriptase
BVB96_29405	COG4962	Type ii secretion system protein e
BVB96_29545	COG2311	Membrane
BVB96_29570	COG4196	transglutaminase domain protein
BVB96_29575	COG0671	phosphoesterase, PA-phosphatase related
BVB96_29605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVB96_29610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BVB96_29825	COG4974	Belongs to the 'phage' integrase family
BVB96_29865	COG2801	Transposase and inactivated derivatives
BVB96_29895	COG3443	Belongs to the bacterial solute-binding protein 9 family
BVB96_29910	COG4974	Belongs to the 'phage' integrase family
BVB96_29935	COG0457	Tetratricopeptide repeat
BVB96_29940	COG1923	regulation of RNA biosynthetic process
BVB96_30180	COG1192	Involved in chromosome partitioning
BVB96_30240	COG1683	Conserved Protein
BVB96_30245	COG1309	transcriptional regulator
BVB96_30330	COG0681	Belongs to the peptidase S26 family
BVB96_30360	COG1280	lysine exporter protein (LysE YggA)
BVB96_30410	COG4166	transmembrane transport
BVB96_30425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII