locus-tag	class	description
KM395_00010	COG0592	DNA-directed DNA polymerase activity
KM395_00015	COG2501	S4 domain
KM395_00025	COG0187	DNA topoisomerase II activity
KM395_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM395_00065	COG0516	GMP reductase activity
KM395_00065	COG0517	IMP dehydrogenase activity
KM395_00070	COG1686	Belongs to the peptidase S11 family
KM395_00100	COG1428	Deoxynucleoside kinase
KM395_00105	COG1428	Deoxynucleoside kinase
KM395_00110	COG1335	isochorismatase
KM395_00115	COG0590	tRNA wobble adenosine to inosine editing
KM395_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM395_00180	COG1982	Orn Lys Arg decarboxylase major
KM395_00190	COG0470	DNA polymerase III
KM395_00195	COG1774	PSP1 C-terminal conserved region
KM395_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM395_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM395_00220	COG2002	toxin-antitoxin pair type II binding
KM395_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM395_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM395_00230	COG0084	hydrolase, TatD family'
KM395_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM395_00250	COG4466	Protein conserved in bacteria
KM395_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM395_00270	COG0251	oxidation-reduction process
KM395_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM395_00305	COG2002	toxin-antitoxin pair type II binding
KM395_00310	COG2244	polysaccharide biosynthetic process
KM395_00315	COG3956	TIGRFAM MazG family protein
KM395_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM395_00340	COG1098	S1 RNA binding domain
KM395_00355	COG2208	phosphoserine phosphatase activity
KM395_00360	COG0037	tRNA processing
KM395_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM395_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM395_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM395_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM395_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM395_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM395_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM395_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM395_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM395_00420	COG1396	sequence-specific DNA binding
KM395_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM395_00455	COG3880	PFAM UvrB UvrC protein
KM395_00465	COG0542	response to heat
KM395_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM395_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM395_00500	COG1045	serine acetyltransferase
KM395_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM395_00520	COG3688	RNA-binding protein containing a PIN domain
KM395_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM395_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM395_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM395_00565	COG2813	Specifically methylates the guanine in position
KM395_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM395_00580	COG1358	cellular component organization or biogenesis
KM395_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM395_00710	COG0201	protein transport
KM395_00720	COG0024	Methionine aminopeptidase
KM395_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM395_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM395_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM395_00795	COG0489	protein tyrosine kinase activity
KM395_00805	COG2194	sulfuric ester hydrolase activity
KM395_00810	COG0726	polysaccharide deacetylase
KM395_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM395_00895	COG4856	YbbR-like protein
KM395_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM395_00915	COG0596	Alpha beta hydrolase
KM395_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM395_00940	COG4946	Tricorn protease homolog
KM395_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM395_00940	COG1506	peptidase
KM395_00975	COG2011	ABC-type metal ion transport system permease component
KM395_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM395_00985	COG1464	Belongs to the NlpA lipoprotein family
KM395_00990	COG0604	alcohol dehydrogenase
KM395_01000	COG0277	FAD linked oxidase domain protein
KM395_01005	COG2271	Major facilitator Superfamily
KM395_01015	COG2814	Major facilitator Superfamily
KM395_01030	COG0601	transmembrane transport
KM395_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM395_01040	COG0444	Belongs to the ABC transporter superfamily
KM395_01045	COG4608	Belongs to the ABC transporter superfamily
KM395_01050	COG4166	transmembrane transport
KM395_01060	COG2207	Transcriptional regulator
KM395_01075	COG4166	transmembrane transport
KM395_01080	COG4166	transmembrane transport
KM395_01085	COG0656	L-ascorbic acid biosynthetic process
KM395_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM395_01105	COG4149	molybdate abc transporter
KM395_01115	COG1910	domain protein
KM395_01125	COG0583	DNA-binding transcription factor activity
KM395_01130	COG0697	spore germination
KM395_01145	COG0204	Acyl-transferase
KM395_01155	COG1609	Transcriptional regulator
KM395_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_01175	COG0084	hydrolase, TatD family'
KM395_01180	COG5298	Protein conserved in bacteria
KM395_01205	COG0488	(ABC) transporter
KM395_01220	COG0747	negative chemotaxis
KM395_01225	COG0601	transmembrane transport
KM395_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM395_01235	COG0444	Belongs to the ABC transporter superfamily
KM395_01240	COG4608	Belongs to the ABC transporter superfamily
KM395_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM395_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM395_01290	COG2814	Major facilitator Superfamily
KM395_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM395_01310	COG4294	response to UV
KM395_01315	COG0457	Tetratricopeptide repeat
KM395_01315	COG0705	Rhomboid family
KM395_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM395_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM395_01335	COG0864	Transcriptional regulator
KM395_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM395_01345	COG2183	response to ionizing radiation
KM395_01440	COG0802	atpase or kinase
KM395_01445	COG1214	PFAM Peptidase M22, glycoprotease
KM395_01450	COG0456	acetyltransferase
KM395_01460	COG0488	(ABC) transporter
KM395_01475	COG1266	CAAX protease self-immunity
KM395_01495	COG2252	PERMEase
KM395_01505	COG5002	protein histidine kinase activity
KM395_01535	COG2226	methyltransferase
KM395_01575	COG1968	undecaprenyl-diphosphatase activity
KM395_01590	COG2205	protein histidine kinase activity
KM395_01595	COG0745	RESPONSE REGULATOR receiver
KM395_01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM395_01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM395_01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM395_01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM395_01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM395_01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM395_01670	COG0151	Belongs to the GarS family
KM395_01695	COG0210	DNA helicase
KM395_01705	COG4851	CamS sex pheromone cAM373 precursor
KM395_01725	COG1335	isochorismatase
KM395_01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM395_01735	COG2011	ABC-type metal ion transport system permease component
KM395_01740	COG1464	Belongs to the NlpA lipoprotein family
KM395_01760	COG1846	Transcriptional regulator
KM395_01785	COG1597	lipid kinase activity
KM395_01790	COG0546	phosphoglycolate phosphatase activity
KM395_01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM395_01805	COG1012	belongs to the aldehyde dehydrogenase family
KM395_01810	COG2076	Multidrug Resistance protein
KM395_01815	COG2309	aminopeptidase activity
KM395_01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM395_01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM395_01850	COG4807	Protein conserved in bacteria
KM395_01875	COG1757	Na H antiporter
KM395_01880	COG1473	amidohydrolase
KM395_01895	COG0450	alkyl hydroperoxide reductase
KM395_01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_01940	COG0166	Belongs to the GPI family
KM395_01975	COG5002	protein histidine kinase activity
KM395_01995	COG3541	Predicted nucleotidyltransferase
KM395_02000	COG2814	Major facilitator Superfamily
KM395_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM395_02005	COG0723	plastoquinol--plastocyanin reductase activity
KM395_02015	COG0765	amino acid transport
KM395_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM395_02030	COG0840	transmembrane signaling receptor activity
KM395_02035	COG0840	transmembrane signaling receptor activity
KM395_02040	COG0366	Alpha amylase catalytic
KM395_02045	COG2190	(PTS) system
KM395_02045	COG1263	PTS System
KM395_02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM395_02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM395_02100	COG1116	anion transmembrane transporter activity
KM395_02105	COG0488	(ABC) transporter
KM395_02150	COG2270	Major facilitator Superfamily
KM395_02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM395_02180	COG2310	stress, protein
KM395_02185	COG2310	stress, protein
KM395_02190	COG2310	stress, protein
KM395_02195	COG0861	Integral membrane protein TerC family
KM395_02205	COG3853	Toxic anion resistance protein (TelA)
KM395_02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM395_02230	COG1295	ribonuclease BN
KM395_02235	COG2217	Heavy metal translocating P-type atpase
KM395_02240	COG0697	spore germination
KM395_02260	COG0586	Pfam SNARE associated Golgi protein
KM395_02275	COG3871	stress protein (general stress protein 26)
KM395_02280	COG0387	Pfam Sodium calcium exchanger
KM395_02290	COG0535	radical SAM domain protein
KM395_02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM395_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM395_02325	COG0582	viral genome integration into host DNA
KM395_02335	COG1396	sequence-specific DNA binding
KM395_02350	COG1396	sequence-specific DNA binding
KM395_02385	COG1484	DNA-dependent DNA replication
KM395_02615	COG0101	tRNA pseudouridine synthase activity
KM395_02625	COG3829	transcription factor binding
KM395_02635	COG0833	amino acid
KM395_02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM395_02670	COG1263	PTS System
KM395_02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM395_02690	COG0463	Glycosyl transferase, family 2
KM395_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM395_02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM395_02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM395_02745	COG1228	amidohydrolase
KM395_02750	COG1090	epimerase
KM395_02780	COG1988	membrane-bound metal-dependent
KM395_02785	COG1194	a g-specific adenine glycosylase
KM395_02810	COG1132	(ABC) transporter
KM395_02815	COG4129	membrane
KM395_02820	COG0070	glutamate synthase
KM395_02820	COG0069	glutamate synthase activity
KM395_02820	COG0067	glutamate synthase
KM395_02830	COG4555	ABC transporter
KM395_02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM395_02855	COG0735	belongs to the Fur family
KM395_02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM395_02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM395_02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM395_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM395_03005	COG2766	serine protein kinase
KM395_03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM395_03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM395_03040	COG2268	Band 7 protein
KM395_03050	COG3290	protein histidine kinase activity
KM395_03055	COG4565	transcriptional regulatory protein
KM395_03060	COG2851	Citrate transporter
KM395_03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM395_03085	COG3842	ATPase activity
KM395_03090	COG1175	transmembrane transport
KM395_03095	COG0395	ABC-type sugar transport system, permease component
KM395_03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM395_03110	COG0745	RESPONSE REGULATOR receiver
KM395_03115	COG5002	protein histidine kinase activity
KM395_03125	COG4990	cell redox homeostasis
KM395_03135	COG3290	protein histidine kinase activity
KM395_03140	COG4565	transcriptional regulatory protein
KM395_03145	COG3493	citrate carrier protein
KM395_03150	COG0281	malic enzyme
KM395_03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_03175	COG5002	protein histidine kinase activity
KM395_03180	COG0745	RESPONSE REGULATOR receiver
KM395_03185	COG0454	-acetyltransferase
KM395_03185	COG0456	acetyltransferase
KM395_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM395_03195	COG3383	formate dehydrogenase (NAD+) activity
KM395_03200	COG2427	Protein of unknown function (DUF1641)
KM395_03215	COG0531	amino acid
KM395_03220	COG0640	Transcriptional regulator
KM395_03225	COG2217	Heavy metal translocating P-type atpase
KM395_03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM395_03245	COG3227	Zinc metalloprotease (Elastase)
KM395_03265	COG2720	vancomycin resistance protein
KM395_03270	COG1316	TRANSCRIPTIONal
KM395_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_03280	COG0346	lactoylglutathione lyase activity
KM395_03285	COG1253	flavin adenine dinucleotide binding
KM395_03290	COG1027	Aspartate ammonia-lyase
KM395_03295	COG1620	l-lactate permease
KM395_03310	COG3104	oligopeptide transport
KM395_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_03335	COG2226	methyltransferase
KM395_03340	COG0156	8-amino-7-oxononanoate synthase activity
KM395_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM395_03355	COG4548	von Willebrand factor, type A
KM395_03360	COG0714	Associated with various cellular activities
KM395_03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM395_03385	COG0531	amino acid
KM395_03390	COG2188	Transcriptional regulator
KM395_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_03395	COG1263	PTS System
KM395_03400	COG0366	Alpha amylase catalytic
KM395_03420	COG0697	spore germination
KM395_03430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM395_03435	COG1115	amino acid carrier protein
KM395_03440	COG1126	abc transporter atp-binding protein
KM395_03445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM395_03450	COG0765	amino acid transport
KM395_03455	COG0765	amino acid transport
KM395_03460	COG0833	amino acid
KM395_03485	COG2378	regulation of single-species biofilm formation
KM395_03490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM395_03495	COG5002	protein histidine kinase activity
KM395_03510	COG0659	secondary active sulfate transmembrane transporter activity
KM395_03525	COG0747	negative chemotaxis
KM395_03535	COG0601	transmembrane transport
KM395_03540	COG4608	Belongs to the ABC transporter superfamily
KM395_03550	COG2271	Major facilitator Superfamily
KM395_03555	COG1846	Transcriptional regulator
KM395_03565	COG1609	Transcriptional regulator
KM395_03570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM395_03585	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM395_03590	COG1879	ABC-type sugar transport system periplasmic component
KM395_03615	COG1063	alcohol dehydrogenase
KM395_03630	COG3568	Endonuclease Exonuclease Phosphatase
KM395_03655	COG1968	undecaprenyl-diphosphatase activity
KM395_03660	COG0840	transmembrane signaling receptor activity
KM395_03665	COG3584	3D domain protein
KM395_03665	COG1388	LysM domain
KM395_03670	COG1476	TRANSCRIPTIONal
KM395_03685	COG3104	oligopeptide transport
KM395_03690	COG1114	Component of the transport system for branched-chain amino acids
KM395_03705	COG1113	amino acid transport
KM395_03710	COG2252	PERMEase
KM395_03735	COG0569	domain protein
KM395_03735	COG0475	glutathione-regulated potassium exporter activity
KM395_03750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM395_03755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM395_03760	COG0833	amino acid
KM395_03765	COG4990	cell redox homeostasis
KM395_03780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM395_03785	COG0697	spore germination
KM395_03790	COG0531	amino acid
KM395_03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM395_03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM395_03810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM395_03810	COG1918	ferrous iron import across plasma membrane
KM395_03815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM395_03820	COG0573	inorganic phosphate transmembrane transporter activity
KM395_03825	COG0581	inorganic phosphate transmembrane transporter activity
KM395_03835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM395_03960	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM395_03980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM395_03985	COG1116	anion transmembrane transporter activity
KM395_03990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM395_03995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM395_04000	COG0352	thiamine-phosphate diphosphorylase activity
KM395_04005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM395_04010	COG2104	thiamine diphosphate biosynthetic process
KM395_04020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM395_04025	COG0351	phosphomethylpyrimidine kinase
KM395_04065	COG2205	protein histidine kinase activity
KM395_04070	COG2814	Major facilitator Superfamily
KM395_04075	COG1846	Transcriptional regulator
KM395_04090	COG2252	PERMEase
KM395_04095	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_04110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM395_04115	COG1621	beta-fructofuranosidase activity
KM395_04120	COG1263	PTS System
KM395_04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_04125	COG1609	Transcriptional regulator
KM395_04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM395_04140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM395_04175	COG0778	Nitroreductase
KM395_04180	COG2719	SpoVR family
KM395_04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM395_04210	COG1937	Protein conserved in bacteria
KM395_04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM395_04220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_04225	COG0425	Belongs to the sulfur carrier protein TusA family
KM395_04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_04240	COG2210	Belongs to the sulfur carrier protein TusA family
KM395_04245	COG0730	response to heat
KM395_04255	COG1316	TRANSCRIPTIONal
KM395_04260	COG0604	alcohol dehydrogenase
KM395_04265	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM395_04280	COG3711	transcriptional antiterminator
KM395_04280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM395_04285	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM395_04290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM395_04310	COG1388	LysM domain
KM395_04310	COG3584	3D domain protein
KM395_04315	COG0577	efflux transmembrane transporter activity
KM395_04320	COG1136	(ABC) transporter
KM395_04330	COG5522	Integral membrane protein (intg_mem_TP0381)
KM395_04345	COG1114	Component of the transport system for branched-chain amino acids
KM395_04350	COG3546	catalase activity
KM395_04385	COG0586	Pfam SNARE associated Golgi protein
KM395_04420	COG0531	amino acid
KM395_04425	COG0475	glutathione-regulated potassium exporter activity
KM395_04435	COG1737	Transcriptional regulator
KM395_04445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_04445	COG1263	PTS System
KM395_04455	COG2259	Doxx family
KM395_04470	COG0697	spore germination
KM395_04475	COG1522	sequence-specific DNA binding
KM395_04490	COG2076	Multidrug Resistance protein
KM395_04495	COG1309	transcriptional regulator
KM395_04500	COG2814	Major facilitator Superfamily
KM395_04505	COG1733	regulation of RNA biosynthetic process
KM395_04515	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM395_04520	COG4533	DNA binding
KM395_04525	COG2211	Major facilitator Superfamily
KM395_04535	COG0693	protein deglycase activity
KM395_04540	COG0693	protein deglycase activity
KM395_04540	COG0753	catalase activity
KM395_04550	COG0531	amino acid
KM395_04555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM395_04565	COG1012	belongs to the aldehyde dehydrogenase family
KM395_04570	COG1132	(ABC) transporter
KM395_04580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM395_04585	COG0765	amino acid transport
KM395_04590	COG1126	abc transporter atp-binding protein
KM395_04605	COG0189	ligase activity
KM395_04635	COG0028	Belongs to the TPP enzyme family
KM395_04640	COG3527	Alpha-acetolactate decarboxylase
KM395_04655	COG0561	phosphatase activity
KM395_04670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM395_04685	COG0659	secondary active sulfate transmembrane transporter activity
KM395_04705	COG0653	protein targeting
KM395_04710	COG2244	polysaccharide biosynthetic process
KM395_04720	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM395_04725	COG4196	transglutaminase domain protein
KM395_04740	COG1696	Membrane protein involved in D-alanine export
KM395_04755	COG1024	Enoyl-CoA hydratase
KM395_04775	COG1363	Peptidase, m42
KM395_04795	COG3938	Belongs to the proline racemase family
KM395_04835	COG0601	transmembrane transport
KM395_04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM395_04850	COG4608	Belongs to the ABC transporter superfamily
KM395_04855	COG0322	excinuclease ABC activity
KM395_04885	COG0477	Major facilitator Superfamily
KM395_04890	COG3290	protein histidine kinase activity
KM395_04895	COG4565	transcriptional regulatory protein
KM395_04900	COG3181	Tripartite tricarboxylate transporter family receptor
KM395_04930	COG4978	Transcriptional regulator
KM395_04930	COG0789	Transcriptional regulator
KM395_04945	COG0305	Participates in initiation and elongation during chromosome replication
KM395_04985	COG0477	Major facilitator Superfamily
KM395_05030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM395_05030	COG3320	Male sterility
KM395_05035	COG1309	transcriptional regulator
KM395_05055	COG1183	phosphatidylcholine synthase activity
KM395_05075	COG2376	Dihydroxyacetone kinase
KM395_05085	COG2376	Dihydroxyacetone kinase
KM395_05090	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM395_05095	COG1959	2 iron, 2 sulfur cluster binding
KM395_05175	COG3237	CsbD-like
KM395_05200	COG1191	sigma factor activity
KM395_05210	COG2208	phosphoserine phosphatase activity
KM395_05215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM395_05220	COG2205	protein histidine kinase activity
KM395_05220	COG0784	Response regulator, receiver
KM395_05220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM395_05220	COG2198	Histidine kinase
KM395_05275	COG0420	3'-5' exonuclease activity
KM395_05280	COG4717	serine-type aminopeptidase activity
KM395_05300	COG1309	transcriptional regulator
KM395_05305	COG2814	Major facilitator Superfamily
KM395_05310	COG0346	lactoylglutathione lyase activity
KM395_05315	COG0346	lactoylglutathione lyase activity
KM395_05320	COG0457	Tetratricopeptide repeat
KM395_05325	COG2267	carboxylic ester hydrolase activity
KM395_05345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM395_05350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM395_05360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM395_05400	COG0477	Major facilitator Superfamily
KM395_05405	COG0477	Major facilitator Superfamily
KM395_05415	COG3973	AAA domain
KM395_05420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM395_05440	COG4980	gas vesicle protein
KM395_05445	COG0537	adenosine 5'-monophosphoramidase activity
KM395_05450	COG1131	(ABC) transporter
KM395_05455	COG4473	ABC transporter
KM395_05470	COG1309	transcriptional regulator
KM395_05480	COG3402	PFAM membrane-flanked domain
KM395_05530	COG3402	PFAM membrane-flanked domain
KM395_05535	COG3428	Bacterial PH domain
KM395_05540	COG2329	Antibiotic biosynthesis monooxygenase
KM395_05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM395_05550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM395_05555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM395_05560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM395_05595	COG1309	transcriptional regulator
KM395_05600	COG1511	domain protein
KM395_05625	COG1609	Transcriptional regulator
KM395_05635	COG1234	tRNA 3'-trailer cleavage
KM395_05640	COG0095	Lipoate-protein ligase
KM395_05650	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_05680	COG3209	COG3209 Rhs family protein
KM395_05720	COG1078	dGTPase activity
KM395_05730	COG1595	DNA-templated transcription, initiation
KM395_05750	COG2205	protein histidine kinase activity
KM395_05755	COG0745	RESPONSE REGULATOR receiver
KM395_05780	COG0501	Belongs to the peptidase M48B family
KM395_05785	COG0840	transmembrane signaling receptor activity
KM395_05790	COG0697	spore germination
KM395_05810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM395_05815	COG2224	Isocitrate lyase
KM395_05840	COG4903	ComK protein
KM395_05845	COG0398	Pfam SNARE associated Golgi protein
KM395_05855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM395_05860	COG1074	ATP-dependent DNA helicase activity
KM395_05905	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM395_05930	COG0367	asparagine synthase
KM395_05935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM395_05940	COG0753	catalase activity
KM395_05945	COG0004	ammonium transporteR
KM395_05965	COG2996	Protein conserved in bacteria
KM395_05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM395_05985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_06000	COG0561	phosphatase activity
KM395_06010	COG0542	response to heat
KM395_06020	COG2267	carboxylic ester hydrolase activity
KM395_06035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM395_06045	COG5504	Zn-dependent protease
KM395_06055	COG0180	Tryptophanyl-tRNA synthetase
KM395_06065	COG4166	transmembrane transport
KM395_06070	COG0601	transmembrane transport
KM395_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM395_06080	COG0444	Belongs to the ABC transporter superfamily
KM395_06085	COG4608	Belongs to the ABC transporter superfamily
KM395_06090	COG0534	Mate efflux family protein
KM395_06095	COG4166	transmembrane transport
KM395_06110	COG0861	Integral membrane protein TerC family
KM395_06115	COG4862	establishment of competence for transformation
KM395_06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM395_06130	COG1164	Oligoendopeptidase f
KM395_06140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM395_06145	COG2346	COG2346, Truncated hemoglobins
KM395_06150	COG4116	CYTH
KM395_06160	COG2357	RelA SpoT domain protein
KM395_06170	COG0564	pseudouridine synthase activity
KM395_06190	COG0463	Glycosyl transferase, family 2
KM395_06190	COG1216	Glycosyl transferase, family 2
KM395_06210	COG0463	Glycosyl transferase, family 2
KM395_06210	COG0457	Tetratricopeptide repeat
KM395_06230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM395_06245	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM395_06290	COG2153	protein acetylation
KM395_06300	COG2382	esterase
KM395_06315	COG5492	domain, Protein
KM395_06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM395_06330	COG0512	Glutamine amidotransferase of anthranilate synthase
KM395_06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM395_06365	COG1620	l-lactate permease
KM395_06370	COG5634	Uncharacterized conserved protein (DUF2278)
KM395_06425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM395_06435	COG1476	TRANSCRIPTIONal
KM395_06495	COG2226	methyltransferase
KM395_06505	COG1686	Belongs to the peptidase S11 family
KM395_06510	COG0681	Belongs to the peptidase S26 family
KM395_06545	COG1012	belongs to the aldehyde dehydrogenase family
KM395_06550	COG3842	ATPase activity
KM395_06555	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM395_06560	COG1177	transmembrane transport
KM395_06565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM395_06575	COG2409	Drug exporters of the RND superfamily
KM395_06585	COG0564	pseudouridine synthase activity
KM395_06595	COG2340	Cysteine-rich secretory protein family
KM395_06600	COG0247	lactate metabolic process
KM395_06605	COG0277	FAD linked oxidase domain protein
KM395_06610	COG3835	regulator
KM395_06620	COG0745	RESPONSE REGULATOR receiver
KM395_06625	COG5002	protein histidine kinase activity
KM395_06630	COG2186	Transcriptional regulator
KM395_06650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM395_06665	COG2116	formate transmembrane transporter activity
KM395_06670	COG0861	Integral membrane protein TerC family
KM395_06685	COG2030	dehydratase
KM395_06705	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_06710	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM395_06715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM395_06720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM395_06735	COG1840	ABC-type Fe3 transport system, periplasmic component
KM395_06765	COG1349	DNA-binding transcription factor activity
KM395_06785	COG2861	carbohydrate metabolic process
KM395_06795	COG3852	Histidine kinase
KM395_06800	COG1846	Transcriptional regulator
KM395_06810	COG2318	DinB family
KM395_06815	COG5002	protein histidine kinase activity
KM395_06825	COG0720	synthase
KM395_06840	COG4873	Protein conserved in bacteria
KM395_06870	COG1780	Probably involved in ribonucleotide reductase function
KM395_06890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM395_06895	COG1725	Transcriptional regulator
KM395_06900	COG1131	(ABC) transporter
KM395_06910	COG1131	(ABC) transporter
KM395_06915	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM395_06930	COG1522	sequence-specific DNA binding
KM395_06940	COG1335	isochorismatase
KM395_06950	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM395_06955	COG2070	2-Nitropropane dioxygenase
KM395_06960	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM395_06970	COG1696	Membrane protein involved in D-alanine export
KM395_06995	COG0716	FMN binding
KM395_07010	COG3173	Aminoglycoside phosphotransferase
KM395_07030	COG0534	Mate efflux family protein
KM395_07035	COG1968	undecaprenyl-diphosphatase activity
KM395_07050	COG1846	Transcriptional regulator
KM395_07060	COG1301	dicarboxylic acid transport
KM395_07065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM395_07070	COG4709	membrane
KM395_07075	COG3874	Sporulation protein YtfJ
KM395_07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM395_07105	COG0028	Belongs to the TPP enzyme family
KM395_07110	COG0440	acetolactate synthase activity
KM395_07115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM395_07125	COG0473	3-isopropylmalate dehydrogenase activity
KM395_07150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM395_07185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM395_07200	COG1183	phosphatidylcholine synthase activity
KM395_07205	COG1368	sulfuric ester hydrolase activity
KM395_07215	COG0019	diaminopimelate decarboxylase activity
KM395_07235	COG0529	Catalyzes the synthesis of activated sulfate
KM395_07240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM395_07260	COG1648	precorrin-2 dehydrogenase activity
KM395_07265	COG0733	neurotransmitter:sodium symporter activity
KM395_07285	COG1757	Na H antiporter
KM395_07300	COG4758	membrane
KM395_07305	COG4585	Histidine kinase
KM395_07310	COG2197	response regulator
KM395_07320	COG1114	Component of the transport system for branched-chain amino acids
KM395_07330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM395_07355	COG1017	nitric oxide dioxygenase activity
KM395_07355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM395_07370	COG0730	response to heat
KM395_07375	COG0306	phosphate transporter
KM395_07380	COG1392	Phosphate transport regulator
KM395_07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM395_07400	COG3852	Histidine kinase
KM395_07405	COG1801	Protein of unknown function DUF72
KM395_07415	COG0582	viral genome integration into host DNA
KM395_07420	COG5002	protein histidine kinase activity
KM395_07440	COG0392	lysyltransferase activity
KM395_07440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM395_07455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM395_07460	COG1686	Belongs to the peptidase S11 family
KM395_07465	COG2715	membrane protein required for spore maturation
KM395_07470	COG0700	Nucleoside recognition
KM395_07475	COG1187	pseudouridine synthase activity
KM395_07485	COG1333	cytochrome c biogenesis protein
KM395_07490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM395_07495	COG0745	RESPONSE REGULATOR receiver
KM395_07500	COG5002	protein histidine kinase activity
KM395_07505	COG2096	Adenosyltransferase
KM395_07520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM395_07525	COG1141	Ferredoxin
KM395_07530	COG4955	Helix-turn-helix domain
KM395_07535	COG0514	ATP-dependent DNA helicase (RecQ)
KM395_07540	COG1266	CAAX protease self-immunity
KM395_07560	COG4862	establishment of competence for transformation
KM395_07565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM395_07585	COG0492	ferredoxin-NADP+ reductase activity
KM395_07660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM395_07675	COG0142	geranyltranstransferase activity
KM395_07685	COG0142	geranyltranstransferase activity
KM395_07705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM395_07710	COG0457	Tetratricopeptide repeat
KM395_07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM395_07740	COG4347	Protein of unknown function (DUF1405)
KM395_07755	COG2738	Putative neutral zinc metallopeptidase
KM395_07765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_07770	COG1694	Mazg nucleotide pyrophosphohydrolase
KM395_07785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM395_07790	COG0438	transferase activity, transferring glycosyl groups
KM395_07825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM395_07825	COG1199	ATP-dependent helicase activity
KM395_07845	COG3935	DnaD domain protein
KM395_07850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM395_07860	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM395_07860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM395_07920	COG0116	Belongs to the methyltransferase superfamily
KM395_07930	COG1199	ATP-dependent helicase activity
KM395_07935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM395_07945	COG3173	Aminoglycoside phosphotransferase
KM395_07950	COG0024	Methionine aminopeptidase
KM395_07960	COG2233	PERMEase
KM395_07965	COG2311	Membrane
KM395_07970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM395_07980	COG0456	acetyltransferase
KM395_08030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM395_08055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM395_08070	COG1215	transferase activity, transferring glycosyl groups
KM395_08075	COG0438	transferase activity, transferring glycosyl groups
KM395_08090	COG0454	-acetyltransferase
KM395_08110	COG0328	RNA-DNA hybrid ribonuclease activity
KM395_08150	COG1280	lysine exporter protein (LysE YggA)
KM395_08165	COG3162	membrane
KM395_08170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM395_08175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM395_08185	COG0475	glutathione-regulated potassium exporter activity
KM395_08190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM395_08195	COG0789	Transcriptional regulator
KM395_08195	COG4978	Transcriptional regulator
KM395_08205	COG2323	membrane
KM395_08210	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM395_08265	COG1923	regulation of RNA biosynthetic process
KM395_08280	COG1360	Flagellar Motor Protein
KM395_08285	COG2201	protein-glutamate methylesterase activity
KM395_08290	COG0643	Histidine kinase
KM395_08290	COG2198	Histidine kinase
KM395_08295	COG2198	Histidine kinase
KM395_08295	COG0643	Histidine kinase
KM395_08300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM395_08300	COG1776	CheC inhibitor of MCP methylation
KM395_08315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM395_08360	COG1815	bacterial-type flagellum-dependent cell motility
KM395_08365	COG1558	bacterial-type flagellum-dependent cell motility
KM395_08380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM395_08390	COG1157	protein secretion by the type III secretion system
KM395_08430	COG0784	Response regulator, receiver
KM395_08430	COG0835	chemotaxis
KM395_08440	COG0463	Glycosyl transferase, family 2
KM395_08475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM395_08480	COG0741	lytic transglycosylase activity
KM395_08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM395_08495	COG1776	CheC inhibitor of MCP methylation
KM395_08505	COG1338	Plays a role in the flagellum-specific transport system
KM395_08510	COG1987	bacterial-type flagellum assembly
KM395_08520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM395_08525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM395_08530	COG1419	protein localization to endoplasmic reticulum
KM395_08535	COG4786	Flagellar basal body rod
KM395_08540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM395_08565	COG1309	transcriptional regulator
KM395_08585	COG2329	Antibiotic biosynthesis monooxygenase
KM395_08610	COG0583	DNA-binding transcription factor activity
KM395_08615	COG3842	ATPase activity
KM395_08620	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM395_08630	COG1234	tRNA 3'-trailer cleavage
KM395_08655	COG1686	Belongs to the peptidase S11 family
KM395_08665	COG0406	alpha-ribazole phosphatase activity
KM395_08695	COG0367	asparagine synthase
KM395_08725	COG1802	Transcriptional regulator
KM395_08730	COG0697	spore germination
KM395_08735	COG0523	cobalamin synthesis protein
KM395_08740	COG0701	Predicted permease
KM395_08750	COG1216	Glycosyl transferase, family 2
KM395_08750	COG0438	transferase activity, transferring glycosyl groups
KM395_08755	COG1757	Na H antiporter
KM395_08760	COG0114	fumarate hydratase activity
KM395_08785	COG3340	Belongs to the peptidase S51 family
KM395_08805	COG0785	Cytochrome C biogenesis protein
KM395_08835	COG2733	membrane
KM395_08870	COG1131	(ABC) transporter
KM395_08885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM395_08890	COG0528	UMP kinase activity
KM395_08900	COG1027	Aspartate ammonia-lyase
KM395_08905	COG0281	malic enzyme
KM395_08910	COG4191	Histidine kinase
KM395_08915	COG0784	Response regulator, receiver
KM395_08920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM395_08975	COG1051	belongs to the nudix hydrolase family
KM395_08980	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM395_08990	COG2814	Major facilitator Superfamily
KM395_09005	COG1966	Carbon starvation protein
KM395_09020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_09030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM395_09040	COG2223	nitrite transmembrane transporter activity
KM395_09045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM395_09060	COG2244	polysaccharide biosynthetic process
KM395_09065	COG0733	neurotransmitter:sodium symporter activity
KM395_09075	COG5566	PFAM Mor transcription activator
KM395_09080	COG2323	membrane
KM395_09095	COG2084	Dehydrogenase
KM395_09110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM395_09120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM395_09125	COG0028	Belongs to the TPP enzyme family
KM395_09130	COG0440	acetolactate synthase activity
KM395_09135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM395_09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM395_09170	COG2814	Major facilitator Superfamily
KM395_09175	COG3384	dioxygenase
KM395_09185	COG3279	Response regulator of the LytR AlgR family
KM395_09190	COG0427	acetyl-CoA hydrolase
KM395_09210	COG1073	alpha beta
KM395_09240	COG0535	radical SAM domain protein
KM395_09245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_09265	COG1914	H( )-stimulated, divalent metal cation uptake system
KM395_09280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM395_09310	COG2390	Transcriptional regulator
KM395_09320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_09325	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM395_09340	COG4224	UPF0291 protein
KM395_09360	COG0006	proline dipeptidase activity
KM395_09380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM395_09395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM395_09410	COG1276	copper resistance
KM395_09410	COG2372	response to copper ion
KM395_09415	COG4549	nuclear export factor GLE1
KM395_09425	COG0697	spore germination
KM395_09430	COG0583	DNA-binding transcription factor activity
KM395_09435	COG1959	2 iron, 2 sulfur cluster binding
KM395_09440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM395_09445	COG0778	Nitroreductase
KM395_09455	COG0628	permease
KM395_09465	COG1231	oxidoreductase activity
KM395_09470	COG0523	cobalamin synthesis protein
KM395_09485	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_09490	COG2030	dehydratase
KM395_09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_09505	COG0411	ABC transporter
KM395_09525	COG0583	DNA-binding transcription factor activity
KM395_09535	COG1942	4-Oxalocrotonate Tautomerase
KM395_09545	COG1846	Transcriptional regulator
KM395_09555	COG1271	oxidase subunit
KM395_09560	COG1294	oxidase, subunit
KM395_09565	COG4988	ABC transporter
KM395_09570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM395_09590	COG1686	Belongs to the peptidase S11 family
KM395_09605	COG0791	NLP P60 protein
KM395_09605	COG1388	LysM domain
KM395_09620	COG0745	RESPONSE REGULATOR receiver
KM395_09625	COG5002	protein histidine kinase activity
KM395_09635	COG0300	oxidoreductase activity
KM395_09670	COG0460	homoserine dehydrogenase
KM395_09695	COG1316	TRANSCRIPTIONal
KM395_09705	COG0745	RESPONSE REGULATOR receiver
KM395_09710	COG5002	protein histidine kinase activity
KM395_09725	COG1285	pathogenesis
KM395_09730	COG1247	-acetyltransferase
KM395_09750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM395_09760	COG1082	Xylose isomerase domain protein TIM barrel
KM395_09775	COG1279	arginine transmembrane transporter activity
KM395_09785	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM395_09825	COG2002	toxin-antitoxin pair type II binding
KM395_09830	COG1404	Belongs to the peptidase S8 family
KM395_09835	COG0640	Transcriptional regulator
KM395_09840	COG0667	Aldo Keto reductase
KM395_09845	COG2814	Major facilitator Superfamily
KM395_09885	COG3949	Membrane
KM395_09890	COG0783	Belongs to the Dps family
KM395_09905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM395_09915	COG1231	oxidoreductase activity
KM395_09925	COG4989	oxidoreductase activity
KM395_09930	COG0523	cobalamin synthesis protein
KM395_09935	COG0456	acetyltransferase
KM395_09990	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM395_09990	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM395_10000	COG0702	epimerase
KM395_10010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM395_10020	COG4166	transmembrane transport
KM395_10035	COG0406	alpha-ribazole phosphatase activity
KM395_10045	COG5337	Spore coat protein CotH
KM395_10050	COG1051	belongs to the nudix hydrolase family
KM395_10055	COG0586	Pfam SNARE associated Golgi protein
KM395_10060	COG2244	polysaccharide biosynthetic process
KM395_10070	COG0701	Predicted permease
KM395_10075	COG3689	TIGRFAM TIGR03943 family protein
KM395_10080	COG1607	acyl-coa hydrolase
KM395_10090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM395_10105	COG0702	epimerase
KM395_10110	COG2839	Protein conserved in bacteria
KM395_10115	COG1253	flavin adenine dinucleotide binding
KM395_10130	COG1114	Component of the transport system for branched-chain amino acids
KM395_10135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM395_10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM395_10165	COG1876	peptidase activity
KM395_10175	COG0154	amidase activity
KM395_10180	COG2211	Major facilitator Superfamily
KM395_10200	COG0561	phosphatase activity
KM395_10210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM395_10215	COG4106	trans-aconitate 2-methyltransferase activity
KM395_10230	COG1819	glycosyl
KM395_10235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_10240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_10265	COG0456	acetyltransferase
KM395_10315	COG3874	Sporulation protein YtfJ
KM395_10340	COG2226	methyltransferase
KM395_10365	COG0346	lactoylglutathione lyase activity
KM395_10375	COG0604	alcohol dehydrogenase
KM395_10380	COG1595	DNA-templated transcription, initiation
KM395_10405	COG0386	Belongs to the glutathione peroxidase family
KM395_10410	COG1305	Transglutaminase-like
KM395_10415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM395_10420	COG0714	Associated with various cellular activities
KM395_10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM395_10440	COG1140	nitrate reductase beta subunit
KM395_10445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM395_10450	COG2181	nitrate reductase activity
KM395_10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM395_10475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM395_10480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM395_10485	COG0303	'Molybdopterin
KM395_10490	COG0314	molybdopterin synthase activity
KM395_10500	COG2223	nitrite transmembrane transporter activity
KM395_10515	COG1648	precorrin-2 dehydrogenase activity
KM395_10525	COG1587	Uroporphyrinogen-III synthase
KM395_10525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM395_10530	COG2146	nitrite reductase [NAD(P)H] activity
KM395_10535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM395_10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM395_10575	COG2359	stage V sporulation protein S
KM395_10590	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM395_10605	COG1418	mRNA catabolic process
KM395_10610	COG0488	(ABC) transporter
KM395_10625	COG0629	single-stranded DNA binding
KM395_10640	COG1413	lyase activity
KM395_10655	COG2521	methyltransferase
KM395_10655	COG2136	Putative SAM-dependent methyltransferase
KM395_10660	COG0018	arginyl-trna synthetase
KM395_10685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM395_10705	COG0017	Asparaginyl-tRNA synthetase
KM395_10725	COG1674	ftsk spoiiie
KM395_10795	COG1929	Belongs to the glycerate kinase type-1 family
KM395_10800	COG0471	metal ion transport
KM395_10805	COG0745	RESPONSE REGULATOR receiver
KM395_10810	COG5002	protein histidine kinase activity
KM395_10810	COG3850	Histidine kinase
KM395_10825	COG0733	neurotransmitter:sodium symporter activity
KM395_10850	COG2610	gluconate transmembrane transporter activity
KM395_10855	COG1454	alcohol dehydrogenase
KM395_10860	COG1794	racemase activity, acting on amino acids and derivatives
KM395_10870	COG0456	acetyltransferase
KM395_10885	COG1131	(ABC) transporter
KM395_10900	COG0546	phosphoglycolate phosphatase activity
KM395_10920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM395_10935	COG0768	penicillin binding
KM395_10940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM395_10945	COG0204	Acyl-transferase
KM395_10950	COG1272	protein, Hemolysin III
KM395_10960	COG0805	protein transport
KM395_10970	COG1307	EDD domain protein, DegV family
KM395_10975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM395_10980	COG1999	signal sequence binding
KM395_10985	COG0071	Belongs to the small heat shock protein (HSP20) family
KM395_10990	COG0367	asparagine synthase
KM395_11005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_11010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM395_11035	COG1051	belongs to the nudix hydrolase family
KM395_11045	COG0668	transmembrane transport
KM395_11050	COG2203	Gaf domain
KM395_11050	COG4585	Histidine kinase
KM395_11055	COG2197	response regulator
KM395_11065	COG1064	alcohol dehydrogenase
KM395_11090	COG1070	Carbohydrate kinase
KM395_11095	COG1070	Carbohydrate kinase
KM395_11125	COG1125	glycine betaine transport
KM395_11125	COG0517	IMP dehydrogenase activity
KM395_11130	COG1174	glycine betaine transport
KM395_11165	COG1253	flavin adenine dinucleotide binding
KM395_11170	COG1012	belongs to the aldehyde dehydrogenase family
KM395_11175	COG5506	Protein of unknown function (DUF1694)
KM395_11190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM395_11195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM395_11200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM395_11205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM395_11210	COG0456	acetyltransferase
KM395_11215	COG3829	transcription factor binding
KM395_11220	COG1509	lysine 2,3-aminomutase activity
KM395_11260	COG4326	sporulation control protein
KM395_11265	COG0671	phosphoesterase, PA-phosphatase related
KM395_11270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM395_11275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM395_11305	COG1715	Restriction endonuclease
KM395_11305	COG1787	Restriction endonuclease
KM395_11395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM395_11440	COG2814	Major facilitator Superfamily
KM395_11445	COG4841	protein insertion into membrane
KM395_11450	COG0372	Belongs to the citrate synthase family
KM395_11455	COG2079	MmgE PrpD family protein
KM395_11460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM395_11465	COG1960	acyl-CoA dehydrogenase activity
KM395_11470	COG2084	Dehydrogenase
KM395_11480	COG1280	lysine exporter protein (LysE YggA)
KM395_11485	COG1024	Enoyl-CoA hydratase
KM395_11500	COG0420	3'-5' exonuclease activity
KM395_11505	COG0419	ATPase involved in DNA repair
KM395_11525	COG2223	nitrite transmembrane transporter activity
KM395_11530	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_11535	COG1169	isochorismate synthase
KM395_11540	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM395_11545	COG3433	isochorismatase activity
KM395_11545	COG1535	isochorismatase
KM395_11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM395_11555	COG3251	PFAM MbtH domain protein
KM395_11560	COG2814	Major facilitator Superfamily
KM395_11575	COG0776	regulation of translation
KM395_11585	COG2318	DinB family
KM395_11595	COG1115	amino acid carrier protein
KM395_11610	COG2329	Antibiotic biosynthesis monooxygenase
KM395_11615	COG1187	pseudouridine synthase activity
KM395_11620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM395_11635	COG0596	Alpha beta hydrolase
KM395_11640	COG2814	Major facilitator Superfamily
KM395_11660	COG2226	methyltransferase
KM395_11705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_11740	COG1247	-acetyltransferase
KM395_11770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM395_11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_11790	COG1278	Cold shock
KM395_11805	COG0010	Belongs to the arginase family
KM395_11810	COG0561	phosphatase activity
KM395_11850	COG0583	DNA-binding transcription factor activity
KM395_11855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM395_11870	COG0583	DNA-binding transcription factor activity
KM395_11875	COG2258	MOSC domain
KM395_11890	COG1132	(ABC) transporter
KM395_11895	COG1132	(ABC) transporter
KM395_11915	COG1396	sequence-specific DNA binding
KM395_11940	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM395_11945	COG1595	DNA-templated transcription, initiation
KM395_11970	COG1649	PFAM Uncharacterised BCR, COG1649
KM395_11995	COG2971	BadF BadG BcrA BcrD
KM395_12000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM395_12005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM395_12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_12055	COG1309	transcriptional regulator
KM395_12070	COG1136	(ABC) transporter
KM395_12070	COG0577	efflux transmembrane transporter activity
KM395_12075	COG0500	methyltransferase
KM395_12075	COG3615	Tellurite resistance protein tehB
KM395_12085	COG2226	methyltransferase
KM395_12090	COG3961	Belongs to the TPP enzyme family
KM395_12095	COG1846	Transcriptional regulator
KM395_12135	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM395_12150	COG1595	DNA-templated transcription, initiation
KM395_12160	COG0768	penicillin binding
KM395_12170	COG2367	Beta-lactamase
KM395_12175	COG0671	phosphoesterase, PA-phosphatase related
KM395_12180	COG1609	Transcriptional regulator
KM395_12185	COG2814	Major facilitator Superfamily
KM395_12190	COG0673	inositol 2-dehydrogenase activity
KM395_12200	COG1012	belongs to the aldehyde dehydrogenase family
KM395_12215	COG0191	fructose-bisphosphate aldolase activity
KM395_12220	COG3718	enzyme involved in inositol metabolism
KM395_12245	COG0457	Tetratricopeptide repeat
KM395_12250	COG1476	TRANSCRIPTIONal
KM395_12265	COG1876	peptidase activity
KM395_12285	COG1309	transcriptional regulator
KM395_12290	COG0488	(ABC) transporter
KM395_12305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_12320	COG1252	NADH dehydrogenase
KM395_12325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_12340	COG1131	(ABC) transporter
KM395_12350	COG1309	transcriptional regulator
KM395_12365	COG1960	acyl-CoA dehydrogenase activity
KM395_12370	COG0439	Biotin carboxylase
KM395_12375	COG0511	ligase activity, forming carbon-carbon bonds
KM395_12380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM395_12385	COG1024	Enoyl-CoA hydratase
KM395_12390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM395_12395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM395_12405	COG1247	-acetyltransferase
KM395_12410	COG0572	uridine kinase
KM395_12420	COG2318	DinB family
KM395_12425	COG1686	Belongs to the peptidase S11 family
KM395_12450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM395_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM395_12490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM395_12515	COG2814	Major facilitator Superfamily
KM395_12535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM395_12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_12570	COG1063	alcohol dehydrogenase
KM395_12600	COG3773	Cell wall hydrolase
KM395_12610	COG0745	RESPONSE REGULATOR receiver
KM395_12625	COG0488	(ABC) transporter
KM395_12640	COG1136	(ABC) transporter
KM395_12665	COG0460	homoserine dehydrogenase
KM395_12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_12680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM395_12745	COG2124	cytochrome p450
KM395_12780	COG0561	phosphatase activity
KM395_12790	COG5002	protein histidine kinase activity
KM395_12795	COG0768	penicillin binding
KM395_12800	COG1819	glycosyl
KM395_12805	COG1794	racemase activity, acting on amino acids and derivatives
KM395_12815	COG1122	ATPase activity
KM395_12830	COG2205	protein histidine kinase activity
KM395_12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM395_12845	COG0604	alcohol dehydrogenase
KM395_12850	COG0768	penicillin binding
KM395_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM395_12895	COG0693	protein deglycase activity
KM395_12925	COG2814	Major facilitator Superfamily
KM395_12960	COG0697	spore germination
KM395_12985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM395_12995	COG2223	nitrite transmembrane transporter activity
KM395_13010	COG2816	NAD+ diphosphatase activity
KM395_13015	COG0592	DNA-directed DNA polymerase activity
KM395_13020	COG1051	belongs to the nudix hydrolase family
KM395_13055	COG3878	Protein conserved in bacteria
KM395_13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM395_13115	COG0322	excinuclease ABC activity
KM395_13155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM395_13180	COG1011	Hydrolase
KM395_13200	COG0076	glutamate decarboxylase activity
KM395_13215	COG1523	belongs to the glycosyl hydrolase 13 family
KM395_13220	COG3227	Zinc metalloprotease (Elastase)
KM395_13240	COG0201	protein transport
KM395_13250	COG0697	spore germination
KM395_13255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_13285	COG4129	membrane
KM395_13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_13305	COG2959	enzyme of heme biosynthesis
KM395_13325	COG3483	tryptophan 2,3-dioxygenase activity
KM395_13330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM395_13335	COG3844	kynureninase activity
KM395_13340	COG1309	transcriptional regulator
KM395_13370	COG3284	Transcriptional regulator
KM395_13390	COG1349	DNA-binding transcription factor activity
KM395_13410	COG1959	2 iron, 2 sulfur cluster binding
KM395_13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM395_13430	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM395_13435	COG0022	dehydrogenase e1 component
KM395_13440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM395_13450	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_13455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM395_13455	COG0456	acetyltransferase
KM395_13485	COG4176	ABC-type proline glycine betaine transport system permease component
KM395_13490	COG4175	Glycine betaine
KM395_13490	COG0517	IMP dehydrogenase activity
KM395_13515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM395_13520	COG2153	protein acetylation
KM395_13525	COG3397	chitin binding
KM395_13540	COG2205	protein histidine kinase activity
KM395_13565	COG0658	competence protein
KM395_13565	COG2333	competence protein COMEC
KM395_13615	COG3973	AAA domain
KM395_13630	COG2105	PFAM AIG2 family protein
KM395_13635	COG0514	ATP-dependent DNA helicase (RecQ)
KM395_13655	COG4637	Psort location Cytoplasmic, score
KM395_13680	COG3397	chitin binding
KM395_13695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM395_13700	COG1115	amino acid carrier protein
KM395_13705	COG1012	belongs to the aldehyde dehydrogenase family
KM395_13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM395_13720	COG3938	Belongs to the proline racemase family
KM395_13725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM395_13765	COG0586	Pfam SNARE associated Golgi protein
KM395_13780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM395_13785	COG0519	Catalyzes the synthesis of GMP from XMP
KM395_13790	COG4166	transmembrane transport
KM395_13800	COG4948	Mandelate Racemase Muconate Lactonizing
KM395_13845	COG2936	dipeptidyl-peptidase activity
KM395_13850	COG5002	protein histidine kinase activity
KM395_13890	COG1164	Oligoendopeptidase f
KM395_13905	COG1307	EDD domain protein, DegV family
KM395_13925	COG2814	Major facilitator Superfamily
KM395_13935	COG1664	Polymer-forming cytoskeletal
KM395_13940	COG0789	Transcriptional regulator
KM395_13945	COG4533	DNA binding
KM395_13950	COG0477	Major facilitator Superfamily
KM395_13950	COG2814	Major facilitator Superfamily
KM395_13970	COG2261	transglycosylase associated protein
KM395_13985	COG2226	methyltransferase
KM395_14020	COG0436	Aminotransferase
KM395_14025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM395_14030	COG5146	pantothenate kinase activity
KM395_14050	COG1131	(ABC) transporter
KM395_14095	COG0628	permease
KM395_14105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM395_14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM395_14115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM395_14120	COG1116	anion transmembrane transporter activity
KM395_14140	COG2816	NAD+ diphosphatase activity
KM395_14160	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM395_14185	COG0697	spore germination
KM395_14190	COG2318	DinB family
KM395_14210	COG4912	Dna alkylation repair
KM395_14230	COG0861	Integral membrane protein TerC family
KM395_14235	COG1368	sulfuric ester hydrolase activity
KM395_14240	COG0488	(ABC) transporter
KM395_14250	COG1033	growth of symbiont in host cell
KM395_14250	COG2409	Drug exporters of the RND superfamily
KM395_14255	COG1033	growth of symbiont in host cell
KM395_14255	COG2409	Drug exporters of the RND superfamily
KM395_14260	COG2409	Drug exporters of the RND superfamily
KM395_14260	COG1033	growth of symbiont in host cell
KM395_14265	COG1309	transcriptional regulator
KM395_14280	COG0287	Prephenate dehydrogenase
KM395_14285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM395_14290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM395_14295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM395_14295	COG1605	Chorismate mutase
KM395_14330	COG1388	LysM domain
KM395_14330	COG3584	3D domain protein
KM395_14340	COG1595	DNA-templated transcription, initiation
KM395_14365	COG1879	ABC-type sugar transport system periplasmic component
KM395_14375	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM395_14385	COG2390	Transcriptional regulator
KM395_14420	COG2329	Antibiotic biosynthesis monooxygenase
KM395_14440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_14450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM395_14455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM395_14460	COG4187	Peptidase family M20/M25/M40
KM395_14465	COG1414	Transcriptional regulator
KM395_14470	COG0833	amino acid
KM395_14475	COG1690	Belongs to the RtcB family
KM395_14480	COG3239	Fatty acid desaturase
KM395_14485	COG1785	Belongs to the alkaline phosphatase family
KM395_14495	COG3655	Transcriptional regulator
KM395_14510	COG4377	Putative membrane peptidase family (DUF2324)
KM395_14520	COG3279	Response regulator of the LytR AlgR family
KM395_14530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_14535	COG0346	lactoylglutathione lyase activity
KM395_14555	COG0714	Associated with various cellular activities
KM395_14580	COG0463	Glycosyl transferase, family 2
KM395_14605	COG0463	Glycosyl transferase, family 2
KM395_14615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM395_14620	COG0753	catalase activity
KM395_14630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM395_14655	COG0714	Associated with various cellular activities
KM395_14665	COG0778	Nitroreductase
KM395_14670	COG1846	Transcriptional regulator
KM395_14705	COG1725	Transcriptional regulator
KM395_14715	COG1136	(ABC) transporter
KM395_14715	COG0577	efflux transmembrane transporter activity
KM395_14740	COG2207	Transcriptional regulator
KM395_14745	COG0456	acetyltransferase
KM395_14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_14785	COG0642	Histidine kinase
KM395_14790	COG0745	RESPONSE REGULATOR receiver
KM395_14795	COG0596	Alpha beta hydrolase
KM395_14825	COG0730	response to heat
KM395_14835	COG0833	amino acid
KM395_14845	COG4335	DNA alkylation repair
KM395_14885	COG0768	penicillin binding
KM395_14895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM395_14925	COG1984	allophanate hydrolase subunit 2
KM395_14930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM395_14935	COG1414	Transcriptional regulator
KM395_14950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM395_14955	COG0640	Transcriptional regulator
KM395_14965	COG1960	acyl-CoA dehydrogenase activity
KM395_14980	COG3314	Sporulation integral membrane protein YlbJ
KM395_14995	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM395_15010	COG0574	Belongs to the PEP-utilizing enzyme family
KM395_15010	COG3848	Pyruvate phosphate dikinase
KM395_15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_15030	COG5577	PFAM Coat F domain
KM395_15035	COG3403	YqcI/YcgG family
KM395_15040	COG1280	lysine exporter protein (LysE YggA)
KM395_15075	COG1063	alcohol dehydrogenase
KM395_15090	COG1027	Aspartate ammonia-lyase
KM395_15095	COG0252	asparaginase activity
KM395_15100	COG1396	sequence-specific DNA binding
KM395_15110	COG0322	excinuclease ABC activity
KM395_15115	COG0531	amino acid
KM395_15120	COG1114	Component of the transport system for branched-chain amino acids
KM395_15125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM395_15135	COG0281	malic enzyme
KM395_15150	COG0531	amino acid
KM395_15160	COG0784	Response regulator, receiver
KM395_15170	COG2066	Belongs to the glutaminase family
KM395_15175	COG1115	amino acid carrier protein
KM395_15205	COG0737	Belongs to the 5'-nucleotidase family
KM395_15210	COG0753	catalase activity
KM395_15215	COG2267	carboxylic ester hydrolase activity
KM395_15220	COG1335	isochorismatase
KM395_15240	COG0583	DNA-binding transcription factor activity
KM395_15245	COG1846	Transcriptional regulator
KM395_15285	COG0415	Belongs to the DNA photolyase family
KM395_15290	COG0288	reversible hydration of carbon dioxide
KM395_15300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM395_15305	COG5609	conserved protein (DUF2294)
KM395_15320	COG1575	Belongs to the MenA family. Type 1 subfamily
KM395_15325	COG2267	carboxylic ester hydrolase activity
KM395_15330	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM395_15335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM395_15340	COG1121	(ABC) transporter
KM395_15370	COG0798	PFAM Bile acid sodium symporter
KM395_15375	COG0346	lactoylglutathione lyase activity
KM395_15380	COG0640	Transcriptional regulator
KM395_15395	COG0443	Heat shock 70 kDa protein
KM395_15410	COG1522	sequence-specific DNA binding
KM395_15425	COG0346	lactoylglutathione lyase activity
KM395_15450	COG2169	Transcriptional regulator
KM395_15495	COG2814	Major facilitator Superfamily
KM395_15520	COG0745	RESPONSE REGULATOR receiver
KM395_15525	COG3850	Histidine kinase
KM395_15525	COG5002	protein histidine kinase activity
KM395_15550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM395_15570	COG1476	TRANSCRIPTIONal
KM395_15585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_15590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM395_15600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_15605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM395_15620	COG1136	(ABC) transporter
KM395_15625	COG0577	efflux transmembrane transporter activity
KM395_15640	COG5002	protein histidine kinase activity
KM395_15640	COG3850	Histidine kinase
KM395_15650	COG2364	Membrane
KM395_15655	COG1846	Transcriptional regulator
KM395_15665	COG2808	Putative FMN-binding domain
KM395_15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_15675	COG2271	Major facilitator Superfamily
KM395_15680	COG1556	Lactate utilization protein
KM395_15685	COG1139	Iron-sulfur cluster binding protein
KM395_15695	COG0583	DNA-binding transcription factor activity
KM395_15705	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM395_15725	COG0738	Major facilitator superfamily
KM395_15730	COG0673	inositol 2-dehydrogenase activity
KM395_15735	COG0561	phosphatase activity
KM395_15745	COG1609	Transcriptional regulator
KM395_15750	COG0457	Tetratricopeptide repeat
KM395_15770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM395_15800	COG0534	Mate efflux family protein
KM395_15820	COG2814	Major facilitator Superfamily
KM395_15825	COG1309	transcriptional regulator
KM395_15840	COG0814	amino acid
KM395_15845	COG1760	l-serine dehydratase
KM395_15850	COG1760	l-serine dehydratase
KM395_15860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM395_15865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM395_15875	COG1335	isochorismatase
KM395_15880	COG1522	sequence-specific DNA binding
KM395_15885	COG0531	amino acid
KM395_15900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM395_15920	COG1595	DNA-templated transcription, initiation
KM395_15935	COG0662	Cupin 2, conserved barrel domain protein
KM395_15940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_15940	COG2207	Transcriptional regulator
KM395_15990	COG0477	Major facilitator Superfamily
KM395_16000	COG1846	Transcriptional regulator
KM395_16005	COG2814	Major facilitator Superfamily
KM395_16015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM395_16020	COG1131	(ABC) transporter
KM395_16040	COG2076	Multidrug Resistance protein
KM395_16045	COG1309	transcriptional regulator
KM395_16055	COG2031	fatty acid transporter
KM395_16065	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM395_16095	COG1122	ATPase activity
KM395_16100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM395_16115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM395_16120	COG1288	antiporter activity
KM395_16125	COG2356	endonuclease I
KM395_16140	COG3620	sequence-specific DNA binding
KM395_16145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM395_16150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM395_16155	COG0124	histidyl-tRNA synthetase
KM395_16170	COG1733	regulation of RNA biosynthetic process
KM395_16175	COG0778	Nitroreductase
KM395_16195	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_16205	COG1131	(ABC) transporter
KM395_16230	COG1011	Hydrolase
KM395_16240	COG2365	Tyrosine phosphatase family
KM395_16265	COG0346	lactoylglutathione lyase activity
KM395_16270	COG1940	carbohydrate kinase activity
KM395_16275	COG0738	Major facilitator superfamily
KM395_16280	COG0110	maltose O-acetyltransferase activity
KM395_16290	COG0577	efflux transmembrane transporter activity
KM395_16290	COG1136	(ABC) transporter
KM395_16305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM395_16310	COG0628	permease
KM395_16330	COG2226	methyltransferase
KM395_16340	COG0477	Major facilitator Superfamily
KM395_16370	COG1253	flavin adenine dinucleotide binding
KM395_16375	COG0789	Transcriptional regulator
KM395_16380	COG0697	spore germination
KM395_16385	COG1357	PFAM Pentapeptide repeats (8 copies)
KM395_16390	COG3813	Protein conserved in bacteria
KM395_16395	COG2706	6-phosphogluconolactonase activity
KM395_16400	COG1070	Carbohydrate kinase
KM395_16410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM395_16415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM395_16425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM395_16430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM395_16435	COG0604	alcohol dehydrogenase
KM395_16440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM395_16450	COG0604	alcohol dehydrogenase
KM395_16450	COG3321	synthase
KM395_16455	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_16480	COG0656	L-ascorbic acid biosynthetic process
KM395_16485	COG2814	Major facilitator Superfamily
KM395_16500	COG0346	lactoylglutathione lyase activity
KM395_16505	COG0814	amino acid
KM395_16530	COG1393	Belongs to the ArsC family
KM395_16535	COG1733	regulation of RNA biosynthetic process
KM395_16540	COG2188	Transcriptional regulator
KM395_16550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM395_16555	COG1733	regulation of RNA biosynthetic process
KM395_16560	COG1733	regulation of RNA biosynthetic process
KM395_16575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_16595	COG0384	phenazine biosynthesis protein PhzF
KM395_16605	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_16615	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_16625	COG1733	regulation of RNA biosynthetic process
KM395_16660	COG1191	sigma factor activity
KM395_16675	COG1309	transcriptional regulator
KM395_16695	COG3152	Membrane
KM395_16720	COG1151	hydroxylamine reductase activity
KM395_16730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_16735	COG3757	hydrolase, family 25
KM395_16735	COG3409	Peptidoglycan-binding domain 1 protein
KM395_16770	COG2072	flavoprotein involved in K transport
KM395_16805	COG0604	alcohol dehydrogenase
KM395_16810	COG1113	amino acid transport
KM395_16815	COG2814	Major facilitator Superfamily
KM395_16845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM395_16850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM395_16870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_16885	COG3739	integral membrane protein
KM395_16890	COG0384	phenazine biosynthesis protein PhzF
KM395_16920	COG0583	DNA-binding transcription factor activity
KM395_16940	COG1193	negative regulation of DNA recombination
KM395_16960	COG1164	Oligoendopeptidase f
KM395_16965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM395_16995	COG0584	glycerophosphoryl diester phosphodiesterase
KM395_17020	COG0640	Transcriptional regulator
KM395_17025	COG0604	alcohol dehydrogenase
KM395_17045	COG2808	Putative FMN-binding domain
KM395_17050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM395_17060	COG0385	Bile acid
KM395_17065	COG0277	FAD linked oxidase domain protein
KM395_17095	COG1216	Glycosyl transferase, family 2
KM395_17100	COG1024	Enoyl-CoA hydratase
KM395_17110	COG1285	pathogenesis
KM395_17125	COG2514	catechol 2,3-dioxygenase activity
KM395_17130	COG2720	vancomycin resistance protein
KM395_17170	COG0716	FMN binding
KM395_17200	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_17210	COG0165	Argininosuccinate lyase
KM395_17225	COG4145	pantothenate transmembrane transporter activity
KM395_17235	COG1012	belongs to the aldehyde dehydrogenase family
KM395_17240	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_17250	COG1657	PFAM Prenyltransferase squalene oxidase
KM395_17255	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM395_17260	COG2962	Rard protein
KM395_17265	COG3326	Membrane
KM395_17280	COG0489	protein tyrosine kinase activity
KM395_17290	COG0314	molybdopterin synthase activity
KM395_17295	COG0303	'Molybdopterin
KM395_17300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM395_17305	COG2116	formate transmembrane transporter activity
KM395_17315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM395_17320	COG5609	conserved protein (DUF2294)
KM395_17325	COG2427	Protein of unknown function (DUF1641)
KM395_17330	COG3383	formate dehydrogenase (NAD+) activity
KM395_17335	COG0697	spore germination
KM395_17375	COG2226	methyltransferase
KM395_17380	COG4166	transmembrane transport
KM395_17385	COG4166	transmembrane transport
KM395_17390	COG4166	transmembrane transport
KM395_17395	COG1301	dicarboxylic acid transport
KM395_17400	COG1316	TRANSCRIPTIONal
KM395_17410	COG1595	DNA-templated transcription, initiation
KM395_17430	COG1131	(ABC) transporter
KM395_17440	COG0673	inositol 2-dehydrogenase activity
KM395_17445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM395_17450	COG0187	DNA topoisomerase II activity
KM395_17455	COG1832	CoA-binding protein
KM395_17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM395_17465	COG0745	RESPONSE REGULATOR receiver
KM395_17480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM395_17485	COG4841	protein insertion into membrane
KM395_17490	COG0824	Thioesterase
KM395_17520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM395_17530	COG2274	protein secretion by the type I secretion system
KM395_17535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM395_17575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM395_17590	COG0183	Belongs to the thiolase family
KM395_17595	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_17600	COG1268	BioY protein
KM395_17605	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_17655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_17665	COG5002	protein histidine kinase activity
KM395_17670	COG0400	carboxylic ester hydrolase activity
KM395_17675	COG0346	lactoylglutathione lyase activity
KM395_17680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM395_17685	COG0069	glutamate synthase activity
KM395_17690	COG1902	pentaerythritol trinitrate reductase activity
KM395_17695	COG1329	Transcriptional regulator
KM395_17700	COG0010	Belongs to the arginase family
KM395_17725	COG2226	methyltransferase
KM395_17780	COG4846	Membrane protein involved in cytochrome C biogenesis
KM395_17785	COG0785	Cytochrome C biogenesis protein
KM395_17795	COG0583	DNA-binding transcription factor activity
KM395_17800	COG1380	Effector of murein hydrolase LrgA
KM395_17805	COG1346	cytolysis
KM395_17830	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM395_17830	COG3409	Peptidoglycan-binding domain 1 protein
KM395_17845	COG1132	(ABC) transporter
KM395_17850	COG1132	(ABC) transporter
KM395_17880	COG3639	organic phosphonate transmembrane transporter activity
KM395_17885	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM395_17905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM395_17925	COG1695	Transcriptional regulator
KM395_17960	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM395_17960	COG1388	LysM domain
KM395_17960	COG3409	Peptidoglycan-binding domain 1 protein
KM395_17965	COG4824	toxin secretion phage lysis holin
KM395_18120	COG1595	DNA-templated transcription, initiation
KM395_18165	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM395_18245	COG1396	sequence-specific DNA binding
KM395_18270	COG0174	glutamine synthetase
KM395_18275	COG0789	Transcriptional regulator
KM395_18280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM395_18290	COG2860	membrane
KM395_18300	COG0464	growth
KM395_18330	COG1388	LysM domain
KM395_18330	COG3584	3D domain protein
KM395_18335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM395_18335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM395_18335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM395_18340	COG1105	Belongs to the carbohydrate kinase PfkB family
KM395_18345	COG1349	DNA-binding transcription factor activity
KM395_18355	COG2322	membrane
KM395_18365	COG1113	amino acid transport
KM395_18380	COG1408	metallophosphoesterase
KM395_18385	COG2116	formate transmembrane transporter activity
KM395_18395	COG2217	Heavy metal translocating P-type atpase
KM395_18400	COG2608	mercury ion transmembrane transporter activity
KM395_18405	COG1937	Protein conserved in bacteria
KM395_18415	COG2819	hydrolase of the alpha beta superfamily
KM395_18420	COG1120	ATPase activity
KM395_18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_18440	COG0708	Exodeoxyribonuclease III
KM395_18445	COG2169	Transcriptional regulator
KM395_18450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM395_18455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM395_18465	COG2364	Membrane
KM395_18480	COG2267	carboxylic ester hydrolase activity
KM395_18485	COG0346	lactoylglutathione lyase activity
KM395_18490	COG3300	MHYT domain
KM395_18490	COG5001	Diguanylate cyclase
KM395_18505	COG1346	cytolysis
KM395_18510	COG1380	Effector of murein hydrolase LrgA
KM395_18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM395_18520	COG0596	Alpha beta hydrolase
KM395_18520	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM395_18525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM395_18545	COG1404	Belongs to the peptidase S8 family
KM395_18550	COG3773	Cell wall hydrolase
KM395_18555	COG0562	UDP-galactopyranose mutase
KM395_18560	COG1368	sulfuric ester hydrolase activity
KM395_18565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM395_18575	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM395_18600	COG1131	(ABC) transporter
KM395_18620	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM395_18625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM395_18630	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM395_18635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM395_18635	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM395_18645	COG2359	stage V sporulation protein S
KM395_18650	COG1692	metallophosphoesterase
KM395_18675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM395_18680	COG1426	Protein conserved in bacteria
KM395_18695	COG0300	oxidoreductase activity
KM395_18700	COG0612	Peptidase, M16
KM395_18705	COG0612	Peptidase, M16
KM395_18710	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM395_18720	COG3845	ABC transporter
KM395_18725	COG1744	ABC transporter substrate-binding protein PnrA-like
KM395_18730	COG2188	Transcriptional regulator
KM395_18735	COG1674	ftsk spoiiie
KM395_18745	COG0740	serine-type endopeptidase activity
KM395_18750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM395_18760	COG0527	aspartate kinase activity
KM395_18765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM395_18770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM395_18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM395_18780	COG1873	PFAM PRC-barrel domain
KM395_18785	COG0612	Peptidase, M16
KM395_18790	COG0726	polysaccharide deacetylase
KM395_18805	COG0196	riboflavin kinase activity
KM395_18810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM395_18820	COG1550	Protein conserved in bacteria
KM395_18830	COG1358	cellular component organization or biogenesis
KM395_18835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM395_18840	COG0195	Participates in both transcription termination and antitermination
KM395_18860	COG0750	zinc metalloprotease
KM395_18870	COG4589	Belongs to the CDS family
KM395_18875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM395_18885	COG0528	UMP kinase activity
KM395_18915	COG4974	Belongs to the 'phage' integrase family
KM395_18925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM395_18935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM395_18975	COG1837	Belongs to the UPF0109 family
KM395_18985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM395_18995	COG0552	protein localization to endoplasmic reticulum
KM395_19000	COG1196	nuclear chromosome segregation
KM395_19010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM395_19015	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_19020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM395_19035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM395_19040	COG1461	Dihydroxyacetone kinase
KM395_19045	COG1302	Protein conserved in bacteria
KM395_19060	COG1564	THIamine pyrophosphokinase
KM395_19065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM395_19070	COG1162	GTPase activity
KM395_19075	COG0515	serine threonine protein kinase
KM395_19075	COG2815	serine threonine protein kinase
KM395_19080	COG0631	protein serine/threonine phosphatase activity
KM395_19090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM395_19090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM395_19100	COG0242	peptide deformylase activity
KM395_19105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM395_19110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM395_19130	COG1561	YicC-like family, N-terminal region
KM395_19135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM395_19145	COG0006	proline dipeptidase activity
KM395_19160	COG3069	C4-dicarboxylate transmembrane transporter activity
KM395_19225	COG0564	pseudouridine synthase activity
KM395_19245	COG3599	regulation of cell shape
KM395_19250	COG2302	S4 RNA-binding domain
KM395_19255	COG0762	integral membrane protein
KM395_19265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM395_19270	COG1496	oxidoreductase activity
KM395_19275	COG1873	PFAM PRC-barrel domain
KM395_19280	COG1191	sigma factor activity
KM395_19285	COG1191	sigma factor activity
KM395_19295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM395_19300	COG0849	cell division
KM395_19305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM395_19310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM395_19320	COG0772	Belongs to the SEDS family
KM395_19335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM395_19340	COG0768	penicillin binding
KM395_19345	COG0768	penicillin binding
KM395_19350	COG4839	cell division protein FtsL
KM395_19365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM395_19380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM395_19385	COG1399	metal-binding, possibly nucleic acid-binding protein
KM395_19435	COG4824	toxin secretion phage lysis holin
KM395_19520	COG1802	Transcriptional regulator
KM395_19520	COG4626	Terminase
KM395_19545	COG0582	viral genome integration into host DNA
KM395_19610	COG0756	dUTP diphosphatase activity
KM395_19625	COG1191	sigma factor activity
KM395_19650	COG1484	DNA-dependent DNA replication
KM395_19680	COG1396	sequence-specific DNA binding
KM395_19695	COG1396	sequence-specific DNA binding
KM395_19710	COG0582	viral genome integration into host DNA
KM395_19720	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM395_19725	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM395_19730	COG3314	Sporulation integral membrane protein YlbJ
KM395_19740	COG0742	ribosomal rna small subunit methyltransferase
KM395_19755	COG3679	Belongs to the UPF0342 family
KM395_19760	COG0406	alpha-ribazole phosphatase activity
KM395_19775	COG2340	Cysteine-rich secretory protein family
KM395_19790	COG3336	cytochrome c oxidase
KM395_19825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM395_19830	COG0772	Belongs to the SEDS family
KM395_19840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM395_19845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM395_19855	COG4896	Protein conserved in bacteria
KM395_19870	COG1217	gtp-binding protein TYPA
KM395_19880	COG0483	inositol monophosphate 1-phosphatase activity
KM395_19900	COG1982	Orn Lys Arg decarboxylase major
KM395_19945	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM395_19950	COG0022	dehydrogenase e1 component
KM395_19955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM395_19965	COG0242	peptide deformylase activity
KM395_19970	COG0561	phosphatase activity
KM395_19980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM395_19985	COG0569	domain protein
KM395_20005	COG0583	DNA-binding transcription factor activity
KM395_20010	COG0517	IMP dehydrogenase activity
KM395_20020	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM395_20030	COG4703	Protein of unknown function (DUF1797)
KM395_20045	COG2200	EAL domain
KM395_20050	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_20055	COG1408	metallophosphoesterase
KM395_20065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM395_20100	COG2814	Major facilitator Superfamily
KM395_20120	COG3209	COG3209 Rhs family protein
KM395_20130	COG2205	protein histidine kinase activity
KM395_20140	COG0436	Aminotransferase
KM395_20145	COG1609	Transcriptional regulator
KM395_20150	COG3833	ABC-type maltose transport systems, permease component
KM395_20155	COG1175	transmembrane transport
KM395_20160	COG2182	Extracellular solute-binding protein
KM395_20170	COG0366	Alpha amylase catalytic
KM395_20175	COG3842	ATPase activity
KM395_20215	COG0183	Belongs to the thiolase family
KM395_20250	COG1695	Transcriptional regulator
KM395_20255	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_20265	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM395_20275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM395_20280	COG0436	Aminotransferase
KM395_20300	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM395_20320	COG2199	diguanylate cyclase activity
KM395_20325	COG0778	Nitroreductase
KM395_20350	COG2190	(PTS) system
KM395_20350	COG1263	PTS System
KM395_20350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM395_20355	COG3711	transcriptional antiterminator
KM395_20365	COG2188	Transcriptional regulator
KM395_20400	COG1547	Domain of unknown function (DUF309)
KM395_20405	COG0456	acetyltransferase
KM395_20410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM395_20415	COG4086	secreted protein
KM395_20420	COG0561	phosphatase activity
KM395_20425	COG0697	spore germination
KM395_20440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_20465	COG0733	neurotransmitter:sodium symporter activity
KM395_20485	COG1686	Belongs to the peptidase S11 family
KM395_20490	COG1725	Transcriptional regulator
KM395_20495	COG1131	(ABC) transporter
KM395_20510	COG1846	Transcriptional regulator
KM395_20525	COG0598	Magnesium transport protein CorA
KM395_20550	COG4974	Belongs to the 'phage' integrase family
KM395_20560	COG0735	belongs to the Fur family
KM395_20565	COG1300	Membrane
KM395_20585	COG0667	Aldo Keto reductase
KM395_20590	COG0656	L-ascorbic acid biosynthetic process
KM395_20595	COG0456	acetyltransferase
KM395_20595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM395_20605	COG4085	toxin activity
KM395_20605	COG1525	nuclease
KM395_20605	COG0737	Belongs to the 5'-nucleotidase family
KM395_20615	COG0596	Alpha beta hydrolase
KM395_20620	COG2056	Na+-H+ antiporter family
KM395_20625	COG1609	Transcriptional regulator
KM395_20630	COG0456	acetyltransferase
KM395_20635	COG1073	alpha beta
KM395_20650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM395_20650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM395_20655	COG0307	riboflavin synthase, alpha
KM395_20680	COG4106	trans-aconitate 2-methyltransferase activity
KM395_20685	COG1073	alpha beta
KM395_20685	COG2226	methyltransferase
KM395_20700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM395_20710	COG1757	Na H antiporter
KM395_20715	COG0737	Belongs to the 5'-nucleotidase family
KM395_20725	COG1522	sequence-specific DNA binding
KM395_20745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM395_20755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM395_20770	COG0300	oxidoreductase activity
KM395_20780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM395_20785	COG1760	l-serine dehydratase
KM395_20790	COG1760	l-serine dehydratase
KM395_20810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM395_20820	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM395_20825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_20840	COG1376	ErfK ybiS ycfS ynhG family protein
KM395_20845	COG4129	membrane
KM395_20850	COG1126	abc transporter atp-binding protein
KM395_20855	COG0765	amino acid transport
KM395_20860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM395_20880	COG0772	Belongs to the SEDS family
KM395_20885	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM395_20890	COG0022	dehydrogenase e1 component
KM395_20895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM395_20900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM395_20915	COG0280	phosphate acetyltransferase
KM395_20920	COG3829	transcription factor binding
KM395_20920	COG3290	protein histidine kinase activity
KM395_20930	COG0584	glycerophosphoryl diester phosphodiesterase
KM395_20935	COG3093	addiction module antidote protein HigA
KM395_20945	COG0745	RESPONSE REGULATOR receiver
KM395_20950	COG0750	zinc metalloprotease
KM395_20955	COG0497	DNA recombination
KM395_20965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM395_20975	COG0142	geranyltranstransferase activity
KM395_21000	COG1302	Protein conserved in bacteria
KM395_21005	COG0439	Biotin carboxylase
KM395_21010	COG0511	ligase activity, forming carbon-carbon bonds
KM395_21055	COG3854	ATPases associated with a variety of cellular activities
KM395_21080	COG0006	proline dipeptidase activity
KM395_21095	COG3872	metal-dependent enzyme
KM395_21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM395_21125	COG0095	Lipoate-protein ligase
KM395_21130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_21135	COG1609	Transcriptional regulator
KM395_21145	COG2076	Multidrug Resistance protein
KM395_21150	COG2076	Multidrug Resistance protein
KM395_21185	COG1131	(ABC) transporter
KM395_21190	COG1725	Transcriptional regulator
KM395_21220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM395_21275	COG4970	Tfp pilus assembly protein FimT
KM395_21285	COG1459	type II secretion system
KM395_21290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM395_21340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM395_21345	COG1410	methionine synthase
KM395_21345	COG0646	methionine synthase
KM395_21350	COG0646	methionine synthase
KM395_21350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM395_21355	COG0626	cystathionine gamma-synthase activity
KM395_21360	COG0626	cystathionine gamma-synthase activity
KM395_21380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_21390	COG1940	carbohydrate kinase activity
KM395_21395	COG4483	Protein conserved in bacteria
KM395_21400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM395_21405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM395_21415	COG0704	Plays a role in the regulation of phosphate uptake
KM395_21425	COG0581	inorganic phosphate transmembrane transporter activity
KM395_21430	COG0573	inorganic phosphate transmembrane transporter activity
KM395_21435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM395_21440	COG0768	penicillin binding
KM395_21445	COG0477	Major facilitator Superfamily
KM395_21450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM395_21475	COG0735	belongs to the Fur family
KM395_21480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM395_21485	COG1121	(ABC) transporter
KM395_21490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_21520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM395_21525	COG2384	SAM-dependent methyltransferase
KM395_21530	COG2010	Cytochrome c
KM395_21535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM395_21540	COG0358	DNA primase activity
KM395_21550	COG0517	IMP dehydrogenase activity
KM395_21565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM395_21570	COG0295	cytidine deaminase activity
KM395_21575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM395_21585	COG1480	7TM receptor with intracellular HD hydrolase
KM395_21590	COG1702	phosphate starvation-inducible protein PhoH
KM395_21605	COG1610	YqeY-like protein
KM395_21610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM395_21615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM395_21620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM395_21650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM395_21655	COG1733	regulation of RNA biosynthetic process
KM395_21680	COG1466	dna polymerase III delta subunit
KM395_21690	COG0658	competence protein
KM395_21690	COG2333	competence protein COMEC
KM395_21695	COG2131	deaminase
KM395_21700	COG1596	polysaccharide export
KM395_21700	COG1555	photosystem II stabilization
KM395_21705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM395_21710	COG2226	methyltransferase
KM395_21715	COG0799	negative regulation of ribosome biogenesis
KM395_21720	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM395_21730	COG1534	Rna-binding protein
KM395_21740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM395_21745	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM395_21770	COG1595	DNA-templated transcription, initiation
KM395_21780	COG0778	Nitroreductase
KM395_21785	COG2357	RelA SpoT domain protein
KM395_21795	COG1785	Belongs to the alkaline phosphatase family
KM395_21805	COG2267	carboxylic ester hydrolase activity
KM395_21840	COG1404	Belongs to the peptidase S8 family
KM395_21845	COG3186	Phenylalanine-4-hydroxylase
KM395_21860	COG2259	Doxx family
KM395_21900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_21910	COG1454	alcohol dehydrogenase
KM395_21910	COG1012	belongs to the aldehyde dehydrogenase family
KM395_21915	COG0626	cystathionine gamma-synthase activity
KM395_21920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM395_21945	COG0768	penicillin binding
KM395_21960	COG0826	peptidase U32
KM395_21965	COG0826	peptidase U32
KM395_21970	COG4122	O-methyltransferase activity
KM395_21975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM395_21995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM395_22005	COG0628	permease
KM395_22025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM395_22035	COG0482	sulfurtransferase activity
KM395_22040	COG1104	cysteine desulfurase activity
KM395_22045	COG1959	2 iron, 2 sulfur cluster binding
KM395_22050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM395_22060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM395_22085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM395_22095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM395_22095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM395_22100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM395_22105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM395_22105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM395_22115	COG2244	polysaccharide biosynthetic process
KM395_22120	COG2323	membrane
KM395_22130	COG1862	Preprotein translocase
KM395_22160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM395_22170	COG0697	spore germination
KM395_22175	COG0697	spore germination
KM395_22180	COG0640	Transcriptional regulator
KM395_22205	COG0157	Belongs to the NadC ModD family
KM395_22210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM395_22215	COG1104	cysteine desulfurase activity
KM395_22220	COG1827	regulation of RNA biosynthetic process
KM395_22225	COG2258	MOSC domain
KM395_22230	COG0077	Prephenate dehydratase
KM395_22235	COG0577	efflux transmembrane transporter activity
KM395_22240	COG0577	efflux transmembrane transporter activity
KM395_22245	COG1136	(ABC) transporter
KM395_22255	COG0745	RESPONSE REGULATOR receiver
KM395_22260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM395_22265	COG3290	protein histidine kinase activity
KM395_22275	COG2868	ribosomal protein
KM395_22285	COG1530	ribonuclease E activity
KM395_22290	COG1994	Peptidase M50
KM395_22295	COG0739	heme binding
KM395_22300	COG2894	cell division
KM395_22320	COG1077	Cell shape determining protein MreB Mrl
KM395_22340	COG0285	dihydrofolate synthase activity
KM395_22345	COG0525	valine-tRNA ligase activity
KM395_22355	COG1388	LysM domain
KM395_22365	COG0113	porphobilinogen synthase activity
KM395_22370	COG1587	Uroporphyrinogen-III synthase
KM395_22380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM395_22390	COG1846	Transcriptional regulator
KM395_22395	COG1764	response to oxidative stress
KM395_22410	COG1067	ATP-dependent peptidase activity
KM395_22410	COG0470	DNA polymerase III
KM395_22455	COG0622	Phosphoesterase
KM395_22470	COG5401	PFAM Sporulation and spore germination
KM395_22490	COG1309	transcriptional regulator
KM395_22505	COG2197	response regulator
KM395_22510	COG2233	PERMEase
KM395_22520	COG0402	S-adenosylhomocysteine deaminase activity
KM395_22525	COG0402	S-adenosylhomocysteine deaminase activity
KM395_22535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM395_22545	COG0444	Belongs to the ABC transporter superfamily
KM395_22550	COG4608	Belongs to the ABC transporter superfamily
KM395_22555	COG3275	phosphorelay sensor kinase activity
KM395_22560	COG3279	Response regulator of the LytR AlgR family
KM395_22575	COG1983	PspC domain protein
KM395_22580	COG1396	sequence-specific DNA binding
KM395_22585	COG0697	spore germination
KM395_22595	COG1959	2 iron, 2 sulfur cluster binding
KM395_22600	COG1668	transmembrane transport
KM395_22605	COG4152	abc transporter atp-binding protein
KM395_22610	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM395_22620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM395_22625	COG1876	peptidase activity
KM395_22630	COG0824	Thioesterase
KM395_22635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM395_22640	COG1053	succinate dehydrogenase
KM395_22645	COG2009	succinate dehydrogenase
KM395_22650	COG1719	4-vinyl reductase, 4VR
KM395_22660	COG3118	belongs to the thioredoxin family
KM395_22665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM395_22670	COG2086	electron transfer activity
KM395_22675	COG1024	Enoyl-CoA hydratase
KM395_22680	COG1309	transcriptional regulator
KM395_22685	COG0318	PFAM AMP-dependent synthetase and ligase
KM395_22705	COG2318	DinB family
KM395_22735	COG1131	(ABC) transporter
KM395_22740	COG2205	protein histidine kinase activity
KM395_22745	COG0745	RESPONSE REGULATOR receiver
KM395_22755	COG4895	conserved protein (DUF2196)
KM395_22760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM395_22775	COG4509	Sortase family
KM395_22780	COG1120	ATPase activity
KM395_22795	COG5386	Cell surface protein
KM395_22805	COG5386	Cell surface protein
KM395_22810	COG1114	Component of the transport system for branched-chain amino acids
KM395_22815	COG1187	pseudouridine synthase activity
KM395_22825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM395_22825	COG1796	DNA polymerase
KM395_22830	COG1286	toxin biosynthetic process
KM395_22875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM395_22885	COG1418	mRNA catabolic process
KM395_22910	COG2814	Major facilitator Superfamily
KM395_22915	COG1566	PFAM secretion protein HlyD family protein
KM395_22920	COG1309	transcriptional regulator
KM395_22925	COG1363	Peptidase, m42
KM395_22950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM395_22960	COG1484	DNA-dependent DNA replication
KM395_22965	COG3611	Membrane attachment protein
KM395_22975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM395_22980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM395_22985	COG0237	dephospho-CoA kinase activity
KM395_22990	COG1971	Probably functions as a manganese efflux pump
KM395_23000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM395_23000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM395_23005	COG5002	protein histidine kinase activity
KM395_23010	COG0745	RESPONSE REGULATOR receiver
KM395_23030	COG0538	isocitrate dehydrogenase activity
KM395_23035	COG0372	Belongs to the citrate synthase family
KM395_23045	COG0628	permease
KM395_23050	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM395_23075	COG1725	Transcriptional regulator
KM395_23080	COG0281	malic enzyme
KM395_23085	COG0587	DNA-directed DNA polymerase activity
KM395_23100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM395_23120	COG4109	DRTGG domain
KM395_23135	COG0006	proline dipeptidase activity
KM395_23170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_23175	COG0662	Cupin 2, conserved barrel domain protein
KM395_23185	COG1476	TRANSCRIPTIONal
KM395_23200	COG1028	Short-chain dehydrogenase reductase Sdr
KM395_23205	COG0589	response to stress
KM395_23245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_23265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM395_23270	COG0827	DNA restriction-modification system
KM395_23275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM395_23280	COG3874	Sporulation protein YtfJ
KM395_23295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM395_23305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM395_23320	COG1104	cysteine desulfurase activity
KM395_23330	COG0583	DNA-binding transcription factor activity
KM395_23335	COG0697	spore germination
KM395_23345	COG1956	GAF domain-containing protein
KM395_23350	COG0626	cystathionine gamma-synthase activity
KM395_23380	COG1595	DNA-templated transcription, initiation
KM395_23390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM395_23395	COG0454	-acetyltransferase
KM395_23400	COG0517	IMP dehydrogenase activity
KM395_23405	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM395_23415	COG0745	RESPONSE REGULATOR receiver
KM395_23425	COG0666	response to abiotic stimulus
KM395_23460	COG1609	Transcriptional regulator
KM395_23465	COG4851	CamS sex pheromone cAM373 precursor
KM395_23470	COG3118	belongs to the thioredoxin family
KM395_23480	COG2309	aminopeptidase activity
KM395_23500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_23515	COG1674	ftsk spoiiie
KM395_23525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM395_23530	COG4848	Belongs to the UPF0354 family
KM395_23535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM395_23540	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM395_23545	COG1363	Peptidase, m42
KM395_23555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_23570	COG0510	thiamine kinase activity
KM395_23575	COG1523	belongs to the glycosyl hydrolase 13 family
KM395_23590	COG1349	DNA-binding transcription factor activity
KM395_23595	COG1187	pseudouridine synthase activity
KM395_23600	COG2244	polysaccharide biosynthetic process
KM395_23605	COG2081	HI0933 family
KM395_23610	COG2814	Major facilitator Superfamily
KM395_23620	COG3832	glyoxalase III activity
KM395_23640	COG1329	Transcriptional regulator
KM395_23650	COG4975	Glucose uptake
KM395_23665	COG0314	molybdopterin synthase activity
KM395_23670	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM395_23675	COG0303	'Molybdopterin
KM395_23685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM395_23710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM395_23720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM395_23760	COG2814	Major facilitator Superfamily
KM395_23765	COG0475	glutathione-regulated potassium exporter activity
KM395_23770	COG0490	domain, Protein
KM395_23775	COG0582	viral genome integration into host DNA
KM395_23785	COG1136	(ABC) transporter
KM395_23805	COG1242	4 iron, 4 sulfur cluster binding
KM395_23810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM395_23815	COG1131	(ABC) transporter
KM395_23825	COG1794	racemase activity, acting on amino acids and derivatives
KM395_23845	COG2267	carboxylic ester hydrolase activity
KM395_23850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM395_23855	COG0671	phosphoesterase, PA-phosphatase related
KM395_23860	COG0438	transferase activity, transferring glycosyl groups
KM395_23870	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM395_23925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM395_23930	COG5002	protein histidine kinase activity
KM395_23935	COG4191	Histidine kinase
KM395_23940	COG2267	carboxylic ester hydrolase activity
KM395_23960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM395_23965	COG1116	anion transmembrane transporter activity
KM395_23970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM395_23995	COG0494	nUDIX hydrolase
KM395_24025	COG0288	reversible hydration of carbon dioxide
KM395_24030	COG1271	oxidase subunit
KM395_24035	COG1294	oxidase, subunit
KM395_24055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_24080	COG1842	Phage shock protein A
KM395_24110	COG5002	protein histidine kinase activity
KM395_24115	COG0745	RESPONSE REGULATOR receiver
KM395_24145	COG1597	lipid kinase activity
KM395_24180	COG0586	Pfam SNARE associated Golgi protein
KM395_24190	COG0577	efflux transmembrane transporter activity
KM395_24195	COG1136	(ABC) transporter
KM395_24200	COG2207	Transcriptional regulator
KM395_24200	COG3708	Transcriptional regulator
KM395_24205	COG0745	RESPONSE REGULATOR receiver
KM395_24210	COG2205	protein histidine kinase activity
KM395_24220	COG0577	efflux transmembrane transporter activity
KM395_24225	COG1136	(ABC) transporter
KM395_24245	COG2188	Transcriptional regulator
KM395_24265	COG3964	amidohydrolase
KM395_24295	COG4948	Mandelate Racemase Muconate Lactonizing
KM395_24305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM395_24310	COG0596	Alpha beta hydrolase
KM395_24315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM395_24320	COG1169	isochorismate synthase
KM395_24325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM395_24330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM395_24350	COG0058	SHG alpha-glucan phosphorylase activity
KM395_24355	COG0297	glycogen (starch) synthase activity
KM395_24360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM395_24480	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM395_24515	COG1285	pathogenesis
KM395_24520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM395_24530	COG0166	Belongs to the GPI family
KM395_24535	COG2155	Conserved Protein
KM395_24540	COG1098	S1 RNA binding domain
KM395_24545	COG0436	Aminotransferase
KM395_24550	COG1522	sequence-specific DNA binding
KM395_24555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM395_24560	COG2267	carboxylic ester hydrolase activity
KM395_24570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM395_24590	COG5018	Exonuclease
KM395_24595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM395_24615	COG2050	protein possibly involved in aromatic compounds catabolism
KM395_24625	COG1268	BioY protein
KM395_24635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM395_24640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM395_24655	COG3584	3D domain protein
KM395_24670	COG1252	NADH dehydrogenase
KM395_24685	COG3708	Transcriptional regulator
KM395_24700	COG1683	Conserved Protein
KM395_24720	COG0316	Belongs to the HesB IscA family
KM395_24735	COG1252	NADH dehydrogenase
KM395_24750	COG0390	transport system, permease component
KM395_24755	COG2824	Alkylphosphonate utilization operon protein PhnA
KM395_24795	COG4837	Protein of unknown function (DUF1462)
KM395_24800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM395_24810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM395_24815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM395_24825	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM395_24830	COG0647	UMP catabolic process
KM395_24840	COG2445	Protein of unknown function DUF86
KM395_24845	COG1494	fructose-1,6-bisphosphatase
KM395_24860	COG4470	Protein conserved in bacteria
KM395_24870	COG0789	Transcriptional regulator
KM395_24875	COG4377	Putative membrane peptidase family (DUF2324)
KM395_24900	COG0739	heme binding
KM395_24910	COG3377	Domain of unknown function (DUF1805)
KM395_24915	COG0737	Belongs to the 5'-nucleotidase family
KM395_24920	COG1695	Transcriptional regulator
KM395_24930	COG0719	Fe-S assembly protein
KM395_24935	COG0822	iron-sulfur transferase activity
KM395_24940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM395_24945	COG0719	Fe-S assembly protein
KM395_24950	COG0396	ATPase activity
KM395_24955	COG1464	Belongs to the NlpA lipoprotein family
KM395_24960	COG1464	Belongs to the NlpA lipoprotein family
KM395_24965	COG2011	ABC-type metal ion transport system permease component
KM395_24970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM395_24980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM395_24985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM395_24995	COG1393	Belongs to the ArsC family
KM395_25040	COG0039	L-malate dehydrogenase activity
KM395_25060	COG1309	transcriptional regulator
KM395_25065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM395_25070	COG1960	acyl-CoA dehydrogenase activity
KM395_25075	COG0183	Belongs to the thiolase family
KM395_25080	COG1024	Enoyl-CoA hydratase
KM395_25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM395_25090	COG1686	Belongs to the peptidase S11 family
KM395_25105	COG0011	TIGRFAM Protein of
KM395_25110	COG0840	transmembrane signaling receptor activity
KM395_25130	COG2814	Major facilitator Superfamily
KM395_25135	COG0531	amino acid
KM395_25145	COG0706	membrane insertase activity
KM395_25155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM395_25190	COG0586	Pfam SNARE associated Golgi protein
KM395_25200	COG1376	ErfK ybiS ycfS ynhG family protein
KM395_25205	COG0745	RESPONSE REGULATOR receiver
KM395_25210	COG5002	protein histidine kinase activity
KM395_25235	COG2151	metal-sulfur cluster biosynthetic enzyme
KM395_25240	COG3227	Zinc metalloprotease (Elastase)
KM395_25245	COG1741	Belongs to the pirin family
KM395_25260	COG0475	glutathione-regulated potassium exporter activity
KM395_25265	COG0490	domain, Protein
KM395_25270	COG1115	amino acid carrier protein
KM395_25275	COG0783	Belongs to the Dps family
KM395_25290	COG1611	Belongs to the LOG family
KM395_25310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_25320	COG1115	amino acid carrier protein
KM395_25325	COG1115	amino acid carrier protein
KM395_25330	COG2910	NAD(P)H-binding
KM395_25345	COG0656	L-ascorbic acid biosynthetic process
KM395_25350	COG2814	Major facilitator Superfamily
KM395_25355	COG1733	regulation of RNA biosynthetic process
KM395_25365	COG1252	NADH dehydrogenase
KM395_25370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM395_25375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM395_25385	COG3290	protein histidine kinase activity
KM395_25385	COG0840	transmembrane signaling receptor activity
KM395_25395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM395_25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM395_25415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM395_25470	COG0557	exoribonuclease II activity
KM395_25475	COG1647	Serine aminopeptidase, S33
KM395_25480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM395_25485	COG1346	cytolysis
KM395_25585	COG4695	Portal protein
KM395_25610	COG4974	Belongs to the 'phage' integrase family
KM395_25620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM395_25625	COG0149	triose-phosphate isomerase activity
KM395_25635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM395_25650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM395_25675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM395_25690	COG2323	membrane
KM395_25695	COG0740	serine-type endopeptidase activity
KM395_25700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM395_25710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM395_25720	COG1051	belongs to the nudix hydrolase family
KM395_25730	COG0492	ferredoxin-NADP+ reductase activity
KM395_25735	COG0457	Tetratricopeptide repeat
KM395_25740	COG0110	maltose O-acetyltransferase activity
KM395_25760	COG1950	PFAM Membrane protein of
KM395_25770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM395_25775	COG0556	nucleotide-excision repair
KM395_25795	COG0789	Transcriptional regulator
KM395_25820	COG2855	membrane
KM395_25825	COG0583	DNA-binding transcription factor activity
KM395_25835	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM395_25840	COG0488	(ABC) transporter
KM395_25850	COG1132	(ABC) transporter
KM395_25855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM395_25860	COG0793	Belongs to the peptidase S41A family
KM395_25860	COG3409	Peptidoglycan-binding domain 1 protein
KM395_25865	COG2177	Part of the ABC transporter FtsEX involved in
KM395_25870	COG2884	Cell division ATP-binding protein ftsE
KM395_25885	COG0653	protein targeting
KM395_25890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM395_25895	COG1278	Cold shock
KM395_25900	COG1040	competence protein
KM395_25905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM395_25910	COG0791	NLP P60 protein
KM395_25910	COG1388	LysM domain
KM395_25915	COG1733	regulation of RNA biosynthetic process
KM395_25920	COG1307	EDD domain protein, DegV family
KM395_25925	COG1739	Uncharacterized protein family UPF0029
KM395_25930	COG1316	TRANSCRIPTIONal
KM395_25935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM395_25940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM395_25945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM395_25955	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM395_25955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM395_25970	COG3394	polysaccharide catabolic process
KM395_25975	COG1486	melibiose metabolic process
KM395_25980	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM395_25985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM395_25995	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM395_26000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM395_26005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM395_26015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM395_26020	COG1301	dicarboxylic acid transport
KM395_26030	COG0346	lactoylglutathione lyase activity
KM395_26035	COG1511	domain protein
KM395_26040	COG0583	DNA-binding transcription factor activity
KM395_26045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM395_26060	COG1271	oxidase subunit
KM395_26065	COG1294	oxidase, subunit
KM395_26070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM395_26090	COG2389	metal-binding protein
KM395_26100	COG1368	sulfuric ester hydrolase activity
KM395_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM395_26125	COG1215	transferase activity, transferring glycosyl groups
KM395_26130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM395_26135	COG3584	3D domain protein
KM395_26135	COG1388	LysM domain
KM395_26160	COG4715	Zinc finger, swim domain protein
KM395_26165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM395_26205	COG0577	efflux transmembrane transporter activity
KM395_26210	COG1136	(ABC) transporter
KM395_26245	COG5002	protein histidine kinase activity
KM395_26250	COG0745	RESPONSE REGULATOR receiver
KM395_26255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM395_26270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM395_26275	COG1134	teichoic acid transport
KM395_26280	COG1682	transport, permease protein
KM395_26285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM395_26330	COG1609	Transcriptional regulator
KM395_26345	COG0739	heme binding
KM395_26365	COG2385	sporulation resulting in formation of a cellular spore
KM395_26380	COG4836	Membrane
KM395_26385	COG1007	ATP synthesis coupled electron transport
KM395_26390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM395_26395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM395_26405	COG0839	Belongs to the complex I subunit 6 family
KM395_26420	COG0649	NAD binding
KM395_26425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM395_26440	COG3300	MHYT domain
KM395_26440	COG5001	Diguanylate cyclase
KM395_26490	COG0356	it plays a direct role in the translocation of protons across the membrane
KM395_26525	COG0698	ribose 5-phosphate isomerase
KM395_26535	COG2190	(PTS) system
KM395_26540	COG2259	Doxx family
KM395_26545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM395_26560	COG0009	L-threonylcarbamoyladenylate synthase
KM395_26575	COG2890	protein-(glutamine-N5) methyltransferase activity
KM395_26595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM395_26600	COG1494	fructose-1,6-bisphosphatase
KM395_26620	COG4821	SIS domain
KM395_26630	COG3343	RNA polymerase activity
KM395_26640	COG1960	acyl-CoA dehydrogenase activity
KM395_26645	COG1960	acyl-CoA dehydrogenase activity
KM395_26650	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM395_26655	COG0183	Belongs to the thiolase family
KM395_26660	COG0247	lactate metabolic process
KM395_26660	COG2181	nitrate reductase activity
KM395_26665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM395_26675	COG5001	Diguanylate cyclase
KM395_26675	COG3300	MHYT domain
KM395_26695	COG2197	response regulator
KM395_26700	COG4585	Histidine kinase
KM395_26705	COG0842	Transport permease protein
KM395_26710	COG1131	(ABC) transporter
KM395_26715	COG0024	Methionine aminopeptidase
KM395_26725	COG2234	aminopeptidase activity
KM395_26745	COG1595	DNA-templated transcription, initiation
KM395_26750	COG0018	arginyl-trna synthetase
KM395_26755	COG4506	Protein conserved in bacteria
KM395_26760	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM395_26775	COG0010	Belongs to the arginase family
KM395_26785	COG2814	Major facilitator Superfamily
KM395_26790	COG0789	Transcriptional regulator
KM395_26795	COG0584	glycerophosphoryl diester phosphodiesterase
KM395_26800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM395_26810	COG1994	Peptidase M50
KM395_26820	COG1078	dGTPase activity
KM395_26825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM395_26830	COG1120	ATPase activity
KM395_26835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM395_26860	COG0095	Lipoate-protein ligase
KM395_26865	COG0280	phosphate acetyltransferase
KM395_26880	COG3773	Cell wall hydrolase
KM395_26890	COG2363	Small membrane protein
KM395_26900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM395_26905	COG2233	PERMEase
KM395_26910	COG0561	phosphatase activity
KM395_26915	COG2814	Major facilitator Superfamily
KM395_26925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM395_26930	COG1131	(ABC) transporter
KM395_26935	COG2755	lipolytic protein G-D-S-L family
KM395_26940	COG1609	Transcriptional regulator
KM395_26950	COG0460	homoserine dehydrogenase
KM395_26960	COG2873	o-acetylhomoserine
KM395_26970	COG1011	Hydrolase
KM395_26975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM395_26985	COG2197	response regulator
KM395_26995	COG0351	phosphomethylpyrimidine kinase
KM395_27000	COG3706	GGDEF domain
KM395_27005	COG2879	small protein
KM395_27010	COG1966	Carbon starvation protein
KM395_27015	COG3279	Response regulator of the LytR AlgR family
KM395_27020	COG0477	Major facilitator Superfamily
KM395_27045	COG0840	transmembrane signaling receptor activity
KM395_27055	COG1607	acyl-coa hydrolase
KM395_27070	COG0488	(ABC) transporter
KM395_27090	COG0463	Glycosyl transferase, family 2
KM395_27095	COG1309	transcriptional regulator
KM395_27100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM395_27105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM395_27105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM395_27110	COG0628	permease
KM395_27125	COG3279	Response regulator of the LytR AlgR family
KM395_27130	COG3275	phosphorelay sensor kinase activity
KM395_27135	COG2814	Major facilitator Superfamily
KM395_27140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM395_27145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM395_27150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM395_27170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM395_27175	COG1272	protein, Hemolysin III
KM395_27195	COG0516	GMP reductase activity
KM395_27200	COG1164	Oligoendopeptidase f
KM395_27220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM395_27225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM395_27230	COG4853	Protein conserved in bacteria
KM395_27235	COG4863	YycH protein
KM395_27240	COG5002	protein histidine kinase activity
KM395_27245	COG0745	RESPONSE REGULATOR receiver
KM395_27275	COG0305	Participates in initiation and elongation during chromosome replication
KM395_27285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM395_27290	COG4241	membrane
KM395_27300	COG0629	single-stranded DNA binding
KM395_27310	COG0012	GTP binding
KM395_27315	COG4481	Protein conserved in bacteria
KM395_27320	COG0668	transmembrane transport
KM395_27330	COG1475	DNA binding
KM395_27335	COG1192	Involved in chromosome partitioning
KM395_27360	COG1847	R3H domain protein
KM395_27365	COG0706	membrane insertase activity
KM395_27375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM395_27425	COG3344	reverse transcriptase
KM395_27505	COG3344	reverse transcriptase
KM395_27695	COG4962	Type ii secretion system protein e
KM395_27830	COG2311	Membrane
KM395_27850	COG4196	transglutaminase domain protein
KM395_27855	COG0671	phosphoesterase, PA-phosphatase related
KM395_27870	COG1215	transferase activity, transferring glycosyl groups
KM395_27875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM395_27880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM395_28035	COG2002	toxin-antitoxin pair type II binding
KM395_28045	COG4974	Belongs to the 'phage' integrase family
KM395_28100	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM395_28110	COG4974	Belongs to the 'phage' integrase family
KM395_28135	COG0457	Tetratricopeptide repeat
KM395_28340	COG0791	NLP P60 protein
KM395_28340	COG0741	lytic transglycosylase activity
KM395_28405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM395_28465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM395_28475	COG4166	transmembrane transport
KM395_28515	COG1280	lysine exporter protein (LysE YggA)
KM395_28540	COG0681	Belongs to the peptidase S26 family
KM395_28615	COG1309	transcriptional regulator
KM395_28620	COG1683	Conserved Protein
KM395_28660	COG1192	Involved in chromosome partitioning