locus-tag	class	description
BF39_100	COG5002	protein histidine kinase activity
BF39_1004	COG1253	flavin adenine dinucleotide binding
BF39_1005	COG1012	belongs to the aldehyde dehydrogenase family
BF39_1006	COG5506	Protein of unknown function (DUF1694)
BF39_1009	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_1010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF39_1011	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF39_1012	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_1013	COG0456	acetyltransferase
BF39_1014	COG3829	transcription factor binding
BF39_1015	COG1509	lysine 2,3-aminomutase activity
BF39_102	COG0720	synthase
BF39_1023	COG4326	sporulation control protein
BF39_1024	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF39_1025	COG0671	phosphoesterase, PA-phosphatase related
BF39_1026	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_1031	COG1715	Restriction endonuclease
BF39_1031	COG1787	Restriction endonuclease
BF39_1047	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_105	COG4873	Protein conserved in bacteria
BF39_1057	COG2814	Major facilitator Superfamily
BF39_1058	COG4841	protein insertion into membrane
BF39_1059	COG0372	Belongs to the citrate synthase family
BF39_1060	COG2079	MmgE PrpD family protein
BF39_1061	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF39_1062	COG1960	acyl-CoA dehydrogenase activity
BF39_1063	COG2084	Dehydrogenase
BF39_1064	COG1012	belongs to the aldehyde dehydrogenase family
BF39_1065	COG1280	lysine exporter protein (LysE YggA)
BF39_1066	COG1024	Enoyl-CoA hydratase
BF39_1069	COG0420	3'-5' exonuclease activity
BF39_1070	COG0419	ATPase involved in DNA repair
BF39_1074	COG2223	nitrite transmembrane transporter activity
BF39_1075	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_1076	COG1169	isochorismate synthase
BF39_1077	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF39_1078	COG1535	isochorismatase
BF39_1078	COG3433	isochorismatase activity
BF39_1079	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF39_1080	COG3251	PFAM MbtH domain protein
BF39_1081	COG2814	Major facilitator Superfamily
BF39_1084	COG0776	regulation of translation
BF39_1086	COG2318	DinB family
BF39_1088	COG1115	amino acid carrier protein
BF39_1091	COG2329	Antibiotic biosynthesis monooxygenase
BF39_1092	COG1187	pseudouridine synthase activity
BF39_1093	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_1098	COG0596	Alpha beta hydrolase
BF39_1099	COG2814	Major facilitator Superfamily
BF39_1104	COG2226	methyltransferase
BF39_1113	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_112	COG1780	Probably involved in ribonucleotide reductase function
BF39_1120	COG1247	-acetyltransferase
BF39_1128	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_113	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF39_1130	COG1278	Cold shock
BF39_1133	COG0010	Belongs to the arginase family
BF39_1134	COG0561	phosphatase activity
BF39_1142	COG0583	DNA-binding transcription factor activity
BF39_1143	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF39_1146	COG0583	DNA-binding transcription factor activity
BF39_1147	COG2258	MOSC domain
BF39_115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF39_1150	COG1132	(ABC) transporter
BF39_1151	COG1132	(ABC) transporter
BF39_1155	COG1396	sequence-specific DNA binding
BF39_116	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF39_1160	COG1595	DNA-templated transcription, initiation
BF39_1165	COG1649	PFAM Uncharacterised BCR, COG1649
BF39_117	COG1725	Transcriptional regulator
BF39_1170	COG2971	BadF BadG BcrA BcrD
BF39_1171	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_1172	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF39_1175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_118	COG1131	(ABC) transporter
BF39_1180	COG1309	transcriptional regulator
BF39_1183	COG1136	(ABC) transporter
BF39_1183	COG0577	efflux transmembrane transporter activity
BF39_1184	COG3615	Tellurite resistance protein tehB
BF39_1184	COG0500	methyltransferase
BF39_1186	COG2226	methyltransferase
BF39_1187	COG3961	Belongs to the TPP enzyme family
BF39_1188	COG1846	Transcriptional regulator
BF39_1196	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF39_120	COG1131	(ABC) transporter
BF39_1200	COG1595	DNA-templated transcription, initiation
BF39_1202	COG0768	penicillin binding
BF39_1205	COG2367	Beta-lactamase
BF39_1206	COG0671	phosphoesterase, PA-phosphatase related
BF39_1207	COG1609	Transcriptional regulator
BF39_1208	COG2814	Major facilitator Superfamily
BF39_1209	COG0673	inositol 2-dehydrogenase activity
BF39_121	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_1211	COG1012	belongs to the aldehyde dehydrogenase family
BF39_1215	COG3718	enzyme involved in inositol metabolism
BF39_1219	COG0737	Belongs to the 5'-nucleotidase family
BF39_1220	COG0737	Belongs to the 5'-nucleotidase family
BF39_1222	COG0457	Tetratricopeptide repeat
BF39_1223	COG1476	TRANSCRIPTIONal
BF39_1226	COG1876	peptidase activity
BF39_1231	COG1309	transcriptional regulator
BF39_1235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_1237	COG1252	NADH dehydrogenase
BF39_1238	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_124	COG1522	sequence-specific DNA binding
BF39_1241	COG1131	(ABC) transporter
BF39_1246	COG1960	acyl-CoA dehydrogenase activity
BF39_1247	COG0439	Biotin carboxylase
BF39_1248	COG0511	ligase activity, forming carbon-carbon bonds
BF39_1249	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF39_1250	COG1024	Enoyl-CoA hydratase
BF39_1251	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF39_1252	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_1254	COG1247	-acetyltransferase
BF39_1255	COG0572	uridine kinase
BF39_1257	COG2318	DinB family
BF39_1258	COG1686	Belongs to the peptidase S11 family
BF39_126	COG1335	isochorismatase
BF39_1263	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF39_1267	COG3227	Zinc metalloprotease (Elastase)
BF39_1272	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_1272	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_1275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_1277	COG2814	Major facilitator Superfamily
BF39_128	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_1281	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_1285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_1287	COG1063	alcohol dehydrogenase
BF39_129	COG2070	2-Nitropropane dioxygenase
BF39_1290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_1291	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_1294	COG3773	Cell wall hydrolase
BF39_1296	COG0745	RESPONSE REGULATOR receiver
BF39_1298	COG2205	protein histidine kinase activity
BF39_130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF39_1303	COG1136	(ABC) transporter
BF39_1304	COG0577	efflux transmembrane transporter activity
BF39_1305	COG0577	efflux transmembrane transporter activity
BF39_1309	COG0460	homoserine dehydrogenase
BF39_1310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_1312	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF39_132	COG1696	Membrane protein involved in D-alanine export
BF39_1328	COG2124	cytochrome p450
BF39_1335	COG0561	phosphatase activity
BF39_1337	COG5002	protein histidine kinase activity
BF39_1339	COG1819	glycosyl
BF39_1340	COG1794	racemase activity, acting on amino acids and derivatives
BF39_1342	COG1122	ATPase activity
BF39_1345	COG2205	protein histidine kinase activity
BF39_1348	COG0604	alcohol dehydrogenase
BF39_1358	COG0693	protein deglycase activity
BF39_1363	COG2814	Major facilitator Superfamily
BF39_1367	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_137	COG0716	FMN binding
BF39_1370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_1371	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_1372	COG0697	spore germination
BF39_1379	COG2223	nitrite transmembrane transporter activity
BF39_1381	COG2816	NAD+ diphosphatase activity
BF39_1382	COG0592	DNA-directed DNA polymerase activity
BF39_1383	COG1051	belongs to the nudix hydrolase family
BF39_1390	COG3878	Protein conserved in bacteria
BF39_1396	COG4667	esterase of the alpha-beta hydrolase superfamily
BF39_140	COG3173	Aminoglycoside phosphotransferase
BF39_1402	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF39_1405	COG0322	excinuclease ABC activity
BF39_1413	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_1418	COG1011	Hydrolase
BF39_1423	COG0076	glutamate decarboxylase activity
BF39_1426	COG1523	belongs to the glycosyl hydrolase 13 family
BF39_1427	COG3227	Zinc metalloprotease (Elastase)
BF39_1431	COG0201	protein transport
BF39_1433	COG0697	spore germination
BF39_1434	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_144	COG0534	Mate efflux family protein
BF39_1440	COG4129	membrane
BF39_1441	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_1444	COG2959	enzyme of heme biosynthesis
BF39_1445	COG3773	Cell wall hydrolase
BF39_1445	COG3409	Peptidoglycan-binding domain 1 protein
BF39_1448	COG3483	tryptophan 2,3-dioxygenase activity
BF39_1449	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF39_145	COG1968	undecaprenyl-diphosphatase activity
BF39_1450	COG3844	kynureninase activity
BF39_1451	COG1309	transcriptional regulator
BF39_1457	COG3284	Transcriptional regulator
BF39_1461	COG1349	DNA-binding transcription factor activity
BF39_1465	COG1959	2 iron, 2 sulfur cluster binding
BF39_1469	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF39_1470	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_1471	COG0022	dehydrogenase e1 component
BF39_1472	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_1474	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_1475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_1475	COG0456	acetyltransferase
BF39_148	COG1846	Transcriptional regulator
BF39_1481	COG4176	ABC-type proline glycine betaine transport system permease component
BF39_1482	COG4175	Glycine betaine
BF39_1482	COG0517	IMP dehydrogenase activity
BF39_1484	COG0740	serine-type endopeptidase activity
BF39_1487	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF39_1488	COG2153	protein acetylation
BF39_1489	COG3397	chitin binding
BF39_1493	COG2205	protein histidine kinase activity
BF39_1498	COG0658	competence protein
BF39_1498	COG2333	competence protein COMEC
BF39_150	COG1301	dicarboxylic acid transport
BF39_1508	COG3973	AAA domain
BF39_151	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF39_1511	COG2105	PFAM AIG2 family protein
BF39_1512	COG0514	ATP-dependent DNA helicase (RecQ)
BF39_1516	COG4637	Psort location Cytoplasmic, score
BF39_152	COG4709	membrane
BF39_1521	COG3397	chitin binding
BF39_1523	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF39_1524	COG1115	amino acid carrier protein
BF39_1525	COG1012	belongs to the aldehyde dehydrogenase family
BF39_1526	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF39_1528	COG3938	Belongs to the proline racemase family
BF39_1529	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_153	COG3874	Sporulation protein YtfJ
BF39_1536	COG0586	Pfam SNARE associated Golgi protein
BF39_1539	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF39_1540	COG0519	Catalyzes the synthesis of GMP from XMP
BF39_1541	COG4166	transmembrane transport
BF39_1543	COG4948	Mandelate Racemase Muconate Lactonizing
BF39_1551	COG2936	dipeptidyl-peptidase activity
BF39_1552	COG5002	protein histidine kinase activity
BF39_1553	COG0745	RESPONSE REGULATOR receiver
BF39_1560	COG1164	Oligoendopeptidase f
BF39_1563	COG1307	EDD domain protein, DegV family
BF39_1567	COG2814	Major facilitator Superfamily
BF39_1569	COG1664	Polymer-forming cytoskeletal
BF39_1570	COG0789	Transcriptional regulator
BF39_1571	COG4533	DNA binding
BF39_1572	COG0477	Major facilitator Superfamily
BF39_1572	COG2814	Major facilitator Superfamily
BF39_1576	COG2261	transglycosylase associated protein
BF39_1579	COG2226	methyltransferase
BF39_158	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_1586	COG0436	Aminotransferase
BF39_1587	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF39_1588	COG5146	pantothenate kinase activity
BF39_159	COG0028	Belongs to the TPP enzyme family
BF39_1592	COG1131	(ABC) transporter
BF39_16	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_160	COG0440	acetolactate synthase activity
BF39_1601	COG0628	permease
BF39_1603	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_1604	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_1605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_1606	COG1116	anion transmembrane transporter activity
BF39_161	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF39_1614	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF39_1619	COG0697	spore germination
BF39_1620	COG2318	DinB family
BF39_1624	COG4912	Dna alkylation repair
BF39_1626	COG0726	polysaccharide deacetylase
BF39_1628	COG0861	Integral membrane protein TerC family
BF39_1629	COG1368	sulfuric ester hydrolase activity
BF39_163	COG0473	3-isopropylmalate dehydrogenase activity
BF39_1630	COG0488	(ABC) transporter
BF39_1632	COG2409	Drug exporters of the RND superfamily
BF39_1632	COG1033	growth of symbiont in host cell
BF39_1633	COG1033	growth of symbiont in host cell
BF39_1633	COG2409	Drug exporters of the RND superfamily
BF39_1634	COG1309	transcriptional regulator
BF39_1637	COG0287	Prephenate dehydrogenase
BF39_1638	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF39_1639	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF39_1640	COG1605	Chorismate mutase
BF39_1640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF39_1648	COG3584	3D domain protein
BF39_1648	COG1388	LysM domain
BF39_1650	COG1595	DNA-templated transcription, initiation
BF39_1656	COG1879	ABC-type sugar transport system periplasmic component
BF39_1658	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF39_1660	COG2390	Transcriptional regulator
BF39_1661	COG1070	Carbohydrate kinase
BF39_1668	COG2329	Antibiotic biosynthesis monooxygenase
BF39_1672	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_1674	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF39_1675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_1676	COG4187	Peptidase family M20/M25/M40
BF39_1677	COG1414	Transcriptional regulator
BF39_1678	COG0833	amino acid
BF39_1679	COG1690	Belongs to the RtcB family
BF39_168	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF39_1680	COG3239	Fatty acid desaturase
BF39_1681	COG1785	Belongs to the alkaline phosphatase family
BF39_1683	COG3655	Transcriptional regulator
BF39_1686	COG4377	Putative membrane peptidase family (DUF2324)
BF39_1688	COG3279	Response regulator of the LytR AlgR family
BF39_1690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_1691	COG0346	lactoylglutathione lyase activity
BF39_1695	COG0714	Associated with various cellular activities
BF39_1700	COG0463	Glycosyl transferase, family 2
BF39_1705	COG0463	Glycosyl transferase, family 2
BF39_1707	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF39_1708	COG0753	catalase activity
BF39_1710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF39_1716	COG0714	Associated with various cellular activities
BF39_1718	COG0778	Nitroreductase
BF39_1719	COG1846	Transcriptional regulator
BF39_1726	COG1725	Transcriptional regulator
BF39_1728	COG0577	efflux transmembrane transporter activity
BF39_1728	COG1136	(ABC) transporter
BF39_1733	COG2207	Transcriptional regulator
BF39_1734	COG0456	acetyltransferase
BF39_1738	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_1743	COG0642	Histidine kinase
BF39_1744	COG0745	RESPONSE REGULATOR receiver
BF39_1745	COG0596	Alpha beta hydrolase
BF39_175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF39_1751	COG0730	response to heat
BF39_1753	COG0833	amino acid
BF39_1755	COG4335	DNA alkylation repair
BF39_1765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF39_1771	COG1984	allophanate hydrolase subunit 2
BF39_1772	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF39_1773	COG1414	Transcriptional regulator
BF39_1776	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_1777	COG0640	Transcriptional regulator
BF39_1779	COG1960	acyl-CoA dehydrogenase activity
BF39_178	COG1183	phosphatidylcholine synthase activity
BF39_1786	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF39_1789	COG0574	Belongs to the PEP-utilizing enzyme family
BF39_1789	COG3848	Pyruvate phosphate dikinase
BF39_179	COG1368	sulfuric ester hydrolase activity
BF39_1790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_1793	COG5577	PFAM Coat F domain
BF39_1795	COG3403	YqcI/YcgG family
BF39_1796	COG1280	lysine exporter protein (LysE YggA)
BF39_1797	COG1113	amino acid transport
BF39_1798	COG1113	amino acid transport
BF39_18	COG1476	TRANSCRIPTIONal
BF39_1804	COG1063	alcohol dehydrogenase
BF39_1807	COG1027	Aspartate ammonia-lyase
BF39_1808	COG0252	asparaginase activity
BF39_1809	COG1396	sequence-specific DNA binding
BF39_181	COG0019	diaminopimelate decarboxylase activity
BF39_1811	COG0322	excinuclease ABC activity
BF39_1812	COG0531	amino acid
BF39_1813	COG1114	Component of the transport system for branched-chain amino acids
BF39_1814	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_1816	COG0281	malic enzyme
BF39_1820	COG0531	amino acid
BF39_1821	COG0697	spore germination
BF39_1822	COG0784	Response regulator, receiver
BF39_1823	COG4191	Histidine kinase
BF39_1824	COG4191	Histidine kinase
BF39_1825	COG2066	Belongs to the glutaminase family
BF39_1827	COG1115	amino acid carrier protein
BF39_1833	COG0737	Belongs to the 5'-nucleotidase family
BF39_1834	COG0753	catalase activity
BF39_1835	COG2267	carboxylic ester hydrolase activity
BF39_1836	COG1335	isochorismatase
BF39_1841	COG0583	DNA-binding transcription factor activity
BF39_1842	COG1846	Transcriptional regulator
BF39_1843	COG0598	Magnesium transport protein CorA
BF39_1844	COG0598	Magnesium transport protein CorA
BF39_185	COG0529	Catalyzes the synthesis of activated sulfate
BF39_1851	COG0415	Belongs to the DNA photolyase family
BF39_1852	COG0288	reversible hydration of carbon dioxide
BF39_1854	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF39_1855	COG5609	conserved protein (DUF2294)
BF39_1857	COG1575	Belongs to the MenA family. Type 1 subfamily
BF39_1858	COG2267	carboxylic ester hydrolase activity
BF39_1859	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF39_186	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF39_1860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF39_1861	COG1121	(ABC) transporter
BF39_1867	COG0798	PFAM Bile acid sodium symporter
BF39_1868	COG0346	lactoylglutathione lyase activity
BF39_1869	COG0640	Transcriptional regulator
BF39_1873	COG0443	Heat shock 70 kDa protein
BF39_1876	COG1522	sequence-specific DNA binding
BF39_1879	COG0346	lactoylglutathione lyase activity
BF39_1891	COG2814	Major facilitator Superfamily
BF39_1896	COG0745	RESPONSE REGULATOR receiver
BF39_1897	COG5002	protein histidine kinase activity
BF39_1897	COG3850	Histidine kinase
BF39_190	COG1648	precorrin-2 dehydrogenase activity
BF39_1902	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF39_1908	COG1476	TRANSCRIPTIONal
BF39_191	COG0733	neurotransmitter:sodium symporter activity
BF39_1911	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_1912	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_1914	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_1915	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF39_1918	COG1136	(ABC) transporter
BF39_1919	COG0577	efflux transmembrane transporter activity
BF39_1922	COG5002	protein histidine kinase activity
BF39_1922	COG3850	Histidine kinase
BF39_1924	COG2364	Membrane
BF39_1925	COG1846	Transcriptional regulator
BF39_1926	COG0456	acetyltransferase
BF39_1927	COG2808	Putative FMN-binding domain
BF39_1928	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_1929	COG2271	Major facilitator Superfamily
BF39_1930	COG1556	Lactate utilization protein
BF39_1931	COG1139	Iron-sulfur cluster binding protein
BF39_1933	COG0583	DNA-binding transcription factor activity
BF39_1935	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_1939	COG0738	Major facilitator superfamily
BF39_1940	COG0673	inositol 2-dehydrogenase activity
BF39_1941	COG0561	phosphatase activity
BF39_1942	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF39_1943	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF39_1944	COG1609	Transcriptional regulator
BF39_1945	COG0457	Tetratricopeptide repeat
BF39_1949	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF39_195	COG1757	Na H antiporter
BF39_1952	COG0840	transmembrane signaling receptor activity
BF39_1957	COG0534	Mate efflux family protein
BF39_1960	COG2184	nucleotidyltransferase activity
BF39_1961	COG2814	Major facilitator Superfamily
BF39_1962	COG1309	transcriptional regulator
BF39_1965	COG0814	amino acid
BF39_1966	COG1760	l-serine dehydratase
BF39_1967	COG1760	l-serine dehydratase
BF39_1968	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF39_1969	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF39_1971	COG1335	isochorismatase
BF39_1972	COG1522	sequence-specific DNA binding
BF39_1973	COG0531	amino acid
BF39_1976	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF39_198	COG4758	membrane
BF39_1980	COG1595	DNA-templated transcription, initiation
BF39_1983	COG0662	Cupin 2, conserved barrel domain protein
BF39_1984	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_1984	COG2207	Transcriptional regulator
BF39_199	COG4585	Histidine kinase
BF39_1995	COG0477	Major facilitator Superfamily
BF39_1997	COG1846	Transcriptional regulator
BF39_1998	COG2814	Major facilitator Superfamily
BF39_200	COG2197	response regulator
BF39_2001	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_2002	COG1131	(ABC) transporter
BF39_2006	COG2076	Multidrug Resistance protein
BF39_2007	COG1309	transcriptional regulator
BF39_2009	COG2031	fatty acid transporter
BF39_2011	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_2017	COG1122	ATPase activity
BF39_2018	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF39_202	COG1114	Component of the transport system for branched-chain amino acids
BF39_2021	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF39_2022	COG1288	antiporter activity
BF39_2023	COG2356	endonuclease I
BF39_2026	COG3620	sequence-specific DNA binding
BF39_2027	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_2028	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF39_2029	COG0124	histidyl-tRNA synthetase
BF39_2032	COG1733	regulation of RNA biosynthetic process
BF39_2033	COG0778	Nitroreductase
BF39_2037	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2039	COG1131	(ABC) transporter
BF39_204	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF39_2044	COG1011	Hydrolase
BF39_2051	COG0346	lactoylglutathione lyase activity
BF39_2052	COG1940	carbohydrate kinase activity
BF39_2053	COG0738	Major facilitator superfamily
BF39_2054	COG0110	maltose O-acetyltransferase activity
BF39_2056	COG1136	(ABC) transporter
BF39_2058	COG0180	Tryptophanyl-tRNA synthetase
BF39_2059	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF39_2060	COG0628	permease
BF39_2064	COG2226	methyltransferase
BF39_2066	COG0477	Major facilitator Superfamily
BF39_2072	COG1253	flavin adenine dinucleotide binding
BF39_2073	COG0789	Transcriptional regulator
BF39_2074	COG0697	spore germination
BF39_2075	COG1357	PFAM Pentapeptide repeats (8 copies)
BF39_2076	COG3813	Protein conserved in bacteria
BF39_2077	COG2706	6-phosphogluconolactonase activity
BF39_2078	COG1070	Carbohydrate kinase
BF39_2080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF39_2081	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF39_2083	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF39_2084	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF39_2085	COG0604	alcohol dehydrogenase
BF39_2086	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_2089	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_209	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF39_209	COG1017	nitric oxide dioxygenase activity
BF39_2094	COG0656	L-ascorbic acid biosynthetic process
BF39_2095	COG2814	Major facilitator Superfamily
BF39_2098	COG0346	lactoylglutathione lyase activity
BF39_2099	COG0814	amino acid
BF39_2104	COG1393	Belongs to the ArsC family
BF39_2105	COG1733	regulation of RNA biosynthetic process
BF39_2106	COG2188	Transcriptional regulator
BF39_2107	COG0673	inositol 2-dehydrogenase activity
BF39_2109	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF39_2110	COG1733	regulation of RNA biosynthetic process
BF39_2111	COG1733	regulation of RNA biosynthetic process
BF39_2114	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_2118	COG0384	phenazine biosynthesis protein PhzF
BF39_212	COG0730	response to heat
BF39_2120	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2122	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_2124	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_2125	COG1733	regulation of RNA biosynthetic process
BF39_2129	COG0726	polysaccharide deacetylase
BF39_213	COG0306	phosphate transporter
BF39_2132	COG1191	sigma factor activity
BF39_2135	COG1309	transcriptional regulator
BF39_2139	COG3152	Membrane
BF39_214	COG1392	Phosphate transport regulator
BF39_2144	COG1151	hydroxylamine reductase activity
BF39_2147	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_2148	COG3409	Peptidoglycan-binding domain 1 protein
BF39_2148	COG3757	hydrolase, family 25
BF39_215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_2155	COG2072	flavoprotein involved in K transport
BF39_2162	COG0604	alcohol dehydrogenase
BF39_2163	COG1113	amino acid transport
BF39_2164	COG2814	Major facilitator Superfamily
BF39_217	COG3852	Histidine kinase
BF39_2170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_2171	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_2175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_2177	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_2178	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_2179	COG3739	integral membrane protein
BF39_218	COG1801	Protein of unknown function DUF72
BF39_2180	COG0384	phenazine biosynthesis protein PhzF
BF39_2186	COG0583	DNA-binding transcription factor activity
BF39_2190	COG1193	negative regulation of DNA recombination
BF39_2193	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF39_2194	COG1164	Oligoendopeptidase f
BF39_2195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_220	COG0582	viral genome integration into host DNA
BF39_2201	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_2205	COG0640	Transcriptional regulator
BF39_2206	COG0604	alcohol dehydrogenase
BF39_2208	COG0457	Tetratricopeptide repeat
BF39_221	COG5002	protein histidine kinase activity
BF39_2211	COG2808	Putative FMN-binding domain
BF39_2212	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_2214	COG0385	Bile acid
BF39_2215	COG0277	FAD linked oxidase domain protein
BF39_2221	COG1216	Glycosyl transferase, family 2
BF39_2222	COG1024	Enoyl-CoA hydratase
BF39_2224	COG1285	pathogenesis
BF39_2226	COG2514	catechol 2,3-dioxygenase activity
BF39_2227	COG2720	vancomycin resistance protein
BF39_2233	COG1278	Cold shock
BF39_2235	COG0716	FMN binding
BF39_2241	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2243	COG0165	Argininosuccinate lyase
BF39_2246	COG4145	pantothenate transmembrane transporter activity
BF39_2248	COG1012	belongs to the aldehyde dehydrogenase family
BF39_2249	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_225	COG0392	lysyltransferase activity
BF39_225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF39_2251	COG1657	PFAM Prenyltransferase squalene oxidase
BF39_2252	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF39_2253	COG2962	Rard protein
BF39_2254	COG3326	Membrane
BF39_2257	COG0489	protein tyrosine kinase activity
BF39_2259	COG0314	molybdopterin synthase activity
BF39_2260	COG0303	'Molybdopterin
BF39_2261	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_2262	COG2116	formate transmembrane transporter activity
BF39_2264	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF39_2265	COG5609	conserved protein (DUF2294)
BF39_2266	COG2427	Protein of unknown function (DUF1641)
BF39_2267	COG3383	formate dehydrogenase (NAD+) activity
BF39_2269	COG0697	spore germination
BF39_2277	COG2226	methyltransferase
BF39_2278	COG4166	transmembrane transport
BF39_2279	COG4166	transmembrane transport
BF39_228	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_2280	COG4166	transmembrane transport
BF39_2281	COG1301	dicarboxylic acid transport
BF39_2282	COG1316	TRANSCRIPTIONal
BF39_2284	COG1595	DNA-templated transcription, initiation
BF39_2288	COG1131	(ABC) transporter
BF39_229	COG1686	Belongs to the peptidase S11 family
BF39_2290	COG0673	inositol 2-dehydrogenase activity
BF39_2291	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF39_2292	COG0187	DNA topoisomerase II activity
BF39_2293	COG1832	CoA-binding protein
BF39_2294	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_2295	COG0745	RESPONSE REGULATOR receiver
BF39_2298	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_2299	COG4841	protein insertion into membrane
BF39_230	COG2715	membrane protein required for spore maturation
BF39_2300	COG0824	Thioesterase
BF39_2306	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_2308	COG2274	protein secretion by the type I secretion system
BF39_2309	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF39_231	COG0700	Nucleoside recognition
BF39_2311	COG0726	polysaccharide deacetylase
BF39_2315	COG2211	Major facilitator Superfamily
BF39_2317	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_232	COG1187	pseudouridine synthase activity
BF39_2320	COG0183	Belongs to the thiolase family
BF39_2321	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_2322	COG1268	BioY protein
BF39_2323	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_2332	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_2334	COG5002	protein histidine kinase activity
BF39_2335	COG0400	carboxylic ester hydrolase activity
BF39_2336	COG0346	lactoylglutathione lyase activity
BF39_2337	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_2338	COG0069	glutamate synthase activity
BF39_2339	COG1902	pentaerythritol trinitrate reductase activity
BF39_234	COG1333	cytochrome c biogenesis protein
BF39_2340	COG1329	Transcriptional regulator
BF39_2341	COG0010	Belongs to the arginase family
BF39_2346	COG2226	methyltransferase
BF39_235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF39_2356	COG4846	Membrane protein involved in cytochrome C biogenesis
BF39_2357	COG0785	Cytochrome C biogenesis protein
BF39_2359	COG0583	DNA-binding transcription factor activity
BF39_236	COG0745	RESPONSE REGULATOR receiver
BF39_2360	COG1380	Effector of murein hydrolase LrgA
BF39_2361	COG1346	cytolysis
BF39_2364	COG0730	response to heat
BF39_2366	COG3409	Peptidoglycan-binding domain 1 protein
BF39_2366	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_2369	COG1132	(ABC) transporter
BF39_237	COG5002	protein histidine kinase activity
BF39_2370	COG1132	(ABC) transporter
BF39_2376	COG3639	organic phosphonate transmembrane transporter activity
BF39_2377	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF39_238	COG2096	Adenosyltransferase
BF39_2380	COG0737	Belongs to the 5'-nucleotidase family
BF39_2382	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF39_2386	COG1695	Transcriptional regulator
BF39_2394	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_2394	COG1388	LysM domain
BF39_2394	COG3409	Peptidoglycan-binding domain 1 protein
BF39_2395	COG4824	toxin secretion phage lysis holin
BF39_241	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF39_242	COG1141	Ferredoxin
BF39_2427	COG1595	DNA-templated transcription, initiation
BF39_243	COG4955	Helix-turn-helix domain
BF39_2435	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF39_244	COG0514	ATP-dependent DNA helicase (RecQ)
BF39_245	COG1266	CAAX protease self-immunity
BF39_2451	COG1396	sequence-specific DNA binding
BF39_2456	COG0174	glutamine synthetase
BF39_2457	COG0789	Transcriptional regulator
BF39_2458	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF39_2459	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF39_2460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF39_2461	COG2860	membrane
BF39_2462	COG0464	growth
BF39_2469	COG1388	LysM domain
BF39_2469	COG3584	3D domain protein
BF39_247	COG1408	metallophosphoesterase
BF39_2470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF39_2470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF39_2470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_2471	COG1105	Belongs to the carbohydrate kinase PfkB family
BF39_2472	COG1349	DNA-binding transcription factor activity
BF39_2473	COG1979	alcohol dehydrogenase
BF39_2474	COG1979	alcohol dehydrogenase
BF39_2475	COG2322	membrane
BF39_2478	COG1113	amino acid transport
BF39_2481	COG1408	metallophosphoesterase
BF39_2482	COG2116	formate transmembrane transporter activity
BF39_2484	COG2217	Heavy metal translocating P-type atpase
BF39_2485	COG2608	mercury ion transmembrane transporter activity
BF39_2486	COG1937	Protein conserved in bacteria
BF39_2488	COG2819	hydrolase of the alpha beta superfamily
BF39_2489	COG1120	ATPase activity
BF39_249	COG4862	establishment of competence for transformation
BF39_2490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_2491	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_2492	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_2494	COG0708	Exodeoxyribonuclease III
BF39_2495	COG2169	Transcriptional regulator
BF39_2496	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF39_2497	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF39_2499	COG2364	Membrane
BF39_250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF39_2502	COG2267	carboxylic ester hydrolase activity
BF39_2503	COG0346	lactoylglutathione lyase activity
BF39_2504	COG3300	MHYT domain
BF39_2504	COG5001	Diguanylate cyclase
BF39_2507	COG1346	cytolysis
BF39_2508	COG1380	Effector of murein hydrolase LrgA
BF39_2509	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_2510	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_2510	COG0596	Alpha beta hydrolase
BF39_2511	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_2514	COG1404	Belongs to the peptidase S8 family
BF39_2515	COG3773	Cell wall hydrolase
BF39_2516	COG0562	UDP-galactopyranose mutase
BF39_2517	COG1368	sulfuric ester hydrolase activity
BF39_2518	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_2520	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF39_2529	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF39_2530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF39_2531	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF39_2532	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF39_2532	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF39_2534	COG2359	stage V sporulation protein S
BF39_2535	COG1692	metallophosphoesterase
BF39_254	COG0492	ferredoxin-NADP+ reductase activity
BF39_2540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF39_2541	COG1426	Protein conserved in bacteria
BF39_2544	COG0300	oxidoreductase activity
BF39_2545	COG0612	Peptidase, M16
BF39_2546	COG0612	Peptidase, M16
BF39_255	COG0252	asparaginase activity
BF39_2552	COG2188	Transcriptional regulator
BF39_2553	COG1674	ftsk spoiiie
BF39_2555	COG0740	serine-type endopeptidase activity
BF39_2556	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_2558	COG0527	aspartate kinase activity
BF39_2559	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF39_2560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF39_2561	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF39_2562	COG1873	PFAM PRC-barrel domain
BF39_2563	COG0612	Peptidase, M16
BF39_2564	COG0726	polysaccharide deacetylase
BF39_2567	COG0196	riboflavin kinase activity
BF39_2568	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF39_2570	COG1550	Protein conserved in bacteria
BF39_2572	COG1358	cellular component organization or biogenesis
BF39_2573	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF39_2574	COG0195	Participates in both transcription termination and antitermination
BF39_2578	COG0750	zinc metalloprotease
BF39_2579	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF39_2580	COG4589	Belongs to the CDS family
BF39_2581	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF39_2583	COG0528	UMP kinase activity
BF39_2589	COG4974	Belongs to the 'phage' integrase family
BF39_2591	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF39_2593	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF39_2601	COG1837	Belongs to the UPF0109 family
BF39_2603	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF39_2605	COG0552	protein localization to endoplasmic reticulum
BF39_2606	COG1196	nuclear chromosome segregation
BF39_2609	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF39_2613	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF39_2614	COG1461	Dihydroxyacetone kinase
BF39_2615	COG1302	Protein conserved in bacteria
BF39_2617	COG1564	THIamine pyrophosphokinase
BF39_2618	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF39_2619	COG1162	GTPase activity
BF39_2620	COG2815	serine threonine protein kinase
BF39_2620	COG0515	serine threonine protein kinase
BF39_2621	COG0631	protein serine/threonine phosphatase activity
BF39_2623	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF39_2623	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF39_2625	COG0242	peptide deformylase activity
BF39_2626	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF39_2627	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF39_2629	COG0194	GDP metabolic process
BF39_2631	COG1561	YicC-like family, N-terminal region
BF39_2632	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF39_2634	COG0006	proline dipeptidase activity
BF39_2637	COG3069	C4-dicarboxylate transmembrane transporter activity
BF39_2645	COG0505	Belongs to the CarA family
BF39_2650	COG0564	pseudouridine synthase activity
BF39_2653	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF39_2654	COG3599	regulation of cell shape
BF39_2655	COG2302	S4 RNA-binding domain
BF39_2656	COG0762	integral membrane protein
BF39_2658	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF39_2660	COG1873	PFAM PRC-barrel domain
BF39_2661	COG1191	sigma factor activity
BF39_2662	COG1191	sigma factor activity
BF39_2664	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF39_2665	COG0849	cell division
BF39_2666	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF39_2667	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF39_2668	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF39_2669	COG0772	Belongs to the SEDS family
BF39_2672	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_2673	COG0768	penicillin binding
BF39_2675	COG4839	cell division protein FtsL
BF39_2678	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF39_2682	COG1399	metal-binding, possibly nucleic acid-binding protein
BF39_269	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_2692	COG4824	toxin secretion phage lysis holin
BF39_2711	COG4626	Terminase
BF39_2711	COG1802	Transcriptional regulator
BF39_2716	COG0582	viral genome integration into host DNA
BF39_272	COG0142	geranyltranstransferase activity
BF39_2731	COG1191	sigma factor activity
BF39_2736	COG1484	DNA-dependent DNA replication
BF39_274	COG0142	geranyltranstransferase activity
BF39_2742	COG1396	sequence-specific DNA binding
BF39_2746	COG1396	sequence-specific DNA binding
BF39_275	COG0105	UTP biosynthetic process
BF39_2750	COG0582	viral genome integration into host DNA
BF39_2752	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF39_2753	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF39_2755	COG3314	Sporulation integral membrane protein YlbJ
BF39_2756	COG0742	ribosomal rna small subunit methyltransferase
BF39_2760	COG3679	Belongs to the UPF0342 family
BF39_2761	COG0406	alpha-ribazole phosphatase activity
BF39_2764	COG2340	Cysteine-rich secretory protein family
BF39_2767	COG3336	cytochrome c oxidase
BF39_2774	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF39_2775	COG0772	Belongs to the SEDS family
BF39_2776	COG4838	Belongs to the UPF0358 family
BF39_2777	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF39_2778	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF39_278	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF39_2780	COG4896	Protein conserved in bacteria
BF39_2785	COG0483	inositol monophosphate 1-phosphatase activity
BF39_2789	COG1982	Orn Lys Arg decarboxylase major
BF39_279	COG0457	Tetratricopeptide repeat
BF39_2798	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_2799	COG0022	dehydrogenase e1 component
BF39_2800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_2802	COG0242	peptide deformylase activity
BF39_2803	COG0561	phosphatase activity
BF39_2805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_2806	COG0569	domain protein
BF39_2810	COG0583	DNA-binding transcription factor activity
BF39_2811	COG0517	IMP dehydrogenase activity
BF39_2813	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF39_2815	COG4703	Protein of unknown function (DUF1797)
BF39_2818	COG2200	EAL domain
BF39_2819	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2820	COG1408	metallophosphoesterase
BF39_2822	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF39_2829	COG2814	Major facilitator Superfamily
BF39_283	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF39_2833	COG3209	COG3209 Rhs family protein
BF39_2835	COG2205	protein histidine kinase activity
BF39_2837	COG0436	Aminotransferase
BF39_2838	COG1609	Transcriptional regulator
BF39_2839	COG3833	ABC-type maltose transport systems, permease component
BF39_2840	COG1175	transmembrane transport
BF39_2841	COG2182	Extracellular solute-binding protein
BF39_2843	COG0366	Alpha amylase catalytic
BF39_2844	COG3842	ATPase activity
BF39_285	COG4347	Protein of unknown function (DUF1405)
BF39_2852	COG0183	Belongs to the thiolase family
BF39_2859	COG1695	Transcriptional regulator
BF39_2860	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_2864	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF39_2865	COG0436	Aminotransferase
BF39_2869	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF39_2872	COG2084	Dehydrogenase
BF39_2873	COG2084	Dehydrogenase
BF39_2874	COG3706	GGDEF domain
BF39_2875	COG0778	Nitroreductase
BF39_288	COG2738	Putative neutral zinc metallopeptidase
BF39_2880	COG1263	PTS System
BF39_2880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_2880	COG2190	(PTS) system
BF39_2881	COG3711	transcriptional antiterminator
BF39_2890	COG1547	Domain of unknown function (DUF309)
BF39_2891	COG0456	acetyltransferase
BF39_2892	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF39_2893	COG4086	secreted protein
BF39_2894	COG0561	phosphatase activity
BF39_2895	COG0697	spore germination
BF39_2898	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_29	COG2226	methyltransferase
BF39_290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_2903	COG0733	neurotransmitter:sodium symporter activity
BF39_2907	COG1686	Belongs to the peptidase S11 family
BF39_2908	COG1725	Transcriptional regulator
BF39_2909	COG1131	(ABC) transporter
BF39_291	COG1694	Mazg nucleotide pyrophosphohydrolase
BF39_2912	COG1846	Transcriptional regulator
BF39_2915	COG0598	Magnesium transport protein CorA
BF39_2920	COG4974	Belongs to the 'phage' integrase family
BF39_2922	COG0735	belongs to the Fur family
BF39_2923	COG1300	Membrane
BF39_2927	COG0667	Aldo Keto reductase
BF39_2928	COG0656	L-ascorbic acid biosynthetic process
BF39_2929	COG0456	acetyltransferase
BF39_2929	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_2931	COG1525	nuclease
BF39_2931	COG0737	Belongs to the 5'-nucleotidase family
BF39_2931	COG4085	toxin activity
BF39_2933	COG0596	Alpha beta hydrolase
BF39_2934	COG2056	Na+-H+ antiporter family
BF39_2935	COG1609	Transcriptional regulator
BF39_2936	COG0456	acetyltransferase
BF39_2937	COG1073	alpha beta
BF39_294	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_2940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF39_2940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF39_2941	COG0307	riboflavin synthase, alpha
BF39_2945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF39_2946	COG4106	trans-aconitate 2-methyltransferase activity
BF39_2947	COG2226	methyltransferase
BF39_2947	COG1073	alpha beta
BF39_2948	COG0156	8-amino-7-oxononanoate synthase activity
BF39_295	COG0438	transferase activity, transferring glycosyl groups
BF39_2950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_2953	COG0737	Belongs to the 5'-nucleotidase family
BF39_2955	COG1522	sequence-specific DNA binding
BF39_2959	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF39_2961	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF39_2964	COG0300	oxidoreductase activity
BF39_2965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_2967	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_2968	COG1760	l-serine dehydratase
BF39_2969	COG1760	l-serine dehydratase
BF39_2972	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF39_2974	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF39_2975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_2977	COG1376	ErfK ybiS ycfS ynhG family protein
BF39_2978	COG4129	membrane
BF39_2979	COG1126	abc transporter atp-binding protein
BF39_2980	COG0765	amino acid transport
BF39_2981	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_2984	COG2816	NAD+ diphosphatase activity
BF39_2985	COG0772	Belongs to the SEDS family
BF39_2986	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_2987	COG0022	dehydrogenase e1 component
BF39_2988	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_2989	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF39_2991	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF39_2992	COG0280	phosphate acetyltransferase
BF39_2993	COG3290	protein histidine kinase activity
BF39_2993	COG3829	transcription factor binding
BF39_2995	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_2996	COG3093	addiction module antidote protein HigA
BF39_2998	COG0745	RESPONSE REGULATOR receiver
BF39_2999	COG0750	zinc metalloprotease
BF39_3000	COG0497	DNA recombination
BF39_3002	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF39_3004	COG0142	geranyltranstransferase activity
BF39_3009	COG1302	Protein conserved in bacteria
BF39_3010	COG0439	Biotin carboxylase
BF39_3011	COG0511	ligase activity, forming carbon-carbon bonds
BF39_302	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF39_302	COG1199	ATP-dependent helicase activity
BF39_3020	COG3854	ATPases associated with a variety of cellular activities
BF39_3025	COG0006	proline dipeptidase activity
BF39_3028	COG3872	metal-dependent enzyme
BF39_3029	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF39_3034	COG0095	Lipoate-protein ligase
BF39_3035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_3036	COG1609	Transcriptional regulator
BF39_3038	COG2076	Multidrug Resistance protein
BF39_3039	COG2076	Multidrug Resistance protein
BF39_3046	COG1131	(ABC) transporter
BF39_3047	COG1725	Transcriptional regulator
BF39_3053	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_306	COG3935	DnaD domain protein
BF39_3064	COG4970	Tfp pilus assembly protein FimT
BF39_3066	COG1459	type II secretion system
BF39_3067	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF39_307	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF39_3077	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF39_3078	COG1410	methionine synthase
BF39_3078	COG0646	methionine synthase
BF39_3079	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF39_3079	COG0646	methionine synthase
BF39_3080	COG0626	cystathionine gamma-synthase activity
BF39_3081	COG0626	cystathionine gamma-synthase activity
BF39_3085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_3087	COG1940	carbohydrate kinase activity
BF39_3088	COG4483	Protein conserved in bacteria
BF39_3089	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF39_309	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF39_309	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_3092	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF39_3093	COG0704	Plays a role in the regulation of phosphate uptake
BF39_3094	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF39_3095	COG0581	inorganic phosphate transmembrane transporter activity
BF39_3096	COG0573	inorganic phosphate transmembrane transporter activity
BF39_3097	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF39_3099	COG0477	Major facilitator Superfamily
BF39_31	COG1686	Belongs to the peptidase S11 family
BF39_3100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_3105	COG0735	belongs to the Fur family
BF39_3106	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF39_3107	COG1121	(ABC) transporter
BF39_3108	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_3114	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF39_3115	COG2384	SAM-dependent methyltransferase
BF39_3116	COG2010	Cytochrome c
BF39_3117	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF39_3118	COG0358	DNA primase activity
BF39_3120	COG0517	IMP dehydrogenase activity
BF39_3123	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF39_3124	COG0295	cytidine deaminase activity
BF39_3125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF39_3127	COG1480	7TM receptor with intracellular HD hydrolase
BF39_3128	COG1702	phosphate starvation-inducible protein PhoH
BF39_3131	COG1610	YqeY-like protein
BF39_3133	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF39_3134	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF39_3138	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF39_3140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF39_3141	COG1733	regulation of RNA biosynthetic process
BF39_3146	COG1466	dna polymerase III delta subunit
BF39_3148	COG2333	competence protein COMEC
BF39_3148	COG0658	competence protein
BF39_3149	COG2131	deaminase
BF39_3150	COG1596	polysaccharide export
BF39_3150	COG1555	photosystem II stabilization
BF39_3151	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_3152	COG2226	methyltransferase
BF39_3153	COG0799	negative regulation of ribosome biogenesis
BF39_3154	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF39_3156	COG1534	Rna-binding protein
BF39_3158	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF39_3159	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF39_3162	COG1191	sigma factor activity
BF39_3165	COG1595	DNA-templated transcription, initiation
BF39_3167	COG0778	Nitroreductase
BF39_3168	COG2357	RelA SpoT domain protein
BF39_3170	COG1785	Belongs to the alkaline phosphatase family
BF39_3172	COG2267	carboxylic ester hydrolase activity
BF39_3179	COG1404	Belongs to the peptidase S8 family
BF39_318	COG4474	Belongs to the UPF0398 family
BF39_3180	COG3186	Phenylalanine-4-hydroxylase
BF39_3182	COG2514	catechol 2,3-dioxygenase activity
BF39_3183	COG2514	catechol 2,3-dioxygenase activity
BF39_3184	COG2259	Doxx family
BF39_3192	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_3194	COG1454	alcohol dehydrogenase
BF39_3194	COG1012	belongs to the aldehyde dehydrogenase family
BF39_3195	COG0626	cystathionine gamma-synthase activity
BF39_3196	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_32	COG0681	Belongs to the peptidase S26 family
BF39_320	COG0116	Belongs to the methyltransferase superfamily
BF39_3201	COG0768	penicillin binding
BF39_3207	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF39_3211	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_3213	COG0628	permease
BF39_3217	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF39_3219	COG0482	sulfurtransferase activity
BF39_322	COG1199	ATP-dependent helicase activity
BF39_3220	COG1104	cysteine desulfurase activity
BF39_3221	COG1959	2 iron, 2 sulfur cluster binding
BF39_3222	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF39_3224	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF39_3226	COG0124	histidyl-tRNA synthetase
BF39_3229	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF39_323	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF39_3231	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF39_3231	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF39_3232	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF39_3233	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF39_3233	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF39_3235	COG2244	polysaccharide biosynthetic process
BF39_3236	COG2323	membrane
BF39_3238	COG1862	Preprotein translocase
BF39_3244	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF39_3246	COG0697	spore germination
BF39_3247	COG0697	spore germination
BF39_3248	COG0640	Transcriptional regulator
BF39_325	COG3173	Aminoglycoside phosphotransferase
BF39_3253	COG0157	Belongs to the NadC ModD family
BF39_3254	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF39_3255	COG1104	cysteine desulfurase activity
BF39_3256	COG1827	regulation of RNA biosynthetic process
BF39_3257	COG2258	MOSC domain
BF39_3258	COG0077	Prephenate dehydratase
BF39_3259	COG0577	efflux transmembrane transporter activity
BF39_326	COG0024	Methionine aminopeptidase
BF39_3260	COG0577	efflux transmembrane transporter activity
BF39_3261	COG1136	(ABC) transporter
BF39_3262	COG5002	protein histidine kinase activity
BF39_3264	COG0745	RESPONSE REGULATOR receiver
BF39_3265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF39_3266	COG3290	protein histidine kinase activity
BF39_3268	COG2868	ribosomal protein
BF39_3270	COG1530	ribonuclease E activity
BF39_3271	COG1994	Peptidase M50
BF39_3272	COG0739	heme binding
BF39_3273	COG2894	cell division
BF39_3276	COG1792	Involved in formation and maintenance of cell shape
BF39_3277	COG1077	Cell shape determining protein MreB Mrl
BF39_328	COG2233	PERMEase
BF39_3281	COG0285	dihydrofolate synthase activity
BF39_3282	COG0525	valine-tRNA ligase activity
BF39_3284	COG1388	LysM domain
BF39_3286	COG0113	porphobilinogen synthase activity
BF39_3287	COG1587	Uroporphyrinogen-III synthase
BF39_3289	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF39_329	COG2311	Membrane
BF39_3291	COG1846	Transcriptional regulator
BF39_3292	COG1764	response to oxidative stress
BF39_3295	COG1067	ATP-dependent peptidase activity
BF39_3295	COG0470	DNA polymerase III
BF39_3305	COG0622	Phosphoesterase
BF39_3306	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF39_3308	COG5401	PFAM Sporulation and spore germination
BF39_331	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_3312	COG1309	transcriptional regulator
BF39_3315	COG2197	response regulator
BF39_3316	COG2233	PERMEase
BF39_3318	COG0402	S-adenosylhomocysteine deaminase activity
BF39_3319	COG0402	S-adenosylhomocysteine deaminase activity
BF39_3323	COG0444	Belongs to the ABC transporter superfamily
BF39_3324	COG4608	Belongs to the ABC transporter superfamily
BF39_3325	COG3275	phosphorelay sensor kinase activity
BF39_3326	COG3279	Response regulator of the LytR AlgR family
BF39_3329	COG1983	PspC domain protein
BF39_333	COG0456	acetyltransferase
BF39_3330	COG1396	sequence-specific DNA binding
BF39_3331	COG0697	spore germination
BF39_3333	COG1959	2 iron, 2 sulfur cluster binding
BF39_3334	COG1668	transmembrane transport
BF39_3335	COG4152	abc transporter atp-binding protein
BF39_3336	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF39_3337	COG1360	Flagellar Motor Protein
BF39_3338	COG1360	Flagellar Motor Protein
BF39_3339	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF39_3340	COG1876	peptidase activity
BF39_3341	COG0824	Thioesterase
BF39_3342	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF39_3343	COG1053	succinate dehydrogenase
BF39_3344	COG2009	succinate dehydrogenase
BF39_3345	COG1719	4-vinyl reductase, 4VR
BF39_3347	COG3118	belongs to the thioredoxin family
BF39_3348	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF39_3349	COG2086	electron transfer activity
BF39_3350	COG1024	Enoyl-CoA hydratase
BF39_3351	COG1309	transcriptional regulator
BF39_3352	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_3356	COG2318	DinB family
BF39_3362	COG1131	(ABC) transporter
BF39_3363	COG2205	protein histidine kinase activity
BF39_3364	COG0745	RESPONSE REGULATOR receiver
BF39_3366	COG4895	conserved protein (DUF2196)
BF39_3367	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF39_3370	COG4509	Sortase family
BF39_3371	COG1120	ATPase activity
BF39_3374	COG5386	Cell surface protein
BF39_3376	COG5386	Cell surface protein
BF39_3377	COG1114	Component of the transport system for branched-chain amino acids
BF39_3378	COG1187	pseudouridine synthase activity
BF39_338	COG0754	glutathionylspermidine amidase activity
BF39_3381	COG1796	DNA polymerase
BF39_3381	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF39_3382	COG1286	toxin biosynthetic process
BF39_3388	COG0017	Asparaginyl-tRNA synthetase
BF39_3389	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_3389	COG0072	phenylalanine-tRNA ligase activity
BF39_3391	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF39_3393	COG1418	mRNA catabolic process
BF39_3398	COG2814	Major facilitator Superfamily
BF39_3399	COG1566	PFAM secretion protein HlyD family protein
BF39_3400	COG1309	transcriptional regulator
BF39_3401	COG1363	Peptidase, m42
BF39_3405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF39_3406	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_3408	COG1484	DNA-dependent DNA replication
BF39_3409	COG3611	Membrane attachment protein
BF39_341	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_3411	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF39_3412	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF39_3413	COG0237	dephospho-CoA kinase activity
BF39_3414	COG1971	Probably functions as a manganese efflux pump
BF39_3415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF39_3416	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_3416	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_3417	COG5002	protein histidine kinase activity
BF39_3418	COG0745	RESPONSE REGULATOR receiver
BF39_3422	COG0538	isocitrate dehydrogenase activity
BF39_3423	COG0372	Belongs to the citrate synthase family
BF39_3425	COG0628	permease
BF39_3426	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF39_3431	COG1725	Transcriptional regulator
BF39_3432	COG0281	malic enzyme
BF39_3433	COG0587	DNA-directed DNA polymerase activity
BF39_3436	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF39_3440	COG4109	DRTGG domain
BF39_3443	COG0006	proline dipeptidase activity
BF39_3450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_3451	COG0662	Cupin 2, conserved barrel domain protein
BF39_3453	COG1476	TRANSCRIPTIONal
BF39_3456	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_3457	COG0589	response to stress
BF39_3466	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_3470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF39_3471	COG0827	DNA restriction-modification system
BF39_3472	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF39_3473	COG3874	Sporulation protein YtfJ
BF39_3475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF39_3476	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF39_3478	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_348	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF39_3481	COG1104	cysteine desulfurase activity
BF39_3483	COG0583	DNA-binding transcription factor activity
BF39_3484	COG0697	spore germination
BF39_3485	COG1309	transcriptional regulator
BF39_3486	COG1309	transcriptional regulator
BF39_3487	COG1956	GAF domain-containing protein
BF39_3488	COG0626	cystathionine gamma-synthase activity
BF39_3492	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF39_3494	COG1595	DNA-templated transcription, initiation
BF39_3496	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_3497	COG0454	-acetyltransferase
BF39_3498	COG0517	IMP dehydrogenase activity
BF39_3499	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF39_3501	COG0745	RESPONSE REGULATOR receiver
BF39_3503	COG0666	response to abiotic stimulus
BF39_351	COG1215	transferase activity, transferring glycosyl groups
BF39_3510	COG1609	Transcriptional regulator
BF39_3511	COG4851	CamS sex pheromone cAM373 precursor
BF39_3512	COG3118	belongs to the thioredoxin family
BF39_3514	COG2309	aminopeptidase activity
BF39_3518	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_352	COG0438	transferase activity, transferring glycosyl groups
BF39_3521	COG1674	ftsk spoiiie
BF39_3524	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_3525	COG4848	Belongs to the UPF0354 family
BF39_3526	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_3527	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF39_3528	COG1363	Peptidase, m42
BF39_3530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_3533	COG0510	thiamine kinase activity
BF39_3534	COG1523	belongs to the glycosyl hydrolase 13 family
BF39_3536	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_3537	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_3538	COG1349	DNA-binding transcription factor activity
BF39_3539	COG1187	pseudouridine synthase activity
BF39_3540	COG2244	polysaccharide biosynthetic process
BF39_3541	COG2081	HI0933 family
BF39_3542	COG2814	Major facilitator Superfamily
BF39_3544	COG3832	glyoxalase III activity
BF39_3548	COG1329	Transcriptional regulator
BF39_355	COG0454	-acetyltransferase
BF39_3550	COG4975	Glucose uptake
BF39_3553	COG0314	molybdopterin synthase activity
BF39_3554	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF39_3555	COG0303	'Molybdopterin
BF39_3557	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_3558	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF39_3562	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_3564	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF39_3572	COG2814	Major facilitator Superfamily
BF39_3573	COG0475	glutathione-regulated potassium exporter activity
BF39_3574	COG0490	domain, Protein
BF39_3575	COG0582	viral genome integration into host DNA
BF39_3577	COG1136	(ABC) transporter
BF39_3581	COG1242	4 iron, 4 sulfur cluster binding
BF39_3582	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF39_3583	COG1131	(ABC) transporter
BF39_3585	COG1794	racemase activity, acting on amino acids and derivatives
BF39_3589	COG2267	carboxylic ester hydrolase activity
BF39_359	COG0328	RNA-DNA hybrid ribonuclease activity
BF39_3590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF39_3591	COG0671	phosphoesterase, PA-phosphatase related
BF39_3592	COG0438	transferase activity, transferring glycosyl groups
BF39_3594	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF39_3604	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF39_3605	COG5002	protein histidine kinase activity
BF39_3606	COG4191	Histidine kinase
BF39_3607	COG2267	carboxylic ester hydrolase activity
BF39_3608	COG1368	sulfuric ester hydrolase activity
BF39_3612	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_3613	COG1116	anion transmembrane transporter activity
BF39_3614	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_3618	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF39_3620	COG0494	nUDIX hydrolase
BF39_3625	COG0288	reversible hydration of carbon dioxide
BF39_3627	COG1271	oxidase subunit
BF39_3628	COG1294	oxidase, subunit
BF39_3632	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_3637	COG1842	Phage shock protein A
BF39_3644	COG5002	protein histidine kinase activity
BF39_3645	COG0745	RESPONSE REGULATOR receiver
BF39_3651	COG1597	lipid kinase activity
BF39_3658	COG0586	Pfam SNARE associated Golgi protein
BF39_3660	COG0577	efflux transmembrane transporter activity
BF39_3661	COG1136	(ABC) transporter
BF39_3662	COG2207	Transcriptional regulator
BF39_3662	COG3708	Transcriptional regulator
BF39_3663	COG0745	RESPONSE REGULATOR receiver
BF39_3664	COG2205	protein histidine kinase activity
BF39_3665	COG0577	efflux transmembrane transporter activity
BF39_3666	COG0577	efflux transmembrane transporter activity
BF39_3667	COG0577	efflux transmembrane transporter activity
BF39_3668	COG1136	(ABC) transporter
BF39_3669	COG0577	efflux transmembrane transporter activity
BF39_367	COG1280	lysine exporter protein (LysE YggA)
BF39_3670	COG0577	efflux transmembrane transporter activity
BF39_3677	COG3964	amidohydrolase
BF39_3683	COG4948	Mandelate Racemase Muconate Lactonizing
BF39_3685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF39_3686	COG0596	Alpha beta hydrolase
BF39_3687	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF39_3688	COG1169	isochorismate synthase
BF39_3689	COG1575	Belongs to the MenA family. Type 1 subfamily
BF39_3690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF39_3691	COG1278	Cold shock
BF39_3695	COG0058	SHG alpha-glucan phosphorylase activity
BF39_3696	COG0297	glycogen (starch) synthase activity
BF39_3697	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF39_3698	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF39_370	COG3162	membrane
BF39_3701	COG0039	L-malate dehydrogenase activity
BF39_371	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_372	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_3720	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF39_3728	COG1285	pathogenesis
BF39_3730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF39_3731	COG0166	Belongs to the GPI family
BF39_3732	COG2155	Conserved Protein
BF39_3733	COG1098	S1 RNA binding domain
BF39_3734	COG0436	Aminotransferase
BF39_3735	COG1522	sequence-specific DNA binding
BF39_3736	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF39_3737	COG2267	carboxylic ester hydrolase activity
BF39_3739	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF39_374	COG0475	glutathione-regulated potassium exporter activity
BF39_3743	COG5018	Exonuclease
BF39_3744	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_3747	COG0423	glycine-tRNA ligase activity
BF39_3748	COG2050	protein possibly involved in aromatic compounds catabolism
BF39_375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_3750	COG1268	BioY protein
BF39_3752	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF39_3753	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF39_3756	COG3584	3D domain protein
BF39_3759	COG1252	NADH dehydrogenase
BF39_376	COG4978	Transcriptional regulator
BF39_376	COG0789	Transcriptional regulator
BF39_3762	COG3708	Transcriptional regulator
BF39_3765	COG1683	Conserved Protein
BF39_3768	COG0316	Belongs to the HesB IscA family
BF39_3771	COG1252	NADH dehydrogenase
BF39_3773	COG0390	transport system, permease component
BF39_3774	COG2824	Alkylphosphonate utilization operon protein PhnA
BF39_378	COG2323	membrane
BF39_3782	COG4837	Protein of unknown function (DUF1462)
BF39_3783	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF39_3785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_3786	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF39_3788	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_3789	COG0647	UMP catabolic process
BF39_379	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF39_3791	COG2445	Protein of unknown function DUF86
BF39_3792	COG1494	fructose-1,6-bisphosphatase
BF39_3795	COG4470	Protein conserved in bacteria
BF39_3797	COG0789	Transcriptional regulator
BF39_3798	COG4377	Putative membrane peptidase family (DUF2324)
BF39_38	COG1012	belongs to the aldehyde dehydrogenase family
BF39_3803	COG0739	heme binding
BF39_3805	COG3377	Domain of unknown function (DUF1805)
BF39_3806	COG0737	Belongs to the 5'-nucleotidase family
BF39_3807	COG1695	Transcriptional regulator
BF39_3809	COG0719	Fe-S assembly protein
BF39_3810	COG0822	iron-sulfur transferase activity
BF39_3811	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF39_3812	COG0719	Fe-S assembly protein
BF39_3813	COG0396	ATPase activity
BF39_3814	COG1464	Belongs to the NlpA lipoprotein family
BF39_3815	COG1464	Belongs to the NlpA lipoprotein family
BF39_3816	COG2011	ABC-type metal ion transport system permease component
BF39_3817	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_3819	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_3820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF39_3822	COG1393	Belongs to the ArsC family
BF39_3831	COG0039	L-malate dehydrogenase activity
BF39_3836	COG1309	transcriptional regulator
BF39_3837	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_3838	COG1960	acyl-CoA dehydrogenase activity
BF39_3839	COG0183	Belongs to the thiolase family
BF39_3840	COG1024	Enoyl-CoA hydratase
BF39_3840	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF39_3842	COG1686	Belongs to the peptidase S11 family
BF39_3845	COG0011	TIGRFAM Protein of
BF39_3846	COG0840	transmembrane signaling receptor activity
BF39_3850	COG2814	Major facilitator Superfamily
BF39_3851	COG0531	amino acid
BF39_3853	COG0706	membrane insertase activity
BF39_3855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_3862	COG0586	Pfam SNARE associated Golgi protein
BF39_3864	COG1376	ErfK ybiS ycfS ynhG family protein
BF39_3865	COG0745	RESPONSE REGULATOR receiver
BF39_3866	COG5002	protein histidine kinase activity
BF39_3868	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_3871	COG2151	metal-sulfur cluster biosynthetic enzyme
BF39_3872	COG3227	Zinc metalloprotease (Elastase)
BF39_3873	COG1741	Belongs to the pirin family
BF39_3876	COG0475	glutathione-regulated potassium exporter activity
BF39_3877	COG0490	domain, Protein
BF39_3878	COG1115	amino acid carrier protein
BF39_3879	COG0783	Belongs to the Dps family
BF39_3882	COG1611	Belongs to the LOG family
BF39_3885	COG2311	Membrane
BF39_3887	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_3888	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_3889	COG1115	amino acid carrier protein
BF39_3890	COG1115	amino acid carrier protein
BF39_3891	COG2910	NAD(P)H-binding
BF39_3896	COG0656	L-ascorbic acid biosynthetic process
BF39_3897	COG2814	Major facilitator Superfamily
BF39_3898	COG1733	regulation of RNA biosynthetic process
BF39_39	COG3842	ATPase activity
BF39_390	COG1923	regulation of RNA biosynthetic process
BF39_3900	COG1252	NADH dehydrogenase
BF39_3901	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF39_3902	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF39_3904	COG3290	protein histidine kinase activity
BF39_3904	COG0840	transmembrane signaling receptor activity
BF39_3906	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF39_3907	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF39_3910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_3911	COG3223	Belongs to the PsiE family
BF39_392	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF39_3920	COG0557	exoribonuclease II activity
BF39_3921	COG1647	Serine aminopeptidase, S33
BF39_3922	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF39_3923	COG1346	cytolysis
BF39_393	COG1360	Flagellar Motor Protein
BF39_394	COG2201	protein-glutamate methylesterase activity
BF39_3942	COG4695	Portal protein
BF39_3947	COG4974	Belongs to the 'phage' integrase family
BF39_3949	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF39_395	COG0643	Histidine kinase
BF39_395	COG2198	Histidine kinase
BF39_3950	COG0149	triose-phosphate isomerase activity
BF39_3952	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF39_3955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF39_396	COG2198	Histidine kinase
BF39_396	COG0643	Histidine kinase
BF39_3960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_3963	COG2323	membrane
BF39_3964	COG0740	serine-type endopeptidase activity
BF39_3965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_3967	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF39_3969	COG1051	belongs to the nudix hydrolase family
BF39_397	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_397	COG1776	CheC inhibitor of MCP methylation
BF39_3971	COG0492	ferredoxin-NADP+ reductase activity
BF39_3972	COG0457	Tetratricopeptide repeat
BF39_3973	COG0110	maltose O-acetyltransferase activity
BF39_3977	COG1950	PFAM Membrane protein of
BF39_3979	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_3980	COG0556	nucleotide-excision repair
BF39_3984	COG0789	Transcriptional regulator
BF39_3988	COG2855	membrane
BF39_3989	COG0583	DNA-binding transcription factor activity
BF39_3991	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF39_3994	COG1132	(ABC) transporter
BF39_3995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_3996	COG3409	Peptidoglycan-binding domain 1 protein
BF39_3996	COG0793	Belongs to the peptidase S41A family
BF39_3997	COG2177	Part of the ABC transporter FtsEX involved in
BF39_3998	COG2884	Cell division ATP-binding protein ftsE
BF39_40	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF39_400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF39_4000	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF39_4001	COG0653	protein targeting
BF39_4002	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF39_4003	COG1278	Cold shock
BF39_4004	COG1040	competence protein
BF39_4005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF39_4006	COG0791	NLP P60 protein
BF39_4006	COG1388	LysM domain
BF39_4007	COG1733	regulation of RNA biosynthetic process
BF39_4008	COG1307	EDD domain protein, DegV family
BF39_4009	COG1739	Uncharacterized protein family UPF0029
BF39_4010	COG1316	TRANSCRIPTIONal
BF39_4011	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF39_4012	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF39_4013	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF39_4015	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF39_4015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF39_4018	COG3394	polysaccharide catabolic process
BF39_4019	COG1486	melibiose metabolic process
BF39_4020	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_4021	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_4023	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF39_4024	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF39_4025	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_4027	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_4028	COG1301	dicarboxylic acid transport
BF39_4030	COG0346	lactoylglutathione lyase activity
BF39_4031	COG1511	domain protein
BF39_4032	COG0583	DNA-binding transcription factor activity
BF39_4033	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF39_4036	COG1271	oxidase subunit
BF39_4037	COG1294	oxidase, subunit
BF39_4038	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_4040	COG1620	l-lactate permease
BF39_4042	COG2389	metal-binding protein
BF39_4044	COG1368	sulfuric ester hydrolase activity
BF39_4047	COG0791	NLP P60 protein
BF39_4047	COG1388	LysM domain
BF39_4048	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_4050	COG1215	transferase activity, transferring glycosyl groups
BF39_4052	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_4053	COG1388	LysM domain
BF39_4053	COG3584	3D domain protein
BF39_4058	COG4715	Zinc finger, swim domain protein
BF39_4059	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_406	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF39_4065	COG1191	sigma factor activity
BF39_4067	COG0577	efflux transmembrane transporter activity
BF39_4068	COG1136	(ABC) transporter
BF39_4075	COG5002	protein histidine kinase activity
BF39_4076	COG0745	RESPONSE REGULATOR receiver
BF39_4077	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF39_4080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF39_4081	COG1134	teichoic acid transport
BF39_4082	COG1682	transport, permease protein
BF39_4083	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF39_4091	COG1609	Transcriptional regulator
BF39_4093	COG0739	heme binding
BF39_4096	COG3279	Response regulator of the LytR AlgR family
BF39_4097	COG4555	ABC transporter
BF39_4098	COG2385	sporulation resulting in formation of a cellular spore
BF39_4099	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF39_41	COG1177	transmembrane transport
BF39_4101	COG4836	Membrane
BF39_4102	COG1007	ATP synthesis coupled electron transport
BF39_4103	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF39_4104	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF39_4106	COG0839	Belongs to the complex I subunit 6 family
BF39_4109	COG0649	NAD binding
BF39_411	COG1815	bacterial-type flagellum-dependent cell motility
BF39_4110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF39_4112	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF39_4113	COG5001	Diguanylate cyclase
BF39_4113	COG3300	MHYT domain
BF39_412	COG1558	bacterial-type flagellum-dependent cell motility
BF39_4123	COG0356	it plays a direct role in the translocation of protons across the membrane
BF39_4129	COG0698	ribose 5-phosphate isomerase
BF39_413	COG1677	Flagellar hook-basal body complex protein FliE
BF39_4131	COG2190	(PTS) system
BF39_4132	COG2259	Doxx family
BF39_4133	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF39_4136	COG0009	L-threonylcarbamoyladenylate synthase
BF39_4139	COG2890	protein-(glutamine-N5) methyltransferase activity
BF39_414	COG1766	The M ring may be actively involved in energy transduction
BF39_4140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF39_4143	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF39_4144	COG1494	fructose-1,6-bisphosphatase
BF39_4145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF39_4148	COG4821	SIS domain
BF39_4150	COG3343	RNA polymerase activity
BF39_4152	COG1960	acyl-CoA dehydrogenase activity
BF39_4153	COG1960	acyl-CoA dehydrogenase activity
BF39_4154	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF39_4155	COG0183	Belongs to the thiolase family
BF39_4156	COG2181	nitrate reductase activity
BF39_4156	COG0247	lactate metabolic process
BF39_4157	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_4159	COG5001	Diguanylate cyclase
BF39_4159	COG3300	MHYT domain
BF39_416	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_4163	COG2197	response regulator
BF39_4164	COG4585	Histidine kinase
BF39_4165	COG0842	Transport permease protein
BF39_4166	COG1131	(ABC) transporter
BF39_4167	COG0024	Methionine aminopeptidase
BF39_4171	COG2234	aminopeptidase activity
BF39_4175	COG1595	DNA-templated transcription, initiation
BF39_4176	COG0018	arginyl-trna synthetase
BF39_4177	COG4506	Protein conserved in bacteria
BF39_4178	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_418	COG1157	protein secretion by the type III secretion system
BF39_4181	COG0010	Belongs to the arginase family
BF39_4182	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF39_4183	COG2814	Major facilitator Superfamily
BF39_4184	COG0789	Transcriptional regulator
BF39_4185	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_4186	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_4188	COG1994	Peptidase M50
BF39_4190	COG1078	dGTPase activity
BF39_4191	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_4192	COG1120	ATPase activity
BF39_4193	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4194	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4199	COG0095	Lipoate-protein ligase
BF39_42	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF39_4200	COG0280	phosphate acetyltransferase
BF39_4203	COG3773	Cell wall hydrolase
BF39_4205	COG2363	Small membrane protein
BF39_4207	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF39_4208	COG2233	PERMEase
BF39_4209	COG0561	phosphatase activity
BF39_4210	COG2814	Major facilitator Superfamily
BF39_4212	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_4213	COG1131	(ABC) transporter
BF39_4214	COG2755	lipolytic protein G-D-S-L family
BF39_4215	COG1609	Transcriptional regulator
BF39_4217	COG0460	homoserine dehydrogenase
BF39_4221	COG1011	Hydrolase
BF39_4222	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF39_4224	COG2197	response regulator
BF39_4225	COG4585	Histidine kinase
BF39_4225	COG2203	Gaf domain
BF39_4226	COG4585	Histidine kinase
BF39_4226	COG2203	Gaf domain
BF39_4227	COG0351	phosphomethylpyrimidine kinase
BF39_4228	COG3706	GGDEF domain
BF39_4229	COG2879	small protein
BF39_4230	COG1966	Carbon starvation protein
BF39_4231	COG3279	Response regulator of the LytR AlgR family
BF39_4232	COG0477	Major facilitator Superfamily
BF39_4237	COG0840	transmembrane signaling receptor activity
BF39_4239	COG1607	acyl-coa hydrolase
BF39_4242	COG0488	(ABC) transporter
BF39_4247	COG0463	Glycosyl transferase, family 2
BF39_4248	COG1309	transcriptional regulator
BF39_4249	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF39_4250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_4250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_4251	COG0628	permease
BF39_4254	COG3279	Response regulator of the LytR AlgR family
BF39_4255	COG3275	phosphorelay sensor kinase activity
BF39_4256	COG2814	Major facilitator Superfamily
BF39_4257	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_4258	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF39_4259	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_4263	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF39_4264	COG1272	protein, Hemolysin III
BF39_4268	COG0516	GMP reductase activity
BF39_4269	COG1164	Oligoendopeptidase f
BF39_427	COG0835	chemotaxis
BF39_427	COG0784	Response regulator, receiver
BF39_4273	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_4274	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF39_4275	COG4853	Protein conserved in bacteria
BF39_4276	COG4863	YycH protein
BF39_4277	COG5002	protein histidine kinase activity
BF39_4278	COG0745	RESPONSE REGULATOR receiver
BF39_4284	COG0305	Participates in initiation and elongation during chromosome replication
BF39_4286	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF39_4287	COG4241	membrane
BF39_4289	COG0629	single-stranded DNA binding
BF39_429	COG0463	Glycosyl transferase, family 2
BF39_4291	COG0012	GTP binding
BF39_4292	COG4481	Protein conserved in bacteria
BF39_4293	COG0668	transmembrane transport
BF39_4295	COG1475	DNA binding
BF39_4296	COG1192	Involved in chromosome partitioning
BF39_4300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF39_4301	COG1847	R3H domain protein
BF39_4302	COG0706	membrane insertase activity
BF39_4306	COG0592	DNA-directed DNA polymerase activity
BF39_4307	COG2501	S4 domain
BF39_4309	COG0187	DNA topoisomerase II activity
BF39_4310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF39_4316	COG0516	GMP reductase activity
BF39_4316	COG0517	IMP dehydrogenase activity
BF39_4317	COG1686	Belongs to the peptidase S11 family
BF39_4323	COG1428	Deoxynucleoside kinase
BF39_4324	COG1428	Deoxynucleoside kinase
BF39_4325	COG1335	isochorismatase
BF39_4326	COG0590	tRNA wobble adenosine to inosine editing
BF39_4327	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF39_4337	COG1982	Orn Lys Arg decarboxylase major
BF39_4339	COG0470	DNA polymerase III
BF39_4340	COG1774	PSP1 C-terminal conserved region
BF39_4342	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF39_4344	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF39_4345	COG2002	toxin-antitoxin pair type II binding
BF39_4346	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_4346	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_4347	COG0084	hydrolase, TatD family'
BF39_4348	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF39_435	COG0463	Glycosyl transferase, family 2
BF39_435	COG0457	Tetratricopeptide repeat
BF39_4351	COG4466	Protein conserved in bacteria
BF39_4354	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF39_4355	COG0251	oxidation-reduction process
BF39_4358	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF39_4359	COG0193	aminoacyl-tRNA hydrolase activity
BF39_4361	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF39_4362	COG2002	toxin-antitoxin pair type II binding
BF39_4363	COG2244	polysaccharide biosynthetic process
BF39_4364	COG3956	TIGRFAM MazG family protein
BF39_4365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF39_4369	COG1098	S1 RNA binding domain
BF39_4372	COG2208	phosphoserine phosphatase activity
BF39_4373	COG0037	tRNA processing
BF39_4374	COG0037	tRNA processing
BF39_4376	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF39_4379	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_4380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF39_4381	COG0512	Glutamine amidotransferase of anthranilate synthase
BF39_4382	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_4383	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF39_4384	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF39_4385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF39_4386	COG1396	sequence-specific DNA binding
BF39_4387	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF39_4394	COG3880	PFAM UvrB UvrC protein
BF39_4396	COG0542	response to heat
BF39_4397	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF39_4399	COG4956	integral membrane protein (PIN domain superfamily)
BF39_44	COG2409	Drug exporters of the RND superfamily
BF39_440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF39_4403	COG1045	serine acetyltransferase
BF39_4406	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF39_4407	COG3688	RNA-binding protein containing a PIN domain
BF39_4409	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF39_441	COG0741	lytic transglycosylase activity
BF39_4410	COG0250	Participates in transcription elongation, termination and antitermination
BF39_4415	COG2813	Specifically methylates the guanine in position
BF39_4417	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF39_4418	COG1358	cellular component organization or biogenesis
BF39_442	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_4439	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF39_444	COG1776	CheC inhibitor of MCP methylation
BF39_444	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_4444	COG0201	protein transport
BF39_4446	COG0024	Methionine aminopeptidase
BF39_4448	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF39_4456	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF39_4457	COG0101	tRNA pseudouridine synthase activity
BF39_446	COG1338	Plays a role in the flagellum-specific transport system
BF39_4461	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_4462	COG0489	protein tyrosine kinase activity
BF39_4464	COG2194	sulfuric ester hydrolase activity
BF39_4465	COG0726	polysaccharide deacetylase
BF39_447	COG1987	bacterial-type flagellum assembly
BF39_4483	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF39_4484	COG4856	YbbR-like protein
BF39_4486	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF39_4487	COG0596	Alpha beta hydrolase
BF39_449	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF39_4492	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF39_4493	COG4946	Tricorn protease homolog
BF39_4493	COG1506	peptidase
BF39_4493	COG0823	Involved in the tonB-independent uptake of proteins
BF39_450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF39_4501	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_4502	COG2011	ABC-type metal ion transport system permease component
BF39_4503	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_4504	COG1464	Belongs to the NlpA lipoprotein family
BF39_4507	COG0277	FAD linked oxidase domain protein
BF39_4508	COG2271	Major facilitator Superfamily
BF39_451	COG1419	protein localization to endoplasmic reticulum
BF39_4510	COG2814	Major facilitator Superfamily
BF39_4513	COG0601	transmembrane transport
BF39_4514	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_4515	COG0444	Belongs to the ABC transporter superfamily
BF39_4516	COG4608	Belongs to the ABC transporter superfamily
BF39_4517	COG4166	transmembrane transport
BF39_4519	COG2207	Transcriptional regulator
BF39_452	COG4786	Flagellar basal body rod
BF39_4522	COG4166	transmembrane transport
BF39_4523	COG4166	transmembrane transport
BF39_4524	COG0656	L-ascorbic acid biosynthetic process
BF39_4525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_4528	COG4149	molybdate abc transporter
BF39_4529	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_453	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_4530	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_4531	COG1910	domain protein
BF39_4534	COG0583	DNA-binding transcription factor activity
BF39_4535	COG0697	spore germination
BF39_4538	COG0204	Acyl-transferase
BF39_4540	COG1609	Transcriptional regulator
BF39_4542	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_4545	COG0084	hydrolase, TatD family'
BF39_4546	COG5298	Protein conserved in bacteria
BF39_4550	COG0488	(ABC) transporter
BF39_4553	COG0747	negative chemotaxis
BF39_4554	COG0601	transmembrane transport
BF39_4556	COG0444	Belongs to the ABC transporter superfamily
BF39_4557	COG4608	Belongs to the ABC transporter superfamily
BF39_4558	COG0561	phosphatase activity
BF39_4559	COG0561	phosphatase activity
BF39_4565	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF39_4566	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF39_4568	COG2814	Major facilitator Superfamily
BF39_4571	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF39_4573	COG0457	Tetratricopeptide repeat
BF39_4573	COG0705	Rhomboid family
BF39_4574	COG4294	response to UV
BF39_4576	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF39_4577	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF39_4578	COG0864	Transcriptional regulator
BF39_4579	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF39_458	COG1309	transcriptional regulator
BF39_4580	COG2183	response to ionizing radiation
BF39_4599	COG0802	atpase or kinase
BF39_46	COG0564	pseudouridine synthase activity
BF39_4600	COG1214	PFAM Peptidase M22, glycoprotease
BF39_4601	COG0456	acetyltransferase
BF39_4602	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF39_4603	COG0488	(ABC) transporter
BF39_4606	COG1266	CAAX protease self-immunity
BF39_4610	COG2252	PERMEase
BF39_4612	COG5002	protein histidine kinase activity
BF39_462	COG2329	Antibiotic biosynthesis monooxygenase
BF39_4620	COG2226	methyltransferase
BF39_4626	COG1215	transferase activity, transferring glycosyl groups
BF39_4632	COG1968	undecaprenyl-diphosphatase activity
BF39_4635	COG2205	protein histidine kinase activity
BF39_4636	COG0745	RESPONSE REGULATOR receiver
BF39_4640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF39_4641	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF39_4642	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF39_4644	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF39_4647	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF39_4649	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF39_4651	COG0151	Belongs to the GarS family
BF39_4656	COG0210	DNA helicase
BF39_4658	COG4851	CamS sex pheromone cAM373 precursor
BF39_4662	COG1335	isochorismatase
BF39_4663	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_4664	COG2011	ABC-type metal ion transport system permease component
BF39_4665	COG1464	Belongs to the NlpA lipoprotein family
BF39_4668	COG0003	Pfam Anion-transporting ATPase
BF39_4669	COG0003	Pfam Anion-transporting ATPase
BF39_4670	COG1846	Transcriptional regulator
BF39_4671	COG4682	membrane
BF39_4675	COG1597	lipid kinase activity
BF39_4676	COG0546	phosphoglycolate phosphatase activity
BF39_4677	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF39_468	COG3842	ATPase activity
BF39_4680	COG1012	belongs to the aldehyde dehydrogenase family
BF39_4681	COG2076	Multidrug Resistance protein
BF39_4682	COG2309	aminopeptidase activity
BF39_4685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_4686	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF39_4687	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF39_4689	COG4807	Protein conserved in bacteria
BF39_469	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_4695	COG1473	amidohydrolase
BF39_4698	COG0450	alkyl hydroperoxide reductase
BF39_4699	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF39_470	COG1177	transmembrane transport
BF39_4701	COG0235	Class ii aldolase
BF39_4702	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4703	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4704	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_4707	COG0166	Belongs to the GPI family
BF39_471	COG1234	tRNA 3'-trailer cleavage
BF39_4713	COG5002	protein histidine kinase activity
BF39_4717	COG3541	Predicted nucleotidyltransferase
BF39_4718	COG2814	Major facilitator Superfamily
BF39_4719	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_4719	COG0723	plastoquinol--plastocyanin reductase activity
BF39_4721	COG0765	amino acid transport
BF39_4722	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_4724	COG0840	transmembrane signaling receptor activity
BF39_4725	COG0840	transmembrane signaling receptor activity
BF39_4726	COG0366	Alpha amylase catalytic
BF39_4727	COG2190	(PTS) system
BF39_4727	COG1263	PTS System
BF39_4727	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_4733	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF39_4736	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_4738	COG1116	anion transmembrane transporter activity
BF39_4739	COG0488	(ABC) transporter
BF39_4748	COG2270	Major facilitator Superfamily
BF39_4751	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_4754	COG2310	stress, protein
BF39_4755	COG2310	stress, protein
BF39_4756	COG2310	stress, protein
BF39_4757	COG0861	Integral membrane protein TerC family
BF39_4759	COG3853	Toxic anion resistance protein (TelA)
BF39_476	COG1686	Belongs to the peptidase S11 family
BF39_4762	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF39_4764	COG1295	ribonuclease BN
BF39_4765	COG2217	Heavy metal translocating P-type atpase
BF39_4766	COG0697	spore germination
BF39_4768	COG0681	Belongs to the peptidase S26 family
BF39_4771	COG0586	Pfam SNARE associated Golgi protein
BF39_4774	COG3871	stress protein (general stress protein 26)
BF39_4775	COG0387	Pfam Sodium calcium exchanger
BF39_4777	COG0535	radical SAM domain protein
BF39_478	COG0406	alpha-ribazole phosphatase activity
BF39_4782	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF39_4783	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF39_4784	COG0582	viral genome integration into host DNA
BF39_4788	COG1396	sequence-specific DNA binding
BF39_4795	COG1484	DNA-dependent DNA replication
BF39_48	COG2340	Cysteine-rich secretory protein family
BF39_4842	COG0101	tRNA pseudouridine synthase activity
BF39_4844	COG3829	transcription factor binding
BF39_4846	COG0833	amino acid
BF39_4847	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_485	COG0367	asparagine synthase
BF39_4852	COG2066	Belongs to the glutaminase family
BF39_4853	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_4853	COG1263	PTS System
BF39_4854	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_4857	COG0463	Glycosyl transferase, family 2
BF39_4860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_4860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF39_4863	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF39_4867	COG1228	amidohydrolase
BF39_4868	COG1090	epimerase
BF39_4874	COG1988	membrane-bound metal-dependent
BF39_4875	COG1194	a g-specific adenine glycosylase
BF39_4880	COG1132	(ABC) transporter
BF39_4881	COG4129	membrane
BF39_4882	COG0069	glutamate synthase activity
BF39_4882	COG0067	glutamate synthase
BF39_4882	COG0070	glutamate synthase
BF39_4884	COG4555	ABC transporter
BF39_4888	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF39_4889	COG0735	belongs to the Fur family
BF39_49	COG0247	lactate metabolic process
BF39_491	COG1802	Transcriptional regulator
BF39_4914	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF39_4915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF39_4917	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF39_4919	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF39_492	COG0697	spore germination
BF39_4922	COG2766	serine protein kinase
BF39_4926	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_4928	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF39_4929	COG2268	Band 7 protein
BF39_493	COG0523	cobalamin synthesis protein
BF39_4931	COG3290	protein histidine kinase activity
BF39_4932	COG4565	transcriptional regulatory protein
BF39_4933	COG2851	Citrate transporter
BF39_4937	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF39_4938	COG3842	ATPase activity
BF39_4939	COG1175	transmembrane transport
BF39_494	COG0701	Predicted permease
BF39_4940	COG0395	ABC-type sugar transport system, permease component
BF39_4942	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF39_4943	COG0745	RESPONSE REGULATOR receiver
BF39_4944	COG5002	protein histidine kinase activity
BF39_4946	COG4990	cell redox homeostasis
BF39_4948	COG3290	protein histidine kinase activity
BF39_4949	COG4565	transcriptional regulatory protein
BF39_4950	COG3493	citrate carrier protein
BF39_4951	COG0281	malic enzyme
BF39_4954	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_4956	COG5002	protein histidine kinase activity
BF39_4957	COG0745	RESPONSE REGULATOR receiver
BF39_4959	COG0454	-acetyltransferase
BF39_4959	COG0456	acetyltransferase
BF39_496	COG1216	Glycosyl transferase, family 2
BF39_496	COG0438	transferase activity, transferring glycosyl groups
BF39_4960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF39_4961	COG3383	formate dehydrogenase (NAD+) activity
BF39_4966	COG0531	amino acid
BF39_4967	COG0640	Transcriptional regulator
BF39_4968	COG2217	Heavy metal translocating P-type atpase
BF39_4969	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF39_497	COG1757	Na H antiporter
BF39_4972	COG3227	Zinc metalloprotease (Elastase)
BF39_4976	COG2720	vancomycin resistance protein
BF39_4977	COG1316	TRANSCRIPTIONal
BF39_4978	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_4979	COG0346	lactoylglutathione lyase activity
BF39_498	COG0114	fumarate hydratase activity
BF39_4980	COG1253	flavin adenine dinucleotide binding
BF39_4981	COG1027	Aspartate ammonia-lyase
BF39_4982	COG1620	l-lactate permease
BF39_4985	COG3104	oligopeptide transport
BF39_4986	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_4987	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4988	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_4990	COG2226	methyltransferase
BF39_4991	COG0156	8-amino-7-oxononanoate synthase activity
BF39_4992	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_4994	COG4548	von Willebrand factor, type A
BF39_4995	COG0714	Associated with various cellular activities
BF39_4996	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_5	COG1620	l-lactate permease
BF39_50	COG0277	FAD linked oxidase domain protein
BF39_5000	COG0531	amino acid
BF39_5001	COG2188	Transcriptional regulator
BF39_5002	COG1263	PTS System
BF39_5002	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_5003	COG0366	Alpha amylase catalytic
BF39_5007	COG0697	spore germination
BF39_5009	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_5010	COG1115	amino acid carrier protein
BF39_5011	COG1126	abc transporter atp-binding protein
BF39_5012	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_5013	COG0765	amino acid transport
BF39_5014	COG0765	amino acid transport
BF39_5015	COG0833	amino acid
BF39_502	COG0534	Mate efflux family protein
BF39_5020	COG2378	regulation of single-species biofilm formation
BF39_5021	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF39_5022	COG5002	protein histidine kinase activity
BF39_5025	COG0659	secondary active sulfate transmembrane transporter activity
BF39_5028	COG0747	negative chemotaxis
BF39_503	COG0534	Mate efflux family protein
BF39_5030	COG0601	transmembrane transport
BF39_5031	COG4608	Belongs to the ABC transporter superfamily
BF39_5033	COG2271	Major facilitator Superfamily
BF39_5034	COG1846	Transcriptional regulator
BF39_5035	COG0477	Major facilitator Superfamily
BF39_5036	COG0477	Major facilitator Superfamily
BF39_5037	COG1609	Transcriptional regulator
BF39_5038	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF39_504	COG3340	Belongs to the peptidase S51 family
BF39_5040	COG1129	ABC transporter
BF39_5041	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF39_5042	COG1879	ABC-type sugar transport system periplasmic component
BF39_5043	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF39_5047	COG1063	alcohol dehydrogenase
BF39_5050	COG3568	Endonuclease Exonuclease Phosphatase
BF39_5055	COG1968	undecaprenyl-diphosphatase activity
BF39_5056	COG0840	transmembrane signaling receptor activity
BF39_5057	COG3584	3D domain protein
BF39_5057	COG1388	LysM domain
BF39_5058	COG1476	TRANSCRIPTIONal
BF39_5061	COG3104	oligopeptide transport
BF39_5063	COG1114	Component of the transport system for branched-chain amino acids
BF39_5066	COG1113	amino acid transport
BF39_5067	COG2252	PERMEase
BF39_5072	COG0475	glutathione-regulated potassium exporter activity
BF39_5072	COG0569	domain protein
BF39_5075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF39_5076	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF39_5077	COG4990	cell redox homeostasis
BF39_508	COG0785	Cytochrome C biogenesis protein
BF39_5080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_5081	COG0697	spore germination
BF39_5082	COG0531	amino acid
BF39_5084	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_5085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_5086	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_5086	COG1918	ferrous iron import across plasma membrane
BF39_5087	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF39_5088	COG0573	inorganic phosphate transmembrane transporter activity
BF39_5089	COG0581	inorganic phosphate transmembrane transporter activity
BF39_5091	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF39_51	COG3835	regulator
BF39_5118	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF39_5122	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF39_5123	COG1116	anion transmembrane transporter activity
BF39_5124	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_5125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_5126	COG0352	thiamine-phosphate diphosphorylase activity
BF39_5127	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_5128	COG2104	thiamine diphosphate biosynthetic process
BF39_5130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_5131	COG0351	phosphomethylpyrimidine kinase
BF39_5138	COG2205	protein histidine kinase activity
BF39_5139	COG2814	Major facilitator Superfamily
BF39_5140	COG1846	Transcriptional regulator
BF39_5143	COG2252	PERMEase
BF39_5144	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_5148	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF39_5149	COG1621	beta-fructofuranosidase activity
BF39_515	COG2733	membrane
BF39_5150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_5150	COG1263	PTS System
BF39_5151	COG1609	Transcriptional regulator
BF39_5153	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_5154	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF39_5162	COG0778	Nitroreductase
BF39_5163	COG2719	SpoVR family
BF39_5168	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF39_5169	COG1937	Protein conserved in bacteria
BF39_5170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_5170	COG0425	Belongs to the sulfur carrier protein TusA family
BF39_5171	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_5171	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_5172	COG0425	Belongs to the sulfur carrier protein TusA family
BF39_5174	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_5176	COG2210	Belongs to the sulfur carrier protein TusA family
BF39_5177	COG0730	response to heat
BF39_5179	COG1316	TRANSCRIPTIONal
BF39_5180	COG0604	alcohol dehydrogenase
BF39_5181	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF39_5184	COG3711	transcriptional antiterminator
BF39_5184	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_5185	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_5186	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_5190	COG3584	3D domain protein
BF39_5190	COG1388	LysM domain
BF39_5191	COG0577	efflux transmembrane transporter activity
BF39_5192	COG1136	(ABC) transporter
BF39_5194	COG5522	Integral membrane protein (intg_mem_TP0381)
BF39_5197	COG1114	Component of the transport system for branched-chain amino acids
BF39_5198	COG3546	catalase activity
BF39_5205	COG0586	Pfam SNARE associated Golgi protein
BF39_5211	COG0531	amino acid
BF39_5212	COG0475	glutathione-regulated potassium exporter activity
BF39_5214	COG1737	Transcriptional regulator
BF39_5216	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_5216	COG1263	PTS System
BF39_5218	COG2259	Doxx family
BF39_522	COG1131	(ABC) transporter
BF39_5221	COG0697	spore germination
BF39_5222	COG1522	sequence-specific DNA binding
BF39_5224	COG2076	Multidrug Resistance protein
BF39_5225	COG2076	Multidrug Resistance protein
BF39_5226	COG1309	transcriptional regulator
BF39_5227	COG2814	Major facilitator Superfamily
BF39_5228	COG1733	regulation of RNA biosynthetic process
BF39_5230	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_5231	COG4533	DNA binding
BF39_5232	COG2211	Major facilitator Superfamily
BF39_5234	COG0693	protein deglycase activity
BF39_5235	COG0753	catalase activity
BF39_5235	COG0693	protein deglycase activity
BF39_5237	COG0531	amino acid
BF39_5238	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF39_5240	COG1012	belongs to the aldehyde dehydrogenase family
BF39_5241	COG1132	(ABC) transporter
BF39_5242	COG1132	(ABC) transporter
BF39_5243	COG1132	(ABC) transporter
BF39_5244	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_5245	COG0765	amino acid transport
BF39_5246	COG1126	abc transporter atp-binding protein
BF39_5249	COG0189	ligase activity
BF39_525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_5255	COG0028	Belongs to the TPP enzyme family
BF39_5256	COG3527	Alpha-acetolactate decarboxylase
BF39_5259	COG0561	phosphatase activity
BF39_526	COG0528	UMP kinase activity
BF39_5261	COG3409	Peptidoglycan-binding domain 1 protein
BF39_5261	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_5263	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF39_5266	COG0659	secondary active sulfate transmembrane transporter activity
BF39_5270	COG0653	protein targeting
BF39_5271	COG2244	polysaccharide biosynthetic process
BF39_5273	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_5274	COG4196	transglutaminase domain protein
BF39_5277	COG1696	Membrane protein involved in D-alanine export
BF39_528	COG1027	Aspartate ammonia-lyase
BF39_5280	COG1024	Enoyl-CoA hydratase
BF39_5283	COG1363	Peptidase, m42
BF39_5287	COG3938	Belongs to the proline racemase family
BF39_529	COG0281	malic enzyme
BF39_5294	COG0601	transmembrane transport
BF39_5295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_5296	COG0444	Belongs to the ABC transporter superfamily
BF39_5297	COG0444	Belongs to the ABC transporter superfamily
BF39_5298	COG4608	Belongs to the ABC transporter superfamily
BF39_53	COG0745	RESPONSE REGULATOR receiver
BF39_530	COG4191	Histidine kinase
BF39_5304	COG0477	Major facilitator Superfamily
BF39_5305	COG3290	protein histidine kinase activity
BF39_5306	COG4565	transcriptional regulatory protein
BF39_5307	COG3181	Tripartite tricarboxylate transporter family receptor
BF39_531	COG0784	Response regulator, receiver
BF39_5312	COG4978	Transcriptional regulator
BF39_5312	COG0789	Transcriptional regulator
BF39_5315	COG0305	Participates in initiation and elongation during chromosome replication
BF39_5323	COG0477	Major facilitator Superfamily
BF39_533	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_5333	COG3320	Male sterility
BF39_5333	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF39_5338	COG1183	phosphatidylcholine synthase activity
BF39_5342	COG2376	Dihydroxyacetone kinase
BF39_5344	COG2376	Dihydroxyacetone kinase
BF39_5345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_5346	COG1959	2 iron, 2 sulfur cluster binding
BF39_5352	COG3437	response regulator, receiver
BF39_5352	COG2770	Histidine kinase
BF39_5362	COG3237	CsbD-like
BF39_5367	COG1191	sigma factor activity
BF39_5369	COG2208	phosphoserine phosphatase activity
BF39_5370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF39_5371	COG2198	Histidine kinase
BF39_5371	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_5371	COG0784	Response regulator, receiver
BF39_5371	COG2205	protein histidine kinase activity
BF39_5376	COG0393	Putative heavy-metal-binding
BF39_5382	COG0420	3'-5' exonuclease activity
BF39_5383	COG4717	serine-type aminopeptidase activity
BF39_5387	COG1309	transcriptional regulator
BF39_5388	COG2814	Major facilitator Superfamily
BF39_5389	COG0346	lactoylglutathione lyase activity
BF39_5390	COG0346	lactoylglutathione lyase activity
BF39_5391	COG0457	Tetratricopeptide repeat
BF39_5393	COG2267	carboxylic ester hydrolase activity
BF39_5397	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF39_5398	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF39_54	COG5002	protein histidine kinase activity
BF39_5400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF39_5408	COG0477	Major facilitator Superfamily
BF39_5409	COG0477	Major facilitator Superfamily
BF39_5411	COG3973	AAA domain
BF39_5412	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_5416	COG4980	gas vesicle protein
BF39_5417	COG0537	adenosine 5'-monophosphoramidase activity
BF39_5418	COG1131	(ABC) transporter
BF39_5419	COG4473	ABC transporter
BF39_5422	COG1309	transcriptional regulator
BF39_5424	COG3402	PFAM membrane-flanked domain
BF39_5426	COG3428	Bacterial PH domain
BF39_5436	COG3402	PFAM membrane-flanked domain
BF39_5437	COG3428	Bacterial PH domain
BF39_5438	COG2329	Antibiotic biosynthesis monooxygenase
BF39_5439	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_544	COG1051	belongs to the nudix hydrolase family
BF39_5440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF39_5449	COG1309	transcriptional regulator
BF39_545	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_5450	COG1511	domain protein
BF39_5455	COG1609	Transcriptional regulator
BF39_5457	COG1234	tRNA 3'-trailer cleavage
BF39_5458	COG0095	Lipoate-protein ligase
BF39_5460	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_5466	COG3209	COG3209 Rhs family protein
BF39_5473	COG1408	metallophosphoesterase
BF39_5474	COG1078	dGTPase activity
BF39_5476	COG1595	DNA-templated transcription, initiation
BF39_5477	COG2207	Transcriptional regulator
BF39_5477	COG3708	Transcriptional regulator
BF39_5480	COG2205	protein histidine kinase activity
BF39_5481	COG0745	RESPONSE REGULATOR receiver
BF39_5486	COG0501	Belongs to the peptidase M48B family
BF39_5487	COG0840	transmembrane signaling receptor activity
BF39_5488	COG0697	spore germination
BF39_5491	COG0497	DNA recombination
BF39_5492	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF39_5493	COG2224	Isocitrate lyase
BF39_5495	COG1278	Cold shock
BF39_5498	COG4903	ComK protein
BF39_5499	COG0398	Pfam SNARE associated Golgi protein
BF39_55	COG2186	Transcriptional regulator
BF39_550	COG1966	Carbon starvation protein
BF39_5502	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF39_5503	COG1074	ATP-dependent DNA helicase activity
BF39_5511	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF39_5516	COG0367	asparagine synthase
BF39_5518	COG0753	catalase activity
BF39_5519	COG0004	ammonium transporteR
BF39_552	COG0477	Major facilitator Superfamily
BF39_5523	COG2996	Protein conserved in bacteria
BF39_5525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_5527	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_553	COG0477	Major facilitator Superfamily
BF39_5530	COG0561	phosphatase activity
BF39_5532	COG0542	response to heat
BF39_5534	COG2267	carboxylic ester hydrolase activity
BF39_5537	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_5538	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF39_5539	COG5504	Zn-dependent protease
BF39_554	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_5541	COG0180	Tryptophanyl-tRNA synthetase
BF39_5543	COG4166	transmembrane transport
BF39_5544	COG0601	transmembrane transport
BF39_5545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_5546	COG0444	Belongs to the ABC transporter superfamily
BF39_5547	COG4608	Belongs to the ABC transporter superfamily
BF39_5548	COG0534	Mate efflux family protein
BF39_5549	COG4166	transmembrane transport
BF39_5551	COG1393	Belongs to the ArsC family
BF39_5552	COG0861	Integral membrane protein TerC family
BF39_5553	COG4862	establishment of competence for transformation
BF39_5554	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_5556	COG1164	Oligoendopeptidase f
BF39_5559	COG2346	COG2346, Truncated hemoglobins
BF39_556	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF39_5560	COG4116	CYTH
BF39_5562	COG2357	RelA SpoT domain protein
BF39_5563	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF39_5564	COG0564	pseudouridine synthase activity
BF39_5567	COG0772	Belongs to the SEDS family
BF39_5568	COG0772	Belongs to the SEDS family
BF39_5569	COG1216	Glycosyl transferase, family 2
BF39_5573	COG0457	Tetratricopeptide repeat
BF39_5573	COG0463	Glycosyl transferase, family 2
BF39_5577	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF39_558	COG4166	transmembrane transport
BF39_5580	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF39_5588	COG2153	protein acetylation
BF39_5589	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF39_559	COG2223	nitrite transmembrane transporter activity
BF39_5590	COG2382	esterase
BF39_5593	COG5492	domain, Protein
BF39_5594	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_5596	COG0512	Glutamine amidotransferase of anthranilate synthase
BF39_5596	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF39_560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_5612	COG2002	toxin-antitoxin pair type II binding
BF39_5614	COG4974	Belongs to the 'phage' integrase family
BF39_5623	COG2801	Transposase and inactivated derivatives
BF39_5624	COG2801	Transposase and inactivated derivatives
BF39_5627	COG2801	Transposase and inactivated derivatives
BF39_563	COG2244	polysaccharide biosynthetic process
BF39_5630	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF39_5632	COG4974	Belongs to the 'phage' integrase family
BF39_5637	COG0457	Tetratricopeptide repeat
BF39_5639	COG1923	regulation of RNA biosynthetic process
BF39_564	COG0733	neurotransmitter:sodium symporter activity
BF39_566	COG5566	PFAM Mor transcription activator
BF39_5660	COG3344	reverse transcriptase
BF39_567	COG2323	membrane
BF39_5681	COG3344	reverse transcriptase
BF39_570	COG2084	Dehydrogenase
BF39_5727	COG4962	Type ii secretion system protein e
BF39_574	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_5757	COG2311	Membrane
BF39_576	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_5763	COG4196	transglutaminase domain protein
BF39_5764	COG0671	phosphoesterase, PA-phosphatase related
BF39_5768	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF39_5769	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF39_577	COG0028	Belongs to the TPP enzyme family
BF39_5770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF39_5776	COG2801	Transposase and inactivated derivatives
BF39_578	COG0440	acetolactate synthase activity
BF39_579	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF39_581	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF39_5832	COG0791	NLP P60 protein
BF39_5832	COG0741	lytic transglycosylase activity
BF39_5846	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF39_5847	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF39_5857	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF39_586	COG2814	Major facilitator Superfamily
BF39_5860	COG4166	transmembrane transport
BF39_5866	COG1280	lysine exporter protein (LysE YggA)
BF39_587	COG3384	dioxygenase
BF39_5874	COG0681	Belongs to the peptidase S26 family
BF39_589	COG3279	Response regulator of the LytR AlgR family
BF39_5892	COG1309	transcriptional regulator
BF39_5893	COG1683	Conserved Protein
BF39_59	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF39_590	COG0427	acetyl-CoA hydrolase
BF39_5900	COG2801	Transposase and inactivated derivatives
BF39_5904	COG1192	Involved in chromosome partitioning
BF39_595	COG1073	alpha beta
BF39_596	COG4166	transmembrane transport
BF39_6	COG5634	Uncharacterized conserved protein (DUF2278)
BF39_602	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_607	COG1914	H( )-stimulated, divalent metal cation uptake system
BF39_61	COG2116	formate transmembrane transporter activity
BF39_610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF39_612	COG0531	amino acid
BF39_613	COG0531	amino acid
BF39_618	COG2390	Transcriptional regulator
BF39_62	COG0861	Integral membrane protein TerC family
BF39_620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_621	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF39_623	COG4224	UPF0291 protein
BF39_627	COG0006	proline dipeptidase activity
BF39_628	COG2132	Multicopper oxidase
BF39_629	COG2132	Multicopper oxidase
BF39_635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_636	COG1114	Component of the transport system for branched-chain amino acids
BF39_637	COG1114	Component of the transport system for branched-chain amino acids
BF39_639	COG1276	copper resistance
BF39_639	COG2372	response to copper ion
BF39_640	COG4549	nuclear export factor GLE1
BF39_642	COG0697	spore germination
BF39_643	COG0583	DNA-binding transcription factor activity
BF39_644	COG1959	2 iron, 2 sulfur cluster binding
BF39_645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF39_646	COG0778	Nitroreductase
BF39_649	COG0628	permease
BF39_650	COG0039	L-malate dehydrogenase activity
BF39_651	COG1231	oxidoreductase activity
BF39_652	COG0523	cobalamin synthesis protein
BF39_655	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_656	COG2030	dehydratase
BF39_657	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_659	COG0411	ABC transporter
BF39_66	COG2030	dehydratase
BF39_663	COG0583	DNA-binding transcription factor activity
BF39_667	COG1846	Transcriptional regulator
BF39_669	COG1271	oxidase subunit
BF39_670	COG1294	oxidase, subunit
BF39_671	COG4988	ABC transporter
BF39_672	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF39_676	COG1686	Belongs to the peptidase S11 family
BF39_678	COG1388	LysM domain
BF39_678	COG0791	NLP P60 protein
BF39_680	COG1132	(ABC) transporter
BF39_681	COG1132	(ABC) transporter
BF39_682	COG0745	RESPONSE REGULATOR receiver
BF39_683	COG5002	protein histidine kinase activity
BF39_685	COG0300	oxidoreductase activity
BF39_687	COG0726	polysaccharide deacetylase
BF39_691	COG0460	homoserine dehydrogenase
BF39_696	COG1316	TRANSCRIPTIONal
BF39_698	COG0745	RESPONSE REGULATOR receiver
BF39_699	COG5002	protein histidine kinase activity
BF39_70	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_700	COG0726	polysaccharide deacetylase
BF39_702	COG1285	pathogenesis
BF39_703	COG1247	-acetyltransferase
BF39_705	COG4264	IucA IucC family
BF39_706	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_709	COG1082	Xylose isomerase domain protein TIM barrel
BF39_71	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF39_711	COG2814	Major facilitator Superfamily
BF39_712	COG2814	Major facilitator Superfamily
BF39_713	COG2814	Major facilitator Superfamily
BF39_714	COG1279	arginine transmembrane transporter activity
BF39_716	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF39_723	COG0577	efflux transmembrane transporter activity
BF39_724	COG0577	efflux transmembrane transporter activity
BF39_725	COG2002	toxin-antitoxin pair type II binding
BF39_726	COG1404	Belongs to the peptidase S8 family
BF39_727	COG0640	Transcriptional regulator
BF39_728	COG0667	Aldo Keto reductase
BF39_729	COG2814	Major facilitator Superfamily
BF39_73	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF39_734	COG0840	transmembrane signaling receptor activity
BF39_737	COG3949	Membrane
BF39_738	COG0783	Belongs to the Dps family
BF39_741	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_743	COG1231	oxidoreductase activity
BF39_745	COG4989	oxidoreductase activity
BF39_746	COG0523	cobalamin synthesis protein
BF39_747	COG0456	acetyltransferase
BF39_757	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF39_757	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF39_759	COG0702	epimerase
BF39_76	COG1840	ABC-type Fe3 transport system, periplasmic component
BF39_761	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF39_763	COG4166	transmembrane transport
BF39_766	COG0406	alpha-ribazole phosphatase activity
BF39_768	COG5337	Spore coat protein CotH
BF39_769	COG1051	belongs to the nudix hydrolase family
BF39_770	COG0586	Pfam SNARE associated Golgi protein
BF39_771	COG2244	polysaccharide biosynthetic process
BF39_773	COG0701	Predicted permease
BF39_774	COG3689	TIGRFAM TIGR03943 family protein
BF39_775	COG1607	acyl-coa hydrolase
BF39_776	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_779	COG0702	epimerase
BF39_78	COG3842	ATPase activity
BF39_780	COG2839	Protein conserved in bacteria
BF39_781	COG1253	flavin adenine dinucleotide binding
BF39_784	COG1114	Component of the transport system for branched-chain amino acids
BF39_785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_789	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_79	COG3842	ATPase activity
BF39_791	COG1876	peptidase activity
BF39_793	COG0154	amidase activity
BF39_794	COG2211	Major facilitator Superfamily
BF39_798	COG0561	phosphatase activity
BF39_800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF39_804	COG1819	glycosyl
BF39_805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_806	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_812	COG0456	acetyltransferase
BF39_82	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF39_821	COG3874	Sporulation protein YtfJ
BF39_826	COG2226	methyltransferase
BF39_830	COG1082	Xylose isomerase domain protein TIM barrel
BF39_831	COG0346	lactoylglutathione lyase activity
BF39_833	COG0604	alcohol dehydrogenase
BF39_834	COG1595	DNA-templated transcription, initiation
BF39_839	COG0386	Belongs to the glutathione peroxidase family
BF39_840	COG1305	Transglutaminase-like
BF39_841	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF39_842	COG0714	Associated with various cellular activities
BF39_845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF39_846	COG1140	nitrate reductase beta subunit
BF39_847	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF39_848	COG2181	nitrate reductase activity
BF39_85	COG1349	DNA-binding transcription factor activity
BF39_852	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF39_853	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF39_854	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_855	COG0303	'Molybdopterin
BF39_856	COG0314	molybdopterin synthase activity
BF39_858	COG2223	nitrite transmembrane transporter activity
BF39_861	COG1648	precorrin-2 dehydrogenase activity
BF39_863	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF39_863	COG1587	Uroporphyrinogen-III synthase
BF39_864	COG2146	nitrite reductase [NAD(P)H] activity
BF39_865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF39_866	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF39_873	COG2359	stage V sporulation protein S
BF39_876	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_879	COG1418	mRNA catabolic process
BF39_880	COG0488	(ABC) transporter
BF39_883	COG0629	single-stranded DNA binding
BF39_886	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF39_887	COG1413	lyase activity
BF39_890	COG2136	Putative SAM-dependent methyltransferase
BF39_890	COG2521	methyltransferase
BF39_891	COG0018	arginyl-trna synthetase
BF39_897	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF39_90	COG0235	Class ii aldolase
BF39_900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF39_901	COG0017	Asparaginyl-tRNA synthetase
BF39_905	COG1674	ftsk spoiiie
BF39_924	COG1929	Belongs to the glycerate kinase type-1 family
BF39_925	COG0471	metal ion transport
BF39_926	COG0745	RESPONSE REGULATOR receiver
BF39_927	COG3850	Histidine kinase
BF39_927	COG5002	protein histidine kinase activity
BF39_93	COG2861	carbohydrate metabolic process
BF39_930	COG0733	neurotransmitter:sodium symporter activity
BF39_936	COG2610	gluconate transmembrane transporter activity
BF39_937	COG1454	alcohol dehydrogenase
BF39_938	COG1794	racemase activity, acting on amino acids and derivatives
BF39_940	COG0456	acetyltransferase
BF39_942	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF39_944	COG1131	(ABC) transporter
BF39_945	COG4473	ABC transporter
BF39_947	COG0546	phosphoglycolate phosphatase activity
BF39_95	COG3852	Histidine kinase
BF39_951	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_954	COG0768	penicillin binding
BF39_955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_956	COG0204	Acyl-transferase
BF39_957	COG1272	protein, Hemolysin III
BF39_959	COG0805	protein transport
BF39_96	COG1846	Transcriptional regulator
BF39_961	COG1307	EDD domain protein, DegV family
BF39_962	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF39_963	COG1999	signal sequence binding
BF39_964	COG0071	Belongs to the small heat shock protein (HSP20) family
BF39_965	COG0367	asparagine synthase
BF39_969	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_974	COG1335	isochorismatase
BF39_975	COG1051	belongs to the nudix hydrolase family
BF39_977	COG0668	transmembrane transport
BF39_978	COG2203	Gaf domain
BF39_978	COG4585	Histidine kinase
BF39_979	COG2197	response regulator
BF39_98	COG2318	DinB family
BF39_981	COG1737	Transcriptional regulator
BF39_982	COG1064	alcohol dehydrogenase
BF39_989	COG1070	Carbohydrate kinase
BF39_996	COG1125	glycine betaine transport
BF39_996	COG0517	IMP dehydrogenase activity
BF39_997	COG1174	glycine betaine transport