locus-tag class description A16R_00020 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) A16R_00030 ENOG410848D S4 domain protein YaaA A16R_00060 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A16R_00120 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) A16R_00190 ENOG4105ZMH deoxynucleoside kinase A16R_00210 ENOG4105GTG Isochorismatase A16R_00220 ENOG4108Z6B deaminase A16R_00230 ENOG4105C6E dna polymerase iii A16R_00270 ENOG41067KS pro-sigma K processing A16R_00340 ENOG4105CXN decarboxylase A16R_00360 ENOG4105FA2 dna polymerase iii A16R_00370 ENOG4105MA4 psp1 domain protein A16R_00390 ENOG41060K3 Methyltransferase A16R_00410 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) A16R_00420 ENOG4105KRN Transcriptional regulator, abrb family A16R_00440 ENOG4105F8V Hydrolase, tatD family A16R_00450 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) A16R_00470 ENOG4105XFA sporulation peptidase YabG A16R_00480 ENOG4105W42 Veg protein A16R_00510 ENOG4105DFT pur operon repressor A16R_00520 ENOG4105KME endoribonuclease L-psp A16R_00550 ENOG4105C5T Phosphoribosyl pyrophosphate synthase A16R_00560 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) A16R_00580 ENOG4108JA2 transcriptioN-repair coupling factor A16R_00590 ENOG4108M14 stage v sporulation protein t A16R_00610 ENOG4108IY2 MazG family A16R_00620 ENOG41082I2 s4 domain protein A16R_00630 ENOG4105VYY sporulation protein yabp A16R_00660 ENOG41060GV RNA binding s1 domain protein A16R_00700 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) A16R_00710 ENOG4108UGV hypoxanthine phosphoribosyltransferase A16R_00720 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) A16R_00750 ENOG4105C6T cysteine synthase A16R_00760 ENOG4105CRQ synthase (Component I) A16R_00770 ENOG4105DDQ anthranilate synthase A16R_00780 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 A16R_00790 ENOG4105EEI dihydropteroate synthase A16R_00800 ENOG4105KRF dihydroneopterin aldolase A16R_00810 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase A16R_00830 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) A16R_00890 ENOG4108Z0C Uvrb UvrC protein A16R_00920 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) A16R_00940 ENOG4105CTP PilT protein domain protein A16R_00980 ENOG4105D7W serine acetyltransferase A16R_01010 ENOG4105C2N RNA methyltransferase TrmH family group 3 A16R_01020 ENOG4105M0M Tetracycline resistance protein A16R_01030 ENOG4105QIV RNA polymerase A16R_01050 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) A16R_01100 ENOG4107Y49 methyltransferase A16R_01140 ENOG4105XPM ribosomal protein A16R_01350 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) A16R_01400 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) A16R_01420 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A16R_01440 ENOG41067V7 50S ribosomal protein L36 A16R_01500 ENOG4108JJB ABC transporter A16R_01510 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) A16R_01530 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) A16R_01580 ENOG4105D1F ATP-binding protein A16R_01610 ENOG4108NMV polysaccharide deacetylase A16R_01780 ENOG4105C8B TIGR00159 family A16R_01790 ENOG4107U5W ybbr family A16R_01810 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) A16R_01820 ENOG4108VQT Alpha beta hydrolase fold protein A16R_01870 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) A16R_01880 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein A16R_01960 ENOG4108PSK reductase A16R_01970 ENOG4108UMI ABC transporter, permease A16R_01980 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A16R_01990 ENOG4105D01 (LipO)protein A16R_02000 ENOG4105EE1 crotonyl-CoA reductase A16R_02020 ENOG4105IQ5 FAD linked oxidase domain protein A16R_02050 ENOG4105C2C drug resistance transporter, Bcr CflA A16R_02080 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component A16R_02090 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A16R_02100 ENOG4105C3U ABC transporter A16R_02110 ENOG4108JQ7 (ABC) transporter A16R_02170 ENOG4108J59 Extracellular solute-binding protein, family 5 A16R_02180 ENOG4108J59 Extracellular solute-binding protein, family 5 A16R_02200 ENOG4105II7 pyrroline-5-carboxylate reductase A16R_02210 ENOG4107XDY Nicotinamide Mononucleotide Transporter A16R_02230 ENOG4105E0C molybdate abc transporter A16R_02240 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein A16R_02250 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein A16R_02260 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family A16R_02270 ENOG4105EGI Transcriptional regulator A16R_02300 ENOG4105F6E Acyl-transferase A16R_02340 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) A16R_02390 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) A16R_02450 ENOG4105C5H ABC transporter A16R_02490 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein A16R_02510 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A16R_02520 ENOG4105C3U ABC transporter A16R_02530 ENOG4108JQ7 (ABC) transporter A16R_02580 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase A16R_02590 ENOG4105ERH Fumarylacetoacetate hydrolase A16R_02610 ENOG4108SC4 )-transporter A16R_02620 ENOG4105CPF Cell wall formation (By similarity) A16R_02630 ENOG4105CPF Cell wall formation (By similarity) A16R_02640 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) A16R_02670 ENOG4107ZXI Rhomboid family A16R_02690 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein A16R_02700 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) A16R_02720 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) A16R_02910 ENOG4105K8N protein family UPF0079, ATPase A16R_02920 ENOG41072GX Peptidase M22 Glycoprotease A16R_02930 ENOG410801F ribosomal-protein-alanine acetyltransferase A16R_02940 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) A16R_02950 ENOG4105C5H ABC transporter A16R_02980 ENOG4108TYN CAAX amino terminal protease family protein A16R_03050 ENOG4105BZU Histidine kinase A16R_03110 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A16R_03200 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) A16R_03280 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) A16R_03290 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit A16R_03330 ENOG4105VR9 phosphoribosylformylglycinamidine synthase A16R_03390 ENOG4108V3E phosphoribosylglycinamide formyltransferase A16R_03410 ENOG4105C12 Phosphoribosylglycinamide synthetase A16R_03460 ENOG4105C4R Atp-dependent dna helicase A16R_03520 ENOG4108W2Y isochorismatase A16R_03530 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A16R_03540 ENOG4108UMI ABC transporter, permease A16R_03550 ENOG4105D01 (LipO)protein A16R_03600 ENOG410834F Transcriptional regulator A16R_03650 ENOG4105CBD Diacylglycerol kinase A16R_03660 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) A16R_03670 ENOG4108JPW Aminotransferase A16R_03690 ENOG4105C26 Dehydrogenase A16R_03700 ENOG4105KPY Small multidrug resistance protein A16R_03740 ENOG4105D9N nucleoside A16R_03750 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) A16R_03780 ENOG4108W15 Protein of unknown function (DUF1456) A16R_03810 ENOG4105DTQ mandelate racemase muconate lactonizing A16R_03830 ENOG4105DFD Na H antiporter A16R_03870 ENOG4105D3R alkyl hydroperoxide reductase A16R_03880 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) A16R_03900 ENOG4107W7X Aldolase A16R_03910 ENOG4105EHG Permease protein A16R_03920 ENOG4105DQ5 transport system permease protein A16R_03930 ENOG4108V5C ABC transporter A16R_03970 ENOG4106UIA A16R_03980 ENOG4106UIA A16R_04030 ENOG4105BZU Histidine kinase A16R_04070 ENOG410756H nucleotidyltransferase A16R_04080 ENOG4105D2S major facilitator superfamily A16R_04110 ENOG4105E5Q amino acid AbC transporter A16R_04120 ENOG4105EAB amino acid AbC transporter A16R_04140 ENOG4105C8Q Methyl-accepting chemotaxis A16R_04150 ENOG4105C8Q Methyl-accepting chemotaxis A16R_04170 ENOG4105CI1 PTS System A16R_04240 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter A16R_04270 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component A16R_04370 ENOG41062JF Transcriptional regulator A16R_04410 ENOG4105DEU major facilitator superfamily A16R_04440 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) A16R_04470 ENOG4108N0M stress protein A16R_04480 ENOG4106FN3 tellurium resistance protein A16R_04490 ENOG4106FN3 tellurium resistance protein A16R_04500 ENOG4107TS3 membrane protein, TerC A16R_04510 ENOG4108TTB tellurium resistance protein A16R_04550 ENOG4105KJF protein tyrosine phosphatase A16R_04570 ENOG4107U9T Pfam:Ribonuclease_BN A16R_04580 ENOG4105C59 p-type ATPase A16R_04590 ENOG4108IPJ Membrane A16R_04640 ENOG4107ZTW SNARE associated Golgi A16R_04670 ENOG410606W general stress protein A16R_04680 ENOG4105UPD Calcium Proton A16R_04760 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) A16R_04770 ENOG4105VTR Integrase A16R_05330 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) A16R_05350 ENOG4108JUB Transcriptional regulator A16R_05370 ENOG4108IQI permease A16R_05430 ENOG4105CSV Glutaminase A16R_05460 ENOG4108A04 Beta-lactamase A16R_05490 ENOG4105CKK Glycosyl transferase, family 2 A16R_05520 ENOG4105C3I Nad-dependent epimerase dehydratase A16R_05550 ENOG4105F1A Pyruvate formate-lyase A16R_05590 ENOG4105CI2 imidazolone-5-propionate hydrolase A16R_05600 ENOG4105ECP epimerase A16R_05660 ENOG41067AE Membrane-bound metal-dependent hydrolase A16R_05670 ENOG4105CEN a g-specific adenine glycosylase A16R_05680 ENOG4106BXE A16R_05740 ENOG4105BZ1 (ABC) transporter A16R_05750 ENOG4107NBY Membrane A16R_05800 ENOG4108IUW ABC transporter A16R_05840 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen A16R_05850 ENOG4105G5W regulator Fur family A16R_06080 ENOG4108JQC penicillin-binding protein 1A A16R_06120 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) A16R_06140 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) A16R_06150 ENOG4105BZU Histidine kinase A16R_06160 ENOG4105CYN Serine protein kinase A16R_06200 ENOG4105C94 Transporter A16R_06230 ENOG4105DZ6 Band 7 protein A16R_06250 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism A16R_06280 ENOG4105D4T Citrate transporter A16R_06320 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator A16R_06330 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) A16R_06340 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component A16R_06350 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component A16R_06360 ENOG4105BZ7 extracellular solute-binding protein family 1 A16R_06370 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) A16R_06380 ENOG4108STX response regulator A16R_06390 ENOG4105US7 Histidine kinase A16R_06440 ENOG4108MRH transcriptional regulatory protein A16R_06460 ENOG4105C6K Malic enzyme A16R_06480 ENOG4108UZ3 Transporter A16R_06490 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A16R_06510 ENOG4105BZU Histidine kinase A16R_06520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_06540 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) A16R_06550 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) A16R_06560 ENOG4108JB9 formate dehydrogenase A16R_06610 ENOG4105CUB amino acid A16R_06630 ENOG4105C59 p-type ATPase A16R_06640 ENOG4105DAP Nicotinate phosphoribosyltransferase A16R_06710 ENOG41073R8 VanW family A16R_06720 ENOG4108KGH TRANSCRIPTIONal A16R_06730 ENOG4105D9N nucleoside A16R_06750 ENOG4105C37 (CBS) domain A16R_06760 ENOG4108IJ0 Aspartate ammonia-lyase A16R_06770 ENOG4105DAA L-lactate A16R_06800 ENOG4105DUX Transporter A16R_06810 ENOG4108MES Periplasmic binding protein A16R_06820 ENOG4105DQ5 transport system permease protein A16R_06830 ENOG4108IHU transport system permease protein A16R_06840 ENOG4105E0A ABC, transporter A16R_06850 ENOG4105DMQ Methyltransferase A16R_06870 ENOG4105EXW epimerase dehydratase A16R_06890 ENOG4107T89 von Willebrand factor, type A A16R_06900 ENOG4105GMT ATPase associated with various cellular activities aaa_5 A16R_06910 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) A16R_06940 ENOG4105BZU Histidine kinase A16R_06950 ENOG4105D5Q Arginine ornithine antiporter A16R_06960 ENOG4107414 GntR family transcriptional regulator A16R_06970 ENOG4105C5Y PTS System A16R_06980 ENOG4105CG3 alpha amylase, catalytic region A16R_07020 ENOG4105E1K spore germination protein A16R_07040 ENOG4105CRN Aminoglycoside phosphotransferase A16R_07050 ENOG4105BZG amino acid carrier protein A16R_07060 ENOG4105CDA abc transporter atp-binding protein A16R_07070 ENOG4105CT1 (ABC) transporter A16R_07080 ENOG4105EAD ABC transporter A16R_07090 ENOG4105DRP amino acid AbC transporter A16R_07100 ENOG4108IQI permease A16R_07150 ENOG4105D29 Helix-turn-helix type 11 domain protein A16R_07160 ENOG4105NAE bifunctional deaminase-reductase domain protein A16R_07170 ENOG4105BZU Histidine kinase A16R_07210 ENOG4105CHH sulfate transporter A16R_07220 ENOG41068KF Universal stress protein A16R_07240 ENOG4105DEF Extracellular solute-binding protein, family 5 A16R_07260 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component A16R_07270 ENOG4108JQ7 (ABC) transporter A16R_07290 ENOG4105CXY transporter A16R_07300 ENOG41067TZ transcriptional regulator, MarR family A16R_07310 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_07320 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_07330 ENOG4105ETE Transcriptional regulator (LacI family A16R_07340 ENOG4108RVA ribokinase A16R_07360 ENOG4105C2J ABC transporter A16R_07370 ENOG4105CNN ABC, transporter A16R_07380 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator A16R_07390 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) A16R_07520 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) A16R_07530 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer A16R_07540 ENOG41069ER domain protein A16R_07550 ENOG4105VZ8 Transcriptional regulator A16R_07560 ENOG4107D63 A16R_07580 ENOG4105DUX Transporter A16R_07620 ENOG4105C85 amino acid A16R_07630 ENOG4105C7N Xanthine uracil vitamin C permease A16R_07710 ENOG4105BZ9 Cytochrome C oxidase, subunit I A16R_07720 ENOG4105E2S oxidase) subunit II A16R_07750 ENOG4106CAD Protein of unknown function (DUF3311) A16R_07760 ENOG4105E1V na solute symporter A16R_07840 ENOG4105CE1 Ferrous iron transport protein b A16R_07850 ENOG4105CE1 Ferrous iron transport protein b A16R_07860 ENOG4105CVA phosphate A16R_07870 ENOG4105C8U phosphate abc transporter A16R_07880 ENOG4105E2Z phosphate ABC transporter (Permease A16R_08130 ENOG41080XQ Signal transduction protein with cbs domains A16R_08180 ENOG4105ETU transcriptional activator (TenA A16R_08200 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component A16R_08220 ENOG4108VEU Thiamine monophosphate synthase A16R_08230 ENOG41080HI glycine oxidase A16R_08260 ENOG4105D06 uba thif-type nad fad binding protein A16R_08270 ENOG4105DWF phosphomethylpyrimidine kinase A16R_08360 ENOG4108INS Transcriptional regulator A16R_08390 ENOG4105C7N Xanthine uracil vitamin C permease A16R_08460 ENOG4105C5Y PTS System A16R_08590 ENOG4107Y03 Nitroreductase A16R_08600 ENOG4105ED1 spovr family A16R_08660 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase A16R_08670 ENOG4105XTG Pfam:DUF156 A16R_08680 ENOG4105VFE sira family A16R_08690 ENOG4107TPS domain protein A16R_08700 ENOG4105VFE sira family A16R_08710 ENOG41085GJ domain protein A16R_08730 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase A16R_08740 ENOG41087NI Sulfite exporter TauE/SafE A16R_08760 ENOG4108KGH TRANSCRIPTIONal A16R_08830 ENOG4105EMD TRANSCRIPTIONal A16R_08840 ENOG4105VCP PTS System A16R_08850 ENOG4105VZJ PTS System A16R_08910 ENOG4107RBB ABC transporter, permease A16R_08920 ENOG4105C19 ABC transporter A16R_08990 ENOG4105WEF catalase A16R_09060 ENOG4107T5V SNARE associated Golgi A16R_09130 ENOG4105CUB amino acid A16R_09140 ENOG4107RWR Sodium hydrogen exchanger A16R_09160 ENOG4106KNT transcriptional regulator A16R_09230 ENOG4108PCN EamA-like transporter family A16R_09240 ENOG4108YXU transcriptional regulator AsnC family A16R_09260 ENOG4105KPY Small multidrug resistance protein A16R_09270 ENOG4105KPY Small multidrug resistance protein A16R_09320 ENOG4105NF4 modulator of drug activity A16R_09330 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) A16R_09340 ENOG4105E5W Transporter A16R_09360 ENOG4107RKG DJ-1/PfpI family A16R_09370 ENOG4105CH6 catalase A16R_09390 ENOG4105D5Q Arginine ornithine antiporter A16R_09400 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) A16R_09420 ENOG4105C26 Dehydrogenase A16R_09430 ENOG4105BZ1 (ABC) transporter A16R_09470 ENOG4105DRP amino acid AbC transporter A16R_09480 ENOG4105CDA abc transporter atp-binding protein A16R_09510 ENOG410839P A16R_09580 ENOG4107FQX Alpha-acetolactate decarboxylase A16R_09690 ENOG4105CHH sulfate transporter A16R_09780 ENOG4106AKK s-layer domain-containing protein A16R_09800 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein A16R_09810 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein A16R_09850 ENOG4105CGU Enoyl-CoA hydratase A16R_09880 ENOG4105DER m42 family A16R_09920 ENOG4105CTU Proline racemase A16R_10010 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A16R_10040 ENOG4108JQ7 (ABC) transporter A16R_10100 ENOG4105CSH Transporter A16R_10120 ENOG4108MRH transcriptional regulatory protein A16R_10230 ENOG4105CDU Replicative dna helicase A16R_10300 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_10390 ENOG4107P5I polyketide synthase A16R_10400 ENOG4108IG5 Transcriptional regulator A16R_10440 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase A16R_10480 ENOG4105CMT Dihydroxyacetone kinase A16R_10500 ENOG4105CMT Dihydroxyacetone kinase A16R_10510 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A16R_10520 ENOG410847I Transcriptional regulator, BadM Rrf2 family A16R_10590 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase A16R_10720 ENOG4105WN5 stage II sporulation protein A16R_10740 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_10760 ENOG4108MJI response regulator A16R_10770 ENOG4105BZU Histidine kinase A16R_10780 ENOG4105BZU Histidine kinase A16R_10830 ENOG4105K8R UPF0145 protein A16R_10900 ENOG4107VRP DNA repair exonuclease A16R_10910 ENOG4106D4I domain protein A16R_10920 ENOG4105D7V transposase A16R_10950 ENOG4108IND Tetr family transcriptional regulator A16R_10960 ENOG4105EQ0 Major Facilitator superfamily A16R_11010 ENOG4108MUZ hydrolase A16R_11050 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator A16R_11090 ENOG4105C6V Glycerol-3-phosphate dehydrogenase A16R_11120 ENOG4105EMN RNA polymerase sigma factor A16R_11170 ENOG4105C57 major facilitator superfamily A16R_11180 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_11200 ENOG4105EEM helicase A16R_11210 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) A16R_11260 ENOG4105K59 histidine triad (HIT) protein A16R_11330 ENOG410905X membrane-flanked domain protein A16R_11350 ENOG4105CKV Membrane A16R_11430 ENOG410905X membrane-flanked domain protein A16R_11440 ENOG4105CKV Membrane A16R_11450 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation A16R_11460 ENOG4105BZ4 penicillin-binding protein A16R_11470 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) A16R_11490 ENOG4105C1Q protoporphyrinogen oxidase A16R_11540 ENOG4105NA0 Transcriptional regulator A16R_11570 ENOG4105ECB domain protein A16R_11630 ENOG4106AXD A16R_11640 ENOG4108RQ5 Beta-lactamase domain-containing protein A16R_11650 ENOG4105DF9 Lipoate-protein, ligase A16R_11670 ENOG4105CEY Amp-dependent synthetase and ligase A16R_11730 ENOG4105CNA YD repeat protein A16R_11810 ENOG4105ENX hydrolase A16R_11830 ENOG4107RN3 metallophosphoesterase A16R_11840 ENOG4107TVP HD domain protein A16R_11870 ENOG4108AEY RNA polymerase sigma factor A16R_11880 ENOG41086D8 Transcriptional regulator A16R_11920 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A16R_11970 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 A16R_11980 ENOG4105C8Q Methyl-accepting chemotaxis A16R_12030 ENOG4105ZU5 s-layer protein A16R_12040 ENOG4107QP3 malate synthase g A16R_12070 ENOG4105VEQ Cold shock protein A16R_12100 ENOG4105XVF Competence transcription factor A16R_12130 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination A16R_12140 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation A16R_12230 ENOG4105ERH Fumarylacetoacetate hydrolase A16R_12300 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) A16R_12310 ENOG4105CH6 catalase A16R_12370 ENOG4105QNR S1 RNA binding domain protein A16R_12390 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) A16R_12410 ENOG4107AYK membrAne A16R_12420 ENOG41073B9 A16R_12440 ENOG4108KP7 hydrolase A16R_12470 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A16R_12520 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) A16R_12530 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) A16R_12560 ENOG4105C31 Tryptophanyl-tRNA synthetase A16R_12590 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component A16R_12600 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A16R_12620 ENOG4108JQ7 (ABC) transporter A16R_12630 ENOG4105UQX Mate efflux family protein A16R_12690 ENOG4108ZCF integral membrane protein A16R_12710 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) A16R_12770 ENOG4108Z18 K06886 hemoglobin A16R_12780 ENOG4105MIX Adenylate cyclase A16R_12810 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) A16R_12820 ENOG4105EMS pseudouridine synthase A16R_12880 ENOG4105K64 Glycosyl transferase, family 2 A16R_12930 ENOG4107TVC Glycosyl transferase, family 2 A16R_12970 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) A16R_12980 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase A16R_13000 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase A16R_13120 ENOG4108WVJ 2'-5' rna ligase A16R_13170 ENOG4105CK7 Sodium proline symporter A16R_13190 ENOG4105CRQ synthase (Component I) A16R_13200 ENOG4105DDQ anthranilate synthase A16R_13390 ENOG4105C7S Dehydrogenase A16R_13410 ENOG4105VZ8 Transcriptional regulator A16R_13510 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) A16R_13530 ENOG4105DZ1 carboxypeptidase A16R_13540 ENOG4105VFR signal peptidase A16R_13610 ENOG4105C26 Dehydrogenase A16R_13620 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) A16R_13630 ENOG4105F38 ABC transporter, permease A16R_13640 ENOG4105D38 putrescine abc transporter A16R_13650 ENOG4107RUE extracellular solute-binding protein family 1 A16R_13670 ENOG4105EYF MMPL domain protein A16R_13690 ENOG4108YBP pseudouridine synthase A16R_13710 ENOG4105K4I Scp-like extracellular A16R_13720 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) A16R_13730 ENOG4105CQB FAD linked oxidase domain protein A16R_13760 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_13770 ENOG4105BZU Histidine kinase A16R_13780 ENOG4105JXH GntR family transcriptional regulator A16R_13820 ENOG4106A3R peptidase A16R_13850 ENOG4108QTI )-transporter A16R_13860 ENOG4107TS3 membrane protein, TerC A16R_13870 ENOG4105CZN Potassium uptake protein A16R_13880 ENOG410681C small acid-soluble spore protein A16R_13890 ENOG4108Z7G MaoC domain protein dehydratase A16R_13930 ENOG4105CHR reductase A16R_13950 ENOG4105MWK D-amino acid dehydrogenase, small subunit A16R_13990 ENOG4105C4Y ABC transporter A16R_14020 ENOG4107RCV ABC transporter, permease A16R_14030 ENOG4108KAZ Involved in phosphonate degradation (By similarity) A16R_14060 ENOG4105E98 transcriptional regulator DeoR family A16R_14140 ENOG4105PXI polysaccharide deacetylase A16R_14160 ENOG4105BZU Histidine kinase A16R_14170 ENOG41090MY MarR family Transcriptional regulator A16R_14190 ENOG4106DF1 A16R_14210 ENOG4105BZU Histidine kinase A16R_14230 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase A16R_14240 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) A16R_14320 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) A16R_14360 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) A16R_14370 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family A16R_14380 ENOG4105CZV ABC transporter A16R_14400 ENOG4105CJ1 ABC, transporter A16R_14480 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A A16R_14490 ENOG4105EA8 2-Nitropropane dioxygenase A16R_14500 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD A16R_14520 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein A16R_14570 ENOG4105NQC Flavodoxin A16R_14640 ENOG4107QMU Mate efflux family protein A16R_14650 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) A16R_14710 ENOG4105CZN Potassium uptake protein A16R_14720 ENOG41063Y9 A16R_14730 ENOG4105KBJ sporulation protein ytfj A16R_14780 ENOG4105CM2 brancheD-chain amino acid aminotransferase A16R_14790 ENOG4105C7K acetolactate synthase A16R_14800 ENOG4108ZP8 Acetolactate synthase small subunit A16R_14810 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase A16R_14830 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) A16R_14880 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) A16R_14950 ENOG4107RVV histidinol phosphate phosphatase, hisj family A16R_14980 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase A16R_14990 ENOG4105E0M Sulfatase A16R_15010 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) A16R_15050 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) A16R_15060 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) A16R_15080 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) A16R_15090 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein A16R_15100 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein A16R_15110 ENOG4105C8J )-transporter A16R_15150 ENOG4105DFD Na H antiporter A16R_15190 ENOG4105ENE Histidine kinase A16R_15200 ENOG4105WH1 Two component transcriptional regulator luxr family A16R_15230 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) A16R_15290 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A16R_15330 ENOG4105CJ3 phosphate transporter A16R_15340 ENOG4107GRR phosphate transport regulator A16R_15350 ENOG4105BZ4 penicillin-binding protein A16R_15390 ENOG4105BZU Histidine kinase A16R_15400 ENOG4105I3N Conserved Protein A16R_15430 ENOG4105BZU Histidine kinase A16R_15500 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A16R_15510 ENOG4105DZ1 carboxypeptidase A16R_15520 ENOG4108JIC nucleoside recognition domain protein A16R_15540 ENOG4105FE9 pseudouridine synthase A16R_15560 ENOG4107TWT Cytochrome c biogenesis protein A16R_15570 ENOG4105CRE cytochrome C A16R_15580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_15590 ENOG4105BZU Histidine kinase A16R_15600 ENOG4108WBT adenosyltransferase A16R_15630 ENOG4108SAX Membrane A16R_15650 ENOG4105T7X A16R_15660 ENOG4105C9U ATP-dependent DNA helicase RecQ A16R_15670 ENOG4105I7S Abortive infection protein A16R_15710 ENOG4107X2D transcriptional regulator, merr family A16R_15720 ENOG4108S6Z Negative regulator of genetic competence A16R_15770 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase A16R_15780 ENOG4107RB3 L-asparaginase A16R_15840 ENOG4105S2F A16R_15850 ENOG41065D1 A16R_15910 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) A16R_15940 ENOG4105XXQ heptaprenyl diphosphate synthase component I A16R_15960 ENOG4105EAH synthase A16R_16000 ENOG4105CIH Imidazole acetol-phosphate transaminase A16R_16010 ENOG41068YB TPR repeat-containing protein A16R_16040 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) A16R_16050 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) A16R_16060 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit A16R_16130 ENOG4108JYZ YitT family A16R_16140 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase A16R_16170 ENOG4105FJR Lmbe family A16R_16180 ENOG4105CPK Glycosyl transferase (Group 1 A16R_16250 ENOG4105DVT helicase A16R_16260 ENOG4105YAC A16R_16300 ENOG4105CSM endonuclease III A16R_16320 ENOG4105BZ4 penicillin-binding protein A16R_16430 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) A16R_16450 ENOG4105DVT helicase A16R_16460 ENOG4105CTD carboxy-peptidase A16R_16490 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A16R_16520 ENOG4105C2W permease A16R_16530 ENOG4105DHF Membrane A16R_16550 ENOG410890F Dynamin family A16R_16570 ENOG4108W0I acetyltransferase A16R_16590 ENOG4105KHC sulfurtransferase A16R_16620 ENOG4106032 Glutathionylspermidine synthase A16R_16750 ENOG4105CPK Glycosyl transferase (Group 1 A16R_16780 ENOG4108SZE gCN5-related N-acetyltransferase A16R_16820 ENOG41081VK Ribonuclease A16R_16950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) A16R_16970 ENOG4107RWR Sodium hydrogen exchanger A16R_17000 ENOG4108Z5V transcriptional regulator, merr family A16R_17020 ENOG4105H67 Protein of unknown function (DUF421) A16R_17040 ENOG41080C8 DUF218 domain A16R_17150 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) A16R_17170 ENOG4107R0U MotA TolQ exbB proton channel A16R_17180 ENOG4105ER2 Ompa motb domain protein A16R_17190 ENOG4107YTP response regulator receiver protein A16R_17220 ENOG4105DD5 Flagellar motor switch protein A16R_17250 ENOG4105BZU Histidine kinase A16R_17290 ENOG4105E1Q flagellar hook-associated protein A16R_17300 ENOG4105DTJ flagellar hook-associated protein A16R_17350 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) A16R_17360 ENOG4108ZC9 flagellar basal-body rod protein flgc A16R_17370 ENOG41075Z6 flagellar hook-basal body complex protein fliE A16R_17380 ENOG4107U2N Flagellar M-ring protein A16R_17400 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) A16R_17480 ENOG4105BZE flagellar hook protein, FlgE A16R_17550 ENOG4105K64 Glycosyl transferase, family 2 A16R_17620 ENOG4107TVC Glycosyl transferase, family 2 A16R_17670 ENOG4105I03 Flagellin A16R_17680 ENOG4105E4C Lytic transglycosylase catalytic A16R_17720 ENOG4105DD5 Flagellar motor switch protein A16R_17740 ENOG4105CN7 Flagellar biosynthetic protein FliP A16R_17750 ENOG4105VS8 Flagellar biosynthetic protein fliq A16R_17770 ENOG4105D00 flagellar biosynthetic protein flhB A16R_17780 ENOG4105D7B Flagellar biosynthesis protein flha A16R_17810 ENOG4105KTQ flagellar basal-body rod protein A16R_17820 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) A16R_17870 ENOG4108RZE Tetr family transcriptional regulator A16R_17900 ENOG4105KAC Antibiotic biosynthesis monooxygenase A16R_17950 ENOG4105DUM transcriptional regulator, lysR family A16R_17960 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) A16R_17970 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein A16R_17980 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component A16R_17990 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) A16R_18060 ENOG4105CVJ phosphoglycerate mutase A16R_18130 ENOG4105CAQ asparagine synthetase A16R_18170 ENOG4105PGM cation diffusion facilitator family transporter A16R_18190 ENOG4105DRR Transcriptional regulator, GntR family A16R_18200 ENOG4108UZ3 Transporter A16R_18210 ENOG4105CKI cobalamin synthesis protein A16R_18220 ENOG4108PJD permease A16R_18260 ENOG4105DFD Na H antiporter A16R_18270 ENOG4105C9Q fumarate hydratase class II A16R_18330 ENOG4105EC3 peptidase S51, dipeptidase E A16R_18370 ENOG4107QIV Cytochrome c biogenesis protein A16R_18440 ENOG4106BRA Membrane A16R_18510 ENOG4105CJ1 ABC, transporter A16R_18550 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) A16R_18570 ENOG4108IJ0 Aspartate ammonia-lyase A16R_18580 ENOG4105C6K Malic enzyme A16R_18730 ENOG4105FVX A16R_18810 ENOG4105CSR polyphosphate kinase 2 A16R_18860 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) A16R_18900 ENOG4105EU0 Major facilitator Superfamily A16R_18910 ENOG4105C6T cysteine synthase A16R_18950 ENOG4105C8J )-transporter A16R_18970 ENOG4105X5K response regulator receiver protein A16R_18980 ENOG4105H67 Protein of unknown function (DUF421) A16R_19020 ENOG4106KE4 Dehydrogenase A16R_19050 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) A16R_19060 ENOG4105CHR reductase A16R_19070 ENOG4105CM2 brancheD-chain amino acid aminotransferase A16R_19080 ENOG4105C7K acetolactate synthase A16R_19090 ENOG4108ZP8 Acetolactate synthase small subunit A16R_19100 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase A16R_19120 ENOG4105C7B Threonine dehydratase A16R_19170 ENOG4105C6X Major Facilitator A16R_19180 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b A16R_19200 ENOG4105DY9 regulatoR A16R_19210 ENOG4105CYC Transferase A16R_19260 ENOG4108J59 Extracellular solute-binding protein, family 5 A16R_19320 ENOG41068WN A16R_19370 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) A16R_19380 ENOG4105C72 UPF0176 protein A16R_19400 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) A16R_19490 ENOG4107RHR regulatoR A16R_19510 ENOG4105D9N nucleoside A16R_19520 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) A16R_19590 ENOG4107RAQ aminopeptidase A16R_19600 ENOG4107STQ Multicopper oxidase A16R_19720 ENOG4108T5E Copper resistance protein A16R_19730 ENOG4105KTB nuclear export factor GLE1 A16R_19750 ENOG4107RT3 EamA-like transporter family A16R_19760 ENOG4105GZI Transcriptional regulator A16R_19770 ENOG4108Z40 Transcriptional regulator A16R_19780 ENOG4107ZXU DSBA oxidoreductase A16R_19790 ENOG4108TVJ Nitroreductase A16R_19810 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) A16R_19820 ENOG4106F5Q Membrane A16R_19830 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) A16R_19850 ENOG4105CKI cobalamin synthesis protein A16R_19900 ENOG4108Z7G MaoC domain protein dehydratase A16R_19910 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) A16R_19930 ENOG4105C0Z ABC transporter A16R_19940 ENOG4108IV0 ABC, transporter A16R_19950 ENOG4105C32 Amino acid ABC transporter (Permease) A16R_19970 ENOG4105SKE transcriptional Regulator LysR family A16R_20010 ENOG4105YGB Transcriptional regulator A16R_20030 ENOG4105C4M (Ubiquinol oxidase) subunit I A16R_20040 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A16R_20050 ENOG4108JJ9 ABC, transporter A16R_20060 ENOG4108JJ8 (ABC) transporter A16R_20140 ENOG4105BZ1 (ABC) transporter A16R_20150 ENOG4105BZ1 (ABC) transporter A16R_20160 ENOG4105EFI regulatoR A16R_20170 ENOG4105BZU Histidine kinase A16R_20230 ENOG4108ZJ4 polysaccharide deacetylase A16R_20280 ENOG4105D6E homoserine dehydrogenase A16R_20340 ENOG4108KGH TRANSCRIPTIONal A16R_20360 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A16R_20370 ENOG4105BZU Histidine kinase A16R_20380 ENOG4107VMI polysaccharide deacetylase A16R_20400 ENOG4105KT7 mgtC SapB transporter A16R_20410 ENOG4105VRR gCN5-related N-acetyltransferase A16R_20430 ENOG4105DUU IucA IucC family protein A16R_20440 ENOG4105CEY Amp-dependent synthetase and ligase A16R_20480 ENOG4108WBH protein TIM barrel A16R_20490 ENOG4105YWU small acid-soluble spore protein A16R_20530 ENOG4108ZUB Lysine exporter protein (Lyse ygga) A16R_20670 ENOG4105KRN Transcriptional regulator, abrb family A16R_20690 ENOG4105YVS arsR family transcriptional regulator A16R_20700 ENOG4107SET aldo keto reductase A16R_20710 ENOG4107XZQ multidrug resistance protein A16R_20760 ENOG4105C8Q Methyl-accepting chemotaxis A16R_20790 ENOG4108K88 Membrane A16R_20800 ENOG4108WPJ Ferritin-like domain A16R_20830 ENOG4105DEN Luciferase family A16R_20870 ENOG4107QM2 Aldo Keto reductase A16R_20880 ENOG4105CKI cobalamin synthesis protein A16R_20980 ENOG4105DSE periplasmic solute binding protein A16R_21000 ENOG4105K4T epimerase A16R_21020 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A16R_21070 ENOG4105CVJ phosphoglycerate mutase A16R_21110 ENOG4107T5V SNARE associated Golgi A16R_21140 ENOG4108PJD permease A16R_21160 ENOG4108S4H thioesterase Superfamily protein A16R_21170 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) A16R_21220 ENOG4105SXS Protein of unknown function (DUF456) A16R_21230 ENOG4105C37 (CBS) domain A16R_21270 ENOG4108Z7R Chaperone CsaA A16R_21300 ENOG4108ZRV stage ii sporulation protein p A16R_21320 ENOG4108VXD carboxy-peptidase A16R_21340 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) A16R_21390 ENOG4108X4Q Hydrolase A16R_21410 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) A16R_21420 ENOG4107RBS Methyltransferase A16R_21450 ENOG41087PP glycosyltransferase MGT family A16R_21460 ENOG4108JYZ YitT family A16R_21470 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A16R_21540 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) A16R_21630 ENOG4105KBJ sporulation protein ytfj A16R_21680 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) A16R_21720 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) A16R_21730 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_21750 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein A16R_21760 ENOG4105EMN RNA polymerase sigma factor A16R_21820 ENOG4108V06 Glutathione peroxidase A16R_21850 ENOG4105C7R Atpase associated with various cellular activities aaa_3 A16R_21890 ENOG4108IUE nitrate reductase beta subunit A16R_21900 ENOG4105R3A Nitrate reductase A16R_21950 ENOG4107V6Q Cyclic nucleotide-binding domain A16R_21960 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) A16R_21970 ENOG4105D06 uba thif-type nad fad binding protein A16R_21980 ENOG4105CVM Molybdenum cofactor synthesis domain protein A16R_21990 ENOG4108ZAF Molybdopterin A16R_22040 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein A16R_22050 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein A16R_22060 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) A16R_22070 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit A16R_22080 ENOG4108IFG nitrite reductase, (NAD(P)H) A16R_22090 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) A16R_22170 ENOG4105MCT stage V sporulation protein S A16R_22190 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase A16R_22240 ENOG4105C5H ABC transporter A16R_22270 ENOG4108UUM single-stranded DNA-binding protein A16R_22300 ENOG41061H0 Monooxygenase A16R_22340 ENOG4107YX5 Pfam:DUF548 A16R_22350 ENOG4105C75 arginyL-tRNA synthetase A16R_22410 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) A16R_22440 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) A16R_22450 ENOG4105C5S asparaginyl-tRNA synthetase A16R_22490 ENOG4105EC2 ftsk spoIIIe A16R_22690 ENOG4105BZW Glycerate kinase A16R_22720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_22730 ENOG41062D9 Histidine kinase A16R_22820 ENOG4107XGZ Hydrolase A16R_22830 ENOG4105CY2 Citrate transporter A16R_22840 ENOG4105C0A alcohol dehydrogenase A16R_22870 ENOG4105KD7 acetyltransferase A16R_22950 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 A16R_22990 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) A16R_23020 ENOG4107RVG penicillin-binding protein A16R_23030 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A16R_23040 ENOG4105E9Q Acyl-transferase A16R_23050 ENOG4108UT2 hemolysin iii A16R_23070 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) A16R_23090 ENOG4108RCR degv family A16R_23100 ENOG4105E8R UPF0173 metal-dependent hydrolase A16R_23110 ENOG4108KF3 Electron transport protein SCO1 SenC A16R_23120 ENOG4107Y70 Heat shock protein A16R_23130 ENOG4105CAQ asparagine synthetase A16R_23170 ENOG4108MES Periplasmic binding protein A16R_23180 ENOG4105F0I Aminotransferase A16R_23250 ENOG4105D8X mechanosensitive ion channel A16R_23260 ENOG4105BZU Histidine kinase A16R_23270 ENOG4105WH1 Two component transcriptional regulator luxr family A16R_23290 ENOG4106KNT transcriptional regulator A16R_23370 ENOG4105CMG Carbohydrate kinase A16R_23380 ENOG4105CMG Carbohydrate kinase A16R_23440 ENOG4108IJ8 ABC transporter A16R_23450 ENOG4105E90 ABC transporter A16R_23520 ENOG4105C37 (CBS) domain A16R_23580 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) A16R_23610 ENOG4107S4Y M20 DapE family protein YgeY A16R_23620 ENOG4108TSC N-acetyltransferase A16R_23630 ENOG4108JUB Transcriptional regulator A16R_23640 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein A16R_23730 ENOG4108N23 SpoOM-related protein A16R_23740 ENOG410841Q phosphoesterase PA-phosphatase related protein A16R_23790 ENOG4108IBT Inherit from COG: transposase A16R_23980 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) A16R_24070 ENOG4105CZM Major Facilitator A16R_24080 ENOG4105W8X HesB YadR YfhF-family protein A16R_24100 ENOG4105DXD 2-methylcitrate dehydratase A16R_24110 ENOG4105CR4 methylisocitrate lyase A16R_24130 ENOG4105C1G acyl-Coa dehydrogenase A16R_24140 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A16R_24160 ENOG4105N14 lysine exporter protein LysE YggA A16R_24170 ENOG4105E39 Enoyl-CoA hydratase A16R_24200 ENOG4107RFY SbcCD D subunit A16R_24210 ENOG4105EYH Exonuclease A16R_24270 ENOG4105FCD Major Facilitator A16R_24280 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase A16R_24290 ENOG4105E4F Isochorismate synthase A16R_24300 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase A16R_24310 ENOG4105WQI isochorismatase A16R_24320 ENOG4105CEY Amp-dependent synthetase and ligase A16R_24330 ENOG4105WQT MbtH domain protein A16R_24340 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_24370 ENOG4105K70 DNA-binding protein A16R_24410 ENOG4105BZG amino acid carrier protein A16R_24450 ENOG4105FE9 pseudouridine synthase A16R_24470 ENOG4105C22 threonyL-tRNA synthetase A16R_24510 ENOG4107SKW Inherit from COG: Alpha beta hydrolase A16R_24570 ENOG4108D32 Methyltransferase A16R_24630 ENOG41081I9 integral membrane protein A16R_24650 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) A16R_24670 ENOG4105EYF MMPL domain protein A16R_24720 ENOG4105WCN acetyltransferase A16R_24780 ENOG4105C1Q protoporphyrinogen oxidase A16R_24800 ENOG41068WN A16R_24820 ENOG4105VEQ Cold shock protein A16R_24870 ENOG410667J hydrolase A16R_24940 ENOG4107V2S Transcriptional regulator A16R_24950 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) A16R_24980 ENOG4105DND Transcriptional regulator A16R_24990 ENOG4108RPX mosc domain containing protein A16R_25030 ENOG4105BZ1 (ABC) transporter A16R_25040 ENOG4105BZ1 (ABC) transporter A16R_25070 ENOG4108JCI Transcriptional regulator A16R_25130 ENOG4108KPJ rna polymerase sigma factor A16R_25200 ENOG4105F32 YngK protein A16R_25250 ENOG4105RD7 BadF BadG BcrA BcrD A16R_25270 ENOG4107STF Involved in phosphonate degradation (By similarity) A16R_25290 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) A16R_25330 ENOG4105C1J atp-dependent rna helicase A16R_25410 ENOG41088CC tellurite resistance protein tehB A16R_25430 ENOG4108I0C methyltransferase A16R_25440 ENOG4107RA9 decarboxylase A16R_25450 ENOG41090HR transcriptional regulator A16R_25550 ENOG4105CIN aminoacyl-histidine dipeptidase A16R_25610 ENOG4107RF6 penicillin-binding protein A16R_25670 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase A16R_25680 ENOG4105ETE Transcriptional regulator (LacI family A16R_25690 ENOG4105IE8 Alpha-ketoglutarate permease A16R_25700 ENOG4105CK5 oxidoreductase A16R_25770 ENOG4105D2N Aldolase A16R_25780 ENOG4105DH8 myo-inositol catabolism A16R_25820 ENOG4105CGH 5'-nucleotidase A16R_25840 ENOG4105CGH 5'-nucleotidase A16R_25870 ENOG4105VZ8 Transcriptional regulator A16R_25890 ENOG4108VXD carboxy-peptidase A16R_25940 ENOG41067SE Tetr family transcriptional regulator A16R_25950 ENOG4105C5H ABC transporter A16R_25970 ENOG4105BZU Histidine kinase A16R_26000 ENOG4106ANW SMI1_KNR4 A16R_26010 ENOG4105CEP NADH dehydrogenase A16R_26020 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) A16R_26050 ENOG4105CJ1 ABC, transporter A16R_26070 ENOG4107Z3H Transcriptional regulator, TetR family A16R_26100 ENOG4105C1G acyl-Coa dehydrogenase A16R_26110 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase A16R_26120 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit A16R_26130 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase A16R_26140 ENOG4105E39 Enoyl-CoA hydratase A16R_26150 ENOG4107QX3 carboxylase A16R_26160 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) A16R_26180 ENOG4105WCN acetyltransferase A16R_26190 ENOG4105DBI uridine monophosphokinase A16R_26220 ENOG4105DZ1 carboxypeptidase A16R_26250 ENOG4105T9C HD domain A16R_26270 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) A16R_26380 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) A16R_26380 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) A16R_26410 ENOG4105FQP Beta-lactamase A16R_26430 ENOG4107Y80 Major Facilitator superfamily A16R_26550 ENOG4105CPQ Dehydrogenase A16R_26580 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) A16R_26590 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) A16R_26820 ENOG4105ETU transcriptional activator (TenA A16R_27060 ENOG410667J hydrolase A16R_27080 ENOG4105BZU Histidine kinase A16R_27150 ENOG4108JJB ABC transporter A16R_27180 ENOG4108HGU Histidine kinase A16R_27210 ENOG4105CB2 alcohol dehydrogenase A16R_27250 ENOG4105FQP Beta-lactamase A16R_27310 ENOG4108V4B ThiJ pfpI A16R_27360 ENOG4107Y80 Major Facilitator superfamily A16R_27390 ENOG4107VXM glycerophosphoryl diester phosphodiesterase A16R_27440 ENOG4107Y9U Membrane A16R_27550 ENOG4105E09 nadh pyrophosphatase A16R_27560 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) A16R_27570 ENOG4108Z4K mutator MutT protein A16R_27640 ENOG4108XI2 Domain of unknown function (DUF1963) A16R_27700 ENOG4105KWG Pfam:DUF1696 A16R_27780 ENOG4105PKS Excinuclease abc c subunit domain protein A16R_27870 ENOG4107VFR oxidoreductase A16R_27920 ENOG4105PAD Hydrolase A16R_27970 ENOG4105DY8 decarboxylase A16R_28010 ENOG4108IUM Glycogen debranching enzyme A16R_28070 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) A16R_28090 ENOG4105FDR Membrane A16R_28180 ENOG4108V3A UPF0421 protein A16R_28230 ENOG4105MSI germination protein ypeb A16R_28270 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) A16R_28300 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) A16R_28310 ENOG4107Z3H Transcriptional regulator, TetR family A16R_28370 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family A16R_28410 ENOG4105E98 transcriptional regulator DeoR family A16R_28450 ENOG41062ES Transcriptional regulator A16R_28500 ENOG4107QKR Dehydrogenase A16R_28520 ENOG4107RUY (E1 component), alpha subunit A16R_28550 ENOG4105E1F short-chain dehydrogenase reductase A16R_28560 ENOG4105RHY Pfam:UPF0157 A16R_28610 ENOG4107SQ8 Glycine betaine A16R_28620 ENOG4108IJ7 Glycine betaine A16R_28670 ENOG4105E66 phosphoriboisomerase A A16R_28680 ENOG41082BV acetyltransferase A16R_28690 ENOG4108M1A Chitin-binding protein A16R_28790 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 A16R_28900 ENOG4105EEM helicase A16R_29030 ENOG4108M1A Chitin-binding protein A16R_29060 ENOG4105BZG amino acid carrier protein A16R_29070 ENOG4105C26 Dehydrogenase A16R_29080 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A16R_29090 ENOG4105CTU Proline racemase A16R_29100 ENOG4105CTU Proline racemase A16R_29110 ENOG41080HI glycine oxidase A16R_29190 ENOG4107T5V SNARE associated Golgi A16R_29220 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD A16R_29260 ENOG4105DTQ mandelate racemase muconate lactonizing A16R_29340 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) A16R_29350 ENOG4105BZU Histidine kinase A16R_29370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_29480 ENOG4105EPR degv family A16R_29560 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) A16R_29570 ENOG4106K7D Major facilitator family transporter A16R_29620 ENOG4107BMA Transglycosylase associated protein A16R_29650 ENOG41089UC methyltransferase, type 11 A16R_29800 ENOG4105DVE abc transporter atp-binding protein A16R_29880 ENOG4105C02 permease A16R_29900 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) A16R_29910 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A16R_29920 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein A16R_29970 ENOG4105E09 nadh pyrophosphatase A16R_30010 ENOG4108AQF aminoglycoside N(3)-acetyltransferase A16R_30120 ENOG4107VC0 DNA alkylation repair enzyme A16R_30150 ENOG4107VMI polysaccharide deacetylase A16R_30170 ENOG4108ZCF integral membrane protein A16R_30180 ENOG4105E0M Sulfatase A16R_30190 ENOG4105C5H ABC transporter A16R_30210 ENOG4105EYF MMPL domain protein A16R_30220 ENOG4105EYF MMPL domain protein A16R_30230 ENOG4105EYF MMPL domain protein A16R_30240 ENOG41082JN Transcriptional regulator A16R_30290 ENOG4105CIH Imidazole acetol-phosphate transaminase A16R_30300 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase A16R_30310 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase A16R_30390 ENOG41069ER domain protein A16R_30410 ENOG4105EMN RNA polymerase sigma factor A16R_30460 ENOG4105D4B ABC, transporter A16R_30490 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane A16R_30510 ENOG4105DKT Transcriptional regulator A16R_30550 ENOG41061GT Aldolase A16R_30600 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) A16R_30660 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) A16R_30670 ENOG4105II7 pyrroline-5-carboxylate reductase A16R_30700 ENOG4107258 Transcriptional regulator A16R_30720 ENOG4105E0Y RtcB Protein A16R_30740 ENOG4105G6Z alkaline phosphatase A16R_30760 ENOG4105VMP Transcriptional regulator A16R_30790 ENOG41090T1 Membrane A16R_30810 ENOG4108WCX response regulator A16R_30830 ENOG41068WN A16R_30880 ENOG4105C7R Atpase associated with various cellular activities aaa_3 A16R_30970 ENOG4105CKK Glycosyl transferase, family 2 A16R_30990 ENOG4105C8Y Acetylornithine aminotransferase A16R_31080 ENOG4105C7R Atpase associated with various cellular activities aaa_3 A16R_31100 ENOG4108TVJ Nitroreductase A16R_31110 ENOG4105FS7 Transcriptional regulator A16R_31200 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family A16R_31220 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) A16R_31280 ENOG4108XET gCN5-related N-acetyltransferase A16R_31440 ENOG410635A Membrane A16R_31450 ENOG4105KNA -acetyltransferase A16R_31460 ENOG4108IQI permease A16R_31480 ENOG4105F1N DNA alkylation repair A16R_31560 ENOG4107RF6 penicillin-binding protein A16R_31590 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) A16R_31670 ENOG4105P4J Allophanate hydrolase, subunit 1 A16R_31680 ENOG4107258 Transcriptional regulator A16R_31700 ENOG4106N3A copper homeostasis protein cutc A16R_31710 ENOG4108ZRV stage ii sporulation protein p A16R_31720 ENOG4108ZHR arsR family transcriptional regulator A16R_31740 ENOG4105FDT acyl-CoA dehydrogenase A16R_31780 ENOG4105DWD nucleoside recognition domain protein A16R_31850 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) A16R_32000 ENOG4105E2A Dehydrogenase A16R_32030 ENOG4108IJ0 Aspartate ammonia-lyase A16R_32040 ENOG4105HDK L-asparaginase A16R_32050 ENOG4108IMY Transcriptional regulator A16R_32070 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) A16R_32080 ENOG4105CUB amino acid A16R_32130 ENOG4105C6K Malic enzyme A16R_32160 ENOG4108NHD germination protein A16R_32170 ENOG4108NHD germination protein A16R_32180 ENOG4108Q8B Spore germination protein A16R_32250 ENOG4105CSV Glutaminase A16R_32330 ENOG4105CGH 5'-nucleotidase A16R_32340 ENOG4105CH6 catalase A16R_32360 ENOG4105CHJ isochorismatase hydrolase A16R_32490 ENOG4108606 TspO/MBR family A16R_32500 ENOG4105CVP deoxyribo-dipyrimidine photolyase A16R_32540 ENOG4108TWJ NADH dehydrogenase subunit 5 A16R_32550 ENOG4105GPN Uncharacterized conserved protein (DUF2294) A16R_32570 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase A16R_32580 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) A16R_32590 ENOG4105DSE periplasmic solute binding protein A16R_32600 ENOG4105CC5 ABC transporter A16R_32610 ENOG4105DIK (ABC) transporter A16R_32670 ENOG4105D6J arsenicaL-resistance protein A16R_32680 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_32690 ENOG41085FC arsR family transcriptional regulator A16R_32720 ENOG4105F7F Chaperone A16R_32740 ENOG4105CHR reductase A16R_32750 ENOG4108YXU transcriptional regulator AsnC family A16R_32890 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) A16R_32910 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_32930 ENOG4105IIP Membrane A16R_32960 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_32970 ENOG41062D9 Histidine kinase A16R_33020 ENOG4105K6H D-cysteine desulfhydrase A16R_33080 ENOG4105VZ8 Transcriptional regulator A16R_33110 ENOG4108NNI Beta-lactamase domain-containing protein A16R_33120 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase A16R_33140 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) A16R_33150 ENOG4105JQZ Methyltransferase A16R_33180 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) A16R_33190 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) A16R_33220 ENOG4105BZU Histidine kinase A16R_33250 ENOG4108U05 Transcriptional regulator A16R_33290 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) A16R_33300 ENOG4105DJB Major Facilitator Superfamily A16R_33310 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) A16R_33320 ENOG4107QR9 Iron-sulfur cluster binding protein A16R_33370 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A A16R_33420 ENOG4105TRI Hydrolase A16R_33500 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) A16R_33570 ENOG4107QJQ Mate efflux family protein A16R_33610 ENOG4105EQ0 Major Facilitator superfamily A16R_33620 ENOG4108JGH Tetr family transcriptional regulator A16R_33640 ENOG4105C44 Serine transporter A16R_33650 ENOG4105EJQ L-serine dehydratase A16R_33680 ENOG4108JPW Aminotransferase A16R_33710 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) A16R_33730 ENOG4105DVH amino acid A16R_33760 ENOG4108JQ1 Dehydrogenase A16R_33810 ENOG4108AEY RNA polymerase sigma factor A16R_33850 ENOG410874W AraC family transcriptional regulator A16R_33890 ENOG4105HIR S-layer domain protein A16R_33970 ENOG4108ISG Major Facilitator A16R_33990 ENOG4107MII Sugar-specific transcriptional regulator TrmB A16R_34000 ENOG4105CZM Major Facilitator A16R_34040 ENOG4105DA5 (ABC) transporter A16R_34050 ENOG41069JR A16R_34080 ENOG4105RXJ A16R_34090 ENOG4105KPY Small multidrug resistance protein A16R_34100 ENOG4105KBX Transcriptional regulator, TetR family A16R_34120 ENOG4105CRW Short chain fatty acid transporter A16R_34140 ENOG4105DYS nad(p)h dehydrogenase (quinone) A16R_34200 ENOG4108JJB ABC transporter A16R_34210 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) A16R_34270 ENOG4108K8S endonuclease I A16R_34300 ENOG41067QW Transcriptional regulator A16R_34320 ENOG4108Z66 YbaK ebsC protein A16R_34330 ENOG4105CUT histidyl-tRNA synthetase A16R_34360 ENOG4105KVH Transcriptional regulator A16R_34370 ENOG4108RCM Nitroreductase A16R_34410 ENOG4108PSK reductase A16R_34430 ENOG4105CJ1 ABC, transporter A16R_34550 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_34560 ENOG4105DKQ ROK family A16R_34590 ENOG4108UW5 maltose o-acetyltransferase A16R_34620 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) A16R_34640 ENOG4105C31 Tryptophanyl-tRNA synthetase A16R_34650 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) A16R_34700 ENOG4105DMQ Methyltransferase A16R_34720 ENOG4105EV4 Multidrug resistance protein mdtH A16R_34780 ENOG4105C37 (CBS) domain A16R_34810 ENOG4105DDN Pentapeptide repeat-containing protein A16R_34820 ENOG4105XDF Protein of unknown function (DUF1272) A16R_34830 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) A16R_34840 ENOG4105CMG Carbohydrate kinase A16R_34850 ENOG4105C6Z Gluconate A16R_34860 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) A16R_34890 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase A16R_34900 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase A16R_34910 ENOG4105CIS alcohol dehydrogenase A16R_34920 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone A16R_34950 ENOG4105EWI Short-chain dehydrogenase reductase Sdr A16R_34960 ENOG4105D4Y metalloprotease A16R_35010 ENOG4105CV8 reductase A16R_35020 ENOG4105F27 Major Facilitator A16R_35050 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) A16R_35060 ENOG4105C44 Serine transporter A16R_35120 ENOG4105KVH Transcriptional regulator A16R_35130 ENOG4108TZY GntR Family Transcriptional Regulator A16R_35160 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase A16R_35170 ENOG4105KVH Transcriptional regulator A16R_35180 ENOG4105KVH Transcriptional regulator A16R_35250 ENOG4105JAB phenazine biosynthesis protein, phzf family A16R_35270 ENOG4105CHR reductase A16R_35320 ENOG4105KVH Transcriptional regulator A16R_35530 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) A16R_35560 ENOG4107YXZ hydrolase, family 25 A16R_35610 ENOG4105ED2 Beta-lactamase A16R_35630 ENOG4105H3G oxidoreductase A16R_35800 ENOG4108TN2 lmbE family A16R_35820 ENOG4107R3E Citrate transporter A16R_35870 ENOG4108MES Periplasmic binding protein A16R_35890 ENOG4105EHG Permease protein A16R_35900 ENOG4105DQ5 transport system permease protein A16R_35910 ENOG4105NX3 Membrane A16R_35920 ENOG4107ZY0 Phenazine biosynthesis-like protein A16R_35960 ENOG4107CUJ Protein of unknown function (DUF2690) A16R_35980 ENOG4107V2S Transcriptional regulator A16R_36020 ENOG4105C98 muts2 protein A16R_36060 ENOG4105E5K Alpha-amylase A16R_36070 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase A16R_36080 ENOG4105DPN Oligoendopeptidase f A16R_36090 ENOG4108A04 Beta-lactamase A16R_36150 ENOG4107VXM glycerophosphoryl diester phosphodiesterase A16R_36180 ENOG41082BM Transcriptional regulator, arsr family A16R_36190 ENOG4105CIS alcohol dehydrogenase A16R_36250 ENOG4105RHY Pfam:UPF0157 A16R_36270 ENOG4105C09 Bile acid A16R_36280 ENOG4105CQB FAD linked oxidase domain protein A16R_36320 ENOG4108UT6 Transferase hexapeptide repeat containing protein A16R_36340 ENOG4105K64 Glycosyl transferase, family 2 A16R_36350 ENOG4105E39 Enoyl-CoA hydratase A16R_36380 ENOG4105KT7 mgtC SapB transporter A16R_36400 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_36410 ENOG41073R8 VanW family A16R_36430 ENOG4108R1P A16R_36470 ENOG4105VEQ Cold shock protein A16R_36510 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) A16R_36550 ENOG410904N short-chain dehydrogenase reductase A16R_36570 ENOG4106IQC argininosuccinate lyase A16R_36600 ENOG4108IA2 Sodium pantothenate symporter A16R_36620 ENOG4105C26 Dehydrogenase A16R_36630 ENOG4105CHR reductase A16R_36650 ENOG4105EWU Squalene--hopene cyclase A16R_36670 ENOG4105FR1 rard protein A16R_36680 ENOG410696E Membrane A16R_36710 ENOG4105D1F ATP-binding protein A16R_36730 ENOG4108ZAF Molybdopterin A16R_36740 ENOG4105CVM Molybdenum cofactor synthesis domain protein A16R_36750 ENOG4105D06 uba thif-type nad fad binding protein A16R_36760 ENOG4105TMB Formate nitrite transporter A16R_36780 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) A16R_36790 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) A16R_36810 ENOG4108JB9 formate dehydrogenase A16R_36820 ENOG4105E1K spore germination protein A16R_36960 ENOG4107QJT sodium dicarboxylate symporter A16R_36970 ENOG4108KGH TRANSCRIPTIONal A16R_36990 ENOG4105EMN RNA polymerase sigma factor A16R_37040 ENOG4105CIG ABC transporter A16R_37060 ENOG4105D9R oxidoreductase A16R_37080 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A16R_37090 ENOG4105K4P CoA-binding domain protein A16R_37100 ENOG4105C0H protease A16R_37110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_37140 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase A16R_37150 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) A16R_37160 ENOG4105W8X HesB YadR YfhF-family protein A16R_37220 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) A16R_37240 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen A16R_37250 ENOG4108JJA ABC, transporter A16R_37260 ENOG4108I0Z Aconitate hydratase A16R_37310 ENOG4105E5W Transporter A16R_37330 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) A16R_37360 ENOG4107F3J Amp-dependent synthetase and ligase A16R_37370 ENOG4107ZYJ bioY protein A16R_37380 ENOG4105CEY Amp-dependent synthetase and ligase A16R_37470 ENOG4107AYK membrAne A16R_37490 ENOG4105BZU Histidine kinase A16R_37500 ENOG4105FBA Phospholipase Carboxylesterase A16R_37510 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase A16R_37520 ENOG4105CK7 Sodium proline symporter A16R_37530 ENOG4105CBC glutamate synthase A16R_37540 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A16R_37550 ENOG4108VJ1 Transcriptional regulator (CarD family A16R_37560 ENOG4108903 Formimidoylglutamase A16R_37610 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) A16R_37750 ENOG4107QIV Cytochrome c biogenesis protein A16R_37770 ENOG4107RSM transcriptional regulator A16R_37780 ENOG4105VAW lrga family A16R_37790 ENOG41067MG lrgb family A16R_37910 ENOG4105BZ1 (ABC) transporter A16R_37950 ENOG4105D7V transposase A16R_37980 ENOG4105D5T phosphonate abc transporter A16R_38010 ENOG4105CGH 5'-nucleotidase A16R_38030 ENOG4108SVB resolvase A16R_38070 ENOG4105K7K Transcriptional regulator A16R_38160 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase A16R_38170 ENOG4105XSJ toxin secretion phage lysis holin A16R_38590 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) A16R_38810 ENOG4105C5F glutamine synthetase A16R_38820 ENOG4105KV4 Transcriptional regulator A16R_38830 ENOG4105CXI aluminum resistance protein A16R_38860 ENOG4105EN6 Membrane A16R_38870 ENOG4106F1P AAA ATPase, central domain protein A16R_38930 ENOG41069ER domain protein A16R_38940 ENOG4105DM4 PTS System A16R_38950 ENOG4105DE4 1-phosphofructokinase A16R_38960 ENOG4105E98 transcriptional regulator DeoR family A16R_39000 ENOG4108SJC Membrane A16R_39030 ENOG4105C85 amino acid A16R_39070 ENOG4105TMB Formate nitrite transporter A16R_39080 ENOG4105K70 DNA-binding protein A16R_39090 ENOG4105C59 p-type ATPase A16R_39100 ENOG410681U heavy metal transport detoxification protein A16R_39110 ENOG4105VPX protein, conserved in bacteria A16R_39130 ENOG4105NIV Esterase A16R_39140 ENOG4105E0A ABC, transporter A16R_39190 ENOG4105CGK Exodeoxyribonuclease III A16R_39210 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A16R_39220 ENOG4105D03 DNA-3-methyladenine glycosylase II A16R_39290 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_39300 ENOG4105BZU Histidine kinase A16R_39350 ENOG41067MG lrgb family A16R_39380 ENOG4107TTQ Alpha beta hydrolase fold A16R_39390 ENOG4107YEI lmbE family A16R_39440 ENOG4105F0V Cell wall hydrolase A16R_39450 ENOG4107R6R udp-galactopyranose mutase A16R_39460 ENOG4105E0M Sulfatase A16R_39480 ENOG410890F Dynamin family A16R_39500 ENOG4107QHE Choloylglycine hydrolase A16R_39550 ENOG4105DA5 (ABC) transporter A16R_39600 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) A16R_39610 ENOG4105DQU oxidoreductase, subunit beta A16R_39620 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein A16R_39630 ENOG4108IGT Dipeptidase A16R_39640 ENOG4105MCT stage V sporulation protein S A16R_39650 ENOG4105D48 metallophosphoesterase A16R_39700 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase A16R_39730 ENOG4105XZV Protein of unknown function (DUF3243) A16R_39740 ENOG4108RKS Short-chain dehydrogenase reductase Sdr A16R_39780 ENOG4105UIB (ABC) transporter A16R_39790 ENOG4105UIB (ABC) transporter A16R_39820 ENOG4105DIH basic membrane A16R_39830 ENOG4105FDP GntR family transcriptional regulator A16R_39840 ENOG4107QZI cell division protein FtsK A16R_39860 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit A16R_39880 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A16R_39900 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) A16R_39910 ENOG4108S0H Dipicolinic acid synthetase, b subunit A16R_39920 ENOG4105E35 Dipicolinate synthase subunit A A16R_39940 ENOG4105C1V Peptidase, M16 A16R_39980 ENOG4105DTN riboflavin biosynthesis protein ribF A16R_40020 ENOG4105W7A Protein of unknown function (DUF503) A16R_40040 ENOG4105VHM ribosomal protein A16R_40060 ENOG4105CHV Transcription elongation factor NusA A16R_40080 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) A16R_40100 ENOG4105DZP Membrane-associated zinc metalloprotease A16R_40110 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) A16R_40120 ENOG4105KNE Phosphatidate cytidylyltransferase A16R_40130 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) A16R_40210 ENOG4108HE4 integrase family A16R_40260 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha A16R_40290 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) A16R_40340 ENOG4105VB6 UPF0109 protein A16R_40380 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) A16R_40430 ENOG4105CHR reductase A16R_40440 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase A16R_40480 ENOG4105CB5 ATP-dependent DNA helicase recG A16R_40490 ENOG4105DP4 dak2 domain fusion protein ylov A16R_40500 ENOG4108ZAA Alkaline-shock protein A16R_40520 ENOG4105FJ0 thiamine A16R_40530 ENOG4105DJV ribulose-phosphate 3-epimerase A16R_40560 ENOG4105D9P serine threonine protein kinase A16R_40570 ENOG4108ZF3 Phosphatase A16R_40590 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B A16R_40620 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) A16R_40630 ENOG4105C25 Primosomal protein n' A16R_40640 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase A16R_40680 ENOG4105DSJ YicC domain protein A16R_40700 ENOG4105F23 Fibronectin-binding protein A16R_40710 ENOG4105DC7 peptidase M24 A16R_40830 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain A16R_40890 ENOG4105C34 Pseudouridine synthase A16R_40920 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) A16R_40940 ENOG4105DBK s4 domain protein A16R_40950 ENOG41067XK integral membrane protein A16R_40970 ENOG4105DFA alanine racemase domain protein A16R_40980 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase A16R_40990 ENOG4105WR5 sporulation protein, YlmC YmxH family A16R_41010 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_41030 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) A16R_41040 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) A16R_41050 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) A16R_41060 ENOG4105D4A Cell wall formation (By similarity) A16R_41090 ENOG4105CNI cell division protein FtsW A16R_41120 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) A16R_41130 ENOG4105CJN penicillin-binding protein A16R_41140 ENOG4105CJN penicillin-binding protein A16R_41150 ENOG41068DC Essential cell division protein (By similarity) A16R_41220 ENOG4105KNH Nucleic acid-binding protein A16R_41320 ENOG4105XSJ toxin secretion phage lysis holin A16R_41510 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) A16R_41530 ENOG4105CAR Terminase, large subunit A16R_41700 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) A16R_41730 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_41830 ENOG4108IMY Transcriptional regulator A16R_41900 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) A16R_41920 ENOG41063PX domain protein A16R_41930 ENOG4105D78 K07001 NTE family protein A16R_41940 ENOG4105H20 Sporulation integral membrane protein YlbJ A16R_41960 ENOG4106H78 methyltransferase A16R_42010 ENOG4107TB6 phosphoglycerate mutase A16R_42040 ENOG4106UY4 Inherit from COG: Scp-like extracellular A16R_42140 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) A16R_42150 ENOG4105CNI cell division protein FtsW A16R_42180 ENOG4108IAB Phoh family A16R_42220 ENOG4105QA2 A16R_42230 ENOG4105CI3 gtp-binding protein typa A16R_42250 ENOG4105ECY inositol monophosphatase A16R_42290 ENOG4105CXN decarboxylase A16R_42370 ENOG4105C7S Dehydrogenase A16R_42380 ENOG4105CPP Dehydrogenase, E1 component A16R_42410 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) A16R_42420 ENOG4108X4Q Hydrolase A16R_42440 ENOG4105CN5 Metallo-Beta-Lactamase A16R_42450 ENOG4107ZYR domain protein A16R_42520 ENOG4108XRC Protein of unknown function (DUF458) A16R_42540 ENOG4107IN1 Protein of unknown function (DUF1797) A16R_42580 ENOG4105EPM Diguanylate phosphodiesterase A16R_42590 ENOG4105K6S Short-chain dehydrogenase reductase Sdr A16R_42620 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) A16R_42640 ENOG4105UIN A16R_42780 ENOG4108HGU Histidine kinase A16R_42800 ENOG4105CHM Aminotransferase A16R_42820 ENOG4105FKQ transcriptional regulator A16R_42840 ENOG4105EG2 ABC transporter, permease A16R_42860 ENOG4107FKK extracellular solute-binding protein family 1 A16R_42880 ENOG4105CG3 alpha amylase, catalytic region A16R_42960 ENOG4105CHU acetyl-coa acetyltransferase A16R_43030 ENOG4105K7K Transcriptional regulator A16R_43040 ENOG4105DTD Dehydrogenase A16R_43060 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) A16R_43080 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase A16R_43130 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) A16R_43180 ENOG4106TD9 Diguanylate cyclase A16R_43220 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) A16R_43250 ENOG4105CID antiterminator A16R_43270 ENOG4105FDP GntR family transcriptional regulator A16R_43290 ENOG4105CE4 GlcNAc 6-P deacetylase A16R_43360 ENOG4107ZE5 PPIases accelerate the folding of proteins A16R_43370 ENOG4105PTM secreted protein A16R_43380 ENOG4105J7I hydrolase A16R_43400 ENOG4105G6R Stage v sporulation protein ae A16R_43420 ENOG4105CZ3 stage V sporulation protein ad A16R_43430 ENOG41090VF Stage v sporulation protein ac A16R_43470 ENOG4105C8J )-transporter A16R_43480 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_43500 ENOG41082AN stage II sporulation protein A16R_43510 ENOG4105DZ1 carboxypeptidase A16R_43530 ENOG4105DVE abc transporter atp-binding protein A16R_43590 ENOG4105D7N magnesium and cobalt transport protein CorA A16R_43640 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A16R_43660 ENOG4105I3K Ferric uptake regulator, Fur family A16R_43670 ENOG4105MZ9 stage II sporulation protein m A16R_43710 ENOG4105CPC Aldo Keto reductase A16R_43730 ENOG4105RHY Pfam:UPF0157 A16R_43780 ENOG4107SKW Inherit from COG: Alpha beta hydrolase A16R_43800 ENOG4105ETE Transcriptional regulator (LacI family A16R_43810 ENOG4108YM7 Gcn5-related n-acetyltransferase A16R_43850 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) A16R_43860 ENOG4108R6K riboflavin synthase, subunit alpha A16R_43900 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) A16R_43910 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A16R_43920 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A16R_43930 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) A16R_43950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) A16R_43980 ENOG4105DFD Na H antiporter A16R_43990 ENOG4105CGH 5'-nucleotidase A16R_44070 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) A16R_44100 ENOG4108IXY short-chain dehydrogenase reductase A16R_44110 ENOG41069FQ Metallo-beta-lactamase superfamily A16R_44130 ENOG4105II7 pyrroline-5-carboxylate reductase A16R_44140 ENOG4105EJQ L-serine dehydratase A16R_44190 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) A16R_44200 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) A16R_44210 ENOG4105D9U N-acetyltransferase A16R_44230 ENOG4108VZI ErfK ybiS ycfS ynhG family protein A16R_44240 ENOG4108QEG Membrane A16R_44250 ENOG4105CDA abc transporter atp-binding protein A16R_44260 ENOG4105E5Q amino acid AbC transporter A16R_44270 ENOG4108HW3 (ABC) transporter A16R_44300 ENOG4105G7B Protein of unknown function (DUF2992) A16R_44310 ENOG4105E09 nadh pyrophosphatase A16R_44330 ENOG4105C7S Dehydrogenase A16R_44340 ENOG4105CPP Dehydrogenase, E1 component A16R_44380 ENOG4107RDP Dehydrogenase A16R_44420 ENOG4108QXE glycerophosphoryl diester phosphodiesterase A16R_44450 ENOG4107QQR Sporulation A16R_44460 ENOG4105S1Z Stage IV sporulation protein B A16R_44470 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) A16R_44490 ENOG4105DX0 Hemolysin A A16R_44510 ENOG4105CTB Polyprenyl synthetase A16R_44570 ENOG4108ZSR alkaline shock protein A16R_44580 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase A16R_44620 ENOG410644B Stage III sporulation protein af A16R_44640 ENOG4105KQ4 Stage iii sporulation protein ad A16R_44650 ENOG4108CQH stage III sporulation protein AC A16R_44660 ENOG4105KR5 Stage iii sporulation protein A16R_44670 ENOG4105CD2 stage iii sporulation protein aa A16R_44710 ENOG4105DC7 peptidase M24 A16R_44740 ENOG4105CBJ Metal-dependent enzyme A16R_44760 ENOG4107YBY Hydrolase A16R_44820 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) A16R_44830 ENOG4105WZW rhodanese family A16R_44870 ENOG41080TC multidrug resistance protein A16R_44950 ENOG4105CJ1 ABC, transporter A16R_44960 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family A16R_45020 ENOG4105C0D helicase A16R_45280 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) A16R_45290 ENOG4105C3R Methionine synthase A16R_45310 ENOG4105C28 cystathionine A16R_45320 ENOG4105C28 cystathionine A16R_45360 ENOG4105C5X domain protein A16R_45380 ENOG4105DKQ ROK family A16R_45400 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase A16R_45430 ENOG4108UTW Plays a role in the regulation of phosphate uptake A16R_45440 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) A16R_45450 ENOG4105E2Z phosphate ABC transporter (Permease A16R_45460 ENOG4105C8U phosphate abc transporter A16R_45470 ENOG4105PWN phosphate abc transporter A16R_45480 ENOG4107RF6 penicillin-binding protein A16R_45500 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A16R_45550 ENOG4105N80 Ferric uptake regulator, Fur family A16R_45570 ENOG4105FDK ABC transporter A16R_45590 ENOG4108JYZ YitT family A16R_45660 ENOG4105EGD dinuclear metal center protein, YbgI family A16R_45690 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_45790 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) A16R_45800 ENOG4105KG3 cytidine deaminase A16R_45810 ENOG4107YR5 Diacylglycerol kinase A16R_45830 ENOG4105CTJ Metal Dependent Phosphohydrolase A16R_45840 ENOG4105C9A Phoh family A16R_45860 ENOG41068P3 sporulation protein YqfC A16R_45870 ENOG4105KTH gatB Yqey A16R_45890 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) A16R_45900 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) A16R_45940 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ A16R_45960 ENOG4105CSA Coproporphyrinogen iii oxidase A16R_45970 ENOG4105KVH Transcriptional regulator A16R_46020 ENOG4105TQK DNA polymerase iii, delta' subunit A16R_46040 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 A16R_46060 ENOG4108UK2 deaminase A16R_46070 ENOG4105KQC Competence protein A16R_46120 ENOG4108WF2 Metal Dependent Phosphohydrolase A16R_46160 ENOG4105CQW ribosome biogenesis GTPase YqeH A16R_46170 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase A16R_46200 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_46240 ENOG4108TVJ Nitroreductase A16R_46280 ENOG4105G6Z alkaline phosphatase A16R_46300 ENOG4108MUZ hydrolase A16R_46380 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin A16R_46400 ENOG4105MIR Phenylalanine 4-monooxygenase A16R_46420 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_46430 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_46520 ENOG4105S6R Iron-hydroxamate transporter permease subunit A16R_46530 ENOG4108V5C ABC transporter A16R_46550 ENOG4108EKI Dehydrogenase A16R_46640 ENOG4107XRG penicillin-binding protein A16R_46670 ENOG4105CFP Peptidase U32 A16R_46680 ENOG4105XYU peptidase (U32 family) A16R_46690 ENOG4108VQJ O-methyltransferase A16R_46700 ENOG4105HHA aminodeoxychorismate lyase A16R_46740 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) A16R_46760 ENOG4105C02 permease A16R_46790 ENOG41060CR A16R_46800 ENOG4105C7H Helicase, RecD TraA family A16R_46820 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) A16R_46830 ENOG4105C3J Cysteine desulfurase A16R_46860 ENOG4105D1H recombination factor protein RarA A16R_46870 ENOG4108VCI transcription factor, rsfa family A16R_46880 ENOG4105CUZ uba thif-type nad fad binding protein A16R_46900 ENOG4105CUT histidyl-tRNA synthetase A16R_46930 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) A16R_46950 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) A16R_46960 ENOG41076HS cation diffusion facilitator family transporter A16R_46970 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) A16R_46990 ENOG4105CKP Polysaccharide Biosynthesis Protein A16R_47000 ENOG4108QG2 Membrane A16R_47020 ENOG4105VIE preprotein translocase, subunit YajC A16R_47050 ENOG41061AI Protein of unknown function (DUF2905) A16R_47080 ENOG4108HUF Transporter A16R_47100 ENOG4108IPJ Membrane A16R_47110 ENOG4108IPJ Membrane A16R_47120 ENOG41082BM Transcriptional regulator, arsr family A16R_47180 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase A16R_47190 ENOG4108IYU L-aspartate oxidase A16R_47230 ENOG4108RPX mosc domain containing protein A16R_47240 ENOG4105CQC Prephenate dehydratase A16R_47280 ENOG4105EWM Histidine kinase A16R_47310 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control A16R_47340 ENOG4105X36 (ribosomal) protein A16R_47360 ENOG4105C03 ribonuclease A16R_47390 ENOG4107QMS site-determining protein A16R_47420 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) A16R_47430 ENOG4105DFF Rod shape-determining protein mreb A16R_47470 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase A16R_47480 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) A16R_47500 ENOG41068KH stage VI sporulation protein D A16R_47520 ENOG4105D52 delta-aminolevulinic acid dehydratase A16R_47570 ENOG4105K56 Transcriptional regulator A16R_47610 ENOG4108IUQ atp-dependent protease A16R_47660 ENOG4108QCI YvbH-like oligomerisation region A16R_47710 ENOG4105M59 Phosphodiesterase, mj0936 family A16R_47720 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) A16R_47750 ENOG4108XJQ germination protein A16R_47770 ENOG4108PCX Major Facilitator A16R_47800 ENOG4105KBX Transcriptional regulator, TetR family A16R_47830 ENOG4105PFC Transcriptional regulator A16R_47860 ENOG4105DZC cytosine deaminase A16R_47870 ENOG4105DZC cytosine deaminase A16R_47880 ENOG4105DEF Extracellular solute-binding protein, family 5 A16R_47890 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component A16R_47920 ENOG4108JQ7 (ABC) transporter A16R_47930 ENOG4108HRK Histidine kinase A16R_47940 ENOG4105DY9 regulatoR A16R_47970 ENOG41067S9 phage shock protein C, PspC A16R_47980 ENOG4108JCI Transcriptional regulator A16R_48000 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) A16R_48010 ENOG4108Z40 Transcriptional regulator A16R_48020 ENOG4105RHA ABC transporter, permease A16R_48030 ENOG4108IUX (ABC) transporter A16R_48040 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family A16R_48070 ENOG4105E14 MotA TolQ exbB proton channel A16R_48080 ENOG4108VXD carboxy-peptidase A16R_48100 ENOG4105E33 succinate dehydrogenase A16R_48130 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit A16R_48160 ENOG4105K63 Thioredoxin A16R_48170 ENOG4105C10 Electron transfer flavoprotein A16R_48180 ENOG4105BZJ Electron transfer flavoprotein A16R_48190 ENOG41060WC Enoyl-CoA hydratase A16R_48200 ENOG4107Z3H Transcriptional regulator, TetR family A16R_48210 ENOG4105CEY Amp-dependent synthetase and ligase A16R_48240 ENOG4105J76 Periplasmic binding protein A16R_48250 ENOG4105S6R Iron-hydroxamate transporter permease subunit A16R_48340 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A16R_48370 ENOG4105DR4 Methyltransferase A16R_48420 ENOG4105KFN sortase, SrtB family A16R_48430 ENOG4105E0A ABC, transporter A16R_48490 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) A16R_48510 ENOG4105FE9 pseudouridine synthase A16R_48530 ENOG4105DCG PHP domain protein A16R_48590 ENOG4105C5S asparaginyl-tRNA synthetase A16R_48600 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) A16R_48620 ENOG4108RWN rrna methyltransferase A16R_48690 ENOG4105C0R drug resistance transporter emrb qaca subfamily A16R_48700 ENOG4105CW7 secretion protein, HlyD family A16R_48710 ENOG4108JGH Tetr family transcriptional regulator A16R_48720 ENOG4105CN9 Peptidase m42 family protein A16R_48760 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) A16R_48770 ENOG4105C22 threonyL-tRNA synthetase A16R_48780 ENOG4108TDW sporulation protein YtxC A16R_48820 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) A16R_48840 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase A16R_48850 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) A16R_48870 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) A16R_48880 ENOG4105C2M dna polymerase I A16R_48890 ENOG4105BZU Histidine kinase A16R_48900 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A16R_48950 ENOG4108HMX isocitrate dehydrogenase (NADP) A16R_48960 ENOG4105BZN citrate synthase A16R_48980 ENOG4108REF Sporulation integral membrane protein ytvi A16R_49040 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family A16R_49050 ENOG4105C6K Malic enzyme A16R_49060 ENOG4105C0B DNA polymerase III (alpha subunit) A16R_49070 ENOG4105VV2 A16R_49090 ENOG4105SFS phosphoesterase RecJ domain protein A16R_49170 ENOG4105DC7 peptidase M24 A16R_49240 ENOG4105Z7P Acetyltransferase (GNAT) family A16R_49250 ENOG41082W1 Cupin 2, conserved barrel domain protein A16R_49270 ENOG4105VZ8 Transcriptional regulator A16R_49310 ENOG4107YZX Universal stress protein A16R_49400 ENOG4108JYZ YitT family A16R_49440 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) A16R_49460 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) A16R_49470 ENOG4105KBJ sporulation protein ytfj A16R_49500 ENOG4105EFZ amidohydrolase A16R_49520 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) A16R_49580 ENOG4106KR7 LysR family Transcriptional regulator A16R_49630 ENOG4105C28 cystathionine A16R_49670 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) A16R_49690 ENOG4105EMN RNA polymerase sigma factor A16R_49720 ENOG4105F1V Acetoin utilization protein A16R_49730 ENOG4105W87 Cbs domain A16R_49740 ENOG4105DGU Histone deacetylase A16R_49760 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A16R_49780 ENOG4107SNB ankyrin repeat protein YahD A16R_49790 ENOG4105EP9 oxidoreductase A16R_49850 ENOG4105ETE Transcriptional regulator (LacI family A16R_49890 ENOG4105C88 aminopeptidase A16R_49980 ENOG4108VDD TRNA binding domain protein A16R_50040 ENOG4105C8F Beta-lactamase domain protein A16R_50070 ENOG4108V15 phosphotransferase enzyme family A16R_50080 ENOG4108IUM Glycogen debranching enzyme A16R_50100 ENOG4107QSE Dipeptidase A16R_50110 ENOG4107QSE Dipeptidase A16R_50120 ENOG4105YW5 deoR family transcriptional regulator A16R_50150 ENOG4105CBX hi0933 family A16R_50230 ENOG4108VJ1 Transcriptional regulator (CarD family A16R_50240 ENOG4107EXU Short-chain dehydrogenase reductase Sdr A16R_50250 ENOG4105CSC Glucose uptake protein A16R_50280 ENOG4108ZAF Molybdopterin A16R_50290 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein A16R_50300 ENOG4105CVM Molybdenum cofactor synthesis domain protein A16R_50320 ENOG4105D06 uba thif-type nad fad binding protein A16R_50390 ENOG41085GJ domain protein A16R_50410 ENOG4105DWV Homoserine O-trans-acetylase A16R_50450 ENOG4108B31 Spore germination protein A16R_50520 ENOG410605W Major Facilitator A16R_50550 ENOG4105NCW Trka-c domain protein A16R_50580 ENOG4105C19 ABC transporter A16R_50620 ENOG4105N5T Radical SAM Protein A16R_50640 ENOG4105DA5 (ABC) transporter A16R_50710 ENOG4105E8V Alpha Beta Hydrolase Fold protein A16R_50720 ENOG4108Z0R Transferase A16R_50730 ENOG4105YVM Phosphoesterase, PA-phosphatase related A16R_50740 ENOG4105BZF Glycosyl transferase (Group 1 A16R_50760 ENOG4108RIR Molybdenum cofactor biosynthesis protein A16R_50890 ENOG4105EGD dinuclear metal center protein, YbgI family A16R_50900 ENOG4105BZU Histidine kinase A16R_50910 ENOG4105BZU Histidine kinase A16R_50920 ENOG4107S9D Alpha beta hydrolase A16R_50970 ENOG4105D2X ABC transporter substrate-binding protein A16R_50990 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component A16R_51090 ENOG4108V2W Carbonate dehydratase A16R_51100 ENOG4105C4M (Ubiquinol oxidase) subunit I A16R_51110 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A16R_51200 ENOG41087YS Phage shock protein A A16R_51260 ENOG4105BZU Histidine kinase A16R_51270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_51320 ENOG4108UGV hypoxanthine phosphoribosyltransferase A16R_51330 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) A16R_51400 ENOG4107ZTW SNARE associated Golgi A16R_51430 ENOG4105C19 ABC transporter A16R_51550 ENOG4105C6Z Gluconate A16R_51560 ENOG4105FDP GntR family transcriptional regulator A16R_51600 ENOG41069H0 dihydroorotase EC 3.5.2.3 A16R_51660 ENOG4105DTQ mandelate racemase muconate lactonizing A16R_51680 ENOG4108IPT Naphthoate synthase A16R_51690 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) A16R_51700 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) A16R_51710 ENOG4105E4F Isochorismate synthase A16R_51720 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase A16R_51740 ENOG4105VEQ Cold shock protein A16R_51790 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) A16R_51810 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) A16R_51830 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) A16R_52020 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation A16R_52090 ENOG4105KT7 mgtC SapB transporter A16R_52130 ENOG4107QYV phosphohexose isomerase A16R_52140 ENOG4105WG9 Conserved Protein A16R_52160 ENOG4105CHM Aminotransferase A16R_52170 ENOG4108ZB6 transcriptional regulator AsnC family A16R_52180 ENOG4105C5I Dehydrogenase A16R_52190 ENOG4108MUZ hydrolase A16R_52210 ENOG4105C87 Aminotransferase class I and II A16R_52240 ENOG4105Y38 Kinase-associated protein B A16R_52260 ENOG4107R3E Citrate transporter A16R_52300 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) A16R_52310 ENOG4105KA0 thioesterase Superfamily protein A16R_52350 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase A16R_52390 ENOG41069ER domain protein A16R_52420 ENOG4105CEP NADH dehydrogenase A16R_52480 ENOG4105EWC Purine nucleoside phosphorylase A16R_52520 ENOG4108YX9 iron--sulfur cluster insertion protein erpA A16R_52570 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A16R_52580 ENOG4105C4B ABC transporter, permease A16R_52590 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA A16R_52680 ENOG41083MR nifu domain-containing protein A16R_52710 ENOG4108W5N phosphatidylglycerophosphatase a A16R_52740 ENOG4105DYS nad(p)h dehydrogenase (quinone) A16R_52750 ENOG4105D4U had-superfamily hydrolase, subfamily iia A16R_52780 ENOG4105CBT Fructose-1,6-bisphosphatase A16R_52810 ENOG4105MMD transcriptional regulator A16R_52820 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) A16R_52830 ENOG4107TXC Transcriptional regulator A16R_52840 ENOG41090T1 Membrane A16R_52890 ENOG4105FAA peptidase M23 A16R_52910 ENOG4105KZD Domain of unknown function (DUF1805) A16R_52920 ENOG4107R8B 5'-nucleotidase A16R_52960 ENOG4105DIW FeS assembly protein SUFB A16R_52970 ENOG4108UNV SUF system FeS assembly protein, NifU family A16R_52980 ENOG4105C9B Cysteine desulfurase A16R_52990 ENOG4105JRK feS assembly protein SufD A16R_53010 ENOG4105C3K feS assembly ATPase SufC A16R_53020 ENOG4105D01 (LipO)protein A16R_53030 ENOG4105D01 (LipO)protein A16R_53040 ENOG4108UMI ABC transporter, permease A16R_53110 ENOG41080E8 Transcriptional regulator, Spx MgsR family A16R_53190 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) A16R_53240 ENOG4108W8B Beta-lactamase domain protein A16R_53250 ENOG4105C1G acyl-Coa dehydrogenase A16R_53270 ENOG4105CHU acetyl-coa acetyltransferase A16R_53300 ENOG4105DZ1 carboxypeptidase A16R_53340 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer A16R_53380 ENOG4108SUT Major Facilitator Superfamily A16R_53390 ENOG4107R7I amino acid A16R_53410 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins A16R_53430 ENOG4107AYK membrAne A16R_53500 ENOG4107ZTW SNARE associated Golgi A16R_53520 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein A16R_53530 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_53540 ENOG4105BZU Histidine kinase A16R_53560 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) A16R_53590 ENOG4105VG1 fes assembly suf system protein A16R_53600 ENOG4105D4Y metalloprotease A16R_53640 ENOG4107S91 Sodium hydrogen exchanger A16R_53650 ENOG4105NCW Trka-c domain protein A16R_53670 ENOG4108RMU ferritin dps family protein A16R_53710 ENOG4108URH decarboxylase A16R_53780 ENOG4105D9N nucleoside A16R_53810 ENOG4108RYK Nad-dependent epimerase dehydratase A16R_53860 ENOG4105CV8 reductase A16R_53870 ENOG4105F27 Major Facilitator A16R_53880 ENOG4105KVH Transcriptional regulator A16R_53910 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) A16R_53920 ENOG4105D4A Cell wall formation (By similarity) A16R_53940 ENOG4105C8Q Methyl-accepting chemotaxis A16R_53960 ENOG4105WMR Protein CrcB homolog A16R_53970 ENOG4105WMR Protein CrcB homolog A16R_54000 ENOG4108MK9 spermidine N(1)-acetyltransferase A16R_54010 ENOG4108VY7 phosphate-starvation-inducible protein PsiE A16R_54040 ENOG4108IPW abc transporter atp-binding protein A16R_54050 ENOG4105CM4 permease protein A16R_54110 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) A16R_54130 ENOG4105XZU Preprotein translocase, subunit SecG A16R_54140 ENOG41067MG lrgb family A16R_54330 ENOG4105EFC phage portal protein HK97 family A16R_54380 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A16R_54420 ENOG4105CP7 Triose-phosphate isomerase A16R_54470 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_54510 ENOG41090VF Stage v sporulation protein ac A16R_54520 ENOG4105CZ3 stage V sporulation protein ad A16R_54550 ENOG4105H67 Protein of unknown function (DUF421) A16R_54560 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) A16R_54570 ENOG4105KRI phosphocarrier protein (HPr A16R_54590 ENOG4105CHW UPF0052 protein A16R_54610 ENOG4108Z4K mutator MutT protein A16R_54630 ENOG4105C3M thioredoxin reductase A16R_54650 ENOG4108S4C acetyltransferase A16R_54700 ENOG41086DT Membrane protein of unknown function A16R_54720 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) A16R_54730 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) A16R_54740 ENOG4105D7V transposase A16R_54770 ENOG4107TXC Transcriptional regulator A16R_54820 ENOG4105HMI Membrane A16R_54830 ENOG4105DUM transcriptional regulator, lysR family A16R_54850 ENOG4108WS4 fmn reductase A16R_54880 ENOG4105BZ1 (ABC) transporter A16R_54900 ENOG4105CN1 protease A16R_54910 ENOG4105CRP Part of the ABC transporter FtsEX involved in A16R_54920 ENOG4105CAK Cell division ATP-binding protein ftsE A16R_54980 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving A16R_54990 ENOG4105MS2 ribosomal subunit Interface protein A16R_55010 ENOG4105VEQ Cold shock protein A16R_55020 ENOG41081UC Inherit from COG: Competence protein A16R_55050 ENOG4105KVH Transcriptional regulator A16R_55070 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein A16R_55080 ENOG4108KGH TRANSCRIPTIONal A16R_55090 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase A16R_55100 ENOG4105C6Y Udp-glucose 6-dehydrogenase A16R_55110 ENOG4105ESV Glycosyl transferase, family 4 A16R_55130 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family A16R_55160 ENOG410901P UPF0249 protein A16R_55170 ENOG4105F8D glycoside hydrolase family 4 A16R_55180 ENOG4105VCP PTS System A16R_55190 ENOG4105CK1 PTS System A16R_55210 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) A16R_55220 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) A16R_55230 ENOG4105VCP PTS System A16R_55250 ENOG4105VZJ PTS System A16R_55280 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase A16R_55290 ENOG4105ECB domain protein A16R_55300 ENOG4107RSM transcriptional regulator A16R_55400 ENOG4105DAA L-lactate A16R_55420 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) A16R_55440 ENOG4105E0M Sulfatase A16R_55540 ENOG4105C94 Transporter A16R_55550 ENOG41069ER domain protein A16R_55600 ENOG4105KBK Zinc finger, swim domain protein A16R_55610 ENOG4105C0D helicase A16R_55670 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A16R_55690 ENOG4107RBB ABC transporter, permease A16R_55700 ENOG4105C19 ABC transporter A16R_55750 ENOG4105CXY transporter A16R_55780 ENOG4105BZU Histidine kinase A16R_55790 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_55800 ENOG4105CMR udp-glucose 4-epimerase A16R_55840 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase A16R_55850 ENOG4105EY8 ABC transporter A16R_55990 ENOG4105FRN stage II sporulation protein A16R_56020 ENOG4105DY9 regulatoR A16R_56030 ENOG4108IUW ABC transporter A16R_56070 ENOG4106778 Protein of unknown function (DUF1146) A16R_56080 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) A16R_56090 ENOG4105C8S subunit m A16R_56100 ENOG4105D65 subunit l A16R_56150 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) A16R_56160 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain A16R_56180 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain A16R_56190 ENOG4105BZU Histidine kinase A16R_56300 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) A16R_56310 ENOG41062M3 atp synthase A16R_56370 ENOG4108YZG isomerase A16R_56400 ENOG4108VGI doxx family A16R_56410 ENOG4107XC4 flavin reductase domain protein, FMN-binding A16R_56450 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) A16R_56490 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) A16R_56500 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) A16R_56530 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) A16R_56540 ENOG4105CBT Fructose-1,6-bisphosphatase A16R_56630 ENOG4105C1G acyl-Coa dehydrogenase A16R_56640 ENOG4105C1G acyl-Coa dehydrogenase A16R_56650 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase A16R_56670 ENOG4105DF6 Fe-S oxidoreductase A16R_56700 ENOG4105BZU Histidine kinase A16R_56750 ENOG4105BZU Histidine kinase A16R_56760 ENOG4105KCT ABC transporter A16R_56770 ENOG4108M15 ABC transporter A16R_56780 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) A16R_56850 ENOG4105IIU Aminopeptidase A16R_56910 ENOG410684U Domain of unknown function (DUF1934) A16R_56960 ENOG4105CYW agmatinase A16R_56980 ENOG4105DXB Major Facilitator superfamily A16R_56990 ENOG4107SWG transcriptional regulator MERR family A16R_57010 ENOG4108QXE glycerophosphoryl diester phosphodiesterase A16R_57020 ENOG4105BZ4 penicillin-binding protein A16R_57030 ENOG4108XFG YwhD family A16R_57040 ENOG4108Z4T Peptidase M50 A16R_57050 ENOG41069HH 4-oxalocrotonate tautomerase A16R_57060 ENOG4105DCI Phosphohydrolase A16R_57070 ENOG4108MES Periplasmic binding protein A16R_57080 ENOG4105E0A ABC, transporter A16R_57090 ENOG4105EHG Permease protein A16R_57110 ENOG4105DQ5 transport system permease protein A16R_57130 ENOG4108VCI transcription factor, rsfa family A16R_57160 ENOG4108IJ2 phosphate acetyltransferase A16R_57190 ENOG4108VKI Cell wall hydrolase A16R_57260 ENOG410667J hydrolase A16R_57270 ENOG4105VCH membrane A16R_57290 ENOG4108TU7 Inherit from COG: (ABC) transporter A16R_57300 ENOG4105CJ1 ABC, transporter A16R_57310 ENOG41090WU lipolytic protein G-D-S-L family A16R_57340 ENOG4105D6E homoserine dehydrogenase A16R_57390 ENOG4108Y4K DNA-binding transcriptional activator A16R_57410 ENOG4105WH1 Two component transcriptional regulator luxr family A16R_57440 ENOG4105DWF phosphomethylpyrimidine kinase A16R_57450 ENOG4105BZU Histidine kinase A16R_57460 ENOG4105VCD cytoplasmic protein A16R_57470 ENOG4105D22 carbon starvation protein A16R_57480 ENOG4105DY9 regulatoR A16R_57500 ENOG41079KZ Major Facilitator Superfamily A16R_57540 ENOG4105EN6 Membrane A16R_57580 ENOG4108S4H thioesterase Superfamily protein A16R_57610 ENOG4105JEU Glycosyl transferase, family 2 A16R_57620 ENOG4105C5H ABC transporter A16R_57670 ENOG4105CKK Glycosyl transferase, family 2 A16R_57680 ENOG41067SE Tetr family transcriptional regulator A16R_57700 ENOG4105E0X reductase A16R_57720 ENOG4106F5Q Membrane A16R_57750 ENOG4105DY9 regulatoR A16R_57760 ENOG4108HRK Histidine kinase A16R_57770 ENOG4107RGD Major Facilitator superfamily A16R_57800 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A16R_57820 ENOG4105IW1 AmiS UreI transporter A16R_57840 ENOG4105CMR udp-glucose 4-epimerase A16R_57880 ENOG4105C1J atp-dependent rna helicase A16R_57920 ENOG4105DPN Oligoendopeptidase f A16R_57960 ENOG4105C0H protease A16R_57970 ENOG4105Q2H domain protein A16R_58000 ENOG4105BZU Histidine kinase A16R_58010 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A16R_58070 ENOG4105CDU Replicative dna helicase A16R_58090 ENOG4105BZR domain protein A16R_58100 ENOG4108XMW Membrane A16R_58120 ENOG4108UUM single-stranded DNA-binding protein A16R_58140 ENOG4105C3G gtp-binding protein A16R_58150 ENOG4105VDK protein, conserved in bacteria A16R_58160 ENOG4105D8X mechanosensitive ion channel A16R_58170 ENOG4108ZDA Sporulation protein YyaC A16R_58180 ENOG4105FA0 parb-like partition protein A16R_58190 ENOG4107QJE Chromosome Partitioning Protein A16R_58230 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) A16R_58250 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins A16R_58285 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) A16R_58330 ENOG4108RE7 deoxyribonuclease A16R_58360 ENOG4105C7N Xanthine uracil vitamin C permease A16R_58370 ENOG4105C83 adenylosuccinate lyase A16R_58400 ENOG4105C5H ABC transporter A16R_58415 ENOG4108IMY Transcriptional regulator A16R_58455 ENOG4107QQG Dehydrogenase A16R_58465 ENOG4105CBC glutamate synthase A16R_58470 ENOG4107ZQN disulfide bond A16R_58495 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase A16R_58515 ENOG4108IQI permease A16R_58520 ENOG4108NHD germination protein A16R_58525 ENOG4105CE1 Ferrous iron transport protein b A16R_58555 ENOG41069ER domain protein A16R_58585 ENOG4105D4P Coproporphyrinogen iii oxidase A16R_58685 ENOG4105CAQ asparagine synthetase A16R_58690 ENOG4105BZU Histidine kinase A16R_58720 ENOG4105DPN Oligoendopeptidase f A16R_58870 ENOG4105CN5 Metallo-Beta-Lactamase A16R_58980 ENOG4105F6J Alpha beta hydrolase fold A16R_59025 ENOG41075D4 Aminoglycoside 6-adenylyltransferase A16R_59170 ENOG4107QPK )-transporter A16R_59180 ENOG4105C8J )-transporter A16R_59220 ENOG4105SZ6 Thioredoxin A16R_59255 ENOG4105BZ4 penicillin-binding protein A16R_59335 ENOG4108RZE Tetr family transcriptional regulator A16R_59390 ENOG4105CUV Homoserine Kinase A16R_59430 ENOG4107RF6 penicillin-binding protein A16R_59435 ENOG4105CJN penicillin-binding protein A16R_59455 ENOG4105FCD Major Facilitator A16R_59470 ENOG4108NRW Phospholipase, patatin family A16R_59510 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) A16R_59540 ENOG4105C9U ATP-dependent DNA helicase RecQ A16R_59565 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) A16R_59595 ENOG4105CHM Aminotransferase A16R_59655 ENOG4105ECK Fatty Acid Desaturase A16R_59700 ENOG4105II7 pyrroline-5-carboxylate reductase A16R_59765 ENOG4106P55 Transcriptional regulator A16R_59795 ENOG41082W1 Cupin 2, conserved barrel domain protein A16R_59825 ENOG4106UW1 Major Facilitator superfamily A16R_59875 ENOG4105KAF membrAne A16R_59965 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase A16R_59970 ENOG4105BZ1 (ABC) transporter A16R_60030 ENOG4108JQ9 ABC transporter A16R_60040 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) A16R_60045 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination A16R_60050 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) A16R_60055 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) A16R_60070 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) A16R_60200 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family A16R_60300 ENOG41069ZM Protein of unknown function (DUF2624) A16R_60310 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) A16R_60320 ENOG4105DXX methyltransferase A16R_60325 ENOG410812S Rna-binding protein A16R_60345 ENOG4105C28 cystathionine A16R_60400 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) A16R_60420 ENOG4105FS0 cytoplasmic membrane protein A16R_60470 ENOG4107S91 Sodium hydrogen exchanger A16R_60520 ENOG41086D8 Transcriptional regulator A16R_60530 ENOG4107PBV potassium channel A16R_60585 ENOG4105D9N nucleoside A16R_60610 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) A16R_60620 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) A16R_60650 ENOG4105MT0 Sporulation transcriptional regulator spoiiid A16R_60665 ENOG4108ZXQ stage ii sporulation protein r A16R_60670 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) A16R_60675 ENOG4105EMN RNA polymerase sigma factor A16R_60680 ENOG4105DQ5 transport system permease protein A16R_60695 ENOG4106YBV Methyl-accepting chemotaxis A16R_60705 ENOG4108UT2 hemolysin iii A16R_60760 ENOG4105EKQ RNA-directed DNA polymerase A16R_60840 ENOG4105EKQ RNA-directed DNA polymerase A16R_60960 ENOG4105CNU cell division protein FtsK A16R_61185 ENOG4105DHF Membrane A16R_61210 ENOG4106AKK s-layer domain-containing protein A16R_61215 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase A16R_61240 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase A16R_61245 ENOG4105C6Y Udp-glucose 6-dehydrogenase A16R_61260 ENOG4105DQ6 Transposase A16R_61300 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) A16R_61415 ENOG4105KRN Transcriptional regulator, abrb family A16R_61425 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A16R_61455 ENOG4108IBT Inherit from COG: transposase A16R_61465 ENOG4105DQ6 Transposase A16R_61485 ENOG4108MEK Metal-binding protein YodA A16R_61495 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) A16R_61525 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)